ORF_ID e_value Gene_name EC_number CAZy COGs Description
CMAJJCLH_00002 3.1e-87 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
CMAJJCLH_00003 1.5e-217 L Probable transposase
CMAJJCLH_00004 3e-125 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
CMAJJCLH_00005 9.1e-31 L Helix-turn-helix domain
CMAJJCLH_00006 1.8e-61 yvdD 3.2.2.10 S Possible lysine decarboxylase
CMAJJCLH_00007 2.8e-16 WQ51_02665 S Protein of unknown function (DUF3042)
CMAJJCLH_00008 5.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMAJJCLH_00009 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
CMAJJCLH_00010 1.3e-45 glnR K Transcriptional regulator
CMAJJCLH_00011 2e-247 glnA 6.3.1.2 E glutamine synthetase
CMAJJCLH_00013 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CMAJJCLH_00014 2.7e-48 S Domain of unknown function (DUF956)
CMAJJCLH_00015 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CMAJJCLH_00016 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CMAJJCLH_00017 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMAJJCLH_00018 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
CMAJJCLH_00019 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CMAJJCLH_00020 1.7e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CMAJJCLH_00021 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMAJJCLH_00022 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
CMAJJCLH_00023 4.8e-170 nusA K Participates in both transcription termination and antitermination
CMAJJCLH_00024 1.4e-39 ylxR K Protein of unknown function (DUF448)
CMAJJCLH_00025 6.9e-26 ylxQ J ribosomal protein
CMAJJCLH_00026 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CMAJJCLH_00027 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CMAJJCLH_00028 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CMAJJCLH_00029 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CMAJJCLH_00030 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CMAJJCLH_00031 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CMAJJCLH_00032 1.5e-274 dnaK O Heat shock 70 kDa protein
CMAJJCLH_00033 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CMAJJCLH_00034 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CMAJJCLH_00036 9.2e-206 glnP P ABC transporter
CMAJJCLH_00037 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMAJJCLH_00038 1.5e-31
CMAJJCLH_00039 2e-111 ampC V Beta-lactamase
CMAJJCLH_00040 3.5e-110 cobQ S glutamine amidotransferase
CMAJJCLH_00041 1e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
CMAJJCLH_00042 6.8e-86 tdk 2.7.1.21 F thymidine kinase
CMAJJCLH_00043 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMAJJCLH_00044 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CMAJJCLH_00045 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CMAJJCLH_00046 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CMAJJCLH_00047 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
CMAJJCLH_00048 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMAJJCLH_00049 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMAJJCLH_00050 4.1e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMAJJCLH_00051 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMAJJCLH_00052 5.1e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMAJJCLH_00053 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMAJJCLH_00054 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CMAJJCLH_00055 2.2e-55
CMAJJCLH_00056 3.1e-30 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CMAJJCLH_00057 3.1e-30 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CMAJJCLH_00058 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CMAJJCLH_00059 6.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CMAJJCLH_00060 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
CMAJJCLH_00061 1.1e-149 EGP Sugar (and other) transporter
CMAJJCLH_00063 1.8e-38
CMAJJCLH_00064 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CMAJJCLH_00065 1.5e-22 S Family of unknown function (DUF5322)
CMAJJCLH_00066 3.1e-36 rnhA 3.1.26.4 L Ribonuclease HI
CMAJJCLH_00067 6.1e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CMAJJCLH_00068 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CMAJJCLH_00070 9.2e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CMAJJCLH_00071 1.2e-171 patA 2.6.1.1 E Aminotransferase
CMAJJCLH_00072 1.1e-114 glcR K DeoR C terminal sensor domain
CMAJJCLH_00073 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
CMAJJCLH_00074 4.7e-134 K Transcriptional regulator
CMAJJCLH_00075 2e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMAJJCLH_00076 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CMAJJCLH_00077 3.8e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CMAJJCLH_00078 7.4e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CMAJJCLH_00079 3.5e-204 pyrP F Permease
CMAJJCLH_00080 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMAJJCLH_00081 1.4e-127 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMAJJCLH_00082 3.4e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMAJJCLH_00083 5.1e-57 3.1.3.18 J HAD-hyrolase-like
CMAJJCLH_00084 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CMAJJCLH_00085 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CMAJJCLH_00086 4.8e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CMAJJCLH_00087 1.9e-116 prmA J Ribosomal protein L11 methyltransferase
CMAJJCLH_00088 1.7e-42 XK27_03960 S Protein of unknown function (DUF3013)
CMAJJCLH_00089 3.9e-144 iunH2 3.2.2.1 F nucleoside hydrolase
CMAJJCLH_00090 6.4e-12
CMAJJCLH_00091 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMAJJCLH_00092 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
CMAJJCLH_00093 1.8e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CMAJJCLH_00094 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMAJJCLH_00095 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMAJJCLH_00096 6.9e-43 yodB K Transcriptional regulator, HxlR family
CMAJJCLH_00097 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
CMAJJCLH_00098 1e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMAJJCLH_00102 5.9e-132 lys 3.5.1.104 M Glycosyl hydrolases family 25
CMAJJCLH_00103 6.5e-10 hol S Bacteriophage holin
CMAJJCLH_00105 2e-32 dprA LU DNA protecting protein DprA
CMAJJCLH_00106 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMAJJCLH_00107 2.8e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CMAJJCLH_00108 3.6e-24 yozE S Belongs to the UPF0346 family
CMAJJCLH_00109 8.8e-54 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
CMAJJCLH_00110 4.5e-81 ypmR E GDSL-like Lipase/Acylhydrolase
CMAJJCLH_00112 3.5e-113 S Aldo keto reductase
CMAJJCLH_00113 1.1e-35 K helix_turn_helix, mercury resistance
CMAJJCLH_00114 8.7e-135 yvgN C Aldo keto reductase
CMAJJCLH_00115 3.2e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CMAJJCLH_00116 1.3e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CMAJJCLH_00117 4.2e-275 yfmR S ABC transporter, ATP-binding protein
CMAJJCLH_00118 3.9e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CMAJJCLH_00119 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CMAJJCLH_00120 7.9e-107 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMAJJCLH_00121 3e-68 xerD L Phage integrase, N-terminal SAM-like domain
CMAJJCLH_00123 1.4e-56 yqeY S YqeY-like protein
CMAJJCLH_00124 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CMAJJCLH_00125 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CMAJJCLH_00128 4.9e-99 epsJ1 M Glycosyltransferase like family 2
CMAJJCLH_00129 3.7e-84 M Glycosyltransferase sugar-binding region containing DXD motif
CMAJJCLH_00130 3.6e-92 M transferase activity, transferring glycosyl groups
CMAJJCLH_00131 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMAJJCLH_00132 2.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMAJJCLH_00133 1.5e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMAJJCLH_00134 5.1e-56 dnaD L DnaD domain protein
CMAJJCLH_00135 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
CMAJJCLH_00136 3.1e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CMAJJCLH_00137 3.1e-36 ypmB S Protein conserved in bacteria
CMAJJCLH_00138 3.4e-225 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CMAJJCLH_00139 9.5e-95 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
CMAJJCLH_00140 1.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CMAJJCLH_00141 6.7e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
CMAJJCLH_00142 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CMAJJCLH_00143 8.4e-105 holA 2.7.7.7 L DNA polymerase III delta subunit
CMAJJCLH_00144 4.7e-156 comEC S Competence protein ComEC
CMAJJCLH_00145 2e-69 comEB 3.5.4.12 F ComE operon protein 2
CMAJJCLH_00146 3.1e-50 comEA L Competence protein ComEA
CMAJJCLH_00147 3.4e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
CMAJJCLH_00148 4e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CMAJJCLH_00149 2.2e-20
CMAJJCLH_00151 2.3e-122 K LysR substrate binding domain
CMAJJCLH_00152 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMAJJCLH_00154 8.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
CMAJJCLH_00155 2e-17
CMAJJCLH_00156 1.9e-104 azlC E AzlC protein
CMAJJCLH_00157 1.3e-38 azlD S branched-chain amino acid
CMAJJCLH_00158 3.6e-66 I alpha/beta hydrolase fold
CMAJJCLH_00159 2.8e-26
CMAJJCLH_00160 2.8e-58 3.6.1.27 I phosphatase
CMAJJCLH_00161 1.6e-22
CMAJJCLH_00162 4.5e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CMAJJCLH_00163 6.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
CMAJJCLH_00164 3.1e-27 cspC K Cold shock protein
CMAJJCLH_00165 4.3e-82 thrE S Putative threonine/serine exporter
CMAJJCLH_00166 6.3e-49 S Threonine/Serine exporter, ThrE
CMAJJCLH_00167 1.2e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CMAJJCLH_00168 1.6e-85 S Sucrose-6F-phosphate phosphohydrolase
CMAJJCLH_00169 1.9e-34 trxA O Belongs to the thioredoxin family
CMAJJCLH_00170 9.4e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMAJJCLH_00171 2e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMAJJCLH_00172 3.3e-65 degV S Uncharacterised protein, DegV family COG1307
CMAJJCLH_00174 4.3e-54 queT S QueT transporter
CMAJJCLH_00175 7.3e-33 XK27_01315 S Protein of unknown function (DUF2829)
CMAJJCLH_00176 1.2e-100 IQ Enoyl-(Acyl carrier protein) reductase
CMAJJCLH_00177 1e-111 argE 3.5.1.18 E Peptidase dimerisation domain
CMAJJCLH_00178 1.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CMAJJCLH_00179 6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CMAJJCLH_00180 1e-87 S Alpha beta hydrolase
CMAJJCLH_00181 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMAJJCLH_00182 1.2e-140 V MatE
CMAJJCLH_00183 2.6e-155 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
CMAJJCLH_00184 2.4e-65 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMAJJCLH_00185 1.3e-96 V ABC transporter
CMAJJCLH_00186 1.6e-131 bacI V MacB-like periplasmic core domain
CMAJJCLH_00187 9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMAJJCLH_00188 1.7e-26
CMAJJCLH_00189 2.1e-180 yhdP S Transporter associated domain
CMAJJCLH_00190 2.7e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
CMAJJCLH_00191 0.0 L Helicase C-terminal domain protein
CMAJJCLH_00192 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMAJJCLH_00193 3.7e-212 yfnA E Amino Acid
CMAJJCLH_00194 2.4e-53 zur P Belongs to the Fur family
CMAJJCLH_00195 3.1e-09 3.2.1.14 GH18
CMAJJCLH_00196 5e-98
CMAJJCLH_00197 1.3e-09
CMAJJCLH_00198 3.3e-103 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMAJJCLH_00199 1.5e-99 glnH ET ABC transporter
CMAJJCLH_00200 1.2e-85 gluC P ABC transporter permease
CMAJJCLH_00201 9.6e-78 glnP P ABC transporter permease
CMAJJCLH_00204 7.9e-29 S Replication initiator protein A (RepA) N-terminus
CMAJJCLH_00205 3.1e-13
CMAJJCLH_00206 7.2e-18 gepA S Protein of unknown function (DUF4065)
CMAJJCLH_00209 9.9e-32 S RRXRR protein
CMAJJCLH_00212 1.9e-110 3.1.21.3 V N-6 DNA Methylase
CMAJJCLH_00213 2.5e-48 3.1.21.3 L N-6 DNA Methylase
CMAJJCLH_00214 1.2e-40 L Helix-turn-helix domain
CMAJJCLH_00216 6.4e-69 soj D CobQ CobB MinD ParA nucleotide binding domain protein
CMAJJCLH_00217 6.2e-33 ybl78 L Conserved phage C-terminus (Phg_2220_C)
CMAJJCLH_00218 3.7e-123 dnaB 3.6.4.12 L DnaB-like helicase C terminal domain
CMAJJCLH_00221 6e-66 S RRXRR protein
CMAJJCLH_00224 5.1e-65 floL S SPFH domain / Band 7 family
CMAJJCLH_00227 2.8e-17
CMAJJCLH_00229 1.7e-31 lytE M Lysin motif
CMAJJCLH_00232 2.5e-21 ftsK D FtsK SpoIIIE family protein
CMAJJCLH_00235 6.3e-20 infB M YSIRK type signal peptide
CMAJJCLH_00236 2.1e-102 L Belongs to the 'phage' integrase family
CMAJJCLH_00237 1.6e-10 sdrF M domain protein
CMAJJCLH_00238 1.8e-12 yajC U Preprotein translocase
CMAJJCLH_00239 5.6e-206 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CMAJJCLH_00240 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CMAJJCLH_00241 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CMAJJCLH_00242 5.6e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CMAJJCLH_00243 5.4e-225 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CMAJJCLH_00244 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CMAJJCLH_00245 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
CMAJJCLH_00246 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMAJJCLH_00247 7.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMAJJCLH_00248 2.9e-64 ymfM S Helix-turn-helix domain
CMAJJCLH_00249 2.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
CMAJJCLH_00250 2.4e-149 ymfH S Peptidase M16
CMAJJCLH_00251 1.6e-108 ymfF S Peptidase M16 inactive domain protein
CMAJJCLH_00252 1.3e-283 ftsK D Belongs to the FtsK SpoIIIE SftA family
CMAJJCLH_00253 2.2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CMAJJCLH_00254 9.2e-99 rrmA 2.1.1.187 H Methyltransferase
CMAJJCLH_00255 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMAJJCLH_00256 8.1e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CMAJJCLH_00257 4.2e-21 cutC P Participates in the control of copper homeostasis
CMAJJCLH_00258 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
CMAJJCLH_00259 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
CMAJJCLH_00260 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMAJJCLH_00261 5.3e-68 ybbR S YbbR-like protein
CMAJJCLH_00262 2.9e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CMAJJCLH_00263 2.4e-71 S Protein of unknown function (DUF1361)
CMAJJCLH_00264 2.1e-115 murB 1.3.1.98 M Cell wall formation
CMAJJCLH_00265 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
