ORF_ID e_value Gene_name EC_number CAZy COGs Description
AFANOAJP_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AFANOAJP_00002 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AFANOAJP_00003 1.1e-29 yyzM S Protein conserved in bacteria
AFANOAJP_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AFANOAJP_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AFANOAJP_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AFANOAJP_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
AFANOAJP_00008 2.7e-61 divIC D Septum formation initiator
AFANOAJP_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
AFANOAJP_00011 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AFANOAJP_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AFANOAJP_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFANOAJP_00014 4e-136 L Transposase
AFANOAJP_00015 2.5e-92 L Transposase
AFANOAJP_00016 3e-51 L transposition
AFANOAJP_00029 5.3e-11
AFANOAJP_00035 1.3e-140 mreC M Involved in formation and maintenance of cell shape
AFANOAJP_00036 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AFANOAJP_00037 2e-96 usp 3.5.1.28 CBM50 S CHAP domain
AFANOAJP_00038 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFANOAJP_00039 2.5e-26
AFANOAJP_00040 4.5e-219 araT 2.6.1.1 E Aminotransferase
AFANOAJP_00041 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
AFANOAJP_00042 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AFANOAJP_00043 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFANOAJP_00044 1.2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AFANOAJP_00045 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFANOAJP_00046 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AFANOAJP_00047 3.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AFANOAJP_00048 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AFANOAJP_00049 7.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AFANOAJP_00050 1e-90 L transposase activity
AFANOAJP_00051 3.5e-50 L transposition
AFANOAJP_00052 2e-32 L Integrase core domain protein
AFANOAJP_00053 2.3e-161 S CHAP domain
AFANOAJP_00054 2e-241 purD 6.3.4.13 F Belongs to the GARS family
AFANOAJP_00055 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AFANOAJP_00056 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AFANOAJP_00057 9.2e-141 1.1.1.169 H Ketopantoate reductase
AFANOAJP_00058 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AFANOAJP_00059 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AFANOAJP_00060 8.2e-70 argR K Regulates arginine biosynthesis genes
AFANOAJP_00061 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
AFANOAJP_00062 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AFANOAJP_00063 1.9e-80 S Protein of unknown function (DUF3021)
AFANOAJP_00064 6.5e-63 KT phosphorelay signal transduction system
AFANOAJP_00066 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AFANOAJP_00068 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AFANOAJP_00069 2.4e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
AFANOAJP_00070 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
AFANOAJP_00071 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AFANOAJP_00072 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
AFANOAJP_00078 2.6e-10
AFANOAJP_00081 1.9e-07
AFANOAJP_00086 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFANOAJP_00087 2.3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
AFANOAJP_00088 5.5e-36 XK27_02060 S Transglycosylase associated protein
AFANOAJP_00089 2.6e-55 badR K DNA-binding transcription factor activity
AFANOAJP_00090 1e-96 S reductase
AFANOAJP_00091 2.3e-31 L Integrase core domain protein
AFANOAJP_00092 2.1e-34 L Integrase core domain protein
AFANOAJP_00093 6.4e-41 L transposition
AFANOAJP_00094 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
AFANOAJP_00095 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
AFANOAJP_00098 1.6e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
AFANOAJP_00099 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AFANOAJP_00100 5.5e-83 S Putative small multi-drug export protein
AFANOAJP_00101 2.6e-74 ctsR K Belongs to the CtsR family
AFANOAJP_00102 0.0 clpC O Belongs to the ClpA ClpB family
AFANOAJP_00103 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AFANOAJP_00104 1.7e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AFANOAJP_00105 6.7e-122 L Helix-turn-helix domain
AFANOAJP_00106 1.2e-165 L integrase core domain
AFANOAJP_00107 5.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AFANOAJP_00108 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
AFANOAJP_00109 5.9e-143 S SseB protein N-terminal domain
AFANOAJP_00110 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
AFANOAJP_00111 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFANOAJP_00112 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AFANOAJP_00115 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFANOAJP_00116 7e-92 yacP S RNA-binding protein containing a PIN domain
AFANOAJP_00117 4.4e-155 degV S DegV family
AFANOAJP_00119 1.1e-20 K helix-turn-helix
AFANOAJP_00120 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFANOAJP_00121 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AFANOAJP_00122 2.1e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
AFANOAJP_00123 4.1e-36 K sequence-specific DNA binding
AFANOAJP_00125 0.0
AFANOAJP_00126 5.4e-181 L Transposase
AFANOAJP_00127 3.2e-31 L Transposase
AFANOAJP_00128 4.7e-56 EGP Major facilitator Superfamily
AFANOAJP_00129 7.7e-112 EGP Major facilitator Superfamily
AFANOAJP_00130 5.9e-24 3.6.4.12
AFANOAJP_00131 5.4e-92 3.6.4.12 K Divergent AAA domain protein
AFANOAJP_00132 1.1e-236 L Helix-turn-helix domain of transposase family ISL3
AFANOAJP_00133 6.2e-128 tnp L DDE domain
AFANOAJP_00134 1.9e-57 L Transposase
AFANOAJP_00136 0.0 ddpA E ABC transporter substrate-binding protein
AFANOAJP_00137 2.8e-188 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFANOAJP_00138 1.8e-141 dppC P N-terminal TM domain of oligopeptide transport permease C
AFANOAJP_00139 0.0 P Belongs to the ABC transporter superfamily
AFANOAJP_00140 3e-13 mesE M Transport protein ComB
AFANOAJP_00141 2.4e-178 L transposase, IS4 family
AFANOAJP_00142 2.1e-128 tnp L DDE domain
AFANOAJP_00143 1.9e-225 nodC 2.4.1.212 GT2 M Chitin synthase
AFANOAJP_00144 2.4e-214 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFANOAJP_00145 1.8e-237 L Transposase
AFANOAJP_00146 5.7e-91 tnp L Transposase
AFANOAJP_00147 1.2e-42 capA M Bacterial capsule synthesis protein PGA_cap
AFANOAJP_00148 4.3e-109 capA M Bacterial capsule synthesis protein
AFANOAJP_00149 1.5e-55 capA M Bacterial capsule synthesis protein
AFANOAJP_00150 3.6e-39 gcvR T UPF0237 protein
AFANOAJP_00151 1.7e-243 XK27_08635 S UPF0210 protein
AFANOAJP_00152 2.4e-135 ais G Phosphoglycerate mutase
AFANOAJP_00153 7.9e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
AFANOAJP_00154 1.5e-101 acmA 3.2.1.17 NU amidase activity
AFANOAJP_00155 1.1e-13 L Transposase
AFANOAJP_00156 1.4e-73 L Transposase
AFANOAJP_00157 2.2e-29
AFANOAJP_00158 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AFANOAJP_00159 5.3e-70 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AFANOAJP_00160 2.3e-294 dnaK O Heat shock 70 kDa protein
AFANOAJP_00161 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AFANOAJP_00162 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AFANOAJP_00163 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
AFANOAJP_00164 3.8e-31 hmpT S membrane
AFANOAJP_00177 1.9e-250 L Transposase
AFANOAJP_00178 2.8e-52 amd 3.5.1.47 E Peptidase dimerisation domain
AFANOAJP_00179 2.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
AFANOAJP_00180 6.5e-87
AFANOAJP_00181 1.6e-77 sigH K DNA-templated transcription, initiation
AFANOAJP_00182 3e-148 ykuT M mechanosensitive ion channel
AFANOAJP_00183 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AFANOAJP_00184 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AFANOAJP_00185 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AFANOAJP_00186 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
AFANOAJP_00187 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
AFANOAJP_00188 2e-177 prmA J Ribosomal protein L11 methyltransferase
AFANOAJP_00189 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AFANOAJP_00190 1.2e-13 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
AFANOAJP_00191 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
AFANOAJP_00192 1.8e-83 nrdI F Belongs to the NrdI family
AFANOAJP_00193 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AFANOAJP_00194 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AFANOAJP_00195 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AFANOAJP_00196 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AFANOAJP_00197 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AFANOAJP_00198 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AFANOAJP_00199 3.9e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AFANOAJP_00200 1.1e-110 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AFANOAJP_00201 2.9e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
AFANOAJP_00202 6.5e-202 yhjX P Major Facilitator
AFANOAJP_00203 1.3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AFANOAJP_00204 5e-94 V VanZ like family
AFANOAJP_00206 1e-123 glnQ E abc transporter atp-binding protein
AFANOAJP_00207 1.8e-276 glnP P ABC transporter
AFANOAJP_00208 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AFANOAJP_00209 1.5e-135 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AFANOAJP_00210 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
AFANOAJP_00211 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
AFANOAJP_00212 6.3e-235 sufD O assembly protein SufD
AFANOAJP_00213 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AFANOAJP_00214 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
AFANOAJP_00215 3.5e-274 sufB O assembly protein SufB
AFANOAJP_00216 1.9e-178 oppA E ABC transporter substrate-binding protein
AFANOAJP_00217 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFANOAJP_00218 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFANOAJP_00219 5.3e-72 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFANOAJP_00220 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFANOAJP_00221 8e-28 oppD P Belongs to the ABC transporter superfamily
AFANOAJP_00222 2.5e-32 oppD P Belongs to the ABC transporter superfamily
AFANOAJP_00223 4.8e-67 oppD P Belongs to the ABC transporter superfamily
AFANOAJP_00224 1.7e-30 oppD P Belongs to the ABC transporter superfamily
AFANOAJP_00225 9e-170 oppF P Belongs to the ABC transporter superfamily
AFANOAJP_00228 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AFANOAJP_00229 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFANOAJP_00230 1.9e-223 EGP Major facilitator Superfamily
AFANOAJP_00231 3.1e-72 adcR K transcriptional
AFANOAJP_00232 2.2e-136 adcC P ABC transporter, ATP-binding protein
AFANOAJP_00233 4.6e-130 adcB P ABC transporter (Permease
AFANOAJP_00234 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
AFANOAJP_00235 6.9e-28 ptsG 2.7.1.199, 2.7.1.208 G pts system
AFANOAJP_00236 5.1e-149 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
AFANOAJP_00237 8.3e-82 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AFANOAJP_00238 1.6e-148 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
AFANOAJP_00239 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
AFANOAJP_00240 1.9e-127 yeeN K transcriptional regulatory protein
AFANOAJP_00241 9.8e-50 yajC U protein transport
AFANOAJP_00242 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AFANOAJP_00243 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
AFANOAJP_00244 5.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AFANOAJP_00245 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AFANOAJP_00246 0.0 WQ51_06230 S ABC transporter substrate binding protein
AFANOAJP_00247 5.2e-142 cmpC S abc transporter atp-binding protein
AFANOAJP_00248 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AFANOAJP_00249 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AFANOAJP_00250 4.4e-37 L Transposase
AFANOAJP_00251 6.4e-18 L transposase activity
AFANOAJP_00252 1.5e-30 L transposition
AFANOAJP_00255 4.7e-43
AFANOAJP_00256 3.4e-55 S TM2 domain
AFANOAJP_00257 1.8e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFANOAJP_00258 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFANOAJP_00259 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AFANOAJP_00260 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
AFANOAJP_00261 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
AFANOAJP_00262 7.8e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
AFANOAJP_00263 6e-55 cof Q phosphatase activity
AFANOAJP_00264 1.1e-34 cof Q phosphatase activity
AFANOAJP_00265 3.1e-136 glcR K transcriptional regulator (DeoR family)
AFANOAJP_00266 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFANOAJP_00268 3.8e-40 K transcriptional
AFANOAJP_00270 2.6e-76 S thiolester hydrolase activity
AFANOAJP_00271 3.7e-137 S COG1073 Hydrolases of the alpha beta superfamily
AFANOAJP_00272 8.2e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AFANOAJP_00273 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AFANOAJP_00274 1e-75 yhaI L Membrane
AFANOAJP_00275 5.1e-259 pepC 3.4.22.40 E aminopeptidase
AFANOAJP_00276 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFANOAJP_00277 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AFANOAJP_00278 1.3e-93 ypsA S Belongs to the UPF0398 family
AFANOAJP_00279 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AFANOAJP_00280 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AFANOAJP_00281 1.9e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
AFANOAJP_00282 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
AFANOAJP_00283 2.5e-23
AFANOAJP_00284 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AFANOAJP_00285 3.3e-250 L Transposase
AFANOAJP_00286 3.1e-20 XK27_09675 K -acetyltransferase
