ORF_ID e_value Gene_name EC_number CAZy COGs Description
HILOHAJA_00002 2e-237 mmr U Major Facilitator Superfamily
HILOHAJA_00003 1.5e-77 yffB K Transcriptional regulator
HILOHAJA_00004 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HILOHAJA_00005 4.3e-255 ywfO S COG1078 HD superfamily phosphohydrolases
HILOHAJA_00006 3.1e-36 ywzC S Belongs to the UPF0741 family
HILOHAJA_00007 1e-110 rsfA_1
HILOHAJA_00008 5.7e-158 ywfM EG EamA-like transporter family
HILOHAJA_00009 1.3e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HILOHAJA_00010 1.1e-156 cysL K Transcriptional regulator
HILOHAJA_00011 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HILOHAJA_00012 3.3e-146 ywfI C May function as heme-dependent peroxidase
HILOHAJA_00017 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
HILOHAJA_00018 3.2e-44
HILOHAJA_00019 2.4e-83 UW nuclease activity
HILOHAJA_00020 1.4e-48 M nucleic acid phosphodiester bond hydrolysis
HILOHAJA_00021 2.8e-33 K Helix-turn-helix XRE-family like proteins
HILOHAJA_00022 4.6e-42
HILOHAJA_00023 5.4e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HILOHAJA_00024 8.7e-30 cspL K Cold shock
HILOHAJA_00025 6.1e-79 carD K Transcription factor
HILOHAJA_00026 2.9e-138 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HILOHAJA_00027 1.7e-162 rhaS5 K AraC-like ligand binding domain
HILOHAJA_00028 4.1e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HILOHAJA_00029 6.9e-164 ydeE K AraC family transcriptional regulator
HILOHAJA_00030 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILOHAJA_00031 1.2e-217 ydeG EGP Major facilitator superfamily
HILOHAJA_00032 8e-45 ydeH
HILOHAJA_00033 7.8e-103 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HILOHAJA_00034 1.3e-103
HILOHAJA_00035 1.1e-31 S SNARE associated Golgi protein
HILOHAJA_00036 1.8e-14 ptsH G PTS HPr component phosphorylation site
HILOHAJA_00037 8.8e-85 K Transcriptional regulator C-terminal region
HILOHAJA_00038 1.8e-153 ydeK EG -transporter
HILOHAJA_00039 1.4e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILOHAJA_00040 7.1e-74 maoC I N-terminal half of MaoC dehydratase
HILOHAJA_00041 2.8e-105 ydeN S Serine hydrolase
HILOHAJA_00042 1.2e-55 K HxlR-like helix-turn-helix
HILOHAJA_00043 2.1e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HILOHAJA_00044 1.1e-191 ydeR EGP Major facilitator Superfamily
HILOHAJA_00045 2.1e-103 ydeS K Transcriptional regulator
HILOHAJA_00046 6.3e-57 arsR K transcriptional
HILOHAJA_00047 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HILOHAJA_00048 1.8e-147 ydfB J GNAT acetyltransferase
HILOHAJA_00049 8.5e-157 ydfC EG EamA-like transporter family
HILOHAJA_00050 6e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILOHAJA_00051 5e-116 ydfE S Flavin reductase like domain
HILOHAJA_00052 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HILOHAJA_00053 1.7e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HILOHAJA_00055 8.8e-175 ydfH 2.7.13.3 T Histidine kinase
HILOHAJA_00056 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILOHAJA_00057 0.0 ydfJ S drug exporters of the RND superfamily
HILOHAJA_00058 3.1e-175 S Alpha/beta hydrolase family
HILOHAJA_00059 8.5e-117 S Protein of unknown function (DUF554)
HILOHAJA_00060 6.6e-145 K Bacterial transcription activator, effector binding domain
HILOHAJA_00061 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HILOHAJA_00062 9.6e-112 ydfN C nitroreductase
HILOHAJA_00063 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HILOHAJA_00064 8.8e-63 mhqP S DoxX
HILOHAJA_00065 1.3e-57 traF CO Thioredoxin
HILOHAJA_00066 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HILOHAJA_00067 6.3e-29
HILOHAJA_00069 4.4e-118 ydfR S Protein of unknown function (DUF421)
HILOHAJA_00070 5.2e-122 ydfS S Protein of unknown function (DUF421)
HILOHAJA_00071 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
HILOHAJA_00072 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HILOHAJA_00073 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HILOHAJA_00074 4.2e-101 K Bacterial regulatory proteins, tetR family
HILOHAJA_00075 7.3e-53 S DoxX-like family
HILOHAJA_00076 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
HILOHAJA_00077 1.2e-307 expZ S ABC transporter
HILOHAJA_00078 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HILOHAJA_00079 2.3e-90 dinB S DinB family
HILOHAJA_00080 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
HILOHAJA_00081 0.0 ydgH S drug exporters of the RND superfamily
HILOHAJA_00082 1.2e-112 drgA C nitroreductase
HILOHAJA_00083 7.1e-69 ydgJ K Winged helix DNA-binding domain
HILOHAJA_00084 2.2e-208 tcaB EGP Major facilitator Superfamily
HILOHAJA_00085 1.2e-121 ydhB S membrane transporter protein
HILOHAJA_00086 6.5e-122 ydhC K FCD
HILOHAJA_00087 3.3e-244 ydhD M Glycosyl hydrolase
HILOHAJA_00088 9.1e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HILOHAJA_00089 1e-125
HILOHAJA_00090 9.9e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HILOHAJA_00091 8.7e-68 frataxin S Domain of unknown function (DU1801)
HILOHAJA_00093 5.2e-81 K Acetyltransferase (GNAT) domain
HILOHAJA_00094 1.9e-183 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HILOHAJA_00095 2.5e-98 ydhK M Protein of unknown function (DUF1541)
HILOHAJA_00096 4.6e-200 pbuE EGP Major facilitator Superfamily
HILOHAJA_00097 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HILOHAJA_00098 8.7e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HILOHAJA_00099 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HILOHAJA_00100 3.6e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HILOHAJA_00101 1.1e-132 ydhQ K UTRA
HILOHAJA_00102 6.6e-170 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HILOHAJA_00103 1.3e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HILOHAJA_00104 6.9e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HILOHAJA_00105 2.3e-156 ydhU P Catalase
HILOHAJA_00107 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HILOHAJA_00108 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HILOHAJA_00109 1.8e-37 yaaB S Domain of unknown function (DUF370)
HILOHAJA_00110 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HILOHAJA_00111 2.4e-33 yaaA S S4 domain
HILOHAJA_00112 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HILOHAJA_00113 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HILOHAJA_00114 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HILOHAJA_00115 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HILOHAJA_00116 6.5e-108 jag S single-stranded nucleic acid binding R3H
HILOHAJA_00117 2.2e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HILOHAJA_00118 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HILOHAJA_00119 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HILOHAJA_00120 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HILOHAJA_00121 9.6e-74 S Bacterial PH domain
HILOHAJA_00122 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HILOHAJA_00123 2.1e-149 spo0J K Belongs to the ParB family
HILOHAJA_00124 1.6e-111 yyaC S Sporulation protein YyaC
HILOHAJA_00125 2.3e-33 yyzM S protein conserved in bacteria
HILOHAJA_00126 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HILOHAJA_00127 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HILOHAJA_00128 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HILOHAJA_00129 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HILOHAJA_00130 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HILOHAJA_00131 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
HILOHAJA_00132 2.6e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HILOHAJA_00133 8.4e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILOHAJA_00134 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HILOHAJA_00135 1.8e-243 EGP Major facilitator superfamily
HILOHAJA_00136 8e-168 yyaK S CAAX protease self-immunity
HILOHAJA_00137 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HILOHAJA_00138 3.3e-161 yyaM EG EamA-like transporter family
HILOHAJA_00139 5.1e-61 yyaN K MerR HTH family regulatory protein
HILOHAJA_00140 2.6e-13 S Putative amidase domain
HILOHAJA_00142 2.4e-248 tetL EGP Major facilitator Superfamily
HILOHAJA_00143 6.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
HILOHAJA_00144 1e-65 yyaQ S YjbR
HILOHAJA_00145 3e-90 yyaR K Acetyltransferase (GNAT) domain
HILOHAJA_00146 2.5e-96 yyaS S Membrane
HILOHAJA_00147 1.2e-71 yjcF S Acetyltransferase (GNAT) domain
HILOHAJA_00148 5.6e-77 yybA 2.3.1.57 K transcriptional
HILOHAJA_00149 6.2e-125 S Metallo-beta-lactamase superfamily
HILOHAJA_00150 9.5e-75 yybC
HILOHAJA_00151 2.9e-78 yjcF S Acetyltransferase (GNAT) domain
HILOHAJA_00152 1.1e-164 yybE K Transcriptional regulator
HILOHAJA_00153 6.3e-216 ynfM EGP Major facilitator Superfamily
HILOHAJA_00154 7.4e-123 yybG S Pentapeptide repeat-containing protein
HILOHAJA_00155 2.8e-64 yybH S SnoaL-like domain
HILOHAJA_00156 2.8e-124
HILOHAJA_00157 2.2e-110 K TipAS antibiotic-recognition domain
HILOHAJA_00158 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HILOHAJA_00160 3.6e-60
HILOHAJA_00161 8.1e-163 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HILOHAJA_00162 1.7e-66 ydeP3 K Transcriptional regulator
HILOHAJA_00163 3.3e-83 cotF M Spore coat protein
HILOHAJA_00165 8.3e-160 yybS S membrane
HILOHAJA_00166 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HILOHAJA_00167 2.2e-73 rplI J binds to the 23S rRNA
HILOHAJA_00168 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HILOHAJA_00169 1.2e-219 yeaN P COG2807 Cyanate permease
HILOHAJA_00170 1.9e-15 yycC K YycC-like protein
HILOHAJA_00172 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HILOHAJA_00173 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HILOHAJA_00174 3.4e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILOHAJA_00175 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HILOHAJA_00177 2.9e-31
HILOHAJA_00178 6.6e-10
HILOHAJA_00181 4.2e-17 S Terminase
HILOHAJA_00182 5.2e-79 L phage terminase small subunit
HILOHAJA_00184 6.1e-35
HILOHAJA_00185 3.1e-27 S PFAM FRG domain
HILOHAJA_00186 7.2e-44 wecC 1.1.1.336 M ArpU family transcriptional regulator
HILOHAJA_00188 1.7e-21
HILOHAJA_00189 2.9e-102 dnaB 3.6.4.12 L replicative DNA helicase
HILOHAJA_00190 2.3e-38 L Arm DNA-binding domain
HILOHAJA_00191 4.3e-68 glnR K transcriptional
HILOHAJA_00192 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HILOHAJA_00193 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HILOHAJA_00194 1.7e-176 spoVK O stage V sporulation protein K
HILOHAJA_00195 2.3e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HILOHAJA_00196 2e-109 ymaB
HILOHAJA_00197 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HILOHAJA_00198 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HILOHAJA_00199 1.6e-48 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HILOHAJA_00200 4.5e-22 ymzA
HILOHAJA_00201 3.1e-22
HILOHAJA_00202 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HILOHAJA_00203 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HILOHAJA_00204 2.1e-46 ymaF S YmaF family
HILOHAJA_00206 4.9e-51 ebrA P Small Multidrug Resistance protein
HILOHAJA_00207 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HILOHAJA_00208 4.6e-79 ymaD O redox protein, regulator of disulfide bond formation
HILOHAJA_00209 2.1e-126 ymaC S Replication protein
HILOHAJA_00210 1.9e-07 K Transcriptional regulator
HILOHAJA_00211 4.6e-252 aprX O Belongs to the peptidase S8 family
HILOHAJA_00212 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
HILOHAJA_00213 4.4e-61 ymzB
HILOHAJA_00214 2.2e-232 cypA C Cytochrome P450
HILOHAJA_00215 0.0 pks13 HQ Beta-ketoacyl synthase
HILOHAJA_00216 0.0 dhbF IQ polyketide synthase
HILOHAJA_00217 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HILOHAJA_00218 0.0 pfaA Q Polyketide synthase of type I
HILOHAJA_00219 0.0 rhiB IQ polyketide synthase
HILOHAJA_00220 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HILOHAJA_00221 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
HILOHAJA_00222 1.3e-245 pksG 2.3.3.10 I synthase
HILOHAJA_00223 8.7e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HILOHAJA_00224 1.4e-37 acpK IQ Phosphopantetheine attachment site
HILOHAJA_00225 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HILOHAJA_00226 1.5e-183 pksD Q Acyl transferase domain
HILOHAJA_00228 4.1e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HILOHAJA_00229 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HILOHAJA_00230 4.4e-109 pksA K Transcriptional regulator
HILOHAJA_00231 8.7e-96 ymcC S Membrane
HILOHAJA_00233 8.9e-70 S Regulatory protein YrvL
HILOHAJA_00234 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HILOHAJA_00235 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HILOHAJA_00236 2.2e-88 cotE S Spore coat protein
HILOHAJA_00237 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HILOHAJA_00238 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HILOHAJA_00239 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HILOHAJA_00240 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HILOHAJA_00241 1.2e-36 spoVS S Stage V sporulation protein S
HILOHAJA_00242 1.9e-152 ymdB S protein conserved in bacteria
HILOHAJA_00243 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HILOHAJA_00244 1e-215 pbpX V Beta-lactamase
HILOHAJA_00245 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HILOHAJA_00246 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
HILOHAJA_00247 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HILOHAJA_00248 1.9e-124 ymfM S protein conserved in bacteria
HILOHAJA_00249 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HILOHAJA_00250 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HILOHAJA_00251 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HILOHAJA_00252 1.4e-242 ymfH S zinc protease
HILOHAJA_00253 1.4e-234 ymfF S Peptidase M16
HILOHAJA_00254 3.4e-206 ymfD EGP Major facilitator Superfamily
HILOHAJA_00255 1.4e-133 ymfC K Transcriptional regulator
HILOHAJA_00256 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HILOHAJA_00257 2.9e-31 S YlzJ-like protein
HILOHAJA_00258 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HILOHAJA_00259 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HILOHAJA_00260 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HILOHAJA_00261 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HILOHAJA_00262 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HILOHAJA_00263 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HILOHAJA_00264 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HILOHAJA_00265 2.6e-42 ymxH S YlmC YmxH family
HILOHAJA_00266 4.4e-233 pepR S Belongs to the peptidase M16 family
HILOHAJA_00267 2.8e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HILOHAJA_00268 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HILOHAJA_00269 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HILOHAJA_00270 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HILOHAJA_00271 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HILOHAJA_00272 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HILOHAJA_00273 3e-44 ylxP S protein conserved in bacteria
HILOHAJA_00274 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HILOHAJA_00275 3.1e-47 ylxQ J ribosomal protein
HILOHAJA_00276 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HILOHAJA_00277 1.1e-203 nusA K Participates in both transcription termination and antitermination
HILOHAJA_00278 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HILOHAJA_00279 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HILOHAJA_00280 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HILOHAJA_00281 7.7e-233 rasP M zinc metalloprotease
HILOHAJA_00282 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HILOHAJA_00283 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HILOHAJA_00284 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HILOHAJA_00285 3.2e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HILOHAJA_00286 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HILOHAJA_00287 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HILOHAJA_00288 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HILOHAJA_00289 3.1e-76 ylxL
HILOHAJA_00290 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILOHAJA_00291 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HILOHAJA_00292 2.2e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HILOHAJA_00293 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HILOHAJA_00294 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HILOHAJA_00295 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HILOHAJA_00296 2.2e-157 flhG D Belongs to the ParA family
HILOHAJA_00297 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
HILOHAJA_00298 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HILOHAJA_00299 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HILOHAJA_00300 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HILOHAJA_00301 2.2e-36 fliQ N Role in flagellar biosynthesis
HILOHAJA_00302 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HILOHAJA_00303 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
HILOHAJA_00304 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HILOHAJA_00305 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HILOHAJA_00306 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HILOHAJA_00307 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HILOHAJA_00308 8.2e-140 flgG N Flagellar basal body rod
HILOHAJA_00309 1.7e-72 flgD N Flagellar basal body rod modification protein
HILOHAJA_00310 8.1e-202 fliK N Flagellar hook-length control protein
HILOHAJA_00311 7.7e-37 ylxF S MgtE intracellular N domain
HILOHAJA_00312 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HILOHAJA_00313 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HILOHAJA_00314 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HILOHAJA_00315 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HILOHAJA_00316 2.4e-255 fliF N The M ring may be actively involved in energy transduction
HILOHAJA_00317 1.9e-31 fliE N Flagellar hook-basal body
HILOHAJA_00318 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
HILOHAJA_00319 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HILOHAJA_00320 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HILOHAJA_00321 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HILOHAJA_00322 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HILOHAJA_00323 2.5e-169 xerC L tyrosine recombinase XerC
HILOHAJA_00324 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HILOHAJA_00325 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HILOHAJA_00326 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HILOHAJA_00327 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HILOHAJA_00328 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HILOHAJA_00329 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HILOHAJA_00330 5.5e-290 ylqG
HILOHAJA_00331 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HILOHAJA_00332 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HILOHAJA_00333 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HILOHAJA_00334 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HILOHAJA_00335 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HILOHAJA_00336 1.8e-60 ylqD S YlqD protein
HILOHAJA_00337 1.2e-36 ylqC S Belongs to the UPF0109 family
HILOHAJA_00338 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HILOHAJA_00339 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HILOHAJA_00340 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HILOHAJA_00341 3.2e-86
HILOHAJA_00342 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HILOHAJA_00343 0.0 smc D Required for chromosome condensation and partitioning
HILOHAJA_00344 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HILOHAJA_00345 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HILOHAJA_00346 6.1e-129 IQ reductase
HILOHAJA_00347 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HILOHAJA_00348 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HILOHAJA_00349 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HILOHAJA_00350 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HILOHAJA_00351 2.7e-155 sdaAA 4.3.1.17 E L-serine dehydratase
HILOHAJA_00352 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HILOHAJA_00353 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
