ORF_ID e_value Gene_name EC_number CAZy COGs Description
NGNKGMEN_00003 3.9e-14 S Phage portal protein, SPP1 Gp6-like
NGNKGMEN_00005 1.2e-44 K Copper transport repressor CopY TcrY
NGNKGMEN_00006 6.1e-60 T Belongs to the universal stress protein A family
NGNKGMEN_00007 2.6e-41 K Bacterial regulatory proteins, tetR family
NGNKGMEN_00008 1.1e-56 K transcriptional
NGNKGMEN_00009 8.1e-72 mleR K LysR family
NGNKGMEN_00010 7e-247 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NGNKGMEN_00011 3.9e-128 mleP S Sodium Bile acid symporter family
NGNKGMEN_00012 3.2e-64 S ECF transporter, substrate-specific component
NGNKGMEN_00013 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
NGNKGMEN_00014 3.3e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NGNKGMEN_00015 1.7e-193 pbuX F xanthine permease
NGNKGMEN_00016 3.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NGNKGMEN_00017 8.1e-256 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NGNKGMEN_00018 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
NGNKGMEN_00019 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NGNKGMEN_00020 8.4e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NGNKGMEN_00021 1.6e-159 mgtE P Acts as a magnesium transporter
NGNKGMEN_00023 1.7e-40
NGNKGMEN_00024 2.8e-34 K GNAT family
NGNKGMEN_00025 6.4e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NGNKGMEN_00026 2.4e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NGNKGMEN_00027 1.1e-41 O ADP-ribosylglycohydrolase
NGNKGMEN_00028 6.1e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NGNKGMEN_00029 8.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NGNKGMEN_00030 2.6e-163 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NGNKGMEN_00031 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
NGNKGMEN_00032 9.4e-195 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
NGNKGMEN_00033 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NGNKGMEN_00034 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
NGNKGMEN_00035 3.4e-24 S Domain of unknown function (DUF4828)
NGNKGMEN_00036 1.6e-127 mocA S Oxidoreductase
NGNKGMEN_00037 2e-159 yfmL L DEAD DEAH box helicase
NGNKGMEN_00038 2e-20 S Domain of unknown function (DUF3284)
NGNKGMEN_00040 1e-279 kup P Transport of potassium into the cell
NGNKGMEN_00041 9.4e-101 malR K Transcriptional regulator, LacI family
NGNKGMEN_00042 4.3e-213 malT G Transporter, major facilitator family protein
NGNKGMEN_00043 1e-78 galM 5.1.3.3 G Aldose 1-epimerase
NGNKGMEN_00044 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NGNKGMEN_00045 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NGNKGMEN_00046 1.5e-243 E Amino acid permease
NGNKGMEN_00047 3.8e-08 E Amino acid permease
NGNKGMEN_00048 2.3e-181 pepS E Thermophilic metalloprotease (M29)
NGNKGMEN_00049 4.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NGNKGMEN_00050 1.8e-70 K Sugar-specific transcriptional regulator TrmB
NGNKGMEN_00051 1.6e-54 S Sulfite exporter TauE/SafE
NGNKGMEN_00052 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NGNKGMEN_00053 7.2e-53 perR P Belongs to the Fur family
NGNKGMEN_00054 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
NGNKGMEN_00055 7e-94 sbcC L Putative exonuclease SbcCD, C subunit
NGNKGMEN_00056 3.7e-114 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NGNKGMEN_00057 2.1e-36 M LysM domain protein
NGNKGMEN_00058 1.1e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NGNKGMEN_00059 1.8e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NGNKGMEN_00060 1e-34 ygfC K Bacterial regulatory proteins, tetR family
NGNKGMEN_00061 7.7e-101 hrtB V ABC transporter permease
NGNKGMEN_00062 3.4e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NGNKGMEN_00063 5.2e-67 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NGNKGMEN_00064 0.0 helD 3.6.4.12 L DNA helicase
NGNKGMEN_00065 1.2e-245 yjbQ P TrkA C-terminal domain protein
NGNKGMEN_00066 1.8e-30
NGNKGMEN_00067 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
NGNKGMEN_00068 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NGNKGMEN_00069 6.5e-126 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NGNKGMEN_00070 2.2e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NGNKGMEN_00071 1.3e-109 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NGNKGMEN_00072 6.1e-101 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NGNKGMEN_00073 1.4e-52 rplQ J Ribosomal protein L17
NGNKGMEN_00074 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NGNKGMEN_00075 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NGNKGMEN_00076 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NGNKGMEN_00077 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NGNKGMEN_00078 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NGNKGMEN_00079 3.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NGNKGMEN_00080 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NGNKGMEN_00081 1e-67 rplO J Binds to the 23S rRNA
NGNKGMEN_00082 2.1e-22 rpmD J Ribosomal protein L30
NGNKGMEN_00083 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NGNKGMEN_00084 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NGNKGMEN_00085 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NGNKGMEN_00086 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NGNKGMEN_00087 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NGNKGMEN_00088 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NGNKGMEN_00089 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NGNKGMEN_00090 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NGNKGMEN_00091 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NGNKGMEN_00092 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
NGNKGMEN_00093 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NGNKGMEN_00094 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NGNKGMEN_00095 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NGNKGMEN_00096 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NGNKGMEN_00097 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NGNKGMEN_00098 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NGNKGMEN_00099 1e-100 rplD J Forms part of the polypeptide exit tunnel
NGNKGMEN_00100 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NGNKGMEN_00101 3.7e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NGNKGMEN_00102 6.2e-166 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NGNKGMEN_00103 6.5e-79 K rpiR family
NGNKGMEN_00104 2.2e-53 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NGNKGMEN_00105 8.5e-147 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
NGNKGMEN_00106 4.9e-21 K Acetyltransferase (GNAT) domain
NGNKGMEN_00107 6.4e-182 steT E amino acid
NGNKGMEN_00108 9.6e-78 glnP P ABC transporter permease
NGNKGMEN_00109 1.2e-85 gluC P ABC transporter permease
NGNKGMEN_00110 1.1e-99 glnH ET ABC transporter
NGNKGMEN_00111 3.3e-103 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NGNKGMEN_00112 1.3e-09
NGNKGMEN_00113 5e-98
NGNKGMEN_00114 3.1e-09 3.2.1.14 GH18
NGNKGMEN_00115 2.4e-53 zur P Belongs to the Fur family
NGNKGMEN_00116 3.7e-212 yfnA E Amino Acid
NGNKGMEN_00117 9.2e-104 tatD L hydrolase, TatD family
NGNKGMEN_00118 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NGNKGMEN_00119 7e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NGNKGMEN_00120 1.2e-22 veg S Biofilm formation stimulator VEG
NGNKGMEN_00121 8e-90 S Alpha/beta hydrolase of unknown function (DUF915)
NGNKGMEN_00122 1.7e-138 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
NGNKGMEN_00123 6.6e-46 argR K Regulates arginine biosynthesis genes
NGNKGMEN_00124 9e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NGNKGMEN_00125 3e-155 amtB P ammonium transporter
NGNKGMEN_00126 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
NGNKGMEN_00127 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NGNKGMEN_00128 2.9e-149 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NGNKGMEN_00129 2.9e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NGNKGMEN_00130 1.2e-103 pfoS S Phosphotransferase system, EIIC
NGNKGMEN_00132 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NGNKGMEN_00133 2.5e-44 adhR K helix_turn_helix, mercury resistance
NGNKGMEN_00134 5.2e-137 purR 2.4.2.7 F pur operon repressor
NGNKGMEN_00135 8.9e-45 EGP Transmembrane secretion effector
NGNKGMEN_00136 5.1e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NGNKGMEN_00137 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NGNKGMEN_00138 1.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NGNKGMEN_00140 5.8e-112 dkg S reductase
NGNKGMEN_00141 1.3e-24
NGNKGMEN_00142 3e-78 2.4.2.3 F Phosphorylase superfamily
NGNKGMEN_00143 1.4e-290 ybiT S ABC transporter, ATP-binding protein
NGNKGMEN_00144 1.5e-62 bCE_4747 S Beta-lactamase superfamily domain
NGNKGMEN_00145 1.3e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NGNKGMEN_00146 3e-124 S overlaps another CDS with the same product name
NGNKGMEN_00147 2.9e-86 S overlaps another CDS with the same product name
NGNKGMEN_00149 6e-57 spoVK O ATPase family associated with various cellular activities (AAA)
NGNKGMEN_00150 3.6e-24 L Eco57I restriction-modification methylase
NGNKGMEN_00151 1.4e-70 L recombinase activity
NGNKGMEN_00152 4.1e-73
NGNKGMEN_00153 2.8e-22
NGNKGMEN_00154 1.2e-70 ydcZ S Putative inner membrane exporter, YdcZ
NGNKGMEN_00155 1.7e-87 S hydrolase
NGNKGMEN_00156 2.5e-205 ywfO S HD domain protein
NGNKGMEN_00157 4.4e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
NGNKGMEN_00158 1.8e-32 ywiB S Domain of unknown function (DUF1934)
NGNKGMEN_00159 9.9e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NGNKGMEN_00160 3.3e-289 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NGNKGMEN_00163 1.6e-201 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NGNKGMEN_00164 4.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NGNKGMEN_00165 1.4e-40 rpmE2 J Ribosomal protein L31
NGNKGMEN_00166 8e-61
NGNKGMEN_00167 8.8e-50 yugI 5.3.1.9 J general stress protein
NGNKGMEN_00168 2.7e-95 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NGNKGMEN_00169 8.8e-92 dedA S SNARE associated Golgi protein
NGNKGMEN_00170 3.5e-32 S Protein of unknown function (DUF1461)
NGNKGMEN_00171 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NGNKGMEN_00172 1.9e-53 yutD S Protein of unknown function (DUF1027)
NGNKGMEN_00173 1.7e-57 S Calcineurin-like phosphoesterase
NGNKGMEN_00174 2.3e-182 cycA E Amino acid permease
NGNKGMEN_00175 6.9e-72 ytxK 2.1.1.72 L N-6 DNA Methylase
NGNKGMEN_00177 4.1e-11 S Putative Competence protein ComGF
NGNKGMEN_00179 1.5e-13
NGNKGMEN_00180 1.8e-22 comGC U competence protein ComGC
NGNKGMEN_00181 3.9e-112 M lysozyme activity
NGNKGMEN_00182 2e-19 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NGNKGMEN_00186 9.7e-183 sidC GT2,GT4 LM DNA recombination
NGNKGMEN_00187 1.6e-34
NGNKGMEN_00188 3.6e-216 M Phage tail tape measure protein TP901
NGNKGMEN_00189 7.1e-19
NGNKGMEN_00190 1.5e-33
NGNKGMEN_00191 1.1e-38 S Phage tail tube protein, TTP
NGNKGMEN_00192 7.1e-38
NGNKGMEN_00193 1.1e-55
NGNKGMEN_00194 4.3e-32
NGNKGMEN_00195 2.9e-19
NGNKGMEN_00197 2e-130 S Phage major capsid protein E
NGNKGMEN_00198 1.4e-27
NGNKGMEN_00199 2.7e-08 S Domain of unknown function (DUF4355)
NGNKGMEN_00200 5e-109 S Phage Mu protein F like protein
NGNKGMEN_00201 2.9e-08 S Cysteine protease Prp
NGNKGMEN_00202 3.5e-160 S Phage portal protein, SPP1 Gp6-like
NGNKGMEN_00203 1.2e-177 ps334 S Terminase-like family
NGNKGMEN_00204 2.3e-36 L transposase activity
NGNKGMEN_00205 1.7e-20
NGNKGMEN_00206 8.9e-16 capL M UDP-N-acetyl-D-mannosamine dehydrogenase activity
NGNKGMEN_00211 2.2e-30
NGNKGMEN_00212 1.4e-68 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NGNKGMEN_00213 1.1e-116 L Phage integrase family
NGNKGMEN_00215 3.8e-59 L Belongs to the 'phage' integrase family
NGNKGMEN_00216 3.8e-28 S HNH endonuclease
NGNKGMEN_00217 2e-07
NGNKGMEN_00221 2e-40 S Protein of unknown function (DUF1064)
NGNKGMEN_00223 1.5e-79
NGNKGMEN_00224 8.4e-27
NGNKGMEN_00225 3.2e-16 S sequence-specific DNA binding
NGNKGMEN_00227 1.2e-19
NGNKGMEN_00228 5.7e-124 dnaB 3.6.4.12 L DnaB-like helicase C terminal domain
NGNKGMEN_00229 3.7e-27 S calcium ion binding
NGNKGMEN_00230 2.2e-12 K Cro/C1-type HTH DNA-binding domain
NGNKGMEN_00231 5e-68 S Putative HNHc nuclease
NGNKGMEN_00232 3.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
NGNKGMEN_00233 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NGNKGMEN_00234 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
NGNKGMEN_00235 6.3e-109 spo0J K Belongs to the ParB family
NGNKGMEN_00236 6.5e-118 soj D Sporulation initiation inhibitor
NGNKGMEN_00237 1.7e-82 noc K Belongs to the ParB family
NGNKGMEN_00238 6.2e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NGNKGMEN_00239 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NGNKGMEN_00240 2.1e-108 3.1.4.46 C phosphodiesterase
NGNKGMEN_00241 0.0 pacL 3.6.3.8 P P-type ATPase
NGNKGMEN_00242 1.7e-156 L Probable transposase
NGNKGMEN_00243 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
NGNKGMEN_00244 5.2e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NGNKGMEN_00246 6.2e-64 srtA 3.4.22.70 M sortase family
NGNKGMEN_00247 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NGNKGMEN_00248 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NGNKGMEN_00249 1.1e-33
NGNKGMEN_00250 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NGNKGMEN_00251 1e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NGNKGMEN_00252 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NGNKGMEN_00253 3.6e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
NGNKGMEN_00254 1.1e-39 ybjQ S Belongs to the UPF0145 family
NGNKGMEN_00255 2.5e-08
NGNKGMEN_00256 6.1e-96 V ABC transporter, ATP-binding protein
NGNKGMEN_00257 1.1e-41 gntR1 K Transcriptional regulator, GntR family
NGNKGMEN_00258 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
NGNKGMEN_00259 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NGNKGMEN_00260 1.1e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
NGNKGMEN_00261 2.2e-107 terC P Integral membrane protein TerC family
NGNKGMEN_00262 1.6e-38 K Transcriptional regulator
NGNKGMEN_00263 2e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NGNKGMEN_00264 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NGNKGMEN_00265 4.5e-102 tcyB E ABC transporter
NGNKGMEN_00267 2.5e-44 M Glycosyl hydrolases family 25
