ORF_ID e_value Gene_name EC_number CAZy COGs Description
KKOJADAG_00001 5.2e-81 usp6 T universal stress protein
KKOJADAG_00003 3.6e-238 rarA L recombination factor protein RarA
KKOJADAG_00004 2.4e-83 yueI S Protein of unknown function (DUF1694)
KKOJADAG_00005 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KKOJADAG_00007 2.1e-289 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KKOJADAG_00008 4.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
KKOJADAG_00009 1.1e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KKOJADAG_00010 2.5e-124 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KKOJADAG_00011 2.1e-178 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KKOJADAG_00012 0.0 3.6.3.8 P P-type ATPase
KKOJADAG_00013 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KKOJADAG_00014 7.4e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KKOJADAG_00015 6.4e-125 S Haloacid dehalogenase-like hydrolase
KKOJADAG_00016 6.1e-111 radC L DNA repair protein
KKOJADAG_00017 2.7e-164 mreB D cell shape determining protein MreB
KKOJADAG_00018 6.1e-141 mreC M Involved in formation and maintenance of cell shape
KKOJADAG_00019 1.6e-94 mreD
KKOJADAG_00020 3.6e-13 S Protein of unknown function (DUF4044)
KKOJADAG_00021 2.7e-52 S Protein of unknown function (DUF3397)
KKOJADAG_00022 4.1e-77 mraZ K Belongs to the MraZ family
KKOJADAG_00023 1.7e-179 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KKOJADAG_00024 4.8e-55 ftsL D Cell division protein FtsL
KKOJADAG_00025 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KKOJADAG_00026 3.5e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KKOJADAG_00027 3.6e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KKOJADAG_00028 1.5e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KKOJADAG_00029 2e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KKOJADAG_00030 6e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KKOJADAG_00031 1.1e-243 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KKOJADAG_00032 1.3e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KKOJADAG_00033 7.8e-27 yggT S YGGT family
KKOJADAG_00034 2.4e-147 ylmH S S4 domain protein
KKOJADAG_00035 3.2e-120 gpsB D DivIVA domain protein
KKOJADAG_00036 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KKOJADAG_00037 2.3e-33 cspA K 'Cold-shock' DNA-binding domain
KKOJADAG_00038 1.7e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KKOJADAG_00039 4.9e-34
KKOJADAG_00040 1.1e-127 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KKOJADAG_00041 3.5e-216 iscS 2.8.1.7 E Aminotransferase class V
KKOJADAG_00042 9.6e-58 XK27_04120 S Putative amino acid metabolism
KKOJADAG_00043 8.7e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KKOJADAG_00044 3.1e-124 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KKOJADAG_00045 1e-116 S Repeat protein
KKOJADAG_00046 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KKOJADAG_00047 2.6e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KKOJADAG_00048 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KKOJADAG_00049 2.3e-34 ykzG S Belongs to the UPF0356 family
KKOJADAG_00050 5.2e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KKOJADAG_00051 0.0 typA T GTP-binding protein TypA
KKOJADAG_00052 7.7e-211 ftsW D Belongs to the SEDS family
KKOJADAG_00053 7.4e-50 ylbG S UPF0298 protein
KKOJADAG_00054 2.1e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KKOJADAG_00055 9.6e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KKOJADAG_00056 1.5e-183 ylbL T Belongs to the peptidase S16 family
KKOJADAG_00057 1.1e-84 comEA L Competence protein ComEA
KKOJADAG_00058 0.0 comEC S Competence protein ComEC
KKOJADAG_00059 5.2e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
KKOJADAG_00060 4.4e-34 rpsT J Binds directly to 16S ribosomal RNA
KKOJADAG_00061 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KKOJADAG_00062 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KKOJADAG_00063 7.2e-158
KKOJADAG_00064 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KKOJADAG_00065 4e-203 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KKOJADAG_00066 2.1e-230 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KKOJADAG_00067 1.7e-102 engB D Necessary for normal cell division and for the maintenance of normal septation
KKOJADAG_00068 2.2e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KKOJADAG_00069 5.1e-82
KKOJADAG_00071 1.7e-114 frnE Q DSBA-like thioredoxin domain
KKOJADAG_00072 6e-78 S Domain of unknown function (DUF4767)
KKOJADAG_00073 9.2e-218
KKOJADAG_00074 2.5e-121 frnE Q DSBA-like thioredoxin domain
KKOJADAG_00075 9.6e-163
KKOJADAG_00076 6.4e-79 K DNA-templated transcription, initiation
KKOJADAG_00077 4.6e-156 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KKOJADAG_00078 3.7e-138 epsB M biosynthesis protein
KKOJADAG_00079 8.7e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KKOJADAG_00080 2.6e-138 ywqE 3.1.3.48 GM PHP domain protein
KKOJADAG_00081 5.1e-82 rfbP 2.7.8.6 M Bacterial sugar transferase
KKOJADAG_00082 5.8e-138 cps1D M Domain of unknown function (DUF4422)
KKOJADAG_00083 1.3e-124 waaB GT4 M Glycosyl transferases group 1
KKOJADAG_00084 4e-40 S O-antigen ligase like membrane protein
KKOJADAG_00085 5.5e-53 M Glycosyltransferase like family 2
KKOJADAG_00086 8.2e-50 G Protein of unknown function (DUF563)
KKOJADAG_00087 5.5e-65 S Glycosyltransferase like family 2
KKOJADAG_00088 8.6e-102 M transferase activity, transferring glycosyl groups
KKOJADAG_00089 6.2e-45 H Core-2/I-Branching enzyme
KKOJADAG_00090 3.3e-211 glf 5.4.99.9 M UDP-galactopyranose mutase
KKOJADAG_00091 1.9e-251 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
KKOJADAG_00093 7.5e-183 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KKOJADAG_00094 1.3e-124 manY G PTS system
KKOJADAG_00095 3.3e-172 manN G system, mannose fructose sorbose family IID component
KKOJADAG_00096 1.8e-65 manO S Domain of unknown function (DUF956)
KKOJADAG_00097 1.5e-253 yifK E Amino acid permease
KKOJADAG_00098 3.5e-231 yifK E Amino acid permease
KKOJADAG_00099 3.1e-138 puuD S peptidase C26
KKOJADAG_00100 1.6e-234 steT_1 E amino acid
KKOJADAG_00101 9e-192 asnA 6.3.1.1 F aspartate--ammonia ligase
KKOJADAG_00102 3.9e-162 EG EamA-like transporter family
KKOJADAG_00103 6e-255 yfnA E Amino Acid
KKOJADAG_00104 7.8e-131 cobQ S glutamine amidotransferase
KKOJADAG_00105 4.4e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KKOJADAG_00106 4.4e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
KKOJADAG_00107 6.6e-139 scrR K Transcriptional regulator, LacI family
KKOJADAG_00108 2.9e-300 scrB 3.2.1.26 GH32 G invertase
KKOJADAG_00109 0.0 scrA 2.7.1.199, 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
KKOJADAG_00110 6.5e-36
KKOJADAG_00111 2.5e-86 ymdB S Macro domain protein
KKOJADAG_00112 6.2e-296 V ABC transporter transmembrane region
KKOJADAG_00113 1.7e-125 puuD S peptidase C26
KKOJADAG_00114 2.6e-138 mdtG EGP Major facilitator Superfamily
KKOJADAG_00115 1.3e-75 mdtG EGP Major Facilitator Superfamily
KKOJADAG_00116 4e-156
KKOJADAG_00117 4.3e-71 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
KKOJADAG_00118 8e-156 2.7.7.12 C Domain of unknown function (DUF4931)
KKOJADAG_00119 6.3e-154 ybbH_2 K Helix-turn-helix domain, rpiR family
KKOJADAG_00120 5.3e-144 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
KKOJADAG_00121 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
KKOJADAG_00122 1.6e-252 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKOJADAG_00123 3.9e-162 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KKOJADAG_00124 1.3e-128
KKOJADAG_00125 8.5e-52
KKOJADAG_00126 5.4e-141 S Belongs to the UPF0246 family
KKOJADAG_00127 1e-139 aroD S Alpha/beta hydrolase family
KKOJADAG_00128 3.6e-114 G Phosphoglycerate mutase family
KKOJADAG_00129 4.6e-111 G phosphoglycerate mutase
KKOJADAG_00130 2.4e-92 ygfC K Bacterial regulatory proteins, tetR family
KKOJADAG_00131 1.2e-183 hrtB V ABC transporter permease
KKOJADAG_00132 3.1e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KKOJADAG_00133 5.1e-156 K CAT RNA binding domain
KKOJADAG_00134 0.0 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKOJADAG_00135 4.1e-294 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKOJADAG_00136 1.7e-273 pipD E Dipeptidase
KKOJADAG_00137 1.8e-37
KKOJADAG_00138 2e-109 K WHG domain
KKOJADAG_00139 2.2e-96 nqr 1.5.1.36 S reductase
KKOJADAG_00140 3.7e-99 azr 1.5.1.36 S NADPH-dependent FMN reductase
KKOJADAG_00141 1.1e-200 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KKOJADAG_00142 5.7e-149 3.1.3.48 T Tyrosine phosphatase family
KKOJADAG_00143 4e-178 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KKOJADAG_00144 6.4e-96 cvpA S Colicin V production protein
KKOJADAG_00145 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KKOJADAG_00146 1.1e-142 noc K Belongs to the ParB family
KKOJADAG_00147 9.7e-138 soj D Sporulation initiation inhibitor
KKOJADAG_00148 2.2e-154 spo0J K Belongs to the ParB family
KKOJADAG_00149 1.9e-42 yyzM S Bacterial protein of unknown function (DUF951)
KKOJADAG_00150 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KKOJADAG_00151 3.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
KKOJADAG_00152 3.2e-298 V ABC transporter, ATP-binding protein
KKOJADAG_00153 0.0 V ABC transporter
KKOJADAG_00154 7.4e-121 K response regulator
KKOJADAG_00155 4.8e-205 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
KKOJADAG_00156 2.2e-306 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KKOJADAG_00157 1.3e-142 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KKOJADAG_00158 4.4e-166 natA S ABC transporter, ATP-binding protein
KKOJADAG_00159 1.7e-221 natB CP ABC-2 family transporter protein
KKOJADAG_00160 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KKOJADAG_00161 1.4e-136 fruR K DeoR C terminal sensor domain
KKOJADAG_00162 1.2e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KKOJADAG_00163 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
KKOJADAG_00164 5.4e-67 S YSIRK type signal peptide
KKOJADAG_00165 0.0 2.7.7.7 M domain protein
KKOJADAG_00166 4.7e-140 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
KKOJADAG_00167 1.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
KKOJADAG_00168 1.2e-158 psaA P Belongs to the bacterial solute-binding protein 9 family
KKOJADAG_00169 1.6e-117 fhuC P ABC transporter
KKOJADAG_00170 8.7e-134 znuB U ABC 3 transport family
KKOJADAG_00171 1.2e-256 lctP C L-lactate permease
KKOJADAG_00172 0.0 pepF E oligoendopeptidase F
KKOJADAG_00173 9e-209 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KKOJADAG_00174 6.2e-39
KKOJADAG_00175 4.3e-62
KKOJADAG_00176 3.6e-285 S ABC transporter
KKOJADAG_00177 2.4e-136 thrE S Putative threonine/serine exporter
KKOJADAG_00178 2.8e-79 S Threonine/Serine exporter, ThrE
KKOJADAG_00179 4e-40
KKOJADAG_00180 4.7e-60 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KKOJADAG_00181 1.3e-79
KKOJADAG_00182 6.4e-176 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KKOJADAG_00183 7.7e-82 nrdI F Belongs to the NrdI family
KKOJADAG_00184 1.4e-110
KKOJADAG_00185 4.6e-272 S O-antigen ligase like membrane protein
KKOJADAG_00186 5.3e-44
KKOJADAG_00187 1.4e-98 gmk2 2.7.4.8 F Guanylate kinase
KKOJADAG_00188 6.9e-119 M NlpC P60 family protein
KKOJADAG_00189 5.3e-231 S Putative peptidoglycan binding domain
KKOJADAG_00190 3.4e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KKOJADAG_00192 1.3e-74
KKOJADAG_00193 7e-136 V ABC transporter
KKOJADAG_00194 4.2e-122 V Transport permease protein
KKOJADAG_00195 7.7e-121 V ABC-2 type transporter
KKOJADAG_00196 6.2e-279 E amino acid
KKOJADAG_00197 6.3e-134 cysA V ABC transporter, ATP-binding protein
KKOJADAG_00198 0.0 V FtsX-like permease family
KKOJADAG_00199 8.8e-124 pgm3 G Phosphoglycerate mutase family
KKOJADAG_00200 2.8e-26
KKOJADAG_00201 1.3e-52
KKOJADAG_00202 1.9e-149 xth 3.1.11.2 L exodeoxyribonuclease III
KKOJADAG_00203 0.0 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
KKOJADAG_00204 3.1e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KKOJADAG_00205 9.6e-144 rpiR1 K Helix-turn-helix domain, rpiR family
KKOJADAG_00206 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
KKOJADAG_00208 2.1e-117 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KKOJADAG_00209 0.0 helD 3.6.4.12 L DNA helicase
KKOJADAG_00210 3.3e-119 yvpB S Peptidase_C39 like family
KKOJADAG_00211 4.9e-102 E GDSL-like Lipase/Acylhydrolase
KKOJADAG_00212 1.9e-163 coaA 2.7.1.33 F Pantothenic acid kinase
KKOJADAG_00213 7.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KKOJADAG_00214 0.0 fhaB M Rib/alpha-like repeat
KKOJADAG_00215 5.5e-71 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKOJADAG_00216 4.7e-155 EG EamA-like transporter family
KKOJADAG_00217 0.0 oppA E ABC transporter substrate-binding protein
KKOJADAG_00218 2.6e-161 2.7.1.191 G PTS system sorbose subfamily IIB component
KKOJADAG_00219 1.4e-139 G PTS system sorbose-specific iic component