CMAJJCLH_00266 8.4e-57 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
CMAJJCLH_00267 2.6e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CMAJJCLH_00268 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CMAJJCLH_00269 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
CMAJJCLH_00270 3.1e-42 yxjI
CMAJJCLH_00271 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CMAJJCLH_00272 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CMAJJCLH_00273 2.8e-19 secG U Preprotein translocase
CMAJJCLH_00274 9.2e-180 clcA P chloride
CMAJJCLH_00276 8.5e-19 S protein disulfide oxidoreductase activity
CMAJJCLH_00284 5.8e-31
CMAJJCLH_00286 1.1e-50 Q DNA (cytosine-5-)-methyltransferase activity
CMAJJCLH_00292 2.3e-99 O ATPase family associated with various cellular activities (AAA)
CMAJJCLH_00295 1.1e-132 L transposase, IS605 OrfB family
CMAJJCLH_00303 3.9e-40
CMAJJCLH_00306 5.1e-60 3.1.3.16, 3.1.4.37 T AAA domain
CMAJJCLH_00311 1.9e-32 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMAJJCLH_00320 9.9e-49 M Prophage endopeptidase tail
CMAJJCLH_00327 3e-124 yvgN C Aldo keto reductase
CMAJJCLH_00328 3e-105 yraQ S Predicted permease
CMAJJCLH_00329 6.9e-62 yeeE S Sulphur transport
CMAJJCLH_00330 2e-16 yeeD O Belongs to the sulfur carrier protein TusA family
CMAJJCLH_00331 3.2e-115 ynjE 2.8.1.11 P Rhodanese Homology Domain
CMAJJCLH_00333 9.5e-235 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
CMAJJCLH_00334 3.2e-26 S Psort location Cytoplasmic, score
CMAJJCLH_00335 5.8e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
CMAJJCLH_00336 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
CMAJJCLH_00337 4.7e-73 prdD S An automated process has identified a potential problem with this gene model
CMAJJCLH_00338 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
CMAJJCLH_00339 7e-144 5.1.1.4 E Proline racemase
CMAJJCLH_00340 4.4e-94 XK27_00825 S Sulfite exporter TauE/SafE
CMAJJCLH_00341 5.3e-223 ybeC E amino acid
CMAJJCLH_00342 9e-49 yedF O Belongs to the sulfur carrier protein TusA family
CMAJJCLH_00343 4.5e-08 S Protein of unknown function (DUF3343)
CMAJJCLH_00344 2e-136 selB J Elongation factor SelB, winged helix
CMAJJCLH_00345 5.1e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
CMAJJCLH_00346 2.4e-110 selA 2.9.1.1 H Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
CMAJJCLH_00347 9e-29 yitW S Iron-sulfur cluster assembly protein
CMAJJCLH_00348 2.6e-175 rnfC C RnfC Barrel sandwich hybrid domain
CMAJJCLH_00349 2.7e-100 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
CMAJJCLH_00350 7.1e-148 yedE S Sulphur transport
CMAJJCLH_00351 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
CMAJJCLH_00352 6.4e-16 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
CMAJJCLH_00353 3.1e-57 yvbG U MarC family integral membrane protein
CMAJJCLH_00354 1.3e-180 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
CMAJJCLH_00355 3.8e-50 S Membrane
CMAJJCLH_00356 1.1e-75 rhaR K helix_turn_helix, arabinose operon control protein
CMAJJCLH_00357 1.5e-188 iolF EGP Major facilitator Superfamily
CMAJJCLH_00358 7.5e-216 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
CMAJJCLH_00359 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
CMAJJCLH_00360 2.2e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
CMAJJCLH_00361 3.4e-109 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
CMAJJCLH_00362 6.6e-157 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CMAJJCLH_00363 1.3e-190 XK27_11280 S Psort location CytoplasmicMembrane, score
CMAJJCLH_00365 1.4e-88 L Belongs to the 'phage' integrase family
CMAJJCLH_00366 1e-54 tlpA2 L Transposase IS200 like
CMAJJCLH_00368 2.2e-204 G PTS system Galactitol-specific IIC component
CMAJJCLH_00369 2e-93 M Exporter of polyketide antibiotics
CMAJJCLH_00370 9.5e-48 M Exporter of polyketide antibiotics
CMAJJCLH_00371 8.9e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
CMAJJCLH_00372 5.4e-44 S Repeat protein
CMAJJCLH_00373 2.8e-279 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CMAJJCLH_00374 3.4e-115 L Belongs to the 'phage' integrase family
CMAJJCLH_00375 7.9e-14
CMAJJCLH_00377 1.3e-26 ligA 2.7.7.7, 6.5.1.2 L EXOIII
CMAJJCLH_00378 1.5e-13
CMAJJCLH_00379 3.2e-16 L nuclease
CMAJJCLH_00380 1e-27 S Short C-terminal domain
CMAJJCLH_00382 3.8e-38 E Zn peptidase
CMAJJCLH_00383 4.1e-37 K Helix-turn-helix XRE-family like proteins
CMAJJCLH_00384 5.9e-10 XK27_07105 K Helix-turn-helix XRE-family like proteins
CMAJJCLH_00385 8.2e-19 S Domain of unknown function (DUF771)
CMAJJCLH_00390 3.6e-54 S Putative HNHc nuclease
CMAJJCLH_00391 4e-32 L N-terminal phage replisome organiser (Phage_rep_org_N)
CMAJJCLH_00394 1.6e-25
CMAJJCLH_00395 9.7e-71
CMAJJCLH_00398 2.2e-36 L recombinase activity
CMAJJCLH_00411 1.5e-27 arpU S Phage transcriptional regulator, ArpU family
CMAJJCLH_00414 1.6e-21
CMAJJCLH_00415 9.5e-89 L HNH nucleases
CMAJJCLH_00416 4.3e-83 L Phage terminase, small subunit
CMAJJCLH_00417 0.0 S Phage Terminase
CMAJJCLH_00419 4.7e-208 S Phage portal protein
CMAJJCLH_00420 1.2e-118 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
CMAJJCLH_00421 1.2e-222 S Phage capsid family
CMAJJCLH_00422 4.8e-22 S Phage gp6-like head-tail connector protein
CMAJJCLH_00423 2.9e-60 S Phage head-tail joining protein
CMAJJCLH_00424 1.1e-65 S Bacteriophage HK97-gp10, putative tail-component
CMAJJCLH_00425 2.7e-64 S Protein of unknown function (DUF806)
CMAJJCLH_00426 5.5e-124 S Phage tail tube protein
CMAJJCLH_00427 6.3e-54 S Phage tail assembly chaperone proteins, TAC
CMAJJCLH_00430 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMAJJCLH_00431 1e-45 comFC S Competence protein
CMAJJCLH_00432 5.4e-128 comFA L Helicase C-terminal domain protein
CMAJJCLH_00433 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
CMAJJCLH_00434 1.4e-296 ydaO E amino acid
CMAJJCLH_00435 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
CMAJJCLH_00436 1.8e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CMAJJCLH_00437 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMAJJCLH_00438 3.1e-33 S CAAX protease self-immunity
CMAJJCLH_00439 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CMAJJCLH_00440 1.2e-253 uup S ABC transporter, ATP-binding protein
CMAJJCLH_00441 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMAJJCLH_00442 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
CMAJJCLH_00443 3.7e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
CMAJJCLH_00444 2.7e-140 ansA 3.5.1.1 EJ Asparaginase
CMAJJCLH_00445 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
CMAJJCLH_00446 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMAJJCLH_00447 1.4e-40 yabA L Involved in initiation control of chromosome replication
CMAJJCLH_00448 2.3e-83 holB 2.7.7.7 L DNA polymerase III
CMAJJCLH_00449 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CMAJJCLH_00450 9.2e-29 yaaL S Protein of unknown function (DUF2508)
CMAJJCLH_00451 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMAJJCLH_00452 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CMAJJCLH_00453 1.5e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMAJJCLH_00454 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CMAJJCLH_00455 1.9e-75 rsmC 2.1.1.172 J Methyltransferase
CMAJJCLH_00456 2.7e-27 nrdH O Glutaredoxin
CMAJJCLH_00457 9.7e-46 nrdI F NrdI Flavodoxin like
CMAJJCLH_00458 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMAJJCLH_00459 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMAJJCLH_00460 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMAJJCLH_00461 1.4e-54
CMAJJCLH_00462 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CMAJJCLH_00463 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CMAJJCLH_00464 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CMAJJCLH_00465 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMAJJCLH_00466 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
CMAJJCLH_00467 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CMAJJCLH_00468 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CMAJJCLH_00469 9.2e-104 tatD L hydrolase, TatD family
CMAJJCLH_00470 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CMAJJCLH_00471 7e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CMAJJCLH_00472 1.2e-22 veg S Biofilm formation stimulator VEG
CMAJJCLH_00473 8e-90 S Alpha/beta hydrolase of unknown function (DUF915)
CMAJJCLH_00474 1.7e-138 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
CMAJJCLH_00475 2.8e-47 argR K Regulates arginine biosynthesis genes
CMAJJCLH_00476 9e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CMAJJCLH_00477 3e-155 amtB P ammonium transporter
CMAJJCLH_00478 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
CMAJJCLH_00479 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CMAJJCLH_00480 2.9e-149 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
CMAJJCLH_00481 2.9e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMAJJCLH_00482 1.2e-103 pfoS S Phosphotransferase system, EIIC
CMAJJCLH_00484 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMAJJCLH_00485 2.5e-44 adhR K helix_turn_helix, mercury resistance
CMAJJCLH_00486 5.2e-137 purR 2.4.2.7 F pur operon repressor
CMAJJCLH_00487 1.5e-47 EGP Transmembrane secretion effector
CMAJJCLH_00488 5.1e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CMAJJCLH_00489 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMAJJCLH_00490 1.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CMAJJCLH_00492 5.8e-112 dkg S reductase
CMAJJCLH_00493 1.3e-24
CMAJJCLH_00494 4.6e-61 L Resolvase, N-terminal domain
CMAJJCLH_00495 5.3e-99 L Probable transposase
CMAJJCLH_00496 1e-78 2.4.2.3 F Phosphorylase superfamily
CMAJJCLH_00497 1.4e-290 ybiT S ABC transporter, ATP-binding protein
CMAJJCLH_00498 1.5e-62 bCE_4747 S Beta-lactamase superfamily domain
CMAJJCLH_00499 3.5e-100 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CMAJJCLH_00500 3e-124 S overlaps another CDS with the same product name
CMAJJCLH_00501 2.9e-86 S overlaps another CDS with the same product name
CMAJJCLH_00503 1.4e-56 spoVK O ATPase family associated with various cellular activities (AAA)
CMAJJCLH_00504 6.9e-23
CMAJJCLH_00505 4.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
CMAJJCLH_00507 3.1e-73
CMAJJCLH_00508 2.8e-22
CMAJJCLH_00509 4.2e-103 ydcZ S Putative inner membrane exporter, YdcZ
CMAJJCLH_00510 5.8e-88 S hydrolase
CMAJJCLH_00511 3.3e-205 ywfO S HD domain protein
CMAJJCLH_00512 1.3e-85 yfeJ 6.3.5.2 F glutamine amidotransferase
CMAJJCLH_00513 9.5e-58 tlpA2 L Transposase IS200 like
CMAJJCLH_00514 1.1e-159 L transposase, IS605 OrfB family
CMAJJCLH_00515 2.7e-30 P Heavy-metal-associated domain
CMAJJCLH_00516 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
CMAJJCLH_00521 1.9e-07 L Resolvase, N terminal domain
CMAJJCLH_00522 3.1e-33 L Resolvase, N terminal domain
CMAJJCLH_00523 2.3e-33 S Phage derived protein Gp49-like (DUF891)
CMAJJCLH_00524 2.4e-25 K Helix-turn-helix domain
CMAJJCLH_00525 1.1e-94 cadD P Cadmium resistance transporter
CMAJJCLH_00526 1.9e-56 cadX K Bacterial regulatory protein, arsR family
CMAJJCLH_00527 1.9e-74 K Copper transport repressor CopY TcrY
CMAJJCLH_00528 2e-142 copB 3.6.3.4 P P-type ATPase
CMAJJCLH_00529 3.2e-195 copB 3.6.3.4 P P-type ATPase
CMAJJCLH_00531 2.2e-50
CMAJJCLH_00532 1.9e-26 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMAJJCLH_00533 1.3e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CMAJJCLH_00534 1.1e-142 xerS L Phage integrase family
CMAJJCLH_00538 1e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
CMAJJCLH_00539 1.6e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
CMAJJCLH_00540 2.2e-76 desR K helix_turn_helix, Lux Regulon
CMAJJCLH_00541 5.4e-57 desK 2.7.13.3 T Histidine kinase
CMAJJCLH_00542 2.4e-53 yvfS V ABC-2 type transporter
CMAJJCLH_00543 4.7e-80 yvfR V ABC transporter
CMAJJCLH_00544 3.5e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CMAJJCLH_00545 2.9e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CMAJJCLH_00546 1.9e-29
CMAJJCLH_00547 9.1e-47 sip L Belongs to the 'phage' integrase family
CMAJJCLH_00550 2.5e-29 M CHAP domain
CMAJJCLH_00552 2.2e-191 U type IV secretory pathway VirB4
CMAJJCLH_00553 3.5e-27
CMAJJCLH_00555 6e-77
CMAJJCLH_00556 7.6e-220 U TraM recognition site of TraD and TraG
CMAJJCLH_00560 2.2e-148 clpB O Belongs to the ClpA ClpB family
CMAJJCLH_00563 9.9e-167 topA2 5.99.1.2 G Topoisomerase IA
CMAJJCLH_00564 5.7e-41 L Protein of unknown function (DUF3991)
CMAJJCLH_00565 7.7e-69
CMAJJCLH_00567 5.2e-90 pac DM Glucan-binding protein C
CMAJJCLH_00569 3.8e-13 infB M YSIRK type signal peptide
CMAJJCLH_00570 1.2e-105 L Belongs to the 'phage' integrase family
CMAJJCLH_00571 2e-08
CMAJJCLH_00572 1.3e-25 D nuclear chromosome segregation
CMAJJCLH_00574 1.7e-78 S Fic/DOC family
CMAJJCLH_00575 3.4e-29 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
CMAJJCLH_00576 3.3e-12 chpR T PFAM SpoVT AbrB
CMAJJCLH_00577 4.6e-43
CMAJJCLH_00578 8e-40 gepA S Protein of unknown function (DUF4065)
CMAJJCLH_00579 3.7e-59 ruvB 3.6.4.12 L four-way junction helicase activity
CMAJJCLH_00583 1.3e-12 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
CMAJJCLH_00584 9.8e-20
CMAJJCLH_00587 2.7e-07
CMAJJCLH_00592 7.6e-21 S Replication initiator protein A (RepA) N-terminus
CMAJJCLH_00603 2.3e-11 3.4.21.88 K Peptidase S24-like
CMAJJCLH_00604 6.6e-11 S sequence-specific DNA binding
CMAJJCLH_00605 4e-89 plsC 2.3.1.51 I Acyltransferase
CMAJJCLH_00606 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
CMAJJCLH_00607 1.5e-27 yazA L GIY-YIG catalytic domain protein
CMAJJCLH_00608 7.2e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
CMAJJCLH_00609 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMAJJCLH_00610 7.4e-81 sip L Belongs to the 'phage' integrase family
CMAJJCLH_00611 1.9e-20
CMAJJCLH_00612 8e-14 S Pfam:DUF955
CMAJJCLH_00613 3e-19 K Helix-turn-helix domain
CMAJJCLH_00616 1.5e-117 K Phage regulatory protein
CMAJJCLH_00619 2.3e-18
CMAJJCLH_00620 5.8e-30 S Uncharacterized protein conserved in bacteria (DUF2188)
CMAJJCLH_00621 1.4e-14 K Cro/C1-type HTH DNA-binding domain
CMAJJCLH_00625 2e-77 S Siphovirus Gp157
CMAJJCLH_00626 1.8e-240 res L Helicase C-terminal domain protein
CMAJJCLH_00627 1.6e-116 L AAA domain
CMAJJCLH_00628 6.9e-84
CMAJJCLH_00629 2.8e-140 S Bifunctional DNA primase/polymerase, N-terminal
CMAJJCLH_00630 3e-229 S Virulence-associated protein E
CMAJJCLH_00631 1.2e-49 S VRR_NUC
CMAJJCLH_00636 1e-11 arpU S Phage transcriptional regulator, ArpU family
CMAJJCLH_00638 1.3e-31
CMAJJCLH_00639 3.4e-167 S Terminase RNAseH like domain