NGNKGMEN_00268 1.4e-187 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NGNKGMEN_00269 2.9e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NGNKGMEN_00270 2e-209 mtlR K Mga helix-turn-helix domain
NGNKGMEN_00271 4.9e-176 yjcE P Sodium proton antiporter
NGNKGMEN_00274 3e-246 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NGNKGMEN_00275 1e-32 asp3 S Accessory Sec system protein Asp3
NGNKGMEN_00276 4.4e-105 asp2 3.4.11.5 S Accessory Sec system protein Asp2
NGNKGMEN_00277 9.2e-90 asp1 S Accessory Sec system protein Asp1
NGNKGMEN_00278 8.7e-64 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
NGNKGMEN_00279 3.3e-134 S interspecies interaction between organisms
NGNKGMEN_00280 4.7e-207 G glycerol-3-phosphate transporter
NGNKGMEN_00281 9.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NGNKGMEN_00282 9.6e-146 htrA 3.4.21.107 O serine protease
NGNKGMEN_00283 4.9e-116 vicX 3.1.26.11 S domain protein
NGNKGMEN_00284 6.8e-30 yyaQ S YjbR
NGNKGMEN_00285 2.1e-79 yycI S YycH protein
NGNKGMEN_00286 1.3e-102 yycH S YycH protein
NGNKGMEN_00287 1.5e-272 vicK 2.7.13.3 T Histidine kinase
NGNKGMEN_00288 9e-114 K response regulator
NGNKGMEN_00289 3.3e-09 bta 1.8.1.8 CO transport accessory protein
NGNKGMEN_00290 4.6e-153 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NGNKGMEN_00291 1.9e-172 dltB M MBOAT, membrane-bound O-acyltransferase family
NGNKGMEN_00293 4.7e-106 yxeH S hydrolase
NGNKGMEN_00295 3.3e-96 S Domain of unknown function DUF87
NGNKGMEN_00297 4.1e-229 V ABC transporter transmembrane region
NGNKGMEN_00298 4e-216 XK27_09600 V ABC transporter, ATP-binding protein
NGNKGMEN_00299 9.3e-32 K Transcriptional regulator, MarR family
NGNKGMEN_00300 4.9e-172 S Putative peptidoglycan binding domain
NGNKGMEN_00302 2.1e-24 relB L RelB antitoxin
NGNKGMEN_00303 1.4e-61 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NGNKGMEN_00304 2.3e-140 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
NGNKGMEN_00305 1.7e-178 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NGNKGMEN_00306 8.6e-109 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NGNKGMEN_00307 6e-223 pepF E Oligopeptidase F
NGNKGMEN_00308 3.7e-96 yicL EG EamA-like transporter family
NGNKGMEN_00309 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NGNKGMEN_00310 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NGNKGMEN_00311 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NGNKGMEN_00312 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NGNKGMEN_00313 6.9e-37
NGNKGMEN_00314 1.8e-114 S N-acetylmuramoyl-L-alanine amidase activity
NGNKGMEN_00315 1.1e-14 S Bacteriophage holin family
NGNKGMEN_00321 1.6e-11 N Bacterial Ig-like domain 2
NGNKGMEN_00322 4.2e-27 S Calcineurin-like phosphoesterase
NGNKGMEN_00324 1.6e-122 rny D peptidase
NGNKGMEN_00325 3e-76 S Phage tail protein
NGNKGMEN_00326 0.0 M Phage tail tape measure protein TP901
NGNKGMEN_00328 5.3e-53 S Phage tail assembly chaperone proteins, TAC
NGNKGMEN_00329 1e-125 S Phage tail tube protein
NGNKGMEN_00330 1.6e-64 S Protein of unknown function (DUF806)
NGNKGMEN_00331 5.7e-55 S Bacteriophage HK97-gp10, putative tail-component
NGNKGMEN_00332 4.6e-58 S Phage head-tail joining protein
NGNKGMEN_00333 2.8e-22 S Phage gp6-like head-tail connector protein
NGNKGMEN_00334 4.4e-222 S Phage capsid family
NGNKGMEN_00335 9.9e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NGNKGMEN_00336 6.1e-208 S Phage portal protein
NGNKGMEN_00338 0.0 S Phage Terminase
NGNKGMEN_00339 3.6e-82 L Phage terminase, small subunit
NGNKGMEN_00340 6.3e-88 L HNH nucleases
NGNKGMEN_00342 1.5e-27 arpU S Phage transcriptional regulator, ArpU family
NGNKGMEN_00347 1.4e-41 S Protein of unknown function (DUF1064)
NGNKGMEN_00349 3.8e-36 L Psort location Cytoplasmic, score 8.96
NGNKGMEN_00353 6.9e-18
NGNKGMEN_00354 1.5e-124 dnaB 3.6.4.12 L DnaB-like helicase C terminal domain
NGNKGMEN_00355 1.4e-31 L Helix-turn-helix domain
NGNKGMEN_00356 1.5e-89 S Putative HNHc nuclease
NGNKGMEN_00357 9.4e-37 S Protein of unknown function (DUF669)
NGNKGMEN_00358 2.8e-67 S AAA domain
NGNKGMEN_00360 2.7e-25 S Bacteriophage Mu Gam like protein
NGNKGMEN_00366 1.5e-48 K ORF6N domain
NGNKGMEN_00367 1.5e-24 XK27_07105 K Helix-turn-helix XRE-family like proteins
NGNKGMEN_00368 1.2e-23 yvaO K Helix-turn-helix XRE-family like proteins
NGNKGMEN_00369 3.1e-29 E Zn peptidase
NGNKGMEN_00370 1.9e-20
NGNKGMEN_00372 2.5e-28 S Short C-terminal domain
NGNKGMEN_00373 2e-18 L nuclease
NGNKGMEN_00374 1.5e-13
NGNKGMEN_00375 3.5e-144 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NGNKGMEN_00376 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NGNKGMEN_00377 1.1e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NGNKGMEN_00378 7.1e-161 camS S sex pheromone
NGNKGMEN_00379 1.7e-37 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NGNKGMEN_00380 1.6e-234 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NGNKGMEN_00381 5.6e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NGNKGMEN_00382 9.8e-146 yegS 2.7.1.107 G Lipid kinase
NGNKGMEN_00383 7.6e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NGNKGMEN_00384 6.4e-36 3.1.21.3 V Type I restriction modification DNA specificity domain
NGNKGMEN_00386 2e-120 L Mrr N-terminal domain
NGNKGMEN_00387 7.3e-18
NGNKGMEN_00388 3.3e-222 mod 2.1.1.72, 3.1.21.5 L DNA methylase
NGNKGMEN_00389 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
NGNKGMEN_00390 1.1e-210 K DNA binding
NGNKGMEN_00391 0.0 L helicase activity
NGNKGMEN_00392 1.5e-103 S Domain of unknown function (DUF4343)
NGNKGMEN_00393 4.9e-56 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
NGNKGMEN_00394 3.1e-44 S Domain of unknown function (DUF3841)
NGNKGMEN_00395 1.6e-174 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
NGNKGMEN_00396 6.6e-70 tlpA2 L Transposase IS200 like
NGNKGMEN_00397 2.4e-178 L transposase, IS605 OrfB family
NGNKGMEN_00398 1.6e-129 C Oxidoreductase
NGNKGMEN_00399 6.7e-72 ywlG S Belongs to the UPF0340 family
NGNKGMEN_00400 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NGNKGMEN_00401 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NGNKGMEN_00402 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NGNKGMEN_00403 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NGNKGMEN_00404 1e-27 ysxB J Cysteine protease Prp
NGNKGMEN_00405 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
NGNKGMEN_00408 1.2e-65 S RRXRR protein
NGNKGMEN_00413 3.7e-16 K DNA-templated transcription, initiation
NGNKGMEN_00415 1.5e-66 H Methyltransferase domain
NGNKGMEN_00416 1.4e-77 cps2D 5.1.3.2 M RmlD substrate binding domain
NGNKGMEN_00417 3.3e-41 wecD M Acetyltransferase (GNAT) family
NGNKGMEN_00419 1.8e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
NGNKGMEN_00420 3.4e-41 S Protein of unknown function (DUF1211)
NGNKGMEN_00422 0.0 L helicase
NGNKGMEN_00423 2.7e-66 1.1.1.1 C Zinc-binding dehydrogenase
NGNKGMEN_00424 2.4e-31 S CHY zinc finger
NGNKGMEN_00425 9.5e-40 K Transcriptional regulator
NGNKGMEN_00426 5.2e-84 qorB 1.6.5.2 GM NmrA-like family
NGNKGMEN_00427 1.4e-08
NGNKGMEN_00428 7.9e-43 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NGNKGMEN_00429 6.5e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NGNKGMEN_00430 3.6e-81
NGNKGMEN_00431 4.4e-82 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NGNKGMEN_00432 1.8e-113 yitU 3.1.3.104 S hydrolase
NGNKGMEN_00433 1.9e-60 speG J Acetyltransferase (GNAT) domain
NGNKGMEN_00434 7e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NGNKGMEN_00435 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NGNKGMEN_00436 1.2e-205 pipD E Dipeptidase
NGNKGMEN_00437 2.3e-45
NGNKGMEN_00438 1.2e-64 K helix_turn_helix, arabinose operon control protein
NGNKGMEN_00439 6e-44 S Membrane
NGNKGMEN_00440 0.0 rafA 3.2.1.22 G alpha-galactosidase
NGNKGMEN_00441 1.9e-93 L Helicase C-terminal domain protein
NGNKGMEN_00442 6.2e-42 L Helicase C-terminal domain protein
NGNKGMEN_00444 3.6e-145 pbuO_1 S Permease family
NGNKGMEN_00445 1.4e-54
NGNKGMEN_00446 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NGNKGMEN_00447 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NGNKGMEN_00448 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NGNKGMEN_00449 4.8e-45 nrdI F NrdI Flavodoxin like
NGNKGMEN_00450 2.7e-27 nrdH O Glutaredoxin
NGNKGMEN_00451 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
NGNKGMEN_00452 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NGNKGMEN_00453 6.7e-211 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NGNKGMEN_00454 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NGNKGMEN_00455 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NGNKGMEN_00456 1.3e-28 yaaL S Protein of unknown function (DUF2508)
NGNKGMEN_00457 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NGNKGMEN_00458 2.3e-83 holB 2.7.7.7 L DNA polymerase III
NGNKGMEN_00459 1.4e-40 yabA L Involved in initiation control of chromosome replication
NGNKGMEN_00460 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NGNKGMEN_00461 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
NGNKGMEN_00462 2.7e-140 ansA 3.5.1.1 EJ Asparaginase
NGNKGMEN_00463 2.8e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NGNKGMEN_00464 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NGNKGMEN_00465 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NGNKGMEN_00466 1.2e-253 uup S ABC transporter, ATP-binding protein
NGNKGMEN_00467 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NGNKGMEN_00468 2.4e-33 S CAAX protease self-immunity
NGNKGMEN_00469 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NGNKGMEN_00470 1.8e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NGNKGMEN_00471 4.3e-269 aha1 P COG COG0474 Cation transport ATPase
NGNKGMEN_00472 4.1e-296 ydaO E amino acid
NGNKGMEN_00473 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
NGNKGMEN_00474 3.5e-127 comFA L Helicase C-terminal domain protein
NGNKGMEN_00475 1e-45 comFC S Competence protein
NGNKGMEN_00477 9.3e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NGNKGMEN_00478 1.2e-135 pfoS S Phosphotransferase system, EIIC
NGNKGMEN_00479 1.1e-27 K Helix-turn-helix XRE-family like proteins
NGNKGMEN_00480 1.1e-118 repE K Primase C terminal 1 (PriCT-1)
NGNKGMEN_00487 7.5e-18 hicA S HicA toxin of bacterial toxin-antitoxin,
NGNKGMEN_00488 2.4e-15 S HicB family
NGNKGMEN_00493 2.5e-223 E ABC transporter, substratebinding protein
NGNKGMEN_00494 8.1e-116 sufC O FeS assembly ATPase SufC
NGNKGMEN_00495 1.2e-142 sufD O FeS assembly protein SufD
NGNKGMEN_00496 4.8e-147 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NGNKGMEN_00497 1.4e-40 nifU C SUF system FeS assembly protein, NifU family
NGNKGMEN_00498 1.2e-239 sufB O assembly protein SufB
NGNKGMEN_00499 7.3e-45 S VIT family
NGNKGMEN_00500 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
NGNKGMEN_00501 4.4e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NGNKGMEN_00502 2.6e-110 rssA S Phospholipase, patatin family
NGNKGMEN_00503 8.2e-16
NGNKGMEN_00505 5.7e-39
NGNKGMEN_00506 1e-197 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NGNKGMEN_00510 3.5e-87 S Fic/DOC family
NGNKGMEN_00511 6.6e-11 S sequence-specific DNA binding
NGNKGMEN_00512 2.3e-11 3.4.21.88 K Peptidase S24-like
NGNKGMEN_00523 5.8e-21 S Replication initiator protein A (RepA) N-terminus
NGNKGMEN_00528 2.7e-07
NGNKGMEN_00531 2.2e-23 K SIR2-like domain
NGNKGMEN_00538 7.5e-20
NGNKGMEN_00539 3.8e-12 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
NGNKGMEN_00543 1.3e-61 ruvB 3.6.4.12 L four-way junction helicase activity
NGNKGMEN_00544 4.8e-43 gepA S Protein of unknown function (DUF4065)
NGNKGMEN_00545 8.6e-34
NGNKGMEN_00546 3.3e-12 chpR T PFAM SpoVT AbrB
NGNKGMEN_00547 4.4e-29 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NGNKGMEN_00548 7.4e-79 S Fic/DOC family
NGNKGMEN_00549 4.2e-206 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction-modification system methyltransferase subunit
NGNKGMEN_00551 1.3e-25 D nuclear chromosome segregation
NGNKGMEN_00552 2e-08
NGNKGMEN_00553 5.3e-106 L Belongs to the 'phage' integrase family
NGNKGMEN_00555 8.1e-89 pac DM Glucan-binding protein C
NGNKGMEN_00556 4e-130 S AAA domain, putative AbiEii toxin, Type IV TA system
NGNKGMEN_00557 9.8e-44
NGNKGMEN_00559 4.5e-69
NGNKGMEN_00560 5.2e-42 L Protein of unknown function (DUF3991)
NGNKGMEN_00561 4.5e-167 topA2 5.99.1.2 G Topoisomerase IA
NGNKGMEN_00564 2.9e-148 clpB O Belongs to the ClpA ClpB family
NGNKGMEN_00568 2.9e-219 U TraM recognition site of TraD and TraG
NGNKGMEN_00569 3.9e-76
NGNKGMEN_00571 4.6e-27
NGNKGMEN_00572 2.9e-191 U type IV secretory pathway VirB4
NGNKGMEN_00574 2.9e-30 M CHAP domain
NGNKGMEN_00577 6.5e-07
NGNKGMEN_00578 6.7e-63 sip L Belongs to the 'phage' integrase family
NGNKGMEN_00579 4.2e-29
NGNKGMEN_00580 2.3e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NGNKGMEN_00581 4.6e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NGNKGMEN_00582 6.2e-80 yvfR V ABC transporter
NGNKGMEN_00583 1.1e-53 yvfS V ABC-2 type transporter
NGNKGMEN_00584 2.4e-57 salK 2.7.13.3 T Histidine kinase
NGNKGMEN_00585 6.4e-76 desR K helix_turn_helix, Lux Regulon
NGNKGMEN_00586 3.6e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
NGNKGMEN_00587 3.1e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NGNKGMEN_00591 2.4e-142 xerS L Phage integrase family
NGNKGMEN_00592 4.5e-71 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NGNKGMEN_00593 8.4e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NGNKGMEN_00594 1e-216 1.3.5.4 C FAD binding domain
NGNKGMEN_00595 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
NGNKGMEN_00596 1.6e-138 G Xylose isomerase-like TIM barrel
NGNKGMEN_00597 1.7e-72 K Transcriptional regulator, LysR family
NGNKGMEN_00598 6.3e-99 EGP Major Facilitator Superfamily
NGNKGMEN_00599 9.8e-129 EGP Major Facilitator Superfamily
NGNKGMEN_00600 1.8e-80 L PFAM Integrase catalytic region
NGNKGMEN_00602 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NGNKGMEN_00603 7e-31 P Heavy-metal-associated domain
NGNKGMEN_00605 1.8e-160 L transposase, IS605 OrfB family
NGNKGMEN_00606 4.3e-58 tlpA2 L Transposase IS200 like
NGNKGMEN_00607 3e-125 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NGNKGMEN_00608 5.4e-85 dps P Ferritin-like domain
NGNKGMEN_00609 1.1e-14 tnp L Transposase IS66 family
NGNKGMEN_00610 1.4e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
NGNKGMEN_00611 9e-102 qmcA O prohibitin homologues