KKOJADAG_00220 1.5e-144 G PTS system mannose/fructose/sorbose family IID component
KKOJADAG_00221 3.4e-62
KKOJADAG_00222 1.4e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KKOJADAG_00223 1.9e-203 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
KKOJADAG_00224 9.6e-237 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KKOJADAG_00225 1.3e-75
KKOJADAG_00226 1.3e-93
KKOJADAG_00227 9.8e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
KKOJADAG_00228 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KKOJADAG_00229 3.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KKOJADAG_00230 2.5e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KKOJADAG_00231 6.8e-98 dnaQ 2.7.7.7 L DNA polymerase III
KKOJADAG_00232 7.6e-166 murB 1.3.1.98 M Cell wall formation
KKOJADAG_00233 3.8e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KKOJADAG_00234 1e-129 potB P ABC transporter permease
KKOJADAG_00235 8.5e-137 potC P ABC transporter permease
KKOJADAG_00236 5.9e-210 potD P ABC transporter
KKOJADAG_00237 2.9e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KKOJADAG_00238 2.9e-171 ybbR S YbbR-like protein
KKOJADAG_00239 4.5e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KKOJADAG_00240 2.4e-147 S Sucrose-6F-phosphate phosphohydrolase
KKOJADAG_00241 7.7e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKOJADAG_00242 4.5e-61 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KKOJADAG_00243 7e-199 S Putative adhesin
KKOJADAG_00244 1.6e-115
KKOJADAG_00245 8e-148 yisY 1.11.1.10 S Alpha/beta hydrolase family
KKOJADAG_00246 7e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
KKOJADAG_00247 1.8e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KKOJADAG_00248 4.7e-96 S VanZ like family
KKOJADAG_00249 1.5e-132 yebC K Transcriptional regulatory protein
KKOJADAG_00250 1.5e-180 comGA NU Type II IV secretion system protein
KKOJADAG_00251 9.9e-175 comGB NU type II secretion system
KKOJADAG_00252 1.2e-40 comGC U Required for transformation and DNA binding
KKOJADAG_00253 4.1e-58
KKOJADAG_00254 7.5e-11
KKOJADAG_00255 4e-84 comGF U Putative Competence protein ComGF
KKOJADAG_00256 4.3e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
KKOJADAG_00257 1e-226 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KKOJADAG_00259 2.1e-149 L Belongs to the 'phage' integrase family
KKOJADAG_00261 1.3e-27 S Bacterial PH domain
KKOJADAG_00262 1.8e-83 S Pfam:Peptidase_M78
KKOJADAG_00263 5.1e-57 S protein disulfide oxidoreductase activity
KKOJADAG_00264 2.5e-09 K Helix-turn-helix XRE-family like proteins
KKOJADAG_00265 1.9e-58 S Domain of unknown function (DUF771)
KKOJADAG_00267 2.9e-15
KKOJADAG_00268 7.5e-39
KKOJADAG_00270 8e-44 S ERF superfamily
KKOJADAG_00271 5.1e-67 L Helix-turn-helix domain
KKOJADAG_00272 2.4e-18 K Transcriptional regulator
KKOJADAG_00275 2.4e-133 S DNA binding
KKOJADAG_00276 1.4e-25
KKOJADAG_00282 6.8e-62 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
KKOJADAG_00283 7.6e-42
KKOJADAG_00285 3.1e-17
KKOJADAG_00286 8.6e-23
KKOJADAG_00287 9.8e-19
KKOJADAG_00288 1.9e-86
KKOJADAG_00292 4e-29
KKOJADAG_00293 5.5e-64 xtmA L Terminase small subunit
KKOJADAG_00294 2.4e-242 S Phage terminase, large subunit
KKOJADAG_00295 1.9e-235 S Phage portal protein, SPP1 Gp6-like
KKOJADAG_00296 1.5e-42 S Phage Mu protein F like protein
KKOJADAG_00297 4.6e-61 patB 4.4.1.8 E Aminotransferase, class I
KKOJADAG_00298 5e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
KKOJADAG_00299 6e-67 S SdpI/YhfL protein family
KKOJADAG_00300 2.2e-128 K Transcriptional regulatory protein, C terminal
KKOJADAG_00301 2.6e-269 T PhoQ Sensor
KKOJADAG_00302 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KKOJADAG_00303 2.2e-105 vanZ V VanZ like family
KKOJADAG_00304 1.9e-261 pgi 5.3.1.9 G Belongs to the GPI family
KKOJADAG_00305 2.2e-233 EGP Major facilitator Superfamily
KKOJADAG_00306 3.2e-69
KKOJADAG_00309 1.1e-194 ampC V Beta-lactamase
KKOJADAG_00310 5.5e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
KKOJADAG_00311 5.5e-112 tdk 2.7.1.21 F thymidine kinase
KKOJADAG_00312 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KKOJADAG_00313 7.1e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KKOJADAG_00314 2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KKOJADAG_00315 1.5e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KKOJADAG_00316 5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
KKOJADAG_00317 4.7e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKOJADAG_00318 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KKOJADAG_00319 9.8e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KKOJADAG_00320 6.7e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KKOJADAG_00321 1.6e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KKOJADAG_00322 9.6e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KKOJADAG_00323 2.4e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KKOJADAG_00324 2.4e-31 ywzB S Protein of unknown function (DUF1146)
KKOJADAG_00325 1.5e-178 mbl D Cell shape determining protein MreB Mrl
KKOJADAG_00326 6.8e-13 S DNA-directed RNA polymerase subunit beta
KKOJADAG_00327 2.6e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KKOJADAG_00328 6.6e-34 S Protein of unknown function (DUF2969)
KKOJADAG_00329 1.4e-223 rodA D Belongs to the SEDS family
KKOJADAG_00330 2.2e-56 yjdF S Protein of unknown function (DUF2992)
KKOJADAG_00331 3.9e-93 K Bacterial regulatory proteins, tetR family
KKOJADAG_00332 1.2e-111 1.6.5.2 S NADPH-dependent FMN reductase
KKOJADAG_00333 1e-171 K Helix-turn-helix
KKOJADAG_00334 2e-94 yxkA S Phosphatidylethanolamine-binding protein
KKOJADAG_00335 5.6e-107 K transcriptional regulator
KKOJADAG_00336 3.2e-12
KKOJADAG_00337 1.8e-28 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KKOJADAG_00338 3.7e-148 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KKOJADAG_00339 1.1e-56 hxlR K Transcriptional regulator, HxlR family
KKOJADAG_00340 3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KKOJADAG_00341 8e-132 K Psort location CytoplasmicMembrane, score
KKOJADAG_00342 1.2e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KKOJADAG_00343 3.5e-236 pbuX F xanthine permease
KKOJADAG_00344 2.9e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KKOJADAG_00345 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KKOJADAG_00346 2.5e-63 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KKOJADAG_00347 4e-69 S Domain of unknown function (DUF1934)
KKOJADAG_00348 5.1e-267 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
KKOJADAG_00349 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
KKOJADAG_00350 2.4e-153 malG P ABC transporter permease
KKOJADAG_00351 2.5e-253 malF P Binding-protein-dependent transport system inner membrane component
KKOJADAG_00352 2.8e-216 malE G Bacterial extracellular solute-binding protein
KKOJADAG_00353 2.3e-209 msmX P Belongs to the ABC transporter superfamily
KKOJADAG_00354 8.1e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KKOJADAG_00355 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KKOJADAG_00356 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KKOJADAG_00357 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
KKOJADAG_00358 3.8e-176 yvdE K helix_turn _helix lactose operon repressor
KKOJADAG_00359 1.1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KKOJADAG_00360 4.1e-219 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KKOJADAG_00361 1.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KKOJADAG_00362 2.2e-35 veg S Biofilm formation stimulator VEG
KKOJADAG_00363 1.2e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KKOJADAG_00364 1.2e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KKOJADAG_00365 3.6e-148 tatD L hydrolase, TatD family
KKOJADAG_00366 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KKOJADAG_00367 8.5e-182 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KKOJADAG_00368 4e-99 S TPM domain
KKOJADAG_00369 5.6e-91 comEB 3.5.4.12 F MafB19-like deaminase
KKOJADAG_00370 1.2e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KKOJADAG_00371 1.2e-114 E Belongs to the SOS response-associated peptidase family
KKOJADAG_00373 1.8e-116
KKOJADAG_00374 5.5e-158 ypbG 2.7.1.2 GK ROK family
KKOJADAG_00375 1.8e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKOJADAG_00376 4.6e-263 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKOJADAG_00377 2.6e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
KKOJADAG_00378 2.1e-41
KKOJADAG_00379 1.5e-50 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
KKOJADAG_00380 2.1e-134 gmuR K UTRA
KKOJADAG_00381 3.1e-305 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKOJADAG_00382 4.6e-70 S Domain of unknown function (DUF3284)
KKOJADAG_00383 5.2e-130 yydK K UTRA
KKOJADAG_00384 8.2e-241 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKOJADAG_00385 7.5e-83
KKOJADAG_00386 2.4e-291 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKOJADAG_00387 2.2e-51 hsp O Belongs to the small heat shock protein (HSP20) family
KKOJADAG_00388 9.1e-75 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KKOJADAG_00389 3.8e-31
KKOJADAG_00390 3.7e-254 pepC 3.4.22.40 E aminopeptidase
KKOJADAG_00391 9.8e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KKOJADAG_00392 4.8e-131 oppF P Belongs to the ABC transporter superfamily
KKOJADAG_00393 4.4e-170 oppD P Belongs to the ABC transporter superfamily
KKOJADAG_00394 6.2e-148 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKOJADAG_00395 3.9e-125 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KKOJADAG_00396 1.1e-137 oppA E ABC transporter, substratebinding protein
KKOJADAG_00397 3.3e-48 oppA E ABC transporter, substratebinding protein
KKOJADAG_00398 2.1e-257 pepC 3.4.22.40 E aminopeptidase
KKOJADAG_00400 4.8e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KKOJADAG_00401 0.0 XK27_08315 M Sulfatase
KKOJADAG_00402 1.9e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KKOJADAG_00403 2.3e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KKOJADAG_00404 2.2e-170 yqhA G Aldose 1-epimerase
KKOJADAG_00405 1.2e-152 glcU U sugar transport
KKOJADAG_00406 1.2e-118
KKOJADAG_00407 8e-179 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KKOJADAG_00408 3.4e-71 2.4.1.83 GT2 S GtrA-like protein
KKOJADAG_00409 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KKOJADAG_00410 2.1e-45 S HicB_like antitoxin of bacterial toxin-antitoxin system
KKOJADAG_00411 1.1e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KKOJADAG_00412 2.4e-74 S PAS domain
KKOJADAG_00413 2.9e-148
KKOJADAG_00414 9.5e-141
KKOJADAG_00415 1.4e-178 S Oxidoreductase family, NAD-binding Rossmann fold
KKOJADAG_00416 0.0 yjbQ P TrkA C-terminal domain protein
KKOJADAG_00417 3.6e-143 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
KKOJADAG_00418 7.1e-57 lysA2 M Glycosyl hydrolases family 25
KKOJADAG_00419 7.7e-214 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KKOJADAG_00420 8.2e-35 S Protein of unknown function (DUF2922)
KKOJADAG_00421 4.2e-27
KKOJADAG_00422 5.5e-115
KKOJADAG_00423 1e-72
KKOJADAG_00424 0.0 kup P Transport of potassium into the cell
KKOJADAG_00425 0.0 kup P Transport of potassium into the cell
KKOJADAG_00426 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KKOJADAG_00427 0.0 S Bacterial membrane protein, YfhO
KKOJADAG_00428 0.0 pepO 3.4.24.71 O Peptidase family M13
KKOJADAG_00429 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KKOJADAG_00430 1.3e-168 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
KKOJADAG_00431 2.6e-135 rpl K Helix-turn-helix domain, rpiR family
KKOJADAG_00432 5.3e-184 D nuclear chromosome segregation
KKOJADAG_00433 1.5e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
KKOJADAG_00434 1.2e-227 yttB EGP Major facilitator Superfamily
KKOJADAG_00435 6.4e-229 XK27_04775 S PAS domain
KKOJADAG_00436 7e-104 S Iron-sulfur cluster assembly protein
KKOJADAG_00437 3.1e-130 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KKOJADAG_00438 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KKOJADAG_00439 3.3e-266 yxbA 6.3.1.12 S ATP-grasp enzyme
KKOJADAG_00440 0.0 asnB 6.3.5.4 E Asparagine synthase
KKOJADAG_00441 4e-275 S Calcineurin-like phosphoesterase
KKOJADAG_00442 1.9e-83
KKOJADAG_00443 7.1e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KKOJADAG_00444 5.4e-131 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KKOJADAG_00445 1.9e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KKOJADAG_00446 9.8e-169 phnD P Phosphonate ABC transporter
KKOJADAG_00448 1e-87 uspA T universal stress protein
KKOJADAG_00449 3.4e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
KKOJADAG_00450 1.1e-130 XK27_08440 K UTRA domain
KKOJADAG_00451 3.4e-100 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KKOJADAG_00452 4.8e-87 ntd 2.4.2.6 F Nucleoside
KKOJADAG_00453 1.2e-219 S zinc-ribbon domain
KKOJADAG_00454 3.6e-67 2.7.1.191 G PTS system fructose IIA component
KKOJADAG_00455 7.1e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