CMAJJCLH_00640 9.6e-145 S Phage portal protein, SPP1 Gp6-like
CMAJJCLH_00641 6.2e-96 S Phage minor capsid protein 2
CMAJJCLH_00643 2.7e-20 S Phage minor structural protein GP20
CMAJJCLH_00644 2.5e-97 S T=7 icosahedral viral capsid
CMAJJCLH_00645 5.2e-15
CMAJJCLH_00646 6.7e-30 S Minor capsid protein
CMAJJCLH_00647 7.9e-16 S Minor capsid protein
CMAJJCLH_00648 7.6e-17 S Minor capsid protein from bacteriophage
CMAJJCLH_00649 7.5e-38 N domain, Protein
CMAJJCLH_00651 6.3e-39 S Bacteriophage Gp15 protein
CMAJJCLH_00652 5e-106 M Phage tail tape measure protein TP901
CMAJJCLH_00653 1.3e-60 S Phage tail protein
CMAJJCLH_00654 2.4e-102 M Prophage endopeptidase tail
CMAJJCLH_00655 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMAJJCLH_00656 5.6e-127
CMAJJCLH_00657 5.1e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CMAJJCLH_00658 1.6e-42 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
CMAJJCLH_00659 2.3e-31 K Transcriptional regulator
CMAJJCLH_00660 2e-104 ybhR V ABC transporter
CMAJJCLH_00661 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
CMAJJCLH_00662 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CMAJJCLH_00663 8.8e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMAJJCLH_00664 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMAJJCLH_00665 2.2e-270 helD 3.6.4.12 L DNA helicase
CMAJJCLH_00667 1.3e-114 htpX O Belongs to the peptidase M48B family
CMAJJCLH_00668 8.7e-72 lemA S LemA family
CMAJJCLH_00669 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
CMAJJCLH_00670 3.2e-45 yjcF K protein acetylation
CMAJJCLH_00672 3.9e-254 yfiC V ABC transporter
CMAJJCLH_00673 9.9e-223 lmrA V ABC transporter, ATP-binding protein
CMAJJCLH_00674 5.8e-35 K Bacterial regulatory proteins, tetR family
CMAJJCLH_00675 9.5e-246 yhcA V ABC transporter, ATP-binding protein
CMAJJCLH_00676 2.6e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CMAJJCLH_00677 1e-146 G Transporter, major facilitator family protein
CMAJJCLH_00678 5.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
CMAJJCLH_00679 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
CMAJJCLH_00680 2.5e-113 K response regulator
CMAJJCLH_00681 3.4e-89 patB 4.4.1.8 E Aminotransferase, class I
CMAJJCLH_00682 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CMAJJCLH_00683 3.1e-30 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CMAJJCLH_00684 1.5e-111 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMAJJCLH_00685 1.9e-190 glnPH2 P ABC transporter permease
CMAJJCLH_00686 6.4e-213 yjeM E Amino Acid
CMAJJCLH_00687 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
CMAJJCLH_00688 1.5e-137 tetA EGP Major facilitator Superfamily
CMAJJCLH_00689 1e-62 S Glycosyltransferase like family 2
CMAJJCLH_00690 8.4e-116 cps1D M Domain of unknown function (DUF4422)
CMAJJCLH_00691 9.5e-38 S CAAX protease self-immunity
CMAJJCLH_00692 9.1e-89 yvyE 3.4.13.9 S YigZ family
CMAJJCLH_00693 3.3e-57 S Haloacid dehalogenase-like hydrolase
CMAJJCLH_00694 5.8e-154 EGP Major facilitator Superfamily
CMAJJCLH_00696 6.5e-66 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CMAJJCLH_00697 2.7e-27 K helix_turn_helix, mercury resistance
CMAJJCLH_00698 5.8e-90 S NADPH-dependent FMN reductase
CMAJJCLH_00699 2e-101 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CMAJJCLH_00700 1.5e-55 S ECF transporter, substrate-specific component
CMAJJCLH_00701 2.8e-95 znuB U ABC 3 transport family
CMAJJCLH_00702 7.7e-99 fhuC P ABC transporter
CMAJJCLH_00703 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
CMAJJCLH_00704 1.8e-59 V Abi-like protein
CMAJJCLH_00705 3.4e-38
CMAJJCLH_00706 1.2e-13 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
CMAJJCLH_00707 2.5e-53 XK27_01040 S Protein of unknown function (DUF1129)
CMAJJCLH_00708 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CMAJJCLH_00709 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
CMAJJCLH_00710 4.1e-108 spo0J K Belongs to the ParB family
CMAJJCLH_00711 6.5e-118 soj D Sporulation initiation inhibitor
CMAJJCLH_00712 7e-81 noc K Belongs to the ParB family
CMAJJCLH_00713 4.7e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
CMAJJCLH_00714 1.6e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CMAJJCLH_00715 1.5e-108 3.1.4.46 C phosphodiesterase
CMAJJCLH_00716 0.0 pacL 3.6.3.8 P P-type ATPase
CMAJJCLH_00717 1.8e-48 alkD L DNA alkylation repair enzyme
CMAJJCLH_00718 3.8e-136 EG EamA-like transporter family
CMAJJCLH_00719 3.6e-150 S Tetratricopeptide repeat protein
CMAJJCLH_00720 3.4e-204 hisS 6.1.1.21 J histidyl-tRNA synthetase
CMAJJCLH_00721 8.7e-299 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CMAJJCLH_00722 7e-127 corA P CorA-like Mg2+ transporter protein
CMAJJCLH_00723 1.1e-160 nhaC C Na H antiporter NhaC
CMAJJCLH_00724 4.2e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CMAJJCLH_00725 7.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
CMAJJCLH_00727 4.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMAJJCLH_00728 1.2e-155 iscS 2.8.1.7 E Aminotransferase class V
CMAJJCLH_00729 3.7e-41 XK27_04120 S Putative amino acid metabolism
CMAJJCLH_00730 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CMAJJCLH_00731 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CMAJJCLH_00732 4.3e-15 S Protein of unknown function (DUF2929)
CMAJJCLH_00733 0.0 dnaE 2.7.7.7 L DNA polymerase
CMAJJCLH_00734 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CMAJJCLH_00735 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CMAJJCLH_00737 1e-39 ypaA S Protein of unknown function (DUF1304)
CMAJJCLH_00738 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMAJJCLH_00739 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMAJJCLH_00740 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMAJJCLH_00747 5.1e-08
CMAJJCLH_00753 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
CMAJJCLH_00754 9.2e-48 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CMAJJCLH_00755 1.2e-67 coiA 3.6.4.12 S Competence protein
CMAJJCLH_00756 9.6e-232 pepF E oligoendopeptidase F
CMAJJCLH_00757 3.9e-41 yjbH Q Thioredoxin
CMAJJCLH_00758 1.4e-97 pstS P Phosphate
CMAJJCLH_00759 5.4e-119 pstC P probably responsible for the translocation of the substrate across the membrane
CMAJJCLH_00760 3e-122 pstA P Phosphate transport system permease protein PstA
CMAJJCLH_00761 1e-113 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMAJJCLH_00762 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMAJJCLH_00763 2.7e-56 P Plays a role in the regulation of phosphate uptake
CMAJJCLH_00764 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
CMAJJCLH_00765 1.1e-79 S VIT family
CMAJJCLH_00766 9.4e-84 S membrane
CMAJJCLH_00767 2.8e-40 M1-874 K Domain of unknown function (DUF1836)
CMAJJCLH_00768 2.3e-65 hly S protein, hemolysin III
CMAJJCLH_00769 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
CMAJJCLH_00770 4.5e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMAJJCLH_00773 3e-14
CMAJJCLH_00774 5.1e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CMAJJCLH_00775 1.3e-158 ccpA K catabolite control protein A
CMAJJCLH_00776 3.7e-42 S VanZ like family
CMAJJCLH_00777 4.3e-119 yebC K Transcriptional regulatory protein
CMAJJCLH_00778 1e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMAJJCLH_00779 1.1e-120 comGA NU Type II IV secretion system protein
CMAJJCLH_00780 8.8e-99 comGB NU type II secretion system
CMAJJCLH_00781 7.9e-27 comGC U competence protein ComGC
CMAJJCLH_00782 1.5e-13
CMAJJCLH_00784 4.1e-11 S Putative Competence protein ComGF
CMAJJCLH_00789 5.4e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CMAJJCLH_00790 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CMAJJCLH_00791 5.1e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMAJJCLH_00792 1.6e-160 camS S sex pheromone
CMAJJCLH_00793 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMAJJCLH_00794 2.3e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CMAJJCLH_00795 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMAJJCLH_00796 9.8e-146 yegS 2.7.1.107 G Lipid kinase
CMAJJCLH_00797 3.4e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMAJJCLH_00798 3.7e-122 L Mrr N-terminal domain
CMAJJCLH_00799 2.1e-17
CMAJJCLH_00800 0.0 2.1.1.72 V type I restriction-modification system
CMAJJCLH_00801 6.4e-70 hsdS 3.1.21.3 V COG0732 Restriction endonuclease S subunits
CMAJJCLH_00802 0.0 hsdR 3.1.21.3 L COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
CMAJJCLH_00803 2.1e-07
CMAJJCLH_00804 1.9e-233 L AAA ATPase domain
CMAJJCLH_00805 8.6e-151 3.6.4.12 L UvrD/REP helicase N-terminal domain
CMAJJCLH_00806 2.1e-56 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
CMAJJCLH_00807 7e-26 S Domain of unknown function (DUF3841)
CMAJJCLH_00808 2.2e-87 spoVK O ATPase family associated with various cellular activities (AAA)
CMAJJCLH_00809 2.5e-155 nrnB S DHHA1 domain
CMAJJCLH_00810 3.7e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CMAJJCLH_00811 1.7e-59
CMAJJCLH_00812 5e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
CMAJJCLH_00813 1.6e-22 S Cytochrome B5
CMAJJCLH_00814 2.3e-19 sigH K DNA-templated transcription, initiation
CMAJJCLH_00815 7.6e-69 recX 2.4.1.337 GT4 S Regulatory protein RecX
CMAJJCLH_00816 8.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMAJJCLH_00817 2.6e-97 ygaC J Belongs to the UPF0374 family
CMAJJCLH_00818 5.3e-92 yueF S AI-2E family transporter
CMAJJCLH_00819 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CMAJJCLH_00820 2.3e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CMAJJCLH_00821 9.8e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CMAJJCLH_00822 0.0 lacL 3.2.1.23 G -beta-galactosidase
CMAJJCLH_00823 8.9e-289 lacS G Transporter
CMAJJCLH_00824 7.7e-111 galR K Transcriptional regulator
CMAJJCLH_00825 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CMAJJCLH_00826 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CMAJJCLH_00827 1.4e-201 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CMAJJCLH_00828 0.0 rafA 3.2.1.22 G alpha-galactosidase
CMAJJCLH_00829 1.7e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
CMAJJCLH_00830 2.1e-21 XK27_09445 S Domain of unknown function (DUF1827)
CMAJJCLH_00837 2.1e-07
CMAJJCLH_00847 2.1e-176 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMAJJCLH_00848 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMAJJCLH_00849 2.4e-192 cycA E Amino acid permease
CMAJJCLH_00850 6.4e-187 ytgP S Polysaccharide biosynthesis protein
CMAJJCLH_00851 2.5e-63 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMAJJCLH_00852 4.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMAJJCLH_00853 6.6e-193 pepV 3.5.1.18 E dipeptidase PepV
CMAJJCLH_00854 7.4e-182 S Protein of unknown function DUF262
CMAJJCLH_00856 3e-36
CMAJJCLH_00857 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CMAJJCLH_00858 4.2e-61 marR K Transcriptional regulator, MarR family
CMAJJCLH_00859 1.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMAJJCLH_00860 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMAJJCLH_00861 5.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CMAJJCLH_00862 1.1e-98 IQ reductase
CMAJJCLH_00863 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CMAJJCLH_00864 1.7e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CMAJJCLH_00865 1e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CMAJJCLH_00866 4.2e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
CMAJJCLH_00867 8e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CMAJJCLH_00868 5.1e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
CMAJJCLH_00869 7.1e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
CMAJJCLH_00870 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CMAJJCLH_00871 3.1e-30 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CMAJJCLH_00872 1.9e-09 3.2.1.18 GH33 M Rib/alpha-like repeat
CMAJJCLH_00874 8.6e-81 L hmm pf00665
CMAJJCLH_00875 1.4e-10 L Helix-turn-helix domain
CMAJJCLH_00877 2.5e-08 L Helix-turn-helix domain
CMAJJCLH_00878 1.8e-151 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CMAJJCLH_00879 9e-34 yxaB 2.4.1.166 GT2 M Glycosyltransferase like family 2
CMAJJCLH_00880 7.3e-109 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CMAJJCLH_00881 2e-66 nss M transferase activity, transferring glycosyl groups
CMAJJCLH_00882 1.4e-07 M Glycosyltransferase like family 2
CMAJJCLH_00883 1.1e-18 arbx M family 8
CMAJJCLH_00885 3.5e-55 nss M transferase activity, transferring glycosyl groups
CMAJJCLH_00886 8.7e-37 M Glycosyl transferase family 8
CMAJJCLH_00887 1.1e-69 nss M transferase activity, transferring glycosyl groups
CMAJJCLH_00888 2.4e-31 M Glycosyltransferase like family 2
CMAJJCLH_00890 1.4e-38 arbx M family 8
CMAJJCLH_00891 9.4e-149 mepA V MATE efflux family protein
CMAJJCLH_00892 7e-153 lsa S ABC transporter
CMAJJCLH_00893 6.8e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMAJJCLH_00894 5.2e-109 puuD S peptidase C26
CMAJJCLH_00895 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
CMAJJCLH_00896 1.1e-25
CMAJJCLH_00897 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
CMAJJCLH_00898 1.1e-59 uspA T Universal stress protein family
CMAJJCLH_00899 2e-54 L PFAM Integrase catalytic region
CMAJJCLH_00900 5.7e-10 L HTH-like domain
CMAJJCLH_00901 5.5e-157 XK27_08315 M Sulfatase
CMAJJCLH_00902 4.1e-177 thrC 4.2.3.1 E Threonine synthase
CMAJJCLH_00903 6.9e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMAJJCLH_00904 2.6e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CMAJJCLH_00905 1.2e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CMAJJCLH_00906 2.2e-177 licA 2.7.1.89 M Choline/ethanolamine kinase
CMAJJCLH_00907 1.1e-84 M Nucleotidyl transferase
CMAJJCLH_00908 6.7e-151 M BCCT, betaine/carnitine/choline family transporter
CMAJJCLH_00909 2.6e-56 S peptidoglycan catabolic process
CMAJJCLH_00911 1.4e-167 mdtG EGP Major facilitator Superfamily
CMAJJCLH_00912 8.2e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
CMAJJCLH_00913 9.8e-84 treR K UTRA
CMAJJCLH_00914 9.5e-259 treB G phosphotransferase system
CMAJJCLH_00915 4.6e-63 3.1.3.73 G phosphoglycerate mutase
CMAJJCLH_00916 2.4e-82 pncA Q isochorismatase
CMAJJCLH_00917 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
CMAJJCLH_00918 4e-101 ydhQ K UbiC transcription regulator-associated domain protein
CMAJJCLH_00919 2.5e-170 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CMAJJCLH_00920 2.3e-26 K Transcriptional regulator, HxlR family
CMAJJCLH_00921 1.2e-42 3.6.4.12 S PD-(D/E)XK nuclease family transposase
CMAJJCLH_00933 1.9e-21 ssb L Single-stranded DNA-binding protein
