ORF_ID e_value Gene_name EC_number CAZy COGs Description
IICHHMMA_00001 3.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IICHHMMA_00002 7.8e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IICHHMMA_00003 4.5e-29 yazB K transcriptional
IICHHMMA_00004 2.2e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IICHHMMA_00005 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IICHHMMA_00006 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IICHHMMA_00007 7.9e-160 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
IICHHMMA_00008 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
IICHHMMA_00009 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IICHHMMA_00010 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IICHHMMA_00011 4.5e-155 yacD 5.2.1.8 O peptidyl-prolyl isomerase
IICHHMMA_00012 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IICHHMMA_00013 5.5e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IICHHMMA_00014 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IICHHMMA_00015 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IICHHMMA_00016 1e-270 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IICHHMMA_00017 3.4e-183 KLT serine threonine protein kinase
IICHHMMA_00018 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
IICHHMMA_00019 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
IICHHMMA_00022 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
IICHHMMA_00023 2e-56 divIC D Septum formation initiator
IICHHMMA_00024 2.9e-103 yabQ S spore cortex biosynthesis protein
IICHHMMA_00025 1.9e-49 yabP S Sporulation protein YabP
IICHHMMA_00026 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IICHHMMA_00027 2.8e-274 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IICHHMMA_00028 7.3e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IICHHMMA_00029 8.1e-91 spoVT K stage V sporulation protein
IICHHMMA_00030 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IICHHMMA_00031 3.7e-40 yabK S Peptide ABC transporter permease
IICHHMMA_00032 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IICHHMMA_00033 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IICHHMMA_00034 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IICHHMMA_00035 2.9e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IICHHMMA_00036 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IICHHMMA_00037 4.3e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
IICHHMMA_00038 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IICHHMMA_00039 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IICHHMMA_00040 2.9e-27 sspF S DNA topological change
IICHHMMA_00041 7.8e-39 veg S protein conserved in bacteria
IICHHMMA_00042 5.5e-145 yabG S peptidase
IICHHMMA_00043 1.1e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IICHHMMA_00044 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IICHHMMA_00045 2.6e-226 rpfB GH23 T protein conserved in bacteria
IICHHMMA_00046 2e-143 tatD L hydrolase, TatD
IICHHMMA_00047 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IICHHMMA_00048 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
IICHHMMA_00049 1.3e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IICHHMMA_00050 4.7e-48 yazA L endonuclease containing a URI domain
IICHHMMA_00051 5.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
IICHHMMA_00052 7.7e-37 yabA L Involved in initiation control of chromosome replication
IICHHMMA_00053 8.8e-145 yaaT S stage 0 sporulation protein
IICHHMMA_00054 3.1e-181 holB 2.7.7.7 L DNA polymerase III
IICHHMMA_00055 1.2e-71 yaaR S protein conserved in bacteria
IICHHMMA_00056 7.5e-55 yaaQ S protein conserved in bacteria
IICHHMMA_00057 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IICHHMMA_00058 1.1e-267 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
IICHHMMA_00059 7.9e-189 yaaN P Belongs to the TelA family
IICHHMMA_00060 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IICHHMMA_00061 3.8e-30 csfB S Inhibitor of sigma-G Gin
IICHHMMA_00062 7.8e-08
IICHHMMA_00064 3.9e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IICHHMMA_00065 2.5e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
IICHHMMA_00066 6.5e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
IICHHMMA_00067 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IICHHMMA_00068 2.5e-189 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IICHHMMA_00069 0.0 ydiF S ABC transporter
IICHHMMA_00070 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IICHHMMA_00071 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IICHHMMA_00072 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IICHHMMA_00073 1.8e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IICHHMMA_00074 1.7e-27 ydiK S Domain of unknown function (DUF4305)
IICHHMMA_00075 2.1e-126 ydiL S CAAX protease self-immunity
IICHHMMA_00076 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IICHHMMA_00077 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IICHHMMA_00078 1.1e-46
IICHHMMA_00079 1.2e-165 M nucleic acid phosphodiester bond hydrolysis
IICHHMMA_00080 2.8e-81 3.1.21.3 V Type I restriction modification DNA specificity domain
IICHHMMA_00081 3.4e-286 hsdM 2.1.1.72 V Type I restriction-modification system
IICHHMMA_00082 9.8e-116 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
IICHHMMA_00083 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IICHHMMA_00084 0.0 K NB-ARC domain
IICHHMMA_00085 2.1e-199 gutB 1.1.1.14 E Dehydrogenase
IICHHMMA_00086 1.1e-248 gutA G MFS/sugar transport protein
IICHHMMA_00087 7.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
IICHHMMA_00088 2.1e-30 yjdJ S Domain of unknown function (DUF4306)
IICHHMMA_00089 3.3e-113 pspA KT Phage shock protein A
IICHHMMA_00090 4e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IICHHMMA_00091 1.9e-117 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
IICHHMMA_00092 2.4e-144 ydjI S virion core protein (lumpy skin disease virus)
IICHHMMA_00093 0.0 yrhL I Acyltransferase family
IICHHMMA_00094 1.2e-144 rsiV S Protein of unknown function (DUF3298)
IICHHMMA_00095 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IICHHMMA_00096 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
IICHHMMA_00097 4.2e-62 ydjM M Lytic transglycolase
IICHHMMA_00098 1.8e-134 ydjN U Involved in the tonB-independent uptake of proteins
IICHHMMA_00100 7.2e-35 ydjO S Cold-inducible protein YdjO
IICHHMMA_00101 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
IICHHMMA_00102 6.2e-244 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
IICHHMMA_00103 9.5e-175 yeaC S COG0714 MoxR-like ATPases
IICHHMMA_00104 2.2e-205 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IICHHMMA_00105 0.0 yebA E COG1305 Transglutaminase-like enzymes
IICHHMMA_00106 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IICHHMMA_00107 1.7e-129 K Acetyltransferase (GNAT) domain
IICHHMMA_00108 5e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IICHHMMA_00109 3.3e-248 S Domain of unknown function (DUF4179)
IICHHMMA_00110 8.1e-209 pbuG S permease
IICHHMMA_00111 1.5e-125 yebC M Membrane
IICHHMMA_00113 2e-92 yebE S UPF0316 protein
IICHHMMA_00114 4e-27 yebG S NETI protein
IICHHMMA_00115 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IICHHMMA_00116 3.6e-224 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IICHHMMA_00117 2.4e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IICHHMMA_00118 4.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IICHHMMA_00119 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IICHHMMA_00120 1.1e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IICHHMMA_00121 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IICHHMMA_00122 3.1e-270 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IICHHMMA_00123 1.9e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IICHHMMA_00124 1.2e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IICHHMMA_00125 6.6e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IICHHMMA_00126 1.4e-234 purD 6.3.4.13 F Belongs to the GARS family
IICHHMMA_00127 1.2e-25 S Protein of unknown function (DUF2892)
IICHHMMA_00128 0.0 yerA 3.5.4.2 F adenine deaminase
IICHHMMA_00129 2e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
IICHHMMA_00130 2.4e-50 yerC S protein conserved in bacteria
IICHHMMA_00131 3.7e-301 yerD 1.4.7.1 E Belongs to the glutamate synthase family
IICHHMMA_00132 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IICHHMMA_00133 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IICHHMMA_00134 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IICHHMMA_00135 5.8e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
IICHHMMA_00136 7.5e-191 yerI S homoserine kinase type II (protein kinase fold)
IICHHMMA_00137 4.8e-120 sapB S MgtC SapB transporter
IICHHMMA_00138 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IICHHMMA_00139 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IICHHMMA_00140 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IICHHMMA_00141 2.2e-268 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IICHHMMA_00142 7.1e-150 yerO K Transcriptional regulator
IICHHMMA_00143 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IICHHMMA_00144 1.9e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IICHHMMA_00145 5.4e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IICHHMMA_00146 0.0 K SIR2-like domain
IICHHMMA_00147 4.6e-43 S Immunity protein 22
IICHHMMA_00148 6e-37 S LXG domain of WXG superfamily
IICHHMMA_00149 7.9e-19
IICHHMMA_00150 1e-32 yobL S Bacterial EndoU nuclease
IICHHMMA_00151 2.9e-52 S Protein of unknown function, DUF600
IICHHMMA_00152 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
IICHHMMA_00153 9.4e-127 yeeN K transcriptional regulatory protein
IICHHMMA_00155 1.2e-107 aadK G Streptomycin adenylyltransferase
IICHHMMA_00156 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
IICHHMMA_00157 3.3e-45 cotJB S CotJB protein
IICHHMMA_00158 8.9e-104 cotJC P Spore Coat
IICHHMMA_00159 3.5e-94 yesJ K Acetyltransferase (GNAT) family
IICHHMMA_00161 1.4e-119 yetF S membrane
IICHHMMA_00162 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IICHHMMA_00163 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IICHHMMA_00164 6.4e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IICHHMMA_00165 1.7e-137 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
IICHHMMA_00166 5.8e-112 cysT O COG0555 ABC-type sulfate transport system, permease component
IICHHMMA_00167 1.6e-104 cysW P COG4208 ABC-type sulfate transport system, permease component
IICHHMMA_00168 2.2e-132 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IICHHMMA_00169 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
IICHHMMA_00170 5.3e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
IICHHMMA_00171 1.5e-104 yetJ S Belongs to the BI1 family
IICHHMMA_00172 5.2e-87 yetL K helix_turn_helix multiple antibiotic resistance protein
IICHHMMA_00173 9.3e-206 yetM CH FAD binding domain
IICHHMMA_00174 5.8e-197 yetN S Protein of unknown function (DUF3900)
IICHHMMA_00175 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IICHHMMA_00177 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
IICHHMMA_00178 3.6e-160 V ATPases associated with a variety of cellular activities
IICHHMMA_00179 1.7e-126 V ABC-2 type transporter
IICHHMMA_00181 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IICHHMMA_00182 6.7e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
IICHHMMA_00183 7.1e-172 yfnG 4.2.1.45 M dehydratase
IICHHMMA_00184 7.9e-179 yfnF M Nucleotide-diphospho-sugar transferase
IICHHMMA_00185 8.1e-221 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
IICHHMMA_00186 6.9e-186 yfnD M Nucleotide-diphospho-sugar transferase
IICHHMMA_00187 2.3e-218 fsr P COG0477 Permeases of the major facilitator superfamily
IICHHMMA_00188 1e-246 yfnA E amino acid
IICHHMMA_00189 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IICHHMMA_00190 7.5e-107 yfmS NT chemotaxis protein
IICHHMMA_00191 5.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
IICHHMMA_00192 5.5e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IICHHMMA_00193 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IICHHMMA_00194 1.8e-69 yfmP K transcriptional