AFANOAJP_00287 9.3e-46 XK27_09675 K -acetyltransferase
AFANOAJP_00288 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AFANOAJP_00289 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AFANOAJP_00291 3.7e-82 L Integrase core domain protein
AFANOAJP_00292 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFANOAJP_00293 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AFANOAJP_00294 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFANOAJP_00295 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
AFANOAJP_00296 1.5e-97 ybhL S Belongs to the BI1 family
AFANOAJP_00297 3.6e-114 L Transposase
AFANOAJP_00298 1.2e-109 L Transposase
AFANOAJP_00301 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AFANOAJP_00302 8.1e-91 K transcriptional regulator
AFANOAJP_00303 7.6e-36 yneF S UPF0154 protein
AFANOAJP_00304 4.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AFANOAJP_00305 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AFANOAJP_00306 3.5e-99 XK27_09740 S Phosphoesterase
AFANOAJP_00307 7.8e-85 ykuL S CBS domain
AFANOAJP_00308 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
AFANOAJP_00309 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AFANOAJP_00310 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AFANOAJP_00311 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFANOAJP_00312 8e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AFANOAJP_00313 1.3e-257 trkH P Cation transport protein
AFANOAJP_00314 1.8e-248 trkA P Potassium transporter peripheral membrane component
AFANOAJP_00315 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AFANOAJP_00316 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AFANOAJP_00317 9.1e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
AFANOAJP_00318 5.6e-161 K sequence-specific DNA binding
AFANOAJP_00319 1.2e-32 V protein secretion by the type I secretion system
AFANOAJP_00320 1.4e-108 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AFANOAJP_00321 1.1e-34 V protein secretion by the type I secretion system
AFANOAJP_00322 1.8e-27 comA V protein secretion by the type I secretion system
AFANOAJP_00323 5.4e-66 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AFANOAJP_00324 6e-46 yhaI L Membrane
AFANOAJP_00325 9.2e-132 S Domain of unknown function (DUF4173)
AFANOAJP_00326 6.8e-95 ureI S AmiS/UreI family transporter
AFANOAJP_00327 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
AFANOAJP_00328 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
AFANOAJP_00329 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
AFANOAJP_00330 2.5e-77 ureE O enzyme active site formation
AFANOAJP_00331 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AFANOAJP_00332 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AFANOAJP_00333 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AFANOAJP_00334 2.7e-177 cbiM P PDGLE domain
AFANOAJP_00335 1.7e-137 P cobalt transport protein
AFANOAJP_00336 1.6e-131 cbiO P ABC transporter
AFANOAJP_00337 1.8e-153 ET amino acid transport
AFANOAJP_00338 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFANOAJP_00339 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
AFANOAJP_00340 5.5e-204 EGP Transmembrane secretion effector
AFANOAJP_00341 1.8e-153 ET amino acid transport
AFANOAJP_00342 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
AFANOAJP_00343 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
AFANOAJP_00344 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
AFANOAJP_00345 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
AFANOAJP_00346 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFANOAJP_00347 5.2e-98 metI P ABC transporter (Permease
AFANOAJP_00348 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AFANOAJP_00349 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
AFANOAJP_00350 8e-94 S UPF0397 protein
AFANOAJP_00351 0.0 ykoD P abc transporter atp-binding protein
AFANOAJP_00352 1.2e-149 cbiQ P cobalt transport
AFANOAJP_00353 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AFANOAJP_00354 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
AFANOAJP_00355 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
AFANOAJP_00356 7.5e-242 P COG0168 Trk-type K transport systems, membrane components
AFANOAJP_00357 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
AFANOAJP_00358 8.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
AFANOAJP_00359 3.9e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFANOAJP_00360 3e-276 T PhoQ Sensor
AFANOAJP_00361 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AFANOAJP_00362 1.4e-217 dnaB L Replication initiation and membrane attachment
AFANOAJP_00363 4.4e-166 dnaI L Primosomal protein DnaI
AFANOAJP_00364 5.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AFANOAJP_00365 5.1e-27 L Integrase core domain protein
AFANOAJP_00366 3.4e-50 L transposition
AFANOAJP_00367 5.7e-23 L Transposase
AFANOAJP_00368 1.2e-40 L transposase activity
AFANOAJP_00369 1.5e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AFANOAJP_00370 6.5e-63 manO S protein conserved in bacteria
AFANOAJP_00371 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
AFANOAJP_00372 1.7e-116 manM G pts system
AFANOAJP_00373 1.1e-181 manL 2.7.1.191 G pts system
AFANOAJP_00374 7.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
AFANOAJP_00375 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
AFANOAJP_00376 1.9e-248 pbuO S permease
AFANOAJP_00377 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
AFANOAJP_00378 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
AFANOAJP_00379 2.5e-220 brpA K Transcriptional
AFANOAJP_00380 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
AFANOAJP_00381 3.1e-212 nusA K Participates in both transcription termination and antitermination
AFANOAJP_00382 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
AFANOAJP_00383 1.4e-41 ylxQ J ribosomal protein
AFANOAJP_00384 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AFANOAJP_00385 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AFANOAJP_00386 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
AFANOAJP_00387 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
AFANOAJP_00388 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
AFANOAJP_00389 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
AFANOAJP_00390 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AFANOAJP_00391 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
AFANOAJP_00392 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
AFANOAJP_00393 5.8e-52 metB 2.5.1.48, 4.4.1.8 E cystathionine
AFANOAJP_00394 9.3e-127 metB 2.5.1.48, 4.4.1.8 E cystathionine
AFANOAJP_00395 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
AFANOAJP_00396 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
AFANOAJP_00397 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AFANOAJP_00398 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AFANOAJP_00399 7.5e-74 ylbF S Belongs to the UPF0342 family
AFANOAJP_00400 7.1e-46 ylbG S UPF0298 protein
AFANOAJP_00401 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
AFANOAJP_00402 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
AFANOAJP_00403 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
AFANOAJP_00404 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
AFANOAJP_00405 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
AFANOAJP_00406 2.8e-70 acuB S IMP dehydrogenase activity
AFANOAJP_00407 3.3e-43 acuB S IMP dehydrogenase activity
AFANOAJP_00408 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFANOAJP_00409 6.3e-111 yvyE 3.4.13.9 S YigZ family
AFANOAJP_00410 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AFANOAJP_00411 9.9e-123 comFC S Competence protein
AFANOAJP_00412 2.2e-91 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AFANOAJP_00420 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
AFANOAJP_00421 6.4e-108 S Domain of unknown function (DUF1803)
AFANOAJP_00422 1.3e-101 ygaC J Belongs to the UPF0374 family
AFANOAJP_00423 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
AFANOAJP_00424 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFANOAJP_00425 2.3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
AFANOAJP_00426 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
AFANOAJP_00427 1.9e-115 S Haloacid dehalogenase-like hydrolase
AFANOAJP_00428 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
AFANOAJP_00429 4e-72 marR K Transcriptional regulator, MarR family
AFANOAJP_00430 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFANOAJP_00431 4.8e-29 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFANOAJP_00432 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
AFANOAJP_00433 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
AFANOAJP_00434 1.6e-126 IQ reductase
AFANOAJP_00435 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFANOAJP_00436 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AFANOAJP_00437 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AFANOAJP_00438 7.5e-258 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
AFANOAJP_00439 4.1e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AFANOAJP_00440 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
AFANOAJP_00441 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AFANOAJP_00442 1.1e-202 rny D Endoribonuclease that initiates mRNA decay
AFANOAJP_00443 1.8e-84 L Transposase
AFANOAJP_00444 1.2e-113 fruR K transcriptional
AFANOAJP_00445 8.4e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AFANOAJP_00446 0.0 fruA 2.7.1.202 G phosphotransferase system
AFANOAJP_00447 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AFANOAJP_00448 6.2e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AFANOAJP_00450 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
AFANOAJP_00451 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AFANOAJP_00452 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AFANOAJP_00453 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
AFANOAJP_00454 6.4e-29 2.3.1.128 K acetyltransferase
AFANOAJP_00455 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
AFANOAJP_00456 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AFANOAJP_00457 5e-133 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AFANOAJP_00458 2.6e-64 WQ51_03320 S cog cog4835
AFANOAJP_00459 6.4e-61 XK27_08360 S EDD domain protein, DegV family
AFANOAJP_00460 5.5e-75 XK27_08360 S EDD domain protein, DegV family
AFANOAJP_00461 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AFANOAJP_00462 1.2e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AFANOAJP_00463 0.0 yfmR S abc transporter atp-binding protein
AFANOAJP_00464 3.3e-25 U response to pH
AFANOAJP_00465 1e-139 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
AFANOAJP_00466 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
AFANOAJP_00467 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
AFANOAJP_00468 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
AFANOAJP_00469 1.9e-77 K DNA-binding transcription factor activity
AFANOAJP_00470 0.0 lmrA1 V abc transporter atp-binding protein
AFANOAJP_00471 0.0 lmrA2 V abc transporter atp-binding protein
AFANOAJP_00472 2.2e-18 K Acetyltransferase (GNAT) family
AFANOAJP_00473 3.2e-78 sptS 2.7.13.3 T Histidine kinase
AFANOAJP_00474 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AFANOAJP_00475 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AFANOAJP_00476 5.3e-161 cvfB S Protein conserved in bacteria
AFANOAJP_00477 1.6e-34 yozE S Belongs to the UPF0346 family
AFANOAJP_00478 5.5e-120 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
AFANOAJP_00479 1.5e-60 rlpA M LysM domain protein
AFANOAJP_00480 1.5e-189 phoH T phosphate starvation-inducible protein PhoH
AFANOAJP_00484 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFANOAJP_00485 1.8e-164 K transcriptional regulator (lysR family)
AFANOAJP_00486 1.4e-186 coiA 3.6.4.12 S Competence protein
AFANOAJP_00487 0.0 pepF E oligoendopeptidase F
AFANOAJP_00488 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
AFANOAJP_00489 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
AFANOAJP_00490 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AFANOAJP_00491 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
AFANOAJP_00492 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
AFANOAJP_00493 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
AFANOAJP_00494 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AFANOAJP_00495 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
AFANOAJP_00496 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AFANOAJP_00497 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AFANOAJP_00498 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
AFANOAJP_00499 1.4e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
AFANOAJP_00500 2.2e-130 yxkH G deacetylase
AFANOAJP_00501 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AFANOAJP_00502 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AFANOAJP_00503 5.5e-153 rarD S Transporter
AFANOAJP_00504 2.2e-15 T peptidase
AFANOAJP_00505 8.9e-14 coiA 3.6.4.12 S Competence protein
AFANOAJP_00506 6.3e-113 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AFANOAJP_00507 8.3e-75 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AFANOAJP_00508 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AFANOAJP_00509 9.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFANOAJP_00510 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
AFANOAJP_00511 3.3e-78 atpF C ATP synthase F(0) sector subunit b
AFANOAJP_00512 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFANOAJP_00513 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AFANOAJP_00514 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AFANOAJP_00515 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AFANOAJP_00516 2e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AFANOAJP_00517 1.4e-226 ftsW D Belongs to the SEDS family
