ORF_ID e_value Gene_name EC_number CAZy COGs Description
ICNLOFLE_00001 2.3e-228 L Transposase DDE domain
ICNLOFLE_00002 1.6e-154 mod 2.1.1.72 L DNA methylase
ICNLOFLE_00003 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
ICNLOFLE_00004 2.5e-217 yttB EGP Major facilitator Superfamily
ICNLOFLE_00005 3.3e-144 cof S Sucrose-6F-phosphate phosphohydrolase
ICNLOFLE_00006 1.5e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
ICNLOFLE_00007 0.0 pepO 3.4.24.71 O Peptidase family M13
ICNLOFLE_00008 4.5e-74 K Acetyltransferase (GNAT) domain
ICNLOFLE_00009 6.2e-165 degV S Uncharacterised protein, DegV family COG1307
ICNLOFLE_00010 5e-120 qmcA O prohibitin homologues
ICNLOFLE_00011 3.2e-29
ICNLOFLE_00012 1.8e-133 lys M Glycosyl hydrolases family 25
ICNLOFLE_00013 1.1e-59 S Protein of unknown function (DUF1093)
ICNLOFLE_00014 2e-61 S Domain of unknown function (DUF4828)
ICNLOFLE_00015 7e-178 mocA S Oxidoreductase
ICNLOFLE_00016 4.5e-236 yfmL 3.6.4.13 L DEAD DEAH box helicase
ICNLOFLE_00017 6.8e-48 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
ICNLOFLE_00018 4.8e-70 S Domain of unknown function (DUF3284)
ICNLOFLE_00020 3.4e-07
ICNLOFLE_00021 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
ICNLOFLE_00022 1.3e-237 pepS E Thermophilic metalloprotease (M29)
ICNLOFLE_00023 2.7e-111 K Bacterial regulatory proteins, tetR family
ICNLOFLE_00024 4e-259 S Uncharacterized protein conserved in bacteria (DUF2252)
ICNLOFLE_00025 9.6e-178 yihY S Belongs to the UPF0761 family
ICNLOFLE_00026 1.9e-80 fld C Flavodoxin
ICNLOFLE_00027 2.2e-159 map 3.4.11.18 E Methionine Aminopeptidase
ICNLOFLE_00028 1.1e-197 M Glycosyltransferase like family 2
ICNLOFLE_00030 4.5e-29
ICNLOFLE_00031 6.2e-199 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
ICNLOFLE_00032 4.7e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ICNLOFLE_00033 1.4e-97 N domain, Protein
ICNLOFLE_00034 4.1e-294 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ICNLOFLE_00035 3.3e-309 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ICNLOFLE_00036 0.0 S Bacterial membrane protein YfhO
ICNLOFLE_00037 9.6e-303 S Psort location CytoplasmicMembrane, score
ICNLOFLE_00038 1.6e-83 S Fic/DOC family
ICNLOFLE_00039 4.3e-172 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
ICNLOFLE_00040 2.1e-109
ICNLOFLE_00041 8.6e-168 yqjA S Putative aromatic acid exporter C-terminal domain
ICNLOFLE_00042 2.1e-31 cspC K Cold shock protein
ICNLOFLE_00043 9.8e-28 chpR T PFAM SpoVT AbrB
ICNLOFLE_00044 8.1e-82 yvbK 3.1.3.25 K GNAT family
ICNLOFLE_00045 1.6e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
ICNLOFLE_00046 1.2e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ICNLOFLE_00047 9.6e-242 pbuX F xanthine permease
ICNLOFLE_00048 1.1e-203 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ICNLOFLE_00049 2.4e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ICNLOFLE_00051 1.2e-103
ICNLOFLE_00052 3.6e-129
ICNLOFLE_00053 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ICNLOFLE_00055 2.6e-109 vanZ V VanZ like family
ICNLOFLE_00056 1e-151 glcU U sugar transport
ICNLOFLE_00057 4.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
ICNLOFLE_00059 2.9e-47 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
ICNLOFLE_00060 2.3e-116 F DNA/RNA non-specific endonuclease
ICNLOFLE_00061 4.1e-77 yttA 2.7.13.3 S Pfam Transposase IS66
ICNLOFLE_00062 3e-231 wbbX GT2,GT4 M Glycosyl transferases group 1
ICNLOFLE_00063 3.8e-173 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
ICNLOFLE_00064 1e-81 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
ICNLOFLE_00066 1.2e-17
ICNLOFLE_00067 3.3e-193 yttB EGP Major facilitator Superfamily
ICNLOFLE_00068 7.5e-285 pipD E Dipeptidase
ICNLOFLE_00070 8.7e-09
ICNLOFLE_00071 1.5e-132 G Phosphoglycerate mutase family
ICNLOFLE_00072 1.1e-121 K Bacterial regulatory proteins, tetR family
ICNLOFLE_00073 0.0 ycfI V ABC transporter, ATP-binding protein
ICNLOFLE_00074 0.0 yfiC V ABC transporter
ICNLOFLE_00075 6.6e-139 S NADPH-dependent FMN reductase
ICNLOFLE_00076 2.3e-164 1.13.11.2 S glyoxalase
ICNLOFLE_00077 3.1e-192 ampC V Beta-lactamase
ICNLOFLE_00078 6.5e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
ICNLOFLE_00079 2.7e-111 tdk 2.7.1.21 F thymidine kinase
ICNLOFLE_00080 5.1e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICNLOFLE_00081 1.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ICNLOFLE_00082 4.1e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ICNLOFLE_00083 2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICNLOFLE_00084 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICNLOFLE_00085 3.9e-125 atpB C it plays a direct role in the translocation of protons across the membrane
ICNLOFLE_00086 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICNLOFLE_00087 1.5e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICNLOFLE_00088 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICNLOFLE_00089 6.1e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICNLOFLE_00090 2.1e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICNLOFLE_00091 3.3e-10
ICNLOFLE_00092 2.3e-249 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICNLOFLE_00093 1.6e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ICNLOFLE_00094 6.4e-32 ywzB S Protein of unknown function (DUF1146)
ICNLOFLE_00095 4.5e-180 mbl D Cell shape determining protein MreB Mrl
ICNLOFLE_00096 1.4e-25 epuA S DNA-directed RNA polymerase subunit beta
ICNLOFLE_00097 2.4e-55 yidD S Could be involved in insertion of integral membrane proteins into the membrane
ICNLOFLE_00098 1.3e-31 S Protein of unknown function (DUF2969)
ICNLOFLE_00099 5.8e-222 rodA D Belongs to the SEDS family
ICNLOFLE_00100 3.6e-48 gcvH E glycine cleavage
ICNLOFLE_00101 1.4e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ICNLOFLE_00102 8.5e-148 P Belongs to the nlpA lipoprotein family
ICNLOFLE_00103 7.7e-149 P Belongs to the nlpA lipoprotein family
ICNLOFLE_00104 2.4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICNLOFLE_00105 8.8e-106 metI P ABC transporter permease
ICNLOFLE_00106 1.9e-141 sufC O FeS assembly ATPase SufC
ICNLOFLE_00107 4.1e-192 sufD O FeS assembly protein SufD
ICNLOFLE_00108 1.2e-227 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICNLOFLE_00109 2.9e-78 nifU C SUF system FeS assembly protein, NifU family
ICNLOFLE_00110 5.6e-280 sufB O assembly protein SufB
ICNLOFLE_00111 1.8e-26
ICNLOFLE_00112 4.9e-66 yueI S Protein of unknown function (DUF1694)
ICNLOFLE_00113 5.8e-180 S Protein of unknown function (DUF2785)
ICNLOFLE_00114 9.7e-158 2.3.1.19 K Helix-turn-helix XRE-family like proteins
ICNLOFLE_00115 1.5e-83 usp6 T universal stress protein
ICNLOFLE_00116 1.7e-39
ICNLOFLE_00118 6e-239 rarA L recombination factor protein RarA
ICNLOFLE_00119 0.0 6.3.2.2, 6.3.2.4 M Mur ligase middle domain protein
ICNLOFLE_00120 4.6e-73 yueI S Protein of unknown function (DUF1694)
ICNLOFLE_00121 1.2e-106 yktB S Belongs to the UPF0637 family
ICNLOFLE_00122 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
ICNLOFLE_00123 7.3e-150 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
ICNLOFLE_00124 2.6e-121 G Phosphoglycerate mutase family
ICNLOFLE_00125 2.8e-154 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICNLOFLE_00126 1.1e-164 IQ NAD dependent epimerase/dehydratase family
ICNLOFLE_00127 3.5e-137 pnuC H nicotinamide mononucleotide transporter
ICNLOFLE_00128 8.9e-133 dck 2.7.1.74 F deoxynucleoside kinase
ICNLOFLE_00129 2.6e-157 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
ICNLOFLE_00130 0.0 oppA E ABC transporter, substratebinding protein
ICNLOFLE_00131 7.6e-150 T GHKL domain
ICNLOFLE_00132 1.2e-120 T Transcriptional regulatory protein, C terminal
ICNLOFLE_00133 4.1e-167 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
ICNLOFLE_00134 1.4e-128 S ABC-2 family transporter protein
ICNLOFLE_00135 1.6e-160 K Transcriptional regulator
ICNLOFLE_00136 3.6e-78 yphH S Cupin domain
ICNLOFLE_00137 2.1e-54 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
ICNLOFLE_00138 7.9e-36
ICNLOFLE_00139 6.1e-37 K Psort location Cytoplasmic, score
ICNLOFLE_00140 3.9e-25 K Psort location Cytoplasmic, score
ICNLOFLE_00141 1.6e-97 1.6.5.5 C Zinc-binding dehydrogenase
ICNLOFLE_00142 1.9e-88 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICNLOFLE_00143 3.3e-158 2.3.1.128 K Acetyltransferase (GNAT) domain
ICNLOFLE_00144 2.2e-84 K Acetyltransferase (GNAT) domain
ICNLOFLE_00145 2.8e-154 S Uncharacterised protein, DegV family COG1307
ICNLOFLE_00146 1.1e-115
ICNLOFLE_00147 1.1e-102 desR K helix_turn_helix, Lux Regulon
ICNLOFLE_00148 6.4e-199 desK 2.7.13.3 T Histidine kinase
ICNLOFLE_00149 8.2e-129 yvfS V ABC-2 type transporter
ICNLOFLE_00150 6.3e-157 yvfR V ABC transporter
ICNLOFLE_00151 2.5e-275
ICNLOFLE_00152 1.6e-180
ICNLOFLE_00153 2.6e-46 D Putative exonuclease SbcCD, C subunit
ICNLOFLE_00154 0.0 D Putative exonuclease SbcCD, C subunit
ICNLOFLE_00155 4.9e-132 S Protein of unknown function C-terminus (DUF2399)
ICNLOFLE_00156 7.5e-83 K Acetyltransferase (GNAT) domain
ICNLOFLE_00157 0.0 yhgF K Tex-like protein N-terminal domain protein
ICNLOFLE_00158 1.1e-80
ICNLOFLE_00159 1.1e-138 puuD S peptidase C26
ICNLOFLE_00160 1e-227 steT E Amino acid permease
ICNLOFLE_00161 1.1e-92 K Cro/C1-type HTH DNA-binding domain
ICNLOFLE_00162 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICNLOFLE_00163 1.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
ICNLOFLE_00164 7.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ICNLOFLE_00165 3.2e-217 iscS2 2.8.1.7 E Aminotransferase class V
ICNLOFLE_00166 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICNLOFLE_00167 1.2e-115 rex K CoA binding domain
ICNLOFLE_00168 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ICNLOFLE_00169 3.9e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ICNLOFLE_00170 1.9e-115 S Haloacid dehalogenase-like hydrolase
ICNLOFLE_00171 4.3e-118 radC L DNA repair protein
ICNLOFLE_00172 7.8e-180 mreB D cell shape determining protein MreB
ICNLOFLE_00173 8.5e-151 mreC M Involved in formation and maintenance of cell shape
ICNLOFLE_00174 4.7e-83 mreD M rod shape-determining protein MreD
ICNLOFLE_00175 2e-112 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
ICNLOFLE_00176 1.1e-141 minD D Belongs to the ParA family
ICNLOFLE_00177 4.7e-109 artQ P ABC transporter permease
ICNLOFLE_00178 6.4e-111 glnQ 3.6.3.21 E ABC transporter
ICNLOFLE_00179 9.5e-152 aatB ET ABC transporter substrate-binding protein
ICNLOFLE_00180 1.7e-12
ICNLOFLE_00181 1.6e-11
ICNLOFLE_00182 1.4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICNLOFLE_00183 8.6e-09 S Protein of unknown function (DUF4044)
ICNLOFLE_00184 1.2e-52
ICNLOFLE_00185 4.8e-78 mraZ K Belongs to the MraZ family
ICNLOFLE_00186 1.8e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ICNLOFLE_00187 6.2e-58 ftsL D cell division protein FtsL
ICNLOFLE_00188 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
ICNLOFLE_00189 9.2e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICNLOFLE_00190 6e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICNLOFLE_00191 5.3e-198 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICNLOFLE_00192 1.3e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ICNLOFLE_00193 3.6e-233 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ICNLOFLE_00194 3.1e-218 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICNLOFLE_00195 6.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ICNLOFLE_00196 5.2e-44 yggT D integral membrane protein
ICNLOFLE_00197 6.4e-145 ylmH S S4 domain protein
ICNLOFLE_00198 8.5e-81 divIVA D DivIVA protein
ICNLOFLE_00199 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICNLOFLE_00200 8.2e-37 cspA K Cold shock protein
ICNLOFLE_00201 1.5e-145 pstS P Phosphate
ICNLOFLE_00202 8.1e-263 ydiC1 EGP Major facilitator Superfamily
ICNLOFLE_00203 6.2e-208 yaaN P Toxic anion resistance protein (TelA)
ICNLOFLE_00204 6.9e-116 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
ICNLOFLE_00205 3.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
ICNLOFLE_00206 5.8e-34
ICNLOFLE_00207 2.4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ICNLOFLE_00208 4.9e-218 iscS 2.8.1.7 E Aminotransferase class V
ICNLOFLE_00209 1.3e-57 XK27_04120 S Putative amino acid metabolism
ICNLOFLE_00210 0.0 uvrA2 L ABC transporter
ICNLOFLE_00211 7.4e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ICNLOFLE_00212 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
ICNLOFLE_00213 1.4e-116 S Repeat protein
ICNLOFLE_00214 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ICNLOFLE_00215 2.1e-243 els S Sterol carrier protein domain
ICNLOFLE_00216 6.5e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
ICNLOFLE_00217 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICNLOFLE_00218 4.9e-31 ykzG S Belongs to the UPF0356 family
ICNLOFLE_00220 1.4e-72
ICNLOFLE_00221 3.9e-26
ICNLOFLE_00222 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ICNLOFLE_00223 6.2e-135 S E1-E2 ATPase
ICNLOFLE_00224 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
ICNLOFLE_00225 4.8e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
ICNLOFLE_00226 1.4e-242 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICNLOFLE_00227 1.5e-258 lpdA 1.8.1.4 C Dehydrogenase
ICNLOFLE_00228 5.4e-156 1.1.1.27 C L-malate dehydrogenase activity
ICNLOFLE_00229 1.4e-46 yktA S Belongs to the UPF0223 family
ICNLOFLE_00230 5e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
ICNLOFLE_00231 0.0 typA T GTP-binding protein TypA
ICNLOFLE_00232 4.2e-209 ftsW D Belongs to the SEDS family
ICNLOFLE_00233 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ICNLOFLE_00234 3.8e-57 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
ICNLOFLE_00235 1.6e-100 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
ICNLOFLE_00236 2.8e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ICNLOFLE_00237 2.1e-194 ylbL T Belongs to the peptidase S16 family
ICNLOFLE_00238 7.4e-118 comEA L Competence protein ComEA
ICNLOFLE_00239 0.0 comEC S Competence protein ComEC
ICNLOFLE_00240 2e-194 holA 2.7.7.7 L DNA polymerase III delta subunit
ICNLOFLE_00241 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
ICNLOFLE_00242 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICNLOFLE_00243 5.3e-127
ICNLOFLE_00244 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICNLOFLE_00245 1e-162 S Tetratricopeptide repeat
ICNLOFLE_00246 1.2e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICNLOFLE_00247 1.5e-83 M Protein of unknown function (DUF3737)
ICNLOFLE_00248 4e-133 cobB K Sir2 family
ICNLOFLE_00249 1.1e-62 pcaC 4.1.1.44 S Carboxymuconolactone decarboxylase family
ICNLOFLE_00250 7.9e-64 rmeD K helix_turn_helix, mercury resistance
ICNLOFLE_00251 2.6e-311 yknV V ABC transporter
ICNLOFLE_00252 3.6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ICNLOFLE_00253 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICNLOFLE_00254 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
ICNLOFLE_00255 1e-47 MA20_27270 S mazG nucleotide pyrophosphohydrolase
ICNLOFLE_00256 2.3e-20
ICNLOFLE_00257 6.5e-260 glnPH2 P ABC transporter permease
ICNLOFLE_00258 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICNLOFLE_00259 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ICNLOFLE_00260 1.3e-148 L PFAM Integrase catalytic region
ICNLOFLE_00261 6.9e-90 L Helix-turn-helix domain
ICNLOFLE_00262 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
ICNLOFLE_00263 1.5e-158 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
ICNLOFLE_00264 7.7e-132 fruR K DeoR C terminal sensor domain
ICNLOFLE_00265 2.1e-233 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICNLOFLE_00266 0.0 oatA I Acyltransferase
ICNLOFLE_00267 1.5e-183 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ICNLOFLE_00268 1.1e-121 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
ICNLOFLE_00269 1.3e-46 yrvD S Lipopolysaccharide assembly protein A domain
ICNLOFLE_00270 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ICNLOFLE_00271 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ICNLOFLE_00272 9.6e-95 M1-874 K Domain of unknown function (DUF1836)
ICNLOFLE_00273 1.4e-300 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
ICNLOFLE_00274 2.4e-145
ICNLOFLE_00275 1.3e-19 S Protein of unknown function (DUF2929)
ICNLOFLE_00276 0.0 dnaE 2.7.7.7 L DNA polymerase
ICNLOFLE_00277 3.5e-177 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
ICNLOFLE_00278 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
ICNLOFLE_00279 2.5e-72 yeaL S Protein of unknown function (DUF441)
ICNLOFLE_00280 6.9e-164 cvfB S S1 domain
ICNLOFLE_00281 3.3e-166 xerD D recombinase XerD
ICNLOFLE_00282 3.4e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICNLOFLE_00283 2.1e-126 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ICNLOFLE_00284 7.3e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICNLOFLE_00285 9.4e-138 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ICNLOFLE_00286 2.4e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ICNLOFLE_00287 1.4e-45 fer C 4Fe-4S single cluster domain of Ferredoxin I
ICNLOFLE_00288 9.7e-183 ypbB 5.1.3.1 S Helix-turn-helix domain
ICNLOFLE_00289 5e-265 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
ICNLOFLE_00290 2.7e-56 M Lysin motif
ICNLOFLE_00291 2.6e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
ICNLOFLE_00292 1.1e-218 rpsA 1.17.7.4 J Ribosomal protein S1
ICNLOFLE_00293 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
