ORF_ID e_value Gene_name EC_number CAZy COGs Description
GPFHHGKB_00001 1.2e-22
GPFHHGKB_00003 5.2e-12 recD 3.1.11.5 L Helix-hairpin-helix containing domain
GPFHHGKB_00005 2.1e-07
GPFHHGKB_00020 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GPFHHGKB_00021 6.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPFHHGKB_00022 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
GPFHHGKB_00023 1.1e-149 EGP Sugar (and other) transporter
GPFHHGKB_00025 1.8e-38
GPFHHGKB_00026 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GPFHHGKB_00027 1.5e-22 S Family of unknown function (DUF5322)
GPFHHGKB_00028 3.1e-36 rnhA 3.1.26.4 L Ribonuclease HI
GPFHHGKB_00029 6.1e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GPFHHGKB_00030 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GPFHHGKB_00032 9.2e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GPFHHGKB_00033 1.2e-171 patA 2.6.1.1 E Aminotransferase
GPFHHGKB_00034 1.1e-114 glcR K DeoR C terminal sensor domain
GPFHHGKB_00035 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
GPFHHGKB_00036 4.7e-134 K Transcriptional regulator
GPFHHGKB_00037 2e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPFHHGKB_00038 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GPFHHGKB_00039 3.8e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GPFHHGKB_00040 7.4e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GPFHHGKB_00041 3.5e-204 pyrP F Permease
GPFHHGKB_00042 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GPFHHGKB_00043 1.4e-127 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPFHHGKB_00044 3.4e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPFHHGKB_00045 5.1e-57 3.1.3.18 J HAD-hyrolase-like
GPFHHGKB_00046 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GPFHHGKB_00047 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPFHHGKB_00048 4.8e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GPFHHGKB_00049 1.9e-116 prmA J Ribosomal protein L11 methyltransferase
GPFHHGKB_00050 1.7e-42 XK27_03960 S Protein of unknown function (DUF3013)
GPFHHGKB_00051 3.9e-144 iunH2 3.2.2.1 F nucleoside hydrolase
GPFHHGKB_00052 6.4e-12
GPFHHGKB_00053 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPFHHGKB_00054 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
GPFHHGKB_00055 1.8e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPFHHGKB_00056 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPFHHGKB_00057 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPFHHGKB_00058 6.9e-43 yodB K Transcriptional regulator, HxlR family
GPFHHGKB_00059 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPFHHGKB_00060 1e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPFHHGKB_00064 5.9e-132 lys 3.5.1.104 M Glycosyl hydrolases family 25
GPFHHGKB_00065 6.5e-10 hol S Bacteriophage holin
GPFHHGKB_00067 1.2e-13 S by MetaGeneAnnotator
GPFHHGKB_00072 5.3e-07 N Bacterial Ig-like domain 2
GPFHHGKB_00073 3.1e-21
GPFHHGKB_00074 9e-36 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
GPFHHGKB_00075 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GPFHHGKB_00076 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPFHHGKB_00077 5.1e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPFHHGKB_00078 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPFHHGKB_00079 4.1e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPFHHGKB_00080 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPFHHGKB_00081 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPFHHGKB_00082 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
GPFHHGKB_00083 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPFHHGKB_00084 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GPFHHGKB_00085 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GPFHHGKB_00086 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPFHHGKB_00087 6.8e-86 tdk 2.7.1.21 F thymidine kinase
GPFHHGKB_00088 1e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
GPFHHGKB_00089 3.5e-110 cobQ S glutamine amidotransferase
GPFHHGKB_00090 2e-111 ampC V Beta-lactamase
GPFHHGKB_00091 1.5e-31
GPFHHGKB_00092 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPFHHGKB_00093 9.2e-206 glnP P ABC transporter
GPFHHGKB_00095 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GPFHHGKB_00096 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GPFHHGKB_00097 1.5e-274 dnaK O Heat shock 70 kDa protein
GPFHHGKB_00098 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPFHHGKB_00099 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GPFHHGKB_00100 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GPFHHGKB_00101 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPFHHGKB_00102 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPFHHGKB_00103 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPFHHGKB_00104 6.9e-26 ylxQ J ribosomal protein
GPFHHGKB_00105 1.4e-39 ylxR K Protein of unknown function (DUF448)
GPFHHGKB_00106 4.8e-170 nusA K Participates in both transcription termination and antitermination
GPFHHGKB_00107 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
GPFHHGKB_00108 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPFHHGKB_00109 1.7e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GPFHHGKB_00110 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GPFHHGKB_00111 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
GPFHHGKB_00112 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPFHHGKB_00113 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GPFHHGKB_00114 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GPFHHGKB_00115 2.7e-48 S Domain of unknown function (DUF956)
GPFHHGKB_00116 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPFHHGKB_00118 2e-247 glnA 6.3.1.2 E glutamine synthetase
GPFHHGKB_00119 1.3e-45 glnR K Transcriptional regulator
GPFHHGKB_00120 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
GPFHHGKB_00121 5.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPFHHGKB_00122 2.8e-16 WQ51_02665 S Protein of unknown function (DUF3042)
GPFHHGKB_00123 9.2e-104 tatD L hydrolase, TatD family
GPFHHGKB_00124 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPFHHGKB_00125 7e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GPFHHGKB_00126 1.2e-22 veg S Biofilm formation stimulator VEG
GPFHHGKB_00127 8e-90 S Alpha/beta hydrolase of unknown function (DUF915)
GPFHHGKB_00128 1.7e-138 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
GPFHHGKB_00129 2.8e-47 argR K Regulates arginine biosynthesis genes
GPFHHGKB_00130 9e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPFHHGKB_00131 3e-155 amtB P ammonium transporter
GPFHHGKB_00132 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
GPFHHGKB_00133 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GPFHHGKB_00134 2.9e-149 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
GPFHHGKB_00135 2.9e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPFHHGKB_00136 1.2e-103 pfoS S Phosphotransferase system, EIIC
GPFHHGKB_00138 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPFHHGKB_00139 2.5e-44 adhR K helix_turn_helix, mercury resistance
GPFHHGKB_00140 5.2e-137 purR 2.4.2.7 F pur operon repressor
GPFHHGKB_00141 1.5e-47 EGP Transmembrane secretion effector
GPFHHGKB_00142 5.1e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPFHHGKB_00143 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPFHHGKB_00144 1.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPFHHGKB_00146 5.8e-112 dkg S reductase
GPFHHGKB_00147 1.3e-24
GPFHHGKB_00148 4.6e-61 L Resolvase, N-terminal domain
GPFHHGKB_00149 5.3e-99 L Probable transposase
GPFHHGKB_00150 1e-78 2.4.2.3 F Phosphorylase superfamily
GPFHHGKB_00151 1.4e-290 ybiT S ABC transporter, ATP-binding protein
GPFHHGKB_00152 1.5e-62 bCE_4747 S Beta-lactamase superfamily domain
GPFHHGKB_00153 3.5e-100 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GPFHHGKB_00154 3e-124 S overlaps another CDS with the same product name
GPFHHGKB_00155 2.9e-86 S overlaps another CDS with the same product name
GPFHHGKB_00157 1.4e-56 spoVK O ATPase family associated with various cellular activities (AAA)
GPFHHGKB_00158 6.9e-23
GPFHHGKB_00159 4.1e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
GPFHHGKB_00161 3.1e-73
GPFHHGKB_00162 2.8e-22
GPFHHGKB_00163 4.2e-103 ydcZ S Putative inner membrane exporter, YdcZ
GPFHHGKB_00164 5.8e-88 S hydrolase
GPFHHGKB_00165 3.3e-205 ywfO S HD domain protein
GPFHHGKB_00166 1.3e-85 yfeJ 6.3.5.2 F glutamine amidotransferase
GPFHHGKB_00167 9.5e-58 tlpA2 L Transposase IS200 like
GPFHHGKB_00168 6e-70 XK27_00515 D Glucan-binding protein C
GPFHHGKB_00171 3.7e-11 lprD V PFAM secretion protein HlyD family protein
GPFHHGKB_00172 1.4e-41 gepA S Protein of unknown function (DUF4065)
GPFHHGKB_00174 2.3e-16 ps301 K PFAM helix-turn-helix domain protein
GPFHHGKB_00176 4.6e-07 S RelB antitoxin
GPFHHGKB_00177 1e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GPFHHGKB_00178 1.9e-55 S Fic/DOC family
GPFHHGKB_00181 1.1e-48 apaH 3.1.3.16 T Calcineurin-like phosphoesterase
GPFHHGKB_00184 2e-23 S HicA toxin of bacterial toxin-antitoxin,
GPFHHGKB_00185 5.1e-152 L transposase, IS605 OrfB family
GPFHHGKB_00186 8.6e-45 S HicB_like antitoxin of bacterial toxin-antitoxin system
GPFHHGKB_00187 9.3e-07 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GPFHHGKB_00198 1.1e-47 L Initiator Replication protein
GPFHHGKB_00199 3.1e-143 L transposase, IS605 OrfB family
GPFHHGKB_00201 4.2e-31 E IrrE N-terminal-like domain
GPFHHGKB_00215 1.5e-08 S CAAX protease self-immunity
GPFHHGKB_00217 2e-32 dprA LU DNA protecting protein DprA
GPFHHGKB_00218 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPFHHGKB_00219 2.8e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPFHHGKB_00220 3.6e-24 yozE S Belongs to the UPF0346 family
GPFHHGKB_00221 8.8e-54 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
GPFHHGKB_00222 4.5e-81 ypmR E GDSL-like Lipase/Acylhydrolase
GPFHHGKB_00224 3.5e-113 S Aldo keto reductase
GPFHHGKB_00225 1.1e-35 K helix_turn_helix, mercury resistance
GPFHHGKB_00226 8.7e-135 yvgN C Aldo keto reductase
GPFHHGKB_00227 3.2e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPFHHGKB_00228 1.3e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPFHHGKB_00229 4.2e-275 yfmR S ABC transporter, ATP-binding protein
GPFHHGKB_00230 3.9e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GPFHHGKB_00231 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GPFHHGKB_00232 7.9e-107 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPFHHGKB_00233 3e-68 xerD L Phage integrase, N-terminal SAM-like domain
GPFHHGKB_00235 1.4e-56 yqeY S YqeY-like protein
GPFHHGKB_00236 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GPFHHGKB_00237 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GPFHHGKB_00240 4.9e-99 epsJ1 M Glycosyltransferase like family 2
GPFHHGKB_00241 3.7e-84 M Glycosyltransferase sugar-binding region containing DXD motif
GPFHHGKB_00242 3.6e-92 M transferase activity, transferring glycosyl groups
GPFHHGKB_00243 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPFHHGKB_00244 2.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPFHHGKB_00245 1.5e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPFHHGKB_00246 5.1e-56 dnaD L DnaD domain protein
GPFHHGKB_00247 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
GPFHHGKB_00248 3.1e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
GPFHHGKB_00249 3.1e-36 ypmB S Protein conserved in bacteria
GPFHHGKB_00250 3.4e-225 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GPFHHGKB_00251 9.5e-95 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
GPFHHGKB_00252 1.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GPFHHGKB_00253 6.7e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GPFHHGKB_00254 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GPFHHGKB_00255 8.4e-105 holA 2.7.7.7 L DNA polymerase III delta subunit
GPFHHGKB_00256 4.7e-156 comEC S Competence protein ComEC
GPFHHGKB_00257 2e-69 comEB 3.5.4.12 F ComE operon protein 2
GPFHHGKB_00258 3.1e-50 comEA L Competence protein ComEA
GPFHHGKB_00259 3.4e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
GPFHHGKB_00260 4e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GPFHHGKB_00261 2.2e-20
GPFHHGKB_00263 2.3e-122 K LysR substrate binding domain
GPFHHGKB_00264 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPFHHGKB_00267 8.5e-147 V RRXRR protein
GPFHHGKB_00269 8.5e-19 S protein disulfide oxidoreductase activity
GPFHHGKB_00277 5.8e-31
GPFHHGKB_00279 1.1e-50 Q DNA (cytosine-5-)-methyltransferase activity
GPFHHGKB_00285 2.3e-99 O ATPase family associated with various cellular activities (AAA)
GPFHHGKB_00288 1.1e-132 L transposase, IS605 OrfB family
GPFHHGKB_00296 3.9e-40
GPFHHGKB_00299 5.1e-60 3.1.3.16, 3.1.4.37 T AAA domain
GPFHHGKB_00304 1.9e-32 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPFHHGKB_00313 9.9e-49 M Prophage endopeptidase tail
GPFHHGKB_00319 8.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
GPFHHGKB_00320 2e-17
GPFHHGKB_00321 1.9e-104 azlC E AzlC protein
GPFHHGKB_00322 1.3e-38 azlD S branched-chain amino acid
GPFHHGKB_00323 3.6e-66 I alpha/beta hydrolase fold
GPFHHGKB_00324 2.8e-26
GPFHHGKB_00325 2.8e-58 3.6.1.27 I phosphatase
GPFHHGKB_00326 1.6e-22
GPFHHGKB_00327 4.5e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GPFHHGKB_00328 6.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
GPFHHGKB_00329 3.1e-27 cspC K Cold shock protein
GPFHHGKB_00330 4.3e-82 thrE S Putative threonine/serine exporter
GPFHHGKB_00331 6.3e-49 S Threonine/Serine exporter, ThrE
GPFHHGKB_00332 1.2e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GPFHHGKB_00333 1.6e-85 S Sucrose-6F-phosphate phosphohydrolase
GPFHHGKB_00334 1.9e-34 trxA O Belongs to the thioredoxin family
GPFHHGKB_00335 9.4e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPFHHGKB_00336 2e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPFHHGKB_00337 3.3e-65 degV S Uncharacterised protein, DegV family COG1307
GPFHHGKB_00339 4.3e-54 queT S QueT transporter
GPFHHGKB_00340 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
GPFHHGKB_00341 1.2e-100 IQ Enoyl-(Acyl carrier protein) reductase
GPFHHGKB_00342 1e-111 argE 3.5.1.18 E Peptidase dimerisation domain
GPFHHGKB_00343 1.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPFHHGKB_00344 6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GPFHHGKB_00345 1e-87 S Alpha beta hydrolase
GPFHHGKB_00346 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPFHHGKB_00347 1.2e-140 V MatE