CMAJJCLH_00934 1.5e-86 endA F DNA RNA non-specific endonuclease
CMAJJCLH_00935 5.6e-133 NU StbA protein
CMAJJCLH_00937 6.6e-08 S Uncharacterized protein pXO2-11
CMAJJCLH_00938 4.3e-40
CMAJJCLH_00939 3.8e-239 trsE S COG0433 Predicted ATPase
CMAJJCLH_00941 2.6e-60 M Peptidase family M23
CMAJJCLH_00944 1.5e-25 S Uncharacterised protein family (UPF0236)
CMAJJCLH_00945 1.3e-70 S Uncharacterised protein family (UPF0236)
CMAJJCLH_00946 1.8e-116 degV S EDD domain protein, DegV family
CMAJJCLH_00947 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
CMAJJCLH_00948 2.4e-40 6.3.3.2 S ASCH
CMAJJCLH_00949 5.7e-188 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMAJJCLH_00950 4.1e-81 yjjH S Calcineurin-like phosphoesterase
CMAJJCLH_00951 1.8e-95 EG EamA-like transporter family
CMAJJCLH_00952 4.2e-79 natB CP ABC-type Na efflux pump, permease component
CMAJJCLH_00953 9.6e-113 natA S Domain of unknown function (DUF4162)
CMAJJCLH_00954 1.5e-21 K Acetyltransferase (GNAT) domain
CMAJJCLH_00956 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMAJJCLH_00957 3.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CMAJJCLH_00958 1.6e-171 rpsA 1.17.7.4 J Ribosomal protein S1
CMAJJCLH_00959 3.7e-59 arsC 1.20.4.1 T Low molecular weight phosphatase family
CMAJJCLH_00960 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CMAJJCLH_00961 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMAJJCLH_00962 5.9e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
CMAJJCLH_00963 8.4e-218 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMAJJCLH_00964 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
CMAJJCLH_00965 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
CMAJJCLH_00966 1.3e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CMAJJCLH_00967 4.7e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CMAJJCLH_00968 2.3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMAJJCLH_00969 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
CMAJJCLH_00970 1.3e-82 lytH 3.5.1.28 M Ami_3
CMAJJCLH_00971 2.6e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CMAJJCLH_00972 7.7e-12 M Lysin motif
CMAJJCLH_00973 9.1e-129 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
CMAJJCLH_00974 1.6e-58 ypbB 5.1.3.1 S Helix-turn-helix domain
CMAJJCLH_00975 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
CMAJJCLH_00976 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
CMAJJCLH_00977 1.2e-119 ica2 GT2 M Glycosyl transferase family group 2
CMAJJCLH_00978 4.8e-44
CMAJJCLH_00979 4.2e-92 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CMAJJCLH_00981 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CMAJJCLH_00982 5.8e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CMAJJCLH_00983 2.5e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CMAJJCLH_00984 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CMAJJCLH_00985 7.6e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
CMAJJCLH_00986 4.4e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMAJJCLH_00988 2.3e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
CMAJJCLH_00989 3.7e-56 3.6.1.27 I Acid phosphatase homologues
CMAJJCLH_00990 1.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
CMAJJCLH_00991 9.7e-74 2.3.1.178 M GNAT acetyltransferase
CMAJJCLH_00996 1.1e-10
CMAJJCLH_00997 5.6e-41
CMAJJCLH_00998 1.4e-16 S Bacterial toxin of type II toxin-antitoxin system, YafQ
CMAJJCLH_00999 1.3e-14
CMAJJCLH_01000 6.3e-302
CMAJJCLH_01001 4.9e-128 3.1.21.4 L Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1
CMAJJCLH_01002 3.3e-94 dam 2.1.1.72 L Site-specific DNA-methyltransferase (Adenine-specific)
CMAJJCLH_01004 2.3e-08 XK27_10540 S ParE toxin of type II toxin-antitoxin system, parDE
CMAJJCLH_01005 7.6e-09 D Antitoxin component of a toxin-antitoxin (TA) module
CMAJJCLH_01006 1.9e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
CMAJJCLH_01007 3.9e-64 ypsA S Belongs to the UPF0398 family
CMAJJCLH_01008 3.7e-188 nhaC C Na H antiporter NhaC
CMAJJCLH_01009 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CMAJJCLH_01010 8.4e-294 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
CMAJJCLH_01011 3.6e-112 xerD D recombinase XerD
CMAJJCLH_01012 4.8e-125 cvfB S S1 domain
CMAJJCLH_01013 4.1e-51 yeaL S Protein of unknown function (DUF441)
CMAJJCLH_01014 3.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CMAJJCLH_01015 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMAJJCLH_01016 3.2e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CMAJJCLH_01017 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CMAJJCLH_01018 3.5e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMAJJCLH_01019 2.9e-217 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CMAJJCLH_01020 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CMAJJCLH_01021 7.9e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
CMAJJCLH_01022 2.5e-177 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CMAJJCLH_01023 3.1e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
CMAJJCLH_01024 2e-70
CMAJJCLH_01026 3.7e-12
CMAJJCLH_01027 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CMAJJCLH_01028 1e-27 ysxB J Cysteine protease Prp
CMAJJCLH_01029 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
CMAJJCLH_01032 4.7e-71 S RRXRR protein
CMAJJCLH_01033 1e-198 L transposition, DNA-mediated
CMAJJCLH_01034 9.4e-94 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
CMAJJCLH_01035 1.1e-70 xerD L Phage integrase, N-terminal SAM-like domain
CMAJJCLH_01036 8.2e-266 fbp 3.1.3.11 G phosphatase activity
CMAJJCLH_01038 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CMAJJCLH_01039 3.6e-99 fabK 1.3.1.9 S Nitronate monooxygenase
CMAJJCLH_01040 3.1e-32 M Phage minor capsid protein 2
CMAJJCLH_01045 4.3e-07
CMAJJCLH_01047 2.1e-49 M Phage tail tape measure protein TP901
CMAJJCLH_01048 4e-110 IQ NAD dependent epimerase/dehydratase family
CMAJJCLH_01049 2.2e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
CMAJJCLH_01050 4.5e-43 gutM K Glucitol operon activator protein (GutM)
CMAJJCLH_01051 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
CMAJJCLH_01052 1.2e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
CMAJJCLH_01053 1.8e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
CMAJJCLH_01054 1.3e-64 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
CMAJJCLH_01056 1.6e-145 pbuO_1 S Permease family
CMAJJCLH_01057 2.1e-43 2.7.7.65 T GGDEF domain
CMAJJCLH_01058 9.5e-128 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
CMAJJCLH_01059 1.3e-183
CMAJJCLH_01060 7.6e-206 S Protein conserved in bacteria
CMAJJCLH_01061 1.2e-201 ydaM M Glycosyl transferase family group 2
CMAJJCLH_01062 0.0 ydaN S Bacterial cellulose synthase subunit
CMAJJCLH_01063 1.4e-113 2.7.7.65 T diguanylate cyclase activity
CMAJJCLH_01064 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
CMAJJCLH_01065 3.5e-38 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
CMAJJCLH_01067 0.0 rafA 3.2.1.22 G alpha-galactosidase
CMAJJCLH_01068 1.2e-53 S Membrane
CMAJJCLH_01069 2.6e-64 K helix_turn_helix, arabinose operon control protein
CMAJJCLH_01070 2.3e-45
CMAJJCLH_01071 3.4e-205 pipD E Dipeptidase
CMAJJCLH_01072 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CMAJJCLH_01073 2.6e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CMAJJCLH_01074 5.6e-60 speG J Acetyltransferase (GNAT) domain
CMAJJCLH_01075 2.3e-113 yitU 3.1.3.104 S hydrolase
CMAJJCLH_01076 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
CMAJJCLH_01077 4.8e-81
CMAJJCLH_01078 5.3e-179 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
CMAJJCLH_01079 1.1e-41 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
CMAJJCLH_01080 3.6e-14
CMAJJCLH_01081 4.9e-97 S Psort location CytoplasmicMembrane, score
CMAJJCLH_01082 1.1e-157 XK27_09615 S reductase
CMAJJCLH_01083 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
CMAJJCLH_01084 7.3e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CMAJJCLH_01085 6.2e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CMAJJCLH_01086 1.1e-309 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CMAJJCLH_01088 8.1e-154 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
CMAJJCLH_01089 2.9e-62 S Glycosyltransferase like family 2
CMAJJCLH_01090 2.5e-195 glf 5.4.99.9 M UDP-galactopyranose mutase
CMAJJCLH_01091 1.5e-38 S Acyltransferase family
CMAJJCLH_01092 2.6e-43 S Peptidase_C39 like family
CMAJJCLH_01093 2.5e-63 M Glycosyltransferase like family 2
CMAJJCLH_01094 3.7e-74 M LicD family
CMAJJCLH_01095 1.5e-57 cps3F
CMAJJCLH_01096 7.5e-93 M transferase activity, transferring glycosyl groups
CMAJJCLH_01097 2.8e-76 waaB GT4 M Glycosyl transferases group 1
CMAJJCLH_01098 2.4e-92 M Core-2/I-Branching enzyme
CMAJJCLH_01099 2.7e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CMAJJCLH_01100 6.2e-68 M Peptidase family M23
CMAJJCLH_01101 3e-69 ybhL S Belongs to the BI1 family
CMAJJCLH_01102 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
CMAJJCLH_01103 3.8e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CMAJJCLH_01104 1.3e-238 sftA D Belongs to the FtsK SpoIIIE SftA family
CMAJJCLH_01105 1.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMAJJCLH_01106 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CMAJJCLH_01107 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CMAJJCLH_01108 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
CMAJJCLH_01109 8.4e-72 ecsB U ABC transporter
CMAJJCLH_01110 9.8e-95 ecsA V ABC transporter, ATP-binding protein
CMAJJCLH_01111 7e-53 hit FG histidine triad
CMAJJCLH_01113 1.5e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CMAJJCLH_01114 7.3e-127 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
CMAJJCLH_01115 2e-21 yheA S Belongs to the UPF0342 family
CMAJJCLH_01116 1.5e-284 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CMAJJCLH_01117 1.7e-117 sip L Belongs to the 'phage' integrase family
CMAJJCLH_01118 8.9e-13 K Transcriptional regulator
CMAJJCLH_01119 9.1e-08 S Helix-turn-helix domain
CMAJJCLH_01120 4.4e-38 K COG3617 Prophage antirepressor
CMAJJCLH_01125 7.4e-20
CMAJJCLH_01127 1.7e-37 ybl78 L Conserved phage C-terminus (Phg_2220_C)
CMAJJCLH_01128 9.1e-08 arpU S Phage transcriptional regulator, ArpU family
CMAJJCLH_01130 4.4e-07
CMAJJCLH_01131 2.3e-16
CMAJJCLH_01134 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMAJJCLH_01135 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CMAJJCLH_01136 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMAJJCLH_01137 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
CMAJJCLH_01138 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMAJJCLH_01139 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMAJJCLH_01140 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CMAJJCLH_01141 1.6e-55 ctsR K Belongs to the CtsR family
CMAJJCLH_01143 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CMAJJCLH_01144 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CMAJJCLH_01145 6.3e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CMAJJCLH_01146 7.2e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CMAJJCLH_01147 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CMAJJCLH_01158 1.5e-08 S CAAX protease self-immunity
CMAJJCLH_01172 4.2e-31 E IrrE N-terminal-like domain
CMAJJCLH_01174 3.1e-143 L transposase, IS605 OrfB family
CMAJJCLH_01175 1.1e-47 L Initiator Replication protein
CMAJJCLH_01182 1.2e-22
CMAJJCLH_01183 3.8e-93 yihY S Belongs to the UPF0761 family
CMAJJCLH_01184 4.7e-12 mltD CBM50 M Lysin motif
CMAJJCLH_01185 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CMAJJCLH_01186 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
CMAJJCLH_01187 5.1e-54 fld C Flavodoxin
CMAJJCLH_01188 5.1e-53 gtcA S Teichoic acid glycosylation protein
CMAJJCLH_01189 0.0 S Bacterial membrane protein YfhO
CMAJJCLH_01190 1.2e-78 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
CMAJJCLH_01191 1.2e-21 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
CMAJJCLH_01192 1.8e-183 L Probable transposase
CMAJJCLH_01193 3e-38 S Sulfite exporter TauE/SafE
CMAJJCLH_01194 1.8e-70 K Sugar-specific transcriptional regulator TrmB
CMAJJCLH_01195 4.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CMAJJCLH_01196 2.3e-181 pepS E Thermophilic metalloprotease (M29)
CMAJJCLH_01197 3.8e-08 E Amino acid permease
CMAJJCLH_01198 1.5e-243 E Amino acid permease
CMAJJCLH_01199 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
CMAJJCLH_01200 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
CMAJJCLH_01201 5.9e-79 galM 5.1.3.3 G Aldose 1-epimerase
CMAJJCLH_01202 4.3e-213 malT G Transporter, major facilitator family protein
CMAJJCLH_01203 9.4e-101 malR K Transcriptional regulator, LacI family
CMAJJCLH_01204 5.3e-90 kup P Transport of potassium into the cell
CMAJJCLH_01206 2.2e-90 rfbP M Bacterial sugar transferase
CMAJJCLH_01207 2.4e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CMAJJCLH_01208 2.7e-111 ywqE 3.1.3.48 GM PHP domain protein
CMAJJCLH_01209 9.3e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
CMAJJCLH_01210 6.2e-71 epsB M biosynthesis protein
CMAJJCLH_01211 1.2e-23 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
CMAJJCLH_01212 3.3e-101
CMAJJCLH_01213 4.4e-89 2.4.1.342 GT4 M Glycosyl transferases group 1
CMAJJCLH_01214 3.2e-94 M Glycosyl transferases group 1
CMAJJCLH_01216 5.1e-65 wcmJ M Glycosyltransferase sugar-binding region containing DXD motif
CMAJJCLH_01217 9.7e-80 M Glycosyltransferase, group 2 family protein
CMAJJCLH_01218 6.5e-116 cps2J S Polysaccharide biosynthesis protein
CMAJJCLH_01219 2.7e-27 epsH S Hexapeptide repeat of succinyl-transferase
CMAJJCLH_01220 1.6e-106 M PFAM Glycosyl transferase, group 1
CMAJJCLH_01224 5.8e-80 S response to antibiotic
CMAJJCLH_01225 2.3e-15 S zinc-ribbon domain
CMAJJCLH_01226 1.8e-116 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
CMAJJCLH_01227 2.2e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CMAJJCLH_01228 7.3e-132 coaA 2.7.1.33 F Pantothenic acid kinase
CMAJJCLH_01229 1.9e-43 E GDSL-like Lipase/Acylhydrolase
CMAJJCLH_01230 1.4e-45 yqhL P Rhodanese-like protein
CMAJJCLH_01231 4.7e-158 glk 2.7.1.2 G Glucokinase
CMAJJCLH_01232 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
CMAJJCLH_01233 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
CMAJJCLH_01234 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CMAJJCLH_01235 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CMAJJCLH_01236 1.8e-19 D nuclear chromosome segregation
CMAJJCLH_01237 2.9e-76 yciQ P membrane protein (DUF2207)