NGNKGMEN_00612 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
NGNKGMEN_00613 0.0 O Belongs to the peptidase S8 family
NGNKGMEN_00614 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NGNKGMEN_00615 1.8e-08
NGNKGMEN_00616 2.4e-45 yjaB_1 K Acetyltransferase (GNAT) domain
NGNKGMEN_00617 4.1e-81 yitS S EDD domain protein, DegV family
NGNKGMEN_00618 5.6e-57 racA K Domain of unknown function (DUF1836)
NGNKGMEN_00619 7.2e-117 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NGNKGMEN_00620 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NGNKGMEN_00621 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
NGNKGMEN_00622 5.6e-69 dhaL 2.7.1.121 S Dak2
NGNKGMEN_00623 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NGNKGMEN_00624 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NGNKGMEN_00625 1.7e-61 K Bacterial regulatory proteins, tetR family
NGNKGMEN_00626 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
NGNKGMEN_00628 1.7e-111 endA F DNA RNA non-specific endonuclease
NGNKGMEN_00629 4.1e-75 XK27_02070 S Nitroreductase family
NGNKGMEN_00630 1.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
NGNKGMEN_00631 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
NGNKGMEN_00632 1.4e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
NGNKGMEN_00633 1.2e-221 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NGNKGMEN_00634 6.9e-214 G phosphotransferase system
NGNKGMEN_00635 9.7e-91 licT K CAT RNA binding domain
NGNKGMEN_00636 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NGNKGMEN_00637 2.7e-58 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
NGNKGMEN_00638 5.1e-77 azlC E branched-chain amino acid
NGNKGMEN_00639 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
NGNKGMEN_00640 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
NGNKGMEN_00641 1.6e-55 jag S R3H domain protein
NGNKGMEN_00642 9.1e-54 K Transcriptional regulator C-terminal region
NGNKGMEN_00643 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
NGNKGMEN_00644 3.1e-286 pepO 3.4.24.71 O Peptidase family M13
NGNKGMEN_00645 2.2e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
NGNKGMEN_00646 5.6e-08 S SdpI/YhfL protein family
NGNKGMEN_00647 7.8e-72 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NGNKGMEN_00648 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
NGNKGMEN_00649 1.2e-41 wecD K Acetyltransferase GNAT Family
NGNKGMEN_00651 1.1e-34 tetR K transcriptional regulator
NGNKGMEN_00654 1e-09 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NGNKGMEN_00657 5.4e-71 S AAA domain
NGNKGMEN_00659 1.6e-09 S Protein of unknown function (DUF1351)
NGNKGMEN_00666 3.4e-52 S ORF6C domain
NGNKGMEN_00667 2e-15
NGNKGMEN_00668 5.7e-25 K Helix-turn-helix XRE-family like proteins
NGNKGMEN_00669 5.7e-15 E IrrE N-terminal-like domain
NGNKGMEN_00670 1.4e-07 S Protein of unknown function (DUF4064)
NGNKGMEN_00671 4.2e-28 S Membrane
NGNKGMEN_00672 5.6e-123 S Recombinase
NGNKGMEN_00673 1.6e-58 comGB NU type II secretion system
NGNKGMEN_00674 2e-121 L ISXO2-like transposase domain
NGNKGMEN_00676 6.3e-22 3.1.21.3 V N-6 DNA Methylase
NGNKGMEN_00677 3.9e-104 3.1.21.3 L N-6 DNA Methylase
NGNKGMEN_00678 7.8e-27 comGB NU type II secretion system
NGNKGMEN_00679 2.3e-120 comGA NU Type II IV secretion system protein
NGNKGMEN_00680 1e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NGNKGMEN_00681 4.3e-119 yebC K Transcriptional regulatory protein
NGNKGMEN_00682 3.7e-42 S VanZ like family
NGNKGMEN_00683 1.3e-158 ccpA K catabolite control protein A
NGNKGMEN_00684 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NGNKGMEN_00685 3e-14
NGNKGMEN_00688 4.5e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NGNKGMEN_00689 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
NGNKGMEN_00690 2.3e-65 hly S protein, hemolysin III
NGNKGMEN_00691 2.8e-40 M1-874 K Domain of unknown function (DUF1836)
NGNKGMEN_00692 9.4e-84 S membrane
NGNKGMEN_00693 1.1e-79 S VIT family
NGNKGMEN_00694 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NGNKGMEN_00695 2.7e-56 P Plays a role in the regulation of phosphate uptake
NGNKGMEN_00696 1.1e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NGNKGMEN_00697 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NGNKGMEN_00698 3e-122 pstA P Phosphate transport system permease protein PstA
NGNKGMEN_00699 5.4e-119 pstC P probably responsible for the translocation of the substrate across the membrane
NGNKGMEN_00700 1.4e-97 pstS P Phosphate
NGNKGMEN_00701 3.9e-41 yjbH Q Thioredoxin
NGNKGMEN_00702 2.2e-158 XK27_08315 M Sulfatase
NGNKGMEN_00703 5.9e-106 S Bacterial membrane protein, YfhO
NGNKGMEN_00704 3.3e-82 M Dolichyl-phosphate-mannose-protein mannosyltransferase
NGNKGMEN_00705 2e-68 S Bacterial membrane protein, YfhO
NGNKGMEN_00706 3.6e-14
NGNKGMEN_00707 5.5e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NGNKGMEN_00708 2.6e-39 2.7.7.65 T phosphorelay sensor kinase activity
NGNKGMEN_00709 1.1e-157 XK27_09615 S reductase
NGNKGMEN_00710 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
NGNKGMEN_00711 2.1e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NGNKGMEN_00712 9.5e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NGNKGMEN_00713 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NGNKGMEN_00714 7.2e-31 gtcA S Teichoic acid glycosylation protein
NGNKGMEN_00715 1.9e-114 rfbJ M Glycosyl transferase family 2
NGNKGMEN_00716 1.4e-33 S Predicted membrane protein (DUF2142)
NGNKGMEN_00717 6.2e-80 L An automated process has identified a potential problem with this gene model
NGNKGMEN_00718 1e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NGNKGMEN_00719 3e-133 coaA 2.7.1.33 F Pantothenic acid kinase
NGNKGMEN_00720 2.2e-44 E GDSL-like Lipase/Acylhydrolase
NGNKGMEN_00721 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NGNKGMEN_00722 5.6e-190 glnPH2 P ABC transporter permease
NGNKGMEN_00723 1.6e-213 yjeM E Amino Acid
NGNKGMEN_00724 4.6e-33 yvdC S MazG nucleotide pyrophosphohydrolase domain
NGNKGMEN_00725 1.5e-137 tetA EGP Major facilitator Superfamily
NGNKGMEN_00726 8.4e-83 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NGNKGMEN_00727 1.4e-67 epsB M biosynthesis protein
NGNKGMEN_00728 5.4e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NGNKGMEN_00729 1.6e-19 S Psort location CytoplasmicMembrane, score 10.00
NGNKGMEN_00730 2.1e-81 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NGNKGMEN_00731 1.7e-92 cps2J S Polysaccharide biosynthesis protein
NGNKGMEN_00732 7.7e-36 S Bacterial transferase hexapeptide (six repeats)
NGNKGMEN_00733 9.2e-69 2.7.8.12 M Glycosyltransferase sugar-binding region containing DXD motif
NGNKGMEN_00734 4e-86 epsJ GT2 S Glycosyltransferase like family 2
NGNKGMEN_00735 7.1e-57 M Glycosyl transferases group 1
NGNKGMEN_00736 1.3e-146 GT2,GT4 S Haloacid dehalogenase-like hydrolase
NGNKGMEN_00737 1.6e-53 pssE S Glycosyltransferase family 28 C-terminal domain
NGNKGMEN_00738 3.9e-70 cpsF M Oligosaccharide biosynthesis protein Alg14 like
NGNKGMEN_00739 1.4e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NGNKGMEN_00740 3.3e-165 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NGNKGMEN_00741 7.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NGNKGMEN_00742 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NGNKGMEN_00743 1.7e-72 S Glycosyltransferase like family 2
NGNKGMEN_00744 2.1e-98 waaB GT4 M Glycosyl transferases group 1
NGNKGMEN_00745 1.7e-62 S Glycosyltransferase like family 2
NGNKGMEN_00746 5.8e-117 cps1D M Domain of unknown function (DUF4422)
NGNKGMEN_00747 5e-39 S CAAX protease self-immunity
NGNKGMEN_00748 9.1e-89 yvyE 3.4.13.9 S YigZ family
NGNKGMEN_00749 1.1e-57 S Haloacid dehalogenase-like hydrolase
NGNKGMEN_00750 7.6e-154 EGP Major facilitator Superfamily
NGNKGMEN_00752 7.6e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NGNKGMEN_00753 2.7e-27 adhR K helix_turn_helix, mercury resistance
NGNKGMEN_00754 1.5e-90 S NADPH-dependent FMN reductase
NGNKGMEN_00755 4e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NGNKGMEN_00756 1.5e-55 S ECF transporter, substrate-specific component
NGNKGMEN_00757 2.8e-95 znuB U ABC 3 transport family
NGNKGMEN_00758 1e-98 fhuC P ABC transporter
NGNKGMEN_00759 1.9e-102 psaA P Belongs to the bacterial solute-binding protein 9 family
NGNKGMEN_00760 1.5e-38
NGNKGMEN_00761 3.1e-30 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NGNKGMEN_00763 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NGNKGMEN_00764 2.7e-48 S Domain of unknown function (DUF956)
NGNKGMEN_00765 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NGNKGMEN_00766 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NGNKGMEN_00767 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NGNKGMEN_00768 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
NGNKGMEN_00769 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NGNKGMEN_00770 1.7e-259 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NGNKGMEN_00771 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NGNKGMEN_00772 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
NGNKGMEN_00773 4.8e-170 nusA K Participates in both transcription termination and antitermination
NGNKGMEN_00774 1.4e-39 ylxR K Protein of unknown function (DUF448)
NGNKGMEN_00775 6.9e-26 ylxQ J ribosomal protein
NGNKGMEN_00776 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NGNKGMEN_00777 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NGNKGMEN_00778 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NGNKGMEN_00779 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NGNKGMEN_00780 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NGNKGMEN_00781 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NGNKGMEN_00782 1.5e-274 dnaK O Heat shock 70 kDa protein
NGNKGMEN_00783 7.1e-158 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NGNKGMEN_00784 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NGNKGMEN_00786 2e-247 glnA 6.3.1.2 E glutamine synthetase
NGNKGMEN_00787 1.3e-45 glnR K Transcriptional regulator
NGNKGMEN_00788 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
NGNKGMEN_00789 5.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NGNKGMEN_00790 2.8e-16 WQ51_02665 S Protein of unknown function (DUF3042)
NGNKGMEN_00791 1.4e-45 yqhL P Rhodanese-like protein
NGNKGMEN_00792 4.7e-158 glk 2.7.1.2 G Glucokinase
NGNKGMEN_00793 2e-25 yqgQ S Bacterial protein of unknown function (DUF910)
NGNKGMEN_00794 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
NGNKGMEN_00795 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NGNKGMEN_00796 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NGNKGMEN_00797 1.8e-19 D nuclear chromosome segregation
NGNKGMEN_00798 4.1e-15 yciQ P membrane protein (DUF2207)
NGNKGMEN_00799 4.5e-252 L Transposase DDE domain group 1
NGNKGMEN_00800 1.2e-41 yciQ P membrane protein (DUF2207)
NGNKGMEN_00801 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NGNKGMEN_00802 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
NGNKGMEN_00803 2.9e-26 yneF S UPF0154 protein
NGNKGMEN_00804 2.2e-30 ynzC S UPF0291 protein
NGNKGMEN_00805 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NGNKGMEN_00806 9.3e-178 recN L May be involved in recombinational repair of damaged DNA
NGNKGMEN_00807 6.6e-49 argR K Regulates arginine biosynthesis genes
NGNKGMEN_00808 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NGNKGMEN_00809 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NGNKGMEN_00810 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NGNKGMEN_00811 8.9e-147 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NGNKGMEN_00812 1e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NGNKGMEN_00813 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NGNKGMEN_00814 3.7e-46 yqhY S Asp23 family, cell envelope-related function
NGNKGMEN_00815 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NGNKGMEN_00816 1.3e-41 dut S dUTPase
NGNKGMEN_00817 5.5e-117
NGNKGMEN_00818 7.3e-105
NGNKGMEN_00819 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NGNKGMEN_00820 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NGNKGMEN_00821 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NGNKGMEN_00822 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NGNKGMEN_00823 5.6e-127
NGNKGMEN_00824 5.1e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NGNKGMEN_00825 1.6e-42 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
NGNKGMEN_00826 2.3e-31 K Transcriptional regulator
NGNKGMEN_00827 2e-104 ybhR V ABC transporter
NGNKGMEN_00828 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
NGNKGMEN_00829 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NGNKGMEN_00830 8.8e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NGNKGMEN_00831 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NGNKGMEN_00832 2.2e-270 helD 3.6.4.12 L DNA helicase
NGNKGMEN_00834 1.3e-114 htpX O Belongs to the peptidase M48B family
NGNKGMEN_00835 8.7e-72 lemA S LemA family
NGNKGMEN_00836 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
NGNKGMEN_00837 3.2e-45 yjcF K protein acetylation
NGNKGMEN_00839 3.9e-254 yfiC V ABC transporter
NGNKGMEN_00840 9.9e-223 lmrA V ABC transporter, ATP-binding protein
NGNKGMEN_00841 9.2e-178 L PFAM Integrase catalytic region
NGNKGMEN_00843 6.3e-26
NGNKGMEN_00846 2.9e-112 potE2 E amino acid
NGNKGMEN_00847 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NGNKGMEN_00848 8.6e-62 divIVA D DivIVA domain protein
NGNKGMEN_00849 4.5e-82 ylmH S S4 domain protein
NGNKGMEN_00850 3e-19 yggT S YGGT family
NGNKGMEN_00851 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NGNKGMEN_00852 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NGNKGMEN_00853 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NGNKGMEN_00854 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NGNKGMEN_00855 1.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NGNKGMEN_00856 2e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NGNKGMEN_00857 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NGNKGMEN_00858 2.4e-279 ftsI 3.4.16.4 M Penicillin-binding Protein
NGNKGMEN_00859 2.5e-11 ftsL D cell division protein FtsL
NGNKGMEN_00860 8.8e-141 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NGNKGMEN_00861 5.2e-64 mraZ K Belongs to the MraZ family
NGNKGMEN_00862 3.4e-08 S Protein of unknown function (DUF3397)
NGNKGMEN_00863 2.7e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
