ORF_ID e_value Gene_name EC_number CAZy COGs Description
AFMIFFLH_00001 4.3e-74 L Belongs to the 'phage' integrase family
AFMIFFLH_00003 1.3e-110 L transposase, IS605 OrfB family
AFMIFFLH_00004 1.2e-59
AFMIFFLH_00007 1.7e-92 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
AFMIFFLH_00008 3.6e-153 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AFMIFFLH_00015 7.9e-91 L PFAM Integrase catalytic region
AFMIFFLH_00016 2.6e-30 L Helix-turn-helix domain
AFMIFFLH_00017 2.9e-08 S Cysteine protease Prp
AFMIFFLH_00018 1.1e-22
AFMIFFLH_00021 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFMIFFLH_00022 1.9e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AFMIFFLH_00023 7.2e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AFMIFFLH_00024 1.1e-40 yabR J RNA binding
AFMIFFLH_00025 2.3e-18 divIC D Septum formation initiator
AFMIFFLH_00026 3.6e-31 yabO J S4 domain protein
AFMIFFLH_00027 7.3e-140 yabM S Polysaccharide biosynthesis protein
AFMIFFLH_00028 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AFMIFFLH_00029 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AFMIFFLH_00030 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AFMIFFLH_00031 1.6e-85 S (CBS) domain
AFMIFFLH_00032 8.1e-142 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFMIFFLH_00033 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AFMIFFLH_00034 7.2e-53 perR P Belongs to the Fur family
AFMIFFLH_00035 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
AFMIFFLH_00036 1.6e-93 sbcC L Putative exonuclease SbcCD, C subunit
AFMIFFLH_00037 1.8e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AFMIFFLH_00038 5.5e-45 M LysM domain protein
AFMIFFLH_00039 1.2e-276 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AFMIFFLH_00040 8.2e-86 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AFMIFFLH_00041 3e-34 ygfC K Bacterial regulatory proteins, tetR family
AFMIFFLH_00042 4.5e-101 hrtB V ABC transporter permease
AFMIFFLH_00043 2e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
AFMIFFLH_00044 4.7e-68 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AFMIFFLH_00045 0.0 helD 3.6.4.12 L DNA helicase
AFMIFFLH_00046 2e-245 yjbQ P TrkA C-terminal domain protein
AFMIFFLH_00047 1.8e-30
AFMIFFLH_00048 4.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
AFMIFFLH_00049 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AFMIFFLH_00050 6.5e-126 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AFMIFFLH_00051 2.2e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFMIFFLH_00052 1.5e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFMIFFLH_00053 6.1e-101 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFMIFFLH_00054 4.8e-53 rplQ J Ribosomal protein L17
AFMIFFLH_00055 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFMIFFLH_00056 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AFMIFFLH_00057 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFMIFFLH_00058 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AFMIFFLH_00059 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AFMIFFLH_00060 3.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AFMIFFLH_00061 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AFMIFFLH_00062 1e-67 rplO J Binds to the 23S rRNA
AFMIFFLH_00063 2.1e-22 rpmD J Ribosomal protein L30
AFMIFFLH_00064 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AFMIFFLH_00065 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AFMIFFLH_00066 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AFMIFFLH_00067 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AFMIFFLH_00068 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFMIFFLH_00069 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFMIFFLH_00070 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AFMIFFLH_00071 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AFMIFFLH_00072 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AFMIFFLH_00073 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
AFMIFFLH_00074 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AFMIFFLH_00075 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AFMIFFLH_00076 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AFMIFFLH_00077 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AFMIFFLH_00078 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFMIFFLH_00079 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AFMIFFLH_00080 1e-100 rplD J Forms part of the polypeptide exit tunnel
AFMIFFLH_00081 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AFMIFFLH_00082 3.7e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
AFMIFFLH_00083 3.6e-166 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AFMIFFLH_00084 6e-74 K rpiR family
AFMIFFLH_00085 1.3e-33 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
AFMIFFLH_00086 8e-145 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
AFMIFFLH_00087 5.8e-22 K Acetyltransferase (GNAT) domain
AFMIFFLH_00088 3.8e-182 steT E amino acid
AFMIFFLH_00089 2e-217 L Probable transposase
AFMIFFLH_00092 2.8e-18 S Replication initiator protein A (RepA) N-terminus
AFMIFFLH_00094 9.2e-178 L PFAM Integrase catalytic region
AFMIFFLH_00095 3.3e-32 recD 3.1.11.5 L Helix-hairpin-helix containing domain
AFMIFFLH_00096 8e-11 1.1.98.6, 3.6.3.14, 3.6.3.15, 4.1.1.35 L Participates in initiation and elongation during chromosome replication
AFMIFFLH_00097 1.6e-15 yvgN C Aldo keto reductase
AFMIFFLH_00098 3.1e-38 S Haem-degrading
AFMIFFLH_00099 4.2e-165 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
AFMIFFLH_00100 3.3e-163 iolT EGP Major facilitator Superfamily
AFMIFFLH_00101 5.1e-118 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
AFMIFFLH_00102 7.5e-150 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
AFMIFFLH_00103 5.8e-170 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
AFMIFFLH_00104 1.1e-174 iolT EGP Major facilitator Superfamily
AFMIFFLH_00105 1.5e-15 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
AFMIFFLH_00106 6e-88 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
AFMIFFLH_00107 2.4e-186 thrA E SAF
AFMIFFLH_00108 1.6e-26 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AFMIFFLH_00109 3.7e-73 G PTS system enzyme II sorbitol-specific factor
AFMIFFLH_00110 6.7e-94 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
AFMIFFLH_00111 2.4e-09 gutM K Glucitol operon activator protein (GutM)
AFMIFFLH_00112 3.4e-79 K sugar-binding domain protein
AFMIFFLH_00113 2.7e-88 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AFMIFFLH_00114 1.6e-277 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AFMIFFLH_00115 2.6e-56 K helix_turn_helix gluconate operon transcriptional repressor
AFMIFFLH_00116 1.8e-111 garR 1.1.1.60 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
AFMIFFLH_00117 2.6e-152 S Protein conserved in bacteria
AFMIFFLH_00118 4.6e-127 gntT EG Gluconate
AFMIFFLH_00120 7.8e-57 S COG NOG19168 non supervised orthologous group
AFMIFFLH_00121 1.9e-11 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
AFMIFFLH_00122 1.4e-28 S RelE-like toxin of type II toxin-antitoxin system HigB
AFMIFFLH_00123 9.3e-28 higA K Helix-turn-helix XRE-family like proteins
AFMIFFLH_00125 3.1e-192 XK27_11280 S Psort location CytoplasmicMembrane, score
AFMIFFLH_00127 1.4e-88 L Belongs to the 'phage' integrase family
AFMIFFLH_00128 3.6e-52 tlpA2 L Transposase IS200 like
AFMIFFLH_00129 2.7e-90 L Transposase, IS605 OrfB family
AFMIFFLH_00130 1.4e-08 L Belongs to the 'phage' integrase family
AFMIFFLH_00131 1.3e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
AFMIFFLH_00132 3.6e-58 hsdM 2.1.1.72 V HsdM N-terminal domain
AFMIFFLH_00134 1.1e-164 L T/G mismatch-specific endonuclease activity
AFMIFFLH_00135 2.2e-61
AFMIFFLH_00136 3.2e-67
AFMIFFLH_00138 7.6e-90 S SIR2-like domain
AFMIFFLH_00139 9.8e-237 S Domain of unknown function DUF87
AFMIFFLH_00141 1.4e-94 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
AFMIFFLH_00142 1.6e-18 K Transcriptional
AFMIFFLH_00143 2.1e-96 L Type II restriction endonuclease, TdeIII
AFMIFFLH_00144 2.4e-90 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
AFMIFFLH_00147 5.6e-168 potE2 E amino acid
AFMIFFLH_00148 4.3e-16 ald 1.4.1.1 C Belongs to the AlaDH PNT family
AFMIFFLH_00149 4.7e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AFMIFFLH_00150 1.2e-56 racA K Domain of unknown function (DUF1836)
AFMIFFLH_00151 4.1e-81 yitS S EDD domain protein, DegV family
AFMIFFLH_00152 6.4e-36 S Enterocin A Immunity
AFMIFFLH_00153 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AFMIFFLH_00154 0.0 O Belongs to the peptidase S8 family
AFMIFFLH_00155 1e-82 soj D CobQ CobB MinD ParA nucleotide binding domain protein
AFMIFFLH_00156 2.8e-28 L HTH-like domain
AFMIFFLH_00158 3.4e-103 yvgN C Aldo keto reductase
AFMIFFLH_00159 1.5e-12 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
AFMIFFLH_00163 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
AFMIFFLH_00164 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AFMIFFLH_00165 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AFMIFFLH_00166 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AFMIFFLH_00167 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
AFMIFFLH_00168 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AFMIFFLH_00169 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AFMIFFLH_00170 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
AFMIFFLH_00171 4.1e-08 KT PspC domain protein
AFMIFFLH_00172 2.9e-84 phoR 2.7.13.3 T Histidine kinase
AFMIFFLH_00173 3.5e-86 K response regulator
AFMIFFLH_00174 4.5e-67 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
AFMIFFLH_00175 1.1e-163 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AFMIFFLH_00176 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AFMIFFLH_00177 9.1e-95 yeaN P Major Facilitator Superfamily
AFMIFFLH_00178 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AFMIFFLH_00179 3.7e-117 sip L Belongs to the 'phage' integrase family
AFMIFFLH_00180 7.6e-09 E IrrE N-terminal-like domain
AFMIFFLH_00181 3.9e-35 K Helix-turn-helix XRE-family like proteins
AFMIFFLH_00182 1.1e-07 K Helix-turn-helix XRE-family like proteins
AFMIFFLH_00183 1.4e-44 S Phage regulatory protein Rha (Phage_pRha)
AFMIFFLH_00190 2.8e-44 L Bifunctional DNA primase/polymerase, N-terminal
AFMIFFLH_00191 5.4e-135 S D5 N terminal like
AFMIFFLH_00192 5.3e-11
AFMIFFLH_00194 1.2e-46 comFC S Competence protein
AFMIFFLH_00195 5.4e-128 comFA L Helicase C-terminal domain protein
AFMIFFLH_00196 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
AFMIFFLH_00197 4.1e-296 ydaO E amino acid
AFMIFFLH_00198 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
AFMIFFLH_00199 1.8e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AFMIFFLH_00200 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AFMIFFLH_00201 2.4e-33 S CAAX protease self-immunity
AFMIFFLH_00202 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AFMIFFLH_00203 1.8e-252 uup S ABC transporter, ATP-binding protein
AFMIFFLH_00204 1.4e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AFMIFFLH_00205 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
AFMIFFLH_00206 4.1e-69 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
AFMIFFLH_00207 2.3e-139 ansA 3.5.1.1 EJ Asparaginase
AFMIFFLH_00208 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
AFMIFFLH_00209 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AFMIFFLH_00210 1.4e-40 yabA L Involved in initiation control of chromosome replication
AFMIFFLH_00211 1.4e-83 holB 2.7.7.7 L DNA polymerase III
AFMIFFLH_00212 4.7e-66 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AFMIFFLH_00213 1.8e-127 tnp L DDE domain
AFMIFFLH_00214 1.5e-33
AFMIFFLH_00227 2.1e-07
AFMIFFLH_00230 4.2e-97
AFMIFFLH_00232 3.2e-53 zur P Belongs to the Fur family
AFMIFFLH_00233 1.7e-212 yfnA E Amino Acid
AFMIFFLH_00234 2.8e-250 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AFMIFFLH_00235 0.0 L Helicase C-terminal domain protein
AFMIFFLH_00236 2e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
AFMIFFLH_00237 2.1e-180 yhdP S Transporter associated domain
AFMIFFLH_00238 1.3e-26
AFMIFFLH_00239 9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFMIFFLH_00240 4.8e-131 bacI V MacB-like periplasmic core domain
AFMIFFLH_00241 1.3e-96 V ABC transporter
AFMIFFLH_00242 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFMIFFLH_00243 8.9e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
AFMIFFLH_00244 3.6e-140 V MatE
AFMIFFLH_00245 7e-44 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFMIFFLH_00246 1.3e-87 S Alpha beta hydrolase
AFMIFFLH_00247 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AFMIFFLH_00248 2.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AFMIFFLH_00249 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
AFMIFFLH_00250 1.4e-101 IQ Enoyl-(Acyl carrier protein) reductase
AFMIFFLH_00251 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
AFMIFFLH_00252 1.5e-54 queT S QueT transporter
AFMIFFLH_00254 1.5e-65 degV S Uncharacterised protein, DegV family COG1307
AFMIFFLH_00255 3e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFMIFFLH_00256 2.1e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFMIFFLH_00257 3.2e-34 trxA O Belongs to the thioredoxin family
AFMIFFLH_00258 2.5e-86 S Sucrose-6F-phosphate phosphohydrolase
AFMIFFLH_00259 1.2e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AFMIFFLH_00260 6.3e-49 S Threonine/Serine exporter, ThrE
AFMIFFLH_00261 4.3e-82 thrE S Putative threonine/serine exporter
AFMIFFLH_00262 3.1e-27 cspC K Cold shock protein
AFMIFFLH_00263 6.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
AFMIFFLH_00264 4.5e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
AFMIFFLH_00265 1.6e-22
AFMIFFLH_00266 1.2e-58 3.6.1.27 I phosphatase
AFMIFFLH_00267 2.8e-26
AFMIFFLH_00268 3.6e-66 I alpha/beta hydrolase fold
AFMIFFLH_00269 1.3e-38 azlD S branched-chain amino acid
AFMIFFLH_00270 1.9e-104 azlC E AzlC protein
AFMIFFLH_00271 2e-17
AFMIFFLH_00272 8.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
AFMIFFLH_00273 6.1e-103 V domain protein
AFMIFFLH_00274 4e-16
AFMIFFLH_00276 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AFMIFFLH_00277 2.4e-172 malY 4.4.1.8 E Aminotransferase, class I
AFMIFFLH_00278 1.2e-117 K AI-2E family transporter
AFMIFFLH_00279 3.1e-61 EG EamA-like transporter family
AFMIFFLH_00280 3.9e-76 L haloacid dehalogenase-like hydrolase
AFMIFFLH_00281 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AFMIFFLH_00282 4.3e-26 1.5.1.38 S NADPH-dependent FMN reductase