ICNLOFLE_00294 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ICNLOFLE_00295 5.1e-237 S Tetratricopeptide repeat protein
ICNLOFLE_00296 4.8e-149 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ICNLOFLE_00297 3.6e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ICNLOFLE_00298 9.6e-85
ICNLOFLE_00299 0.0 yfmR S ABC transporter, ATP-binding protein
ICNLOFLE_00300 3.8e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICNLOFLE_00301 6.7e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ICNLOFLE_00302 9.6e-115 hly S protein, hemolysin III
ICNLOFLE_00303 2.3e-148 DegV S EDD domain protein, DegV family
ICNLOFLE_00304 7.8e-157 ypmR E GDSL-like Lipase/Acylhydrolase
ICNLOFLE_00305 9e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
ICNLOFLE_00306 1.5e-85 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICNLOFLE_00307 2.3e-40 yozE S Belongs to the UPF0346 family
ICNLOFLE_00308 1.1e-256 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
ICNLOFLE_00309 3e-56
ICNLOFLE_00311 8.9e-69 S Domain of unknown function (DUF4918)
ICNLOFLE_00312 1.3e-18 tnp2PF3 L Transposase DDE domain
ICNLOFLE_00313 1.6e-57 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICNLOFLE_00314 6.2e-44 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICNLOFLE_00315 5.4e-71 WQ51_03320 S Protein of unknown function (DUF1149)
ICNLOFLE_00316 2.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ICNLOFLE_00317 6.2e-154 rrmA 2.1.1.187 H Methyltransferase
ICNLOFLE_00318 2.8e-171 corA P CorA-like Mg2+ transporter protein
ICNLOFLE_00319 6.3e-190 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICNLOFLE_00320 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICNLOFLE_00321 4.2e-62 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
ICNLOFLE_00322 8.6e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
ICNLOFLE_00323 3.5e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
ICNLOFLE_00324 4.4e-112 cutC P Participates in the control of copper homeostasis
ICNLOFLE_00325 1.7e-201 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ICNLOFLE_00326 3.3e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
ICNLOFLE_00327 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICNLOFLE_00328 2.3e-122 yjbM 2.7.6.5 S RelA SpoT domain protein
ICNLOFLE_00329 2.7e-103 yjbK S CYTH
ICNLOFLE_00330 1.5e-115 yjbH Q Thioredoxin
ICNLOFLE_00331 5.5e-208 coiA 3.6.4.12 S Competence protein
ICNLOFLE_00332 6.7e-243 XK27_08635 S UPF0210 protein
ICNLOFLE_00333 1.5e-37 gcvR T Belongs to the UPF0237 family
ICNLOFLE_00334 7.6e-223 cpdA S Calcineurin-like phosphoesterase
ICNLOFLE_00335 1.3e-226 malY 4.4.1.8 E Aminotransferase, class I
ICNLOFLE_00336 5.8e-64 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
ICNLOFLE_00338 1.7e-95 FNV0100 F NUDIX domain
ICNLOFLE_00339 5e-140 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICNLOFLE_00340 2.1e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
ICNLOFLE_00341 6.9e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ICNLOFLE_00342 2.4e-279 ytgP S Polysaccharide biosynthesis protein
ICNLOFLE_00343 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICNLOFLE_00344 1e-119 3.6.1.27 I Acid phosphatase homologues
ICNLOFLE_00345 1.2e-113 S Domain of unknown function (DUF4811)
ICNLOFLE_00346 8.1e-266 lmrB EGP Major facilitator Superfamily
ICNLOFLE_00347 1.5e-80 merR K MerR HTH family regulatory protein
ICNLOFLE_00348 4.3e-275 emrY EGP Major facilitator Superfamily
ICNLOFLE_00349 1.3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICNLOFLE_00350 3.4e-99
ICNLOFLE_00352 1.2e-212 M Glycosyl hydrolases family 25
ICNLOFLE_00353 3e-67 S Pfam:Phage_holin_6_1
ICNLOFLE_00354 6.6e-39
ICNLOFLE_00356 7.6e-52
ICNLOFLE_00357 0.0 S cellulase activity
ICNLOFLE_00358 1.2e-237 S Phage tail protein
ICNLOFLE_00359 0.0 S peptidoglycan catabolic process
ICNLOFLE_00360 1.8e-21
ICNLOFLE_00361 4e-73 S Pfam:Phage_TTP_1
ICNLOFLE_00362 2.9e-29
ICNLOFLE_00363 5e-66 S exonuclease activity
ICNLOFLE_00364 1.2e-39 S Phage head-tail joining protein
ICNLOFLE_00365 3.6e-26 S Phage gp6-like head-tail connector protein
ICNLOFLE_00366 8e-22 S peptidase activity
ICNLOFLE_00367 4.9e-205 S peptidase activity
ICNLOFLE_00368 2.3e-105 S peptidase activity
ICNLOFLE_00369 1.6e-227 S Phage portal protein
ICNLOFLE_00371 0.0 S Phage Terminase
ICNLOFLE_00372 5.7e-77 S Phage terminase, small subunit
ICNLOFLE_00373 3.9e-73 S HNH endonuclease
ICNLOFLE_00376 1.9e-50
ICNLOFLE_00377 9.2e-55 S HNH endonuclease
ICNLOFLE_00378 8.9e-220 S GcrA cell cycle regulator
ICNLOFLE_00379 2.3e-156
ICNLOFLE_00380 6.5e-78
ICNLOFLE_00381 6.2e-38 S YopX protein
ICNLOFLE_00383 2.9e-21
ICNLOFLE_00385 1.8e-32 S Protein of unknown function (DUF1642)
ICNLOFLE_00386 3.7e-127 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
ICNLOFLE_00388 4.6e-56 S Protein of unknown function (DUF1064)
ICNLOFLE_00389 1.8e-67
ICNLOFLE_00392 1.1e-234 S DNA helicase activity
ICNLOFLE_00393 6.9e-113 S calcium ion binding
ICNLOFLE_00394 2.3e-59 S Single-strand binding protein family
ICNLOFLE_00395 1.2e-54 S HNH endonuclease
ICNLOFLE_00396 1.1e-121 S Pfam:HNHc_6
ICNLOFLE_00397 1.3e-41 S ERF superfamily
ICNLOFLE_00398 4.1e-81 S Siphovirus Gp157
ICNLOFLE_00403 4.3e-79 K Phage regulatory protein
ICNLOFLE_00404 3.6e-38 S sequence-specific DNA binding
ICNLOFLE_00405 4.2e-121 S sequence-specific DNA binding
ICNLOFLE_00406 2.1e-67 tcdC
ICNLOFLE_00407 3.9e-212 L Belongs to the 'phage' integrase family
ICNLOFLE_00408 4.5e-38 L PFAM Integrase catalytic region
ICNLOFLE_00409 1.2e-255 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
ICNLOFLE_00410 1.3e-113 S Bacteriocin-protection, YdeI or OmpD-Associated
ICNLOFLE_00411 2.1e-57 yjdF S Protein of unknown function (DUF2992)
ICNLOFLE_00414 4.4e-198 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
ICNLOFLE_00415 4.4e-223 maeN C 2-hydroxycarboxylate transporter family
ICNLOFLE_00416 3.2e-273 dcuS 2.7.13.3 T Single cache domain 3
ICNLOFLE_00417 9.6e-121 dpiA KT cheY-homologous receiver domain
ICNLOFLE_00418 1.7e-99
ICNLOFLE_00420 1.9e-150 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
ICNLOFLE_00421 1.4e-68
ICNLOFLE_00422 5.4e-132 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
ICNLOFLE_00423 6.8e-170 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ICNLOFLE_00425 8.8e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICNLOFLE_00426 1.5e-180 D Alpha beta
ICNLOFLE_00427 5.9e-185 lipA I Carboxylesterase family
ICNLOFLE_00428 1.2e-216 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
ICNLOFLE_00429 1e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICNLOFLE_00430 0.0 mtlR K Mga helix-turn-helix domain
ICNLOFLE_00431 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_00432 2.8e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ICNLOFLE_00433 4.3e-149 S haloacid dehalogenase-like hydrolase
ICNLOFLE_00434 2.8e-44
ICNLOFLE_00435 2e-14
ICNLOFLE_00436 2.4e-136
ICNLOFLE_00437 2.7e-224 spiA K IrrE N-terminal-like domain
ICNLOFLE_00438 9.6e-152 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICNLOFLE_00439 2e-126 V ABC transporter
ICNLOFLE_00440 4.7e-208 bacI V MacB-like periplasmic core domain
ICNLOFLE_00441 3.2e-183
ICNLOFLE_00442 0.0 M Leucine rich repeats (6 copies)
ICNLOFLE_00443 5.5e-225 mtnE 2.6.1.83 E Aminotransferase
ICNLOFLE_00444 3.7e-145 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
ICNLOFLE_00445 5.4e-150 M NLPA lipoprotein
ICNLOFLE_00448 6.2e-199 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
ICNLOFLE_00451 2.3e-226 amd 3.5.1.47 E Peptidase family M20/M25/M40
ICNLOFLE_00452 2.6e-80 S Threonine/Serine exporter, ThrE
ICNLOFLE_00453 1.9e-133 thrE S Putative threonine/serine exporter
ICNLOFLE_00455 1.3e-31
ICNLOFLE_00456 1e-274 V ABC transporter transmembrane region
ICNLOFLE_00458 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ICNLOFLE_00459 1.8e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ICNLOFLE_00460 1.3e-137 jag S R3H domain protein
ICNLOFLE_00461 6.4e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICNLOFLE_00462 1.9e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ICNLOFLE_00465 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
ICNLOFLE_00466 3.5e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICNLOFLE_00467 1.5e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ICNLOFLE_00468 6.4e-31 yaaA S S4 domain protein YaaA
ICNLOFLE_00469 4.8e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICNLOFLE_00470 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICNLOFLE_00471 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICNLOFLE_00472 4.7e-08 ssb_2 L Single-strand binding protein family
ICNLOFLE_00473 3e-15
ICNLOFLE_00475 2.1e-73 ssb_2 L Single-strand binding protein family
ICNLOFLE_00476 2.7e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
ICNLOFLE_00477 4.5e-58 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ICNLOFLE_00478 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICNLOFLE_00479 1.5e-91 yhbO 3.5.1.124 S DJ-1/PfpI family
ICNLOFLE_00480 3.4e-280 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
ICNLOFLE_00481 3.8e-182 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
ICNLOFLE_00482 2.1e-28
ICNLOFLE_00483 5.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICNLOFLE_00484 7.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ICNLOFLE_00485 4.4e-155 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ICNLOFLE_00486 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ICNLOFLE_00487 1.1e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ICNLOFLE_00488 1e-237 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ICNLOFLE_00489 3.3e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ICNLOFLE_00490 1.5e-236 pyrP F Permease
ICNLOFLE_00491 1.3e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ICNLOFLE_00493 1.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICNLOFLE_00494 9.2e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ICNLOFLE_00495 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
ICNLOFLE_00496 1.4e-63 S Family of unknown function (DUF5322)
ICNLOFLE_00497 7.2e-68 rnhA 3.1.26.4 L Ribonuclease HI
ICNLOFLE_00498 1.1e-107 XK27_02070 S Nitroreductase family
ICNLOFLE_00499 2.3e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICNLOFLE_00500 2e-55
ICNLOFLE_00501 7.4e-272 K Mga helix-turn-helix domain
ICNLOFLE_00502 4.5e-38 nrdH O Glutaredoxin
ICNLOFLE_00503 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICNLOFLE_00504 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICNLOFLE_00505 3.1e-164 K Transcriptional regulator
ICNLOFLE_00506 0.0 pepO 3.4.24.71 O Peptidase family M13
ICNLOFLE_00507 4.8e-193 lplA 6.3.1.20 H Lipoate-protein ligase
ICNLOFLE_00508 1.5e-33
ICNLOFLE_00509 7.8e-174 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
ICNLOFLE_00510 3.7e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
ICNLOFLE_00511 1.8e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ICNLOFLE_00512 6.2e-105 ypsA S Belongs to the UPF0398 family
ICNLOFLE_00513 3.3e-120 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ICNLOFLE_00514 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
ICNLOFLE_00515 2.3e-86 comEB 3.5.4.12 F ComE operon protein 2
ICNLOFLE_00516 9.7e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICNLOFLE_00517 1.1e-112 dnaD L DnaD domain protein
ICNLOFLE_00518 4.2e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
ICNLOFLE_00519 2.4e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
ICNLOFLE_00520 1.1e-86 ypmB S Protein conserved in bacteria
ICNLOFLE_00521 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
ICNLOFLE_00522 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
ICNLOFLE_00523 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
ICNLOFLE_00524 4.9e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
ICNLOFLE_00525 7.8e-180 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
ICNLOFLE_00526 9.5e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ICNLOFLE_00527 2.6e-263 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
ICNLOFLE_00528 3.2e-175
ICNLOFLE_00529 5.3e-141
ICNLOFLE_00530 9.7e-61 yitW S Iron-sulfur cluster assembly protein
ICNLOFLE_00531 1.9e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
ICNLOFLE_00532 6.7e-276 V (ABC) transporter
ICNLOFLE_00533 0.0 V ABC transporter transmembrane region
ICNLOFLE_00534 1.1e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ICNLOFLE_00535 4.5e-129 trmK 2.1.1.217 S SAM-dependent methyltransferase
ICNLOFLE_00536 4.4e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ICNLOFLE_00537 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ICNLOFLE_00538 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
ICNLOFLE_00539 1.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
ICNLOFLE_00540 1.3e-96 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
ICNLOFLE_00542 5.5e-127 V ATPases associated with a variety of cellular activities
ICNLOFLE_00543 6.2e-42 L Transposase DDE domain
ICNLOFLE_00544 6.2e-214 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICNLOFLE_00545 3e-303 frvR K Mga helix-turn-helix domain
ICNLOFLE_00546 6.3e-298 frvR K Mga helix-turn-helix domain
ICNLOFLE_00547 5e-268 lysP E amino acid
ICNLOFLE_00549 1.7e-128 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
ICNLOFLE_00550 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
ICNLOFLE_00551 1.6e-97
ICNLOFLE_00552 3.3e-100 2.3.1.128 J Acetyltransferase (GNAT) domain
ICNLOFLE_00553 2.7e-191 S Bacterial protein of unknown function (DUF916)
ICNLOFLE_00554 9.9e-103
ICNLOFLE_00555 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICNLOFLE_00556 4.1e-245 Z012_01130 S Fic/DOC family
ICNLOFLE_00557 1.1e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
ICNLOFLE_00558 4.4e-157 I alpha/beta hydrolase fold
ICNLOFLE_00559 3.9e-49
ICNLOFLE_00560 1.7e-69
ICNLOFLE_00561 1.7e-159 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
ICNLOFLE_00562 7.2e-124 citR K FCD
ICNLOFLE_00563 6.9e-267 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
ICNLOFLE_00564 5.2e-101 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ICNLOFLE_00565 1.3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
ICNLOFLE_00566 6.9e-156 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
ICNLOFLE_00567 2.2e-48 citD C Covalent carrier of the coenzyme of citrate lyase
ICNLOFLE_00568 2.6e-183 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ICNLOFLE_00570 1e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
ICNLOFLE_00571 1.8e-37 gcdC 2.3.1.12 I Biotin-requiring enzyme
ICNLOFLE_00572 5.8e-52
ICNLOFLE_00573 2.2e-241 citM C Citrate transporter
ICNLOFLE_00574 1.3e-41
ICNLOFLE_00575 1.8e-101 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
ICNLOFLE_00576 9.3e-89 K Acetyltransferase (GNAT) domain
ICNLOFLE_00577 9e-110 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
ICNLOFLE_00578 9.9e-58 K Transcriptional regulator PadR-like family
ICNLOFLE_00579 1.4e-90 ORF00048
ICNLOFLE_00580 3.3e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
ICNLOFLE_00581 4.4e-169 yjjC V ABC transporter
ICNLOFLE_00582 3.1e-287 M Exporter of polyketide antibiotics
ICNLOFLE_00583 7.3e-115 K Transcriptional regulator
ICNLOFLE_00584 2.4e-259 ypiB EGP Major facilitator Superfamily
ICNLOFLE_00585 6.7e-128 S membrane transporter protein
ICNLOFLE_00586 5.2e-187 K Helix-turn-helix domain
ICNLOFLE_00587 1.8e-164 S Alpha beta hydrolase
ICNLOFLE_00588 3.6e-61 yvoA_1 K Transcriptional regulator, GntR family
ICNLOFLE_00589 8.5e-128 skfE V ATPases associated with a variety of cellular activities
ICNLOFLE_00590 6.9e-21
ICNLOFLE_00591 3.1e-164 oppF P Oligopeptide/dipeptide transporter, C-terminal region
ICNLOFLE_00592 1.7e-201 oppD P Oligopeptide/dipeptide transporter, C-terminal region
ICNLOFLE_00593 4.4e-49
ICNLOFLE_00594 3e-173 amiD P N-terminal TM domain of oligopeptide transport permease C
ICNLOFLE_00595 1e-168 oppB P Binding-protein-dependent transport system inner membrane component
ICNLOFLE_00596 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
ICNLOFLE_00597 1.3e-38
ICNLOFLE_00598 1.1e-298 V ABC transporter transmembrane region
ICNLOFLE_00599 7e-292 V ABC transporter transmembrane region
ICNLOFLE_00600 6.5e-69 S Iron-sulphur cluster biosynthesis
ICNLOFLE_00601 0.0 XK27_08510 L Type III restriction protein res subunit
ICNLOFLE_00602 2.4e-161 2.7.1.39 S Phosphotransferase enzyme family
ICNLOFLE_00603 2.7e-116 zmp3 O Zinc-dependent metalloprotease
ICNLOFLE_00604 0.0 lytN 3.5.1.104 M LysM domain
ICNLOFLE_00606 3.2e-50 lciIC K Helix-turn-helix XRE-family like proteins
ICNLOFLE_00608 8e-304 L Reverse transcriptase (RNA-dependent DNA polymerase)
ICNLOFLE_00609 4.6e-56 L PFAM transposase, IS4 family protein
ICNLOFLE_00610 2.2e-114 L PFAM transposase, IS4 family protein
ICNLOFLE_00612 1.3e-38 repA S Replication initiator protein A
ICNLOFLE_00613 1.9e-58 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICNLOFLE_00614 1e-81 tnp2PF3 L Transposase DDE domain
ICNLOFLE_00615 2.8e-41 tnp2PF3 L Transposase DDE domain
ICNLOFLE_00616 7.4e-34
ICNLOFLE_00617 2.5e-32
ICNLOFLE_00618 5.4e-08
ICNLOFLE_00620 8.8e-09 yhjA S CsbD-like
ICNLOFLE_00621 4.8e-194 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
ICNLOFLE_00622 7.2e-46
ICNLOFLE_00623 5.3e-201 ltrA S Bacterial low temperature requirement A protein (LtrA)
ICNLOFLE_00624 1.9e-121 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICNLOFLE_00625 2e-92 ccpN K Domain in cystathionine beta-synthase and other proteins.