IICHHMMA_00195 2.6e-206 yfmO EGP Major facilitator Superfamily
IICHHMMA_00196 3.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IICHHMMA_00197 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
IICHHMMA_00198 5.7e-66 yfmK 2.3.1.128 K acetyltransferase
IICHHMMA_00199 3e-187 yfmJ S N-terminal domain of oxidoreductase
IICHHMMA_00200 1.2e-24 S Protein of unknown function (DUF3212)
IICHHMMA_00201 1.3e-57 yflT S Heat induced stress protein YflT
IICHHMMA_00202 1.5e-241 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
IICHHMMA_00203 1e-233 yflS P Sodium:sulfate symporter transmembrane region
IICHHMMA_00204 1.5e-26 Q PFAM Collagen triple helix
IICHHMMA_00206 2.3e-47 Q calcium- and calmodulin-responsive adenylate cyclase activity
IICHHMMA_00208 6.8e-220 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
IICHHMMA_00209 6.8e-165 cgeB S Spore maturation protein
IICHHMMA_00210 1.1e-53 cgeA
IICHHMMA_00211 3.6e-40 cgeC
IICHHMMA_00212 6.3e-243 cgeD M maturation of the outermost layer of the spore
IICHHMMA_00213 3.7e-145 yiiD K acetyltransferase
IICHHMMA_00215 5.4e-16 yosT L Bacterial transcription activator, effector binding domain
IICHHMMA_00216 6.4e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IICHHMMA_00217 2.2e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IICHHMMA_00218 2.3e-122 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IICHHMMA_00219 1.6e-254 yodQ 3.5.1.16 E Acetylornithine deacetylase
IICHHMMA_00220 3.1e-156 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
IICHHMMA_00221 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
IICHHMMA_00222 2e-45 yokU S YokU-like protein, putative antitoxin
IICHHMMA_00223 2.6e-35 yozE S Belongs to the UPF0346 family
IICHHMMA_00224 1.7e-125 yodN
IICHHMMA_00226 6.2e-24 yozD S YozD-like protein
IICHHMMA_00227 1.1e-102 yodM 3.6.1.27 I Acid phosphatase homologues
IICHHMMA_00228 3.3e-55 yodL S YodL-like
IICHHMMA_00230 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IICHHMMA_00231 1.1e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IICHHMMA_00232 1.9e-21 yodI
IICHHMMA_00233 2.8e-128 yodH Q Methyltransferase
IICHHMMA_00234 1.8e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IICHHMMA_00235 5.7e-132 yydK K Transcriptional regulator
IICHHMMA_00236 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IICHHMMA_00237 5.7e-280 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
IICHHMMA_00238 8.5e-255 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IICHHMMA_00239 1.4e-19 S Protein of unknown function (DUF3311)
IICHHMMA_00240 7.7e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
IICHHMMA_00241 3.7e-108 mhqD S Carboxylesterase
IICHHMMA_00242 1.7e-105 yodC C nitroreductase
IICHHMMA_00243 3e-56 yodB K transcriptional
IICHHMMA_00244 2.7e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
IICHHMMA_00245 1.6e-67 yodA S tautomerase
IICHHMMA_00247 7.3e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
IICHHMMA_00248 1.1e-161 rarD S -transporter
IICHHMMA_00249 4.9e-23
IICHHMMA_00250 3.7e-60 yojF S Protein of unknown function (DUF1806)
IICHHMMA_00251 9.6e-126 yojG S deacetylase
IICHHMMA_00252 2.9e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IICHHMMA_00253 6.1e-236 norM V Multidrug efflux pump
IICHHMMA_00255 6.3e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IICHHMMA_00256 2.1e-224 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
IICHHMMA_00257 6.8e-226 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IICHHMMA_00258 2.9e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IICHHMMA_00259 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
IICHHMMA_00260 0.0 yojO P Von Willebrand factor
IICHHMMA_00261 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IICHHMMA_00262 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IICHHMMA_00263 5.3e-141 S Metallo-beta-lactamase superfamily
IICHHMMA_00264 4.3e-159 yocS S -transporter
IICHHMMA_00265 4.3e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IICHHMMA_00266 4.1e-166 sodA 1.15.1.1 P Superoxide dismutase
IICHHMMA_00267 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
IICHHMMA_00268 2.2e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
IICHHMMA_00269 3.6e-31 yozC
IICHHMMA_00271 2.4e-56 yozO S Bacterial PH domain
IICHHMMA_00272 8.5e-37 yocN
IICHHMMA_00273 3.8e-44 yozN
IICHHMMA_00274 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
IICHHMMA_00275 1.3e-08
IICHHMMA_00276 2.3e-09 yocL
IICHHMMA_00277 2.5e-54 dksA T general stress protein
IICHHMMA_00279 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IICHHMMA_00280 0.0 recQ 3.6.4.12 L DNA helicase
IICHHMMA_00281 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
IICHHMMA_00283 1.4e-186 yocD 3.4.17.13 V peptidase S66
IICHHMMA_00284 1.6e-93 yocC
IICHHMMA_00285 5.8e-138 yocB J Protein required for attachment to host cells
IICHHMMA_00286 3.6e-91 yozB S membrane
IICHHMMA_00287 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IICHHMMA_00288 1.7e-54 czrA K transcriptional
IICHHMMA_00289 2.7e-91 yobW
IICHHMMA_00290 1.1e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
IICHHMMA_00291 1.8e-93 yobS K Transcriptional regulator
IICHHMMA_00292 3e-133 yobQ K helix_turn_helix, arabinose operon control protein
IICHHMMA_00293 2.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
IICHHMMA_00294 3.4e-61 ykvN K Transcriptional regulator
IICHHMMA_00295 9.4e-130 IQ Enoyl-(Acyl carrier protein) reductase
IICHHMMA_00296 1.9e-43
IICHHMMA_00297 6.9e-96 hpr K helix_turn_helix multiple antibiotic resistance protein
IICHHMMA_00299 4.5e-24 yoaF
IICHHMMA_00300 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IICHHMMA_00301 2.5e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IICHHMMA_00302 1.8e-270 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
IICHHMMA_00303 7.4e-204 yoaB EGP Major facilitator Superfamily
IICHHMMA_00304 4.2e-133 yoxB
IICHHMMA_00305 9.8e-41 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IICHHMMA_00306 4.8e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IICHHMMA_00307 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IICHHMMA_00308 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IICHHMMA_00309 3.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IICHHMMA_00310 1.3e-149 gltC K Transcriptional regulator
IICHHMMA_00311 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
IICHHMMA_00312 4.2e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IICHHMMA_00313 2.3e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IICHHMMA_00314 1.2e-152 gltR1 K Transcriptional regulator
IICHHMMA_00315 3.2e-270 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IICHHMMA_00316 1.8e-50 ybzH K Helix-turn-helix domain
IICHHMMA_00317 2e-198 ybcL EGP Major facilitator Superfamily
IICHHMMA_00318 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IICHHMMA_00319 1.8e-34 yoeD G Helix-turn-helix domain
IICHHMMA_00320 3.5e-97 L Integrase
IICHHMMA_00322 1.9e-95 yoeB S IseA DL-endopeptidase inhibitor
IICHHMMA_00323 2.3e-246 yoeA V MATE efflux family protein
IICHHMMA_00324 2.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
IICHHMMA_00325 5.4e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
IICHHMMA_00326 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_00327 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_00328 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_00329 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_00330 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
IICHHMMA_00331 1.2e-64 yngL S Protein of unknown function (DUF1360)
IICHHMMA_00332 5.6e-302 yngK T Glycosyl hydrolase-like 10
IICHHMMA_00333 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
IICHHMMA_00334 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IICHHMMA_00335 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
IICHHMMA_00336 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
IICHHMMA_00337 1.8e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
IICHHMMA_00338 6.8e-139 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IICHHMMA_00339 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IICHHMMA_00340 3.2e-104 yngC S SNARE associated Golgi protein
IICHHMMA_00341 2e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IICHHMMA_00342 4.7e-67 yngA S membrane
IICHHMMA_00343 4.3e-146 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IICHHMMA_00344 5.1e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IICHHMMA_00345 4e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IICHHMMA_00346 4.5e-126 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IICHHMMA_00347 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IICHHMMA_00348 1.1e-215 bioI 1.14.14.46 C Cytochrome P450
IICHHMMA_00349 1.9e-251 yxjC EG COG2610 H gluconate symporter and related permeases
IICHHMMA_00350 9.9e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IICHHMMA_00351 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IICHHMMA_00352 5.4e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IICHHMMA_00353 2.8e-216 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IICHHMMA_00354 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_00355 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_00356 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_00357 1.9e-286 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
IICHHMMA_00358 1.7e-251 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
IICHHMMA_00359 2.9e-128 T Transcriptional regulatory protein, C terminal
IICHHMMA_00360 9.4e-232 T PhoQ Sensor
IICHHMMA_00361 6.9e-50 S Domain of unknown function (DUF4870)
IICHHMMA_00362 1.4e-281 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
IICHHMMA_00363 7.9e-213 S Platelet-activating factor acetylhydrolase, isoform II
IICHHMMA_00364 1.9e-292 yndJ S YndJ-like protein
IICHHMMA_00365 6.2e-79 yndH S Domain of unknown function (DUF4166)
IICHHMMA_00366 1.9e-155 yndG S DoxX-like family
IICHHMMA_00367 3.3e-136 exuT G Sugar (and other) transporter
IICHHMMA_00368 2.1e-71 exuT G Sugar (and other) transporter
IICHHMMA_00369 3.5e-180 kdgR_1 K transcriptional
IICHHMMA_00370 1.2e-144 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IICHHMMA_00371 5.1e-59 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
IICHHMMA_00372 7.4e-112 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
IICHHMMA_00373 5.8e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
IICHHMMA_00374 2.6e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
IICHHMMA_00375 2e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
IICHHMMA_00376 8.9e-246 agcS E Sodium alanine symporter
IICHHMMA_00377 5.1e-41 ynfC
IICHHMMA_00378 6e-13
IICHHMMA_00379 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IICHHMMA_00380 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IICHHMMA_00381 1.5e-68 yccU S CoA-binding protein
IICHHMMA_00382 1.2e-92 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IICHHMMA_00383 1.3e-50 yneR S Belongs to the HesB IscA family
IICHHMMA_00384 1.4e-52 yneQ
IICHHMMA_00385 9.1e-74 yneP S Thioesterase-like superfamily
IICHHMMA_00386 7.1e-18 tlp S Belongs to the Tlp family
IICHHMMA_00389 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IICHHMMA_00390 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IICHHMMA_00391 7.5e-15 sspO S Belongs to the SspO family
IICHHMMA_00392 2.3e-19 sspP S Belongs to the SspP family
IICHHMMA_00393 1.1e-62 hspX O Spore coat protein
IICHHMMA_00394 2.5e-74 yneK S Protein of unknown function (DUF2621)
IICHHMMA_00395 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
IICHHMMA_00396 1.8e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
IICHHMMA_00397 1.7e-125 ccdA O cytochrome c biogenesis protein
IICHHMMA_00398 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
IICHHMMA_00399 2.3e-28 yneF S UPF0154 protein
IICHHMMA_00400 6.3e-81 yneE S Sporulation inhibitor of replication protein sirA
IICHHMMA_00401 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IICHHMMA_00402 9.8e-33 ynzC S UPF0291 protein
IICHHMMA_00403 3.5e-112 yneB L resolvase
IICHHMMA_00404 8.1e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IICHHMMA_00405 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IICHHMMA_00406 7.1e-13 yoaW