AFMIFFLH_00283 1.3e-24 1.5.1.38 S FMN reductase
AFMIFFLH_00284 7.3e-94 C Luciferase-like monooxygenase
AFMIFFLH_00285 1.4e-21 C Luciferase-like monooxygenase
AFMIFFLH_00288 5.4e-275 rny D peptidase
AFMIFFLH_00289 2.3e-81 S Phage tail protein
AFMIFFLH_00290 1.3e-106 M Phage tail tape measure protein TP901
AFMIFFLH_00292 2.1e-24 S Phage tail tube protein
AFMIFFLH_00294 2.7e-12 S Bacteriophage HK97-gp10, putative tail-component
AFMIFFLH_00296 1.8e-13 L Phage gp6-like head-tail connector protein
AFMIFFLH_00297 1.1e-94 S Phage capsid family
AFMIFFLH_00298 4.7e-73 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
AFMIFFLH_00299 4.7e-102 S Phage portal protein, HK97 family
AFMIFFLH_00300 1.1e-216 S Terminase
AFMIFFLH_00301 2.9e-33 L Phage terminase, small subunit
AFMIFFLH_00302 1.7e-22 L HNH nucleases
AFMIFFLH_00304 3.8e-16
AFMIFFLH_00307 1.1e-56 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
AFMIFFLH_00314 1.8e-62 Q DNA (cytosine-5-)-methyltransferase activity
AFMIFFLH_00317 2.2e-30
AFMIFFLH_00318 4e-68 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
AFMIFFLH_00320 4.5e-60 L Belongs to the 'phage' integrase family
AFMIFFLH_00321 4.2e-27 S HNH endonuclease
AFMIFFLH_00322 9.1e-08
AFMIFFLH_00326 3.8e-36 L Psort location Cytoplasmic, score 8.96
AFMIFFLH_00329 1.2e-157 S Phage plasmid primase, P4 family
AFMIFFLH_00330 1.9e-178 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
AFMIFFLH_00331 1.9e-35 S Protein of unknown function (DUF669)
AFMIFFLH_00332 9.5e-127 L AAA domain
AFMIFFLH_00333 2e-25 L VRR_NUC
AFMIFFLH_00334 1.4e-18
AFMIFFLH_00336 6.4e-112 L snf2 family
AFMIFFLH_00341 4.8e-19 S Domain of unknown function (DUF771)
AFMIFFLH_00344 1.3e-33 K Phage regulatory protein
AFMIFFLH_00345 2.5e-13 K Helix-turn-helix XRE-family like proteins
AFMIFFLH_00346 2.9e-29 K Helix-turn-helix XRE-family like proteins
AFMIFFLH_00347 4.4e-15 E IrrE N-terminal-like domain
AFMIFFLH_00348 2.1e-11 M Host cell surface-exposed lipoprotein
AFMIFFLH_00352 7.9e-14
AFMIFFLH_00353 1.6e-112 L Belongs to the 'phage' integrase family
AFMIFFLH_00354 2.8e-279 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AFMIFFLH_00355 2.4e-44 S Repeat protein
AFMIFFLH_00356 8.9e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
AFMIFFLH_00357 9.5e-48 M Exporter of polyketide antibiotics
AFMIFFLH_00358 2e-93 M Exporter of polyketide antibiotics
AFMIFFLH_00359 2.2e-204 G PTS system Galactitol-specific IIC component
AFMIFFLH_00361 9e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AFMIFFLH_00362 3e-155 amtB P ammonium transporter
AFMIFFLH_00363 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
AFMIFFLH_00364 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AFMIFFLH_00365 2.9e-149 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
AFMIFFLH_00366 2.9e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFMIFFLH_00367 1.2e-103 pfoS S Phosphotransferase system, EIIC
AFMIFFLH_00369 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AFMIFFLH_00370 2.5e-44 adhR K helix_turn_helix, mercury resistance
AFMIFFLH_00371 5.2e-137 purR 2.4.2.7 F pur operon repressor
AFMIFFLH_00372 5.6e-47 EGP Transmembrane secretion effector
AFMIFFLH_00373 5.1e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AFMIFFLH_00374 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFMIFFLH_00375 1.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AFMIFFLH_00377 5.8e-112 dkg S reductase
AFMIFFLH_00378 1.3e-24
AFMIFFLH_00379 9.3e-62 L Resolvase, N-terminal domain
AFMIFFLH_00380 1.4e-99 L Probable transposase
AFMIFFLH_00381 1e-78 2.4.2.3 F Phosphorylase superfamily
AFMIFFLH_00382 1.4e-290 ybiT S ABC transporter, ATP-binding protein
AFMIFFLH_00383 1.5e-62 bCE_4747 S Beta-lactamase superfamily domain
AFMIFFLH_00384 1.3e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AFMIFFLH_00385 3e-124 S overlaps another CDS with the same product name
AFMIFFLH_00386 2.9e-86 S overlaps another CDS with the same product name
AFMIFFLH_00388 6e-57 spoVK O ATPase family associated with various cellular activities (AAA)
AFMIFFLH_00389 3.6e-24 L Eco57I restriction-modification methylase
AFMIFFLH_00390 1.4e-70 L recombinase activity
AFMIFFLH_00391 4.1e-73
AFMIFFLH_00392 2.8e-22
AFMIFFLH_00393 1.2e-70 ydcZ S Putative inner membrane exporter, YdcZ
AFMIFFLH_00394 1.7e-87 S hydrolase
AFMIFFLH_00395 2.5e-205 ywfO S HD domain protein
AFMIFFLH_00396 4.4e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
AFMIFFLH_00397 1.8e-32 ywiB S Domain of unknown function (DUF1934)
AFMIFFLH_00398 9.9e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AFMIFFLH_00399 3.3e-289 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AFMIFFLH_00402 1.6e-201 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFMIFFLH_00403 4.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AFMIFFLH_00404 1.4e-40 rpmE2 J Ribosomal protein L31
AFMIFFLH_00405 8e-61
AFMIFFLH_00406 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AFMIFFLH_00407 3e-101 ftsW D Belongs to the SEDS family
AFMIFFLH_00408 3.3e-148 manN G system, mannose fructose sorbose family IID component
AFMIFFLH_00409 7e-115 manY G PTS system
AFMIFFLH_00410 1e-147 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
AFMIFFLH_00411 0.0 typA T GTP-binding protein TypA
AFMIFFLH_00412 6.3e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
AFMIFFLH_00413 1.2e-24 yktA S Belongs to the UPF0223 family
AFMIFFLH_00414 2.6e-30 1.1.1.27 C L-malate dehydrogenase activity
AFMIFFLH_00415 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AFMIFFLH_00416 9.5e-25
AFMIFFLH_00417 5e-23 ykzG S Belongs to the UPF0356 family
AFMIFFLH_00418 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFMIFFLH_00419 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AFMIFFLH_00420 7.8e-198 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AFMIFFLH_00421 7.8e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AFMIFFLH_00422 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AFMIFFLH_00423 6.1e-19 S Tetratricopeptide repeat
AFMIFFLH_00424 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFMIFFLH_00425 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFMIFFLH_00426 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AFMIFFLH_00427 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
AFMIFFLH_00428 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AFMIFFLH_00429 8.2e-199 yfnA E amino acid
AFMIFFLH_00430 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
AFMIFFLH_00431 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AFMIFFLH_00432 1.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AFMIFFLH_00433 3.8e-27 ylqC S Belongs to the UPF0109 family
AFMIFFLH_00434 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AFMIFFLH_00435 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AFMIFFLH_00436 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AFMIFFLH_00437 7.2e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AFMIFFLH_00438 1.3e-208 smc D Required for chromosome condensation and partitioning
AFMIFFLH_00439 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AFMIFFLH_00440 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFMIFFLH_00441 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AFMIFFLH_00442 1.5e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AFMIFFLH_00443 1.3e-238 yloV S DAK2 domain fusion protein YloV
AFMIFFLH_00444 4.5e-53 asp S Asp23 family, cell envelope-related function
AFMIFFLH_00445 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AFMIFFLH_00446 1.6e-197 dtpT U amino acid peptide transporter
AFMIFFLH_00447 1.1e-07
AFMIFFLH_00449 4.6e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFMIFFLH_00450 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
AFMIFFLH_00451 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
AFMIFFLH_00452 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AFMIFFLH_00453 1.4e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AFMIFFLH_00454 2.8e-251 yhgF K Tex-like protein N-terminal domain protein
AFMIFFLH_00455 3.6e-44 ydcK S Belongs to the SprT family
AFMIFFLH_00457 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFMIFFLH_00458 4.5e-129 mleP2 S Sodium Bile acid symporter family
AFMIFFLH_00459 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AFMIFFLH_00460 1e-33 S Enterocin A Immunity
AFMIFFLH_00461 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
AFMIFFLH_00462 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
AFMIFFLH_00463 6.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
AFMIFFLH_00464 1.6e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AFMIFFLH_00465 8.2e-154 yacL S domain protein
AFMIFFLH_00466 4.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AFMIFFLH_00467 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFMIFFLH_00468 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AFMIFFLH_00469 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFMIFFLH_00470 7e-71 yacP S YacP-like NYN domain
AFMIFFLH_00471 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AFMIFFLH_00472 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AFMIFFLH_00473 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
AFMIFFLH_00474 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AFMIFFLH_00475 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AFMIFFLH_00476 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AFMIFFLH_00477 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AFMIFFLH_00478 1.4e-54
AFMIFFLH_00479 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AFMIFFLH_00480 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFMIFFLH_00481 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFMIFFLH_00482 6.3e-45 nrdI F NrdI Flavodoxin like
AFMIFFLH_00483 2.7e-27 nrdH O Glutaredoxin
AFMIFFLH_00484 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
AFMIFFLH_00485 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AFMIFFLH_00486 5.1e-211 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFMIFFLH_00487 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AFMIFFLH_00488 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AFMIFFLH_00489 9.2e-29 yaaL S Protein of unknown function (DUF2508)
AFMIFFLH_00490 3.5e-32 S Protein of unknown function (DUF1461)
AFMIFFLH_00491 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AFMIFFLH_00492 1.9e-53 yutD S Protein of unknown function (DUF1027)
AFMIFFLH_00493 6.6e-57 S Calcineurin-like phosphoesterase
AFMIFFLH_00494 2.3e-182 cycA E Amino acid permease
AFMIFFLH_00495 4.9e-97 ytxK 2.1.1.72 L N-6 DNA Methylase
AFMIFFLH_00497 4.1e-11 S Putative Competence protein ComGF
AFMIFFLH_00499 1.5e-13
AFMIFFLH_00500 7.9e-27 comGC U competence protein ComGC
AFMIFFLH_00501 1.6e-58 comGB NU type II secretion system
AFMIFFLH_00502 6.8e-122 L ISXO2-like transposase domain
AFMIFFLH_00504 9.7e-23 3.1.21.3 V N-6 DNA Methylase
AFMIFFLH_00505 6.6e-104 3.1.21.3 L N-6 DNA Methylase
AFMIFFLH_00506 7.8e-27 comGB NU type II secretion system
AFMIFFLH_00507 2.3e-120 comGA NU Type II IV secretion system protein
AFMIFFLH_00508 1e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AFMIFFLH_00509 1.5e-119 yebC K Transcriptional regulatory protein
AFMIFFLH_00510 3.7e-42 S VanZ like family
AFMIFFLH_00511 1.3e-158 ccpA K catabolite control protein A
AFMIFFLH_00512 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AFMIFFLH_00513 3e-14
AFMIFFLH_00516 4.5e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFMIFFLH_00517 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
AFMIFFLH_00518 2.3e-65 hly S protein, hemolysin III
AFMIFFLH_00519 2.8e-40 M1-874 K Domain of unknown function (DUF1836)
AFMIFFLH_00520 9.4e-84 S membrane
AFMIFFLH_00521 3.2e-79 S VIT family
AFMIFFLH_00522 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
AFMIFFLH_00523 2.7e-56 P Plays a role in the regulation of phosphate uptake
AFMIFFLH_00524 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFMIFFLH_00525 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFMIFFLH_00526 3e-122 pstA P Phosphate transport system permease protein PstA
AFMIFFLH_00527 5.4e-119 pstC P probably responsible for the translocation of the substrate across the membrane
AFMIFFLH_00528 1.4e-97 pstS P Phosphate
AFMIFFLH_00529 3.9e-41 yjbH Q Thioredoxin
AFMIFFLH_00530 1.3e-231 pepF E oligoendopeptidase F
AFMIFFLH_00531 1.2e-67 coiA 3.6.4.12 S Competence protein
AFMIFFLH_00532 9.2e-48 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AFMIFFLH_00533 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
AFMIFFLH_00539 5.1e-08
AFMIFFLH_00546 4.3e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AFMIFFLH_00547 8.8e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AFMIFFLH_00548 4.5e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AFMIFFLH_00549 8.3e-178 thrC 4.2.3.1 E Threonine synthase
AFMIFFLH_00550 9.7e-75 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AFMIFFLH_00551 6.1e-62 S Psort location CytoplasmicMembrane, score
AFMIFFLH_00552 3.7e-87 waaB GT4 M Glycosyl transferases group 1
AFMIFFLH_00553 4.7e-59 cps3F
AFMIFFLH_00554 5.3e-70 M Domain of unknown function (DUF4422)
AFMIFFLH_00555 3.9e-163 XK27_08315 M Sulfatase
AFMIFFLH_00556 1.4e-127 S Bacterial membrane protein YfhO
AFMIFFLH_00557 3.6e-14
AFMIFFLH_00558 1.2e-53 cps3I G Acyltransferase family
AFMIFFLH_00559 1.2e-148 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
AFMIFFLH_00560 1.2e-39 2.7.7.65 T phosphorelay sensor kinase activity
AFMIFFLH_00561 1.3e-155 XK27_09615 S reductase
AFMIFFLH_00562 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
AFMIFFLH_00563 8.1e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AFMIFFLH_00564 9.5e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AFMIFFLH_00565 3.3e-311 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AFMIFFLH_00566 1.5e-43 S zinc-ribbon domain
AFMIFFLH_00567 7.7e-140 2.1.1.72, 3.1.21.3 V N-6 DNA Methylase
AFMIFFLH_00569 1.8e-86 G Peptidase_C39 like family
AFMIFFLH_00570 3.6e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AFMIFFLH_00571 5.5e-243 lysP E amino acid
AFMIFFLH_00572 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
AFMIFFLH_00573 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
AFMIFFLH_00574 1.2e-13 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AFMIFFLH_00575 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
AFMIFFLH_00576 7.6e-83 lysR5 K LysR substrate binding domain