ICNLOFLE_00626 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
ICNLOFLE_00627 0.0 kup P Transport of potassium into the cell
ICNLOFLE_00628 1.9e-166 V ATPases associated with a variety of cellular activities
ICNLOFLE_00629 2.1e-211 S ABC-2 family transporter protein
ICNLOFLE_00630 4.5e-197
ICNLOFLE_00631 3.2e-261 pepC 3.4.22.40 E Peptidase C1-like family
ICNLOFLE_00632 8.8e-256 pepC 3.4.22.40 E aminopeptidase
ICNLOFLE_00633 4.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
ICNLOFLE_00634 1.9e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
ICNLOFLE_00635 8.5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ICNLOFLE_00636 1.8e-201 yacL S domain protein
ICNLOFLE_00637 4.9e-222 inlJ M MucBP domain
ICNLOFLE_00638 2.8e-61 K helix_turn_helix gluconate operon transcriptional repressor
ICNLOFLE_00639 7.7e-131 S Membrane
ICNLOFLE_00640 1.2e-141 yhfC S Putative membrane peptidase family (DUF2324)
ICNLOFLE_00641 3.3e-259 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICNLOFLE_00643 2.8e-105
ICNLOFLE_00644 4.3e-245 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
ICNLOFLE_00645 4.9e-162 K sequence-specific DNA binding
ICNLOFLE_00646 2.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICNLOFLE_00647 1.8e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ICNLOFLE_00648 1.2e-143 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICNLOFLE_00649 1.2e-97 yacP S YacP-like NYN domain
ICNLOFLE_00650 1.9e-192 XK27_00915 C Luciferase-like monooxygenase
ICNLOFLE_00651 5.1e-122 1.5.1.40 S Rossmann-like domain
ICNLOFLE_00652 9.6e-195
ICNLOFLE_00653 7.1e-223
ICNLOFLE_00654 8.1e-157 V ATPases associated with a variety of cellular activities
ICNLOFLE_00655 9.7e-158
ICNLOFLE_00656 1e-96
ICNLOFLE_00657 1.5e-149 T Calcineurin-like phosphoesterase superfamily domain
ICNLOFLE_00658 5e-79
ICNLOFLE_00659 2.9e-179 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICNLOFLE_00660 5.2e-99 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
ICNLOFLE_00661 1.7e-81 ynhH S NusG domain II
ICNLOFLE_00662 0.0 ndh 1.6.99.3 C NADH dehydrogenase
ICNLOFLE_00663 4.6e-139 cad S FMN_bind
ICNLOFLE_00664 5.3e-228 tnpB L Putative transposase DNA-binding domain
ICNLOFLE_00665 2.2e-196 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ICNLOFLE_00666 8.7e-165 menA 2.5.1.74 M UbiA prenyltransferase family
ICNLOFLE_00667 8.9e-173 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
ICNLOFLE_00668 8.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICNLOFLE_00669 1.5e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ICNLOFLE_00670 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
ICNLOFLE_00671 1.3e-159 S Alpha/beta hydrolase of unknown function (DUF915)
ICNLOFLE_00672 5.9e-79 F nucleoside 2-deoxyribosyltransferase
ICNLOFLE_00673 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
ICNLOFLE_00674 3.1e-63 S Domain of unknown function (DUF4430)
ICNLOFLE_00675 1.3e-88 S ECF transporter, substrate-specific component
ICNLOFLE_00676 9.2e-95 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
ICNLOFLE_00677 2.1e-271 nylA 3.5.1.4 J Belongs to the amidase family
ICNLOFLE_00678 2.5e-253 yjjP S Putative threonine/serine exporter
ICNLOFLE_00679 7e-59
ICNLOFLE_00680 2e-226 mesE M Transport protein ComB
ICNLOFLE_00681 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
ICNLOFLE_00683 7.7e-79 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
ICNLOFLE_00684 8.9e-131 plnD K LytTr DNA-binding domain
ICNLOFLE_00686 1.1e-41 spiA S Enterocin A Immunity
ICNLOFLE_00687 9e-22
ICNLOFLE_00691 1.7e-132 S CAAX protease self-immunity
ICNLOFLE_00692 2.7e-68 K Transcriptional regulator
ICNLOFLE_00693 1.4e-251 EGP Major Facilitator Superfamily
ICNLOFLE_00694 6.4e-54
ICNLOFLE_00695 1e-54 S Enterocin A Immunity
ICNLOFLE_00696 3e-181 S Aldo keto reductase
ICNLOFLE_00697 7.1e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ICNLOFLE_00698 1.1e-214 yqiG C Oxidoreductase
ICNLOFLE_00699 5.1e-16 S Short C-terminal domain
ICNLOFLE_00700 5.6e-253 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ICNLOFLE_00701 2.4e-128
ICNLOFLE_00702 2.3e-18
ICNLOFLE_00703 5.3e-279 mntH P H( )-stimulated, divalent metal cation uptake system
ICNLOFLE_00704 0.0 pacL P P-type ATPase
ICNLOFLE_00705 9.8e-64
ICNLOFLE_00706 2.5e-226 EGP Major Facilitator Superfamily
ICNLOFLE_00707 3.6e-309 mco Q Multicopper oxidase
ICNLOFLE_00708 1e-24
ICNLOFLE_00709 1.1e-104 2.5.1.105 P Cation efflux family
ICNLOFLE_00710 8.7e-51 czrA K Transcriptional regulator, ArsR family
ICNLOFLE_00711 5.4e-175 sitA P Belongs to the bacterial solute-binding protein 9 family
ICNLOFLE_00712 9.5e-145 mtsB U ABC 3 transport family
ICNLOFLE_00713 2.1e-129 mntB 3.6.3.35 P ABC transporter
ICNLOFLE_00714 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICNLOFLE_00715 3.8e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
ICNLOFLE_00716 9.3e-118 GM NmrA-like family
ICNLOFLE_00717 1.8e-84
ICNLOFLE_00718 3.5e-163 znuA P Belongs to the bacterial solute-binding protein 9 family
ICNLOFLE_00719 1.8e-19
ICNLOFLE_00720 5.3e-52
ICNLOFLE_00723 6.7e-23 S Protein of unknown function (DUF4065)
ICNLOFLE_00724 4.6e-50 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICNLOFLE_00725 3.1e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICNLOFLE_00726 2.1e-285 G MFS/sugar transport protein
ICNLOFLE_00727 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase concanavalin-like domain
ICNLOFLE_00728 1.6e-169 ssuA P NMT1-like family
ICNLOFLE_00729 1.6e-293 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
ICNLOFLE_00730 1.7e-232 yfiQ I Acyltransferase family
ICNLOFLE_00731 1.1e-119 ssuB P ATPases associated with a variety of cellular activities
ICNLOFLE_00732 3.9e-145 ssuC U Binding-protein-dependent transport system inner membrane component
ICNLOFLE_00733 3.8e-122 S B3/4 domain
ICNLOFLE_00734 0.0 V ABC transporter
ICNLOFLE_00735 0.0 V ATPases associated with a variety of cellular activities
ICNLOFLE_00736 1e-210 EGP Transmembrane secretion effector
ICNLOFLE_00737 5.7e-67 L PFAM Integrase catalytic region
ICNLOFLE_00738 7.9e-17 L Transposase DDE domain
ICNLOFLE_00739 6.5e-160 S PTS system sugar-specific permease component
ICNLOFLE_00740 1.9e-25 2.7.1.194 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ICNLOFLE_00741 2.2e-132 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
ICNLOFLE_00742 9.3e-67 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
ICNLOFLE_00743 6.6e-219 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
ICNLOFLE_00744 3.6e-210 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
ICNLOFLE_00745 2.1e-37 glvR K Helix-turn-helix domain, rpiR family
ICNLOFLE_00747 2.9e-19 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
ICNLOFLE_00748 1.2e-43 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
ICNLOFLE_00749 4.2e-52 5.4.2.6 S Haloacid dehalogenase-like hydrolase
ICNLOFLE_00750 2.5e-227 manR K PRD domain
ICNLOFLE_00751 1.4e-27 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
ICNLOFLE_00752 2.7e-166 4.1.2.13 G Fructose-bisphosphate aldolase class-II
ICNLOFLE_00753 7.7e-61 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_00754 4.7e-46 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_00755 9.4e-163 G Phosphotransferase System
ICNLOFLE_00756 2.8e-126 G Domain of unknown function (DUF4432)
ICNLOFLE_00757 2.8e-112 5.3.1.15 S Pfam:DUF1498
ICNLOFLE_00758 6.7e-196 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ICNLOFLE_00759 7.2e-61 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_00760 9e-268 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_00761 4e-191 malY 4.4.1.8 E Aminotransferase class I and II
ICNLOFLE_00762 2.2e-219 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_00763 9.6e-64 kdsD 5.3.1.13 M SIS domain
ICNLOFLE_00764 2.9e-44 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_00765 3e-31 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_00766 2.5e-183 ulaA 2.7.1.194 S PTS system sugar-specific permease component
ICNLOFLE_00767 1.6e-86 4.3.3.7 E Dihydrodipicolinate synthetase family
ICNLOFLE_00768 8.4e-71 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
ICNLOFLE_00769 9e-197 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_00770 1.9e-18 hxlR K Transcriptional regulator, HxlR family
ICNLOFLE_00771 3.3e-57 pnb C nitroreductase
ICNLOFLE_00772 2.5e-119
ICNLOFLE_00773 1.5e-07 K DNA-templated transcription, initiation
ICNLOFLE_00774 1.3e-17 S YvrJ protein family
ICNLOFLE_00775 4.3e-146 yqfZ 3.2.1.17 M hydrolase, family 25
ICNLOFLE_00776 7.4e-86 ygfC K Bacterial regulatory proteins, tetR family
ICNLOFLE_00777 7.2e-184 hrtB V ABC transporter permease
ICNLOFLE_00778 9.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
ICNLOFLE_00779 3.8e-262 npr 1.11.1.1 C NADH oxidase
ICNLOFLE_00780 9.1e-150 S hydrolase
ICNLOFLE_00781 2.2e-44 S Bacterial toxin of type II toxin-antitoxin system, YafQ
ICNLOFLE_00782 6.2e-137 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
ICNLOFLE_00785 3.5e-08
ICNLOFLE_00786 5.3e-78 L Resolvase, N-terminal
ICNLOFLE_00787 1.9e-217 tnpB L Putative transposase DNA-binding domain
ICNLOFLE_00789 3e-148 metQ_4 P Belongs to the nlpA lipoprotein family
ICNLOFLE_00790 1e-195 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
ICNLOFLE_00791 1.6e-174
ICNLOFLE_00792 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
ICNLOFLE_00793 9.4e-17
ICNLOFLE_00794 3.7e-102 K Bacterial regulatory proteins, tetR family
ICNLOFLE_00795 9.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
ICNLOFLE_00796 1.1e-98 dhaL 2.7.1.121 S Dak2
ICNLOFLE_00797 3.6e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
ICNLOFLE_00798 1.5e-76 ohr O OsmC-like protein
ICNLOFLE_00799 2.8e-120 V ATPases associated with a variety of cellular activities
ICNLOFLE_00800 8.2e-205
ICNLOFLE_00801 2.8e-41 tnp2PF3 L Transposase DDE domain
ICNLOFLE_00802 2.5e-86
ICNLOFLE_00803 3.5e-202 T PhoQ Sensor
ICNLOFLE_00804 1.6e-120 K Transcriptional regulatory protein, C terminal
ICNLOFLE_00805 2e-91 ogt 2.1.1.63 L Methyltransferase
ICNLOFLE_00806 1.1e-192 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICNLOFLE_00807 4.5e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_00808 2.6e-52 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
ICNLOFLE_00809 6.1e-85
ICNLOFLE_00810 7.2e-253 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICNLOFLE_00811 3.2e-291 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ICNLOFLE_00812 1.5e-132 K UTRA
ICNLOFLE_00813 5.9e-43
ICNLOFLE_00814 8.1e-58 ypaA S Protein of unknown function (DUF1304)
ICNLOFLE_00815 3e-54 S Protein of unknown function (DUF1516)
ICNLOFLE_00816 1.4e-254 pbuO S permease
ICNLOFLE_00817 9.6e-55 S DsrE/DsrF-like family
ICNLOFLE_00820 5.4e-138 tauB 3.6.3.36 P ATPases associated with a variety of cellular activities
ICNLOFLE_00821 2.6e-183 tauA P NMT1-like family
ICNLOFLE_00822 2.9e-142 tauC P Binding-protein-dependent transport system inner membrane component
ICNLOFLE_00823 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
ICNLOFLE_00824 3.6e-257 S Sulphur transport
ICNLOFLE_00825 4.4e-163 K LysR substrate binding domain
ICNLOFLE_00826 1.7e-192 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICNLOFLE_00827 2.7e-43
ICNLOFLE_00828 5.6e-106 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICNLOFLE_00829 0.0
ICNLOFLE_00831 2.2e-124 yqcC S WxL domain surface cell wall-binding
ICNLOFLE_00832 1.1e-184 ynjC S Cell surface protein
ICNLOFLE_00834 2.6e-272 L Mga helix-turn-helix domain
ICNLOFLE_00835 6.7e-176 yhaI S Protein of unknown function (DUF805)
ICNLOFLE_00836 9.4e-58
ICNLOFLE_00837 1.4e-253 rarA L recombination factor protein RarA
ICNLOFLE_00838 2.2e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICNLOFLE_00839 3.2e-133 K DeoR C terminal sensor domain
ICNLOFLE_00840 4.2e-286 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
ICNLOFLE_00841 6.4e-162 4.1.2.13 G Fructose-bisphosphate aldolase class-II
ICNLOFLE_00842 2.5e-242 sgaT 2.7.1.194 S PTS system sugar-specific permease component
ICNLOFLE_00843 6.7e-161 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
ICNLOFLE_00844 1.4e-138 magIII L Base excision DNA repair protein, HhH-GPD family
ICNLOFLE_00845 2.5e-256 bmr3 EGP Major facilitator Superfamily
ICNLOFLE_00846 3.6e-18
ICNLOFLE_00848 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
ICNLOFLE_00849 1.8e-303 oppA E ABC transporter, substratebinding protein
ICNLOFLE_00850 3.4e-65
ICNLOFLE_00851 4.5e-38 L PFAM Integrase catalytic region
ICNLOFLE_00852 1.2e-137 K UTRA domain
ICNLOFLE_00853 2.9e-256 fucA 3.2.1.51 GH29 G Alpha-L-fucosidase
ICNLOFLE_00854 3e-162 2.7.1.191 G PTS system sorbose subfamily IIB component
ICNLOFLE_00855 1e-129 G PTS system sorbose-specific iic component
ICNLOFLE_00856 4.5e-149 G PTS system mannose/fructose/sorbose family IID component
ICNLOFLE_00857 4e-289 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
ICNLOFLE_00858 3.2e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
ICNLOFLE_00859 2.1e-247 P Sodium:sulfate symporter transmembrane region
ICNLOFLE_00860 4.7e-160 K LysR substrate binding domain
ICNLOFLE_00861 1.2e-76
ICNLOFLE_00862 1.8e-72 K Transcriptional regulator
ICNLOFLE_00863 2.4e-248 ypiB EGP Major facilitator Superfamily
ICNLOFLE_00864 2.2e-89
ICNLOFLE_00865 2.7e-224 dgoD 4.2.1.6 M Mandelate racemase muconate lactonizing enzyme
ICNLOFLE_00866 5.1e-246 G PTS system sugar-specific permease component
ICNLOFLE_00867 1.2e-45 sgcB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_00868 1.1e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_00869 2.6e-112 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
ICNLOFLE_00870 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_00872 6e-49 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
ICNLOFLE_00873 3.5e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_00874 2.3e-297 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ICNLOFLE_00875 2.5e-161 ypbG 2.7.1.2 GK ROK family
ICNLOFLE_00876 1.5e-255 S Metal-independent alpha-mannosidase (GH125)
ICNLOFLE_00877 0.0 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
ICNLOFLE_00878 7.2e-278 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICNLOFLE_00879 5e-136 K UbiC transcription regulator-associated domain protein
ICNLOFLE_00880 1.1e-133 fcsR K DeoR C terminal sensor domain
ICNLOFLE_00881 7.5e-146 4.1.2.17, 4.1.2.19, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
ICNLOFLE_00882 6.4e-78 fucU 5.1.3.29 G RbsD / FucU transport protein family
ICNLOFLE_00883 1.8e-232 ywtG EGP Major facilitator Superfamily
ICNLOFLE_00884 8.5e-295 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 2.7.1.51 G FGGY family of carbohydrate kinases, N-terminal domain
ICNLOFLE_00885 0.0 fucI 5.3.1.25, 5.3.1.3 G Converts the aldose L-fucose into the corresponding ketose L-fuculose
ICNLOFLE_00886 8e-168 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
ICNLOFLE_00887 5.4e-258 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
ICNLOFLE_00888 1.3e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
ICNLOFLE_00889 2e-285 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
ICNLOFLE_00890 8.8e-227 iolF EGP Major facilitator Superfamily
ICNLOFLE_00891 4.1e-192 rhaR K helix_turn_helix, arabinose operon control protein
ICNLOFLE_00892 6.4e-215 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
ICNLOFLE_00893 1.4e-65 S Protein of unknown function (DUF1093)
ICNLOFLE_00894 1.3e-120
ICNLOFLE_00895 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
ICNLOFLE_00896 3.2e-193 pfoS S Phosphotransferase system, EIIC
ICNLOFLE_00897 6.2e-51 S MazG-like family
ICNLOFLE_00898 0.0 FbpA K Fibronectin-binding protein
ICNLOFLE_00900 3.2e-161 degV S EDD domain protein, DegV family
ICNLOFLE_00901 1.5e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
ICNLOFLE_00902 3.9e-209 hisC 2.6.1.9 E Cys/Met metabolism PLP-dependent enzyme
ICNLOFLE_00903 3.1e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ICNLOFLE_00904 2.4e-110 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
ICNLOFLE_00905 4.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ICNLOFLE_00906 1.7e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
ICNLOFLE_00907 1e-113 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICNLOFLE_00908 4e-136 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ICNLOFLE_00909 1.3e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
ICNLOFLE_00910 1.6e-57 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ICNLOFLE_00911 6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
ICNLOFLE_00912 5.2e-209 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICNLOFLE_00913 1.2e-149 Q Fumarylacetoacetate (FAA) hydrolase family
ICNLOFLE_00914 8.9e-113 nfnB 1.5.1.34 C Nitroreductase family
ICNLOFLE_00915 6.9e-71 K Acetyltransferase (GNAT) domain
ICNLOFLE_00916 5.4e-68 msi198 K Acetyltransferase (GNAT) domain
ICNLOFLE_00917 1.5e-222 EGP Transmembrane secretion effector
ICNLOFLE_00918 4.8e-128 T Transcriptional regulatory protein, C terminal
ICNLOFLE_00919 2.5e-175 T Histidine kinase-like ATPases
ICNLOFLE_00920 2.6e-135 XK27_05695 V ABC transporter, ATP-binding protein
ICNLOFLE_00921 0.0 ysaB V FtsX-like permease family
ICNLOFLE_00922 9.5e-211 xerS L Belongs to the 'phage' integrase family
ICNLOFLE_00923 3.6e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
ICNLOFLE_00924 1.8e-181 K LysR substrate binding domain
ICNLOFLE_00925 4.3e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICNLOFLE_00926 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
ICNLOFLE_00927 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICNLOFLE_00928 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICNLOFLE_00929 3.1e-110 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ICNLOFLE_00930 9.6e-174 lacX 5.1.3.3 G Aldose 1-epimerase
ICNLOFLE_00931 4.2e-256 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ICNLOFLE_00932 5.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ICNLOFLE_00933 1.2e-168 xerC D Belongs to the 'phage' integrase family. XerC subfamily
ICNLOFLE_00934 7.7e-252 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ICNLOFLE_00935 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICNLOFLE_00936 1.7e-148 dprA LU DNA protecting protein DprA
ICNLOFLE_00937 9.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICNLOFLE_00938 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ICNLOFLE_00939 5.9e-38 S Domain of unknown function (DUF4918)
ICNLOFLE_00940 3e-262 L Exonuclease
ICNLOFLE_00941 2.9e-44 relB L RelB antitoxin
ICNLOFLE_00942 1.2e-48 K Helix-turn-helix domain
ICNLOFLE_00943 9.6e-206 yceJ EGP Major facilitator Superfamily
ICNLOFLE_00944 8.9e-104 tag 3.2.2.20 L glycosylase
ICNLOFLE_00945 1.6e-32
ICNLOFLE_00946 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
ICNLOFLE_00947 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
ICNLOFLE_00948 2.6e-43
ICNLOFLE_00949 5.3e-152 V Beta-lactamase
ICNLOFLE_00950 1.6e-194 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
ICNLOFLE_00951 2.4e-141 H Protein of unknown function (DUF1698)
ICNLOFLE_00953 5.7e-143 puuD S peptidase C26
ICNLOFLE_00955 5.1e-259 6.3.1.2 E Glutamine synthetase N-terminal domain
ICNLOFLE_00956 3.7e-226 S Amidohydrolase
ICNLOFLE_00957 2.4e-248 E Amino acid permease
ICNLOFLE_00959 1e-75 K helix_turn_helix, mercury resistance
ICNLOFLE_00960 2.6e-163 morA2 S reductase
ICNLOFLE_00961 1.9e-197 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
ICNLOFLE_00962 4e-59 hxlR K Transcriptional regulator, HxlR family
ICNLOFLE_00963 1.5e-127 S membrane transporter protein
ICNLOFLE_00964 5.9e-200
ICNLOFLE_00965 1.2e-129 XK27_12140 V ATPases associated with a variety of cellular activities
ICNLOFLE_00966 2.5e-300 S Psort location CytoplasmicMembrane, score
ICNLOFLE_00967 7.5e-126 K Transcriptional regulatory protein, C terminal
ICNLOFLE_00968 1.3e-196 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
ICNLOFLE_00969 2.2e-157 V ATPases associated with a variety of cellular activities
ICNLOFLE_00970 2.2e-199
ICNLOFLE_00971 8e-106
ICNLOFLE_00972 1.7e-07
ICNLOFLE_00973 0.0 pepN 3.4.11.2 E aminopeptidase
ICNLOFLE_00974 2.4e-275 ycaM E amino acid
ICNLOFLE_00975 1.3e-238 G MFS/sugar transport protein
ICNLOFLE_00976 7.6e-91 S Protein of unknown function (DUF1440)
ICNLOFLE_00977 6.7e-161 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
ICNLOFLE_00978 2.7e-174 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ICNLOFLE_00980 4.2e-141
ICNLOFLE_00982 3e-212 metC 4.4.1.8 E cystathionine
ICNLOFLE_00983 2.8e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
ICNLOFLE_00984 1.4e-119 tcyB E ABC transporter
ICNLOFLE_00985 5e-117
ICNLOFLE_00986 1.9e-253 brnQ U Component of the transport system for branched-chain amino acids
ICNLOFLE_00987 1.1e-102 S WxL domain surface cell wall-binding
ICNLOFLE_00988 1.5e-173 S Cell surface protein
ICNLOFLE_00989 2.6e-45
ICNLOFLE_00990 1.7e-189 XK27_00720 S Leucine-rich repeat (LRR) protein
ICNLOFLE_00992 2.7e-169 yicL EG EamA-like transporter family
