ORF_ID e_value Gene_name EC_number CAZy COGs Description
MMAEJEDM_00001 2.5e-127 xerC L Belongs to the 'phage' integrase family
MMAEJEDM_00002 1e-63 hsdS 3.1.21.3 V DNA specificity domain
MMAEJEDM_00003 1.7e-131 M Glycosyl hydrolases family 25
MMAEJEDM_00004 6.5e-10 hol S Bacteriophage holin
MMAEJEDM_00008 7e-157 potE2 E amino acid
MMAEJEDM_00012 3.7e-14 S YjcQ protein
MMAEJEDM_00014 1.8e-36
MMAEJEDM_00015 1.2e-10
MMAEJEDM_00016 5.5e-228 L COG3547 Transposase and inactivated derivatives
MMAEJEDM_00017 3.6e-153 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MMAEJEDM_00018 5e-112 S N-acetylmuramoyl-L-alanine amidase activity
MMAEJEDM_00019 6.6e-20 S Bacteriophage holin of superfamily 6 (Holin_LLH)
MMAEJEDM_00021 9.2e-78 S D5 N terminal like
MMAEJEDM_00022 6.4e-12
MMAEJEDM_00023 3.9e-144 iunH2 3.2.2.1 F nucleoside hydrolase
MMAEJEDM_00024 1.7e-42 XK27_03960 S Protein of unknown function (DUF3013)
MMAEJEDM_00025 2.2e-117 prmA J Ribosomal protein L11 methyltransferase
MMAEJEDM_00026 4.8e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MMAEJEDM_00027 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MMAEJEDM_00028 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MMAEJEDM_00029 5.1e-57 3.1.3.18 J HAD-hyrolase-like
MMAEJEDM_00030 3.4e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MMAEJEDM_00031 1.4e-127 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MMAEJEDM_00032 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MMAEJEDM_00033 3.5e-204 pyrP F Permease
MMAEJEDM_00034 1.6e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MMAEJEDM_00035 3.8e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MMAEJEDM_00036 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MMAEJEDM_00037 2e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MMAEJEDM_00038 3.7e-134 K Transcriptional regulator
MMAEJEDM_00039 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
MMAEJEDM_00040 1.1e-114 glcR K DeoR C terminal sensor domain
MMAEJEDM_00041 1.2e-171 patA 2.6.1.1 E Aminotransferase
MMAEJEDM_00042 9.2e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MMAEJEDM_00044 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MMAEJEDM_00045 6.1e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MMAEJEDM_00046 3.1e-36 rnhA 3.1.26.4 L Ribonuclease HI
MMAEJEDM_00047 1.5e-22 S Family of unknown function (DUF5322)
MMAEJEDM_00048 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MMAEJEDM_00049 1.8e-38
MMAEJEDM_00051 1.1e-149 EGP Sugar (and other) transporter
MMAEJEDM_00052 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
MMAEJEDM_00053 6.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MMAEJEDM_00054 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MMAEJEDM_00055 1.6e-66 alkD L DNA alkylation repair enzyme
MMAEJEDM_00056 3.8e-136 EG EamA-like transporter family
MMAEJEDM_00057 3.6e-150 S Tetratricopeptide repeat protein
MMAEJEDM_00058 3.4e-204 hisS 6.1.1.21 J histidyl-tRNA synthetase
MMAEJEDM_00059 8.7e-299 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MMAEJEDM_00060 7e-127 corA P CorA-like Mg2+ transporter protein
MMAEJEDM_00061 8.5e-161 nhaC C Na H antiporter NhaC
MMAEJEDM_00062 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MMAEJEDM_00063 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MMAEJEDM_00065 2.5e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MMAEJEDM_00066 1.3e-159 iscS 2.8.1.7 E Aminotransferase class V
MMAEJEDM_00067 3.7e-41 XK27_04120 S Putative amino acid metabolism
MMAEJEDM_00068 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MMAEJEDM_00069 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MMAEJEDM_00070 4.3e-15 S Protein of unknown function (DUF2929)
MMAEJEDM_00071 0.0 dnaE 2.7.7.7 L DNA polymerase
MMAEJEDM_00072 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MMAEJEDM_00073 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MMAEJEDM_00074 6.5e-55 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MMAEJEDM_00075 5.2e-53 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
MMAEJEDM_00076 3.7e-98 V ABC transporter transmembrane region
MMAEJEDM_00081 2.7e-53 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MMAEJEDM_00082 0.0 O Belongs to the peptidase S8 family
MMAEJEDM_00083 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MMAEJEDM_00084 1.8e-08
MMAEJEDM_00085 2.4e-45 yjaB_1 K Acetyltransferase (GNAT) domain
MMAEJEDM_00086 4.1e-81 yitS S EDD domain protein, DegV family
MMAEJEDM_00087 5.6e-57 racA K Domain of unknown function (DUF1836)
MMAEJEDM_00088 9.4e-117 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MMAEJEDM_00089 6.6e-148 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MMAEJEDM_00090 4e-166 potE2 E amino acid
MMAEJEDM_00093 4.9e-91 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MMAEJEDM_00094 2.1e-96 L Type II restriction endonuclease, TdeIII
MMAEJEDM_00095 1.6e-18 K Transcriptional
MMAEJEDM_00096 1.4e-94 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
MMAEJEDM_00098 9.8e-237 S Domain of unknown function DUF87
MMAEJEDM_00099 7.6e-90 S SIR2-like domain
MMAEJEDM_00101 3.2e-67
MMAEJEDM_00102 2.2e-61
MMAEJEDM_00103 1.1e-164 L T/G mismatch-specific endonuclease activity
MMAEJEDM_00105 3.6e-58 hsdM 2.1.1.72 V HsdM N-terminal domain
MMAEJEDM_00106 1.3e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
MMAEJEDM_00107 1.4e-08 L Belongs to the 'phage' integrase family
MMAEJEDM_00108 1.2e-90 L Transposase, IS605 OrfB family
MMAEJEDM_00109 1e-54 tlpA2 L Transposase IS200 like
MMAEJEDM_00110 1.4e-88 L Belongs to the 'phage' integrase family
MMAEJEDM_00112 3.1e-192 XK27_11280 S Psort location CytoplasmicMembrane, score
MMAEJEDM_00114 9.3e-28 higA K Helix-turn-helix XRE-family like proteins
MMAEJEDM_00115 1.4e-28 S RelE-like toxin of type II toxin-antitoxin system HigB
MMAEJEDM_00116 7.8e-57 S COG NOG19168 non supervised orthologous group
MMAEJEDM_00118 4.6e-127 gntT EG Gluconate
MMAEJEDM_00119 2.6e-152 S Protein conserved in bacteria
MMAEJEDM_00120 1.8e-111 garR 1.1.1.60 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MMAEJEDM_00121 2.6e-56 K helix_turn_helix gluconate operon transcriptional repressor
MMAEJEDM_00122 1.6e-277 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MMAEJEDM_00123 2.7e-88 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MMAEJEDM_00124 3.4e-79 K sugar-binding domain protein
MMAEJEDM_00125 2.4e-09 gutM K Glucitol operon activator protein (GutM)
MMAEJEDM_00126 6.7e-94 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
MMAEJEDM_00127 3.7e-73 G PTS system enzyme II sorbitol-specific factor
MMAEJEDM_00128 1.6e-26 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MMAEJEDM_00129 2.4e-186 thrA E SAF
MMAEJEDM_00130 6e-88 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MMAEJEDM_00131 1.5e-15 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MMAEJEDM_00132 1.1e-174 iolT EGP Major facilitator Superfamily
MMAEJEDM_00133 5.8e-170 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MMAEJEDM_00134 7.5e-150 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MMAEJEDM_00135 5.1e-118 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MMAEJEDM_00136 2.5e-163 iolT EGP Major facilitator Superfamily
MMAEJEDM_00137 4.2e-165 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MMAEJEDM_00138 3.1e-38 S Haem-degrading
MMAEJEDM_00139 6.1e-125 yvgN C Aldo keto reductase
MMAEJEDM_00147 1.2e-44 K Copper transport repressor CopY TcrY
MMAEJEDM_00148 6.1e-60 T Belongs to the universal stress protein A family
MMAEJEDM_00149 2.6e-41 K Bacterial regulatory proteins, tetR family
MMAEJEDM_00150 1.1e-56 K transcriptional
MMAEJEDM_00151 1.9e-68 mleR K LysR family
MMAEJEDM_00152 4.9e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MMAEJEDM_00153 2.8e-126 mleP S Sodium Bile acid symporter family
MMAEJEDM_00154 3.2e-64 S ECF transporter, substrate-specific component
MMAEJEDM_00155 1.4e-60 acmC 3.2.1.96 NU mannosyl-glycoprotein
MMAEJEDM_00156 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MMAEJEDM_00157 2.2e-193 pbuX F xanthine permease
MMAEJEDM_00158 1.4e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MMAEJEDM_00159 1.8e-255 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MMAEJEDM_00160 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
MMAEJEDM_00161 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MMAEJEDM_00162 8.4e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MMAEJEDM_00163 1.6e-159 mgtE P Acts as a magnesium transporter
MMAEJEDM_00165 1.7e-40
MMAEJEDM_00166 2.8e-34 K GNAT family
MMAEJEDM_00167 2.9e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MMAEJEDM_00168 2.4e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MMAEJEDM_00169 1.1e-41 O ADP-ribosylglycohydrolase
MMAEJEDM_00170 1e-219 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MMAEJEDM_00171 8.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MMAEJEDM_00172 2.6e-163 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MMAEJEDM_00173 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
MMAEJEDM_00174 3.6e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
MMAEJEDM_00175 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MMAEJEDM_00176 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
MMAEJEDM_00177 3.4e-24 S Domain of unknown function (DUF4828)
MMAEJEDM_00178 1.6e-127 mocA S Oxidoreductase
MMAEJEDM_00179 2e-159 yfmL L DEAD DEAH box helicase
MMAEJEDM_00180 2e-20 S Domain of unknown function (DUF3284)
MMAEJEDM_00182 1e-279 kup P Transport of potassium into the cell
MMAEJEDM_00183 9.4e-101 malR K Transcriptional regulator, LacI family
MMAEJEDM_00184 4.3e-213 malT G Transporter, major facilitator family protein
MMAEJEDM_00185 5.9e-79 galM 5.1.3.3 G Aldose 1-epimerase
MMAEJEDM_00186 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MMAEJEDM_00187 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MMAEJEDM_00188 1.5e-243 E Amino acid permease
MMAEJEDM_00189 3.8e-08 E Amino acid permease
MMAEJEDM_00190 3.7e-39 pepS E Thermophilic metalloprotease (M29)
MMAEJEDM_00191 4.9e-122 pepS E Thermophilic metalloprotease (M29)
MMAEJEDM_00192 4.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MMAEJEDM_00193 1.8e-70 K Sugar-specific transcriptional regulator TrmB
MMAEJEDM_00194 3e-38 S Sulfite exporter TauE/SafE
MMAEJEDM_00195 4.2e-97
MMAEJEDM_00197 3.2e-53 zur P Belongs to the Fur family
MMAEJEDM_00198 1.7e-212 yfnA E Amino Acid
MMAEJEDM_00199 2.8e-250 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MMAEJEDM_00200 0.0 L Helicase C-terminal domain protein
MMAEJEDM_00201 2e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
MMAEJEDM_00202 2.1e-180 yhdP S Transporter associated domain
MMAEJEDM_00203 1.3e-26
MMAEJEDM_00204 9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MMAEJEDM_00205 4.8e-131 bacI V MacB-like periplasmic core domain
MMAEJEDM_00206 1.3e-96 V ABC transporter
MMAEJEDM_00207 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MMAEJEDM_00208 8.9e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
MMAEJEDM_00209 3.6e-140 V MatE
MMAEJEDM_00210 7e-44 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MMAEJEDM_00211 1.3e-87 S Alpha beta hydrolase
MMAEJEDM_00212 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MMAEJEDM_00213 2.5e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MMAEJEDM_00214 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
MMAEJEDM_00215 1.4e-101 IQ Enoyl-(Acyl carrier protein) reductase
MMAEJEDM_00216 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
MMAEJEDM_00217 1.5e-54 queT S QueT transporter
MMAEJEDM_00219 1.5e-65 degV S Uncharacterised protein, DegV family COG1307
MMAEJEDM_00220 3e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MMAEJEDM_00221 2.1e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MMAEJEDM_00222 3.2e-34 trxA O Belongs to the thioredoxin family
MMAEJEDM_00223 2.5e-86 S Sucrose-6F-phosphate phosphohydrolase
MMAEJEDM_00224 1.2e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MMAEJEDM_00225 6.3e-49 S Threonine/Serine exporter, ThrE
MMAEJEDM_00226 4.3e-82 thrE S Putative threonine/serine exporter
MMAEJEDM_00227 3.1e-27 cspC K Cold shock protein
MMAEJEDM_00228 6.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
MMAEJEDM_00229 4.5e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MMAEJEDM_00230 1.6e-22
MMAEJEDM_00231 1.2e-58 3.6.1.27 I phosphatase
MMAEJEDM_00232 2.8e-26
MMAEJEDM_00233 3.6e-66 I alpha/beta hydrolase fold
MMAEJEDM_00234 1.3e-38 azlD S branched-chain amino acid
MMAEJEDM_00235 1.9e-104 azlC E AzlC protein
MMAEJEDM_00236 2e-17
MMAEJEDM_00237 8.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
MMAEJEDM_00238 6.1e-103 V domain protein
MMAEJEDM_00239 4e-16
MMAEJEDM_00241 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MMAEJEDM_00242 2.4e-172 malY 4.4.1.8 E Aminotransferase, class I
MMAEJEDM_00243 1.2e-117 K AI-2E family transporter
MMAEJEDM_00244 3.1e-61 EG EamA-like transporter family
MMAEJEDM_00245 3.9e-76 L haloacid dehalogenase-like hydrolase
MMAEJEDM_00246 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MMAEJEDM_00247 4.3e-26 1.5.1.38 S NADPH-dependent FMN reductase
MMAEJEDM_00248 1.3e-24 1.5.1.38 S FMN reductase
MMAEJEDM_00249 7.3e-94 C Luciferase-like monooxygenase
MMAEJEDM_00250 1.4e-21 C Luciferase-like monooxygenase
MMAEJEDM_00252 2.2e-204 G PTS system Galactitol-specific IIC component
MMAEJEDM_00253 2e-93 M Exporter of polyketide antibiotics
MMAEJEDM_00254 3e-46 M Exporter of polyketide antibiotics
MMAEJEDM_00255 3.4e-99 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MMAEJEDM_00256 2.4e-44 S Repeat protein
MMAEJEDM_00257 2.8e-279 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MMAEJEDM_00258 3.4e-115 L Belongs to the 'phage' integrase family
MMAEJEDM_00259 7.9e-14
MMAEJEDM_00261 1.3e-26 ligA 2.7.7.7, 6.5.1.2 L EXOIII
MMAEJEDM_00262 1.5e-13
MMAEJEDM_00263 3.2e-16 L nuclease
MMAEJEDM_00264 1.3e-27 S Short C-terminal domain
MMAEJEDM_00266 3.8e-38 E Zn peptidase
MMAEJEDM_00267 4.1e-37 K Helix-turn-helix XRE-family like proteins
MMAEJEDM_00268 5.9e-10 XK27_07105 K Helix-turn-helix XRE-family like proteins
MMAEJEDM_00269 8.2e-19 S Domain of unknown function (DUF771)
MMAEJEDM_00274 3.6e-54 S Putative HNHc nuclease
MMAEJEDM_00275 4e-32 L N-terminal phage replisome organiser (Phage_rep_org_N)
MMAEJEDM_00278 1.6e-25
MMAEJEDM_00279 9.7e-71
MMAEJEDM_00282 2.2e-36 L recombinase activity
MMAEJEDM_00295 1.5e-27 arpU S Phage transcriptional regulator, ArpU family
MMAEJEDM_00298 1.6e-21
MMAEJEDM_00299 1e-88 L HNH nucleases
MMAEJEDM_00300 4.3e-83 L Phage terminase, small subunit
MMAEJEDM_00301 0.0 S Phage Terminase