HILOHAJA_00354 5.5e-59 asp S protein conserved in bacteria
HILOHAJA_00355 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HILOHAJA_00356 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HILOHAJA_00357 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HILOHAJA_00358 1.9e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HILOHAJA_00359 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HILOHAJA_00360 2.7e-140 stp 3.1.3.16 T phosphatase
HILOHAJA_00361 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HILOHAJA_00362 4.2e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HILOHAJA_00363 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HILOHAJA_00364 1.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HILOHAJA_00365 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HILOHAJA_00366 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HILOHAJA_00367 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HILOHAJA_00368 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HILOHAJA_00369 1.5e-40 ylzA S Belongs to the UPF0296 family
HILOHAJA_00370 3.1e-156 yloC S stress-induced protein
HILOHAJA_00371 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HILOHAJA_00372 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HILOHAJA_00373 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HILOHAJA_00374 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HILOHAJA_00375 5.9e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HILOHAJA_00376 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HILOHAJA_00377 1.1e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HILOHAJA_00378 4.1e-179 cysP P phosphate transporter
HILOHAJA_00379 1.9e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HILOHAJA_00381 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HILOHAJA_00382 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HILOHAJA_00383 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HILOHAJA_00384 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HILOHAJA_00385 0.0 carB 6.3.5.5 F Belongs to the CarB family
HILOHAJA_00386 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HILOHAJA_00387 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HILOHAJA_00388 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HILOHAJA_00389 6.4e-230 pyrP F Xanthine uracil
HILOHAJA_00390 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HILOHAJA_00391 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HILOHAJA_00392 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HILOHAJA_00393 1.3e-63 dksA T COG1734 DnaK suppressor protein
HILOHAJA_00394 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HILOHAJA_00395 2.6e-67 divIVA D Cell division initiation protein
HILOHAJA_00396 9.7e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HILOHAJA_00397 1.6e-39 yggT S membrane
HILOHAJA_00398 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HILOHAJA_00399 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HILOHAJA_00400 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HILOHAJA_00401 2.4e-37 ylmC S sporulation protein
HILOHAJA_00402 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
HILOHAJA_00403 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HILOHAJA_00404 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILOHAJA_00405 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILOHAJA_00406 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HILOHAJA_00407 0.0 bpr O COG1404 Subtilisin-like serine proteases
HILOHAJA_00408 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HILOHAJA_00409 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HILOHAJA_00410 6.2e-58 sbp S small basic protein
HILOHAJA_00411 5.1e-102 ylxX S protein conserved in bacteria
HILOHAJA_00412 2.4e-103 ylxW S protein conserved in bacteria
HILOHAJA_00413 1.7e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HILOHAJA_00414 5.3e-167 murB 1.3.1.98 M cell wall formation
HILOHAJA_00415 1.6e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HILOHAJA_00416 5.7e-186 spoVE D Belongs to the SEDS family
HILOHAJA_00417 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HILOHAJA_00418 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HILOHAJA_00419 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HILOHAJA_00420 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HILOHAJA_00421 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HILOHAJA_00422 3.7e-44 ftsL D Essential cell division protein
HILOHAJA_00423 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HILOHAJA_00424 2.9e-78 mraZ K Belongs to the MraZ family
HILOHAJA_00425 7.4e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HILOHAJA_00426 1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HILOHAJA_00427 1.5e-88 ylbP K n-acetyltransferase
HILOHAJA_00428 1.3e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HILOHAJA_00429 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HILOHAJA_00430 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HILOHAJA_00432 1.1e-234 ylbM S Belongs to the UPF0348 family
HILOHAJA_00433 2e-186 ylbL T Belongs to the peptidase S16 family
HILOHAJA_00434 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
HILOHAJA_00435 1.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
HILOHAJA_00436 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HILOHAJA_00437 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
HILOHAJA_00438 3.7e-38 ylbG S UPF0298 protein
HILOHAJA_00439 1.8e-75 ylbF S Belongs to the UPF0342 family
HILOHAJA_00440 6.7e-37 ylbE S YlbE-like protein
HILOHAJA_00441 4.1e-63 ylbD S Putative coat protein
HILOHAJA_00442 3e-201 ylbC S protein with SCP PR1 domains
HILOHAJA_00443 2.6e-74 ylbB T COG0517 FOG CBS domain
HILOHAJA_00444 7e-62 ylbA S YugN-like family
HILOHAJA_00445 5.7e-166 ctaG S cytochrome c oxidase
HILOHAJA_00446 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HILOHAJA_00447 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HILOHAJA_00448 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HILOHAJA_00449 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HILOHAJA_00450 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HILOHAJA_00451 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HILOHAJA_00452 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HILOHAJA_00453 4.5e-214 ftsW D Belongs to the SEDS family
HILOHAJA_00454 8.7e-44 ylaN S Belongs to the UPF0358 family
HILOHAJA_00455 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HILOHAJA_00456 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HILOHAJA_00457 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HILOHAJA_00458 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HILOHAJA_00459 2.5e-32 ylaI S protein conserved in bacteria
HILOHAJA_00460 4.2e-47 ylaH S YlaH-like protein
HILOHAJA_00461 0.0 typA T GTP-binding protein TypA
HILOHAJA_00462 8.2e-22 S Family of unknown function (DUF5325)
HILOHAJA_00463 1.8e-38 ylaE
HILOHAJA_00464 7.1e-12 sigC S Putative zinc-finger
HILOHAJA_00465 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HILOHAJA_00466 2.7e-42 ylaB
HILOHAJA_00467 0.0 ylaA
HILOHAJA_00468 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HILOHAJA_00469 1.9e-169 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HILOHAJA_00470 4.4e-77 ykzC S Acetyltransferase (GNAT) family
HILOHAJA_00471 4.3e-149 suhB 3.1.3.25 G Inositol monophosphatase
HILOHAJA_00472 7.2e-26 ykzI
HILOHAJA_00473 2.1e-117 yktB S Belongs to the UPF0637 family
HILOHAJA_00474 2e-42 yktA S Belongs to the UPF0223 family
HILOHAJA_00475 1.3e-276 speA 4.1.1.19 E Arginine
HILOHAJA_00476 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HILOHAJA_00477 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HILOHAJA_00478 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HILOHAJA_00479 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HILOHAJA_00480 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HILOHAJA_00481 2e-115 recN L Putative cell-wall binding lipoprotein
HILOHAJA_00483 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HILOHAJA_00484 1.4e-147 ykrA S hydrolases of the HAD superfamily
HILOHAJA_00485 8.2e-31 ykzG S Belongs to the UPF0356 family
HILOHAJA_00486 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HILOHAJA_00487 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HILOHAJA_00488 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HILOHAJA_00489 6.5e-156 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HILOHAJA_00490 1.3e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HILOHAJA_00491 1.5e-43 abrB K of stationary sporulation gene expression
HILOHAJA_00492 7.7e-183 mreB D Rod-share determining protein MreBH
HILOHAJA_00493 5.5e-12 S Uncharacterized protein YkpC
HILOHAJA_00494 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HILOHAJA_00495 2e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HILOHAJA_00496 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HILOHAJA_00497 8.1e-39 ykoA
HILOHAJA_00498 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HILOHAJA_00499 9.2e-304 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HILOHAJA_00500 2.9e-76 ctsR K Belongs to the CtsR family
HILOHAJA_00501 1.8e-46 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HILOHAJA_00502 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HILOHAJA_00503 0.0 clpC O Belongs to the ClpA ClpB family
HILOHAJA_00504 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HILOHAJA_00505 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HILOHAJA_00506 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HILOHAJA_00507 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HILOHAJA_00508 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HILOHAJA_00509 3.3e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HILOHAJA_00510 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HILOHAJA_00511 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HILOHAJA_00512 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HILOHAJA_00513 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HILOHAJA_00514 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HILOHAJA_00515 4.4e-115 sigH K Belongs to the sigma-70 factor family
HILOHAJA_00516 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HILOHAJA_00517 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HILOHAJA_00518 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HILOHAJA_00519 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HILOHAJA_00520 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HILOHAJA_00521 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HILOHAJA_00522 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HILOHAJA_00523 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HILOHAJA_00524 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HILOHAJA_00525 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HILOHAJA_00526 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HILOHAJA_00527 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HILOHAJA_00528 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HILOHAJA_00529 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HILOHAJA_00530 1.1e-178 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HILOHAJA_00531 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HILOHAJA_00532 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HILOHAJA_00533 3e-105 rplD J Forms part of the polypeptide exit tunnel
HILOHAJA_00534 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HILOHAJA_00535 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HILOHAJA_00536 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HILOHAJA_00537 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HILOHAJA_00538 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HILOHAJA_00539 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HILOHAJA_00540 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HILOHAJA_00541 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HILOHAJA_00542 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HILOHAJA_00543 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HILOHAJA_00544 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HILOHAJA_00545 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HILOHAJA_00546 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HILOHAJA_00547 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HILOHAJA_00548 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HILOHAJA_00549 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HILOHAJA_00550 1.9e-23 rpmD J Ribosomal protein L30
HILOHAJA_00551 1.8e-72 rplO J binds to the 23S rRNA
HILOHAJA_00552 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HILOHAJA_00553 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HILOHAJA_00554 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HILOHAJA_00555 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HILOHAJA_00556 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HILOHAJA_00557 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HILOHAJA_00558 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HILOHAJA_00559 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HILOHAJA_00560 3.6e-58 rplQ J Ribosomal protein L17
HILOHAJA_00561 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HILOHAJA_00562 9.7e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HILOHAJA_00563 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HILOHAJA_00564 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HILOHAJA_00565 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HILOHAJA_00566 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HILOHAJA_00567 2.4e-144 ybaJ Q Methyltransferase domain
HILOHAJA_00568 1.4e-64 ybaK S Protein of unknown function (DUF2521)
HILOHAJA_00569 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HILOHAJA_00570 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HILOHAJA_00571 1.2e-84 gerD
HILOHAJA_00572 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HILOHAJA_00573 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HILOHAJA_00574 6e-27
HILOHAJA_00575 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HILOHAJA_00577 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HILOHAJA_00578 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HILOHAJA_00579 2.4e-311 recN L May be involved in recombinational repair of damaged DNA
HILOHAJA_00580 1.7e-78 argR K Regulates arginine biosynthesis genes
HILOHAJA_00581 1.5e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HILOHAJA_00582 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HILOHAJA_00583 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HILOHAJA_00584 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HILOHAJA_00585 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HILOHAJA_00586 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HILOHAJA_00587 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HILOHAJA_00588 2.1e-67 yqhY S protein conserved in bacteria
HILOHAJA_00589 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HILOHAJA_00590 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HILOHAJA_00591 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HILOHAJA_00592 2.2e-109 spoIIIAG S stage III sporulation protein AG
HILOHAJA_00593 9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HILOHAJA_00594 2.9e-197 spoIIIAE S stage III sporulation protein AE
HILOHAJA_00595 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HILOHAJA_00596 7.6e-29 spoIIIAC S stage III sporulation protein AC
HILOHAJA_00597 3.2e-84 spoIIIAB S Stage III sporulation protein
HILOHAJA_00598 3e-170 spoIIIAA S stage III sporulation protein AA
HILOHAJA_00599 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HILOHAJA_00600 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HILOHAJA_00601 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HILOHAJA_00602 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HILOHAJA_00603 2.3e-93 yqhR S Conserved membrane protein YqhR
HILOHAJA_00604 8e-174 yqhQ S Protein of unknown function (DUF1385)
HILOHAJA_00605 2.2e-61 yqhP
HILOHAJA_00606 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
HILOHAJA_00607 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HILOHAJA_00608 4e-50 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HILOHAJA_00609 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HILOHAJA_00610 1.4e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HILOHAJA_00611 1.1e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HILOHAJA_00612 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HILOHAJA_00613 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HILOHAJA_00614 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HILOHAJA_00615 1.2e-24 sinI S Anti-repressor SinI
HILOHAJA_00616 1e-54 sinR K transcriptional
HILOHAJA_00617 1.2e-140 tasA S Cell division protein FtsN
HILOHAJA_00618 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HILOHAJA_00619 2.7e-116 yqxM
HILOHAJA_00620 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HILOHAJA_00621 1.4e-26 yqzE S YqzE-like protein
HILOHAJA_00622 2e-43 S ComG operon protein 7
HILOHAJA_00623 2.9e-34 comGF U Putative Competence protein ComGF
HILOHAJA_00624 1.1e-59 comGE
HILOHAJA_00625 7.7e-68 gspH NU protein transport across the cell outer membrane
HILOHAJA_00626 5.2e-47 comGC U Required for transformation and DNA binding
HILOHAJA_00627 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
HILOHAJA_00628 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HILOHAJA_00631 7.2e-175 corA P Mg2 transporter protein
HILOHAJA_00632 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HILOHAJA_00633 1.2e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HILOHAJA_00635 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HILOHAJA_00636 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HILOHAJA_00637 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HILOHAJA_00638 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HILOHAJA_00639 6.9e-50 yqgV S Thiamine-binding protein
HILOHAJA_00640 2.7e-199 yqgU
HILOHAJA_00641 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HILOHAJA_00642 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HILOHAJA_00643 5.2e-181 glcK 2.7.1.2 G Glucokinase
HILOHAJA_00644 4.3e-33 yqgQ S Protein conserved in bacteria
HILOHAJA_00645 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HILOHAJA_00646 2.5e-09 yqgO
HILOHAJA_00647 4.8e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HILOHAJA_00648 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HILOHAJA_00649 4.3e-200 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HILOHAJA_00651 4.6e-50 yqzD
HILOHAJA_00652 2.1e-71 yqzC S YceG-like family
HILOHAJA_00653 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HILOHAJA_00654 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HILOHAJA_00655 4.4e-158 pstA P Phosphate transport system permease
HILOHAJA_00656 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
HILOHAJA_00657 5.3e-151 pstS P Phosphate
HILOHAJA_00658 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HILOHAJA_00659 2.5e-231 yqgE EGP Major facilitator superfamily
HILOHAJA_00660 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HILOHAJA_00661 4e-73 yqgC S protein conserved in bacteria
HILOHAJA_00662 8.5e-134 yqgB S Protein of unknown function (DUF1189)
HILOHAJA_00663 2.2e-75 yqgA
HILOHAJA_00664 5.2e-47 yqfZ M LysM domain
HILOHAJA_00665 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HILOHAJA_00666 4.3e-62 yqfX S membrane
HILOHAJA_00667 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HILOHAJA_00668 1.9e-77 zur P Belongs to the Fur family
HILOHAJA_00669 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HILOHAJA_00670 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HILOHAJA_00671 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HILOHAJA_00672 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HILOHAJA_00673 2.9e-14 yqfQ S YqfQ-like protein
HILOHAJA_00674 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HILOHAJA_00675 1.3e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HILOHAJA_00676 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
HILOHAJA_00677 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HILOHAJA_00678 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HILOHAJA_00679 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HILOHAJA_00680 4.5e-88 yaiI S Belongs to the UPF0178 family