ICNLOFLE_00993 4e-301
ICNLOFLE_00994 2.7e-143 CcmA5 V ABC transporter
ICNLOFLE_00995 6.2e-78 S ECF-type riboflavin transporter, S component
ICNLOFLE_00996 1.2e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
ICNLOFLE_00997 1.7e-162 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
ICNLOFLE_00998 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ICNLOFLE_00999 0.0 XK27_09600 V ABC transporter, ATP-binding protein
ICNLOFLE_01000 0.0 V ABC transporter
ICNLOFLE_01001 4.7e-219 oxlT P Major Facilitator Superfamily
ICNLOFLE_01002 3.2e-127 treR K UTRA
ICNLOFLE_01003 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
ICNLOFLE_01004 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ICNLOFLE_01005 6.9e-213 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ICNLOFLE_01006 1.2e-269 yfnA E Amino Acid
ICNLOFLE_01007 1.6e-171 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
ICNLOFLE_01008 3.9e-251 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
ICNLOFLE_01009 4.6e-31 K 'Cold-shock' DNA-binding domain
ICNLOFLE_01010 1.5e-66
ICNLOFLE_01011 5.1e-75 O OsmC-like protein
ICNLOFLE_01012 2.3e-281 lsa S ABC transporter
ICNLOFLE_01013 1e-113 ylbE GM NAD(P)H-binding
ICNLOFLE_01014 3.4e-160 yeaE S Aldo/keto reductase family
ICNLOFLE_01015 2.1e-255 yifK E Amino acid permease
ICNLOFLE_01016 1.3e-283 S Protein of unknown function (DUF3800)
ICNLOFLE_01017 0.0 yjcE P Sodium proton antiporter
ICNLOFLE_01018 2.2e-56 S Protein of unknown function (DUF3021)
ICNLOFLE_01019 2.1e-68 K LytTr DNA-binding domain
ICNLOFLE_01020 1.2e-147 cylB V ABC-2 type transporter
ICNLOFLE_01021 5.7e-158 cylA V ABC transporter
ICNLOFLE_01022 3.5e-135 S Alpha/beta hydrolase of unknown function (DUF915)
ICNLOFLE_01023 1e-116 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
ICNLOFLE_01024 2.6e-52 ybjQ S Belongs to the UPF0145 family
ICNLOFLE_01025 1.4e-92 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
ICNLOFLE_01026 4.5e-158 3.5.1.10 C nadph quinone reductase
ICNLOFLE_01027 5.9e-244 amt P ammonium transporter
ICNLOFLE_01028 3.4e-177 yfeX P Peroxidase
ICNLOFLE_01029 1.5e-118 yhiD S MgtC family
ICNLOFLE_01030 3e-145 F DNA RNA non-specific endonuclease
ICNLOFLE_01032 3.9e-11
ICNLOFLE_01033 2.3e-311 ybiT S ABC transporter, ATP-binding protein
ICNLOFLE_01034 5.3e-274 mutS L ATPase domain of DNA mismatch repair MUTS family
ICNLOFLE_01035 5.8e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
ICNLOFLE_01036 1.9e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
ICNLOFLE_01037 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
ICNLOFLE_01038 5.9e-296 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICNLOFLE_01039 1.8e-133 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
ICNLOFLE_01041 6.5e-138 lacT K PRD domain
ICNLOFLE_01042 1.8e-173 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
ICNLOFLE_01043 9.7e-124 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
ICNLOFLE_01044 2.6e-245 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
ICNLOFLE_01045 2.5e-50 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
ICNLOFLE_01046 6.2e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ICNLOFLE_01047 5.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ICNLOFLE_01048 4.3e-280 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ICNLOFLE_01049 6.2e-161 K Transcriptional regulator
ICNLOFLE_01050 3.1e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
ICNLOFLE_01051 2.7e-10
ICNLOFLE_01053 4.4e-83 agaB 2.7.1.191 G PTS system sorbose subfamily IIB component
ICNLOFLE_01054 3.7e-124 agaC G PTS system sorbose-specific iic component
ICNLOFLE_01055 6.8e-134 G PTS system mannose/fructose/sorbose family IID component
ICNLOFLE_01056 5.5e-66 G PTS system fructose IIA component
ICNLOFLE_01057 4.5e-61
ICNLOFLE_01058 8.4e-97 S membrane transporter protein
ICNLOFLE_01059 1.2e-156 V Beta-lactamase
ICNLOFLE_01060 4e-111 S Domain of unknown function (DUF4867)
ICNLOFLE_01061 1.1e-162 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
ICNLOFLE_01062 1.8e-184 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
ICNLOFLE_01063 9.9e-94 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
ICNLOFLE_01064 6.1e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
ICNLOFLE_01065 1.9e-141 lacR K DeoR C terminal sensor domain
ICNLOFLE_01066 3.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
ICNLOFLE_01067 2.6e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ICNLOFLE_01068 0.0 sbcC L Putative exonuclease SbcCD, C subunit
ICNLOFLE_01069 1.3e-14
ICNLOFLE_01070 3.1e-86 hsp1 O Belongs to the small heat shock protein (HSP20) family
ICNLOFLE_01071 1.1e-210 mutY L A G-specific adenine glycosylase
ICNLOFLE_01072 1.9e-149 cytC6 I alpha/beta hydrolase fold
ICNLOFLE_01073 5.9e-121 yrkL S Flavodoxin-like fold
ICNLOFLE_01075 8.2e-88 S Short repeat of unknown function (DUF308)
ICNLOFLE_01076 3e-153 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICNLOFLE_01077 2.7e-199
ICNLOFLE_01078 3.9e-07
ICNLOFLE_01079 4e-116 ywnB S NmrA-like family
ICNLOFLE_01080 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
ICNLOFLE_01081 1e-165 XK27_00670 S ABC transporter substrate binding protein
ICNLOFLE_01082 1.8e-165 XK27_00670 S ABC transporter
ICNLOFLE_01083 2.9e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
ICNLOFLE_01084 5.2e-142 cmpC S ABC transporter, ATP-binding protein
ICNLOFLE_01085 1.4e-170 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
ICNLOFLE_01086 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
ICNLOFLE_01087 1.1e-181 ykcC GT2 M Glycosyl transferase family 2
ICNLOFLE_01088 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
ICNLOFLE_01089 3.2e-71 S GtrA-like protein
ICNLOFLE_01090 1.3e-128 K cheY-homologous receiver domain
ICNLOFLE_01091 3.9e-240 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
ICNLOFLE_01092 1.2e-67 yqkB S Belongs to the HesB IscA family
ICNLOFLE_01093 4.9e-122 drgA C Nitroreductase family
ICNLOFLE_01094 1e-204 lctO C IMP dehydrogenase / GMP reductase domain
ICNLOFLE_01097 1.2e-180 K sequence-specific DNA binding
ICNLOFLE_01098 3.1e-56 K Transcriptional regulator PadR-like family
ICNLOFLE_01099 4e-42 ygbF S Sugar efflux transporter for intercellular exchange
ICNLOFLE_01100 6.6e-50
ICNLOFLE_01101 2e-183 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
ICNLOFLE_01102 2.8e-55
ICNLOFLE_01103 3.4e-80
ICNLOFLE_01104 2.3e-207 yubA S AI-2E family transporter
ICNLOFLE_01105 7.4e-26
ICNLOFLE_01106 1e-97 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICNLOFLE_01107 8.8e-73
ICNLOFLE_01108 2.9e-168 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
ICNLOFLE_01109 7.9e-106 ywrF S Flavin reductase like domain
ICNLOFLE_01110 3.9e-96
ICNLOFLE_01111 5.2e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICNLOFLE_01112 3.3e-61 yeaO S Protein of unknown function, DUF488
ICNLOFLE_01113 8.6e-173 corA P CorA-like Mg2+ transporter protein
ICNLOFLE_01114 2.1e-160 mleR K LysR family
ICNLOFLE_01115 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
ICNLOFLE_01116 1.1e-170 mleP S Sodium Bile acid symporter family
ICNLOFLE_01117 8.3e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ICNLOFLE_01118 6.9e-95
ICNLOFLE_01119 1.8e-176 K sequence-specific DNA binding
ICNLOFLE_01120 2.9e-285 V ABC transporter transmembrane region
ICNLOFLE_01121 0.0 pepF E Oligopeptidase F
ICNLOFLE_01122 2.5e-77 ndk 2.7.4.6 F Belongs to the NDK family
ICNLOFLE_01123 1.1e-59
ICNLOFLE_01124 0.0 yfgQ P E1-E2 ATPase
ICNLOFLE_01125 4.8e-176 3.4.11.5 I Releases the N-terminal proline from various substrates
ICNLOFLE_01126 1.8e-59
ICNLOFLE_01127 3.4e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ICNLOFLE_01128 4.2e-193 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ICNLOFLE_01129 1e-119 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
ICNLOFLE_01130 1.5e-77 K Transcriptional regulator
ICNLOFLE_01131 8e-179 D Alpha beta
ICNLOFLE_01132 2.9e-84 nrdI F Belongs to the NrdI family
ICNLOFLE_01133 1.5e-157 dkgB S reductase
ICNLOFLE_01134 2e-119
ICNLOFLE_01135 1.1e-161 S Alpha beta hydrolase
ICNLOFLE_01136 1e-116 yviA S Protein of unknown function (DUF421)
ICNLOFLE_01137 2.3e-73 S Protein of unknown function (DUF3290)
ICNLOFLE_01138 3.5e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
ICNLOFLE_01139 1.6e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ICNLOFLE_01140 3.5e-103 yjbF S SNARE associated Golgi protein
ICNLOFLE_01141 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ICNLOFLE_01142 6.2e-196 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ICNLOFLE_01143 9.5e-208 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICNLOFLE_01144 1e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ICNLOFLE_01145 2.1e-49 yajC U Preprotein translocase
ICNLOFLE_01146 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
ICNLOFLE_01147 3.9e-116 sirR K Helix-turn-helix diphteria tox regulatory element
ICNLOFLE_01148 4.7e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICNLOFLE_01149 1.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICNLOFLE_01150 5.2e-240 ytoI K DRTGG domain
ICNLOFLE_01151 9.7e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
ICNLOFLE_01152 1.9e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ICNLOFLE_01153 1.5e-172
ICNLOFLE_01154 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICNLOFLE_01155 1e-209
ICNLOFLE_01156 4e-43 yrzL S Belongs to the UPF0297 family
ICNLOFLE_01157 9.5e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICNLOFLE_01158 2.3e-53 yrzB S Belongs to the UPF0473 family
ICNLOFLE_01159 2e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ICNLOFLE_01160 8.6e-93 cvpA S Colicin V production protein
ICNLOFLE_01161 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ICNLOFLE_01162 6.6e-53 trxA O Belongs to the thioredoxin family
ICNLOFLE_01163 4.2e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICNLOFLE_01164 1.8e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
ICNLOFLE_01165 4e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICNLOFLE_01166 1.8e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ICNLOFLE_01167 1.2e-82 yslB S Protein of unknown function (DUF2507)
ICNLOFLE_01168 5.3e-278 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ICNLOFLE_01169 6.9e-95 S Phosphoesterase
ICNLOFLE_01170 5.2e-133 gla U Major intrinsic protein
ICNLOFLE_01171 3e-84 ykuL S CBS domain
ICNLOFLE_01172 9.3e-156 XK27_00890 S Domain of unknown function (DUF368)
ICNLOFLE_01173 1.8e-156 ykuT M mechanosensitive ion channel
ICNLOFLE_01175 1.9e-78 ytxH S YtxH-like protein
ICNLOFLE_01176 5e-93 niaR S 3H domain
ICNLOFLE_01177 7.5e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ICNLOFLE_01178 2.3e-179 ccpA K catabolite control protein A
ICNLOFLE_01179 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
ICNLOFLE_01180 8.1e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
ICNLOFLE_01181 1.2e-135 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ICNLOFLE_01182 2.3e-270 pepV 3.5.1.18 E dipeptidase PepV
ICNLOFLE_01183 2.4e-256 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
ICNLOFLE_01184 2.1e-54
ICNLOFLE_01185 4.9e-188 yibE S overlaps another CDS with the same product name
ICNLOFLE_01186 5.9e-116 yibF S overlaps another CDS with the same product name
ICNLOFLE_01187 1.8e-115 S Calcineurin-like phosphoesterase
ICNLOFLE_01188 1.7e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
ICNLOFLE_01189 2.6e-109 yutD S Protein of unknown function (DUF1027)
ICNLOFLE_01190 2.2e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ICNLOFLE_01191 6.1e-114 S Protein of unknown function (DUF1461)
ICNLOFLE_01192 2.3e-116 dedA S SNARE-like domain protein
ICNLOFLE_01193 1.5e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
ICNLOFLE_01194 4.7e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
ICNLOFLE_01195 2.6e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICNLOFLE_01196 4.3e-64 yugI 5.3.1.9 J general stress protein
ICNLOFLE_01197 1e-257 wcaJ M Bacterial sugar transferase
ICNLOFLE_01198 5.4e-175 cps2D 5.1.3.2 M RmlD substrate binding domain
ICNLOFLE_01199 1.1e-110 glnP P ABC transporter permease
ICNLOFLE_01200 7.9e-109 gluC P ABC transporter permease
ICNLOFLE_01201 3.4e-149 glnH ET ABC transporter substrate-binding protein
ICNLOFLE_01202 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICNLOFLE_01203 3.4e-172
ICNLOFLE_01205 5.6e-85 zur P Belongs to the Fur family
ICNLOFLE_01206 1.8e-08
ICNLOFLE_01207 9.3e-112 gmk2 2.7.4.8 F Guanylate kinase
ICNLOFLE_01208 1.6e-67 K Acetyltransferase (GNAT) domain
ICNLOFLE_01209 3.6e-123 spl M NlpC/P60 family
ICNLOFLE_01210 2.7e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICNLOFLE_01211 6.4e-160 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICNLOFLE_01212 1.4e-53 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
ICNLOFLE_01213 3.3e-172 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ICNLOFLE_01214 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
ICNLOFLE_01215 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
ICNLOFLE_01216 1.5e-285 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
ICNLOFLE_01217 7.9e-200 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
ICNLOFLE_01218 1.7e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ICNLOFLE_01219 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ICNLOFLE_01220 6.1e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
ICNLOFLE_01221 4.8e-112 ylcC 3.4.22.70 M Sortase family
ICNLOFLE_01222 9.8e-144 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ICNLOFLE_01223 0.0 fbp 3.1.3.11 G phosphatase activity
ICNLOFLE_01224 1.8e-63 nrp 1.20.4.1 P ArsC family
ICNLOFLE_01225 0.0 clpL O associated with various cellular activities
ICNLOFLE_01226 7.6e-143 ywqE 3.1.3.48 GM PHP domain protein
ICNLOFLE_01227 1.2e-158 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ICNLOFLE_01228 4.4e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ICNLOFLE_01229 1.1e-80 L Transposase DDE domain
ICNLOFLE_01230 2.5e-180 L Integrase core domain
ICNLOFLE_01231 9.7e-103 L Bacterial dnaA protein
ICNLOFLE_01232 4.9e-77 cpsE M Bacterial sugar transferase
ICNLOFLE_01233 7.9e-84 2.4.1.166 GT2 M Glycosyltransferase like family 2
ICNLOFLE_01234 1.2e-74 sacB GT2,GT4 H Stealth protein CR1, conserved region 1
ICNLOFLE_01235 9.3e-28 L Transposase IS66 family
ICNLOFLE_01236 6.6e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
ICNLOFLE_01237 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICNLOFLE_01238 3.8e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICNLOFLE_01239 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICNLOFLE_01240 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ICNLOFLE_01241 1.3e-243 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ICNLOFLE_01242 4.7e-82 yabR J RNA binding
ICNLOFLE_01243 4.4e-65 divIC D cell cycle
ICNLOFLE_01244 1.8e-38 yabO J S4 domain protein
ICNLOFLE_01245 4.7e-280 yabM S Polysaccharide biosynthesis protein
ICNLOFLE_01246 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICNLOFLE_01247 2.4e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ICNLOFLE_01248 2e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICNLOFLE_01249 2e-263 S Putative peptidoglycan binding domain
ICNLOFLE_01250 1.3e-96 padR K Transcriptional regulator PadR-like family
ICNLOFLE_01251 6.1e-250 XK27_06930 S ABC-2 family transporter protein
ICNLOFLE_01252 6.8e-115 1.6.5.2 S Flavodoxin-like fold
ICNLOFLE_01253 5.1e-119 S (CBS) domain
ICNLOFLE_01254 2.7e-131 yciB M ErfK YbiS YcfS YnhG
ICNLOFLE_01255 7e-283 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
ICNLOFLE_01256 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
ICNLOFLE_01257 4.8e-88 S QueT transporter
ICNLOFLE_01258 1.9e-07
ICNLOFLE_01259 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
ICNLOFLE_01260 2.4e-37
ICNLOFLE_01261 6.3e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICNLOFLE_01262 1.7e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ICNLOFLE_01263 4.5e-264 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ICNLOFLE_01264 1.1e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ICNLOFLE_01265 2.3e-147
ICNLOFLE_01266 2.3e-124 S Tetratricopeptide repeat
ICNLOFLE_01267 2e-123
ICNLOFLE_01268 4.7e-73
ICNLOFLE_01269 3.3e-42 rpmE2 J Ribosomal protein L31
ICNLOFLE_01270 7.4e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICNLOFLE_01271 1.2e-09
ICNLOFLE_01272 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ICNLOFLE_01273 5.2e-97 L PFAM Integrase core domain
ICNLOFLE_01274 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
ICNLOFLE_01275 7e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICNLOFLE_01276 2.1e-103 K Bacterial regulatory proteins, tetR family
ICNLOFLE_01277 9.4e-184 yxeA V FtsX-like permease family
ICNLOFLE_01278 6e-126 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
ICNLOFLE_01279 6.4e-34
ICNLOFLE_01280 6.9e-136 tipA K TipAS antibiotic-recognition domain
ICNLOFLE_01282 5.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ICNLOFLE_01283 1.6e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICNLOFLE_01284 3.2e-158 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICNLOFLE_01285 1.8e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICNLOFLE_01286 1.4e-116
ICNLOFLE_01287 3.1e-60 rplQ J Ribosomal protein L17
ICNLOFLE_01288 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICNLOFLE_01289 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICNLOFLE_01290 2.1e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ICNLOFLE_01291 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
ICNLOFLE_01292 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ICNLOFLE_01293 1.4e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ICNLOFLE_01294 7.5e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ICNLOFLE_01295 1.1e-61 rplO J Binds to the 23S rRNA
ICNLOFLE_01296 1.7e-24 rpmD J Ribosomal protein L30
ICNLOFLE_01297 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICNLOFLE_01298 4.6e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICNLOFLE_01299 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICNLOFLE_01300 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICNLOFLE_01301 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICNLOFLE_01302 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICNLOFLE_01303 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICNLOFLE_01304 1.4e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICNLOFLE_01305 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
ICNLOFLE_01306 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICNLOFLE_01307 3.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICNLOFLE_01308 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICNLOFLE_01309 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICNLOFLE_01310 3.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICNLOFLE_01311 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ICNLOFLE_01312 5.9e-109 rplD J Forms part of the polypeptide exit tunnel
ICNLOFLE_01313 5.2e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICNLOFLE_01314 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
ICNLOFLE_01315 1.2e-68 psiE S Phosphate-starvation-inducible E
ICNLOFLE_01316 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
ICNLOFLE_01317 1.9e-197 yfjR K WYL domain
ICNLOFLE_01318 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICNLOFLE_01319 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ICNLOFLE_01320 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICNLOFLE_01321 6.9e-84 3.4.23.43
ICNLOFLE_01322 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICNLOFLE_01323 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICNLOFLE_01324 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ICNLOFLE_01325 3.6e-79 ctsR K Belongs to the CtsR family
ICNLOFLE_01336 4.9e-69 S COG NOG38524 non supervised orthologous group
ICNLOFLE_01339 7.9e-17 L Transposase DDE domain
ICNLOFLE_01340 1.7e-53
ICNLOFLE_01341 6.9e-136 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ICNLOFLE_01342 1.5e-166 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICNLOFLE_01343 1.1e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ICNLOFLE_01344 1.7e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ICNLOFLE_01345 5.3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ICNLOFLE_01346 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
ICNLOFLE_01347 1.6e-185 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICNLOFLE_01348 1.3e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICNLOFLE_01349 2.1e-61
ICNLOFLE_01350 3.9e-48 K sequence-specific DNA binding
ICNLOFLE_01351 9.1e-74 3.6.1.55 L NUDIX domain
ICNLOFLE_01352 1.9e-150 EG EamA-like transporter family
ICNLOFLE_01354 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
ICNLOFLE_01355 5.1e-70 rplI J Binds to the 23S rRNA
ICNLOFLE_01356 3.2e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ICNLOFLE_01357 2.1e-221