AFMIFFLH_00577 1.7e-119 yxaA S membrane transporter protein
AFMIFFLH_00578 2.6e-32 ywjH S Protein of unknown function (DUF1634)
AFMIFFLH_00579 7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AFMIFFLH_00580 1.7e-225 pipD E Dipeptidase
AFMIFFLH_00581 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
AFMIFFLH_00582 3.3e-165 EGP Major facilitator Superfamily
AFMIFFLH_00583 4.7e-81 S L,D-transpeptidase catalytic domain
AFMIFFLH_00584 1.9e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
AFMIFFLH_00585 4.3e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AFMIFFLH_00586 7.2e-27 ydiI Q Thioesterase superfamily
AFMIFFLH_00587 5.6e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
AFMIFFLH_00588 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
AFMIFFLH_00589 6.4e-114 degV S EDD domain protein, DegV family
AFMIFFLH_00590 3.4e-226 cadA P P-type ATPase
AFMIFFLH_00591 1.8e-254 E Amino acid permease
AFMIFFLH_00592 2.1e-83 S Membrane
AFMIFFLH_00593 2e-49 cps3F
AFMIFFLH_00594 4.8e-282 fruA 2.7.1.202 GT Phosphotransferase System
AFMIFFLH_00595 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AFMIFFLH_00596 9e-88 fruR K DeoR C terminal sensor domain
AFMIFFLH_00597 1.1e-218 XK27_08635 S UPF0210 protein
AFMIFFLH_00598 4.1e-27 gcvR T Belongs to the UPF0237 family
AFMIFFLH_00599 2.3e-38
AFMIFFLH_00600 1.1e-76 E GDSL-like Lipase/Acylhydrolase family
AFMIFFLH_00601 9.2e-56 S Protein of unknown function (DUF975)
AFMIFFLH_00602 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
AFMIFFLH_00603 4e-230 lpdA 1.8.1.4 C Dehydrogenase
AFMIFFLH_00604 2.9e-179 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFMIFFLH_00605 2.8e-166 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
AFMIFFLH_00606 5.2e-177 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
AFMIFFLH_00609 2.3e-34 S Protein of unknown function (DUF4256)
AFMIFFLH_00610 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
AFMIFFLH_00611 2.4e-31 metI U ABC transporter permease
AFMIFFLH_00612 2.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFMIFFLH_00614 3.3e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
AFMIFFLH_00615 1.3e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AFMIFFLH_00616 2.3e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
AFMIFFLH_00617 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
AFMIFFLH_00618 3e-84 drgA C nitroreductase
AFMIFFLH_00619 8.8e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
AFMIFFLH_00620 9.6e-68 metI P ABC transporter permease
AFMIFFLH_00621 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFMIFFLH_00622 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
AFMIFFLH_00623 1e-143 2.1.1.14 E methionine synthase, vitamin-B12 independent
AFMIFFLH_00624 1.4e-45 yphJ 4.1.1.44 S decarboxylase
AFMIFFLH_00625 1.1e-55 yphH S Cupin domain
AFMIFFLH_00626 2.4e-46 C Flavodoxin
AFMIFFLH_00627 3.6e-56 S CAAX protease self-immunity
AFMIFFLH_00628 1.2e-102 pgm3 G phosphoglycerate mutase
AFMIFFLH_00629 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AFMIFFLH_00630 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AFMIFFLH_00631 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AFMIFFLH_00632 7.4e-67 M ErfK YbiS YcfS YnhG
AFMIFFLH_00633 3e-107 XK27_08845 S ABC transporter, ATP-binding protein
AFMIFFLH_00634 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
AFMIFFLH_00635 1e-131 ABC-SBP S ABC transporter
AFMIFFLH_00636 1.1e-158 potD P ABC transporter
AFMIFFLH_00637 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
AFMIFFLH_00638 9.5e-120 potB P ABC transporter permease
AFMIFFLH_00639 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AFMIFFLH_00640 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AFMIFFLH_00641 1.6e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
AFMIFFLH_00642 1.5e-235 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFMIFFLH_00643 3.9e-13 S Enterocin A Immunity
AFMIFFLH_00644 2.2e-16 pspC KT PspC domain
AFMIFFLH_00645 2.4e-16 S Putative adhesin
AFMIFFLH_00646 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
AFMIFFLH_00647 8.1e-38 K transcriptional regulator PadR family
AFMIFFLH_00648 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
AFMIFFLH_00649 4.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
AFMIFFLH_00650 1.2e-158 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFMIFFLH_00651 1.1e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AFMIFFLH_00652 3.5e-70 mltD CBM50 M NlpC P60 family protein
AFMIFFLH_00653 1.8e-52 manO S Domain of unknown function (DUF956)
AFMIFFLH_00654 2.1e-147 manN G system, mannose fructose sorbose family IID component
AFMIFFLH_00655 6.4e-116 manY G PTS system sorbose-specific iic component
AFMIFFLH_00656 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
AFMIFFLH_00657 4.1e-80 rbsB G sugar-binding domain protein
AFMIFFLH_00658 2.8e-97 baeS T Histidine kinase
AFMIFFLH_00659 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
AFMIFFLH_00660 1.8e-120 G Bacterial extracellular solute-binding protein
AFMIFFLH_00661 9.1e-71 S Protein of unknown function (DUF554)
AFMIFFLH_00662 1e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFMIFFLH_00663 1.9e-32 merR K MerR HTH family regulatory protein
AFMIFFLH_00664 2.1e-197 lmrB EGP Major facilitator Superfamily
AFMIFFLH_00665 7e-34 S Domain of unknown function (DUF4811)
AFMIFFLH_00666 4.3e-41 S CAAX protease self-immunity
AFMIFFLH_00667 1.5e-50 yceE S haloacid dehalogenase-like hydrolase
AFMIFFLH_00668 7.6e-74 glcR K DeoR C terminal sensor domain
AFMIFFLH_00669 1.3e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AFMIFFLH_00670 1.3e-183 lmrB EGP Major facilitator Superfamily
AFMIFFLH_00671 2.7e-54 bioY S BioY family
AFMIFFLH_00672 1.2e-93 S Predicted membrane protein (DUF2207)
AFMIFFLH_00673 1.4e-19
AFMIFFLH_00674 2.8e-36 M Glycosyltransferase group 2 family protein
AFMIFFLH_00675 7.4e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
AFMIFFLH_00676 2.8e-58 ktrA P TrkA-N domain
AFMIFFLH_00677 1.2e-114 ntpJ P Potassium uptake protein
AFMIFFLH_00678 5.3e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
AFMIFFLH_00679 1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
AFMIFFLH_00680 3.5e-216 scrB 3.2.1.26 GH32 G invertase
AFMIFFLH_00681 1.7e-147 scrR K helix_turn _helix lactose operon repressor
AFMIFFLH_00682 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
AFMIFFLH_00683 6e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AFMIFFLH_00684 1.3e-118 gla U Major intrinsic protein
AFMIFFLH_00685 5.8e-45 ykuL S CBS domain
AFMIFFLH_00686 3e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AFMIFFLH_00687 2.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AFMIFFLH_00688 2.6e-86 ykuT M mechanosensitive ion channel
AFMIFFLH_00691 3e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFMIFFLH_00692 2e-21 yheA S Belongs to the UPF0342 family
AFMIFFLH_00693 1.5e-127 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
AFMIFFLH_00694 7.8e-74 L PFAM transposase IS200-family protein
AFMIFFLH_00695 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AFMIFFLH_00697 5.4e-53 hit FG histidine triad
AFMIFFLH_00698 9.8e-95 ecsA V ABC transporter, ATP-binding protein
AFMIFFLH_00699 3.2e-71 ecsB U ABC transporter
AFMIFFLH_00700 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
AFMIFFLH_00701 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AFMIFFLH_00702 6.8e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AFMIFFLH_00703 3.1e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFMIFFLH_00706 6.3e-09
AFMIFFLH_00707 2.8e-16 L DnaD domain protein
AFMIFFLH_00714 1.3e-47 S Phage regulatory protein Rha (Phage_pRha)
AFMIFFLH_00716 6.4e-16 S sequence-specific DNA binding
AFMIFFLH_00717 2.5e-121 sip L Belongs to the 'phage' integrase family
AFMIFFLH_00718 1.2e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
AFMIFFLH_00719 2.2e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AFMIFFLH_00720 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
AFMIFFLH_00721 3.9e-69 ybhL S Belongs to the BI1 family
AFMIFFLH_00725 3.7e-16 K DNA-templated transcription, initiation
AFMIFFLH_00727 1.5e-66 H Methyltransferase domain
AFMIFFLH_00728 1.4e-77 cps2D 5.1.3.2 M RmlD substrate binding domain
AFMIFFLH_00729 3.3e-41 wecD M Acetyltransferase (GNAT) family
AFMIFFLH_00731 1.8e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
AFMIFFLH_00732 3.4e-41 S Protein of unknown function (DUF1211)
AFMIFFLH_00734 0.0 L helicase
AFMIFFLH_00735 2.7e-66 1.1.1.1 C Zinc-binding dehydrogenase
AFMIFFLH_00736 2.4e-31 S CHY zinc finger
AFMIFFLH_00737 9.5e-40 K Transcriptional regulator
AFMIFFLH_00738 5.2e-84 qorB 1.6.5.2 GM NmrA-like family
AFMIFFLH_00739 1.4e-08
AFMIFFLH_00740 7.9e-43 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
AFMIFFLH_00741 6.5e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
AFMIFFLH_00742 3.6e-81
AFMIFFLH_00743 4.4e-82 yjfP S COG1073 Hydrolases of the alpha beta superfamily
AFMIFFLH_00744 1.8e-113 yitU 3.1.3.104 S hydrolase
AFMIFFLH_00745 1.9e-60 speG J Acetyltransferase (GNAT) domain
AFMIFFLH_00746 7e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AFMIFFLH_00747 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
AFMIFFLH_00748 1.2e-205 pipD E Dipeptidase
AFMIFFLH_00749 2.3e-45
AFMIFFLH_00750 1.2e-64 K helix_turn_helix, arabinose operon control protein
AFMIFFLH_00751 2.7e-44 S Membrane
AFMIFFLH_00752 0.0 rafA 3.2.1.22 G alpha-galactosidase
AFMIFFLH_00753 1.9e-93 L Helicase C-terminal domain protein
AFMIFFLH_00754 6.2e-42 L Helicase C-terminal domain protein
AFMIFFLH_00756 3.6e-145 pbuO_1 S Permease family
AFMIFFLH_00757 3.8e-188 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
AFMIFFLH_00758 2.1e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
AFMIFFLH_00759 1.7e-117 M Core-2/I-Branching enzyme
AFMIFFLH_00760 9.1e-92 rfbP M Bacterial sugar transferase
AFMIFFLH_00761 2.4e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AFMIFFLH_00762 2.1e-111 ywqE 3.1.3.48 GM PHP domain protein
AFMIFFLH_00763 5.9e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
AFMIFFLH_00764 1.7e-73 epsB M biosynthesis protein
AFMIFFLH_00766 5.5e-115 cps2J S Polysaccharide biosynthesis protein
AFMIFFLH_00767 1.5e-67 S Polysaccharide pyruvyl transferase
AFMIFFLH_00769 4.5e-28 M Glycosyltransferase like family 2
AFMIFFLH_00770 3.3e-90
AFMIFFLH_00771 4.1e-38 M group 2 family protein
AFMIFFLH_00772 7.5e-98 M Glycosyl transferase family 8
AFMIFFLH_00773 2.5e-83 S response to antibiotic
AFMIFFLH_00774 4.4e-27 S zinc-ribbon domain
AFMIFFLH_00775 3.6e-117 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
AFMIFFLH_00776 3.6e-130 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AFMIFFLH_00777 6.8e-179 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AFMIFFLH_00778 9.4e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AFMIFFLH_00779 3.6e-141 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AFMIFFLH_00780 8.6e-62 S Glycosyltransferase like family 2
AFMIFFLH_00781 5.8e-117 cps1D M Domain of unknown function (DUF4422)
AFMIFFLH_00782 9.5e-38 S CAAX protease self-immunity
AFMIFFLH_00783 1.6e-88 yvyE 3.4.13.9 S YigZ family
AFMIFFLH_00784 3.9e-58 S Haloacid dehalogenase-like hydrolase
AFMIFFLH_00785 2.6e-154 EGP Major facilitator Superfamily
AFMIFFLH_00787 1.2e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
AFMIFFLH_00788 1.2e-27 K helix_turn_helix, mercury resistance
AFMIFFLH_00789 1.9e-88 S NADPH-dependent FMN reductase
AFMIFFLH_00791 1.1e-149 EGP Sugar (and other) transporter
AFMIFFLH_00792 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
AFMIFFLH_00793 6.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AFMIFFLH_00794 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AFMIFFLH_00795 8.7e-65 alkD L DNA alkylation repair enzyme
AFMIFFLH_00796 3.8e-136 EG EamA-like transporter family
AFMIFFLH_00797 3.6e-150 S Tetratricopeptide repeat protein
AFMIFFLH_00798 3.4e-204 hisS 6.1.1.21 J histidyl-tRNA synthetase
AFMIFFLH_00799 8.7e-299 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AFMIFFLH_00800 7e-127 corA P CorA-like Mg2+ transporter protein
AFMIFFLH_00802 8.5e-161 nhaC C Na H antiporter NhaC
AFMIFFLH_00803 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AFMIFFLH_00804 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
AFMIFFLH_00806 2.5e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AFMIFFLH_00807 1.3e-159 iscS 2.8.1.7 E Aminotransferase class V
AFMIFFLH_00808 3.7e-41 XK27_04120 S Putative amino acid metabolism
AFMIFFLH_00809 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AFMIFFLH_00810 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AFMIFFLH_00811 4.3e-15 S Protein of unknown function (DUF2929)
AFMIFFLH_00812 0.0 dnaE 2.7.7.7 L DNA polymerase
AFMIFFLH_00813 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AFMIFFLH_00814 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AFMIFFLH_00815 3.1e-124 ubiE_2 Q Thiopurine S-methyltransferase (TPMT)
AFMIFFLH_00816 4.5e-21 K Cold shock
AFMIFFLH_00817 1.8e-155 mreB D cell shape determining protein MreB
AFMIFFLH_00818 2.1e-88 mreC M Involved in formation and maintenance of cell shape
AFMIFFLH_00819 5.2e-55 mreD M rod shape-determining protein MreD
AFMIFFLH_00820 1.4e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
AFMIFFLH_00821 1.8e-126 minD D Belongs to the ParA family
AFMIFFLH_00822 1.8e-92 glnP P ABC transporter permease
AFMIFFLH_00823 1.1e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AFMIFFLH_00824 2.4e-108 aatB ET ABC transporter substrate-binding protein
AFMIFFLH_00825 6.3e-99 D Alpha beta
AFMIFFLH_00826 2.7e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
AFMIFFLH_00827 3.4e-08 S Protein of unknown function (DUF3397)
AFMIFFLH_00828 5.2e-64 mraZ K Belongs to the MraZ family
AFMIFFLH_00829 8.8e-141 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AFMIFFLH_00830 2.5e-11 ftsL D cell division protein FtsL
AFMIFFLH_00831 2.4e-279 ftsI 3.4.16.4 M Penicillin-binding Protein
AFMIFFLH_00832 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AFMIFFLH_00833 2e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AFMIFFLH_00834 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AFMIFFLH_00835 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AFMIFFLH_00836 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AFMIFFLH_00837 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFMIFFLH_00838 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AFMIFFLH_00839 3e-19 yggT S YGGT family