MMAEJEDM_00303 6.7e-207 S Phage portal protein
MMAEJEDM_00304 4.2e-119 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MMAEJEDM_00305 4.4e-222 S Phage capsid family
MMAEJEDM_00306 4.8e-22 S Phage gp6-like head-tail connector protein
MMAEJEDM_00307 1.2e-58 S Phage head-tail joining protein
MMAEJEDM_00308 5.7e-55 S Bacteriophage HK97-gp10, putative tail-component
MMAEJEDM_00309 2e-64 S Protein of unknown function (DUF806)
MMAEJEDM_00310 5.5e-124 S Phage tail tube protein
MMAEJEDM_00311 4.1e-53 S Phage tail assembly chaperone proteins, TAC
MMAEJEDM_00313 0.0 M Phage tail tape measure protein TP901
MMAEJEDM_00314 3.5e-77 S Phage tail protein
MMAEJEDM_00315 5.9e-122 rny D peptidase
MMAEJEDM_00317 5.4e-27 S Calcineurin-like phosphoesterase
MMAEJEDM_00318 9.3e-12 N Bacterial Ig-like domain 2
MMAEJEDM_00323 2.7e-13 S by MetaGeneAnnotator
MMAEJEDM_00325 3.5e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
MMAEJEDM_00326 3.4e-113 M Glycosyl hydrolases family 25
MMAEJEDM_00328 3.5e-247 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MMAEJEDM_00329 1.7e-32 asp3 S Accessory Sec system protein Asp3
MMAEJEDM_00330 1.5e-105 asp2 3.4.11.5 S Accessory Sec system protein Asp2
MMAEJEDM_00331 9.2e-90 asp1 S Accessory Sec system protein Asp1
MMAEJEDM_00332 1.5e-63 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
MMAEJEDM_00333 3.3e-134 S interspecies interaction between organisms
MMAEJEDM_00334 6.7e-206 G glycerol-3-phosphate transporter
MMAEJEDM_00335 9.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MMAEJEDM_00336 1.3e-145 htrA 3.4.21.107 O serine protease
MMAEJEDM_00337 1.7e-116 vicX 3.1.26.11 S domain protein
MMAEJEDM_00338 6.8e-30 yyaQ S YjbR
MMAEJEDM_00339 2.1e-79 yycI S YycH protein
MMAEJEDM_00340 1.3e-102 yycH S YycH protein
MMAEJEDM_00341 1.5e-272 vicK 2.7.13.3 T Histidine kinase
MMAEJEDM_00342 9e-114 K response regulator
MMAEJEDM_00343 3.3e-09 bta 1.8.1.8 CO transport accessory protein
MMAEJEDM_00344 4.6e-153 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MMAEJEDM_00345 1.9e-172 dltB M MBOAT, membrane-bound O-acyltransferase family
MMAEJEDM_00347 4.7e-106 yxeH S hydrolase
MMAEJEDM_00349 3.3e-96 S Domain of unknown function DUF87
MMAEJEDM_00351 4.1e-229 V ABC transporter transmembrane region
MMAEJEDM_00352 4e-216 XK27_09600 V ABC transporter, ATP-binding protein
MMAEJEDM_00353 9.3e-32 K Transcriptional regulator, MarR family
MMAEJEDM_00354 4.9e-172 S Putative peptidoglycan binding domain
MMAEJEDM_00356 2.1e-24 relB L RelB antitoxin
MMAEJEDM_00357 1.4e-61 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MMAEJEDM_00358 2.3e-140 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
MMAEJEDM_00359 1.7e-178 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MMAEJEDM_00360 8.6e-109 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MMAEJEDM_00361 6e-223 pepF E Oligopeptidase F
MMAEJEDM_00362 3.7e-96 yicL EG EamA-like transporter family
MMAEJEDM_00363 8.8e-50 yugI 5.3.1.9 J general stress protein
MMAEJEDM_00364 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MMAEJEDM_00365 8.8e-92 dedA S SNARE associated Golgi protein
MMAEJEDM_00366 4.6e-32 S Protein of unknown function (DUF1461)
MMAEJEDM_00367 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MMAEJEDM_00368 1.9e-53 yutD S Protein of unknown function (DUF1027)
MMAEJEDM_00369 6.6e-57 S Calcineurin-like phosphoesterase
MMAEJEDM_00370 2.3e-182 cycA E Amino acid permease
MMAEJEDM_00371 6.4e-97 ytxK 2.1.1.72 L N-6 DNA Methylase
MMAEJEDM_00373 4.1e-11 S Putative Competence protein ComGF
MMAEJEDM_00375 1.5e-13
MMAEJEDM_00376 7.9e-27 comGC U competence protein ComGC
MMAEJEDM_00377 1.6e-58 comGB NU type II secretion system
MMAEJEDM_00378 3.7e-120 L ISXO2-like transposase domain
MMAEJEDM_00380 7.4e-23 3.1.21.3 V N-6 DNA Methylase
MMAEJEDM_00381 3.9e-104 3.1.21.3 L N-6 DNA Methylase
MMAEJEDM_00382 7.8e-27 comGB NU type II secretion system
MMAEJEDM_00383 2.3e-120 comGA NU Type II IV secretion system protein
MMAEJEDM_00384 1e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MMAEJEDM_00385 4.3e-119 yebC K Transcriptional regulatory protein
MMAEJEDM_00386 3.7e-42 S VanZ like family
MMAEJEDM_00387 1.3e-158 ccpA K catabolite control protein A
MMAEJEDM_00388 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MMAEJEDM_00389 3e-14
MMAEJEDM_00392 4.5e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MMAEJEDM_00393 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
MMAEJEDM_00394 2.3e-65 hly S protein, hemolysin III
MMAEJEDM_00395 2.8e-40 M1-874 K Domain of unknown function (DUF1836)
MMAEJEDM_00396 9.4e-84 S membrane
MMAEJEDM_00397 1.1e-79 S VIT family
MMAEJEDM_00398 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MMAEJEDM_00399 2.7e-56 P Plays a role in the regulation of phosphate uptake
MMAEJEDM_00400 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MMAEJEDM_00401 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MMAEJEDM_00402 3e-122 pstA P Phosphate transport system permease protein PstA
MMAEJEDM_00403 5.4e-119 pstC P probably responsible for the translocation of the substrate across the membrane
MMAEJEDM_00404 1.4e-97 pstS P Phosphate
MMAEJEDM_00405 3.9e-41 yjbH Q Thioredoxin
MMAEJEDM_00406 1.3e-231 pepF E oligoendopeptidase F
MMAEJEDM_00407 1.2e-67 coiA 3.6.4.12 S Competence protein
MMAEJEDM_00408 9.2e-48 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MMAEJEDM_00409 9.1e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MMAEJEDM_00411 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MMAEJEDM_00412 5.6e-127
MMAEJEDM_00413 5.1e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MMAEJEDM_00414 1.6e-42 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
MMAEJEDM_00415 2.3e-31 K Transcriptional regulator
MMAEJEDM_00416 2e-104 ybhR V ABC transporter
MMAEJEDM_00417 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
MMAEJEDM_00418 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MMAEJEDM_00419 8.8e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MMAEJEDM_00420 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MMAEJEDM_00421 2.2e-270 helD 3.6.4.12 L DNA helicase
MMAEJEDM_00423 1.3e-114 htpX O Belongs to the peptidase M48B family
MMAEJEDM_00424 8.7e-72 lemA S LemA family
MMAEJEDM_00425 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
MMAEJEDM_00426 3.2e-45 yjcF K protein acetylation
MMAEJEDM_00428 3.9e-254 yfiC V ABC transporter
MMAEJEDM_00429 9.9e-223 lmrA V ABC transporter, ATP-binding protein
MMAEJEDM_00430 5.8e-35 K Bacterial regulatory proteins, tetR family
MMAEJEDM_00431 9.5e-246 yhcA V ABC transporter, ATP-binding protein
MMAEJEDM_00432 2.6e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MMAEJEDM_00433 1e-146 G Transporter, major facilitator family protein
MMAEJEDM_00434 5.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
MMAEJEDM_00435 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
MMAEJEDM_00436 2.5e-113 K response regulator
MMAEJEDM_00437 3.4e-89 patB 4.4.1.8 E Aminotransferase, class I
MMAEJEDM_00438 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MMAEJEDM_00439 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MMAEJEDM_00440 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MMAEJEDM_00441 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MMAEJEDM_00442 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
MMAEJEDM_00443 4.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
MMAEJEDM_00444 2.4e-164 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MMAEJEDM_00445 1.1e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MMAEJEDM_00446 3.5e-70 mltD CBM50 M NlpC P60 family protein
MMAEJEDM_00447 1.8e-52 manO S Domain of unknown function (DUF956)
MMAEJEDM_00448 2.1e-147 manN G system, mannose fructose sorbose family IID component
MMAEJEDM_00449 6.4e-116 manY G PTS system sorbose-specific iic component
MMAEJEDM_00450 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MMAEJEDM_00451 4.1e-80 rbsB G sugar-binding domain protein
MMAEJEDM_00452 5.1e-99 baeS T Histidine kinase
MMAEJEDM_00453 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
MMAEJEDM_00454 1.8e-120 G Bacterial extracellular solute-binding protein
MMAEJEDM_00455 9.1e-71 S Protein of unknown function (DUF554)
MMAEJEDM_00456 1e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MMAEJEDM_00457 1.9e-32 merR K MerR HTH family regulatory protein
MMAEJEDM_00458 2.1e-197 lmrB EGP Major facilitator Superfamily
MMAEJEDM_00459 7e-34 S Domain of unknown function (DUF4811)
MMAEJEDM_00460 4.3e-41 S CAAX protease self-immunity
MMAEJEDM_00461 8.5e-60 yceE S haloacid dehalogenase-like hydrolase
MMAEJEDM_00462 7.6e-74 glcR K DeoR C terminal sensor domain
MMAEJEDM_00463 1.3e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MMAEJEDM_00464 1.3e-183 lmrB EGP Major facilitator Superfamily
MMAEJEDM_00465 2.7e-54 bioY S BioY family
MMAEJEDM_00466 1.2e-93 S Predicted membrane protein (DUF2207)
MMAEJEDM_00467 1.4e-19
MMAEJEDM_00468 2.8e-36 M Glycosyltransferase group 2 family protein
MMAEJEDM_00469 7.4e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MMAEJEDM_00470 2.8e-58 ktrA P TrkA-N domain
MMAEJEDM_00471 1.2e-114 ntpJ P Potassium uptake protein
MMAEJEDM_00472 5.3e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MMAEJEDM_00473 1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
MMAEJEDM_00474 3.5e-216 scrB 3.2.1.26 GH32 G invertase
MMAEJEDM_00475 1.7e-147 scrR K helix_turn _helix lactose operon repressor
MMAEJEDM_00476 1.4e-74 G Peptidase_C39 like family
MMAEJEDM_00478 7.7e-140 2.1.1.72, 3.1.21.3 V N-6 DNA Methylase
MMAEJEDM_00479 1.5e-43 S zinc-ribbon domain
MMAEJEDM_00480 3.3e-311 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MMAEJEDM_00481 9.5e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MMAEJEDM_00482 8.1e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MMAEJEDM_00483 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
MMAEJEDM_00484 5.4e-157 XK27_09615 S reductase
MMAEJEDM_00485 1.2e-39 2.7.7.65 T phosphorelay sensor kinase activity
MMAEJEDM_00486 1.2e-148 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MMAEJEDM_00487 4.1e-41 cps3I G Acyltransferase family
MMAEJEDM_00488 3.6e-14
MMAEJEDM_00489 1.4e-127 S Bacterial membrane protein YfhO
MMAEJEDM_00490 3.9e-163 XK27_08315 M Sulfatase
MMAEJEDM_00491 5.3e-70 M Domain of unknown function (DUF4422)
MMAEJEDM_00492 4.7e-59 cps3F
MMAEJEDM_00493 3.7e-87 waaB GT4 M Glycosyl transferases group 1
MMAEJEDM_00494 2.8e-62 S Psort location CytoplasmicMembrane, score
MMAEJEDM_00495 9.7e-75 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MMAEJEDM_00496 8.3e-178 thrC 4.2.3.1 E Threonine synthase
MMAEJEDM_00497 4.5e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MMAEJEDM_00498 8.8e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MMAEJEDM_00499 4.3e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MMAEJEDM_00502 1e-09 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MMAEJEDM_00505 9.3e-12 tetR K transcriptional regulator
MMAEJEDM_00506 4.1e-15 tetR K transcriptional regulator
MMAEJEDM_00508 1.2e-41 wecD K Acetyltransferase GNAT Family
MMAEJEDM_00509 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
MMAEJEDM_00510 1.1e-70 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MMAEJEDM_00511 5.6e-08 S SdpI/YhfL protein family
MMAEJEDM_00512 2.2e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
MMAEJEDM_00513 3.1e-286 pepO 3.4.24.71 O Peptidase family M13
MMAEJEDM_00514 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
MMAEJEDM_00515 9.1e-54 K Transcriptional regulator C-terminal region
MMAEJEDM_00516 1.6e-55 jag S R3H domain protein
MMAEJEDM_00517 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
MMAEJEDM_00518 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
MMAEJEDM_00519 5.1e-77 azlC E branched-chain amino acid
MMAEJEDM_00520 2.7e-58 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MMAEJEDM_00521 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MMAEJEDM_00522 9.7e-91 licT K CAT RNA binding domain
MMAEJEDM_00523 6.9e-214 G phosphotransferase system
MMAEJEDM_00524 1.2e-221 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MMAEJEDM_00525 1.4e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
MMAEJEDM_00526 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
MMAEJEDM_00527 1.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
MMAEJEDM_00528 4.1e-75 XK27_02070 S Nitroreductase family
MMAEJEDM_00529 1.7e-111 endA F DNA RNA non-specific endonuclease
MMAEJEDM_00531 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
MMAEJEDM_00532 1.7e-61 K Bacterial regulatory proteins, tetR family
MMAEJEDM_00533 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MMAEJEDM_00534 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MMAEJEDM_00535 5.6e-69 dhaL 2.7.1.121 S Dak2
MMAEJEDM_00536 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
MMAEJEDM_00537 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MMAEJEDM_00538 4.9e-176 yjcE P Sodium proton antiporter
MMAEJEDM_00539 7.5e-209 mtlR K Mga helix-turn-helix domain
MMAEJEDM_00540 1e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MMAEJEDM_00541 1e-187 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MMAEJEDM_00542 2.5e-44 M Glycosyl hydrolases family 25
MMAEJEDM_00544 4.5e-102 tcyB E ABC transporter
MMAEJEDM_00545 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MMAEJEDM_00546 2e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MMAEJEDM_00547 1.6e-38 K Transcriptional regulator
MMAEJEDM_00548 2.2e-107 terC P Integral membrane protein TerC family
MMAEJEDM_00549 1.1e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MMAEJEDM_00550 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMAEJEDM_00551 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MMAEJEDM_00552 1.1e-41 gntR1 K Transcriptional regulator, GntR family
MMAEJEDM_00553 6.1e-96 V ABC transporter, ATP-binding protein
MMAEJEDM_00554 2.5e-08
MMAEJEDM_00555 1.1e-39 ybjQ S Belongs to the UPF0145 family
MMAEJEDM_00556 4e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
MMAEJEDM_00557 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MMAEJEDM_00558 6.1e-158 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MMAEJEDM_00559 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MMAEJEDM_00560 1.1e-33
MMAEJEDM_00561 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MMAEJEDM_00562 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MMAEJEDM_00563 8e-64 srtA 3.4.22.70 M sortase family
MMAEJEDM_00565 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MMAEJEDM_00566 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
MMAEJEDM_00567 1.7e-184 L Probable transposase