ICNLOFLE_01358 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ICNLOFLE_01359 1.1e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ICNLOFLE_01360 3.5e-199 4.2.1.126 S Bacterial protein of unknown function (DUF871)
ICNLOFLE_01361 3.6e-157 K Helix-turn-helix domain, rpiR family
ICNLOFLE_01362 1.8e-107 K Transcriptional regulator C-terminal region
ICNLOFLE_01363 4.9e-128 V ABC transporter, ATP-binding protein
ICNLOFLE_01364 0.0 ylbB V ABC transporter permease
ICNLOFLE_01365 1.2e-207 4.1.1.52 S Amidohydrolase
ICNLOFLE_01366 4.9e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICNLOFLE_01367 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
ICNLOFLE_01368 1.2e-55 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
ICNLOFLE_01369 2.4e-207 yxaM EGP Major facilitator Superfamily
ICNLOFLE_01370 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
ICNLOFLE_01371 5.5e-132
ICNLOFLE_01372 7.7e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICNLOFLE_01373 2.5e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ICNLOFLE_01374 4.2e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ICNLOFLE_01375 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
ICNLOFLE_01376 4.7e-171 ccpB 5.1.1.1 K lacI family
ICNLOFLE_01377 1.5e-68
ICNLOFLE_01378 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICNLOFLE_01379 1.5e-106 rsmC 2.1.1.172 J Methyltransferase
ICNLOFLE_01380 4.7e-49
ICNLOFLE_01381 7.5e-86 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ICNLOFLE_01382 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICNLOFLE_01383 1.5e-33 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICNLOFLE_01384 5.6e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ICNLOFLE_01385 8.7e-38 S Protein of unknown function (DUF2508)
ICNLOFLE_01386 7.4e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICNLOFLE_01387 7.8e-52 yaaQ S Cyclic-di-AMP receptor
ICNLOFLE_01388 8.2e-174 holB 2.7.7.7 L DNA polymerase III
ICNLOFLE_01389 1.7e-57 yabA L Involved in initiation control of chromosome replication
ICNLOFLE_01390 2.6e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ICNLOFLE_01391 1.1e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
ICNLOFLE_01392 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
ICNLOFLE_01393 7.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
ICNLOFLE_01394 6.1e-123
ICNLOFLE_01395 7e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
ICNLOFLE_01396 2.3e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
ICNLOFLE_01397 1.8e-187 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICNLOFLE_01398 3.6e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_01399 0.0 uup S ABC transporter, ATP-binding protein
ICNLOFLE_01400 4.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ICNLOFLE_01401 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
ICNLOFLE_01402 3.9e-159 ytrB V ABC transporter
ICNLOFLE_01403 1e-193
ICNLOFLE_01404 3.7e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ICNLOFLE_01405 4.2e-110 ydiL S CAAX protease self-immunity
ICNLOFLE_01406 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICNLOFLE_01407 4.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ICNLOFLE_01408 1.1e-83 L PFAM Integrase core domain
ICNLOFLE_01409 7.9e-17 L Transposase DDE domain
ICNLOFLE_01410 2.7e-52 L Helix-turn-helix domain
ICNLOFLE_01411 5.8e-79 L PFAM Integrase catalytic region
ICNLOFLE_01412 5.2e-124 L PFAM Integrase catalytic region
ICNLOFLE_01413 5.2e-231 EK Aminotransferase, class I
ICNLOFLE_01414 5.8e-166 K LysR substrate binding domain
ICNLOFLE_01415 3.6e-90 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICNLOFLE_01416 9.5e-152 yitU 3.1.3.104 S hydrolase
ICNLOFLE_01417 1.2e-126 yjhF G Phosphoglycerate mutase family
ICNLOFLE_01418 2.9e-117 yoaK S Protein of unknown function (DUF1275)
ICNLOFLE_01420 2.6e-54 V ABC transporter
ICNLOFLE_01421 1.9e-08
ICNLOFLE_01422 5.1e-28
ICNLOFLE_01423 2.7e-43
ICNLOFLE_01424 4.8e-12
ICNLOFLE_01425 1.2e-58
ICNLOFLE_01426 1.4e-142 S hydrolase
ICNLOFLE_01427 1.4e-192 yghZ C Aldo keto reductase family protein
ICNLOFLE_01428 0.0 uvrA3 L excinuclease ABC
ICNLOFLE_01429 3.6e-67 K MarR family
ICNLOFLE_01430 1.9e-110 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICNLOFLE_01431 2.9e-277 V ABC transporter transmembrane region
ICNLOFLE_01433 1.2e-109 S CAAX protease self-immunity
ICNLOFLE_01434 1.4e-130 ydfF K Transcriptional
ICNLOFLE_01435 8.4e-134 nodI V ABC transporter
ICNLOFLE_01436 2.9e-134 nodJ V ABC-2 type transporter
ICNLOFLE_01437 6.2e-174 shetA P Voltage-dependent anion channel
ICNLOFLE_01438 1.1e-147 rlrG K Transcriptional regulator
ICNLOFLE_01439 0.0 helD 3.6.4.12 L DNA helicase
ICNLOFLE_01441 4.9e-274 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ICNLOFLE_01442 3.3e-175 proV E ABC transporter, ATP-binding protein
ICNLOFLE_01443 1.6e-252 gshR 1.8.1.7 C Glutathione reductase
ICNLOFLE_01444 6.7e-32 EGP Major Facilitator Superfamily
ICNLOFLE_01445 9.2e-23 G Major facilitator Superfamily
ICNLOFLE_01446 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICNLOFLE_01447 3.1e-102 lemA S LemA family
ICNLOFLE_01448 3.3e-110 S TPM domain
ICNLOFLE_01449 7.9e-17 L Transposase DDE domain
ICNLOFLE_01450 1.3e-177
ICNLOFLE_01451 2.3e-110 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICNLOFLE_01452 1.2e-97 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICNLOFLE_01453 3.2e-154 nodB3 G Polysaccharide deacetylase
ICNLOFLE_01454 1.6e-238 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICNLOFLE_01455 3.7e-165 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
ICNLOFLE_01456 0.0 E amino acid
ICNLOFLE_01457 4e-136 cysA V ABC transporter, ATP-binding protein
ICNLOFLE_01458 0.0 V FtsX-like permease family
ICNLOFLE_01459 4.7e-171 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
ICNLOFLE_01460 1.2e-128 pgm3 G Phosphoglycerate mutase family
ICNLOFLE_01461 8.6e-184 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
ICNLOFLE_01462 3.1e-216 mntH P H( )-stimulated, divalent metal cation uptake system
ICNLOFLE_01463 1e-81 yjhE S Phage tail protein
ICNLOFLE_01464 9.2e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
ICNLOFLE_01465 0.0 yjbQ P TrkA C-terminal domain protein
ICNLOFLE_01466 6.8e-27
ICNLOFLE_01467 0.0 helD 3.6.4.12 L DNA helicase
ICNLOFLE_01468 2.3e-81 ykhA 3.1.2.20 I Thioesterase superfamily
ICNLOFLE_01469 5.7e-277 pipD E Dipeptidase
ICNLOFLE_01470 1.3e-42
ICNLOFLE_01471 4e-54
ICNLOFLE_01472 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
ICNLOFLE_01473 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ICNLOFLE_01476 1e-187
ICNLOFLE_01477 6e-17
ICNLOFLE_01478 5.4e-261 L Transposase IS66 family
ICNLOFLE_01479 2.8e-44 L PFAM IS66 Orf2 family protein
ICNLOFLE_01480 6.2e-42 L Transposase DDE domain
ICNLOFLE_01481 0.0 ydgH S MMPL family
ICNLOFLE_01482 2.7e-103 K Tetracycline repressor, C-terminal all-alpha domain
ICNLOFLE_01483 2.5e-122 S Sulfite exporter TauE/SafE
ICNLOFLE_01484 8.1e-249 3.5.4.28, 3.5.4.31 F Amidohydrolase family
ICNLOFLE_01485 1.9e-69 S An automated process has identified a potential problem with this gene model
ICNLOFLE_01486 2.5e-147 S Protein of unknown function (DUF3100)
ICNLOFLE_01488 1.9e-110 opuCD P Binding-protein-dependent transport system inner membrane component
ICNLOFLE_01489 1.6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ICNLOFLE_01490 4.7e-106 opuCB E ABC transporter permease
ICNLOFLE_01491 1.2e-214 opuCA E ABC transporter, ATP-binding protein
ICNLOFLE_01492 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
ICNLOFLE_01493 5.6e-33 copZ P Heavy-metal-associated domain
ICNLOFLE_01494 4.8e-97 dps P Belongs to the Dps family
ICNLOFLE_01495 2.4e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
ICNLOFLE_01497 4.3e-158 S CAAX protease self-immunity
ICNLOFLE_01499 5.5e-136 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
ICNLOFLE_01500 2.5e-228 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ICNLOFLE_01501 2.3e-102 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
ICNLOFLE_01502 4.7e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
ICNLOFLE_01503 7.2e-181 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICNLOFLE_01504 2.2e-219 S PTS system sugar-specific permease component
ICNLOFLE_01505 2.6e-38 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_01506 3.7e-57 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_01507 6e-33
ICNLOFLE_01509 7.5e-298 norB EGP Major Facilitator
ICNLOFLE_01510 3.5e-111 K Bacterial regulatory proteins, tetR family
ICNLOFLE_01511 8.6e-117
ICNLOFLE_01512 7.2e-159 S ABC-type transport system involved in multi-copper enzyme maturation permease component
ICNLOFLE_01513 1e-109
ICNLOFLE_01514 6.1e-99 V ATPases associated with a variety of cellular activities
ICNLOFLE_01515 6.2e-42 L Transposase DDE domain
ICNLOFLE_01517 7e-182 ybfG M peptidoglycan-binding domain-containing protein
ICNLOFLE_01518 4.5e-121 azlC E branched-chain amino acid
ICNLOFLE_01519 1.5e-50 azlD S Branched-chain amino acid transport protein (AzlD)
ICNLOFLE_01520 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
ICNLOFLE_01521 0.0 M Glycosyl hydrolase family 59
ICNLOFLE_01522 1.4e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
ICNLOFLE_01523 4.6e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
ICNLOFLE_01524 2.1e-279 uxaC 5.3.1.12 G glucuronate isomerase
ICNLOFLE_01525 1.1e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
ICNLOFLE_01526 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
ICNLOFLE_01527 7.8e-267 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
ICNLOFLE_01528 1.8e-229 G Major Facilitator
ICNLOFLE_01529 2e-126 kdgR K FCD domain
ICNLOFLE_01530 9.5e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
ICNLOFLE_01531 0.0 M Glycosyl hydrolase family 59
ICNLOFLE_01532 3.3e-58
ICNLOFLE_01533 2.9e-64 S pyridoxamine 5-phosphate
ICNLOFLE_01534 2.3e-243 EGP Major facilitator Superfamily
ICNLOFLE_01535 9e-220 3.1.1.83 I Alpha beta hydrolase
ICNLOFLE_01536 3.4e-118 K Bacterial regulatory proteins, tetR family
ICNLOFLE_01538 1e-39 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICNLOFLE_01539 6e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICNLOFLE_01540 3.6e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICNLOFLE_01541 2.2e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
ICNLOFLE_01542 1.1e-145 p75 M NlpC P60 family protein
ICNLOFLE_01543 1e-262 nox 1.6.3.4 C NADH oxidase
ICNLOFLE_01544 6.2e-162 sepS16B
ICNLOFLE_01545 1.1e-119
ICNLOFLE_01546 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
ICNLOFLE_01547 9.6e-239 malE G Bacterial extracellular solute-binding protein
ICNLOFLE_01548 1.7e-82
ICNLOFLE_01549 3.7e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
ICNLOFLE_01550 9e-130 XK27_08435 K UTRA
ICNLOFLE_01551 5.9e-219 agaS G SIS domain
ICNLOFLE_01552 4.1e-225 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICNLOFLE_01553 0.0 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
ICNLOFLE_01554 8.1e-82 manX_1 2.7.1.191 G PTS system sorbose subfamily IIB component
ICNLOFLE_01555 1.5e-140 XK27_08455 G PTS system sorbose-specific iic component
ICNLOFLE_01556 1.5e-144 manZ_1 G PTS system mannose/fructose/sorbose family IID component
ICNLOFLE_01557 7.8e-64 XK27_08465 2.7.1.191 G PTS system fructose IIA component
ICNLOFLE_01558 1e-173 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 F pfkB family carbohydrate kinase
ICNLOFLE_01559 5.4e-147 IQ KR domain
ICNLOFLE_01560 6.1e-244 gatC G PTS system sugar-specific permease component
ICNLOFLE_01561 6.2e-85 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_01562 1.5e-46 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_01563 2.8e-162
ICNLOFLE_01564 1.3e-41 2.4.1.52 GT4 M Glycosyl transferases group 1
ICNLOFLE_01565 5.8e-65 glfT1 1.1.1.133 S Glycosyltransferase like family 2
ICNLOFLE_01566 4e-25
ICNLOFLE_01567 2.5e-64 cps1D M Domain of unknown function (DUF4422)
ICNLOFLE_01568 2.8e-62 GT2,GT4 M Glycosyltransferase GT-D fold
ICNLOFLE_01569 9.3e-71 1.1.1.133 S Glycosyltransferase like family 2
ICNLOFLE_01570 4e-79 M Core-2/I-Branching enzyme
ICNLOFLE_01571 2.7e-210 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
ICNLOFLE_01572 1.4e-198 glf 5.4.99.9 M UDP-galactopyranose mutase
ICNLOFLE_01573 9.2e-109 ywqD 2.7.10.1 D Capsular exopolysaccharide family
ICNLOFLE_01574 9.8e-129 epsB M biosynthesis protein
ICNLOFLE_01575 4.1e-130 E lipolytic protein G-D-S-L family
ICNLOFLE_01576 1.4e-81 ccl S QueT transporter
ICNLOFLE_01577 7.1e-127 IQ Enoyl-(Acyl carrier protein) reductase
ICNLOFLE_01578 8.2e-37 XK27_01315 S Protein of unknown function (DUF2829)
ICNLOFLE_01579 5e-48 K Cro/C1-type HTH DNA-binding domain
ICNLOFLE_01580 3.3e-115 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
ICNLOFLE_01581 5.7e-175 oppF P Belongs to the ABC transporter superfamily
ICNLOFLE_01582 3e-190 oppD P Belongs to the ABC transporter superfamily
ICNLOFLE_01583 3.9e-171 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICNLOFLE_01584 7.3e-156 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICNLOFLE_01585 8.3e-256 oppA E ABC transporter, substratebinding protein
ICNLOFLE_01586 8.5e-277 oppA E ABC transporter, substratebinding protein
ICNLOFLE_01587 6.4e-207 EGP Major facilitator Superfamily
ICNLOFLE_01588 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICNLOFLE_01589 3.1e-130 yrjD S LUD domain
ICNLOFLE_01590 3.1e-289 lutB C 4Fe-4S dicluster domain
ICNLOFLE_01591 9.5e-149 lutA C Cysteine-rich domain
ICNLOFLE_01592 2.2e-102
ICNLOFLE_01593 9.5e-53 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
ICNLOFLE_01594 5.5e-211 S Bacterial protein of unknown function (DUF871)
ICNLOFLE_01595 2.7e-70 S Domain of unknown function (DUF3284)
ICNLOFLE_01596 4e-270 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICNLOFLE_01597 0.0 rafA 3.2.1.22 G alpha-galactosidase
ICNLOFLE_01598 2.4e-133 S Belongs to the UPF0246 family
ICNLOFLE_01599 5.3e-133 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
ICNLOFLE_01600 9.5e-294 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
ICNLOFLE_01601 3.9e-187 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
ICNLOFLE_01602 1.2e-111
ICNLOFLE_01603 9e-102 S WxL domain surface cell wall-binding
ICNLOFLE_01604 6e-146 frlD 2.7.1.218 G pfkB family carbohydrate kinase
ICNLOFLE_01605 3.5e-113 G Phosphodiester glycosidase
ICNLOFLE_01606 2.1e-153 G Phosphodiester glycosidase
ICNLOFLE_01607 2.7e-288 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
ICNLOFLE_01608 3.1e-206 S Protein of unknown function (DUF917)
ICNLOFLE_01609 8.4e-224 F Permease for cytosine/purines, uracil, thiamine, allantoin
ICNLOFLE_01610 7.6e-117
ICNLOFLE_01611 0.0 S Protein of unknown function (DUF1524)
ICNLOFLE_01612 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
ICNLOFLE_01613 0.0 S PglZ domain
ICNLOFLE_01614 2.5e-186 V site-specific DNA-methyltransferase (adenine-specific) activity
ICNLOFLE_01615 1.8e-190 L Belongs to the 'phage' integrase family
ICNLOFLE_01616 0.0 2.1.1.72 V Eco57I restriction-modification methylase
ICNLOFLE_01617 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
ICNLOFLE_01618 4.7e-92 S Domain of unknown function (DUF1788)
ICNLOFLE_01619 4.6e-103 S Putative inner membrane protein (DUF1819)
ICNLOFLE_01620 1.8e-204 ykiI
ICNLOFLE_01621 0.0 pip V domain protein
ICNLOFLE_01622 0.0 scrA 2.7.1.211 G phosphotransferase system
ICNLOFLE_01623 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
ICNLOFLE_01624 1.2e-177 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
ICNLOFLE_01625 3.5e-301 scrB 3.2.1.26 GH32 G invertase
ICNLOFLE_01627 1.3e-154 azoB GM NmrA-like family
ICNLOFLE_01628 9.4e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
ICNLOFLE_01629 3.8e-142 accA 2.1.3.15, 6.4.1.2 I alpha subunit
ICNLOFLE_01630 6.9e-150 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICNLOFLE_01631 2.8e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
ICNLOFLE_01632 1.2e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICNLOFLE_01633 2.3e-51 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ICNLOFLE_01634 3.1e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICNLOFLE_01635 7.3e-127 IQ reductase
ICNLOFLE_01636 1e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
ICNLOFLE_01637 2.4e-173 fabK 1.3.1.9 S Nitronate monooxygenase
ICNLOFLE_01638 4.5e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICNLOFLE_01639 2.6e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICNLOFLE_01640 2.1e-76 marR K Winged helix DNA-binding domain
ICNLOFLE_01641 9e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
ICNLOFLE_01642 8.2e-190 I carboxylic ester hydrolase activity
ICNLOFLE_01643 1.9e-225 bdhA C Iron-containing alcohol dehydrogenase
ICNLOFLE_01644 6e-61 P Rhodanese-like domain
ICNLOFLE_01645 9.8e-83 yetL K helix_turn_helix multiple antibiotic resistance protein
ICNLOFLE_01646 3.7e-67 K MarR family
ICNLOFLE_01647 7e-11 S response to antibiotic
ICNLOFLE_01648 2.4e-157 S Putative esterase
ICNLOFLE_01649 2.2e-183
ICNLOFLE_01650 1.2e-103 rmaB K Transcriptional regulator, MarR family
ICNLOFLE_01651 7.6e-85 F NUDIX domain
ICNLOFLE_01652 6.1e-175 U Major Facilitator Superfamily
ICNLOFLE_01653 3.2e-37 K helix_turn_helix, Arsenical Resistance Operon Repressor
ICNLOFLE_01654 3.5e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICNLOFLE_01655 4.4e-29
ICNLOFLE_01656 9.2e-123 S zinc-ribbon domain
ICNLOFLE_01657 1.8e-198 pbpX1 V Beta-lactamase
ICNLOFLE_01658 1.3e-180 K AI-2E family transporter
ICNLOFLE_01659 1.1e-127 srtA 3.4.22.70 M Sortase family
ICNLOFLE_01660 2.6e-65 gtcA S Teichoic acid glycosylation protein
ICNLOFLE_01661 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
ICNLOFLE_01662 5.6e-169 gbuC E glycine betaine
ICNLOFLE_01663 9.4e-126 proW E glycine betaine
ICNLOFLE_01664 2.2e-221 gbuA 3.6.3.32 E glycine betaine
ICNLOFLE_01665 4.7e-134 sfsA S Belongs to the SfsA family
ICNLOFLE_01666 1.1e-09
ICNLOFLE_01667 1.1e-67 usp1 T Universal stress protein family
ICNLOFLE_01668 1.6e-251 yxbA 6.3.1.12 S ATP-grasp enzyme
ICNLOFLE_01669 5.8e-155 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ICNLOFLE_01670 2e-283 thrC 4.2.3.1 E Threonine synthase
ICNLOFLE_01671 1.8e-231 hom 1.1.1.3 E homoserine dehydrogenase
ICNLOFLE_01672 8.7e-251 yclM 2.7.2.4 E Belongs to the aspartokinase family
ICNLOFLE_01673 4.7e-168 yqiK S SPFH domain / Band 7 family
ICNLOFLE_01674 1.3e-67
ICNLOFLE_01675 1.2e-154 pfoS S Phosphotransferase system, EIIC
ICNLOFLE_01676 7.8e-180 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICNLOFLE_01677 1.6e-216 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
ICNLOFLE_01678 5.6e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
ICNLOFLE_01679 3.8e-145 S Alpha/beta hydrolase family
ICNLOFLE_01680 3.3e-101 K Bacterial regulatory proteins, tetR family
ICNLOFLE_01681 1.9e-174 XK27_06930 V domain protein
ICNLOFLE_01682 5.3e-170 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICNLOFLE_01683 0.0 asnB 6.3.5.4 E Asparagine synthase
ICNLOFLE_01684 8.8e-206 S Calcineurin-like phosphoesterase
ICNLOFLE_01685 8.8e-162 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
ICNLOFLE_01686 5.1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICNLOFLE_01687 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICNLOFLE_01688 1.3e-165 natA S ABC transporter
ICNLOFLE_01689 3.2e-210 ysdA CP ABC-2 family transporter protein
ICNLOFLE_01690 2.4e-63 K helix_turn_helix gluconate operon transcriptional repressor
ICNLOFLE_01691 2.4e-161 CcmA V ABC transporter
ICNLOFLE_01692 7.4e-115 VPA0052 I ABC-2 family transporter protein
ICNLOFLE_01693 1.4e-144 IQ reductase
ICNLOFLE_01694 3.9e-257 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ICNLOFLE_01695 0.0 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ICNLOFLE_01696 1.7e-159 licT K CAT RNA binding domain
ICNLOFLE_01697 2.2e-288 cydC V ABC transporter transmembrane region
ICNLOFLE_01698 3.5e-310 cydD CO ABC transporter transmembrane region
ICNLOFLE_01699 4.9e-75 ynhH S NusG domain II
ICNLOFLE_01700 2.4e-174 M Peptidoglycan-binding domain 1 protein
ICNLOFLE_01701 8e-37 XK27_02675 K Acetyltransferase (GNAT) domain
ICNLOFLE_01702 5.1e-114 S CRISPR-associated protein (Cas_Csn2)
ICNLOFLE_01703 4.8e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ICNLOFLE_01704 2.1e-168 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ICNLOFLE_01705 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
ICNLOFLE_01706 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ICNLOFLE_01707 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
ICNLOFLE_01708 5e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
ICNLOFLE_01709 1.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
ICNLOFLE_01710 2e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
ICNLOFLE_01711 1e-171 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ICNLOFLE_01712 4.6e-38
ICNLOFLE_01713 4.9e-87
ICNLOFLE_01714 2.7e-24
ICNLOFLE_01715 1.5e-161 yicL EG EamA-like transporter family