KKOJADAG_00456 3.4e-129 XK27_08455 G PTS system sorbose-specific iic component
KKOJADAG_00457 6.7e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
KKOJADAG_00458 1.4e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KKOJADAG_00459 5.5e-217 agaS G SIS domain
KKOJADAG_00460 1.5e-129 XK27_08435 K UTRA
KKOJADAG_00461 0.0 G Belongs to the glycosyl hydrolase 31 family
KKOJADAG_00462 2.8e-154 I alpha/beta hydrolase fold
KKOJADAG_00463 1.2e-119 yibF S overlaps another CDS with the same product name
KKOJADAG_00464 8.9e-169 yibE S overlaps another CDS with the same product name
KKOJADAG_00465 1.2e-270 yjcE P Sodium proton antiporter
KKOJADAG_00466 6.8e-77
KKOJADAG_00467 4.8e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KKOJADAG_00468 8.3e-266 S Cysteine-rich secretory protein family
KKOJADAG_00469 4.2e-126
KKOJADAG_00470 7.6e-115 luxT K Bacterial regulatory proteins, tetR family
KKOJADAG_00471 1.6e-239 cycA E Amino acid permease
KKOJADAG_00472 1.6e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KKOJADAG_00473 9.1e-62
KKOJADAG_00474 1.1e-124 S Alpha/beta hydrolase family
KKOJADAG_00475 8e-154 epsV 2.7.8.12 S glycosyl transferase family 2
KKOJADAG_00476 4.8e-158 ypuA S Protein of unknown function (DUF1002)
KKOJADAG_00478 7.7e-140 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KKOJADAG_00479 2.2e-176 S Alpha/beta hydrolase of unknown function (DUF915)
KKOJADAG_00480 2.1e-123 yugP S Putative neutral zinc metallopeptidase
KKOJADAG_00481 4.8e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KKOJADAG_00482 2.6e-80
KKOJADAG_00483 5.1e-133 cobB K SIR2 family
KKOJADAG_00484 9.2e-87 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
KKOJADAG_00485 3.6e-124 terC P Integral membrane protein TerC family
KKOJADAG_00486 4.4e-64 yeaO S Protein of unknown function, DUF488
KKOJADAG_00487 5e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KKOJADAG_00488 6.4e-301 glnP P ABC transporter permease
KKOJADAG_00489 7.3e-138 glnQ E ABC transporter, ATP-binding protein
KKOJADAG_00490 2e-45
KKOJADAG_00491 3.7e-176 L HNH nucleases
KKOJADAG_00492 4.5e-120 yfbR S HD containing hydrolase-like enzyme
KKOJADAG_00493 8.1e-210 G Glycosyl hydrolases family 8
KKOJADAG_00494 3.7e-246 ydaM M Glycosyl transferase
KKOJADAG_00496 5.6e-118
KKOJADAG_00497 1.7e-16
KKOJADAG_00498 3.5e-70 S Iron-sulphur cluster biosynthesis
KKOJADAG_00499 6e-181 ybiR P Citrate transporter
KKOJADAG_00500 3.2e-90 lemA S LemA family
KKOJADAG_00501 2e-163 htpX O Belongs to the peptidase M48B family
KKOJADAG_00502 2.8e-168 K helix_turn_helix, arabinose operon control protein
KKOJADAG_00503 6.1e-97 S ABC-type cobalt transport system, permease component
KKOJADAG_00504 6.2e-249 cbiO1 S ABC transporter, ATP-binding protein
KKOJADAG_00505 2.1e-109 P Cobalt transport protein
KKOJADAG_00506 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KKOJADAG_00507 6.4e-176 htrA 3.4.21.107 O serine protease
KKOJADAG_00508 1.1e-147 vicX 3.1.26.11 S domain protein
KKOJADAG_00509 6.7e-145 yycI S YycH protein
KKOJADAG_00510 3e-251 yycH S YycH protein
KKOJADAG_00511 0.0 vicK 2.7.13.3 T Histidine kinase
KKOJADAG_00512 1.5e-129 K response regulator
KKOJADAG_00514 2.5e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KKOJADAG_00515 2.3e-101 J Acetyltransferase (GNAT) domain
KKOJADAG_00516 5.3e-107 yjbF S SNARE associated Golgi protein
KKOJADAG_00517 6.3e-156 I alpha/beta hydrolase fold
KKOJADAG_00518 5.6e-155 hipB K Helix-turn-helix
KKOJADAG_00519 4.2e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KKOJADAG_00520 1.6e-177
KKOJADAG_00521 9.9e-126 S SNARE associated Golgi protein
KKOJADAG_00522 1.3e-145 cof S haloacid dehalogenase-like hydrolase
KKOJADAG_00523 0.0 ydgH S MMPL family
KKOJADAG_00524 1.1e-95 yobS K Bacterial regulatory proteins, tetR family
KKOJADAG_00525 1.9e-159 3.5.2.6 V Beta-lactamase enzyme family
KKOJADAG_00526 2e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
KKOJADAG_00527 1.1e-82 yjcF S Acetyltransferase (GNAT) domain
KKOJADAG_00528 1.1e-92 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KKOJADAG_00529 3.9e-78 yybA 2.3.1.57 K Transcriptional regulator
KKOJADAG_00530 2.9e-39 ypaA S Protein of unknown function (DUF1304)
KKOJADAG_00531 2.5e-239 G Bacterial extracellular solute-binding protein
KKOJADAG_00532 5.1e-248 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
KKOJADAG_00533 1.1e-147 gtsC P Binding-protein-dependent transport system inner membrane component
KKOJADAG_00534 2.1e-157 gtsB P ABC-type sugar transport systems, permease components
KKOJADAG_00535 3.8e-204 malK P ATPases associated with a variety of cellular activities
KKOJADAG_00536 3.3e-280 pipD E Dipeptidase
KKOJADAG_00537 7.6e-152 endA F DNA RNA non-specific endonuclease
KKOJADAG_00538 2.9e-156 dkg S reductase
KKOJADAG_00539 9.3e-198 ltrA S Bacterial low temperature requirement A protein (LtrA)
KKOJADAG_00540 3e-181 dnaQ 2.7.7.7 L EXOIII
KKOJADAG_00541 3e-150 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KKOJADAG_00542 4.4e-112 yviA S Protein of unknown function (DUF421)
KKOJADAG_00543 2e-74 S Protein of unknown function (DUF3290)
KKOJADAG_00544 3.5e-241 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KKOJADAG_00545 2.1e-91 S PAS domain
KKOJADAG_00546 5.3e-144 pnuC H nicotinamide mononucleotide transporter
KKOJADAG_00547 3.1e-97 M LysM domain protein
KKOJADAG_00549 2.5e-31 yjgN S Bacterial protein of unknown function (DUF898)
KKOJADAG_00550 1.9e-36 K SIS domain
KKOJADAG_00551 9.9e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
KKOJADAG_00554 1.9e-52 P Rhodanese Homology Domain
KKOJADAG_00555 2.7e-189
KKOJADAG_00556 3.6e-123 gntR1 K UTRA
KKOJADAG_00557 7.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
KKOJADAG_00558 1.6e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KKOJADAG_00559 4.9e-207 csaB M Glycosyl transferases group 1
KKOJADAG_00560 0.0 S Glycosyltransferase like family 2
KKOJADAG_00561 6.5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KKOJADAG_00562 5.5e-155 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KKOJADAG_00563 0.0 spoVK O ATPase family associated with various cellular activities (AAA)
KKOJADAG_00564 0.0 pacL 3.6.3.8 P P-type ATPase
KKOJADAG_00565 1.5e-286 V ABC transporter transmembrane region
KKOJADAG_00566 2.8e-135
KKOJADAG_00567 3.4e-227 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KKOJADAG_00568 5.1e-257 epsU S Polysaccharide biosynthesis protein
KKOJADAG_00569 1.2e-131 M Glycosyltransferase sugar-binding region containing DXD motif
KKOJADAG_00570 1.8e-83 ydcK S Belongs to the SprT family
KKOJADAG_00572 6.2e-103 S ECF transporter, substrate-specific component
KKOJADAG_00573 2.3e-113 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
KKOJADAG_00574 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KKOJADAG_00575 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KKOJADAG_00576 1.9e-206 camS S sex pheromone
KKOJADAG_00577 3.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KKOJADAG_00578 5.2e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KKOJADAG_00579 6e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KKOJADAG_00580 6.9e-167 yegS 2.7.1.107 G Lipid kinase
KKOJADAG_00581 5.7e-85 tlpA2 L Transposase IS200 like
KKOJADAG_00582 6.6e-251 L transposase, IS605 OrfB family
KKOJADAG_00583 3.8e-148 S hydrolase
KKOJADAG_00585 6.9e-124 infB UW LPXTG-motif cell wall anchor domain protein
KKOJADAG_00586 0.0 3.1.31.1 M domain protein
KKOJADAG_00587 7.8e-299 E amino acid
KKOJADAG_00588 3.6e-171 K LysR substrate binding domain
KKOJADAG_00589 0.0 1.3.5.4 C FAD binding domain
KKOJADAG_00590 3.4e-242 brnQ U Component of the transport system for branched-chain amino acids
KKOJADAG_00591 2.1e-134 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KKOJADAG_00592 1.6e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KKOJADAG_00593 1.2e-63 S Peptidase propeptide and YPEB domain
KKOJADAG_00594 2.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KKOJADAG_00595 2.2e-249 yhjX_2 P Major Facilitator Superfamily
KKOJADAG_00596 1e-246 yhjX_2 P Major Facilitator Superfamily
KKOJADAG_00597 4.7e-165 arbZ I Phosphate acyltransferases
KKOJADAG_00598 1.4e-186 arbY M Glycosyl transferase family 8
KKOJADAG_00599 1.1e-183 arbY M Glycosyl transferase family 8
KKOJADAG_00600 1.6e-154 arbx M Glycosyl transferase family 8
KKOJADAG_00601 3e-147 arbV 2.3.1.51 I Acyl-transferase
KKOJADAG_00603 1.9e-32 UW Tetratricopeptide repeat
KKOJADAG_00604 2.9e-75 M lipopolysaccharide 3-alpha-galactosyltransferase activity
KKOJADAG_00605 4.5e-227 M Pfam:DUF1792
KKOJADAG_00606 0.0 GT2,GT4 M family 8
KKOJADAG_00607 0.0 GT2,GT4 M family 8
KKOJADAG_00608 2.1e-118 ybhL S Belongs to the BI1 family
KKOJADAG_00609 4.1e-142 cbiQ P cobalt transport
KKOJADAG_00610 0.0 ykoD P ABC transporter, ATP-binding protein
KKOJADAG_00611 1.9e-95 S UPF0397 protein
KKOJADAG_00612 3.4e-160 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
KKOJADAG_00613 1.1e-243 nhaC C Na H antiporter NhaC
KKOJADAG_00614 2e-129 mutF V ABC transporter, ATP-binding protein
KKOJADAG_00615 2.1e-120 spaE S ABC-2 family transporter protein
KKOJADAG_00616 1.5e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KKOJADAG_00617 1.6e-108
KKOJADAG_00618 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KKOJADAG_00619 7.9e-35 copZ C Heavy-metal-associated domain
KKOJADAG_00620 1.1e-92 dps P Belongs to the Dps family
KKOJADAG_00621 8.1e-114 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KKOJADAG_00622 1.8e-37 ung2 3.2.2.27 L Uracil-DNA glycosylase
KKOJADAG_00624 1.7e-198 V Beta-lactamase
KKOJADAG_00625 4.6e-151 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
KKOJADAG_00626 7.9e-157 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KKOJADAG_00627 6.6e-96
KKOJADAG_00628 3.2e-65 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
KKOJADAG_00629 3.6e-123 L restriction endonuclease
KKOJADAG_00630 2.1e-134 mrr L restriction endonuclease
KKOJADAG_00631 1.6e-62 2.5.1.74 H UbiA prenyltransferase family
KKOJADAG_00632 1.9e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KKOJADAG_00633 6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KKOJADAG_00634 5.8e-115 hlyIII S protein, hemolysin III
KKOJADAG_00635 4.7e-149 DegV S Uncharacterised protein, DegV family COG1307
KKOJADAG_00636 1.6e-35 yozE S Belongs to the UPF0346 family
KKOJADAG_00637 3.1e-262 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KKOJADAG_00638 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KKOJADAG_00639 1.8e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KKOJADAG_00640 1.1e-153 dprA LU DNA protecting protein DprA
KKOJADAG_00641 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KKOJADAG_00642 1.5e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KKOJADAG_00643 1.3e-168 xerC D Phage integrase, N-terminal SAM-like domain
KKOJADAG_00644 4.3e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KKOJADAG_00645 8.2e-252 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KKOJADAG_00646 1.1e-177 lacX 5.1.3.3 G Aldose 1-epimerase
KKOJADAG_00647 2.3e-97 K LysR substrate binding domain
KKOJADAG_00648 1.2e-100 S LexA-binding, inner membrane-associated putative hydrolase
KKOJADAG_00650 1.9e-72
KKOJADAG_00651 2.6e-178 MA20_14895 S Conserved hypothetical protein 698
KKOJADAG_00652 5.3e-273 lsa S ABC transporter
KKOJADAG_00653 4.1e-83 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
KKOJADAG_00654 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KKOJADAG_00655 1.1e-135 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
KKOJADAG_00656 3.8e-64 S Protein of unknown function (DUF3021)
KKOJADAG_00657 2.6e-71 K LytTr DNA-binding domain
KKOJADAG_00658 0.0 sprD D Domain of Unknown Function (DUF1542)
KKOJADAG_00659 8.4e-109 S Protein of unknown function (DUF1211)
KKOJADAG_00660 8.6e-12 S reductase
KKOJADAG_00661 3e-55 S reductase
KKOJADAG_00662 7.4e-109 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KKOJADAG_00663 2e-117 3.6.1.55 F NUDIX domain
KKOJADAG_00664 8.2e-128 T Transcriptional regulatory protein, C terminal
KKOJADAG_00665 3.4e-239 T GHKL domain
KKOJADAG_00666 2.4e-89 S Peptidase propeptide and YPEB domain
KKOJADAG_00667 4.4e-123 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KKOJADAG_00668 2.7e-25 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KKOJADAG_00669 2.4e-72 S Putative adhesin
KKOJADAG_00670 2.1e-244 brnQ U Component of the transport system for branched-chain amino acids
KKOJADAG_00671 1.7e-145 sufC O FeS assembly ATPase SufC
KKOJADAG_00672 2.7e-227 sufD O FeS assembly protein SufD
KKOJADAG_00673 7.5e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KKOJADAG_00674 2.7e-79 nifU C SUF system FeS assembly protein, NifU family
KKOJADAG_00675 3.4e-274 sufB O assembly protein SufB
KKOJADAG_00676 6.2e-54 yitW S Iron-sulfur cluster assembly protein
KKOJADAG_00677 4.6e-269 mntH P H( )-stimulated, divalent metal cation uptake system
KKOJADAG_00678 3.4e-140 H Nodulation protein S (NodS)