HILOHAJA_00681 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HILOHAJA_00682 4.5e-112 ccpN K CBS domain
HILOHAJA_00683 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HILOHAJA_00684 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HILOHAJA_00685 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
HILOHAJA_00686 8.4e-19 S YqzL-like protein
HILOHAJA_00687 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HILOHAJA_00688 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HILOHAJA_00689 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HILOHAJA_00690 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HILOHAJA_00691 0.0 yqfF S membrane-associated HD superfamily hydrolase
HILOHAJA_00693 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HILOHAJA_00694 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HILOHAJA_00695 2.7e-45 yqfC S sporulation protein YqfC
HILOHAJA_00696 3.7e-22 yqfB
HILOHAJA_00697 4.3e-122 yqfA S UPF0365 protein
HILOHAJA_00698 4.5e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HILOHAJA_00699 2.5e-61 yqeY S Yqey-like protein
HILOHAJA_00700 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HILOHAJA_00701 2.3e-157 yqeW P COG1283 Na phosphate symporter
HILOHAJA_00702 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HILOHAJA_00703 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HILOHAJA_00704 6e-174 prmA J Methylates ribosomal protein L11
HILOHAJA_00705 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HILOHAJA_00706 0.0 dnaK O Heat shock 70 kDa protein
HILOHAJA_00707 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HILOHAJA_00708 6.2e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HILOHAJA_00709 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HILOHAJA_00710 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HILOHAJA_00711 7.2e-53 yqxA S Protein of unknown function (DUF3679)
HILOHAJA_00712 2.9e-221 spoIIP M stage II sporulation protein P
HILOHAJA_00713 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HILOHAJA_00714 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HILOHAJA_00715 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HILOHAJA_00716 4.1e-15 S YqzM-like protein
HILOHAJA_00717 0.0 comEC S Competence protein ComEC
HILOHAJA_00718 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HILOHAJA_00719 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HILOHAJA_00720 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HILOHAJA_00721 2.9e-139 yqeM Q Methyltransferase
HILOHAJA_00722 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HILOHAJA_00723 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HILOHAJA_00724 1.3e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HILOHAJA_00725 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HILOHAJA_00726 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HILOHAJA_00727 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HILOHAJA_00728 5.3e-95 yqeG S hydrolase of the HAD superfamily
HILOHAJA_00730 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HILOHAJA_00731 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HILOHAJA_00732 2.3e-105 yqeD S SNARE associated Golgi protein
HILOHAJA_00733 3.8e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HILOHAJA_00734 3e-133 yqeB
HILOHAJA_00735 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HILOHAJA_00736 2.8e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILOHAJA_00737 1.8e-62 napB K helix_turn_helix multiple antibiotic resistance protein
HILOHAJA_00738 1.4e-219 yfjF U Belongs to the major facilitator superfamily
HILOHAJA_00739 1.3e-276 cisA2 L Recombinase
HILOHAJA_00740 4e-177 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HILOHAJA_00743 3.8e-130 S Aspartate phosphatase response regulator
HILOHAJA_00744 1.1e-169 yobL S Bacterial EndoU nuclease
HILOHAJA_00745 1.5e-40
HILOHAJA_00746 5.9e-39
HILOHAJA_00747 2.2e-25 S SMI1 / KNR4 family
HILOHAJA_00748 5.4e-11 S SMI1-KNR4 cell-wall
HILOHAJA_00749 2.1e-70 yokH G SMI1 / KNR4 family
HILOHAJA_00750 2.4e-56 V HNH endonuclease
HILOHAJA_00751 4.8e-127 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HILOHAJA_00752 1.6e-27 S phage terminase, large subunit
HILOHAJA_00753 1.4e-29 yqaS L DNA packaging
HILOHAJA_00754 2.3e-33 yqaS L DNA packaging
HILOHAJA_00757 3.9e-22
HILOHAJA_00758 8.7e-78 L Transposase
HILOHAJA_00760 1.4e-18 wapA M RHS family
HILOHAJA_00761 1.8e-30 yqaO S Phage-like element PBSX protein XtrA
HILOHAJA_00762 7.2e-42 rusA L Endodeoxyribonuclease RusA
HILOHAJA_00765 1.4e-147 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HILOHAJA_00766 7.9e-89 K Transcriptional regulator PadR-like family
HILOHAJA_00767 2.9e-96 adk 2.7.4.3 F adenylate kinase activity
HILOHAJA_00769 4e-95 yqaB E IrrE N-terminal-like domain
HILOHAJA_00770 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILOHAJA_00771 2e-68 psiE S Protein PsiE homolog
HILOHAJA_00772 4.5e-236 yrkQ T Histidine kinase
HILOHAJA_00773 1.1e-127 T Transcriptional regulator
HILOHAJA_00774 8.2e-224 yrkO P Protein of unknown function (DUF418)
HILOHAJA_00775 1.1e-103 yrkN K Acetyltransferase (GNAT) family
HILOHAJA_00776 1.5e-97 ywrO S Flavodoxin-like fold
HILOHAJA_00777 2.8e-79 S Protein of unknown function with HXXEE motif
HILOHAJA_00778 5.4e-112 yrkJ S membrane transporter protein
HILOHAJA_00779 2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
HILOHAJA_00780 3e-204 yrkH P Rhodanese Homology Domain
HILOHAJA_00781 4.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
HILOHAJA_00782 4.3e-83 yrkE O DsrE/DsrF/DrsH-like family
HILOHAJA_00783 7.8e-39 yrkD S protein conserved in bacteria
HILOHAJA_00784 4.9e-107 yrkC G Cupin domain
HILOHAJA_00785 1.2e-149 bltR K helix_turn_helix, mercury resistance
HILOHAJA_00786 1.3e-210 blt EGP Major facilitator Superfamily
HILOHAJA_00787 7.7e-82 bltD 2.3.1.57 K FR47-like protein
HILOHAJA_00788 2.5e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HILOHAJA_00789 3.9e-16 S YrzO-like protein
HILOHAJA_00790 2.7e-169 yrdR EG EamA-like transporter family
HILOHAJA_00791 1.5e-158 yrdQ K Transcriptional regulator
HILOHAJA_00792 3.9e-198 trkA P Oxidoreductase
HILOHAJA_00793 1.3e-152 czcD P COG1230 Co Zn Cd efflux system component
HILOHAJA_00794 4.2e-65 yodA S tautomerase
HILOHAJA_00795 5e-162 gltR K LysR substrate binding domain
HILOHAJA_00796 5.6e-226 brnQ E Component of the transport system for branched-chain amino acids
HILOHAJA_00797 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HILOHAJA_00798 1.1e-136 azlC E AzlC protein
HILOHAJA_00799 6.9e-78 bkdR K helix_turn_helix ASNC type
HILOHAJA_00800 2.2e-32 yrdF K ribonuclease inhibitor
HILOHAJA_00801 2e-225 cypA C Cytochrome P450
HILOHAJA_00802 1.9e-23 K Acetyltransferase (GNAT) family
HILOHAJA_00803 5e-99 yrdC 3.5.1.19 Q Isochorismatase family
HILOHAJA_00804 1.4e-89 yrdA S DinB family
HILOHAJA_00805 2.7e-165 aadK G Streptomycin adenylyltransferase
HILOHAJA_00806 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HILOHAJA_00807 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HILOHAJA_00808 1.6e-123 yrpD S Domain of unknown function, YrpD
HILOHAJA_00810 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HILOHAJA_00811 2.4e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HILOHAJA_00812 1.3e-187 yrpG C Aldo/keto reductase family
HILOHAJA_00813 8.9e-224 yraO C Citrate transporter
HILOHAJA_00814 3.4e-163 yraN K Transcriptional regulator
HILOHAJA_00815 1.6e-205 yraM S PrpF protein
HILOHAJA_00817 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HILOHAJA_00818 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILOHAJA_00819 2.3e-153 S Alpha beta hydrolase
HILOHAJA_00820 2.2e-60 T sh3 domain protein
HILOHAJA_00821 2.4e-61 T sh3 domain protein
HILOHAJA_00823 3.8e-66 E Glyoxalase-like domain
HILOHAJA_00824 1.5e-36 yraG
HILOHAJA_00825 6.4e-63 yraF M Spore coat protein
HILOHAJA_00826 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HILOHAJA_00827 7.5e-26 yraE
HILOHAJA_00828 1.1e-49 yraD M Spore coat protein
HILOHAJA_00829 4.3e-47 yraB K helix_turn_helix, mercury resistance
HILOHAJA_00830 3.5e-199 adhA 1.1.1.1 C alcohol dehydrogenase
HILOHAJA_00831 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HILOHAJA_00832 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HILOHAJA_00833 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HILOHAJA_00834 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HILOHAJA_00835 6.9e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HILOHAJA_00836 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
HILOHAJA_00837 0.0 levR K PTS system fructose IIA component
HILOHAJA_00838 2.1e-252 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HILOHAJA_00839 1.1e-105 yrhP E LysE type translocator
HILOHAJA_00840 1.2e-149 yrhO K Archaeal transcriptional regulator TrmB
HILOHAJA_00841 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HILOHAJA_00842 9.4e-150 rsiV S Protein of unknown function (DUF3298)
HILOHAJA_00843 0.0 yrhL I Acyltransferase family
HILOHAJA_00844 1.5e-46 yrhK S YrhK-like protein
HILOHAJA_00845 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HILOHAJA_00846 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HILOHAJA_00847 4.5e-97 yrhH Q methyltransferase
HILOHAJA_00850 1.8e-142 focA P Formate nitrite
HILOHAJA_00851 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HILOHAJA_00852 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HILOHAJA_00853 1.4e-78 yrhD S Protein of unknown function (DUF1641)
HILOHAJA_00854 4.6e-35 yrhC S YrhC-like protein
HILOHAJA_00855 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HILOHAJA_00856 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HILOHAJA_00857 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HILOHAJA_00858 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HILOHAJA_00859 3.5e-26 yrzA S Protein of unknown function (DUF2536)
HILOHAJA_00860 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HILOHAJA_00861 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HILOHAJA_00862 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HILOHAJA_00863 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HILOHAJA_00864 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HILOHAJA_00865 7.8e-174 yegQ O Peptidase U32
HILOHAJA_00866 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
HILOHAJA_00867 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HILOHAJA_00868 1.2e-45 yrzB S Belongs to the UPF0473 family
HILOHAJA_00869 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HILOHAJA_00870 1.7e-41 yrzL S Belongs to the UPF0297 family
HILOHAJA_00871 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HILOHAJA_00872 2.7e-170 yrrI S AI-2E family transporter
HILOHAJA_00873 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HILOHAJA_00874 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
HILOHAJA_00875 3.6e-109 gluC P ABC transporter
HILOHAJA_00876 7.6e-107 glnP P ABC transporter
HILOHAJA_00877 8e-08 S Protein of unknown function (DUF3918)
HILOHAJA_00878 9.8e-31 yrzR
HILOHAJA_00879 1.8e-83 yrrD S protein conserved in bacteria
HILOHAJA_00880 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HILOHAJA_00881 1.4e-15 S COG0457 FOG TPR repeat
HILOHAJA_00882 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HILOHAJA_00883 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
HILOHAJA_00884 1.2e-70 cymR K Transcriptional regulator
HILOHAJA_00885 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HILOHAJA_00886 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HILOHAJA_00887 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HILOHAJA_00888 2.4e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
HILOHAJA_00890 6.3e-261 lytH 3.5.1.28 M COG3103 SH3 domain protein
HILOHAJA_00891 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HILOHAJA_00892 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HILOHAJA_00893 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HILOHAJA_00894 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HILOHAJA_00895 3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HILOHAJA_00896 1.2e-85 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HILOHAJA_00897 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HILOHAJA_00898 9.4e-49 yrzD S Post-transcriptional regulator
HILOHAJA_00899 1.7e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HILOHAJA_00900 1.9e-113 yrbG S membrane
HILOHAJA_00901 7.6e-74 yrzE S Protein of unknown function (DUF3792)
HILOHAJA_00902 8e-39 yajC U Preprotein translocase subunit YajC
HILOHAJA_00903 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HILOHAJA_00904 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HILOHAJA_00905 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HILOHAJA_00906 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HILOHAJA_00907 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HILOHAJA_00908 4.8e-93 bofC S BofC C-terminal domain
HILOHAJA_00909 5.3e-253 csbX EGP Major facilitator Superfamily
HILOHAJA_00910 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HILOHAJA_00911 6.5e-119 yrzF T serine threonine protein kinase
HILOHAJA_00913 6.8e-51 S Family of unknown function (DUF5412)
HILOHAJA_00914 1.8e-262 alsT E Sodium alanine symporter
HILOHAJA_00915 4.2e-127 yebC K transcriptional regulatory protein
HILOHAJA_00916 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HILOHAJA_00917 9.8e-158 safA M spore coat assembly protein SafA
HILOHAJA_00918 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HILOHAJA_00919 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HILOHAJA_00920 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HILOHAJA_00921 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
HILOHAJA_00922 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HILOHAJA_00923 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
HILOHAJA_00924 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HILOHAJA_00925 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HILOHAJA_00926 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HILOHAJA_00927 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HILOHAJA_00928 4.1e-56 ysxB J ribosomal protein
HILOHAJA_00929 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HILOHAJA_00930 9.2e-161 spoIVFB S Stage IV sporulation protein
HILOHAJA_00931 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HILOHAJA_00932 2.5e-144 minD D Belongs to the ParA family
HILOHAJA_00933 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HILOHAJA_00934 1.4e-84 mreD M shape-determining protein
HILOHAJA_00935 4e-156 mreC M Involved in formation and maintenance of cell shape
HILOHAJA_00936 1.8e-184 mreB D Rod shape-determining protein MreB
HILOHAJA_00937 5.9e-126 radC E Belongs to the UPF0758 family
HILOHAJA_00938 2.8e-102 maf D septum formation protein Maf
HILOHAJA_00939 1.1e-168 spoIIB S Sporulation related domain
HILOHAJA_00940 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HILOHAJA_00941 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HILOHAJA_00942 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HILOHAJA_00943 1.6e-25
HILOHAJA_00944 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HILOHAJA_00945 1.9e-226 spoVID M stage VI sporulation protein D
HILOHAJA_00946 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HILOHAJA_00947 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
HILOHAJA_00948 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HILOHAJA_00949 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HILOHAJA_00950 3.6e-146 hemX O cytochrome C
HILOHAJA_00951 3.5e-183 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HILOHAJA_00952 2.5e-31 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HILOHAJA_00953 1.4e-89 ysxD
HILOHAJA_00954 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HILOHAJA_00955 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HILOHAJA_00956 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HILOHAJA_00957 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HILOHAJA_00958 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HILOHAJA_00959 2.3e-187 ysoA H Tetratricopeptide repeat
HILOHAJA_00960 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HILOHAJA_00961 6.3e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HILOHAJA_00962 9.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HILOHAJA_00963 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HILOHAJA_00964 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HILOHAJA_00965 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HILOHAJA_00966 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HILOHAJA_00968 7.6e-82 ysnE K acetyltransferase
HILOHAJA_00969 9.1e-134 ysnF S protein conserved in bacteria
HILOHAJA_00971 1.4e-92 ysnB S Phosphoesterase
HILOHAJA_00972 5e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HILOHAJA_00973 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HILOHAJA_00974 2.9e-196 gerM S COG5401 Spore germination protein
HILOHAJA_00975 2.1e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HILOHAJA_00976 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HILOHAJA_00977 3.3e-30 gerE K Transcriptional regulator
HILOHAJA_00978 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HILOHAJA_00979 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HILOHAJA_00980 2.4e-107 sdhC C succinate dehydrogenase
HILOHAJA_00981 1.2e-79 yslB S Protein of unknown function (DUF2507)
HILOHAJA_00982 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HILOHAJA_00983 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HILOHAJA_00984 2e-52 trxA O Belongs to the thioredoxin family
HILOHAJA_00985 4.1e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HILOHAJA_00987 2.1e-177 etfA C Electron transfer flavoprotein
HILOHAJA_00988 4.5e-135 etfB C Electron transfer flavoprotein
HILOHAJA_00989 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HILOHAJA_00990 2.7e-100 fadR K Transcriptional regulator
HILOHAJA_00991 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HILOHAJA_00992 7.3e-68 yshE S membrane
HILOHAJA_00993 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HILOHAJA_00994 0.0 polX L COG1796 DNA polymerase IV (family X)
HILOHAJA_00995 1.3e-85 cvpA S membrane protein, required for colicin V production
HILOHAJA_00996 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HILOHAJA_00997 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HILOHAJA_00998 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HILOHAJA_00999 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HILOHAJA_01000 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HILOHAJA_01001 2.6e-32 sspI S Belongs to the SspI family
HILOHAJA_01002 4.4e-208 ysfB KT regulator
HILOHAJA_01003 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
HILOHAJA_01004 5.6e-258 glcF C Glycolate oxidase
HILOHAJA_01005 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
HILOHAJA_01007 0.0 cstA T Carbon starvation protein
HILOHAJA_01008 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HILOHAJA_01009 3.8e-143 araQ G transport system permease
HILOHAJA_01010 1.4e-167 araP G carbohydrate transport
HILOHAJA_01011 4.9e-251 araN G carbohydrate transport
HILOHAJA_01012 4.4e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HILOHAJA_01013 3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HILOHAJA_01014 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HILOHAJA_01015 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HILOHAJA_01016 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HILOHAJA_01017 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HILOHAJA_01018 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HILOHAJA_01019 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HILOHAJA_01020 7.5e-45 ysdA S Membrane
HILOHAJA_01021 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HILOHAJA_01022 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HILOHAJA_01023 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HILOHAJA_01025 7.7e-110 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HILOHAJA_01026 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HILOHAJA_01027 5.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HILOHAJA_01028 0.0 lytS 2.7.13.3 T Histidine kinase