ICNLOFLE_01716 1.5e-112 tag 3.2.2.20 L glycosylase
ICNLOFLE_01717 4.2e-77 usp5 T universal stress protein
ICNLOFLE_01718 4.7e-64 K Helix-turn-helix XRE-family like proteins
ICNLOFLE_01719 1.1e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
ICNLOFLE_01720 1.3e-223 queG 1.17.99.6 C Domain of unknown function (DUF1730)
ICNLOFLE_01721 1.4e-62
ICNLOFLE_01722 1.4e-87 bioY S BioY family
ICNLOFLE_01724 4.2e-102 Q methyltransferase
ICNLOFLE_01725 9.4e-101 T Sh3 type 3 domain protein
ICNLOFLE_01726 2.1e-114 yfeJ 6.3.5.2 F glutamine amidotransferase
ICNLOFLE_01727 8.8e-136 S Uncharacterized protein conserved in bacteria (DUF2263)
ICNLOFLE_01728 4.9e-257 yhdP S Transporter associated domain
ICNLOFLE_01729 1.9e-144 S Alpha beta hydrolase
ICNLOFLE_01730 7.8e-196 I Acyltransferase
ICNLOFLE_01731 2.6e-261 lmrB EGP Major facilitator Superfamily
ICNLOFLE_01732 1.5e-83 S Domain of unknown function (DUF4811)
ICNLOFLE_01733 9.4e-95 maf D nucleoside-triphosphate diphosphatase activity
ICNLOFLE_01734 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICNLOFLE_01735 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ICNLOFLE_01736 0.0 ydaO E amino acid
ICNLOFLE_01737 1.1e-56 S Domain of unknown function (DUF1827)
ICNLOFLE_01738 9.7e-272 L PFAM Integrase core domain
ICNLOFLE_01739 8.3e-221 ndh 1.6.99.3 C NADH dehydrogenase
ICNLOFLE_01742 8.4e-154 S Protein of unknown function (DUF1211)
ICNLOFLE_01743 5.9e-62 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ICNLOFLE_01744 3.5e-79 ywiB S Domain of unknown function (DUF1934)
ICNLOFLE_01745 4.6e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
ICNLOFLE_01746 3.3e-266 ywfO S HD domain protein
ICNLOFLE_01747 2.4e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
ICNLOFLE_01748 2e-178 S DUF218 domain
ICNLOFLE_01749 1.4e-60 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ICNLOFLE_01750 2.5e-77
ICNLOFLE_01751 3.2e-53 nudA S ASCH
ICNLOFLE_01752 2.3e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICNLOFLE_01753 5.1e-214 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICNLOFLE_01754 7.6e-222 ysaA V RDD family
ICNLOFLE_01755 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
ICNLOFLE_01756 6.5e-119 ybbL S ABC transporter, ATP-binding protein
ICNLOFLE_01757 1.8e-123 ybbM S Uncharacterised protein family (UPF0014)
ICNLOFLE_01758 6.7e-159 czcD P cation diffusion facilitator family transporter
ICNLOFLE_01759 1.4e-164 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICNLOFLE_01760 1.1e-37 veg S Biofilm formation stimulator VEG
ICNLOFLE_01761 1.3e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ICNLOFLE_01762 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ICNLOFLE_01763 4.7e-148 tatD L hydrolase, TatD family
ICNLOFLE_01764 1.1e-78 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
ICNLOFLE_01765 3.3e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
ICNLOFLE_01766 1.1e-172 yqhA G Aldose 1-epimerase
ICNLOFLE_01767 7.8e-126 T LytTr DNA-binding domain
ICNLOFLE_01768 5.6e-169 2.7.13.3 T GHKL domain
ICNLOFLE_01769 0.0 V ABC transporter
ICNLOFLE_01770 0.0 V ABC transporter
ICNLOFLE_01771 1.1e-30 K Transcriptional
ICNLOFLE_01772 1.2e-68
ICNLOFLE_01773 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICNLOFLE_01774 2.4e-173 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
ICNLOFLE_01776 1.9e-152 yunF F Protein of unknown function DUF72
ICNLOFLE_01777 3.8e-92 3.6.1.55 F NUDIX domain
ICNLOFLE_01778 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ICNLOFLE_01779 9e-107 yiiE S Protein of unknown function (DUF1211)
ICNLOFLE_01780 2.2e-128 cobB K Sir2 family
ICNLOFLE_01781 2.8e-17
ICNLOFLE_01782 4.4e-169
ICNLOFLE_01783 3.8e-98 yxkA S Phosphatidylethanolamine-binding protein
ICNLOFLE_01785 4.2e-162 ypuA S Protein of unknown function (DUF1002)
ICNLOFLE_01786 1.3e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICNLOFLE_01787 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ICNLOFLE_01788 9.5e-286 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ICNLOFLE_01789 3e-173 S Aldo keto reductase
ICNLOFLE_01790 9.3e-155 bioC 2.1.1.187, 2.1.1.197 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
ICNLOFLE_01791 4.8e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
ICNLOFLE_01792 3.5e-239 dinF V MatE
ICNLOFLE_01793 1.9e-55
ICNLOFLE_01794 3.1e-150 recO L Involved in DNA repair and RecF pathway recombination
ICNLOFLE_01795 9.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICNLOFLE_01796 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
ICNLOFLE_01797 1.5e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
ICNLOFLE_01798 8.2e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICNLOFLE_01799 7.7e-180 phoH T phosphate starvation-inducible protein PhoH
ICNLOFLE_01800 1.6e-68 yqeY S YqeY-like protein
ICNLOFLE_01801 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
ICNLOFLE_01802 7.2e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
ICNLOFLE_01803 1.1e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ICNLOFLE_01804 4.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ICNLOFLE_01805 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ICNLOFLE_01806 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
ICNLOFLE_01807 1.4e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
ICNLOFLE_01808 3e-276
ICNLOFLE_01809 1.6e-160 V ABC transporter
ICNLOFLE_01810 1.2e-82 FG adenosine 5'-monophosphoramidase activity
ICNLOFLE_01811 2.3e-248 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
ICNLOFLE_01812 3.4e-117 3.1.3.18 J HAD-hyrolase-like
ICNLOFLE_01813 3.6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ICNLOFLE_01814 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICNLOFLE_01815 3.7e-54
ICNLOFLE_01816 3.5e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ICNLOFLE_01817 3.5e-174 prmA J Ribosomal protein L11 methyltransferase
ICNLOFLE_01818 3.6e-85 XK27_03960 S Protein of unknown function (DUF3013)
ICNLOFLE_01819 3.2e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
ICNLOFLE_01820 3.1e-37
ICNLOFLE_01821 2.7e-64 S Protein of unknown function (DUF1093)
ICNLOFLE_01822 2.3e-26
ICNLOFLE_01823 5.7e-62
ICNLOFLE_01825 9.2e-112 1.6.5.2 S Flavodoxin-like fold
ICNLOFLE_01826 2.1e-94 K Bacterial regulatory proteins, tetR family
ICNLOFLE_01827 9.6e-138 4.1.2.14 S KDGP aldolase
ICNLOFLE_01828 9.1e-206 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
ICNLOFLE_01829 2e-216 dho 3.5.2.3 S Amidohydrolase family
ICNLOFLE_01830 3.6e-107 S Domain of unknown function (DUF4310)
ICNLOFLE_01831 1.7e-137 S Domain of unknown function (DUF4311)
ICNLOFLE_01832 6e-53 S Domain of unknown function (DUF4312)
ICNLOFLE_01833 1.2e-61 S Glycine-rich SFCGS
ICNLOFLE_01834 3.6e-55 S PRD domain
ICNLOFLE_01835 0.0 K Mga helix-turn-helix domain
ICNLOFLE_01836 4.5e-123 tal 2.2.1.2 H Pfam:Transaldolase
ICNLOFLE_01837 4.1e-65 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
ICNLOFLE_01838 1.1e-195 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
ICNLOFLE_01839 2.2e-102 srlA G PTS system enzyme II sorbitol-specific factor
ICNLOFLE_01840 1.2e-88 gutM K Glucitol operon activator protein (GutM)
ICNLOFLE_01841 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
ICNLOFLE_01842 2.2e-145 IQ NAD dependent epimerase/dehydratase family
ICNLOFLE_01843 2.5e-24 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
ICNLOFLE_01844 1.5e-29 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
ICNLOFLE_01845 1.9e-135 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
ICNLOFLE_01846 4.1e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
ICNLOFLE_01847 2.1e-168 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
ICNLOFLE_01848 4.9e-137 repA K DeoR C terminal sensor domain
ICNLOFLE_01849 7.4e-115 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
ICNLOFLE_01850 3.7e-45 sgaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_01851 5.3e-281 ulaA S PTS system sugar-specific permease component
ICNLOFLE_01852 3.2e-80 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_01853 1.2e-213 ulaG S Beta-lactamase superfamily domain
ICNLOFLE_01854 7e-187 S Cell surface protein
ICNLOFLE_01856 3.8e-137 S WxL domain surface cell wall-binding
ICNLOFLE_01857 0.0 N domain, Protein
ICNLOFLE_01858 6.7e-260 K Mga helix-turn-helix domain
ICNLOFLE_01859 9.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
ICNLOFLE_01860 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
ICNLOFLE_01862 1.4e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICNLOFLE_01863 7.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ICNLOFLE_01865 4.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ICNLOFLE_01866 1.2e-148 ytmP 2.7.1.89 M Choline/ethanolamine kinase
ICNLOFLE_01867 3.1e-223 ecsB U ABC transporter
ICNLOFLE_01868 4.9e-131 ecsA V ABC transporter, ATP-binding protein
ICNLOFLE_01869 7.2e-74 hit FG histidine triad
ICNLOFLE_01870 7.4e-48 yhaH S YtxH-like protein
ICNLOFLE_01871 1.3e-157 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ICNLOFLE_01872 6.2e-182 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICNLOFLE_01873 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
ICNLOFLE_01874 4.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICNLOFLE_01875 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ICNLOFLE_01876 9.7e-100 yqaB S Acetyltransferase (GNAT) domain
ICNLOFLE_01877 7.7e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
ICNLOFLE_01878 2.1e-304 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
ICNLOFLE_01879 8.6e-292 2.4.1.52 GT4 M Glycosyl transferases group 1
ICNLOFLE_01880 6.8e-28
ICNLOFLE_01881 8.2e-228
ICNLOFLE_01882 1.6e-222 yceI G Sugar (and other) transporter
ICNLOFLE_01883 3.1e-90
ICNLOFLE_01884 6.5e-156 K acetyltransferase
ICNLOFLE_01885 9.8e-225 mdtG EGP Major facilitator Superfamily
ICNLOFLE_01886 4.5e-38 L PFAM Integrase catalytic region
ICNLOFLE_01887 4.8e-162 tas C Aldo/keto reductase family
ICNLOFLE_01888 1.8e-44 S Enterocin A Immunity
ICNLOFLE_01889 1.5e-121
ICNLOFLE_01890 7.3e-133
ICNLOFLE_01891 1.4e-56 K Transcriptional regulator PadR-like family
ICNLOFLE_01892 8.6e-103 K Helix-turn-helix XRE-family like proteins
ICNLOFLE_01893 3.9e-192 MA20_36090 S Protein of unknown function (DUF2974)
ICNLOFLE_01894 5.4e-228 N Uncharacterized conserved protein (DUF2075)
ICNLOFLE_01895 9.6e-103
ICNLOFLE_01896 0.0 M domain protein
ICNLOFLE_01897 1.7e-262 M domain protein
ICNLOFLE_01898 3.5e-288 M Cna protein B-type domain
ICNLOFLE_01899 2.6e-133 3.4.22.70 M Sortase family
ICNLOFLE_01900 3.3e-92
ICNLOFLE_01902 1e-148 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICNLOFLE_01903 6.3e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICNLOFLE_01904 4.9e-224 pimH EGP Major facilitator Superfamily
ICNLOFLE_01905 1.9e-58 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICNLOFLE_01906 6.2e-42 L Transposase DDE domain
ICNLOFLE_01907 8.5e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
ICNLOFLE_01908 3.7e-137 G PTS system sorbose-specific iic component
ICNLOFLE_01909 1.3e-151 manZ G PTS system mannose/fructose/sorbose family IID component
ICNLOFLE_01910 1.2e-204 C Zinc-binding dehydrogenase
ICNLOFLE_01911 2.1e-279 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
ICNLOFLE_01912 2.7e-97 S Domain of unknown function (DUF4428)
ICNLOFLE_01913 5.4e-208 3.2.1.51 GH29 G Alpha-L-fucosidase
ICNLOFLE_01914 5.3e-215 uhpT EGP Major facilitator Superfamily
ICNLOFLE_01915 2.2e-131 ymfC K UTRA
ICNLOFLE_01916 5.2e-256 3.5.1.18 E Peptidase family M20/M25/M40
ICNLOFLE_01917 1.4e-181 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
ICNLOFLE_01918 1.8e-159 bglK_1 GK ROK family
ICNLOFLE_01919 1.7e-44
ICNLOFLE_01920 0.0 O Belongs to the peptidase S8 family
ICNLOFLE_01921 5.9e-53
ICNLOFLE_01922 1.3e-85
ICNLOFLE_01923 8.9e-105 S Membrane
ICNLOFLE_01924 8.1e-287 pipD E Dipeptidase
ICNLOFLE_01925 3.8e-54
ICNLOFLE_01926 5e-113 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
ICNLOFLE_01927 8e-103 S Protein of unknown function (DUF1211)
ICNLOFLE_01928 1.2e-127 S membrane transporter protein
ICNLOFLE_01929 2.9e-153 supH G Sucrose-6F-phosphate phosphohydrolase
ICNLOFLE_01930 3e-96 K transcriptional regulator
ICNLOFLE_01931 2.4e-127 macB V ABC transporter, ATP-binding protein
ICNLOFLE_01932 0.0 ylbB V ABC transporter permease
ICNLOFLE_01933 6.9e-125 usp 3.5.1.28 CBM50 D CHAP domain
ICNLOFLE_01934 7e-203 P Pyridine nucleotide-disulphide oxidoreductase
ICNLOFLE_01935 1.1e-190 amtB P Ammonium Transporter Family
ICNLOFLE_01936 4.6e-118 ybhL S Inhibitor of apoptosis-promoting Bax1
ICNLOFLE_01937 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICNLOFLE_01938 3.2e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ICNLOFLE_01939 2.3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ICNLOFLE_01940 3.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICNLOFLE_01941 1.3e-251 dnaB L replication initiation and membrane attachment
ICNLOFLE_01942 2.2e-168 dnaI L Primosomal protein DnaI
ICNLOFLE_01943 8.4e-226 V regulation of methylation-dependent chromatin silencing
ICNLOFLE_01944 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICNLOFLE_01945 1.9e-65
ICNLOFLE_01946 1.3e-128 S SseB protein N-terminal domain
ICNLOFLE_01947 3.4e-137 cobB K Sir2 family
ICNLOFLE_01948 1.8e-235 EGP Major Facilitator Superfamily
ICNLOFLE_01949 6.2e-42 L Transposase DDE domain
ICNLOFLE_01950 5.3e-80 perR P Belongs to the Fur family
ICNLOFLE_01951 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ICNLOFLE_01952 5.1e-44 ykuJ S Protein of unknown function (DUF1797)
ICNLOFLE_01953 1.8e-220 patA 2.6.1.1 E Aminotransferase
ICNLOFLE_01954 6.9e-168 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICNLOFLE_01955 2.7e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
ICNLOFLE_01956 1.5e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
ICNLOFLE_01957 6.5e-298 ybeC E amino acid
ICNLOFLE_01958 1.3e-93 sigH K Sigma-70 region 2
ICNLOFLE_01984 1.9e-164 corA P CorA-like Mg2+ transporter protein
ICNLOFLE_01985 4.1e-37 mntH P metal ion transmembrane transporter activity
ICNLOFLE_01986 6.4e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICNLOFLE_01987 4.9e-59 M Cna protein B-type domain
ICNLOFLE_01988 6.2e-257 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
ICNLOFLE_01989 0.0 L MobA MobL family protein
ICNLOFLE_01990 1.5e-24
ICNLOFLE_01991 8.9e-41
ICNLOFLE_01992 1.6e-85
ICNLOFLE_01993 8.7e-44 relB L Addiction module antitoxin, RelB DinJ family
ICNLOFLE_01994 1.6e-165 repA S Replication initiator protein A
ICNLOFLE_01995 9.1e-32 yxaB GM Polysaccharide pyruvyl transferase
ICNLOFLE_01996 2.8e-66 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ICNLOFLE_01997 1.7e-55 ypaA S Protein of unknown function (DUF1304)
ICNLOFLE_01998 9.1e-11 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
ICNLOFLE_01999 1.8e-33 tnp2PF3 L Transposase DDE domain
ICNLOFLE_02000 1.1e-65 tnp2PF3 L Transposase DDE domain
ICNLOFLE_02001 1.2e-47 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICNLOFLE_02002 6.9e-72 K Transcriptional regulator
ICNLOFLE_02003 8.9e-78 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICNLOFLE_02004 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
ICNLOFLE_02005 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICNLOFLE_02006 7.7e-100 yvdD 3.2.2.10 S Belongs to the LOG family
ICNLOFLE_02007 7.6e-180 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
ICNLOFLE_02008 1.8e-121 mhqD S Dienelactone hydrolase family
ICNLOFLE_02009 7.3e-191 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICNLOFLE_02010 3.6e-168 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICNLOFLE_02011 2.4e-95 yqeG S HAD phosphatase, family IIIA
ICNLOFLE_02012 1.8e-217 yqeH S Ribosome biogenesis GTPase YqeH
ICNLOFLE_02013 6.4e-48 yhbY J RNA-binding protein
ICNLOFLE_02014 9.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICNLOFLE_02015 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
ICNLOFLE_02016 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ICNLOFLE_02017 3.1e-141 yqeM Q Methyltransferase
ICNLOFLE_02018 1.5e-211 ylbM S Belongs to the UPF0348 family
ICNLOFLE_02019 1.6e-97 yceD S Uncharacterized ACR, COG1399
ICNLOFLE_02021 4.6e-17 yhcX S Psort location Cytoplasmic, score
ICNLOFLE_02022 2.2e-237 L Probable transposase
ICNLOFLE_02023 1.5e-140 M Peptidase family M23
ICNLOFLE_02024 7.2e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ICNLOFLE_02025 7.9e-123 K response regulator
ICNLOFLE_02026 1.1e-289 arlS 2.7.13.3 T Histidine kinase
ICNLOFLE_02027 4.5e-180 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICNLOFLE_02028 2.4e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
ICNLOFLE_02029 2.4e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICNLOFLE_02030 5.6e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
ICNLOFLE_02031 6.9e-68 yodB K Transcriptional regulator, HxlR family
ICNLOFLE_02032 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICNLOFLE_02033 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICNLOFLE_02034 1e-207 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICNLOFLE_02035 1.2e-114 udk 2.7.1.48 F Cytidine monophosphokinase
ICNLOFLE_02036 9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICNLOFLE_02037 2.3e-122 yvqF S Cell wall-active antibiotics response 4TMS YvqF
ICNLOFLE_02038 6.1e-183 vraS 2.7.13.3 T Histidine kinase
ICNLOFLE_02039 2e-115 vraR K helix_turn_helix, Lux Regulon
ICNLOFLE_02040 2.9e-53 yneR S Belongs to the HesB IscA family
ICNLOFLE_02041 0.0 S Bacterial membrane protein YfhO
ICNLOFLE_02042 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
ICNLOFLE_02043 8.7e-122 gluP 3.4.21.105 S Peptidase, S54 family
ICNLOFLE_02044 1.1e-40 yqgQ S Bacterial protein of unknown function (DUF910)
ICNLOFLE_02045 2.4e-178 glk 2.7.1.2 G Glucokinase
ICNLOFLE_02046 3.7e-72 yqhL P Rhodanese-like protein
ICNLOFLE_02047 4.4e-25 WQ51_02665 S Protein of unknown function (DUF3042)
ICNLOFLE_02048 4.7e-182 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICNLOFLE_02049 5.3e-242 ynbB 4.4.1.1 P aluminum resistance
ICNLOFLE_02050 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
ICNLOFLE_02051 1e-60 glnR K Transcriptional regulator
ICNLOFLE_02052 5.8e-263 glnA 6.3.1.2 E glutamine synthetase
ICNLOFLE_02053 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
ICNLOFLE_02054 4.2e-300 V ABC transporter transmembrane region
ICNLOFLE_02056 2.5e-233 ywhK S Membrane
ICNLOFLE_02057 4.1e-14
ICNLOFLE_02058 3.8e-32
ICNLOFLE_02059 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
ICNLOFLE_02060 2.7e-55 ysxB J Cysteine protease Prp
ICNLOFLE_02061 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
ICNLOFLE_02062 7e-203 ypdF 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ICNLOFLE_02063 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICNLOFLE_02064 2e-77 yqhY S Asp23 family, cell envelope-related function
ICNLOFLE_02065 2e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICNLOFLE_02066 5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICNLOFLE_02067 1e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICNLOFLE_02068 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICNLOFLE_02069 9.4e-150 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICNLOFLE_02070 3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
ICNLOFLE_02071 2e-74 argR K Regulates arginine biosynthesis genes
ICNLOFLE_02072 6.1e-310 recN L May be involved in recombinational repair of damaged DNA
ICNLOFLE_02073 6e-51
ICNLOFLE_02074 2.1e-123 rssA S Patatin-like phospholipase
ICNLOFLE_02075 3.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
ICNLOFLE_02076 2.9e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ICNLOFLE_02077 7.3e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICNLOFLE_02078 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICNLOFLE_02079 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICNLOFLE_02080 7.8e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICNLOFLE_02081 1.5e-135 stp 3.1.3.16 T phosphatase
ICNLOFLE_02082 0.0 KLT serine threonine protein kinase
ICNLOFLE_02083 6e-171 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ICNLOFLE_02084 1.5e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
ICNLOFLE_02085 6.7e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
ICNLOFLE_02086 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
ICNLOFLE_02087 2.3e-57 asp S Asp23 family, cell envelope-related function
ICNLOFLE_02088 1.3e-309 yloV S DAK2 domain fusion protein YloV
ICNLOFLE_02089 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICNLOFLE_02090 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ICNLOFLE_02091 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICNLOFLE_02092 4.4e-194 oppD P Belongs to the ABC transporter superfamily
ICNLOFLE_02093 1.4e-178 oppF P Belongs to the ABC transporter superfamily
ICNLOFLE_02094 2.8e-174 oppB P ABC transporter permease
ICNLOFLE_02095 8.2e-136 oppC EP Binding-protein-dependent transport system inner membrane component