CMAJJCLH_01238 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
CMAJJCLH_01239 2.8e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
CMAJJCLH_01240 2.9e-26 yneF S UPF0154 protein
CMAJJCLH_01241 2.2e-30 ynzC S UPF0291 protein
CMAJJCLH_01242 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMAJJCLH_01243 9.3e-178 recN L May be involved in recombinational repair of damaged DNA
CMAJJCLH_01244 1.1e-48 argR K Regulates arginine biosynthesis genes
CMAJJCLH_01245 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CMAJJCLH_01246 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CMAJJCLH_01247 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMAJJCLH_01248 6.8e-147 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMAJJCLH_01249 1e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMAJJCLH_01250 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMAJJCLH_01251 3.7e-46 yqhY S Asp23 family, cell envelope-related function
CMAJJCLH_01252 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMAJJCLH_01253 1.3e-41 dut S dUTPase
CMAJJCLH_01254 5.5e-117
CMAJJCLH_01255 7.3e-105
CMAJJCLH_01256 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
CMAJJCLH_01257 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CMAJJCLH_01258 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMAJJCLH_01259 3.1e-95 yeaN P Major Facilitator Superfamily
CMAJJCLH_01260 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CMAJJCLH_01261 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CMAJJCLH_01262 1.7e-66 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
CMAJJCLH_01263 3.5e-86 K response regulator
CMAJJCLH_01264 1e-84 phoR 2.7.13.3 T Histidine kinase
CMAJJCLH_01265 4.1e-08 KT PspC domain protein
CMAJJCLH_01266 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
CMAJJCLH_01267 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CMAJJCLH_01268 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMAJJCLH_01269 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CMAJJCLH_01270 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CMAJJCLH_01271 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CMAJJCLH_01272 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CMAJJCLH_01273 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
CMAJJCLH_01274 7.5e-126 rapZ S Displays ATPase and GTPase activities
CMAJJCLH_01275 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CMAJJCLH_01276 1.8e-149 whiA K May be required for sporulation
CMAJJCLH_01277 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CMAJJCLH_01279 2.5e-181 kup P Transport of potassium into the cell
CMAJJCLH_01281 2e-20 S Domain of unknown function (DUF3284)
CMAJJCLH_01282 2e-159 yfmL L DEAD DEAH box helicase
CMAJJCLH_01283 7e-128 mocA S Oxidoreductase
CMAJJCLH_01284 3.4e-24 S Domain of unknown function (DUF4828)
CMAJJCLH_01285 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
CMAJJCLH_01286 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CMAJJCLH_01287 9.4e-195 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
CMAJJCLH_01288 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
CMAJJCLH_01289 2.6e-163 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CMAJJCLH_01290 2.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CMAJJCLH_01291 9.4e-221 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
CMAJJCLH_01292 1.1e-41 O ADP-ribosylglycohydrolase
CMAJJCLH_01293 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
CMAJJCLH_01294 7.6e-210 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
CMAJJCLH_01295 2.8e-34 K GNAT family
CMAJJCLH_01296 1.7e-40
CMAJJCLH_01298 1e-102 L Transposase
CMAJJCLH_01299 7.8e-62 L Transposase, IS116 IS110 IS902 family
CMAJJCLH_01300 3.3e-98 tnp2 L Transposase
CMAJJCLH_01301 3.1e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
CMAJJCLH_01303 8e-64 srtA 3.4.22.70 M sortase family
CMAJJCLH_01304 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CMAJJCLH_01305 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CMAJJCLH_01306 9.6e-35
CMAJJCLH_01307 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMAJJCLH_01308 4.4e-156 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CMAJJCLH_01309 3.3e-96 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CMAJJCLH_01310 2.4e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
CMAJJCLH_01311 1.1e-39 ybjQ S Belongs to the UPF0145 family
CMAJJCLH_01312 8.2e-07
CMAJJCLH_01313 3e-95 V ABC transporter, ATP-binding protein
CMAJJCLH_01314 1.1e-41 gntR1 K Transcriptional regulator, GntR family
CMAJJCLH_01315 1.9e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
CMAJJCLH_01316 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMAJJCLH_01317 3.8e-262 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
CMAJJCLH_01318 1.7e-107 terC P Integral membrane protein TerC family
CMAJJCLH_01319 1.6e-38 K Transcriptional regulator
CMAJJCLH_01320 9.8e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
CMAJJCLH_01321 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMAJJCLH_01322 4.5e-102 tcyB E ABC transporter
CMAJJCLH_01324 3.7e-13 ponA V the current gene model (or a revised gene model) may contain a frame shift
CMAJJCLH_01325 1e-187 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CMAJJCLH_01326 7.8e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CMAJJCLH_01327 2e-209 mtlR K Mga helix-turn-helix domain
CMAJJCLH_01328 4.9e-176 yjcE P Sodium proton antiporter
CMAJJCLH_01329 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CMAJJCLH_01330 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
CMAJJCLH_01331 5.6e-69 dhaL 2.7.1.121 S Dak2
CMAJJCLH_01332 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
CMAJJCLH_01333 7.9e-113 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
CMAJJCLH_01334 1.7e-61 K Bacterial regulatory proteins, tetR family
CMAJJCLH_01335 8.5e-209 brnQ U Component of the transport system for branched-chain amino acids
CMAJJCLH_01337 1.7e-111 endA F DNA RNA non-specific endonuclease
CMAJJCLH_01338 1.1e-75 XK27_02070 S Nitroreductase family
CMAJJCLH_01339 4.5e-192 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
CMAJJCLH_01340 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
CMAJJCLH_01341 8e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
CMAJJCLH_01342 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CMAJJCLH_01343 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
CMAJJCLH_01344 5.1e-77 azlC E branched-chain amino acid
CMAJJCLH_01345 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
CMAJJCLH_01346 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
CMAJJCLH_01347 1.6e-55 jag S R3H domain protein
CMAJJCLH_01348 9.1e-54 K Transcriptional regulator C-terminal region
CMAJJCLH_01349 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
CMAJJCLH_01350 3.7e-287 pepO 3.4.24.71 O Peptidase family M13
CMAJJCLH_01351 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
CMAJJCLH_01352 2.1e-07 S SdpI/YhfL protein family
CMAJJCLH_01353 7.8e-72 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
CMAJJCLH_01354 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
CMAJJCLH_01355 5.7e-41 wecD K Acetyltransferase GNAT Family
CMAJJCLH_01357 5e-255 XK27_06780 V ABC transporter permease
CMAJJCLH_01358 1.1e-95 XK27_06785 V ABC transporter, ATP-binding protein
CMAJJCLH_01360 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
CMAJJCLH_01361 3.8e-66 ybbL S ABC transporter
CMAJJCLH_01362 6.2e-163 oxlT P Major Facilitator Superfamily
CMAJJCLH_01363 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CMAJJCLH_01364 4.1e-47 S Short repeat of unknown function (DUF308)
CMAJJCLH_01365 1.8e-30 tetR K Transcriptional regulator C-terminal region
CMAJJCLH_01366 1.3e-150 yfeX P Peroxidase
CMAJJCLH_01367 1.5e-16 S Protein of unknown function (DUF3021)
CMAJJCLH_01368 2.6e-39 K LytTr DNA-binding domain
CMAJJCLH_01369 1.2e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
CMAJJCLH_01370 2.9e-209 mmuP E amino acid
CMAJJCLH_01371 5.9e-15 psiE S Phosphate-starvation-inducible E
CMAJJCLH_01372 9.7e-156 oppF P Belongs to the ABC transporter superfamily
CMAJJCLH_01373 1.3e-180 oppD P Belongs to the ABC transporter superfamily
CMAJJCLH_01374 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMAJJCLH_01375 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMAJJCLH_01376 3.1e-202 oppA E ABC transporter, substratebinding protein
CMAJJCLH_01377 4.5e-218 yifK E Amino acid permease
CMAJJCLH_01378 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMAJJCLH_01379 1.8e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
CMAJJCLH_01380 6.5e-66 pgm3 G phosphoglycerate mutase family
CMAJJCLH_01381 1e-252 ctpA 3.6.3.54 P P-type ATPase
CMAJJCLH_01382 1.9e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CMAJJCLH_01383 6.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CMAJJCLH_01384 1.6e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CMAJJCLH_01385 5.4e-181 EG GntP family permease
CMAJJCLH_01386 6.5e-116 KT Putative sugar diacid recognition
CMAJJCLH_01387 1.8e-22 K transcriptional regulator
CMAJJCLH_01388 5.1e-33 hchA S intracellular protease amidase
CMAJJCLH_01389 1.1e-25 hchA S intracellular protease amidase
CMAJJCLH_01390 7.6e-133 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
CMAJJCLH_01391 1.5e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
CMAJJCLH_01392 2.5e-140 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CMAJJCLH_01393 1.8e-171 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
CMAJJCLH_01394 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
CMAJJCLH_01395 1.6e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
CMAJJCLH_01396 1.2e-72 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
CMAJJCLH_01397 4.9e-130 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
CMAJJCLH_01399 8.5e-147 V RRXRR protein
CMAJJCLH_01400 4.9e-194 tnpB L Putative transposase DNA-binding domain
CMAJJCLH_01403 2.1e-64 NU StbA protein
CMAJJCLH_01406 3.4e-15
CMAJJCLH_01407 1.2e-102 res L helicase
CMAJJCLH_01408 1.5e-15
CMAJJCLH_01409 4.9e-38 srtA 3.4.22.70 M Sortase family
CMAJJCLH_01413 5.9e-47 clpC O ATPase family associated with various cellular activities (AAA)
CMAJJCLH_01420 9.3e-07 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CMAJJCLH_01421 8.6e-45 S HicB_like antitoxin of bacterial toxin-antitoxin system
CMAJJCLH_01422 5.1e-152 L transposase, IS605 OrfB family
CMAJJCLH_01423 2e-23 S HicA toxin of bacterial toxin-antitoxin,
CMAJJCLH_01426 1.1e-48 apaH 3.1.3.16 T Calcineurin-like phosphoesterase
CMAJJCLH_01429 1.9e-55 S Fic/DOC family
CMAJJCLH_01430 1e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CMAJJCLH_01431 4.6e-07 S RelB antitoxin
CMAJJCLH_01433 2.3e-16 ps301 K PFAM helix-turn-helix domain protein
CMAJJCLH_01435 1.4e-41 gepA S Protein of unknown function (DUF4065)
CMAJJCLH_01436 3.7e-11 lprD V PFAM secretion protein HlyD family protein
CMAJJCLH_01439 6e-70 XK27_00515 D Glucan-binding protein C
CMAJJCLH_01440 3.1e-30 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CMAJJCLH_01441 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
CMAJJCLH_01442 1.2e-88 nanK GK ROK family
CMAJJCLH_01443 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
CMAJJCLH_01444 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CMAJJCLH_01445 5.6e-75 K Helix-turn-helix domain, rpiR family
CMAJJCLH_01446 5.7e-56 yphA GM NAD dependent epimerase/dehydratase family
CMAJJCLH_01447 2e-216 yjeM E Amino Acid
CMAJJCLH_01449 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMAJJCLH_01450 2.4e-166 tetP J elongation factor G
CMAJJCLH_01451 2e-44 tetP J elongation factor G
CMAJJCLH_01452 1.8e-276 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CMAJJCLH_01453 4.7e-35 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CMAJJCLH_01454 2.2e-41 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CMAJJCLH_01455 1.1e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
CMAJJCLH_01456 9.5e-120 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
CMAJJCLH_01457 1.4e-181 gatC G PTS system sugar-specific permease component
CMAJJCLH_01458 9.2e-36 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
CMAJJCLH_01459 2.7e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMAJJCLH_01460 2.2e-60 K DeoR C terminal sensor domain
CMAJJCLH_01461 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
CMAJJCLH_01462 9.9e-41 trxA O Belongs to the thioredoxin family
CMAJJCLH_01463 3.3e-311 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CMAJJCLH_01464 1.4e-16 cvpA S Colicin V production protein
CMAJJCLH_01465 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CMAJJCLH_01466 1.9e-33 yrzB S Belongs to the UPF0473 family
CMAJJCLH_01467 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMAJJCLH_01468 2.1e-36 yrzL S Belongs to the UPF0297 family
CMAJJCLH_01469 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CMAJJCLH_01470 1e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CMAJJCLH_01471 9.4e-122 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
CMAJJCLH_01472 7.5e-13
CMAJJCLH_01473 2.7e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMAJJCLH_01474 2.5e-66 yrjD S LUD domain
CMAJJCLH_01475 1.6e-245 lutB C 4Fe-4S dicluster domain
CMAJJCLH_01476 6.9e-117 lutA C Cysteine-rich domain
CMAJJCLH_01477 2e-208 yfnA E Amino Acid
CMAJJCLH_01479 4.3e-61 uspA T universal stress protein
CMAJJCLH_01481 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CMAJJCLH_01482 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CMAJJCLH_01483 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
CMAJJCLH_01484 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMAJJCLH_01485 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMAJJCLH_01486 7.1e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CMAJJCLH_01487 9e-20 yaaA S S4 domain protein YaaA
CMAJJCLH_01488 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CMAJJCLH_01489 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CMAJJCLH_01490 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
CMAJJCLH_01491 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CMAJJCLH_01492 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMAJJCLH_01493 1.1e-199 nupG F Nucleoside
CMAJJCLH_01494 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
CMAJJCLH_01495 1.7e-53 K LysR substrate binding domain
CMAJJCLH_01496 1.8e-07
CMAJJCLH_01497 6e-66 yxkH G Polysaccharide deacetylase
CMAJJCLH_01498 9e-30 yqkB S Belongs to the HesB IscA family
CMAJJCLH_01499 1.5e-83 3.1.21.3 V PFAM restriction modification system DNA specificity domain