AFMIFFLH_00840 4.5e-82 ylmH S S4 domain protein
AFMIFFLH_00841 8.6e-62 divIVA D DivIVA domain protein
AFMIFFLH_00842 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AFMIFFLH_00843 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFMIFFLH_00844 5.6e-127
AFMIFFLH_00845 5.1e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
AFMIFFLH_00846 1.6e-42 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
AFMIFFLH_00847 2.3e-31 K Transcriptional regulator
AFMIFFLH_00848 1.7e-69 ybhR V ABC transporter
AFMIFFLH_00849 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
AFMIFFLH_00850 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
AFMIFFLH_00851 8.8e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFMIFFLH_00852 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFMIFFLH_00853 2.2e-270 helD 3.6.4.12 L DNA helicase
AFMIFFLH_00855 1.3e-114 htpX O Belongs to the peptidase M48B family
AFMIFFLH_00856 8.7e-72 lemA S LemA family
AFMIFFLH_00857 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
AFMIFFLH_00858 3.2e-45 yjcF K protein acetylation
AFMIFFLH_00860 3.9e-254 yfiC V ABC transporter
AFMIFFLH_00861 9.9e-223 lmrA V ABC transporter, ATP-binding protein
AFMIFFLH_00862 5.8e-35 K Bacterial regulatory proteins, tetR family
AFMIFFLH_00863 9.5e-246 yhcA V ABC transporter, ATP-binding protein
AFMIFFLH_00864 2.6e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AFMIFFLH_00865 1e-146 G Transporter, major facilitator family protein
AFMIFFLH_00866 1.6e-39 lacX 5.1.3.3 G Aldose 1-epimerase
AFMIFFLH_00867 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFMIFFLH_00868 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AFMIFFLH_00869 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
AFMIFFLH_00870 7.3e-105
AFMIFFLH_00871 3.2e-117
AFMIFFLH_00872 1.3e-41 dut S dUTPase
AFMIFFLH_00873 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AFMIFFLH_00874 3.7e-46 yqhY S Asp23 family, cell envelope-related function
AFMIFFLH_00875 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AFMIFFLH_00876 1e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AFMIFFLH_00877 8.9e-147 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFMIFFLH_00878 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFMIFFLH_00879 3.1e-82 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AFMIFFLH_00880 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AFMIFFLH_00881 6.6e-49 argR K Regulates arginine biosynthesis genes
AFMIFFLH_00882 7.1e-178 recN L May be involved in recombinational repair of damaged DNA
AFMIFFLH_00883 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AFMIFFLH_00884 2.2e-30 ynzC S UPF0291 protein
AFMIFFLH_00885 2.9e-26 yneF S UPF0154 protein
AFMIFFLH_00886 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
AFMIFFLH_00887 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
AFMIFFLH_00888 3.1e-76 yciQ P membrane protein (DUF2207)
AFMIFFLH_00889 1.8e-19 D nuclear chromosome segregation
AFMIFFLH_00890 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AFMIFFLH_00891 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AFMIFFLH_00892 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
AFMIFFLH_00893 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
AFMIFFLH_00894 4.7e-158 glk 2.7.1.2 G Glucokinase
AFMIFFLH_00895 1.4e-45 yqhL P Rhodanese-like protein
AFMIFFLH_00896 2.8e-16 WQ51_02665 S Protein of unknown function (DUF3042)
AFMIFFLH_00897 5.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AFMIFFLH_00898 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
AFMIFFLH_00899 1.3e-45 glnR K Transcriptional regulator
AFMIFFLH_00900 2e-247 glnA 6.3.1.2 E glutamine synthetase
AFMIFFLH_00901 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AFMIFFLH_00902 4e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
AFMIFFLH_00903 4.2e-21 cutC P Participates in the control of copper homeostasis
AFMIFFLH_00904 1.1e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFMIFFLH_00905 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AFMIFFLH_00906 2.1e-98 rrmA 2.1.1.187 H Methyltransferase
AFMIFFLH_00907 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AFMIFFLH_00908 1e-283 ftsK D Belongs to the FtsK SpoIIIE SftA family
AFMIFFLH_00909 1.6e-108 ymfF S Peptidase M16 inactive domain protein
AFMIFFLH_00910 2.4e-149 ymfH S Peptidase M16
AFMIFFLH_00911 2.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
AFMIFFLH_00912 2.9e-64 ymfM S Helix-turn-helix domain
AFMIFFLH_00913 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFMIFFLH_00914 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AFMIFFLH_00915 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
AFMIFFLH_00916 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AFMIFFLH_00917 2.1e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AFMIFFLH_00918 5.6e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AFMIFFLH_00919 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AFMIFFLH_00920 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AFMIFFLH_00921 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AFMIFFLH_00922 1.8e-12 yajC U Preprotein translocase
AFMIFFLH_00923 6.4e-12
AFMIFFLH_00924 3.9e-144 iunH2 3.2.2.1 F nucleoside hydrolase
AFMIFFLH_00925 1.7e-42 XK27_03960 S Protein of unknown function (DUF3013)
AFMIFFLH_00926 2.9e-117 prmA J Ribosomal protein L11 methyltransferase
AFMIFFLH_00927 4.8e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AFMIFFLH_00928 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AFMIFFLH_00929 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AFMIFFLH_00930 5.1e-57 3.1.3.18 J HAD-hyrolase-like
AFMIFFLH_00931 3.4e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AFMIFFLH_00932 1.4e-127 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFMIFFLH_00933 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AFMIFFLH_00934 3.5e-204 pyrP F Permease
AFMIFFLH_00935 1.6e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AFMIFFLH_00936 3.8e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AFMIFFLH_00937 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AFMIFFLH_00938 2e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AFMIFFLH_00939 3.7e-134 K Transcriptional regulator
AFMIFFLH_00940 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
AFMIFFLH_00941 1.1e-114 glcR K DeoR C terminal sensor domain
AFMIFFLH_00942 1.2e-171 patA 2.6.1.1 E Aminotransferase
AFMIFFLH_00943 9.2e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AFMIFFLH_00945 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AFMIFFLH_00946 6.1e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AFMIFFLH_00947 3.1e-36 rnhA 3.1.26.4 L Ribonuclease HI
AFMIFFLH_00948 1.5e-22 S Family of unknown function (DUF5322)
AFMIFFLH_00949 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AFMIFFLH_00950 1.8e-38
AFMIFFLH_00951 1.1e-60 yslB S Protein of unknown function (DUF2507)
AFMIFFLH_00952 3.6e-71 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AFMIFFLH_00953 6.7e-42 S Phosphoesterase
AFMIFFLH_00956 2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFMIFFLH_00957 1.6e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AFMIFFLH_00958 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFMIFFLH_00959 2.5e-200 oatA I Acyltransferase
AFMIFFLH_00960 4.1e-16
AFMIFFLH_00962 1.5e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AFMIFFLH_00963 2.9e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
AFMIFFLH_00964 1.4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
AFMIFFLH_00965 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AFMIFFLH_00966 2.3e-295 S membrane
AFMIFFLH_00967 1.5e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
AFMIFFLH_00968 2e-26 S Protein of unknown function (DUF3290)
AFMIFFLH_00969 2e-75 yviA S Protein of unknown function (DUF421)
AFMIFFLH_00971 3.8e-124 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AFMIFFLH_00972 1.2e-195 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AFMIFFLH_00973 4.2e-48 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
AFMIFFLH_00976 1e-09 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AFMIFFLH_00979 9.3e-12 tetR K transcriptional regulator
AFMIFFLH_00980 4.1e-15 tetR K transcriptional regulator
AFMIFFLH_00982 1.2e-41 wecD K Acetyltransferase GNAT Family
AFMIFFLH_00983 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
AFMIFFLH_00984 1.1e-70 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
AFMIFFLH_00985 5.6e-08 S SdpI/YhfL protein family
AFMIFFLH_00986 2.2e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
AFMIFFLH_00987 3.1e-286 pepO 3.4.24.71 O Peptidase family M13
AFMIFFLH_00988 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
AFMIFFLH_00989 9.1e-54 K Transcriptional regulator C-terminal region
AFMIFFLH_00990 1.6e-55 jag S R3H domain protein
AFMIFFLH_00991 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
AFMIFFLH_00992 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
AFMIFFLH_00993 5.1e-77 azlC E branched-chain amino acid
AFMIFFLH_00994 2.7e-58 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
AFMIFFLH_00995 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AFMIFFLH_00996 9.7e-91 licT K CAT RNA binding domain
AFMIFFLH_00997 6.9e-214 G phosphotransferase system
AFMIFFLH_00998 1.2e-221 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFMIFFLH_00999 1.4e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
AFMIFFLH_01000 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
AFMIFFLH_01001 1.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
AFMIFFLH_01002 4.1e-75 XK27_02070 S Nitroreductase family
AFMIFFLH_01003 1.7e-111 endA F DNA RNA non-specific endonuclease
AFMIFFLH_01005 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
AFMIFFLH_01006 1.7e-61 K Bacterial regulatory proteins, tetR family
AFMIFFLH_01007 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
AFMIFFLH_01008 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
AFMIFFLH_01009 5.6e-69 dhaL 2.7.1.121 S Dak2
AFMIFFLH_01010 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
AFMIFFLH_01011 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AFMIFFLH_01012 4.9e-176 yjcE P Sodium proton antiporter
AFMIFFLH_01013 7.5e-209 mtlR K Mga helix-turn-helix domain
AFMIFFLH_01014 1e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AFMIFFLH_01015 1e-187 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AFMIFFLH_01016 2.5e-44 M Glycosyl hydrolases family 25
AFMIFFLH_01018 4.5e-102 tcyB E ABC transporter
AFMIFFLH_01019 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AFMIFFLH_01020 2e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
AFMIFFLH_01021 1.6e-38 K Transcriptional regulator
AFMIFFLH_01022 2.2e-107 terC P Integral membrane protein TerC family
AFMIFFLH_01023 1.1e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
AFMIFFLH_01024 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFMIFFLH_01025 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
AFMIFFLH_01026 1.1e-41 gntR1 K Transcriptional regulator, GntR family
AFMIFFLH_01027 6.1e-96 V ABC transporter, ATP-binding protein
AFMIFFLH_01028 2.5e-08
AFMIFFLH_01029 1.1e-39 ybjQ S Belongs to the UPF0145 family
AFMIFFLH_01030 1.1e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
AFMIFFLH_01031 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AFMIFFLH_01032 6.1e-158 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AFMIFFLH_01033 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFMIFFLH_01034 1.1e-33
AFMIFFLH_01035 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
AFMIFFLH_01036 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AFMIFFLH_01037 8e-64 srtA 3.4.22.70 M sortase family
AFMIFFLH_01039 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
AFMIFFLH_01040 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
AFMIFFLH_01041 1.7e-184 L Probable transposase
AFMIFFLH_01042 0.0 pacL 3.6.3.8 P P-type ATPase
AFMIFFLH_01043 7.1e-109 3.1.4.46 C phosphodiesterase
AFMIFFLH_01044 2.6e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
AFMIFFLH_01045 4.7e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
AFMIFFLH_01046 2.8e-82 noc K Belongs to the ParB family
AFMIFFLH_01047 6.5e-118 soj D Sporulation initiation inhibitor
AFMIFFLH_01048 4.1e-108 spo0J K Belongs to the ParB family
AFMIFFLH_01049 9e-24 yyzM S Bacterial protein of unknown function (DUF951)
AFMIFFLH_01050 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AFMIFFLH_01051 1.9e-53 XK27_01040 S Protein of unknown function (DUF1129)
AFMIFFLH_01052 1.4e-94 S Bacterial membrane protein, YfhO
AFMIFFLH_01053 1.4e-49 I Alpha/beta hydrolase family
AFMIFFLH_01054 7.3e-14 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
AFMIFFLH_01055 1.5e-38
AFMIFFLH_01056 2.7e-104 psaA P Belongs to the bacterial solute-binding protein 9 family
AFMIFFLH_01057 1e-98 fhuC P ABC transporter
AFMIFFLH_01058 2.1e-103 znuB U ABC 3 transport family
AFMIFFLH_01059 1.5e-55 S ECF transporter, substrate-specific component
AFMIFFLH_01060 4.7e-103 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AFMIFFLH_01061 1.4e-154 oppF P Belongs to the ABC transporter superfamily
AFMIFFLH_01062 1.3e-180 oppD P Belongs to the ABC transporter superfamily
AFMIFFLH_01063 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFMIFFLH_01064 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFMIFFLH_01065 1.8e-202 oppA E ABC transporter, substratebinding protein
AFMIFFLH_01066 3.5e-218 yifK E Amino acid permease
AFMIFFLH_01067 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AFMIFFLH_01068 1.5e-56 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
AFMIFFLH_01069 5e-66 pgm3 G phosphoglycerate mutase
AFMIFFLH_01070 7.7e-253 ctpA 3.6.3.54 P P-type ATPase
AFMIFFLH_01071 4.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AFMIFFLH_01072 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AFMIFFLH_01073 2.1e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AFMIFFLH_01074 1.2e-21 K transcriptional regulator
AFMIFFLH_01075 3.2e-76 hchA S intracellular protease amidase
AFMIFFLH_01076 5.1e-137 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
AFMIFFLH_01077 1.1e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
AFMIFFLH_01078 1.9e-140 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFMIFFLH_01079 4.5e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
AFMIFFLH_01080 2.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