MMAEJEDM_00568 0.0 pacL 3.6.3.8 P P-type ATPase
MMAEJEDM_00569 6.4e-110 3.1.4.46 C phosphodiesterase
MMAEJEDM_00570 4.5e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MMAEJEDM_00571 4.7e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MMAEJEDM_00572 2.8e-82 noc K Belongs to the ParB family
MMAEJEDM_00573 6.5e-118 soj D Sporulation initiation inhibitor
MMAEJEDM_00574 4.1e-108 spo0J K Belongs to the ParB family
MMAEJEDM_00575 9e-24 yyzM S Bacterial protein of unknown function (DUF951)
MMAEJEDM_00576 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MMAEJEDM_00577 1.9e-53 XK27_01040 S Protein of unknown function (DUF1129)
MMAEJEDM_00578 1.4e-94 S Bacterial membrane protein, YfhO
MMAEJEDM_00579 1.4e-49 I Alpha/beta hydrolase family
MMAEJEDM_00580 7.3e-14 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MMAEJEDM_00581 1.5e-38
MMAEJEDM_00582 2.7e-104 psaA P Belongs to the bacterial solute-binding protein 9 family
MMAEJEDM_00583 1e-98 fhuC P ABC transporter
MMAEJEDM_00584 2.1e-103 znuB U ABC 3 transport family
MMAEJEDM_00585 1.5e-55 S ECF transporter, substrate-specific component
MMAEJEDM_00586 4.7e-103 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MMAEJEDM_00587 1.9e-88 S NADPH-dependent FMN reductase
MMAEJEDM_00588 1.2e-27 K helix_turn_helix, mercury resistance
MMAEJEDM_00589 1.2e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MMAEJEDM_00591 2.6e-154 EGP Major facilitator Superfamily
MMAEJEDM_00592 3.9e-58 S Haloacid dehalogenase-like hydrolase
MMAEJEDM_00593 1.6e-88 yvyE 3.4.13.9 S YigZ family
MMAEJEDM_00594 9.5e-38 S CAAX protease self-immunity
MMAEJEDM_00595 5.8e-117 cps1D M Domain of unknown function (DUF4422)
MMAEJEDM_00596 8.6e-62 S Glycosyltransferase like family 2
MMAEJEDM_00597 3.6e-141 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MMAEJEDM_00598 9.4e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MMAEJEDM_00599 6.8e-179 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MMAEJEDM_00600 3.6e-130 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MMAEJEDM_00601 3.6e-117 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
MMAEJEDM_00602 4.4e-27 S zinc-ribbon domain
MMAEJEDM_00603 2.5e-83 S response to antibiotic
MMAEJEDM_00604 7.5e-98 M Glycosyl transferase family 8
MMAEJEDM_00605 4.1e-38 M group 2 family protein
MMAEJEDM_00606 3.3e-90
MMAEJEDM_00607 4.5e-28 M Glycosyltransferase like family 2
MMAEJEDM_00609 1.5e-67 S Polysaccharide pyruvyl transferase
MMAEJEDM_00610 5.5e-115 cps2J S Polysaccharide biosynthesis protein
MMAEJEDM_00612 1.7e-73 epsB M biosynthesis protein
MMAEJEDM_00613 5.9e-82 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MMAEJEDM_00614 2.1e-111 ywqE 3.1.3.48 GM PHP domain protein
MMAEJEDM_00615 2.6e-124 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MMAEJEDM_00616 9.1e-92 rfbP M Bacterial sugar transferase
MMAEJEDM_00617 1.7e-117 M Core-2/I-Branching enzyme
MMAEJEDM_00618 2.1e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
MMAEJEDM_00619 3.8e-188 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
MMAEJEDM_00620 1.1e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MMAEJEDM_00621 4.2e-58 radC L DNA repair protein
MMAEJEDM_00622 2.7e-202 intIA L similarity to EGAD 7942
MMAEJEDM_00623 0.0 L similarity to EGAD 8390
MMAEJEDM_00624 1.9e-57 S similarity to EGAD 6135
MMAEJEDM_00625 3.2e-144 ant 2.7.7.47 S Domain of unknown function (DUF4111)
MMAEJEDM_00626 2e-105 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
MMAEJEDM_00627 3.1e-124 ubiE_2 Q Thiopurine S-methyltransferase (TPMT)
MMAEJEDM_00628 4.5e-21 K Cold shock
MMAEJEDM_00629 1.8e-155 mreB D cell shape determining protein MreB
MMAEJEDM_00630 2.1e-88 mreC M Involved in formation and maintenance of cell shape
MMAEJEDM_00631 8.9e-55 mreD M rod shape-determining protein MreD
MMAEJEDM_00632 1.4e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MMAEJEDM_00633 1.8e-126 minD D Belongs to the ParA family
MMAEJEDM_00634 1.8e-92 glnP P ABC transporter permease
MMAEJEDM_00635 1.1e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MMAEJEDM_00636 2.4e-108 aatB ET ABC transporter substrate-binding protein
MMAEJEDM_00637 6.3e-99 D Alpha beta
MMAEJEDM_00638 2.7e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MMAEJEDM_00639 3.4e-08 S Protein of unknown function (DUF3397)
MMAEJEDM_00640 5.2e-64 mraZ K Belongs to the MraZ family
MMAEJEDM_00641 8.8e-141 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MMAEJEDM_00642 2.5e-11 ftsL D cell division protein FtsL
MMAEJEDM_00643 2.4e-279 ftsI 3.4.16.4 M Penicillin-binding Protein
MMAEJEDM_00644 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MMAEJEDM_00645 2e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MMAEJEDM_00646 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MMAEJEDM_00647 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MMAEJEDM_00648 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MMAEJEDM_00649 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MMAEJEDM_00650 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MMAEJEDM_00651 3e-19 yggT S YGGT family
MMAEJEDM_00652 4.5e-82 ylmH S S4 domain protein
MMAEJEDM_00653 8.6e-62 divIVA D DivIVA domain protein
MMAEJEDM_00654 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MMAEJEDM_00655 1.3e-84 3.1.21.3 V Type I restriction modification DNA specificity domain
MMAEJEDM_00656 6.1e-131 L Belongs to the 'phage' integrase family
MMAEJEDM_00657 4.4e-63 hsdS_1 3.1.21.3 V Type I Restriction
MMAEJEDM_00658 2.3e-63 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
MMAEJEDM_00659 8.8e-202 hsdM 2.1.1.72 V type I restriction-modification system
MMAEJEDM_00660 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MMAEJEDM_00662 3e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
MMAEJEDM_00663 5.7e-57 3.6.1.27 I Acid phosphatase homologues
MMAEJEDM_00664 1.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
MMAEJEDM_00665 6.3e-73 2.3.1.178 M GNAT acetyltransferase
MMAEJEDM_00667 2.9e-198 ade 3.5.4.2 F Adenine deaminase C-terminal domain
MMAEJEDM_00668 7.8e-65 ypsA S Belongs to the UPF0398 family
MMAEJEDM_00669 3.7e-188 nhaC C Na H antiporter NhaC
MMAEJEDM_00670 2.3e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MMAEJEDM_00671 2.1e-292 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MMAEJEDM_00672 3.6e-112 xerD D recombinase XerD
MMAEJEDM_00673 4.8e-125 cvfB S S1 domain
MMAEJEDM_00674 4.1e-51 yeaL S Protein of unknown function (DUF441)
MMAEJEDM_00675 3.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MMAEJEDM_00676 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MMAEJEDM_00677 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MMAEJEDM_00678 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MMAEJEDM_00679 3.5e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MMAEJEDM_00680 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MMAEJEDM_00681 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MMAEJEDM_00682 7.9e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MMAEJEDM_00683 2.5e-177 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MMAEJEDM_00684 1.5e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MMAEJEDM_00685 3.1e-71
MMAEJEDM_00687 3.7e-12
MMAEJEDM_00688 9.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MMAEJEDM_00689 5.5e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
MMAEJEDM_00690 1.8e-231 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MMAEJEDM_00691 3.6e-17 yneR
MMAEJEDM_00692 4.8e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MMAEJEDM_00693 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MMAEJEDM_00694 1.8e-53 yiiE S Protein of unknown function (DUF1211)
MMAEJEDM_00695 0.0 asnB 6.3.5.4 E Asparagine synthase
MMAEJEDM_00696 7.4e-64 D peptidase
MMAEJEDM_00697 1.6e-116 S Glycosyl transferase family 2
MMAEJEDM_00698 1.9e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MMAEJEDM_00699 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MMAEJEDM_00700 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MMAEJEDM_00701 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
MMAEJEDM_00702 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MMAEJEDM_00703 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MMAEJEDM_00704 8.4e-154 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MMAEJEDM_00705 9e-20 yaaA S S4 domain protein YaaA
MMAEJEDM_00706 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MMAEJEDM_00707 6.2e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MMAEJEDM_00708 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MMAEJEDM_00709 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MMAEJEDM_00710 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MMAEJEDM_00711 1.1e-199 nupG F Nucleoside
MMAEJEDM_00712 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
MMAEJEDM_00713 1.7e-53 K LysR substrate binding domain
MMAEJEDM_00714 1.8e-07
MMAEJEDM_00715 1.8e-65 yxkH G Polysaccharide deacetylase
MMAEJEDM_00716 9e-30 yqkB S Belongs to the HesB IscA family
MMAEJEDM_00717 2.8e-28 L HTH-like domain
MMAEJEDM_00718 2.2e-53 L PFAM Integrase catalytic region
MMAEJEDM_00719 1.1e-59 uspA T Universal stress protein family
MMAEJEDM_00720 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
MMAEJEDM_00721 1.1e-25
MMAEJEDM_00722 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MMAEJEDM_00723 5.7e-108 puuD S peptidase C26
MMAEJEDM_00724 6.8e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MMAEJEDM_00725 7e-153 lsa S ABC transporter
MMAEJEDM_00726 4.7e-148 mepA V MATE efflux family protein
MMAEJEDM_00727 2.2e-39 arbx M family 8
MMAEJEDM_00729 2.4e-31 M Glycosyltransferase like family 2
MMAEJEDM_00730 5.1e-70 nss M transferase activity, transferring glycosyl groups
MMAEJEDM_00731 1.6e-38 M Glycosyl transferase family 8
MMAEJEDM_00732 1.2e-55 nss M transferase activity, transferring glycosyl groups
MMAEJEDM_00734 7.6e-15 arbx M family 8
MMAEJEDM_00735 1.7e-08 M Glycosyltransferase like family 2
MMAEJEDM_00736 2e-66 nss M transferase activity, transferring glycosyl groups
MMAEJEDM_00737 1.3e-108 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MMAEJEDM_00738 9e-34 yxaB 2.4.1.166 GT2 M Glycosyltransferase like family 2
MMAEJEDM_00739 1.3e-151 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MMAEJEDM_00740 2.4e-55 L Helix-turn-helix domain
MMAEJEDM_00741 6.6e-81 L hmm pf00665
MMAEJEDM_00743 8.8e-24 3.2.1.18 GH33 M Rib/alpha-like repeat
MMAEJEDM_00744 4.6e-247 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
MMAEJEDM_00745 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MMAEJEDM_00746 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MMAEJEDM_00747 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MMAEJEDM_00748 5.7e-71 ywlG S Belongs to the UPF0340 family
MMAEJEDM_00749 1.3e-63 S Acetyltransferase (GNAT) domain
MMAEJEDM_00750 2.4e-30 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MMAEJEDM_00751 9.4e-31 yjaB_1 K Acetyltransferase (GNAT) domain
MMAEJEDM_00752 3.2e-12 Z012_01675 S Hydrolases of the alpha beta superfamily
MMAEJEDM_00753 5.7e-09
MMAEJEDM_00754 6.2e-164 mcrC V Psort location Cytoplasmic, score
MMAEJEDM_00755 0.0 mcrB 2.1.1.72 V ATPase family associated with various cellular activities (AAA)
MMAEJEDM_00756 3.3e-18
MMAEJEDM_00757 2.1e-212 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MMAEJEDM_00758 9.8e-146 yegS 2.7.1.107 G Lipid kinase
MMAEJEDM_00759 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MMAEJEDM_00760 6.8e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MMAEJEDM_00761 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MMAEJEDM_00762 2.1e-160 camS S sex pheromone
MMAEJEDM_00763 6.6e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MMAEJEDM_00764 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MMAEJEDM_00766 6e-144 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MMAEJEDM_00769 1.1e-14 S Phage tail assembly chaperone protein, TAC
MMAEJEDM_00770 4e-47
MMAEJEDM_00771 1.1e-18
MMAEJEDM_00772 4.5e-32
MMAEJEDM_00773 5.8e-12
MMAEJEDM_00774 3.2e-35 S Phage gp6-like head-tail connector protein
MMAEJEDM_00775 1.9e-104 gpG
MMAEJEDM_00776 1.7e-12 S Domain of unknown function (DUF4355)
MMAEJEDM_00777 1.8e-61 S Phage Mu protein F like protein
MMAEJEDM_00778 3.9e-163 S Phage portal protein, SPP1 Gp6-like
MMAEJEDM_00779 3.1e-133 ps334 S Terminase-like family
MMAEJEDM_00780 6.4e-42 L transposase activity
MMAEJEDM_00781 1.5e-22 speH 2.5.1.16, 4.1.1.50 E S-adenosylmethionine decarboxylase
MMAEJEDM_00782 1.8e-96 2.1.1.72 L Psort location Cytoplasmic, score
MMAEJEDM_00783 3.1e-32 arpU S Phage transcriptional regulator, ArpU family
MMAEJEDM_00790 1.8e-62 Q DNA (cytosine-5-)-methyltransferase activity
MMAEJEDM_00793 9.8e-73 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MMAEJEDM_00794 2.8e-14 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MMAEJEDM_00795 1.7e-30 rusA L Endodeoxyribonuclease RusA
MMAEJEDM_00798 6.5e-31 dnaC L IstB-like ATP binding protein
MMAEJEDM_00800 9e-25 L Helix-turn-helix domain
MMAEJEDM_00801 1.4e-11 K Cro/C1-type HTH DNA-binding domain
MMAEJEDM_00803 2.2e-18
MMAEJEDM_00804 2.3e-63 S Putative HNHc nuclease
MMAEJEDM_00805 1.2e-38 S ERF superfamily
MMAEJEDM_00806 6.4e-08 S Bacteriophage Mu Gam like protein
MMAEJEDM_00809 3.4e-19
MMAEJEDM_00810 4e-48 S DNA binding
MMAEJEDM_00811 3.3e-16 K Cro/C1-type HTH DNA-binding domain
MMAEJEDM_00814 4.9e-13
MMAEJEDM_00815 4e-33 K Transcriptional regulator, HxlR family
MMAEJEDM_00816 2.5e-170 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MMAEJEDM_00817 1.3e-102 ydhQ K UbiC transcription regulator-associated domain protein
MMAEJEDM_00818 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MMAEJEDM_00819 1.8e-82 pncA Q isochorismatase
MMAEJEDM_00820 7.1e-64 3.1.3.73 G phosphoglycerate mutase
MMAEJEDM_00821 7.3e-259 treB G phosphotransferase system
MMAEJEDM_00822 7.5e-84 treR K UTRA
MMAEJEDM_00823 1.4e-250 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MMAEJEDM_00824 1.9e-167 mdtG EGP Major facilitator Superfamily
MMAEJEDM_00827 1.4e-192 XK27_08315 M Sulfatase
MMAEJEDM_00828 5.8e-58 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MMAEJEDM_00829 6.4e-48 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MMAEJEDM_00830 7.6e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MMAEJEDM_00831 1.3e-133 coaA 2.7.1.33 F Pantothenic acid kinase
MMAEJEDM_00832 2.2e-44 E GDSL-like Lipase/Acylhydrolase
MMAEJEDM_00833 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MMAEJEDM_00834 5.6e-190 glnPH2 P ABC transporter permease