GPFHHGKB_00348 2.6e-155 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
GPFHHGKB_00349 2.4e-65 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPFHHGKB_00350 1.3e-96 V ABC transporter
GPFHHGKB_00351 1.6e-131 bacI V MacB-like periplasmic core domain
GPFHHGKB_00352 9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPFHHGKB_00353 1.7e-26
GPFHHGKB_00354 2.1e-180 yhdP S Transporter associated domain
GPFHHGKB_00355 2.7e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
GPFHHGKB_00356 0.0 L Helicase C-terminal domain protein
GPFHHGKB_00357 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPFHHGKB_00358 3.7e-212 yfnA E Amino Acid
GPFHHGKB_00359 2.4e-53 zur P Belongs to the Fur family
GPFHHGKB_00360 3.1e-09 3.2.1.14 GH18
GPFHHGKB_00361 5e-98
GPFHHGKB_00362 1.3e-09
GPFHHGKB_00363 3.3e-103 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPFHHGKB_00364 1.5e-99 glnH ET ABC transporter
GPFHHGKB_00365 1.2e-85 gluC P ABC transporter permease
GPFHHGKB_00366 9.6e-78 glnP P ABC transporter permease
GPFHHGKB_00367 9.2e-180 clcA P chloride
GPFHHGKB_00368 2.8e-19 secG U Preprotein translocase
GPFHHGKB_00369 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GPFHHGKB_00370 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GPFHHGKB_00371 3.1e-42 yxjI
GPFHHGKB_00372 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
GPFHHGKB_00373 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPFHHGKB_00374 2.6e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GPFHHGKB_00375 8.4e-57 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
GPFHHGKB_00376 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
GPFHHGKB_00377 2.1e-115 murB 1.3.1.98 M Cell wall formation
GPFHHGKB_00378 2.4e-71 S Protein of unknown function (DUF1361)
GPFHHGKB_00379 2.9e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPFHHGKB_00380 5.3e-68 ybbR S YbbR-like protein
GPFHHGKB_00381 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPFHHGKB_00382 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
GPFHHGKB_00383 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
GPFHHGKB_00384 4.2e-21 cutC P Participates in the control of copper homeostasis
GPFHHGKB_00385 8.1e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPFHHGKB_00386 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPFHHGKB_00387 9.2e-99 rrmA 2.1.1.187 H Methyltransferase
GPFHHGKB_00388 2.2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GPFHHGKB_00389 1.3e-283 ftsK D Belongs to the FtsK SpoIIIE SftA family
GPFHHGKB_00390 1.6e-108 ymfF S Peptidase M16 inactive domain protein
GPFHHGKB_00391 2.4e-149 ymfH S Peptidase M16
GPFHHGKB_00392 2.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
GPFHHGKB_00393 2.9e-64 ymfM S Helix-turn-helix domain
GPFHHGKB_00394 7.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPFHHGKB_00395 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPFHHGKB_00396 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
GPFHHGKB_00397 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPFHHGKB_00398 5.4e-225 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPFHHGKB_00399 5.6e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GPFHHGKB_00400 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GPFHHGKB_00401 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPFHHGKB_00402 5.6e-206 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GPFHHGKB_00403 1.8e-12 yajC U Preprotein translocase
GPFHHGKB_00404 3e-125 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
GPFHHGKB_00405 7.2e-91 L Transposase, IS605 OrfB family
GPFHHGKB_00406 1e-54 tlpA2 L Transposase IS200 like
GPFHHGKB_00407 1.4e-88 L Belongs to the 'phage' integrase family
GPFHHGKB_00409 1.3e-190 XK27_11280 S Psort location CytoplasmicMembrane, score
GPFHHGKB_00410 6.6e-157 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GPFHHGKB_00411 3.4e-109 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
GPFHHGKB_00412 2.2e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
GPFHHGKB_00413 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
GPFHHGKB_00414 7.5e-216 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
GPFHHGKB_00415 1.5e-188 iolF EGP Major facilitator Superfamily
GPFHHGKB_00416 1.1e-75 rhaR K helix_turn_helix, arabinose operon control protein
GPFHHGKB_00417 3.8e-50 S Membrane
GPFHHGKB_00418 1.3e-180 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
GPFHHGKB_00419 3.1e-57 yvbG U MarC family integral membrane protein
GPFHHGKB_00420 6.4e-16 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
GPFHHGKB_00421 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
GPFHHGKB_00422 7.1e-148 yedE S Sulphur transport
GPFHHGKB_00423 2.7e-100 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
GPFHHGKB_00424 2.6e-175 rnfC C RnfC Barrel sandwich hybrid domain
GPFHHGKB_00425 9e-29 yitW S Iron-sulfur cluster assembly protein
GPFHHGKB_00426 2.4e-110 selA 2.9.1.1 H Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
GPFHHGKB_00427 5.1e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
GPFHHGKB_00428 2e-136 selB J Elongation factor SelB, winged helix
GPFHHGKB_00429 4.5e-08 S Protein of unknown function (DUF3343)
GPFHHGKB_00430 9e-49 yedF O Belongs to the sulfur carrier protein TusA family
GPFHHGKB_00431 5.3e-223 ybeC E amino acid
GPFHHGKB_00432 4.4e-94 XK27_00825 S Sulfite exporter TauE/SafE
GPFHHGKB_00433 7e-144 5.1.1.4 E Proline racemase
GPFHHGKB_00434 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
GPFHHGKB_00435 4.7e-73 prdD S An automated process has identified a potential problem with this gene model
GPFHHGKB_00436 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
GPFHHGKB_00437 5.8e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
GPFHHGKB_00438 3.2e-26 S Psort location Cytoplasmic, score
GPFHHGKB_00439 9.5e-235 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
GPFHHGKB_00441 3.2e-115 ynjE 2.8.1.11 P Rhodanese Homology Domain
GPFHHGKB_00442 2e-16 yeeD O Belongs to the sulfur carrier protein TusA family
GPFHHGKB_00443 6.9e-62 yeeE S Sulphur transport
GPFHHGKB_00444 3e-105 yraQ S Predicted permease
GPFHHGKB_00445 3e-124 yvgN C Aldo keto reductase
GPFHHGKB_00446 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GPFHHGKB_00447 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GPFHHGKB_00448 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
GPFHHGKB_00449 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPFHHGKB_00450 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GPFHHGKB_00451 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPFHHGKB_00452 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GPFHHGKB_00453 1.4e-54
GPFHHGKB_00454 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPFHHGKB_00455 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPFHHGKB_00456 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPFHHGKB_00457 9.7e-46 nrdI F NrdI Flavodoxin like
GPFHHGKB_00458 2.7e-27 nrdH O Glutaredoxin
GPFHHGKB_00459 1.9e-75 rsmC 2.1.1.172 J Methyltransferase
GPFHHGKB_00460 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GPFHHGKB_00461 1.5e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPFHHGKB_00462 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPFHHGKB_00463 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPFHHGKB_00464 9.2e-29 yaaL S Protein of unknown function (DUF2508)
GPFHHGKB_00465 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPFHHGKB_00466 2.3e-83 holB 2.7.7.7 L DNA polymerase III
GPFHHGKB_00467 1.4e-40 yabA L Involved in initiation control of chromosome replication
GPFHHGKB_00468 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPFHHGKB_00469 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
GPFHHGKB_00470 2.7e-140 ansA 3.5.1.1 EJ Asparaginase
GPFHHGKB_00471 3.7e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
GPFHHGKB_00472 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
GPFHHGKB_00473 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPFHHGKB_00474 1.2e-253 uup S ABC transporter, ATP-binding protein
GPFHHGKB_00475 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GPFHHGKB_00476 3.1e-33 S CAAX protease self-immunity
GPFHHGKB_00477 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPFHHGKB_00478 1.8e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GPFHHGKB_00479 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
GPFHHGKB_00480 1.4e-296 ydaO E amino acid
GPFHHGKB_00481 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
GPFHHGKB_00482 5.4e-128 comFA L Helicase C-terminal domain protein
GPFHHGKB_00483 1e-45 comFC S Competence protein
GPFHHGKB_00484 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPFHHGKB_00485 3.6e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPFHHGKB_00486 5.5e-243 lysP E amino acid
GPFHHGKB_00487 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
GPFHHGKB_00488 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GPFHHGKB_00489 1.2e-13 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPFHHGKB_00490 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
GPFHHGKB_00491 7.6e-83 lysR5 K LysR substrate binding domain
GPFHHGKB_00492 1.7e-119 yxaA S membrane transporter protein
GPFHHGKB_00493 2.6e-32 ywjH S Protein of unknown function (DUF1634)
GPFHHGKB_00494 7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GPFHHGKB_00495 1.7e-225 pipD E Dipeptidase
GPFHHGKB_00496 1.8e-21 K helix_turn_helix multiple antibiotic resistance protein
GPFHHGKB_00497 7.4e-165 EGP Major facilitator Superfamily
GPFHHGKB_00498 4.7e-81 S L,D-transpeptidase catalytic domain
GPFHHGKB_00499 1.9e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GPFHHGKB_00500 4.3e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPFHHGKB_00501 7.2e-27 ydiI Q Thioesterase superfamily
GPFHHGKB_00502 5.6e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
GPFHHGKB_00503 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
GPFHHGKB_00504 6.4e-114 degV S EDD domain protein, DegV family
GPFHHGKB_00505 3.4e-226 cadA P P-type ATPase
GPFHHGKB_00506 1.8e-254 E Amino acid permease
GPFHHGKB_00507 2.1e-83 S Membrane
GPFHHGKB_00508 1.6e-49 cps3F
GPFHHGKB_00509 3.3e-283 fruA 2.7.1.202 GT Phosphotransferase System
GPFHHGKB_00510 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GPFHHGKB_00511 9e-88 fruR K DeoR C terminal sensor domain
GPFHHGKB_00512 6.7e-219 XK27_08635 S UPF0210 protein
GPFHHGKB_00513 4.1e-27 gcvR T Belongs to the UPF0237 family
GPFHHGKB_00514 2.3e-38
GPFHHGKB_00515 1.1e-76 E GDSL-like Lipase/Acylhydrolase family
GPFHHGKB_00516 9.2e-56 S Protein of unknown function (DUF975)
GPFHHGKB_00517 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
GPFHHGKB_00518 8.8e-230 lpdA 1.8.1.4 C Dehydrogenase
GPFHHGKB_00519 1.4e-178 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPFHHGKB_00520 2.8e-166 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
GPFHHGKB_00521 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
GPFHHGKB_00524 2.3e-34 S Protein of unknown function (DUF4256)
GPFHHGKB_00525 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
GPFHHGKB_00526 2.4e-31 metI U ABC transporter permease
GPFHHGKB_00527 2.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPFHHGKB_00529 3.3e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
GPFHHGKB_00530 1.3e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GPFHHGKB_00531 2.3e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
GPFHHGKB_00532 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
GPFHHGKB_00533 3e-84 drgA C nitroreductase
GPFHHGKB_00534 8.8e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
GPFHHGKB_00535 9.6e-68 metI P ABC transporter permease
GPFHHGKB_00536 1.5e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPFHHGKB_00537 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
GPFHHGKB_00538 1e-143 2.1.1.14 E methionine synthase, vitamin-B12 independent
GPFHHGKB_00539 1.4e-45 yphJ 4.1.1.44 S decarboxylase
GPFHHGKB_00540 1.1e-55 yphH S Cupin domain
GPFHHGKB_00541 2.4e-46 C Flavodoxin
GPFHHGKB_00542 3.6e-56 S CAAX protease self-immunity
GPFHHGKB_00543 1.2e-102 pgm3 G phosphoglycerate mutase
GPFHHGKB_00544 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GPFHHGKB_00545 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPFHHGKB_00546 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPFHHGKB_00547 7.4e-67 M ErfK YbiS YcfS YnhG
GPFHHGKB_00548 1e-107 XK27_08845 S ABC transporter, ATP-binding protein
GPFHHGKB_00549 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
GPFHHGKB_00550 7.8e-132 ABC-SBP S ABC transporter
GPFHHGKB_00551 1.4e-158 potD P ABC transporter
GPFHHGKB_00552 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
GPFHHGKB_00553 9.5e-120 potB P ABC transporter permease
GPFHHGKB_00554 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GPFHHGKB_00555 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GPFHHGKB_00556 1.6e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
GPFHHGKB_00557 1.5e-235 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPFHHGKB_00558 3.9e-13 S Enterocin A Immunity
GPFHHGKB_00559 2.2e-16 pspC KT PspC domain
GPFHHGKB_00560 2.4e-16 S Putative adhesin
GPFHHGKB_00561 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
GPFHHGKB_00562 8.1e-38 K transcriptional regulator PadR family
GPFHHGKB_00563 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
GPFHHGKB_00564 4.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
GPFHHGKB_00565 2.4e-164 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPFHHGKB_00566 1.1e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPFHHGKB_00567 3.5e-70 mltD CBM50 M NlpC P60 family protein
GPFHHGKB_00568 1.8e-52 manO S Domain of unknown function (DUF956)
GPFHHGKB_00569 2.1e-147 manN G system, mannose fructose sorbose family IID component
GPFHHGKB_00570 6.4e-116 manY G PTS system sorbose-specific iic component
GPFHHGKB_00571 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
GPFHHGKB_00572 4.1e-80 rbsB G sugar-binding domain protein
GPFHHGKB_00573 5.1e-99 baeS T Histidine kinase
GPFHHGKB_00574 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
GPFHHGKB_00575 1.8e-120 G Bacterial extracellular solute-binding protein
GPFHHGKB_00576 9.1e-71 S Protein of unknown function (DUF554)
GPFHHGKB_00577 1e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPFHHGKB_00578 1.9e-32 merR K MerR HTH family regulatory protein
GPFHHGKB_00579 2.1e-197 lmrB EGP Major facilitator Superfamily
GPFHHGKB_00580 7e-34 S Domain of unknown function (DUF4811)