AFMIFFLH_01081 9.4e-94 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
AFMIFFLH_01082 7e-200 L transposition, DNA-mediated
AFMIFFLH_01083 3.1e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
AFMIFFLH_01084 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AFMIFFLH_01085 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AFMIFFLH_01086 1.5e-274 dnaK O Heat shock 70 kDa protein
AFMIFFLH_01087 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AFMIFFLH_01088 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AFMIFFLH_01089 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AFMIFFLH_01090 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AFMIFFLH_01091 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AFMIFFLH_01092 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AFMIFFLH_01093 6.8e-26 ylxQ J ribosomal protein
AFMIFFLH_01094 1.4e-39 ylxR K Protein of unknown function (DUF448)
AFMIFFLH_01095 4.8e-170 nusA K Participates in both transcription termination and antitermination
AFMIFFLH_01096 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
AFMIFFLH_01097 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFMIFFLH_01098 1.7e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AFMIFFLH_01099 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AFMIFFLH_01100 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
AFMIFFLH_01101 4.9e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AFMIFFLH_01102 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AFMIFFLH_01103 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AFMIFFLH_01104 2.7e-48 S Domain of unknown function (DUF956)
AFMIFFLH_01105 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AFMIFFLH_01107 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AFMIFFLH_01108 7.1e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
AFMIFFLH_01109 5.1e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
AFMIFFLH_01110 2.1e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AFMIFFLH_01111 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
AFMIFFLH_01112 1e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AFMIFFLH_01113 2.3e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AFMIFFLH_01114 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFMIFFLH_01115 1.1e-98 IQ reductase
AFMIFFLH_01116 5.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
AFMIFFLH_01117 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFMIFFLH_01118 8.4e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFMIFFLH_01119 4.2e-61 marR K Transcriptional regulator, MarR family
AFMIFFLH_01120 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AFMIFFLH_01121 3e-36
AFMIFFLH_01123 7.4e-182 S Protein of unknown function DUF262
AFMIFFLH_01124 6.6e-193 pepV 3.5.1.18 E dipeptidase PepV
AFMIFFLH_01125 4.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AFMIFFLH_01126 2.5e-63 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFMIFFLH_01127 6.4e-187 ytgP S Polysaccharide biosynthesis protein
AFMIFFLH_01128 2.4e-192 cycA E Amino acid permease
AFMIFFLH_01129 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFMIFFLH_01130 1.6e-176 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AFMIFFLH_01132 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AFMIFFLH_01133 1.8e-53 yiiE S Protein of unknown function (DUF1211)
AFMIFFLH_01134 0.0 asnB 6.3.5.4 E Asparagine synthase
AFMIFFLH_01135 7.4e-64 D peptidase
AFMIFFLH_01136 1.6e-116 S Glycosyl transferase family 2
AFMIFFLH_01137 1.9e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
AFMIFFLH_01138 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AFMIFFLH_01139 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AFMIFFLH_01140 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
AFMIFFLH_01141 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFMIFFLH_01142 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFMIFFLH_01143 8.4e-154 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AFMIFFLH_01144 9e-20 yaaA S S4 domain protein YaaA
AFMIFFLH_01145 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AFMIFFLH_01146 6.2e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AFMIFFLH_01147 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
AFMIFFLH_01148 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AFMIFFLH_01149 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFMIFFLH_01150 1.1e-199 nupG F Nucleoside
AFMIFFLH_01151 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
AFMIFFLH_01152 1.7e-53 K LysR substrate binding domain
AFMIFFLH_01153 1.8e-07
AFMIFFLH_01154 1.8e-65 yxkH G Polysaccharide deacetylase
AFMIFFLH_01155 9e-30 yqkB S Belongs to the HesB IscA family
AFMIFFLH_01156 3.4e-67 S Protein of unknown function (DUF1440)
AFMIFFLH_01157 5.9e-41 S Iron-sulfur cluster assembly protein
AFMIFFLH_01158 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
AFMIFFLH_01159 2.1e-72 sdaAB 4.3.1.17 E Serine dehydratase beta chain
AFMIFFLH_01160 1.1e-206 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFMIFFLH_01161 6.6e-154 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AFMIFFLH_01162 1.4e-64 G Xylose isomerase domain protein TIM barrel
AFMIFFLH_01163 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
AFMIFFLH_01164 2.9e-90 nanK GK ROK family
AFMIFFLH_01165 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
AFMIFFLH_01166 3.3e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AFMIFFLH_01167 4.3e-75 K Helix-turn-helix domain, rpiR family
AFMIFFLH_01168 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
AFMIFFLH_01169 1.8e-217 yjeM E Amino Acid
AFMIFFLH_01171 1.2e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFMIFFLH_01172 4.7e-226 tetP J elongation factor G
AFMIFFLH_01173 3.7e-17 S Protein of unknown function (DUF805)
AFMIFFLH_01174 6.1e-53 L PLD-like domain
AFMIFFLH_01175 3.7e-54 L PLD-like domain
AFMIFFLH_01177 3.2e-109 L Initiator Replication protein
AFMIFFLH_01178 2.3e-38 S Replication initiator protein A (RepA) N-terminus
AFMIFFLH_01179 3.9e-146 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFMIFFLH_01183 3.1e-32 arpU S Phage transcriptional regulator, ArpU family
AFMIFFLH_01184 1.8e-96 2.1.1.72 L Psort location Cytoplasmic, score
AFMIFFLH_01185 1.5e-22 speH 2.5.1.16, 4.1.1.50 E S-adenosylmethionine decarboxylase
AFMIFFLH_01186 6.4e-42 L transposase activity
AFMIFFLH_01187 3.1e-133 ps334 S Terminase-like family
AFMIFFLH_01188 3.9e-163 S Phage portal protein, SPP1 Gp6-like
AFMIFFLH_01189 1.8e-61 S Phage Mu protein F like protein
AFMIFFLH_01190 1.7e-12 S Domain of unknown function (DUF4355)
AFMIFFLH_01191 1.9e-104 gpG
AFMIFFLH_01192 3.2e-35 S Phage gp6-like head-tail connector protein
AFMIFFLH_01193 5.8e-12
AFMIFFLH_01194 4.5e-32
AFMIFFLH_01195 1.1e-18
AFMIFFLH_01196 4e-47
AFMIFFLH_01197 1.1e-14 S Phage tail assembly chaperone protein, TAC
AFMIFFLH_01199 2.4e-98 D NLP P60 protein
AFMIFFLH_01200 1e-77 S Phage tail protein
AFMIFFLH_01201 7.6e-79 M Prophage endopeptidase tail
AFMIFFLH_01202 6.5e-100 M Prophage endopeptidase tail
AFMIFFLH_01204 1.4e-27 S Calcineurin-like phosphoesterase
AFMIFFLH_01205 5.2e-07 N Bacterial Ig-like domain 2
AFMIFFLH_01206 6e-144 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AFMIFFLH_01208 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AFMIFFLH_01209 1.9e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AFMIFFLH_01210 2.1e-160 camS S sex pheromone
AFMIFFLH_01211 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFMIFFLH_01212 1.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AFMIFFLH_01213 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFMIFFLH_01214 9.8e-146 yegS 2.7.1.107 G Lipid kinase
AFMIFFLH_01215 2.1e-212 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFMIFFLH_01216 3.3e-18
AFMIFFLH_01217 0.0 mcrB 2.1.1.72 V ATPase family associated with various cellular activities (AAA)
AFMIFFLH_01218 6.2e-164 mcrC V Psort location Cytoplasmic, score
AFMIFFLH_01219 5.7e-09
AFMIFFLH_01220 3.2e-12 Z012_01675 S Hydrolases of the alpha beta superfamily
AFMIFFLH_01221 9.4e-31 yjaB_1 K Acetyltransferase (GNAT) domain
AFMIFFLH_01222 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFMIFFLH_01223 5.3e-68 ybbR S YbbR-like protein
AFMIFFLH_01224 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AFMIFFLH_01225 2.4e-71 S Protein of unknown function (DUF1361)
AFMIFFLH_01226 1.2e-115 murB 1.3.1.98 M Cell wall formation
AFMIFFLH_01227 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
AFMIFFLH_01228 2.5e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
AFMIFFLH_01229 1.3e-142 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
AFMIFFLH_01230 6.8e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AFMIFFLH_01231 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
AFMIFFLH_01232 3.1e-42 yxjI
AFMIFFLH_01233 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AFMIFFLH_01234 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AFMIFFLH_01235 2.8e-19 secG U Preprotein translocase
AFMIFFLH_01236 9.2e-180 clcA P chloride
AFMIFFLH_01237 6.7e-146 lmrP E Major Facilitator Superfamily
AFMIFFLH_01238 1.6e-168 T PhoQ Sensor
AFMIFFLH_01239 5e-104 K response regulator
AFMIFFLH_01240 5e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFMIFFLH_01241 4.6e-180 1.3.5.4 C FMN_bind
AFMIFFLH_01242 3.7e-56 3.1.3.48 K Transcriptional regulator
AFMIFFLH_01243 1.2e-159 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
AFMIFFLH_01244 3.1e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
AFMIFFLH_01245 8.9e-76 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
AFMIFFLH_01246 1.6e-128 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
AFMIFFLH_01247 2.3e-90 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AFMIFFLH_01248 1.2e-81 S Belongs to the UPF0246 family
AFMIFFLH_01249 2.1e-12 S CAAX protease self-immunity
AFMIFFLH_01250 1.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
AFMIFFLH_01251 3.9e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AFMIFFLH_01253 2.8e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AFMIFFLH_01254 1.2e-63 C FMN binding
AFMIFFLH_01255 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AFMIFFLH_01256 1.7e-54 rplI J Binds to the 23S rRNA
AFMIFFLH_01257 8.8e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AFMIFFLH_01258 1.4e-06
AFMIFFLH_01268 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AFMIFFLH_01269 7.2e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AFMIFFLH_01270 6.3e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AFMIFFLH_01271 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AFMIFFLH_01272 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AFMIFFLH_01274 1.6e-55 ctsR K Belongs to the CtsR family
AFMIFFLH_01275 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AFMIFFLH_01276 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFMIFFLH_01277 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFMIFFLH_01278 1.1e-59 uspA T Universal stress protein family
AFMIFFLH_01279 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
AFMIFFLH_01280 1.1e-25
AFMIFFLH_01281 2.9e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
AFMIFFLH_01282 5.2e-109 puuD S peptidase C26
AFMIFFLH_01283 4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AFMIFFLH_01284 6e-152 lsa S ABC transporter
AFMIFFLH_01285 4.7e-148 mepA V MATE efflux family protein
AFMIFFLH_01286 1.4e-38 arbx M family 8
AFMIFFLH_01288 2.4e-31 M Glycosyltransferase like family 2
AFMIFFLH_01289 3e-67 nss M transferase activity, transferring glycosyl groups
AFMIFFLH_01290 8.7e-37 M Glycosyl transferase family 8
AFMIFFLH_01291 3.2e-56 nss M transferase activity, transferring glycosyl groups
AFMIFFLH_01293 5.1e-23 arbx M family 8
AFMIFFLH_01294 1.4e-07 M Glycosyltransferase like family 2
AFMIFFLH_01295 2e-66 nss M transferase activity, transferring glycosyl groups
AFMIFFLH_01296 7.3e-109 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
AFMIFFLH_01297 5.3e-34 yxaB 2.4.1.166 GT2 M Glycosyltransferase like family 2
AFMIFFLH_01298 1.8e-151 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AFMIFFLH_01299 1.3e-39 L Helix-turn-helix domain
AFMIFFLH_01300 1.4e-10 L Helix-turn-helix domain
AFMIFFLH_01301 6.6e-81 L hmm pf00665
AFMIFFLH_01303 1.7e-23 3.2.1.18 GH33 M Rib/alpha-like repeat
AFMIFFLH_01307 2.3e-246 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AFMIFFLH_01308 1e-32 asp3 S Accessory Sec system protein Asp3
AFMIFFLH_01309 4.4e-105 asp2 3.4.11.5 S Accessory Sec system protein Asp2
AFMIFFLH_01310 9.2e-90 asp1 S Accessory Sec system protein Asp1
AFMIFFLH_01311 1.5e-63 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
AFMIFFLH_01312 3.3e-134 S interspecies interaction between organisms
AFMIFFLH_01313 4e-206 G glycerol-3-phosphate transporter
AFMIFFLH_01314 9.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AFMIFFLH_01315 1.3e-145 htrA 3.4.21.107 O serine protease
AFMIFFLH_01316 1.7e-116 vicX 3.1.26.11 S domain protein
AFMIFFLH_01317 6.8e-30 yyaQ S YjbR
AFMIFFLH_01318 2.1e-79 yycI S YycH protein
AFMIFFLH_01319 1.3e-102 yycH S YycH protein
AFMIFFLH_01320 1.5e-272 vicK 2.7.13.3 T Histidine kinase
AFMIFFLH_01321 1.5e-113 K response regulator
AFMIFFLH_01322 3.3e-09 bta 1.8.1.8 CO transport accessory protein
AFMIFFLH_01323 2.1e-153 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AFMIFFLH_01324 2.4e-172 dltB M MBOAT, membrane-bound O-acyltransferase family
AFMIFFLH_01326 2.1e-106 yxeH S hydrolase
AFMIFFLH_01327 2.4e-229 V ABC transporter transmembrane region
AFMIFFLH_01328 1.5e-215 XK27_09600 V ABC transporter, ATP-binding protein
AFMIFFLH_01329 9.3e-32 K Transcriptional regulator, MarR family
AFMIFFLH_01330 1.7e-172 S Putative peptidoglycan binding domain
AFMIFFLH_01331 6.2e-24 relB L RelB antitoxin
AFMIFFLH_01332 1.4e-61 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
AFMIFFLH_01333 8.8e-140 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
AFMIFFLH_01334 1.7e-178 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AFMIFFLH_01335 2.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFMIFFLH_01336 6e-223 pepF E Oligopeptidase F
AFMIFFLH_01337 3.7e-96 yicL EG EamA-like transporter family
AFMIFFLH_01338 3.1e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
AFMIFFLH_01339 1.6e-167 yjjP S Putative threonine/serine exporter
AFMIFFLH_01340 4.8e-109 glcU U sugar transport
AFMIFFLH_01341 5.9e-15 K regulatory protein TetR
AFMIFFLH_01342 9.9e-153 mdtG EGP Major facilitator Superfamily