IICHHMMA_00407 2.4e-72 yndM S Protein of unknown function (DUF2512)
IICHHMMA_00408 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
IICHHMMA_00409 9.1e-08
IICHHMMA_00410 1.2e-141 yndL S Replication protein
IICHHMMA_00411 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
IICHHMMA_00412 0.0 yobO M Pectate lyase superfamily protein
IICHHMMA_00414 6.6e-93 yvgO
IICHHMMA_00417 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
IICHHMMA_00418 7.8e-202 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IICHHMMA_00419 5e-116 ynaE S Domain of unknown function (DUF3885)
IICHHMMA_00420 2.8e-99 J Acetyltransferase (GNAT) domain
IICHHMMA_00421 2.9e-142 yoaP 3.1.3.18 K YoaP-like
IICHHMMA_00423 1e-09
IICHHMMA_00424 1.1e-186 adhP 1.1.1.1 C alcohol dehydrogenase
IICHHMMA_00427 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
IICHHMMA_00428 2.7e-285 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
IICHHMMA_00429 6.2e-257 xylA 5.3.1.5 G Belongs to the xylose isomerase family
IICHHMMA_00430 7.1e-209 xylR GK ROK family
IICHHMMA_00431 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
IICHHMMA_00432 8.4e-249 xynT G MFS/sugar transport protein
IICHHMMA_00433 3e-209 mrjp G Major royal jelly protein
IICHHMMA_00434 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
IICHHMMA_00435 4.3e-68 glnR K transcriptional
IICHHMMA_00436 6.3e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IICHHMMA_00437 7.2e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IICHHMMA_00438 1.3e-176 spoVK O stage V sporulation protein K
IICHHMMA_00439 1.4e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IICHHMMA_00440 3.4e-109 ymaB S MutT family
IICHHMMA_00441 4.7e-185 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IICHHMMA_00442 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IICHHMMA_00443 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
IICHHMMA_00444 1.8e-20 ymzA
IICHHMMA_00445 4.7e-42
IICHHMMA_00446 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IICHHMMA_00447 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IICHHMMA_00448 1.2e-46 ymaF S YmaF family
IICHHMMA_00450 2.6e-47 ebrA P Small Multidrug Resistance protein
IICHHMMA_00451 2.6e-53 ebrB P Small Multidrug Resistance protein
IICHHMMA_00452 7.8e-79 ymaD O redox protein, regulator of disulfide bond formation
IICHHMMA_00453 3e-125 ymaC S Replication protein
IICHHMMA_00455 2.6e-255 aprX O Belongs to the peptidase S8 family
IICHHMMA_00456 4.1e-62 ymzB
IICHHMMA_00457 5.9e-118 yoaK S Membrane
IICHHMMA_00458 4.9e-78 nucB M Deoxyribonuclease NucA/NucB
IICHHMMA_00459 1.6e-227 cypA C Cytochrome P450
IICHHMMA_00460 0.0 pks13 HQ Beta-ketoacyl synthase
IICHHMMA_00461 0.0 dhbF IQ polyketide synthase
IICHHMMA_00462 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
IICHHMMA_00463 0.0 Q Polyketide synthase of type I
IICHHMMA_00464 0.0 rhiB IQ polyketide synthase
IICHHMMA_00465 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IICHHMMA_00466 4.1e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
IICHHMMA_00467 2.4e-242 pksG 2.3.3.10 I synthase
IICHHMMA_00468 2.5e-34 acpK IQ Phosphopantetheine attachment site
IICHHMMA_00469 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IICHHMMA_00470 1.1e-183 pksD Q Acyl transferase domain
IICHHMMA_00471 8.3e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IICHHMMA_00472 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
IICHHMMA_00474 2.6e-08 L phage terminase small subunit
IICHHMMA_00477 1.9e-32 S Domain of unknown function (DUF4393)
IICHHMMA_00478 2e-16 L Phage integrase family
IICHHMMA_00479 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IICHHMMA_00480 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IICHHMMA_00481 1.7e-88 cotE S Spore coat protein
IICHHMMA_00482 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IICHHMMA_00483 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IICHHMMA_00484 1.5e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IICHHMMA_00485 9.6e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IICHHMMA_00486 1.2e-36 spoVS S Stage V sporulation protein S
IICHHMMA_00487 4.9e-153 ymdB S protein conserved in bacteria
IICHHMMA_00488 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
IICHHMMA_00489 9.5e-193 pbpX V Beta-lactamase
IICHHMMA_00490 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IICHHMMA_00491 1.6e-230 cinA 3.5.1.42 S Belongs to the CinA family
IICHHMMA_00492 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IICHHMMA_00493 7.8e-126 ymfM S protein conserved in bacteria
IICHHMMA_00494 1e-142 ymfK S Protein of unknown function (DUF3388)
IICHHMMA_00495 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
IICHHMMA_00496 6.6e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IICHHMMA_00497 9.2e-242 ymfH S zinc protease
IICHHMMA_00498 4e-237 ymfF S Peptidase M16
IICHHMMA_00499 0.0 ydgH S drug exporters of the RND superfamily
IICHHMMA_00500 1.4e-75 K helix_turn_helix multiple antibiotic resistance protein
IICHHMMA_00501 2.6e-195 ymfD EGP Major facilitator Superfamily
IICHHMMA_00502 2.6e-132 ymfC K Transcriptional regulator
IICHHMMA_00503 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IICHHMMA_00504 1.4e-30 S YlzJ-like protein
IICHHMMA_00505 2.3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
IICHHMMA_00506 1.7e-307 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IICHHMMA_00507 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IICHHMMA_00508 2.1e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IICHHMMA_00509 2.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IICHHMMA_00510 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IICHHMMA_00511 4.7e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
IICHHMMA_00512 2.6e-42 ymxH S YlmC YmxH family
IICHHMMA_00513 1.2e-233 pepR S Belongs to the peptidase M16 family
IICHHMMA_00514 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
IICHHMMA_00515 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IICHHMMA_00516 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IICHHMMA_00517 3.5e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IICHHMMA_00518 1.1e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IICHHMMA_00519 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IICHHMMA_00520 3.9e-44 ylxP S protein conserved in bacteria
IICHHMMA_00521 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IICHHMMA_00522 1.8e-47 ylxQ J ribosomal protein
IICHHMMA_00523 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
IICHHMMA_00524 5.4e-206 nusA K Participates in both transcription termination and antitermination
IICHHMMA_00525 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
IICHHMMA_00526 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IICHHMMA_00527 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IICHHMMA_00528 5.9e-233 rasP M zinc metalloprotease
IICHHMMA_00529 9.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IICHHMMA_00530 4.9e-137 cdsA 2.7.7.41 S Belongs to the CDS family
IICHHMMA_00531 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IICHHMMA_00532 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IICHHMMA_00533 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IICHHMMA_00534 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IICHHMMA_00535 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
IICHHMMA_00536 3e-49 ylxL
IICHHMMA_00537 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IICHHMMA_00538 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IICHHMMA_00539 3.7e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IICHHMMA_00540 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
IICHHMMA_00541 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
IICHHMMA_00542 1.1e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IICHHMMA_00543 6.3e-157 flhG D Belongs to the ParA family
IICHHMMA_00544 8.2e-191 flhF N Flagellar biosynthesis regulator FlhF
IICHHMMA_00545 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IICHHMMA_00546 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IICHHMMA_00547 5.2e-131 fliR N Flagellar biosynthetic protein FliR
IICHHMMA_00548 2e-37 fliQ N Role in flagellar biosynthesis
IICHHMMA_00549 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
IICHHMMA_00550 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
IICHHMMA_00551 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
IICHHMMA_00552 6.2e-186 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IICHHMMA_00553 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IICHHMMA_00554 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
IICHHMMA_00555 5.7e-138 flgG N Flagellar basal body rod
IICHHMMA_00556 2.4e-72 flgD N Flagellar basal body rod modification protein
IICHHMMA_00557 9.1e-200 fliK N Flagellar hook-length control protein
IICHHMMA_00558 1.3e-47 ylxF S MgtE intracellular N domain
IICHHMMA_00559 2e-71 fliJ N Flagellar biosynthesis chaperone
IICHHMMA_00560 1.6e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IICHHMMA_00561 1.3e-86 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
IICHHMMA_00562 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IICHHMMA_00563 3.1e-263 fliF N The M ring may be actively involved in energy transduction
IICHHMMA_00564 2.5e-31 fliE N Flagellar hook-basal body
IICHHMMA_00565 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
IICHHMMA_00566 6.8e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IICHHMMA_00567 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IICHHMMA_00568 2.7e-231 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IICHHMMA_00569 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IICHHMMA_00570 7.2e-172 xerC L tyrosine recombinase XerC
IICHHMMA_00571 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IICHHMMA_00572 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IICHHMMA_00573 3.1e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
IICHHMMA_00574 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IICHHMMA_00575 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IICHHMMA_00576 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
IICHHMMA_00577 4.7e-302 ylqG
IICHHMMA_00578 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IICHHMMA_00579 1.9e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IICHHMMA_00580 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IICHHMMA_00581 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IICHHMMA_00582 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IICHHMMA_00583 1.3e-61 ylqD S YlqD protein
IICHHMMA_00584 1.7e-35 ylqC S Belongs to the UPF0109 family
IICHHMMA_00585 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IICHHMMA_00586 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IICHHMMA_00587 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IICHHMMA_00588 1e-139 S Phosphotransferase enzyme family
IICHHMMA_00589 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IICHHMMA_00590 0.0 smc D Required for chromosome condensation and partitioning
IICHHMMA_00591 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IICHHMMA_00592 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IICHHMMA_00593 4.6e-129 IQ reductase
IICHHMMA_00594 2.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IICHHMMA_00595 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IICHHMMA_00596 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IICHHMMA_00597 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IICHHMMA_00598 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
IICHHMMA_00599 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
IICHHMMA_00600 1.4e-303 yloV S kinase related to dihydroxyacetone kinase
IICHHMMA_00601 5.5e-59 asp S protein conserved in bacteria
IICHHMMA_00602 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IICHHMMA_00603 4.9e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
IICHHMMA_00604 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IICHHMMA_00605 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IICHHMMA_00606 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IICHHMMA_00607 1.1e-138 stp 3.1.3.16 T phosphatase