GPFHHGKB_00581 4.3e-41 S CAAX protease self-immunity
GPFHHGKB_00582 1.3e-60 yceE S haloacid dehalogenase-like hydrolase
GPFHHGKB_00583 7.6e-74 glcR K DeoR C terminal sensor domain
GPFHHGKB_00584 1.7e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GPFHHGKB_00585 1.3e-183 lmrB EGP Major facilitator Superfamily
GPFHHGKB_00586 2.1e-54 bioY S BioY family
GPFHHGKB_00587 1.4e-94 S Predicted membrane protein (DUF2207)
GPFHHGKB_00588 1.4e-19
GPFHHGKB_00589 4.4e-37 M Glycosyltransferase group 2 family protein
GPFHHGKB_00590 7.4e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GPFHHGKB_00591 2.8e-58 ktrA P TrkA-N domain
GPFHHGKB_00592 1.2e-114 ntpJ P Potassium uptake protein
GPFHHGKB_00593 5.3e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
GPFHHGKB_00594 1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
GPFHHGKB_00595 3.5e-216 scrB 3.2.1.26 GH32 G invertase
GPFHHGKB_00596 1.7e-147 scrR K helix_turn _helix lactose operon repressor
GPFHHGKB_00603 5.1e-08
GPFHHGKB_00609 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
GPFHHGKB_00610 9.2e-48 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GPFHHGKB_00611 1.2e-67 coiA 3.6.4.12 S Competence protein
GPFHHGKB_00612 9.6e-232 pepF E oligoendopeptidase F
GPFHHGKB_00613 3.9e-41 yjbH Q Thioredoxin
GPFHHGKB_00614 1.4e-97 pstS P Phosphate
GPFHHGKB_00615 5.4e-119 pstC P probably responsible for the translocation of the substrate across the membrane
GPFHHGKB_00616 3e-122 pstA P Phosphate transport system permease protein PstA
GPFHHGKB_00617 1e-113 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPFHHGKB_00618 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPFHHGKB_00619 2.7e-56 P Plays a role in the regulation of phosphate uptake
GPFHHGKB_00620 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
GPFHHGKB_00621 1.1e-79 S VIT family
GPFHHGKB_00622 9.4e-84 S membrane
GPFHHGKB_00623 2.8e-40 M1-874 K Domain of unknown function (DUF1836)
GPFHHGKB_00624 2.3e-65 hly S protein, hemolysin III
GPFHHGKB_00625 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
GPFHHGKB_00626 4.5e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPFHHGKB_00629 3e-14
GPFHHGKB_00630 5.1e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GPFHHGKB_00631 1.3e-158 ccpA K catabolite control protein A
GPFHHGKB_00632 3.7e-42 S VanZ like family
GPFHHGKB_00633 4.3e-119 yebC K Transcriptional regulatory protein
GPFHHGKB_00634 1e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPFHHGKB_00635 1.1e-120 comGA NU Type II IV secretion system protein
GPFHHGKB_00636 8.8e-99 comGB NU type II secretion system
GPFHHGKB_00637 7.9e-27 comGC U competence protein ComGC
GPFHHGKB_00638 1.5e-13
GPFHHGKB_00640 4.1e-11 S Putative Competence protein ComGF
GPFHHGKB_00642 2.4e-87 ytxK 2.1.1.72 L N-6 DNA Methylase
GPFHHGKB_00643 2.3e-182 cycA E Amino acid permease
GPFHHGKB_00644 6.6e-57 S Calcineurin-like phosphoesterase
GPFHHGKB_00645 1.9e-53 yutD S Protein of unknown function (DUF1027)
GPFHHGKB_00646 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GPFHHGKB_00647 3.5e-32 S Protein of unknown function (DUF1461)
GPFHHGKB_00648 8.8e-92 dedA S SNARE associated Golgi protein
GPFHHGKB_00649 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GPFHHGKB_00650 8.8e-50 yugI 5.3.1.9 J general stress protein
GPFHHGKB_00651 3e-69 ybhL S Belongs to the BI1 family
GPFHHGKB_00652 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
GPFHHGKB_00653 3.8e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GPFHHGKB_00654 1.3e-238 sftA D Belongs to the FtsK SpoIIIE SftA family
GPFHHGKB_00655 1.8e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPFHHGKB_00656 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GPFHHGKB_00657 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GPFHHGKB_00658 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
GPFHHGKB_00659 8.4e-72 ecsB U ABC transporter
GPFHHGKB_00660 9.8e-95 ecsA V ABC transporter, ATP-binding protein
GPFHHGKB_00661 7e-53 hit FG histidine triad
GPFHHGKB_00663 1.5e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GPFHHGKB_00664 7.3e-127 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPFHHGKB_00665 2e-21 yheA S Belongs to the UPF0342 family
GPFHHGKB_00666 1.5e-284 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPFHHGKB_00667 1.7e-117 sip L Belongs to the 'phage' integrase family
GPFHHGKB_00668 8.9e-13 K Transcriptional regulator
GPFHHGKB_00669 9.1e-08 S Helix-turn-helix domain
GPFHHGKB_00670 4.4e-38 K COG3617 Prophage antirepressor
GPFHHGKB_00675 7.4e-20
GPFHHGKB_00677 1.7e-37 ybl78 L Conserved phage C-terminus (Phg_2220_C)
GPFHHGKB_00678 9.1e-08 arpU S Phage transcriptional regulator, ArpU family
GPFHHGKB_00680 4.4e-07
GPFHHGKB_00681 2.3e-16
GPFHHGKB_00684 2.6e-86 ykuT M mechanosensitive ion channel
GPFHHGKB_00685 2.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GPFHHGKB_00686 3e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GPFHHGKB_00687 1.5e-45 ykuL S CBS domain
GPFHHGKB_00688 1.3e-118 gla U Major intrinsic protein
GPFHHGKB_00689 6e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GPFHHGKB_00690 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
GPFHHGKB_00691 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPFHHGKB_00692 5.6e-127
GPFHHGKB_00693 5.1e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GPFHHGKB_00694 1.6e-42 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
GPFHHGKB_00695 2.3e-31 K Transcriptional regulator
GPFHHGKB_00696 2e-104 ybhR V ABC transporter
GPFHHGKB_00697 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
GPFHHGKB_00698 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
GPFHHGKB_00699 8.8e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPFHHGKB_00700 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPFHHGKB_00701 2.2e-270 helD 3.6.4.12 L DNA helicase
GPFHHGKB_00703 1.3e-114 htpX O Belongs to the peptidase M48B family
GPFHHGKB_00704 8.7e-72 lemA S LemA family
GPFHHGKB_00705 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
GPFHHGKB_00706 3.2e-45 yjcF K protein acetylation
GPFHHGKB_00708 3.9e-254 yfiC V ABC transporter
GPFHHGKB_00709 9.9e-223 lmrA V ABC transporter, ATP-binding protein
GPFHHGKB_00710 5.8e-35 K Bacterial regulatory proteins, tetR family
GPFHHGKB_00711 9.5e-246 yhcA V ABC transporter, ATP-binding protein
GPFHHGKB_00712 2.6e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPFHHGKB_00713 1e-146 G Transporter, major facilitator family protein
GPFHHGKB_00714 5.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
GPFHHGKB_00715 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
GPFHHGKB_00716 2.5e-113 K response regulator
GPFHHGKB_00717 3.4e-89 patB 4.4.1.8 E Aminotransferase, class I
GPFHHGKB_00718 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GPFHHGKB_00719 0.0 pacL 3.6.3.8 P P-type ATPase
GPFHHGKB_00720 1.5e-108 3.1.4.46 C phosphodiesterase
GPFHHGKB_00721 1.6e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GPFHHGKB_00722 4.7e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
GPFHHGKB_00723 7e-81 noc K Belongs to the ParB family
GPFHHGKB_00724 6.5e-118 soj D Sporulation initiation inhibitor
GPFHHGKB_00725 4.1e-108 spo0J K Belongs to the ParB family
GPFHHGKB_00726 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
GPFHHGKB_00727 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GPFHHGKB_00728 2.5e-53 XK27_01040 S Protein of unknown function (DUF1129)
GPFHHGKB_00729 1.2e-13 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GPFHHGKB_00730 3.4e-38
GPFHHGKB_00731 1.8e-59 V Abi-like protein
GPFHHGKB_00732 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
GPFHHGKB_00733 7.7e-99 fhuC P ABC transporter
GPFHHGKB_00734 2.8e-95 znuB U ABC 3 transport family
GPFHHGKB_00735 1.5e-55 S ECF transporter, substrate-specific component
GPFHHGKB_00736 2e-101 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPFHHGKB_00737 5.8e-90 S NADPH-dependent FMN reductase
GPFHHGKB_00738 2.7e-27 K helix_turn_helix, mercury resistance
GPFHHGKB_00739 6.5e-66 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPFHHGKB_00741 5.8e-154 EGP Major facilitator Superfamily
GPFHHGKB_00742 3.3e-57 S Haloacid dehalogenase-like hydrolase
GPFHHGKB_00743 9.1e-89 yvyE 3.4.13.9 S YigZ family
GPFHHGKB_00744 9.5e-38 S CAAX protease self-immunity
GPFHHGKB_00745 8.4e-116 cps1D M Domain of unknown function (DUF4422)
GPFHHGKB_00746 1e-62 S Glycosyltransferase like family 2
GPFHHGKB_00747 1.5e-137 tetA EGP Major facilitator Superfamily
GPFHHGKB_00748 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
GPFHHGKB_00749 6.4e-213 yjeM E Amino Acid
GPFHHGKB_00750 1.9e-190 glnPH2 P ABC transporter permease
GPFHHGKB_00751 1.5e-111 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPFHHGKB_00752 3.6e-14
GPFHHGKB_00753 4.9e-97 S Psort location CytoplasmicMembrane, score
GPFHHGKB_00754 1.1e-157 XK27_09615 S reductase
GPFHHGKB_00755 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
GPFHHGKB_00756 7.3e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GPFHHGKB_00757 6.2e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GPFHHGKB_00758 1.1e-309 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GPFHHGKB_00760 8.1e-154 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
GPFHHGKB_00761 2.9e-62 S Glycosyltransferase like family 2
GPFHHGKB_00762 2.5e-195 glf 5.4.99.9 M UDP-galactopyranose mutase
GPFHHGKB_00763 1.5e-38 S Acyltransferase family
GPFHHGKB_00764 2.6e-43 S Peptidase_C39 like family
GPFHHGKB_00765 2.5e-63 M Glycosyltransferase like family 2
GPFHHGKB_00766 3.7e-74 M LicD family
GPFHHGKB_00767 1.5e-57 cps3F
GPFHHGKB_00768 7.5e-93 M transferase activity, transferring glycosyl groups
GPFHHGKB_00769 2.8e-76 waaB GT4 M Glycosyl transferases group 1
GPFHHGKB_00770 2.4e-92 M Core-2/I-Branching enzyme
GPFHHGKB_00771 2.7e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPFHHGKB_00772 9.2e-65 rny D Peptidase family M23
GPFHHGKB_00774 2.6e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GPFHHGKB_00775 3.3e-165 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPFHHGKB_00776 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GPFHHGKB_00777 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPFHHGKB_00778 9.5e-08 alkD L DNA alkylation repair enzyme
GPFHHGKB_00779 2.4e-54 alkD L DNA alkylation repair enzyme
GPFHHGKB_00780 3.8e-136 EG EamA-like transporter family
GPFHHGKB_00781 3.6e-150 S Tetratricopeptide repeat protein
GPFHHGKB_00782 3.4e-204 hisS 6.1.1.21 J histidyl-tRNA synthetase
GPFHHGKB_00783 8.7e-299 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GPFHHGKB_00784 7e-127 corA P CorA-like Mg2+ transporter protein
GPFHHGKB_00786 1.1e-160 nhaC C Na H antiporter NhaC
GPFHHGKB_00787 4.2e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPFHHGKB_00788 7.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
GPFHHGKB_00790 4.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPFHHGKB_00791 1.2e-155 iscS 2.8.1.7 E Aminotransferase class V
GPFHHGKB_00792 3.7e-41 XK27_04120 S Putative amino acid metabolism
GPFHHGKB_00793 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GPFHHGKB_00794 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GPFHHGKB_00795 4.3e-15 S Protein of unknown function (DUF2929)
GPFHHGKB_00796 0.0 dnaE 2.7.7.7 L DNA polymerase
GPFHHGKB_00797 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GPFHHGKB_00798 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GPFHHGKB_00800 1e-39 ypaA S Protein of unknown function (DUF1304)
GPFHHGKB_00801 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GPFHHGKB_00802 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPFHHGKB_00803 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPFHHGKB_00804 3.1e-95 yeaN P Major Facilitator Superfamily
GPFHHGKB_00805 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GPFHHGKB_00806 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GPFHHGKB_00807 1.7e-66 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
GPFHHGKB_00808 3.5e-86 K response regulator
GPFHHGKB_00809 1e-84 phoR 2.7.13.3 T Histidine kinase
GPFHHGKB_00810 4.1e-08 KT PspC domain protein
GPFHHGKB_00811 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
GPFHHGKB_00812 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GPFHHGKB_00813 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPFHHGKB_00814 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GPFHHGKB_00815 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GPFHHGKB_00816 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GPFHHGKB_00817 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GPFHHGKB_00818 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
GPFHHGKB_00819 7.5e-126 rapZ S Displays ATPase and GTPase activities
GPFHHGKB_00820 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GPFHHGKB_00821 1.8e-149 whiA K May be required for sporulation
GPFHHGKB_00822 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GPFHHGKB_00824 2.9e-137 cggR K Putative sugar-binding domain
GPFHHGKB_00825 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPFHHGKB_00826 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GPFHHGKB_00827 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPFHHGKB_00828 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GPFHHGKB_00832 5.4e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPFHHGKB_00833 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GPFHHGKB_00834 5.1e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPFHHGKB_00835 1.6e-160 camS S sex pheromone
GPFHHGKB_00836 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPFHHGKB_00837 2.3e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GPFHHGKB_00838 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPFHHGKB_00839 9.8e-146 yegS 2.7.1.107 G Lipid kinase
GPFHHGKB_00840 3.4e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPFHHGKB_00841 3.7e-122 L Mrr N-terminal domain
GPFHHGKB_00842 2.1e-17
GPFHHGKB_00843 0.0 2.1.1.72 V type I restriction-modification system
GPFHHGKB_00844 6.4e-70 hsdS 3.1.21.3 V COG0732 Restriction endonuclease S subunits
GPFHHGKB_00845 0.0 hsdR 3.1.21.3 L COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
GPFHHGKB_00846 2.1e-07
GPFHHGKB_00847 1.9e-233 L AAA ATPase domain
GPFHHGKB_00848 8.6e-151 3.6.4.12 L UvrD/REP helicase N-terminal domain
GPFHHGKB_00849 2.1e-56 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
GPFHHGKB_00850 7e-26 S Domain of unknown function (DUF3841)
