ORF_ID e_value Gene_name EC_number CAZy COGs Description
HIMEKJLC_00001 1.5e-247 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HIMEKJLC_00002 4.7e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HIMEKJLC_00003 2.2e-34 yaaA S S4 domain protein YaaA
HIMEKJLC_00004 4.3e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HIMEKJLC_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIMEKJLC_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIMEKJLC_00007 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HIMEKJLC_00008 3.5e-89 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HIMEKJLC_00009 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HIMEKJLC_00010 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HIMEKJLC_00011 1.2e-74 rplI J Binds to the 23S rRNA
HIMEKJLC_00012 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HIMEKJLC_00013 1.2e-171 L Transposase and inactivated derivatives IS30 family
HIMEKJLC_00014 1.4e-207 lmrP E Major Facilitator Superfamily
HIMEKJLC_00015 2.3e-59
HIMEKJLC_00018 6.8e-130 K response regulator
HIMEKJLC_00019 0.0 vicK 2.7.13.3 T Histidine kinase
HIMEKJLC_00020 2.6e-236 yycH S YycH protein
HIMEKJLC_00021 8.8e-142 yycI S YycH protein
HIMEKJLC_00022 1.3e-153 vicX 3.1.26.11 S domain protein
HIMEKJLC_00023 4.6e-198 htrA 3.4.21.107 O serine protease
HIMEKJLC_00024 1.5e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HIMEKJLC_00025 1.1e-69 K Transcriptional regulator
HIMEKJLC_00026 3.6e-45 malR K Transcriptional regulator, LacI family
HIMEKJLC_00027 8.3e-106 ysdA CP transmembrane transport
HIMEKJLC_00028 4.4e-11 ysdA CP ABC-type Na efflux pump, permease component
HIMEKJLC_00029 7.8e-70 natA S ABC transporter, ATP-binding protein
HIMEKJLC_00030 3.4e-188 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIMEKJLC_00031 1.3e-78 D Alpha beta
HIMEKJLC_00032 4.9e-81 tlpA2 L Transposase IS200 like
HIMEKJLC_00033 7.1e-239 L transposase, IS605 OrfB family
HIMEKJLC_00034 3.3e-20 D Alpha beta
HIMEKJLC_00035 4.3e-32 D Alpha beta
HIMEKJLC_00036 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMEKJLC_00037 4.2e-217 patA 2.6.1.1 E Aminotransferase
HIMEKJLC_00038 1e-34
HIMEKJLC_00039 0.0 clpL O associated with various cellular activities
HIMEKJLC_00040 5.3e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIMEKJLC_00041 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HIMEKJLC_00042 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HIMEKJLC_00043 2.6e-163 yvgN C Aldo keto reductase
HIMEKJLC_00044 2.8e-288 glpQ 3.1.4.46 C phosphodiesterase
HIMEKJLC_00045 3.9e-65 arsC 1.20.4.1 P Belongs to the ArsC family
HIMEKJLC_00046 1.4e-114 ybhR V ABC transporter
HIMEKJLC_00047 3.1e-58 ybhR V ABC transporter
HIMEKJLC_00048 2.4e-81 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HIMEKJLC_00049 2.4e-19 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HIMEKJLC_00050 1.8e-41 K transcriptional regulator
HIMEKJLC_00051 1.7e-63 L transposase, IS605 OrfB family
HIMEKJLC_00052 6.5e-19 tlpA2 L Transposase IS200 like
HIMEKJLC_00053 5.5e-37 K transcriptional regulator
HIMEKJLC_00054 4.3e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIMEKJLC_00055 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIMEKJLC_00056 6.6e-254 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HIMEKJLC_00057 5.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIMEKJLC_00058 1.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HIMEKJLC_00059 2.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIMEKJLC_00060 6.4e-60 gntT EG gluconate transmembrane transporter activity
HIMEKJLC_00061 7.5e-244 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_00062 9e-47
HIMEKJLC_00063 4.2e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HIMEKJLC_00064 1.6e-258 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HIMEKJLC_00065 5.1e-148 metQ1 P Belongs to the nlpA lipoprotein family
HIMEKJLC_00066 4.4e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIMEKJLC_00067 7.6e-97 metI P ABC transporter permease
HIMEKJLC_00068 9.2e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HIMEKJLC_00069 5.8e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIMEKJLC_00070 3.7e-196 brnQ U Component of the transport system for branched-chain amino acids
HIMEKJLC_00071 2.2e-123 iolS C Aldo keto reductase
HIMEKJLC_00072 1.4e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIMEKJLC_00073 3.6e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMEKJLC_00074 5.3e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
HIMEKJLC_00075 1.8e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMEKJLC_00077 6.5e-19 tlpA2 L Transposase IS200 like
HIMEKJLC_00078 2.3e-237 L transposase, IS605 OrfB family
HIMEKJLC_00079 1.4e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HIMEKJLC_00080 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HIMEKJLC_00081 5.7e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIMEKJLC_00083 7.3e-149 L transposase, IS605 OrfB family
HIMEKJLC_00084 1.2e-222 L Transposase
HIMEKJLC_00085 3.3e-250 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HIMEKJLC_00086 1.4e-80 tlpA2 L Transposase IS200 like
HIMEKJLC_00087 2.7e-238 L transposase, IS605 OrfB family
HIMEKJLC_00088 4.3e-245 cycA E Amino acid permease
HIMEKJLC_00089 3.8e-187 L Helix-turn-helix domain
HIMEKJLC_00090 1.1e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIMEKJLC_00091 6.4e-223 glnP P ABC transporter
HIMEKJLC_00092 8.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIMEKJLC_00093 1.4e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIMEKJLC_00094 4.9e-213 nupG F Nucleoside transporter
HIMEKJLC_00095 7.5e-145 rihC 3.2.2.1 F Nucleoside
HIMEKJLC_00096 3.4e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HIMEKJLC_00097 1.3e-155 noc K Belongs to the ParB family
HIMEKJLC_00098 1.3e-143 spo0J K Belongs to the ParB family
HIMEKJLC_00099 1.7e-30 yyzM S Bacterial protein of unknown function (DUF951)
HIMEKJLC_00100 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIMEKJLC_00101 2.5e-133 XK27_01040 S Protein of unknown function (DUF1129)
HIMEKJLC_00102 9.5e-206 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIMEKJLC_00103 3.1e-160 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HIMEKJLC_00104 8.3e-129 epsB M biosynthesis protein
HIMEKJLC_00105 1.6e-113 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HIMEKJLC_00106 1.9e-138 ywqE 3.1.3.48 GM PHP domain protein
HIMEKJLC_00107 4e-57 capM M Bacterial sugar transferase
HIMEKJLC_00108 4.7e-171 L Transposase and inactivated derivatives IS30 family
HIMEKJLC_00109 1.3e-103 rfbP M Bacterial sugar transferase
HIMEKJLC_00110 8e-216 L Transposase
HIMEKJLC_00111 1.1e-214 L Transposase DDE domain group 1
HIMEKJLC_00112 9.4e-172 L Transposase and inactivated derivatives IS30 family
HIMEKJLC_00113 4.9e-63 cps4F 2.4.1.306 GT4 M Glycosyltransferase Family 4
HIMEKJLC_00114 2.3e-212 tra L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_00115 6.4e-170 L Integrase core domain
HIMEKJLC_00116 2.5e-46 L Transposase
HIMEKJLC_00117 9.3e-47 S polysaccharide biosynthetic process
HIMEKJLC_00118 4.4e-183 L PFAM Integrase catalytic region
HIMEKJLC_00119 5.3e-101 MA20_17390 GT4 M Glycosyl transferases group 1
HIMEKJLC_00120 1e-51
HIMEKJLC_00121 9.2e-54 waaB GT4 M Glycosyl transferases group 1
HIMEKJLC_00123 3e-14 XK27_01125 L PFAM IS66 Orf2 family protein
HIMEKJLC_00124 1.2e-123 L Transposase
HIMEKJLC_00125 2.3e-87 L Transposase
HIMEKJLC_00126 3e-119 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_00127 3.7e-142 L PFAM Integrase catalytic region
HIMEKJLC_00128 5.5e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_00129 3.5e-135 L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_00130 6.2e-32 wcaB 2.3.1.30 E serine acetyltransferase
HIMEKJLC_00131 4.7e-85 L hmm pf00665
HIMEKJLC_00132 4.8e-40 L transposase activity
HIMEKJLC_00133 2.1e-144 L Transposase and inactivated derivatives
HIMEKJLC_00134 8.8e-94 S Cupin superfamily (DUF985)
HIMEKJLC_00135 1e-122 K response regulator
HIMEKJLC_00136 1.7e-207 hpk31 2.7.13.3 T Histidine kinase
HIMEKJLC_00137 2.5e-202 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HIMEKJLC_00138 9.3e-137 azlC E AzlC protein
HIMEKJLC_00139 2e-60 azlD S branched-chain amino acid
HIMEKJLC_00140 2.5e-55 ydeN S Serine hydrolase
HIMEKJLC_00141 1.4e-80 tlpA2 L Transposase IS200 like
HIMEKJLC_00142 6.6e-237 L transposase, IS605 OrfB family
HIMEKJLC_00143 4.4e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HIMEKJLC_00144 6.6e-26 K transcriptional regulator
HIMEKJLC_00145 2.1e-14 K Bacterial regulatory proteins, tetR family
HIMEKJLC_00146 1.1e-163 K AI-2E family transporter
HIMEKJLC_00147 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HIMEKJLC_00148 5.3e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HIMEKJLC_00149 1.5e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIMEKJLC_00150 1.2e-254 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIMEKJLC_00151 3.5e-167 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
HIMEKJLC_00152 1.6e-235 S response to antibiotic
HIMEKJLC_00153 3.2e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HIMEKJLC_00154 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIMEKJLC_00155 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIMEKJLC_00156 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIMEKJLC_00157 4.1e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HIMEKJLC_00158 3.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HIMEKJLC_00159 1.5e-106 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HIMEKJLC_00160 5.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HIMEKJLC_00161 5.8e-241 purD 6.3.4.13 F Belongs to the GARS family
HIMEKJLC_00162 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIMEKJLC_00163 1.1e-222 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HIMEKJLC_00164 1.1e-178
HIMEKJLC_00165 1.1e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HIMEKJLC_00166 9.5e-52 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HIMEKJLC_00167 0.0 copA 3.6.3.54 P P-type ATPase
HIMEKJLC_00168 1.1e-27 EGP Major facilitator Superfamily
HIMEKJLC_00169 1.2e-44 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
HIMEKJLC_00170 5.5e-32 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
HIMEKJLC_00171 9.8e-77
HIMEKJLC_00173 3.1e-10 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HIMEKJLC_00174 7.8e-120 pnb C nitroreductase
HIMEKJLC_00175 4.9e-84 S Alpha/beta hydrolase family
HIMEKJLC_00177 8.7e-29 K Bacterial regulatory helix-turn-helix protein, lysR family
HIMEKJLC_00178 4.3e-10 K Bacterial regulatory helix-turn-helix protein, lysR family
HIMEKJLC_00179 3.3e-47 C Aldo keto reductase
HIMEKJLC_00182 1.7e-16 C Aldo/keto reductase family
HIMEKJLC_00183 1.5e-90 P Cadmium resistance transporter
HIMEKJLC_00184 1.1e-133 L PFAM transposase, IS4 family protein
HIMEKJLC_00185 4.6e-32 ydzE EG spore germination
HIMEKJLC_00187 9.8e-40 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HIMEKJLC_00188 7.7e-236 kgtP EGP Sugar (and other) transporter
HIMEKJLC_00189 5.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HIMEKJLC_00190 9.8e-77
HIMEKJLC_00191 7.9e-49 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMEKJLC_00192 4.2e-43 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HIMEKJLC_00193 2.4e-49 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HIMEKJLC_00194 1.1e-123 C nitroreductase
HIMEKJLC_00195 6.6e-136 E GDSL-like Lipase/Acylhydrolase family
HIMEKJLC_00196 6.7e-53 S Mazg nucleotide pyrophosphohydrolase
HIMEKJLC_00197 3.6e-129 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HIMEKJLC_00198 0.0 pepN 3.4.11.2 E aminopeptidase
HIMEKJLC_00199 2.5e-08 tlpA2 L Transposase IS200 like
HIMEKJLC_00200 4.1e-38 tlpA2 L Transposase IS200 like
HIMEKJLC_00201 2.3e-237 L transposase, IS605 OrfB family
HIMEKJLC_00202 7.5e-69 K Transcriptional regulator
HIMEKJLC_00203 1.4e-84 K Transcriptional regulator
HIMEKJLC_00204 1e-24 phaG GT1 I carboxylic ester hydrolase activity
HIMEKJLC_00205 2.3e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HIMEKJLC_00207 1.1e-153 metQ_4 P Belongs to the nlpA lipoprotein family
HIMEKJLC_00208 5.8e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HIMEKJLC_00209 0.0 helD 3.6.4.12 L DNA helicase
HIMEKJLC_00210 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HIMEKJLC_00211 6.8e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HIMEKJLC_00212 2.5e-186
HIMEKJLC_00213 4.4e-129 cobB K SIR2 family
HIMEKJLC_00214 6.5e-210 norA EGP Major facilitator Superfamily
HIMEKJLC_00215 2.6e-160 yunF F Protein of unknown function DUF72
HIMEKJLC_00216 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIMEKJLC_00217 7.6e-146 tatD L hydrolase, TatD family
HIMEKJLC_00218 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIMEKJLC_00219 6.1e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIMEKJLC_00220 1.4e-158 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HIMEKJLC_00221 5.2e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
HIMEKJLC_00222 3.5e-94 fhuC P ABC transporter
HIMEKJLC_00223 9.4e-128 znuB U ABC 3 transport family
HIMEKJLC_00224 2.2e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HIMEKJLC_00225 5.3e-203 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIMEKJLC_00226 1.4e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIMEKJLC_00227 3e-32
HIMEKJLC_00228 1.2e-141 yxeH S hydrolase
HIMEKJLC_00229 4.3e-266 ywfO S HD domain protein
HIMEKJLC_00230 3.2e-74 ywiB S Domain of unknown function (DUF1934)
HIMEKJLC_00231 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HIMEKJLC_00232 8.9e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIMEKJLC_00233 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIMEKJLC_00234 6e-41 rpmE2 J Ribosomal protein L31
HIMEKJLC_00235 3.3e-29 mdtG EGP Major facilitator Superfamily
HIMEKJLC_00236 1.8e-122 srtA 3.4.22.70 M sortase family
HIMEKJLC_00237 6.9e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIMEKJLC_00238 2.8e-86 lemA S LemA family
HIMEKJLC_00239 2.4e-156 htpX O Belongs to the peptidase M48B family
HIMEKJLC_00240 2.1e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIMEKJLC_00241 9.6e-251 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HIMEKJLC_00242 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIMEKJLC_00243 2.2e-207 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIMEKJLC_00244 1.9e-56 L Toxic component of a toxin-antitoxin (TA) module
HIMEKJLC_00245 4e-113 S (CBS) domain
HIMEKJLC_00246 3.7e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIMEKJLC_00247 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIMEKJLC_00248 1.6e-39 yabO J S4 domain protein
HIMEKJLC_00249 1.5e-56 divIC D Septum formation initiator
HIMEKJLC_00250 3e-87 yabR J RNA binding
HIMEKJLC_00251 2.2e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIMEKJLC_00252 5.9e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HIMEKJLC_00253 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIMEKJLC_00254 5.8e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HIMEKJLC_00255 9.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIMEKJLC_00256 1.2e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HIMEKJLC_00259 9.8e-77
HIMEKJLC_00262 3.1e-50 L Transposase
HIMEKJLC_00263 2.7e-105 L Transposase
HIMEKJLC_00264 3.5e-162 P secondary active sulfate transmembrane transporter activity
HIMEKJLC_00265 2.5e-66 apt 2.4.2.7 F Phosphoribosyl transferase domain