NGNKGMEN_00864 6.3e-99 D Alpha beta
NGNKGMEN_00865 2.4e-108 aatB ET ABC transporter substrate-binding protein
NGNKGMEN_00866 1.1e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NGNKGMEN_00867 1.8e-92 glnP P ABC transporter permease
NGNKGMEN_00868 1.8e-126 minD D Belongs to the ParA family
NGNKGMEN_00869 1.4e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NGNKGMEN_00870 5.2e-55 mreD M rod shape-determining protein MreD
NGNKGMEN_00871 2.1e-88 mreC M Involved in formation and maintenance of cell shape
NGNKGMEN_00872 1.8e-155 mreB D cell shape determining protein MreB
NGNKGMEN_00873 4.5e-21 K Cold shock
NGNKGMEN_00874 3.1e-124 ubiE_2 Q Thiopurine S-methyltransferase (TPMT)
NGNKGMEN_00875 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NGNKGMEN_00876 4.6e-108 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NGNKGMEN_00877 5.1e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NGNKGMEN_00878 8e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NGNKGMEN_00879 4.2e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NGNKGMEN_00880 3e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NGNKGMEN_00881 1.7e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NGNKGMEN_00882 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NGNKGMEN_00883 1.1e-98 IQ reductase
NGNKGMEN_00884 5.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NGNKGMEN_00885 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NGNKGMEN_00886 1.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NGNKGMEN_00887 4.2e-61 marR K Transcriptional regulator, MarR family
NGNKGMEN_00888 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NGNKGMEN_00889 3e-36
NGNKGMEN_00891 7.4e-182 S Protein of unknown function DUF262
NGNKGMEN_00892 6.6e-193 pepV 3.5.1.18 E dipeptidase PepV
NGNKGMEN_00893 4.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NGNKGMEN_00894 2.5e-63 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NGNKGMEN_00895 6.4e-187 ytgP S Polysaccharide biosynthesis protein
NGNKGMEN_00896 2.4e-192 cycA E Amino acid permease
NGNKGMEN_00897 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NGNKGMEN_00898 2.1e-176 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NGNKGMEN_00908 2.1e-07
NGNKGMEN_00913 1.8e-12 yajC U Preprotein translocase
NGNKGMEN_00914 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NGNKGMEN_00915 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NGNKGMEN_00916 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NGNKGMEN_00917 5.6e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NGNKGMEN_00918 2.1e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NGNKGMEN_00919 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NGNKGMEN_00920 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
NGNKGMEN_00921 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NGNKGMEN_00922 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NGNKGMEN_00923 2.9e-64 ymfM S Helix-turn-helix domain
NGNKGMEN_00924 2.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
NGNKGMEN_00925 2.4e-149 ymfH S Peptidase M16
NGNKGMEN_00926 1.6e-108 ymfF S Peptidase M16 inactive domain protein
NGNKGMEN_00927 1e-283 ftsK D Belongs to the FtsK SpoIIIE SftA family
NGNKGMEN_00928 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NGNKGMEN_00929 2.1e-98 rrmA 2.1.1.187 H Methyltransferase
NGNKGMEN_00930 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NGNKGMEN_00931 8.1e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NGNKGMEN_00932 4.2e-21 cutC P Participates in the control of copper homeostasis
NGNKGMEN_00933 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NGNKGMEN_00934 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NGNKGMEN_00936 1.6e-73 dck 2.7.1.74 F deoxynucleoside kinase
NGNKGMEN_00938 1.5e-40 ntd 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
NGNKGMEN_00942 1.7e-54 L Phage integrase family
NGNKGMEN_00944 1.9e-49 tdk 2.7.1.21 F Thymidine kinase
NGNKGMEN_00949 1.1e-18 S protein disulfide oxidoreductase activity
NGNKGMEN_00951 3.2e-68 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NGNKGMEN_00952 1.9e-36 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NGNKGMEN_00959 1.1e-22
NGNKGMEN_00965 9.7e-22 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NGNKGMEN_00966 4.7e-11 S methyltransferase activity
NGNKGMEN_00967 2.8e-44 L DNA restriction-modification system
NGNKGMEN_00968 5.7e-70 2.1.1.72 L DNA methylase
NGNKGMEN_00975 7.3e-18 S Protein of unknown function (DUF1064)
NGNKGMEN_00976 4.7e-66 S DNA ligase (ATP) activity
NGNKGMEN_00978 1.5e-129 dnaE_2 2.7.7.7 L DNA polymerase
NGNKGMEN_00979 3.6e-29 S protein splicing
NGNKGMEN_00980 1.2e-89 dnaE_2 2.7.7.7 L DNA polymerase
NGNKGMEN_00981 4e-09
NGNKGMEN_00982 3.5e-43 S PD-(D/E)XK nuclease superfamily
NGNKGMEN_00983 2e-29 S DNA primase activity
NGNKGMEN_00985 2.6e-87 S Glycosyl hydrolases family 25
NGNKGMEN_00986 5.4e-83 S regulation of transcription, DNA-dependent
NGNKGMEN_00987 1.4e-10
NGNKGMEN_00991 4.4e-87 fliC N bacterial-type flagellum-dependent cell motility
NGNKGMEN_00992 4.4e-61
NGNKGMEN_00993 2e-59
NGNKGMEN_00994 4.8e-66 D Phage-related minor tail protein
NGNKGMEN_00995 4.9e-10 S Protein of unknown function (DUF805)
NGNKGMEN_00996 5.7e-71 xerH L Belongs to the 'phage' integrase family
NGNKGMEN_00997 2.4e-23 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NGNKGMEN_00998 1.9e-09 S RelB antitoxin
NGNKGMEN_01001 4e-14 S PFAM Holin toxin secretion phage lysis
NGNKGMEN_01005 1.9e-17 S peptidoglycan catabolic process
NGNKGMEN_01006 7.1e-33
NGNKGMEN_01011 6.8e-12 S by MetaGeneAnnotator
NGNKGMEN_01017 6.4e-43
NGNKGMEN_01018 4.7e-35
NGNKGMEN_01019 1.5e-170 gp17a S Terminase-like family
NGNKGMEN_01020 4.6e-10
NGNKGMEN_01022 1.7e-07 hup L Belongs to the bacterial histone-like protein family
NGNKGMEN_01024 1.6e-22
NGNKGMEN_01028 1.2e-40 S Replication initiator protein A (RepA) N-terminus
NGNKGMEN_01030 1e-82 soj D CobQ CobB MinD ParA nucleotide binding domain protein
NGNKGMEN_01035 3.4e-08 K Helix-turn-helix XRE-family like proteins
NGNKGMEN_01050 4.2e-14 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NGNKGMEN_01058 1.6e-77 K BRO family, N-terminal domain
NGNKGMEN_01060 1.1e-15 S Plasmid maintenance system killer
NGNKGMEN_01062 6.7e-62 L Belongs to the 'phage' integrase family
NGNKGMEN_01064 2.1e-13 2.7.1.24 H dephospho-CoA kinase activity
NGNKGMEN_01066 4e-10
NGNKGMEN_01067 3.1e-10 L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NGNKGMEN_01068 2.7e-56
NGNKGMEN_01069 7.7e-11
NGNKGMEN_01071 3.7e-93 3.6.4.12 L DnaB-like helicase C terminal domain
NGNKGMEN_01074 1.2e-114 recD 3.1.11.5 L Helix-hairpin-helix containing domain
NGNKGMEN_01077 5.7e-90 S nicotinamide riboside transmembrane transporter activity
NGNKGMEN_01088 5.1e-14 nrdH O Glutaredoxin-like protein
NGNKGMEN_01089 9.2e-132 L transposase, IS605 OrfB family
NGNKGMEN_01092 2.6e-140 L transposase, IS605 OrfB family
NGNKGMEN_01093 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NGNKGMEN_01095 2.9e-137 cggR K Putative sugar-binding domain
NGNKGMEN_01096 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NGNKGMEN_01097 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NGNKGMEN_01098 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NGNKGMEN_01099 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NGNKGMEN_01100 5e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NGNKGMEN_01101 5e-104 K response regulator
NGNKGMEN_01102 1.8e-169 T PhoQ Sensor
NGNKGMEN_01103 6.7e-146 lmrP E Major Facilitator Superfamily
NGNKGMEN_01104 9.2e-180 clcA P chloride
NGNKGMEN_01105 2.8e-19 secG U Preprotein translocase
NGNKGMEN_01106 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NGNKGMEN_01107 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NGNKGMEN_01108 3.1e-42 yxjI
NGNKGMEN_01109 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
NGNKGMEN_01110 6.8e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NGNKGMEN_01111 1.3e-142 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NGNKGMEN_01112 2.5e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NGNKGMEN_01113 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
NGNKGMEN_01114 1.2e-115 murB 1.3.1.98 M Cell wall formation
NGNKGMEN_01115 2.4e-71 S Protein of unknown function (DUF1361)
NGNKGMEN_01116 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NGNKGMEN_01117 5.3e-68 ybbR S YbbR-like protein
NGNKGMEN_01118 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NGNKGMEN_01119 1.1e-59 uspA T Universal stress protein family
NGNKGMEN_01120 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
NGNKGMEN_01121 1.1e-25
NGNKGMEN_01122 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NGNKGMEN_01123 8.8e-109 puuD S peptidase C26
NGNKGMEN_01124 3e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NGNKGMEN_01125 5.8e-147 lsa S ABC transporter
NGNKGMEN_01126 9.4e-149 mepA V MATE efflux family protein
NGNKGMEN_01127 1.4e-38 arbx M family 8
NGNKGMEN_01129 2.4e-31 M Glycosyltransferase like family 2
NGNKGMEN_01130 1.1e-69 nss M transferase activity, transferring glycosyl groups
NGNKGMEN_01131 3.9e-37 M Glycosyl transferase family 8
NGNKGMEN_01132 4.6e-55 nss M transferase activity, transferring glycosyl groups
NGNKGMEN_01134 5.1e-23 arbx M family 8
NGNKGMEN_01135 1.4e-07 M Glycosyltransferase like family 2
NGNKGMEN_01136 2e-66 nss M transferase activity, transferring glycosyl groups
NGNKGMEN_01137 7.3e-109 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NGNKGMEN_01138 9e-34 yxaB 2.4.1.166 GT2 M Glycosyltransferase like family 2
NGNKGMEN_01139 1.8e-151 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NGNKGMEN_01140 4.2e-08 L Helix-turn-helix domain
NGNKGMEN_01142 1.4e-10 L Helix-turn-helix domain
NGNKGMEN_01143 4e-16 L hmm pf00665
NGNKGMEN_01144 1.9e-48 L hmm pf00665
NGNKGMEN_01146 5.9e-24 3.2.1.18 GH33 M Rib/alpha-like repeat
NGNKGMEN_01147 3e-69 ybhL S Belongs to the BI1 family
NGNKGMEN_01148 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
NGNKGMEN_01149 3.8e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NGNKGMEN_01150 1.7e-238 sftA D Belongs to the FtsK SpoIIIE SftA family
NGNKGMEN_01151 2.5e-121 sip L Belongs to the 'phage' integrase family
NGNKGMEN_01152 3.5e-10 xre K sequence-specific DNA binding
NGNKGMEN_01153 1.7e-09 S Helix-turn-helix domain
NGNKGMEN_01154 1.5e-43 S Phage regulatory protein Rha (Phage_pRha)
NGNKGMEN_01162 1.6e-16 L DnaD domain protein
NGNKGMEN_01163 2.8e-09
NGNKGMEN_01166 6.9e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NGNKGMEN_01167 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NGNKGMEN_01168 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NGNKGMEN_01169 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
NGNKGMEN_01170 8.4e-72 ecsB U ABC transporter
NGNKGMEN_01171 9.8e-95 ecsA V ABC transporter, ATP-binding protein
NGNKGMEN_01172 7e-53 hit FG histidine triad
NGNKGMEN_01174 1.5e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NGNKGMEN_01175 7.3e-127 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
NGNKGMEN_01176 2e-21 yheA S Belongs to the UPF0342 family
NGNKGMEN_01177 1.1e-282 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NGNKGMEN_01180 6.7e-210 L Transposase IS116/IS110/IS902 family
NGNKGMEN_01182 9.2e-206 glnP P ABC transporter
NGNKGMEN_01183 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NGNKGMEN_01184 1.5e-31
NGNKGMEN_01185 2e-111 ampC V Beta-lactamase
NGNKGMEN_01186 3.5e-110 cobQ S glutamine amidotransferase
NGNKGMEN_01187 1e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NGNKGMEN_01188 6.8e-86 tdk 2.7.1.21 F thymidine kinase
NGNKGMEN_01189 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NGNKGMEN_01190 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NGNKGMEN_01191 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NGNKGMEN_01192 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NGNKGMEN_01193 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
NGNKGMEN_01194 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NGNKGMEN_01195 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NGNKGMEN_01196 4.1e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NGNKGMEN_01197 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NGNKGMEN_01198 5.1e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NGNKGMEN_01199 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NGNKGMEN_01200 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NGNKGMEN_01201 4.1e-15 ywzB S Protein of unknown function (DUF1146)
NGNKGMEN_01202 7.1e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NGNKGMEN_01203 3.4e-167 mbl D Cell shape determining protein MreB Mrl
NGNKGMEN_01204 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NGNKGMEN_01205 1.6e-13 S Protein of unknown function (DUF2969)
NGNKGMEN_01206 6.1e-187 rodA D Belongs to the SEDS family
NGNKGMEN_01207 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
NGNKGMEN_01208 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NGNKGMEN_01209 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NGNKGMEN_01210 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NGNKGMEN_01211 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NGNKGMEN_01212 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
NGNKGMEN_01213 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NGNKGMEN_01214 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NGNKGMEN_01215 7e-71 yacP S YacP-like NYN domain
NGNKGMEN_01216 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NGNKGMEN_01217 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NGNKGMEN_01218 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NGNKGMEN_01219 4.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NGNKGMEN_01220 8.2e-154 yacL S domain protein
NGNKGMEN_01221 1.6e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NGNKGMEN_01222 6.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NGNKGMEN_01223 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
NGNKGMEN_01224 6.4e-222 pepC 3.4.22.40 E Peptidase C1-like family
NGNKGMEN_01225 1.4e-33 S Enterocin A Immunity
NGNKGMEN_01226 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NGNKGMEN_01227 4.5e-129 mleP2 S Sodium Bile acid symporter family
NGNKGMEN_01228 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NGNKGMEN_01230 3.6e-44 ydcK S Belongs to the SprT family