IICHHMMA_00608 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IICHHMMA_00609 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IICHHMMA_00610 1.7e-168 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IICHHMMA_00611 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IICHHMMA_00612 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IICHHMMA_00613 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IICHHMMA_00614 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IICHHMMA_00615 2.3e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IICHHMMA_00616 1.5e-40 ylzA S Belongs to the UPF0296 family
IICHHMMA_00617 8.5e-154 yloC S stress-induced protein
IICHHMMA_00618 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
IICHHMMA_00619 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IICHHMMA_00621 1.2e-77 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
IICHHMMA_00622 4.1e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
IICHHMMA_00623 1.2e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IICHHMMA_00624 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
IICHHMMA_00625 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
IICHHMMA_00626 1.1e-176 cysP P phosphate transporter
IICHHMMA_00627 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
IICHHMMA_00628 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IICHHMMA_00629 1e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IICHHMMA_00630 6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IICHHMMA_00631 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IICHHMMA_00632 0.0 carB 6.3.5.5 F Belongs to the CarB family
IICHHMMA_00633 6.1e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IICHHMMA_00634 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IICHHMMA_00635 4.1e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IICHHMMA_00636 8e-233 pyrP F Xanthine uracil
IICHHMMA_00637 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IICHHMMA_00638 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IICHHMMA_00639 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IICHHMMA_00640 3.8e-63 dksA T COG1734 DnaK suppressor protein
IICHHMMA_00641 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IICHHMMA_00642 8.9e-68 divIVA D Cell division initiation protein
IICHHMMA_00643 1.6e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
IICHHMMA_00644 5.2e-41 yggT S membrane
IICHHMMA_00645 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IICHHMMA_00646 4.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IICHHMMA_00647 4.4e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
IICHHMMA_00648 2.2e-38 ylmC S sporulation protein
IICHHMMA_00649 7.9e-250 argE 3.5.1.16 E Acetylornithine deacetylase
IICHHMMA_00650 7.9e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IICHHMMA_00651 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IICHHMMA_00652 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IICHHMMA_00653 2.2e-160 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IICHHMMA_00654 0.0 bpr O COG1404 Subtilisin-like serine proteases
IICHHMMA_00655 5.8e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IICHHMMA_00656 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IICHHMMA_00657 4.8e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IICHHMMA_00658 3.7e-168 murB 1.3.1.98 M cell wall formation
IICHHMMA_00659 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IICHHMMA_00660 2.2e-185 spoVE D Belongs to the SEDS family
IICHHMMA_00661 8.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IICHHMMA_00662 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IICHHMMA_00663 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IICHHMMA_00664 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
IICHHMMA_00665 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IICHHMMA_00666 2.9e-52 ftsL D Essential cell division protein
IICHHMMA_00667 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IICHHMMA_00668 1.2e-77 mraZ K Belongs to the MraZ family
IICHHMMA_00669 3.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IICHHMMA_00670 1.6e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IICHHMMA_00671 1.2e-88 ylbP K n-acetyltransferase
IICHHMMA_00672 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IICHHMMA_00673 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IICHHMMA_00674 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
IICHHMMA_00675 5.6e-228 ylbM S Belongs to the UPF0348 family
IICHHMMA_00676 1.6e-188 ylbL T Belongs to the peptidase S16 family
IICHHMMA_00677 4.4e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
IICHHMMA_00678 2.2e-216 ylbJ S Sporulation integral membrane protein YlbJ
IICHHMMA_00679 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IICHHMMA_00680 2.7e-97 rsmD 2.1.1.171 L Methyltransferase
IICHHMMA_00682 5.5e-43 ylbG S UPF0298 protein
IICHHMMA_00683 1.2e-71 ylbF S Belongs to the UPF0342 family
IICHHMMA_00684 8.8e-37 ylbE S YlbE-like protein
IICHHMMA_00685 1.9e-55 ylbD S Putative coat protein
IICHHMMA_00686 2.3e-198 ylbC S protein with SCP PR1 domains
IICHHMMA_00687 2.2e-73 ylbB T COG0517 FOG CBS domain
IICHHMMA_00688 3.2e-59 ylbA S YugN-like family
IICHHMMA_00689 2e-163 ctaG S cytochrome c oxidase
IICHHMMA_00690 1e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IICHHMMA_00691 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IICHHMMA_00692 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IICHHMMA_00693 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IICHHMMA_00694 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IICHHMMA_00695 4.5e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IICHHMMA_00696 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IICHHMMA_00697 1.9e-212 ftsW D Belongs to the SEDS family
IICHHMMA_00698 8.7e-44 ylaN S Belongs to the UPF0358 family
IICHHMMA_00699 1.3e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
IICHHMMA_00700 3.2e-83 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IICHHMMA_00701 1.3e-243 phoH T ATPase related to phosphate starvation-inducible protein PhoH
IICHHMMA_00702 2.6e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IICHHMMA_00703 1.4e-33 ylaI S protein conserved in bacteria
IICHHMMA_00704 6.6e-48 ylaH S YlaH-like protein
IICHHMMA_00705 0.0 typA T GTP-binding protein TypA
IICHHMMA_00706 6.7e-24 S Family of unknown function (DUF5325)
IICHHMMA_00707 7.3e-35 ylaE
IICHHMMA_00708 8.3e-13 sigC S Putative zinc-finger
IICHHMMA_00709 9.7e-294 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
IICHHMMA_00710 2e-82 ykzC S Acetyltransferase (GNAT) family
IICHHMMA_00711 1e-150 suhB 3.1.3.25 G Inositol monophosphatase
IICHHMMA_00712 6.3e-24 ykzI
IICHHMMA_00713 3.1e-118 yktB S Belongs to the UPF0637 family
IICHHMMA_00714 5.9e-42 yktA S Belongs to the UPF0223 family
IICHHMMA_00715 4.7e-274 speA 4.1.1.19 E Arginine
IICHHMMA_00716 2.6e-130 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
IICHHMMA_00717 8.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
IICHHMMA_00718 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IICHHMMA_00719 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IICHHMMA_00720 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IICHHMMA_00721 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IICHHMMA_00722 8.7e-209 V Beta-lactamase
IICHHMMA_00723 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
IICHHMMA_00724 0.0 Q Polyketide synthase of type I
IICHHMMA_00725 0.0 Q Polyketide synthase of type I
IICHHMMA_00726 0.0 Q Polyketide synthase of type I
IICHHMMA_00727 0.0 Q Polyketide synthase of type I
IICHHMMA_00728 0.0 Q polyketide synthase
IICHHMMA_00729 0.0 Q Polyketide synthase of type I
IICHHMMA_00730 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IICHHMMA_00731 7.9e-101 recN L Putative cell-wall binding lipoprotein
IICHHMMA_00733 1.7e-99 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IICHHMMA_00734 2e-146 ykrA S hydrolases of the HAD superfamily
IICHHMMA_00735 8.2e-31 ykzG S Belongs to the UPF0356 family
IICHHMMA_00736 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IICHHMMA_00737 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IICHHMMA_00738 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
IICHHMMA_00739 1.9e-147 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
IICHHMMA_00740 3.4e-244 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
IICHHMMA_00741 1.8e-44 abrB K of stationary sporulation gene expression
IICHHMMA_00742 6.9e-184 mreB D Rod-share determining protein MreBH
IICHHMMA_00743 5.5e-12 S Uncharacterized protein YkpC
IICHHMMA_00744 1.9e-236 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IICHHMMA_00745 7.9e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IICHHMMA_00746 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IICHHMMA_00747 9.8e-37 ykoA
IICHHMMA_00748 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IICHHMMA_00749 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IICHHMMA_00750 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
IICHHMMA_00751 2.3e-131 fruR K Transcriptional regulator
IICHHMMA_00752 5.1e-210 yknZ V ABC transporter (permease)
IICHHMMA_00753 3.9e-122 macB V ABC transporter, ATP-binding protein
IICHHMMA_00754 6e-168 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IICHHMMA_00755 3e-101 yknW S Yip1 domain
IICHHMMA_00756 5.7e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IICHHMMA_00757 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
IICHHMMA_00758 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IICHHMMA_00759 4.9e-243 moeA 2.10.1.1 H molybdopterin
IICHHMMA_00760 5.5e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IICHHMMA_00761 1.4e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IICHHMMA_00762 2.8e-161 yknT
IICHHMMA_00763 1.1e-96 rok K Repressor of ComK
IICHHMMA_00764 7e-75 ykuV CO thiol-disulfide
IICHHMMA_00765 1.3e-140 ykuT M Mechanosensitive ion channel
IICHHMMA_00766 4.8e-38 ykuS S Belongs to the UPF0180 family
IICHHMMA_00767 7.6e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IICHHMMA_00768 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IICHHMMA_00769 6e-79 fld C Flavodoxin
IICHHMMA_00770 8e-168 ykuO
IICHHMMA_00771 2.5e-88 fld C Flavodoxin
IICHHMMA_00772 4.6e-168 ccpC K Transcriptional regulator
IICHHMMA_00773 1e-75 ykuL S CBS domain
IICHHMMA_00774 2.5e-26 ykzF S Antirepressor AbbA
IICHHMMA_00775 1.7e-93 ykuK S Ribonuclease H-like
IICHHMMA_00776 3.9e-37 ykuJ S protein conserved in bacteria
IICHHMMA_00777 3.3e-233 ykuI T Diguanylate phosphodiesterase
IICHHMMA_00779 1.4e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IICHHMMA_00780 2e-152 ykuE S Metallophosphoesterase
IICHHMMA_00781 4.1e-89 ykuD S protein conserved in bacteria
IICHHMMA_00782 3.3e-239 ykuC EGP Major facilitator Superfamily
IICHHMMA_00783 1.4e-83 ykyB S YkyB-like protein
IICHHMMA_00784 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
IICHHMMA_00785 2.6e-08
IICHHMMA_00786 3.9e-215 patA 2.6.1.1 E Aminotransferase
IICHHMMA_00787 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
IICHHMMA_00788 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
IICHHMMA_00789 8.9e-115 ykwD J protein with SCP PR1 domains
IICHHMMA_00790 9.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IICHHMMA_00791 1.3e-263 mcpC NT chemotaxis protein
IICHHMMA_00792 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
IICHHMMA_00793 6.1e-38 splA S Transcriptional regulator
IICHHMMA_00794 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IICHHMMA_00795 2.1e-39 ptsH G phosphocarrier protein HPr
IICHHMMA_00796 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IICHHMMA_00797 5.1e-156 glcT K antiterminator
IICHHMMA_00798 5.6e-175 ykvZ 5.1.1.1 K Transcriptional regulator
IICHHMMA_00800 2.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IICHHMMA_00801 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IICHHMMA_00802 3.2e-86 stoA CO thiol-disulfide
IICHHMMA_00803 4e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IICHHMMA_00804 2.4e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
IICHHMMA_00805 2.3e-27
IICHHMMA_00806 7.8e-25 ykvS S protein conserved in bacteria