HIMEKJLC_00266 2.7e-252 nox C NADH oxidase
HIMEKJLC_00267 1.6e-59 L hmm pf00665
HIMEKJLC_00268 3.3e-234 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HIMEKJLC_00269 5.4e-220 L Transposase
HIMEKJLC_00270 3e-155 tra L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_00271 8.3e-224 oxlT P Major Facilitator Superfamily
HIMEKJLC_00272 9.8e-39 L Transposase and inactivated derivatives
HIMEKJLC_00273 1.9e-92 L Integrase core domain
HIMEKJLC_00274 1.2e-159 D nuclear chromosome segregation
HIMEKJLC_00275 1.2e-244 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_00276 2.5e-251 dtpT U amino acid peptide transporter
HIMEKJLC_00277 3.5e-157 yjjH S Calcineurin-like phosphoesterase
HIMEKJLC_00280 2.2e-111
HIMEKJLC_00281 3.7e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HIMEKJLC_00282 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
HIMEKJLC_00283 8.5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIMEKJLC_00284 7.5e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HIMEKJLC_00285 0.0 yhgF K Tex-like protein N-terminal domain protein
HIMEKJLC_00286 6.2e-84 ydcK S Belongs to the SprT family
HIMEKJLC_00288 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HIMEKJLC_00289 4e-189 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HIMEKJLC_00290 8.6e-168 mleP2 S Sodium Bile acid symporter family
HIMEKJLC_00291 6.1e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIMEKJLC_00292 2.4e-164 I alpha/beta hydrolase fold
HIMEKJLC_00293 4e-264 pepC 3.4.22.40 E Peptidase C1-like family
HIMEKJLC_00294 2.4e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
HIMEKJLC_00295 1.6e-51 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HIMEKJLC_00296 3.6e-46 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HIMEKJLC_00297 3.5e-54 HA62_12640 S GCN5-related N-acetyl-transferase
HIMEKJLC_00298 1.3e-96 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HIMEKJLC_00299 1.6e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIMEKJLC_00300 1.5e-203 yacL S domain protein
HIMEKJLC_00301 3.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIMEKJLC_00302 7.8e-100 ywlG S Belongs to the UPF0340 family
HIMEKJLC_00303 1.3e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIMEKJLC_00304 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HIMEKJLC_00305 6.4e-134 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIMEKJLC_00306 4.5e-103 sigH K Belongs to the sigma-70 factor family
HIMEKJLC_00307 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HIMEKJLC_00308 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIMEKJLC_00309 2.9e-96 nusG K Participates in transcription elongation, termination and antitermination
HIMEKJLC_00310 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIMEKJLC_00311 9.7e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIMEKJLC_00312 6.6e-243 steT E amino acid
HIMEKJLC_00313 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIMEKJLC_00314 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIMEKJLC_00315 9.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
HIMEKJLC_00316 1.2e-175 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HIMEKJLC_00317 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HIMEKJLC_00318 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HIMEKJLC_00319 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HIMEKJLC_00320 4.7e-244 brnQ U Component of the transport system for branched-chain amino acids
HIMEKJLC_00321 2.1e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIMEKJLC_00322 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIMEKJLC_00323 2e-35 nrdH O Glutaredoxin
HIMEKJLC_00324 6.3e-80 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIMEKJLC_00326 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIMEKJLC_00327 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HIMEKJLC_00328 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIMEKJLC_00329 2.4e-21 S Protein of unknown function (DUF2508)
HIMEKJLC_00330 1.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIMEKJLC_00331 1.3e-51 yaaQ S Cyclic-di-AMP receptor
HIMEKJLC_00332 2.4e-192 holB 2.7.7.7 L DNA polymerase III
HIMEKJLC_00333 1.5e-55 yabA L Involved in initiation control of chromosome replication
HIMEKJLC_00334 8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIMEKJLC_00335 3.3e-146 fat 3.1.2.21 I Acyl-ACP thioesterase
HIMEKJLC_00336 1.1e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HIMEKJLC_00337 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HIMEKJLC_00338 3.1e-170 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HIMEKJLC_00339 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HIMEKJLC_00340 9.1e-145 KT YcbB domain
HIMEKJLC_00341 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HIMEKJLC_00342 3.9e-145 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HIMEKJLC_00343 5.9e-238 arcA 3.5.3.6 E Arginine
HIMEKJLC_00344 2.7e-258 E Arginine ornithine antiporter
HIMEKJLC_00345 1.7e-215 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HIMEKJLC_00346 1.7e-215 arcT 2.6.1.1 E Aminotransferase
HIMEKJLC_00347 6e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HIMEKJLC_00348 1.5e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HIMEKJLC_00349 1.4e-192 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIMEKJLC_00351 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HIMEKJLC_00352 4.1e-72 marR K Transcriptional regulator, MarR family
HIMEKJLC_00353 7e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIMEKJLC_00354 9.4e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIMEKJLC_00355 2.8e-171 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HIMEKJLC_00356 2.7e-129 IQ reductase
HIMEKJLC_00357 6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIMEKJLC_00358 1.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HIMEKJLC_00359 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HIMEKJLC_00360 1.8e-262 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HIMEKJLC_00361 1.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HIMEKJLC_00362 2.3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HIMEKJLC_00363 1.3e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HIMEKJLC_00364 3.5e-90 bioY S BioY family
HIMEKJLC_00365 3.6e-49 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HIMEKJLC_00366 3.6e-114 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HIMEKJLC_00367 0.0 uup S ABC transporter, ATP-binding protein
HIMEKJLC_00368 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HIMEKJLC_00369 7.4e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIMEKJLC_00370 3.4e-289 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIMEKJLC_00371 0.0 ydaO E amino acid
HIMEKJLC_00372 6.4e-38
HIMEKJLC_00373 9e-113 yvyE 3.4.13.9 S YigZ family
HIMEKJLC_00374 1.5e-250 comFA L Helicase C-terminal domain protein
HIMEKJLC_00375 4e-127 comFC S Competence protein
HIMEKJLC_00376 2.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIMEKJLC_00377 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIMEKJLC_00378 4.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIMEKJLC_00379 1.2e-52 KT PspC domain protein
HIMEKJLC_00380 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HIMEKJLC_00381 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HIMEKJLC_00382 3.4e-160 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIMEKJLC_00383 2.9e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HIMEKJLC_00384 6.7e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HIMEKJLC_00385 2e-146 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HIMEKJLC_00386 6.1e-224 mtnE 2.6.1.83 E Aminotransferase
HIMEKJLC_00387 1.7e-187 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIMEKJLC_00388 7.6e-39 yphH S Cupin domain
HIMEKJLC_00389 1.3e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIMEKJLC_00390 1.7e-153 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HIMEKJLC_00391 1.5e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HIMEKJLC_00392 2.9e-81 tlpA2 L Transposase IS200 like
HIMEKJLC_00393 3.2e-239 L transposase, IS605 OrfB family
HIMEKJLC_00394 1.9e-197 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HIMEKJLC_00395 1.4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HIMEKJLC_00396 7.8e-135 cof S haloacid dehalogenase-like hydrolase
HIMEKJLC_00397 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HIMEKJLC_00398 4e-113 yfbR S HD containing hydrolase-like enzyme
HIMEKJLC_00400 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIMEKJLC_00401 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIMEKJLC_00402 5.1e-201
HIMEKJLC_00403 8.6e-159 rapZ S Displays ATPase and GTPase activities
HIMEKJLC_00404 1.7e-184 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HIMEKJLC_00405 2.7e-166 whiA K May be required for sporulation
HIMEKJLC_00406 1.2e-244 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_00407 8.7e-116 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HIMEKJLC_00408 1.7e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIMEKJLC_00412 1.8e-113 L Helix-turn-helix domain
HIMEKJLC_00413 1e-15
HIMEKJLC_00414 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIMEKJLC_00415 1.5e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HIMEKJLC_00416 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIMEKJLC_00417 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIMEKJLC_00418 1.1e-251 yifK E Amino acid permease
HIMEKJLC_00419 4.2e-289 clcA P chloride
HIMEKJLC_00420 4.5e-33 secG U Preprotein translocase
HIMEKJLC_00421 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HIMEKJLC_00422 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HIMEKJLC_00423 5.5e-109 yxjI
HIMEKJLC_00424 5.8e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIMEKJLC_00425 1.6e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HIMEKJLC_00426 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HIMEKJLC_00427 3.3e-89 K Acetyltransferase (GNAT) domain
HIMEKJLC_00428 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
HIMEKJLC_00429 2.9e-165 murB 1.3.1.98 M Cell wall formation
HIMEKJLC_00430 5.2e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIMEKJLC_00431 2.7e-115 ybbR S YbbR-like protein
HIMEKJLC_00432 1.1e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIMEKJLC_00433 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIMEKJLC_00434 3.3e-52
HIMEKJLC_00435 7.1e-211 oatA I Acyltransferase
HIMEKJLC_00436 1.1e-147 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HIMEKJLC_00437 2.4e-75 lytE M Lysin motif
HIMEKJLC_00438 3e-158 MA20_14895 S Conserved hypothetical protein 698
HIMEKJLC_00439 2.7e-163 K LysR substrate binding domain
HIMEKJLC_00440 1.9e-42 manA 5.3.1.8 G mannose-6-phosphate isomerase
HIMEKJLC_00441 2.4e-10 manA 5.3.1.8 G mannose-6-phosphate isomerase
HIMEKJLC_00442 3.9e-148 yitS S EDD domain protein, DegV family
HIMEKJLC_00443 1.2e-88 racA K Domain of unknown function (DUF1836)
HIMEKJLC_00444 1.3e-179 yfeX P Peroxidase
HIMEKJLC_00445 6.5e-19 tlpA2 L Transposase IS200 like
HIMEKJLC_00446 5.1e-237 L transposase, IS605 OrfB family
HIMEKJLC_00447 5.3e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HIMEKJLC_00448 2.3e-121 manY G PTS system
HIMEKJLC_00449 3e-170 manN G system, mannose fructose sorbose family IID component
HIMEKJLC_00450 1.8e-56 S Domain of unknown function (DUF956)
HIMEKJLC_00452 6.7e-125 L PFAM transposase, IS4 family protein
HIMEKJLC_00453 1.2e-100 L PFAM Integrase catalytic region
HIMEKJLC_00454 3.2e-130 K response regulator
HIMEKJLC_00455 3.1e-249 yclK 2.7.13.3 T Histidine kinase
HIMEKJLC_00456 1.9e-150 glcU U sugar transport
HIMEKJLC_00457 8.1e-246 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_00458 3.9e-104 ahpC 1.11.1.15 O Peroxiredoxin
HIMEKJLC_00459 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HIMEKJLC_00460 8.2e-257 pgi 5.3.1.9 G Belongs to the GPI family
HIMEKJLC_00462 3e-84 K GNAT family
HIMEKJLC_00463 9.2e-119 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HIMEKJLC_00464 1.7e-96 ytbE 1.1.1.346 S Aldo keto reductase
HIMEKJLC_00465 4.7e-41 ytbE 1.1.1.346 S Aldo keto reductase
HIMEKJLC_00466 1.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIMEKJLC_00467 5.6e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HIMEKJLC_00469 3.6e-57
HIMEKJLC_00471 3.5e-08
HIMEKJLC_00472 8.8e-78 K Winged helix DNA-binding domain
HIMEKJLC_00473 2.6e-203 lmrA V ABC transporter, ATP-binding protein
HIMEKJLC_00474 4.4e-71 lmrA V ABC transporter, ATP-binding protein
HIMEKJLC_00475 9.9e-161 yfiC V ABC transporter
HIMEKJLC_00476 4.6e-23 yfiC V ABC transporter
HIMEKJLC_00477 3.1e-131 L PFAM transposase, IS4 family protein
HIMEKJLC_00478 1.2e-79 tlpA2 L Transposase IS200 like
HIMEKJLC_00479 1.4e-50 L transposase, IS605 OrfB family
HIMEKJLC_00480 2.7e-171 L transposase, IS605 OrfB family
HIMEKJLC_00481 6.9e-106 yfiC V ABC transporter
HIMEKJLC_00482 6.9e-192 ampC V Beta-lactamase
HIMEKJLC_00483 1.4e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIMEKJLC_00484 8.2e-48
HIMEKJLC_00485 8.3e-139 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HIMEKJLC_00486 3.2e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HIMEKJLC_00487 3.2e-109 tdk 2.7.1.21 F thymidine kinase
HIMEKJLC_00488 5.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIMEKJLC_00489 1.9e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIMEKJLC_00490 8.3e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HIMEKJLC_00491 4.6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HIMEKJLC_00492 3.6e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIMEKJLC_00493 1.2e-184 yibE S overlaps another CDS with the same product name
HIMEKJLC_00494 3.3e-125 yibF S overlaps another CDS with the same product name
HIMEKJLC_00495 4e-174 pyrP F Permease
HIMEKJLC_00496 1.6e-29 pyrP F Permease
HIMEKJLC_00497 1.3e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HIMEKJLC_00498 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIMEKJLC_00499 1.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIMEKJLC_00500 1.7e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIMEKJLC_00501 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIMEKJLC_00502 6.6e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIMEKJLC_00503 4.4e-253 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIMEKJLC_00504 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HIMEKJLC_00505 2.8e-29 S Protein of unknown function (DUF1146)
HIMEKJLC_00506 2.1e-219 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HIMEKJLC_00507 2.6e-183 mbl D Cell shape determining protein MreB Mrl
HIMEKJLC_00508 7.9e-32 S Protein of unknown function (DUF2969)
HIMEKJLC_00509 1.7e-221 rodA D Belongs to the SEDS family
HIMEKJLC_00511 1.4e-181 S Protein of unknown function (DUF2785)
HIMEKJLC_00512 2.2e-215 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HIMEKJLC_00513 3.2e-150 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HIMEKJLC_00514 6.8e-81 usp6 T universal stress protein
HIMEKJLC_00516 8.4e-235 rarA L recombination factor protein RarA
HIMEKJLC_00517 1.7e-84 yueI S Protein of unknown function (DUF1694)
HIMEKJLC_00518 1.3e-75 4.4.1.5 E Glyoxalase
HIMEKJLC_00519 1.2e-132 S Membrane
HIMEKJLC_00520 2.3e-148 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIMEKJLC_00521 5.5e-26 S YjcQ protein
HIMEKJLC_00524 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIMEKJLC_00525 3.7e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HIMEKJLC_00526 3.3e-214 iscS2 2.8.1.7 E Aminotransferase class V