HILOHAJA_01029 2.8e-148 ysaA S HAD-hyrolase-like
HILOHAJA_01030 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HILOHAJA_01032 3.8e-159 ytxC S YtxC-like family
HILOHAJA_01033 4.9e-111 ytxB S SNARE associated Golgi protein
HILOHAJA_01034 3e-173 dnaI L Primosomal protein DnaI
HILOHAJA_01035 2.4e-133 dnaB L Membrane attachment protein
HILOHAJA_01036 5.1e-137 hemAT NT chemotaxis protein
HILOHAJA_01037 1.1e-90 bioY S BioY family
HILOHAJA_01038 1.8e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HILOHAJA_01039 1.4e-195 vraB 2.3.1.9 I Belongs to the thiolase family
HILOHAJA_01040 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HILOHAJA_01041 4.3e-159 yfmC M Periplasmic binding protein
HILOHAJA_01042 7e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
HILOHAJA_01043 7.3e-77 VY92_01935 K acetyltransferase
HILOHAJA_01044 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HILOHAJA_01045 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
HILOHAJA_01046 1.9e-65 yhfM
HILOHAJA_01047 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HILOHAJA_01048 2.6e-112 yhfK GM NmrA-like family
HILOHAJA_01049 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
HILOHAJA_01050 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HILOHAJA_01051 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HILOHAJA_01052 3.7e-72 3.4.13.21 S ASCH
HILOHAJA_01053 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HILOHAJA_01054 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
HILOHAJA_01055 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HILOHAJA_01056 1e-238 yhgE S YhgE Pip N-terminal domain protein
HILOHAJA_01057 2.4e-101 yhgD K Transcriptional regulator
HILOHAJA_01058 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HILOHAJA_01059 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HILOHAJA_01060 3.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HILOHAJA_01061 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HILOHAJA_01062 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HILOHAJA_01063 7.8e-33 1.15.1.2 C Rubrerythrin
HILOHAJA_01064 1.6e-231 yhfA C membrane
HILOHAJA_01065 2.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HILOHAJA_01066 3.4e-113 ecsC S EcsC protein family
HILOHAJA_01067 1.2e-214 ecsB U ABC transporter
HILOHAJA_01068 4.6e-137 ecsA V transporter (ATP-binding protein)
HILOHAJA_01069 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HILOHAJA_01070 1.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HILOHAJA_01071 3.6e-80 trpP S Tryptophan transporter TrpP
HILOHAJA_01072 5.4e-21
HILOHAJA_01073 7e-39 yhaH S YtxH-like protein
HILOHAJA_01074 1e-113 hpr K Negative regulator of protease production and sporulation
HILOHAJA_01075 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HILOHAJA_01076 8.7e-90 yhaK S Putative zincin peptidase
HILOHAJA_01077 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HILOHAJA_01078 1.6e-21 yhaL S Sporulation protein YhaL
HILOHAJA_01079 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HILOHAJA_01080 0.0 yhaN L AAA domain
HILOHAJA_01081 3.6e-227 yhaO L DNA repair exonuclease
HILOHAJA_01082 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HILOHAJA_01083 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HILOHAJA_01084 7e-26 S YhzD-like protein
HILOHAJA_01085 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HILOHAJA_01087 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HILOHAJA_01088 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HILOHAJA_01089 7.1e-294 hemZ H coproporphyrinogen III oxidase
HILOHAJA_01090 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HILOHAJA_01091 1.5e-205 yhaZ L DNA alkylation repair enzyme
HILOHAJA_01092 9.5e-48 yheA S Belongs to the UPF0342 family
HILOHAJA_01093 3.1e-201 yheB S Belongs to the UPF0754 family
HILOHAJA_01094 2.6e-213 yheC HJ YheC/D like ATP-grasp
HILOHAJA_01095 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HILOHAJA_01096 1.3e-36 yheE S Family of unknown function (DUF5342)
HILOHAJA_01097 6.3e-28 sspB S spore protein
HILOHAJA_01098 3.7e-111 yheG GM NAD(P)H-binding
HILOHAJA_01099 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HILOHAJA_01100 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HILOHAJA_01101 3.1e-84 nhaX T Belongs to the universal stress protein A family
HILOHAJA_01102 3.1e-232 nhaC C Na H antiporter
HILOHAJA_01103 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HILOHAJA_01104 1.7e-151 yheN G deacetylase
HILOHAJA_01105 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HILOHAJA_01106 6.6e-204 yhdY M Mechanosensitive ion channel
HILOHAJA_01108 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HILOHAJA_01109 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HILOHAJA_01110 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HILOHAJA_01111 2.1e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HILOHAJA_01112 1.7e-221 yhdR 2.6.1.1 E Aminotransferase
HILOHAJA_01113 4.1e-74 cueR K transcriptional
HILOHAJA_01114 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HILOHAJA_01115 6.7e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HILOHAJA_01116 2.6e-191 yhdN C Aldo keto reductase
HILOHAJA_01117 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HILOHAJA_01118 6.6e-201 yhdL S Sigma factor regulator N-terminal
HILOHAJA_01119 8.1e-45 yhdK S Sigma-M inhibitor protein
HILOHAJA_01120 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HILOHAJA_01121 3.3e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILOHAJA_01122 5.7e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HILOHAJA_01123 1.3e-249 yhdG E amino acid
HILOHAJA_01124 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILOHAJA_01125 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
HILOHAJA_01126 3.8e-162 citR K Transcriptional regulator
HILOHAJA_01127 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HILOHAJA_01128 2.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HILOHAJA_01129 2.1e-276 ycgB S Stage V sporulation protein R
HILOHAJA_01130 1.5e-238 ygxB M Conserved TM helix
HILOHAJA_01131 1e-75 nsrR K Transcriptional regulator
HILOHAJA_01132 1.4e-185 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HILOHAJA_01133 2e-52 yhdC S Protein of unknown function (DUF3889)
HILOHAJA_01134 1.2e-38 yhdB S YhdB-like protein
HILOHAJA_01135 3.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HILOHAJA_01136 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILOHAJA_01137 4e-212 yhcY 2.7.13.3 T Histidine kinase
HILOHAJA_01138 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HILOHAJA_01139 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HILOHAJA_01140 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HILOHAJA_01141 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HILOHAJA_01142 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HILOHAJA_01143 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HILOHAJA_01144 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HILOHAJA_01145 4.6e-120 yhcW 5.4.2.6 S hydrolase
HILOHAJA_01146 9.9e-68 yhcV S COG0517 FOG CBS domain
HILOHAJA_01147 2.1e-67 yhcU S Family of unknown function (DUF5365)
HILOHAJA_01148 3.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HILOHAJA_01149 4.2e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HILOHAJA_01150 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HILOHAJA_01151 5.2e-100 yhcQ M Spore coat protein
HILOHAJA_01152 1.2e-139 yhcP
HILOHAJA_01153 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HILOHAJA_01154 6.4e-41 yhcM
HILOHAJA_01155 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HILOHAJA_01156 3.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HILOHAJA_01157 2.8e-151 metQ M Belongs to the nlpA lipoprotein family
HILOHAJA_01158 1e-30 cspB K Cold-shock protein
HILOHAJA_01159 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HILOHAJA_01160 2.6e-166 yhcH V ABC transporter, ATP-binding protein
HILOHAJA_01161 1.6e-123 yhcG V ABC transporter, ATP-binding protein
HILOHAJA_01162 6.6e-60 yhcF K Transcriptional regulator
HILOHAJA_01163 7.8e-55
HILOHAJA_01164 2.8e-37 yhcC
HILOHAJA_01165 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HILOHAJA_01166 3.1e-271 yhcA EGP Major facilitator Superfamily
HILOHAJA_01167 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HILOHAJA_01168 2.2e-76 yhbI K DNA-binding transcription factor activity
HILOHAJA_01169 2.5e-225 yhbH S Belongs to the UPF0229 family
HILOHAJA_01170 0.0 prkA T Ser protein kinase
HILOHAJA_01171 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HILOHAJA_01172 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HILOHAJA_01173 1.2e-109 yhbD K Protein of unknown function (DUF4004)
HILOHAJA_01174 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HILOHAJA_01175 1.7e-176 yhbB S Putative amidase domain
HILOHAJA_01176 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HILOHAJA_01177 7.9e-114 yhzB S B3/4 domain
HILOHAJA_01179 4.4e-29 K Transcriptional regulator
HILOHAJA_01180 4.1e-78 ygaO
HILOHAJA_01181 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HILOHAJA_01183 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HILOHAJA_01184 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HILOHAJA_01185 1.7e-171 ssuA M Sulfonate ABC transporter
HILOHAJA_01186 3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HILOHAJA_01187 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HILOHAJA_01189 8.4e-262 ygaK C Berberine and berberine like
HILOHAJA_01190 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HILOHAJA_01191 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HILOHAJA_01192 3e-27
HILOHAJA_01193 7.4e-80 spo0M S COG4326 Sporulation control protein
HILOHAJA_01194 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HILOHAJA_01195 3.3e-71 ywhA K Transcriptional regulator
HILOHAJA_01196 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HILOHAJA_01197 5.1e-119 ywhC S Peptidase family M50
HILOHAJA_01198 2e-94 ywhD S YwhD family
HILOHAJA_01199 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HILOHAJA_01200 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HILOHAJA_01201 1.6e-168 speB 3.5.3.11 E Belongs to the arginase family
HILOHAJA_01202 3.7e-28 ywhH S Aminoacyl-tRNA editing domain
HILOHAJA_01204 8.9e-79 S aspartate phosphatase
HILOHAJA_01205 1e-190 ywhK CO amine dehydrogenase activity
HILOHAJA_01206 1.9e-245 ywhL CO amine dehydrogenase activity
HILOHAJA_01208 2.9e-248 L Peptidase, M16
HILOHAJA_01209 1.3e-213 2.7.1.26, 2.7.7.2 L Peptidase, M16
HILOHAJA_01210 6.5e-235 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HILOHAJA_01211 3.3e-132 cbiO V ABC transporter
HILOHAJA_01213 1.3e-270 C Fe-S oxidoreductases
HILOHAJA_01214 1e-07 S Bacteriocin subtilosin A
HILOHAJA_01215 4.7e-73 ywiB S protein conserved in bacteria
HILOHAJA_01216 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HILOHAJA_01217 9.8e-214 narK P COG2223 Nitrate nitrite transporter
HILOHAJA_01218 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
HILOHAJA_01219 1.7e-139 ywiC S YwiC-like protein
HILOHAJA_01220 7e-86 arfM T cyclic nucleotide binding
HILOHAJA_01221 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HILOHAJA_01222 9.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
HILOHAJA_01223 6.2e-94 narJ 1.7.5.1 C nitrate reductase
HILOHAJA_01224 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
HILOHAJA_01225 3.5e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HILOHAJA_01226 0.0 ywjA V ABC transporter
HILOHAJA_01227 2.6e-94 ywjB H RibD C-terminal domain
HILOHAJA_01228 2.7e-42 ywjC
HILOHAJA_01229 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HILOHAJA_01230 2.2e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HILOHAJA_01231 0.0 fadF C COG0247 Fe-S oxidoreductase
HILOHAJA_01232 1.8e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HILOHAJA_01233 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HILOHAJA_01234 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HILOHAJA_01235 6e-91 ywjG S Domain of unknown function (DUF2529)
HILOHAJA_01236 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HILOHAJA_01237 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HILOHAJA_01238 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HILOHAJA_01239 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HILOHAJA_01240 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HILOHAJA_01241 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HILOHAJA_01242 1.1e-32 rpmE J Binds the 23S rRNA
HILOHAJA_01243 7e-104 tdk 2.7.1.21 F thymidine kinase
HILOHAJA_01244 0.0 sfcA 1.1.1.38 C malic enzyme
HILOHAJA_01245 8.6e-160 ywkB S Membrane transport protein
HILOHAJA_01246 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HILOHAJA_01247 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILOHAJA_01248 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HILOHAJA_01249 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HILOHAJA_01251 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
HILOHAJA_01252 6.1e-112 spoIIR S stage II sporulation protein R
HILOHAJA_01253 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HILOHAJA_01254 1.3e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HILOHAJA_01255 1.7e-91 mntP P Probably functions as a manganese efflux pump
HILOHAJA_01256 6.2e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HILOHAJA_01257 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HILOHAJA_01258 7.2e-95 ywlG S Belongs to the UPF0340 family
HILOHAJA_01259 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HILOHAJA_01260 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HILOHAJA_01261 2.5e-62 atpI S ATP synthase
HILOHAJA_01262 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HILOHAJA_01263 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HILOHAJA_01264 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HILOHAJA_01265 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HILOHAJA_01266 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HILOHAJA_01267 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HILOHAJA_01268 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HILOHAJA_01269 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HILOHAJA_01270 1.8e-86 ywmA
HILOHAJA_01271 2.1e-32 ywzB S membrane
HILOHAJA_01272 2.4e-133 ywmB S TATA-box binding
HILOHAJA_01273 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HILOHAJA_01274 3.9e-174 spoIID D Stage II sporulation protein D
HILOHAJA_01275 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HILOHAJA_01276 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HILOHAJA_01278 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HILOHAJA_01279 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HILOHAJA_01280 1.3e-103 S response regulator aspartate phosphatase
HILOHAJA_01281 3e-84 ywmF S Peptidase M50
HILOHAJA_01282 3.8e-11 csbD K CsbD-like
HILOHAJA_01283 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HILOHAJA_01284 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HILOHAJA_01285 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HILOHAJA_01286 1.7e-64 ywnA K Transcriptional regulator
HILOHAJA_01287 3.1e-113 ywnB S NAD(P)H-binding
HILOHAJA_01288 1.7e-58 ywnC S Family of unknown function (DUF5362)
HILOHAJA_01289 5.3e-144 mta K transcriptional
HILOHAJA_01290 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HILOHAJA_01291 2.9e-70 ywnF S Family of unknown function (DUF5392)
HILOHAJA_01292 9.8e-09 ywnC S Family of unknown function (DUF5362)
HILOHAJA_01293 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HILOHAJA_01294 2e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HILOHAJA_01295 3.5e-73 ywnJ S VanZ like family
HILOHAJA_01296 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HILOHAJA_01297 1.6e-58 nrgB K Belongs to the P(II) protein family
HILOHAJA_01298 4.3e-225 amt P Ammonium transporter
HILOHAJA_01299 1.2e-77
HILOHAJA_01300 6.8e-104 phzA Q Isochorismatase family
HILOHAJA_01301 4.8e-241 ywoD EGP Major facilitator superfamily
HILOHAJA_01302 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HILOHAJA_01303 1.2e-231 ywoF P Right handed beta helix region
HILOHAJA_01304 2.7e-211 ywoG EGP Major facilitator Superfamily
HILOHAJA_01305 2.1e-70 ywoH K COG1846 Transcriptional regulators
HILOHAJA_01306 3e-44 spoIIID K Stage III sporulation protein D
HILOHAJA_01307 3.5e-180 mbl D Rod shape-determining protein
HILOHAJA_01308 2.2e-124 flhO N flagellar basal body
HILOHAJA_01309 5.8e-141 flhP N flagellar basal body
HILOHAJA_01310 2.3e-198 S aspartate phosphatase
HILOHAJA_01311 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HILOHAJA_01312 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HILOHAJA_01313 0.0 ywpD T PhoQ Sensor
HILOHAJA_01314 9e-174 M1-574 T Transcriptional regulatory protein, C terminal
HILOHAJA_01315 0.0 M1-568 M cell wall anchor domain
HILOHAJA_01316 1.8e-84 srtA 3.4.22.70 M Sortase family
HILOHAJA_01317 1.1e-66 ywpF S YwpF-like protein
HILOHAJA_01318 1.3e-66 ywpG
HILOHAJA_01319 3.7e-57 ssbB L Single-stranded DNA-binding protein
HILOHAJA_01320 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HILOHAJA_01321 7.4e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HILOHAJA_01322 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HILOHAJA_01323 6e-307 ywqB S SWIM zinc finger
HILOHAJA_01324 1.2e-17
HILOHAJA_01325 2e-116 ywqC M biosynthesis protein
HILOHAJA_01326 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HILOHAJA_01327 1.9e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HILOHAJA_01328 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HILOHAJA_01329 1.3e-63 ywqG S Domain of unknown function (DUF1963)
HILOHAJA_01330 4.4e-51 ywqG S Domain of unknown function (DUF1963)
HILOHAJA_01331 9.7e-23 S Domain of unknown function (DUF5082)
HILOHAJA_01332 3.9e-38 ywqI S Family of unknown function (DUF5344)
HILOHAJA_01333 2.3e-241 ywqJ S Pre-toxin TG
HILOHAJA_01334 3.9e-25
HILOHAJA_01335 3.9e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HILOHAJA_01336 3.2e-161 K Transcriptional regulator
HILOHAJA_01337 2.9e-96 ywqN S NAD(P)H-dependent
HILOHAJA_01339 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
HILOHAJA_01340 2.1e-103 ywrB P Chromate transporter
HILOHAJA_01341 8e-82 ywrC K Transcriptional regulator
HILOHAJA_01342 1e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HILOHAJA_01343 1.5e-50 S Domain of unknown function (DUF4181)
HILOHAJA_01344 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HILOHAJA_01345 3.7e-12
HILOHAJA_01346 3.5e-210 cotH M Spore Coat
HILOHAJA_01347 7.6e-131 cotB
HILOHAJA_01348 9.2e-124 ywrJ
HILOHAJA_01349 5.5e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HILOHAJA_01350 2.5e-169 alsR K LysR substrate binding domain
HILOHAJA_01351 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HILOHAJA_01352 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HILOHAJA_01353 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HILOHAJA_01354 3.6e-48 ywsA S Protein of unknown function (DUF3892)
HILOHAJA_01355 4.6e-94 batE T Sh3 type 3 domain protein
HILOHAJA_01356 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HILOHAJA_01357 4.6e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
HILOHAJA_01358 4.7e-274 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HILOHAJA_01359 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HILOHAJA_01360 1.6e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HILOHAJA_01361 5.5e-178 rbsR K transcriptional
HILOHAJA_01362 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HILOHAJA_01363 8.6e-70 pgsC S biosynthesis protein
HILOHAJA_01364 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HILOHAJA_01365 1.4e-20 ywtC
HILOHAJA_01366 4.5e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HILOHAJA_01367 2.9e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HILOHAJA_01368 4.2e-170 ywtF K Transcriptional regulator
HILOHAJA_01369 1.9e-248 ywtG EGP Major facilitator Superfamily
HILOHAJA_01370 3.8e-215 gerAC S Spore germination protein
HILOHAJA_01371 7.5e-200 gerBB E Spore germination protein
HILOHAJA_01372 3.5e-266 gerBA EG Spore germination protein
HILOHAJA_01373 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HILOHAJA_01374 2.8e-216 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HILOHAJA_01375 3.5e-260