GPFHHGKB_00851 2.2e-87 spoVK O ATPase family associated with various cellular activities (AAA)
GPFHHGKB_00852 3.3e-29 M Glycosyl transferases group 1
GPFHHGKB_00853 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
GPFHHGKB_00854 7.4e-40 K Transcriptional regulator
GPFHHGKB_00855 5.4e-31 S CHY zinc finger
GPFHHGKB_00856 1.5e-85 1.1.1.1 C Zinc-binding dehydrogenase
GPFHHGKB_00858 3.4e-41 S Protein of unknown function (DUF1211)
GPFHHGKB_00859 1.8e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
GPFHHGKB_00861 3.3e-41 wecD M Acetyltransferase (GNAT) family
GPFHHGKB_00862 1.4e-77 cps2D 5.1.3.2 M RmlD substrate binding domain
GPFHHGKB_00863 1.5e-66 H Methyltransferase domain
GPFHHGKB_00865 3.7e-16 K DNA-templated transcription, initiation
GPFHHGKB_00869 9.4e-94 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
GPFHHGKB_00870 1e-198 L transposition, DNA-mediated
GPFHHGKB_00872 1.8e-12
GPFHHGKB_00873 7.9e-22 S PIN domain
GPFHHGKB_00874 5.3e-12 D Antitoxin component of a toxin-antitoxin (TA) module
GPFHHGKB_00875 1.2e-88 mesE M Transport protein ComB
GPFHHGKB_00876 1.1e-273 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GPFHHGKB_00879 2.5e-56 K LytTr DNA-binding domain
GPFHHGKB_00880 1.2e-58 2.7.13.3 T GHKL domain
GPFHHGKB_00884 3.1e-16
GPFHHGKB_00886 9.4e-08
GPFHHGKB_00887 6.6e-19
GPFHHGKB_00888 5.9e-39 blpT
GPFHHGKB_00889 3e-87 S Haloacid dehalogenase-like hydrolase
GPFHHGKB_00890 4.6e-15
GPFHHGKB_00893 2.1e-21 XK27_09445 S Domain of unknown function (DUF1827)
GPFHHGKB_00894 1.7e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
GPFHHGKB_00895 0.0 rafA 3.2.1.22 G alpha-galactosidase
GPFHHGKB_00896 1.4e-201 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GPFHHGKB_00897 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GPFHHGKB_00898 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPFHHGKB_00899 7.7e-111 galR K Transcriptional regulator
GPFHHGKB_00900 8.9e-289 lacS G Transporter
GPFHHGKB_00901 0.0 lacL 3.2.1.23 G -beta-galactosidase
GPFHHGKB_00902 9.8e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPFHHGKB_00903 2.3e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GPFHHGKB_00904 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GPFHHGKB_00905 5.3e-92 yueF S AI-2E family transporter
GPFHHGKB_00906 2.6e-97 ygaC J Belongs to the UPF0374 family
GPFHHGKB_00907 8.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPFHHGKB_00908 7.6e-69 recX 2.4.1.337 GT4 S Regulatory protein RecX
GPFHHGKB_00909 2.3e-19 sigH K DNA-templated transcription, initiation
GPFHHGKB_00910 1.6e-22 S Cytochrome B5
GPFHHGKB_00911 5e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
GPFHHGKB_00912 1.7e-59
GPFHHGKB_00913 3.7e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GPFHHGKB_00914 2.5e-155 nrnB S DHHA1 domain
GPFHHGKB_00915 3.1e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
GPFHHGKB_00917 8e-64 srtA 3.4.22.70 M sortase family
GPFHHGKB_00918 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GPFHHGKB_00919 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GPFHHGKB_00920 9.6e-35
GPFHHGKB_00921 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPFHHGKB_00922 4.4e-156 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPFHHGKB_00923 3.3e-96 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPFHHGKB_00924 2.4e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
GPFHHGKB_00925 1.1e-39 ybjQ S Belongs to the UPF0145 family
GPFHHGKB_00926 8.2e-07
GPFHHGKB_00927 3e-95 V ABC transporter, ATP-binding protein
GPFHHGKB_00928 1.1e-41 gntR1 K Transcriptional regulator, GntR family
GPFHHGKB_00929 1.9e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
GPFHHGKB_00930 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPFHHGKB_00931 3.8e-262 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
GPFHHGKB_00932 1.7e-107 terC P Integral membrane protein TerC family
GPFHHGKB_00933 1.6e-38 K Transcriptional regulator
GPFHHGKB_00934 9.8e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
GPFHHGKB_00935 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPFHHGKB_00936 4.5e-102 tcyB E ABC transporter
GPFHHGKB_00938 3.7e-13 ponA V the current gene model (or a revised gene model) may contain a frame shift
GPFHHGKB_00939 1e-187 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GPFHHGKB_00940 7.8e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GPFHHGKB_00941 2e-209 mtlR K Mga helix-turn-helix domain
GPFHHGKB_00942 4.9e-176 yjcE P Sodium proton antiporter
GPFHHGKB_00943 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GPFHHGKB_00944 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
GPFHHGKB_00945 5.6e-69 dhaL 2.7.1.121 S Dak2
GPFHHGKB_00946 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
GPFHHGKB_00947 7.9e-113 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
GPFHHGKB_00948 1.7e-61 K Bacterial regulatory proteins, tetR family
GPFHHGKB_00949 8.5e-209 brnQ U Component of the transport system for branched-chain amino acids
GPFHHGKB_00951 1.7e-111 endA F DNA RNA non-specific endonuclease
GPFHHGKB_00952 1.1e-75 XK27_02070 S Nitroreductase family
GPFHHGKB_00953 4.5e-192 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
GPFHHGKB_00954 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
GPFHHGKB_00955 8e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
GPFHHGKB_00956 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GPFHHGKB_00957 5.5e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
GPFHHGKB_00958 5.1e-77 azlC E branched-chain amino acid
GPFHHGKB_00959 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
GPFHHGKB_00960 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
GPFHHGKB_00961 1.6e-55 jag S R3H domain protein
GPFHHGKB_00962 9.1e-54 K Transcriptional regulator C-terminal region
GPFHHGKB_00963 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
GPFHHGKB_00964 3.7e-287 pepO 3.4.24.71 O Peptidase family M13
GPFHHGKB_00965 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
GPFHHGKB_00966 2.1e-07 S SdpI/YhfL protein family
GPFHHGKB_00967 7.8e-72 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
GPFHHGKB_00968 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
GPFHHGKB_00969 5.7e-41 wecD K Acetyltransferase GNAT Family
GPFHHGKB_00971 5e-255 XK27_06780 V ABC transporter permease
GPFHHGKB_00972 1.1e-95 XK27_06785 V ABC transporter, ATP-binding protein
GPFHHGKB_00974 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
GPFHHGKB_00975 3.8e-66 ybbL S ABC transporter
GPFHHGKB_00976 6.2e-163 oxlT P Major Facilitator Superfamily
GPFHHGKB_00977 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GPFHHGKB_00978 4.1e-47 S Short repeat of unknown function (DUF308)
GPFHHGKB_00979 1.8e-30 tetR K Transcriptional regulator C-terminal region
GPFHHGKB_00980 1.3e-150 yfeX P Peroxidase
GPFHHGKB_00981 1.5e-16 S Protein of unknown function (DUF3021)
GPFHHGKB_00982 2.6e-39 K LytTr DNA-binding domain
GPFHHGKB_00983 1.2e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
GPFHHGKB_00984 2.9e-209 mmuP E amino acid
GPFHHGKB_00985 5.9e-15 psiE S Phosphate-starvation-inducible E
GPFHHGKB_00986 9.7e-156 oppF P Belongs to the ABC transporter superfamily
GPFHHGKB_00987 1.3e-180 oppD P Belongs to the ABC transporter superfamily
GPFHHGKB_00988 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPFHHGKB_00989 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPFHHGKB_00990 3.1e-202 oppA E ABC transporter, substratebinding protein
GPFHHGKB_00991 4.5e-218 yifK E Amino acid permease
GPFHHGKB_00992 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPFHHGKB_00993 1.8e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
GPFHHGKB_00994 6.5e-66 pgm3 G phosphoglycerate mutase family
GPFHHGKB_00995 1e-252 ctpA 3.6.3.54 P P-type ATPase
GPFHHGKB_00996 1.9e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GPFHHGKB_00997 6.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GPFHHGKB_00998 1.6e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GPFHHGKB_00999 5.4e-181 EG GntP family permease
GPFHHGKB_01000 6.5e-116 KT Putative sugar diacid recognition
GPFHHGKB_01001 1.8e-22 K transcriptional regulator
GPFHHGKB_01002 5.1e-33 hchA S intracellular protease amidase
GPFHHGKB_01003 1.1e-25 hchA S intracellular protease amidase
GPFHHGKB_01004 7.6e-133 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
GPFHHGKB_01005 1.5e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
GPFHHGKB_01006 2.5e-140 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPFHHGKB_01007 1.8e-171 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
GPFHHGKB_01008 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
GPFHHGKB_01009 1.6e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
GPFHHGKB_01010 1.2e-72 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
GPFHHGKB_01011 4.9e-130 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
GPFHHGKB_01012 1e-99 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GPFHHGKB_01013 9.5e-82 S Belongs to the UPF0246 family
GPFHHGKB_01014 7.9e-12 S CAAX protease self-immunity
GPFHHGKB_01015 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
GPFHHGKB_01016 5.1e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GPFHHGKB_01018 1.1e-59 uspA T Universal stress protein family
GPFHHGKB_01019 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
GPFHHGKB_01020 1.1e-25
GPFHHGKB_01021 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
GPFHHGKB_01022 5.2e-109 puuD S peptidase C26
GPFHHGKB_01023 6.8e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPFHHGKB_01024 7e-153 lsa S ABC transporter
GPFHHGKB_01025 9.4e-149 mepA V MATE efflux family protein
GPFHHGKB_01026 1.4e-38 arbx M family 8
GPFHHGKB_01028 2.4e-31 M Glycosyltransferase like family 2
GPFHHGKB_01029 1.1e-69 nss M transferase activity, transferring glycosyl groups
GPFHHGKB_01030 8.7e-37 M Glycosyl transferase family 8
GPFHHGKB_01031 3.5e-55 nss M transferase activity, transferring glycosyl groups
GPFHHGKB_01033 1.1e-18 arbx M family 8
GPFHHGKB_01034 1.4e-07 M Glycosyltransferase like family 2
GPFHHGKB_01035 2e-66 nss M transferase activity, transferring glycosyl groups
GPFHHGKB_01036 7.3e-109 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GPFHHGKB_01037 9e-34 yxaB 2.4.1.166 GT2 M Glycosyltransferase like family 2
GPFHHGKB_01038 1.8e-151 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GPFHHGKB_01039 2.5e-08 L Helix-turn-helix domain
GPFHHGKB_01041 1.4e-10 L Helix-turn-helix domain
GPFHHGKB_01042 8.6e-81 L hmm pf00665
GPFHHGKB_01044 5.4e-24 3.2.1.18 GH33 M Rib/alpha-like repeat
GPFHHGKB_01045 2.3e-26 K Transcriptional regulator, HxlR family
GPFHHGKB_01046 2.5e-170 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GPFHHGKB_01047 4e-101 ydhQ K UbiC transcription regulator-associated domain protein
GPFHHGKB_01048 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GPFHHGKB_01049 2.4e-82 pncA Q isochorismatase
GPFHHGKB_01050 4.6e-63 3.1.3.73 G phosphoglycerate mutase
GPFHHGKB_01051 9.5e-259 treB G phosphotransferase system
GPFHHGKB_01052 9.8e-84 treR K UTRA
GPFHHGKB_01053 8.2e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
GPFHHGKB_01054 1.4e-167 mdtG EGP Major facilitator Superfamily
GPFHHGKB_01056 2.6e-56 S peptidoglycan catabolic process
GPFHHGKB_01057 6.7e-151 M BCCT, betaine/carnitine/choline family transporter
GPFHHGKB_01058 1.1e-84 M Nucleotidyl transferase
GPFHHGKB_01059 2.2e-177 licA 2.7.1.89 M Choline/ethanolamine kinase
GPFHHGKB_01060 1.2e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GPFHHGKB_01061 2.6e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
GPFHHGKB_01062 6.9e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GPFHHGKB_01063 4.1e-177 thrC 4.2.3.1 E Threonine synthase
GPFHHGKB_01064 5.5e-157 XK27_08315 M Sulfatase
GPFHHGKB_01066 1.6e-145 pbuO_1 S Permease family
GPFHHGKB_01067 2.1e-43 2.7.7.65 T GGDEF domain
GPFHHGKB_01068 9.5e-128 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
GPFHHGKB_01069 1.3e-183
GPFHHGKB_01070 7.6e-206 S Protein conserved in bacteria
GPFHHGKB_01071 1.2e-201 ydaM M Glycosyl transferase family group 2
GPFHHGKB_01072 0.0 ydaN S Bacterial cellulose synthase subunit
GPFHHGKB_01073 1.4e-113 2.7.7.65 T diguanylate cyclase activity
GPFHHGKB_01074 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
GPFHHGKB_01075 3.5e-38 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
GPFHHGKB_01077 0.0 rafA 3.2.1.22 G alpha-galactosidase
GPFHHGKB_01078 1.2e-53 S Membrane
GPFHHGKB_01079 2.6e-64 K helix_turn_helix, arabinose operon control protein
GPFHHGKB_01080 2.3e-45
GPFHHGKB_01081 3.4e-205 pipD E Dipeptidase
GPFHHGKB_01082 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GPFHHGKB_01083 2.6e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GPFHHGKB_01084 5.6e-60 speG J Acetyltransferase (GNAT) domain
GPFHHGKB_01085 2.3e-113 yitU 3.1.3.104 S hydrolase
GPFHHGKB_01086 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
GPFHHGKB_01087 4.8e-81
GPFHHGKB_01088 5.3e-179 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
GPFHHGKB_01089 1.1e-41 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
GPFHHGKB_01090 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPFHHGKB_01091 7.1e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
GPFHHGKB_01092 5.1e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
GPFHHGKB_01093 8e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPFHHGKB_01094 4.2e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
GPFHHGKB_01095 1e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPFHHGKB_01096 1.7e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GPFHHGKB_01097 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GPFHHGKB_01098 1.1e-98 IQ reductase
GPFHHGKB_01099 5.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
GPFHHGKB_01100 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPFHHGKB_01101 1.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPFHHGKB_01102 4.2e-61 marR K Transcriptional regulator, MarR family
GPFHHGKB_01103 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPFHHGKB_01104 3e-36
GPFHHGKB_01106 7.4e-182 S Protein of unknown function DUF262
GPFHHGKB_01107 6.6e-193 pepV 3.5.1.18 E dipeptidase PepV
GPFHHGKB_01108 4.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPFHHGKB_01109 2.5e-63 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPFHHGKB_01110 6.4e-187 ytgP S Polysaccharide biosynthesis protein
GPFHHGKB_01111 2.4e-192 cycA E Amino acid permease