HIMEKJLC_00527 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIMEKJLC_00528 1.6e-209 EG GntP family permease
HIMEKJLC_00529 4e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HIMEKJLC_00530 3.3e-35 M LysM domain
HIMEKJLC_00531 1e-35 L Transposase and inactivated derivatives
HIMEKJLC_00532 2e-152 L Integrase core domain
HIMEKJLC_00533 0.0 mco Q Multicopper oxidase
HIMEKJLC_00534 8e-25
HIMEKJLC_00535 7.9e-37
HIMEKJLC_00536 8.4e-139 L PFAM Integrase catalytic region
HIMEKJLC_00537 3.5e-52 ydbD P Catalase
HIMEKJLC_00538 1.3e-21 ydbD P Catalase
HIMEKJLC_00539 5.2e-224 citP C Na citrate symporter
HIMEKJLC_00540 4.4e-203 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HIMEKJLC_00541 9.4e-172 L Transposase and inactivated derivatives IS30 family
HIMEKJLC_00542 2.1e-10 citR K Transcriptional regulator, contains sigma factor-related N-terminal domain
HIMEKJLC_00543 9.5e-164 L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_00544 9.8e-74 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HIMEKJLC_00546 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIMEKJLC_00547 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIMEKJLC_00548 1.9e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HIMEKJLC_00549 7.9e-114 radC L DNA repair protein
HIMEKJLC_00550 1.2e-180 mreB D cell shape determining protein MreB
HIMEKJLC_00551 1.4e-145 mreC M Involved in formation and maintenance of cell shape
HIMEKJLC_00552 6.6e-93 mreD M rod shape-determining protein MreD
HIMEKJLC_00553 1.4e-108 glnP P ABC transporter permease
HIMEKJLC_00554 1.5e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIMEKJLC_00555 1.3e-159 aatB ET ABC transporter substrate-binding protein
HIMEKJLC_00556 5.6e-231 ymfF S Peptidase M16 inactive domain protein
HIMEKJLC_00557 3.8e-251 ymfH S Peptidase M16
HIMEKJLC_00558 1e-94 ymfM S Helix-turn-helix domain
HIMEKJLC_00559 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIMEKJLC_00560 1.2e-230 cinA 3.5.1.42 S Belongs to the CinA family
HIMEKJLC_00561 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIMEKJLC_00562 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
HIMEKJLC_00563 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIMEKJLC_00564 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIMEKJLC_00565 1.9e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIMEKJLC_00566 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIMEKJLC_00567 1.1e-175 2.4.2.29 F queuine tRNA-ribosyltransferase activity
HIMEKJLC_00568 5.5e-42 yajC U Preprotein translocase
HIMEKJLC_00569 3.4e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HIMEKJLC_00570 7.1e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HIMEKJLC_00571 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIMEKJLC_00572 1.2e-42 yrzL S Belongs to the UPF0297 family
HIMEKJLC_00573 4.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIMEKJLC_00574 5.7e-33 yrzB S Belongs to the UPF0473 family
HIMEKJLC_00575 4.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIMEKJLC_00576 1.4e-90 cvpA S Colicin V production protein
HIMEKJLC_00577 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIMEKJLC_00578 1.1e-52 trxA O Belongs to the thioredoxin family
HIMEKJLC_00579 1.2e-225 clcA_2 P Chloride transporter, ClC family
HIMEKJLC_00580 2.9e-34 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_00581 1.3e-54 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_00582 1.5e-92 yslB S Protein of unknown function (DUF2507)
HIMEKJLC_00583 1.4e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HIMEKJLC_00584 6.8e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HIMEKJLC_00585 2e-94 S Phosphoesterase
HIMEKJLC_00586 1.7e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HIMEKJLC_00587 1.8e-156 ykuT M mechanosensitive ion channel
HIMEKJLC_00588 1e-24 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HIMEKJLC_00589 4.9e-70
HIMEKJLC_00590 3.5e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HIMEKJLC_00591 1.6e-183 ccpA K catabolite control protein A
HIMEKJLC_00592 2.4e-81
HIMEKJLC_00593 6.3e-134 yebC K Transcriptional regulatory protein
HIMEKJLC_00594 4.9e-84 mltD CBM50 M PFAM NLP P60 protein
HIMEKJLC_00595 8.1e-121 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HIMEKJLC_00596 5.5e-225 L Transposase
HIMEKJLC_00597 2.6e-15 L Helix-turn-helix domain
HIMEKJLC_00598 3.3e-166 L PFAM Integrase catalytic region
HIMEKJLC_00599 4.6e-109 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HIMEKJLC_00600 1.3e-176 comGA NU Type II IV secretion system protein
HIMEKJLC_00601 3.3e-157 comGB NU type II secretion system
HIMEKJLC_00602 1.1e-47 comGC U competence protein ComGC
HIMEKJLC_00603 3.7e-15 NU general secretion pathway protein
HIMEKJLC_00605 1.9e-13
HIMEKJLC_00607 4.3e-158 ytxK 2.1.1.72 L N-6 DNA Methylase
HIMEKJLC_00608 1.4e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIMEKJLC_00609 7.7e-109 S Calcineurin-like phosphoesterase
HIMEKJLC_00610 1.2e-97 yutD S Protein of unknown function (DUF1027)
HIMEKJLC_00611 1.9e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HIMEKJLC_00612 1.3e-24 S Protein of unknown function (DUF1461)
HIMEKJLC_00613 7.7e-104 dedA S SNARE-like domain protein
HIMEKJLC_00614 9.8e-77
HIMEKJLC_00634 3.2e-17 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HIMEKJLC_00635 7.8e-241 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_00636 8.6e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIMEKJLC_00637 4.5e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HIMEKJLC_00638 1.8e-203 coiA 3.6.4.12 S Competence protein
HIMEKJLC_00639 1.8e-113 yjbH Q Thioredoxin
HIMEKJLC_00640 3e-122 yjbM 2.7.6.5 S RelA SpoT domain protein
HIMEKJLC_00641 1.5e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIMEKJLC_00642 1.1e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HIMEKJLC_00643 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HIMEKJLC_00644 8.2e-162 rrmA 2.1.1.187 H Methyltransferase
HIMEKJLC_00645 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIMEKJLC_00646 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HIMEKJLC_00647 1.2e-07 S Protein of unknown function (DUF4044)
HIMEKJLC_00648 9.8e-58
HIMEKJLC_00649 1.3e-78 mraZ K Belongs to the MraZ family
HIMEKJLC_00650 1.9e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIMEKJLC_00651 7e-09 ftsL D Cell division protein FtsL
HIMEKJLC_00652 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HIMEKJLC_00653 1.6e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIMEKJLC_00654 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIMEKJLC_00655 1e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIMEKJLC_00656 4.6e-149 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HIMEKJLC_00657 1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HIMEKJLC_00658 2e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIMEKJLC_00659 4.6e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIMEKJLC_00660 6.8e-41 yggT S YGGT family
HIMEKJLC_00661 1.3e-145 ylmH S S4 domain protein
HIMEKJLC_00662 4.8e-112 divIVA D DivIVA domain protein
HIMEKJLC_00664 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIMEKJLC_00665 1.2e-32 cspB K Cold shock protein
HIMEKJLC_00666 2.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HIMEKJLC_00668 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIMEKJLC_00669 1.3e-57 XK27_04120 S Putative amino acid metabolism
HIMEKJLC_00670 5.8e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HIMEKJLC_00671 3.9e-306 S amidohydrolase
HIMEKJLC_00672 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HIMEKJLC_00673 4.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HIMEKJLC_00674 7.1e-124 S Repeat protein
HIMEKJLC_00675 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HIMEKJLC_00676 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIMEKJLC_00677 2.7e-73 spx4 1.20.4.1 P ArsC family
HIMEKJLC_00678 1.7e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HIMEKJLC_00679 2.2e-31 ykzG S Belongs to the UPF0356 family
HIMEKJLC_00680 1.2e-74
HIMEKJLC_00681 1.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIMEKJLC_00682 2.4e-49 yktA S Belongs to the UPF0223 family
HIMEKJLC_00683 8.2e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HIMEKJLC_00684 0.0 typA T GTP-binding protein TypA
HIMEKJLC_00685 1.1e-212 ftsW D Belongs to the SEDS family
HIMEKJLC_00686 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HIMEKJLC_00687 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HIMEKJLC_00688 2.1e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIMEKJLC_00689 2.5e-197 ylbL T Belongs to the peptidase S16 family
HIMEKJLC_00690 7.5e-244 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_00691 6.1e-88 comEA L Competence protein ComEA
HIMEKJLC_00692 1.3e-87 comEB 3.5.4.12 F ComE operon protein 2
HIMEKJLC_00693 0.0 comEC S Competence protein ComEC
HIMEKJLC_00694 5.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HIMEKJLC_00695 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
HIMEKJLC_00696 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIMEKJLC_00697 7.4e-15 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HIMEKJLC_00698 3.1e-142 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HIMEKJLC_00699 6e-58 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HIMEKJLC_00700 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIMEKJLC_00701 1.3e-162 S Tetratricopeptide repeat
HIMEKJLC_00702 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIMEKJLC_00703 2.2e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIMEKJLC_00704 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIMEKJLC_00705 8.9e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HIMEKJLC_00706 8.3e-53 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HIMEKJLC_00708 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIMEKJLC_00709 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIMEKJLC_00710 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIMEKJLC_00711 9.2e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HIMEKJLC_00712 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMEKJLC_00713 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HIMEKJLC_00714 9.1e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIMEKJLC_00715 3.4e-44 S Domain of unknown function (DUF4440)
HIMEKJLC_00716 8.6e-187 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMEKJLC_00717 1.6e-224 L Transposase
HIMEKJLC_00718 1.1e-239 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_00719 1.8e-198 gldA 1.1.1.6 C dehydrogenase
HIMEKJLC_00720 5.8e-126 L Transposase
HIMEKJLC_00721 2.6e-49 L Transposase
HIMEKJLC_00722 2e-20 L Transposase
HIMEKJLC_00723 0.0 asnB 6.3.5.4 E Aluminium induced protein
HIMEKJLC_00724 6.8e-17 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HIMEKJLC_00725 4.3e-13
HIMEKJLC_00726 1.1e-181 scrR3 K Transcriptional regulator, LacI family
HIMEKJLC_00727 1.3e-78 F Nucleoside 2-deoxyribosyltransferase
HIMEKJLC_00728 2e-85
HIMEKJLC_00730 1.2e-224 L Transposase
HIMEKJLC_00731 1.3e-123 L PFAM transposase, IS4 family protein
HIMEKJLC_00733 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HIMEKJLC_00734 1.6e-263 frdC 1.3.5.4 C FAD binding domain
HIMEKJLC_00735 4.7e-45 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIMEKJLC_00736 8.9e-90 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIMEKJLC_00737 1.2e-234 P Sodium:sulfate symporter transmembrane region
HIMEKJLC_00738 7.2e-175 citR K sugar-binding domain protein
HIMEKJLC_00739 1.8e-53 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_00740 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_00741 1.6e-85 tra L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_00742 4.1e-209 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HIMEKJLC_00743 1.8e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HIMEKJLC_00744 5.7e-46 citD C Covalent carrier of the coenzyme of citrate lyase
HIMEKJLC_00745 5.1e-162 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HIMEKJLC_00746 3.3e-286 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HIMEKJLC_00747 1.7e-257 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HIMEKJLC_00748 1.3e-145 ydjP I Alpha/beta hydrolase family
HIMEKJLC_00749 3.5e-15 L PFAM transposase, IS4 family protein
HIMEKJLC_00750 1.8e-105 L PFAM transposase, IS4 family protein
HIMEKJLC_00751 2.6e-191 L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_00752 4.1e-28 L PFAM Integrase catalytic region
HIMEKJLC_00753 0.0 uvrA2 L ABC transporter
HIMEKJLC_00754 1.6e-205 tra L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_00755 2e-169 L Transposase and inactivated derivatives IS30 family
HIMEKJLC_00756 1e-19 L Transposase
HIMEKJLC_00757 3e-125 L Transposase
HIMEKJLC_00758 9.3e-55 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HIMEKJLC_00759 4.3e-70 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HIMEKJLC_00760 5.1e-33 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HIMEKJLC_00761 4.1e-26 yitW S Iron-sulfur cluster assembly protein
HIMEKJLC_00762 5.4e-70 UW LPXTG-motif cell wall anchor domain protein
HIMEKJLC_00763 1.5e-27 lutA C Cysteine-rich domain
HIMEKJLC_00764 6.7e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HIMEKJLC_00765 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIMEKJLC_00766 2.4e-37 ynzC S UPF0291 protein
HIMEKJLC_00767 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
HIMEKJLC_00768 7.3e-115 plsC 2.3.1.51 I Acyltransferase
HIMEKJLC_00769 4e-136 yabB 2.1.1.223 L Methyltransferase small domain
HIMEKJLC_00770 2.3e-47 yazA L GIY-YIG catalytic domain protein
HIMEKJLC_00771 4.7e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
HIMEKJLC_00772 7.1e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIMEKJLC_00773 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HIMEKJLC_00774 4.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIMEKJLC_00775 2.2e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIMEKJLC_00776 1.8e-134 cdsA 2.7.7.41 I Belongs to the CDS family
HIMEKJLC_00777 2.3e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HIMEKJLC_00778 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIMEKJLC_00779 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIMEKJLC_00780 1.4e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_00781 1e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
HIMEKJLC_00782 8.8e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HIMEKJLC_00783 1.3e-205 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HIMEKJLC_00784 3e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HIMEKJLC_00785 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIMEKJLC_00786 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HIMEKJLC_00787 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
HIMEKJLC_00788 1.4e-223 nusA K Participates in both transcription termination and antitermination
HIMEKJLC_00789 1.4e-47 ylxR K Protein of unknown function (DUF448)
HIMEKJLC_00790 4.6e-49 ylxQ J ribosomal protein
HIMEKJLC_00791 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIMEKJLC_00792 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIMEKJLC_00793 6.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIMEKJLC_00794 3.3e-183 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HIMEKJLC_00795 5.4e-248 EGP Major facilitator Superfamily
HIMEKJLC_00796 8.8e-223 L Transposase
HIMEKJLC_00797 1.9e-07 L Helix-turn-helix domain