CMAJJCLH_01500 6.3e-223 hsdM 2.1.1.72 V type I restriction-modification system
CMAJJCLH_01501 7.2e-283 hsdR 3.1.21.3 L DEAD/DEAH box helicase
CMAJJCLH_01502 5.8e-07
CMAJJCLH_01503 1.1e-45 yjaB_1 K Acetyltransferase (GNAT) domain
CMAJJCLH_01504 8.3e-82 yitS S EDD domain protein, DegV family
CMAJJCLH_01505 4.7e-56 racA K Domain of unknown function (DUF1836)
CMAJJCLH_01506 1.8e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CMAJJCLH_01507 2.7e-84 potE2 E amino acid
CMAJJCLH_01509 2e-24
CMAJJCLH_01510 5.6e-146 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
CMAJJCLH_01511 4.9e-69
CMAJJCLH_01512 3.3e-34 S Protein of unknown function (DUF4238)
CMAJJCLH_01513 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CMAJJCLH_01514 3.5e-57 yceD S Uncharacterized ACR, COG1399
CMAJJCLH_01515 1.3e-122 ylbM S Belongs to the UPF0348 family
CMAJJCLH_01516 5.5e-82 H Nodulation protein S (NodS)
CMAJJCLH_01517 5.1e-49 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CMAJJCLH_01518 4.7e-71 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
CMAJJCLH_01519 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CMAJJCLH_01520 1e-29 yhbY J RNA-binding protein
CMAJJCLH_01521 3e-180 yqeH S Ribosome biogenesis GTPase YqeH
CMAJJCLH_01522 2.5e-71 yqeG S HAD phosphatase, family IIIA
CMAJJCLH_01523 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CMAJJCLH_01524 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CMAJJCLH_01525 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CMAJJCLH_01526 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMAJJCLH_01527 9.7e-108 dnaI L Primosomal protein DnaI
CMAJJCLH_01528 2.8e-79 dnaB L replication initiation and membrane attachment
CMAJJCLH_01529 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMAJJCLH_01530 7.8e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CMAJJCLH_01531 1.9e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CMAJJCLH_01532 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMAJJCLH_01533 1.6e-159 mgtE P Acts as a magnesium transporter
CMAJJCLH_01534 8.4e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
CMAJJCLH_01535 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMAJJCLH_01536 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
CMAJJCLH_01537 8.1e-256 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
CMAJJCLH_01538 3.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
CMAJJCLH_01539 1.7e-193 pbuX F xanthine permease
CMAJJCLH_01540 3.3e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CMAJJCLH_01541 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
CMAJJCLH_01542 3.2e-64 S ECF transporter, substrate-specific component
CMAJJCLH_01543 3.9e-128 mleP S Sodium Bile acid symporter family
CMAJJCLH_01544 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
CMAJJCLH_01545 6.2e-72 mleR K LysR family
CMAJJCLH_01546 1.1e-56 K transcriptional
CMAJJCLH_01547 7.6e-41 K Bacterial regulatory proteins, tetR family
CMAJJCLH_01548 6.1e-60 T Belongs to the universal stress protein A family
CMAJJCLH_01549 1.2e-44 K Copper transport repressor CopY TcrY
CMAJJCLH_01550 2.4e-31 3.2.1.18 GH33 M Rib/alpha-like repeat
CMAJJCLH_01552 1.8e-12
CMAJJCLH_01553 7.9e-22 S PIN domain
CMAJJCLH_01554 5.3e-12 D Antitoxin component of a toxin-antitoxin (TA) module
CMAJJCLH_01555 1.2e-88 mesE M Transport protein ComB
CMAJJCLH_01556 1.1e-273 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CMAJJCLH_01559 2.5e-56 K LytTr DNA-binding domain
CMAJJCLH_01560 1.2e-58 2.7.13.3 T GHKL domain
CMAJJCLH_01564 3.1e-16
CMAJJCLH_01566 9.4e-08
CMAJJCLH_01567 6.6e-19
CMAJJCLH_01568 5.9e-39 blpT
CMAJJCLH_01569 3e-87 S Haloacid dehalogenase-like hydrolase
CMAJJCLH_01570 4.6e-15
CMAJJCLH_01572 8.2e-07 fhaB M Rib/alpha-like repeat
CMAJJCLH_01573 1.3e-148 3.2.1.18 GH33 M Rib/alpha-like repeat
CMAJJCLH_01574 2.2e-96 ypuA S Protein of unknown function (DUF1002)
CMAJJCLH_01575 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
CMAJJCLH_01576 7.9e-163 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMAJJCLH_01577 3.2e-37 yncA 2.3.1.79 S Maltose acetyltransferase
CMAJJCLH_01578 1.5e-205 yflS P Sodium:sulfate symporter transmembrane region
CMAJJCLH_01579 2.7e-199 frdC 1.3.5.4 C FAD binding domain
CMAJJCLH_01580 1.1e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CMAJJCLH_01581 5.7e-14 ybaN S Protein of unknown function (DUF454)
CMAJJCLH_01582 3.1e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
CMAJJCLH_01583 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
CMAJJCLH_01584 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
CMAJJCLH_01585 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CMAJJCLH_01586 2.3e-219 cydD CO ABC transporter transmembrane region
CMAJJCLH_01587 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CMAJJCLH_01588 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
CMAJJCLH_01589 2.1e-194 cydA 1.10.3.14 C ubiquinol oxidase
CMAJJCLH_01590 3.1e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
CMAJJCLH_01591 3.7e-28 xlyB 3.5.1.28 CBM50 M LysM domain
CMAJJCLH_01592 2.3e-19 glpE P Rhodanese Homology Domain
CMAJJCLH_01593 2.1e-48 lytE M LysM domain protein
CMAJJCLH_01594 6.9e-92 T Calcineurin-like phosphoesterase superfamily domain
CMAJJCLH_01595 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
CMAJJCLH_01597 8.2e-73 draG O ADP-ribosylglycohydrolase
CMAJJCLH_01598 5.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMAJJCLH_01599 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CMAJJCLH_01600 5.1e-62 divIVA D DivIVA domain protein
CMAJJCLH_01601 3.5e-82 ylmH S S4 domain protein
CMAJJCLH_01602 3e-19 yggT S YGGT family
CMAJJCLH_01603 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CMAJJCLH_01604 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMAJJCLH_01605 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CMAJJCLH_01606 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CMAJJCLH_01607 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMAJJCLH_01608 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMAJJCLH_01609 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMAJJCLH_01610 8.4e-280 ftsI 3.4.16.4 M Penicillin-binding Protein
CMAJJCLH_01611 2.5e-11 ftsL D cell division protein FtsL
CMAJJCLH_01612 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CMAJJCLH_01613 5.2e-64 mraZ K Belongs to the MraZ family
CMAJJCLH_01615 1.6e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
CMAJJCLH_01616 3.1e-98 D Alpha beta
CMAJJCLH_01617 1.8e-108 aatB ET ABC transporter substrate-binding protein
CMAJJCLH_01618 1.4e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CMAJJCLH_01619 1.9e-94 glnP P ABC transporter permease
CMAJJCLH_01620 1.8e-126 minD D Belongs to the ParA family
CMAJJCLH_01621 1.4e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CMAJJCLH_01622 3.4e-54 mreD M rod shape-determining protein MreD
CMAJJCLH_01623 2.1e-88 mreC M Involved in formation and maintenance of cell shape
CMAJJCLH_01624 1.8e-155 mreB D cell shape determining protein MreB
CMAJJCLH_01625 4.5e-21 K Cold shock
CMAJJCLH_01626 6.2e-80 radC L DNA repair protein
CMAJJCLH_01627 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CMAJJCLH_01628 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CMAJJCLH_01629 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CMAJJCLH_01630 9.9e-163 iscS2 2.8.1.7 E Aminotransferase class V
CMAJJCLH_01631 1.2e-172 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CMAJJCLH_01632 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
CMAJJCLH_01633 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CMAJJCLH_01634 5.9e-24 yueI S Protein of unknown function (DUF1694)
CMAJJCLH_01635 3.4e-188 rarA L recombination factor protein RarA
CMAJJCLH_01637 3.2e-73 usp6 T universal stress protein
CMAJJCLH_01638 8.1e-54 tag 3.2.2.20 L glycosylase
CMAJJCLH_01639 2.2e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CMAJJCLH_01640 5.9e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CMAJJCLH_01642 6.8e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
CMAJJCLH_01643 8.4e-298 S membrane
CMAJJCLH_01644 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CMAJJCLH_01645 5.2e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
CMAJJCLH_01646 5.8e-101 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
CMAJJCLH_01647 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CMAJJCLH_01649 1.4e-16
CMAJJCLH_01650 1.8e-198 oatA I Acyltransferase
CMAJJCLH_01651 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CMAJJCLH_01652 2.1e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CMAJJCLH_01653 5.8e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMAJJCLH_01656 1.8e-36 S Phosphoesterase
CMAJJCLH_01657 1.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CMAJJCLH_01658 1.1e-60 yslB S Protein of unknown function (DUF2507)
CMAJJCLH_01666 6.9e-18 D nuclear chromosome segregation
CMAJJCLH_01668 1e-63 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
CMAJJCLH_01669 1.3e-154 2.1.1.72 V N-6 DNA Methylase
CMAJJCLH_01670 1.4e-30 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
CMAJJCLH_01671 1.5e-07
CMAJJCLH_01672 2.5e-56 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
CMAJJCLH_01676 6.1e-103 V domain protein
CMAJJCLH_01677 4e-16
CMAJJCLH_01679 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMAJJCLH_01680 1.1e-172 malY 4.4.1.8 E Aminotransferase, class I
CMAJJCLH_01681 1.2e-117 K AI-2E family transporter
CMAJJCLH_01682 3.1e-61 EG EamA-like transporter family
CMAJJCLH_01683 3.9e-76 L haloacid dehalogenase-like hydrolase
CMAJJCLH_01684 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CMAJJCLH_01685 1.5e-62 1.5.1.38 S NADPH-dependent FMN reductase
CMAJJCLH_01686 7.3e-94 C Luciferase-like monooxygenase
CMAJJCLH_01687 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMAJJCLH_01688 4.5e-129 mleP2 S Sodium Bile acid symporter family
CMAJJCLH_01689 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMAJJCLH_01691 3.6e-44 ydcK S Belongs to the SprT family
CMAJJCLH_01692 2.8e-251 yhgF K Tex-like protein N-terminal domain protein
CMAJJCLH_01693 1.4e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CMAJJCLH_01694 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMAJJCLH_01695 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CMAJJCLH_01696 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
CMAJJCLH_01697 4.6e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMAJJCLH_01699 1.1e-07
CMAJJCLH_01700 1.6e-197 dtpT U amino acid peptide transporter
CMAJJCLH_01701 3.3e-29 M Glycosyl transferases group 1
CMAJJCLH_01702 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
CMAJJCLH_01703 7.4e-40 K Transcriptional regulator
CMAJJCLH_01704 5.4e-31 S CHY zinc finger
CMAJJCLH_01705 1.5e-85 1.1.1.1 C Zinc-binding dehydrogenase
CMAJJCLH_01707 3.4e-41 S Protein of unknown function (DUF1211)
CMAJJCLH_01708 1.8e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
CMAJJCLH_01710 3.3e-41 wecD M Acetyltransferase (GNAT) family
CMAJJCLH_01711 1.4e-77 cps2D 5.1.3.2 M RmlD substrate binding domain
CMAJJCLH_01712 1.5e-66 H Methyltransferase domain
CMAJJCLH_01714 3.7e-16 K DNA-templated transcription, initiation
CMAJJCLH_01718 4.2e-70 L Transposase
CMAJJCLH_01719 1.6e-79 L transposase and inactivated derivatives, IS30 family
CMAJJCLH_01720 5.3e-35 tra L Transposase and inactivated derivatives, IS30 family
CMAJJCLH_01721 1.1e-16 K Cro/C1-type HTH DNA-binding domain
CMAJJCLH_01724 2.9e-39 ebh D nuclear chromosome segregation
CMAJJCLH_01725 1.3e-135 L Transposase
CMAJJCLH_01726 1.6e-74 L Transposase
CMAJJCLH_01727 1.8e-21 L Transposase
CMAJJCLH_01730 4.8e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CMAJJCLH_01731 4.9e-10 L Resolvase, N terminal domain
CMAJJCLH_01733 1.7e-78 L Resolvase, N terminal domain
CMAJJCLH_01734 1.8e-208 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CMAJJCLH_01735 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMAJJCLH_01738 1.6e-151 V Pfam:Methyltransf_26
CMAJJCLH_01739 3.4e-225 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CMAJJCLH_01740 4.7e-153 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMAJJCLH_01741 2.9e-25 L Transposase domain (DUF772)
CMAJJCLH_01742 1e-33 S Enterocin A Immunity
CMAJJCLH_01743 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
CMAJJCLH_01744 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
CMAJJCLH_01745 6.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
CMAJJCLH_01746 1.6e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMAJJCLH_01747 8.2e-154 yacL S domain protein
CMAJJCLH_01748 4.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMAJJCLH_01749 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMAJJCLH_01750 4.9e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CMAJJCLH_01751 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMAJJCLH_01752 1.8e-32 ywiB S Domain of unknown function (DUF1934)
CMAJJCLH_01753 2.9e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CMAJJCLH_01754 1.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CMAJJCLH_01757 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMAJJCLH_01758 1.5e-188 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CMAJJCLH_01759 1.4e-40 rpmE2 J Ribosomal protein L31
CMAJJCLH_01760 2.2e-61
CMAJJCLH_01761 2.2e-249 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
CMAJJCLH_01762 4.1e-21 S by MetaGeneAnnotator
CMAJJCLH_01763 2.2e-07 M PFAM Cna B domain protein
CMAJJCLH_01764 8.1e-27 3.4.22.70 M Sortase family
CMAJJCLH_01765 1.1e-88 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
CMAJJCLH_01766 6e-25 3.4.22.70 M Sortase family
CMAJJCLH_01772 1.9e-08 2.3.1.19 K Cro/C1-type HTH DNA-binding domain
CMAJJCLH_01777 4.2e-40
CMAJJCLH_01778 5.7e-07 L Integrase core domain
CMAJJCLH_01780 2.1e-12 S Thioredoxin
CMAJJCLH_01782 2.3e-116 K Primase C terminal 1 (PriCT-1)
CMAJJCLH_01783 3.1e-40 K Transcriptional regulator
CMAJJCLH_01784 9.4e-202 FbpA K Fibronectin-binding protein
CMAJJCLH_01785 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
CMAJJCLH_01786 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CMAJJCLH_01787 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CMAJJCLH_01788 2.2e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMAJJCLH_01789 4.6e-287 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMAJJCLH_01790 1.3e-139 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMAJJCLH_01791 1.3e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CMAJJCLH_01792 3.3e-90 stp 3.1.3.16 T phosphatase