AFANOAJP_00518 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AFANOAJP_00519 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AFANOAJP_00520 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AFANOAJP_00521 2.4e-161 holB 2.7.7.7 L dna polymerase iii
AFANOAJP_00522 3.1e-134 yaaT S stage 0 sporulation protein
AFANOAJP_00523 9.5e-55 yabA L Involved in initiation control of chromosome replication
AFANOAJP_00524 3.5e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AFANOAJP_00525 5.8e-233 amt P Ammonium Transporter
AFANOAJP_00526 1.1e-53 glnB K Belongs to the P(II) protein family
AFANOAJP_00527 4.9e-106 mur1 NU mannosyl-glycoprotein
AFANOAJP_00528 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
AFANOAJP_00529 1.2e-92 nptA P COG1283 Na phosphate symporter
AFANOAJP_00530 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AFANOAJP_00531 4.9e-51
AFANOAJP_00532 2.2e-25
AFANOAJP_00533 1.1e-59
AFANOAJP_00534 6.1e-63 S membrane
AFANOAJP_00535 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AFANOAJP_00536 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AFANOAJP_00537 4.5e-39 ynzC S UPF0291 protein
AFANOAJP_00538 2.3e-254 cycA E permease
AFANOAJP_00539 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
AFANOAJP_00540 5.8e-71 pts33BCA G pts system
AFANOAJP_00541 2.6e-95 pts33BCA G pts system
AFANOAJP_00542 1.5e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
AFANOAJP_00543 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AFANOAJP_00544 1.2e-165 L integrase core domain
AFANOAJP_00545 6.7e-122 L Transposase
AFANOAJP_00550 1.5e-166 fhuR K transcriptional regulator (lysR family)
AFANOAJP_00551 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AFANOAJP_00552 8.5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFANOAJP_00553 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AFANOAJP_00554 4.9e-227 pyrP F uracil Permease
AFANOAJP_00555 2.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AFANOAJP_00556 6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
AFANOAJP_00557 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
AFANOAJP_00558 3.4e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
AFANOAJP_00559 2.9e-10 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFANOAJP_00560 3.6e-35 V efflux transmembrane transporter activity
AFANOAJP_00561 3.1e-31 V efflux transmembrane transporter activity
AFANOAJP_00562 8.2e-28 ytrF V efflux transmembrane transporter activity
AFANOAJP_00563 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AFANOAJP_00564 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AFANOAJP_00565 3.4e-77 L Transposase
AFANOAJP_00566 3.7e-146 L Transposase
AFANOAJP_00567 1.6e-18 L Integrase core domain
AFANOAJP_00568 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
AFANOAJP_00569 2.8e-164 hrtB V MacB-like periplasmic core domain
AFANOAJP_00572 3e-92 S MucBP domain
AFANOAJP_00573 5.9e-51 M YSIRK type signal peptide
AFANOAJP_00574 0.0 M the current gene model (or a revised gene model) may contain a
AFANOAJP_00576 0.0 mdlB V abc transporter atp-binding protein
AFANOAJP_00577 0.0 lmrA V abc transporter atp-binding protein
AFANOAJP_00578 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AFANOAJP_00579 2.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AFANOAJP_00580 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
AFANOAJP_00581 2.5e-132 rr02 KT response regulator
AFANOAJP_00582 3.5e-213 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AFANOAJP_00583 2.8e-168 V ABC transporter
AFANOAJP_00584 5.4e-122 sagI S ABC-2 type transporter
AFANOAJP_00585 2.4e-197 yceA S Belongs to the UPF0176 family
AFANOAJP_00586 8e-28 XK27_00085 K Transcriptional
AFANOAJP_00587 1.1e-22
AFANOAJP_00588 6.5e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
AFANOAJP_00589 9.6e-113 S VIT family
AFANOAJP_00590 3.3e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFANOAJP_00591 7.5e-219 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
AFANOAJP_00592 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
AFANOAJP_00593 1e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
AFANOAJP_00594 4.4e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AFANOAJP_00595 2.4e-07 ytjP 3.5.1.18 E Dipeptidase
AFANOAJP_00596 3.2e-97 ET Bacterial extracellular solute-binding proteins, family 3
AFANOAJP_00597 1.9e-59 K Acetyltransferase (GNAT) domain
AFANOAJP_00599 7.3e-151 1.8.5.7 O Glutathione S-transferase
AFANOAJP_00600 2.6e-170 1.8.5.7 O Glutathione S-transferase, C-terminal domain
AFANOAJP_00601 1.3e-138 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
AFANOAJP_00602 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AFANOAJP_00603 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
AFANOAJP_00604 1.5e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AFANOAJP_00605 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AFANOAJP_00606 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
AFANOAJP_00607 2.5e-21
AFANOAJP_00608 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AFANOAJP_00610 3.5e-07 U protein secretion
AFANOAJP_00611 2.1e-50 U protein secretion
AFANOAJP_00612 1.1e-11 U protein secretion
AFANOAJP_00613 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
AFANOAJP_00614 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
AFANOAJP_00615 5.5e-49 XK27_13030
AFANOAJP_00616 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFANOAJP_00617 1.6e-86 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AFANOAJP_00618 1.4e-69 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AFANOAJP_00619 6.1e-165 S Protein of unknown function (DUF3114)
AFANOAJP_00620 1.2e-22 S Protein of unknown function (DUF3114)
AFANOAJP_00621 1.5e-118 yqfA K protein, Hemolysin III
AFANOAJP_00622 3.6e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
AFANOAJP_00623 1.7e-218 mvaS 2.3.3.10 I synthase
AFANOAJP_00624 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFANOAJP_00625 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AFANOAJP_00626 9.7e-22
AFANOAJP_00627 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AFANOAJP_00628 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
AFANOAJP_00629 1.3e-249 mmuP E amino acid
AFANOAJP_00630 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
AFANOAJP_00631 1.4e-29 S Domain of unknown function (DUF1912)
AFANOAJP_00632 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
AFANOAJP_00633 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AFANOAJP_00634 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFANOAJP_00635 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFANOAJP_00636 6.9e-200 ilvE 2.6.1.42 E Aminotransferase
AFANOAJP_00637 4.8e-16 S Protein of unknown function (DUF2969)
AFANOAJP_00640 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
AFANOAJP_00643 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
AFANOAJP_00644 6.1e-70 M Pfam SNARE associated Golgi protein
AFANOAJP_00645 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
AFANOAJP_00646 9.3e-59 S oxidoreductase
AFANOAJP_00647 9.7e-66 S oxidoreductase
AFANOAJP_00648 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
AFANOAJP_00649 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
AFANOAJP_00650 0.0 clpE O Belongs to the ClpA ClpB family
AFANOAJP_00651 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AFANOAJP_00652 1.3e-34 ykuJ S protein conserved in bacteria
AFANOAJP_00653 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
AFANOAJP_00654 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
AFANOAJP_00655 1.1e-78 feoA P FeoA domain protein
AFANOAJP_00656 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
AFANOAJP_00657 1.5e-07
AFANOAJP_00658 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AFANOAJP_00659 2.2e-45 K sequence-specific DNA binding
AFANOAJP_00660 2.5e-33 yugF I carboxylic ester hydrolase activity
AFANOAJP_00661 7.5e-23 I Alpha/beta hydrolase family
AFANOAJP_00662 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AFANOAJP_00663 3.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AFANOAJP_00664 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
AFANOAJP_00665 8.4e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AFANOAJP_00666 8.4e-63 licT K transcriptional antiterminator
AFANOAJP_00667 6.8e-53 licT K transcriptional antiterminator
AFANOAJP_00668 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AFANOAJP_00669 8.3e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
AFANOAJP_00670 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AFANOAJP_00671 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AFANOAJP_00672 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AFANOAJP_00673 8.4e-31 mdtG EGP Major facilitator Superfamily
AFANOAJP_00674 5e-157 mdtG EGP Major facilitator Superfamily
AFANOAJP_00675 2e-33 secG U Preprotein translocase subunit SecG
AFANOAJP_00676 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AFANOAJP_00677 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AFANOAJP_00678 5.3e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AFANOAJP_00679 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
AFANOAJP_00680 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
AFANOAJP_00681 4.4e-183 ccpA K Catabolite control protein A
AFANOAJP_00682 2.8e-28 yyaQ S YjbR
AFANOAJP_00683 6.6e-101 yyaQ V Protein conserved in bacteria
AFANOAJP_00684 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AFANOAJP_00685 2.5e-77 yueI S Protein of unknown function (DUF1694)
AFANOAJP_00686 1.3e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AFANOAJP_00688 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AFANOAJP_00689 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
AFANOAJP_00690 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AFANOAJP_00691 4.1e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFANOAJP_00692 6.5e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AFANOAJP_00693 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AFANOAJP_00694 2.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
AFANOAJP_00695 3.2e-53 yheA S Belongs to the UPF0342 family
AFANOAJP_00696 8.8e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
AFANOAJP_00697 8.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AFANOAJP_00698 2.5e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AFANOAJP_00699 3.9e-153 pheA 4.2.1.51 E Prephenate dehydratase
AFANOAJP_00700 1.1e-251 msrR K Transcriptional regulator
AFANOAJP_00701 1.8e-237 L Transposase
AFANOAJP_00702 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
AFANOAJP_00703 4.1e-203 I acyl-CoA dehydrogenase
AFANOAJP_00704 4.5e-97 mip S hydroperoxide reductase activity
AFANOAJP_00705 2.2e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFANOAJP_00706 8.9e-20
AFANOAJP_00707 3.2e-46
AFANOAJP_00708 1.5e-18 K Cro/C1-type HTH DNA-binding domain
AFANOAJP_00709 1.5e-44 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
AFANOAJP_00710 9.5e-28 estA E GDSL-like Lipase/Acylhydrolase
AFANOAJP_00711 1.1e-94
AFANOAJP_00712 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AFANOAJP_00713 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AFANOAJP_00714 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AFANOAJP_00715 3.7e-188 S CRISPR-associated protein Csn2 subfamily St
AFANOAJP_00716 2.4e-147 ycgQ S TIGR03943 family
AFANOAJP_00717 1.3e-154 XK27_03015 S permease
AFANOAJP_00719 0.0 yhgF K Transcriptional accessory protein
AFANOAJP_00720 9.9e-42 pspC KT PspC domain
AFANOAJP_00721 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AFANOAJP_00722 2.6e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AFANOAJP_00724 1e-67 ytxH S General stress protein
AFANOAJP_00726 1.2e-177 yegQ O Peptidase U32
AFANOAJP_00727 3.4e-252 yegQ O Peptidase U32
AFANOAJP_00728 4.5e-89 bioY S biotin synthase
AFANOAJP_00730 1.1e-33 XK27_12190 S protein conserved in bacteria
AFANOAJP_00731 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
AFANOAJP_00732 4.3e-12
AFANOAJP_00733 3.1e-68 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
AFANOAJP_00734 0.0 L helicase
AFANOAJP_00735 6.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AFANOAJP_00736 1e-163 M LysM domain
AFANOAJP_00737 1.7e-15
AFANOAJP_00738 2.3e-175 S hydrolase
AFANOAJP_00739 9e-113 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
AFANOAJP_00740 8.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AFANOAJP_00741 6.7e-149 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
AFANOAJP_00742 2.7e-27 P Hemerythrin HHE cation binding domain protein
AFANOAJP_00743 5.2e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFANOAJP_00744 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
AFANOAJP_00745 9.1e-27 MA20_36090 S Protein of unknown function (DUF2974)
AFANOAJP_00746 1.8e-128 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AFANOAJP_00747 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
AFANOAJP_00748 2.1e-109
AFANOAJP_00749 4.2e-221 S SIR2-like domain
AFANOAJP_00750 1.5e-276 S Domain of unknown function DUF87
AFANOAJP_00751 2.5e-127 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
AFANOAJP_00752 1e-42 K Helix-turn-helix domain
AFANOAJP_00753 1.4e-303 hsdM 2.1.1.72 V type I restriction-modification system
AFANOAJP_00754 1.1e-90 S double-stranded DNA endodeoxyribonuclease activity
AFANOAJP_00755 1.4e-148 spd F DNA RNA non-specific endonuclease
AFANOAJP_00756 1.7e-91 lemA S LemA family
AFANOAJP_00757 2.1e-131 htpX O Belongs to the peptidase M48B family
AFANOAJP_00758 3e-73 S Psort location CytoplasmicMembrane, score
AFANOAJP_00759 6.2e-56 S Domain of unknown function (DUF4430)
AFANOAJP_00760 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AFANOAJP_00761 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
AFANOAJP_00762 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
AFANOAJP_00763 1.1e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
AFANOAJP_00764 3.3e-250 L Transposase
AFANOAJP_00765 1.8e-113 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
AFANOAJP_00766 3.5e-91 dps P Belongs to the Dps family
AFANOAJP_00767 1.1e-80 perR P Belongs to the Fur family