HIMEKJLC_00798 7.7e-163 tnp L MULE transposase domain
HIMEKJLC_00799 3.4e-43 tnp L MULE transposase domain
HIMEKJLC_00800 5.4e-62
HIMEKJLC_00801 5.1e-190 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIMEKJLC_00802 5.6e-61 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIMEKJLC_00803 0.0 dnaK O Heat shock 70 kDa protein
HIMEKJLC_00804 1e-175 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIMEKJLC_00806 2.4e-34 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HIMEKJLC_00807 1.3e-34 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HIMEKJLC_00808 1.6e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HIMEKJLC_00809 2.7e-71 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HIMEKJLC_00810 5.5e-55 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HIMEKJLC_00811 2.9e-51 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HIMEKJLC_00812 3.7e-199 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HIMEKJLC_00813 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIMEKJLC_00814 1.1e-133 L PFAM transposase, IS4 family protein
HIMEKJLC_00815 3.4e-09
HIMEKJLC_00816 2.2e-111 3.1.3.73 G phosphoglycerate mutase
HIMEKJLC_00817 5.1e-110 C aldo keto reductase
HIMEKJLC_00818 2.8e-199 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HIMEKJLC_00819 2.4e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMEKJLC_00820 3.5e-52 L Transposase and inactivated derivatives IS30 family
HIMEKJLC_00821 1.4e-220 iscS 2.8.1.7 E Aminotransferase class V
HIMEKJLC_00822 2.5e-07 tlpA2 L Transposase IS200 like
HIMEKJLC_00823 2.4e-80 tlpA2 L Transposase IS200 like
HIMEKJLC_00824 3.6e-235 L transposase, IS605 OrfB family
HIMEKJLC_00825 2.6e-98 P Cadmium resistance transporter
HIMEKJLC_00826 2.1e-115 S Protein of unknown function (DUF554)
HIMEKJLC_00827 8.4e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIMEKJLC_00828 5.5e-158 P Belongs to the nlpA lipoprotein family
HIMEKJLC_00829 3.3e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIMEKJLC_00830 9.3e-158 L hmm pf00665
HIMEKJLC_00831 1.5e-66 psiE S Phosphate-starvation-inducible E
HIMEKJLC_00832 5.8e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIMEKJLC_00833 1.7e-45 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HIMEKJLC_00834 7.7e-33 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HIMEKJLC_00835 5.6e-55 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIMEKJLC_00836 7.3e-69 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIMEKJLC_00837 1.2e-29 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HIMEKJLC_00838 4e-90 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HIMEKJLC_00839 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HIMEKJLC_00840 5.2e-93 S integral membrane protein
HIMEKJLC_00841 1.1e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIMEKJLC_00843 2.7e-54
HIMEKJLC_00844 1.8e-181 prmA J Ribosomal protein L11 methyltransferase
HIMEKJLC_00845 2e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HIMEKJLC_00846 1.7e-57
HIMEKJLC_00847 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIMEKJLC_00848 2.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIMEKJLC_00849 1.6e-82 slyA K Transcriptional regulator
HIMEKJLC_00850 2.7e-211 metC1 2.5.1.48, 4.4.1.8 E cystathionine
HIMEKJLC_00851 4.2e-68 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HIMEKJLC_00852 2.4e-43 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HIMEKJLC_00853 3.1e-67 yxeM ET Bacterial periplasmic substrate-binding proteins
HIMEKJLC_00854 9.2e-47 yxeL K acetyltransferase
HIMEKJLC_00855 2.2e-70 yxeN U ABC transporter, permease protein
HIMEKJLC_00856 3.4e-78 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
HIMEKJLC_00857 1.2e-144 3.5.1.47 E Peptidase dimerisation domain
HIMEKJLC_00858 1.1e-171 pcaB 4.3.2.2 F Adenylosuccinate lyase C-terminus
HIMEKJLC_00859 9.7e-90 yxeQ S MmgE/PrpD family
HIMEKJLC_00861 1.7e-111 papP P ABC transporter, permease protein
HIMEKJLC_00862 8.5e-114 P ABC transporter permease
HIMEKJLC_00863 3.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIMEKJLC_00864 6.9e-153 cjaA ET ABC transporter substrate-binding protein
HIMEKJLC_00865 1.4e-136 IQ KR domain
HIMEKJLC_00867 2.6e-211 hom1 1.1.1.3 E Homoserine dehydrogenase
HIMEKJLC_00868 2.5e-155 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HIMEKJLC_00869 3.4e-115 L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_00870 1.8e-82 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HIMEKJLC_00871 1.3e-237 L transposase, IS605 OrfB family
HIMEKJLC_00872 3.8e-66 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HIMEKJLC_00873 1.2e-168 yniA G Phosphotransferase enzyme family
HIMEKJLC_00874 1e-171 lytH 3.5.1.28 M Ami_3
HIMEKJLC_00875 2.3e-156 6.3.1.20 H Lipoate-protein ligase
HIMEKJLC_00876 4.9e-10 6.3.1.20 H Lipoate-protein ligase
HIMEKJLC_00877 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
HIMEKJLC_00878 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HIMEKJLC_00879 1.8e-127 yfeJ 6.3.5.2 F glutamine amidotransferase
HIMEKJLC_00880 1.9e-133 L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_00881 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HIMEKJLC_00882 2.1e-71 yqeY S YqeY-like protein
HIMEKJLC_00883 1.1e-178 phoH T phosphate starvation-inducible protein PhoH
HIMEKJLC_00884 1.8e-78 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIMEKJLC_00885 1.1e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HIMEKJLC_00886 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIMEKJLC_00887 2.9e-156 recO L Involved in DNA repair and RecF pathway recombination
HIMEKJLC_00888 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HIMEKJLC_00889 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HIMEKJLC_00890 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIMEKJLC_00891 1.5e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIMEKJLC_00892 1.2e-42 tnp L MULE transposase domain
HIMEKJLC_00893 4.1e-170 tnp L MULE transposase domain
HIMEKJLC_00894 7.3e-58 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_00895 3e-129 EGP Major facilitator Superfamily
HIMEKJLC_00896 5.6e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HIMEKJLC_00897 8.1e-177 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HIMEKJLC_00898 6.5e-262 lysC 2.7.2.4 E Belongs to the aspartokinase family
HIMEKJLC_00899 9.1e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIMEKJLC_00900 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HIMEKJLC_00901 1.5e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HIMEKJLC_00902 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIMEKJLC_00903 1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIMEKJLC_00904 2.1e-216 patA 2.6.1.1 E Aminotransferase
HIMEKJLC_00905 1.3e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIMEKJLC_00906 1.9e-226 ktrB P Potassium uptake protein
HIMEKJLC_00907 7.5e-118 ktrA P domain protein
HIMEKJLC_00908 1.7e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
HIMEKJLC_00909 8.4e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIMEKJLC_00910 1.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HIMEKJLC_00912 0.0 dnaE 2.7.7.7 L DNA polymerase
HIMEKJLC_00913 9.1e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HIMEKJLC_00914 4.7e-168 cvfB S S1 domain
HIMEKJLC_00915 9.1e-132 xerD D recombinase XerD
HIMEKJLC_00916 3.8e-66 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMEKJLC_00917 6.6e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIMEKJLC_00918 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIMEKJLC_00919 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HIMEKJLC_00920 4.1e-80 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIMEKJLC_00921 6e-199 ypbB 5.1.3.1 S Helix-turn-helix domain
HIMEKJLC_00922 1.9e-275 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HIMEKJLC_00923 9.7e-31 M Lysin motif
HIMEKJLC_00924 1.7e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HIMEKJLC_00925 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
HIMEKJLC_00926 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HIMEKJLC_00927 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIMEKJLC_00928 6.9e-234 S Tetratricopeptide repeat protein
HIMEKJLC_00929 4.7e-165 xerD L Phage integrase, N-terminal SAM-like domain
HIMEKJLC_00930 1.4e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HIMEKJLC_00931 0.0 yfmR S ABC transporter, ATP-binding protein
HIMEKJLC_00932 2.6e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIMEKJLC_00933 2.5e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIMEKJLC_00934 7.7e-109 hlyIII S protein, hemolysin III
HIMEKJLC_00935 7.6e-152 DegV S EDD domain protein, DegV family
HIMEKJLC_00936 1.8e-215 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
HIMEKJLC_00937 5.5e-107 cat S Bacterial transferase hexapeptide (six repeats)
HIMEKJLC_00938 1.1e-167 ypmR E lipolytic protein G-D-S-L family
HIMEKJLC_00939 2.7e-103 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HIMEKJLC_00940 2.6e-35 yozE S Belongs to the UPF0346 family
HIMEKJLC_00941 3.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIMEKJLC_00942 1.4e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIMEKJLC_00943 3.6e-165 dprA LU DNA protecting protein DprA
HIMEKJLC_00944 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIMEKJLC_00945 1.8e-153 D DNA integration
HIMEKJLC_00946 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
HIMEKJLC_00947 5.2e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIMEKJLC_00948 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIMEKJLC_00949 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIMEKJLC_00950 1.5e-94 S Protein of unknown function (DUF1440)
HIMEKJLC_00951 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
HIMEKJLC_00952 2.3e-71 yqkB S Belongs to the HesB IscA family
HIMEKJLC_00953 1.4e-74 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HIMEKJLC_00954 7.7e-91 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HIMEKJLC_00955 1.4e-80 yebR 1.8.4.14 T GAF domain-containing protein
HIMEKJLC_00956 8e-244 U Belongs to the purine-cytosine permease (2.A.39) family
HIMEKJLC_00957 3e-242 codA 3.5.4.1 F cytosine deaminase
HIMEKJLC_00958 0.0 oppD EP Psort location Cytoplasmic, score
HIMEKJLC_00960 2.6e-255 rarA L recombination factor protein RarA
HIMEKJLC_00961 4.1e-87 S Protein of unknown function (DUF554)
HIMEKJLC_00962 6.9e-240 yhjX P Major Facilitator Superfamily
HIMEKJLC_00964 2.9e-18 lmrB EGP Major facilitator Superfamily
HIMEKJLC_00965 9.6e-37 clcA P chloride
HIMEKJLC_00966 1.5e-21 clcA P chloride
HIMEKJLC_00967 7.7e-30 clcA P chloride
HIMEKJLC_00968 2.3e-157 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
HIMEKJLC_00969 7.7e-119 5.1.1.13 M racemase activity, acting on amino acids and derivatives
HIMEKJLC_00970 2.1e-261 arcD E Amino acid permease
HIMEKJLC_00971 2.6e-160 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HIMEKJLC_00972 2e-104 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HIMEKJLC_00973 4.4e-71 yncA 2.3.1.79 S Maltose acetyltransferase
HIMEKJLC_00974 3.9e-90 S Fic/DOC family
HIMEKJLC_00975 1.8e-96 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HIMEKJLC_00976 1.2e-195 EGP Sugar (and other) transporter
HIMEKJLC_00977 3.2e-184 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HIMEKJLC_00978 1e-212 2.6.1.1 E Aminotransferase
HIMEKJLC_00981 2.1e-107 S Phage minor capsid protein 2
HIMEKJLC_00982 8.4e-77 I alpha/beta hydrolase fold
HIMEKJLC_00983 6.3e-96 K Acetyltransferase (GNAT) domain
HIMEKJLC_00986 1.2e-158 S DUF218 domain
HIMEKJLC_00987 2.7e-102 1.1.1.346 C Aldo keto reductase
HIMEKJLC_00988 9.8e-16 1.1.1.346 C Aldo keto reductase
HIMEKJLC_00990 9.9e-80 hmpT S ECF-type riboflavin transporter, S component
HIMEKJLC_00991 4.8e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HIMEKJLC_00992 3.7e-235 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
HIMEKJLC_00993 1.6e-21 ywkB S Membrane transport protein
HIMEKJLC_00994 2.4e-44 ywkB S Membrane transport protein
HIMEKJLC_00995 5.6e-200 xerS L Belongs to the 'phage' integrase family
HIMEKJLC_00996 1.8e-178 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIMEKJLC_00997 3.8e-97 4.4.1.8 E Aminotransferase, class I
HIMEKJLC_00998 1.3e-44 4.4.1.8 E Aminotransferase, class I
HIMEKJLC_00999 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
HIMEKJLC_01000 5.8e-132 C Zinc-binding dehydrogenase
HIMEKJLC_01001 1.7e-100 proW P ABC transporter, permease protein
HIMEKJLC_01002 7.2e-141 proV E ABC transporter, ATP-binding protein
HIMEKJLC_01003 2e-107 proWZ P ABC transporter permease
HIMEKJLC_01004 2.8e-160 proX M ABC transporter, substrate-binding protein, QAT family
HIMEKJLC_01005 2e-74 K Transcriptional regulator
HIMEKJLC_01006 4.2e-74 O OsmC-like protein
HIMEKJLC_01007 7.4e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HIMEKJLC_01008 1.8e-10 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HIMEKJLC_01009 3.6e-23 EGP Major Facilitator Superfamily
HIMEKJLC_01010 4.6e-238 L transposase, IS605 OrfB family
HIMEKJLC_01011 1.3e-37 tlpA2 L Transposase IS200 like
HIMEKJLC_01012 4.5e-124 L Probable transposase
HIMEKJLC_01013 2.3e-85 L Probable transposase
HIMEKJLC_01014 1.1e-24 EGP Major Facilitator Superfamily
HIMEKJLC_01015 1.1e-29 EGP Major Facilitator Superfamily
HIMEKJLC_01017 2.4e-16 C Flavodoxin
HIMEKJLC_01018 1.2e-26 GM NmrA-like family
HIMEKJLC_01019 3.9e-19 S NAD(P)H dehydrogenase (quinone) activity
HIMEKJLC_01020 7.5e-86 glcU U sugar transport
HIMEKJLC_01021 1.1e-49 galR K Transcriptional regulator
HIMEKJLC_01022 3.5e-28 galR K Transcriptional regulator
HIMEKJLC_01023 1.8e-150 tnp L MULE transposase domain
HIMEKJLC_01024 1.3e-48 tnp L MULE transposase domain
HIMEKJLC_01025 3.7e-07
HIMEKJLC_01026 6.5e-50 4.4.1.8 E Aminotransferase, class I
HIMEKJLC_01027 6.7e-67 4.4.1.8 E Aminotransferase, class I
HIMEKJLC_01028 6.2e-37 M Protein of unknown function (DUF3737)
HIMEKJLC_01029 1.3e-221 L Transposase
HIMEKJLC_01030 4.4e-106 L Integrase
HIMEKJLC_01031 1.1e-70 ydjP I Alpha/beta hydrolase family
HIMEKJLC_01032 2.6e-136 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HIMEKJLC_01033 2.1e-09
HIMEKJLC_01034 6.1e-35 doc S Fic/DOC family
HIMEKJLC_01035 8.2e-16 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HIMEKJLC_01036 1.2e-18 L Belongs to the 'phage' integrase family
HIMEKJLC_01037 4.2e-158 tnp L MULE transposase domain
HIMEKJLC_01038 1.6e-42 tnp L MULE transposase domain
HIMEKJLC_01039 4.2e-85 L PFAM Integrase catalytic region
HIMEKJLC_01040 2.1e-200 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HIMEKJLC_01041 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HIMEKJLC_01042 5.5e-61 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HIMEKJLC_01043 1.2e-37 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HIMEKJLC_01044 1.3e-42 G Transporter, major facilitator family protein
HIMEKJLC_01045 5.5e-208 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HIMEKJLC_01046 1.4e-212 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HIMEKJLC_01047 1.4e-167 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HIMEKJLC_01048 1.2e-39 gcvR T Belongs to the UPF0237 family
HIMEKJLC_01049 6e-244 XK27_08635 S UPF0210 protein
HIMEKJLC_01050 2.8e-179 yobV1 K WYL domain
HIMEKJLC_01051 1.6e-67 S pyridoxamine 5-phosphate
HIMEKJLC_01055 1.3e-63
HIMEKJLC_01056 2e-113 yicL EG EamA-like transporter family
HIMEKJLC_01057 2.6e-59 S Domain of unknown function (DUF4352)