GPFHHGKB_01112 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPFHHGKB_01113 2.1e-176 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPFHHGKB_01115 1.9e-45 S VIT family
GPFHHGKB_01116 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
GPFHHGKB_01117 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPFHHGKB_01118 1.6e-112 rssA S Phospholipase, patatin family
GPFHHGKB_01119 8.2e-16
GPFHHGKB_01121 5.7e-39
GPFHHGKB_01122 2.5e-196 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
GPFHHGKB_01126 1.3e-86 S Fic/DOC family
GPFHHGKB_01127 6.6e-11 S sequence-specific DNA binding
GPFHHGKB_01128 2.3e-11 3.4.21.88 K Peptidase S24-like
GPFHHGKB_01139 7.6e-21 S Replication initiator protein A (RepA) N-terminus
GPFHHGKB_01144 2.7e-07
GPFHHGKB_01147 9.8e-20
GPFHHGKB_01148 1.3e-12 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
GPFHHGKB_01151 6e-25 3.4.22.70 M Sortase family
GPFHHGKB_01152 1.1e-88 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
GPFHHGKB_01153 8.1e-27 3.4.22.70 M Sortase family
GPFHHGKB_01154 2.2e-07 M PFAM Cna B domain protein
GPFHHGKB_01155 3.9e-21 S by MetaGeneAnnotator
GPFHHGKB_01165 6.9e-18 D nuclear chromosome segregation
GPFHHGKB_01167 1e-63 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
GPFHHGKB_01168 1.3e-154 2.1.1.72 V N-6 DNA Methylase
GPFHHGKB_01169 1.4e-30 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
GPFHHGKB_01170 1.5e-07
GPFHHGKB_01171 2.5e-56 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
GPFHHGKB_01175 1.6e-22 S PIN domain
GPFHHGKB_01176 3.6e-117 O AAA domain (Cdc48 subfamily)
GPFHHGKB_01177 2.3e-65
GPFHHGKB_01178 1.5e-83 3.1.21.3 V PFAM restriction modification system DNA specificity domain
GPFHHGKB_01179 6.3e-223 hsdM 2.1.1.72 V type I restriction-modification system
GPFHHGKB_01180 7.2e-283 hsdR 3.1.21.3 L DEAD/DEAH box helicase
GPFHHGKB_01181 5.8e-07
GPFHHGKB_01182 1.1e-45 yjaB_1 K Acetyltransferase (GNAT) domain
GPFHHGKB_01183 8.3e-82 yitS S EDD domain protein, DegV family
GPFHHGKB_01184 4.7e-56 racA K Domain of unknown function (DUF1836)
GPFHHGKB_01185 1.8e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPFHHGKB_01186 2.7e-84 potE2 E amino acid
GPFHHGKB_01188 2e-24
GPFHHGKB_01189 5.6e-146 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
GPFHHGKB_01190 4.9e-69
GPFHHGKB_01191 1.4e-81 S Protein of unknown function (DUF4238)
GPFHHGKB_01193 3.9e-60 hsdM 2.1.1.72 V type I restriction-modification system
GPFHHGKB_01194 2.2e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
GPFHHGKB_01196 2.2e-204 G PTS system Galactitol-specific IIC component
GPFHHGKB_01197 2e-93 M Exporter of polyketide antibiotics
GPFHHGKB_01198 9.5e-48 M Exporter of polyketide antibiotics
GPFHHGKB_01199 8.9e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
GPFHHGKB_01200 5.4e-44 S Repeat protein
GPFHHGKB_01201 2.8e-279 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GPFHHGKB_01202 3.4e-115 L Belongs to the 'phage' integrase family
GPFHHGKB_01203 7.9e-14
GPFHHGKB_01205 1.3e-26 ligA 2.7.7.7, 6.5.1.2 L EXOIII
GPFHHGKB_01206 1.5e-13
GPFHHGKB_01207 3.2e-16 L nuclease
GPFHHGKB_01208 1e-27 S Short C-terminal domain
GPFHHGKB_01210 3.8e-38 E Zn peptidase
GPFHHGKB_01211 4.1e-37 K Helix-turn-helix XRE-family like proteins
GPFHHGKB_01212 5.9e-10 XK27_07105 K Helix-turn-helix XRE-family like proteins
GPFHHGKB_01213 8.2e-19 S Domain of unknown function (DUF771)
GPFHHGKB_01218 3.6e-54 S Putative HNHc nuclease
GPFHHGKB_01219 4e-32 L N-terminal phage replisome organiser (Phage_rep_org_N)
GPFHHGKB_01222 1.6e-25
GPFHHGKB_01223 9.7e-71
GPFHHGKB_01226 2.2e-36 L recombinase activity
GPFHHGKB_01237 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPFHHGKB_01238 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GPFHHGKB_01239 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPFHHGKB_01240 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
GPFHHGKB_01241 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPFHHGKB_01242 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPFHHGKB_01243 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GPFHHGKB_01244 1.6e-55 ctsR K Belongs to the CtsR family
GPFHHGKB_01246 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GPFHHGKB_01247 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GPFHHGKB_01248 6.3e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GPFHHGKB_01249 7.2e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GPFHHGKB_01250 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GPFHHGKB_01260 2.2e-90 rfbP M Bacterial sugar transferase
GPFHHGKB_01261 2.4e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GPFHHGKB_01262 2.7e-111 ywqE 3.1.3.48 GM PHP domain protein
GPFHHGKB_01263 9.3e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
GPFHHGKB_01264 6.2e-71 epsB M biosynthesis protein
GPFHHGKB_01265 1.2e-23 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
GPFHHGKB_01266 3.3e-101
GPFHHGKB_01267 4.4e-89 2.4.1.342 GT4 M Glycosyl transferases group 1
GPFHHGKB_01268 3.2e-94 M Glycosyl transferases group 1
GPFHHGKB_01270 5.1e-65 wcmJ M Glycosyltransferase sugar-binding region containing DXD motif
GPFHHGKB_01271 9.7e-80 M Glycosyltransferase, group 2 family protein
GPFHHGKB_01272 6.5e-116 cps2J S Polysaccharide biosynthesis protein
GPFHHGKB_01273 2.7e-27 epsH S Hexapeptide repeat of succinyl-transferase
GPFHHGKB_01274 1.6e-106 M PFAM Glycosyl transferase, group 1
GPFHHGKB_01278 5.8e-80 S response to antibiotic
GPFHHGKB_01279 2.3e-15 S zinc-ribbon domain
GPFHHGKB_01280 1.8e-116 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
GPFHHGKB_01281 2.2e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GPFHHGKB_01282 7.3e-132 coaA 2.7.1.33 F Pantothenic acid kinase
GPFHHGKB_01283 1.9e-43 E GDSL-like Lipase/Acylhydrolase
GPFHHGKB_01284 1.6e-10 sdrF M domain protein
GPFHHGKB_01285 2.1e-102 L Belongs to the 'phage' integrase family
GPFHHGKB_01286 6.3e-20 infB M YSIRK type signal peptide
GPFHHGKB_01289 2.5e-21 ftsK D FtsK SpoIIIE family protein
GPFHHGKB_01292 1.7e-31 lytE M Lysin motif
GPFHHGKB_01294 2.8e-17
GPFHHGKB_01297 5.1e-65 floL S SPFH domain / Band 7 family
GPFHHGKB_01300 6e-66 S RRXRR protein
GPFHHGKB_01303 3.7e-123 dnaB 3.6.4.12 L DnaB-like helicase C terminal domain
GPFHHGKB_01304 6.2e-33 ybl78 L Conserved phage C-terminus (Phg_2220_C)
GPFHHGKB_01305 6.4e-69 soj D CobQ CobB MinD ParA nucleotide binding domain protein
GPFHHGKB_01307 1.2e-40 L Helix-turn-helix domain
GPFHHGKB_01308 2.5e-48 3.1.21.3 L N-6 DNA Methylase
GPFHHGKB_01309 8.4e-87 3.1.21.3 V N-6 DNA Methylase
GPFHHGKB_01310 2.3e-14 3.1.21.3 V N-6 DNA Methylase
GPFHHGKB_01313 9.9e-32 S RRXRR protein
GPFHHGKB_01316 7.2e-18 gepA S Protein of unknown function (DUF4065)
GPFHHGKB_01317 3.1e-13
GPFHHGKB_01318 7.9e-29 S Replication initiator protein A (RepA) N-terminus
GPFHHGKB_01321 4.9e-194 tnpB L Putative transposase DNA-binding domain
GPFHHGKB_01324 2.1e-64 NU StbA protein
GPFHHGKB_01327 3.4e-15
GPFHHGKB_01328 1.2e-102 res L helicase
GPFHHGKB_01329 1.5e-15
GPFHHGKB_01330 4.9e-38 srtA 3.4.22.70 M Sortase family
GPFHHGKB_01334 5.9e-47 clpC O ATPase family associated with various cellular activities (AAA)
GPFHHGKB_01337 4.6e-182 L Probable transposase
GPFHHGKB_01338 3e-38 S Sulfite exporter TauE/SafE
GPFHHGKB_01339 1.8e-70 K Sugar-specific transcriptional regulator TrmB
GPFHHGKB_01340 4.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GPFHHGKB_01341 2.3e-181 pepS E Thermophilic metalloprotease (M29)
GPFHHGKB_01342 3.8e-08 E Amino acid permease
GPFHHGKB_01343 1.5e-243 E Amino acid permease
GPFHHGKB_01344 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
GPFHHGKB_01345 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
GPFHHGKB_01346 5.9e-79 galM 5.1.3.3 G Aldose 1-epimerase
GPFHHGKB_01347 4.3e-213 malT G Transporter, major facilitator family protein
GPFHHGKB_01348 9.4e-101 malR K Transcriptional regulator, LacI family
GPFHHGKB_01349 1e-279 kup P Transport of potassium into the cell
GPFHHGKB_01351 2e-20 S Domain of unknown function (DUF3284)
GPFHHGKB_01352 2e-159 yfmL L DEAD DEAH box helicase
GPFHHGKB_01353 7e-128 mocA S Oxidoreductase
GPFHHGKB_01354 3.4e-24 S Domain of unknown function (DUF4828)
GPFHHGKB_01355 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
GPFHHGKB_01356 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GPFHHGKB_01357 9.4e-195 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
GPFHHGKB_01358 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
GPFHHGKB_01359 2.6e-163 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPFHHGKB_01360 2.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPFHHGKB_01361 9.4e-221 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
GPFHHGKB_01362 1.1e-41 O ADP-ribosylglycohydrolase
GPFHHGKB_01363 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
GPFHHGKB_01364 7.6e-210 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
GPFHHGKB_01365 2.8e-34 K GNAT family
GPFHHGKB_01366 1.7e-40
GPFHHGKB_01368 1.4e-45 yqhL P Rhodanese-like protein
GPFHHGKB_01369 4.7e-158 glk 2.7.1.2 G Glucokinase
GPFHHGKB_01370 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
GPFHHGKB_01371 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
GPFHHGKB_01372 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPFHHGKB_01373 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GPFHHGKB_01374 1.8e-19 D nuclear chromosome segregation
GPFHHGKB_01375 2.9e-76 yciQ P membrane protein (DUF2207)
GPFHHGKB_01376 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
GPFHHGKB_01377 2.8e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
GPFHHGKB_01378 2.9e-26 yneF S UPF0154 protein
GPFHHGKB_01379 2.2e-30 ynzC S UPF0291 protein
GPFHHGKB_01380 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPFHHGKB_01381 9.3e-178 recN L May be involved in recombinational repair of damaged DNA
GPFHHGKB_01382 1.1e-48 argR K Regulates arginine biosynthesis genes
GPFHHGKB_01383 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GPFHHGKB_01384 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPFHHGKB_01385 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPFHHGKB_01386 6.8e-147 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPFHHGKB_01387 1e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPFHHGKB_01388 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPFHHGKB_01389 3.7e-46 yqhY S Asp23 family, cell envelope-related function
GPFHHGKB_01390 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPFHHGKB_01391 1.3e-41 dut S dUTPase
GPFHHGKB_01392 5.5e-117
GPFHHGKB_01393 7.3e-105
GPFHHGKB_01394 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
GPFHHGKB_01395 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GPFHHGKB_01396 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPFHHGKB_01397 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
GPFHHGKB_01398 1.2e-88 nanK GK ROK family
GPFHHGKB_01399 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
GPFHHGKB_01400 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GPFHHGKB_01401 5.6e-75 K Helix-turn-helix domain, rpiR family
GPFHHGKB_01402 5.7e-56 yphA GM NAD dependent epimerase/dehydratase family
GPFHHGKB_01403 2e-216 yjeM E Amino Acid
GPFHHGKB_01405 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPFHHGKB_01406 2.4e-166 tetP J elongation factor G
GPFHHGKB_01407 2e-44 tetP J elongation factor G
GPFHHGKB_01408 1.8e-276 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPFHHGKB_01409 4.7e-35 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPFHHGKB_01410 2.2e-41 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPFHHGKB_01411 1.1e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
GPFHHGKB_01412 9.5e-120 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
GPFHHGKB_01413 1.4e-181 gatC G PTS system sugar-specific permease component
GPFHHGKB_01414 9.2e-36 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
GPFHHGKB_01415 2.7e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GPFHHGKB_01416 2.2e-60 K DeoR C terminal sensor domain
GPFHHGKB_01417 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GPFHHGKB_01419 4.3e-61 uspA T universal stress protein
GPFHHGKB_01421 2e-208 yfnA E Amino Acid
GPFHHGKB_01422 6.9e-117 lutA C Cysteine-rich domain
GPFHHGKB_01423 1.6e-245 lutB C 4Fe-4S dicluster domain
GPFHHGKB_01424 2.5e-66 yrjD S LUD domain
GPFHHGKB_01425 2.7e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPFHHGKB_01426 7.5e-13
GPFHHGKB_01427 9.4e-122 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
GPFHHGKB_01428 1e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GPFHHGKB_01429 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPFHHGKB_01430 2.1e-36 yrzL S Belongs to the UPF0297 family
GPFHHGKB_01431 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPFHHGKB_01432 1.9e-33 yrzB S Belongs to the UPF0473 family
GPFHHGKB_01433 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPFHHGKB_01434 1.4e-16 cvpA S Colicin V production protein
GPFHHGKB_01435 3.3e-311 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPFHHGKB_01436 9.9e-41 trxA O Belongs to the thioredoxin family
GPFHHGKB_01437 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPFHHGKB_01438 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GPFHHGKB_01439 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
GPFHHGKB_01440 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPFHHGKB_01441 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPFHHGKB_01442 7.1e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPFHHGKB_01443 9e-20 yaaA S S4 domain protein YaaA
GPFHHGKB_01444 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GPFHHGKB_01445 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPFHHGKB_01446 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GPFHHGKB_01447 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GPFHHGKB_01448 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPFHHGKB_01449 1.1e-199 nupG F Nucleoside
GPFHHGKB_01450 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
GPFHHGKB_01451 1.7e-53 K LysR substrate binding domain
GPFHHGKB_01452 1.8e-07
GPFHHGKB_01453 6e-66 yxkH G Polysaccharide deacetylase
GPFHHGKB_01454 9e-30 yqkB S Belongs to the HesB IscA family
GPFHHGKB_01456 5.8e-79 copY K Penicillinase repressor
GPFHHGKB_01457 0.0 3.6.3.4 P haloacid dehalogenase-like hydrolase
GPFHHGKB_01458 2.4e-40 S membrane protein (DUF2078)
GPFHHGKB_01459 4.8e-16 3.2.1.23 S Domain of unknown function DUF302
GPFHHGKB_01460 1.5e-33 3.2.1.23 S Domain of unknown function DUF302
GPFHHGKB_01461 5e-117 K response regulator
GPFHHGKB_01462 8.5e-230 baeS 2.7.13.3 T Histidine kinase