CMAJJCLH_01793 7.5e-191 KLT serine threonine protein kinase
CMAJJCLH_01794 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CMAJJCLH_01795 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
CMAJJCLH_01796 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CMAJJCLH_01797 4.5e-53 asp S Asp23 family, cell envelope-related function
CMAJJCLH_01798 1.3e-238 yloV S DAK2 domain fusion protein YloV
CMAJJCLH_01799 4e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMAJJCLH_01800 2.7e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CMAJJCLH_01801 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMAJJCLH_01802 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CMAJJCLH_01803 1.3e-208 smc D Required for chromosome condensation and partitioning
CMAJJCLH_01804 7.2e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CMAJJCLH_01805 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CMAJJCLH_01806 5.5e-203 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMAJJCLH_01807 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CMAJJCLH_01808 3.8e-27 ylqC S Belongs to the UPF0109 family
CMAJJCLH_01809 1.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CMAJJCLH_01810 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CMAJJCLH_01811 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
CMAJJCLH_01812 8.2e-199 yfnA E amino acid
CMAJJCLH_01813 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CMAJJCLH_01814 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
CMAJJCLH_01815 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMAJJCLH_01816 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CMAJJCLH_01817 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMAJJCLH_01818 6.1e-19 S Tetratricopeptide repeat
CMAJJCLH_01819 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMAJJCLH_01820 7.8e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CMAJJCLH_01821 7.8e-198 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMAJJCLH_01822 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CMAJJCLH_01823 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMAJJCLH_01824 5e-23 ykzG S Belongs to the UPF0356 family
CMAJJCLH_01825 9.5e-25
CMAJJCLH_01826 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMAJJCLH_01827 2.6e-30 1.1.1.27 C L-malate dehydrogenase activity
CMAJJCLH_01828 1.2e-24 yktA S Belongs to the UPF0223 family
CMAJJCLH_01829 6.3e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
CMAJJCLH_01830 0.0 typA T GTP-binding protein TypA
CMAJJCLH_01831 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
CMAJJCLH_01832 7e-115 manY G PTS system
CMAJJCLH_01833 3.3e-148 manN G system, mannose fructose sorbose family IID component
CMAJJCLH_01834 3e-101 ftsW D Belongs to the SEDS family
CMAJJCLH_01835 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CMAJJCLH_01836 1.8e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
CMAJJCLH_01837 1e-72 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
CMAJJCLH_01838 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CMAJJCLH_01839 1.8e-131 ylbL T Belongs to the peptidase S16 family
CMAJJCLH_01840 2.9e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CMAJJCLH_01841 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMAJJCLH_01842 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMAJJCLH_01843 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMAJJCLH_01844 5.5e-227 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMAJJCLH_01845 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CMAJJCLH_01846 1.2e-74 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CMAJJCLH_01847 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CMAJJCLH_01848 6e-161 purD 6.3.4.13 F Belongs to the GARS family
CMAJJCLH_01849 3e-89 S Acyltransferase family
CMAJJCLH_01851 2e-10 S Protein of unknown function (DUF805)
CMAJJCLH_01854 1.7e-07 K Helix-turn-helix XRE-family like proteins
CMAJJCLH_01857 6.9e-68 sip L Belongs to the 'phage' integrase family
CMAJJCLH_01858 3e-14 S Acyltransferase family
CMAJJCLH_01860 6e-34 L Helix-turn-helix domain
CMAJJCLH_01861 1.4e-67 spx4 1.20.4.1 P ArsC family
CMAJJCLH_01862 1.8e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMAJJCLH_01863 8.5e-230 baeS 2.7.13.3 T Histidine kinase
CMAJJCLH_01864 5e-117 K response regulator
CMAJJCLH_01865 1.5e-33 3.2.1.23 S Domain of unknown function DUF302
CMAJJCLH_01866 4.8e-16 3.2.1.23 S Domain of unknown function DUF302
CMAJJCLH_01867 2.4e-40 S membrane protein (DUF2078)
CMAJJCLH_01868 0.0 3.6.3.4 P haloacid dehalogenase-like hydrolase
CMAJJCLH_01869 5.8e-79 copY K Penicillinase repressor
CMAJJCLH_01875 1.3e-224 E ABC transporter, substratebinding protein
CMAJJCLH_01876 2.8e-116 sufC O FeS assembly ATPase SufC
CMAJJCLH_01877 2.3e-144 sufD O FeS assembly protein SufD
CMAJJCLH_01878 2.4e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CMAJJCLH_01879 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
CMAJJCLH_01880 4.2e-240 sufB O assembly protein SufB
CMAJJCLH_01881 1.3e-49 K Cro/C1-type HTH DNA-binding domain
CMAJJCLH_01882 3.6e-15 Z012_01675 S X-Pro dipeptidyl-peptidase (S15 family)
CMAJJCLH_01883 6.6e-15 yjaB_1 K Psort location Cytoplasmic, score 8.87
CMAJJCLH_01886 7.9e-27 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CMAJJCLH_01887 6.7e-72 ywlG S Belongs to the UPF0340 family
CMAJJCLH_01888 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CMAJJCLH_01889 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMAJJCLH_01890 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CMAJJCLH_01891 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMAJJCLH_01892 0.0 O Belongs to the peptidase S8 family
CMAJJCLH_01893 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
CMAJJCLH_01894 9e-102 qmcA O prohibitin homologues
CMAJJCLH_01895 1.8e-11 S YjcQ protein
CMAJJCLH_01896 5.4e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
CMAJJCLH_01897 2.2e-83 dps P Ferritin-like domain
CMAJJCLH_01898 3.2e-181 pbuG S permease
CMAJJCLH_01899 6.4e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
CMAJJCLH_01900 9e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CMAJJCLH_01901 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CMAJJCLH_01902 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CMAJJCLH_01903 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMAJJCLH_01904 5.4e-13
CMAJJCLH_01905 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
CMAJJCLH_01906 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
CMAJJCLH_01907 6e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMAJJCLH_01908 1.3e-118 gla U Major intrinsic protein
CMAJJCLH_01909 1.5e-45 ykuL S CBS domain
CMAJJCLH_01910 3e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CMAJJCLH_01911 2.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CMAJJCLH_01912 2.6e-86 ykuT M mechanosensitive ion channel
CMAJJCLH_01913 2.8e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CMAJJCLH_01914 4e-64 C FMN binding
CMAJJCLH_01915 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CMAJJCLH_01916 1.7e-54 rplI J Binds to the 23S rRNA
CMAJJCLH_01917 8.8e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CMAJJCLH_01918 1.4e-06
CMAJJCLH_01924 5.1e-08
CMAJJCLH_01931 1.4e-64 G Xylose isomerase domain protein TIM barrel
CMAJJCLH_01932 6.6e-154 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CMAJJCLH_01933 1.1e-206 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMAJJCLH_01934 1.9e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
CMAJJCLH_01935 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CMAJJCLH_01936 7.7e-41 S Iron-sulfur cluster assembly protein
CMAJJCLH_01937 1.3e-66 S Protein of unknown function (DUF1440)
CMAJJCLH_01938 1e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
CMAJJCLH_01939 3.2e-188 mtnE 2.6.1.83 E Aminotransferase
CMAJJCLH_01940 6.9e-37
CMAJJCLH_01941 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CMAJJCLH_01942 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CMAJJCLH_01943 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CMAJJCLH_01944 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CMAJJCLH_01945 1.7e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMAJJCLH_01947 3.1e-111 K response regulator
CMAJJCLH_01948 1.3e-167 arlS 2.7.13.3 T Histidine kinase
CMAJJCLH_01949 5.7e-39
CMAJJCLH_01951 8.2e-16
CMAJJCLH_01952 1.6e-112 rssA S Phospholipase, patatin family
CMAJJCLH_01953 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMAJJCLH_01954 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
CMAJJCLH_01955 1.5e-45 S VIT family
CMAJJCLH_01956 3.6e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMAJJCLH_01957 5.5e-243 lysP E amino acid
CMAJJCLH_01958 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
CMAJJCLH_01959 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CMAJJCLH_01960 1.2e-13 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CMAJJCLH_01961 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
CMAJJCLH_01962 7.6e-83 lysR5 K LysR substrate binding domain
CMAJJCLH_01963 1.7e-119 yxaA S membrane transporter protein
CMAJJCLH_01964 2.6e-32 ywjH S Protein of unknown function (DUF1634)
CMAJJCLH_01965 7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CMAJJCLH_01966 1.7e-225 pipD E Dipeptidase
CMAJJCLH_01967 1.8e-21 K helix_turn_helix multiple antibiotic resistance protein
CMAJJCLH_01968 5.7e-165 EGP Major facilitator Superfamily
CMAJJCLH_01969 4.7e-81 S L,D-transpeptidase catalytic domain
CMAJJCLH_01970 1.9e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CMAJJCLH_01971 4.3e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CMAJJCLH_01972 7.2e-27 ydiI Q Thioesterase superfamily
CMAJJCLH_01973 5.6e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
CMAJJCLH_01974 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
CMAJJCLH_01975 6.4e-114 degV S EDD domain protein, DegV family
CMAJJCLH_01976 3.4e-226 cadA P P-type ATPase
CMAJJCLH_01977 1.8e-254 E Amino acid permease
CMAJJCLH_01978 2.1e-83 S Membrane
CMAJJCLH_01979 1.6e-49 cps3F
CMAJJCLH_01980 3.3e-283 fruA 2.7.1.202 GT Phosphotransferase System
CMAJJCLH_01981 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CMAJJCLH_01982 9e-88 fruR K DeoR C terminal sensor domain
CMAJJCLH_01983 6.7e-219 XK27_08635 S UPF0210 protein
CMAJJCLH_01984 4.1e-27 gcvR T Belongs to the UPF0237 family
CMAJJCLH_01985 2.3e-38
CMAJJCLH_01986 1.1e-76 E GDSL-like Lipase/Acylhydrolase family
CMAJJCLH_01987 9.2e-56 S Protein of unknown function (DUF975)
CMAJJCLH_01988 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
CMAJJCLH_01989 8.8e-230 lpdA 1.8.1.4 C Dehydrogenase
CMAJJCLH_01990 1.4e-178 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CMAJJCLH_01991 2.8e-166 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
CMAJJCLH_01992 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
CMAJJCLH_01995 2.3e-34 S Protein of unknown function (DUF4256)
CMAJJCLH_01996 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
CMAJJCLH_01997 2.4e-31 metI U ABC transporter permease
CMAJJCLH_01998 2.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMAJJCLH_02000 3.3e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
CMAJJCLH_02001 1.3e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CMAJJCLH_02002 2.3e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
CMAJJCLH_02003 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
CMAJJCLH_02004 3e-84 drgA C nitroreductase
CMAJJCLH_02005 8.8e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
CMAJJCLH_02006 9.6e-68 metI P ABC transporter permease
CMAJJCLH_02007 1.5e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMAJJCLH_02008 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
CMAJJCLH_02009 1e-143 2.1.1.14 E methionine synthase, vitamin-B12 independent
CMAJJCLH_02010 1e-99 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CMAJJCLH_02011 9.5e-82 S Belongs to the UPF0246 family
CMAJJCLH_02012 7.9e-12 S CAAX protease self-immunity
CMAJJCLH_02013 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
CMAJJCLH_02014 5.1e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMAJJCLH_02017 6.8e-73 gshR 1.8.1.7 C Glutathione reductase
CMAJJCLH_02018 4.9e-179 proV E ABC transporter, ATP-binding protein
CMAJJCLH_02019 5.3e-263 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CMAJJCLH_02022 3.5e-98 cadD P Cadmium resistance transporter
CMAJJCLH_02023 5.3e-18
CMAJJCLH_02026 4e-48 L Resolvase, N terminal domain
CMAJJCLH_02027 2.3e-53 S Bacterial protein of unknown function (DUF961)
CMAJJCLH_02028 1e-63 S Bacterial protein of unknown function (DUF961)
CMAJJCLH_02029 0.0 tetP J elongation factor G
CMAJJCLH_02030 1e-30
CMAJJCLH_02031 2.3e-182 cycA E Amino acid permease
CMAJJCLH_02032 6.6e-57 S Calcineurin-like phosphoesterase
CMAJJCLH_02033 1.9e-53 yutD S Protein of unknown function (DUF1027)
CMAJJCLH_02034 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CMAJJCLH_02035 3.5e-32 S Protein of unknown function (DUF1461)
CMAJJCLH_02036 8.8e-92 dedA S SNARE associated Golgi protein
CMAJJCLH_02037 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CMAJJCLH_02038 8.8e-50 yugI 5.3.1.9 J general stress protein
CMAJJCLH_02039 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMAJJCLH_02040 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
CMAJJCLH_02041 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMAJJCLH_02042 1e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
CMAJJCLH_02043 1.1e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
CMAJJCLH_02044 3.1e-30 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CMAJJCLH_02045 5.3e-279 M Phage tail tape measure protein TP901
CMAJJCLH_02046 1.6e-138 S Phage tail protein
CMAJJCLH_02047 5.6e-272 rny D peptidase
CMAJJCLH_02048 5.1e-99 M Prophage endopeptidase tail
CMAJJCLH_02049 0.0 pepN 3.4.11.2 E aminopeptidase
CMAJJCLH_02050 1.1e-35
CMAJJCLH_02052 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
CMAJJCLH_02053 6.6e-63 licT K transcriptional antiterminator
CMAJJCLH_02054 1.4e-28 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CMAJJCLH_02055 9.3e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
CMAJJCLH_02056 1.2e-135 pfoS S Phosphotransferase system, EIIC
CMAJJCLH_02057 1.1e-27 K Helix-turn-helix XRE-family like proteins
CMAJJCLH_02058 1.1e-118 repE K Primase C terminal 1 (PriCT-1)
CMAJJCLH_02062 2.9e-137 cggR K Putative sugar-binding domain