HIMEKJLC_01058 0.0 1.3.5.4 C FAD binding domain
HIMEKJLC_01059 8.2e-38 K LysR substrate binding domain
HIMEKJLC_01060 6e-109 K LysR substrate binding domain
HIMEKJLC_01061 8.5e-159 rssA S Phospholipase, patatin family
HIMEKJLC_01062 1.7e-213 phbA 2.3.1.9 I Belongs to the thiolase family
HIMEKJLC_01063 3.1e-177 S AI-2E family transporter
HIMEKJLC_01064 3.2e-60 S membrane transporter protein
HIMEKJLC_01065 3.2e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HIMEKJLC_01066 3e-10 V Beta-lactamase
HIMEKJLC_01067 1.4e-170 V Beta-lactamase
HIMEKJLC_01068 9.2e-228
HIMEKJLC_01070 5.3e-153 S Alpha/beta hydrolase of unknown function (DUF915)
HIMEKJLC_01071 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIMEKJLC_01072 1.3e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HIMEKJLC_01073 2.6e-163 endA F DNA RNA non-specific endonuclease
HIMEKJLC_01074 3.4e-266 pipD E Dipeptidase
HIMEKJLC_01076 2.1e-252 yifK E Amino acid permease
HIMEKJLC_01078 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIMEKJLC_01079 1e-237 N Uncharacterized conserved protein (DUF2075)
HIMEKJLC_01080 1.5e-54 S SNARE associated Golgi protein
HIMEKJLC_01081 6.4e-79 ndk 2.7.4.6 F Belongs to the NDK family
HIMEKJLC_01082 4.1e-98 padR K Virulence activator alpha C-term
HIMEKJLC_01083 5.2e-93 padC Q Phenolic acid decarboxylase
HIMEKJLC_01085 1.4e-217 I transferase activity, transferring acyl groups other than amino-acyl groups
HIMEKJLC_01087 6.3e-143 ET Bacterial periplasmic substrate-binding proteins
HIMEKJLC_01088 1.1e-226 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_01089 7.3e-258 guaD 3.5.4.3 F Amidohydrolase family
HIMEKJLC_01090 7.3e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HIMEKJLC_01091 3.5e-57 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
HIMEKJLC_01092 4e-111 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIMEKJLC_01093 4.7e-49 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
HIMEKJLC_01094 3.2e-89 rmeB K transcriptional regulator, MerR family
HIMEKJLC_01095 3e-131 ybbM S Uncharacterised protein family (UPF0014)
HIMEKJLC_01096 1.1e-110 ybbL S ABC transporter, ATP-binding protein
HIMEKJLC_01097 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HIMEKJLC_01098 9.1e-81 L transposase, IS605 OrfB family
HIMEKJLC_01099 4.7e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_01100 4.2e-210 G Major Facilitator Superfamily
HIMEKJLC_01101 3.1e-153 L hmm pf00665
HIMEKJLC_01102 6.2e-59 L Helix-turn-helix domain
HIMEKJLC_01103 5.9e-57 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HIMEKJLC_01104 0.0 L Type III restriction enzyme, res subunit
HIMEKJLC_01105 2.7e-213 tra L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_01106 4.3e-22 L Type III restriction enzyme, res subunit
HIMEKJLC_01108 2.4e-101 K DNA-templated transcription, initiation
HIMEKJLC_01109 6.2e-59 L Helix-turn-helix domain
HIMEKJLC_01110 8.7e-111 L hmm pf00665
HIMEKJLC_01111 9e-14 L hmm pf00665
HIMEKJLC_01112 2.4e-53 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIMEKJLC_01113 8.3e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIMEKJLC_01114 4.9e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMEKJLC_01115 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
HIMEKJLC_01116 6.7e-146 ubiB S ABC1 family
HIMEKJLC_01117 4.2e-80 ubiB S ABC1 family
HIMEKJLC_01118 6.5e-19 tlpA2 L Transposase IS200 like
HIMEKJLC_01119 7.8e-238 L transposase, IS605 OrfB family
HIMEKJLC_01120 9.1e-47 ubiB S ABC1 family
HIMEKJLC_01121 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
HIMEKJLC_01122 8.8e-170 GK ROK family
HIMEKJLC_01123 3.9e-41
HIMEKJLC_01124 1.4e-78 copY K Copper transport repressor CopY TcrY
HIMEKJLC_01126 1.1e-65 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HIMEKJLC_01130 4.9e-168 mutR K Transcriptional activator, Rgg GadR MutR family
HIMEKJLC_01131 7.7e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HIMEKJLC_01132 6.7e-166 gntT EG Gluconate
HIMEKJLC_01133 2.2e-38 gntT EG Gluconate
HIMEKJLC_01134 8.7e-179 K Transcriptional regulator, LacI family
HIMEKJLC_01135 5.4e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HIMEKJLC_01136 6.6e-93 V VanZ like family
HIMEKJLC_01137 2.9e-263 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HIMEKJLC_01138 2.1e-11 ydgH S MMPL family
HIMEKJLC_01139 1.1e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HIMEKJLC_01140 2.7e-160 hipB K Helix-turn-helix
HIMEKJLC_01141 4.4e-58 yitW S Iron-sulfur cluster assembly protein
HIMEKJLC_01142 5.6e-52 narK P Major Facilitator Superfamily
HIMEKJLC_01143 1.1e-20 narK P Major Facilitator Superfamily
HIMEKJLC_01144 5e-153 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HIMEKJLC_01145 1e-51 tra L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_01146 7.7e-230 ndh 1.6.99.3 C NADH dehydrogenase
HIMEKJLC_01147 8e-54 yitW S Iron-sulfur cluster assembly protein
HIMEKJLC_01148 1.2e-17 M1-755 S Domain of unknown function (DUF1858)
HIMEKJLC_01149 3.8e-154 XK27_04775 S PAS domain
HIMEKJLC_01150 1.8e-92 XK27_04775 S PAS domain
HIMEKJLC_01151 7.3e-122 EG EamA-like transporter family
HIMEKJLC_01152 3e-169 fecB P Periplasmic binding protein
HIMEKJLC_01153 1.2e-271 sufB O assembly protein SufB
HIMEKJLC_01154 1.9e-83 nifU C SUF system FeS assembly protein, NifU family
HIMEKJLC_01155 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HIMEKJLC_01156 7.6e-244 sufD O FeS assembly protein SufD
HIMEKJLC_01157 2.5e-144 sufC O FeS assembly ATPase SufC
HIMEKJLC_01158 1.4e-33 feoA P FeoA domain
HIMEKJLC_01159 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HIMEKJLC_01160 6.7e-23 S Virus attachment protein p12 family
HIMEKJLC_01161 2.1e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HIMEKJLC_01162 6.1e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIMEKJLC_01163 3.3e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMEKJLC_01164 4.6e-216 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
HIMEKJLC_01165 6.2e-88 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HIMEKJLC_01166 1.1e-93 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HIMEKJLC_01167 9.9e-74 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HIMEKJLC_01168 6.7e-81 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HIMEKJLC_01169 1.3e-31 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HIMEKJLC_01170 3.7e-91 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HIMEKJLC_01171 4.2e-103
HIMEKJLC_01172 2.8e-39 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HIMEKJLC_01173 2.8e-124 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HIMEKJLC_01174 2.2e-12 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
HIMEKJLC_01175 2.1e-89 ydiN G Major Facilitator Superfamily
HIMEKJLC_01176 6.1e-100 ydiN G Major Facilitator Superfamily
HIMEKJLC_01178 4.3e-243 dtpT U amino acid peptide transporter
HIMEKJLC_01180 9.6e-152 S Sucrose-6F-phosphate phosphohydrolase
HIMEKJLC_01181 1e-97 1.6.5.2 GM NAD(P)H-binding
HIMEKJLC_01182 1.2e-38 1.6.5.2 GM NAD(P)H-binding
HIMEKJLC_01183 2.7e-157 S Alpha beta hydrolase
HIMEKJLC_01184 9.4e-172 L Transposase and inactivated derivatives IS30 family
HIMEKJLC_01185 1.5e-41 lmrB EGP Major facilitator Superfamily
HIMEKJLC_01186 7e-84 lmrB EGP Major facilitator Superfamily
HIMEKJLC_01187 1.1e-84 lmrB EGP Major facilitator Superfamily
HIMEKJLC_01189 0.0 S Bacterial membrane protein YfhO
HIMEKJLC_01190 3.5e-49
HIMEKJLC_01191 0.0 kup P Transport of potassium into the cell
HIMEKJLC_01193 1.3e-282 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIMEKJLC_01194 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HIMEKJLC_01195 2e-275 yjbQ P TrkA C-terminal domain protein
HIMEKJLC_01196 8e-31 yjbQ P TrkA C-terminal domain protein
HIMEKJLC_01197 2.4e-275 pipD E Dipeptidase
HIMEKJLC_01198 1.7e-146 S Alpha/beta hydrolase of unknown function (DUF915)
HIMEKJLC_01199 3.1e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMEKJLC_01200 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIMEKJLC_01201 2.2e-167 T Calcineurin-like phosphoesterase superfamily domain
HIMEKJLC_01202 5.6e-160 EGP Major facilitator Superfamily
HIMEKJLC_01203 1.1e-199 mdtG EGP Major facilitator Superfamily
HIMEKJLC_01204 3.8e-249 yhdP S Transporter associated domain
HIMEKJLC_01205 4e-210 naiP EGP Major facilitator Superfamily
HIMEKJLC_01206 5.8e-70 K LysR substrate binding domain protein
HIMEKJLC_01207 1.5e-16 K LysR substrate binding domain protein
HIMEKJLC_01208 1.1e-214 E GDSL-like Lipase/Acylhydrolase family
HIMEKJLC_01209 1.3e-193 lplA 6.3.1.20 H Lipoate-protein ligase
HIMEKJLC_01210 2e-258 lpdA 1.8.1.4 C Dehydrogenase
HIMEKJLC_01211 2.5e-199 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIMEKJLC_01212 5.8e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HIMEKJLC_01213 1.8e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HIMEKJLC_01214 1.4e-26 yphJ 4.1.1.44 S decarboxylase
HIMEKJLC_01215 2e-49 azlD E Branched-chain amino acid transport
HIMEKJLC_01216 9.3e-75 azlC E azaleucine resistance protein AzlC
HIMEKJLC_01217 3.1e-30 azlC E azaleucine resistance protein AzlC
HIMEKJLC_01218 3.9e-284 thrC 4.2.3.1 E Threonine synthase
HIMEKJLC_01219 9.5e-231 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HIMEKJLC_01220 1.2e-155 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIMEKJLC_01221 1e-98 K Acetyltransferase (GNAT) domain
HIMEKJLC_01222 2.9e-111 ylbE GM NAD(P)H-binding
HIMEKJLC_01223 1.2e-115 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIMEKJLC_01224 1.4e-133 S Belongs to the UPF0246 family
HIMEKJLC_01225 4.6e-98
HIMEKJLC_01226 5.5e-161 degV S EDD domain protein, DegV family
HIMEKJLC_01227 0.0 FbpA K Fibronectin-binding protein
HIMEKJLC_01228 4.3e-125 L PFAM transposase, IS4 family protein
HIMEKJLC_01229 1e-85 2.5.1.74 H UbiA prenyltransferase family
HIMEKJLC_01230 1.6e-49 S Virulence-associated protein E
HIMEKJLC_01231 2.1e-11 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMEKJLC_01232 4.4e-19 S Enoyl-(Acyl carrier protein) reductase
HIMEKJLC_01233 7.9e-163 K Bacterial regulatory helix-turn-helix protein, lysR family
HIMEKJLC_01234 9.8e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HIMEKJLC_01235 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HIMEKJLC_01236 2.6e-205 carA 6.3.5.5 F Belongs to the CarA family
HIMEKJLC_01237 2.2e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIMEKJLC_01238 2.5e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIMEKJLC_01239 1.4e-69 esbA S Family of unknown function (DUF5322)
HIMEKJLC_01240 1.6e-67 rnhA 3.1.26.4 L Ribonuclease HI
HIMEKJLC_01241 5.3e-107 XK27_02070 S Nitroreductase family
HIMEKJLC_01242 4e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
HIMEKJLC_01243 1.2e-118 yecS E ABC transporter permease
HIMEKJLC_01244 4.2e-35 M Glycosyltransferase like family 2
HIMEKJLC_01245 4.6e-51 L Integrase core domain
HIMEKJLC_01246 3.7e-93 L Integrase core domain
HIMEKJLC_01248 7.5e-272 nylA 3.5.1.4 J Belongs to the amidase family
HIMEKJLC_01249 1.2e-128 arcD S C4-dicarboxylate anaerobic carrier
HIMEKJLC_01250 2.7e-238 L transposase, IS605 OrfB family
HIMEKJLC_01251 5.5e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HIMEKJLC_01252 8.9e-83 F Hydrolase, NUDIX family
HIMEKJLC_01253 1.1e-209 S Type IV secretion-system coupling protein DNA-binding domain
HIMEKJLC_01254 0.0 tetP J elongation factor G
HIMEKJLC_01255 4.4e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HIMEKJLC_01256 5.1e-110 ypsA S Belongs to the UPF0398 family
HIMEKJLC_01257 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HIMEKJLC_01258 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HIMEKJLC_01259 7.6e-158 EG EamA-like transporter family
HIMEKJLC_01260 4e-192 C Aldo keto reductase family protein
HIMEKJLC_01261 4.8e-121 ypuA S Protein of unknown function (DUF1002)
HIMEKJLC_01262 4.7e-134 dnaD L DnaD domain protein
HIMEKJLC_01263 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HIMEKJLC_01264 4.7e-88 ypmB S Protein conserved in bacteria
HIMEKJLC_01265 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HIMEKJLC_01266 8.4e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HIMEKJLC_01267 5.3e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HIMEKJLC_01268 5.6e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HIMEKJLC_01269 1.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HIMEKJLC_01270 9.5e-96 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_01271 2.3e-103 pstA P Phosphate transport system permease protein PstA
HIMEKJLC_01272 2.4e-98 pstC P probably responsible for the translocation of the substrate across the membrane
HIMEKJLC_01273 2.2e-90 pstS P Phosphate
HIMEKJLC_01274 4.9e-226 L transposase, IS605 OrfB family
HIMEKJLC_01275 1.6e-42 L Transposase IS200 like
HIMEKJLC_01276 1e-270 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HIMEKJLC_01277 2.3e-153 yitU 3.1.3.104 S hydrolase
HIMEKJLC_01278 1.2e-166 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIMEKJLC_01279 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HIMEKJLC_01280 2.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIMEKJLC_01281 1.6e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIMEKJLC_01282 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HIMEKJLC_01283 5.5e-34 ycsI S Protein of unknown function (DUF1445)
HIMEKJLC_01284 7.3e-46 L Transposase
HIMEKJLC_01285 3.8e-170 L Integrase core domain
HIMEKJLC_01286 1.6e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HIMEKJLC_01287 1.5e-194 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HIMEKJLC_01288 5.2e-124 cas4 3.1.12.1 L Domain of unknown function DUF83
HIMEKJLC_01289 2.4e-161 csd2 L CRISPR-associated protein Cas7
HIMEKJLC_01290 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
HIMEKJLC_01291 3.7e-142 cas5d S CRISPR-associated protein (Cas_Cas5)
HIMEKJLC_01292 0.0 cas3 L Type III restriction enzyme, res subunit
HIMEKJLC_01293 8e-108 tnp L MULE transposase domain
HIMEKJLC_01294 2.7e-213 tra L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_01295 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIMEKJLC_01296 1.7e-260 yfnA E Amino Acid
HIMEKJLC_01297 2.7e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HIMEKJLC_01298 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIMEKJLC_01299 5.4e-40 ylqC S Belongs to the UPF0109 family
HIMEKJLC_01300 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HIMEKJLC_01301 9.2e-40 phoU P Plays a role in the regulation of phosphate uptake
HIMEKJLC_01302 5.2e-223 L Transposase
HIMEKJLC_01303 4.9e-122 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_01304 5.8e-37 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_01305 9.5e-97 G Belongs to the carbohydrate kinase PfkB family
HIMEKJLC_01306 2.5e-177 F Belongs to the purine-cytosine permease (2.A.39) family
HIMEKJLC_01307 3.5e-148 yegU O ADP-ribosylglycohydrolase
HIMEKJLC_01308 1.7e-96 L PFAM Integrase catalytic region
HIMEKJLC_01309 1.9e-103 pncA Q Isochorismatase family
HIMEKJLC_01310 2.9e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIMEKJLC_01311 4.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
HIMEKJLC_01312 9.9e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIMEKJLC_01313 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HIMEKJLC_01314 1e-186 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIMEKJLC_01315 0.0 smc D Required for chromosome condensation and partitioning