KKOJADAG_00680 2.6e-115 papP P ABC transporter, permease protein
KKOJADAG_00681 1.3e-106 P ABC transporter permease
KKOJADAG_00682 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KKOJADAG_00683 7.2e-142 cjaA ET ABC transporter substrate-binding protein
KKOJADAG_00684 7.1e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
KKOJADAG_00685 4.6e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KKOJADAG_00686 9.2e-247 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KKOJADAG_00687 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
KKOJADAG_00688 1.1e-101 skfE V ATPases associated with a variety of cellular activities
KKOJADAG_00689 3.5e-146
KKOJADAG_00690 4.1e-142
KKOJADAG_00691 5.4e-36 L PFAM Integrase catalytic region
KKOJADAG_00692 5.8e-149
KKOJADAG_00694 3.7e-288 V ABC transporter transmembrane region
KKOJADAG_00695 2.9e-39
KKOJADAG_00696 1.1e-62
KKOJADAG_00697 1.4e-14 ywnB S NAD(P)H-binding
KKOJADAG_00698 1.5e-75 L transposase activity
KKOJADAG_00699 4.7e-22
KKOJADAG_00700 1.4e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KKOJADAG_00701 2.4e-130
KKOJADAG_00702 1.4e-173
KKOJADAG_00703 3.9e-262 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
KKOJADAG_00704 8.5e-51 ybjQ S Belongs to the UPF0145 family
KKOJADAG_00705 4.2e-176 XK27_05540 S DUF218 domain
KKOJADAG_00706 1.2e-149 yxeH S hydrolase
KKOJADAG_00707 2e-302 I Protein of unknown function (DUF2974)
KKOJADAG_00708 1.2e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KKOJADAG_00709 9.9e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KKOJADAG_00710 5.7e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KKOJADAG_00711 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KKOJADAG_00712 1.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KKOJADAG_00713 3.1e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KKOJADAG_00714 2.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KKOJADAG_00715 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KKOJADAG_00716 2.8e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KKOJADAG_00717 2.9e-104 pncA Q Isochorismatase family
KKOJADAG_00718 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KKOJADAG_00719 8.4e-215 M Glycosyl transferases group 1
KKOJADAG_00720 3.4e-143 N Uncharacterized conserved protein (DUF2075)
KKOJADAG_00721 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KKOJADAG_00722 1.3e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKOJADAG_00723 2.5e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KKOJADAG_00724 5.2e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
KKOJADAG_00725 1.9e-112 yjbK S CYTH
KKOJADAG_00726 3.7e-108 yjbH Q Thioredoxin
KKOJADAG_00727 8.2e-165 coiA 3.6.4.12 S Competence protein
KKOJADAG_00728 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KKOJADAG_00729 5.2e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KKOJADAG_00730 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KKOJADAG_00731 4.2e-40 ptsH G phosphocarrier protein HPR
KKOJADAG_00732 5.9e-25
KKOJADAG_00733 0.0 clpE O Belongs to the ClpA ClpB family
KKOJADAG_00734 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
KKOJADAG_00735 5.1e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KKOJADAG_00736 3.6e-157 hlyX S Transporter associated domain
KKOJADAG_00737 1.5e-77
KKOJADAG_00738 1.8e-89
KKOJADAG_00739 2e-64 ygaC J Belongs to the UPF0374 family
KKOJADAG_00740 4.5e-24 ygaC J Belongs to the UPF0374 family
KKOJADAG_00741 1.6e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
KKOJADAG_00742 1e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KKOJADAG_00743 2.4e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KKOJADAG_00744 5e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KKOJADAG_00745 1.4e-217 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
KKOJADAG_00746 1.9e-180 D Alpha beta
KKOJADAG_00748 1.1e-152 S haloacid dehalogenase-like hydrolase
KKOJADAG_00749 5.3e-204 EGP Major facilitator Superfamily
KKOJADAG_00750 7.1e-261 glnA 6.3.1.2 E glutamine synthetase
KKOJADAG_00751 1.8e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KKOJADAG_00752 8.1e-19 S Protein of unknown function (DUF3042)
KKOJADAG_00753 5.1e-58 yqhL P Rhodanese-like protein
KKOJADAG_00754 7.9e-35 yqgQ S Bacterial protein of unknown function (DUF910)
KKOJADAG_00755 4e-119 gluP 3.4.21.105 S Rhomboid family
KKOJADAG_00756 3.6e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KKOJADAG_00757 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KKOJADAG_00758 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KKOJADAG_00759 0.0 S membrane
KKOJADAG_00760 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KKOJADAG_00761 3.2e-203 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KKOJADAG_00762 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KKOJADAG_00763 2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KKOJADAG_00764 1.8e-62 yodB K Transcriptional regulator, HxlR family
KKOJADAG_00765 2.8e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKOJADAG_00766 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KKOJADAG_00767 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KKOJADAG_00768 4.6e-280 arlS 2.7.13.3 T Histidine kinase
KKOJADAG_00769 1.1e-130 K response regulator
KKOJADAG_00770 4.2e-95 yceD S Uncharacterized ACR, COG1399
KKOJADAG_00771 1.9e-217 ylbM S Belongs to the UPF0348 family
KKOJADAG_00772 3.7e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KKOJADAG_00773 1.9e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KKOJADAG_00774 1.7e-119 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KKOJADAG_00775 3.6e-210 yqeH S Ribosome biogenesis GTPase YqeH
KKOJADAG_00776 2.4e-87 yqeG S HAD phosphatase, family IIIA
KKOJADAG_00777 1.9e-189 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KKOJADAG_00778 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KKOJADAG_00779 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KKOJADAG_00780 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KKOJADAG_00781 8.6e-237 S CAAX protease self-immunity
KKOJADAG_00782 1.6e-73 S Protein of unknown function (DUF3021)
KKOJADAG_00783 1.1e-74 K LytTr DNA-binding domain
KKOJADAG_00784 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KKOJADAG_00785 5.4e-156 dnaI L Primosomal protein DnaI
KKOJADAG_00786 3.2e-237 dnaB L Replication initiation and membrane attachment
KKOJADAG_00787 7.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KKOJADAG_00788 6e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KKOJADAG_00789 5.7e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KKOJADAG_00790 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KKOJADAG_00791 6e-61 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KKOJADAG_00792 6.5e-120 K UTRA
KKOJADAG_00793 4.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KKOJADAG_00794 1.6e-85 cutC P Participates in the control of copper homeostasis
KKOJADAG_00795 1.5e-120 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KKOJADAG_00796 4.7e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KKOJADAG_00797 1.1e-62
KKOJADAG_00798 8.9e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KKOJADAG_00799 5.8e-222 ecsB U ABC transporter
KKOJADAG_00800 9.7e-135 ecsA V ABC transporter, ATP-binding protein
KKOJADAG_00801 3.5e-76 hit FG Scavenger mRNA decapping enzyme C-term binding
KKOJADAG_00802 2e-51
KKOJADAG_00803 9.5e-24 S YtxH-like protein
KKOJADAG_00804 4.9e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KKOJADAG_00805 3e-184 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
KKOJADAG_00806 0.0 L AAA domain
KKOJADAG_00807 1.9e-220 yhaO L Ser Thr phosphatase family protein
KKOJADAG_00808 9.5e-56 yheA S Belongs to the UPF0342 family
KKOJADAG_00809 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KKOJADAG_00810 9e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKOJADAG_00812 0.0 GH23 S M26 IgA1-specific Metallo-endopeptidase C-terminal region
KKOJADAG_00813 8e-45 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
KKOJADAG_00814 3.4e-11 G PTS system sugar-specific permease component
KKOJADAG_00815 7.2e-220 G PTS system sugar-specific permease component
KKOJADAG_00816 2.3e-78 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KKOJADAG_00817 3.1e-69 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KKOJADAG_00818 8.7e-116 manR K PRD domain
KKOJADAG_00819 1.1e-251 yfnA E Amino Acid
KKOJADAG_00820 0.0 clpE2 O AAA domain (Cdc48 subfamily)
KKOJADAG_00821 5.5e-172 S Alpha/beta hydrolase of unknown function (DUF915)
KKOJADAG_00822 1.6e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKOJADAG_00823 5.4e-39
KKOJADAG_00824 2.8e-216 lmrP E Major Facilitator Superfamily
KKOJADAG_00825 1.2e-146 pbpX2 V Beta-lactamase
KKOJADAG_00826 9e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KKOJADAG_00827 6.7e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKOJADAG_00828 6.1e-235 dltB M MBOAT, membrane-bound O-acyltransferase family
KKOJADAG_00829 1.9e-291 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KKOJADAG_00831 3.9e-39
KKOJADAG_00832 8.9e-204 ywhK S Membrane
KKOJADAG_00834 5.7e-59
KKOJADAG_00835 1.1e-49
KKOJADAG_00836 2.1e-45
KKOJADAG_00837 2.7e-85 ykuL S (CBS) domain
KKOJADAG_00838 0.0 cadA P P-type ATPase
KKOJADAG_00839 4.9e-202 napA P Sodium/hydrogen exchanger family
KKOJADAG_00840 1e-95 S Putative adhesin
KKOJADAG_00841 9.1e-284 V ABC transporter transmembrane region
KKOJADAG_00842 1.6e-160 mutR K Helix-turn-helix XRE-family like proteins
KKOJADAG_00843 3.5e-35
KKOJADAG_00844 1.7e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KKOJADAG_00845 3.5e-158 S Protein of unknown function (DUF979)
KKOJADAG_00846 6.6e-114 S Protein of unknown function (DUF969)
KKOJADAG_00847 6.5e-87 S Protein of unknown function (DUF805)
KKOJADAG_00849 4.1e-15
KKOJADAG_00850 8.5e-268 G PTS system Galactitol-specific IIC component
KKOJADAG_00851 6.1e-96 S Protein of unknown function (DUF1440)
KKOJADAG_00852 1.8e-105 S CAAX protease self-immunity
KKOJADAG_00853 1e-204 S DUF218 domain
KKOJADAG_00854 0.0 macB_3 V ABC transporter, ATP-binding protein
KKOJADAG_00855 6.2e-268 cydA 1.10.3.14 C ubiquinol oxidase
KKOJADAG_00856 2.4e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KKOJADAG_00857 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KKOJADAG_00858 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KKOJADAG_00859 1.2e-177 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KKOJADAG_00860 8.3e-168 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
KKOJADAG_00861 1.9e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
KKOJADAG_00862 1.9e-150 K Helix-turn-helix domain, rpiR family
KKOJADAG_00863 6.6e-169 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KKOJADAG_00864 4.4e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KKOJADAG_00865 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKOJADAG_00866 1.9e-130 S membrane transporter protein
KKOJADAG_00867 6.2e-162 yeaE S Aldo/keto reductase family
KKOJADAG_00868 2.3e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KKOJADAG_00869 1e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KKOJADAG_00870 6.3e-125 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KKOJADAG_00871 3.3e-236 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KKOJADAG_00872 3e-232 pbuG S permease
KKOJADAG_00873 7.9e-129 K helix_turn_helix, mercury resistance
KKOJADAG_00874 5.7e-231 pbuG S permease
KKOJADAG_00875 4.2e-226 pbuG S permease
KKOJADAG_00876 3.9e-76 K Bacteriophage CI repressor helix-turn-helix domain
KKOJADAG_00877 1.1e-68 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KKOJADAG_00878 2.3e-72
KKOJADAG_00879 1.4e-90
KKOJADAG_00880 4.3e-74 atkY K Penicillinase repressor
KKOJADAG_00881 2.7e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KKOJADAG_00882 2.2e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KKOJADAG_00883 0.0 copA 3.6.3.54 P P-type ATPase
KKOJADAG_00884 1.8e-61 UW LPXTG-motif cell wall anchor domain protein
KKOJADAG_00885 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
KKOJADAG_00886 2e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KKOJADAG_00887 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KKOJADAG_00888 0.0 KLT serine threonine protein kinase
KKOJADAG_00889 4.5e-140 stp 3.1.3.16 T phosphatase
KKOJADAG_00890 7.5e-239 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KKOJADAG_00891 7.4e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KKOJADAG_00892 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KKOJADAG_00893 2.3e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KKOJADAG_00894 7.3e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KKOJADAG_00895 1e-47
KKOJADAG_00896 8.5e-296 recN L May be involved in recombinational repair of damaged DNA