AFANOAJP_00768 8.4e-28 yqgQ S protein conserved in bacteria
AFANOAJP_00769 2.2e-179 glk 2.7.1.2 G Glucokinase
AFANOAJP_00770 0.0 typA T GTP-binding protein TypA
AFANOAJP_00772 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AFANOAJP_00773 2.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AFANOAJP_00774 2.9e-175 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AFANOAJP_00775 2.3e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AFANOAJP_00776 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFANOAJP_00777 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AFANOAJP_00778 1.4e-96 sepF D cell septum assembly
AFANOAJP_00779 2e-34 yggT D integral membrane protein
AFANOAJP_00780 4e-142 ylmH T S4 RNA-binding domain
AFANOAJP_00781 1.8e-135 divIVA D Cell division protein DivIVA
AFANOAJP_00782 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AFANOAJP_00783 3.8e-16
AFANOAJP_00784 4.6e-38
AFANOAJP_00785 8.4e-10
AFANOAJP_00786 2.1e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
AFANOAJP_00787 2e-45 rpmE2 J 50S ribosomal protein L31
AFANOAJP_00788 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AFANOAJP_00789 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
AFANOAJP_00790 6.8e-155 gst O Glutathione S-transferase
AFANOAJP_00791 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AFANOAJP_00792 4.5e-111 tdk 2.7.1.21 F thymidine kinase
AFANOAJP_00793 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AFANOAJP_00794 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AFANOAJP_00795 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AFANOAJP_00796 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AFANOAJP_00797 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
AFANOAJP_00798 6.6e-105 pvaA M lytic transglycosylase activity
AFANOAJP_00799 0.0 yfiB1 V abc transporter atp-binding protein
AFANOAJP_00800 0.0 XK27_10035 V abc transporter atp-binding protein
AFANOAJP_00801 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
AFANOAJP_00802 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFANOAJP_00803 3.9e-237 dltB M Membrane protein involved in D-alanine export
AFANOAJP_00804 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFANOAJP_00805 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AFANOAJP_00806 6.3e-34 L Integrase core domain protein
AFANOAJP_00807 9.6e-32 L transposition
AFANOAJP_00808 6.5e-54 L transposition
AFANOAJP_00809 7.7e-19 L transposase activity
AFANOAJP_00810 2.5e-40 L Transposase
AFANOAJP_00811 0.0 3.6.3.8 P cation transport ATPase
AFANOAJP_00812 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
AFANOAJP_00814 3e-44 ymbI L transposase activity
AFANOAJP_00815 4e-22 L Belongs to the 'phage' integrase family
AFANOAJP_00816 1.4e-66 S tRNA_anti-like
AFANOAJP_00817 2e-103
AFANOAJP_00819 5e-12
AFANOAJP_00821 2e-296 S DNA primase
AFANOAJP_00822 3e-164 KL Phage plasmid primase P4 family
AFANOAJP_00823 6.9e-22
AFANOAJP_00824 9.2e-13
AFANOAJP_00829 1.3e-17 K Cro/C1-type HTH DNA-binding domain
AFANOAJP_00831 1.1e-220 sip L Belongs to the 'phage' integrase family
AFANOAJP_00833 1.2e-165 L integrase core domain
AFANOAJP_00834 6.7e-122 L Helix-turn-helix domain
AFANOAJP_00835 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AFANOAJP_00836 1.6e-165 metF 1.5.1.20 E reductase
AFANOAJP_00837 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
AFANOAJP_00838 1.7e-94 panT S ECF transporter, substrate-specific component
AFANOAJP_00839 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AFANOAJP_00840 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
AFANOAJP_00841 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AFANOAJP_00842 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFANOAJP_00843 2.8e-40 T PhoQ Sensor
AFANOAJP_00844 1.7e-43 T PhoQ Sensor
AFANOAJP_00845 5.8e-79 T PhoQ Sensor
AFANOAJP_00846 6.7e-122 L Helix-turn-helix domain
AFANOAJP_00847 1.2e-165 L integrase core domain
AFANOAJP_00848 1e-190 L Transposase
AFANOAJP_00849 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
AFANOAJP_00850 8.9e-206 potD P spermidine putrescine ABC transporter
AFANOAJP_00851 3.1e-268 clcA P Chloride transporter, ClC family
AFANOAJP_00852 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
AFANOAJP_00853 3.5e-103 L Helix-turn-helix domain
AFANOAJP_00854 5.6e-166 L Integrase core domain protein
AFANOAJP_00855 8e-249 L Transposase
AFANOAJP_00856 1e-29 rpsT J rRNA binding
AFANOAJP_00857 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
AFANOAJP_00858 8.3e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
AFANOAJP_00859 6.9e-26 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
AFANOAJP_00860 1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
AFANOAJP_00861 1.9e-99 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
AFANOAJP_00862 6e-21 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AFANOAJP_00863 2e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AFANOAJP_00864 3.7e-54 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
AFANOAJP_00865 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
AFANOAJP_00866 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
AFANOAJP_00867 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
AFANOAJP_00868 1e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
AFANOAJP_00869 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
AFANOAJP_00870 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AFANOAJP_00871 3.1e-81 ypmB S Protein conserved in bacteria
AFANOAJP_00872 3e-215 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AFANOAJP_00873 6.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AFANOAJP_00875 1.4e-07
AFANOAJP_00876 6.3e-23
AFANOAJP_00877 3e-13
AFANOAJP_00878 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
AFANOAJP_00879 9.8e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AFANOAJP_00880 5.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
AFANOAJP_00881 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
AFANOAJP_00882 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
AFANOAJP_00883 7.3e-20 D nuclear chromosome segregation
AFANOAJP_00884 7.4e-138 yejC S cyclic nucleotide-binding protein
AFANOAJP_00885 1.2e-163 rapZ S Displays ATPase and GTPase activities
AFANOAJP_00886 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AFANOAJP_00887 8.7e-162 whiA K May be required for sporulation
AFANOAJP_00888 1.2e-103 pepD E Dipeptidase
AFANOAJP_00889 2.6e-44 pepD E Dipeptidase
AFANOAJP_00890 1.5e-75 tspO T TspO/MBR family
AFANOAJP_00891 1.9e-59 S Uncharacterised lipoprotein family
AFANOAJP_00892 3e-187 L Transposase
AFANOAJP_00893 1.9e-121 tnp L DDE domain
AFANOAJP_00894 2.8e-48 S Protein of unknown function with HXXEE motif
AFANOAJP_00895 2.1e-96 tnp L DDE domain
AFANOAJP_00896 7.1e-28 L transposase activity
AFANOAJP_00898 2.4e-27
AFANOAJP_00899 9.3e-32 cspD K Cold shock protein domain
AFANOAJP_00900 8e-42 K Cold-Shock Protein
AFANOAJP_00901 3.3e-250 L Transposase
AFANOAJP_00902 8.1e-32 L Transposase
AFANOAJP_00903 3.5e-177 L Transposase
AFANOAJP_00904 0.0 copB 3.6.3.4 P P-type ATPase
AFANOAJP_00905 2.4e-68 L Transposase
AFANOAJP_00906 6.3e-54 L Transposase
AFANOAJP_00907 1.6e-188 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
AFANOAJP_00908 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFANOAJP_00909 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AFANOAJP_00910 1.5e-59 cysE 2.3.1.30 E serine acetyltransferase
AFANOAJP_00911 3.2e-31 L Transposase
AFANOAJP_00912 5.4e-181 L Transposase
AFANOAJP_00913 3.9e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
AFANOAJP_00914 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
AFANOAJP_00915 3.7e-157 glcU U Glucose uptake
AFANOAJP_00916 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
AFANOAJP_00917 2.6e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
AFANOAJP_00918 2.2e-101 XK27_10720 D peptidase activity
AFANOAJP_00919 9.2e-297 adcA P Belongs to the bacterial solute-binding protein 9 family
AFANOAJP_00920 1.7e-08
AFANOAJP_00922 1.2e-172 yeiH S Membrane
AFANOAJP_00923 5.1e-117 mur1 NU muramidase
AFANOAJP_00924 3.2e-35 L transposase activity
AFANOAJP_00925 4.5e-166 cpsY K Transcriptional regulator
AFANOAJP_00926 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AFANOAJP_00927 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
AFANOAJP_00928 2.4e-105 artQ P ABC transporter (Permease
AFANOAJP_00929 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
AFANOAJP_00930 1.1e-158 aatB ET ABC transporter substrate-binding protein
AFANOAJP_00931 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFANOAJP_00932 2.1e-07
AFANOAJP_00933 8e-58 adhP 1.1.1.1 C alcohol dehydrogenase
AFANOAJP_00934 7.9e-112 adhP 1.1.1.1 C alcohol dehydrogenase
AFANOAJP_00935 8.3e-49 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
AFANOAJP_00936 3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AFANOAJP_00937 2.9e-125 gntR1 K transcriptional
AFANOAJP_00938 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AFANOAJP_00939 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AFANOAJP_00940 2.4e-87 niaX
AFANOAJP_00941 6e-91 niaR S small molecule binding protein (contains 3H domain)
AFANOAJP_00942 8.1e-128 K DNA-binding helix-turn-helix protein
AFANOAJP_00943 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AFANOAJP_00944 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFANOAJP_00945 4.1e-167 GK ROK family
AFANOAJP_00946 8.3e-159 dprA LU DNA protecting protein DprA
AFANOAJP_00947 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFANOAJP_00948 1.3e-151 S TraX protein
AFANOAJP_00949 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFANOAJP_00950 5.3e-251 T PhoQ Sensor
AFANOAJP_00951 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AFANOAJP_00952 3.2e-152 XK27_05470 E Methionine synthase
AFANOAJP_00953 7.5e-21 XK27_05470 E Methionine synthase
AFANOAJP_00954 5e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
AFANOAJP_00955 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AFANOAJP_00956 1.3e-49 IQ Acetoin reductase
AFANOAJP_00957 9.1e-46 IQ Acetoin reductase
AFANOAJP_00959 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AFANOAJP_00960 1.3e-154 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AFANOAJP_00963 1.1e-212 pqqE C radical SAM domain protein
AFANOAJP_00964 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
AFANOAJP_00965 6.6e-61 EGP Major facilitator Superfamily
AFANOAJP_00966 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
AFANOAJP_00967 5.1e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
AFANOAJP_00968 1.9e-13
AFANOAJP_00969 2.4e-198 L Transposase
AFANOAJP_00970 6.4e-104 V ABC transporter (Permease
AFANOAJP_00971 4.1e-114 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFANOAJP_00972 1.6e-10
AFANOAJP_00973 1.2e-97 K Transcriptional regulator, TetR family
AFANOAJP_00974 4e-159 czcD P cation diffusion facilitator family transporter
AFANOAJP_00975 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
AFANOAJP_00976 6.7e-144 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
AFANOAJP_00977 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
AFANOAJP_00978 6e-08 S Hydrolases of the alpha beta superfamily
AFANOAJP_00979 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
AFANOAJP_00980 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
AFANOAJP_00983 1.2e-143 2.4.2.3 F Phosphorylase superfamily
AFANOAJP_00984 6e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
AFANOAJP_00985 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
AFANOAJP_00986 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
AFANOAJP_00988 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
AFANOAJP_00989 3.7e-190
AFANOAJP_00990 8.1e-90 FNV0100 F Belongs to the Nudix hydrolase family
AFANOAJP_00991 3.5e-28 3.4.13.21 I Protein conserved in bacteria
AFANOAJP_00993 4.3e-118 S TraX protein
AFANOAJP_00994 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
AFANOAJP_00995 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
AFANOAJP_00996 2.1e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AFANOAJP_00997 4.7e-185 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AFANOAJP_00998 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AFANOAJP_00999 3.2e-216 mesE M HlyD family secretion protein
AFANOAJP_01000 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AFANOAJP_01004 2.6e-46 S Enterocin A Immunity
AFANOAJP_01005 3.1e-10 blpU S hmm tigr01847
AFANOAJP_01007 3.1e-16
AFANOAJP_01008 1.2e-51
AFANOAJP_01012 7.4e-09 S Bacteriocin class II with double-glycine leader peptide
AFANOAJP_01013 6e-54
AFANOAJP_01015 4.9e-16
AFANOAJP_01016 2.3e-134 blpT
AFANOAJP_01017 2.2e-25
AFANOAJP_01018 3.5e-123 agrA KT phosphorelay signal transduction system
AFANOAJP_01019 2e-138 2.7.13.3 T protein histidine kinase activity
AFANOAJP_01022 1.8e-51 csm6 S Psort location Cytoplasmic, score
AFANOAJP_01023 1.7e-116 csm6 S Psort location Cytoplasmic, score
AFANOAJP_01024 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AFANOAJP_01025 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AFANOAJP_01026 8.1e-48 nylA 3.5.1.4 J Belongs to the amidase family
AFANOAJP_01027 7.9e-266 dtpT E transporter
AFANOAJP_01028 1.4e-62 yecS P ABC transporter (Permease
AFANOAJP_01029 2.3e-20 yecS P amino acid transport
AFANOAJP_01031 5.1e-163 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
AFANOAJP_01032 5.5e-77 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
AFANOAJP_01033 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
AFANOAJP_01034 4e-99 yfiF3 K sequence-specific DNA binding
AFANOAJP_01035 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AFANOAJP_01036 1.8e-240 agcS E (Alanine) symporter
AFANOAJP_01037 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AFANOAJP_01038 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
AFANOAJP_01039 3.5e-61 S haloacid dehalogenase-like hydrolase
AFANOAJP_01040 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AFANOAJP_01041 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