HILOHAJA_01376 1.5e-214 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HILOHAJA_01377 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HILOHAJA_01378 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HILOHAJA_01379 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HILOHAJA_01380 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HILOHAJA_01381 1.1e-150 tagG GM Transport permease protein
HILOHAJA_01382 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HILOHAJA_01383 3.4e-77 IQ Enoyl-(Acyl carrier protein) reductase
HILOHAJA_01384 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HILOHAJA_01385 1.9e-209 bacE EGP Major facilitator Superfamily
HILOHAJA_01386 4.7e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HILOHAJA_01387 4.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILOHAJA_01388 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HILOHAJA_01389 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HILOHAJA_01390 1.5e-204 ywfA EGP Major facilitator Superfamily
HILOHAJA_01391 4.8e-249 lysP E amino acid
HILOHAJA_01392 0.0 rocB E arginine degradation protein
HILOHAJA_01393 3.5e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HILOHAJA_01394 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HILOHAJA_01395 1.2e-77
HILOHAJA_01396 1.3e-86 spsL 5.1.3.13 M Spore Coat
HILOHAJA_01397 4.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HILOHAJA_01398 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HILOHAJA_01399 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HILOHAJA_01400 6.3e-185 spsG M Spore Coat
HILOHAJA_01401 3.5e-129 spsF M Spore Coat
HILOHAJA_01402 3.5e-213 spsE 2.5.1.56 M acid synthase
HILOHAJA_01403 5.8e-163 spsD 2.3.1.210 K Spore Coat
HILOHAJA_01404 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
HILOHAJA_01405 6.1e-268 spsB M Capsule polysaccharide biosynthesis protein
HILOHAJA_01406 6.9e-144 spsA M Spore Coat
HILOHAJA_01407 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HILOHAJA_01408 4.3e-59 ywdK S small membrane protein
HILOHAJA_01409 3.7e-238 ywdJ F Xanthine uracil
HILOHAJA_01410 1.7e-48 ywdI S Family of unknown function (DUF5327)
HILOHAJA_01411 3.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HILOHAJA_01412 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HILOHAJA_01413 1e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
HILOHAJA_01414 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HILOHAJA_01415 2e-28 ywdA
HILOHAJA_01416 9.8e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HILOHAJA_01417 7.6e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILOHAJA_01418 1e-139 focA P Formate/nitrite transporter
HILOHAJA_01419 7e-150 sacT K transcriptional antiterminator
HILOHAJA_01421 0.0 vpr O Belongs to the peptidase S8 family
HILOHAJA_01422 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HILOHAJA_01423 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HILOHAJA_01424 8.6e-202 rodA D Belongs to the SEDS family
HILOHAJA_01425 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HILOHAJA_01426 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HILOHAJA_01427 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HILOHAJA_01428 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HILOHAJA_01429 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HILOHAJA_01430 1e-35 ywzA S membrane
HILOHAJA_01431 4e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HILOHAJA_01432 8.4e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HILOHAJA_01433 9.5e-60 gtcA S GtrA-like protein
HILOHAJA_01434 2.2e-122 ywcC K transcriptional regulator
HILOHAJA_01436 2.9e-48 ywcB S Protein of unknown function, DUF485
HILOHAJA_01437 6.9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HILOHAJA_01438 9e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HILOHAJA_01439 1.9e-223 ywbN P Dyp-type peroxidase family protein
HILOHAJA_01440 9.3e-185 ycdO P periplasmic lipoprotein involved in iron transport
HILOHAJA_01441 3.4e-253 P COG0672 High-affinity Fe2 Pb2 permease
HILOHAJA_01442 1.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HILOHAJA_01443 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HILOHAJA_01444 4.3e-153 ywbI K Transcriptional regulator
HILOHAJA_01445 2.2e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HILOHAJA_01446 5.2e-111 ywbG M effector of murein hydrolase
HILOHAJA_01447 3.1e-207 ywbF EGP Major facilitator Superfamily
HILOHAJA_01448 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HILOHAJA_01449 1.2e-219 ywbD 2.1.1.191 J Methyltransferase
HILOHAJA_01450 2.2e-66 ywbC 4.4.1.5 E glyoxalase
HILOHAJA_01451 9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HILOHAJA_01452 8.4e-63 ywbB S Protein of unknown function (DUF2711)
HILOHAJA_01453 2.1e-43 ywbB S Protein of unknown function (DUF2711)
HILOHAJA_01454 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HILOHAJA_01455 6.4e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
HILOHAJA_01456 5.8e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILOHAJA_01457 1.2e-152 sacY K transcriptional antiterminator
HILOHAJA_01458 2.9e-167 gspA M General stress
HILOHAJA_01459 1.6e-123 ywaF S Integral membrane protein
HILOHAJA_01460 3.4e-86 ywaE K Transcriptional regulator
HILOHAJA_01461 2.4e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HILOHAJA_01462 5.2e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HILOHAJA_01463 1.4e-92 K Helix-turn-helix XRE-family like proteins
HILOHAJA_01464 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
HILOHAJA_01465 1e-130 ynfM EGP Major facilitator Superfamily
HILOHAJA_01466 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HILOHAJA_01467 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HILOHAJA_01468 5e-14 S D-Ala-teichoic acid biosynthesis protein
HILOHAJA_01469 1.1e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILOHAJA_01470 4.7e-232 dltB M membrane protein involved in D-alanine export
HILOHAJA_01471 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILOHAJA_01472 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HILOHAJA_01473 4.4e-135 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HILOHAJA_01474 9e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HILOHAJA_01475 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HILOHAJA_01476 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HILOHAJA_01477 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HILOHAJA_01478 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HILOHAJA_01479 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HILOHAJA_01480 1.1e-19 yxzF
HILOHAJA_01481 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HILOHAJA_01482 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HILOHAJA_01483 9.3e-212 yxlH EGP Major facilitator Superfamily
HILOHAJA_01484 7e-136 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HILOHAJA_01485 4.8e-165 yxlF V ABC transporter, ATP-binding protein
HILOHAJA_01486 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HILOHAJA_01487 1.2e-31
HILOHAJA_01488 3.9e-48 yxlC S Family of unknown function (DUF5345)
HILOHAJA_01489 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HILOHAJA_01490 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HILOHAJA_01491 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HILOHAJA_01492 0.0 cydD V ATP-binding protein
HILOHAJA_01493 2.1e-310 cydD V ATP-binding
HILOHAJA_01494 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HILOHAJA_01495 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
HILOHAJA_01496 2.1e-228 cimH C COG3493 Na citrate symporter
HILOHAJA_01497 2.8e-310 3.4.24.84 O Peptidase family M48
HILOHAJA_01499 7.3e-155 yxkH G Polysaccharide deacetylase
HILOHAJA_01500 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HILOHAJA_01501 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HILOHAJA_01502 6.3e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HILOHAJA_01503 7.3e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HILOHAJA_01504 1.5e-137
HILOHAJA_01505 5.7e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HILOHAJA_01506 6.9e-78 S Protein of unknown function (DUF1453)
HILOHAJA_01507 1.6e-190 yxjM T Signal transduction histidine kinase
HILOHAJA_01508 4.9e-114 K helix_turn_helix, Lux Regulon
HILOHAJA_01509 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HILOHAJA_01512 1.6e-85 yxjI S LURP-one-related
HILOHAJA_01513 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
HILOHAJA_01514 2.8e-218 yxjG 2.1.1.14 E Methionine synthase
HILOHAJA_01515 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HILOHAJA_01516 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HILOHAJA_01517 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HILOHAJA_01518 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HILOHAJA_01519 1.6e-157 rlmA 2.1.1.187 Q Methyltransferase domain
HILOHAJA_01520 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HILOHAJA_01521 7.2e-89 T Domain of unknown function (DUF4163)
HILOHAJA_01522 3e-47 yxiS
HILOHAJA_01523 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HILOHAJA_01524 6.6e-224 citH C Citrate transporter
HILOHAJA_01525 2.1e-142 exoK GH16 M licheninase activity
HILOHAJA_01526 8.3e-151 licT K transcriptional antiterminator
HILOHAJA_01527 1.2e-110
HILOHAJA_01528 3.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
HILOHAJA_01529 1.9e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HILOHAJA_01530 1.4e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HILOHAJA_01533 3.3e-41 yxiJ S YxiJ-like protein
HILOHAJA_01534 2.1e-85 yxiI S Protein of unknown function (DUF2716)
HILOHAJA_01535 2.2e-135
HILOHAJA_01536 3.7e-75 yxiG
HILOHAJA_01537 6.4e-63
HILOHAJA_01538 1.7e-84
HILOHAJA_01539 1.5e-71 yxxG
HILOHAJA_01540 0.0 wapA M COG3209 Rhs family protein
HILOHAJA_01541 2.9e-168 yxxF EG EamA-like transporter family
HILOHAJA_01542 1.1e-72 yxiE T Belongs to the universal stress protein A family
HILOHAJA_01543 1.4e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HILOHAJA_01544 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILOHAJA_01545 3.6e-51
HILOHAJA_01546 2.2e-78 S SMI1 / KNR4 family
HILOHAJA_01547 0.0 S nuclease activity
HILOHAJA_01548 4.7e-39 yxiC S Family of unknown function (DUF5344)
HILOHAJA_01549 1.8e-17 S Domain of unknown function (DUF5082)
HILOHAJA_01550 2.6e-282 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HILOHAJA_01551 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HILOHAJA_01552 1.3e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
HILOHAJA_01553 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HILOHAJA_01554 4.1e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HILOHAJA_01555 3e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HILOHAJA_01556 2.3e-251 lysP E amino acid
HILOHAJA_01557 1e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HILOHAJA_01558 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HILOHAJA_01559 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HILOHAJA_01560 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HILOHAJA_01561 4.4e-152 yxxB S Domain of Unknown Function (DUF1206)
HILOHAJA_01562 4.6e-197 eutH E Ethanolamine utilisation protein, EutH
HILOHAJA_01563 2.6e-247 yxeQ S MmgE/PrpD family
HILOHAJA_01564 2.3e-212 yxeP 3.5.1.47 E hydrolase activity
HILOHAJA_01565 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HILOHAJA_01566 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
HILOHAJA_01567 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HILOHAJA_01568 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HILOHAJA_01569 4.9e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HILOHAJA_01570 1.1e-186 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HILOHAJA_01571 5.2e-150 yidA S hydrolases of the HAD superfamily
HILOHAJA_01574 1.3e-20 yxeE
HILOHAJA_01575 1.9e-16 yxeD
HILOHAJA_01576 8.5e-69
HILOHAJA_01577 1.7e-176 fhuD P ABC transporter
HILOHAJA_01578 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HILOHAJA_01579 0.0 yxdM V ABC transporter (permease)
HILOHAJA_01580 1.4e-139 yxdL V ABC transporter, ATP-binding protein
HILOHAJA_01581 1.3e-182 T PhoQ Sensor
HILOHAJA_01582 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILOHAJA_01583 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HILOHAJA_01584 1.2e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HILOHAJA_01585 8.6e-167 iolH G Xylose isomerase-like TIM barrel
HILOHAJA_01586 1.4e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HILOHAJA_01587 3e-235 iolF EGP Major facilitator Superfamily
HILOHAJA_01588 1.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HILOHAJA_01589 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HILOHAJA_01590 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HILOHAJA_01591 2.1e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HILOHAJA_01592 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HILOHAJA_01593 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HILOHAJA_01594 3.7e-176 iolS C Aldo keto reductase
HILOHAJA_01596 1.7e-93 M Glycosyltransferase like family
HILOHAJA_01597 3.8e-120 H Methionine biosynthesis protein MetW
HILOHAJA_01598 3e-196 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HILOHAJA_01599 7.9e-215 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
HILOHAJA_01601 2.6e-187 S aspartate phosphatase
HILOHAJA_01602 4e-98 ynaD J Acetyltransferase (GNAT) domain
HILOHAJA_01603 3.3e-76 S CAAX protease self-immunity
HILOHAJA_01604 4.7e-08 S Uncharacterised protein family (UPF0715)
HILOHAJA_01606 5.5e-20 K Cro/C1-type HTH DNA-binding domain
HILOHAJA_01607 1.1e-110 ynaE S Domain of unknown function (DUF3885)
HILOHAJA_01610 3.9e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HILOHAJA_01611 8.7e-254 xynT G MFS/sugar transport protein
HILOHAJA_01612 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HILOHAJA_01613 4e-212 xylR GK ROK family
HILOHAJA_01614 2.2e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HILOHAJA_01615 1.2e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HILOHAJA_01616 1.3e-111 yokF 3.1.31.1 L RNA catabolic process
HILOHAJA_01617 4.7e-255 iolT EGP Major facilitator Superfamily
HILOHAJA_01618 9.8e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HILOHAJA_01619 1.3e-81 yncE S Protein of unknown function (DUF2691)
HILOHAJA_01620 7e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HILOHAJA_01621 5.2e-15
HILOHAJA_01624 8.6e-164 S Thymidylate synthase
HILOHAJA_01626 3.7e-134 S Domain of unknown function, YrpD
HILOHAJA_01629 7.9e-25 tatA U protein secretion
HILOHAJA_01630 1.8e-71
HILOHAJA_01631 1.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HILOHAJA_01634 2.2e-285 gerAA EG Spore germination protein
HILOHAJA_01635 1.7e-196 gerAB U Spore germination
HILOHAJA_01636 4.2e-220 gerLC S Spore germination protein
HILOHAJA_01637 5.5e-152 yndG S DoxX-like family
HILOHAJA_01638 3.2e-115 yndH S Domain of unknown function (DUF4166)
HILOHAJA_01639 0.0 yndJ S YndJ-like protein
HILOHAJA_01641 4.7e-137 yndL S Replication protein
HILOHAJA_01642 5.8e-74 yndM S Protein of unknown function (DUF2512)
HILOHAJA_01643 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HILOHAJA_01644 9.9e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HILOHAJA_01645 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HILOHAJA_01646 4.5e-112 yneB L resolvase
HILOHAJA_01647 3.7e-32 ynzC S UPF0291 protein
HILOHAJA_01648 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HILOHAJA_01649 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HILOHAJA_01650 1.8e-28 yneF S UPF0154 protein
HILOHAJA_01651 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HILOHAJA_01652 7.1e-127 ccdA O cytochrome c biogenesis protein
HILOHAJA_01653 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HILOHAJA_01654 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HILOHAJA_01655 4.2e-74 yneK S Protein of unknown function (DUF2621)
HILOHAJA_01656 4.1e-65 hspX O Spore coat protein
HILOHAJA_01657 3.9e-19 sspP S Belongs to the SspP family
HILOHAJA_01658 1.1e-13 sspO S Belongs to the SspO family
HILOHAJA_01659 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HILOHAJA_01660 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HILOHAJA_01662 3.1e-08 sspN S Small acid-soluble spore protein N family
HILOHAJA_01663 3.9e-35 tlp S Belongs to the Tlp family
HILOHAJA_01664 1.2e-73 yneP S Thioesterase-like superfamily
HILOHAJA_01665 1.3e-53 yneQ
HILOHAJA_01666 4.1e-49 yneR S Belongs to the HesB IscA family
HILOHAJA_01667 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HILOHAJA_01668 6.6e-69 yccU S CoA-binding protein
HILOHAJA_01669 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HILOHAJA_01670 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HILOHAJA_01671 2.3e-12
HILOHAJA_01672 1.3e-57 ynfC
HILOHAJA_01673 8.2e-252 agcS E Sodium alanine symporter
HILOHAJA_01674 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HILOHAJA_01676 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HILOHAJA_01677 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HILOHAJA_01678 2.4e-80 yngA S membrane
HILOHAJA_01679 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HILOHAJA_01680 5.5e-104 yngC S membrane-associated protein
HILOHAJA_01681 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
HILOHAJA_01682 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HILOHAJA_01683 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HILOHAJA_01684 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HILOHAJA_01685 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HILOHAJA_01686 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HILOHAJA_01687 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HILOHAJA_01688 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HILOHAJA_01689 1.8e-31 S Family of unknown function (DUF5367)
HILOHAJA_01690 1.3e-306 yngK T Glycosyl hydrolase-like 10
HILOHAJA_01691 2.8e-64 yngL S Protein of unknown function (DUF1360)
HILOHAJA_01692 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HILOHAJA_01693 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILOHAJA_01694 3e-113 yodN
HILOHAJA_01696 2.8e-24 yozD S YozD-like protein
HILOHAJA_01697 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
HILOHAJA_01698 3.6e-54 yodL S YodL-like
HILOHAJA_01699 5.3e-09
HILOHAJA_01700 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HILOHAJA_01701 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HILOHAJA_01702 5.2e-24 yodI
HILOHAJA_01703 1.7e-128 yodH Q Methyltransferase
HILOHAJA_01704 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HILOHAJA_01705 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HILOHAJA_01706 6.2e-28 S Protein of unknown function (DUF3311)
HILOHAJA_01707 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
HILOHAJA_01708 3.8e-113 mhqD S Carboxylesterase
HILOHAJA_01709 4.8e-108 yodC C nitroreductase
HILOHAJA_01710 1.7e-57 yodB K transcriptional
HILOHAJA_01711 3.8e-66 yodA S tautomerase
HILOHAJA_01712 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
HILOHAJA_01713 3.4e-09
HILOHAJA_01714 3.7e-63 yozR S COG0071 Molecular chaperone (small heat shock protein)
HILOHAJA_01715 6.6e-162 rarD S -transporter
HILOHAJA_01716 1.5e-43
HILOHAJA_01717 2.2e-60 yojF S Protein of unknown function (DUF1806)
HILOHAJA_01718 2.1e-125 yojG S deacetylase
HILOHAJA_01719 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HILOHAJA_01720 4.2e-245 norM V Multidrug efflux pump
HILOHAJA_01722 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HILOHAJA_01723 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HILOHAJA_01724 4.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HILOHAJA_01725 1.5e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HILOHAJA_01726 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
HILOHAJA_01727 0.0 yojO P Von Willebrand factor
HILOHAJA_01728 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HILOHAJA_01729 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HILOHAJA_01730 5.1e-168 yocS S -transporter
HILOHAJA_01731 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HILOHAJA_01732 6e-165 sodA 1.15.1.1 P Superoxide dismutase
HILOHAJA_01733 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HILOHAJA_01734 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HILOHAJA_01735 2.7e-31 yozC
HILOHAJA_01736 4.2e-56 yozO S Bacterial PH domain
HILOHAJA_01737 1.9e-36 yocN
HILOHAJA_01738 1.1e-40 yozN