AFMIFFLH_01343 5.5e-228 L COG3547 Transposase and inactivated derivatives
AFMIFFLH_01344 9.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
AFMIFFLH_01345 5.5e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
AFMIFFLH_01346 8.7e-231 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AFMIFFLH_01347 3.6e-17 yneR
AFMIFFLH_01348 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AFMIFFLH_01350 4.3e-61 uspA T universal stress protein
AFMIFFLH_01352 2e-208 yfnA E Amino Acid
AFMIFFLH_01353 9e-117 lutA C Cysteine-rich domain
AFMIFFLH_01354 3.1e-244 lutB C 4Fe-4S dicluster domain
AFMIFFLH_01355 1.6e-65 yrjD S LUD domain
AFMIFFLH_01356 3.9e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFMIFFLH_01357 7.5e-13
AFMIFFLH_01358 9.4e-122 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
AFMIFFLH_01359 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AFMIFFLH_01360 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AFMIFFLH_01361 2.1e-36 yrzL S Belongs to the UPF0297 family
AFMIFFLH_01362 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AFMIFFLH_01363 2.1e-32 yrzB S Belongs to the UPF0473 family
AFMIFFLH_01364 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AFMIFFLH_01365 2.9e-14 cvpA S Colicin V production protein
AFMIFFLH_01366 6.5e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AFMIFFLH_01367 9.9e-41 trxA O Belongs to the thioredoxin family
AFMIFFLH_01368 2.3e-26 K Transcriptional regulator, HxlR family
AFMIFFLH_01369 2.5e-170 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AFMIFFLH_01370 1.3e-102 ydhQ K UbiC transcription regulator-associated domain protein
AFMIFFLH_01371 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
AFMIFFLH_01372 1.8e-82 pncA Q isochorismatase
AFMIFFLH_01373 7.1e-64 3.1.3.73 G phosphoglycerate mutase
AFMIFFLH_01374 7.3e-259 treB G phosphotransferase system
AFMIFFLH_01375 7.5e-84 treR K UTRA
AFMIFFLH_01376 1.4e-250 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
AFMIFFLH_01377 1.9e-167 mdtG EGP Major facilitator Superfamily
AFMIFFLH_01380 1.4e-192 XK27_08315 M Sulfatase
AFMIFFLH_01381 2.9e-58 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AFMIFFLH_01382 8.8e-53 L Protein involved in initiation of plasmid replication
AFMIFFLH_01383 5.3e-18
AFMIFFLH_01386 4e-48 L Resolvase, N terminal domain
AFMIFFLH_01387 2.3e-53 S Bacterial protein of unknown function (DUF961)
AFMIFFLH_01388 1e-63 S Bacterial protein of unknown function (DUF961)
AFMIFFLH_01389 3.7e-265 D Domain of unknown function DUF87
AFMIFFLH_01390 0.0 tetP J elongation factor G
AFMIFFLH_01391 4.3e-237 tetL EGP Major Facilitator Superfamily
AFMIFFLH_01392 1.4e-178 pre D Plasmid recombination enzyme
AFMIFFLH_01396 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
AFMIFFLH_01397 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AFMIFFLH_01398 1.5e-191 KLT serine threonine protein kinase
AFMIFFLH_01399 3.3e-90 stp 3.1.3.16 T phosphatase
AFMIFFLH_01400 1.3e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AFMIFFLH_01401 1.3e-139 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AFMIFFLH_01402 4.6e-287 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFMIFFLH_01403 2.2e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AFMIFFLH_01404 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AFMIFFLH_01405 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AFMIFFLH_01406 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
AFMIFFLH_01407 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
AFMIFFLH_01408 6.1e-187 rodA D Belongs to the SEDS family
AFMIFFLH_01409 1.3e-13 S Protein of unknown function (DUF2969)
AFMIFFLH_01410 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AFMIFFLH_01411 3.4e-167 mbl D Cell shape determining protein MreB Mrl
AFMIFFLH_01412 8.5e-69 S N-acetylmuramoyl-L-alanine amidase activity
AFMIFFLH_01413 1.4e-28 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AFMIFFLH_01414 6.6e-63 licT K transcriptional antiterminator
AFMIFFLH_01415 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
AFMIFFLH_01417 3.2e-35
AFMIFFLH_01418 0.0 pepN 3.4.11.2 E aminopeptidase
AFMIFFLH_01419 3.1e-36
AFMIFFLH_01420 8.5e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AFMIFFLH_01421 2.6e-186 arsB 1.20.4.1 P Sodium Bile acid symporter family
AFMIFFLH_01422 5.2e-53 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
AFMIFFLH_01423 5.3e-263 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AFMIFFLH_01424 1.2e-177 proV E ABC transporter, ATP-binding protein
AFMIFFLH_01425 6.8e-73 gshR 1.8.1.7 C Glutathione reductase
AFMIFFLH_01428 9.8e-73 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
AFMIFFLH_01429 2.8e-14 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
AFMIFFLH_01430 1.7e-30 rusA L Endodeoxyribonuclease RusA
AFMIFFLH_01433 6.5e-31 dnaC L IstB-like ATP binding protein
AFMIFFLH_01435 9e-25 L Helix-turn-helix domain
AFMIFFLH_01436 1.4e-11 K Cro/C1-type HTH DNA-binding domain
AFMIFFLH_01438 2.2e-18
AFMIFFLH_01439 2.3e-63 S Putative HNHc nuclease
AFMIFFLH_01440 1.2e-38 S ERF superfamily
AFMIFFLH_01441 6.4e-08 S Bacteriophage Mu Gam like protein
AFMIFFLH_01444 3.4e-19
AFMIFFLH_01445 4e-48 S DNA binding
AFMIFFLH_01446 3.3e-16 K Cro/C1-type HTH DNA-binding domain
AFMIFFLH_01449 4.9e-13
AFMIFFLH_01451 1.3e-28 S sequence-specific DNA binding
AFMIFFLH_01452 1.1e-16 E Zn peptidase
AFMIFFLH_01454 3e-15 S Hypothetical protein (DUF2513)
AFMIFFLH_01455 5.4e-92 sip L Phage integrase, N-terminal SAM-like domain
AFMIFFLH_01456 7.1e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFMIFFLH_01457 4.1e-15 ywzB S Protein of unknown function (DUF1146)
AFMIFFLH_01458 2.9e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AFMIFFLH_01459 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFMIFFLH_01460 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFMIFFLH_01461 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFMIFFLH_01462 5.5e-227 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AFMIFFLH_01463 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AFMIFFLH_01464 1.2e-74 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AFMIFFLH_01465 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AFMIFFLH_01466 6e-161 purD 6.3.4.13 F Belongs to the GARS family
AFMIFFLH_01467 3e-89 S Acyltransferase family
AFMIFFLH_01471 9.4e-202 FbpA K Fibronectin-binding protein
AFMIFFLH_01472 3.1e-40 K Transcriptional regulator
AFMIFFLH_01473 3.5e-117 K Primase C terminal 1 (PriCT-1)
AFMIFFLH_01478 7.5e-07 L Integrase core domain
AFMIFFLH_01479 4.2e-40
AFMIFFLH_01491 2.6e-16 S RelB antitoxin
AFMIFFLH_01492 4.6e-37
AFMIFFLH_01493 1.1e-13
AFMIFFLH_01494 1.2e-09
AFMIFFLH_01497 5.6e-190 glnPH2 P ABC transporter permease
AFMIFFLH_01498 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AFMIFFLH_01499 2.2e-44 E GDSL-like Lipase/Acylhydrolase
AFMIFFLH_01500 1.3e-133 coaA 2.7.1.33 F Pantothenic acid kinase
AFMIFFLH_01501 7.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AFMIFFLH_01502 6.4e-48 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AFMIFFLH_01503 2.7e-68 rny D Peptidase family M23
AFMIFFLH_01505 2.3e-138 tetA EGP Major facilitator Superfamily
AFMIFFLH_01506 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
AFMIFFLH_01507 3.6e-213 yjeM E Amino Acid
AFMIFFLH_01508 1.7e-46 K Acetyltransferase (GNAT) domain
AFMIFFLH_01509 5.7e-14 ybaN S Protein of unknown function (DUF454)
AFMIFFLH_01510 1.9e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AFMIFFLH_01511 6.1e-199 frdC 1.3.5.4 C FAD binding domain
AFMIFFLH_01512 1.5e-205 yflS P Sodium:sulfate symporter transmembrane region
AFMIFFLH_01513 9.3e-37 yncA 2.3.1.79 S Maltose acetyltransferase
AFMIFFLH_01514 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFMIFFLH_01515 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
AFMIFFLH_01516 1.9e-95 ypuA S Protein of unknown function (DUF1002)
AFMIFFLH_01517 3.9e-95 3.2.1.18 GH33 M Rib/alpha-like repeat
AFMIFFLH_01518 4.7e-31 3.2.1.18 GH33 M Rib/alpha-like repeat
AFMIFFLH_01519 8.2e-07 fhaB M Rib/alpha-like repeat
AFMIFFLH_01520 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
AFMIFFLH_01522 6e-14 L PFAM Integrase catalytic region
AFMIFFLH_01523 3.3e-47 L Integrase core domain
AFMIFFLH_01524 2.6e-129 EGP Major Facilitator Superfamily
AFMIFFLH_01525 3.1e-98 EGP Major Facilitator Superfamily
AFMIFFLH_01526 6.3e-72 K Transcriptional regulator, LysR family
AFMIFFLH_01527 3.6e-138 G Xylose isomerase-like TIM barrel
AFMIFFLH_01528 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
AFMIFFLH_01529 1.6e-217 1.3.5.4 C FAD binding domain
AFMIFFLH_01530 8.4e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFMIFFLH_01531 1.2e-68 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AFMIFFLH_01532 8.4e-143 xerS L Phage integrase family
AFMIFFLH_01533 1.2e-10
AFMIFFLH_01534 1.8e-36
AFMIFFLH_01536 3.7e-14 S YjcQ protein
AFMIFFLH_01539 1.8e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
AFMIFFLH_01540 1.6e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
AFMIFFLH_01541 1.7e-76 desR K helix_turn_helix, Lux Regulon
AFMIFFLH_01542 1.4e-57 salK 2.7.13.3 T Histidine kinase
AFMIFFLH_01543 1.1e-53 yvfS V ABC-2 type transporter
AFMIFFLH_01544 6.2e-80 yvfR V ABC transporter
AFMIFFLH_01545 4.6e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AFMIFFLH_01546 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AFMIFFLH_01547 4.2e-29
AFMIFFLH_01548 6.3e-16
AFMIFFLH_01549 1.6e-112 rssA S Phospholipase, patatin family
AFMIFFLH_01550 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AFMIFFLH_01551 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
AFMIFFLH_01552 1.5e-45 S VIT family
AFMIFFLH_01553 4.2e-240 sufB O assembly protein SufB
AFMIFFLH_01554 3.2e-40 nifU C SUF system FeS assembly protein, NifU family
AFMIFFLH_01555 3.1e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AFMIFFLH_01556 6e-145 sufD O FeS assembly protein SufD
AFMIFFLH_01557 8.1e-116 sufC O FeS assembly ATPase SufC
AFMIFFLH_01558 1.2e-225 E ABC transporter, substratebinding protein
AFMIFFLH_01559 2.3e-141 yfeO P Voltage gated chloride channel
AFMIFFLH_01560 1.1e-27 K Helix-turn-helix XRE-family like proteins
AFMIFFLH_01561 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
AFMIFFLH_01562 1.8e-51 3.1.21.3 L Restriction modification system DNA specificity domain
AFMIFFLH_01563 4.9e-250 2.1.1.72 V type I restriction-modification system
AFMIFFLH_01564 1.9e-59 hsdM 2.1.1.72 V HsdM N-terminal domain
AFMIFFLH_01565 2.9e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
AFMIFFLH_01566 7.3e-136 pfoS S Phosphotransferase system, EIIC
AFMIFFLH_01567 7.2e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
AFMIFFLH_01568 4.3e-65 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
AFMIFFLH_01569 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AFMIFFLH_01570 4.2e-136 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
AFMIFFLH_01571 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
AFMIFFLH_01572 4.5e-43 gutM K Glucitol operon activator protein (GutM)
AFMIFFLH_01573 1.5e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
AFMIFFLH_01574 4e-110 IQ NAD dependent epimerase/dehydratase family
AFMIFFLH_01575 3e-48 M Phage tail tape measure protein TP901
AFMIFFLH_01577 4.3e-07
AFMIFFLH_01582 1.2e-25 S Phage minor capsid protein 2
AFMIFFLH_01583 7.9e-99 fabK 1.3.1.9 S Nitronate monooxygenase
AFMIFFLH_01584 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AFMIFFLH_01586 2.4e-265 fbp 3.1.3.11 G phosphatase activity
AFMIFFLH_01587 2.4e-70 xerD L Phage integrase, N-terminal SAM-like domain
AFMIFFLH_01588 2.2e-10 blpT
AFMIFFLH_01589 2.3e-14
AFMIFFLH_01591 1.4e-28 S Phage gp6-like head-tail connector protein
AFMIFFLH_01592 2e-97
AFMIFFLH_01593 1.3e-06 S Domain of unknown function (DUF4355)
AFMIFFLH_01596 1.1e-26 S Phage Mu protein F like protein
AFMIFFLH_01597 4.5e-16 S Phage Mu protein F like protein
AFMIFFLH_01598 2.7e-187 mtnE 2.6.1.83 E Aminotransferase
AFMIFFLH_01599 1e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
AFMIFFLH_01600 7.8e-49 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
AFMIFFLH_01601 3.5e-22 S Cytochrome B5
AFMIFFLH_01602 4e-19 sigH K DNA-templated transcription, initiation
AFMIFFLH_01603 3.4e-69 recX 2.4.1.337 GT4 S Regulatory protein RecX
AFMIFFLH_01604 6.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFMIFFLH_01605 2.6e-97 ygaC J Belongs to the UPF0374 family
AFMIFFLH_01606 2.4e-92 yueF S AI-2E family transporter
AFMIFFLH_01607 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AFMIFFLH_01608 1.8e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AFMIFFLH_01609 4e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AFMIFFLH_01610 0.0 lacL 3.2.1.23 G -beta-galactosidase
AFMIFFLH_01612 1.2e-07 L Transposase
AFMIFFLH_01613 5.7e-115 L Transposase
AFMIFFLH_01614 9.2e-206 glnP P ABC transporter
AFMIFFLH_01615 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AFMIFFLH_01616 1.5e-31
AFMIFFLH_01617 2e-111 ampC V Beta-lactamase
AFMIFFLH_01618 3.5e-110 cobQ S glutamine amidotransferase
AFMIFFLH_01619 1e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
AFMIFFLH_01620 6.8e-86 tdk 2.7.1.21 F thymidine kinase
AFMIFFLH_01621 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AFMIFFLH_01622 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AFMIFFLH_01623 1.3e-134 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AFMIFFLH_01624 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AFMIFFLH_01625 3.1e-53 tag 3.2.2.20 L glycosylase
AFMIFFLH_01626 3.2e-73 usp6 T universal stress protein
AFMIFFLH_01628 3.4e-188 rarA L recombination factor protein RarA
AFMIFFLH_01629 7.7e-24 yueI S Protein of unknown function (DUF1694)
AFMIFFLH_01630 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AFMIFFLH_01631 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
AFMIFFLH_01632 7.1e-173 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AFMIFFLH_01633 1.7e-162 iscS2 2.8.1.7 E Aminotransferase class V
AFMIFFLH_01634 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AFMIFFLH_01635 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AFMIFFLH_01636 6.4e-18 D nuclear chromosome segregation
AFMIFFLH_01638 1e-63 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
AFMIFFLH_01639 1.3e-154 2.1.1.72 V N-6 DNA Methylase
AFMIFFLH_01640 1.4e-30 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
AFMIFFLH_01641 1.5e-07
AFMIFFLH_01642 7e-60 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