GPFHHGKB_01463 1.8e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPFHHGKB_01464 1.4e-67 spx4 1.20.4.1 P ArsC family
GPFHHGKB_01465 6e-34 L Helix-turn-helix domain
GPFHHGKB_01468 3.5e-98 cadD P Cadmium resistance transporter
GPFHHGKB_01471 5.3e-263 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GPFHHGKB_01472 4.9e-179 proV E ABC transporter, ATP-binding protein
GPFHHGKB_01473 6.8e-73 gshR 1.8.1.7 C Glutathione reductase
GPFHHGKB_01475 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPFHHGKB_01476 1.9e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GPFHHGKB_01477 7.8e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPFHHGKB_01478 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPFHHGKB_01479 2.8e-79 dnaB L replication initiation and membrane attachment
GPFHHGKB_01480 9.7e-108 dnaI L Primosomal protein DnaI
GPFHHGKB_01481 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPFHHGKB_01482 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPFHHGKB_01483 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GPFHHGKB_01484 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPFHHGKB_01485 2.5e-71 yqeG S HAD phosphatase, family IIIA
GPFHHGKB_01486 3e-180 yqeH S Ribosome biogenesis GTPase YqeH
GPFHHGKB_01487 1e-29 yhbY J RNA-binding protein
GPFHHGKB_01488 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPFHHGKB_01489 4.7e-71 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
GPFHHGKB_01490 5.1e-49 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GPFHHGKB_01491 5.5e-82 H Nodulation protein S (NodS)
GPFHHGKB_01492 1.3e-122 ylbM S Belongs to the UPF0348 family
GPFHHGKB_01493 3.5e-57 yceD S Uncharacterized ACR, COG1399
GPFHHGKB_01494 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GPFHHGKB_01498 3.7e-59 ruvB 3.6.4.12 L four-way junction helicase activity
GPFHHGKB_01499 8e-40 gepA S Protein of unknown function (DUF4065)
GPFHHGKB_01500 4.6e-43
GPFHHGKB_01501 3.3e-12 chpR T PFAM SpoVT AbrB
GPFHHGKB_01502 3.4e-29 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
GPFHHGKB_01503 1.7e-78 S Fic/DOC family
GPFHHGKB_01505 1.3e-25 D nuclear chromosome segregation
GPFHHGKB_01506 2e-08
GPFHHGKB_01507 1.2e-105 L Belongs to the 'phage' integrase family
GPFHHGKB_01508 3.8e-13 infB M YSIRK type signal peptide
GPFHHGKB_01510 1.6e-159 mgtE P Acts as a magnesium transporter
GPFHHGKB_01511 8.4e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
GPFHHGKB_01512 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPFHHGKB_01513 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
GPFHHGKB_01514 8.1e-256 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
GPFHHGKB_01515 3.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
GPFHHGKB_01516 1.7e-193 pbuX F xanthine permease
GPFHHGKB_01517 3.3e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GPFHHGKB_01518 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
GPFHHGKB_01519 3.2e-64 S ECF transporter, substrate-specific component
GPFHHGKB_01520 3.9e-128 mleP S Sodium Bile acid symporter family
GPFHHGKB_01521 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
GPFHHGKB_01522 6.2e-72 mleR K LysR family
GPFHHGKB_01523 1.1e-56 K transcriptional
GPFHHGKB_01524 7.6e-41 K Bacterial regulatory proteins, tetR family
GPFHHGKB_01525 6.1e-60 T Belongs to the universal stress protein A family
GPFHHGKB_01526 1.2e-44 K Copper transport repressor CopY TcrY
GPFHHGKB_01528 4e-89 plsC 2.3.1.51 I Acyltransferase
GPFHHGKB_01529 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
GPFHHGKB_01530 1.5e-27 yazA L GIY-YIG catalytic domain protein
GPFHHGKB_01531 7.2e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
GPFHHGKB_01532 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPFHHGKB_01533 7.4e-81 sip L Belongs to the 'phage' integrase family
GPFHHGKB_01534 1.9e-20
GPFHHGKB_01535 8e-14 S Pfam:DUF955
GPFHHGKB_01536 3e-19 K Helix-turn-helix domain
GPFHHGKB_01539 1.5e-117 K Phage regulatory protein
GPFHHGKB_01542 2.3e-18
GPFHHGKB_01543 5.8e-30 S Uncharacterized protein conserved in bacteria (DUF2188)
GPFHHGKB_01544 1.4e-14 K Cro/C1-type HTH DNA-binding domain
GPFHHGKB_01548 2e-77 S Siphovirus Gp157
GPFHHGKB_01549 1.8e-240 res L Helicase C-terminal domain protein
GPFHHGKB_01550 1.6e-116 L AAA domain
GPFHHGKB_01551 6.9e-84
GPFHHGKB_01552 2.8e-140 S Bifunctional DNA primase/polymerase, N-terminal
GPFHHGKB_01553 3e-229 S Virulence-associated protein E
GPFHHGKB_01554 1.2e-49 S VRR_NUC
GPFHHGKB_01557 3.1e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
GPFHHGKB_01558 5.7e-14 ybaN S Protein of unknown function (DUF454)
GPFHHGKB_01559 1.1e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GPFHHGKB_01560 2.7e-199 frdC 1.3.5.4 C FAD binding domain
GPFHHGKB_01561 1.5e-205 yflS P Sodium:sulfate symporter transmembrane region
GPFHHGKB_01562 3.2e-37 yncA 2.3.1.79 S Maltose acetyltransferase
GPFHHGKB_01563 7.9e-163 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPFHHGKB_01564 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
GPFHHGKB_01565 2.2e-96 ypuA S Protein of unknown function (DUF1002)
GPFHHGKB_01566 1.3e-148 3.2.1.18 GH33 M Rib/alpha-like repeat
GPFHHGKB_01567 8.2e-07 fhaB M Rib/alpha-like repeat
GPFHHGKB_01568 4.7e-71 S RRXRR protein
GPFHHGKB_01571 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
GPFHHGKB_01572 1e-27 ysxB J Cysteine protease Prp
GPFHHGKB_01573 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GPFHHGKB_01574 3.7e-12
GPFHHGKB_01576 2e-70
GPFHHGKB_01577 3.1e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
GPFHHGKB_01578 2.5e-177 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
GPFHHGKB_01579 7.9e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
GPFHHGKB_01580 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPFHHGKB_01581 2.9e-217 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPFHHGKB_01582 3.5e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPFHHGKB_01583 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GPFHHGKB_01584 3.2e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GPFHHGKB_01585 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPFHHGKB_01586 3.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GPFHHGKB_01587 4.1e-51 yeaL S Protein of unknown function (DUF441)
GPFHHGKB_01588 4.8e-125 cvfB S S1 domain
GPFHHGKB_01589 3.6e-112 xerD D recombinase XerD
GPFHHGKB_01590 8.4e-294 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GPFHHGKB_01591 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPFHHGKB_01592 3.7e-188 nhaC C Na H antiporter NhaC
GPFHHGKB_01593 3.9e-64 ypsA S Belongs to the UPF0398 family
GPFHHGKB_01594 1.9e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
GPFHHGKB_01595 7.6e-09 D Antitoxin component of a toxin-antitoxin (TA) module
GPFHHGKB_01596 2.3e-08 XK27_10540 S ParE toxin of type II toxin-antitoxin system, parDE
GPFHHGKB_01598 3.3e-94 dam 2.1.1.72 L Site-specific DNA-methyltransferase (Adenine-specific)
GPFHHGKB_01599 4.9e-128 3.1.21.4 L Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1
GPFHHGKB_01601 6.3e-302
GPFHHGKB_01602 1.3e-14
GPFHHGKB_01603 1.4e-16 S Bacterial toxin of type II toxin-antitoxin system, YafQ
GPFHHGKB_01604 5.6e-41
GPFHHGKB_01605 1.1e-10
GPFHHGKB_01610 9.7e-74 2.3.1.178 M GNAT acetyltransferase
GPFHHGKB_01611 1.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
GPFHHGKB_01612 3.7e-56 3.6.1.27 I Acid phosphatase homologues
GPFHHGKB_01613 2.3e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
GPFHHGKB_01615 4.4e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPFHHGKB_01616 7.6e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
GPFHHGKB_01617 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GPFHHGKB_01618 2.5e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GPFHHGKB_01619 5.8e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GPFHHGKB_01620 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GPFHHGKB_01622 4.2e-92 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPFHHGKB_01623 4.8e-44
GPFHHGKB_01624 1.2e-119 ica2 GT2 M Glycosyl transferase family group 2
GPFHHGKB_01625 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
GPFHHGKB_01626 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
GPFHHGKB_01627 1.6e-58 ypbB 5.1.3.1 S Helix-turn-helix domain
GPFHHGKB_01628 9.1e-129 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
GPFHHGKB_01629 7.7e-12 M Lysin motif
GPFHHGKB_01630 2.6e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GPFHHGKB_01631 1.3e-82 lytH 3.5.1.28 M Ami_3
GPFHHGKB_01632 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
GPFHHGKB_01633 2.3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPFHHGKB_01634 4.7e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GPFHHGKB_01635 1.3e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPFHHGKB_01636 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
GPFHHGKB_01637 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
GPFHHGKB_01638 8.4e-218 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPFHHGKB_01639 5.9e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
GPFHHGKB_01640 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPFHHGKB_01641 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GPFHHGKB_01642 3.7e-59 arsC 1.20.4.1 T Low molecular weight phosphatase family
GPFHHGKB_01643 1.6e-171 rpsA 1.17.7.4 J Ribosomal protein S1
GPFHHGKB_01644 3.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GPFHHGKB_01645 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPFHHGKB_01647 1.5e-21 K Acetyltransferase (GNAT) domain
GPFHHGKB_01648 9.6e-113 natA S Domain of unknown function (DUF4162)
GPFHHGKB_01649 4.2e-79 natB CP ABC-type Na efflux pump, permease component
GPFHHGKB_01650 1.8e-95 EG EamA-like transporter family
GPFHHGKB_01651 4.1e-81 yjjH S Calcineurin-like phosphoesterase
GPFHHGKB_01652 5.7e-188 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPFHHGKB_01653 2.4e-40 6.3.3.2 S ASCH
GPFHHGKB_01654 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
GPFHHGKB_01655 1.8e-116 degV S EDD domain protein, DegV family
GPFHHGKB_01656 1.3e-70 S Uncharacterised protein family (UPF0236)
GPFHHGKB_01657 1.5e-25 S Uncharacterised protein family (UPF0236)
GPFHHGKB_01660 2.6e-60 M Peptidase family M23
GPFHHGKB_01662 3.8e-239 trsE S COG0433 Predicted ATPase
GPFHHGKB_01663 4.3e-40
GPFHHGKB_01664 6.6e-08 S Uncharacterized protein pXO2-11
GPFHHGKB_01666 5.6e-133 NU StbA protein
GPFHHGKB_01667 1.5e-86 endA F DNA RNA non-specific endonuclease
GPFHHGKB_01668 1.9e-21 ssb L Single-stranded DNA-binding protein
GPFHHGKB_01681 4.4e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GPFHHGKB_01684 1.5e-27 arpU S Phage transcriptional regulator, ArpU family
GPFHHGKB_01687 1.6e-21
GPFHHGKB_01688 9.5e-89 L HNH nucleases
GPFHHGKB_01689 4.3e-83 L Phage terminase, small subunit
GPFHHGKB_01690 0.0 S Phage Terminase
GPFHHGKB_01692 4.7e-208 S Phage portal protein
GPFHHGKB_01693 1.2e-118 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
GPFHHGKB_01694 1.2e-222 S Phage capsid family
GPFHHGKB_01695 4.8e-22 S Phage gp6-like head-tail connector protein
GPFHHGKB_01696 2.9e-60 S Phage head-tail joining protein
GPFHHGKB_01697 1.1e-65 S Bacteriophage HK97-gp10, putative tail-component
GPFHHGKB_01698 2.7e-64 S Protein of unknown function (DUF806)
GPFHHGKB_01699 5.5e-124 S Phage tail tube protein
GPFHHGKB_01700 6.3e-54 S Phage tail assembly chaperone proteins, TAC
GPFHHGKB_01703 6.4e-26 S Phage Mu protein F like protein
GPFHHGKB_01705 2.7e-20 S Phage minor structural protein GP20
GPFHHGKB_01706 2.5e-97 S T=7 icosahedral viral capsid
GPFHHGKB_01707 5.2e-15
GPFHHGKB_01708 6.7e-30 S Minor capsid protein
GPFHHGKB_01709 7.9e-16 S Minor capsid protein
GPFHHGKB_01710 7.6e-17 S Minor capsid protein from bacteriophage
GPFHHGKB_01711 7.5e-38 N domain, Protein
GPFHHGKB_01713 6.3e-39 S Bacteriophage Gp15 protein
GPFHHGKB_01714 5e-106 M Phage tail tape measure protein TP901
GPFHHGKB_01715 1.3e-60 S Phage tail protein
GPFHHGKB_01716 2.4e-102 M Prophage endopeptidase tail
GPFHHGKB_01717 6.1e-103 V domain protein
GPFHHGKB_01718 4e-16
GPFHHGKB_01720 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPFHHGKB_01721 1.1e-172 malY 4.4.1.8 E Aminotransferase, class I
GPFHHGKB_01722 1.2e-117 K AI-2E family transporter
GPFHHGKB_01723 3.1e-61 EG EamA-like transporter family
GPFHHGKB_01724 3.9e-76 L haloacid dehalogenase-like hydrolase
GPFHHGKB_01725 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GPFHHGKB_01726 1.5e-62 1.5.1.38 S NADPH-dependent FMN reductase
GPFHHGKB_01727 7.3e-94 C Luciferase-like monooxygenase
GPFHHGKB_01728 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPFHHGKB_01729 4.5e-129 mleP2 S Sodium Bile acid symporter family
GPFHHGKB_01730 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPFHHGKB_01732 3.6e-44 ydcK S Belongs to the SprT family
GPFHHGKB_01733 2.8e-251 yhgF K Tex-like protein N-terminal domain protein
GPFHHGKB_01734 1.4e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GPFHHGKB_01735 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPFHHGKB_01736 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GPFHHGKB_01737 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
GPFHHGKB_01738 4.6e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPFHHGKB_01740 1.1e-07
GPFHHGKB_01741 1.6e-197 dtpT U amino acid peptide transporter
GPFHHGKB_01743 4.2e-70 L Transposase
GPFHHGKB_01744 1.6e-79 L transposase and inactivated derivatives, IS30 family
GPFHHGKB_01745 5.3e-35 tra L Transposase and inactivated derivatives, IS30 family
GPFHHGKB_01746 1.1e-16 K Cro/C1-type HTH DNA-binding domain
GPFHHGKB_01749 2.9e-39 ebh D nuclear chromosome segregation
GPFHHGKB_01750 1.3e-135 L Transposase
GPFHHGKB_01751 1.6e-74 L Transposase
GPFHHGKB_01752 1.8e-21 L Transposase
GPFHHGKB_01755 4.8e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GPFHHGKB_01756 4.9e-10 L Resolvase, N terminal domain
GPFHHGKB_01758 1.7e-78 L Resolvase, N terminal domain
GPFHHGKB_01759 8.8e-53 L Protein involved in initiation of plasmid replication
GPFHHGKB_01760 5.3e-18
GPFHHGKB_01763 4e-48 L Resolvase, N terminal domain
GPFHHGKB_01764 2.3e-53 S Bacterial protein of unknown function (DUF961)
GPFHHGKB_01765 1e-63 S Bacterial protein of unknown function (DUF961)
GPFHHGKB_01766 0.0 tetP J elongation factor G
GPFHHGKB_01767 1e-30
GPFHHGKB_01768 1.8e-32 ywiB S Domain of unknown function (DUF1934)