HILOHAJA_01739 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HILOHAJA_01740 6.6e-34
HILOHAJA_01741 6.4e-54 yocL
HILOHAJA_01742 3.3e-83 dksA T general stress protein
HILOHAJA_01743 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HILOHAJA_01744 0.0 recQ 3.6.4.12 L DNA helicase
HILOHAJA_01745 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HILOHAJA_01746 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILOHAJA_01747 7.1e-198 desK 2.7.13.3 T Histidine kinase
HILOHAJA_01748 3.4e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HILOHAJA_01749 6.4e-187 yocD 3.4.17.13 V peptidase S66
HILOHAJA_01750 1.6e-93 yocC
HILOHAJA_01751 8.6e-142
HILOHAJA_01752 4.3e-92 yozB S membrane
HILOHAJA_01753 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HILOHAJA_01754 1e-51 czrA K transcriptional
HILOHAJA_01755 6.1e-94 yobW
HILOHAJA_01756 3.2e-175 yobV K WYL domain
HILOHAJA_01757 3.4e-88 yobU K Bacterial transcription activator, effector binding domain
HILOHAJA_01758 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HILOHAJA_01759 3.3e-98 yobS K Transcriptional regulator
HILOHAJA_01760 4.5e-140 yobR 2.3.1.1 J FR47-like protein
HILOHAJA_01761 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
HILOHAJA_01762 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HILOHAJA_01763 0.0 yobO M Pectate lyase superfamily protein
HILOHAJA_01764 1.1e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HILOHAJA_01765 1.7e-91 yokH G SMI1 / KNR4 family
HILOHAJA_01766 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HILOHAJA_01767 3.3e-85 S SMI1-KNR4 cell-wall
HILOHAJA_01768 6.5e-107 ypbG 2.7.1.2 GK ROK family
HILOHAJA_01769 0.0 rafA 3.2.1.22 G Alpha-galactosidase
HILOHAJA_01770 6.8e-103 G Binding-protein-dependent transport system inner membrane component
HILOHAJA_01771 1.3e-101 P COG0395 ABC-type sugar transport system, permease component
HILOHAJA_01772 6.2e-91 G Bacterial extracellular solute-binding protein
HILOHAJA_01774 2.1e-215 3.2.1.86 GT1 G Glycosyl hydrolase family 1
HILOHAJA_01775 5.2e-131 purR15 K Bacterial regulatory proteins, lacI family
HILOHAJA_01776 4.7e-179 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HILOHAJA_01777 2.6e-22 yoqW S Belongs to the SOS response-associated peptidase family
HILOHAJA_01778 6.8e-65 yoaQ S Evidence 4 Homologs of previously reported genes of
HILOHAJA_01780 1.9e-07 K Helix-turn-helix
HILOHAJA_01781 8.8e-37 S TM2 domain
HILOHAJA_01782 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HILOHAJA_01783 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HILOHAJA_01787 5.9e-166 bla 3.5.2.6 V beta-lactamase
HILOHAJA_01788 1.3e-116 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HILOHAJA_01789 1.8e-77 yoaW
HILOHAJA_01790 1.5e-158 yijE EG EamA-like transporter family
HILOHAJA_01791 4.3e-158 yoaU K LysR substrate binding domain
HILOHAJA_01792 1.4e-147 yoaT S Protein of unknown function (DUF817)
HILOHAJA_01793 4.2e-37 yozG K Transcriptional regulator
HILOHAJA_01794 4.3e-75 yoaS S Protein of unknown function (DUF2975)
HILOHAJA_01795 2.4e-172 yoaR V vancomycin resistance protein
HILOHAJA_01796 4.1e-89
HILOHAJA_01797 2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
HILOHAJA_01798 1.9e-146 yoaP 3.1.3.18 K YoaP-like
HILOHAJA_01800 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
HILOHAJA_01802 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
HILOHAJA_01803 7.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HILOHAJA_01804 2.3e-111 yoaK S Membrane
HILOHAJA_01805 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HILOHAJA_01806 6.2e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HILOHAJA_01807 4.7e-185 mcpU NT methyl-accepting chemotaxis protein
HILOHAJA_01808 7.4e-38 S Protein of unknown function (DUF4025)
HILOHAJA_01809 2.6e-13
HILOHAJA_01810 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
HILOHAJA_01811 5.3e-36 yoaF
HILOHAJA_01812 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HILOHAJA_01813 5.2e-184 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HILOHAJA_01814 2e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HILOHAJA_01815 9.9e-233 yoaB EGP Major facilitator Superfamily
HILOHAJA_01816 1.9e-126 3.1.1.3 I Lipase (class 3)
HILOHAJA_01817 1.8e-240 S Arylsulfotransferase (ASST)
HILOHAJA_01818 1.9e-84 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HILOHAJA_01819 2.4e-128 yoxB
HILOHAJA_01820 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
HILOHAJA_01821 1e-120 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HILOHAJA_01822 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HILOHAJA_01823 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HILOHAJA_01824 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HILOHAJA_01825 7.8e-155 gltC K Transcriptional regulator
HILOHAJA_01826 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HILOHAJA_01827 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HILOHAJA_01828 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HILOHAJA_01829 2.5e-158 gltR1 K Transcriptional regulator
HILOHAJA_01830 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HILOHAJA_01831 3e-34 yoeD G Helix-turn-helix domain
HILOHAJA_01832 2.2e-96 L Integrase
HILOHAJA_01834 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HILOHAJA_01835 2.3e-246 yoeA V MATE efflux family protein
HILOHAJA_01836 5.8e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
HILOHAJA_01837 4.9e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HILOHAJA_01838 3.4e-31 csfB S Inhibitor of sigma-G Gin
HILOHAJA_01839 6.8e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HILOHAJA_01840 2.9e-202 yaaN P Belongs to the TelA family
HILOHAJA_01841 3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HILOHAJA_01842 2.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HILOHAJA_01843 2.2e-54 yaaQ S protein conserved in bacteria
HILOHAJA_01844 1.5e-71 yaaR S protein conserved in bacteria
HILOHAJA_01845 2.2e-182 holB 2.7.7.7 L DNA polymerase III
HILOHAJA_01846 6.1e-146 yaaT S stage 0 sporulation protein
HILOHAJA_01847 4.8e-31 yabA L Involved in initiation control of chromosome replication
HILOHAJA_01848 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HILOHAJA_01849 2.8e-48 yazA L endonuclease containing a URI domain
HILOHAJA_01850 1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HILOHAJA_01851 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HILOHAJA_01852 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HILOHAJA_01853 1.2e-143 tatD L hydrolase, TatD
HILOHAJA_01854 4.3e-194 rpfB GH23 T protein conserved in bacteria
HILOHAJA_01855 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HILOHAJA_01856 6.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HILOHAJA_01857 1.8e-135 yabG S peptidase
HILOHAJA_01858 7.8e-39 veg S protein conserved in bacteria
HILOHAJA_01859 8.3e-27 sspF S DNA topological change
HILOHAJA_01860 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HILOHAJA_01861 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HILOHAJA_01862 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HILOHAJA_01863 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HILOHAJA_01864 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HILOHAJA_01865 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HILOHAJA_01866 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HILOHAJA_01867 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HILOHAJA_01868 2.4e-39 yabK S Peptide ABC transporter permease
HILOHAJA_01869 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HILOHAJA_01870 1.5e-92 spoVT K stage V sporulation protein
HILOHAJA_01871 1.3e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HILOHAJA_01872 1.9e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HILOHAJA_01873 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HILOHAJA_01874 1.5e-49 yabP S Sporulation protein YabP
HILOHAJA_01875 4.3e-107 yabQ S spore cortex biosynthesis protein
HILOHAJA_01876 1.1e-44 divIC D Septum formation initiator
HILOHAJA_01877 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HILOHAJA_01880 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HILOHAJA_01881 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HILOHAJA_01882 1.1e-184 KLT serine threonine protein kinase
HILOHAJA_01883 6.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HILOHAJA_01884 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HILOHAJA_01885 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HILOHAJA_01886 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HILOHAJA_01887 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HILOHAJA_01888 7.7e-152 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HILOHAJA_01889 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HILOHAJA_01890 6.1e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HILOHAJA_01891 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HILOHAJA_01892 1.3e-165 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HILOHAJA_01893 1.7e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HILOHAJA_01894 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HILOHAJA_01895 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HILOHAJA_01896 4.1e-30 yazB K transcriptional
HILOHAJA_01897 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HILOHAJA_01898 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HILOHAJA_01899 1.1e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HILOHAJA_01900 3.8e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HILOHAJA_01901 2.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HILOHAJA_01902 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HILOHAJA_01903 1.1e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HILOHAJA_01904 0.0 ydiF S ABC transporter
HILOHAJA_01905 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HILOHAJA_01906 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HILOHAJA_01907 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HILOHAJA_01908 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HILOHAJA_01909 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HILOHAJA_01910 7.9e-129 ydiL S CAAX protease self-immunity
HILOHAJA_01911 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HILOHAJA_01912 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HILOHAJA_01913 0.0 K NB-ARC domain
HILOHAJA_01914 2.7e-199 gutB 1.1.1.14 E Dehydrogenase
HILOHAJA_01915 6.2e-252 gutA G MFS/sugar transport protein
HILOHAJA_01916 6.4e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HILOHAJA_01917 5.6e-113 pspA KT Phage shock protein A
HILOHAJA_01918 1.1e-176 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HILOHAJA_01919 3.4e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HILOHAJA_01920 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
HILOHAJA_01921 2.3e-195 S Ion transport 2 domain protein
HILOHAJA_01922 2.1e-255 iolT EGP Major facilitator Superfamily
HILOHAJA_01923 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HILOHAJA_01924 2.9e-63 ydjM M Lytic transglycolase
HILOHAJA_01925 8e-151 ydjN U Involved in the tonB-independent uptake of proteins
HILOHAJA_01927 1.4e-34 ydjO S Cold-inducible protein YdjO
HILOHAJA_01928 3.8e-156 ydjP I Alpha/beta hydrolase family
HILOHAJA_01929 3.3e-175 yeaA S Protein of unknown function (DUF4003)
HILOHAJA_01930 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HILOHAJA_01931 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HILOHAJA_01932 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HILOHAJA_01933 1.7e-176 yeaC S COG0714 MoxR-like ATPases
HILOHAJA_01934 8.1e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HILOHAJA_01935 0.0 yebA E COG1305 Transglutaminase-like enzymes
HILOHAJA_01936 7.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HILOHAJA_01937 3.6e-83 K Belongs to the sigma-70 factor family. ECF subfamily
HILOHAJA_01938 9.8e-248 S Domain of unknown function (DUF4179)
HILOHAJA_01939 5.1e-211 pbuG S permease
HILOHAJA_01940 3.5e-114 yebC M Membrane
HILOHAJA_01942 8.9e-93 yebE S UPF0316 protein
HILOHAJA_01943 8e-28 yebG S NETI protein
HILOHAJA_01944 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HILOHAJA_01945 5.9e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HILOHAJA_01946 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HILOHAJA_01947 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HILOHAJA_01948 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HILOHAJA_01949 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HILOHAJA_01950 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HILOHAJA_01951 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HILOHAJA_01952 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HILOHAJA_01953 7e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HILOHAJA_01954 1.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HILOHAJA_01955 1.3e-232 purD 6.3.4.13 F Belongs to the GARS family
HILOHAJA_01956 7.3e-71 K helix_turn_helix ASNC type
HILOHAJA_01957 8.9e-229 yjeH E Amino acid permease
HILOHAJA_01958 2.7e-27 S Protein of unknown function (DUF2892)
HILOHAJA_01959 0.0 yerA 3.5.4.2 F adenine deaminase
HILOHAJA_01960 3.4e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
HILOHAJA_01961 4.8e-51 yerC S protein conserved in bacteria
HILOHAJA_01962 5.7e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HILOHAJA_01963 8.4e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HILOHAJA_01964 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HILOHAJA_01965 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HILOHAJA_01966 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HILOHAJA_01967 9.2e-197 yerI S homoserine kinase type II (protein kinase fold)
HILOHAJA_01968 1.6e-123 sapB S MgtC SapB transporter
HILOHAJA_01969 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HILOHAJA_01970 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HILOHAJA_01971 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HILOHAJA_01972 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HILOHAJA_01973 1.3e-148 yerO K Transcriptional regulator
HILOHAJA_01974 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HILOHAJA_01975 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HILOHAJA_01976 4.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HILOHAJA_01977 4.3e-154 haeIIIM 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HILOHAJA_01978 6.8e-45 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HILOHAJA_01979 1.7e-113
HILOHAJA_01980 3.9e-93 V Restriction endonuclease
HILOHAJA_01982 1.4e-100 S response regulator aspartate phosphatase
HILOHAJA_01983 5.8e-29 S Colicin immunity protein / pyocin immunity protein
HILOHAJA_01985 2.6e-77 S Protein of unknown function, DUF600
HILOHAJA_01986 5e-60 S Protein of unknown function, DUF600
HILOHAJA_01987 2.2e-52 S Protein of unknown function, DUF600
HILOHAJA_01988 0.0 L nucleic acid phosphodiester bond hydrolysis
HILOHAJA_01990 3.6e-99 L endonuclease activity
HILOHAJA_01991 7.9e-51
HILOHAJA_01992 2.4e-209 S Tetratricopeptide repeat
HILOHAJA_01994 2.7e-126 yeeN K transcriptional regulatory protein
HILOHAJA_01996 6.1e-100 dhaR3 K Transcriptional regulator
HILOHAJA_01997 5.9e-79 yesE S SnoaL-like domain
HILOHAJA_01998 1.3e-151 yesF GM NAD(P)H-binding
HILOHAJA_01999 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HILOHAJA_02000 1.5e-45 cotJB S CotJB protein
HILOHAJA_02001 5.2e-104 cotJC P Spore Coat
HILOHAJA_02002 1.8e-101 yesJ K Acetyltransferase (GNAT) family
HILOHAJA_02004 1.2e-101 yesL S Protein of unknown function, DUF624
HILOHAJA_02005 0.0 yesM 2.7.13.3 T Histidine kinase
HILOHAJA_02006 1.6e-202 yesN K helix_turn_helix, arabinose operon control protein
HILOHAJA_02007 2.8e-246 yesO G Bacterial extracellular solute-binding protein
HILOHAJA_02008 1.4e-170 yesP G Binding-protein-dependent transport system inner membrane component
HILOHAJA_02009 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
HILOHAJA_02010 2.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HILOHAJA_02011 0.0 yesS K Transcriptional regulator
HILOHAJA_02012 2.2e-128 E GDSL-like Lipase/Acylhydrolase
HILOHAJA_02013 6e-128 yesU S Domain of unknown function (DUF1961)
HILOHAJA_02014 3e-113 yesV S Protein of unknown function, DUF624
HILOHAJA_02015 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HILOHAJA_02016 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HILOHAJA_02017 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
HILOHAJA_02018 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HILOHAJA_02019 0.0 yetA
HILOHAJA_02020 4.8e-290 lplA G Bacterial extracellular solute-binding protein
HILOHAJA_02021 1.9e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HILOHAJA_02022 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HILOHAJA_02023 5.4e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HILOHAJA_02024 5.2e-122 yetF S membrane
HILOHAJA_02025 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HILOHAJA_02026 4.4e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HILOHAJA_02027 2.2e-34
HILOHAJA_02028 1.6e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HILOHAJA_02029 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HILOHAJA_02030 5.3e-105 yetJ S Belongs to the BI1 family
HILOHAJA_02031 8.3e-31 yetM CH FAD binding domain
HILOHAJA_02032 3.5e-104 mrr L restriction endonuclease
HILOHAJA_02033 1.6e-194 yetN S Protein of unknown function (DUF3900)
HILOHAJA_02034 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HILOHAJA_02035 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HILOHAJA_02036 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
HILOHAJA_02037 1.9e-172 yfnG 4.2.1.45 M dehydratase
HILOHAJA_02038 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
HILOHAJA_02039 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HILOHAJA_02040 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
HILOHAJA_02041 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
HILOHAJA_02042 8.1e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HILOHAJA_02043 8.4e-241 yfnA E amino acid
HILOHAJA_02044 3.7e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HILOHAJA_02045 1.1e-113 yfmS NT chemotaxis protein
HILOHAJA_02046 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HILOHAJA_02047 1.7e-73 yfmQ S Uncharacterised protein from bacillus cereus group
HILOHAJA_02048 1.4e-69 yfmP K transcriptional
HILOHAJA_02049 1.5e-209 yfmO EGP Major facilitator Superfamily
HILOHAJA_02050 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HILOHAJA_02051 1.2e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HILOHAJA_02052 3.2e-77 yfmK 2.3.1.128 K acetyltransferase
HILOHAJA_02053 7.2e-189 yfmJ S N-terminal domain of oxidoreductase
HILOHAJA_02054 2.9e-213 G Major Facilitator Superfamily
HILOHAJA_02055 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
HILOHAJA_02056 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HILOHAJA_02057 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILOHAJA_02058 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILOHAJA_02059 1.4e-167 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HILOHAJA_02060 2.9e-24 S Protein of unknown function (DUF3212)
HILOHAJA_02061 7.6e-58 yflT S Heat induced stress protein YflT
HILOHAJA_02062 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HILOHAJA_02063 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
HILOHAJA_02064 2.2e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HILOHAJA_02065 2.2e-117 citT T response regulator
HILOHAJA_02066 7.5e-180 yflP S Tripartite tricarboxylate transporter family receptor
HILOHAJA_02067 1.9e-226 citM C Citrate transporter
HILOHAJA_02068 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HILOHAJA_02069 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HILOHAJA_02070 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HILOHAJA_02071 1.2e-120 yflK S protein conserved in bacteria
HILOHAJA_02072 4e-18 yflJ S Protein of unknown function (DUF2639)
HILOHAJA_02073 5.4e-19 yflI
HILOHAJA_02074 5.3e-50 yflH S Protein of unknown function (DUF3243)
HILOHAJA_02075 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HILOHAJA_02076 8.2e-249 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HILOHAJA_02077 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HILOHAJA_02078 6e-67 yhdN S Domain of unknown function (DUF1992)
HILOHAJA_02079 2.2e-252 agcS_1 E Sodium alanine symporter