NGNKGMEN_01231 2.8e-251 yhgF K Tex-like protein N-terminal domain protein
NGNKGMEN_01232 1.4e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NGNKGMEN_01233 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NGNKGMEN_01234 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NGNKGMEN_01235 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
NGNKGMEN_01236 4.6e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NGNKGMEN_01238 1.1e-07
NGNKGMEN_01239 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NGNKGMEN_01240 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NGNKGMEN_01241 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NGNKGMEN_01242 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
NGNKGMEN_01243 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NGNKGMEN_01244 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NGNKGMEN_01245 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NGNKGMEN_01246 1.6e-55 ctsR K Belongs to the CtsR family
NGNKGMEN_01248 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NGNKGMEN_01249 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NGNKGMEN_01250 1.8e-158 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NGNKGMEN_01251 7.2e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NGNKGMEN_01252 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NGNKGMEN_01262 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
NGNKGMEN_01263 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NGNKGMEN_01264 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NGNKGMEN_01265 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NGNKGMEN_01266 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NGNKGMEN_01267 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NGNKGMEN_01268 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NGNKGMEN_01269 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NGNKGMEN_01270 4.1e-08 KT PspC domain protein
NGNKGMEN_01271 1e-84 phoR 2.7.13.3 T Histidine kinase
NGNKGMEN_01272 3.5e-86 K response regulator
NGNKGMEN_01273 4.5e-67 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
NGNKGMEN_01274 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NGNKGMEN_01275 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NGNKGMEN_01276 3.1e-95 yeaN P Major Facilitator Superfamily
NGNKGMEN_01277 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NGNKGMEN_01278 3.7e-117 sip L Belongs to the 'phage' integrase family
NGNKGMEN_01279 7.6e-09 E IrrE N-terminal-like domain
NGNKGMEN_01280 3.9e-35 K Helix-turn-helix XRE-family like proteins
NGNKGMEN_01281 1.1e-07 K Helix-turn-helix XRE-family like proteins
NGNKGMEN_01282 1.4e-44 S Phage regulatory protein Rha (Phage_pRha)
NGNKGMEN_01283 3e-124 yvgN C Aldo keto reductase
NGNKGMEN_01284 2.6e-104 yraQ S Predicted permease
NGNKGMEN_01285 6.9e-62 yeeE S Sulphur transport
NGNKGMEN_01286 2e-16 yeeD O Belongs to the sulfur carrier protein TusA family
NGNKGMEN_01287 2.2e-116 ynjE 2.8.1.11 P Rhodanese Homology Domain
NGNKGMEN_01289 2.5e-235 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
NGNKGMEN_01290 7.1e-26 S Psort location Cytoplasmic, score
NGNKGMEN_01291 2e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
NGNKGMEN_01292 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
NGNKGMEN_01293 4.7e-73 prdD S An automated process has identified a potential problem with this gene model
NGNKGMEN_01294 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
NGNKGMEN_01295 7e-144 5.1.1.4 E Proline racemase
NGNKGMEN_01296 4.4e-94 XK27_00825 S Sulfite exporter TauE/SafE
NGNKGMEN_01297 5.3e-223 ybeC E amino acid
NGNKGMEN_01298 9e-49 yedF O Belongs to the sulfur carrier protein TusA family
NGNKGMEN_01299 4.5e-08 S Protein of unknown function (DUF3343)
NGNKGMEN_01300 3.1e-137 selB J Elongation factor SelB, winged helix
NGNKGMEN_01301 8.8e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
NGNKGMEN_01302 7e-110 selA 2.9.1.1 H Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
NGNKGMEN_01303 9e-29 yitW S Iron-sulfur cluster assembly protein
NGNKGMEN_01304 1.2e-175 rnfC C RnfC Barrel sandwich hybrid domain
NGNKGMEN_01305 7e-101 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
NGNKGMEN_01306 2.2e-149 yedE S Sulphur transport
NGNKGMEN_01307 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
NGNKGMEN_01308 9e-30 yqkB S Belongs to the HesB IscA family
NGNKGMEN_01309 1.8e-65 yxkH G Polysaccharide deacetylase
NGNKGMEN_01310 1.8e-07
NGNKGMEN_01311 1.7e-53 K LysR substrate binding domain
NGNKGMEN_01312 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
NGNKGMEN_01313 1.1e-199 nupG F Nucleoside
NGNKGMEN_01314 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NGNKGMEN_01315 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NGNKGMEN_01316 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NGNKGMEN_01317 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NGNKGMEN_01318 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NGNKGMEN_01319 9e-20 yaaA S S4 domain protein YaaA
NGNKGMEN_01320 8.4e-154 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NGNKGMEN_01321 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NGNKGMEN_01322 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NGNKGMEN_01323 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
NGNKGMEN_01324 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NGNKGMEN_01325 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NGNKGMEN_01326 5.6e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NGNKGMEN_01327 5.6e-117 S Glycosyl transferase family 2
NGNKGMEN_01328 5.7e-64 D peptidase
NGNKGMEN_01330 6.8e-73 gshR 1.8.1.7 C Glutathione reductase
NGNKGMEN_01331 4.9e-179 proV E ABC transporter, ATP-binding protein
NGNKGMEN_01332 5.3e-263 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NGNKGMEN_01335 3.5e-98 cadD P Cadmium resistance transporter
NGNKGMEN_01338 6e-34 L Helix-turn-helix domain
NGNKGMEN_01339 1.4e-67 spx4 1.20.4.1 P ArsC family
NGNKGMEN_01340 1.8e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NGNKGMEN_01341 2.9e-230 baeS 2.7.13.3 T Histidine kinase
NGNKGMEN_01342 5e-117 K response regulator
NGNKGMEN_01343 1.5e-33 3.2.1.23 S Domain of unknown function DUF302
NGNKGMEN_01344 4.8e-16 3.2.1.23 S Domain of unknown function DUF302
NGNKGMEN_01345 2.4e-40 S membrane protein (DUF2078)
NGNKGMEN_01346 0.0 3.6.3.4 P haloacid dehalogenase-like hydrolase
NGNKGMEN_01347 5.8e-79 copY K Penicillinase repressor
NGNKGMEN_01354 7.3e-77 infB UW LPXTG-motif cell wall anchor domain protein
NGNKGMEN_01355 1.4e-51
NGNKGMEN_01356 1.8e-82 L Transposase, IS116 IS110 IS902 family
NGNKGMEN_01357 2e-32 dprA LU DNA protecting protein DprA
NGNKGMEN_01358 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NGNKGMEN_01359 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NGNKGMEN_01360 3.6e-24 yozE S Belongs to the UPF0346 family
NGNKGMEN_01361 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NGNKGMEN_01362 6.5e-80 ypmR E GDSL-like Lipase/Acylhydrolase
NGNKGMEN_01364 3.5e-113 S Aldo keto reductase
NGNKGMEN_01365 4.2e-35 K helix_turn_helix, mercury resistance
NGNKGMEN_01366 1.6e-133 yvgN C Aldo keto reductase
NGNKGMEN_01367 4.7e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NGNKGMEN_01368 5.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NGNKGMEN_01369 2.2e-276 yfmR S ABC transporter, ATP-binding protein
NGNKGMEN_01370 1.1e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NGNKGMEN_01371 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NGNKGMEN_01372 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NGNKGMEN_01373 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
NGNKGMEN_01375 1.8e-56 yqeY S YqeY-like protein
NGNKGMEN_01376 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NGNKGMEN_01377 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NGNKGMEN_01380 5.8e-100 epsJ1 M Glycosyltransferase like family 2
NGNKGMEN_01381 2.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
NGNKGMEN_01382 6.2e-92 M transferase activity, transferring glycosyl groups
NGNKGMEN_01383 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NGNKGMEN_01384 2.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NGNKGMEN_01385 1.5e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NGNKGMEN_01386 5.1e-56 dnaD L DnaD domain protein
NGNKGMEN_01387 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NGNKGMEN_01388 3.1e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NGNKGMEN_01389 1.4e-36 ypmB S Protein conserved in bacteria
NGNKGMEN_01390 1.5e-225 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NGNKGMEN_01391 9.5e-95 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NGNKGMEN_01392 1.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NGNKGMEN_01393 6.7e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NGNKGMEN_01394 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NGNKGMEN_01395 8.4e-105 holA 2.7.7.7 L DNA polymerase III delta subunit
NGNKGMEN_01396 2.1e-156 comEC S Competence protein ComEC
NGNKGMEN_01397 2e-69 comEB 3.5.4.12 F ComE operon protein 2
NGNKGMEN_01398 3.1e-50 comEA L Competence protein ComEA
NGNKGMEN_01399 3.4e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
NGNKGMEN_01400 4e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NGNKGMEN_01401 2.2e-20
NGNKGMEN_01403 2.3e-122 K LysR substrate binding domain
NGNKGMEN_01404 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NGNKGMEN_01405 1.3e-108 S Acyltransferase family
NGNKGMEN_01406 6e-161 purD 6.3.4.13 F Belongs to the GARS family
NGNKGMEN_01407 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NGNKGMEN_01408 1.2e-74 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NGNKGMEN_01409 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NGNKGMEN_01410 5.5e-227 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NGNKGMEN_01411 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NGNKGMEN_01412 1.2e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NGNKGMEN_01413 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NGNKGMEN_01414 2.9e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NGNKGMEN_01415 1.8e-131 ylbL T Belongs to the peptidase S16 family
NGNKGMEN_01416 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NGNKGMEN_01417 1e-72 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NGNKGMEN_01418 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NGNKGMEN_01419 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NGNKGMEN_01420 3e-101 ftsW D Belongs to the SEDS family
NGNKGMEN_01421 2.5e-148 manN G system, mannose fructose sorbose family IID component
NGNKGMEN_01422 7e-115 manY G PTS system
NGNKGMEN_01423 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NGNKGMEN_01424 0.0 typA T GTP-binding protein TypA
NGNKGMEN_01425 6.3e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NGNKGMEN_01426 1.2e-24 yktA S Belongs to the UPF0223 family
NGNKGMEN_01427 2.6e-30 1.1.1.27 C L-malate dehydrogenase activity
NGNKGMEN_01428 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NGNKGMEN_01429 9.5e-25
NGNKGMEN_01430 5e-23 ykzG S Belongs to the UPF0356 family
NGNKGMEN_01431 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NGNKGMEN_01432 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NGNKGMEN_01433 7.8e-198 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NGNKGMEN_01434 7.8e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NGNKGMEN_01435 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NGNKGMEN_01436 6.1e-19 S Tetratricopeptide repeat
NGNKGMEN_01437 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NGNKGMEN_01438 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NGNKGMEN_01439 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NGNKGMEN_01440 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
NGNKGMEN_01441 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NGNKGMEN_01442 8.2e-199 yfnA E amino acid
NGNKGMEN_01443 3.3e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
NGNKGMEN_01444 1.9e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NGNKGMEN_01445 1.5e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NGNKGMEN_01446 3.8e-27 ylqC S Belongs to the UPF0109 family
NGNKGMEN_01447 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NGNKGMEN_01448 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NGNKGMEN_01449 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NGNKGMEN_01450 7.2e-146 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NGNKGMEN_01451 1.3e-208 smc D Required for chromosome condensation and partitioning
NGNKGMEN_01452 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NGNKGMEN_01453 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NGNKGMEN_01454 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NGNKGMEN_01455 8.8e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NGNKGMEN_01456 1.3e-238 yloV S DAK2 domain fusion protein YloV
NGNKGMEN_01457 4.5e-53 asp S Asp23 family, cell envelope-related function
NGNKGMEN_01458 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NGNKGMEN_01459 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
NGNKGMEN_01460 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NGNKGMEN_01461 1.7e-190 KLT serine threonine protein kinase
NGNKGMEN_01462 3.3e-90 stp 3.1.3.16 T phosphatase
NGNKGMEN_01463 1.3e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NGNKGMEN_01464 1.3e-139 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NGNKGMEN_01465 1.3e-286 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NGNKGMEN_01466 6.4e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NGNKGMEN_01467 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NGNKGMEN_01468 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NGNKGMEN_01469 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
NGNKGMEN_01470 5.3e-15
NGNKGMEN_01471 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
NGNKGMEN_01472 2.7e-309 S TIGR02687 family
NGNKGMEN_01473 0.0 V restriction
NGNKGMEN_01474 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
NGNKGMEN_01475 1.5e-68 S Domain of unknown function (DUF1788)
NGNKGMEN_01476 1.7e-79 S Putative inner membrane protein (DUF1819)
NGNKGMEN_01477 2.5e-26 K Cro/C1-type HTH DNA-binding domain
NGNKGMEN_01479 3.6e-58 hsdM 2.1.1.72 V HsdM N-terminal domain
NGNKGMEN_01480 4.9e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