AFMIFFLH_01647 1.6e-22 S PIN domain
AFMIFFLH_01648 6.9e-12 D Antitoxin component of a toxin-antitoxin (TA) module
AFMIFFLH_01649 8.6e-27 L transposase, IS605 OrfB family
AFMIFFLH_01651 6.2e-23 K Acetyltransferase (GNAT) domain
AFMIFFLH_01652 6.2e-112 natA S Domain of unknown function (DUF4162)
AFMIFFLH_01653 2.5e-84 natB CP ABC-type Na efflux pump, permease component
AFMIFFLH_01654 8.2e-87 EG EamA-like transporter family
AFMIFFLH_01655 5.8e-72 yjjH S Calcineurin-like phosphoesterase
AFMIFFLH_01656 3.7e-85 sip L Belongs to the 'phage' integrase family
AFMIFFLH_01657 5.7e-102 dam2 2.1.1.72 L DNA methyltransferase
AFMIFFLH_01658 5.9e-71 S AAA ATPase domain
AFMIFFLH_01660 7.3e-13
AFMIFFLH_01661 3.4e-18 L nuclease
AFMIFFLH_01662 9.6e-28 S Short C-terminal domain
AFMIFFLH_01663 8.9e-289 lacS G Transporter
AFMIFFLH_01664 5.9e-111 galR K Transcriptional regulator
AFMIFFLH_01665 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AFMIFFLH_01666 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AFMIFFLH_01667 5.9e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
AFMIFFLH_01668 3e-311 rafA 3.2.1.22 G alpha-galactosidase
AFMIFFLH_01669 1.1e-104 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
AFMIFFLH_01670 2.1e-21 XK27_09445 S Domain of unknown function (DUF1827)
AFMIFFLH_01672 7.5e-126 rapZ S Displays ATPase and GTPase activities
AFMIFFLH_01673 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AFMIFFLH_01674 1.8e-149 whiA K May be required for sporulation
AFMIFFLH_01675 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AFMIFFLH_01677 2.9e-137 cggR K Putative sugar-binding domain
AFMIFFLH_01678 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AFMIFFLH_01679 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AFMIFFLH_01680 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AFMIFFLH_01681 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AFMIFFLH_01682 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
AFMIFFLH_01683 3.3e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
AFMIFFLH_01684 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AFMIFFLH_01685 3.6e-220 cydD CO ABC transporter transmembrane region
AFMIFFLH_01686 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
AFMIFFLH_01687 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
AFMIFFLH_01688 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
AFMIFFLH_01690 6.5e-10 hol S Bacteriophage holin
AFMIFFLH_01691 1.7e-131 M Glycosyl hydrolases family 25
AFMIFFLH_01695 3.8e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFMIFFLH_01696 8e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
AFMIFFLH_01697 6.9e-43 yodB K Transcriptional regulator, HxlR family
AFMIFFLH_01698 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AFMIFFLH_01699 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFMIFFLH_01700 1.1e-181 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AFMIFFLH_01701 2.9e-147 V Pfam:Methyltransf_26
AFMIFFLH_01704 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFMIFFLH_01705 2.3e-208 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AFMIFFLH_01707 3.5e-19
AFMIFFLH_01708 3.2e-15 S Pfam:DUF955
AFMIFFLH_01709 4.6e-18 yvaO K Helix-turn-helix XRE-family like proteins
AFMIFFLH_01711 3.5e-119 K Phage regulatory protein
AFMIFFLH_01716 4.1e-78 S Siphovirus Gp157
AFMIFFLH_01717 2.6e-242 res L Helicase C-terminal domain protein
AFMIFFLH_01718 1.6e-116 L AAA domain
AFMIFFLH_01719 8.1e-85
AFMIFFLH_01720 9.5e-141 S Bifunctional DNA primase/polymerase, N-terminal
AFMIFFLH_01721 7.9e-230 S Virulence-associated protein E
AFMIFFLH_01722 3.1e-50 S VRR_NUC
AFMIFFLH_01726 1.5e-27 arpU S Phage transcriptional regulator, ArpU family
AFMIFFLH_01730 8.3e-88 L HNH nucleases
AFMIFFLH_01731 3.7e-60 L Phage terminase, small subunit
AFMIFFLH_01732 0.0 S Phage Terminase
AFMIFFLH_01734 8.8e-207 S Phage portal protein
AFMIFFLH_01735 9.9e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
AFMIFFLH_01736 2.2e-221 S Phage capsid family
AFMIFFLH_01737 4.8e-22 S Phage gp6-like head-tail connector protein
AFMIFFLH_01738 5.4e-59 S Phage head-tail joining protein
AFMIFFLH_01739 2.5e-65 S Bacteriophage HK97-gp10, putative tail-component
AFMIFFLH_01740 4.5e-64 S Protein of unknown function (DUF806)
AFMIFFLH_01741 2.1e-123 S Phage tail tube protein
AFMIFFLH_01742 8.2e-54 S Phage tail assembly chaperone proteins, TAC
AFMIFFLH_01744 0.0 M Phage tail tape measure protein TP901
AFMIFFLH_01745 5.5e-131 S Phage tail protein
AFMIFFLH_01746 3.3e-285 rny D peptidase
AFMIFFLH_01749 5.9e-69 S Domain of unknown function (DUF2479)
AFMIFFLH_01754 6.6e-20 S Bacteriophage holin of superfamily 6 (Holin_LLH)
AFMIFFLH_01755 5e-112 S N-acetylmuramoyl-L-alanine amidase activity
AFMIFFLH_01757 1.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AFMIFFLH_01758 1e-12 6.3.3.2 S ASCH
AFMIFFLH_01759 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
AFMIFFLH_01760 1.8e-116 degV S EDD domain protein, DegV family
AFMIFFLH_01761 1.2e-117 S Uncharacterised protein family (UPF0236)
AFMIFFLH_01764 2.6e-60 M Peptidase family M23
AFMIFFLH_01766 5.1e-28 trsE S COG0433 Predicted ATPase
AFMIFFLH_01767 4.4e-196 trsE S COG0433 Predicted ATPase
AFMIFFLH_01768 4.3e-40
AFMIFFLH_01769 6.6e-08 S Uncharacterized protein pXO2-11
AFMIFFLH_01771 2.4e-131 NU StbA protein
AFMIFFLH_01772 1.5e-86 endA F DNA RNA non-specific endonuclease
AFMIFFLH_01773 1.9e-21 ssb L Single-stranded DNA-binding protein
AFMIFFLH_01785 4.4e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
AFMIFFLH_01786 5.6e-13 S RloB-like protein
AFMIFFLH_01787 2e-57 S AAA domain, putative AbiEii toxin, Type IV TA system
AFMIFFLH_01788 6.8e-25 L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AFMIFFLH_01791 1.4e-44 3.4.22.70 M Sortase family
AFMIFFLH_01792 2.1e-89 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
AFMIFFLH_01793 8.1e-27 3.4.22.70 M Sortase family
AFMIFFLH_01794 2.2e-07 M PFAM Cna B domain protein
AFMIFFLH_01795 4.6e-22 S by MetaGeneAnnotator
AFMIFFLH_01796 1.6e-55 S N-acetylmuramoyl-L-alanine amidase activity
AFMIFFLH_01797 6.9e-37
AFMIFFLH_01798 5.8e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AFMIFFLH_01799 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AFMIFFLH_01800 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AFMIFFLH_01801 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AFMIFFLH_01802 1.7e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AFMIFFLH_01804 3.1e-111 K response regulator
AFMIFFLH_01805 1.3e-167 arlS 2.7.13.3 T Histidine kinase
AFMIFFLH_01806 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
AFMIFFLH_01807 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AFMIFFLH_01808 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AFMIFFLH_01809 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AFMIFFLH_01810 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
AFMIFFLH_01811 3.4e-89 patB 4.4.1.8 E Aminotransferase, class I
AFMIFFLH_01812 2.5e-113 K response regulator
AFMIFFLH_01813 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
AFMIFFLH_01820 5.8e-79 copY K Penicillinase repressor
AFMIFFLH_01821 0.0 3.6.3.4 P haloacid dehalogenase-like hydrolase
AFMIFFLH_01822 2.4e-40 S membrane protein (DUF2078)
AFMIFFLH_01823 4.8e-16 3.2.1.23 S Domain of unknown function DUF302
AFMIFFLH_01824 1.5e-33 3.2.1.23 S Domain of unknown function DUF302
AFMIFFLH_01825 3.2e-181 pbuG S permease
AFMIFFLH_01826 6.4e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
AFMIFFLH_01827 9e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AFMIFFLH_01828 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AFMIFFLH_01829 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AFMIFFLH_01830 1.5e-144 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFMIFFLH_01831 5.4e-13
AFMIFFLH_01832 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
AFMIFFLH_01833 1.1e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AFMIFFLH_01834 4.2e-58 radC L DNA repair protein
AFMIFFLH_01835 2.7e-202 intIA L similarity to EGAD 7942
AFMIFFLH_01836 0.0 L similarity to EGAD 8390
AFMIFFLH_01837 1.9e-57 S similarity to EGAD 6135
AFMIFFLH_01838 3.2e-144 ant 2.7.7.47 S Domain of unknown function (DUF4111)
AFMIFFLH_01839 5.2e-83 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
AFMIFFLH_01840 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
AFMIFFLH_01841 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFMIFFLH_01842 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AFMIFFLH_01843 4.1e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFMIFFLH_01844 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AFMIFFLH_01845 5.1e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AFMIFFLH_01846 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AFMIFFLH_01847 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AFMIFFLH_01848 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AFMIFFLH_01849 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
AFMIFFLH_01850 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AFMIFFLH_01851 1e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
AFMIFFLH_01852 1.1e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
AFMIFFLH_01853 3.1e-30 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
AFMIFFLH_01854 2.2e-29 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AFMIFFLH_01855 1.3e-63 S Acetyltransferase (GNAT) domain
AFMIFFLH_01856 5.7e-71 ywlG S Belongs to the UPF0340 family
AFMIFFLH_01857 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AFMIFFLH_01858 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AFMIFFLH_01859 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AFMIFFLH_01861 2.4e-47 S Short repeat of unknown function (DUF308)
AFMIFFLH_01862 4.7e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AFMIFFLH_01863 6.2e-163 oxlT P Major Facilitator Superfamily
AFMIFFLH_01864 4.5e-67 ybbL S ABC transporter
AFMIFFLH_01865 2.5e-101 ybbM S Uncharacterised protein family (UPF0014)
AFMIFFLH_01866 3e-41 ytcD K HxlR-like helix-turn-helix
AFMIFFLH_01867 2.4e-118 ytbE S reductase
AFMIFFLH_01868 3.5e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFMIFFLH_01869 9.1e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
AFMIFFLH_01870 3.1e-27 xlyB 3.5.1.28 CBM50 M LysM domain
AFMIFFLH_01871 5e-19 glpE P Rhodanese Homology Domain
AFMIFFLH_01872 4.2e-49 lytE M LysM domain protein
AFMIFFLH_01873 2.6e-91 T Calcineurin-like phosphoesterase superfamily domain
AFMIFFLH_01875 5.8e-72 2.7.7.12 C Domain of unknown function (DUF4931)
AFMIFFLH_01876 3.7e-12
AFMIFFLH_01878 3.1e-71
AFMIFFLH_01879 1.5e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
AFMIFFLH_01880 2.5e-177 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
AFMIFFLH_01881 7.9e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
AFMIFFLH_01882 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AFMIFFLH_01883 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AFMIFFLH_01884 3.5e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFMIFFLH_01885 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AFMIFFLH_01886 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AFMIFFLH_01887 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFMIFFLH_01888 3.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AFMIFFLH_01889 4.1e-51 yeaL S Protein of unknown function (DUF441)
AFMIFFLH_01890 4.8e-125 cvfB S S1 domain
AFMIFFLH_01891 3.6e-112 xerD D recombinase XerD
AFMIFFLH_01892 2.1e-292 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
AFMIFFLH_01893 2.3e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AFMIFFLH_01894 3.7e-188 nhaC C Na H antiporter NhaC
AFMIFFLH_01895 7.8e-65 ypsA S Belongs to the UPF0398 family
AFMIFFLH_01896 2.9e-198 ade 3.5.4.2 F Adenine deaminase C-terminal domain
AFMIFFLH_01898 6.3e-73 2.3.1.178 M GNAT acetyltransferase
AFMIFFLH_01899 1.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
AFMIFFLH_01900 5.7e-57 3.6.1.27 I Acid phosphatase homologues
AFMIFFLH_01901 3e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
AFMIFFLH_01903 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
AFMIFFLH_01904 8.8e-202 hsdM 2.1.1.72 V type I restriction-modification system
AFMIFFLH_01905 1.4e-76 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
AFMIFFLH_01906 6.1e-131 L Belongs to the 'phage' integrase family
AFMIFFLH_01907 1.3e-84 3.1.21.3 V Type I restriction modification DNA specificity domain
AFMIFFLH_01908 2.8e-78 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
AFMIFFLH_01909 9.7e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFMIFFLH_01910 7.6e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
AFMIFFLH_01911 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AFMIFFLH_01912 9.6e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AFMIFFLH_01913 1.2e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AFMIFFLH_01914 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AFMIFFLH_01915 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
AFMIFFLH_01916 1.3e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
AFMIFFLH_01917 1.9e-126 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
AFMIFFLH_01918 7.7e-12 M Lysin motif
AFMIFFLH_01919 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AFMIFFLH_01920 6.8e-84 lytH 3.5.1.28 M Ami_3
AFMIFFLH_01921 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
AFMIFFLH_01922 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AFMIFFLH_01923 2.8e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
AFMIFFLH_01924 4.6e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AFMIFFLH_01925 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
AFMIFFLH_01926 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
AFMIFFLH_01927 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFMIFFLH_01928 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
AFMIFFLH_01929 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFMIFFLH_01930 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AFMIFFLH_01931 5.3e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
AFMIFFLH_01932 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
AFMIFFLH_01933 7.7e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AFMIFFLH_01934 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AFMIFFLH_01935 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFMIFFLH_01936 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFMIFFLH_01937 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AFMIFFLH_01938 1e-39 ypaA S Protein of unknown function (DUF1304)