IICHHMMA_00807 1.3e-44 ykvR S Protein of unknown function (DUF3219)
IICHHMMA_00808 3.9e-44 gph 3.1.3.18 K HAD-hyrolase-like
IICHHMMA_00809 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IICHHMMA_00810 2.2e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IICHHMMA_00811 4.9e-78 queD 4.1.2.50, 4.2.3.12 H synthase
IICHHMMA_00812 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IICHHMMA_00813 4.8e-186
IICHHMMA_00814 8.6e-182 ykvI S membrane
IICHHMMA_00815 0.0 clpE O Belongs to the ClpA ClpB family
IICHHMMA_00816 3.3e-136 motA N flagellar motor
IICHHMMA_00817 1.5e-125 motB N Flagellar motor protein
IICHHMMA_00818 5.5e-77 ykvE K transcriptional
IICHHMMA_00819 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
IICHHMMA_00820 3.4e-10 S Spo0E like sporulation regulatory protein
IICHHMMA_00821 2.1e-94 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IICHHMMA_00822 3e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IICHHMMA_00823 6e-134 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IICHHMMA_00824 2.3e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IICHHMMA_00825 2.1e-224 mtnE 2.6.1.83 E Aminotransferase
IICHHMMA_00826 1.1e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IICHHMMA_00827 9.4e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IICHHMMA_00828 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IICHHMMA_00830 2.5e-86 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IICHHMMA_00831 0.0 kinE 2.7.13.3 T Histidine kinase
IICHHMMA_00832 5.2e-187 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
IICHHMMA_00833 8.7e-23 ykzE
IICHHMMA_00834 6.1e-112 ydfR S Protein of unknown function (DUF421)
IICHHMMA_00835 3.1e-240 ktrB P COG0168 Trk-type K transport systems, membrane components
IICHHMMA_00836 4.1e-156 htpX O Belongs to the peptidase M48B family
IICHHMMA_00837 2.3e-125 ykrK S Domain of unknown function (DUF1836)
IICHHMMA_00838 2.5e-26 sspD S small acid-soluble spore protein
IICHHMMA_00839 9e-119 rsgI S Anti-sigma factor N-terminus
IICHHMMA_00840 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IICHHMMA_00841 1.2e-132 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IICHHMMA_00842 3.3e-90 ykoX S membrane-associated protein
IICHHMMA_00843 4.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IICHHMMA_00844 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
IICHHMMA_00845 8.3e-99 ykoP G polysaccharide deacetylase
IICHHMMA_00846 1.1e-80 ykoM K transcriptional
IICHHMMA_00847 3.1e-26 ykoL
IICHHMMA_00848 1.9e-16
IICHHMMA_00849 5.4e-53 tnrA K transcriptional
IICHHMMA_00850 3.2e-237 mgtE P Acts as a magnesium transporter
IICHHMMA_00852 7.4e-244 ydhD M Glycosyl hydrolase
IICHHMMA_00853 1e-97 ykoE S ABC-type cobalt transport system, permease component
IICHHMMA_00854 7.7e-302 P ABC transporter, ATP-binding protein
IICHHMMA_00855 2.1e-132 ykoC P Cobalt transport protein
IICHHMMA_00856 6.6e-148 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IICHHMMA_00857 5e-176 isp O Belongs to the peptidase S8 family
IICHHMMA_00858 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IICHHMMA_00859 3.7e-120 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IICHHMMA_00860 3.7e-87 hcaT 1.5.1.2 EGP Major facilitator Superfamily
IICHHMMA_00861 1.8e-102 hcaT 1.5.1.2 EGP Major facilitator Superfamily
IICHHMMA_00862 2.7e-125 M PFAM Collagen triple helix repeat (20 copies)
IICHHMMA_00863 8.4e-215 M Glycosyl transferase family 2
IICHHMMA_00865 3e-54 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IICHHMMA_00866 4.2e-71 ohrB O Organic hydroperoxide resistance protein
IICHHMMA_00867 1.6e-75 ohrR K COG1846 Transcriptional regulators
IICHHMMA_00868 4.1e-69 ohrA O Organic hydroperoxide resistance protein
IICHHMMA_00869 5.8e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IICHHMMA_00870 2.7e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IICHHMMA_00871 4.3e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IICHHMMA_00872 1e-48 ykkD P Multidrug resistance protein
IICHHMMA_00873 8e-52 ykkC P Multidrug resistance protein
IICHHMMA_00874 1.7e-99 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IICHHMMA_00875 9.2e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
IICHHMMA_00876 1.6e-157 ykgA E Amidinotransferase
IICHHMMA_00877 1.1e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
IICHHMMA_00878 1.6e-182 ykfD E Belongs to the ABC transporter superfamily
IICHHMMA_00879 1.9e-169 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IICHHMMA_00880 9.1e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IICHHMMA_00881 2.2e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IICHHMMA_00882 0.0 dppE E ABC transporter substrate-binding protein
IICHHMMA_00883 3.8e-190 dppD P Belongs to the ABC transporter superfamily
IICHHMMA_00884 1.1e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICHHMMA_00885 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICHHMMA_00886 6.5e-156 dppA E D-aminopeptidase
IICHHMMA_00887 2.7e-280 yubD P Major Facilitator Superfamily
IICHHMMA_00888 8.6e-206 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IICHHMMA_00890 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IICHHMMA_00891 5.2e-306 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IICHHMMA_00892 2e-177 mhqA E COG0346 Lactoylglutathione lyase and related lyases
IICHHMMA_00893 6.1e-241 steT E amino acid
IICHHMMA_00894 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
IICHHMMA_00895 5.8e-175 pit P phosphate transporter
IICHHMMA_00896 1.6e-132 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
IICHHMMA_00897 8.7e-23 spoIISB S Stage II sporulation protein SB
IICHHMMA_00898 1.6e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IICHHMMA_00899 1.3e-38 xhlB S SPP1 phage holin
IICHHMMA_00900 8.7e-38 xhlA S Haemolysin XhlA
IICHHMMA_00901 4e-136 xepA
IICHHMMA_00902 1e-27 xkdX
IICHHMMA_00904 1.9e-188
IICHHMMA_00905 1.2e-26
IICHHMMA_00906 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
IICHHMMA_00907 2.3e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IICHHMMA_00908 4.2e-58 xkdS S Protein of unknown function (DUF2634)
IICHHMMA_00909 2.5e-32 xkdR S Protein of unknown function (DUF2577)
IICHHMMA_00910 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
IICHHMMA_00911 5.6e-110 xkdP S Lysin motif
IICHHMMA_00912 1.4e-186 xkdO L Transglycosylase SLT domain
IICHHMMA_00913 3.4e-19
IICHHMMA_00914 4.9e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
IICHHMMA_00915 2e-74 xkdM S Phage tail tube protein
IICHHMMA_00916 7.7e-226 xkdK S Phage tail sheath C-terminal domain
IICHHMMA_00917 8.2e-15
IICHHMMA_00918 6.4e-57 xkdJ
IICHHMMA_00919 3.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
IICHHMMA_00920 5.5e-43 yqbH S Domain of unknown function (DUF3599)
IICHHMMA_00921 2e-46 yqbG S Protein of unknown function (DUF3199)
IICHHMMA_00922 4.6e-158 xkdG S Phage capsid family
IICHHMMA_00923 9.8e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
IICHHMMA_00924 2.3e-241 yqbA S portal protein
IICHHMMA_00925 7.9e-209 xtmB S phage terminase, large subunit
IICHHMMA_00926 1e-110 xtmA L phage terminase small subunit
IICHHMMA_00927 1.4e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IICHHMMA_00928 2e-10 yqaO S Phage-like element PBSX protein XtrA
IICHHMMA_00931 8.8e-150 xkdC L Bacterial dnaA protein
IICHHMMA_00933 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
IICHHMMA_00934 2.9e-110 xkdA E IrrE N-terminal-like domain
IICHHMMA_00936 9.7e-109 yjqB S phage-related replication protein
IICHHMMA_00937 4.7e-61 yjqA S Bacterial PH domain
IICHHMMA_00938 3.6e-166 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IICHHMMA_00940 4.9e-215 S response regulator aspartate phosphatase
IICHHMMA_00941 1.2e-77 yjoA S DinB family
IICHHMMA_00942 1.9e-130 MA20_18170 S membrane transporter protein
IICHHMMA_00943 4.6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
IICHHMMA_00944 1.1e-275 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
IICHHMMA_00945 1.4e-181 exuR K transcriptional
IICHHMMA_00946 6.7e-254 yjmB G symporter YjmB
IICHHMMA_00947 6.2e-276 uxaC 5.3.1.12 G glucuronate isomerase
IICHHMMA_00948 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
IICHHMMA_00949 7e-66 yjlC S Protein of unknown function (DUF1641)
IICHHMMA_00950 1.7e-90 yjlB S Cupin domain
IICHHMMA_00951 6.1e-177 yjlA EG Putative multidrug resistance efflux transporter
IICHHMMA_00952 4.6e-129 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
IICHHMMA_00953 2.1e-124 ybbM S transport system, permease component
IICHHMMA_00954 1.5e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IICHHMMA_00955 6.8e-29
IICHHMMA_00956 1e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IICHHMMA_00957 3.7e-224 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
IICHHMMA_00958 2.2e-91 yjgD S Protein of unknown function (DUF1641)
IICHHMMA_00959 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
IICHHMMA_00960 5.9e-100 yjgB S Domain of unknown function (DUF4309)
IICHHMMA_00961 3.3e-65 T PhoQ Sensor
IICHHMMA_00962 7.5e-22 yjfB S Putative motility protein
IICHHMMA_00964 8.1e-106 yhiD S MgtC SapB transporter
IICHHMMA_00965 6.5e-51 K helix_turn_helix multiple antibiotic resistance protein
IICHHMMA_00966 2e-34
IICHHMMA_00967 2.7e-123 5.4.2.6 S Haloacid dehalogenase-like hydrolase
IICHHMMA_00968 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
IICHHMMA_00969 4e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IICHHMMA_00970 3.4e-49 lacF 2.7.1.207 G phosphotransferase system
IICHHMMA_00971 2.8e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IICHHMMA_00972 1.5e-214 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IICHHMMA_00973 6.5e-187 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IICHHMMA_00974 7.3e-291 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IICHHMMA_00975 5e-220 ganA 3.2.1.89 G arabinogalactan
IICHHMMA_00976 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
IICHHMMA_00977 4.5e-250 yfjF EGP Belongs to the major facilitator superfamily
IICHHMMA_00978 1.6e-45 yjcS S Antibiotic biosynthesis monooxygenase
IICHHMMA_00979 1.7e-160 bla 3.5.2.6 V beta-lactamase
IICHHMMA_00981 3.3e-256 yobL S Bacterial EndoU nuclease
IICHHMMA_00982 7.7e-22
IICHHMMA_00983 2.8e-85
IICHHMMA_00984 1.9e-30
IICHHMMA_00986 1.7e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IICHHMMA_00987 3e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IICHHMMA_00988 1.8e-125 yjcH P COG2382 Enterochelin esterase and related enzymes
IICHHMMA_00989 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
IICHHMMA_00990 6.1e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IICHHMMA_00992 8e-35 K SpoVT / AbrB like domain
IICHHMMA_00993 6.4e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
IICHHMMA_00994 5.2e-125 S ABC-2 type transporter
IICHHMMA_00995 1.6e-140 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
IICHHMMA_00996 1.8e-35
IICHHMMA_00997 0.0 yjcD 3.6.4.12 L DNA helicase
IICHHMMA_00998 3.8e-38 spoVIF S Stage VI sporulation protein F
IICHHMMA_01002 5.6e-56 yjcA S Protein of unknown function (DUF1360)
IICHHMMA_01003 1.4e-52 cotV S Spore Coat Protein X and V domain
IICHHMMA_01004 6.8e-21 cotW
IICHHMMA_01005 6.6e-71 cotX S Spore Coat Protein X and V domain
IICHHMMA_01006 1.6e-90 cotY S Spore coat protein Z
IICHHMMA_01007 2.1e-76 cotZ S Spore coat protein
IICHHMMA_01008 2.5e-88 yjbX S Spore coat protein
IICHHMMA_01009 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IICHHMMA_01010 3.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IICHHMMA_01011 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IICHHMMA_01012 2.9e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IICHHMMA_01013 6.7e-30 thiS H Thiamine biosynthesis
IICHHMMA_01014 1.2e-208 thiO 1.4.3.19 E Glycine oxidase
IICHHMMA_01015 1.6e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
IICHHMMA_01016 9.9e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IICHHMMA_01017 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IICHHMMA_01018 6.8e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IICHHMMA_01019 5.4e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IICHHMMA_01020 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IICHHMMA_01021 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