KKOJADAG_00897 4.6e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KKOJADAG_00898 1.5e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KKOJADAG_00899 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KKOJADAG_00900 7.2e-253 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KKOJADAG_00901 3.9e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KKOJADAG_00902 3.6e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KKOJADAG_00903 8.2e-73 yqhY S Asp23 family, cell envelope-related function
KKOJADAG_00904 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KKOJADAG_00905 6.4e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KKOJADAG_00906 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KKOJADAG_00907 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KKOJADAG_00908 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
KKOJADAG_00909 2.9e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KKOJADAG_00910 1.5e-215 S Uncharacterized protein conserved in bacteria (DUF2325)
KKOJADAG_00911 3.5e-12
KKOJADAG_00912 6.3e-64
KKOJADAG_00913 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KKOJADAG_00914 9e-93 S ECF-type riboflavin transporter, S component
KKOJADAG_00915 5e-148 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KKOJADAG_00916 9.7e-85
KKOJADAG_00917 4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KKOJADAG_00918 0.0 S Predicted membrane protein (DUF2207)
KKOJADAG_00919 1.2e-176 I Carboxylesterase family
KKOJADAG_00920 3.5e-43 rhaS6 K helix_turn_helix, arabinose operon control protein
KKOJADAG_00921 2.9e-62 K AraC-like ligand binding domain
KKOJADAG_00922 3.1e-133 2.7.1.2 GK ROK family
KKOJADAG_00923 7.8e-10 2.7.1.2 GK ROK family
KKOJADAG_00924 1.2e-80 3.4.22.70 M Sortase family
KKOJADAG_00927 7.9e-257 pepC 3.4.22.40 E Peptidase C1-like family
KKOJADAG_00928 4.6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
KKOJADAG_00929 0.0 oppA E ABC transporter substrate-binding protein
KKOJADAG_00930 1.9e-77 K MerR HTH family regulatory protein
KKOJADAG_00931 4.7e-266 lmrB EGP Major facilitator Superfamily
KKOJADAG_00932 6e-97 S Domain of unknown function (DUF4811)
KKOJADAG_00933 2.5e-141 ppm1 GT2 M Glycosyl transferase family 2
KKOJADAG_00934 3.2e-107 fic D Fic/DOC family
KKOJADAG_00935 1.1e-69
KKOJADAG_00936 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KKOJADAG_00937 2e-294 V ABC transporter transmembrane region
KKOJADAG_00939 2.8e-145 S haloacid dehalogenase-like hydrolase
KKOJADAG_00940 0.0 pepN 3.4.11.2 E aminopeptidase
KKOJADAG_00941 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KKOJADAG_00942 1.7e-227 sptS 2.7.13.3 T Histidine kinase
KKOJADAG_00943 1.8e-116 K response regulator
KKOJADAG_00944 3.5e-114 2.7.6.5 T Region found in RelA / SpoT proteins
KKOJADAG_00945 2.8e-163 ltrA S Bacterial low temperature requirement A protein (LtrA)
KKOJADAG_00946 2.5e-68 O OsmC-like protein
KKOJADAG_00947 9.6e-286 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KKOJADAG_00948 1.8e-181 E ABC transporter, ATP-binding protein
KKOJADAG_00949 1.2e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KKOJADAG_00950 1.1e-161 yihY S Belongs to the UPF0761 family
KKOJADAG_00951 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
KKOJADAG_00952 2.5e-77 fld C Flavodoxin
KKOJADAG_00953 3.6e-88 gtcA S Teichoic acid glycosylation protein
KKOJADAG_00954 5.5e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KKOJADAG_00957 2.3e-251 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKOJADAG_00958 2.7e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
KKOJADAG_00959 7.6e-137 M Glycosyl hydrolases family 25
KKOJADAG_00960 8e-233 potE E amino acid
KKOJADAG_00961 9.8e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KKOJADAG_00962 1.1e-237 yhdP S Transporter associated domain
KKOJADAG_00963 2.1e-131
KKOJADAG_00964 1.3e-119 C nitroreductase
KKOJADAG_00965 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KKOJADAG_00966 4.7e-140 glcR K DeoR C terminal sensor domain
KKOJADAG_00967 3.5e-52 S Enterocin A Immunity
KKOJADAG_00968 8.9e-133 gntR K UbiC transcription regulator-associated domain protein
KKOJADAG_00969 8.2e-176 rihB 3.2.2.1 F Nucleoside
KKOJADAG_00970 3.1e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KKOJADAG_00971 2.7e-158 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KKOJADAG_00972 2.6e-85 dps P Belongs to the Dps family
KKOJADAG_00973 4.6e-280 S C4-dicarboxylate anaerobic carrier
KKOJADAG_00974 1.9e-108 phoU P Plays a role in the regulation of phosphate uptake
KKOJADAG_00975 3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KKOJADAG_00976 6.3e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KKOJADAG_00977 3.7e-157 pstA P Phosphate transport system permease protein PstA
KKOJADAG_00978 1.2e-161 pstC P probably responsible for the translocation of the substrate across the membrane
KKOJADAG_00979 7.8e-160 pstS P Phosphate
KKOJADAG_00980 2.8e-96 K Acetyltransferase (GNAT) domain
KKOJADAG_00981 3.2e-130 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KKOJADAG_00982 1.5e-256 glnPH2 P ABC transporter permease
KKOJADAG_00983 3.6e-162 rssA S Phospholipase, patatin family
KKOJADAG_00984 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
KKOJADAG_00986 1.8e-53 S Enterocin A Immunity
KKOJADAG_00990 9.1e-223 S CAAX protease self-immunity
KKOJADAG_00991 1.3e-45 S Enterocin A Immunity
KKOJADAG_00993 2.4e-99 M Transport protein ComB
KKOJADAG_00994 9.1e-34 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KKOJADAG_00995 6e-79 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
KKOJADAG_00996 9.7e-24 L oxidized base lesion DNA N-glycosylase activity
KKOJADAG_00997 3e-98 L oxidized base lesion DNA N-glycosylase activity
KKOJADAG_00998 4.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KKOJADAG_00999 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KKOJADAG_01000 1.4e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KKOJADAG_01001 9.1e-248 clcA P chloride
KKOJADAG_01002 1.6e-114
KKOJADAG_01003 1e-45
KKOJADAG_01004 6.6e-190 D nuclear chromosome segregation
KKOJADAG_01005 5.8e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KKOJADAG_01006 4.6e-94 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KKOJADAG_01007 2.2e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KKOJADAG_01008 1.3e-85 folT S ECF transporter, substrate-specific component
KKOJADAG_01009 4.9e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
KKOJADAG_01010 2.8e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KKOJADAG_01011 4.4e-58 yabA L Involved in initiation control of chromosome replication
KKOJADAG_01012 1e-151 holB 2.7.7.7 L DNA polymerase III
KKOJADAG_01013 5e-51 yaaQ S Cyclic-di-AMP receptor
KKOJADAG_01014 1.2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KKOJADAG_01015 9e-26 S Protein of unknown function (DUF2508)
KKOJADAG_01016 6.9e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KKOJADAG_01017 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KKOJADAG_01018 3e-310 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KKOJADAG_01019 1e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KKOJADAG_01020 1e-40 S Protein conserved in bacteria
KKOJADAG_01021 3.3e-147
KKOJADAG_01022 3.9e-21
KKOJADAG_01023 2.3e-113 rsmC 2.1.1.172 J Methyltransferase
KKOJADAG_01024 2.7e-32
KKOJADAG_01025 3.6e-128 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
KKOJADAG_01026 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KKOJADAG_01027 4.2e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KKOJADAG_01028 1.5e-146 aatB ET ABC transporter substrate-binding protein
KKOJADAG_01029 1.5e-115 glnQ 3.6.3.21 E ABC transporter
KKOJADAG_01030 7.9e-109 glnP P ABC transporter permease
KKOJADAG_01031 2.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KKOJADAG_01032 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KKOJADAG_01033 9.8e-100 nusG K Participates in transcription elongation, termination and antitermination
KKOJADAG_01034 3.4e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KKOJADAG_01035 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KKOJADAG_01036 2.8e-188 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KKOJADAG_01037 1.3e-227 G Major Facilitator Superfamily
KKOJADAG_01038 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KKOJADAG_01039 1.5e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KKOJADAG_01040 1.7e-34
KKOJADAG_01041 1e-88 yvrI K sigma factor activity
KKOJADAG_01042 6e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KKOJADAG_01043 1.3e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KKOJADAG_01044 3.3e-269 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KKOJADAG_01045 2.2e-287 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KKOJADAG_01046 4.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KKOJADAG_01047 7.3e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KKOJADAG_01048 2.4e-187 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KKOJADAG_01049 8.4e-262 pepC 3.4.22.40 E Peptidase C1-like family
KKOJADAG_01050 1.3e-195 nss M transferase activity, transferring glycosyl groups
KKOJADAG_01051 7.4e-166 cpsJ S glycosyl transferase family 2
KKOJADAG_01052 3.6e-25 UW Tetratricopeptide repeat
KKOJADAG_01053 3.5e-310 S Bacterial membrane protein, YfhO
KKOJADAG_01054 0.0 aha1 P E1-E2 ATPase
KKOJADAG_01055 3.2e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
KKOJADAG_01056 4.9e-241 yjjP S Putative threonine/serine exporter
KKOJADAG_01057 6.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KKOJADAG_01058 2.3e-262 frdC 1.3.5.4 C FAD binding domain
KKOJADAG_01059 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KKOJADAG_01060 9.6e-68 metI P ABC transporter permease
KKOJADAG_01061 2.6e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KKOJADAG_01062 4.6e-157 metQ1 P Belongs to the nlpA lipoprotein family
KKOJADAG_01063 3.2e-55 L nuclease
KKOJADAG_01064 2.6e-139 F DNA/RNA non-specific endonuclease
KKOJADAG_01065 2.3e-48 K Helix-turn-helix domain
KKOJADAG_01066 9.8e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KKOJADAG_01067 2.6e-39 G PTS system fructose IIA component
KKOJADAG_01068 3.8e-124 G PTS system mannose/fructose/sorbose family IID component
KKOJADAG_01069 2.4e-126 agaC G PTS system sorbose-specific iic component
KKOJADAG_01070 2.2e-71 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
KKOJADAG_01071 5.1e-72 K UTRA domain
KKOJADAG_01072 3.6e-134 S PAS domain
KKOJADAG_01073 6.6e-107 3.2.2.20 K acetyltransferase
KKOJADAG_01074 8.7e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KKOJADAG_01075 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KKOJADAG_01076 5.5e-28 secG U Preprotein translocase
KKOJADAG_01077 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KKOJADAG_01078 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KKOJADAG_01079 3.5e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KKOJADAG_01080 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KKOJADAG_01081 1.4e-187 cggR K Putative sugar-binding domain
KKOJADAG_01083 2.4e-278 ycaM E amino acid
KKOJADAG_01084 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KKOJADAG_01085 6.2e-171 whiA K May be required for sporulation
KKOJADAG_01086 5.8e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KKOJADAG_01087 1.6e-160 rapZ S Displays ATPase and GTPase activities
KKOJADAG_01088 8.1e-91 S Short repeat of unknown function (DUF308)
KKOJADAG_01089 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KKOJADAG_01090 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KKOJADAG_01091 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KKOJADAG_01092 4.7e-161 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KKOJADAG_01093 1.1e-254 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KKOJADAG_01094 3.9e-207 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KKOJADAG_01095 0.0 lacZ 3.2.1.23 G -beta-galactosidase
KKOJADAG_01096 0.0 lacS G Transporter
KKOJADAG_01097 3.5e-188 lacR K Transcriptional regulator
KKOJADAG_01098 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KKOJADAG_01099 2e-185 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KKOJADAG_01100 4.8e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KKOJADAG_01101 9e-18 rnhA 3.1.26.4 L Ribonuclease HI
KKOJADAG_01103 6.1e-39 D nuclear chromosome segregation
KKOJADAG_01104 7.1e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KKOJADAG_01105 3.3e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KKOJADAG_01106 1.2e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KKOJADAG_01107 4.7e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KKOJADAG_01108 7.6e-24
KKOJADAG_01109 3.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KKOJADAG_01110 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KKOJADAG_01111 1.3e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KKOJADAG_01112 9.7e-126 comFC S Competence protein
KKOJADAG_01113 1.5e-225 comFA L Helicase C-terminal domain protein
KKOJADAG_01114 4.3e-118 yvyE 3.4.13.9 S YigZ family
KKOJADAG_01115 1.6e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
KKOJADAG_01116 6.9e-194 rny S Endoribonuclease that initiates mRNA decay