MMAEJEDM_00836 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MMAEJEDM_00837 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MMAEJEDM_00838 5.9e-274 dnaK O Heat shock 70 kDa protein
MMAEJEDM_00839 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MMAEJEDM_00840 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MMAEJEDM_00841 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MMAEJEDM_00842 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MMAEJEDM_00843 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MMAEJEDM_00844 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MMAEJEDM_00845 6.9e-26 ylxQ J ribosomal protein
MMAEJEDM_00846 1.4e-39 ylxR K Protein of unknown function (DUF448)
MMAEJEDM_00847 4.8e-170 nusA K Participates in both transcription termination and antitermination
MMAEJEDM_00848 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
MMAEJEDM_00849 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MMAEJEDM_00850 1.7e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MMAEJEDM_00851 9.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MMAEJEDM_00852 4.4e-101 cdsA 2.7.7.41 S Belongs to the CDS family
MMAEJEDM_00853 4.9e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MMAEJEDM_00854 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MMAEJEDM_00855 1.4e-114 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MMAEJEDM_00856 2.7e-48 S Domain of unknown function (DUF956)
MMAEJEDM_00857 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MMAEJEDM_00859 1e-78 2.4.2.3 F Phosphorylase superfamily
MMAEJEDM_00860 1.4e-290 ybiT S ABC transporter, ATP-binding protein
MMAEJEDM_00861 1.5e-62 bCE_4747 S Beta-lactamase superfamily domain
MMAEJEDM_00862 1.3e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MMAEJEDM_00863 3.4e-68 S overlaps another CDS with the same product name
MMAEJEDM_00864 7.5e-39 S overlaps another CDS with the same product name
MMAEJEDM_00865 2.9e-86 S overlaps another CDS with the same product name
MMAEJEDM_00867 6e-57 spoVK O ATPase family associated with various cellular activities (AAA)
MMAEJEDM_00868 3.6e-24 L Eco57I restriction-modification methylase
MMAEJEDM_00869 1.4e-70 L recombinase activity
MMAEJEDM_00870 4.1e-73
MMAEJEDM_00871 2.8e-22
MMAEJEDM_00872 1.2e-70 ydcZ S Putative inner membrane exporter, YdcZ
MMAEJEDM_00873 1.7e-87 S hydrolase
MMAEJEDM_00874 2.5e-205 ywfO S HD domain protein
MMAEJEDM_00875 4.4e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
MMAEJEDM_00876 1.8e-32 ywiB S Domain of unknown function (DUF1934)
MMAEJEDM_00877 9.9e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MMAEJEDM_00878 3.3e-289 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MMAEJEDM_00881 1.6e-201 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MMAEJEDM_00882 4.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MMAEJEDM_00883 1.4e-40 rpmE2 J Ribosomal protein L31
MMAEJEDM_00884 8e-61
MMAEJEDM_00886 1.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MMAEJEDM_00887 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MMAEJEDM_00888 5.1e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MMAEJEDM_00889 2e-10 EGP Transmembrane secretion effector
MMAEJEDM_00890 1e-28 EGP Transmembrane secretion effector
MMAEJEDM_00891 5.2e-137 purR 2.4.2.7 F pur operon repressor
MMAEJEDM_00892 2.5e-44 adhR K helix_turn_helix, mercury resistance
MMAEJEDM_00893 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MMAEJEDM_00895 1.2e-103 pfoS S Phosphotransferase system, EIIC
MMAEJEDM_00896 2.9e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MMAEJEDM_00897 2.9e-149 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MMAEJEDM_00898 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MMAEJEDM_00899 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
MMAEJEDM_00900 3e-155 amtB P ammonium transporter
MMAEJEDM_00901 9e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MMAEJEDM_00902 6.6e-46 argR K Regulates arginine biosynthesis genes
MMAEJEDM_00903 1.7e-138 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
MMAEJEDM_00904 8.3e-90 S Alpha/beta hydrolase of unknown function (DUF915)
MMAEJEDM_00905 1.2e-22 veg S Biofilm formation stimulator VEG
MMAEJEDM_00906 7e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MMAEJEDM_00907 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MMAEJEDM_00908 9.2e-104 tatD L hydrolase, TatD family
MMAEJEDM_00909 6.5e-55 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MMAEJEDM_00910 3.9e-146 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MMAEJEDM_00911 2.3e-38 S Replication initiator protein A (RepA) N-terminus
MMAEJEDM_00912 3.2e-109 L Initiator Replication protein
MMAEJEDM_00914 3.7e-54 L PLD-like domain
MMAEJEDM_00915 6.1e-53 L PLD-like domain
MMAEJEDM_00916 3.7e-17 S Protein of unknown function (DUF805)
MMAEJEDM_00917 4.7e-226 tetP J elongation factor G
MMAEJEDM_00918 1.2e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MMAEJEDM_00920 1.8e-217 yjeM E Amino Acid
MMAEJEDM_00921 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
MMAEJEDM_00922 4.3e-75 K Helix-turn-helix domain, rpiR family
MMAEJEDM_00923 3.3e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MMAEJEDM_00924 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MMAEJEDM_00925 2.9e-90 nanK GK ROK family
MMAEJEDM_00926 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
MMAEJEDM_00927 1.4e-64 G Xylose isomerase domain protein TIM barrel
MMAEJEDM_00928 6.6e-154 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MMAEJEDM_00929 1.1e-206 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MMAEJEDM_00930 2.1e-72 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MMAEJEDM_00931 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MMAEJEDM_00932 5.9e-41 S Iron-sulfur cluster assembly protein
MMAEJEDM_00933 3.4e-67 S Protein of unknown function (DUF1440)
MMAEJEDM_00934 1e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MMAEJEDM_00935 2.7e-187 mtnE 2.6.1.83 E Aminotransferase
MMAEJEDM_00936 4.5e-16 S Phage Mu protein F like protein
MMAEJEDM_00937 1.1e-26 S Phage Mu protein F like protein
MMAEJEDM_00939 4.3e-58 tlpA2 L Transposase IS200 like
MMAEJEDM_00940 3e-160 L transposase, IS605 OrfB family
MMAEJEDM_00942 1.3e-06 S Domain of unknown function (DUF4355)
MMAEJEDM_00943 2e-97
MMAEJEDM_00944 1.4e-28 S Phage gp6-like head-tail connector protein
MMAEJEDM_00946 2.3e-14
MMAEJEDM_00947 2.2e-10 blpT
MMAEJEDM_00948 2.4e-70 xerD L Phage integrase, N-terminal SAM-like domain
MMAEJEDM_00949 2.4e-265 fbp 3.1.3.11 G phosphatase activity
MMAEJEDM_00951 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MMAEJEDM_00952 7.9e-99 fabK 1.3.1.9 S Nitronate monooxygenase
MMAEJEDM_00953 1.2e-25 S Phage minor capsid protein 2
MMAEJEDM_00959 4.3e-07
MMAEJEDM_00961 3e-48 M Phage tail tape measure protein TP901
MMAEJEDM_00962 4e-110 IQ NAD dependent epimerase/dehydratase family
MMAEJEDM_00963 1.5e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
MMAEJEDM_00964 4.5e-43 gutM K Glucitol operon activator protein (GutM)
MMAEJEDM_00965 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
MMAEJEDM_00966 4.2e-136 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
MMAEJEDM_00967 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MMAEJEDM_00968 4.3e-65 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
MMAEJEDM_00969 7.2e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MMAEJEDM_00970 7.3e-136 pfoS S Phosphotransferase system, EIIC
MMAEJEDM_00971 2.9e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
MMAEJEDM_00972 1.9e-59 hsdM 2.1.1.72 V HsdM N-terminal domain
MMAEJEDM_00973 4.9e-250 2.1.1.72 V type I restriction-modification system
MMAEJEDM_00974 7.1e-45 3.1.21.3 L Restriction modification system DNA specificity domain
MMAEJEDM_00975 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MMAEJEDM_00976 1.1e-27 K Helix-turn-helix XRE-family like proteins
MMAEJEDM_00977 2.3e-141 yfeO P Voltage gated chloride channel
MMAEJEDM_00978 1.2e-225 E ABC transporter, substratebinding protein
MMAEJEDM_00979 8.1e-116 sufC O FeS assembly ATPase SufC
MMAEJEDM_00980 6e-145 sufD O FeS assembly protein SufD
MMAEJEDM_00981 3.1e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MMAEJEDM_00982 3.2e-40 nifU C SUF system FeS assembly protein, NifU family
MMAEJEDM_00983 4.2e-240 sufB O assembly protein SufB
MMAEJEDM_00984 1.5e-45 S VIT family
MMAEJEDM_00985 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MMAEJEDM_00986 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MMAEJEDM_00987 1.6e-112 rssA S Phospholipase, patatin family
MMAEJEDM_00988 6.3e-16
MMAEJEDM_00990 5.7e-39
MMAEJEDM_00991 1e-197 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
MMAEJEDM_00995 1.2e-87 S Fic/DOC family
MMAEJEDM_00996 6.6e-11 S sequence-specific DNA binding
MMAEJEDM_00997 2.3e-11 3.4.21.88 K Peptidase S24-like
MMAEJEDM_01008 1.1e-09 S Psort location Cytoplasmic, score
MMAEJEDM_01010 2.2e-20 S Replication initiator protein A (RepA) N-terminus
MMAEJEDM_01015 1.8e-06
MMAEJEDM_01018 2.2e-23 K SIR2-like domain
MMAEJEDM_01020 7.5e-20
MMAEJEDM_01021 3.8e-12 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
MMAEJEDM_01025 2.3e-61 ruvB 3.6.4.12 L four-way junction helicase activity
MMAEJEDM_01026 4.8e-43 gepA S Protein of unknown function (DUF4065)
MMAEJEDM_01027 8.6e-34
MMAEJEDM_01028 3.3e-12 chpR T PFAM SpoVT AbrB
MMAEJEDM_01029 4.4e-29 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MMAEJEDM_01030 7.4e-79 S Fic/DOC family
MMAEJEDM_01031 4.2e-206 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction-modification system methyltransferase subunit
MMAEJEDM_01033 1.3e-25 D nuclear chromosome segregation
MMAEJEDM_01034 3.7e-07
MMAEJEDM_01035 5.3e-106 L Belongs to the 'phage' integrase family
MMAEJEDM_01042 5.1e-08
MMAEJEDM_01048 1.4e-06
MMAEJEDM_01049 8.8e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MMAEJEDM_01050 1.7e-54 rplI J Binds to the 23S rRNA
MMAEJEDM_01051 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MMAEJEDM_01052 1.2e-63 C FMN binding
MMAEJEDM_01053 2.8e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MMAEJEDM_01055 3.9e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MMAEJEDM_01056 1.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
MMAEJEDM_01057 2.1e-12 S CAAX protease self-immunity
MMAEJEDM_01058 1.2e-81 S Belongs to the UPF0246 family
MMAEJEDM_01059 2.3e-90 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MMAEJEDM_01060 1.6e-128 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
MMAEJEDM_01061 8.9e-76 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MMAEJEDM_01062 3.1e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MMAEJEDM_01063 1.2e-159 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MMAEJEDM_01064 3.7e-56 3.1.3.48 K Transcriptional regulator
MMAEJEDM_01065 4.6e-180 1.3.5.4 C FMN_bind
MMAEJEDM_01066 7e-200 L transposition, DNA-mediated
MMAEJEDM_01067 1.7e-46 K Acetyltransferase (GNAT) domain
MMAEJEDM_01068 1.4e-154 oppF P Belongs to the ABC transporter superfamily
MMAEJEDM_01069 1.3e-180 oppD P Belongs to the ABC transporter superfamily
MMAEJEDM_01070 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMAEJEDM_01071 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MMAEJEDM_01072 1.8e-202 oppA E ABC transporter, substratebinding protein
MMAEJEDM_01073 3.5e-218 yifK E Amino acid permease
MMAEJEDM_01074 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MMAEJEDM_01075 1.5e-56 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
MMAEJEDM_01076 5e-66 pgm3 G phosphoglycerate mutase
MMAEJEDM_01077 7.7e-253 ctpA 3.6.3.54 P P-type ATPase
MMAEJEDM_01078 4.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MMAEJEDM_01079 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MMAEJEDM_01080 2.1e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MMAEJEDM_01081 1.2e-21 K transcriptional regulator
MMAEJEDM_01082 3.2e-76 hchA S intracellular protease amidase
MMAEJEDM_01083 5.1e-137 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MMAEJEDM_01084 1.1e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MMAEJEDM_01085 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MMAEJEDM_01086 4.5e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
MMAEJEDM_01087 2.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
MMAEJEDM_01088 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MMAEJEDM_01089 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MMAEJEDM_01090 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MMAEJEDM_01091 7.4e-67 M ErfK YbiS YcfS YnhG
MMAEJEDM_01092 1e-107 XK27_08845 S ABC transporter, ATP-binding protein
MMAEJEDM_01093 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MMAEJEDM_01094 1.7e-131 ABC-SBP S ABC transporter
MMAEJEDM_01095 1.1e-158 potD P ABC transporter
MMAEJEDM_01096 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
MMAEJEDM_01097 9.5e-120 potB P ABC transporter permease
MMAEJEDM_01098 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MMAEJEDM_01099 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MMAEJEDM_01100 1.6e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
MMAEJEDM_01101 1.5e-235 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MMAEJEDM_01102 3.9e-13 S Enterocin A Immunity
MMAEJEDM_01103 2.2e-16 pspC KT PspC domain
MMAEJEDM_01104 2.4e-16 S Putative adhesin
MMAEJEDM_01105 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
MMAEJEDM_01106 8.1e-38 K transcriptional regulator PadR family
MMAEJEDM_01107 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MMAEJEDM_01108 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
MMAEJEDM_01109 6e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MMAEJEDM_01110 1.3e-118 gla U Major intrinsic protein
MMAEJEDM_01111 1.5e-45 ykuL S CBS domain
MMAEJEDM_01112 3e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MMAEJEDM_01113 2.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MMAEJEDM_01114 2.6e-86 ykuT M mechanosensitive ion channel
MMAEJEDM_01117 3e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MMAEJEDM_01118 2e-21 yheA S Belongs to the UPF0342 family
MMAEJEDM_01119 1.5e-127 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
MMAEJEDM_01120 7.8e-74 L PFAM transposase IS200-family protein
MMAEJEDM_01121 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MMAEJEDM_01123 5.4e-53 hit FG histidine triad
MMAEJEDM_01124 9.8e-95 ecsA V ABC transporter, ATP-binding protein
MMAEJEDM_01125 3.2e-71 ecsB U ABC transporter
MMAEJEDM_01126 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