HILOHAJA_02080 4e-27 yfkQ EG Spore germination protein
HILOHAJA_02081 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILOHAJA_02082 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HILOHAJA_02083 1.8e-133 treR K transcriptional
HILOHAJA_02084 1.2e-123 yfkO C nitroreductase
HILOHAJA_02085 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HILOHAJA_02086 8.7e-90 yfkM 1.11.1.6, 3.5.1.124 S protease
HILOHAJA_02087 8.9e-207 ydiM EGP Major facilitator Superfamily
HILOHAJA_02088 2.1e-29 yfkK S Belongs to the UPF0435 family
HILOHAJA_02089 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HILOHAJA_02090 2.4e-50 yfkI S gas vesicle protein
HILOHAJA_02091 1.3e-143 yihY S Belongs to the UPF0761 family
HILOHAJA_02092 5e-08
HILOHAJA_02093 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HILOHAJA_02094 1.8e-182 cax P COG0387 Ca2 H antiporter
HILOHAJA_02095 1.2e-146 yfkD S YfkD-like protein
HILOHAJA_02096 6e-149 yfkC M Mechanosensitive ion channel
HILOHAJA_02097 5.4e-222 yfkA S YfkB-like domain
HILOHAJA_02098 1.1e-26 yfjT
HILOHAJA_02099 2.6e-154 pdaA G deacetylase
HILOHAJA_02100 3.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HILOHAJA_02101 1.7e-184 corA P Mediates influx of magnesium ions
HILOHAJA_02102 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HILOHAJA_02103 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HILOHAJA_02104 1.6e-39 S YfzA-like protein
HILOHAJA_02105 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HILOHAJA_02106 1.1e-83 yfjM S Psort location Cytoplasmic, score
HILOHAJA_02107 3e-29 yfjL
HILOHAJA_02108 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HILOHAJA_02109 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HILOHAJA_02110 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HILOHAJA_02111 2.4e-256 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HILOHAJA_02112 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HILOHAJA_02113 1.2e-25 sspH S Belongs to the SspH family
HILOHAJA_02114 4e-56 yfjF S UPF0060 membrane protein
HILOHAJA_02115 5e-80 S Family of unknown function (DUF5381)
HILOHAJA_02116 1.8e-101 yfjD S Family of unknown function (DUF5381)
HILOHAJA_02117 4.1e-144 yfjC
HILOHAJA_02118 9.2e-191 yfjB
HILOHAJA_02119 1.1e-44 yfjA S Belongs to the WXG100 family
HILOHAJA_02120 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HILOHAJA_02121 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
HILOHAJA_02122 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILOHAJA_02123 2.1e-310 yfiB3 V ABC transporter
HILOHAJA_02124 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HILOHAJA_02125 9.8e-65 mhqP S DoxX
HILOHAJA_02126 5.7e-163 yfiE 1.13.11.2 S glyoxalase
HILOHAJA_02127 1.5e-177 K AraC-like ligand binding domain
HILOHAJA_02128 1.8e-262 iolT EGP Major facilitator Superfamily
HILOHAJA_02129 8.4e-184 G Xylose isomerase
HILOHAJA_02130 1.1e-233 S Oxidoreductase
HILOHAJA_02132 1.1e-214 yxjM T Histidine kinase
HILOHAJA_02133 3.2e-113 KT LuxR family transcriptional regulator
HILOHAJA_02134 6.2e-171 V ABC transporter, ATP-binding protein
HILOHAJA_02135 2.3e-207 V ABC-2 family transporter protein
HILOHAJA_02136 2.2e-202 V COG0842 ABC-type multidrug transport system, permease component
HILOHAJA_02137 2e-58 padR K transcriptional
HILOHAJA_02138 5.4e-63 ytkC S Bacteriophage holin family
HILOHAJA_02139 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HILOHAJA_02140 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HILOHAJA_02141 1.4e-144 ytlC P ABC transporter
HILOHAJA_02142 3.2e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HILOHAJA_02143 2.1e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HILOHAJA_02144 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HILOHAJA_02145 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HILOHAJA_02146 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HILOHAJA_02147 0.0 asnB 6.3.5.4 E Asparagine synthase
HILOHAJA_02148 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HILOHAJA_02149 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HILOHAJA_02150 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HILOHAJA_02151 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HILOHAJA_02152 2.8e-105 ytqB J Putative rRNA methylase
HILOHAJA_02153 1.8e-189 yhcC S Fe-S oxidoreductase
HILOHAJA_02154 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HILOHAJA_02156 5.1e-66 ytrA K GntR family transcriptional regulator
HILOHAJA_02157 4.2e-161 ytrB P abc transporter atp-binding protein
HILOHAJA_02158 5.7e-159 P ABC-2 family transporter protein
HILOHAJA_02159 1.3e-147
HILOHAJA_02160 3.1e-127 ytrE V ABC transporter, ATP-binding protein
HILOHAJA_02161 5.5e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HILOHAJA_02162 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILOHAJA_02163 1.2e-185 T PhoQ Sensor
HILOHAJA_02164 1.1e-138 bceA V ABC transporter, ATP-binding protein
HILOHAJA_02165 0.0 bceB V ABC transporter (permease)
HILOHAJA_02166 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HILOHAJA_02167 2.3e-210 yttB EGP Major facilitator Superfamily
HILOHAJA_02170 1.6e-84 ydcK S Belongs to the SprT family
HILOHAJA_02171 0.0 yhgF K COG2183 Transcriptional accessory protein
HILOHAJA_02172 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
HILOHAJA_02173 1.5e-82 ydcG S EVE domain
HILOHAJA_02177 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HILOHAJA_02178 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HILOHAJA_02179 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HILOHAJA_02180 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HILOHAJA_02181 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HILOHAJA_02182 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HILOHAJA_02183 5.2e-57 rsbS T antagonist
HILOHAJA_02184 1.3e-143 rsbR T Positive regulator of sigma-B
HILOHAJA_02185 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HILOHAJA_02186 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HILOHAJA_02187 2.1e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HILOHAJA_02188 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HILOHAJA_02189 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HILOHAJA_02190 2.2e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HILOHAJA_02191 1.1e-259 ydbT S Membrane
HILOHAJA_02192 2.1e-82 ydbS S Bacterial PH domain
HILOHAJA_02193 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HILOHAJA_02194 6e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HILOHAJA_02195 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HILOHAJA_02196 4.3e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HILOHAJA_02197 2.1e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HILOHAJA_02198 2.2e-07 S Fur-regulated basic protein A
HILOHAJA_02199 1.1e-18 S Fur-regulated basic protein B
HILOHAJA_02200 1.4e-217 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HILOHAJA_02201 2.7e-52 ydbL
HILOHAJA_02202 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HILOHAJA_02203 1e-170 ydbJ V ABC transporter, ATP-binding protein
HILOHAJA_02204 9.7e-181 ydbI S AI-2E family transporter
HILOHAJA_02205 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HILOHAJA_02206 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
HILOHAJA_02207 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HILOHAJA_02208 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HILOHAJA_02209 3.5e-154 ydbD P Catalase
HILOHAJA_02210 3.1e-62 ydbC S Domain of unknown function (DUF4937
HILOHAJA_02211 8.9e-59 ydbB G Cupin domain
HILOHAJA_02213 2.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HILOHAJA_02214 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HILOHAJA_02216 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HILOHAJA_02217 2.1e-39
HILOHAJA_02218 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HILOHAJA_02219 8.5e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HILOHAJA_02220 0.0 ydaO E amino acid
HILOHAJA_02221 0.0 ydaN S Bacterial cellulose synthase subunit
HILOHAJA_02222 4.5e-233 ydaM M Glycosyl transferase family group 2
HILOHAJA_02223 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HILOHAJA_02224 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
HILOHAJA_02225 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HILOHAJA_02226 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HILOHAJA_02227 2.5e-74 lrpC K Transcriptional regulator
HILOHAJA_02228 3.3e-46 ydzA EGP Major facilitator Superfamily
HILOHAJA_02229 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HILOHAJA_02230 6.8e-77 ydaG 1.4.3.5 S general stress protein
HILOHAJA_02231 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HILOHAJA_02232 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HILOHAJA_02233 9.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILOHAJA_02234 9e-99 ydaC Q Methyltransferase domain
HILOHAJA_02235 2.1e-293 ydaB IQ acyl-CoA ligase
HILOHAJA_02236 0.0 mtlR K transcriptional regulator, MtlR
HILOHAJA_02237 2.8e-176 ydhF S Oxidoreductase
HILOHAJA_02238 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HILOHAJA_02239 1.4e-49 yczJ S biosynthesis
HILOHAJA_02241 2.2e-119 ycsK E anatomical structure formation involved in morphogenesis
HILOHAJA_02242 1.2e-132 kipR K Transcriptional regulator
HILOHAJA_02243 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HILOHAJA_02244 8e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HILOHAJA_02245 4e-147 ycsI S Belongs to the D-glutamate cyclase family
HILOHAJA_02246 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HILOHAJA_02247 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
HILOHAJA_02248 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HILOHAJA_02250 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HILOHAJA_02251 1.9e-112 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HILOHAJA_02252 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HILOHAJA_02253 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HILOHAJA_02254 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HILOHAJA_02255 1.3e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HILOHAJA_02256 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HILOHAJA_02257 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HILOHAJA_02258 7.3e-56
HILOHAJA_02259 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HILOHAJA_02260 4.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
HILOHAJA_02261 2.9e-100 ycnI S protein conserved in bacteria
HILOHAJA_02262 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HILOHAJA_02263 1.8e-148 glcU U Glucose uptake
HILOHAJA_02264 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HILOHAJA_02265 2e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HILOHAJA_02266 5.6e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILOHAJA_02267 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HILOHAJA_02268 1.6e-45 ycnE S Monooxygenase
HILOHAJA_02269 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HILOHAJA_02270 7.1e-153 ycnC K Transcriptional regulator
HILOHAJA_02271 1.4e-251 ycnB EGP Major facilitator Superfamily
HILOHAJA_02272 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HILOHAJA_02273 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HILOHAJA_02274 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILOHAJA_02275 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILOHAJA_02276 9.8e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
HILOHAJA_02279 5.2e-71 S aspartate phosphatase
HILOHAJA_02280 1.7e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HILOHAJA_02281 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILOHAJA_02282 3.6e-202 yclI V ABC transporter (permease) YclI
HILOHAJA_02283 1.9e-121 yclH P ABC transporter
HILOHAJA_02284 1.7e-199 gerKB F Spore germination protein
HILOHAJA_02285 1.3e-232 gerKC S spore germination
HILOHAJA_02286 1.8e-279 gerKA EG Spore germination protein
HILOHAJA_02288 2.9e-310 yclG M Pectate lyase superfamily protein
HILOHAJA_02289 1.5e-267 dtpT E amino acid peptide transporter
HILOHAJA_02290 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
HILOHAJA_02291 1.1e-83 yclD
HILOHAJA_02292 4e-39 bsdD 4.1.1.61 S response to toxic substance
HILOHAJA_02293 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HILOHAJA_02294 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HILOHAJA_02295 4.9e-162 bsdA K LysR substrate binding domain
HILOHAJA_02296 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HILOHAJA_02297 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HILOHAJA_02298 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HILOHAJA_02299 9.7e-115 yczE S membrane
HILOHAJA_02300 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HILOHAJA_02301 4.4e-255 ycxD K GntR family transcriptional regulator
HILOHAJA_02302 1.4e-162 ycxC EG EamA-like transporter family
HILOHAJA_02303 5.5e-90 S YcxB-like protein
HILOHAJA_02304 3e-226 EGP Major Facilitator Superfamily
HILOHAJA_02305 2.9e-139 srfAD Q thioesterase
HILOHAJA_02306 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HILOHAJA_02307 1.4e-245 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILOHAJA_02308 3.3e-248 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HILOHAJA_02310 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
HILOHAJA_02311 2.7e-140 ybbA S Putative esterase
HILOHAJA_02312 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILOHAJA_02313 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HILOHAJA_02314 1.4e-165 feuA P Iron-uptake system-binding protein
HILOHAJA_02315 1e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HILOHAJA_02316 1.6e-238 ybbC 3.2.1.52 S protein conserved in bacteria
HILOHAJA_02317 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HILOHAJA_02318 2.9e-251 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HILOHAJA_02319 2.2e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HILOHAJA_02320 1.2e-149 ybbH K transcriptional
HILOHAJA_02321 8.8e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HILOHAJA_02322 1.9e-86 ybbJ J acetyltransferase
HILOHAJA_02323 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HILOHAJA_02324 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILOHAJA_02325 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILOHAJA_02326 1.1e-229 mdr EGP Major facilitator Superfamily
HILOHAJA_02327 1e-290 lctP C L-lactate permease
HILOHAJA_02328 1.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HILOHAJA_02329 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HILOHAJA_02330 4.1e-81 ycgB
HILOHAJA_02331 3.6e-255 ycgA S Membrane
HILOHAJA_02332 1.4e-217 amhX S amidohydrolase
HILOHAJA_02333 5.3e-164 opuAC E glycine betaine
HILOHAJA_02334 2.5e-126 opuAB P glycine betaine
HILOHAJA_02335 5.1e-229 proV 3.6.3.32 E glycine betaine
HILOHAJA_02336 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HILOHAJA_02337 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
HILOHAJA_02338 3e-218 naiP P Uncharacterised MFS-type transporter YbfB
HILOHAJA_02339 2e-192 yceH P Belongs to the TelA family
HILOHAJA_02340 0.0 yceG S Putative component of 'biosynthetic module'
HILOHAJA_02341 1.4e-136 terC P Protein of unknown function (DUF475)
HILOHAJA_02342 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HILOHAJA_02343 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HILOHAJA_02344 2.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HILOHAJA_02345 2.7e-188 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HILOHAJA_02346 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HILOHAJA_02347 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HILOHAJA_02348 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
HILOHAJA_02349 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HILOHAJA_02350 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HILOHAJA_02351 1.2e-173 S response regulator aspartate phosphatase
HILOHAJA_02352 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
HILOHAJA_02353 8.7e-260 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HILOHAJA_02354 1.5e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HILOHAJA_02355 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HILOHAJA_02356 3.5e-174 yccK C Aldo keto reductase
HILOHAJA_02357 6.4e-202 natB CP ABC-2 family transporter protein
HILOHAJA_02358 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HILOHAJA_02359 1.2e-126 lytR_2 T LytTr DNA-binding domain
HILOHAJA_02360 2.9e-160 2.7.13.3 T GHKL domain
HILOHAJA_02361 8.1e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
HILOHAJA_02362 3.4e-59 S RDD family
HILOHAJA_02363 7.3e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HILOHAJA_02364 1.8e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HILOHAJA_02365 4.1e-101 yxaF K Transcriptional regulator
HILOHAJA_02366 3e-225 lmrB EGP the major facilitator superfamily
HILOHAJA_02367 1.2e-200 ycbU E Selenocysteine lyase
HILOHAJA_02368 6.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HILOHAJA_02369 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HILOHAJA_02370 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HILOHAJA_02371 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HILOHAJA_02372 1.9e-135 ycbR T vWA found in TerF C terminus
HILOHAJA_02373 1.3e-78 sleB 3.5.1.28 M Cell wall
HILOHAJA_02374 4.1e-52 ycbP S Protein of unknown function (DUF2512)
HILOHAJA_02375 6e-115 S ABC-2 family transporter protein
HILOHAJA_02376 3.1e-167 ycbN V ABC transporter, ATP-binding protein
HILOHAJA_02377 1.7e-168 T PhoQ Sensor
HILOHAJA_02378 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HILOHAJA_02379 1.5e-169 eamA1 EG spore germination
HILOHAJA_02380 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HILOHAJA_02381 3.7e-176 ycbJ S Macrolide 2'-phosphotransferase
HILOHAJA_02382 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
HILOHAJA_02383 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HILOHAJA_02384 1.8e-35 bofA S Sigma-K factor-processing regulatory protein BofA
HILOHAJA_02385 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HILOHAJA_02386 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HILOHAJA_02387 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HILOHAJA_02388 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HILOHAJA_02389 3.3e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HILOHAJA_02390 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
HILOHAJA_02391 1.2e-212 yaaH M Glycoside Hydrolase Family
HILOHAJA_02392 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HILOHAJA_02393 6.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HILOHAJA_02394 1.3e-09
HILOHAJA_02395 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HILOHAJA_02396 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HILOHAJA_02397 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HILOHAJA_02398 8.9e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HILOHAJA_02399 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HILOHAJA_02400 1e-181 yaaC S YaaC-like Protein
HILOHAJA_02401 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HILOHAJA_02402 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HILOHAJA_02403 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HILOHAJA_02404 8.4e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HILOHAJA_02405 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HILOHAJA_02406 9.9e-77 tspO T membrane
HILOHAJA_02407 4.8e-204 cotI S Spore coat protein
HILOHAJA_02408 1.8e-217 cotSA M Glycosyl transferases group 1
HILOHAJA_02409 1.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
HILOHAJA_02411 3e-234 ytcC M Glycosyltransferase Family 4
HILOHAJA_02412 6.3e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HILOHAJA_02413 9.8e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HILOHAJA_02414 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
HILOHAJA_02415 4.4e-132 dksA T COG1734 DnaK suppressor protein
HILOHAJA_02416 9.4e-272 menF 5.4.4.2 HQ Isochorismate synthase
HILOHAJA_02417 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HILOHAJA_02418 3.8e-151 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HILOHAJA_02419 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HILOHAJA_02420 3.7e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HILOHAJA_02421 7.8e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HILOHAJA_02422 1.7e-168 troA P Belongs to the bacterial solute-binding protein 9 family