IICHHMMA_01022 1.3e-60 yjbL S Belongs to the UPF0738 family
IICHHMMA_01023 1.1e-96 yjbK S protein conserved in bacteria
IICHHMMA_01024 4.2e-113 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IICHHMMA_01025 4.8e-72 yjbI S Bacterial-like globin
IICHHMMA_01026 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IICHHMMA_01027 1.7e-18
IICHHMMA_01028 0.0 pepF E oligoendopeptidase F
IICHHMMA_01029 4.9e-218 yjbF S Competence protein
IICHHMMA_01030 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IICHHMMA_01031 8.1e-109 yjbE P Integral membrane protein TerC family
IICHHMMA_01032 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IICHHMMA_01033 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IICHHMMA_01034 9.1e-228 S Putative glycosyl hydrolase domain
IICHHMMA_01035 1.1e-169 oppF E Belongs to the ABC transporter superfamily
IICHHMMA_01036 7.8e-202 oppD P Belongs to the ABC transporter superfamily
IICHHMMA_01037 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICHHMMA_01038 2.1e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICHHMMA_01039 0.0 oppA E ABC transporter substrate-binding protein
IICHHMMA_01040 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IICHHMMA_01041 1.6e-145 yjbA S Belongs to the UPF0736 family
IICHHMMA_01042 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICHHMMA_01043 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICHHMMA_01044 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
IICHHMMA_01045 5e-187 appF E Belongs to the ABC transporter superfamily
IICHHMMA_01046 2.2e-182 appD P Belongs to the ABC transporter superfamily
IICHHMMA_01047 5.6e-149 yjaZ O Zn-dependent protease
IICHHMMA_01048 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IICHHMMA_01049 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IICHHMMA_01050 1e-31 yjzB
IICHHMMA_01051 1.1e-26 comZ S ComZ
IICHHMMA_01052 2.7e-165 med S Transcriptional activator protein med
IICHHMMA_01053 1.4e-101 yjaV
IICHHMMA_01054 7.1e-138 yjaU I carboxylic ester hydrolase activity
IICHHMMA_01055 2.8e-22 yjzD S Protein of unknown function (DUF2929)
IICHHMMA_01056 1.2e-27 yjzC S YjzC-like protein
IICHHMMA_01057 1.3e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IICHHMMA_01058 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
IICHHMMA_01059 6.9e-203 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IICHHMMA_01060 2.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IICHHMMA_01061 1.2e-135 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
IICHHMMA_01062 1.3e-224 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IICHHMMA_01063 9.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IICHHMMA_01064 1.3e-88 norB G Major Facilitator Superfamily
IICHHMMA_01065 9.9e-269 yitY C D-arabinono-1,4-lactone oxidase
IICHHMMA_01066 4.9e-75 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IICHHMMA_01067 1.8e-50 yitW S metal-sulfur cluster biosynthetic enzyme
IICHHMMA_01068 6.9e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IICHHMMA_01069 5.1e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IICHHMMA_01070 3.5e-07
IICHHMMA_01071 4.4e-26 S Protein of unknown function (DUF3813)
IICHHMMA_01072 5.5e-80 ipi S Intracellular proteinase inhibitor
IICHHMMA_01073 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
IICHHMMA_01074 4.6e-157 yitS S protein conserved in bacteria
IICHHMMA_01076 1.4e-231 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
IICHHMMA_01077 2.6e-172 yufN S ABC transporter substrate-binding protein PnrA-like
IICHHMMA_01078 7.6e-160 cvfB S protein conserved in bacteria
IICHHMMA_01079 6.6e-55 yajQ S Belongs to the UPF0234 family
IICHHMMA_01080 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IICHHMMA_01081 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
IICHHMMA_01082 4.6e-69 mcbG S Pentapeptide repeats (9 copies)
IICHHMMA_01083 3e-193 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IICHHMMA_01084 7.8e-74 argO S Lysine exporter protein LysE YggA
IICHHMMA_01085 1.8e-84 yisT S DinB family
IICHHMMA_01086 2.2e-153 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
IICHHMMA_01087 1.2e-143 purR K helix_turn _helix lactose operon repressor
IICHHMMA_01088 5.9e-160 yisR K Transcriptional regulator
IICHHMMA_01089 1.5e-245 yisQ V Mate efflux family protein
IICHHMMA_01090 6.7e-128 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
IICHHMMA_01091 0.0 asnO 6.3.5.4 E Asparagine synthase
IICHHMMA_01092 3.8e-96 yisN S Protein of unknown function (DUF2777)
IICHHMMA_01093 3.2e-59 yisL S UPF0344 protein
IICHHMMA_01094 2.5e-169 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IICHHMMA_01095 4.8e-07 yisI S Spo0E like sporulation regulatory protein
IICHHMMA_01096 8.4e-34 gerPA S Spore germination protein
IICHHMMA_01097 1.8e-34 gerPB S cell differentiation
IICHHMMA_01098 4.1e-62 gerPC S Spore germination protein
IICHHMMA_01099 3.1e-23 gerPD S Spore germination protein
IICHHMMA_01100 8.1e-64 gerPE S Spore germination protein GerPE
IICHHMMA_01101 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
IICHHMMA_01102 1.3e-50 yisB V COG1403 Restriction endonuclease
IICHHMMA_01103 0.0 sbcC L COG0419 ATPase involved in DNA repair
IICHHMMA_01104 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IICHHMMA_01105 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IICHHMMA_01106 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
IICHHMMA_01107 1.1e-119 ydfS S Protein of unknown function (DUF421)
IICHHMMA_01108 2.1e-91 yhjR S Rubrerythrin
IICHHMMA_01109 4.2e-107 K QacR-like protein, C-terminal region
IICHHMMA_01110 6.6e-202 blt EGP Major facilitator Superfamily
IICHHMMA_01111 2.8e-181 abrB S membrane
IICHHMMA_01112 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
IICHHMMA_01113 1.1e-262 yhjG CH FAD binding domain
IICHHMMA_01114 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
IICHHMMA_01115 1.2e-109 yhjE S SNARE associated Golgi protein
IICHHMMA_01116 1.7e-60 yhjD
IICHHMMA_01117 3.1e-27 yhjC S Protein of unknown function (DUF3311)
IICHHMMA_01118 1.5e-267 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IICHHMMA_01119 2.1e-46 S Belongs to the UPF0145 family
IICHHMMA_01120 4.6e-42 yhjA S Excalibur calcium-binding domain
IICHHMMA_01121 8.7e-125 yrpD S Domain of unknown function, YrpD
IICHHMMA_01123 4.9e-63 frataxin S Domain of unknown function (DU1801)
IICHHMMA_01124 4.7e-66 frataxin S Domain of unknown function (DU1801)
IICHHMMA_01125 1.9e-109 comK K Competence transcription factor
IICHHMMA_01126 5.4e-31 yhzC S IDEAL
IICHHMMA_01127 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IICHHMMA_01128 1e-295 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
IICHHMMA_01129 3.1e-197 hemAT NT chemotaxis protein
IICHHMMA_01130 9.3e-90 bioY S BioY family
IICHHMMA_01131 4.7e-279 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IICHHMMA_01132 4.5e-197 vraB 2.3.1.9 I Belongs to the thiolase family
IICHHMMA_01133 2.6e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IICHHMMA_01134 1.6e-149 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IICHHMMA_01135 7.5e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
IICHHMMA_01136 1.2e-233 yhfN 3.4.24.84 O Peptidase M48
IICHHMMA_01137 4.8e-64 yhfM
IICHHMMA_01138 6.4e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IICHHMMA_01139 1.4e-108 yhfK GM NmrA-like family
IICHHMMA_01140 1.7e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
IICHHMMA_01141 4.9e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IICHHMMA_01142 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IICHHMMA_01143 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
IICHHMMA_01145 9.6e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IICHHMMA_01146 2.5e-245 yhgE S YhgE Pip N-terminal domain protein
IICHHMMA_01147 4.1e-101 yhgD K Transcriptional regulator
IICHHMMA_01148 2e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IICHHMMA_01149 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IICHHMMA_01150 2.8e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IICHHMMA_01151 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IICHHMMA_01152 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IICHHMMA_01153 1.4e-243 yhfA C membrane
IICHHMMA_01154 2.3e-223 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IICHHMMA_01155 2.3e-122 ecsC S EcsC protein family
IICHHMMA_01156 8.5e-221 ecsB U ABC transporter
IICHHMMA_01157 2.6e-135 ecsA V transporter (ATP-binding protein)
IICHHMMA_01158 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IICHHMMA_01159 1.9e-200 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IICHHMMA_01160 4.2e-76 trpP S Tryptophan transporter TrpP
IICHHMMA_01161 5.2e-18
IICHHMMA_01162 6.2e-39 yhaH S YtxH-like protein
IICHHMMA_01163 1.9e-112 hpr K Negative regulator of protease production and sporulation
IICHHMMA_01164 1.7e-54 yhaI S Protein of unknown function (DUF1878)
IICHHMMA_01165 7e-95 yhaK S Putative zincin peptidase
IICHHMMA_01166 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IICHHMMA_01167 1.1e-31 yhaL S Sporulation protein YhaL
IICHHMMA_01168 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
IICHHMMA_01169 0.0 yhaN L AAA domain
IICHHMMA_01170 5.2e-234 yhaO L DNA repair exonuclease
IICHHMMA_01171 5.2e-205 yhaP CP COG1668 ABC-type Na efflux pump, permease component
IICHHMMA_01172 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
IICHHMMA_01173 6.2e-14 S YhzD-like protein
IICHHMMA_01174 2.6e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
IICHHMMA_01176 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
IICHHMMA_01177 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
IICHHMMA_01178 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
IICHHMMA_01179 2.8e-290 hemZ H coproporphyrinogen III oxidase
IICHHMMA_01180 4.7e-157 yhaX S haloacid dehalogenase-like hydrolase
IICHHMMA_01181 5.4e-201 yhaZ L DNA alkylation repair enzyme
IICHHMMA_01182 1.5e-53 yheA S Belongs to the UPF0342 family
IICHHMMA_01183 3e-204 yheB S Belongs to the UPF0754 family
IICHHMMA_01184 5.8e-213 yheC HJ YheC/D like ATP-grasp
IICHHMMA_01185 5.1e-259 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
IICHHMMA_01186 1.7e-36 yheE S Family of unknown function (DUF5342)
IICHHMMA_01187 1.3e-28 sspB S spore protein
IICHHMMA_01189 1.6e-111 yheG GM NAD(P)H-binding
IICHHMMA_01190 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
IICHHMMA_01191 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
IICHHMMA_01193 6.2e-85 T universal stress protein
IICHHMMA_01194 4e-93 ymcC S Membrane
IICHHMMA_01195 3e-87 pksA K Transcriptional regulator
IICHHMMA_01196 5.3e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IICHHMMA_01197 1.3e-156 yheN G deacetylase
IICHHMMA_01198 5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IICHHMMA_01199 3.5e-205 yhdY M Mechanosensitive ion channel
IICHHMMA_01201 9.4e-127 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IICHHMMA_01202 1e-58 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IICHHMMA_01203 1.2e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IICHHMMA_01204 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
IICHHMMA_01205 5.2e-234 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IICHHMMA_01206 1.1e-225 yhdR 2.6.1.1 E Aminotransferase
IICHHMMA_01207 2.8e-70 cueR K transcriptional
IICHHMMA_01208 2.8e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IICHHMMA_01209 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IICHHMMA_01210 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
IICHHMMA_01211 1.9e-200 yhdL S Sigma factor regulator N-terminal
IICHHMMA_01212 8.1e-45 yhdK S Sigma-M inhibitor protein
IICHHMMA_01213 1.4e-197 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IICHHMMA_01214 1.2e-250 yhdG E amino acid
IICHHMMA_01215 1.9e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IICHHMMA_01216 1.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
IICHHMMA_01217 1.5e-163 citR K Transcriptional regulator
IICHHMMA_01218 2.2e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IICHHMMA_01219 1.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
IICHHMMA_01220 1e-270 ycgB S Stage V sporulation protein R