MMAEJEDM_01127 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MMAEJEDM_01128 6.8e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MMAEJEDM_01129 3.1e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MMAEJEDM_01130 6.4e-187 ytgP S Polysaccharide biosynthesis protein
MMAEJEDM_01131 2.5e-63 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MMAEJEDM_01132 4.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MMAEJEDM_01133 6.6e-193 pepV 3.5.1.18 E dipeptidase PepV
MMAEJEDM_01134 7.4e-182 S Protein of unknown function DUF262
MMAEJEDM_01136 3e-36
MMAEJEDM_01137 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MMAEJEDM_01138 4.2e-61 marR K Transcriptional regulator, MarR family
MMAEJEDM_01139 1.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MMAEJEDM_01140 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MMAEJEDM_01141 5.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MMAEJEDM_01142 1.1e-98 IQ reductase
MMAEJEDM_01143 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MMAEJEDM_01144 2.3e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MMAEJEDM_01145 1e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MMAEJEDM_01146 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MMAEJEDM_01147 2.1e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MMAEJEDM_01148 5.1e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MMAEJEDM_01149 7.1e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MMAEJEDM_01150 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MMAEJEDM_01151 6.5e-55 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MMAEJEDM_01152 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MMAEJEDM_01153 5.3e-68 ybbR S YbbR-like protein
MMAEJEDM_01154 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MMAEJEDM_01155 2.4e-71 S Protein of unknown function (DUF1361)
MMAEJEDM_01156 1.2e-115 murB 1.3.1.98 M Cell wall formation
MMAEJEDM_01157 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
MMAEJEDM_01158 2.5e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MMAEJEDM_01159 1.3e-142 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MMAEJEDM_01160 6.8e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MMAEJEDM_01161 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
MMAEJEDM_01162 3.1e-42 yxjI
MMAEJEDM_01163 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MMAEJEDM_01164 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MMAEJEDM_01165 2.8e-19 secG U Preprotein translocase
MMAEJEDM_01166 9.2e-180 clcA P chloride
MMAEJEDM_01167 6.7e-146 lmrP E Major Facilitator Superfamily
MMAEJEDM_01168 1.6e-168 T PhoQ Sensor
MMAEJEDM_01169 5e-104 K response regulator
MMAEJEDM_01170 5e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MMAEJEDM_01171 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MMAEJEDM_01172 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MMAEJEDM_01173 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MMAEJEDM_01174 1.6e-55 ctsR K Belongs to the CtsR family
MMAEJEDM_01176 4.3e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MMAEJEDM_01177 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MMAEJEDM_01178 4.1e-158 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MMAEJEDM_01179 2.7e-185 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MMAEJEDM_01180 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MMAEJEDM_01188 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MMAEJEDM_01189 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MMAEJEDM_01190 1.8e-56 yqeY S YqeY-like protein
MMAEJEDM_01192 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
MMAEJEDM_01193 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMAEJEDM_01194 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MMAEJEDM_01195 1.1e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MMAEJEDM_01196 2.2e-276 yfmR S ABC transporter, ATP-binding protein
MMAEJEDM_01197 5.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MMAEJEDM_01198 4.7e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MMAEJEDM_01199 1.6e-133 yvgN C Aldo keto reductase
MMAEJEDM_01200 4.2e-35 K helix_turn_helix, mercury resistance
MMAEJEDM_01201 3.5e-113 S Aldo keto reductase
MMAEJEDM_01203 6.5e-80 ypmR E GDSL-like Lipase/Acylhydrolase
MMAEJEDM_01204 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MMAEJEDM_01205 3.6e-24 yozE S Belongs to the UPF0346 family
MMAEJEDM_01206 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MMAEJEDM_01207 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MMAEJEDM_01208 2e-32 dprA LU DNA protecting protein DprA
MMAEJEDM_01209 1.8e-82 L Transposase, IS116 IS110 IS902 family
MMAEJEDM_01210 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MMAEJEDM_01211 1e-27 ysxB J Cysteine protease Prp
MMAEJEDM_01212 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
MMAEJEDM_01215 1.2e-65 S RRXRR protein
MMAEJEDM_01220 3.7e-16 K DNA-templated transcription, initiation
MMAEJEDM_01222 1.5e-66 H Methyltransferase domain
MMAEJEDM_01223 1.4e-77 cps2D 5.1.3.2 M RmlD substrate binding domain
MMAEJEDM_01224 3.3e-41 wecD M Acetyltransferase (GNAT) family
MMAEJEDM_01226 1.8e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
MMAEJEDM_01227 3.4e-41 S Protein of unknown function (DUF1211)
MMAEJEDM_01229 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
MMAEJEDM_01230 1.2e-83 L Restriction endonuclease
MMAEJEDM_01231 3.2e-70 1.1.1.1 C Zinc-binding dehydrogenase
MMAEJEDM_01232 2.4e-31 S CHY zinc finger
MMAEJEDM_01233 1.4e-38 K Transcriptional regulator
MMAEJEDM_01234 5.2e-84 qorB 1.6.5.2 GM NmrA-like family
MMAEJEDM_01236 1.7e-16
MMAEJEDM_01237 6.7e-45 S magnesium ion binding
MMAEJEDM_01238 0.0 L Primase C terminal 2 (PriCT-2)
MMAEJEDM_01239 3.4e-262 L Helicase C-terminal domain protein
MMAEJEDM_01240 2.8e-81
MMAEJEDM_01241 3.9e-40
MMAEJEDM_01242 2.3e-50
MMAEJEDM_01243 2e-104 S AAA domain
MMAEJEDM_01244 1.1e-162 D AAA domain
MMAEJEDM_01250 1.1e-18
MMAEJEDM_01251 7.5e-13 K Cro/C1-type HTH DNA-binding domain
MMAEJEDM_01252 1.3e-43 K addiction module antidote protein HigA
MMAEJEDM_01253 3.6e-37 E IrrE N-terminal-like domain
MMAEJEDM_01254 2.6e-27 S Domain of unknown function (DUF4352)
MMAEJEDM_01255 5.3e-30
MMAEJEDM_01256 8.2e-80 sip L Belongs to the 'phage' integrase family
MMAEJEDM_01257 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MMAEJEDM_01258 7.2e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
MMAEJEDM_01259 1.5e-27 yazA L GIY-YIG catalytic domain protein
MMAEJEDM_01260 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
MMAEJEDM_01261 4e-89 plsC 2.3.1.51 I Acyltransferase
MMAEJEDM_01262 1.6e-197 dtpT U amino acid peptide transporter
MMAEJEDM_01263 1.1e-07
MMAEJEDM_01265 4.6e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MMAEJEDM_01266 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
MMAEJEDM_01267 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MMAEJEDM_01268 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MMAEJEDM_01269 1.4e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MMAEJEDM_01270 2.8e-251 yhgF K Tex-like protein N-terminal domain protein
MMAEJEDM_01271 3.6e-44 ydcK S Belongs to the SprT family
MMAEJEDM_01273 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MMAEJEDM_01274 4.5e-129 mleP2 S Sodium Bile acid symporter family
MMAEJEDM_01275 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MMAEJEDM_01276 1e-33 S Enterocin A Immunity
MMAEJEDM_01277 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
MMAEJEDM_01278 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
MMAEJEDM_01279 6.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MMAEJEDM_01280 1.6e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MMAEJEDM_01281 8.2e-154 yacL S domain protein
MMAEJEDM_01282 4.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MMAEJEDM_01283 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MMAEJEDM_01284 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MMAEJEDM_01285 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MMAEJEDM_01286 7e-71 yacP S YacP-like NYN domain
MMAEJEDM_01287 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MMAEJEDM_01288 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MMAEJEDM_01289 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
MMAEJEDM_01290 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MMAEJEDM_01291 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MMAEJEDM_01292 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MMAEJEDM_01293 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MMAEJEDM_01294 1.4e-54
MMAEJEDM_01295 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MMAEJEDM_01296 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MMAEJEDM_01297 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MMAEJEDM_01298 6.3e-45 nrdI F NrdI Flavodoxin like
MMAEJEDM_01299 2.7e-27 nrdH O Glutaredoxin
MMAEJEDM_01300 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
MMAEJEDM_01301 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MMAEJEDM_01302 8.7e-211 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MMAEJEDM_01303 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MMAEJEDM_01304 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MMAEJEDM_01305 9.2e-29 yaaL S Protein of unknown function (DUF2508)
MMAEJEDM_01306 4.7e-66 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MMAEJEDM_01307 1e-83 holB 2.7.7.7 L DNA polymerase III
MMAEJEDM_01308 1.4e-40 yabA L Involved in initiation control of chromosome replication
MMAEJEDM_01309 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MMAEJEDM_01310 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
MMAEJEDM_01311 2.3e-139 ansA 3.5.1.1 EJ Asparaginase
MMAEJEDM_01312 4.1e-69 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MMAEJEDM_01313 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MMAEJEDM_01314 1.4e-160 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MMAEJEDM_01315 3.5e-253 uup S ABC transporter, ATP-binding protein
MMAEJEDM_01316 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MMAEJEDM_01317 2.4e-33 S CAAX protease self-immunity
MMAEJEDM_01318 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MMAEJEDM_01319 5.3e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MMAEJEDM_01320 2.5e-269 aha1 P COG COG0474 Cation transport ATPase
MMAEJEDM_01321 4.1e-296 ydaO E amino acid
MMAEJEDM_01322 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
MMAEJEDM_01323 5.4e-128 comFA L Helicase C-terminal domain protein
MMAEJEDM_01324 1.2e-46 comFC S Competence protein
MMAEJEDM_01326 4.1e-11
MMAEJEDM_01328 8.5e-133 S D5 N terminal like
MMAEJEDM_01329 5.1e-46 L Bifunctional DNA primase/polymerase, N-terminal
MMAEJEDM_01338 2e-38 K COG3617 Prophage antirepressor
MMAEJEDM_01339 7.3e-21 K Transcriptional regulator
MMAEJEDM_01340 1.4e-08 K Helix-turn-helix XRE-family like proteins
MMAEJEDM_01341 2.7e-14 K Transcriptional regulator, Cro CI family
MMAEJEDM_01342 2.1e-120 sip L Belongs to the 'phage' integrase family
MMAEJEDM_01343 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MMAEJEDM_01344 9.1e-95 yeaN P Major Facilitator Superfamily
MMAEJEDM_01345 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MMAEJEDM_01346 1.1e-163 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MMAEJEDM_01347 4.5e-67 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
MMAEJEDM_01348 3.5e-86 K response regulator
MMAEJEDM_01349 1e-84 phoR 2.7.13.3 T Histidine kinase
MMAEJEDM_01350 4.1e-08 KT PspC domain protein
MMAEJEDM_01351 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MMAEJEDM_01352 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MMAEJEDM_01353 7.4e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MMAEJEDM_01354 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MMAEJEDM_01355 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MMAEJEDM_01356 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MMAEJEDM_01357 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MMAEJEDM_01358 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
MMAEJEDM_01359 1.4e-08
MMAEJEDM_01360 7.9e-43 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MMAEJEDM_01361 6.5e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MMAEJEDM_01362 3.6e-81
MMAEJEDM_01363 4.4e-82 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MMAEJEDM_01364 1.8e-113 yitU 3.1.3.104 S hydrolase
MMAEJEDM_01365 1.9e-60 speG J Acetyltransferase (GNAT) domain
MMAEJEDM_01366 7e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MMAEJEDM_01367 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MMAEJEDM_01368 1.2e-205 pipD E Dipeptidase
MMAEJEDM_01369 2.3e-45
MMAEJEDM_01370 1.2e-64 K helix_turn_helix, arabinose operon control protein
MMAEJEDM_01371 2.7e-44 S Membrane
MMAEJEDM_01372 0.0 rafA 3.2.1.22 G alpha-galactosidase
MMAEJEDM_01373 1.9e-93 L Helicase C-terminal domain protein
MMAEJEDM_01374 6.2e-42 L Helicase C-terminal domain protein
MMAEJEDM_01376 3.6e-145 pbuO_1 S Permease family
MMAEJEDM_01377 3.8e-16
MMAEJEDM_01379 1.7e-22 L HNH nucleases
MMAEJEDM_01380 2.9e-33 L Phage terminase, small subunit
MMAEJEDM_01381 1.1e-216 S Terminase
MMAEJEDM_01382 4.7e-102 S Phage portal protein, HK97 family
MMAEJEDM_01383 4.7e-73 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MMAEJEDM_01384 1.1e-94 S Phage capsid family
MMAEJEDM_01385 1.8e-13 L Phage gp6-like head-tail connector protein
MMAEJEDM_01387 2.7e-12 S Bacteriophage HK97-gp10, putative tail-component
MMAEJEDM_01389 2.1e-24 S Phage tail tube protein
MMAEJEDM_01391 1.3e-106 M Phage tail tape measure protein TP901
MMAEJEDM_01392 2.3e-81 S Phage tail protein
MMAEJEDM_01393 5.4e-275 rny D peptidase
MMAEJEDM_01394 3e-99 M Prophage endopeptidase tail
MMAEJEDM_01395 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MMAEJEDM_01396 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MMAEJEDM_01397 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MMAEJEDM_01398 7.3e-105
MMAEJEDM_01399 3.2e-117
MMAEJEDM_01400 1.3e-41 dut S dUTPase
MMAEJEDM_01401 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MMAEJEDM_01402 3.7e-46 yqhY S Asp23 family, cell envelope-related function
MMAEJEDM_01403 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MMAEJEDM_01404 1e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MMAEJEDM_01405 8.9e-147 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MMAEJEDM_01406 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MMAEJEDM_01407 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MMAEJEDM_01408 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MMAEJEDM_01409 6.6e-49 argR K Regulates arginine biosynthesis genes
MMAEJEDM_01410 7.1e-178 recN L May be involved in recombinational repair of damaged DNA