GPFHHGKB_01769 2.9e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GPFHHGKB_01770 1.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GPFHHGKB_01773 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPFHHGKB_01774 1.5e-188 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPFHHGKB_01775 1.4e-40 rpmE2 J Ribosomal protein L31
GPFHHGKB_01776 2.2e-61
GPFHHGKB_01777 2.2e-249 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
GPFHHGKB_01778 1.8e-208 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GPFHHGKB_01779 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPFHHGKB_01782 1.6e-151 V Pfam:Methyltransf_26
GPFHHGKB_01783 3.4e-225 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GPFHHGKB_01784 4.7e-153 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GPFHHGKB_01785 2.9e-25 L Transposase domain (DUF772)
GPFHHGKB_01786 1e-33 S Enterocin A Immunity
GPFHHGKB_01787 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
GPFHHGKB_01788 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
GPFHHGKB_01789 6.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
GPFHHGKB_01790 1.6e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPFHHGKB_01791 8.2e-154 yacL S domain protein
GPFHHGKB_01792 4.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPFHHGKB_01793 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPFHHGKB_01794 4.9e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GPFHHGKB_01795 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPFHHGKB_01796 1.3e-64 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
GPFHHGKB_01797 1.8e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
GPFHHGKB_01798 1.2e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
GPFHHGKB_01799 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
GPFHHGKB_01800 4.5e-43 gutM K Glucitol operon activator protein (GutM)
GPFHHGKB_01801 2.2e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
GPFHHGKB_01802 4e-110 IQ NAD dependent epimerase/dehydratase family
GPFHHGKB_01803 2.1e-49 M Phage tail tape measure protein TP901
GPFHHGKB_01805 4.3e-07
GPFHHGKB_01810 1.1e-08 S Phage minor capsid protein 2
GPFHHGKB_01811 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
GPFHHGKB_01812 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
GPFHHGKB_01813 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPFHHGKB_01814 2.3e-219 cydD CO ABC transporter transmembrane region
GPFHHGKB_01815 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GPFHHGKB_01816 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
GPFHHGKB_01817 2.1e-194 cydA 1.10.3.14 C ubiquinol oxidase
GPFHHGKB_01818 3.1e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
GPFHHGKB_01819 3.7e-28 xlyB 3.5.1.28 CBM50 M LysM domain
GPFHHGKB_01820 2.3e-19 glpE P Rhodanese Homology Domain
GPFHHGKB_01821 2.1e-48 lytE M LysM domain protein
GPFHHGKB_01822 6.9e-92 T Calcineurin-like phosphoesterase superfamily domain
GPFHHGKB_01823 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
GPFHHGKB_01825 8.2e-73 draG O ADP-ribosylglycohydrolase
GPFHHGKB_01826 5.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPFHHGKB_01827 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPFHHGKB_01828 5.1e-62 divIVA D DivIVA domain protein
GPFHHGKB_01829 3.5e-82 ylmH S S4 domain protein
GPFHHGKB_01830 3e-19 yggT S YGGT family
GPFHHGKB_01831 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GPFHHGKB_01832 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPFHHGKB_01833 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GPFHHGKB_01834 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GPFHHGKB_01835 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPFHHGKB_01836 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPFHHGKB_01837 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPFHHGKB_01838 8.4e-280 ftsI 3.4.16.4 M Penicillin-binding Protein
GPFHHGKB_01839 2.5e-11 ftsL D cell division protein FtsL
GPFHHGKB_01840 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GPFHHGKB_01841 5.2e-64 mraZ K Belongs to the MraZ family
GPFHHGKB_01843 1.6e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
GPFHHGKB_01844 3.1e-98 D Alpha beta
GPFHHGKB_01845 1.8e-108 aatB ET ABC transporter substrate-binding protein
GPFHHGKB_01846 1.4e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GPFHHGKB_01847 1.9e-94 glnP P ABC transporter permease
GPFHHGKB_01848 1.8e-126 minD D Belongs to the ParA family
GPFHHGKB_01849 1.4e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GPFHHGKB_01850 3.4e-54 mreD M rod shape-determining protein MreD
GPFHHGKB_01851 2.1e-88 mreC M Involved in formation and maintenance of cell shape
GPFHHGKB_01852 1.8e-155 mreB D cell shape determining protein MreB
GPFHHGKB_01853 4.5e-21 K Cold shock
GPFHHGKB_01854 6.2e-80 radC L DNA repair protein
GPFHHGKB_01855 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GPFHHGKB_01856 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GPFHHGKB_01857 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPFHHGKB_01858 9.9e-163 iscS2 2.8.1.7 E Aminotransferase class V
GPFHHGKB_01859 1.2e-172 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GPFHHGKB_01860 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
GPFHHGKB_01861 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPFHHGKB_01862 5.9e-24 yueI S Protein of unknown function (DUF1694)
GPFHHGKB_01863 3.4e-188 rarA L recombination factor protein RarA
GPFHHGKB_01865 3.2e-73 usp6 T universal stress protein
GPFHHGKB_01866 8.1e-54 tag 3.2.2.20 L glycosylase
GPFHHGKB_01867 2.2e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GPFHHGKB_01868 5.9e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GPFHHGKB_01870 6.8e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
GPFHHGKB_01871 8.4e-298 S membrane
GPFHHGKB_01872 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPFHHGKB_01873 5.2e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
GPFHHGKB_01874 5.8e-101 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
GPFHHGKB_01875 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GPFHHGKB_01877 1.4e-16
GPFHHGKB_01878 1.8e-198 oatA I Acyltransferase
GPFHHGKB_01879 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPFHHGKB_01880 2.1e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GPFHHGKB_01881 5.8e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPFHHGKB_01884 1.8e-36 S Phosphoesterase
GPFHHGKB_01885 1.5e-72 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPFHHGKB_01886 1.1e-60 yslB S Protein of unknown function (DUF2507)
GPFHHGKB_01890 1.9e-08 2.3.1.19 K Cro/C1-type HTH DNA-binding domain
GPFHHGKB_01895 4.2e-40
GPFHHGKB_01896 5.7e-07 L Integrase core domain
GPFHHGKB_01898 2.1e-12 S Thioredoxin
GPFHHGKB_01900 2.3e-116 K Primase C terminal 1 (PriCT-1)
GPFHHGKB_01901 3.1e-40 K Transcriptional regulator
GPFHHGKB_01902 9.4e-202 FbpA K Fibronectin-binding protein
GPFHHGKB_01903 2.1e-19 M domain protein
GPFHHGKB_01904 3e-35 agrA KT Response regulator of the LytR AlgR family
GPFHHGKB_01905 1e-43 2.7.13.3 T protein histidine kinase activity
GPFHHGKB_01906 0.0 pepN 3.4.11.2 E aminopeptidase
GPFHHGKB_01907 1.1e-35
GPFHHGKB_01909 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
GPFHHGKB_01910 6.6e-63 licT K transcriptional antiterminator
GPFHHGKB_01911 1.4e-28 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GPFHHGKB_01912 3.6e-99 fabK 1.3.1.9 S Nitronate monooxygenase
GPFHHGKB_01913 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GPFHHGKB_01915 8.2e-266 fbp 3.1.3.11 G phosphatase activity
GPFHHGKB_01916 1.1e-70 xerD L Phage integrase, N-terminal SAM-like domain
GPFHHGKB_01918 2.2e-233 sufB O assembly protein SufB
GPFHHGKB_01919 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
GPFHHGKB_01920 2.4e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPFHHGKB_01921 2.3e-144 sufD O FeS assembly protein SufD
GPFHHGKB_01922 2.8e-116 sufC O FeS assembly ATPase SufC
GPFHHGKB_01923 1.3e-224 E ABC transporter, substratebinding protein
GPFHHGKB_01928 1.9e-49 L Probable transposase
GPFHHGKB_01929 1.2e-21 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
GPFHHGKB_01930 1.2e-78 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
GPFHHGKB_01931 0.0 S Bacterial membrane protein YfhO
GPFHHGKB_01932 5.1e-53 gtcA S Teichoic acid glycosylation protein
GPFHHGKB_01933 5.1e-54 fld C Flavodoxin
GPFHHGKB_01934 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
GPFHHGKB_01935 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GPFHHGKB_01936 5.2e-12 mltD CBM50 M Lysin motif
GPFHHGKB_01937 3.8e-93 yihY S Belongs to the UPF0761 family
GPFHHGKB_01938 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPFHHGKB_01939 0.0 O Belongs to the peptidase S8 family
GPFHHGKB_01940 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
GPFHHGKB_01941 9e-102 qmcA O prohibitin homologues
GPFHHGKB_01942 1.8e-11 S YjcQ protein
GPFHHGKB_01943 5.4e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
GPFHHGKB_01944 2.2e-83 dps P Ferritin-like domain
GPFHHGKB_01945 1.3e-49 K Cro/C1-type HTH DNA-binding domain
GPFHHGKB_01946 3.6e-15 Z012_01675 S X-Pro dipeptidyl-peptidase (S15 family)
GPFHHGKB_01947 6.6e-15 yjaB_1 K Psort location Cytoplasmic, score 8.87
GPFHHGKB_01950 7.9e-27 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GPFHHGKB_01951 6.7e-72 ywlG S Belongs to the UPF0340 family
GPFHHGKB_01952 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GPFHHGKB_01953 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPFHHGKB_01954 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GPFHHGKB_01956 3.2e-181 pbuG S permease
GPFHHGKB_01957 6.4e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
GPFHHGKB_01958 9e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GPFHHGKB_01959 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GPFHHGKB_01960 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GPFHHGKB_01961 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPFHHGKB_01962 5.4e-13
GPFHHGKB_01963 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
GPFHHGKB_01964 1.4e-64 G Xylose isomerase domain protein TIM barrel
GPFHHGKB_01965 6.6e-154 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GPFHHGKB_01966 1.1e-206 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPFHHGKB_01967 1.9e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
GPFHHGKB_01968 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GPFHHGKB_01969 7.7e-41 S Iron-sulfur cluster assembly protein
GPFHHGKB_01970 1.3e-66 S Protein of unknown function (DUF1440)
GPFHHGKB_01971 1e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
GPFHHGKB_01972 3.2e-188 mtnE 2.6.1.83 E Aminotransferase
GPFHHGKB_01973 6.9e-37
GPFHHGKB_01974 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GPFHHGKB_01975 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPFHHGKB_01976 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPFHHGKB_01977 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPFHHGKB_01978 1.7e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GPFHHGKB_01980 3.1e-111 K response regulator
GPFHHGKB_01981 1.3e-167 arlS 2.7.13.3 T Histidine kinase
GPFHHGKB_01982 3e-14 S Acyltransferase family
GPFHHGKB_01983 6.9e-68 sip L Belongs to the 'phage' integrase family
GPFHHGKB_01986 1.7e-07 K Helix-turn-helix XRE-family like proteins
GPFHHGKB_01989 2e-10 S Protein of unknown function (DUF805)
GPFHHGKB_01991 3e-89 S Acyltransferase family
GPFHHGKB_01992 6e-161 purD 6.3.4.13 F Belongs to the GARS family
GPFHHGKB_01993 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GPFHHGKB_01994 1.2e-74 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPFHHGKB_01995 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GPFHHGKB_01996 5.5e-227 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPFHHGKB_01997 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPFHHGKB_01998 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPFHHGKB_01999 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPFHHGKB_02000 2.9e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GPFHHGKB_02001 1.8e-131 ylbL T Belongs to the peptidase S16 family
GPFHHGKB_02002 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPFHHGKB_02003 1e-72 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
GPFHHGKB_02004 1.8e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
GPFHHGKB_02005 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GPFHHGKB_02006 3e-101 ftsW D Belongs to the SEDS family
GPFHHGKB_02007 3.3e-148 manN G system, mannose fructose sorbose family IID component
GPFHHGKB_02008 7e-115 manY G PTS system
GPFHHGKB_02009 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
GPFHHGKB_02010 0.0 typA T GTP-binding protein TypA
GPFHHGKB_02011 6.3e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
GPFHHGKB_02012 1.2e-24 yktA S Belongs to the UPF0223 family
GPFHHGKB_02013 2.6e-30 1.1.1.27 C L-malate dehydrogenase activity
GPFHHGKB_02014 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPFHHGKB_02015 9.5e-25
GPFHHGKB_02016 5e-23 ykzG S Belongs to the UPF0356 family
GPFHHGKB_02017 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPFHHGKB_02018 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPFHHGKB_02019 7.8e-198 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPFHHGKB_02020 7.8e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GPFHHGKB_02021 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPFHHGKB_02022 6.1e-19 S Tetratricopeptide repeat
GPFHHGKB_02023 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPFHHGKB_02024 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPFHHGKB_02025 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPFHHGKB_02026 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
GPFHHGKB_02027 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GPFHHGKB_02028 8.2e-199 yfnA E amino acid
GPFHHGKB_02029 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
GPFHHGKB_02030 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GPFHHGKB_02031 1.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPFHHGKB_02032 3.8e-27 ylqC S Belongs to the UPF0109 family
GPFHHGKB_02033 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GPFHHGKB_02034 5.5e-203 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPFHHGKB_02035 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GPFHHGKB_02036 7.2e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPFHHGKB_02037 1.3e-208 smc D Required for chromosome condensation and partitioning