AFMIFFLH_01940 7.1e-33
AFMIFFLH_01945 9.2e-16 psiE S Phosphate-starvation-inducible E
AFMIFFLH_01946 3.5e-207 mmuP E amino acid
AFMIFFLH_01947 6.9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
AFMIFFLH_01948 5.3e-40 K LytTr DNA-binding domain
AFMIFFLH_01949 7.8e-18 S Protein of unknown function (DUF3021)
AFMIFFLH_01950 4.5e-151 yfeX P Peroxidase
AFMIFFLH_01951 6.1e-13 XK27_06935 K Transcriptional regulator C-terminal region
AFMIFFLH_01952 9.2e-104 tatD L hydrolase, TatD family
AFMIFFLH_01953 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AFMIFFLH_01954 2.4e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AFMIFFLH_01955 1.2e-22 veg S Biofilm formation stimulator VEG
AFMIFFLH_01956 8e-90 S Alpha/beta hydrolase of unknown function (DUF915)
AFMIFFLH_01957 1.7e-138 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
AFMIFFLH_01958 6.6e-46 argR K Regulates arginine biosynthesis genes
AFMIFFLH_01961 6.9e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AFMIFFLH_01962 9.7e-37 ptsH G phosphocarrier protein HPR
AFMIFFLH_01963 1.5e-15
AFMIFFLH_01964 0.0 clpE O Belongs to the ClpA ClpB family
AFMIFFLH_01965 4.7e-10
AFMIFFLH_01966 1.5e-170 gp17a S Terminase-like family
AFMIFFLH_01967 5.2e-34
AFMIFFLH_01968 3e-125 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
AFMIFFLH_01969 5.4e-85 dps P Ferritin-like domain
AFMIFFLH_01970 1.1e-14 tnp L Transposase IS66 family
AFMIFFLH_01971 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
AFMIFFLH_01972 9e-102 qmcA O prohibitin homologues
AFMIFFLH_01973 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
AFMIFFLH_01974 1.2e-89 dnaE_2 2.7.7.7 L DNA polymerase
AFMIFFLH_01975 4e-09
AFMIFFLH_01976 3.5e-43 S PD-(D/E)XK nuclease superfamily
AFMIFFLH_01977 2e-29 S DNA primase activity
AFMIFFLH_01986 1.2e-44 K Copper transport repressor CopY TcrY
AFMIFFLH_01987 6.1e-60 T Belongs to the universal stress protein A family
AFMIFFLH_01988 2.6e-41 K Bacterial regulatory proteins, tetR family
AFMIFFLH_01989 1.1e-56 K transcriptional
AFMIFFLH_01990 1.9e-68 mleR K LysR family
AFMIFFLH_01991 4.9e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
AFMIFFLH_01992 2.8e-126 mleP S Sodium Bile acid symporter family
AFMIFFLH_01993 3.2e-64 S ECF transporter, substrate-specific component
AFMIFFLH_01994 1.4e-60 acmC 3.2.1.96 NU mannosyl-glycoprotein
AFMIFFLH_01995 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AFMIFFLH_01996 2.2e-193 pbuX F xanthine permease
AFMIFFLH_01997 1.4e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
AFMIFFLH_01998 1.8e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
AFMIFFLH_01999 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
AFMIFFLH_02000 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFMIFFLH_02001 8.4e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
AFMIFFLH_02002 1.6e-159 mgtE P Acts as a magnesium transporter
AFMIFFLH_02003 1.7e-40
AFMIFFLH_02004 2.8e-34 K GNAT family
AFMIFFLH_02005 7.6e-210 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
AFMIFFLH_02006 2.4e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
AFMIFFLH_02007 1.1e-41 O ADP-ribosylglycohydrolase
AFMIFFLH_02008 6.1e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
AFMIFFLH_02009 8.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AFMIFFLH_02010 2.6e-163 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AFMIFFLH_02011 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
AFMIFFLH_02012 3.6e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
AFMIFFLH_02013 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AFMIFFLH_02014 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
AFMIFFLH_02015 3.4e-24 S Domain of unknown function (DUF4828)
AFMIFFLH_02016 1.6e-127 mocA S Oxidoreductase
AFMIFFLH_02017 2e-159 yfmL L DEAD DEAH box helicase
AFMIFFLH_02018 2e-20 S Domain of unknown function (DUF3284)
AFMIFFLH_02020 1e-279 kup P Transport of potassium into the cell
AFMIFFLH_02021 9.4e-101 malR K Transcriptional regulator, LacI family
AFMIFFLH_02022 4.3e-213 malT G Transporter, major facilitator family protein
AFMIFFLH_02023 5.9e-79 galM 5.1.3.3 G Aldose 1-epimerase
AFMIFFLH_02024 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
AFMIFFLH_02025 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
AFMIFFLH_02026 1.5e-243 E Amino acid permease
AFMIFFLH_02027 3.8e-08 E Amino acid permease
AFMIFFLH_02028 2.3e-181 pepS E Thermophilic metalloprotease (M29)
AFMIFFLH_02029 4.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AFMIFFLH_02030 1.8e-70 K Sugar-specific transcriptional regulator TrmB
AFMIFFLH_02031 3e-38 S Sulfite exporter TauE/SafE
AFMIFFLH_02032 1.8e-183 L Probable transposase
AFMIFFLH_02033 1.2e-21 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
AFMIFFLH_02034 1.2e-78 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
AFMIFFLH_02035 0.0 S Bacterial membrane protein YfhO
AFMIFFLH_02036 5.1e-53 gtcA S Teichoic acid glycosylation protein
AFMIFFLH_02037 5.1e-54 fld C Flavodoxin
AFMIFFLH_02038 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
AFMIFFLH_02039 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AFMIFFLH_02040 4.7e-12 mltD CBM50 M Lysin motif
AFMIFFLH_02041 3.8e-93 yihY S Belongs to the UPF0761 family
AFMIFFLH_02042 2.7e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AFMIFFLH_02043 3.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFMIFFLH_02044 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AFMIFFLH_02045 9.3e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
AFMIFFLH_02046 6.2e-210 glnP P ABC transporter
AFMIFFLH_02047 1.5e-10
AFMIFFLH_02048 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AFMIFFLH_02049 4.3e-99 glnH ET ABC transporter
AFMIFFLH_02050 1.2e-85 gluC P ABC transporter permease
AFMIFFLH_02051 9.6e-78 glnP P ABC transporter permease
AFMIFFLH_02052 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AFMIFFLH_02053 1e-27 ysxB J Cysteine protease Prp
AFMIFFLH_02054 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
AFMIFFLH_02057 1.2e-65 S RRXRR protein
AFMIFFLH_02060 3.3e-67 L Replication protein
AFMIFFLH_02066 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFMIFFLH_02067 1.3e-73 draG O ADP-ribosylglycohydrolase
AFMIFFLH_02069 3.7e-90 yunF F Protein of unknown function DUF72
AFMIFFLH_02070 1.7e-156 nrnB S DHHA1 domain
AFMIFFLH_02071 4.8e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
AFMIFFLH_02072 3.8e-59
AFMIFFLH_02073 2.7e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
AFMIFFLH_02075 4.3e-16 S by MetaGeneAnnotator
AFMIFFLH_02080 3.8e-40 S Bacteriophage holin family
AFMIFFLH_02085 9.6e-09 N Bacterial Ig-like domain 2
AFMIFFLH_02086 9.3e-27 S Calcineurin-like phosphoesterase
AFMIFFLH_02088 1.7e-100 M Prophage endopeptidase tail
AFMIFFLH_02089 1.7e-60 S Phage tail protein
AFMIFFLH_02090 1.2e-104 M Phage tail tape measure protein TP901
AFMIFFLH_02091 6.3e-39 S Bacteriophage Gp15 protein
AFMIFFLH_02093 7.5e-38 N domain, Protein
AFMIFFLH_02094 7.6e-17 S Minor capsid protein from bacteriophage
AFMIFFLH_02095 1e-15 S Minor capsid protein
AFMIFFLH_02096 2.6e-29 S Minor capsid protein
AFMIFFLH_02097 4.4e-14
AFMIFFLH_02098 2.5e-97 S T=7 icosahedral viral capsid
AFMIFFLH_02099 1.6e-20 S Phage minor structural protein GP20
AFMIFFLH_02102 2.3e-94 S Phage minor capsid protein 2
AFMIFFLH_02103 2.1e-144 S Phage portal protein, SPP1 Gp6-like
AFMIFFLH_02104 4.9e-166 S Pfam:Terminase_3C
AFMIFFLH_02105 2.2e-23
AFMIFFLH_02107 1e-11 arpU S Phage transcriptional regulator, ArpU family
AFMIFFLH_02113 1.7e-16
AFMIFFLH_02114 6.7e-45 S magnesium ion binding
AFMIFFLH_02115 0.0 L Primase C terminal 2 (PriCT-2)
AFMIFFLH_02116 3.4e-262 L Helicase C-terminal domain protein
AFMIFFLH_02117 2.8e-81
AFMIFFLH_02118 3.9e-40
AFMIFFLH_02119 2.3e-50
AFMIFFLH_02120 2e-104 S AAA domain
AFMIFFLH_02121 1.1e-162 D AAA domain
AFMIFFLH_02127 1.1e-18
AFMIFFLH_02128 7.5e-13 K Cro/C1-type HTH DNA-binding domain
AFMIFFLH_02129 1.3e-43 K addiction module antidote protein HigA
AFMIFFLH_02130 3.6e-37 E IrrE N-terminal-like domain
AFMIFFLH_02131 2.6e-27 S Domain of unknown function (DUF4352)
AFMIFFLH_02132 5.3e-30
AFMIFFLH_02133 8.2e-80 sip L Belongs to the 'phage' integrase family
AFMIFFLH_02134 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AFMIFFLH_02135 7.2e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
AFMIFFLH_02136 1.5e-27 yazA L GIY-YIG catalytic domain protein
AFMIFFLH_02137 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
AFMIFFLH_02138 4e-89 plsC 2.3.1.51 I Acyltransferase
AFMIFFLH_02139 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AFMIFFLH_02140 3.5e-57 yceD S Uncharacterized ACR, COG1399
AFMIFFLH_02141 1.3e-122 ylbM S Belongs to the UPF0348 family
AFMIFFLH_02142 5.5e-82 H Nodulation protein S (NodS)
AFMIFFLH_02143 5.1e-49 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AFMIFFLH_02144 2.6e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
AFMIFFLH_02145 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AFMIFFLH_02146 6e-30 yhbY J RNA-binding protein
AFMIFFLH_02147 2.7e-181 yqeH S Ribosome biogenesis GTPase YqeH
AFMIFFLH_02148 1.9e-71 yqeG S HAD phosphatase, family IIIA
AFMIFFLH_02149 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AFMIFFLH_02150 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AFMIFFLH_02151 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AFMIFFLH_02152 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFMIFFLH_02153 1.6e-107 dnaI L Primosomal protein DnaI
AFMIFFLH_02154 5.5e-80 dnaB L replication initiation and membrane attachment
AFMIFFLH_02155 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AFMIFFLH_02156 1.2e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AFMIFFLH_02157 4.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AFMIFFLH_02158 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AFMIFFLH_02159 4.7e-83 S regulation of transcription, DNA-dependent
AFMIFFLH_02161 1.3e-73 S peptidoglycan catabolic process
AFMIFFLH_02162 4.6e-247 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
AFMIFFLH_02163 1.8e-131 ylbL T Belongs to the peptidase S16 family
AFMIFFLH_02164 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AFMIFFLH_02165 1e-72 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
AFMIFFLH_02166 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
AFMIFFLH_02167 8.8e-92 dedA S SNARE associated Golgi protein
AFMIFFLH_02168 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
AFMIFFLH_02169 8.8e-50 yugI 5.3.1.9 J general stress protein
AFMIFFLH_02170 3.8e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AFMIFFLH_02171 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
AFMIFFLH_02172 1.8e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AFMIFFLH_02173 4.6e-36 pac D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AFMIFFLH_02174 4.5e-07 M cellulase activity
AFMIFFLH_02175 5.6e-156 L Transposase
AFMIFFLH_02176 1.3e-75 K sequence-specific DNA binding
AFMIFFLH_02177 8.9e-38 1.6.5.2 S NADPH-dependent FMN reductase
AFMIFFLH_02178 1.8e-160 L transposase, IS605 OrfB family
AFMIFFLH_02179 4.3e-58 tlpA2 L Transposase IS200 like
AFMIFFLH_02182 1.9e-49 tdk 2.7.1.21 F Thymidine kinase
AFMIFFLH_02184 9.3e-72 infB UW LPXTG-motif cell wall anchor domain protein
AFMIFFLH_02185 1.5e-77 infB UW LPXTG-motif cell wall anchor domain protein
AFMIFFLH_02186 1.4e-51
AFMIFFLH_02187 1.8e-82 L Transposase, IS116 IS110 IS902 family
AFMIFFLH_02188 2e-32 dprA LU DNA protecting protein DprA
AFMIFFLH_02189 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFMIFFLH_02190 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AFMIFFLH_02191 3.6e-24 yozE S Belongs to the UPF0346 family
AFMIFFLH_02192 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
AFMIFFLH_02193 6.5e-80 ypmR E GDSL-like Lipase/Acylhydrolase
AFMIFFLH_02195 3.5e-113 S Aldo keto reductase
AFMIFFLH_02196 4.2e-35 K helix_turn_helix, mercury resistance
AFMIFFLH_02197 1.6e-133 yvgN C Aldo keto reductase
AFMIFFLH_02198 4.7e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AFMIFFLH_02199 5.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFMIFFLH_02200 2.2e-276 yfmR S ABC transporter, ATP-binding protein
AFMIFFLH_02201 1.1e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AFMIFFLH_02202 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AFMIFFLH_02203 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFMIFFLH_02204 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
AFMIFFLH_02206 1.8e-56 yqeY S YqeY-like protein
AFMIFFLH_02207 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AFMIFFLH_02208 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AFMIFFLH_02211 5.8e-100 epsJ1 M Glycosyltransferase like family 2
AFMIFFLH_02212 7e-83 M Glycosyltransferase sugar-binding region containing DXD motif
AFMIFFLH_02213 6.2e-92 M transferase activity, transferring glycosyl groups
AFMIFFLH_02214 6.3e-125 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFMIFFLH_02215 2.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AFMIFFLH_02216 1.5e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AFMIFFLH_02217 5.1e-56 dnaD L DnaD domain protein
AFMIFFLH_02218 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
AFMIFFLH_02219 5.3e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AFMIFFLH_02220 1.4e-36 ypmB S Protein conserved in bacteria
AFMIFFLH_02221 3.4e-225 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AFMIFFLH_02222 9.5e-95 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
AFMIFFLH_02223 1.8e-117 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AFMIFFLH_02224 1.9e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
AFMIFFLH_02225 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AFMIFFLH_02226 8.4e-105 holA 2.7.7.7 L DNA polymerase III delta subunit
AFMIFFLH_02227 2.7e-156 comEC S Competence protein ComEC
AFMIFFLH_02228 2e-69 comEB 3.5.4.12 F ComE operon protein 2
AFMIFFLH_02229 3.1e-50 comEA L Competence protein ComEA
AFMIFFLH_02230 3.4e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
AFMIFFLH_02231 4e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AFMIFFLH_02232 2.2e-20
AFMIFFLH_02234 2.3e-122 K LysR substrate binding domain
AFMIFFLH_02235 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFMIFFLH_02236 3e-14 S Acyltransferase family
AFMIFFLH_02237 4.1e-68 sip L Belongs to the 'phage' integrase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)