HIMEKJLC_01316 5.2e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIMEKJLC_01317 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIMEKJLC_01318 2.6e-162 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HIMEKJLC_01319 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIMEKJLC_01320 1.9e-303 yloV S DAK2 domain fusion protein YloV
HIMEKJLC_01321 3.6e-58 asp S Asp23 family, cell envelope-related function
HIMEKJLC_01322 7.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HIMEKJLC_01323 7.5e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
HIMEKJLC_01324 3.3e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HIMEKJLC_01325 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HIMEKJLC_01326 0.0 KLT serine threonine protein kinase
HIMEKJLC_01327 1.4e-130 stp 3.1.3.16 T phosphatase
HIMEKJLC_01328 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIMEKJLC_01329 8.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIMEKJLC_01330 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIMEKJLC_01331 8e-219 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIMEKJLC_01332 2.1e-45 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIMEKJLC_01333 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HIMEKJLC_01334 3.3e-15
HIMEKJLC_01335 8.6e-80 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_01336 8.3e-307 recN L May be involved in recombinational repair of damaged DNA
HIMEKJLC_01337 6.2e-76 argR K Regulates arginine biosynthesis genes
HIMEKJLC_01338 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HIMEKJLC_01339 1.4e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIMEKJLC_01340 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIMEKJLC_01341 2.5e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIMEKJLC_01342 1.9e-158 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIMEKJLC_01343 4.9e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIMEKJLC_01344 4.1e-72 yqhY S Asp23 family, cell envelope-related function
HIMEKJLC_01345 8.3e-204 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HIMEKJLC_01346 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HIMEKJLC_01347 9e-53 ysxB J Cysteine protease Prp
HIMEKJLC_01348 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HIMEKJLC_01349 1.8e-113 K Transcriptional regulator
HIMEKJLC_01352 5.7e-14 S peptidoglycan catabolic process
HIMEKJLC_01353 1.2e-22 S Predicted membrane protein (DUF2335)
HIMEKJLC_01355 1.3e-07 S N-acetylmuramoyl-L-alanine amidase activity
HIMEKJLC_01356 1e-51 V Abi-like protein
HIMEKJLC_01357 7.4e-64 3.4.21.88 K Peptidase S24-like
HIMEKJLC_01358 1e-28 S Psort location CytoplasmicMembrane, score
HIMEKJLC_01359 8.8e-59
HIMEKJLC_01361 2.5e-15
HIMEKJLC_01362 2.6e-18 S sequence-specific DNA binding
HIMEKJLC_01364 2.5e-95 kcsA P Ion transport protein
HIMEKJLC_01365 1.9e-225 L Transposase
HIMEKJLC_01366 2.7e-17
HIMEKJLC_01367 2.4e-153 S Phage integrase family
HIMEKJLC_01368 1.3e-31 S Phage integrase family
HIMEKJLC_01369 6.6e-93 dut S Protein conserved in bacteria
HIMEKJLC_01370 1.3e-176
HIMEKJLC_01371 1.6e-147
HIMEKJLC_01372 4.7e-13
HIMEKJLC_01373 3.9e-259 glnA 6.3.1.2 E glutamine synthetase
HIMEKJLC_01374 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIMEKJLC_01375 1.4e-23 WQ51_02665 S Protein of unknown function (DUF3042)
HIMEKJLC_01376 3.9e-72 yqhL P Rhodanese-like protein
HIMEKJLC_01377 1.4e-178 glk 2.7.1.2 G Glucokinase
HIMEKJLC_01378 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HIMEKJLC_01379 1.1e-113 gluP 3.4.21.105 S Peptidase, S54 family
HIMEKJLC_01380 2.4e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIMEKJLC_01381 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HIMEKJLC_01382 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HIMEKJLC_01383 0.0 S membrane
HIMEKJLC_01384 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIMEKJLC_01385 1.2e-115 udk 2.7.1.48 F Cytidine monophosphokinase
HIMEKJLC_01386 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIMEKJLC_01387 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIMEKJLC_01388 7.8e-60 yodB K Transcriptional regulator, HxlR family
HIMEKJLC_01389 1.6e-88 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIMEKJLC_01390 9.8e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIMEKJLC_01391 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HIMEKJLC_01392 9.4e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIMEKJLC_01393 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HIMEKJLC_01394 1.6e-233 V MatE
HIMEKJLC_01395 3.4e-280 arlS 2.7.13.3 T Histidine kinase
HIMEKJLC_01396 5.6e-121 K response regulator
HIMEKJLC_01397 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HIMEKJLC_01398 1.5e-95 yceD S Uncharacterized ACR, COG1399
HIMEKJLC_01399 6e-213 ylbM S Belongs to the UPF0348 family
HIMEKJLC_01400 1.5e-138 yqeM Q Methyltransferase
HIMEKJLC_01401 3.9e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIMEKJLC_01402 2.1e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HIMEKJLC_01403 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIMEKJLC_01404 2.6e-49 yhbY J RNA-binding protein
HIMEKJLC_01405 7.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
HIMEKJLC_01406 1.1e-95 yqeG S HAD phosphatase, family IIIA
HIMEKJLC_01407 2e-24 yoaK S Protein of unknown function (DUF1275)
HIMEKJLC_01408 3.2e-19 yoaK S Protein of unknown function (DUF1275)
HIMEKJLC_01409 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIMEKJLC_01410 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HIMEKJLC_01411 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIMEKJLC_01412 5.7e-172 dnaI L Primosomal protein DnaI
HIMEKJLC_01413 1e-251 dnaB L replication initiation and membrane attachment
HIMEKJLC_01414 1.9e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIMEKJLC_01415 8.7e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIMEKJLC_01416 2.1e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HIMEKJLC_01417 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIMEKJLC_01418 6.5e-139 aroD S Serine hydrolase (FSH1)
HIMEKJLC_01419 1.8e-114 ybhL S Belongs to the BI1 family
HIMEKJLC_01420 4.2e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HIMEKJLC_01421 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIMEKJLC_01422 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HIMEKJLC_01423 2.1e-57 ytzB S Small secreted protein
HIMEKJLC_01424 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIMEKJLC_01425 1e-210 ecsB U ABC transporter
HIMEKJLC_01426 2.3e-133 ecsA V ABC transporter, ATP-binding protein
HIMEKJLC_01427 1.4e-77 hit FG histidine triad
HIMEKJLC_01429 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HIMEKJLC_01430 7.5e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIMEKJLC_01431 9.8e-56 yheA S Belongs to the UPF0342 family
HIMEKJLC_01432 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HIMEKJLC_01433 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HIMEKJLC_01435 1.7e-36
HIMEKJLC_01437 1e-199 folP 2.5.1.15 H dihydropteroate synthase
HIMEKJLC_01438 1.4e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HIMEKJLC_01439 9.8e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HIMEKJLC_01440 3.4e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HIMEKJLC_01441 9.2e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HIMEKJLC_01442 3.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HIMEKJLC_01443 4e-119 S CAAX protease self-immunity
HIMEKJLC_01444 4.2e-181 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HIMEKJLC_01445 1.8e-110
HIMEKJLC_01446 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
HIMEKJLC_01447 9.1e-161 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIMEKJLC_01448 1.4e-105 S Putative peptidoglycan binding domain
HIMEKJLC_01449 6.2e-235 L transposase, IS605 OrfB family
HIMEKJLC_01450 1.6e-80 S Putative peptidoglycan binding domain
HIMEKJLC_01451 5.7e-36 S Putative peptidoglycan binding domain
HIMEKJLC_01452 3.3e-86 uspA T Belongs to the universal stress protein A family
HIMEKJLC_01453 1.5e-274 pepV 3.5.1.18 E dipeptidase PepV
HIMEKJLC_01454 4e-156 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIMEKJLC_01455 3.6e-61 3.2.1.23 S Domain of unknown function DUF302
HIMEKJLC_01456 2.6e-297 ytgP S Polysaccharide biosynthesis protein
HIMEKJLC_01457 2.2e-41
HIMEKJLC_01458 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIMEKJLC_01459 4.1e-127 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
HIMEKJLC_01460 4.4e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HIMEKJLC_01461 3.7e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HIMEKJLC_01462 3.6e-246 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_01463 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIMEKJLC_01464 8.5e-51
HIMEKJLC_01465 3.6e-27 tag 3.2.2.20 L glycosylase
HIMEKJLC_01466 2.3e-233 EGP Major facilitator Superfamily
HIMEKJLC_01467 7.4e-85 perR P Belongs to the Fur family
HIMEKJLC_01468 2e-247 cycA E Amino acid permease
HIMEKJLC_01469 4e-22
HIMEKJLC_01473 2.4e-124 K Transcriptional regulator, TetR family
HIMEKJLC_01474 7e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HIMEKJLC_01475 2.4e-84 ykhA 3.1.2.20 I Thioesterase superfamily
HIMEKJLC_01476 1.8e-65 lytE M LysM domain protein
HIMEKJLC_01478 7.2e-200 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HIMEKJLC_01479 1.3e-235 F Permease
HIMEKJLC_01480 1.9e-158 sufD O Uncharacterized protein family (UPF0051)
HIMEKJLC_01481 3.1e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HIMEKJLC_01482 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HIMEKJLC_01483 7.6e-110 XK27_05795 P ABC transporter permease
HIMEKJLC_01484 1.5e-141 ET Bacterial periplasmic substrate-binding proteins
HIMEKJLC_01485 5e-11 qacC P COG2076 Membrane transporters of cations and cationic drugs
HIMEKJLC_01487 3e-07 K Bacterial regulatory proteins, tetR family
HIMEKJLC_01488 6.9e-189 L Helix-turn-helix domain
HIMEKJLC_01498 1.3e-76
HIMEKJLC_01501 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
HIMEKJLC_01502 4.7e-180 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIMEKJLC_01503 1.5e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
HIMEKJLC_01504 2.5e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HIMEKJLC_01505 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIMEKJLC_01506 3e-38 ptsH G phosphocarrier protein HPR
HIMEKJLC_01508 0.0 clpE O Belongs to the ClpA ClpB family
HIMEKJLC_01509 2.4e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
HIMEKJLC_01510 7.8e-108 pncA Q Isochorismatase family
HIMEKJLC_01511 4.1e-259 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIMEKJLC_01512 8.4e-97 S Pfam:DUF3816
HIMEKJLC_01513 2.5e-140 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HIMEKJLC_01514 3.9e-134 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIMEKJLC_01515 1.2e-160 EG EamA-like transporter family
HIMEKJLC_01516 2.7e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
HIMEKJLC_01518 2.3e-13
HIMEKJLC_01519 1.7e-154 V ABC transporter, ATP-binding protein
HIMEKJLC_01520 3.8e-63 gntR1 K Transcriptional regulator, GntR family
HIMEKJLC_01521 1.8e-170 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIMEKJLC_01522 1.9e-88 S Bacterial membrane protein, YfhO
HIMEKJLC_01523 1e-101 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HIMEKJLC_01524 1.3e-95 M transferase activity, transferring glycosyl groups
HIMEKJLC_01525 2.7e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HIMEKJLC_01526 5.9e-164 ykoT GT2 M Glycosyl transferase family 2
HIMEKJLC_01527 8.7e-140 yueF S AI-2E family transporter
HIMEKJLC_01528 1.4e-159 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HIMEKJLC_01529 8.1e-09
HIMEKJLC_01530 7.8e-65 M repeat protein
HIMEKJLC_01531 2.7e-100 S hydrolase
HIMEKJLC_01532 4.5e-263 npr 1.11.1.1 C NADH oxidase
HIMEKJLC_01533 4.2e-200 L Transposase
HIMEKJLC_01534 1.1e-10 L Transposase
HIMEKJLC_01535 2.4e-206 M domain protein
HIMEKJLC_01536 9.2e-52 L Transposase
HIMEKJLC_01537 9.4e-172 L Transposase and inactivated derivatives IS30 family
HIMEKJLC_01538 2e-58 acmD M repeat protein
HIMEKJLC_01539 2e-72 S enterobacterial common antigen metabolic process
HIMEKJLC_01540 1.1e-203 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HIMEKJLC_01541 2.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
HIMEKJLC_01542 1e-44 M biosynthesis protein
HIMEKJLC_01543 2.1e-94 cps3F
HIMEKJLC_01544 6.2e-145 cps1D M Domain of unknown function (DUF4422)
HIMEKJLC_01545 3e-33 rfbP M Bacterial sugar transferase
HIMEKJLC_01546 2.5e-23 rfbP M Bacterial sugar transferase
HIMEKJLC_01547 1.7e-28 recX 2.4.1.337 GT4 S Regulatory protein RecX
HIMEKJLC_01548 1.7e-48 recX 2.4.1.337 GT4 S Regulatory protein RecX
HIMEKJLC_01549 2.8e-24 recX 2.4.1.337 GT4 S Regulatory protein RecX
HIMEKJLC_01550 1.1e-09 recX 2.4.1.337 GT4 S Regulatory protein RecX
HIMEKJLC_01552 3.8e-31 S Protein of unknown function (DUF2922)
HIMEKJLC_01553 2.3e-138 yihY S Belongs to the UPF0761 family
HIMEKJLC_01554 1.9e-65 XK27_08315 M Sulfatase
HIMEKJLC_01555 9e-47 XK27_08315 M Sulfatase
HIMEKJLC_01556 8.7e-237 L transposase, IS605 OrfB family
HIMEKJLC_01557 2.9e-81 tlpA2 L Transposase IS200 like
HIMEKJLC_01558 1.2e-65 XK27_08315 M Sulfatase
HIMEKJLC_01559 1.4e-166 map 3.4.11.18 E Methionine Aminopeptidase
HIMEKJLC_01560 8.5e-78 fld C Flavodoxin
HIMEKJLC_01561 3e-75 gtcA S Teichoic acid glycosylation protein
HIMEKJLC_01563 1.5e-231 yfmL 3.6.4.13 L DEAD DEAH box helicase
HIMEKJLC_01564 6.4e-190 mocA S Oxidoreductase
HIMEKJLC_01565 4.9e-63 S Domain of unknown function (DUF4828)
HIMEKJLC_01566 4.9e-102 yvdD 3.2.2.10 S Belongs to the LOG family
HIMEKJLC_01567 1.1e-159 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HIMEKJLC_01568 2.2e-287 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HIMEKJLC_01569 8e-140 S NADPH-dependent FMN reductase
HIMEKJLC_01570 7.8e-34 yneR S Belongs to the HesB IscA family
HIMEKJLC_01571 1.8e-303 ybiT S ABC transporter, ATP-binding protein
HIMEKJLC_01572 1.5e-188 L Helix-turn-helix domain
HIMEKJLC_01573 1.7e-51 dps P Belongs to the Dps family
HIMEKJLC_01574 3.3e-103
HIMEKJLC_01575 1.9e-183 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HIMEKJLC_01576 1.4e-101 K helix_turn_helix multiple antibiotic resistance protein
HIMEKJLC_01577 1e-64 fsr EGP Major Facilitator Superfamily
HIMEKJLC_01578 4.7e-47 fsr EGP Major Facilitator Superfamily
HIMEKJLC_01579 4.6e-99 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIMEKJLC_01580 2.3e-102 S CAAX protease self-immunity
HIMEKJLC_01582 5.7e-113 Q Methyltransferase domain
HIMEKJLC_01583 1.8e-23 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HIMEKJLC_01584 1.6e-38 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HIMEKJLC_01585 5.9e-49 K 2 iron, 2 sulfur cluster binding
HIMEKJLC_01586 0.0 mco Q Multicopper oxidase
HIMEKJLC_01587 1.2e-80 S Aminoacyl-tRNA editing domain
HIMEKJLC_01588 3.5e-74 ddaH 3.5.3.18 E Amidinotransferase
HIMEKJLC_01590 1.4e-190 nhaC C Na H antiporter NhaC
HIMEKJLC_01591 3.2e-144 S Oxidoreductase family, NAD-binding Rossmann fold
HIMEKJLC_01592 1.7e-237 L transposase, IS605 OrfB family
HIMEKJLC_01594 1.1e-177 S Phosphotransferase system, EIIC
HIMEKJLC_01595 1.2e-23 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HIMEKJLC_01596 7.2e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HIMEKJLC_01597 1.1e-110 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIMEKJLC_01598 9.2e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HIMEKJLC_01599 5.2e-07
HIMEKJLC_01600 1.1e-62 yjbR S YjbR
HIMEKJLC_01601 1.5e-104 S Sel1-like repeats.