NGNKGMEN_01481 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NGNKGMEN_01482 3.2e-86 S (CBS) domain
NGNKGMEN_01483 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NGNKGMEN_01484 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NGNKGMEN_01485 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NGNKGMEN_01486 1.2e-139 yabM S Polysaccharide biosynthesis protein
NGNKGMEN_01487 3.6e-31 yabO J S4 domain protein
NGNKGMEN_01488 2.3e-18 divIC D Septum formation initiator
NGNKGMEN_01489 1.1e-40 yabR J RNA binding
NGNKGMEN_01490 7.2e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NGNKGMEN_01491 1.9e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NGNKGMEN_01492 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NGNKGMEN_01493 2e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NGNKGMEN_01494 3.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NGNKGMEN_01495 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NGNKGMEN_01496 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NGNKGMEN_01497 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NGNKGMEN_01498 5e-87 S Alpha beta hydrolase
NGNKGMEN_01499 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NGNKGMEN_01500 3.6e-140 V MatE
NGNKGMEN_01501 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
NGNKGMEN_01502 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NGNKGMEN_01503 4.3e-97 V ABC transporter
NGNKGMEN_01504 9.6e-132 bacI V MacB-like periplasmic core domain
NGNKGMEN_01505 9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NGNKGMEN_01506 1.7e-26
NGNKGMEN_01507 2.1e-180 yhdP S Transporter associated domain
NGNKGMEN_01508 3.9e-78 ptp2 3.1.3.48 T Tyrosine phosphatase family
NGNKGMEN_01509 0.0 L Helicase C-terminal domain protein
NGNKGMEN_01510 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NGNKGMEN_01511 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NGNKGMEN_01512 1.5e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NGNKGMEN_01513 7.8e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NGNKGMEN_01514 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NGNKGMEN_01515 2.8e-79 dnaB L replication initiation and membrane attachment
NGNKGMEN_01516 9.7e-108 dnaI L Primosomal protein DnaI
NGNKGMEN_01517 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NGNKGMEN_01518 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NGNKGMEN_01519 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NGNKGMEN_01520 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NGNKGMEN_01521 2.5e-71 yqeG S HAD phosphatase, family IIIA
NGNKGMEN_01522 3e-180 yqeH S Ribosome biogenesis GTPase YqeH
NGNKGMEN_01523 1e-29 yhbY J RNA-binding protein
NGNKGMEN_01524 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NGNKGMEN_01525 4.7e-71 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NGNKGMEN_01526 5.1e-49 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NGNKGMEN_01527 5.5e-82 H Nodulation protein S (NodS)
NGNKGMEN_01528 1.3e-122 ylbM S Belongs to the UPF0348 family
NGNKGMEN_01529 3.5e-57 yceD S Uncharacterized ACR, COG1399
NGNKGMEN_01530 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NGNKGMEN_01531 5.1e-195 XK27_08315 M Sulfatase
NGNKGMEN_01533 1.1e-167 mdtG EGP Major facilitator Superfamily
NGNKGMEN_01534 1.5e-252 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NGNKGMEN_01535 6.3e-83 treR K UTRA
NGNKGMEN_01536 2.5e-259 treB G phosphotransferase system
NGNKGMEN_01537 7.1e-64 3.1.3.73 G phosphoglycerate mutase
NGNKGMEN_01538 1.8e-82 pncA Q isochorismatase
NGNKGMEN_01539 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NGNKGMEN_01540 2.9e-102 ydhQ K UbiC transcription regulator-associated domain protein
NGNKGMEN_01541 2.5e-170 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NGNKGMEN_01542 4e-33 K Transcriptional regulator, HxlR family
NGNKGMEN_01543 0.0 asnB 6.3.5.4 E Asparagine synthase
NGNKGMEN_01544 1.6e-60 yiiE S Protein of unknown function (DUF1211)
NGNKGMEN_01545 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NGNKGMEN_01546 5.7e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NGNKGMEN_01547 3.6e-17 yneR
NGNKGMEN_01548 8.7e-231 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NGNKGMEN_01549 5.5e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
NGNKGMEN_01550 9.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NGNKGMEN_01551 1.9e-151 mdtG EGP Major facilitator Superfamily
NGNKGMEN_01552 5.9e-15 K regulatory protein TetR
NGNKGMEN_01553 4.8e-109 glcU U sugar transport
NGNKGMEN_01554 1.6e-167 yjjP S Putative threonine/serine exporter
NGNKGMEN_01555 1.5e-68 2.3.1.178 J Acetyltransferase (GNAT) domain
NGNKGMEN_01556 8.2e-07 fhaB M Rib/alpha-like repeat
NGNKGMEN_01557 1e-148 3.2.1.18 GH33 M Rib/alpha-like repeat
NGNKGMEN_01558 1.9e-95 ypuA S Protein of unknown function (DUF1002)
NGNKGMEN_01559 1.1e-59 dedA 3.1.3.1 S SNARE associated Golgi protein
NGNKGMEN_01560 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NGNKGMEN_01561 9.3e-37 yncA 2.3.1.79 S Maltose acetyltransferase
NGNKGMEN_01562 3.4e-205 yflS P Sodium:sulfate symporter transmembrane region
NGNKGMEN_01563 1.4e-198 frdC 1.3.5.4 C FAD binding domain
NGNKGMEN_01564 1.9e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NGNKGMEN_01565 5.7e-14 ybaN S Protein of unknown function (DUF454)
NGNKGMEN_01566 9.7e-178 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NGNKGMEN_01567 7.8e-49 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
NGNKGMEN_01568 3.5e-22 S Cytochrome B5
NGNKGMEN_01569 4e-19 sigH K DNA-templated transcription, initiation
NGNKGMEN_01570 3.4e-69 recX 2.4.1.337 GT4 S Regulatory protein RecX
NGNKGMEN_01571 6.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NGNKGMEN_01572 2.6e-97 ygaC J Belongs to the UPF0374 family
NGNKGMEN_01573 2.4e-92 yueF S AI-2E family transporter
NGNKGMEN_01574 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NGNKGMEN_01575 1.8e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NGNKGMEN_01576 4e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NGNKGMEN_01577 0.0 lacL 3.2.1.23 G -beta-galactosidase
NGNKGMEN_01579 5.2e-70 rny D Peptidase family M23
NGNKGMEN_01580 2.1e-76 M transferase activity, transferring glycosyl groups
NGNKGMEN_01581 2e-57 cps3F
NGNKGMEN_01582 1.5e-160 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
NGNKGMEN_01583 2.9e-62 S Glycosyltransferase like family 2
NGNKGMEN_01584 4.3e-195 glf 5.4.99.9 M UDP-galactopyranose mutase
NGNKGMEN_01586 2.6e-91 rfbP M Bacterial sugar transferase
NGNKGMEN_01587 4.8e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NGNKGMEN_01588 1.6e-111 ywqE 3.1.3.48 GM PHP domain protein
NGNKGMEN_01596 5.1e-08
NGNKGMEN_01602 1.4e-06
NGNKGMEN_01603 6.7e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NGNKGMEN_01604 1.7e-54 rplI J Binds to the 23S rRNA
NGNKGMEN_01605 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NGNKGMEN_01606 1.2e-63 C FMN binding
NGNKGMEN_01607 2.8e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NGNKGMEN_01609 3.9e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NGNKGMEN_01610 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
NGNKGMEN_01611 7.9e-12 S CAAX protease self-immunity
NGNKGMEN_01612 1.8e-80 S Belongs to the UPF0246 family
NGNKGMEN_01613 1.8e-99 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NGNKGMEN_01614 1.8e-95 EG EamA-like transporter family
NGNKGMEN_01615 5.9e-80 yjjH S Calcineurin-like phosphoesterase
NGNKGMEN_01616 1.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NGNKGMEN_01617 1e-30 6.3.3.2 I Protein conserved in bacteria
NGNKGMEN_01618 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
NGNKGMEN_01619 1.8e-116 degV S EDD domain protein, DegV family
NGNKGMEN_01620 3.1e-40 K Transcriptional regulator
NGNKGMEN_01621 5.9e-204 FbpA K Fibronectin-binding protein
NGNKGMEN_01622 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NGNKGMEN_01623 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NGNKGMEN_01624 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NGNKGMEN_01625 2.2e-39 ypaA S Protein of unknown function (DUF1304)
NGNKGMEN_01627 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NGNKGMEN_01628 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NGNKGMEN_01629 0.0 dnaE 2.7.7.7 L DNA polymerase
NGNKGMEN_01630 4.3e-15 S Protein of unknown function (DUF2929)
NGNKGMEN_01631 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NGNKGMEN_01632 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NGNKGMEN_01633 3.7e-41 XK27_04120 S Putative amino acid metabolism
NGNKGMEN_01634 1.3e-159 iscS 2.8.1.7 E Aminotransferase class V
NGNKGMEN_01635 5.5e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NGNKGMEN_01637 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NGNKGMEN_01638 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NGNKGMEN_01639 8.5e-161 nhaC C Na H antiporter NhaC
NGNKGMEN_01641 7e-127 corA P CorA-like Mg2+ transporter protein
NGNKGMEN_01642 8.7e-299 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NGNKGMEN_01643 3.4e-204 hisS 6.1.1.21 J histidyl-tRNA synthetase
NGNKGMEN_01644 3.6e-150 S Tetratricopeptide repeat protein
NGNKGMEN_01645 3.8e-136 EG EamA-like transporter family
NGNKGMEN_01646 1.2e-72 alkD L DNA alkylation repair enzyme
NGNKGMEN_01647 8.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NGNKGMEN_01648 6.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NGNKGMEN_01649 7.8e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
NGNKGMEN_01650 1.1e-149 EGP Sugar (and other) transporter
NGNKGMEN_01652 1.8e-38
NGNKGMEN_01653 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NGNKGMEN_01654 1.5e-22 S Family of unknown function (DUF5322)
NGNKGMEN_01655 3.1e-36 rnhA 3.1.26.4 L Ribonuclease HI
NGNKGMEN_01656 6.1e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NGNKGMEN_01657 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NGNKGMEN_01659 9.2e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NGNKGMEN_01660 1.2e-171 patA 2.6.1.1 E Aminotransferase
NGNKGMEN_01661 1.1e-114 glcR K DeoR C terminal sensor domain
NGNKGMEN_01662 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
NGNKGMEN_01663 4.7e-134 K Transcriptional regulator
NGNKGMEN_01664 2e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NGNKGMEN_01665 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NGNKGMEN_01666 3.8e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NGNKGMEN_01667 7.4e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NGNKGMEN_01668 3.5e-204 pyrP F Permease
NGNKGMEN_01669 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NGNKGMEN_01670 1.4e-127 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NGNKGMEN_01671 3.4e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NGNKGMEN_01672 5.1e-57 3.1.3.18 J HAD-hyrolase-like
NGNKGMEN_01673 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NGNKGMEN_01674 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NGNKGMEN_01675 4.8e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NGNKGMEN_01676 2.2e-117 prmA J Ribosomal protein L11 methyltransferase
NGNKGMEN_01677 2.9e-42 XK27_03960 S Protein of unknown function (DUF3013)
NGNKGMEN_01678 3.9e-144 iunH2 3.2.2.1 F nucleoside hydrolase
NGNKGMEN_01679 6.4e-12
NGNKGMEN_01680 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NGNKGMEN_01681 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
NGNKGMEN_01682 1.8e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NGNKGMEN_01683 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NGNKGMEN_01684 1.3e-172 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NGNKGMEN_01685 6.9e-43 yodB K Transcriptional regulator, HxlR family
NGNKGMEN_01686 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NGNKGMEN_01687 1e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NGNKGMEN_01691 2.8e-279 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NGNKGMEN_01692 2.4e-44 S Repeat protein
NGNKGMEN_01693 8.9e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NGNKGMEN_01694 9.5e-48 M Exporter of polyketide antibiotics
NGNKGMEN_01695 2e-93 M Exporter of polyketide antibiotics
NGNKGMEN_01696 2.2e-204 G PTS system Galactitol-specific IIC component
NGNKGMEN_01697 3.4e-118 sip L Belongs to the 'phage' integrase family
NGNKGMEN_01698 1.2e-10 K Helix-turn-helix XRE-family like proteins
NGNKGMEN_01701 6.8e-39 K COG3617 Prophage antirepressor
NGNKGMEN_01709 2.8e-44 L Bifunctional DNA primase/polymerase, N-terminal
NGNKGMEN_01710 5.4e-135 S D5 N terminal like
NGNKGMEN_01711 7.3e-94 C Luciferase-like monooxygenase
NGNKGMEN_01712 1.3e-67 1.5.1.38 S NADPH-dependent FMN reductase
NGNKGMEN_01713 2.2e-116 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NGNKGMEN_01714 5.2e-76 L haloacid dehalogenase-like hydrolase
NGNKGMEN_01715 3.1e-61 EG EamA-like transporter family
NGNKGMEN_01716 1.2e-117 K AI-2E family transporter
NGNKGMEN_01717 2.4e-172 malY 4.4.1.8 E Aminotransferase, class I
NGNKGMEN_01718 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NGNKGMEN_01720 4e-16
NGNKGMEN_01721 6.1e-103 V domain protein
NGNKGMEN_01722 7.7e-35 K Bacterial regulatory proteins, tetR family
NGNKGMEN_01723 9.5e-246 yhcA V ABC transporter, ATP-binding protein
NGNKGMEN_01724 2.6e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NGNKGMEN_01725 6.6e-146 G Transporter, major facilitator family protein
NGNKGMEN_01726 5.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
NGNKGMEN_01727 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
NGNKGMEN_01728 2.5e-113 K response regulator
NGNKGMEN_01729 3.4e-89 patB 4.4.1.8 E Aminotransferase, class I
NGNKGMEN_01730 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NGNKGMEN_01732 2.1e-21 XK27_09445 S Domain of unknown function (DUF1827)
NGNKGMEN_01733 1.1e-104 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NGNKGMEN_01734 3e-311 rafA 3.2.1.22 G alpha-galactosidase
NGNKGMEN_01735 5.9e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NGNKGMEN_01736 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NGNKGMEN_01737 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NGNKGMEN_01738 5.9e-111 galR K Transcriptional regulator
NGNKGMEN_01739 8.9e-289 lacS G Transporter
NGNKGMEN_01740 3.2e-56 S peptidoglycan catabolic process
NGNKGMEN_01741 7.3e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NGNKGMEN_01742 2e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NGNKGMEN_01743 2e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NGNKGMEN_01744 1.9e-177 thrC 4.2.3.1 E Threonine synthase