IICHHMMA_01221 4.2e-254 ygxB M Conserved TM helix
IICHHMMA_01222 5.6e-74 nsrR K Transcriptional regulator
IICHHMMA_01223 1.2e-213 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IICHHMMA_01224 1.1e-53 yhdC S Protein of unknown function (DUF3889)
IICHHMMA_01225 2.5e-39 yhdB S YhdB-like protein
IICHHMMA_01226 3.7e-88 azr 1.7.1.6 S NADPH-dependent FMN reductase
IICHHMMA_01227 1.3e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IICHHMMA_01228 9.4e-206 yhcY 2.7.13.3 T Histidine kinase
IICHHMMA_01229 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IICHHMMA_01230 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IICHHMMA_01231 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IICHHMMA_01232 1.7e-148 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
IICHHMMA_01233 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IICHHMMA_01234 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IICHHMMA_01235 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IICHHMMA_01236 4.9e-125 yhcW 5.4.2.6 S hydrolase
IICHHMMA_01237 9.9e-68 yhcV S COG0517 FOG CBS domain
IICHHMMA_01238 1.3e-69 yhcU S Family of unknown function (DUF5365)
IICHHMMA_01239 1.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IICHHMMA_01240 4e-107 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
IICHHMMA_01241 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
IICHHMMA_01242 8.4e-114 yhcQ M Spore coat protein
IICHHMMA_01243 2.2e-160 yhcP
IICHHMMA_01244 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IICHHMMA_01245 3.5e-52 yhcM
IICHHMMA_01246 1.1e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IICHHMMA_01247 1.1e-184 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
IICHHMMA_01248 2.2e-143 metQ M Belongs to the nlpA lipoprotein family
IICHHMMA_01249 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
IICHHMMA_01250 1.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IICHHMMA_01251 5.9e-166 yhcH V ABC transporter, ATP-binding protein
IICHHMMA_01252 6.7e-125 yhcG V ABC transporter, ATP-binding protein
IICHHMMA_01253 1.6e-61 yhcF K Transcriptional regulator
IICHHMMA_01254 2.1e-52
IICHHMMA_01255 3.8e-55 yhcC
IICHHMMA_01256 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
IICHHMMA_01257 8.4e-285 yhcA EGP Major facilitator Superfamily
IICHHMMA_01258 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
IICHHMMA_01259 4.6e-74 yhbI K DNA-binding transcription factor activity
IICHHMMA_01260 2.6e-214 yhbH S Belongs to the UPF0229 family
IICHHMMA_01261 0.0 prkA T Ser protein kinase
IICHHMMA_01263 3.6e-62 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
IICHHMMA_01264 6.4e-59 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
IICHHMMA_01265 1.3e-108 yhbD K Protein of unknown function (DUF4004)
IICHHMMA_01266 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IICHHMMA_01267 1.9e-172 yhbB S Putative amidase domain
IICHHMMA_01268 1.7e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IICHHMMA_01269 1.9e-107 yhzB S B3/4 domain
IICHHMMA_01271 4.8e-23 K Transcriptional regulator
IICHHMMA_01272 3e-81 ygaO
IICHHMMA_01273 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IICHHMMA_01274 3.2e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
IICHHMMA_01275 1.3e-143 ssuC P ABC transporter (permease)
IICHHMMA_01276 8.5e-179 ssuA M Sulfonate ABC transporter
IICHHMMA_01277 1.6e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IICHHMMA_01278 2.5e-180 S Amidohydrolase
IICHHMMA_01279 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IICHHMMA_01280 2.4e-133 oppF3 E Belongs to the ABC transporter superfamily
IICHHMMA_01281 1.3e-134 oppD3 P Belongs to the ABC transporter superfamily
IICHHMMA_01282 3.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICHHMMA_01283 2.7e-137 appB P Binding-protein-dependent transport system inner membrane component
IICHHMMA_01284 3.4e-231 oppA5 E PFAM extracellular solute-binding protein family 5
IICHHMMA_01286 1.4e-264 ygaK C Berberine and berberine like
IICHHMMA_01287 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IICHHMMA_01288 2.1e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
IICHHMMA_01289 4.2e-60 C Na+/H+ antiporter family
IICHHMMA_01293 1.6e-08
IICHHMMA_01301 7.8e-08
IICHHMMA_01306 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_01307 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
IICHHMMA_01308 1.7e-139 srfAD Q thioesterase
IICHHMMA_01309 2.3e-248 bamJ E Aminotransferase class I and II
IICHHMMA_01310 2.1e-128 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IICHHMMA_01311 1.7e-108 yczE S membrane
IICHHMMA_01312 5.3e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IICHHMMA_01313 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
IICHHMMA_01314 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IICHHMMA_01315 4.7e-157 bsdA K LysR substrate binding domain
IICHHMMA_01316 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IICHHMMA_01317 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IICHHMMA_01318 5.8e-38 bsdD 4.1.1.61 S response to toxic substance
IICHHMMA_01319 1.1e-75 yclD
IICHHMMA_01320 1.2e-269 dtpT E amino acid peptide transporter
IICHHMMA_01321 6.3e-278 yclG M Pectate lyase superfamily protein
IICHHMMA_01323 2.3e-293 gerKA EG Spore germination protein
IICHHMMA_01324 6.7e-234 gerKC S spore germination
IICHHMMA_01325 3.3e-195 gerKB F Spore germination protein
IICHHMMA_01326 1.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IICHHMMA_01327 5.7e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IICHHMMA_01328 1.3e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
IICHHMMA_01329 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
IICHHMMA_01330 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
IICHHMMA_01331 2.4e-217 yxeP 3.5.1.47 E hydrolase activity
IICHHMMA_01332 1.3e-251 yxeQ S MmgE/PrpD family
IICHHMMA_01333 3.9e-122 yclH P ABC transporter
IICHHMMA_01334 2.3e-233 yclI V ABC transporter (permease) YclI
IICHHMMA_01335 4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICHHMMA_01336 6.4e-260 T PhoQ Sensor
IICHHMMA_01337 9.5e-81 S aspartate phosphatase
IICHHMMA_01339 1.7e-249 lysC 2.7.2.4 E Belongs to the aspartokinase family
IICHHMMA_01340 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IICHHMMA_01341 1e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IICHHMMA_01342 6.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
IICHHMMA_01343 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
IICHHMMA_01344 5.6e-248 ycnB EGP Major facilitator Superfamily
IICHHMMA_01345 3e-151 ycnC K Transcriptional regulator
IICHHMMA_01346 8.8e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
IICHHMMA_01347 1e-44 ycnE S Monooxygenase
IICHHMMA_01348 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
IICHHMMA_01349 2e-261 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IICHHMMA_01350 3.1e-213 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IICHHMMA_01351 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IICHHMMA_01352 3.6e-149 glcU U Glucose uptake
IICHHMMA_01353 1.9e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IICHHMMA_01354 6e-98 ycnI S protein conserved in bacteria
IICHHMMA_01355 2.2e-296 ycnJ P protein, homolog of Cu resistance protein CopC
IICHHMMA_01356 6.2e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
IICHHMMA_01357 1.6e-55
IICHHMMA_01358 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
IICHHMMA_01359 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IICHHMMA_01360 2.1e-205 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
IICHHMMA_01361 3.9e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IICHHMMA_01363 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IICHHMMA_01364 1.3e-139 ycsF S Belongs to the UPF0271 (lamB) family
IICHHMMA_01365 7.4e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
IICHHMMA_01366 5.7e-149 ycsI S Belongs to the D-glutamate cyclase family
IICHHMMA_01367 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
IICHHMMA_01368 3.2e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
IICHHMMA_01369 1.1e-128 kipR K Transcriptional regulator
IICHHMMA_01370 9.3e-118 ycsK E anatomical structure formation involved in morphogenesis
IICHHMMA_01372 5.1e-56 yczJ S biosynthesis
IICHHMMA_01373 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
IICHHMMA_01374 1.7e-173 ydhF S Oxidoreductase
IICHHMMA_01375 0.0 mtlR K transcriptional regulator, MtlR
IICHHMMA_01376 3.2e-286 ydaB IQ acyl-CoA ligase
IICHHMMA_01377 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IICHHMMA_01378 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
IICHHMMA_01379 3.2e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IICHHMMA_01380 1.4e-77 ydaG 1.4.3.5 S general stress protein
IICHHMMA_01381 2.1e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IICHHMMA_01382 1.3e-47 ydzA EGP Major facilitator Superfamily
IICHHMMA_01383 4.3e-74 lrpC K Transcriptional regulator
IICHHMMA_01384 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IICHHMMA_01385 1.4e-198 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
IICHHMMA_01386 4.3e-147 ydaK T Diguanylate cyclase, GGDEF domain
IICHHMMA_01387 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
IICHHMMA_01388 7.2e-231 ydaM M Glycosyl transferase family group 2
IICHHMMA_01389 0.0 ydaN S Bacterial cellulose synthase subunit
IICHHMMA_01390 0.0 ydaO E amino acid
IICHHMMA_01391 9.8e-74 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IICHHMMA_01392 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IICHHMMA_01393 3.2e-12
IICHHMMA_01395 1.2e-72
IICHHMMA_01396 1.6e-97
IICHHMMA_01397 6.1e-39
IICHHMMA_01398 9.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
IICHHMMA_01400 1.9e-33 ydaT
IICHHMMA_01401 7.1e-71 yvaD S Family of unknown function (DUF5360)
IICHHMMA_01402 7e-54 yvaE P Small Multidrug Resistance protein
IICHHMMA_01403 9.8e-141 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
IICHHMMA_01404 1.4e-56 ydbB G Cupin domain
IICHHMMA_01405 1.7e-60 ydbC S Domain of unknown function (DUF4937
IICHHMMA_01406 1.2e-154 ydbD P Catalase
IICHHMMA_01407 2.5e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IICHHMMA_01408 5.5e-300 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IICHHMMA_01409 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
IICHHMMA_01410 2.9e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IICHHMMA_01411 2e-157 ydbI S AI-2E family transporter
IICHHMMA_01412 1.4e-170 ydbJ V ABC transporter, ATP-binding protein
IICHHMMA_01413 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IICHHMMA_01414 1.8e-51 ydbL
IICHHMMA_01415 1e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
IICHHMMA_01416 1.5e-10 S Fur-regulated basic protein B
IICHHMMA_01417 5.8e-09 S Fur-regulated basic protein A
IICHHMMA_01418 6.2e-120 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IICHHMMA_01419 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IICHHMMA_01420 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IICHHMMA_01421 5e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IICHHMMA_01422 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IICHHMMA_01423 1.3e-60 ydbS S Bacterial PH domain
IICHHMMA_01424 3.5e-261 ydbT S Membrane
IICHHMMA_01425 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
IICHHMMA_01426 1.5e-56 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IICHHMMA_01427 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
IICHHMMA_01428 5.8e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IICHHMMA_01429 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IICHHMMA_01430 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
IICHHMMA_01431 6.1e-146 rsbR T Positive regulator of sigma-B
IICHHMMA_01432 1.8e-57 rsbS T antagonist
IICHHMMA_01433 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IICHHMMA_01434 1.7e-187 rsbU 3.1.3.3 KT phosphatase
IICHHMMA_01435 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
IICHHMMA_01436 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IICHHMMA_01437 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IICHHMMA_01438 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