AFANOAJP_01042 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
AFANOAJP_01043 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
AFANOAJP_01044 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AFANOAJP_01045 8.4e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AFANOAJP_01046 3.3e-68 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AFANOAJP_01047 6.7e-44 yktA S Belongs to the UPF0223 family
AFANOAJP_01048 1.9e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
AFANOAJP_01049 7.9e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
AFANOAJP_01050 3.3e-158 pstS P phosphate
AFANOAJP_01051 1.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
AFANOAJP_01052 1.2e-155 pstA P phosphate transport system permease
AFANOAJP_01053 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFANOAJP_01054 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFANOAJP_01055 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
AFANOAJP_01056 0.0 pepN 3.4.11.2 E aminopeptidase
AFANOAJP_01057 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
AFANOAJP_01058 9.4e-186 lplA 6.3.1.20 H Lipoate-protein ligase
AFANOAJP_01059 4e-08
AFANOAJP_01060 4.7e-09
AFANOAJP_01061 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AFANOAJP_01062 5.8e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
AFANOAJP_01063 4.6e-25 tatA U protein secretion
AFANOAJP_01064 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AFANOAJP_01065 2.6e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
AFANOAJP_01066 1.5e-233 ycdB P peroxidase
AFANOAJP_01067 2.1e-152 ycdO P periplasmic lipoprotein involved in iron transport
AFANOAJP_01068 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AFANOAJP_01069 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AFANOAJP_01070 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AFANOAJP_01071 1.2e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AFANOAJP_01072 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AFANOAJP_01073 8.6e-187 3.5.1.28 M GBS Bsp-like repeat
AFANOAJP_01074 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
AFANOAJP_01075 6.4e-11 3.5.1.28 NU amidase activity
AFANOAJP_01076 0.0 lpdA 1.8.1.4 C Dehydrogenase
AFANOAJP_01077 6e-199 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFANOAJP_01078 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AFANOAJP_01079 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
AFANOAJP_01080 3.6e-46 hpk9 2.7.13.3 T protein histidine kinase activity
AFANOAJP_01081 3.5e-241 cas3 L CRISPR-associated helicase, Cas3
AFANOAJP_01082 0.0 S the current gene model (or a revised gene model) may contain a frame shift
AFANOAJP_01083 3.5e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AFANOAJP_01084 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AFANOAJP_01085 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFANOAJP_01086 1.2e-157 rssA S Phospholipase, patatin family
AFANOAJP_01087 3.9e-78 estA E GDSL-like protein
AFANOAJP_01088 2.6e-15 estA E Lysophospholipase L1 and related esterases
AFANOAJP_01089 3.7e-293 S unusual protein kinase
AFANOAJP_01090 4.9e-39 S granule-associated protein
AFANOAJP_01091 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFANOAJP_01092 2.7e-41 bglH 3.2.1.86 GT1 G beta-glucosidase activity
AFANOAJP_01093 3.8e-96 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFANOAJP_01094 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFANOAJP_01095 2.2e-199 S hmm pf01594
AFANOAJP_01096 9.8e-86 G Belongs to the phosphoglycerate mutase family
AFANOAJP_01097 1.3e-66 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
AFANOAJP_01098 5.4e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
AFANOAJP_01099 1.4e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
AFANOAJP_01100 1.1e-89 tnp L DDE domain
AFANOAJP_01101 5.9e-92 V VanZ like family
AFANOAJP_01102 1.3e-229 L Transposase
AFANOAJP_01103 1.7e-212 glf 5.4.99.9 M UDP-galactopyranose mutase
AFANOAJP_01104 3e-216 epsU S Polysaccharide biosynthesis protein
AFANOAJP_01105 6.2e-239 cps1C S Polysaccharide biosynthesis protein
AFANOAJP_01106 6.3e-86 2.7.8.12 GT2 M Glycosyltransferase like family 2
AFANOAJP_01107 3.6e-61 ywqD 2.7.10.1 D Capsular exopolysaccharide family
AFANOAJP_01108 9.1e-101 M group 2 family protein
AFANOAJP_01109 7.7e-100
AFANOAJP_01110 1.2e-71 cps1D M Domain of unknown function (DUF4422)
AFANOAJP_01111 5.6e-62 L Transposase DDE domain
AFANOAJP_01112 2.7e-73 L Transposase DDE domain
AFANOAJP_01113 2.7e-23 rgpAc GT4 M group 1 family protein
AFANOAJP_01114 2.7e-255 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
AFANOAJP_01115 2.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
AFANOAJP_01116 3.6e-107 cps4C M biosynthesis protein
AFANOAJP_01117 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
AFANOAJP_01118 2.2e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
AFANOAJP_01119 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
AFANOAJP_01120 1.5e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
AFANOAJP_01121 2.5e-43 yfeJ 6.3.5.2 F glutamine amidotransferase
AFANOAJP_01122 5.2e-110 clcA_2 P chloride
AFANOAJP_01123 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AFANOAJP_01124 8.1e-41 S Protein of unknown function (DUF1697)
AFANOAJP_01125 7.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
AFANOAJP_01126 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AFANOAJP_01128 6.1e-22 V Glucan-binding protein C
AFANOAJP_01129 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
AFANOAJP_01130 7.6e-274 pepV 3.5.1.18 E Dipeptidase
AFANOAJP_01131 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
AFANOAJP_01132 6.9e-86 XK27_03610 K Gnat family
AFANOAJP_01133 3e-33 L COG1943 Transposase and inactivated derivatives
AFANOAJP_01134 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AFANOAJP_01135 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AFANOAJP_01136 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AFANOAJP_01137 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AFANOAJP_01138 3.9e-15 M LysM domain
AFANOAJP_01139 2.9e-90 ebsA S Family of unknown function (DUF5322)
AFANOAJP_01140 4.4e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AFANOAJP_01141 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AFANOAJP_01142 4.9e-224 G COG0457 FOG TPR repeat
AFANOAJP_01143 1.1e-175 yubA S permease
AFANOAJP_01144 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
AFANOAJP_01145 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
AFANOAJP_01146 2.5e-124 ftsE D cell division ATP-binding protein FtsE
AFANOAJP_01147 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AFANOAJP_01148 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AFANOAJP_01149 1.1e-180 yjjH S Calcineurin-like phosphoesterase
AFANOAJP_01150 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AFANOAJP_01151 0.0 pacL 3.6.3.8 P cation transport ATPase
AFANOAJP_01152 2.6e-67 ywiB S Domain of unknown function (DUF1934)
AFANOAJP_01153 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
AFANOAJP_01154 9.2e-147 yidA S hydrolases of the HAD superfamily
AFANOAJP_01155 5.5e-228 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
AFANOAJP_01156 3.3e-250 L Transposase
AFANOAJP_01157 5e-35 F Protein of unknown function (DUF454)
AFANOAJP_01158 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
AFANOAJP_01159 1.9e-234 vicK 2.7.13.3 T Histidine kinase
AFANOAJP_01160 1.7e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFANOAJP_01161 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
AFANOAJP_01162 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
AFANOAJP_01163 8e-115 gltJ P ABC transporter (Permease
AFANOAJP_01164 2.2e-111 tcyB_2 P ABC transporter (permease)
AFANOAJP_01165 5.5e-129 endA F DNA RNA non-specific endonuclease
AFANOAJP_01166 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
AFANOAJP_01167 6.5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFANOAJP_01168 2.6e-09 S Protein of unknown function (DUF1146)
AFANOAJP_01169 3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AFANOAJP_01170 7.1e-15 G Domain of unknown function (DUF4832)
AFANOAJP_01171 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AFANOAJP_01172 1.6e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AFANOAJP_01173 3.5e-294 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFANOAJP_01174 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
AFANOAJP_01175 1.1e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AFANOAJP_01176 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
AFANOAJP_01177 5.8e-80
AFANOAJP_01179 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AFANOAJP_01180 2.1e-219 XK27_05110 P chloride
AFANOAJP_01181 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
AFANOAJP_01182 6.2e-70 clcA P Chloride transporter, ClC family
AFANOAJP_01183 1.9e-93 clcA P Chloride transporter, ClC family
AFANOAJP_01184 2.3e-75 fld C Flavodoxin
AFANOAJP_01185 2.5e-14 XK27_08880
AFANOAJP_01186 1.8e-125 XK27_08875 O Zinc-dependent metalloprotease
AFANOAJP_01187 3.5e-151 estA CE1 S Putative esterase
AFANOAJP_01188 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFANOAJP_01189 1.2e-135 XK27_08845 S abc transporter atp-binding protein
AFANOAJP_01190 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
AFANOAJP_01191 1.2e-177 XK27_08835 S ABC transporter substrate binding protein
AFANOAJP_01192 1.6e-16 S Domain of unknown function (DUF4649)
AFANOAJP_01194 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
AFANOAJP_01195 2.7e-26 Q the current gene model (or a revised gene model) may contain a frame shift
AFANOAJP_01196 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
AFANOAJP_01198 1.6e-249 L Transposase
AFANOAJP_01199 1.1e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AFANOAJP_01200 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AFANOAJP_01201 0.0 dnaE 2.7.7.7 L DNA polymerase
AFANOAJP_01202 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
AFANOAJP_01203 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AFANOAJP_01204 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AFANOAJP_01205 2.5e-43 ysdA L Membrane
AFANOAJP_01206 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
AFANOAJP_01207 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AFANOAJP_01208 1.3e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AFANOAJP_01209 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
AFANOAJP_01211 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AFANOAJP_01212 2.1e-84 ypmS S Protein conserved in bacteria
AFANOAJP_01213 1.3e-143 ypmR E lipolytic protein G-D-S-L family
AFANOAJP_01214 1e-148 DegV S DegV family
AFANOAJP_01215 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
AFANOAJP_01216 3.7e-73 argR K Regulates arginine biosynthesis genes
AFANOAJP_01217 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AFANOAJP_01218 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AFANOAJP_01219 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
AFANOAJP_01220 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFANOAJP_01223 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AFANOAJP_01224 2.9e-125 dnaD
AFANOAJP_01225 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AFANOAJP_01226 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AFANOAJP_01227 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
AFANOAJP_01228 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AFANOAJP_01229 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AFANOAJP_01230 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
AFANOAJP_01231 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AFANOAJP_01232 5.4e-197 L transposase, IS4 family
AFANOAJP_01233 5.6e-240 rodA D Belongs to the SEDS family
AFANOAJP_01234 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
AFANOAJP_01235 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AFANOAJP_01236 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AFANOAJP_01237 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AFANOAJP_01238 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AFANOAJP_01239 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
AFANOAJP_01240 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AFANOAJP_01241 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AFANOAJP_01242 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AFANOAJP_01243 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AFANOAJP_01245 6.6e-31 L Integrase core domain protein
AFANOAJP_01246 4.5e-55 L transposition
AFANOAJP_01247 8.2e-22 L Transposase
AFANOAJP_01248 5.2e-36 L transposase activity
AFANOAJP_01249 1.3e-22 XK27_08085
AFANOAJP_01250 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
AFANOAJP_01251 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
AFANOAJP_01252 2.6e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
AFANOAJP_01253 1.1e-121 ylfI S tigr01906
AFANOAJP_01254 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AFANOAJP_01255 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
AFANOAJP_01256 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
AFANOAJP_01259 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AFANOAJP_01260 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AFANOAJP_01261 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AFANOAJP_01262 1.1e-206 yurR 1.4.5.1 E oxidoreductase
AFANOAJP_01263 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
AFANOAJP_01264 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AFANOAJP_01265 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
AFANOAJP_01266 1.7e-70 gtrA S GtrA-like protein
AFANOAJP_01267 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFANOAJP_01268 6e-169 ybbR S Protein conserved in bacteria
AFANOAJP_01269 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AFANOAJP_01270 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
AFANOAJP_01271 8.7e-150 cobQ S glutamine amidotransferase