ICNLOFLE_02096 0.0 oppA1 E ABC transporter substrate-binding protein
ICNLOFLE_02097 7.7e-126 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ICNLOFLE_02098 0.0 smc D Required for chromosome condensation and partitioning
ICNLOFLE_02099 5.7e-183 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ICNLOFLE_02100 8.8e-53
ICNLOFLE_02101 5.6e-26
ICNLOFLE_02102 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ICNLOFLE_02103 3.1e-230 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICNLOFLE_02104 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ICNLOFLE_02105 8.4e-38 ylqC S Belongs to the UPF0109 family
ICNLOFLE_02106 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICNLOFLE_02107 1.6e-148 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ICNLOFLE_02108 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ICNLOFLE_02109 1.1e-25
ICNLOFLE_02110 1.1e-37 ynzC S UPF0291 protein
ICNLOFLE_02111 4.8e-29 yneF S UPF0154 protein
ICNLOFLE_02112 0.0 mdlA V ABC transporter
ICNLOFLE_02113 0.0 mdlB V ABC transporter
ICNLOFLE_02114 2.6e-138 yejC S Protein of unknown function (DUF1003)
ICNLOFLE_02115 9.1e-203 bcaP E Amino Acid
ICNLOFLE_02116 1.5e-123 plsC 2.3.1.51 I Acyltransferase
ICNLOFLE_02117 4.8e-134 yabB 2.1.1.223 L Methyltransferase small domain
ICNLOFLE_02118 1.3e-47 yazA L GIY-YIG catalytic domain protein
ICNLOFLE_02119 1.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
ICNLOFLE_02120 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ICNLOFLE_02121 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ICNLOFLE_02122 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ICNLOFLE_02123 1.7e-139 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICNLOFLE_02124 1.6e-140 cdsA 2.7.7.41 S Belongs to the CDS family
ICNLOFLE_02125 1.1e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
ICNLOFLE_02126 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ICNLOFLE_02127 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICNLOFLE_02128 1e-84 rimP J Required for maturation of 30S ribosomal subunits
ICNLOFLE_02129 7.9e-211 nusA K Participates in both transcription termination and antitermination
ICNLOFLE_02130 1.5e-46 ylxR K Protein of unknown function (DUF448)
ICNLOFLE_02131 5.4e-44 ylxQ J ribosomal protein
ICNLOFLE_02132 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICNLOFLE_02133 4.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICNLOFLE_02134 6.7e-119 terC P membrane
ICNLOFLE_02135 1.7e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ICNLOFLE_02136 1.3e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
ICNLOFLE_02137 1.1e-225 hemN H Involved in the biosynthesis of porphyrin-containing compound
ICNLOFLE_02139 8.4e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ICNLOFLE_02140 1.4e-99 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICNLOFLE_02141 1e-286 dnaK O Heat shock 70 kDa protein
ICNLOFLE_02142 4.1e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ICNLOFLE_02143 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ICNLOFLE_02144 1.6e-32
ICNLOFLE_02145 2.5e-83 6.3.3.2 S ASCH
ICNLOFLE_02146 7.1e-62
ICNLOFLE_02147 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
ICNLOFLE_02148 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICNLOFLE_02149 3.7e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICNLOFLE_02150 1.2e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
ICNLOFLE_02151 1.4e-152 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
ICNLOFLE_02152 6.9e-192
ICNLOFLE_02153 7.8e-131
ICNLOFLE_02154 1.6e-293
ICNLOFLE_02156 6.7e-276 2.4.1.9, 3.4.24.40 GH68 S peptidase inhibitor activity
ICNLOFLE_02157 2.8e-41 tnp2PF3 L Transposase DDE domain
ICNLOFLE_02158 1.2e-79 K Putative DNA-binding domain
ICNLOFLE_02159 1.5e-09
ICNLOFLE_02160 2.4e-63 S Phage derived protein Gp49-like (DUF891)
ICNLOFLE_02161 5.2e-41 K Helix-turn-helix domain
ICNLOFLE_02162 1.4e-18 V Type II restriction enzyme, methylase subunits
ICNLOFLE_02163 1.1e-124 tnp L DDE domain
ICNLOFLE_02164 1.7e-84 dps P Belongs to the Dps family
ICNLOFLE_02165 9.1e-133 V AAA domain, putative AbiEii toxin, Type IV TA system
ICNLOFLE_02166 3.4e-164 V ABC-type multidrug transport system, permease component
ICNLOFLE_02167 4.1e-116 K Bacterial regulatory proteins, tetR family
ICNLOFLE_02168 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
ICNLOFLE_02169 4.6e-32 copZ P Heavy-metal-associated domain
ICNLOFLE_02170 1.2e-97 dps P Belongs to the Dps family
ICNLOFLE_02171 1.3e-38 repA S Replication initiator protein A
ICNLOFLE_02172 2.4e-47
ICNLOFLE_02173 9.4e-58
ICNLOFLE_02174 5.6e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICNLOFLE_02175 1.5e-116 ydfK S Protein of unknown function (DUF554)
ICNLOFLE_02176 5.1e-89
ICNLOFLE_02180 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_02181 2.8e-171 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
ICNLOFLE_02182 1.1e-130 rpl K Helix-turn-helix domain, rpiR family
ICNLOFLE_02183 1.1e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICNLOFLE_02184 1.7e-43 trxC O Belongs to the thioredoxin family
ICNLOFLE_02185 6.6e-134 thrE S Putative threonine/serine exporter
ICNLOFLE_02186 3.5e-74 S Threonine/Serine exporter, ThrE
ICNLOFLE_02187 4.4e-214 livJ E Receptor family ligand binding region
ICNLOFLE_02188 6.7e-151 livH U Branched-chain amino acid transport system / permease component
ICNLOFLE_02189 1.7e-120 livM E Branched-chain amino acid transport system / permease component
ICNLOFLE_02190 2.1e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
ICNLOFLE_02191 1.1e-124 livF E ABC transporter
ICNLOFLE_02192 3.7e-54 yvdC S MazG nucleotide pyrophosphohydrolase domain
ICNLOFLE_02193 1.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
ICNLOFLE_02194 1.1e-184 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICNLOFLE_02195 6.2e-42 L Transposase DDE domain
ICNLOFLE_02196 1.3e-38 repA S Replication initiator protein A
ICNLOFLE_02197 7.1e-43
ICNLOFLE_02198 0.0 pacL 3.6.3.8 P P-type ATPase
ICNLOFLE_02199 5.2e-127 tnp L DDE domain
ICNLOFLE_02200 3.4e-195 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ICNLOFLE_02201 4.3e-80 tnp2PF3 L Transposase DDE domain
ICNLOFLE_02202 3.2e-33 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICNLOFLE_02203 1.2e-113 3.1.21.3 V Type I restriction
ICNLOFLE_02204 1.1e-15
ICNLOFLE_02205 2.8e-171 L Transposase
ICNLOFLE_02206 2.1e-182 yveB 2.7.4.29 I PAP2 superfamily
ICNLOFLE_02207 5.8e-213 mccF V LD-carboxypeptidase
ICNLOFLE_02208 2.5e-42
ICNLOFLE_02209 1.1e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ICNLOFLE_02210 1.1e-40
ICNLOFLE_02211 1e-111
ICNLOFLE_02212 3.4e-226 EGP Major facilitator Superfamily
ICNLOFLE_02213 7.7e-15 msmX P Belongs to the ABC transporter superfamily
ICNLOFLE_02214 2e-115 L Resolvase, N terminal domain
ICNLOFLE_02215 3.2e-46 ligA 6.5.1.2 L BRCA1 C Terminus (BRCT) domain
ICNLOFLE_02216 3.2e-40 L Transposase and inactivated derivatives
ICNLOFLE_02217 6.4e-137 L Integrase core domain
ICNLOFLE_02218 2.3e-51 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
ICNLOFLE_02219 3e-286 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
ICNLOFLE_02220 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
ICNLOFLE_02221 3e-151 lacT K PRD domain
ICNLOFLE_02222 4.2e-50 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
ICNLOFLE_02223 1.8e-33 tnp2PF3 L Transposase DDE domain
ICNLOFLE_02224 4e-42 tnp2PF3 L Transposase DDE domain
ICNLOFLE_02225 1.7e-46 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICNLOFLE_02226 7.7e-55 tnp2PF3 L Transposase DDE domain
ICNLOFLE_02227 8.1e-42 L Transposase DDE domain
ICNLOFLE_02229 5.7e-222 M Glycosyl hydrolases family 25
ICNLOFLE_02230 5e-78 M Glycosyl hydrolases family 25
ICNLOFLE_02231 5.2e-164 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ICNLOFLE_02232 1.7e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
ICNLOFLE_02233 3.9e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ICNLOFLE_02234 5.2e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ICNLOFLE_02235 1.9e-92
ICNLOFLE_02236 1.4e-240
ICNLOFLE_02237 2.5e-56
ICNLOFLE_02238 7.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ICNLOFLE_02239 9.5e-49
ICNLOFLE_02240 5.8e-274 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
ICNLOFLE_02241 1.3e-298 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
ICNLOFLE_02243 2.3e-131 K Helix-turn-helix domain, rpiR family
ICNLOFLE_02244 1.9e-83 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
ICNLOFLE_02246 2.8e-41 tnp2PF3 L Transposase DDE domain
ICNLOFLE_02247 9.5e-55 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
ICNLOFLE_02248 9.9e-126 tnp L DDE domain
ICNLOFLE_02250 1.7e-101 D CobQ CobB MinD ParA nucleotide binding domain protein
ICNLOFLE_02251 2.3e-95 repE K Primase C terminal 1 (PriCT-1)
ICNLOFLE_02252 4.6e-118
ICNLOFLE_02253 2.2e-123
ICNLOFLE_02254 1.1e-118 V ATPases associated with a variety of cellular activities
ICNLOFLE_02255 4.8e-79
ICNLOFLE_02256 7.8e-82 S NUDIX domain
ICNLOFLE_02257 1.1e-133 mod 2.1.1.72, 3.1.21.5 L DNA methylase
ICNLOFLE_02258 3e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICNLOFLE_02259 2.9e-193 yegS 2.7.1.107 G Lipid kinase
ICNLOFLE_02260 1.8e-278 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICNLOFLE_02261 1.3e-263 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ICNLOFLE_02262 9.2e-44 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICNLOFLE_02263 2e-203 camS S sex pheromone
ICNLOFLE_02264 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICNLOFLE_02265 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
ICNLOFLE_02266 4.7e-46 yjgN S Bacterial protein of unknown function (DUF898)
ICNLOFLE_02267 2.6e-106 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
ICNLOFLE_02268 2.6e-174 S response to antibiotic
ICNLOFLE_02270 1.6e-249 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
ICNLOFLE_02271 5.3e-59
ICNLOFLE_02272 3.8e-82
ICNLOFLE_02273 5.2e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
ICNLOFLE_02274 7.6e-31
ICNLOFLE_02275 9.5e-92 yhbS S acetyltransferase
ICNLOFLE_02276 7.1e-273 yclK 2.7.13.3 T Histidine kinase
ICNLOFLE_02277 3.1e-133 K response regulator
ICNLOFLE_02278 1.7e-69 S SdpI/YhfL protein family
ICNLOFLE_02280 0.0 rafA 3.2.1.22 G alpha-galactosidase
ICNLOFLE_02281 1.1e-166 arbZ I Phosphate acyltransferases
ICNLOFLE_02282 2.6e-180 arbY M family 8
ICNLOFLE_02283 3.3e-163 arbx M Glycosyl transferase family 8
ICNLOFLE_02284 1.2e-143 arbV 2.3.1.51 I Phosphate acyltransferases
ICNLOFLE_02285 1.2e-247 cycA E Amino acid permease
ICNLOFLE_02286 3.8e-73
ICNLOFLE_02287 8.2e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
ICNLOFLE_02288 3.7e-46
ICNLOFLE_02289 6.4e-76
ICNLOFLE_02290 7.9e-52
ICNLOFLE_02292 5.1e-48
ICNLOFLE_02293 6.8e-165 comGB NU type II secretion system
ICNLOFLE_02294 2.1e-133 comGA NU Type II IV secretion system protein
ICNLOFLE_02295 3.4e-132 yebC K Transcriptional regulatory protein
ICNLOFLE_02296 9.7e-91 S VanZ like family
ICNLOFLE_02297 0.0 pepF2 E Oligopeptidase F
ICNLOFLE_02298 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ICNLOFLE_02299 2.6e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICNLOFLE_02300 5.4e-166 ybbR S YbbR-like protein
ICNLOFLE_02301 1e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ICNLOFLE_02302 3.9e-128 V AAA domain, putative AbiEii toxin, Type IV TA system
ICNLOFLE_02303 4.9e-186 V ABC transporter
ICNLOFLE_02304 2.9e-117 K Transcriptional regulator
ICNLOFLE_02305 6.6e-82 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
ICNLOFLE_02306 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
ICNLOFLE_02308 6.8e-14 T SpoVT / AbrB like domain
ICNLOFLE_02309 1.6e-207 potD P ABC transporter
ICNLOFLE_02310 8.9e-145 potC P ABC transporter permease
ICNLOFLE_02311 1.7e-148 potB P ABC transporter permease
ICNLOFLE_02312 1.7e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
ICNLOFLE_02313 2.9e-96 puuR K Cupin domain
ICNLOFLE_02314 0.0 yjcE P Sodium proton antiporter
ICNLOFLE_02315 9.8e-166 murB 1.3.1.98 M Cell wall formation
ICNLOFLE_02316 3.2e-149 xth 3.1.11.2 L exodeoxyribonuclease III
ICNLOFLE_02317 3.1e-98 dnaQ 2.7.7.7 L DNA polymerase III
ICNLOFLE_02318 1.7e-219 ysdA CP ABC-2 family transporter protein
ICNLOFLE_02319 1.5e-166 natA S ABC transporter, ATP-binding protein
ICNLOFLE_02320 3.2e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
ICNLOFLE_02321 6.5e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
ICNLOFLE_02322 4.6e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICNLOFLE_02323 2e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
ICNLOFLE_02324 9e-92 yxjI
ICNLOFLE_02325 4.4e-103 3.2.2.20 K Acetyltransferase (GNAT) domain
ICNLOFLE_02326 1.6e-194 malK P ATPases associated with a variety of cellular activities
ICNLOFLE_02327 2.6e-166 malG P ABC-type sugar transport systems, permease components
ICNLOFLE_02328 1.9e-147 malF G Binding-protein-dependent transport system inner membrane component
ICNLOFLE_02329 4.4e-239 malE G Bacterial extracellular solute-binding protein
ICNLOFLE_02330 1.2e-238 YSH1 S Metallo-beta-lactamase superfamily
ICNLOFLE_02331 8.7e-50
ICNLOFLE_02332 1.2e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
ICNLOFLE_02333 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
ICNLOFLE_02334 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
ICNLOFLE_02335 3.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ICNLOFLE_02336 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ICNLOFLE_02337 1.2e-137 est 3.1.1.1 S Serine aminopeptidase, S33
ICNLOFLE_02338 9.3e-31 secG U Preprotein translocase
ICNLOFLE_02339 1.7e-60
ICNLOFLE_02340 3.7e-293 clcA P chloride
ICNLOFLE_02341 5.9e-64
ICNLOFLE_02342 3.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ICNLOFLE_02343 1.7e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICNLOFLE_02344 1.5e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
ICNLOFLE_02345 2.2e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ICNLOFLE_02346 3.6e-188 cggR K Putative sugar-binding domain
ICNLOFLE_02348 2.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ICNLOFLE_02349 5.5e-80 ohrR K helix_turn_helix multiple antibiotic resistance protein
ICNLOFLE_02350 1.6e-171 whiA K May be required for sporulation
ICNLOFLE_02351 7.7e-191 ybhK S Required for morphogenesis under gluconeogenic growth conditions
ICNLOFLE_02352 1.3e-165 rapZ S Displays ATPase and GTPase activities
ICNLOFLE_02353 5e-80 S Short repeat of unknown function (DUF308)
ICNLOFLE_02354 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ICNLOFLE_02355 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ICNLOFLE_02356 4.7e-117 yfbR S HD containing hydrolase-like enzyme
ICNLOFLE_02357 2.1e-247 V FtsX-like permease family
ICNLOFLE_02358 1.5e-91 V ABC transporter
ICNLOFLE_02359 1.2e-114 T His Kinase A (phosphoacceptor) domain
ICNLOFLE_02360 1.5e-83 T Transcriptional regulatory protein, C terminal
ICNLOFLE_02361 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
ICNLOFLE_02362 1.5e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ICNLOFLE_02363 1.8e-195 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
ICNLOFLE_02364 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICNLOFLE_02365 2.8e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ICNLOFLE_02366 1.3e-46 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
ICNLOFLE_02367 2.1e-31
ICNLOFLE_02368 7.5e-211 yvlB S Putative adhesin
ICNLOFLE_02369 1e-169 L Transposase DDE domain
ICNLOFLE_02370 1e-119 phoU P Plays a role in the regulation of phosphate uptake
ICNLOFLE_02371 7.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICNLOFLE_02372 4.5e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICNLOFLE_02373 1.1e-156 pstA P Phosphate transport system permease protein PstA
ICNLOFLE_02374 3.4e-161 pstC P probably responsible for the translocation of the substrate across the membrane
ICNLOFLE_02375 5.2e-156 pstS P Phosphate
ICNLOFLE_02376 1.2e-305 phoR 2.7.13.3 T Histidine kinase
ICNLOFLE_02377 3.4e-129 K response regulator
ICNLOFLE_02378 2.5e-195 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
ICNLOFLE_02379 1.8e-159 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
ICNLOFLE_02380 1.9e-124 ftsE D ABC transporter
ICNLOFLE_02381 8.9e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ICNLOFLE_02382 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ICNLOFLE_02383 4.7e-10
ICNLOFLE_02384 5.4e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICNLOFLE_02385 1.8e-89 comFC S Competence protein
ICNLOFLE_02386 1.4e-234 comFA L Helicase C-terminal domain protein
ICNLOFLE_02387 2.1e-117 yvyE 3.4.13.9 S YigZ family
ICNLOFLE_02388 1.7e-242 rny S Endoribonuclease that initiates mRNA decay
ICNLOFLE_02389 2.3e-26
ICNLOFLE_02390 1.9e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICNLOFLE_02391 3.1e-226 cinA 3.5.1.42 S Belongs to the CinA family
ICNLOFLE_02392 1.6e-103 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICNLOFLE_02393 5.7e-116 ymfM S Helix-turn-helix domain
ICNLOFLE_02394 1.7e-128 IQ Enoyl-(Acyl carrier protein) reductase
ICNLOFLE_02395 8.9e-245 ymfH S Peptidase M16
ICNLOFLE_02396 1.1e-228 ymfF S Peptidase M16 inactive domain protein
ICNLOFLE_02397 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
ICNLOFLE_02398 6.2e-42 L Transposase DDE domain
ICNLOFLE_02399 9.4e-27
ICNLOFLE_02402 2.1e-152 K Bacteriophage CI repressor helix-turn-helix domain
ICNLOFLE_02404 0.0 cadA P P-type ATPase
ICNLOFLE_02405 1.4e-68 V Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
ICNLOFLE_02406 6e-163 V ABC transporter
ICNLOFLE_02407 9.6e-89 S CAAX protease self-immunity
ICNLOFLE_02408 1.7e-11 V Beta-lactamase enzyme family
ICNLOFLE_02409 5.1e-54 S Bacterial mobilisation protein (MobC)
ICNLOFLE_02410 2.4e-42 S Relaxase/Mobilisation nuclease domain
ICNLOFLE_02411 2.5e-30
ICNLOFLE_02413 4.5e-63
ICNLOFLE_02414 8.5e-19 rom S Rop protein
ICNLOFLE_02416 4.9e-56 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ICNLOFLE_02417 7.5e-07 S Domain of unknown function (DUF932)
ICNLOFLE_02418 1.9e-146 S Phage tail sheath C-terminal domain
ICNLOFLE_02419 6.1e-88 L Helix-turn-helix domain
ICNLOFLE_02420 6.4e-34 L Helix-turn-helix domain
ICNLOFLE_02421 6.3e-215 lsgC M Glycosyl transferases group 1
ICNLOFLE_02422 0.0 yebA E Transglutaminase/protease-like homologues
ICNLOFLE_02423 1.2e-158 yeaD S Protein of unknown function DUF58
ICNLOFLE_02424 1.5e-169 yeaC S ATPase family associated with various cellular activities (AAA)
ICNLOFLE_02425 6.7e-105 S Stage II sporulation protein M
ICNLOFLE_02426 4e-101 ydaF J Acetyltransferase (GNAT) domain
ICNLOFLE_02427 4.7e-266 glnP P ABC transporter
ICNLOFLE_02428 6.5e-257 glnP P ABC transporter
ICNLOFLE_02429 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ICNLOFLE_02430 2.4e-169 yniA G Phosphotransferase enzyme family
ICNLOFLE_02431 3.7e-145 S AAA ATPase domain
ICNLOFLE_02432 1.3e-287 ydbT S Bacterial PH domain
ICNLOFLE_02433 8.7e-81 S Bacterial PH domain
ICNLOFLE_02434 1.2e-52
ICNLOFLE_02435 1.5e-58 yqkB S Iron-sulphur cluster biosynthesis
ICNLOFLE_02436 5.1e-133 S Protein of unknown function (DUF975)
ICNLOFLE_02437 5.6e-239 malE G Bacterial extracellular solute-binding protein
ICNLOFLE_02438 2e-40
ICNLOFLE_02439 2.4e-133 glnQ E ABC transporter, ATP-binding protein
ICNLOFLE_02440 4e-287 glnP P ABC transporter permease
ICNLOFLE_02442 1e-68 ybfG M peptidoglycan-binding domain-containing protein
ICNLOFLE_02443 0.0 ybfG M peptidoglycan-binding domain-containing protein
ICNLOFLE_02448 7.8e-160 K sequence-specific DNA binding
ICNLOFLE_02449 1.4e-150 K Helix-turn-helix XRE-family like proteins
ICNLOFLE_02450 1e-190 K Helix-turn-helix XRE-family like proteins
ICNLOFLE_02451 1.8e-221 EGP Major facilitator Superfamily
ICNLOFLE_02452 1.3e-182 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
ICNLOFLE_02453 1.6e-122 manY G PTS system
ICNLOFLE_02454 8.7e-170 manN G system, mannose fructose sorbose family IID component
ICNLOFLE_02455 4.4e-64 manO S Domain of unknown function (DUF956)
ICNLOFLE_02456 2.9e-173 iolS C Aldo keto reductase
ICNLOFLE_02457 2.9e-213 yeaN P Transporter, major facilitator family protein
ICNLOFLE_02458 4.1e-259 ydiC1 EGP Major Facilitator Superfamily
ICNLOFLE_02459 6.7e-113 ycaC Q Isochorismatase family
ICNLOFLE_02460 1e-90 S AAA domain
ICNLOFLE_02461 1e-83 F NUDIX domain
ICNLOFLE_02462 4.4e-108 speG J Acetyltransferase (GNAT) domain
ICNLOFLE_02463 4.9e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
ICNLOFLE_02464 1.3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_02465 6.9e-130 K UbiC transcription regulator-associated domain protein
ICNLOFLE_02466 2e-239 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICNLOFLE_02467 1.2e-73 S Domain of unknown function (DUF3284)
ICNLOFLE_02468 2.2e-215 S Bacterial protein of unknown function (DUF871)
ICNLOFLE_02469 4.8e-268 argH 4.3.2.1 E argininosuccinate lyase
ICNLOFLE_02470 1e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
ICNLOFLE_02471 9.3e-259 arpJ P ABC transporter permease