HIMEKJLC_01602 3e-218 tnp L MULE transposase domain
HIMEKJLC_01604 3.3e-217 yceI EGP Major facilitator Superfamily
HIMEKJLC_01605 4e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
HIMEKJLC_01606 7.3e-39 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_01607 2.7e-224 L Transposase
HIMEKJLC_01608 3.1e-46 tnp2PF3 L manually curated
HIMEKJLC_01609 9.2e-182 nifS 2.8.1.7 E DegT/DnrJ/EryC1/StrS aminotransferase family
HIMEKJLC_01610 2.7e-202 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HIMEKJLC_01611 3.9e-268 nadB 1.3.5.4, 1.4.3.16 H L-aspartate oxidase
HIMEKJLC_01612 0.0 lacL 3.2.1.23 G hydrolase activity, hydrolyzing O-glycosyl compounds
HIMEKJLC_01613 5e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HIMEKJLC_01614 4e-58 L Helix-turn-helix domain
HIMEKJLC_01615 8.1e-154 L hmm pf00665
HIMEKJLC_01616 1.2e-171 L Transposase and inactivated derivatives IS30 family
HIMEKJLC_01617 9.6e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HIMEKJLC_01618 7.3e-101 S Phage capsid family
HIMEKJLC_01619 2.2e-39 S Phage gp6-like head-tail connector protein
HIMEKJLC_01620 4e-60 S Phage head-tail joining protein
HIMEKJLC_01621 7.9e-62 S Bacteriophage holin family
HIMEKJLC_01622 2.8e-133 M Glycosyl hydrolases family 25
HIMEKJLC_01623 1.3e-29
HIMEKJLC_01624 4e-290 L Recombinase zinc beta ribbon domain
HIMEKJLC_01625 4.4e-294 L Recombinase
HIMEKJLC_01626 5.3e-40 K LytTr DNA-binding domain
HIMEKJLC_01627 5.1e-30 S Protein of unknown function (DUF3021)
HIMEKJLC_01628 4.8e-63 S Domain of unknown function (DUF3841)
HIMEKJLC_01629 1.1e-133 L PFAM transposase, IS4 family protein
HIMEKJLC_01630 1.2e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIMEKJLC_01631 9.6e-186 yegS 2.7.1.107 G Lipid kinase
HIMEKJLC_01632 3.3e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIMEKJLC_01633 1.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIMEKJLC_01634 6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIMEKJLC_01635 1.6e-165 camS S sex pheromone
HIMEKJLC_01636 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIMEKJLC_01637 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HIMEKJLC_01638 5.3e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HIMEKJLC_01639 8e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIMEKJLC_01640 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HIMEKJLC_01641 1.2e-138 IQ reductase
HIMEKJLC_01642 1.4e-30 S interspecies interaction between organisms
HIMEKJLC_01643 1.6e-39 S interspecies interaction between organisms
HIMEKJLC_01644 2.7e-238 L transposase, IS605 OrfB family
HIMEKJLC_01645 1.7e-81 tlpA2 L Transposase IS200 like
HIMEKJLC_01646 6.6e-31 S interspecies interaction between organisms
HIMEKJLC_01647 4e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_01648 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HIMEKJLC_01649 3.4e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIMEKJLC_01650 2.2e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIMEKJLC_01651 3.5e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMEKJLC_01652 4.4e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMEKJLC_01653 1.3e-148 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMEKJLC_01654 2.8e-61 rplQ J Ribosomal protein L17
HIMEKJLC_01655 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMEKJLC_01656 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIMEKJLC_01657 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIMEKJLC_01658 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HIMEKJLC_01659 1.3e-31 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIMEKJLC_01660 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIMEKJLC_01661 1.7e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIMEKJLC_01662 2.1e-65 rplO J Binds to the 23S rRNA
HIMEKJLC_01663 2.5e-23 rpmD J Ribosomal protein L30
HIMEKJLC_01664 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIMEKJLC_01665 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIMEKJLC_01666 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIMEKJLC_01667 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIMEKJLC_01668 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIMEKJLC_01669 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIMEKJLC_01670 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIMEKJLC_01671 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIMEKJLC_01672 1.1e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIMEKJLC_01673 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
HIMEKJLC_01674 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIMEKJLC_01675 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIMEKJLC_01676 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIMEKJLC_01677 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIMEKJLC_01678 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIMEKJLC_01679 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIMEKJLC_01680 8.8e-105 rplD J Forms part of the polypeptide exit tunnel
HIMEKJLC_01681 9.6e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIMEKJLC_01682 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HIMEKJLC_01683 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HIMEKJLC_01684 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HIMEKJLC_01685 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIMEKJLC_01686 2.1e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
HIMEKJLC_01687 5.6e-98 ykiI
HIMEKJLC_01688 2.3e-18 ykiI
HIMEKJLC_01689 1.8e-72 ykiI
HIMEKJLC_01690 1.2e-134 puuD S peptidase C26
HIMEKJLC_01691 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMEKJLC_01692 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMEKJLC_01693 5.8e-106 K Bacterial regulatory proteins, tetR family
HIMEKJLC_01694 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HIMEKJLC_01695 5.3e-78 ctsR K Belongs to the CtsR family
HIMEKJLC_01696 1e-63 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_01697 3.1e-159 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_01698 5.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
HIMEKJLC_01699 1.3e-131 XK27_07210 6.1.1.6 S B3 4 domain
HIMEKJLC_01700 2.3e-117 J 2'-5' RNA ligase superfamily
HIMEKJLC_01701 4.4e-32 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HIMEKJLC_01702 3.5e-81 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_01703 1.3e-24 L transposase, IS605 OrfB family
HIMEKJLC_01704 2.8e-44 L Transposase IS200 like
HIMEKJLC_01705 9.7e-47 rmeB K transcriptional regulator, MerR family
HIMEKJLC_01706 1.4e-70 thiW S Thiamine-precursor transporter protein (ThiW)
HIMEKJLC_01707 4e-41 S ABC-type cobalt transport system, permease component
HIMEKJLC_01708 7.2e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HIMEKJLC_01709 2.9e-45 IQ reductase
HIMEKJLC_01710 2e-11 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMEKJLC_01716 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HIMEKJLC_01717 4.8e-266 lysP E amino acid
HIMEKJLC_01719 8.3e-156 I alpha/beta hydrolase fold
HIMEKJLC_01720 4.5e-115 lssY 3.6.1.27 I phosphatase
HIMEKJLC_01721 4.8e-82 S Threonine/Serine exporter, ThrE
HIMEKJLC_01722 6.3e-126 thrE S Putative threonine/serine exporter
HIMEKJLC_01723 1.3e-30 cspA K Cold shock protein
HIMEKJLC_01724 1.2e-123 sirR K iron dependent repressor
HIMEKJLC_01725 6e-163 czcD P cation diffusion facilitator family transporter
HIMEKJLC_01726 4.8e-112 S membrane
HIMEKJLC_01727 5.4e-108 S VIT family
HIMEKJLC_01728 8.5e-84 usp1 T Belongs to the universal stress protein A family
HIMEKJLC_01729 8.1e-33 elaA S GNAT family
HIMEKJLC_01730 2e-214 S CAAX protease self-immunity
HIMEKJLC_01731 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIMEKJLC_01732 6.4e-57
HIMEKJLC_01733 1.1e-72 merR K MerR HTH family regulatory protein
HIMEKJLC_01734 8.2e-231 lmrB EGP Major facilitator Superfamily
HIMEKJLC_01735 6.8e-114 S Domain of unknown function (DUF4811)
HIMEKJLC_01736 1.7e-90 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HIMEKJLC_01737 4.6e-168 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HIMEKJLC_01739 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIMEKJLC_01740 5.1e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HIMEKJLC_01741 9.1e-189 I Alpha beta
HIMEKJLC_01742 2.4e-225 L transposase, IS605 OrfB family
HIMEKJLC_01743 1.6e-42 L Transposase IS200 like
HIMEKJLC_01744 3e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
HIMEKJLC_01745 4.3e-250 yjjP S Putative threonine/serine exporter
HIMEKJLC_01746 3.8e-162 mleR K LysR family transcriptional regulator
HIMEKJLC_01747 6.1e-210 L Transposase
HIMEKJLC_01748 1.1e-10 L Transposase
HIMEKJLC_01749 2.1e-90 XK27_09620 S NADPH-dependent FMN reductase
HIMEKJLC_01750 6e-183 XK27_09615 S reductase
HIMEKJLC_01751 3.5e-129 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HIMEKJLC_01752 9.3e-31 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HIMEKJLC_01753 2.9e-81 tlpA2 L Transposase IS200 like
HIMEKJLC_01754 3.9e-27 L transposase, IS605 OrfB family
HIMEKJLC_01755 9.2e-172 L transposase, IS605 OrfB family
HIMEKJLC_01756 1.6e-20 nlhH_1 I acetylesterase activity
HIMEKJLC_01757 3.6e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIMEKJLC_01758 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HIMEKJLC_01759 4e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HIMEKJLC_01760 7.7e-293 scrB 3.2.1.26 GH32 G invertase
HIMEKJLC_01761 1.2e-258 S Uncharacterized protein conserved in bacteria (DUF2252)
HIMEKJLC_01762 2.7e-32 K LysR substrate binding domain
HIMEKJLC_01763 2.9e-100 K LysR substrate binding domain
HIMEKJLC_01764 2.3e-204 L transposase, IS605 OrfB family
HIMEKJLC_01765 3.4e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HIMEKJLC_01766 3.9e-110
HIMEKJLC_01768 8.2e-31 yjeM E Amino Acid
HIMEKJLC_01769 2.8e-168 ponA V Beta-lactamase enzyme family
HIMEKJLC_01770 5e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HIMEKJLC_01771 2e-97
HIMEKJLC_01772 1.3e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HIMEKJLC_01773 3e-107 lssY 3.6.1.27 I Acid phosphatase homologues
HIMEKJLC_01774 2.3e-53 S MazG-like family
HIMEKJLC_01775 0.0 L Helicase C-terminal domain protein
HIMEKJLC_01776 4.7e-70 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HIMEKJLC_01777 4.7e-94 K transcriptional regulator
HIMEKJLC_01778 1.1e-78 lmrB EGP Major facilitator Superfamily
HIMEKJLC_01779 2.2e-52 S Protein of unknown function (DUF917)
HIMEKJLC_01780 1.4e-113 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
HIMEKJLC_01782 1.4e-223 L Transposase
HIMEKJLC_01783 9.7e-18
HIMEKJLC_01786 1.1e-133 L PFAM transposase, IS4 family protein
HIMEKJLC_01787 1.8e-14 yfjR K Psort location Cytoplasmic, score
HIMEKJLC_01788 3.5e-38 S Cytochrome B5
HIMEKJLC_01789 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIMEKJLC_01790 4.1e-214 2.1.1.14 E methionine synthase, vitamin-B12 independent
HIMEKJLC_01791 2.1e-22 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HIMEKJLC_01792 1e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
HIMEKJLC_01793 1.9e-23 3.2.1.17 NU mannosyl-glycoprotein
HIMEKJLC_01794 8.4e-93 wecD K Acetyltransferase (GNAT) family
HIMEKJLC_01795 4e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HIMEKJLC_01796 1.7e-81 S Psort location Cytoplasmic, score
HIMEKJLC_01797 3.1e-69 K helix_turn_helix, mercury resistance
HIMEKJLC_01798 2.3e-133 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
HIMEKJLC_01799 3.5e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HIMEKJLC_01800 4.8e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HIMEKJLC_01801 9.9e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HIMEKJLC_01802 3.7e-134 ycsF S LamB/YcsF family
HIMEKJLC_01803 3.3e-209 ycsG P Natural resistance-associated macrophage protein
HIMEKJLC_01804 1.4e-204 EGP Major facilitator Superfamily
HIMEKJLC_01805 2.9e-81 tlpA2 L Transposase IS200 like
HIMEKJLC_01806 2.7e-238 L transposase, IS605 OrfB family
HIMEKJLC_01807 1.1e-253 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HIMEKJLC_01808 1.1e-52 trxA O Belongs to the thioredoxin family
HIMEKJLC_01809 1.2e-150 mleP3 S Membrane transport protein
HIMEKJLC_01811 6.7e-243 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIMEKJLC_01812 2.3e-241 yfnA E amino acid
HIMEKJLC_01813 1.6e-82 S NADPH-dependent FMN reductase
HIMEKJLC_01815 8.5e-156 L Thioesterase-like superfamily
HIMEKJLC_01816 6.4e-30 lacA S Hexapeptide repeat of succinyl-transferase
HIMEKJLC_01817 7.3e-261 argH 4.3.2.1 E argininosuccinate lyase
HIMEKJLC_01818 4e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HIMEKJLC_01819 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HIMEKJLC_01820 1.4e-30 K Transcriptional regulator
HIMEKJLC_01821 1.5e-16 1.3.1.9 S Nitronate monooxygenase
HIMEKJLC_01822 2.3e-53 K Helix-turn-helix domain
HIMEKJLC_01823 1.2e-105 S Domain of unknown function (DUF4767)
HIMEKJLC_01824 1.5e-07
HIMEKJLC_01825 7.1e-239 L transposase, IS605 OrfB family
HIMEKJLC_01826 2.8e-07 tlpA2 L Transposase IS200 like
HIMEKJLC_01827 3.4e-222 L Transposase
HIMEKJLC_01828 4.7e-102 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HIMEKJLC_01829 8.4e-100 pnuC H nicotinamide mononucleotide transporter
HIMEKJLC_01830 1.4e-21 2.7.6.5 T Region found in RelA / SpoT proteins
HIMEKJLC_01831 1.1e-268 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HIMEKJLC_01832 1.8e-141 L PFAM Integrase catalytic region
HIMEKJLC_01833 2.4e-104 IQ reductase
HIMEKJLC_01834 1.1e-80 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIMEKJLC_01835 6.6e-119 metQ_4 P Belongs to the nlpA lipoprotein family
HIMEKJLC_01836 2e-94 metI P ABC transporter permease
HIMEKJLC_01837 5.9e-133 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIMEKJLC_01838 4e-49 yebR 1.8.4.14 T GAF domain