AFANOAJP_01272 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AFANOAJP_01273 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
AFANOAJP_01274 0.0 uup S abc transporter atp-binding protein
AFANOAJP_01275 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
AFANOAJP_01276 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
AFANOAJP_01277 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AFANOAJP_01278 1.1e-262 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
AFANOAJP_01279 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AFANOAJP_01280 7.9e-39 ptsH G phosphocarrier protein Hpr
AFANOAJP_01281 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
AFANOAJP_01282 1.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
AFANOAJP_01283 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AFANOAJP_01284 2.2e-34 nrdH O Glutaredoxin
AFANOAJP_01285 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFANOAJP_01286 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFANOAJP_01288 4.2e-71 L Transposase (IS116 IS110 IS902 family)
AFANOAJP_01289 3.3e-26 L Transposase (IS116 IS110 IS902 family)
AFANOAJP_01290 6.9e-165 ypuA S secreted protein
AFANOAJP_01291 5.4e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
AFANOAJP_01292 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFANOAJP_01293 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AFANOAJP_01294 3.4e-258 noxE P NADH oxidase
AFANOAJP_01295 1.9e-294 yfmM S abc transporter atp-binding protein
AFANOAJP_01296 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
AFANOAJP_01297 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
AFANOAJP_01298 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
AFANOAJP_01299 2e-86 S ECF-type riboflavin transporter, S component
AFANOAJP_01301 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFANOAJP_01302 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
AFANOAJP_01304 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFANOAJP_01305 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFANOAJP_01306 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AFANOAJP_01307 0.0 smc D Required for chromosome condensation and partitioning
AFANOAJP_01308 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AFANOAJP_01309 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFANOAJP_01310 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AFANOAJP_01311 7.3e-82 alkD L Dna alkylation repair
AFANOAJP_01312 2.8e-93 pat 2.3.1.183 M acetyltransferase
AFANOAJP_01313 3e-13
AFANOAJP_01314 6.8e-30
AFANOAJP_01315 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFANOAJP_01316 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AFANOAJP_01317 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
AFANOAJP_01318 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
AFANOAJP_01319 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
AFANOAJP_01320 7.4e-26
AFANOAJP_01321 9.3e-144 S ABC-2 family transporter protein
AFANOAJP_01322 3.6e-97 S transport system, permease component
AFANOAJP_01323 2.9e-79 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFANOAJP_01324 9.4e-14 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFANOAJP_01325 2.6e-192 desK 2.7.13.3 T Histidine kinase
AFANOAJP_01326 1.4e-133 yvfS V ABC-2 type transporter
AFANOAJP_01327 9.7e-158 XK27_09825 V abc transporter atp-binding protein
AFANOAJP_01331 2.3e-213 EGP Major facilitator Superfamily
AFANOAJP_01332 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
AFANOAJP_01333 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
AFANOAJP_01334 3.9e-41 3.6.1.55 F NUDIX domain
AFANOAJP_01336 3.7e-122 S An automated process has identified a potential problem with this gene model
AFANOAJP_01337 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
AFANOAJP_01338 1.4e-15 liaI KT membrane
AFANOAJP_01339 2.6e-30 liaI KT membrane
AFANOAJP_01340 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
AFANOAJP_01341 0.0 V ABC transporter (permease)
AFANOAJP_01342 5.8e-135 macB2 V ABC transporter, ATP-binding protein
AFANOAJP_01343 6.2e-166 T Histidine kinase
AFANOAJP_01344 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFANOAJP_01345 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AFANOAJP_01347 3.3e-69 pbuX F xanthine permease
AFANOAJP_01348 9.2e-119 pbuX F xanthine permease
AFANOAJP_01349 5.3e-248 norM V Multidrug efflux pump
AFANOAJP_01350 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AFANOAJP_01351 4.3e-234 brnQ E Component of the transport system for branched-chain amino acids
AFANOAJP_01352 1.9e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
AFANOAJP_01353 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
AFANOAJP_01354 9.6e-26 csbD K CsbD-like
AFANOAJP_01355 6.2e-228 yfnA E amino acid
AFANOAJP_01356 2.2e-108 XK27_02070 S nitroreductase
AFANOAJP_01357 2.1e-154 1.13.11.2 S glyoxalase
AFANOAJP_01358 3.3e-77 ywnA K Transcriptional regulator
AFANOAJP_01359 6.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
AFANOAJP_01360 5.4e-234 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFANOAJP_01361 1.3e-111 drgA C Nitroreductase
AFANOAJP_01362 1.7e-60 yoaK S Protein of unknown function (DUF1275)
AFANOAJP_01364 3.1e-161 yvgN C reductase
AFANOAJP_01365 5.6e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AFANOAJP_01366 2.4e-09
AFANOAJP_01367 1.6e-140 S Abortive infection C-terminus
AFANOAJP_01368 0.0 L DEAD-like helicases superfamily
AFANOAJP_01369 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
AFANOAJP_01370 7.1e-278 XK27_07020 S Belongs to the UPF0371 family
AFANOAJP_01372 1.1e-37 BP1961 P nitric oxide dioxygenase activity
AFANOAJP_01373 2e-53 K response regulator
AFANOAJP_01374 9.3e-72 S Signal peptide protein, YSIRK family
AFANOAJP_01375 4.5e-61
AFANOAJP_01376 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFANOAJP_01377 2.7e-89
AFANOAJP_01378 4e-20
AFANOAJP_01379 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
AFANOAJP_01380 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
AFANOAJP_01381 5.8e-109 MA20_06410 E LysE type translocator
AFANOAJP_01382 5.6e-08
AFANOAJP_01383 2.7e-09
AFANOAJP_01384 0.0 M family 8
AFANOAJP_01385 7.2e-86 L transposition
AFANOAJP_01386 3.1e-169 EGP Major Facilitator Superfamily
AFANOAJP_01387 1.5e-250 I radical SAM domain protein
AFANOAJP_01389 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AFANOAJP_01390 1.4e-150 L Integrase core domain protein
AFANOAJP_01391 1.8e-87 L transposase activity
AFANOAJP_01393 3.9e-92
AFANOAJP_01394 0.0 sbcC L ATPase involved in DNA repair
AFANOAJP_01395 3.8e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AFANOAJP_01396 0.0 lacL 3.2.1.23 G -beta-galactosidase
AFANOAJP_01397 0.0 lacS G transporter
AFANOAJP_01398 9.3e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AFANOAJP_01399 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AFANOAJP_01400 3e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
AFANOAJP_01401 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AFANOAJP_01402 2.3e-184 galR K Transcriptional regulator
AFANOAJP_01403 2.7e-08 L Integrase core domain protein
AFANOAJP_01404 1.2e-25 L transposition
AFANOAJP_01405 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
AFANOAJP_01406 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
AFANOAJP_01407 2.5e-101 V abc transporter atp-binding protein
AFANOAJP_01408 4.3e-40 V abc transporter atp-binding protein
AFANOAJP_01409 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
AFANOAJP_01410 2.3e-87 L Transposase
AFANOAJP_01411 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
AFANOAJP_01412 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
AFANOAJP_01413 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AFANOAJP_01414 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AFANOAJP_01417 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFANOAJP_01418 5.8e-175 vraS 2.7.13.3 T Histidine kinase
AFANOAJP_01419 3.7e-120 yvqF KT membrane
AFANOAJP_01420 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
AFANOAJP_01421 2e-132 stp 3.1.3.16 T phosphatase
AFANOAJP_01422 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AFANOAJP_01423 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AFANOAJP_01424 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFANOAJP_01425 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
AFANOAJP_01426 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AFANOAJP_01427 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AFANOAJP_01428 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
AFANOAJP_01429 2.1e-148 supH S overlaps another CDS with the same product name
AFANOAJP_01430 8.6e-63 yvoA_1 K Transcriptional
AFANOAJP_01431 9.8e-121 skfE V abc transporter atp-binding protein
AFANOAJP_01432 3.3e-133 V ATPase activity
AFANOAJP_01433 4.3e-172 oppF P Belongs to the ABC transporter superfamily
AFANOAJP_01434 2.2e-204 oppD P Belongs to the ABC transporter superfamily
AFANOAJP_01435 4.9e-168 amiD P ABC transporter (Permease
AFANOAJP_01436 4.2e-278 amiC P ABC transporter (Permease
AFANOAJP_01437 0.0 amiA E ABC transporter, substrate-binding protein, family 5
AFANOAJP_01438 9.1e-220 L Transposase
AFANOAJP_01439 0.0 amiA E ABC transporter, substrate-binding protein, family 5
AFANOAJP_01440 8.1e-45 L Transposase
AFANOAJP_01441 4.1e-158 L COG2801 Transposase and inactivated derivatives
AFANOAJP_01442 1e-23 oppF P Belongs to the ABC transporter superfamily
AFANOAJP_01443 3.5e-24 oppF P Belongs to the ABC transporter superfamily
AFANOAJP_01444 8.9e-40 tatD L Hydrolase, tatd
AFANOAJP_01445 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
AFANOAJP_01446 2.1e-85 L Integrase core domain protein
AFANOAJP_01447 1.1e-23 L transposase activity
AFANOAJP_01448 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
AFANOAJP_01449 2.8e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
AFANOAJP_01450 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFANOAJP_01451 7.2e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
AFANOAJP_01452 1.5e-103 yjbK S Adenylate cyclase
AFANOAJP_01453 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFANOAJP_01454 2.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
AFANOAJP_01455 3.1e-59 XK27_04120 S Putative amino acid metabolism
AFANOAJP_01456 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AFANOAJP_01457 3.6e-131 puuD T peptidase C26
AFANOAJP_01458 6.2e-120 radC E Belongs to the UPF0758 family
AFANOAJP_01459 3.4e-273 rgpF M Rhamnan synthesis protein F
AFANOAJP_01460 9e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AFANOAJP_01461 5.4e-139 rgpC GM Transport permease protein
AFANOAJP_01462 4.8e-171 rgpB GT2 M Glycosyltransferase, group 2 family protein
AFANOAJP_01463 9.5e-222 rgpA GT4 M Domain of unknown function (DUF1972)
AFANOAJP_01464 5e-174 S Glucosyl transferase GtrII
AFANOAJP_01465 1.8e-28 S Glucosyl transferase GtrII
AFANOAJP_01466 1.6e-219 GT4 M transferase activity, transferring glycosyl groups
AFANOAJP_01467 2e-217 M Psort location CytoplasmicMembrane, score
AFANOAJP_01468 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
AFANOAJP_01469 9.1e-152 2.4.1.60 S Glycosyltransferase group 2 family protein
AFANOAJP_01470 4.6e-42 S Uncharacterized conserved protein (DUF2304)
AFANOAJP_01471 4.5e-129 arnC M group 2 family protein
AFANOAJP_01472 1.1e-181 cpsIaJ S Glycosyltransferase like family 2
AFANOAJP_01473 9.3e-186 S Glycosyltransferase like family 2
AFANOAJP_01474 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
AFANOAJP_01475 6.9e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AFANOAJP_01476 5.3e-237 S Predicted membrane protein (DUF2142)
AFANOAJP_01477 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
AFANOAJP_01478 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
AFANOAJP_01479 3.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AFANOAJP_01480 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AFANOAJP_01481 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AFANOAJP_01482 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
AFANOAJP_01483 2.1e-202 arcT 2.6.1.1 E Aminotransferase
AFANOAJP_01484 2.5e-136 ET ABC transporter
AFANOAJP_01485 2.2e-140 ET Belongs to the bacterial solute-binding protein 3 family
AFANOAJP_01486 2.9e-84 mutT 3.6.1.55 F Nudix family
AFANOAJP_01487 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AFANOAJP_01489 1.2e-55 V CAAX protease self-immunity
AFANOAJP_01490 7.6e-32 S CAAX amino terminal protease family protein
AFANOAJP_01491 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
AFANOAJP_01492 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
AFANOAJP_01493 2.4e-16 XK27_00735
AFANOAJP_01494 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFANOAJP_01496 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFANOAJP_01499 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
AFANOAJP_01500 6.6e-30 ycaO O OsmC-like protein
AFANOAJP_01502 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
AFANOAJP_01504 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
AFANOAJP_01505 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AFANOAJP_01506 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AFANOAJP_01507 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AFANOAJP_01508 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
AFANOAJP_01509 1.6e-297 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AFANOAJP_01510 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFANOAJP_01511 2.6e-109 3.1.3.18 S IA, variant 1
AFANOAJP_01512 2.2e-117 lrgB M effector of murein hydrolase
AFANOAJP_01513 7.7e-56 lrgA S Effector of murein hydrolase LrgA
AFANOAJP_01515 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
AFANOAJP_01516 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
AFANOAJP_01517 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFANOAJP_01518 3.9e-104 wecD M Acetyltransferase GNAT family
AFANOAJP_01519 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AFANOAJP_01520 9.8e-71 GK ROK family
AFANOAJP_01521 2.4e-30 GK ROK family