ICNLOFLE_02472 1.8e-124 S Alpha/beta hydrolase family
ICNLOFLE_02473 8.1e-131 K response regulator
ICNLOFLE_02474 0.0 vicK 2.7.13.3 T Histidine kinase
ICNLOFLE_02475 1.3e-260 yycH S YycH protein
ICNLOFLE_02476 1.1e-141 yycI S YycH protein
ICNLOFLE_02477 2.7e-154 vicX 3.1.26.11 S domain protein
ICNLOFLE_02478 2e-10
ICNLOFLE_02479 6.3e-201 htrA 3.4.21.107 O serine protease
ICNLOFLE_02480 5.9e-70 S Iron-sulphur cluster biosynthesis
ICNLOFLE_02481 2.7e-76 hsp3 O Hsp20/alpha crystallin family
ICNLOFLE_02482 0.0 cadA P P-type ATPase
ICNLOFLE_02483 6.6e-133
ICNLOFLE_02484 8.8e-215 E ABC transporter, substratebinding protein
ICNLOFLE_02485 8.1e-73 E ABC transporter, substratebinding protein
ICNLOFLE_02486 7e-253 E Peptidase dimerisation domain
ICNLOFLE_02487 9.6e-102
ICNLOFLE_02488 4.1e-198 ybiR P Citrate transporter
ICNLOFLE_02489 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICNLOFLE_02490 4.7e-68 6.3.3.2 S ASCH
ICNLOFLE_02491 3.1e-124
ICNLOFLE_02492 3.8e-84 K Acetyltransferase (GNAT) domain
ICNLOFLE_02493 5.9e-132 wzb 3.1.3.48 T Tyrosine phosphatase family
ICNLOFLE_02494 2.8e-90 MA20_25245 K FR47-like protein
ICNLOFLE_02495 2.4e-110 S alpha beta
ICNLOFLE_02496 1.2e-36
ICNLOFLE_02497 3.1e-61
ICNLOFLE_02500 1.7e-51 sugE U Multidrug resistance protein
ICNLOFLE_02501 1e-173 draG 3.2.2.24 O ADP-ribosylglycohydrolase
ICNLOFLE_02502 6.1e-145 Q Methyltransferase
ICNLOFLE_02503 1.3e-75 adhR K helix_turn_helix, mercury resistance
ICNLOFLE_02504 4.5e-160 1.1.1.346 S reductase
ICNLOFLE_02505 2e-174 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
ICNLOFLE_02506 2.4e-203 S endonuclease exonuclease phosphatase family protein
ICNLOFLE_02508 3.3e-131 G PTS system sorbose-specific iic component
ICNLOFLE_02509 4.9e-151 G PTS system mannose/fructose/sorbose family IID component
ICNLOFLE_02510 1.5e-80 2.7.1.191 G PTS system sorbose subfamily IIB component
ICNLOFLE_02511 6.7e-165 ybbH_2 K Helix-turn-helix domain, rpiR family
ICNLOFLE_02512 7.4e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ICNLOFLE_02513 1.7e-198 blaA6 V Beta-lactamase
ICNLOFLE_02514 8.6e-150 3.5.2.6 V Beta-lactamase enzyme family
ICNLOFLE_02515 3.2e-226 EGP Major facilitator Superfamily
ICNLOFLE_02516 2.5e-211 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
ICNLOFLE_02517 6.6e-165 ugpA P ABC-type sugar transport systems, permease components
ICNLOFLE_02518 2.2e-148 ugpE G ABC transporter permease
ICNLOFLE_02519 2.9e-241 ugpB G Bacterial extracellular solute-binding protein
ICNLOFLE_02520 9.3e-71 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICNLOFLE_02521 3.2e-132 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ICNLOFLE_02522 1.1e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICNLOFLE_02523 4.5e-108 pncA Q Isochorismatase family
ICNLOFLE_02524 1.5e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
ICNLOFLE_02525 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
ICNLOFLE_02526 4.4e-143 sca1 G Belongs to the glycosyl hydrolase 31 family
ICNLOFLE_02527 8.6e-99 K Helix-turn-helix domain
ICNLOFLE_02529 1.4e-113 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
ICNLOFLE_02530 3.1e-92 yjgM K Acetyltransferase (GNAT) domain
ICNLOFLE_02531 2.4e-133 farR K Helix-turn-helix domain
ICNLOFLE_02532 6.9e-161 gatY G Fructose-bisphosphate aldolase class-II
ICNLOFLE_02533 9.9e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_02534 1.6e-48 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_02535 4.7e-252 gatC G PTS system sugar-specific permease component
ICNLOFLE_02536 2.2e-279 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
ICNLOFLE_02537 3.7e-162 G Fructose-bisphosphate aldolase class-II
ICNLOFLE_02538 5.3e-246 licR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_02539 1.9e-68 ahaA 2.7.1.191 G PTS system fructose IIA component
ICNLOFLE_02540 2.4e-89 K ECF sigma factor
ICNLOFLE_02541 2.5e-67 L Protein of unknown function (DUF2800)
ICNLOFLE_02542 8.1e-42 L Transposase DDE domain
ICNLOFLE_02543 4.7e-48 tnp2PF3 L Transposase DDE domain
ICNLOFLE_02544 7.2e-77 L Protein of unknown function (DUF2800)
ICNLOFLE_02546 1.4e-22
ICNLOFLE_02547 8.8e-87 L Helix-turn-helix domain
ICNLOFLE_02549 7.6e-18 S tail protein
ICNLOFLE_02551 1.3e-85
ICNLOFLE_02552 8.7e-92 S MucBP domain
ICNLOFLE_02553 2.9e-119 ywnB S NAD(P)H-binding
ICNLOFLE_02556 3.5e-88 E AAA domain
ICNLOFLE_02557 1.9e-122 E lipolytic protein G-D-S-L family
ICNLOFLE_02558 3.2e-101 feoA P FeoA
ICNLOFLE_02559 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
ICNLOFLE_02560 1.6e-24 S Virus attachment protein p12 family
ICNLOFLE_02561 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
ICNLOFLE_02562 1e-56
ICNLOFLE_02563 3.7e-234 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
ICNLOFLE_02564 1.6e-263 G MFS/sugar transport protein
ICNLOFLE_02565 5.4e-74 S function, without similarity to other proteins
ICNLOFLE_02566 1.4e-65
ICNLOFLE_02567 0.0 macB_3 V ABC transporter, ATP-binding protein
ICNLOFLE_02568 3e-257 dtpT U amino acid peptide transporter
ICNLOFLE_02569 7.5e-160 yjjH S Calcineurin-like phosphoesterase
ICNLOFLE_02571 2.1e-282 mga K Mga helix-turn-helix domain
ICNLOFLE_02572 0.0 sprD D Domain of Unknown Function (DUF1542)
ICNLOFLE_02573 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
ICNLOFLE_02574 7.7e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICNLOFLE_02575 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICNLOFLE_02576 6.6e-125 gntR1 K UbiC transcription regulator-associated domain protein
ICNLOFLE_02577 2.3e-281 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICNLOFLE_02578 6.8e-223 V Beta-lactamase
ICNLOFLE_02579 1.3e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ICNLOFLE_02580 2.4e-217 V Beta-lactamase
ICNLOFLE_02581 0.0 pacL 3.6.3.8 P P-type ATPase
ICNLOFLE_02582 1.3e-73
ICNLOFLE_02583 2.3e-176 XK27_08835 S ABC transporter
ICNLOFLE_02584 1.1e-129 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
ICNLOFLE_02585 5e-131 XK27_08845 S ABC transporter, ATP-binding protein
ICNLOFLE_02586 6.2e-84 ydcK S Belongs to the SprT family
ICNLOFLE_02587 1.9e-80 yodP 2.3.1.264 K FR47-like protein
ICNLOFLE_02589 1.5e-101 S ECF transporter, substrate-specific component
ICNLOFLE_02590 1e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ICNLOFLE_02591 4.1e-158 5.1.3.3 G Aldose 1-epimerase
ICNLOFLE_02592 1.8e-101 V Restriction endonuclease
ICNLOFLE_02593 3e-161 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
ICNLOFLE_02594 3.3e-49
ICNLOFLE_02595 5e-210 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
ICNLOFLE_02596 9.7e-212 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
ICNLOFLE_02597 1.5e-219 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
ICNLOFLE_02598 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
ICNLOFLE_02599 9.8e-80 F Nucleoside 2-deoxyribosyltransferase
ICNLOFLE_02600 5.7e-250 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICNLOFLE_02601 6e-64
ICNLOFLE_02602 9.7e-291 frvR K Mga helix-turn-helix domain
ICNLOFLE_02603 1.4e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
ICNLOFLE_02604 1.4e-104 ygaC J Belongs to the UPF0374 family
ICNLOFLE_02605 1.2e-96
ICNLOFLE_02606 8.6e-75 S Acetyltransferase (GNAT) domain
ICNLOFLE_02607 6.8e-207 yueF S AI-2E family transporter
ICNLOFLE_02608 2.5e-242 hlyX S Transporter associated domain
ICNLOFLE_02609 3.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ICNLOFLE_02610 4.3e-46 XK27_09445 S Domain of unknown function (DUF1827)
ICNLOFLE_02611 0.0 clpE O Belongs to the ClpA ClpB family
ICNLOFLE_02612 2e-28
ICNLOFLE_02613 2.7e-39 ptsH G phosphocarrier protein HPR
ICNLOFLE_02614 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICNLOFLE_02615 1.8e-254 iolT EGP Major facilitator Superfamily
ICNLOFLE_02616 2.7e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
ICNLOFLE_02617 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ICNLOFLE_02618 3.6e-210 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ICNLOFLE_02619 2.3e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
ICNLOFLE_02620 6.4e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICNLOFLE_02621 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICNLOFLE_02622 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICNLOFLE_02623 6.9e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ICNLOFLE_02624 6.9e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
ICNLOFLE_02625 7.8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICNLOFLE_02626 1.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
ICNLOFLE_02627 2.6e-217 purD 6.3.4.13 F Belongs to the GARS family
ICNLOFLE_02628 2.5e-77 copR K Copper transport repressor CopY TcrY
ICNLOFLE_02629 0.0 copB 3.6.3.4 P P-type ATPase
ICNLOFLE_02630 3.2e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ICNLOFLE_02631 9.8e-208 T PhoQ Sensor
ICNLOFLE_02632 1e-122 K response regulator
ICNLOFLE_02633 7.4e-138 bceA V ABC transporter
ICNLOFLE_02634 0.0 V ABC transporter (permease)
ICNLOFLE_02635 7.6e-91 traP 1.14.99.57, 6.2.1.3 S Antibiotic biosynthesis monooxygenase
ICNLOFLE_02636 1.9e-138 yhfI S Metallo-beta-lactamase superfamily
ICNLOFLE_02637 1.5e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ICNLOFLE_02638 5.1e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
ICNLOFLE_02639 4.1e-304 glpQ 3.1.4.46 C phosphodiesterase
ICNLOFLE_02640 1.2e-177 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
ICNLOFLE_02641 2.9e-16
ICNLOFLE_02642 1.2e-67
ICNLOFLE_02644 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ICNLOFLE_02645 1.5e-74 argR K Regulates arginine biosynthesis genes
ICNLOFLE_02646 2.9e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICNLOFLE_02647 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ICNLOFLE_02648 4.6e-55 yheA S Control of competence regulator ComK, YlbF/YmcA
ICNLOFLE_02649 8.1e-25 L Uncharacterised protein family (UPF0236)
ICNLOFLE_02650 2.7e-271 L Uncharacterised protein family (UPF0236)
ICNLOFLE_02651 1.6e-89 S Phage terminase large subunit (GpA)
ICNLOFLE_02652 2.1e-32 JD73_18735 F Phage portal protein, lambda family
ICNLOFLE_02655 4.6e-82 tnp2PF3 L Transposase DDE domain
ICNLOFLE_02656 3.3e-37 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_02657 3.7e-58 gntR K rpiR family
ICNLOFLE_02658 9.2e-56 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
ICNLOFLE_02659 5.9e-63 K DeoR C terminal sensor domain
ICNLOFLE_02660 4.1e-30 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_02661 8.1e-09 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_02662 4.8e-188 pts36C G iic component
ICNLOFLE_02664 2.9e-97 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
ICNLOFLE_02665 2.2e-250 frdC 1.3.5.4 C HI0933-like protein
ICNLOFLE_02666 4.3e-292 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
ICNLOFLE_02667 4.7e-244 G Major Facilitator
ICNLOFLE_02668 1.3e-150 K Transcriptional regulator, LacI family
ICNLOFLE_02669 2.1e-146 cbiQ P cobalt transport
ICNLOFLE_02670 0.0 3.6.3.24 P ATP-binding cassette cobalt transporter
ICNLOFLE_02671 3.5e-97 S UPF0397 protein
ICNLOFLE_02672 1.1e-158 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
ICNLOFLE_02673 4.9e-149 4.1.2.13 G Fructose-bisphosphate aldolase class-II
ICNLOFLE_02674 1.2e-149 sorM G system, mannose fructose sorbose family IID component
ICNLOFLE_02675 7.3e-131 sorA U PTS system sorbose-specific iic component
ICNLOFLE_02676 6.6e-79 sorB 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
ICNLOFLE_02677 3.6e-62 sorF 2.7.1.191, 2.7.1.206 G PTS system fructose IIA component
ICNLOFLE_02678 4.1e-131 IQ NAD dependent epimerase/dehydratase family
ICNLOFLE_02679 2.2e-163 sorC K sugar-binding domain protein
ICNLOFLE_02680 5.4e-239 sorE E Alcohol dehydrogenase GroES-like domain
ICNLOFLE_02681 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphotransferase system
ICNLOFLE_02682 6.4e-154 4.1.2.13 G Fructose-bisphosphate aldolase class-II
ICNLOFLE_02683 1e-286 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_02684 2e-139 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
ICNLOFLE_02685 8.5e-126 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
ICNLOFLE_02686 1.8e-91 IQ KR domain
ICNLOFLE_02687 1.4e-180 2.7.1.53 G Belongs to the FGGY kinase family
ICNLOFLE_02688 1.4e-37 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ICNLOFLE_02689 1.7e-89 4.1.2.13 G DeoC/LacD family aldolase
ICNLOFLE_02690 1.4e-117 K helix_turn_helix gluconate operon transcriptional repressor
ICNLOFLE_02691 5.3e-44 K Acetyltransferase (GNAT) family
ICNLOFLE_02692 4.9e-212 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
ICNLOFLE_02693 7.3e-156 rihB 3.2.2.1 F Nucleoside
ICNLOFLE_02694 4.9e-87 6.3.4.4 S Zeta toxin
ICNLOFLE_02695 1.2e-149 4.1.2.13 G Fructose-bisphosphate aldolase class-II
ICNLOFLE_02696 5.1e-48
ICNLOFLE_02697 1.4e-205 ulaA 2.7.1.194 S PTS system sugar-specific permease component
ICNLOFLE_02698 2.1e-46 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_02699 1e-165 GKT transcriptional antiterminator
ICNLOFLE_02700 4.7e-36 K Helix-turn-helix XRE-family like proteins
ICNLOFLE_02701 3.5e-29
ICNLOFLE_02702 1.5e-103
ICNLOFLE_02703 2.1e-68 K helix_turn_helix multiple antibiotic resistance protein
ICNLOFLE_02704 3e-238 ydiC1 EGP Major facilitator Superfamily
ICNLOFLE_02705 1.8e-91
ICNLOFLE_02706 4.2e-60
ICNLOFLE_02707 6.2e-78
ICNLOFLE_02708 6.4e-87 V AAA domain, putative AbiEii toxin, Type IV TA system
ICNLOFLE_02709 5e-53
ICNLOFLE_02710 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
ICNLOFLE_02711 2e-38 K DNA-binding helix-turn-helix protein
ICNLOFLE_02712 9.6e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICNLOFLE_02713 8e-158 rbsB G Periplasmic binding protein domain
ICNLOFLE_02714 1e-152 rbsC U Belongs to the binding-protein-dependent transport system permease family
ICNLOFLE_02715 1.7e-269 rbsA 3.6.3.17 G ABC transporter
ICNLOFLE_02716 8.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ICNLOFLE_02717 2.6e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
ICNLOFLE_02718 1.5e-272 E Amino acid permease
ICNLOFLE_02719 2.7e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICNLOFLE_02720 1.4e-102 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ICNLOFLE_02721 6e-149 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ICNLOFLE_02722 1.9e-81 thiW S Thiamine-precursor transporter protein (ThiW)
ICNLOFLE_02723 4.5e-126 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ICNLOFLE_02724 6.5e-111 P cobalt transport
ICNLOFLE_02725 1.3e-243 P ABC transporter
ICNLOFLE_02726 8.3e-94 S ABC-type cobalt transport system, permease component
ICNLOFLE_02727 3.4e-170 nisT V ABC transporter
ICNLOFLE_02728 3e-125 nisT V ABC transporter
ICNLOFLE_02730 4.5e-120 S Acetyltransferase (GNAT) family
ICNLOFLE_02731 3.2e-292 E ABC transporter, substratebinding protein
ICNLOFLE_02732 2.3e-237 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
ICNLOFLE_02733 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ICNLOFLE_02734 9.2e-192 ypdE E M42 glutamyl aminopeptidase
ICNLOFLE_02735 3.8e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
ICNLOFLE_02736 1.8e-59 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
ICNLOFLE_02737 3.1e-253 2.7.1.207 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICNLOFLE_02738 4.1e-203 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ICNLOFLE_02739 1.5e-233 4.4.1.8 E Aminotransferase, class I
ICNLOFLE_02740 2.2e-219 S Uncharacterized protein conserved in bacteria (DUF2325)
ICNLOFLE_02741 0.0 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
ICNLOFLE_02742 3.4e-241 2.4.1.52 GT4 M Glycosyl transferases group 1
ICNLOFLE_02743 6.2e-42 L Transposase DDE domain
ICNLOFLE_02744 6.1e-35
ICNLOFLE_02745 2.6e-140 ksgA 2.1.1.182, 2.1.1.197, 2.5.1.134 J rRNA (adenine-N6,N6-)-dimethyltransferase activity
ICNLOFLE_02746 1.5e-294 S ABC transporter
ICNLOFLE_02747 1.4e-175 draG O ADP-ribosylglycohydrolase
ICNLOFLE_02748 2e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
ICNLOFLE_02749 2.6e-53
ICNLOFLE_02750 4.8e-134 XK27_06755 S Protein of unknown function (DUF975)
ICNLOFLE_02751 8.9e-147 M Glycosyltransferase like family 2
ICNLOFLE_02752 2.2e-134 glcR K DeoR C terminal sensor domain
ICNLOFLE_02753 7.4e-73 T Sh3 type 3 domain protein
ICNLOFLE_02754 2.3e-246 brnQ U Component of the transport system for branched-chain amino acids
ICNLOFLE_02755 2e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ICNLOFLE_02756 0.0 pepF E oligoendopeptidase F
ICNLOFLE_02757 5.8e-163 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
ICNLOFLE_02758 3.8e-167 T Calcineurin-like phosphoesterase superfamily domain
ICNLOFLE_02759 3e-134 znuB U ABC 3 transport family
ICNLOFLE_02760 4.1e-130 fhuC 3.6.3.35 P ABC transporter
ICNLOFLE_02761 2e-58
ICNLOFLE_02762 1.2e-196 S Protein conserved in bacteria
ICNLOFLE_02763 1.8e-262 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
ICNLOFLE_02764 4.5e-191 rgpB GT2 M Glycosyl transferase family 2
ICNLOFLE_02765 2.4e-127 welB S Glycosyltransferase like family 2
ICNLOFLE_02766 2.8e-151 S Glycosyl transferase family 2
ICNLOFLE_02767 1.1e-253 S O-antigen ligase like membrane protein
ICNLOFLE_02768 3.5e-207 gntP EG Gluconate
ICNLOFLE_02769 7.9e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
ICNLOFLE_02770 1.6e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
ICNLOFLE_02771 1.5e-147 gntR K rpiR family
ICNLOFLE_02772 6.4e-170 iolH G Xylose isomerase-like TIM barrel
ICNLOFLE_02773 1.4e-161 iolI 5.3.99.11 G Xylose isomerase-like TIM barrel
ICNLOFLE_02774 1.7e-66 iolK S Tautomerase enzyme
ICNLOFLE_02775 3e-159 iolJ 4.1.2.13, 4.1.2.29 G Fructose-bisphosphate aldolase class-II
ICNLOFLE_02776 3.6e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
ICNLOFLE_02777 4.1e-195 iolG2 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
ICNLOFLE_02778 1.1e-192 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
ICNLOFLE_02779 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
ICNLOFLE_02780 3.8e-179 iolC 2.7.1.92 H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
ICNLOFLE_02781 7.6e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
ICNLOFLE_02782 3e-273 iolA 1.2.1.18, 1.2.1.27 C Belongs to the aldehyde dehydrogenase family
ICNLOFLE_02783 1.1e-267 iolT EGP Major facilitator Superfamily
ICNLOFLE_02784 8.7e-142 iolR K DeoR C terminal sensor domain
ICNLOFLE_02785 3e-164 yvgN C Aldo keto reductase
ICNLOFLE_02786 5.4e-141 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
ICNLOFLE_02787 2.7e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICNLOFLE_02788 1.2e-85 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICNLOFLE_02789 1.3e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ICNLOFLE_02790 1.2e-219 hpk31 2.7.13.3 T Histidine kinase
ICNLOFLE_02791 2.5e-121 K response regulator
ICNLOFLE_02792 1.5e-118
ICNLOFLE_02793 1.9e-267 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICNLOFLE_02794 7.3e-141 XK27_01040 S Protein of unknown function (DUF1129)
ICNLOFLE_02795 2.8e-185 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ICNLOFLE_02796 1.3e-30 yyzM S Bacterial protein of unknown function (DUF951)
ICNLOFLE_02797 2e-155 spo0J K Belongs to the ParB family
ICNLOFLE_02798 2.5e-138 soj D Sporulation initiation inhibitor
ICNLOFLE_02799 2.4e-142 noc K Belongs to the ParB family
ICNLOFLE_02800 2e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
ICNLOFLE_02801 8.4e-66
ICNLOFLE_02802 1e-127 cobQ S glutamine amidotransferase
ICNLOFLE_02804 2.1e-106 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
ICNLOFLE_02805 2.9e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ICNLOFLE_02806 6.7e-146 S Protein of unknown function (DUF979)
ICNLOFLE_02807 6e-115 S Protein of unknown function (DUF969)
ICNLOFLE_02808 5e-127 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
ICNLOFLE_02809 7.9e-65 asp2 S Asp23 family, cell envelope-related function
ICNLOFLE_02810 5.1e-61 asp23 S Asp23 family, cell envelope-related function
ICNLOFLE_02811 1.9e-29
ICNLOFLE_02812 1.5e-89 S Protein conserved in bacteria
ICNLOFLE_02813 6.4e-38 S Transglycosylase associated protein
ICNLOFLE_02814 9.1e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
ICNLOFLE_02815 8.9e-173 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICNLOFLE_02816 6.7e-27
ICNLOFLE_02817 3.4e-36
ICNLOFLE_02818 6.4e-84 fld C Flavodoxin
ICNLOFLE_02819 5.5e-52
ICNLOFLE_02820 2.2e-65
ICNLOFLE_02822 2.7e-56 ywjH S Protein of unknown function (DUF1634)
ICNLOFLE_02823 1.1e-129 yxaA S Sulfite exporter TauE/SafE
ICNLOFLE_02824 1.8e-237 S TPM domain
ICNLOFLE_02825 1.7e-116
ICNLOFLE_02826 3.2e-261 nox 1.6.3.4 C NADH oxidase
ICNLOFLE_02827 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
ICNLOFLE_02828 9.3e-164 gadR K Transcriptional activator, Rgg GadR MutR family
ICNLOFLE_02829 1.4e-284 V ABC transporter transmembrane region
ICNLOFLE_02830 2.1e-213 S nuclear-transcribed mRNA catabolic process, no-go decay
ICNLOFLE_02831 6.2e-42 L Transposase DDE domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)