KKOJADAG_01117 3.5e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KKOJADAG_01118 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KKOJADAG_01119 9.8e-125 ymfM S Helix-turn-helix domain
KKOJADAG_01120 3.7e-131 IQ Enoyl-(Acyl carrier protein) reductase
KKOJADAG_01121 2.7e-230 S Peptidase M16
KKOJADAG_01122 3.5e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
KKOJADAG_01123 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KKOJADAG_01124 1.7e-75 WQ51_03320 S Protein of unknown function (DUF1149)
KKOJADAG_01125 4.6e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KKOJADAG_01126 7.2e-209 yubA S AI-2E family transporter
KKOJADAG_01127 4.9e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KKOJADAG_01128 2.2e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KKOJADAG_01129 5.4e-200 S Sterol carrier protein domain
KKOJADAG_01130 5.5e-166 arbZ I Acyltransferase
KKOJADAG_01131 8.8e-116 ywnB S NAD(P)H-binding
KKOJADAG_01132 4.7e-143 ropB K Helix-turn-helix domain
KKOJADAG_01133 9.4e-200 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
KKOJADAG_01134 8.5e-173 yxaM EGP Major Facilitator Superfamily
KKOJADAG_01135 9.3e-132 S Protein of unknown function (DUF975)
KKOJADAG_01136 1.5e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KKOJADAG_01137 1.6e-154 yitS S EDD domain protein, DegV family
KKOJADAG_01138 3.5e-17
KKOJADAG_01139 2.7e-291 V ABC-type multidrug transport system, ATPase and permease components
KKOJADAG_01140 3.7e-140 ropB K Helix-turn-helix domain
KKOJADAG_01141 0.0 tetP J elongation factor G
KKOJADAG_01142 7.3e-242 clcA P chloride
KKOJADAG_01143 0.0 pepO 3.4.24.71 O Peptidase family M13
KKOJADAG_01144 2.7e-114 ropB K Helix-turn-helix XRE-family like proteins
KKOJADAG_01145 7.5e-194 L COG2826 Transposase and inactivated derivatives, IS30 family
KKOJADAG_01146 2.3e-165 P CorA-like Mg2+ transporter protein
KKOJADAG_01148 4.2e-40 S Transglycosylase associated protein
KKOJADAG_01149 5.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
KKOJADAG_01150 0.0 L Helicase C-terminal domain protein
KKOJADAG_01151 7.7e-139 S Alpha beta hydrolase
KKOJADAG_01152 5.1e-07
KKOJADAG_01153 1.2e-29
KKOJADAG_01155 7.2e-16
KKOJADAG_01156 2.4e-26
KKOJADAG_01157 1.9e-168 K AI-2E family transporter
KKOJADAG_01158 2.9e-254 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
KKOJADAG_01159 3.1e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KKOJADAG_01160 1.5e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
KKOJADAG_01161 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KKOJADAG_01162 0.0 S domain, Protein
KKOJADAG_01163 2.4e-43 UW LPXTG-motif cell wall anchor domain protein
KKOJADAG_01164 6.2e-307 gadC E Contains amino acid permease domain
KKOJADAG_01165 1.3e-213 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
KKOJADAG_01166 5.1e-292 asp1 S Accessory Sec system protein Asp1
KKOJADAG_01167 6.2e-301 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
KKOJADAG_01168 6.7e-156 asp3 S Accessory Sec secretory system ASP3
KKOJADAG_01169 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KKOJADAG_01170 1.2e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KKOJADAG_01171 7.7e-260 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KKOJADAG_01172 2.3e-116 3.6.1.27 I Acid phosphatase homologues
KKOJADAG_01173 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KKOJADAG_01174 1.2e-299 ytgP S Polysaccharide biosynthesis protein
KKOJADAG_01175 1.5e-216 MA20_36090 S Protein of unknown function (DUF2974)
KKOJADAG_01176 4e-136
KKOJADAG_01177 8.7e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KKOJADAG_01178 4e-170 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KKOJADAG_01179 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KKOJADAG_01180 1.9e-172 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KKOJADAG_01181 5.1e-45
KKOJADAG_01182 0.0 K Sigma-54 interaction domain
KKOJADAG_01183 3.2e-55 2.7.1.191 G PTS system fructose IIA component
KKOJADAG_01184 7e-81 ptsB 2.7.1.191 G PTS system sorbose subfamily IIB component
KKOJADAG_01185 3.1e-137 ptsC G PTS system sorbose-specific iic component
KKOJADAG_01186 4.5e-149 ptsD G PTS system mannose/fructose/sorbose family IID component
KKOJADAG_01187 2.6e-113 mgtC S MgtC family
KKOJADAG_01188 2.8e-134 K Sigma-54 factor, core binding domain
KKOJADAG_01190 1.5e-92 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KKOJADAG_01191 1.5e-126 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
KKOJADAG_01192 4.9e-111 ylbE GM NAD(P)H-binding
KKOJADAG_01193 8.5e-81 yebR 1.8.4.14 T GAF domain-containing protein
KKOJADAG_01194 1.9e-220 yfeO P Voltage gated chloride channel
KKOJADAG_01195 1.8e-192 S Bacteriocin helveticin-J
KKOJADAG_01196 8.5e-99 tag 3.2.2.20 L glycosylase
KKOJADAG_01197 1.5e-161 mleP3 S Membrane transport protein
KKOJADAG_01198 9.3e-136 S CAAX amino terminal protease
KKOJADAG_01199 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KKOJADAG_01200 3.2e-254 emrY EGP Major facilitator Superfamily
KKOJADAG_01201 3.6e-258 emrY EGP Major facilitator Superfamily
KKOJADAG_01202 3.1e-69
KKOJADAG_01203 2e-26 S Protein of unknown function (DUF2929)
KKOJADAG_01204 0.0 dnaE 2.7.7.7 L DNA polymerase
KKOJADAG_01205 3e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KKOJADAG_01206 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KKOJADAG_01207 1.2e-166 cvfB S S1 domain
KKOJADAG_01208 2.2e-165 xerD D recombinase XerD
KKOJADAG_01209 1.8e-62 ribT K acetyltransferase
KKOJADAG_01210 9.1e-133 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KKOJADAG_01211 3.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KKOJADAG_01212 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KKOJADAG_01213 3.9e-62 M Lysin motif
KKOJADAG_01214 2.4e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KKOJADAG_01215 2.1e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KKOJADAG_01216 6e-219 rpsA 1.17.7.4 J Ribosomal protein S1
KKOJADAG_01217 3.4e-244 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KKOJADAG_01218 6.7e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KKOJADAG_01219 6.5e-232 S Tetratricopeptide repeat protein
KKOJADAG_01220 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KKOJADAG_01221 2.1e-214 hsdM 2.1.1.72 V type I restriction-modification system
KKOJADAG_01224 3.2e-20 S Bacteriocin class II with double-glycine leader peptide
KKOJADAG_01225 4.9e-105 M Transport protein ComB
KKOJADAG_01226 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KKOJADAG_01227 1.2e-143 K LytTr DNA-binding domain
KKOJADAG_01228 8.6e-223 L Putative transposase DNA-binding domain
KKOJADAG_01230 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KKOJADAG_01231 1.8e-295 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KKOJADAG_01232 2.7e-14 ropB K Helix-turn-helix domain
KKOJADAG_01233 8.1e-114
KKOJADAG_01235 0.0 nisT V ABC transporter
KKOJADAG_01236 9.5e-16
KKOJADAG_01237 2.2e-36
KKOJADAG_01238 4.6e-76 EGP Major facilitator Superfamily
KKOJADAG_01239 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KKOJADAG_01240 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KKOJADAG_01241 9.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KKOJADAG_01242 1.3e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KKOJADAG_01243 1.2e-39 yajC U Preprotein translocase
KKOJADAG_01244 2.2e-284 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KKOJADAG_01245 1.2e-208 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KKOJADAG_01246 1.9e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KKOJADAG_01247 1.8e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KKOJADAG_01248 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KKOJADAG_01249 2.6e-42 yrzL S Belongs to the UPF0297 family
KKOJADAG_01250 8.8e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KKOJADAG_01251 4.2e-39 yrzB S Belongs to the UPF0473 family
KKOJADAG_01252 3.9e-93 cvpA S Colicin V production protein
KKOJADAG_01253 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KKOJADAG_01254 1.1e-52 trxA O Belongs to the thioredoxin family
KKOJADAG_01255 3.2e-68 yslB S Protein of unknown function (DUF2507)
KKOJADAG_01256 1.7e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KKOJADAG_01257 1e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KKOJADAG_01258 0.0 UW LPXTG-motif cell wall anchor domain protein
KKOJADAG_01259 2.9e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KKOJADAG_01260 6e-139 ykuT M mechanosensitive ion channel
KKOJADAG_01261 1.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KKOJADAG_01262 9.6e-50
KKOJADAG_01263 3.8e-212 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KKOJADAG_01264 9.8e-175 ccpA K catabolite control protein A
KKOJADAG_01265 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
KKOJADAG_01266 9e-275 pepV 3.5.1.18 E dipeptidase PepV
KKOJADAG_01267 6.8e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KKOJADAG_01268 1.3e-54
KKOJADAG_01269 1e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KKOJADAG_01270 9.3e-95 yutD S Protein of unknown function (DUF1027)
KKOJADAG_01271 1.2e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KKOJADAG_01272 1.5e-104 S Protein of unknown function (DUF1461)
KKOJADAG_01273 2.7e-117 dedA S SNARE-like domain protein
KKOJADAG_01274 1.4e-178 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KKOJADAG_01275 4.2e-62 yugI 5.3.1.9 J general stress protein
KKOJADAG_01276 3.9e-133 S Putative ABC-transporter type IV
KKOJADAG_01277 1.5e-60 psiE S Phosphate-starvation-inducible E
KKOJADAG_01278 2.9e-93 K acetyltransferase
KKOJADAG_01280 2.3e-164 yvgN C Aldo keto reductase
KKOJADAG_01281 2.3e-248 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KKOJADAG_01282 1.4e-69 S Uncharacterized protein conserved in bacteria (DUF2263)
KKOJADAG_01283 3.7e-174 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KKOJADAG_01284 0.0 lhr L DEAD DEAH box helicase
KKOJADAG_01285 3.2e-253 P P-loop Domain of unknown function (DUF2791)
KKOJADAG_01286 0.0 S TerB-C domain
KKOJADAG_01287 4.1e-37 4.1.1.44 S decarboxylase
KKOJADAG_01288 9.6e-81 4.1.1.44 S decarboxylase
KKOJADAG_01289 1.5e-71
KKOJADAG_01290 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KKOJADAG_01291 1.2e-244 cycA E Amino acid permease
KKOJADAG_01292 1.2e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KKOJADAG_01293 1.4e-57 asp S Asp23 family, cell envelope-related function
KKOJADAG_01294 3.6e-307 yloV S DAK2 domain fusion protein YloV
KKOJADAG_01295 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KKOJADAG_01296 6e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KKOJADAG_01297 4.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KKOJADAG_01298 9e-192 oppD P Belongs to the ABC transporter superfamily
KKOJADAG_01299 9.9e-180 oppF P Belongs to the ABC transporter superfamily
KKOJADAG_01300 5.6e-175 oppB P ABC transporter permease
KKOJADAG_01301 1.1e-161 oppC P Binding-protein-dependent transport system inner membrane component
KKOJADAG_01302 0.0 oppA E ABC transporter substrate-binding protein
KKOJADAG_01303 0.0 oppA E ABC transporter substrate-binding protein
KKOJADAG_01304 2.7e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KKOJADAG_01305 0.0 smc D Required for chromosome condensation and partitioning
KKOJADAG_01306 2.6e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KKOJADAG_01307 3.6e-287 pipD E Dipeptidase
KKOJADAG_01308 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KKOJADAG_01309 3.8e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KKOJADAG_01310 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KKOJADAG_01311 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KKOJADAG_01312 5e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KKOJADAG_01313 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KKOJADAG_01314 2.1e-117 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KKOJADAG_01315 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KKOJADAG_01316 2.1e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
KKOJADAG_01317 1e-113 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KKOJADAG_01318 2.5e-34 ynzC S UPF0291 protein
KKOJADAG_01319 1.9e-30 yneF S Uncharacterised protein family (UPF0154)
KKOJADAG_01320 0.0 mdlA V ABC transporter
KKOJADAG_01321 1.4e-283 mdlB V ABC transporter
KKOJADAG_01322 3e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KKOJADAG_01323 2.6e-117 plsC 2.3.1.51 I Acyltransferase
KKOJADAG_01324 1.8e-195 yabB 2.1.1.223 L Methyltransferase small domain
KKOJADAG_01325 5.8e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
KKOJADAG_01326 9.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KKOJADAG_01327 1.8e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KKOJADAG_01328 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KKOJADAG_01329 1.2e-134 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KKOJADAG_01330 1.5e-138 cdsA 2.7.7.41 S Belongs to the CDS family