CMAJJCLH_02063 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CMAJJCLH_02064 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CMAJJCLH_02065 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CMAJJCLH_02066 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMAJJCLH_02067 2e-47 pts33BCA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Pts system
CMAJJCLH_02068 6.8e-169 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMAJJCLH_02069 1.6e-36 S Replication initiator protein A (RepA) N-terminus
CMAJJCLH_02070 9.4e-109 L Initiator Replication protein
CMAJJCLH_02072 4.1e-15 ywzB S Protein of unknown function (DUF1146)
CMAJJCLH_02073 7.1e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMAJJCLH_02074 4.1e-165 mbl D Cell shape determining protein MreB Mrl
CMAJJCLH_02075 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
CMAJJCLH_02076 1.3e-13 S Protein of unknown function (DUF2969)
CMAJJCLH_02077 6.1e-187 rodA D Belongs to the SEDS family
CMAJJCLH_02078 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
CMAJJCLH_02079 3.1e-30 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CMAJJCLH_02080 2.6e-259 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CMAJJCLH_02081 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMAJJCLH_02082 1.6e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CMAJJCLH_02083 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMAJJCLH_02084 2.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CMAJJCLH_02085 7.2e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CMAJJCLH_02086 1.1e-40 yabR J RNA binding
CMAJJCLH_02087 2.3e-18 divIC D Septum formation initiator
CMAJJCLH_02088 3.6e-31 yabO J S4 domain protein
CMAJJCLH_02089 7.3e-140 yabM S Polysaccharide biosynthesis protein
CMAJJCLH_02090 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMAJJCLH_02091 3.2e-74 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CMAJJCLH_02092 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CMAJJCLH_02093 5.5e-86 S (CBS) domain
CMAJJCLH_02094 8.1e-142 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CMAJJCLH_02095 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMAJJCLH_02096 7.2e-53 perR P Belongs to the Fur family
CMAJJCLH_02097 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
CMAJJCLH_02098 8e-98 sbcC L Putative exonuclease SbcCD, C subunit
CMAJJCLH_02099 2.3e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CMAJJCLH_02100 7.6e-39 M LysM domain protein
CMAJJCLH_02101 1.5e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
CMAJJCLH_02102 2.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CMAJJCLH_02103 3.9e-34 ygfC K Bacterial regulatory proteins, tetR family
CMAJJCLH_02104 8.2e-111 hrtB V ABC transporter permease
CMAJJCLH_02105 4e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
CMAJJCLH_02107 6.6e-39 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CMAJJCLH_02108 0.0 helD 3.6.4.12 L DNA helicase
CMAJJCLH_02109 8.9e-246 yjbQ P TrkA C-terminal domain protein
CMAJJCLH_02110 3.4e-23
CMAJJCLH_02111 1.2e-59 rpsI J Belongs to the universal ribosomal protein uS9 family
CMAJJCLH_02112 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMAJJCLH_02113 1.2e-124 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CMAJJCLH_02114 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMAJJCLH_02115 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMAJJCLH_02116 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMAJJCLH_02117 4.8e-53 rplQ J Ribosomal protein L17
CMAJJCLH_02118 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMAJJCLH_02119 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CMAJJCLH_02120 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMAJJCLH_02121 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CMAJJCLH_02122 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMAJJCLH_02123 7.6e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CMAJJCLH_02124 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CMAJJCLH_02125 1e-67 rplO J Binds to the 23S rRNA
CMAJJCLH_02126 2.1e-22 rpmD J Ribosomal protein L30
CMAJJCLH_02127 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CMAJJCLH_02128 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMAJJCLH_02129 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CMAJJCLH_02130 7.4e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMAJJCLH_02131 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMAJJCLH_02132 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMAJJCLH_02133 1.6e-46 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMAJJCLH_02134 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CMAJJCLH_02135 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CMAJJCLH_02136 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
CMAJJCLH_02137 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CMAJJCLH_02138 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMAJJCLH_02139 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CMAJJCLH_02140 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMAJJCLH_02141 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMAJJCLH_02142 3.8e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CMAJJCLH_02143 1e-100 rplD J Forms part of the polypeptide exit tunnel
CMAJJCLH_02144 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMAJJCLH_02145 3.7e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
CMAJJCLH_02146 6.8e-165 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CMAJJCLH_02147 2.2e-79 K rpiR family
CMAJJCLH_02148 4.5e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
CMAJJCLH_02149 5.5e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
CMAJJCLH_02150 3.8e-21 K Acetyltransferase (GNAT) domain
CMAJJCLH_02151 2.9e-182 steT E amino acid
CMAJJCLH_02152 1.3e-86 S Fic/DOC family
CMAJJCLH_02156 2.5e-196 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
CMAJJCLH_02157 3.6e-116 S Glycosyl transferase family 2
CMAJJCLH_02158 7.4e-64 D peptidase
CMAJJCLH_02159 0.0 asnB 6.3.5.4 E Asparagine synthase
CMAJJCLH_02160 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CMAJJCLH_02161 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CMAJJCLH_02162 3.3e-165 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CMAJJCLH_02163 2.6e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CMAJJCLH_02165 1.1e-90 infB UW LPXTG-motif cell wall anchor domain protein
CMAJJCLH_02166 1.2e-13 S by MetaGeneAnnotator
CMAJJCLH_02171 5.3e-07 N Bacterial Ig-like domain 2
CMAJJCLH_02172 4.2e-27 S Calcineurin-like phosphoesterase
CMAJJCLH_02174 0.0 clpE O Belongs to the ClpA ClpB family
CMAJJCLH_02175 1.5e-15
CMAJJCLH_02176 9.7e-37 ptsH G phosphocarrier protein HPR
CMAJJCLH_02177 6.9e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMAJJCLH_02178 6.7e-146 lmrP E Major Facilitator Superfamily
CMAJJCLH_02179 1.8e-169 T PhoQ Sensor
CMAJJCLH_02180 5e-104 K response regulator
CMAJJCLH_02181 5e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMAJJCLH_02185 2.6e-16 S RelB antitoxin
CMAJJCLH_02186 4.6e-37
CMAJJCLH_02190 9.9e-62 3.6.4.12 S PD-(D/E)XK nuclease family transposase
CMAJJCLH_02191 8.8e-53 L Protein involved in initiation of plasmid replication
CMAJJCLH_02192 2e-14 vatD S acetyltransferase'
CMAJJCLH_02193 3.6e-16
CMAJJCLH_02194 2.1e-134 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylase
CMAJJCLH_02198 1.4e-45 yphJ 4.1.1.44 S decarboxylase
CMAJJCLH_02199 1.1e-55 yphH S Cupin domain
CMAJJCLH_02200 2.4e-46 C Flavodoxin
CMAJJCLH_02201 3.6e-56 S CAAX protease self-immunity
CMAJJCLH_02202 1.2e-102 pgm3 G phosphoglycerate mutase
CMAJJCLH_02203 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CMAJJCLH_02204 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CMAJJCLH_02205 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMAJJCLH_02206 7.4e-67 M ErfK YbiS YcfS YnhG
CMAJJCLH_02207 1e-107 XK27_08845 S ABC transporter, ATP-binding protein
CMAJJCLH_02208 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
CMAJJCLH_02209 7.8e-132 ABC-SBP S ABC transporter
CMAJJCLH_02210 1.4e-158 potD P ABC transporter
CMAJJCLH_02211 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
CMAJJCLH_02212 9.5e-120 potB P ABC transporter permease
CMAJJCLH_02213 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CMAJJCLH_02214 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CMAJJCLH_02215 1.6e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
CMAJJCLH_02216 1.5e-235 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CMAJJCLH_02217 3.9e-13 S Enterocin A Immunity
CMAJJCLH_02218 2.2e-16 pspC KT PspC domain
CMAJJCLH_02219 2.4e-16 S Putative adhesin
CMAJJCLH_02220 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
CMAJJCLH_02221 8.1e-38 K transcriptional regulator PadR family
CMAJJCLH_02222 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
CMAJJCLH_02223 4.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
CMAJJCLH_02224 2.4e-164 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMAJJCLH_02225 1.1e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CMAJJCLH_02226 3.5e-70 mltD CBM50 M NlpC P60 family protein
CMAJJCLH_02227 1.8e-52 manO S Domain of unknown function (DUF956)
CMAJJCLH_02228 2.1e-147 manN G system, mannose fructose sorbose family IID component
CMAJJCLH_02229 6.4e-116 manY G PTS system sorbose-specific iic component
CMAJJCLH_02230 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
CMAJJCLH_02231 4.1e-80 rbsB G sugar-binding domain protein
CMAJJCLH_02232 5.1e-99 baeS T Histidine kinase
CMAJJCLH_02233 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
CMAJJCLH_02234 1.8e-120 G Bacterial extracellular solute-binding protein
CMAJJCLH_02235 9.1e-71 S Protein of unknown function (DUF554)
CMAJJCLH_02236 1e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMAJJCLH_02237 1.9e-32 merR K MerR HTH family regulatory protein
CMAJJCLH_02238 2.1e-197 lmrB EGP Major facilitator Superfamily
CMAJJCLH_02239 7e-34 S Domain of unknown function (DUF4811)
CMAJJCLH_02240 4.3e-41 S CAAX protease self-immunity
CMAJJCLH_02241 1.3e-60 yceE S haloacid dehalogenase-like hydrolase
CMAJJCLH_02242 7.6e-74 glcR K DeoR C terminal sensor domain
CMAJJCLH_02243 1.7e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CMAJJCLH_02244 1.3e-183 lmrB EGP Major facilitator Superfamily
CMAJJCLH_02245 2.1e-54 bioY S BioY family
CMAJJCLH_02246 1.4e-94 S Predicted membrane protein (DUF2207)
CMAJJCLH_02247 1.4e-19
CMAJJCLH_02248 4.4e-37 M Glycosyltransferase group 2 family protein
CMAJJCLH_02249 7.4e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
CMAJJCLH_02250 2.8e-58 ktrA P TrkA-N domain
CMAJJCLH_02251 1.2e-114 ntpJ P Potassium uptake protein
CMAJJCLH_02252 5.3e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
CMAJJCLH_02253 1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
CMAJJCLH_02254 3.5e-216 scrB 3.2.1.26 GH32 G invertase
CMAJJCLH_02255 1.7e-147 scrR K helix_turn _helix lactose operon repressor
CMAJJCLH_02257 6.2e-210 glnP P ABC transporter
CMAJJCLH_02258 9.3e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CMAJJCLH_02259 1e-43 2.7.13.3 T protein histidine kinase activity
CMAJJCLH_02260 3e-35 agrA KT Response regulator of the LytR AlgR family
CMAJJCLH_02261 2.1e-19 M domain protein
CMAJJCLH_02265 1.2e-09
CMAJJCLH_02266 3.7e-26 radC L DNA repair protein
CMAJJCLH_02273 3.9e-60 hsdM 2.1.1.72 V type I restriction-modification system
CMAJJCLH_02274 2.2e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
CMAJJCLH_02275 5.6e-13 S RloB-like protein
CMAJJCLH_02276 2e-57 S AAA domain, putative AbiEii toxin, Type IV TA system
CMAJJCLH_02277 2.3e-25 L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMAJJCLH_02278 2.1e-21
CMAJJCLH_02279 3.2e-12 N Bacterial Ig-like domain 2
CMAJJCLH_02282 3.3e-15 S HicB family
CMAJJCLH_02283 7.5e-18 hicA S HicA toxin of bacterial toxin-antitoxin,
CMAJJCLH_02287 3.6e-117 O AAA domain (Cdc48 subfamily)
CMAJJCLH_02288 2.3e-65
CMAJJCLH_02291 2.7e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
CMAJJCLH_02292 8.7e-117 M Glycosyl hydrolases family 25
CMAJJCLH_02294 3.9e-246 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CMAJJCLH_02295 1e-32 asp3 S Accessory Sec system protein Asp3
CMAJJCLH_02296 5.8e-105 asp2 3.4.11.5 S Accessory Sec system protein Asp2
CMAJJCLH_02297 9.2e-90 asp1 S Accessory Sec system protein Asp1
CMAJJCLH_02298 6.6e-64 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
CMAJJCLH_02299 3.3e-134 S interspecies interaction between organisms
CMAJJCLH_02300 4.7e-207 G glycerol-3-phosphate transporter
CMAJJCLH_02301 9.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMAJJCLH_02302 9.6e-146 htrA 3.4.21.107 O serine protease
CMAJJCLH_02303 1.7e-116 vicX 3.1.26.11 S domain protein
CMAJJCLH_02304 6.8e-30 yyaQ S YjbR
CMAJJCLH_02305 2.1e-79 yycI S YycH protein
CMAJJCLH_02306 1.3e-102 yycH S YycH protein
CMAJJCLH_02307 1.1e-272 vicK 2.7.13.3 T Histidine kinase
CMAJJCLH_02308 9e-114 K response regulator
CMAJJCLH_02309 1.8e-120 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
CMAJJCLH_02310 3.9e-105 yxeH S hydrolase
CMAJJCLH_02312 4.3e-96 S Domain of unknown function DUF87
CMAJJCLH_02314 1.1e-229 V ABC transporter transmembrane region
CMAJJCLH_02315 2e-215 XK27_09600 V ABC transporter, ATP-binding protein
CMAJJCLH_02316 1.2e-31 K Transcriptional regulator, MarR family
CMAJJCLH_02317 8.3e-172 S Putative peptidoglycan binding domain
CMAJJCLH_02319 4e-23 relB L RelB antitoxin
CMAJJCLH_02320 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CMAJJCLH_02321 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
CMAJJCLH_02322 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CMAJJCLH_02323 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CMAJJCLH_02324 1.8e-222 pepF E Oligopeptidase F
CMAJJCLH_02325 2.2e-96 yicL EG EamA-like transporter family
CMAJJCLH_02326 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
CMAJJCLH_02327 4.4e-170 yjjP S Putative threonine/serine exporter
CMAJJCLH_02328 2.8e-109 glcU U sugar transport
CMAJJCLH_02329 3.8e-14 yobS K transcriptional regulator
CMAJJCLH_02330 3.8e-152 mdtG EGP Major facilitator Superfamily
CMAJJCLH_02331 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CMAJJCLH_02332 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
CMAJJCLH_02333 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMAJJCLH_02334 3.6e-17 yneR
CMAJJCLH_02335 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
CMAJJCLH_02336 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CMAJJCLH_02337 3.3e-12 yiiE S Protein of unknown function (DUF1211)
CMAJJCLH_02338 3.7e-37 yiiE S Protein of unknown function (DUF1211)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)