HILOHAJA_02423 3.8e-139 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HILOHAJA_02424 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HILOHAJA_02425 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HILOHAJA_02426 1.1e-24 S Domain of Unknown Function (DUF1540)
HILOHAJA_02427 1.1e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HILOHAJA_02428 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
HILOHAJA_02429 3.6e-41 rpmE2 J Ribosomal protein L31
HILOHAJA_02430 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HILOHAJA_02431 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HILOHAJA_02432 1.1e-72 ytkA S YtkA-like
HILOHAJA_02434 2.1e-76 dps P Belongs to the Dps family
HILOHAJA_02435 1.3e-91 ykoE S ABC-type cobalt transport system, permease component
HILOHAJA_02436 2e-305 P ABC transporter, ATP-binding protein
HILOHAJA_02437 2.9e-134 ykoC P Cobalt transport protein
HILOHAJA_02438 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HILOHAJA_02439 1.1e-175 isp O Belongs to the peptidase S8 family
HILOHAJA_02440 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HILOHAJA_02442 4.2e-71 ohrB O Organic hydroperoxide resistance protein
HILOHAJA_02443 2.2e-73 ohrR K COG1846 Transcriptional regulators
HILOHAJA_02444 2.8e-70 ohrA O Organic hydroperoxide resistance protein
HILOHAJA_02445 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HILOHAJA_02446 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HILOHAJA_02447 1.2e-168 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HILOHAJA_02448 2.7e-49 ykkD P Multidrug resistance protein
HILOHAJA_02449 3.5e-55 ykkC P Multidrug resistance protein
HILOHAJA_02450 5.6e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HILOHAJA_02451 7.4e-97 ykkA S Protein of unknown function (DUF664)
HILOHAJA_02452 1.7e-128 ykjA S Protein of unknown function (DUF421)
HILOHAJA_02453 9.5e-225 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HILOHAJA_02454 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HILOHAJA_02455 5.9e-160 ykgA E Amidinotransferase
HILOHAJA_02456 6.9e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
HILOHAJA_02457 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
HILOHAJA_02458 2.2e-165 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HILOHAJA_02459 7.5e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HILOHAJA_02460 1.2e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HILOHAJA_02462 0.0 dppE E ABC transporter substrate-binding protein
HILOHAJA_02463 1.9e-186 dppD P Belongs to the ABC transporter superfamily
HILOHAJA_02464 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILOHAJA_02465 7.8e-155 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILOHAJA_02466 1.5e-152 dppA E D-aminopeptidase
HILOHAJA_02467 8.2e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HILOHAJA_02468 1.9e-208 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HILOHAJA_02470 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HILOHAJA_02471 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HILOHAJA_02473 4.6e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HILOHAJA_02474 1.2e-241 steT E amino acid
HILOHAJA_02475 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HILOHAJA_02476 7.6e-175 pit P phosphate transporter
HILOHAJA_02477 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HILOHAJA_02478 6.7e-23 spoIISB S Stage II sporulation protein SB
HILOHAJA_02479 2.9e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HILOHAJA_02480 9.3e-40 xhlB S SPP1 phage holin
HILOHAJA_02481 2.8e-39 xhlA S Haemolysin XhlA
HILOHAJA_02482 1.2e-154 xepA
HILOHAJA_02483 1.7e-23 xkdX
HILOHAJA_02484 2.6e-55 xkdW S XkdW protein
HILOHAJA_02485 0.0
HILOHAJA_02486 6.7e-41
HILOHAJA_02487 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HILOHAJA_02488 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HILOHAJA_02489 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HILOHAJA_02490 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HILOHAJA_02491 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HILOHAJA_02492 3.7e-122 xkdP S Lysin motif
HILOHAJA_02493 0.0 xkdO L Transglycosylase SLT domain
HILOHAJA_02494 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HILOHAJA_02495 6.1e-76 xkdM S Phage tail tube protein
HILOHAJA_02496 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HILOHAJA_02497 1.9e-77 xkdJ
HILOHAJA_02498 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HILOHAJA_02499 8.7e-65 yqbH S Domain of unknown function (DUF3599)
HILOHAJA_02500 5.5e-65 yqbG S Protein of unknown function (DUF3199)
HILOHAJA_02501 1.3e-168 xkdG S Phage capsid family
HILOHAJA_02502 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HILOHAJA_02503 6e-285 yqbA S portal protein
HILOHAJA_02504 1.4e-253 xtmB S phage terminase, large subunit
HILOHAJA_02505 5.3e-139 xtmA L phage terminase small subunit
HILOHAJA_02506 6.5e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HILOHAJA_02507 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HILOHAJA_02510 9.2e-118 xkdC L Bacterial dnaA protein
HILOHAJA_02511 5e-156 xkdB K sequence-specific DNA binding
HILOHAJA_02513 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HILOHAJA_02514 4.3e-109 xkdA E IrrE N-terminal-like domain
HILOHAJA_02515 4.4e-160 ydbD P Catalase
HILOHAJA_02516 2.1e-111 yjqB S Pfam:DUF867
HILOHAJA_02517 1.8e-60 yjqA S Bacterial PH domain
HILOHAJA_02518 2.9e-168 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HILOHAJA_02519 6.3e-41 S YCII-related domain
HILOHAJA_02521 1e-212 S response regulator aspartate phosphatase
HILOHAJA_02522 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HILOHAJA_02523 2.3e-78 yjoA S DinB family
HILOHAJA_02524 4.3e-130 MA20_18170 S membrane transporter protein
HILOHAJA_02525 1.7e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HILOHAJA_02526 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HILOHAJA_02527 5.2e-184 exuR K transcriptional
HILOHAJA_02528 9.1e-226 exuT G Sugar (and other) transporter
HILOHAJA_02529 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HILOHAJA_02530 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HILOHAJA_02531 6.3e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HILOHAJA_02532 2.8e-193 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HILOHAJA_02533 5.8e-250 yjmB G symporter YjmB
HILOHAJA_02534 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
HILOHAJA_02535 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HILOHAJA_02536 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HILOHAJA_02537 2.8e-93 yjlB S Cupin domain
HILOHAJA_02538 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
HILOHAJA_02539 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HILOHAJA_02540 1.9e-122 ybbM S transport system, permease component
HILOHAJA_02541 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HILOHAJA_02542 8.2e-30
HILOHAJA_02543 5.9e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HILOHAJA_02544 5.4e-220 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HILOHAJA_02546 8.4e-116 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HILOHAJA_02547 1.5e-06 S Domain of unknown function (DUF4352)
HILOHAJA_02548 1.6e-94 yjgD S Protein of unknown function (DUF1641)
HILOHAJA_02549 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HILOHAJA_02550 1.4e-101 yjgB S Domain of unknown function (DUF4309)
HILOHAJA_02551 1.2e-45 T PhoQ Sensor
HILOHAJA_02552 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
HILOHAJA_02553 2.3e-20 yjfB S Putative motility protein
HILOHAJA_02554 5.5e-83 S Protein of unknown function (DUF2690)
HILOHAJA_02555 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HILOHAJA_02557 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HILOHAJA_02558 1.7e-51 yjdJ S Domain of unknown function (DUF4306)
HILOHAJA_02559 4.2e-29 S Domain of unknown function (DUF4177)
HILOHAJA_02560 1.3e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HILOHAJA_02562 1e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HILOHAJA_02563 4.5e-49 yjdF S Protein of unknown function (DUF2992)
HILOHAJA_02564 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HILOHAJA_02565 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HILOHAJA_02566 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HILOHAJA_02568 1.7e-139 IQ Enoyl-(Acyl carrier protein) reductase
HILOHAJA_02569 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
HILOHAJA_02570 1.1e-92 yqaS L DNA packaging
HILOHAJA_02571 4.1e-49 S YjcQ protein
HILOHAJA_02572 1.6e-72 yjcP
HILOHAJA_02573 8.5e-81 L Transposase
HILOHAJA_02576 2.6e-44 yjcN
HILOHAJA_02577 2.1e-190 S Putative amidase domain
HILOHAJA_02580 5.4e-212 yjcL S Protein of unknown function (DUF819)
HILOHAJA_02581 7.7e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
HILOHAJA_02582 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HILOHAJA_02583 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HILOHAJA_02584 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
HILOHAJA_02585 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HILOHAJA_02586 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HILOHAJA_02587 1.7e-38
HILOHAJA_02588 0.0 yjcD 3.6.4.12 L DNA helicase
HILOHAJA_02589 2.9e-38 spoVIF S Stage VI sporulation protein F
HILOHAJA_02592 4.3e-56 yjcA S Protein of unknown function (DUF1360)
HILOHAJA_02593 1.1e-54 cotV S Spore Coat Protein X and V domain
HILOHAJA_02594 8.8e-24 cotW
HILOHAJA_02595 1.6e-72 cotX S Spore Coat Protein X and V domain
HILOHAJA_02596 7.6e-96 cotY S Spore coat protein Z
HILOHAJA_02597 4.4e-82 cotZ S Spore coat protein
HILOHAJA_02598 5.9e-54 yjbX S Spore coat protein
HILOHAJA_02599 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HILOHAJA_02600 2.2e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HILOHAJA_02601 5.1e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HILOHAJA_02602 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HILOHAJA_02603 2.6e-29 thiS H thiamine diphosphate biosynthetic process
HILOHAJA_02604 5.7e-216 thiO 1.4.3.19 E Glycine oxidase
HILOHAJA_02605 3.5e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HILOHAJA_02606 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HILOHAJA_02607 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HILOHAJA_02608 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HILOHAJA_02609 1.2e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HILOHAJA_02610 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HILOHAJA_02611 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HILOHAJA_02612 7.1e-62 yjbL S Belongs to the UPF0738 family
HILOHAJA_02613 2.4e-101 yjbK S protein conserved in bacteria
HILOHAJA_02614 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HILOHAJA_02615 3.7e-72 yjbI S Bacterial-like globin
HILOHAJA_02616 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HILOHAJA_02618 1.8e-20
HILOHAJA_02619 0.0 pepF E oligoendopeptidase F
HILOHAJA_02620 2.3e-223 yjbF S Competence protein
HILOHAJA_02621 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HILOHAJA_02622 6e-112 yjbE P Integral membrane protein TerC family
HILOHAJA_02623 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HILOHAJA_02624 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HILOHAJA_02625 2.2e-205 yjbB EGP Major Facilitator Superfamily
HILOHAJA_02626 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HILOHAJA_02627 6.8e-198 oppD P Belongs to the ABC transporter superfamily
HILOHAJA_02628 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILOHAJA_02629 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILOHAJA_02630 0.0 oppA E ABC transporter substrate-binding protein
HILOHAJA_02631 4e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HILOHAJA_02632 5e-147 yjbA S Belongs to the UPF0736 family
HILOHAJA_02633 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILOHAJA_02634 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HILOHAJA_02635 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HILOHAJA_02636 5.9e-82 appF E Belongs to the ABC transporter superfamily
HILOHAJA_02637 1.8e-184 appD P Belongs to the ABC transporter superfamily
HILOHAJA_02638 7.8e-151 yjaZ O Zn-dependent protease
HILOHAJA_02639 4e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HILOHAJA_02640 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HILOHAJA_02641 2.7e-22 yjzB
HILOHAJA_02642 7.3e-26 comZ S ComZ
HILOHAJA_02643 2.5e-183 med S Transcriptional activator protein med
HILOHAJA_02644 1.3e-99 yjaV
HILOHAJA_02645 1.1e-141 yjaU I carboxylic ester hydrolase activity
HILOHAJA_02646 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HILOHAJA_02647 9.5e-28 yjzC S YjzC-like protein
HILOHAJA_02648 8.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HILOHAJA_02649 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HILOHAJA_02650 1.1e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HILOHAJA_02651 5.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HILOHAJA_02652 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HILOHAJA_02653 6.5e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HILOHAJA_02654 1.8e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HILOHAJA_02655 1.7e-88 norB G Major Facilitator Superfamily
HILOHAJA_02656 8.3e-268 yitY C D-arabinono-1,4-lactone oxidase
HILOHAJA_02657 1.5e-22 pilT S Proteolipid membrane potential modulator
HILOHAJA_02658 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HILOHAJA_02659 3.8e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HILOHAJA_02660 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HILOHAJA_02662 1.2e-17 S Protein of unknown function (DUF3813)
HILOHAJA_02663 5e-73 ipi S Intracellular proteinase inhibitor
HILOHAJA_02664 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HILOHAJA_02665 9.3e-158 yitS S protein conserved in bacteria
HILOHAJA_02666 2.2e-311 nprB 3.4.24.28 E Peptidase M4
HILOHAJA_02667 1.4e-44 yitR S Domain of unknown function (DUF3784)
HILOHAJA_02668 2e-95
HILOHAJA_02669 1.5e-58 K Transcriptional regulator PadR-like family
HILOHAJA_02670 1.5e-97 S Sporulation delaying protein SdpA
HILOHAJA_02671 1.4e-170
HILOHAJA_02672 1.9e-93
HILOHAJA_02673 6.9e-161 cvfB S protein conserved in bacteria
HILOHAJA_02674 5.6e-54 yajQ S Belongs to the UPF0234 family
HILOHAJA_02675 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HILOHAJA_02676 1.2e-71 yjcF S Acetyltransferase (GNAT) domain
HILOHAJA_02677 2.3e-148 yitH K Acetyltransferase (GNAT) domain
HILOHAJA_02678 7.5e-228 yitG EGP Major facilitator Superfamily
HILOHAJA_02679 4.7e-218 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HILOHAJA_02680 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HILOHAJA_02681 1.6e-140 yitD 4.4.1.19 S synthase
HILOHAJA_02682 9.9e-118 comB 3.1.3.71 H Belongs to the ComB family
HILOHAJA_02683 2.1e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HILOHAJA_02684 1.3e-229 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HILOHAJA_02685 1.4e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HILOHAJA_02686 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HILOHAJA_02687 6.8e-36 mcbG S Pentapeptide repeats (9 copies)
HILOHAJA_02688 5.8e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HILOHAJA_02689 1.4e-99 argO S Lysine exporter protein LysE YggA
HILOHAJA_02690 7e-92 yisT S DinB family
HILOHAJA_02691 1.4e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HILOHAJA_02692 3.2e-190 yueF S transporter activity
HILOHAJA_02693 2.1e-32 yueG S Spore germination protein gerPA/gerPF
HILOHAJA_02694 7.4e-39 yueH S YueH-like protein
HILOHAJA_02695 2.3e-66 yueI S Protein of unknown function (DUF1694)
HILOHAJA_02696 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
HILOHAJA_02697 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HILOHAJA_02698 8.6e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HILOHAJA_02699 1.1e-22 yuzC
HILOHAJA_02701 7.5e-140 comQ H Belongs to the FPP GGPP synthase family
HILOHAJA_02703 7.1e-269 comP 2.7.13.3 T Histidine kinase
HILOHAJA_02704 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HILOHAJA_02705 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HILOHAJA_02706 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HILOHAJA_02707 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HILOHAJA_02708 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HILOHAJA_02709 1.9e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HILOHAJA_02710 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HILOHAJA_02711 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HILOHAJA_02712 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HILOHAJA_02713 3.2e-14
HILOHAJA_02714 1.3e-233 maeN C COG3493 Na citrate symporter
HILOHAJA_02715 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HILOHAJA_02716 1.9e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HILOHAJA_02717 3.2e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HILOHAJA_02718 2.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HILOHAJA_02719 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HILOHAJA_02720 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HILOHAJA_02721 3.1e-77 yufK S Family of unknown function (DUF5366)
HILOHAJA_02722 1.8e-74 yuxK S protein conserved in bacteria
HILOHAJA_02723 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HILOHAJA_02724 1.9e-184 yuxJ EGP Major facilitator Superfamily
HILOHAJA_02726 1.9e-115 kapD L the KinA pathway to sporulation
HILOHAJA_02727 6.3e-69 kapB G Kinase associated protein B
HILOHAJA_02728 4.6e-233 T PhoQ Sensor
HILOHAJA_02729 1.6e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HILOHAJA_02730 1.6e-39 yugE S Domain of unknown function (DUF1871)
HILOHAJA_02731 2.5e-155 yugF I Hydrolase
HILOHAJA_02732 1.6e-85 alaR K Transcriptional regulator
HILOHAJA_02733 2.1e-199 yugH 2.6.1.1 E Aminotransferase
HILOHAJA_02734 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HILOHAJA_02735 1.1e-34 yuzA S Domain of unknown function (DUF378)
HILOHAJA_02736 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HILOHAJA_02737 2.4e-228 yugK C Dehydrogenase
HILOHAJA_02738 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HILOHAJA_02740 1.3e-72 yugN S YugN-like family
HILOHAJA_02741 3.1e-181 yugO P COG1226 Kef-type K transport systems
HILOHAJA_02742 3.2e-53 mstX S Membrane-integrating protein Mistic
HILOHAJA_02743 2.3e-38
HILOHAJA_02744 1.4e-116 yugP S Zn-dependent protease
HILOHAJA_02745 2.4e-234 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HILOHAJA_02746 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HILOHAJA_02747 8.2e-72 yugU S Uncharacterised protein family UPF0047
HILOHAJA_02748 6.7e-35
HILOHAJA_02749 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HILOHAJA_02750 3.2e-225 mcpA NT chemotaxis protein
HILOHAJA_02751 6.9e-220 mcpA NT chemotaxis protein
HILOHAJA_02752 3.6e-293 mcpA NT chemotaxis protein
HILOHAJA_02753 9.6e-238 mcpA NT chemotaxis protein
HILOHAJA_02754 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HILOHAJA_02755 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HILOHAJA_02756 7.2e-275 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HILOHAJA_02757 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HILOHAJA_02758 1.2e-249 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HILOHAJA_02759 3.3e-183 ygjR S Oxidoreductase
HILOHAJA_02760 1.3e-194 yubA S transporter activity
HILOHAJA_02761 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HILOHAJA_02763 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HILOHAJA_02764 2.2e-274 yubD P Major Facilitator Superfamily
HILOHAJA_02765 9.3e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HILOHAJA_02766 4.6e-39 yiaA S yiaA/B two helix domain
HILOHAJA_02767 1.5e-234 ktrB P Potassium
HILOHAJA_02768 3.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
HILOHAJA_02769 2.2e-91 yuaB
HILOHAJA_02770 1.4e-95 yuaC K Belongs to the GbsR family
HILOHAJA_02771 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HILOHAJA_02772 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HILOHAJA_02773 2.3e-107 yuaD
HILOHAJA_02774 3.9e-84 yuaE S DinB superfamily
HILOHAJA_02775 1e-74 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HILOHAJA_02776 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HILOHAJA_02777 2.4e-92 M1-753 M FR47-like protein
HILOHAJA_02778 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)