HIMEKJLC_01839 8.4e-145 tra L Transposase and inactivated derivatives, IS30 family
HIMEKJLC_01840 1.6e-36 K DNA-binding response regulator
HIMEKJLC_01841 6.1e-235 L transposase, IS605 OrfB family
HIMEKJLC_01842 3e-09 sptS 2.7.13.3 T Histidine kinase
HIMEKJLC_01843 9.3e-95 sptS 2.7.13.3 T Histidine kinase
HIMEKJLC_01844 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
HIMEKJLC_01845 8e-102 2.3.1.128 K acetyltransferase
HIMEKJLC_01846 1e-102 IQ Dehydrogenase reductase
HIMEKJLC_01847 2.2e-17 IQ Dehydrogenase reductase
HIMEKJLC_01848 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIMEKJLC_01849 2.8e-160 EG EamA-like transporter family
HIMEKJLC_01850 0.0 helD 3.6.4.12 L DNA helicase
HIMEKJLC_01851 4.3e-118 dedA S SNARE associated Golgi protein
HIMEKJLC_01852 2e-120 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HIMEKJLC_01853 1.2e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIMEKJLC_01854 2.7e-238 L transposase, IS605 OrfB family
HIMEKJLC_01855 6.5e-19 tlpA2 L Transposase IS200 like
HIMEKJLC_01856 3.2e-109 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HIMEKJLC_01857 5.7e-80 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HIMEKJLC_01858 2e-55 pnuC H nicotinamide mononucleotide transporter
HIMEKJLC_01859 3.7e-65 pnuC H nicotinamide mononucleotide transporter
HIMEKJLC_01860 1.6e-296 ybeC E amino acid
HIMEKJLC_01861 2e-80 K FR47-like protein
HIMEKJLC_01862 1.4e-223 L Transposase
HIMEKJLC_01863 1.9e-46 V domain protein
HIMEKJLC_01864 2.5e-147 V domain protein
HIMEKJLC_01865 3.3e-92 K Transcriptional regulator (TetR family)
HIMEKJLC_01866 9e-187 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HIMEKJLC_01867 4.4e-169
HIMEKJLC_01869 4e-83 zur P Belongs to the Fur family
HIMEKJLC_01870 2.8e-105 gmk2 2.7.4.8 F Guanylate kinase
HIMEKJLC_01871 2.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HIMEKJLC_01872 2.6e-205 yfnA E Amino Acid
HIMEKJLC_01873 1.4e-239 L transposase, IS605 OrfB family
HIMEKJLC_01874 2.9e-81 tlpA2 L Transposase IS200 like
HIMEKJLC_01875 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HIMEKJLC_01876 3.1e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
HIMEKJLC_01877 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HIMEKJLC_01878 2.1e-273 S Uncharacterized protein conserved in bacteria (DUF2325)
HIMEKJLC_01879 2.5e-180 1.17.4.1 F Ribonucleotide reductase, small chain
HIMEKJLC_01880 3.7e-168 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
HIMEKJLC_01881 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIMEKJLC_01882 1.4e-83 nrdI F NrdI Flavodoxin like
HIMEKJLC_01883 5.1e-110 M ErfK YbiS YcfS YnhG
HIMEKJLC_01885 3.4e-205 nrnB S DHHA1 domain
HIMEKJLC_01886 1.3e-27 S ABC transporter, ATP-binding protein
HIMEKJLC_01887 1.5e-245 S ABC transporter, ATP-binding protein
HIMEKJLC_01888 1.9e-178 ABC-SBP S ABC transporter
HIMEKJLC_01889 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HIMEKJLC_01890 1e-131 XK27_08845 S ABC transporter, ATP-binding protein
HIMEKJLC_01891 2.8e-224 amtB P ammonium transporter
HIMEKJLC_01892 6.1e-233 mepA V MATE efflux family protein
HIMEKJLC_01893 5.8e-171 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HIMEKJLC_01894 7.4e-258 pgi 5.3.1.9 G Belongs to the GPI family
HIMEKJLC_01895 8.8e-184 fruR3 K Transcriptional regulator, LacI family
HIMEKJLC_01896 1.1e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HIMEKJLC_01897 7.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIMEKJLC_01898 9.4e-152 L transposase, IS605 OrfB family
HIMEKJLC_01899 2.4e-62 L transposase, IS605 OrfB family
HIMEKJLC_01900 2.8e-44 L Transposase IS200 like
HIMEKJLC_01901 1.8e-116 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HIMEKJLC_01902 1e-56 trxA1 O Belongs to the thioredoxin family
HIMEKJLC_01903 1.4e-139 terC P membrane
HIMEKJLC_01904 3e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIMEKJLC_01905 1.1e-169 corA P CorA-like Mg2+ transporter protein
HIMEKJLC_01906 4.9e-243 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_01907 8.7e-227 pbuX F xanthine permease
HIMEKJLC_01908 1.6e-104 L PFAM Integrase catalytic region
HIMEKJLC_01909 1.4e-29 L Helix-turn-helix domain
HIMEKJLC_01910 3.2e-133 qorB 1.6.5.2 GM NmrA-like family
HIMEKJLC_01911 2.7e-125 pgm3 G phosphoglycerate mutase family
HIMEKJLC_01912 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIMEKJLC_01913 7.7e-85
HIMEKJLC_01914 3.7e-106 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HIMEKJLC_01915 1.2e-100 dps P Belongs to the Dps family
HIMEKJLC_01916 2.8e-32 copZ P Heavy-metal-associated domain
HIMEKJLC_01917 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HIMEKJLC_01918 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HIMEKJLC_01919 2e-180 iunH2 3.2.2.1 F nucleoside hydrolase
HIMEKJLC_01920 5.9e-100 S ABC-type cobalt transport system, permease component
HIMEKJLC_01921 1.7e-254 cbiO1 S ABC transporter, ATP-binding protein
HIMEKJLC_01922 1.2e-112 P Cobalt transport protein
HIMEKJLC_01923 2e-10 yvlA
HIMEKJLC_01924 0.0 yjcE P Sodium proton antiporter
HIMEKJLC_01925 1.4e-245 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_01926 1e-57 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HIMEKJLC_01927 3.3e-106 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HIMEKJLC_01928 1.6e-73 O OsmC-like protein
HIMEKJLC_01929 1.3e-184 D Alpha beta
HIMEKJLC_01930 8.4e-75 K Transcriptional regulator
HIMEKJLC_01931 5.5e-158
HIMEKJLC_01932 1.6e-18
HIMEKJLC_01933 2.3e-58
HIMEKJLC_01934 3.1e-75 uspA T universal stress protein
HIMEKJLC_01936 9.7e-130 qmcA O prohibitin homologues
HIMEKJLC_01937 1.6e-244 glpT G Major Facilitator Superfamily
HIMEKJLC_01938 1.2e-222 L Transposase
HIMEKJLC_01939 2.2e-132 L PFAM transposase, IS4 family protein
HIMEKJLC_01940 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIMEKJLC_01941 1.7e-21 fucP G Major Facilitator Superfamily
HIMEKJLC_01942 5.7e-172 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIMEKJLC_01943 8.3e-260 G PTS system Galactitol-specific IIC component
HIMEKJLC_01944 5.6e-186 K helix_turn _helix lactose operon repressor
HIMEKJLC_01945 1.2e-277 yjeM E Amino Acid
HIMEKJLC_01947 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HIMEKJLC_01948 8.5e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HIMEKJLC_01949 2.7e-129 gntR K UbiC transcription regulator-associated domain protein
HIMEKJLC_01950 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIMEKJLC_01951 7.2e-130
HIMEKJLC_01952 1.3e-265 pipD E Dipeptidase
HIMEKJLC_01953 2.2e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HIMEKJLC_01954 2.5e-39 M1-874 K Domain of unknown function (DUF1836)
HIMEKJLC_01955 5.2e-90 GM epimerase
HIMEKJLC_01956 3.6e-252 yhdP S Transporter associated domain
HIMEKJLC_01957 2.7e-82 nrdI F Belongs to the NrdI family
HIMEKJLC_01958 6.5e-75 S 3-demethylubiquinone-9 3-methyltransferase
HIMEKJLC_01959 1.1e-206 yeaN P Transporter, major facilitator family protein
HIMEKJLC_01960 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIMEKJLC_01961 2.3e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIMEKJLC_01962 1.8e-81 uspA T universal stress protein
HIMEKJLC_01963 5e-139 L Transposase
HIMEKJLC_01964 4e-50 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMEKJLC_01965 4.4e-65 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMEKJLC_01966 6.8e-176 K helix_turn _helix lactose operon repressor
HIMEKJLC_01967 0.0 pepF E oligoendopeptidase F
HIMEKJLC_01968 1.2e-233 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIMEKJLC_01969 2.7e-25 S Membrane
HIMEKJLC_01970 1.1e-47 S Membrane
HIMEKJLC_01971 5.1e-22 S Membrane
HIMEKJLC_01972 2.1e-274 lacS G Transporter
HIMEKJLC_01973 0.0 rafA 3.2.1.22 G alpha-galactosidase
HIMEKJLC_01974 1.9e-178 galR K Transcriptional regulator
HIMEKJLC_01975 1.4e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HIMEKJLC_01976 1.8e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HIMEKJLC_01977 7.9e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HIMEKJLC_01978 1.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
HIMEKJLC_01979 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
HIMEKJLC_01980 6.9e-36
HIMEKJLC_01981 8.7e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HIMEKJLC_01982 1.1e-119 tcyB U Binding-protein-dependent transport system inner membrane component
HIMEKJLC_01983 5.7e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HIMEKJLC_01984 2e-52
HIMEKJLC_01985 2.9e-168 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMEKJLC_01986 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIMEKJLC_01987 2.9e-145 pnuC H nicotinamide mononucleotide transporter
HIMEKJLC_01988 7.7e-91 ymdB S Macro domain protein
HIMEKJLC_01989 0.0 pepO 3.4.24.71 O Peptidase family M13
HIMEKJLC_01990 2e-228 pbuG S permease
HIMEKJLC_01991 4.7e-45
HIMEKJLC_01992 5.8e-214 S Putative metallopeptidase domain
HIMEKJLC_01993 1.9e-206 3.1.3.1 S associated with various cellular activities
HIMEKJLC_01994 1.3e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HIMEKJLC_01995 1.5e-64 yeaO S Protein of unknown function, DUF488
HIMEKJLC_01997 4.8e-125 yrkL S Flavodoxin-like fold
HIMEKJLC_01998 1.5e-55
HIMEKJLC_01999 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HIMEKJLC_02000 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIMEKJLC_02001 1.9e-102
HIMEKJLC_02002 9.5e-26
HIMEKJLC_02003 8.3e-76 scrR K Transcriptional regulator, LacI family
HIMEKJLC_02004 1.3e-82 scrR K Transcriptional regulator, LacI family
HIMEKJLC_02005 1.5e-172 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIMEKJLC_02006 6.5e-182 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_02007 1.7e-45 czrA K Transcriptional regulator, ArsR family
HIMEKJLC_02008 1.2e-74 argR K Regulates arginine biosynthesis genes
HIMEKJLC_02009 2.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HIMEKJLC_02010 4.7e-156 hrtB V ABC transporter permease
HIMEKJLC_02011 1.1e-107 ygfC K Bacterial regulatory proteins, tetR family
HIMEKJLC_02012 1.1e-53 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HIMEKJLC_02013 1.1e-194 L transposase, IS605 OrfB family
HIMEKJLC_02014 4.7e-224 L Transposase
HIMEKJLC_02015 1.2e-32 L transposase, IS605 OrfB family
HIMEKJLC_02016 7.5e-244 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMEKJLC_02017 3.2e-252 mntH P H( )-stimulated, divalent metal cation uptake system
HIMEKJLC_02018 1.5e-21
HIMEKJLC_02019 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIMEKJLC_02020 2.9e-68 L nuclease
HIMEKJLC_02021 6e-160 F DNA/RNA non-specific endonuclease
HIMEKJLC_02022 1.1e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HIMEKJLC_02023 5.5e-289 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIMEKJLC_02024 1.9e-289 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIMEKJLC_02025 0.0 asnB 6.3.5.4 E Asparagine synthase
HIMEKJLC_02026 3.6e-218 lysP E amino acid
HIMEKJLC_02027 2.1e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HIMEKJLC_02028 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HIMEKJLC_02029 5.6e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HIMEKJLC_02030 2.4e-145 jag S R3H domain protein
HIMEKJLC_02031 7.5e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIMEKJLC_02032 9.3e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HIMEKJLC_02033 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HIMEKJLC_02035 5.4e-43 K Cro/C1-type HTH DNA-binding domain
HIMEKJLC_02036 6.1e-25 L Helix-turn-helix domain
HIMEKJLC_02037 4.1e-182 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HIMEKJLC_02038 7.7e-122 IQ reductase
HIMEKJLC_02039 1.1e-12 S Homeodomain-like domain
HIMEKJLC_02041 2.4e-99 D Cellulose biosynthesis protein BcsQ
HIMEKJLC_02042 7.9e-97 xerC L Phage integrase, N-terminal SAM-like domain
HIMEKJLC_02043 3.1e-09
HIMEKJLC_02044 3.6e-123 copB 3.6.3.4 P P-type ATPase
HIMEKJLC_02045 4.7e-115 copB 3.6.3.4 P P-type ATPase
HIMEKJLC_02046 2e-16 copB 3.6.3.4 P P-type ATPase
HIMEKJLC_02048 1.1e-74 K Copper transport repressor CopY TcrY
HIMEKJLC_02049 1.4e-56 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HIMEKJLC_02050 1.1e-64 S Initiator Replication protein
HIMEKJLC_02051 2e-66 tcmJ G COG0662 Mannose-6-phosphate isomerase
HIMEKJLC_02054 5.4e-43 K Cro/C1-type HTH DNA-binding domain
HIMEKJLC_02055 6.9e-25 L Helix-turn-helix domain
HIMEKJLC_02056 2e-65
HIMEKJLC_02057 2.6e-102 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HIMEKJLC_02058 7.7e-122 IQ reductase
HIMEKJLC_02059 1.1e-12 S Homeodomain-like domain
HIMEKJLC_02061 2.4e-99 D Cellulose biosynthesis protein BcsQ
HIMEKJLC_02062 1.4e-67 xerC L Phage integrase, N-terminal SAM-like domain
HIMEKJLC_02064 0.0 copB 3.6.3.4 P P-type ATPase
HIMEKJLC_02065 1.1e-74 K Copper transport repressor CopY TcrY
HIMEKJLC_02066 1.4e-56 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HIMEKJLC_02067 3.3e-37 mdt(A) EGP Major facilitator Superfamily
HIMEKJLC_02068 1.1e-64 S Initiator Replication protein
HIMEKJLC_02069 2e-66 tcmJ G COG0662 Mannose-6-phosphate isomerase
HIMEKJLC_02072 5.4e-43 K Cro/C1-type HTH DNA-binding domain
HIMEKJLC_02073 6.1e-25 L Helix-turn-helix domain
HIMEKJLC_02074 4.1e-182 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HIMEKJLC_02075 7.7e-122 IQ reductase
HIMEKJLC_02076 1.1e-12 S Homeodomain-like domain
HIMEKJLC_02078 2.4e-99 D Cellulose biosynthesis protein BcsQ
HIMEKJLC_02079 7.9e-97 xerC L Phage integrase, N-terminal SAM-like domain
HIMEKJLC_02081 0.0 copB 3.6.3.4 P P-type ATPase
HIMEKJLC_02082 1.1e-74 K Copper transport repressor CopY TcrY
HIMEKJLC_02083 1.4e-56 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HIMEKJLC_02084 3.3e-37 mdt(A) EGP Major facilitator Superfamily
HIMEKJLC_02085 2.4e-64 S Initiator Replication protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)