MMAEJEDM_01411 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MMAEJEDM_01412 2.2e-30 ynzC S UPF0291 protein
MMAEJEDM_01413 2.9e-26 yneF S UPF0154 protein
MMAEJEDM_01414 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
MMAEJEDM_01415 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MMAEJEDM_01416 3.1e-76 yciQ P membrane protein (DUF2207)
MMAEJEDM_01417 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MMAEJEDM_01418 4.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MMAEJEDM_01419 1.2e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MMAEJEDM_01420 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MMAEJEDM_01421 5.5e-80 dnaB L replication initiation and membrane attachment
MMAEJEDM_01422 1.6e-107 dnaI L Primosomal protein DnaI
MMAEJEDM_01423 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MMAEJEDM_01424 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MMAEJEDM_01425 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MMAEJEDM_01426 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MMAEJEDM_01427 1.9e-71 yqeG S HAD phosphatase, family IIIA
MMAEJEDM_01428 2.7e-181 yqeH S Ribosome biogenesis GTPase YqeH
MMAEJEDM_01429 6e-30 yhbY J RNA-binding protein
MMAEJEDM_01430 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MMAEJEDM_01431 2.6e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MMAEJEDM_01432 5.1e-49 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MMAEJEDM_01433 5.5e-82 H Nodulation protein S (NodS)
MMAEJEDM_01434 1.3e-122 ylbM S Belongs to the UPF0348 family
MMAEJEDM_01435 3.5e-57 yceD S Uncharacterized ACR, COG1399
MMAEJEDM_01436 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MMAEJEDM_01437 2.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MMAEJEDM_01438 1.9e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MMAEJEDM_01439 1.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MMAEJEDM_01440 9.5e-95 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MMAEJEDM_01441 3.4e-225 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MMAEJEDM_01442 1.4e-36 ypmB S Protein conserved in bacteria
MMAEJEDM_01443 5.3e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MMAEJEDM_01444 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MMAEJEDM_01445 5.1e-56 dnaD L DnaD domain protein
MMAEJEDM_01446 1.5e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MMAEJEDM_01447 2.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MMAEJEDM_01448 1.3e-125 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMAEJEDM_01449 6.2e-92 M transferase activity, transferring glycosyl groups
MMAEJEDM_01450 7e-83 M Glycosyltransferase sugar-binding region containing DXD motif
MMAEJEDM_01451 5.8e-100 epsJ1 M Glycosyltransferase like family 2
MMAEJEDM_01454 7.1e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MMAEJEDM_01455 4.1e-15 ywzB S Protein of unknown function (DUF1146)
MMAEJEDM_01456 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MMAEJEDM_01457 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MMAEJEDM_01458 5.1e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MMAEJEDM_01459 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MMAEJEDM_01460 4.1e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MMAEJEDM_01461 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MMAEJEDM_01462 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MMAEJEDM_01463 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
MMAEJEDM_01464 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MMAEJEDM_01465 1.3e-134 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MMAEJEDM_01466 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MMAEJEDM_01467 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MMAEJEDM_01468 6.8e-86 tdk 2.7.1.21 F thymidine kinase
MMAEJEDM_01469 1e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MMAEJEDM_01470 3.5e-110 cobQ S glutamine amidotransferase
MMAEJEDM_01471 9.4e-202 FbpA K Fibronectin-binding protein
MMAEJEDM_01472 3.1e-40 K Transcriptional regulator
MMAEJEDM_01473 3.5e-117 K Primase C terminal 1 (PriCT-1)
MMAEJEDM_01475 2.1e-12 S Thioredoxin
MMAEJEDM_01477 7.5e-07 L Integrase core domain
MMAEJEDM_01478 4.2e-40
MMAEJEDM_01490 2.6e-16 S RelB antitoxin
MMAEJEDM_01491 4.6e-37
MMAEJEDM_01492 1.1e-13
MMAEJEDM_01493 1.2e-09
MMAEJEDM_01496 1.4e-178 pre D Plasmid recombination enzyme
MMAEJEDM_01497 4.3e-237 tetL EGP Major Facilitator Superfamily
MMAEJEDM_01498 0.0 tetP J elongation factor G
MMAEJEDM_01499 3.7e-265 D Domain of unknown function DUF87
MMAEJEDM_01500 1e-63 S Bacterial protein of unknown function (DUF961)
MMAEJEDM_01501 2.3e-53 S Bacterial protein of unknown function (DUF961)
MMAEJEDM_01502 4e-48 L Resolvase, N terminal domain
MMAEJEDM_01505 5.3e-18
MMAEJEDM_01506 8.8e-53 L Protein involved in initiation of plasmid replication
MMAEJEDM_01510 3e-89 S Acyltransferase family
MMAEJEDM_01511 6e-161 purD 6.3.4.13 F Belongs to the GARS family
MMAEJEDM_01512 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MMAEJEDM_01513 1.2e-74 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MMAEJEDM_01514 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MMAEJEDM_01515 5.5e-227 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MMAEJEDM_01516 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MMAEJEDM_01517 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MMAEJEDM_01518 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MMAEJEDM_01519 2.9e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MMAEJEDM_01520 8.2e-07 fhaB M Rib/alpha-like repeat
MMAEJEDM_01521 4.7e-31 3.2.1.18 GH33 M Rib/alpha-like repeat
MMAEJEDM_01522 3.9e-95 3.2.1.18 GH33 M Rib/alpha-like repeat
MMAEJEDM_01523 1.9e-95 ypuA S Protein of unknown function (DUF1002)
MMAEJEDM_01524 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
MMAEJEDM_01525 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MMAEJEDM_01526 9.3e-37 yncA 2.3.1.79 S Maltose acetyltransferase
MMAEJEDM_01527 1.5e-205 yflS P Sodium:sulfate symporter transmembrane region
MMAEJEDM_01528 6.1e-199 frdC 1.3.5.4 C FAD binding domain
MMAEJEDM_01529 1.1e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MMAEJEDM_01530 5.7e-14 ybaN S Protein of unknown function (DUF454)
MMAEJEDM_01531 3.1e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MMAEJEDM_01539 5.6e-22 S by MetaGeneAnnotator
MMAEJEDM_01540 2.2e-07 M PFAM Cna B domain protein
MMAEJEDM_01541 8.1e-27 3.4.22.70 M Sortase family
MMAEJEDM_01542 2.1e-89 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
MMAEJEDM_01543 1.4e-44 3.4.22.70 M Sortase family
MMAEJEDM_01546 6.8e-25 L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MMAEJEDM_01547 2e-57 S AAA domain, putative AbiEii toxin, Type IV TA system
MMAEJEDM_01548 5.6e-13 S RloB-like protein
MMAEJEDM_01549 3.3e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MMAEJEDM_01561 1.9e-21 ssb L Single-stranded DNA-binding protein
MMAEJEDM_01562 1.5e-86 endA F DNA RNA non-specific endonuclease
MMAEJEDM_01563 2.4e-131 NU StbA protein
MMAEJEDM_01565 6.6e-08 S Uncharacterized protein pXO2-11
MMAEJEDM_01566 4.3e-40
MMAEJEDM_01567 4.4e-196 trsE S COG0433 Predicted ATPase
MMAEJEDM_01568 5.1e-28 trsE S COG0433 Predicted ATPase
MMAEJEDM_01570 2.6e-60 M Peptidase family M23
MMAEJEDM_01573 1.2e-117 S Uncharacterised protein family (UPF0236)
MMAEJEDM_01574 1.8e-116 degV S EDD domain protein, DegV family
MMAEJEDM_01575 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
MMAEJEDM_01576 1e-30 6.3.3.2 I Protein conserved in bacteria
MMAEJEDM_01577 1.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MMAEJEDM_01578 5.9e-80 yjjH S Calcineurin-like phosphoesterase
MMAEJEDM_01579 1.8e-95 EG EamA-like transporter family
MMAEJEDM_01580 2.5e-84 natB CP ABC-type Na efflux pump, permease component
MMAEJEDM_01581 6.2e-112 natA S Domain of unknown function (DUF4162)
MMAEJEDM_01582 6.2e-23 K Acetyltransferase (GNAT) domain
MMAEJEDM_01584 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MMAEJEDM_01585 7.7e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MMAEJEDM_01586 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
MMAEJEDM_01587 5.3e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
MMAEJEDM_01588 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MMAEJEDM_01589 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MMAEJEDM_01590 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
MMAEJEDM_01591 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MMAEJEDM_01592 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
MMAEJEDM_01593 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
MMAEJEDM_01594 4.6e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MMAEJEDM_01595 2.8e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MMAEJEDM_01596 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MMAEJEDM_01597 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
MMAEJEDM_01598 6.8e-84 lytH 3.5.1.28 M Ami_3
MMAEJEDM_01599 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MMAEJEDM_01600 7.7e-12 M Lysin motif
MMAEJEDM_01601 1.9e-126 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MMAEJEDM_01602 1.3e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
MMAEJEDM_01603 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
MMAEJEDM_01604 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MMAEJEDM_01605 1.2e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MMAEJEDM_01606 9.6e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MMAEJEDM_01607 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MMAEJEDM_01608 7.6e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
MMAEJEDM_01609 9.7e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MMAEJEDM_01610 7.9e-91 L PFAM Integrase catalytic region
MMAEJEDM_01611 2.6e-30 L Helix-turn-helix domain
MMAEJEDM_01613 4.1e-68 sip L Belongs to the 'phage' integrase family
MMAEJEDM_01614 3e-14 S Acyltransferase family
MMAEJEDM_01615 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MMAEJEDM_01616 2.3e-122 K LysR substrate binding domain
MMAEJEDM_01618 2.2e-20
MMAEJEDM_01619 4e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MMAEJEDM_01620 3.4e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
MMAEJEDM_01621 3.1e-50 comEA L Competence protein ComEA
MMAEJEDM_01622 2e-69 comEB 3.5.4.12 F ComE operon protein 2
MMAEJEDM_01623 2.7e-156 comEC S Competence protein ComEC
MMAEJEDM_01624 8.4e-105 holA 2.7.7.7 L DNA polymerase III delta subunit
MMAEJEDM_01625 6.6e-232 L Transposase
MMAEJEDM_01626 9.4e-94 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
MMAEJEDM_01627 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MMAEJEDM_01628 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MMAEJEDM_01629 4.2e-21 cutC P Participates in the control of copper homeostasis
MMAEJEDM_01630 8.1e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MMAEJEDM_01631 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MMAEJEDM_01632 2.1e-98 rrmA 2.1.1.187 H Methyltransferase
MMAEJEDM_01633 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MMAEJEDM_01634 1e-283 ftsK D Belongs to the FtsK SpoIIIE SftA family
MMAEJEDM_01635 1.6e-108 ymfF S Peptidase M16 inactive domain protein
MMAEJEDM_01636 2.4e-149 ymfH S Peptidase M16
MMAEJEDM_01637 2.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
MMAEJEDM_01638 2.9e-64 ymfM S Helix-turn-helix domain
MMAEJEDM_01639 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MMAEJEDM_01640 7.8e-49 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
MMAEJEDM_01641 3.5e-22 S Cytochrome B5
MMAEJEDM_01642 4e-19 sigH K DNA-templated transcription, initiation
MMAEJEDM_01643 3.4e-69 recX 2.4.1.337 GT4 S Regulatory protein RecX
MMAEJEDM_01644 6.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MMAEJEDM_01645 2.6e-97 ygaC J Belongs to the UPF0374 family
MMAEJEDM_01646 2.4e-92 yueF S AI-2E family transporter
MMAEJEDM_01647 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MMAEJEDM_01648 1.8e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MMAEJEDM_01649 4e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MMAEJEDM_01650 0.0 lacL 3.2.1.23 G -beta-galactosidase
MMAEJEDM_01653 6.3e-09
MMAEJEDM_01654 2.8e-16 L DnaD domain protein
MMAEJEDM_01661 1.3e-47 S Phage regulatory protein Rha (Phage_pRha)
MMAEJEDM_01663 6.4e-16 S sequence-specific DNA binding
MMAEJEDM_01664 2.5e-121 sip L Belongs to the 'phage' integrase family
MMAEJEDM_01665 1.2e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
MMAEJEDM_01666 2.2e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MMAEJEDM_01667 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
MMAEJEDM_01668 3.9e-69 ybhL S Belongs to the BI1 family
MMAEJEDM_01669 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MMAEJEDM_01670 1.3e-73 draG O ADP-ribosylglycohydrolase
MMAEJEDM_01672 9.8e-185 L Probable transposase
MMAEJEDM_01673 1.2e-21 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
MMAEJEDM_01674 1.2e-78 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
MMAEJEDM_01675 0.0 S Bacterial membrane protein YfhO
MMAEJEDM_01676 5.1e-53 gtcA S Teichoic acid glycosylation protein
MMAEJEDM_01677 5.1e-54 fld C Flavodoxin
MMAEJEDM_01678 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
MMAEJEDM_01679 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MMAEJEDM_01680 4.7e-12 mltD CBM50 M Lysin motif
MMAEJEDM_01681 3.8e-93 yihY S Belongs to the UPF0761 family
MMAEJEDM_01683 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MMAEJEDM_01684 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
MMAEJEDM_01685 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MMAEJEDM_01686 2.1e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MMAEJEDM_01687 5.6e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MMAEJEDM_01688 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MMAEJEDM_01689 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MMAEJEDM_01690 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MMAEJEDM_01691 1.8e-12 yajC U Preprotein translocase
MMAEJEDM_01692 1.7e-100 M Prophage endopeptidase tail
MMAEJEDM_01693 1.7e-60 S Phage tail protein
MMAEJEDM_01694 1.2e-104 M Phage tail tape measure protein TP901
MMAEJEDM_01695 6.3e-39 S Bacteriophage Gp15 protein
MMAEJEDM_01697 7.5e-38 N domain, Protein
MMAEJEDM_01698 7.6e-17 S Minor capsid protein from bacteriophage
MMAEJEDM_01699 1e-15 S Minor capsid protein
MMAEJEDM_01700 2.6e-29 S Minor capsid protein
MMAEJEDM_01701 4.4e-14
MMAEJEDM_01702 2.5e-97 S T=7 icosahedral viral capsid
MMAEJEDM_01703 3.5e-15 S Phage minor structural protein GP20
MMAEJEDM_01704 5.8e-112 dkg S reductase
MMAEJEDM_01705 1.3e-24
MMAEJEDM_01706 9.3e-62 L Resolvase, N-terminal domain