KKOJADAG_01331 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KKOJADAG_01332 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KKOJADAG_01333 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KKOJADAG_01334 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
KKOJADAG_01335 3.2e-220 nusA K Participates in both transcription termination and antitermination
KKOJADAG_01336 1.5e-46 ylxR K Protein of unknown function (DUF448)
KKOJADAG_01337 7.1e-47 rplGA J ribosomal protein
KKOJADAG_01338 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KKOJADAG_01339 3.5e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KKOJADAG_01340 2.3e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KKOJADAG_01341 1.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KKOJADAG_01342 1.6e-282 lsa S ABC transporter
KKOJADAG_01343 9.8e-96 S GyrI-like small molecule binding domain
KKOJADAG_01344 1.7e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KKOJADAG_01345 5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KKOJADAG_01346 0.0 dnaK O Heat shock 70 kDa protein
KKOJADAG_01347 5.7e-174 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KKOJADAG_01348 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KKOJADAG_01349 3.5e-123 srtA 3.4.22.70 M sortase family
KKOJADAG_01350 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KKOJADAG_01351 4.8e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KKOJADAG_01352 2e-275 yjeM E Amino Acid
KKOJADAG_01353 2e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KKOJADAG_01354 1.2e-185 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KKOJADAG_01355 9e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KKOJADAG_01356 1.7e-251 G Major Facilitator
KKOJADAG_01357 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
KKOJADAG_01358 1.9e-158 lysR5 K LysR substrate binding domain
KKOJADAG_01360 1.3e-102 3.6.1.27 I Acid phosphatase homologues
KKOJADAG_01361 6.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KKOJADAG_01362 3.7e-18 S Sugar efflux transporter for intercellular exchange
KKOJADAG_01363 5.7e-305 ybiT S ABC transporter, ATP-binding protein
KKOJADAG_01364 5.3e-68 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KKOJADAG_01365 9.7e-172 prmA J Ribosomal protein L11 methyltransferase
KKOJADAG_01366 2.4e-65
KKOJADAG_01367 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KKOJADAG_01368 1.3e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KKOJADAG_01369 6.2e-246 hisS 6.1.1.21 J histidyl-tRNA synthetase
KKOJADAG_01370 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KKOJADAG_01371 0.0 uup S ABC transporter, ATP-binding protein
KKOJADAG_01372 4.4e-244 G Bacterial extracellular solute-binding protein
KKOJADAG_01373 4e-120 liaI S membrane
KKOJADAG_01374 2.7e-79 XK27_02470 K LytTr DNA-binding domain
KKOJADAG_01375 6.7e-50 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
KKOJADAG_01376 5.2e-104 yvdD 3.2.2.10 S Belongs to the LOG family
KKOJADAG_01377 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KKOJADAG_01378 3.8e-246 yagE E amino acid
KKOJADAG_01379 1.8e-116 GM NmrA-like family
KKOJADAG_01380 3.6e-151 xerD L Phage integrase, N-terminal SAM-like domain
KKOJADAG_01381 1.6e-90 dedA 3.1.3.1 S SNARE associated Golgi protein
KKOJADAG_01382 7e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
KKOJADAG_01383 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KKOJADAG_01384 2.7e-241 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KKOJADAG_01385 0.0 oatA I Acyltransferase
KKOJADAG_01386 3e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KKOJADAG_01387 3.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KKOJADAG_01388 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
KKOJADAG_01389 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KKOJADAG_01390 1.6e-304 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KKOJADAG_01391 1.8e-223 patA 2.6.1.1 E Aminotransferase
KKOJADAG_01392 3.1e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KKOJADAG_01393 3.4e-135 E GDSL-like Lipase/Acylhydrolase family
KKOJADAG_01394 1.6e-07
KKOJADAG_01395 1.8e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KKOJADAG_01396 4.5e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KKOJADAG_01397 8.7e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KKOJADAG_01398 8.8e-151 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KKOJADAG_01399 1.1e-50 S Iron-sulfur cluster assembly protein
KKOJADAG_01400 1.7e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KKOJADAG_01401 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KKOJADAG_01402 2.9e-33 yqeY S YqeY-like protein
KKOJADAG_01403 6.8e-173 phoH T phosphate starvation-inducible protein PhoH
KKOJADAG_01404 2.6e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KKOJADAG_01405 7.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KKOJADAG_01406 1.4e-136 recO L Involved in DNA repair and RecF pathway recombination
KKOJADAG_01407 2.7e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KKOJADAG_01408 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KKOJADAG_01409 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KKOJADAG_01410 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KKOJADAG_01411 4.7e-120
KKOJADAG_01412 5.4e-92
KKOJADAG_01415 1.4e-185 M domain protein
KKOJADAG_01416 1.8e-164 S DNA/RNA non-specific endonuclease
KKOJADAG_01417 0.0 UW LPXTG-motif cell wall anchor domain protein
KKOJADAG_01418 4.4e-185 S AAA domain
KKOJADAG_01419 3.1e-124 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KKOJADAG_01420 9.9e-12
KKOJADAG_01421 7e-40
KKOJADAG_01422 7.7e-155 czcD P cation diffusion facilitator family transporter
KKOJADAG_01423 4.2e-50 K Transcriptional regulator, ArsR family
KKOJADAG_01424 1.1e-129 pgm3 G Belongs to the phosphoglycerate mutase family
KKOJADAG_01425 1.1e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KKOJADAG_01426 1.9e-150 1.6.5.2 GM NmrA-like family
KKOJADAG_01427 1.6e-68 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
KKOJADAG_01428 7e-292 V ABC-type multidrug transport system, ATPase and permease components
KKOJADAG_01429 5.6e-229 P ABC transporter
KKOJADAG_01431 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KKOJADAG_01432 5e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KKOJADAG_01433 5.1e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KKOJADAG_01434 7.4e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KKOJADAG_01435 1.7e-162 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KKOJADAG_01436 1.5e-155 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KKOJADAG_01437 3.7e-61 rplQ J Ribosomal protein L17
KKOJADAG_01438 9.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKOJADAG_01439 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KKOJADAG_01440 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KKOJADAG_01441 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KKOJADAG_01442 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KKOJADAG_01443 4.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KKOJADAG_01444 4.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KKOJADAG_01445 1.3e-70 rplO J Binds to the 23S rRNA
KKOJADAG_01446 1.4e-23 rpmD J Ribosomal protein L30
KKOJADAG_01447 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KKOJADAG_01448 1.5e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KKOJADAG_01449 8.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KKOJADAG_01450 2.1e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KKOJADAG_01451 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KKOJADAG_01452 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KKOJADAG_01453 1.1e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KKOJADAG_01454 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KKOJADAG_01455 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KKOJADAG_01456 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KKOJADAG_01457 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KKOJADAG_01458 7.2e-121 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KKOJADAG_01459 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KKOJADAG_01460 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KKOJADAG_01461 1.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KKOJADAG_01462 1.7e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KKOJADAG_01463 1e-105 rplD J Forms part of the polypeptide exit tunnel
KKOJADAG_01464 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KKOJADAG_01465 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KKOJADAG_01466 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KKOJADAG_01467 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KKOJADAG_01468 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KKOJADAG_01469 1.3e-106 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KKOJADAG_01470 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKOJADAG_01471 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KKOJADAG_01472 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KKOJADAG_01474 1.6e-08
KKOJADAG_01475 2.1e-301 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KKOJADAG_01476 1.5e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KKOJADAG_01477 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KKOJADAG_01478 0.0 S membrane
KKOJADAG_01479 0.0 S membrane
KKOJADAG_01480 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KKOJADAG_01481 1.1e-242 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KKOJADAG_01482 4.9e-60 yabR J S1 RNA binding domain
KKOJADAG_01483 4e-60 divIC D Septum formation initiator
KKOJADAG_01484 5.4e-34 yabO J S4 domain protein
KKOJADAG_01485 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KKOJADAG_01486 1.9e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KKOJADAG_01487 3.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KKOJADAG_01488 2.3e-122 S (CBS) domain
KKOJADAG_01489 2.5e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KKOJADAG_01490 5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KKOJADAG_01491 1.9e-267 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KKOJADAG_01492 7.2e-261 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KKOJADAG_01493 8e-41 rpmE2 J Ribosomal protein L31
KKOJADAG_01494 4.6e-299 ybeC E amino acid
KKOJADAG_01495 1.7e-134 XK27_08845 S ABC transporter, ATP-binding protein
KKOJADAG_01496 6.4e-141 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KKOJADAG_01497 1.5e-178 ABC-SBP S ABC transporter
KKOJADAG_01498 4.7e-227 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KKOJADAG_01499 2.4e-283 pipD E Dipeptidase
KKOJADAG_01500 2.7e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KKOJADAG_01501 9.8e-77 XK27_02070 S Nitroreductase family
KKOJADAG_01502 1.1e-31 hxlR K Transcriptional regulator, HxlR family
KKOJADAG_01503 2.1e-79
KKOJADAG_01504 3.2e-66 S Putative adhesin
KKOJADAG_01505 4.6e-39
KKOJADAG_01506 1.2e-190 yfdV S Membrane transport protein
KKOJADAG_01507 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KKOJADAG_01508 4.1e-264 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KKOJADAG_01509 6.8e-95
KKOJADAG_01510 5.8e-56 K Transcriptional regulator
KKOJADAG_01511 4.3e-86 XK27_09675 K Acetyltransferase (GNAT) domain
KKOJADAG_01512 1.4e-63 S Protein of unknown function (DUF3021)
KKOJADAG_01513 2.2e-73 K LytTr DNA-binding domain
KKOJADAG_01514 1.4e-145 cylB V ABC-2 type transporter
KKOJADAG_01515 1.7e-151 cylA V ABC transporter
KKOJADAG_01516 2.5e-259 qacA EGP Major facilitator Superfamily
KKOJADAG_01517 4.8e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KKOJADAG_01521 1.5e-94 2.7.1.202 GKT Mga helix-turn-helix domain
KKOJADAG_01522 9.5e-235 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KKOJADAG_01523 5.8e-26 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
KKOJADAG_01524 2.4e-191 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KKOJADAG_01525 3.2e-39 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
KKOJADAG_01526 2e-12 yttA 2.7.13.3 S Pfam Transposase IS66
KKOJADAG_01527 4e-86
KKOJADAG_01528 1.5e-124
KKOJADAG_01530 5.9e-188 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KKOJADAG_01531 6.7e-118 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KKOJADAG_01532 1.1e-164 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KKOJADAG_01533 5.4e-208 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KKOJADAG_01534 9e-220 KQ helix_turn_helix, mercury resistance
KKOJADAG_01535 1.3e-11
KKOJADAG_01536 6.3e-31
KKOJADAG_01538 1.6e-21 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KKOJADAG_01539 6.9e-49 S PFAM Archaeal ATPase
KKOJADAG_01540 3e-34 S PFAM Archaeal ATPase
KKOJADAG_01541 1.3e-70 S PFAM Archaeal ATPase
KKOJADAG_01542 0.0 uvrA3 L excinuclease ABC, A subunit
KKOJADAG_01544 1.5e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KKOJADAG_01545 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KKOJADAG_01546 3.3e-76 yphH S Cupin domain