AFANOAJP_01522 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
AFANOAJP_01523 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
AFANOAJP_01524 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
AFANOAJP_01525 2.3e-206 potD P spermidine putrescine ABC transporter
AFANOAJP_01526 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
AFANOAJP_01527 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
AFANOAJP_01528 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AFANOAJP_01529 7.8e-171 murB 1.3.1.98 M cell wall formation
AFANOAJP_01530 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AFANOAJP_01531 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AFANOAJP_01532 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
AFANOAJP_01533 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AFANOAJP_01534 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
AFANOAJP_01535 0.0 ydaO E amino acid
AFANOAJP_01536 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AFANOAJP_01537 4.1e-37 ylqC L Belongs to the UPF0109 family
AFANOAJP_01538 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AFANOAJP_01539 2.6e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
AFANOAJP_01540 2e-157 xth 3.1.11.2 L exodeoxyribonuclease III
AFANOAJP_01541 2.1e-74 S QueT transporter
AFANOAJP_01542 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
AFANOAJP_01543 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
AFANOAJP_01544 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AFANOAJP_01545 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AFANOAJP_01546 3.7e-85 ccl S cog cog4708
AFANOAJP_01547 7.4e-164 rbn E Belongs to the UPF0761 family
AFANOAJP_01548 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
AFANOAJP_01549 3.3e-231 ytoI K transcriptional regulator containing CBS domains
AFANOAJP_01550 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
AFANOAJP_01551 4.5e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFANOAJP_01552 0.0 comEC S Competence protein ComEC
AFANOAJP_01553 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
AFANOAJP_01554 3.7e-142 plsC 2.3.1.51 I Acyltransferase
AFANOAJP_01555 1.8e-140 nodB3 G deacetylase
AFANOAJP_01556 7.1e-141 yabB 2.1.1.223 L Methyltransferase
AFANOAJP_01557 1e-41 yazA L endonuclease containing a URI domain
AFANOAJP_01558 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AFANOAJP_01559 2.3e-154 corA P CorA-like protein
AFANOAJP_01560 5.6e-62 yjqA S Bacterial PH domain
AFANOAJP_01561 7.8e-100 thiT S Thiamine transporter
AFANOAJP_01562 2.3e-66 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AFANOAJP_01563 1.4e-59 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AFANOAJP_01564 1.9e-201 yjbB G Permeases of the major facilitator superfamily
AFANOAJP_01565 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AFANOAJP_01566 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
AFANOAJP_01567 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AFANOAJP_01571 1.1e-155 cjaA ET ABC transporter substrate-binding protein
AFANOAJP_01572 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
AFANOAJP_01573 1.3e-114 P ABC transporter (Permease
AFANOAJP_01574 1e-114 papP P ABC transporter (Permease
AFANOAJP_01575 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AFANOAJP_01576 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
AFANOAJP_01577 0.0 copA 3.6.3.54 P P-type ATPase
AFANOAJP_01578 2.7e-73 copY K Copper transport repressor, CopY TcrY family
AFANOAJP_01579 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AFANOAJP_01580 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AFANOAJP_01581 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
AFANOAJP_01582 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
AFANOAJP_01583 8.7e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AFANOAJP_01584 1.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
AFANOAJP_01585 8.7e-259 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AFANOAJP_01586 1.3e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
AFANOAJP_01587 1.8e-245 L Transposase
AFANOAJP_01588 1.7e-51
AFANOAJP_01589 0.0 ctpE P E1-E2 ATPase
AFANOAJP_01590 3.9e-26
AFANOAJP_01591 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AFANOAJP_01592 5.1e-47 L transposase activity
AFANOAJP_01593 1.4e-81 K transcriptional regulator, MerR family
AFANOAJP_01594 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
AFANOAJP_01595 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
AFANOAJP_01596 1.6e-63 XK27_02560 S cog cog2151
AFANOAJP_01597 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AFANOAJP_01598 7.7e-227 ytfP S Flavoprotein
AFANOAJP_01600 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AFANOAJP_01601 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
AFANOAJP_01602 2.7e-183 ecsB U ABC transporter
AFANOAJP_01603 2.3e-133 ecsA V abc transporter atp-binding protein
AFANOAJP_01604 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
AFANOAJP_01605 6e-11
AFANOAJP_01606 1.3e-56 S CD20-like family
AFANOAJP_01607 3.2e-110
AFANOAJP_01608 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
AFANOAJP_01609 6.9e-206 ylbM S Belongs to the UPF0348 family
AFANOAJP_01610 2e-140 yqeM Q Methyltransferase domain protein
AFANOAJP_01611 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AFANOAJP_01612 4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
AFANOAJP_01613 2.7e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AFANOAJP_01614 3.5e-49 yhbY J RNA-binding protein
AFANOAJP_01615 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
AFANOAJP_01616 1.8e-98 yqeG S hydrolase of the HAD superfamily
AFANOAJP_01617 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AFANOAJP_01618 5.8e-24
AFANOAJP_01619 3.5e-13
AFANOAJP_01620 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFANOAJP_01621 1.8e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AFANOAJP_01622 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFANOAJP_01623 9.8e-25 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
AFANOAJP_01624 1.8e-30 M lipopolysaccharide 3-alpha-galactosyltransferase activity
AFANOAJP_01625 1.8e-253 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFANOAJP_01626 6.7e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AFANOAJP_01627 1.6e-154 hlpA M Belongs to the NlpA lipoprotein family
AFANOAJP_01628 6.8e-101 pncA Q isochorismatase
AFANOAJP_01629 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AFANOAJP_01630 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
AFANOAJP_01631 2.4e-75 XK27_03180 T universal stress protein
AFANOAJP_01633 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AFANOAJP_01634 9.9e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
AFANOAJP_01635 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
AFANOAJP_01636 3.3e-250 L Transposase
AFANOAJP_01637 0.0 yjcE P NhaP-type Na H and K H antiporters
AFANOAJP_01639 2e-97 ytqB 2.1.1.176 J (SAM)-dependent
AFANOAJP_01640 5.7e-180 yhcC S radical SAM protein
AFANOAJP_01641 7.8e-194 ylbL T Belongs to the peptidase S16 family
AFANOAJP_01642 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AFANOAJP_01643 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
AFANOAJP_01644 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AFANOAJP_01645 1.9e-09 S Protein of unknown function (DUF4059)
AFANOAJP_01646 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
AFANOAJP_01647 1e-162 yxeN P ABC transporter (Permease
AFANOAJP_01648 1.2e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
AFANOAJP_01650 1e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFANOAJP_01651 0.0 pflB 2.3.1.54 C formate acetyltransferase'
AFANOAJP_01652 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
AFANOAJP_01653 1.5e-83 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFANOAJP_01654 1.7e-30 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
AFANOAJP_01655 6.5e-31 D nuclear chromosome segregation
AFANOAJP_01656 4.1e-33 L DNA integration
AFANOAJP_01657 3.2e-124 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
AFANOAJP_01658 1.5e-127 ybbM S transport system, permease component
AFANOAJP_01659 1.2e-117 ybbL S abc transporter atp-binding protein
AFANOAJP_01660 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
AFANOAJP_01661 4.6e-140 cppA E CppA N-terminal
AFANOAJP_01662 5e-44 V CAAX protease self-immunity
AFANOAJP_01663 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
AFANOAJP_01664 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AFANOAJP_01666 0.0 mdlB V abc transporter atp-binding protein
AFANOAJP_01667 0.0 mdlA V abc transporter atp-binding protein
AFANOAJP_01669 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
AFANOAJP_01670 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AFANOAJP_01671 2.3e-72 yutD J protein conserved in bacteria
AFANOAJP_01672 1.9e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
AFANOAJP_01674 6.1e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AFANOAJP_01675 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AFANOAJP_01676 0.0 ftsI 3.4.16.4 M penicillin-binding protein
AFANOAJP_01677 4.3e-47 ftsL D cell division protein FtsL
AFANOAJP_01678 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AFANOAJP_01679 1.6e-65
AFANOAJP_01680 7.4e-27
AFANOAJP_01681 2.6e-30
AFANOAJP_01683 9.7e-32 yhaI J Protein of unknown function (DUF805)
AFANOAJP_01684 1.1e-12 D nuclear chromosome segregation
AFANOAJP_01685 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AFANOAJP_01686 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AFANOAJP_01687 3.1e-287 XK27_00765
AFANOAJP_01688 1.4e-133 ecsA_2 V abc transporter atp-binding protein
AFANOAJP_01689 2.5e-47 S Protein of unknown function (DUF554)
AFANOAJP_01690 8.5e-32 S Protein of unknown function (DUF554)
AFANOAJP_01691 1.6e-11 S Protein of unknown function (DUF554)
AFANOAJP_01692 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AFANOAJP_01693 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AFANOAJP_01694 2.6e-121 liaI S membrane
AFANOAJP_01695 5.2e-75 XK27_02470 K LytTr DNA-binding domain
AFANOAJP_01696 3.6e-66 KT response to antibiotic
AFANOAJP_01697 2.6e-80 yebC M Membrane
AFANOAJP_01698 2.9e-18 yebC M Membrane
AFANOAJP_01699 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
AFANOAJP_01700 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
AFANOAJP_01701 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AFANOAJP_01702 2e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFANOAJP_01703 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AFANOAJP_01704 1.4e-179 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AFANOAJP_01705 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AFANOAJP_01707 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
AFANOAJP_01708 7.7e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
AFANOAJP_01709 0.0 scrA 2.7.1.211 G pts system
AFANOAJP_01710 5.4e-291 scrB 3.2.1.26 GH32 G invertase
AFANOAJP_01711 3.7e-168 scrR K Transcriptional
AFANOAJP_01712 3.3e-250 L Transposase
AFANOAJP_01713 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AFANOAJP_01714 3.4e-62 yqhY S protein conserved in bacteria
AFANOAJP_01715 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AFANOAJP_01716 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
AFANOAJP_01717 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
AFANOAJP_01719 2e-09 V 'abc transporter, ATP-binding protein
AFANOAJP_01720 4.1e-21 V 'abc transporter, ATP-binding protein
AFANOAJP_01723 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AFANOAJP_01724 2e-169 corA P COG0598 Mg2 and Co2 transporters
AFANOAJP_01725 3.1e-124 XK27_01040 S Pfam PF06570
AFANOAJP_01727 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AFANOAJP_01728 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AFANOAJP_01729 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
AFANOAJP_01730 3.6e-41 XK27_05745
AFANOAJP_01731 2.3e-228 mutY L A G-specific adenine glycosylase
AFANOAJP_01736 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AFANOAJP_01737 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AFANOAJP_01738 1e-93 cvpA S toxin biosynthetic process
AFANOAJP_01739 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AFANOAJP_01740 1e-159 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFANOAJP_01741 3.9e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AFANOAJP_01742 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AFANOAJP_01743 1.2e-47 azlD E branched-chain amino acid
AFANOAJP_01744 6e-46 azlC E AzlC protein
AFANOAJP_01745 1.7e-46 azlC E AzlC protein
AFANOAJP_01746 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AFANOAJP_01747 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
AFANOAJP_01748 2.8e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
AFANOAJP_01749 2.5e-33 ykzG S Belongs to the UPF0356 family
AFANOAJP_01750 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFANOAJP_01751 2.7e-40 pscB M CHAP domain protein
AFANOAJP_01752 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
AFANOAJP_01753 8.5e-63 glnR K Transcriptional regulator
AFANOAJP_01754 1.3e-87 S Fusaric acid resistance protein-like
AFANOAJP_01755 3e-13
AFANOAJP_01756 3.1e-22
AFANOAJP_01757 3.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AFANOAJP_01758 1e-51 L Transposase
AFANOAJP_01759 7.4e-23 L Transposase
AFANOAJP_01760 9.4e-47 L transposition
AFANOAJP_01761 4.2e-86 L Integrase core domain protein
AFANOAJP_01762 4.3e-186 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AFANOAJP_01763 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AFANOAJP_01764 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AFANOAJP_01765 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AFANOAJP_01766 1.1e-142 purR 2.4.2.7 F operon repressor
AFANOAJP_01767 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
AFANOAJP_01768 6.9e-173 rmuC S RmuC domain protein
AFANOAJP_01769 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