NGNKGMEN_01745 1.7e-79 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NGNKGMEN_01746 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
NGNKGMEN_01747 3.3e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NGNKGMEN_01748 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NGNKGMEN_01749 3.6e-220 cydD CO ABC transporter transmembrane region
NGNKGMEN_01750 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NGNKGMEN_01751 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NGNKGMEN_01752 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
NGNKGMEN_01753 1.8e-127 tnp L DDE domain
NGNKGMEN_01754 0.0 tetP J elongation factor G
NGNKGMEN_01755 4e-48 L Resolvase, N terminal domain
NGNKGMEN_01758 5.4e-18
NGNKGMEN_01759 8.8e-53 L Protein involved in initiation of plasmid replication
NGNKGMEN_01760 1.8e-208 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NGNKGMEN_01761 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NGNKGMEN_01764 7e-152 V Pfam:Methyltransf_26
NGNKGMEN_01765 7.5e-225 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NGNKGMEN_01766 1e-111 argE 3.5.1.18 E Peptidase dimerisation domain
NGNKGMEN_01767 1.2e-100 IQ Enoyl-(Acyl carrier protein) reductase
NGNKGMEN_01768 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
NGNKGMEN_01769 4.3e-54 queT S QueT transporter
NGNKGMEN_01771 3.3e-65 degV S Uncharacterised protein, DegV family COG1307
NGNKGMEN_01772 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NGNKGMEN_01773 9.4e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NGNKGMEN_01774 1.9e-34 trxA O Belongs to the thioredoxin family
NGNKGMEN_01775 4.2e-86 S Sucrose-6F-phosphate phosphohydrolase
NGNKGMEN_01776 1.2e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NGNKGMEN_01777 8.3e-49 S Threonine/Serine exporter, ThrE
NGNKGMEN_01778 4.3e-82 thrE S Putative threonine/serine exporter
NGNKGMEN_01779 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
NGNKGMEN_01780 5.4e-13
NGNKGMEN_01781 1.5e-144 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NGNKGMEN_01782 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NGNKGMEN_01783 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NGNKGMEN_01784 9e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NGNKGMEN_01785 6.4e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
NGNKGMEN_01786 1.2e-180 pbuG S permease
NGNKGMEN_01788 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
NGNKGMEN_01789 6e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NGNKGMEN_01790 1.3e-118 gla U Major intrinsic protein
NGNKGMEN_01791 1.5e-45 ykuL S CBS domain
NGNKGMEN_01792 3e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NGNKGMEN_01793 2.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NGNKGMEN_01794 2.6e-86 ykuT M mechanosensitive ion channel
NGNKGMEN_01795 1.4e-154 oppF P Belongs to the ABC transporter superfamily
NGNKGMEN_01796 1.3e-180 oppD P Belongs to the ABC transporter superfamily
NGNKGMEN_01797 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NGNKGMEN_01798 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NGNKGMEN_01799 1.1e-202 oppA E ABC transporter, substratebinding protein
NGNKGMEN_01800 3.5e-218 yifK E Amino acid permease
NGNKGMEN_01801 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NGNKGMEN_01802 3.9e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
NGNKGMEN_01803 6.5e-66 pgm3 G phosphoglycerate mutase family
NGNKGMEN_01804 1.3e-252 ctpA 3.6.3.54 P P-type ATPase
NGNKGMEN_01805 5.7e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NGNKGMEN_01806 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NGNKGMEN_01807 2.1e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NGNKGMEN_01808 5.1e-137 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NGNKGMEN_01809 4.3e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NGNKGMEN_01810 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NGNKGMEN_01811 1.6e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
NGNKGMEN_01812 1e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
NGNKGMEN_01813 9e-42 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
NGNKGMEN_01814 1.3e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NGNKGMEN_01815 4.1e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NGNKGMEN_01816 5.1e-71 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NGNKGMEN_01817 5.4e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
NGNKGMEN_01818 1.4e-45 yphJ 4.1.1.44 S decarboxylase
NGNKGMEN_01819 1.1e-55 yphH S Cupin domain
NGNKGMEN_01820 2.4e-46 C Flavodoxin
NGNKGMEN_01821 3.6e-56 S CAAX protease self-immunity
NGNKGMEN_01822 1.2e-102 pgm3 G phosphoglycerate mutase
NGNKGMEN_01823 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NGNKGMEN_01824 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NGNKGMEN_01825 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NGNKGMEN_01826 7.4e-67 M ErfK YbiS YcfS YnhG
NGNKGMEN_01827 1e-107 XK27_08845 S ABC transporter, ATP-binding protein
NGNKGMEN_01828 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NGNKGMEN_01829 7.8e-132 ABC-SBP S ABC transporter
NGNKGMEN_01830 1.1e-158 potD P ABC transporter
NGNKGMEN_01831 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
NGNKGMEN_01832 9.5e-120 potB P ABC transporter permease
NGNKGMEN_01833 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NGNKGMEN_01834 9.6e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NGNKGMEN_01835 1.6e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
NGNKGMEN_01836 1.5e-235 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NGNKGMEN_01837 3.9e-13 S Enterocin A Immunity
NGNKGMEN_01838 2.2e-16 pspC KT PspC domain
NGNKGMEN_01839 3.1e-16 S Putative adhesin
NGNKGMEN_01840 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
NGNKGMEN_01841 8.1e-38 K transcriptional regulator PadR family
NGNKGMEN_01842 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NGNKGMEN_01843 4.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
NGNKGMEN_01844 2.4e-164 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NGNKGMEN_01845 1.1e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NGNKGMEN_01846 3.5e-70 mltD CBM50 M NlpC P60 family protein
NGNKGMEN_01847 1.8e-52 manO S Domain of unknown function (DUF956)
NGNKGMEN_01848 2.1e-147 manN G system, mannose fructose sorbose family IID component
NGNKGMEN_01849 6.4e-116 manY G PTS system sorbose-specific iic component
NGNKGMEN_01850 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NGNKGMEN_01851 4.1e-80 rbsB G sugar-binding domain protein
NGNKGMEN_01852 5.1e-99 baeS T Histidine kinase
NGNKGMEN_01853 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
NGNKGMEN_01854 5.3e-120 G Bacterial extracellular solute-binding protein
NGNKGMEN_01855 9.1e-71 S Protein of unknown function (DUF554)
NGNKGMEN_01856 1e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NGNKGMEN_01857 1.9e-32 merR K MerR HTH family regulatory protein
NGNKGMEN_01858 2.1e-197 lmrB EGP Major facilitator Superfamily
NGNKGMEN_01859 7e-34 S Domain of unknown function (DUF4811)
NGNKGMEN_01860 4.3e-41 S CAAX protease self-immunity
NGNKGMEN_01861 1.3e-60 yceE S haloacid dehalogenase-like hydrolase
NGNKGMEN_01862 7.6e-74 glcR K DeoR C terminal sensor domain
NGNKGMEN_01863 4.8e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NGNKGMEN_01864 1.7e-183 lmrB EGP Major facilitator Superfamily
NGNKGMEN_01865 2.1e-54 bioY S BioY family
NGNKGMEN_01866 1.8e-94 S Predicted membrane protein (DUF2207)
NGNKGMEN_01867 1.4e-19
NGNKGMEN_01868 1.3e-36 M Glycosyltransferase group 2 family protein
NGNKGMEN_01869 4.8e-53 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NGNKGMEN_01870 6.3e-58 ktrA P TrkA-N domain
NGNKGMEN_01871 2.1e-114 ntpJ P Potassium uptake protein
NGNKGMEN_01872 5.3e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NGNKGMEN_01873 3.1e-27 cspC K Cold shock protein
NGNKGMEN_01874 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
NGNKGMEN_01875 4.5e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NGNKGMEN_01876 1.6e-22
NGNKGMEN_01877 1.2e-58 3.6.1.27 I phosphatase
NGNKGMEN_01878 1.8e-22
NGNKGMEN_01879 3.6e-66 I alpha/beta hydrolase fold
NGNKGMEN_01880 1.3e-38 azlD S branched-chain amino acid
NGNKGMEN_01881 1.9e-104 azlC E AzlC protein
NGNKGMEN_01882 2e-17
NGNKGMEN_01883 8.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
NGNKGMEN_01884 3.4e-30 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
NGNKGMEN_01885 1.2e-78 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
NGNKGMEN_01886 0.0 S Bacterial membrane protein YfhO
NGNKGMEN_01887 5.1e-53 gtcA S Teichoic acid glycosylation protein
NGNKGMEN_01888 5.1e-54 fld C Flavodoxin
NGNKGMEN_01889 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
NGNKGMEN_01890 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NGNKGMEN_01891 1.1e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NGNKGMEN_01892 4.2e-58 radC L DNA repair protein
NGNKGMEN_01893 2.7e-202 intIA L similarity to EGAD 7942
NGNKGMEN_01894 0.0 L similarity to EGAD 8390
NGNKGMEN_01895 1.9e-57 S similarity to EGAD 6135
NGNKGMEN_01896 3.2e-144 ant 2.7.7.47 S Domain of unknown function (DUF4111)
NGNKGMEN_01897 5.2e-83 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
NGNKGMEN_01898 5.6e-156 L Transposase
NGNKGMEN_01899 1.3e-75 K sequence-specific DNA binding
NGNKGMEN_01900 8.9e-38 1.6.5.2 S NADPH-dependent FMN reductase
NGNKGMEN_01901 6.3e-274 lsa S ABC transporter
NGNKGMEN_01902 8.6e-42 S MazG-like family
NGNKGMEN_01904 5e-55 repB L Initiator Replication protein
NGNKGMEN_01905 3.7e-72 K Putative ATP-dependent DNA helicase recG C-terminal
NGNKGMEN_01906 2.4e-79 sip L Belongs to the 'phage' integrase family
NGNKGMEN_01907 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NGNKGMEN_01908 7.2e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
NGNKGMEN_01909 1.5e-27 yazA L GIY-YIG catalytic domain protein
NGNKGMEN_01910 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
NGNKGMEN_01911 4e-89 plsC 2.3.1.51 I Acyltransferase
NGNKGMEN_01912 2.1e-19 M domain protein
NGNKGMEN_01913 3e-35 agrA KT Response regulator of the LytR AlgR family
NGNKGMEN_01914 5.1e-43 2.7.13.3 T protein histidine kinase activity
NGNKGMEN_01915 0.0 pepN 3.4.11.2 E aminopeptidase
NGNKGMEN_01916 2.8e-28
NGNKGMEN_01917 3.5e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NGNKGMEN_01918 8.4e-119 ytbE S reductase
NGNKGMEN_01919 3e-41 ytcD K HxlR-like helix-turn-helix
NGNKGMEN_01920 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
NGNKGMEN_01921 4.5e-67 ybbL S ABC transporter
NGNKGMEN_01922 6.2e-163 oxlT P Major Facilitator Superfamily
NGNKGMEN_01923 4.7e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NGNKGMEN_01924 2.4e-47 S Short repeat of unknown function (DUF308)
NGNKGMEN_01926 1.7e-92 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
NGNKGMEN_01928 7.3e-79 L Replication protein
NGNKGMEN_01930 9.5e-79 L Replication protein
NGNKGMEN_01931 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
NGNKGMEN_01932 2.6e-91 T Calcineurin-like phosphoesterase superfamily domain
NGNKGMEN_01933 4.2e-49 lytE M LysM domain protein
NGNKGMEN_01934 5e-19 glpE P Rhodanese Homology Domain
NGNKGMEN_01935 3.1e-27 xlyB 3.5.1.28 CBM50 M LysM domain
NGNKGMEN_01936 9.1e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
NGNKGMEN_01937 1.1e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NGNKGMEN_01938 1e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
NGNKGMEN_01939 1.7e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NGNKGMEN_01940 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
NGNKGMEN_01941 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NGNKGMEN_01942 3.7e-12
NGNKGMEN_01944 3.1e-71
NGNKGMEN_01945 1.5e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NGNKGMEN_01946 2.5e-177 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NGNKGMEN_01947 7.9e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
NGNKGMEN_01948 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NGNKGMEN_01949 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NGNKGMEN_01950 3.5e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NGNKGMEN_01951 1.2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NGNKGMEN_01952 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NGNKGMEN_01953 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NGNKGMEN_01954 3.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NGNKGMEN_01955 4.1e-51 yeaL S Protein of unknown function (DUF441)
NGNKGMEN_01956 4.8e-125 cvfB S S1 domain
NGNKGMEN_01957 3.6e-112 xerD D recombinase XerD
NGNKGMEN_01958 2.1e-292 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NGNKGMEN_01959 2.3e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NGNKGMEN_01960 3.7e-188 nhaC C Na H antiporter NhaC
NGNKGMEN_01961 7.8e-65 ypsA S Belongs to the UPF0398 family
NGNKGMEN_01962 2.9e-198 ade 3.5.4.2 F Adenine deaminase C-terminal domain
NGNKGMEN_01964 4e-57 2.3.1.178 M GNAT acetyltransferase
NGNKGMEN_01965 5.1e-08 2.3.1.178 M phosphinothricin N-acetyltransferase activity
NGNKGMEN_01966 1.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
NGNKGMEN_01967 5.7e-57 3.6.1.27 I Acid phosphatase homologues
NGNKGMEN_01968 3e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
NGNKGMEN_01970 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NGNKGMEN_01971 8.8e-202 hsdM 2.1.1.72 V type I restriction-modification system
NGNKGMEN_01972 1.9e-66 hsdS_1 3.1.21.3 V Type I Restriction
NGNKGMEN_01973 6.1e-131 L Belongs to the 'phage' integrase family
NGNKGMEN_01974 9.9e-87 3.1.21.3 V Type I restriction modification DNA specificity domain
NGNKGMEN_01975 9.7e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NGNKGMEN_01976 7.6e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
NGNKGMEN_01977 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NGNKGMEN_01978 9.6e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NGNKGMEN_01979 1.2e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NGNKGMEN_01980 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NGNKGMEN_01981 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
NGNKGMEN_01982 1.3e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
NGNKGMEN_01983 1.9e-126 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NGNKGMEN_01984 7.7e-12 M Lysin motif