KKOJADAG_01547 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KKOJADAG_01548 2.6e-71 K helix_turn_helix multiple antibiotic resistance protein
KKOJADAG_01549 0.0 lmrA 3.6.3.44 V ABC transporter
KKOJADAG_01550 6.5e-156 C Aldo keto reductase
KKOJADAG_01551 1.4e-234 yrvN L AAA C-terminal domain
KKOJADAG_01552 4.3e-169 4.1.1.45 S Amidohydrolase
KKOJADAG_01553 3.7e-32
KKOJADAG_01554 4.8e-107 ybhL S Belongs to the BI1 family
KKOJADAG_01555 2.1e-165 akr5f 1.1.1.346 S reductase
KKOJADAG_01556 3.5e-106 lacA 2.3.1.79 S Transferase hexapeptide repeat
KKOJADAG_01557 7.5e-115 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KKOJADAG_01558 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KKOJADAG_01559 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KKOJADAG_01560 2.4e-178 K Transcriptional regulator
KKOJADAG_01561 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
KKOJADAG_01562 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KKOJADAG_01563 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KKOJADAG_01564 1.6e-123 yoaK S Protein of unknown function (DUF1275)
KKOJADAG_01565 8.3e-204 xerS L Belongs to the 'phage' integrase family
KKOJADAG_01566 1.4e-153 K Transcriptional regulator
KKOJADAG_01567 1e-151
KKOJADAG_01568 1e-162 degV S EDD domain protein, DegV family
KKOJADAG_01569 1.4e-63
KKOJADAG_01570 0.0 FbpA K Fibronectin-binding protein
KKOJADAG_01571 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
KKOJADAG_01572 1.3e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KKOJADAG_01573 2.1e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KKOJADAG_01574 2.9e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KKOJADAG_01575 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KKOJADAG_01576 3.2e-56
KKOJADAG_01577 2e-174 degV S DegV family
KKOJADAG_01578 7.6e-224 I transferase activity, transferring acyl groups other than amino-acyl groups
KKOJADAG_01579 6.1e-243 cpdA S Calcineurin-like phosphoesterase
KKOJADAG_01580 7.6e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KKOJADAG_01581 4.5e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KKOJADAG_01582 2.7e-105 ypsA S Belongs to the UPF0398 family
KKOJADAG_01583 1.3e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KKOJADAG_01584 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KKOJADAG_01585 1.1e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KKOJADAG_01586 3.7e-114 dnaD L DnaD domain protein
KKOJADAG_01587 6.4e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KKOJADAG_01588 6.3e-90 ypmB S Protein conserved in bacteria
KKOJADAG_01589 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KKOJADAG_01590 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KKOJADAG_01591 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KKOJADAG_01592 2e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
KKOJADAG_01593 1.3e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KKOJADAG_01594 2.7e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KKOJADAG_01595 8.8e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KKOJADAG_01596 1.6e-280 V ABC-type multidrug transport system, ATPase and permease components
KKOJADAG_01597 5e-290 V ABC-type multidrug transport system, ATPase and permease components
KKOJADAG_01598 5.5e-212 G Transmembrane secretion effector
KKOJADAG_01599 3.4e-157 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
KKOJADAG_01600 2.1e-160 rbsU U ribose uptake protein RbsU
KKOJADAG_01601 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KKOJADAG_01602 3.5e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KKOJADAG_01603 2.8e-84 6.3.3.2 S ASCH
KKOJADAG_01604 7.8e-151 2.4.2.3 F Phosphorylase superfamily
KKOJADAG_01605 1.5e-149 2.4.2.3 F Phosphorylase superfamily
KKOJADAG_01606 2.2e-84 3.6.1.55 F NUDIX domain
KKOJADAG_01607 8.7e-153 2.7.1.89 M Phosphotransferase enzyme family
KKOJADAG_01608 6.9e-92 S AAA domain
KKOJADAG_01609 1.9e-81
KKOJADAG_01610 5.5e-113
KKOJADAG_01611 3.2e-141 S Alpha/beta hydrolase family
KKOJADAG_01612 4.9e-116 XK27_07525 3.6.1.55 F NUDIX domain
KKOJADAG_01613 4.4e-91 2.3.1.57 K Acetyltransferase (GNAT) family
KKOJADAG_01614 6.4e-93 rimL J Acetyltransferase (GNAT) domain
KKOJADAG_01615 2.4e-141 aroD S Serine hydrolase (FSH1)
KKOJADAG_01616 1.1e-245 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KKOJADAG_01617 5e-42
KKOJADAG_01618 3e-118 3.1.3.48 T Tyrosine phosphatase family
KKOJADAG_01619 7.7e-61
KKOJADAG_01620 3.4e-46 S MazG-like family
KKOJADAG_01621 6.3e-84 FG HIT domain
KKOJADAG_01622 1.3e-76 K Acetyltransferase (GNAT) domain
KKOJADAG_01623 2.1e-55
KKOJADAG_01624 5.5e-53
KKOJADAG_01625 1.3e-219 V ABC transporter transmembrane region
KKOJADAG_01626 2.9e-48 V ABC transporter transmembrane region
KKOJADAG_01627 1.3e-84 C nitroreductase
KKOJADAG_01628 3.5e-211 yhjX P Major Facilitator Superfamily
KKOJADAG_01629 2e-244 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KKOJADAG_01630 3e-295 V ABC-type multidrug transport system, ATPase and permease components
KKOJADAG_01631 9.8e-185 P ABC transporter
KKOJADAG_01632 5.8e-77 qmcA O prohibitin homologues
KKOJADAG_01633 3.1e-47 qmcA O prohibitin homologues
KKOJADAG_01634 1.4e-08 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
KKOJADAG_01635 2.4e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KKOJADAG_01636 6.4e-90 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
KKOJADAG_01637 2.8e-09 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
KKOJADAG_01638 4.3e-73 S SnoaL-like domain
KKOJADAG_01639 2.9e-170 C Oxidoreductase
KKOJADAG_01640 1.8e-116 drgA C nitroreductase
KKOJADAG_01641 2.3e-308 2.7.7.7 S Domain of unknown function (DUF5060)
KKOJADAG_01642 1.8e-170 uhpT EGP Major facilitator Superfamily
KKOJADAG_01643 2.7e-169 rbsR K helix_turn _helix lactose operon repressor
KKOJADAG_01644 0.0 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKOJADAG_01645 1.7e-151 licT K CAT RNA binding domain
KKOJADAG_01646 1.4e-261 G Protein of unknown function (DUF4038)
KKOJADAG_01647 1.9e-291 G isomerase
KKOJADAG_01648 2.2e-185 purR13 K Bacterial regulatory proteins, lacI family
KKOJADAG_01649 8.8e-153 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
KKOJADAG_01650 3.8e-176 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
KKOJADAG_01651 2.4e-262 glpK_1 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KKOJADAG_01652 0.0 pepO 3.4.24.71 O Peptidase family M13
KKOJADAG_01653 2.3e-109
KKOJADAG_01654 3.3e-106 S AAA domain, putative AbiEii toxin, Type IV TA system
KKOJADAG_01655 1.6e-163 htpX O Peptidase family M48
KKOJADAG_01657 6.8e-84
KKOJADAG_01658 3.7e-81 mutT 3.6.1.55 F NUDIX domain
KKOJADAG_01659 3.9e-39
KKOJADAG_01660 2.5e-68
KKOJADAG_01661 9.9e-67 S Domain of unknown function DUF1828
KKOJADAG_01662 3.4e-99 S Rib/alpha-like repeat
KKOJADAG_01665 1.1e-248 steT E amino acid
KKOJADAG_01666 1.6e-216 L Belongs to the 'phage' integrase family
KKOJADAG_01667 1.5e-31
KKOJADAG_01668 4.6e-108 repB EP Plasmid replication protein
KKOJADAG_01669 3.7e-83 repB EP Plasmid replication protein
KKOJADAG_01670 8.6e-93
KKOJADAG_01671 1.7e-131 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KKOJADAG_01672 4.6e-54
KKOJADAG_01673 1.4e-181
KKOJADAG_01674 9.2e-59 cadX K Bacterial regulatory protein, arsR family
KKOJADAG_01675 5.6e-96 cadD P Cadmium resistance transporter
KKOJADAG_01677 0.0
KKOJADAG_01678 2.2e-218 I Protein of unknown function (DUF2974)
KKOJADAG_01679 1.7e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KKOJADAG_01680 1.8e-243 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KKOJADAG_01681 4.8e-76 rplI J Binds to the 23S rRNA
KKOJADAG_01682 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KKOJADAG_01683 3.5e-158 corA P CorA-like Mg2+ transporter protein
KKOJADAG_01684 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KKOJADAG_01685 7.3e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KKOJADAG_01686 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
KKOJADAG_01687 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KKOJADAG_01688 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KKOJADAG_01689 1.2e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KKOJADAG_01690 1.6e-20 yaaA S S4 domain
KKOJADAG_01691 1.2e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KKOJADAG_01692 2.4e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KKOJADAG_01693 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KKOJADAG_01694 7.8e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KKOJADAG_01695 1.6e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KKOJADAG_01696 3.3e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KKOJADAG_01697 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KKOJADAG_01698 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KKOJADAG_01699 6e-271 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KKOJADAG_01700 3.5e-288 clcA P chloride
KKOJADAG_01701 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KKOJADAG_01702 1.1e-08 S RelB antitoxin
KKOJADAG_01703 2.6e-162 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KKOJADAG_01704 1.2e-210 pbuG S permease
KKOJADAG_01705 5.8e-287 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KKOJADAG_01706 5.1e-69 S Iron-sulphur cluster biosynthesis
KKOJADAG_01707 1e-229 EGP Sugar (and other) transporter
KKOJADAG_01708 1.4e-69 K Acetyltransferase (GNAT) domain
KKOJADAG_01709 8.5e-248 ynbB 4.4.1.1 P aluminum resistance
KKOJADAG_01710 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KKOJADAG_01711 7.3e-283 E Amino acid permease
KKOJADAG_01712 1.2e-158 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KKOJADAG_01713 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
KKOJADAG_01715 4e-16
KKOJADAG_01716 3.5e-82 2.3.1.128 K acetyltransferase
KKOJADAG_01717 7.9e-202 S PFAM Archaeal ATPase
KKOJADAG_01718 7.6e-146 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KKOJADAG_01719 5.1e-101 yagU S Protein of unknown function (DUF1440)
KKOJADAG_01720 4.4e-149 S hydrolase
KKOJADAG_01721 7.7e-157 K Transcriptional regulator
KKOJADAG_01722 4.3e-242 pyrP F Permease
KKOJADAG_01723 6e-132 lacR K DeoR C terminal sensor domain
KKOJADAG_01724 5.1e-72 lacA 5.3.1.26 G Ribose/Galactose Isomerase
KKOJADAG_01725 1.6e-105 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
KKOJADAG_01726 2.5e-14 lacT K CAT RNA binding domain
KKOJADAG_01727 3.4e-96 lacT K CAT RNA binding domain
KKOJADAG_01728 1.5e-53 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
KKOJADAG_01729 1.1e-298 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
KKOJADAG_01730 4e-278 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
KKOJADAG_01731 8.8e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
KKOJADAG_01732 2.8e-111 3.6.1.27 I Acid phosphatase homologues
KKOJADAG_01733 3.9e-283 E Phospholipase B
KKOJADAG_01734 8e-265 pepC 3.4.22.40 E Peptidase C1-like family
KKOJADAG_01735 2.8e-283 gadC E Contains amino acid permease domain
KKOJADAG_01736 6.3e-276 pipD E Peptidase family C69
KKOJADAG_01737 1.6e-265 pepC 3.4.22.40 E Peptidase C1-like family
KKOJADAG_01738 1.3e-309 gadC E Contains amino acid permease domain
KKOJADAG_01739 9.5e-155 E Amino acid permease
KKOJADAG_01740 8.8e-158 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
KKOJADAG_01741 1.7e-104 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
KKOJADAG_01742 1.2e-244 yagE E amino acid
KKOJADAG_01743 2.2e-213 mdtG EGP Major facilitator Superfamily
KKOJADAG_01744 8.6e-28
KKOJADAG_01745 6.7e-69 K helix_turn_helix multiple antibiotic resistance protein
KKOJADAG_01746 6.5e-78
KKOJADAG_01747 3.3e-208 pepA E M42 glutamyl aminopeptidase
KKOJADAG_01749 4.4e-115 ybbL S ABC transporter, ATP-binding protein
KKOJADAG_01750 2.8e-129 ybbM S Uncharacterised protein family (UPF0014)
KKOJADAG_01751 3.8e-211 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
KKOJADAG_01752 3.9e-82 lacA 3.2.1.23 G -beta-galactosidase
KKOJADAG_01753 8.7e-284 dtpT U amino acid peptide transporter
KKOJADAG_01754 1.6e-279 pipD E Peptidase family C69
KKOJADAG_01755 1.3e-216 naiP EGP Major facilitator Superfamily
KKOJADAG_01756 1.7e-154 S Alpha beta hydrolase
KKOJADAG_01757 8.7e-67 K Transcriptional regulator, MarR family
KKOJADAG_01758 8.5e-299 XK27_09600 V ABC transporter, ATP-binding protein
KKOJADAG_01759 0.0 V ABC transporter transmembrane region
KKOJADAG_01760 1.4e-147 glnH ET ABC transporter
KKOJADAG_01761 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KKOJADAG_01762 3.1e-150 glnH ET ABC transporter
KKOJADAG_01763 2.4e-110 gluC P ABC transporter permease
KKOJADAG_01764 5.7e-107 glnP P ABC transporter permease
KKOJADAG_01765 1.9e-65
KKOJADAG_01766 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
KKOJADAG_01767 2e-129 treR K UTRA
KKOJADAG_01768 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KKOJADAG_01769 6.4e-76 S Putative adhesin
KKOJADAG_01771 2.3e-113 udk 2.7.1.48 F Cytidine monophosphokinase
KKOJADAG_01773 9.2e-205 2.7.13.3 T GHKL domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)