AFANOAJP_01770 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AFANOAJP_01771 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AFANOAJP_01773 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AFANOAJP_01774 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AFANOAJP_01775 4.5e-143 tatD L Hydrolase, tatd
AFANOAJP_01776 5.5e-74 yccU S CoA-binding protein
AFANOAJP_01777 4.8e-51 trxA O Belongs to the thioredoxin family
AFANOAJP_01778 7.8e-143 S Macro domain protein
AFANOAJP_01779 3.1e-10 L thioesterase
AFANOAJP_01780 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
AFANOAJP_01784 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AFANOAJP_01785 1e-33 L Transposase
AFANOAJP_01786 1e-13 rpmH J Ribosomal protein L34
AFANOAJP_01787 1e-185 jag S RNA-binding protein
AFANOAJP_01788 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFANOAJP_01789 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AFANOAJP_01790 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
AFANOAJP_01791 9.9e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AFANOAJP_01792 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AFANOAJP_01793 9.5e-63 amiA E transmembrane transport
AFANOAJP_01794 2e-41 amiA E transmembrane transport
AFANOAJP_01795 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
AFANOAJP_01796 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
AFANOAJP_01797 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AFANOAJP_01798 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AFANOAJP_01799 9.2e-51 S Protein of unknown function (DUF3397)
AFANOAJP_01800 6.6e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
AFANOAJP_01801 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
AFANOAJP_01802 1.5e-10 WQ51_05710 S Mitochondrial biogenesis AIM24
AFANOAJP_01803 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AFANOAJP_01804 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
AFANOAJP_01805 2.4e-19 XK27_09620 S FMN reductase (NADPH) activity
AFANOAJP_01806 3.1e-75 XK27_09620 S reductase
AFANOAJP_01807 5.8e-61 XK27_09615 C reductase
AFANOAJP_01808 3.3e-135 XK27_09615 C reductase
AFANOAJP_01809 8.1e-91 fnt P Formate nitrite transporter
AFANOAJP_01810 6.5e-83 XK27_08585 S Psort location CytoplasmicMembrane, score
AFANOAJP_01811 7.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AFANOAJP_01812 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AFANOAJP_01813 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
AFANOAJP_01814 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AFANOAJP_01815 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AFANOAJP_01816 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AFANOAJP_01817 6e-48 S glycolate biosynthetic process
AFANOAJP_01818 1.5e-64 S phosphatase activity
AFANOAJP_01819 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
AFANOAJP_01822 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AFANOAJP_01823 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AFANOAJP_01824 8.3e-37 yeeD O sulfur carrier activity
AFANOAJP_01825 7.8e-191 yeeE S Sulphur transport
AFANOAJP_01826 1.8e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFANOAJP_01827 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AFANOAJP_01828 1.2e-08 S Domain of unknown function (DUF4651)
AFANOAJP_01829 5.7e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
AFANOAJP_01830 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFANOAJP_01831 3.9e-111 S CAAX amino terminal protease family protein
AFANOAJP_01833 5e-67 V CAAX protease self-immunity
AFANOAJP_01834 1.4e-33 V CAAX protease self-immunity
AFANOAJP_01835 8.8e-27 lanR K sequence-specific DNA binding
AFANOAJP_01836 6.5e-204 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFANOAJP_01837 2.2e-176 ytxK 2.1.1.72 L DNA methylase
AFANOAJP_01838 5.8e-12 comGF U Putative Competence protein ComGF
AFANOAJP_01839 1.3e-70 comGF U Competence protein ComGF
AFANOAJP_01840 3.2e-15 NU Type II secretory pathway pseudopilin
AFANOAJP_01841 3e-57 cglD NU Competence protein
AFANOAJP_01842 8.5e-43 comGC U Required for transformation and DNA binding
AFANOAJP_01843 3e-145 cglB NU type II secretion system
AFANOAJP_01844 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AFANOAJP_01845 1e-68 S cog cog4699
AFANOAJP_01846 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFANOAJP_01847 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFANOAJP_01848 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFANOAJP_01849 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AFANOAJP_01850 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AFANOAJP_01851 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
AFANOAJP_01852 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
AFANOAJP_01853 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AFANOAJP_01854 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AFANOAJP_01855 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
AFANOAJP_01856 1.8e-57 asp S cog cog1302
AFANOAJP_01857 3.2e-226 norN V Mate efflux family protein
AFANOAJP_01858 1.9e-278 thrC 4.2.3.1 E Threonine synthase
AFANOAJP_01859 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AFANOAJP_01860 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
AFANOAJP_01861 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AFANOAJP_01862 1.7e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AFANOAJP_01863 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
AFANOAJP_01864 0.0 pepO 3.4.24.71 O Peptidase family M13
AFANOAJP_01865 1.8e-37 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AFANOAJP_01866 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AFANOAJP_01867 5e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AFANOAJP_01868 1.4e-54 treB 2.7.1.201 G PTS System
AFANOAJP_01869 5.8e-21 treR K DNA-binding transcription factor activity
AFANOAJP_01870 8.6e-87 treR K trehalose operon
AFANOAJP_01871 7.4e-95 ywlG S Belongs to the UPF0340 family
AFANOAJP_01874 2.7e-13 L PFAM Integrase, catalytic core
AFANOAJP_01875 2.3e-114 L PFAM Integrase, catalytic core
AFANOAJP_01876 3.3e-46 K Putative DNA-binding domain
AFANOAJP_01877 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
AFANOAJP_01878 5.1e-125 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFANOAJP_01879 3.5e-134 HJ the current gene model (or a revised gene model) may contain a frame shift
AFANOAJP_01880 3.3e-250 L Transposase
AFANOAJP_01883 1.5e-30
AFANOAJP_01884 4e-26
AFANOAJP_01885 1.2e-39 isp2 S pathogenesis
AFANOAJP_01886 4.4e-15
AFANOAJP_01888 8.8e-131 L DNA integration
AFANOAJP_01889 5.3e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
AFANOAJP_01891 1.1e-109 6.3.2.2 H ergothioneine biosynthetic process
AFANOAJP_01892 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
AFANOAJP_01893 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
AFANOAJP_01894 2.7e-13 L PFAM Integrase, catalytic core
AFANOAJP_01895 1.1e-95 L PFAM Integrase, catalytic core
AFANOAJP_01896 3.3e-62 rplQ J ribosomal protein l17
AFANOAJP_01897 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFANOAJP_01898 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AFANOAJP_01899 2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFANOAJP_01900 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AFANOAJP_01901 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AFANOAJP_01902 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AFANOAJP_01903 5.1e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AFANOAJP_01904 1.3e-57 rplO J binds to the 23S rRNA
AFANOAJP_01905 2.5e-23 rpmD J ribosomal protein l30
AFANOAJP_01906 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AFANOAJP_01907 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AFANOAJP_01908 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AFANOAJP_01909 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AFANOAJP_01910 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFANOAJP_01911 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFANOAJP_01912 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AFANOAJP_01913 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AFANOAJP_01914 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AFANOAJP_01915 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
AFANOAJP_01916 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AFANOAJP_01917 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AFANOAJP_01918 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AFANOAJP_01919 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AFANOAJP_01920 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFANOAJP_01921 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AFANOAJP_01922 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
AFANOAJP_01923 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AFANOAJP_01924 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
AFANOAJP_01925 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AFANOAJP_01926 0.0 XK27_09800 I Acyltransferase
AFANOAJP_01927 1.7e-35 XK27_09805 S MORN repeat protein
AFANOAJP_01928 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AFANOAJP_01929 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AFANOAJP_01930 4.6e-83 adk 2.7.4.3 F topology modulation protein
AFANOAJP_01931 3.1e-172 yxaM EGP Major facilitator Superfamily
AFANOAJP_01932 7.4e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
AFANOAJP_01933 1.1e-31 L Transposase
AFANOAJP_01934 1.7e-176 L Transposase
AFANOAJP_01936 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AFANOAJP_01937 0.0 KLT serine threonine protein kinase
AFANOAJP_01938 2.1e-280 V ABC transporter
AFANOAJP_01939 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AFANOAJP_01940 1.4e-127 Z012_04635 K sequence-specific DNA binding
AFANOAJP_01942 6.3e-16 C Radical SAM
AFANOAJP_01943 3.4e-191 C Radical SAM
AFANOAJP_01944 4.3e-286 V ABC transporter transmembrane region
AFANOAJP_01945 2.5e-89 K sequence-specific DNA binding
AFANOAJP_01946 1e-36 L Replication initiation factor
AFANOAJP_01947 1.4e-107 L Replication initiation factor
AFANOAJP_01948 1.9e-18 S Domain of unknown function (DUF3173)
AFANOAJP_01949 8.2e-151 int L Belongs to the 'phage' integrase family
AFANOAJP_01951 4.4e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
AFANOAJP_01952 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AFANOAJP_01953 2.8e-44 yrzL S Belongs to the UPF0297 family
AFANOAJP_01954 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AFANOAJP_01955 4.2e-44 yrzB S Belongs to the UPF0473 family
AFANOAJP_01956 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
AFANOAJP_01957 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AFANOAJP_01958 7.5e-14
AFANOAJP_01959 2.6e-91 XK27_10930 K acetyltransferase
AFANOAJP_01960 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AFANOAJP_01961 1.8e-147 yaaA S Belongs to the UPF0246 family
AFANOAJP_01962 2.4e-167 XK27_01785 S cog cog1284
AFANOAJP_01963 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AFANOAJP_01965 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
AFANOAJP_01966 5.7e-52 metE 2.1.1.14 E Methionine synthase
AFANOAJP_01967 7.6e-64 metE 2.1.1.14 E Methionine synthase
AFANOAJP_01968 9.2e-36 metE 2.1.1.14 E Methionine synthase
AFANOAJP_01969 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AFANOAJP_01970 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AFANOAJP_01972 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
AFANOAJP_01973 2.7e-95 S Hydrophobic domain protein
AFANOAJP_01975 3.7e-27 S Membrane
AFANOAJP_01976 3.1e-101
AFANOAJP_01977 1.8e-23 S Small integral membrane protein
AFANOAJP_01978 1.1e-71 M Protein conserved in bacteria
AFANOAJP_01979 4.9e-12 K CsbD-like
AFANOAJP_01980 3.5e-97 nudL L hydrolase
AFANOAJP_01981 3.4e-13 nudL L hydrolase
AFANOAJP_01982 4e-19 K negative regulation of transcription, DNA-templated
AFANOAJP_01983 1.7e-23 K negative regulation of transcription, DNA-templated
AFANOAJP_01985 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
AFANOAJP_01986 1.8e-88 S Putative adhesin
AFANOAJP_01987 3.9e-161 XK27_06930 V domain protein
AFANOAJP_01988 6.4e-96 XK27_06935 K transcriptional regulator
AFANOAJP_01989 2e-53 ypaA S membrane
AFANOAJP_01990 3e-08
AFANOAJP_01991 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AFANOAJP_01992 2.4e-47 veg S Biofilm formation stimulator VEG
AFANOAJP_01993 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AFANOAJP_01994 3.9e-70 rplI J binds to the 23S rRNA
AFANOAJP_01995 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AFANOAJP_01996 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AFANOAJP_01997 4.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AFANOAJP_01998 0.0 S Bacterial membrane protein, YfhO
AFANOAJP_01999 4.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
AFANOAJP_02000 1.7e-91 lytE M LysM domain protein
AFANOAJP_02001 1.3e-237 L Transposase
AFANOAJP_02002 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFANOAJP_02003 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFANOAJP_02004 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFANOAJP_02005 1.2e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFANOAJP_02006 6.3e-138 ymfM S sequence-specific DNA binding
AFANOAJP_02007 3.1e-242 ymfH S Peptidase M16
AFANOAJP_02008 1.8e-234 ymfF S Peptidase M16
AFANOAJP_02009 1.6e-45 yaaA S S4 domain protein YaaA
AFANOAJP_02010 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AFANOAJP_02011 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
AFANOAJP_02012 3.1e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
AFANOAJP_02013 5.4e-153 yvjA S membrane
AFANOAJP_02014 3.3e-305 ybiT S abc transporter atp-binding protein
AFANOAJP_02015 0.0 XK27_10405 S Bacterial membrane protein YfhO
AFANOAJP_02019 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
AFANOAJP_02020 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AFANOAJP_02021 2.5e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
AFANOAJP_02022 8.5e-134 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)