GPFHHGKB_02038 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GPFHHGKB_02039 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPFHHGKB_02040 2.7e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GPFHHGKB_02041 4e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPFHHGKB_02042 4.8e-238 yloV S DAK2 domain fusion protein YloV
GPFHHGKB_02043 4.5e-53 asp S Asp23 family, cell envelope-related function
GPFHHGKB_02044 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GPFHHGKB_02045 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
GPFHHGKB_02046 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GPFHHGKB_02047 7.5e-191 KLT serine threonine protein kinase
GPFHHGKB_02048 3.3e-90 stp 3.1.3.16 T phosphatase
GPFHHGKB_02049 1.3e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPFHHGKB_02050 1.3e-139 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPFHHGKB_02051 4.6e-287 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPFHHGKB_02052 2.2e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPFHHGKB_02053 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GPFHHGKB_02054 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GPFHHGKB_02055 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
GPFHHGKB_02056 1e-102 L Transposase
GPFHHGKB_02057 1.1e-90 infB UW LPXTG-motif cell wall anchor domain protein
GPFHHGKB_02059 1.4e-06
GPFHHGKB_02060 8.8e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GPFHHGKB_02061 1.7e-54 rplI J Binds to the 23S rRNA
GPFHHGKB_02062 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GPFHHGKB_02063 4e-64 C FMN binding
GPFHHGKB_02064 2.8e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPFHHGKB_02065 1.1e-76 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
GPFHHGKB_02066 1.1e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
GPFHHGKB_02067 1e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
GPFHHGKB_02068 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPFHHGKB_02069 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
GPFHHGKB_02070 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GPFHHGKB_02071 5.3e-279 M Phage tail tape measure protein TP901
GPFHHGKB_02072 1.6e-138 S Phage tail protein
GPFHHGKB_02073 5.6e-272 rny D peptidase
GPFHHGKB_02074 5.1e-99 M Prophage endopeptidase tail
GPFHHGKB_02075 9.3e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
GPFHHGKB_02076 1.2e-135 pfoS S Phosphotransferase system, EIIC
GPFHHGKB_02077 1.1e-27 K Helix-turn-helix XRE-family like proteins
GPFHHGKB_02078 1.1e-118 repE K Primase C terminal 1 (PriCT-1)
GPFHHGKB_02082 2e-47 pts33BCA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Pts system
GPFHHGKB_02083 6.8e-169 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPFHHGKB_02084 1.6e-36 S Replication initiator protein A (RepA) N-terminus
GPFHHGKB_02085 9.4e-109 L Initiator Replication protein
GPFHHGKB_02089 1e-11 arpU S Phage transcriptional regulator, ArpU family
GPFHHGKB_02091 1.3e-31
GPFHHGKB_02092 3.4e-167 S Terminase RNAseH like domain
GPFHHGKB_02093 9.6e-145 S Phage portal protein, SPP1 Gp6-like
GPFHHGKB_02094 3.6e-116 S Glycosyl transferase family 2
GPFHHGKB_02095 7.4e-64 D peptidase
GPFHHGKB_02096 0.0 asnB 6.3.5.4 E Asparagine synthase
GPFHHGKB_02097 4.1e-15 ywzB S Protein of unknown function (DUF1146)
GPFHHGKB_02098 7.1e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPFHHGKB_02099 4.1e-165 mbl D Cell shape determining protein MreB Mrl
GPFHHGKB_02100 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
GPFHHGKB_02101 1.3e-13 S Protein of unknown function (DUF2969)
GPFHHGKB_02102 6.1e-187 rodA D Belongs to the SEDS family
GPFHHGKB_02103 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
GPFHHGKB_02106 2.6e-259 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GPFHHGKB_02107 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPFHHGKB_02108 1.6e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPFHHGKB_02109 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPFHHGKB_02110 2.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GPFHHGKB_02111 7.2e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GPFHHGKB_02112 1.1e-40 yabR J RNA binding
GPFHHGKB_02113 2.3e-18 divIC D Septum formation initiator
GPFHHGKB_02114 3.6e-31 yabO J S4 domain protein
GPFHHGKB_02115 7.3e-140 yabM S Polysaccharide biosynthesis protein
GPFHHGKB_02116 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPFHHGKB_02117 3.2e-74 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GPFHHGKB_02118 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GPFHHGKB_02119 5.5e-86 S (CBS) domain
GPFHHGKB_02120 8.1e-142 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPFHHGKB_02121 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPFHHGKB_02122 7.2e-53 perR P Belongs to the Fur family
GPFHHGKB_02123 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
GPFHHGKB_02124 8e-98 sbcC L Putative exonuclease SbcCD, C subunit
GPFHHGKB_02125 2.3e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GPFHHGKB_02126 7.6e-39 M LysM domain protein
GPFHHGKB_02127 1.5e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GPFHHGKB_02128 2.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GPFHHGKB_02129 3.9e-34 ygfC K Bacterial regulatory proteins, tetR family
GPFHHGKB_02130 8.2e-111 hrtB V ABC transporter permease
GPFHHGKB_02131 4e-87 devA 3.6.3.25 V ABC transporter, ATP-binding protein
GPFHHGKB_02133 6.6e-39 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GPFHHGKB_02134 0.0 helD 3.6.4.12 L DNA helicase
GPFHHGKB_02135 8.9e-246 yjbQ P TrkA C-terminal domain protein
GPFHHGKB_02136 3.4e-23
GPFHHGKB_02137 1.2e-59 rpsI J Belongs to the universal ribosomal protein uS9 family
GPFHHGKB_02138 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPFHHGKB_02139 1.2e-124 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GPFHHGKB_02140 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPFHHGKB_02141 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPFHHGKB_02142 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPFHHGKB_02143 4.8e-53 rplQ J Ribosomal protein L17
GPFHHGKB_02144 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPFHHGKB_02145 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPFHHGKB_02146 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPFHHGKB_02147 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GPFHHGKB_02148 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPFHHGKB_02149 7.6e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GPFHHGKB_02150 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GPFHHGKB_02151 1e-67 rplO J Binds to the 23S rRNA
GPFHHGKB_02152 2.1e-22 rpmD J Ribosomal protein L30
GPFHHGKB_02153 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPFHHGKB_02154 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPFHHGKB_02155 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPFHHGKB_02156 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPFHHGKB_02157 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPFHHGKB_02158 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPFHHGKB_02159 1.6e-46 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPFHHGKB_02160 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPFHHGKB_02161 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPFHHGKB_02162 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
GPFHHGKB_02163 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPFHHGKB_02164 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPFHHGKB_02165 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPFHHGKB_02166 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPFHHGKB_02167 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPFHHGKB_02168 3.8e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GPFHHGKB_02169 1e-100 rplD J Forms part of the polypeptide exit tunnel
GPFHHGKB_02170 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPFHHGKB_02171 3.7e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
GPFHHGKB_02172 6.8e-165 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPFHHGKB_02173 2.2e-79 K rpiR family
GPFHHGKB_02174 4.5e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GPFHHGKB_02175 5.5e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
GPFHHGKB_02176 3.8e-21 K Acetyltransferase (GNAT) domain
GPFHHGKB_02177 2.9e-182 steT E amino acid
GPFHHGKB_02178 6.9e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPFHHGKB_02179 9.7e-37 ptsH G phosphocarrier protein HPR
GPFHHGKB_02180 1.5e-15
GPFHHGKB_02181 0.0 clpE O Belongs to the ClpA ClpB family
GPFHHGKB_02182 6.7e-146 lmrP E Major Facilitator Superfamily
GPFHHGKB_02183 1.8e-169 T PhoQ Sensor
GPFHHGKB_02184 5e-104 K response regulator
GPFHHGKB_02185 5e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPFHHGKB_02189 2.6e-16 S RelB antitoxin
GPFHHGKB_02190 4.6e-37
GPFHHGKB_02194 9.9e-62 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GPFHHGKB_02198 2.1e-134 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylase
GPFHHGKB_02199 3.6e-16
GPFHHGKB_02200 2e-14 vatD S acetyltransferase'
GPFHHGKB_02201 9.3e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
GPFHHGKB_02202 6.2e-210 glnP P ABC transporter
GPFHHGKB_02207 1.2e-09
GPFHHGKB_02208 3.7e-26 radC L DNA repair protein
GPFHHGKB_02214 2.3e-25 L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPFHHGKB_02215 2e-57 S AAA domain, putative AbiEii toxin, Type IV TA system
GPFHHGKB_02216 5.6e-13 S RloB-like protein
GPFHHGKB_02217 2.1e-21
GPFHHGKB_02218 3.2e-12 N Bacterial Ig-like domain 2
GPFHHGKB_02223 2.7e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
GPFHHGKB_02224 8.7e-117 M Glycosyl hydrolases family 25
GPFHHGKB_02225 4.5e-70 pac DM Glucan-binding protein C
GPFHHGKB_02227 7.7e-69
GPFHHGKB_02228 5.7e-41 L Protein of unknown function (DUF3991)
GPFHHGKB_02229 9.9e-167 topA2 5.99.1.2 G Topoisomerase IA
GPFHHGKB_02232 2.2e-148 clpB O Belongs to the ClpA ClpB family
GPFHHGKB_02236 7.6e-220 U TraM recognition site of TraD and TraG
GPFHHGKB_02237 6e-77
GPFHHGKB_02239 3.5e-27
GPFHHGKB_02240 2.2e-191 U type IV secretory pathway VirB4
GPFHHGKB_02242 2.5e-29 M CHAP domain
GPFHHGKB_02245 9.1e-47 sip L Belongs to the 'phage' integrase family
GPFHHGKB_02246 1.9e-29
GPFHHGKB_02247 2.9e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GPFHHGKB_02248 3.5e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPFHHGKB_02249 4.7e-80 yvfR V ABC transporter
GPFHHGKB_02250 2.4e-53 yvfS V ABC-2 type transporter
GPFHHGKB_02251 5.4e-57 desK 2.7.13.3 T Histidine kinase
GPFHHGKB_02252 2.2e-76 desR K helix_turn_helix, Lux Regulon
GPFHHGKB_02253 1.6e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
GPFHHGKB_02254 1e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
GPFHHGKB_02258 1.1e-142 xerS L Phage integrase family
GPFHHGKB_02259 1.3e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GPFHHGKB_02260 1.9e-26 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPFHHGKB_02261 2.2e-50
GPFHHGKB_02263 3.2e-195 copB 3.6.3.4 P P-type ATPase
GPFHHGKB_02264 2e-142 copB 3.6.3.4 P P-type ATPase
GPFHHGKB_02265 1.9e-74 K Copper transport repressor CopY TcrY
GPFHHGKB_02266 1.9e-56 cadX K Bacterial regulatory protein, arsR family
GPFHHGKB_02267 1.1e-94 cadD P Cadmium resistance transporter
GPFHHGKB_02268 2.4e-25 K Helix-turn-helix domain
GPFHHGKB_02269 2.3e-33 S Phage derived protein Gp49-like (DUF891)
GPFHHGKB_02270 3.1e-33 L Resolvase, N terminal domain
GPFHHGKB_02271 1.9e-07 L Resolvase, N terminal domain
GPFHHGKB_02276 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
GPFHHGKB_02277 2.7e-30 P Heavy-metal-associated domain
GPFHHGKB_02279 2.3e-218 L Probable transposase
GPFHHGKB_02280 1.8e-61 yvdD 3.2.2.10 S Possible lysine decarboxylase
GPFHHGKB_02281 3.3e-15 S HicB family
GPFHHGKB_02282 7.5e-18 hicA S HicA toxin of bacterial toxin-antitoxin,
GPFHHGKB_02286 1.1e-159 L transposase, IS605 OrfB family
GPFHHGKB_02289 9.1e-31 L Helix-turn-helix domain
GPFHHGKB_02290 3.1e-87 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
GPFHHGKB_02291 1.7e-73 S peptidoglycan catabolic process
GPFHHGKB_02292 3.7e-37 yiiE S Protein of unknown function (DUF1211)
GPFHHGKB_02293 3.3e-12 yiiE S Protein of unknown function (DUF1211)
GPFHHGKB_02294 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GPFHHGKB_02295 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GPFHHGKB_02296 3.6e-17 yneR
GPFHHGKB_02297 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPFHHGKB_02298 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
GPFHHGKB_02299 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GPFHHGKB_02300 3.8e-152 mdtG EGP Major facilitator Superfamily
GPFHHGKB_02301 3.8e-14 yobS K transcriptional regulator
GPFHHGKB_02302 2.8e-109 glcU U sugar transport
GPFHHGKB_02303 4.4e-170 yjjP S Putative threonine/serine exporter
GPFHHGKB_02304 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
GPFHHGKB_02305 2.2e-96 yicL EG EamA-like transporter family
GPFHHGKB_02306 1.8e-222 pepF E Oligopeptidase F
GPFHHGKB_02307 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPFHHGKB_02308 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GPFHHGKB_02309 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
GPFHHGKB_02310 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GPFHHGKB_02311 4e-23 relB L RelB antitoxin
GPFHHGKB_02313 8.3e-172 S Putative peptidoglycan binding domain
GPFHHGKB_02314 1.2e-31 K Transcriptional regulator, MarR family
GPFHHGKB_02315 2e-215 XK27_09600 V ABC transporter, ATP-binding protein
GPFHHGKB_02316 1.1e-229 V ABC transporter transmembrane region
GPFHHGKB_02318 4.3e-96 S Domain of unknown function DUF87
GPFHHGKB_02320 3.9e-105 yxeH S hydrolase
GPFHHGKB_02321 1.8e-120 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
GPFHHGKB_02322 9e-114 K response regulator
GPFHHGKB_02323 1.1e-272 vicK 2.7.13.3 T Histidine kinase
GPFHHGKB_02324 1.3e-102 yycH S YycH protein
GPFHHGKB_02325 2.1e-79 yycI S YycH protein
GPFHHGKB_02326 6.8e-30 yyaQ S YjbR
GPFHHGKB_02327 1.7e-116 vicX 3.1.26.11 S domain protein
GPFHHGKB_02328 9.6e-146 htrA 3.4.21.107 O serine protease
GPFHHGKB_02329 9.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPFHHGKB_02330 4.7e-207 G glycerol-3-phosphate transporter
GPFHHGKB_02331 3.3e-134 S interspecies interaction between organisms
GPFHHGKB_02332 6.6e-64 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
GPFHHGKB_02333 9.2e-90 asp1 S Accessory Sec system protein Asp1
GPFHHGKB_02334 5.8e-105 asp2 3.4.11.5 S Accessory Sec system protein Asp2
GPFHHGKB_02335 1e-32 asp3 S Accessory Sec system protein Asp3
GPFHHGKB_02336 3.9e-246 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)