MMAEJEDM_01707 1.4e-99 L Probable transposase
MMAEJEDM_01708 6.2e-174 arsB 1.20.4.1 P Sodium Bile acid symporter family
MMAEJEDM_01709 8.5e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MMAEJEDM_01710 3.1e-36
MMAEJEDM_01711 0.0 pepN 3.4.11.2 E aminopeptidase
MMAEJEDM_01712 3.2e-35
MMAEJEDM_01714 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
MMAEJEDM_01715 6.6e-63 licT K transcriptional antiterminator
MMAEJEDM_01716 1.4e-28 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MMAEJEDM_01717 8.9e-289 lacS G Transporter
MMAEJEDM_01718 5.9e-111 galR K Transcriptional regulator
MMAEJEDM_01719 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MMAEJEDM_01720 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MMAEJEDM_01721 5.9e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MMAEJEDM_01722 3e-311 rafA 3.2.1.22 G alpha-galactosidase
MMAEJEDM_01723 1.1e-104 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
MMAEJEDM_01724 2.1e-21 XK27_09445 S Domain of unknown function (DUF1827)
MMAEJEDM_01726 1.8e-19 D nuclear chromosome segregation
MMAEJEDM_01727 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MMAEJEDM_01728 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MMAEJEDM_01729 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
MMAEJEDM_01730 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
MMAEJEDM_01731 4.7e-158 glk 2.7.1.2 G Glucokinase
MMAEJEDM_01732 1.4e-45 yqhL P Rhodanese-like protein
MMAEJEDM_01733 2.8e-16 WQ51_02665 S Protein of unknown function (DUF3042)
MMAEJEDM_01734 5.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MMAEJEDM_01735 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
MMAEJEDM_01736 1.3e-45 glnR K Transcriptional regulator
MMAEJEDM_01737 2e-247 glnA 6.3.1.2 E glutamine synthetase
MMAEJEDM_01738 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MMAEJEDM_01739 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MMAEJEDM_01740 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MMAEJEDM_01741 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MMAEJEDM_01742 2.9e-137 cggR K Putative sugar-binding domain
MMAEJEDM_01744 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MMAEJEDM_01745 1.8e-149 whiA K May be required for sporulation
MMAEJEDM_01746 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MMAEJEDM_01747 7.5e-126 rapZ S Displays ATPase and GTPase activities
MMAEJEDM_01748 1.8e-131 ylbL T Belongs to the peptidase S16 family
MMAEJEDM_01749 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MMAEJEDM_01750 1e-72 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MMAEJEDM_01751 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MMAEJEDM_01752 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MMAEJEDM_01753 3e-101 ftsW D Belongs to the SEDS family
MMAEJEDM_01754 3.3e-148 manN G system, mannose fructose sorbose family IID component
MMAEJEDM_01755 7e-115 manY G PTS system
MMAEJEDM_01756 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MMAEJEDM_01757 0.0 typA T GTP-binding protein TypA
MMAEJEDM_01758 6.3e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MMAEJEDM_01759 1.2e-24 yktA S Belongs to the UPF0223 family
MMAEJEDM_01760 2.6e-30 1.1.1.27 C L-malate dehydrogenase activity
MMAEJEDM_01761 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MMAEJEDM_01762 9.5e-25
MMAEJEDM_01763 5e-23 ykzG S Belongs to the UPF0356 family
MMAEJEDM_01764 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MMAEJEDM_01765 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MMAEJEDM_01766 7.8e-198 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MMAEJEDM_01767 7.8e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MMAEJEDM_01768 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MMAEJEDM_01769 6.1e-19 S Tetratricopeptide repeat
MMAEJEDM_01770 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MMAEJEDM_01771 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MMAEJEDM_01772 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MMAEJEDM_01773 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
MMAEJEDM_01774 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MMAEJEDM_01775 8.2e-199 yfnA E amino acid
MMAEJEDM_01776 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
MMAEJEDM_01777 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MMAEJEDM_01778 1.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MMAEJEDM_01779 3.8e-27 ylqC S Belongs to the UPF0109 family
MMAEJEDM_01780 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MMAEJEDM_01781 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MMAEJEDM_01782 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MMAEJEDM_01783 7.2e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MMAEJEDM_01784 1.3e-208 smc D Required for chromosome condensation and partitioning
MMAEJEDM_01785 4.3e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MMAEJEDM_01786 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MMAEJEDM_01787 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MMAEJEDM_01788 4e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MMAEJEDM_01789 1.3e-238 yloV S DAK2 domain fusion protein YloV
MMAEJEDM_01790 4.5e-53 asp S Asp23 family, cell envelope-related function
MMAEJEDM_01791 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MMAEJEDM_01792 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
MMAEJEDM_01793 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MMAEJEDM_01794 7.5e-191 KLT serine threonine protein kinase
MMAEJEDM_01795 3.3e-90 stp 3.1.3.16 T phosphatase
MMAEJEDM_01796 1.3e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MMAEJEDM_01797 1.3e-139 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MMAEJEDM_01798 4.6e-287 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MMAEJEDM_01799 2.2e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MMAEJEDM_01800 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MMAEJEDM_01801 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MMAEJEDM_01802 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
MMAEJEDM_01803 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
MMAEJEDM_01804 6.1e-187 rodA D Belongs to the SEDS family
MMAEJEDM_01805 1.3e-13 S Protein of unknown function (DUF2969)
MMAEJEDM_01806 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MMAEJEDM_01807 3.4e-167 mbl D Cell shape determining protein MreB Mrl
MMAEJEDM_01808 3.5e-34 S N-acetylmuramoyl-L-alanine amidase activity
MMAEJEDM_01809 3.8e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MMAEJEDM_01810 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
MMAEJEDM_01811 1.8e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MMAEJEDM_01812 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MMAEJEDM_01813 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MMAEJEDM_01814 6.9e-43 yodB K Transcriptional regulator, HxlR family
MMAEJEDM_01815 8e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MMAEJEDM_01816 3.8e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MMAEJEDM_01820 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
MMAEJEDM_01821 3.3e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MMAEJEDM_01822 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MMAEJEDM_01823 3.6e-220 cydD CO ABC transporter transmembrane region
MMAEJEDM_01824 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MMAEJEDM_01825 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MMAEJEDM_01826 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
MMAEJEDM_01827 2.3e-208 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MMAEJEDM_01828 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MMAEJEDM_01831 2.9e-147 V Pfam:Methyltransf_26
MMAEJEDM_01832 1.1e-181 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MMAEJEDM_01833 1.3e-167 arlS 2.7.13.3 T Histidine kinase
MMAEJEDM_01834 3.1e-111 K response regulator
MMAEJEDM_01836 1.7e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MMAEJEDM_01837 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MMAEJEDM_01838 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MMAEJEDM_01839 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MMAEJEDM_01840 5.8e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MMAEJEDM_01841 6.9e-37
MMAEJEDM_01842 1.6e-55 S N-acetylmuramoyl-L-alanine amidase activity
MMAEJEDM_01849 5.8e-79 copY K Penicillinase repressor
MMAEJEDM_01850 0.0 3.6.3.4 P haloacid dehalogenase-like hydrolase
MMAEJEDM_01851 2.4e-40 S membrane protein (DUF2078)
MMAEJEDM_01852 4.8e-16 3.2.1.23 S Domain of unknown function DUF302
MMAEJEDM_01853 1.5e-33 3.2.1.23 S Domain of unknown function DUF302
MMAEJEDM_01854 3.2e-181 pbuG S permease
MMAEJEDM_01855 6.4e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
MMAEJEDM_01856 9e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MMAEJEDM_01857 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MMAEJEDM_01858 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MMAEJEDM_01859 1.5e-144 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MMAEJEDM_01860 5.4e-13
MMAEJEDM_01861 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
MMAEJEDM_01862 1.2e-44 L snf2 family
MMAEJEDM_01864 1.4e-18
MMAEJEDM_01865 2e-25 L VRR_NUC
MMAEJEDM_01866 9.5e-127 L AAA domain
MMAEJEDM_01867 1.9e-35 S Protein of unknown function (DUF669)
MMAEJEDM_01868 1.9e-178 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
MMAEJEDM_01869 1.2e-157 S Phage plasmid primase, P4 family
MMAEJEDM_01871 3.1e-50 S VRR_NUC
MMAEJEDM_01872 7.9e-230 S Virulence-associated protein E
MMAEJEDM_01873 9.5e-141 S Bifunctional DNA primase/polymerase, N-terminal
MMAEJEDM_01874 8.1e-85
MMAEJEDM_01875 1.6e-116 L AAA domain
MMAEJEDM_01876 2.6e-242 res L Helicase C-terminal domain protein
MMAEJEDM_01877 4.1e-78 S Siphovirus Gp157
MMAEJEDM_01884 2.3e-94 S Phage minor capsid protein 2
MMAEJEDM_01885 2.1e-144 S Phage portal protein, SPP1 Gp6-like
MMAEJEDM_01886 4.9e-166 S Pfam:Terminase_3C
MMAEJEDM_01887 2.2e-23
MMAEJEDM_01889 1e-11 arpU S Phage transcriptional regulator, ArpU family
MMAEJEDM_01894 6.8e-73 gshR 1.8.1.7 C Glutathione reductase
MMAEJEDM_01895 4.9e-179 proV E ABC transporter, ATP-binding protein
MMAEJEDM_01896 5.3e-263 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MMAEJEDM_01899 3.8e-182 steT E amino acid
MMAEJEDM_01900 5.8e-22 K Acetyltransferase (GNAT) domain
MMAEJEDM_01901 8e-145 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MMAEJEDM_01902 1.3e-33 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MMAEJEDM_01903 6e-74 K rpiR family
MMAEJEDM_01904 3.6e-166 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MMAEJEDM_01905 3.7e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
MMAEJEDM_01906 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MMAEJEDM_01907 1e-100 rplD J Forms part of the polypeptide exit tunnel
MMAEJEDM_01908 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MMAEJEDM_01909 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MMAEJEDM_01910 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MMAEJEDM_01911 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MMAEJEDM_01912 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MMAEJEDM_01913 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MMAEJEDM_01914 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
MMAEJEDM_01915 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MMAEJEDM_01916 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MMAEJEDM_01917 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MMAEJEDM_01918 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MMAEJEDM_01919 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MMAEJEDM_01920 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MMAEJEDM_01921 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MMAEJEDM_01922 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MMAEJEDM_01923 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MMAEJEDM_01924 2.1e-22 rpmD J Ribosomal protein L30
MMAEJEDM_01925 1e-67 rplO J Binds to the 23S rRNA
MMAEJEDM_01926 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MMAEJEDM_01927 3.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MMAEJEDM_01928 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MMAEJEDM_01929 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MMAEJEDM_01930 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MMAEJEDM_01931 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MMAEJEDM_01932 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MMAEJEDM_01933 4.8e-53 rplQ J Ribosomal protein L17
MMAEJEDM_01934 6.1e-101 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMAEJEDM_01935 1.5e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMAEJEDM_01936 2.2e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MMAEJEDM_01937 4.2e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MMAEJEDM_01938 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MMAEJEDM_01939 4.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
MMAEJEDM_01940 1.8e-30
MMAEJEDM_01941 2e-245 yjbQ P TrkA C-terminal domain protein
MMAEJEDM_01942 0.0 helD 3.6.4.12 L DNA helicase
MMAEJEDM_01943 4.7e-68 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MMAEJEDM_01944 2e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MMAEJEDM_01945 4.5e-101 hrtB V ABC transporter permease
MMAEJEDM_01946 3e-34 ygfC K Bacterial regulatory proteins, tetR family
MMAEJEDM_01947 8.2e-86 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MMAEJEDM_01948 1.2e-276 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MMAEJEDM_01949 5.5e-45 M LysM domain protein
MMAEJEDM_01950 1.8e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MMAEJEDM_01951 1.6e-93 sbcC L Putative exonuclease SbcCD, C subunit
MMAEJEDM_01952 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
MMAEJEDM_01953 7.2e-53 perR P Belongs to the Fur family
MMAEJEDM_01954 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MMAEJEDM_01955 8.1e-142 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MMAEJEDM_01956 1.6e-85 S (CBS) domain
MMAEJEDM_01957 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MMAEJEDM_01958 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MMAEJEDM_01959 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MMAEJEDM_01960 7.3e-140 yabM S Polysaccharide biosynthesis protein
MMAEJEDM_01961 3.6e-31 yabO J S4 domain protein
MMAEJEDM_01962 9.1e-17 divIC D Septum formation initiator
MMAEJEDM_01963 1.1e-40 yabR J RNA binding