NGNKGMEN_01985 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NGNKGMEN_01986 6.8e-84 lytH 3.5.1.28 M Ami_3
NGNKGMEN_01987 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
NGNKGMEN_01988 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NGNKGMEN_01989 2.8e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NGNKGMEN_01990 4.6e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NGNKGMEN_01991 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
NGNKGMEN_01992 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
NGNKGMEN_01993 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NGNKGMEN_01994 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
NGNKGMEN_01995 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NGNKGMEN_01996 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NGNKGMEN_01997 5.3e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
NGNKGMEN_01998 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
NGNKGMEN_01999 7.7e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NGNKGMEN_02000 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NGNKGMEN_02002 6.2e-23 K Acetyltransferase (GNAT) domain
NGNKGMEN_02003 6.2e-112 natA S Domain of unknown function (DUF4162)
NGNKGMEN_02004 2.5e-84 natB CP ABC-type Na efflux pump, permease component
NGNKGMEN_02006 9.4e-109 L Initiator Replication protein
NGNKGMEN_02007 1.6e-36 S Replication initiator protein A (RepA) N-terminus
NGNKGMEN_02008 2.3e-169 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NGNKGMEN_02009 2e-47 pts33BCA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G Pts system
NGNKGMEN_02010 1.3e-231 pepF E oligoendopeptidase F
NGNKGMEN_02011 1.2e-67 coiA 3.6.4.12 S Competence protein
NGNKGMEN_02012 9.2e-48 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NGNKGMEN_02013 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NGNKGMEN_02015 9.2e-16 psiE S Phosphate-starvation-inducible E
NGNKGMEN_02016 5.4e-208 mmuP E amino acid
NGNKGMEN_02017 6.9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NGNKGMEN_02018 5.3e-40 K LytTr DNA-binding domain
NGNKGMEN_02019 1.3e-17 S Protein of unknown function (DUF3021)
NGNKGMEN_02020 4.2e-151 yfeX P Peroxidase
NGNKGMEN_02021 2.2e-12 tetR K Transcriptional regulator C-terminal region
NGNKGMEN_02024 1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
NGNKGMEN_02025 3.5e-216 scrB 3.2.1.26 GH32 G invertase
NGNKGMEN_02026 1.7e-147 scrR K helix_turn _helix lactose operon repressor
NGNKGMEN_02027 2.8e-28 L HTH-like domain
NGNKGMEN_02028 4.5e-30 L Helix-turn-helix domain
NGNKGMEN_02030 6.2e-210 glnP P ABC transporter
NGNKGMEN_02031 9.3e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NGNKGMEN_02032 8.1e-64 L COG3385 FOG Transposase and inactivated derivatives
NGNKGMEN_02033 1.7e-24 L Transposase DDE domain
NGNKGMEN_02034 8.9e-192 XK27_11280 S Psort location CytoplasmicMembrane, score
NGNKGMEN_02036 1.1e-106 L Belongs to the 'phage' integrase family
NGNKGMEN_02037 0.0 clpE O Belongs to the ClpA ClpB family
NGNKGMEN_02038 1.5e-15
NGNKGMEN_02039 9.7e-37 ptsH G phosphocarrier protein HPR
NGNKGMEN_02040 6.9e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NGNKGMEN_02041 5.5e-24 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NGNKGMEN_02042 9.2e-36 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
NGNKGMEN_02043 2.4e-181 gatC G PTS system sugar-specific permease component
NGNKGMEN_02044 7.3e-120 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NGNKGMEN_02045 1.1e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NGNKGMEN_02046 5.9e-222 infB NU MucBP domain
NGNKGMEN_02047 7.5e-20
NGNKGMEN_02048 3e-59 L IS66 Orf2 like protein
NGNKGMEN_02049 3.6e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NGNKGMEN_02050 5.5e-243 lysP E amino acid
NGNKGMEN_02051 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
NGNKGMEN_02052 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NGNKGMEN_02053 1.2e-13 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NGNKGMEN_02054 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
NGNKGMEN_02055 7.6e-83 lysR5 K LysR substrate binding domain
NGNKGMEN_02056 1.7e-119 yxaA S membrane transporter protein
NGNKGMEN_02057 2.6e-32 ywjH S Protein of unknown function (DUF1634)
NGNKGMEN_02058 7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NGNKGMEN_02059 1.7e-225 pipD E Dipeptidase
NGNKGMEN_02060 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
NGNKGMEN_02061 5.7e-165 EGP Major facilitator Superfamily
NGNKGMEN_02062 4.7e-81 S L,D-transpeptidase catalytic domain
NGNKGMEN_02063 1.9e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NGNKGMEN_02064 1.3e-143 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NGNKGMEN_02065 7.2e-27 ydiI Q Thioesterase superfamily
NGNKGMEN_02066 5.6e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
NGNKGMEN_02067 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NGNKGMEN_02068 6.4e-114 degV S EDD domain protein, DegV family
NGNKGMEN_02069 3.4e-226 cadA P P-type ATPase
NGNKGMEN_02070 1.8e-254 E Amino acid permease
NGNKGMEN_02071 2.1e-83 S Membrane
NGNKGMEN_02072 2e-49 cps3F
NGNKGMEN_02073 3.3e-283 fruA 2.7.1.202 GT Phosphotransferase System
NGNKGMEN_02074 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NGNKGMEN_02075 9e-88 fruR K DeoR C terminal sensor domain
NGNKGMEN_02076 6.7e-219 XK27_08635 S UPF0210 protein
NGNKGMEN_02077 4.1e-27 gcvR T Belongs to the UPF0237 family
NGNKGMEN_02078 2.3e-38
NGNKGMEN_02079 1.1e-76 E GDSL-like Lipase/Acylhydrolase family
NGNKGMEN_02080 9.2e-56 S Protein of unknown function (DUF975)
NGNKGMEN_02081 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
NGNKGMEN_02082 4e-230 lpdA 1.8.1.4 C Dehydrogenase
NGNKGMEN_02083 2.9e-179 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NGNKGMEN_02084 2.8e-166 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NGNKGMEN_02085 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NGNKGMEN_02088 2.3e-34 S Protein of unknown function (DUF4256)
NGNKGMEN_02089 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
NGNKGMEN_02090 2.4e-31 metI U ABC transporter permease
NGNKGMEN_02091 2.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NGNKGMEN_02093 3.3e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NGNKGMEN_02094 6.2e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NGNKGMEN_02095 2.3e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NGNKGMEN_02096 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
NGNKGMEN_02097 3e-84 drgA C nitroreductase
NGNKGMEN_02098 8.8e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NGNKGMEN_02099 9.6e-68 metI P ABC transporter permease
NGNKGMEN_02100 1.5e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NGNKGMEN_02101 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
NGNKGMEN_02102 1e-143 2.1.1.14 E methionine synthase, vitamin-B12 independent
NGNKGMEN_02103 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NGNKGMEN_02104 1.7e-60 K DeoR C terminal sensor domain
NGNKGMEN_02106 1.7e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NGNKGMEN_02108 3.1e-111 K response regulator
NGNKGMEN_02109 1.3e-167 arlS 2.7.13.3 T Histidine kinase
NGNKGMEN_02110 1.2e-131 S D5 N terminal like
NGNKGMEN_02111 1.1e-45 L DNA replication protein
NGNKGMEN_02114 1.3e-73 draG O ADP-ribosylglycohydrolase
NGNKGMEN_02115 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NGNKGMEN_02116 3.7e-90 yunF F Protein of unknown function DUF72
NGNKGMEN_02117 1.7e-156 nrnB S DHHA1 domain
NGNKGMEN_02118 4.8e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NGNKGMEN_02119 3.8e-59
NGNKGMEN_02120 1.6e-10 S Transposase C of IS166 homeodomain
NGNKGMEN_02121 7e-141 L Transposase IS66 family
NGNKGMEN_02122 6.2e-105 L Transposase IS66 family
NGNKGMEN_02123 1.1e-201 L Transposase
NGNKGMEN_02124 4.6e-247 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
NGNKGMEN_02126 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
NGNKGMEN_02127 6.6e-63 licT K transcriptional antiterminator
NGNKGMEN_02128 1.4e-28 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NGNKGMEN_02129 4e-149 whiA K May be required for sporulation
NGNKGMEN_02130 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NGNKGMEN_02131 7.5e-126 rapZ S Displays ATPase and GTPase activities
NGNKGMEN_02132 4.7e-12 mltD CBM50 M Lysin motif
NGNKGMEN_02133 3.8e-93 yihY S Belongs to the UPF0761 family
NGNKGMEN_02134 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NGNKGMEN_02135 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NGNKGMEN_02136 1.7e-162 iscS2 2.8.1.7 E Aminotransferase class V
NGNKGMEN_02137 7.1e-173 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NGNKGMEN_02138 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
NGNKGMEN_02139 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NGNKGMEN_02140 7.7e-24 yueI S Protein of unknown function (DUF1694)
NGNKGMEN_02141 3.4e-188 rarA L recombination factor protein RarA
NGNKGMEN_02143 3.2e-73 usp6 T universal stress protein
NGNKGMEN_02144 3.1e-53 tag 3.2.2.20 L glycosylase
NGNKGMEN_02145 1.3e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NGNKGMEN_02146 3.8e-124 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NGNKGMEN_02148 2e-75 yviA S Protein of unknown function (DUF421)
NGNKGMEN_02149 2e-26 S Protein of unknown function (DUF3290)
NGNKGMEN_02150 1.5e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
NGNKGMEN_02151 2.3e-295 S membrane
NGNKGMEN_02152 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NGNKGMEN_02153 1.4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
NGNKGMEN_02154 2.9e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
NGNKGMEN_02155 1.5e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NGNKGMEN_02157 4.1e-16
NGNKGMEN_02158 2.5e-200 oatA I Acyltransferase
NGNKGMEN_02159 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NGNKGMEN_02160 1.6e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NGNKGMEN_02161 2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NGNKGMEN_02164 6.7e-42 S Phosphoesterase
NGNKGMEN_02165 3.6e-71 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NGNKGMEN_02166 1.1e-60 yslB S Protein of unknown function (DUF2507)
NGNKGMEN_02167 9.9e-41 trxA O Belongs to the thioredoxin family
NGNKGMEN_02168 6.5e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NGNKGMEN_02169 2.9e-14 cvpA S Colicin V production protein
NGNKGMEN_02170 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NGNKGMEN_02171 2.1e-32 yrzB S Belongs to the UPF0473 family
NGNKGMEN_02172 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NGNKGMEN_02173 2.1e-36 yrzL S Belongs to the UPF0297 family
NGNKGMEN_02174 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NGNKGMEN_02175 6.7e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NGNKGMEN_02176 9.4e-122 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NGNKGMEN_02177 7.5e-13
NGNKGMEN_02178 3.9e-146 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NGNKGMEN_02179 1.6e-65 yrjD S LUD domain
NGNKGMEN_02180 2.1e-245 lutB C 4Fe-4S dicluster domain
NGNKGMEN_02181 9e-117 lutA C Cysteine-rich domain
NGNKGMEN_02182 2e-208 yfnA E Amino Acid
NGNKGMEN_02184 4.3e-61 uspA T universal stress protein
NGNKGMEN_02186 1.6e-197 dtpT U amino acid peptide transporter
NGNKGMEN_02187 6.6e-232 L Transposase
NGNKGMEN_02188 2.1e-153 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NGNKGMEN_02190 1.6e-143 L Probable transposase
NGNKGMEN_02191 1.3e-64 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
NGNKGMEN_02192 1.8e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NGNKGMEN_02193 1.2e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
NGNKGMEN_02194 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
NGNKGMEN_02195 4.5e-43 gutM K Glucitol operon activator protein (GutM)
NGNKGMEN_02196 9.9e-104 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
NGNKGMEN_02197 5.2e-110 IQ NAD dependent epimerase/dehydratase family
NGNKGMEN_02198 4.7e-163 ytbD EGP Major facilitator Superfamily
NGNKGMEN_02199 3.9e-98 fabK 1.3.1.9 S Nitronate monooxygenase
NGNKGMEN_02200 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NGNKGMEN_02202 4.1e-265 fbp 3.1.3.11 G phosphatase activity
NGNKGMEN_02203 2.4e-70 xerD L Phage integrase, N-terminal SAM-like domain
NGNKGMEN_02204 2.2e-10 blpT
NGNKGMEN_02205 4.7e-120 sip L Belongs to the 'phage' integrase family
NGNKGMEN_02206 2.5e-24 K Cro/C1-type HTH DNA-binding domain
NGNKGMEN_02207 7.3e-13 K Cro/C1-type HTH DNA-binding domain
NGNKGMEN_02208 4.5e-07 S sequence-specific DNA binding
NGNKGMEN_02209 1.4e-44 S Phage regulatory protein Rha (Phage_pRha)
NGNKGMEN_02210 2.3e-19 K Transcriptional regulator
NGNKGMEN_02216 2.1e-16
NGNKGMEN_02217 9.6e-45 L Bifunctional DNA primase/polymerase, N-terminal
NGNKGMEN_02218 1.9e-75 S DNA primase
NGNKGMEN_02220 1.4e-14
NGNKGMEN_02222 2.3e-14
NGNKGMEN_02224 1.4e-28 S Phage gp6-like head-tail connector protein
NGNKGMEN_02225 2e-97
NGNKGMEN_02226 1.3e-06 S Domain of unknown function (DUF4355)
NGNKGMEN_02229 1.1e-26 S Phage Mu protein F like protein
NGNKGMEN_02230 4.5e-16 S Phage Mu protein F like protein
NGNKGMEN_02231 2.7e-187 mtnE 2.6.1.83 E Aminotransferase
NGNKGMEN_02232 1e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NGNKGMEN_02233 3.4e-67 S Protein of unknown function (DUF1440)
NGNKGMEN_02234 5.9e-41 S Iron-sulfur cluster assembly protein
NGNKGMEN_02235 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NGNKGMEN_02236 2.1e-72 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NGNKGMEN_02237 1.1e-206 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NGNKGMEN_02238 6.6e-154 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NGNKGMEN_02239 4.7e-65 G Xylose isomerase domain protein TIM barrel
NGNKGMEN_02240 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
NGNKGMEN_02241 1.2e-88 nanK GK ROK family
NGNKGMEN_02242 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NGNKGMEN_02243 3.3e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NGNKGMEN_02244 4.3e-75 K Helix-turn-helix domain, rpiR family
NGNKGMEN_02245 5.7e-56 yphA GM NAD dependent epimerase/dehydratase family
NGNKGMEN_02246 6.9e-217 yjeM E Amino Acid
NGNKGMEN_02248 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NGNKGMEN_02249 1.1e-233 tetP J elongation factor G
NGNKGMEN_02250 1.4e-276 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NGNKGMEN_02251 3.5e-88 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)