MMAEJEDM_01964 9.5e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MMAEJEDM_01965 1.9e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MMAEJEDM_01966 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MMAEJEDM_01967 2.7e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MMAEJEDM_01968 3.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MMAEJEDM_01969 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MMAEJEDM_01970 2.4e-192 cycA E Amino acid permease
MMAEJEDM_01971 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MMAEJEDM_01972 1.6e-176 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MMAEJEDM_01982 2.1e-07
MMAEJEDM_01988 2.1e-53 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MMAEJEDM_01989 1.1e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MMAEJEDM_01990 1e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
MMAEJEDM_01991 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MMAEJEDM_01992 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
MMAEJEDM_01993 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MMAEJEDM_01994 6.4e-18 D nuclear chromosome segregation
MMAEJEDM_01996 1e-63 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
MMAEJEDM_01997 2.8e-145 2.1.1.72 V N-6 DNA Methylase
MMAEJEDM_01998 3.5e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MMAEJEDM_01999 2.4e-118 ytbE S reductase
MMAEJEDM_02000 3e-41 ytcD K HxlR-like helix-turn-helix
MMAEJEDM_02001 2.5e-101 ybbM S Uncharacterised protein family (UPF0014)
MMAEJEDM_02002 4.5e-67 ybbL S ABC transporter
MMAEJEDM_02003 6.2e-163 oxlT P Major Facilitator Superfamily
MMAEJEDM_02004 4.7e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MMAEJEDM_02005 2.4e-47 S Short repeat of unknown function (DUF308)
MMAEJEDM_02008 1e-39 ypaA S Protein of unknown function (DUF1304)
MMAEJEDM_02009 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MMAEJEDM_02010 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MMAEJEDM_02011 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MMAEJEDM_02012 5.6e-36 M Phage tail tape measure protein TP901
MMAEJEDM_02013 5.5e-131 S Phage tail protein
MMAEJEDM_02014 3.3e-285 rny D peptidase
MMAEJEDM_02017 1e-68 S Domain of unknown function (DUF2479)
MMAEJEDM_02018 6.1e-13 XK27_06935 K Transcriptional regulator C-terminal region
MMAEJEDM_02019 4.5e-151 yfeX P Peroxidase
MMAEJEDM_02020 7.8e-18 S Protein of unknown function (DUF3021)
MMAEJEDM_02021 5.3e-40 K LytTr DNA-binding domain
MMAEJEDM_02022 6.9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MMAEJEDM_02023 3.5e-207 mmuP E amino acid
MMAEJEDM_02024 9.2e-16 psiE S Phosphate-starvation-inducible E
MMAEJEDM_02025 1.5e-77 infB UW LPXTG-motif cell wall anchor domain protein
MMAEJEDM_02028 1.5e-68 2.3.1.178 J Acetyltransferase (GNAT) domain
MMAEJEDM_02029 1.6e-167 yjjP S Putative threonine/serine exporter
MMAEJEDM_02030 4.8e-109 glcU U sugar transport
MMAEJEDM_02031 5.9e-15 K regulatory protein TetR
MMAEJEDM_02032 1.3e-27 mdtG EGP Major facilitator Superfamily
MMAEJEDM_02033 3.5e-116 mdtG EGP Major facilitator Superfamily
MMAEJEDM_02034 5e-143 2.1.1.14 E methionine synthase, vitamin-B12 independent
MMAEJEDM_02035 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
MMAEJEDM_02036 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MMAEJEDM_02037 9.6e-68 metI P ABC transporter permease
MMAEJEDM_02038 8.8e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MMAEJEDM_02039 3e-84 drgA C nitroreductase
MMAEJEDM_02040 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
MMAEJEDM_02041 2.3e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
MMAEJEDM_02042 1.3e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MMAEJEDM_02043 3.3e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MMAEJEDM_02045 2.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MMAEJEDM_02046 2.4e-31 metI U ABC transporter permease
MMAEJEDM_02047 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
MMAEJEDM_02048 2.3e-34 S Protein of unknown function (DUF4256)
MMAEJEDM_02051 5.2e-177 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MMAEJEDM_02052 2.8e-166 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MMAEJEDM_02053 2.9e-179 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MMAEJEDM_02054 4e-230 lpdA 1.8.1.4 C Dehydrogenase
MMAEJEDM_02055 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
MMAEJEDM_02056 9.2e-56 S Protein of unknown function (DUF975)
MMAEJEDM_02057 1.1e-76 E GDSL-like Lipase/Acylhydrolase family
MMAEJEDM_02058 2.3e-38
MMAEJEDM_02059 4.1e-27 gcvR T Belongs to the UPF0237 family
MMAEJEDM_02060 1.1e-218 XK27_08635 S UPF0210 protein
MMAEJEDM_02061 9e-88 fruR K DeoR C terminal sensor domain
MMAEJEDM_02062 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MMAEJEDM_02063 4.8e-282 fruA 2.7.1.202 GT Phosphotransferase System
MMAEJEDM_02064 2e-49 cps3F
MMAEJEDM_02065 2.1e-83 S Membrane
MMAEJEDM_02066 1.8e-254 E Amino acid permease
MMAEJEDM_02067 2.9e-225 cadA P P-type ATPase
MMAEJEDM_02068 6.4e-114 degV S EDD domain protein, DegV family
MMAEJEDM_02069 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MMAEJEDM_02070 5.6e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
MMAEJEDM_02071 7.2e-27 ydiI Q Thioesterase superfamily
MMAEJEDM_02072 4.3e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MMAEJEDM_02073 1.3e-138 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MMAEJEDM_02074 4.7e-81 S L,D-transpeptidase catalytic domain
MMAEJEDM_02075 1.5e-165 EGP Major facilitator Superfamily
MMAEJEDM_02076 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
MMAEJEDM_02077 1.7e-225 pipD E Dipeptidase
MMAEJEDM_02078 7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MMAEJEDM_02079 2.6e-32 ywjH S Protein of unknown function (DUF1634)
MMAEJEDM_02080 1.7e-119 yxaA S membrane transporter protein
MMAEJEDM_02081 7.6e-83 lysR5 K LysR substrate binding domain
MMAEJEDM_02082 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
MMAEJEDM_02083 1.2e-13 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MMAEJEDM_02084 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MMAEJEDM_02085 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MMAEJEDM_02086 5.5e-243 lysP E amino acid
MMAEJEDM_02087 3.6e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MMAEJEDM_02088 0.0 clpE O Belongs to the ClpA ClpB family
MMAEJEDM_02089 1.5e-15
MMAEJEDM_02090 9.7e-37 ptsH G phosphocarrier protein HPR
MMAEJEDM_02091 6.9e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MMAEJEDM_02092 7.5e-69 rny D Peptidase family M23
MMAEJEDM_02094 2.3e-138 tetA EGP Major facilitator Superfamily
MMAEJEDM_02095 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
MMAEJEDM_02096 3.6e-213 yjeM E Amino Acid
MMAEJEDM_02097 6.9e-12 D Antitoxin component of a toxin-antitoxin (TA) module
MMAEJEDM_02098 1.6e-22 S PIN domain
MMAEJEDM_02102 7e-60 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
MMAEJEDM_02103 1.5e-07
MMAEJEDM_02104 1.4e-30 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
MMAEJEDM_02108 1.4e-67 spx4 1.20.4.1 P ArsC family
MMAEJEDM_02109 1.8e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MMAEJEDM_02110 2.9e-230 baeS 2.7.13.3 T Histidine kinase
MMAEJEDM_02111 5e-117 K response regulator
MMAEJEDM_02112 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
MMAEJEDM_02113 9e-102 qmcA O prohibitin homologues
MMAEJEDM_02114 5.4e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
MMAEJEDM_02115 1.1e-14 tnp L Transposase IS66 family
MMAEJEDM_02116 5.4e-85 dps P Ferritin-like domain
MMAEJEDM_02117 3e-125 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MMAEJEDM_02118 2.1e-53 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MMAEJEDM_02119 9.6e-78 glnP P ABC transporter permease
MMAEJEDM_02120 1.2e-85 gluC P ABC transporter permease
MMAEJEDM_02121 4.3e-99 glnH ET ABC transporter
MMAEJEDM_02122 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MMAEJEDM_02123 1.5e-10
MMAEJEDM_02124 9.4e-59 D NLP P60 protein
MMAEJEDM_02125 1e-77 S Phage tail protein
MMAEJEDM_02126 7.6e-79 M Prophage endopeptidase tail
MMAEJEDM_02127 9.1e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
MMAEJEDM_02128 3.1e-27 xlyB 3.5.1.28 CBM50 M LysM domain
MMAEJEDM_02129 5e-19 glpE P Rhodanese Homology Domain
MMAEJEDM_02130 4.2e-49 lytE M LysM domain protein
MMAEJEDM_02134 1.3e-15
MMAEJEDM_02137 5.6e-07 comD 2.7.13.3 T GHKL domain
MMAEJEDM_02139 9.7e-96 cadD P cadmium resistance
MMAEJEDM_02140 2e-111 ampC V Beta-lactamase
MMAEJEDM_02141 1.5e-31
MMAEJEDM_02142 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MMAEJEDM_02143 9.2e-206 glnP P ABC transporter
MMAEJEDM_02144 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MMAEJEDM_02145 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MMAEJEDM_02146 1.7e-162 iscS2 2.8.1.7 E Aminotransferase class V
MMAEJEDM_02147 7.1e-173 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MMAEJEDM_02148 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
MMAEJEDM_02149 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MMAEJEDM_02150 7.7e-24 yueI S Protein of unknown function (DUF1694)
MMAEJEDM_02151 3.4e-188 rarA L recombination factor protein RarA
MMAEJEDM_02153 3.2e-73 usp6 T universal stress protein
MMAEJEDM_02154 1.5e-52 tag 3.2.2.20 L glycosylase
MMAEJEDM_02155 1.3e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MMAEJEDM_02156 3.8e-124 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MMAEJEDM_02158 2e-75 yviA S Protein of unknown function (DUF421)
MMAEJEDM_02159 2e-26 S Protein of unknown function (DUF3290)
MMAEJEDM_02160 1.5e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
MMAEJEDM_02161 2.3e-295 S membrane
MMAEJEDM_02162 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MMAEJEDM_02163 1.4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
MMAEJEDM_02164 2.9e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MMAEJEDM_02165 1.5e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MMAEJEDM_02167 4.1e-16
MMAEJEDM_02168 2.5e-200 oatA I Acyltransferase
MMAEJEDM_02169 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MMAEJEDM_02170 1.6e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MMAEJEDM_02171 2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MMAEJEDM_02174 6.7e-42 S Phosphoesterase
MMAEJEDM_02175 3.6e-71 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MMAEJEDM_02176 1.1e-60 yslB S Protein of unknown function (DUF2507)
MMAEJEDM_02177 9.9e-41 trxA O Belongs to the thioredoxin family
MMAEJEDM_02178 6.5e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MMAEJEDM_02179 2.9e-14 cvpA S Colicin V production protein
MMAEJEDM_02180 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MMAEJEDM_02181 2.1e-32 yrzB S Belongs to the UPF0473 family
MMAEJEDM_02182 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MMAEJEDM_02183 2.1e-36 yrzL S Belongs to the UPF0297 family
MMAEJEDM_02184 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MMAEJEDM_02185 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MMAEJEDM_02186 9.4e-122 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MMAEJEDM_02187 7.5e-13
MMAEJEDM_02188 3.9e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MMAEJEDM_02189 1.6e-65 yrjD S LUD domain
MMAEJEDM_02190 2.1e-245 lutB C 4Fe-4S dicluster domain
MMAEJEDM_02191 9e-117 lutA C Cysteine-rich domain
MMAEJEDM_02192 2e-208 yfnA E Amino Acid
MMAEJEDM_02194 4.3e-61 uspA T universal stress protein
MMAEJEDM_02198 3.8e-13 infB M YSIRK type signal peptide
MMAEJEDM_02199 9.3e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MMAEJEDM_02200 6.2e-210 glnP P ABC transporter
MMAEJEDM_02202 1.7e-92 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
MMAEJEDM_02204 7.3e-79 L Replication protein
MMAEJEDM_02205 3.7e-90 yunF F Protein of unknown function DUF72
MMAEJEDM_02206 1.7e-156 nrnB S DHHA1 domain
MMAEJEDM_02207 4.8e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MMAEJEDM_02208 3.8e-59
MMAEJEDM_02209 5.4e-92 sip L Phage integrase, N-terminal SAM-like domain
MMAEJEDM_02210 3e-15 S Hypothetical protein (DUF2513)
MMAEJEDM_02212 1.1e-16 E Zn peptidase
MMAEJEDM_02213 1.3e-28 S sequence-specific DNA binding
MMAEJEDM_02214 1.2e-102 pgm3 G phosphoglycerate mutase
MMAEJEDM_02215 3.6e-56 S CAAX protease self-immunity
MMAEJEDM_02216 2.4e-46 C Flavodoxin
MMAEJEDM_02217 1.1e-55 yphH S Cupin domain
MMAEJEDM_02218 1.4e-45 yphJ 4.1.1.44 S decarboxylase
MMAEJEDM_02220 9.6e-09 N Bacterial Ig-like domain 2
MMAEJEDM_02225 3.8e-40 S Bacteriophage holin family
MMAEJEDM_02228 2.1e-11 M Host cell surface-exposed lipoprotein
MMAEJEDM_02229 4.4e-15 E IrrE N-terminal-like domain
MMAEJEDM_02230 2.9e-29 K Helix-turn-helix XRE-family like proteins
MMAEJEDM_02231 2.6e-91 T Calcineurin-like phosphoesterase superfamily domain
MMAEJEDM_02232 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
MMAEJEDM_02233 2.7e-30 P Heavy-metal-associated domain
MMAEJEDM_02234 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MMAEJEDM_02236 1e-80 L PFAM Integrase catalytic region
MMAEJEDM_02237 2.9e-128 EGP Major Facilitator Superfamily
MMAEJEDM_02238 1.1e-98 EGP Major Facilitator Superfamily
MMAEJEDM_02239 6.3e-72 K Transcriptional regulator, LysR family
MMAEJEDM_02240 4.7e-138 G Xylose isomerase-like TIM barrel
MMAEJEDM_02241 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
MMAEJEDM_02242 8e-217 1.3.5.4 C FAD binding domain
MMAEJEDM_02243 8.4e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MMAEJEDM_02244 4.5e-71 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MMAEJEDM_02245 2.4e-142 xerS L Phage integrase family
MMAEJEDM_02249 3.1e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MMAEJEDM_02250 3.6e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
MMAEJEDM_02251 6.4e-76 desR K helix_turn_helix, Lux Regulon
MMAEJEDM_02252 2.4e-57 salK 2.7.13.3 T Histidine kinase
MMAEJEDM_02253 1.1e-53 yvfS V ABC-2 type transporter
MMAEJEDM_02254 6.2e-80 yvfR V ABC transporter
MMAEJEDM_02255 4.6e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MMAEJEDM_02256 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MMAEJEDM_02257 4.2e-29
MMAEJEDM_02258 1.6e-61 sip L Belongs to the 'phage' integrase family
MMAEJEDM_02259 5e-07
MMAEJEDM_02262 4.2e-29 M CHAP domain
MMAEJEDM_02264 2.2e-191 U type IV secretory pathway VirB4
MMAEJEDM_02265 3.5e-27
MMAEJEDM_02267 1.2e-77
MMAEJEDM_02268 1.7e-219 U TraM recognition site of TraD and TraG
MMAEJEDM_02272 2.2e-148 clpB O Belongs to the ClpA ClpB family
MMAEJEDM_02275 5.8e-167 topA2 5.99.1.2 G Topoisomerase IA
MMAEJEDM_02276 5.2e-42 L Protein of unknown function (DUF3991)
MMAEJEDM_02277 4.5e-69
MMAEJEDM_02279 9.8e-44
MMAEJEDM_02280 4e-130 S AAA domain, putative AbiEii toxin, Type IV TA system
MMAEJEDM_02281 6.7e-89 pac DM Glucan-binding protein C

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)