IICHHMMA_01439 0.0 yhgF K COG2183 Transcriptional accessory protein
IICHHMMA_01440 1.7e-14
IICHHMMA_01441 4.3e-58 ydcK S Belongs to the SprT family
IICHHMMA_01449 1.4e-08
IICHHMMA_01450 9.6e-149 S Serine aminopeptidase, S33
IICHHMMA_01451 9.8e-229 proP EGP Transporter
IICHHMMA_01452 1.5e-135 I esterase
IICHHMMA_01453 1.9e-47 ohrB O OsmC-like protein
IICHHMMA_01454 1.4e-48 ohrR K Transcriptional regulator
IICHHMMA_01455 2e-71 ywnA K Transcriptional regulator
IICHHMMA_01456 1.1e-110 ywnB S NAD(P)H-binding
IICHHMMA_01457 1.4e-30 cspL K Cold shock
IICHHMMA_01458 1e-78 carD K Transcription factor
IICHHMMA_01459 1.2e-118 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IICHHMMA_01460 1.4e-101 S Protein of unknown function (DUF2812)
IICHHMMA_01461 2.4e-50 K Transcriptional regulator PadR-like family
IICHHMMA_01462 5.6e-169 ybfA 3.4.15.5 K FR47-like protein
IICHHMMA_01463 5.6e-231 ybfB G COG0477 Permeases of the major facilitator superfamily
IICHHMMA_01464 2.3e-181 S Patatin-like phospholipase
IICHHMMA_01465 2e-77 S DinB superfamily
IICHHMMA_01466 1.1e-62 G Cupin domain
IICHHMMA_01468 4.3e-266 ygaK C COG0277 FAD FMN-containing dehydrogenases
IICHHMMA_01469 1.1e-41 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IICHHMMA_01470 6.4e-168 czcD P COG1230 Co Zn Cd efflux system component
IICHHMMA_01471 2.5e-197 trkA P Oxidoreductase
IICHHMMA_01472 6.2e-99 yrkC G Cupin domain
IICHHMMA_01473 4.2e-84 ykkA S Protein of unknown function (DUF664)
IICHHMMA_01474 2.4e-50 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
IICHHMMA_01475 8.7e-55 ydeH
IICHHMMA_01476 2.4e-83 F nucleoside 2-deoxyribosyltransferase
IICHHMMA_01477 1.4e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IICHHMMA_01478 4.6e-148 Q ubiE/COQ5 methyltransferase family
IICHHMMA_01479 3.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IICHHMMA_01480 4.9e-232 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IICHHMMA_01481 1.1e-165 S Sodium Bile acid symporter family
IICHHMMA_01482 1.4e-200 adhA 1.1.1.1 C alcohol dehydrogenase
IICHHMMA_01483 3.6e-67 yraB K helix_turn_helix, mercury resistance
IICHHMMA_01484 1.3e-219 mleN_2 C antiporter
IICHHMMA_01485 2e-258 K helix_turn_helix gluconate operon transcriptional repressor
IICHHMMA_01486 6.7e-113 paiB K Transcriptional regulator
IICHHMMA_01488 1.3e-173 ydeR EGP Major facilitator Superfamily
IICHHMMA_01489 3e-99 ydeS K Transcriptional regulator
IICHHMMA_01490 4.7e-48 yraD M Spore coat protein
IICHHMMA_01491 3.1e-24 yraE
IICHHMMA_01492 9.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IICHHMMA_01493 5.4e-62 yraF M Spore coat protein
IICHHMMA_01494 3.8e-35 yraG
IICHHMMA_01495 1.6e-214 ydfH 2.7.13.3 T Histidine kinase
IICHHMMA_01496 2.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IICHHMMA_01497 0.0 ydfJ S drug exporters of the RND superfamily
IICHHMMA_01498 5.2e-133 puuD S Peptidase C26
IICHHMMA_01499 1.1e-297 expZ S ABC transporter
IICHHMMA_01500 3e-98 ynaD J Acetyltransferase (GNAT) domain
IICHHMMA_01501 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
IICHHMMA_01502 3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
IICHHMMA_01503 1.8e-210 tcaB EGP Major facilitator Superfamily
IICHHMMA_01504 3.7e-224 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IICHHMMA_01505 1.3e-156 K Helix-turn-helix XRE-family like proteins
IICHHMMA_01506 3.8e-123 ydhB S membrane transporter protein
IICHHMMA_01507 2.2e-81 bltD 2.3.1.57 K FR47-like protein
IICHHMMA_01508 1.9e-147 bltR K helix_turn_helix, mercury resistance
IICHHMMA_01509 2.4e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IICHHMMA_01510 2.8e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
IICHHMMA_01511 8.8e-106 S Alpha/beta hydrolase family
IICHHMMA_01512 6.1e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
IICHHMMA_01513 2.4e-119 ydhC K FCD
IICHHMMA_01514 1.8e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IICHHMMA_01517 1.2e-260 pbpE V Beta-lactamase
IICHHMMA_01519 7.2e-98 ydhK M Protein of unknown function (DUF1541)
IICHHMMA_01520 2e-195 pbuE EGP Major facilitator Superfamily
IICHHMMA_01521 1.3e-133 ydhQ K UTRA
IICHHMMA_01522 9.9e-118 K FCD
IICHHMMA_01523 1.8e-215 yeaN P COG2807 Cyanate permease
IICHHMMA_01524 2.6e-49 sugE P Small Multidrug Resistance protein
IICHHMMA_01525 2.3e-51 ykkC P Small Multidrug Resistance protein
IICHHMMA_01526 1.3e-102 yvdT K Transcriptional regulator
IICHHMMA_01527 9.3e-297 yveA E amino acid
IICHHMMA_01528 3.5e-165 ydhU P Catalase
IICHHMMA_01529 1.3e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
IICHHMMA_01530 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
IICHHMMA_01531 9.2e-251 iolT EGP Major facilitator Superfamily
IICHHMMA_01534 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IICHHMMA_01535 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IICHHMMA_01536 8.1e-38 yaaB S Domain of unknown function (DUF370)
IICHHMMA_01537 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IICHHMMA_01538 2.4e-33 yaaA S S4 domain
IICHHMMA_01539 7.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IICHHMMA_01540 1.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IICHHMMA_01541 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IICHHMMA_01542 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IICHHMMA_01543 3.5e-109 jag S single-stranded nucleic acid binding R3H
IICHHMMA_01544 2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IICHHMMA_01545 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IICHHMMA_01546 7.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IICHHMMA_01547 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IICHHMMA_01548 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
IICHHMMA_01549 7.9e-149 spo0J K Belongs to the ParB family
IICHHMMA_01550 6.2e-111 yyaC S Sporulation protein YyaC
IICHHMMA_01551 8.1e-71 4.2.1.103 K FR47-like protein
IICHHMMA_01552 2.4e-176 yyaD S Membrane
IICHHMMA_01553 2.3e-33 yyzM S protein conserved in bacteria
IICHHMMA_01554 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IICHHMMA_01555 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IICHHMMA_01556 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
IICHHMMA_01557 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IICHHMMA_01558 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IICHHMMA_01559 9e-104 adaA 3.2.2.21 K Transcriptional regulator
IICHHMMA_01560 6.6e-22 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IICHHMMA_01561 1.6e-58 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IICHHMMA_01562 9.2e-141 xth 3.1.11.2 L exodeoxyribonuclease III
IICHHMMA_01563 1.3e-176 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
IICHHMMA_01564 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IICHHMMA_01565 2e-247 ydjK G Sugar (and other) transporter
IICHHMMA_01566 1.1e-161 yyaK S CAAX protease self-immunity
IICHHMMA_01567 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
IICHHMMA_01568 1.2e-21 yyaL O Highly conserved protein containing a thioredoxin domain
IICHHMMA_01569 7.9e-99 S Protein of unknown function (DUF554)
IICHHMMA_01570 6.7e-113 K Bacterial transcription activator, effector binding domain
IICHHMMA_01571 2.2e-133 ydfC EG EamA-like transporter family
IICHHMMA_01572 3.8e-252 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IICHHMMA_01573 8.6e-75 yjcF S Acetyltransferase (GNAT) domain
IICHHMMA_01574 1.6e-76 yybA 2.3.1.57 K transcriptional
IICHHMMA_01575 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IICHHMMA_01576 9.2e-69 ydgJ K Winged helix DNA-binding domain
IICHHMMA_01577 5.6e-115 drgA C nitroreductase
IICHHMMA_01578 2.2e-55 ypaA S Protein of unknown function (DUF1304)
IICHHMMA_01579 2.4e-159 G Major Facilitator Superfamily
IICHHMMA_01580 1.1e-73 dinB S PFAM DinB family protein
IICHHMMA_01581 2.2e-114 K FCD domain
IICHHMMA_01582 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
IICHHMMA_01583 2.2e-273 sacB 2.4.1.10 GH68 M levansucrase activity
IICHHMMA_01584 4.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IICHHMMA_01585 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
IICHHMMA_01586 2.8e-66 ydeP3 K Transcriptional regulator
IICHHMMA_01587 1.1e-84 cotF M Spore coat protein
IICHHMMA_01589 1.6e-158 yybS S membrane
IICHHMMA_01590 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IICHHMMA_01591 1.4e-72 rplI J binds to the 23S rRNA
IICHHMMA_01592 4.2e-121 KLT COG0515 Serine threonine protein kinase
IICHHMMA_01593 1.1e-121 S GlcNAc-PI de-N-acetylase
IICHHMMA_01594 4.4e-239 M Glycosyltransferase Family 4
IICHHMMA_01595 2.1e-232 S Carbamoyl-phosphate synthase L chain, ATP binding domain
IICHHMMA_01596 1.2e-202 S Ecdysteroid kinase
IICHHMMA_01597 1.2e-236 M Glycosyltransferase Family 4
IICHHMMA_01598 4.6e-17 yycC K YycC-like protein
IICHHMMA_01600 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
IICHHMMA_01601 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IICHHMMA_01602 9.4e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IICHHMMA_01603 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IICHHMMA_01608 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICHHMMA_01609 0.0 vicK 2.7.13.3 T Histidine kinase
IICHHMMA_01610 2.5e-261 yycH S protein conserved in bacteria
IICHHMMA_01611 1.1e-150 yycI S protein conserved in bacteria
IICHHMMA_01612 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IICHHMMA_01613 1.5e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IICHHMMA_01614 8.1e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICHHMMA_01615 1.2e-247 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
IICHHMMA_01616 4.6e-188 2.7.7.73, 2.7.7.80 H ThiF family
IICHHMMA_01617 1.1e-258
IICHHMMA_01618 3.4e-198 S Major Facilitator Superfamily
IICHHMMA_01619 9.1e-303 S ABC transporter
IICHHMMA_01620 2.9e-144 1.14.11.27 P peptidyl-arginine hydroxylation
IICHHMMA_01621 2.2e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IICHHMMA_01622 2.2e-42 sdpR K transcriptional
IICHHMMA_01623 8.5e-63 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IICHHMMA_01624 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
IICHHMMA_01625 1.1e-256 rocE E amino acid
IICHHMMA_01626 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
IICHHMMA_01627 2.2e-199 S Histidine kinase
IICHHMMA_01629 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
IICHHMMA_01630 8.7e-184 C oxidoreductases (related to aryl-alcohol dehydrogenases)
IICHHMMA_01631 1e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IICHHMMA_01632 2e-211 yycP
IICHHMMA_01635 7.9e-08 S YyzF-like protein
IICHHMMA_01636 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IICHHMMA_01637 1.2e-237 dgt 3.1.5.1 F dGTP triphosphohydrolase
IICHHMMA_01638 3.7e-96 cca 2.7.7.19, 2.7.7.72 J COG0617 tRNA nucleotidyltransferase poly(A) polymerase
IICHHMMA_01639 6e-21 S Restriction endonuclease
IICHHMMA_01640 8.1e-63 K ParB-like nuclease domain
IICHHMMA_01641 3.7e-177 S Fusaric acid resistance protein-like
IICHHMMA_01642 1.4e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IICHHMMA_01643 1.8e-86 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
IICHHMMA_01644 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IICHHMMA_01645 3.8e-151 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IICHHMMA_01646 1.3e-84 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IICHHMMA_01647 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
IICHHMMA_01648 9.6e-242 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
IICHHMMA_01649 7.2e-286 ahpF O Alkyl hydroperoxide reductase
IICHHMMA_01650 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
IICHHMMA_01651 1.4e-90 mrr V Mrr N-terminal domain
IICHHMMA_01652 6e-22 3.4.24.84 O metalloendopeptidase activity
IICHHMMA_01653 3.9e-249 L COG0210 Superfamily I DNA and RNA helicases
IICHHMMA_01654 3.2e-124 E Ring-cleavage extradiol dioxygenase
IICHHMMA_01655 3.8e-73 yxaI S membrane protein domain
IICHHMMA_01656 7.6e-203 EGP Major facilitator Superfamily
IICHHMMA_01657 2.3e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
IICHHMMA_01658 1.7e-64 S Family of unknown function (DUF5391)
IICHHMMA_01659 4e-141 S PQQ-like domain
IICHHMMA_01660 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IICHHMMA_01661 1.6e-213 yxbF K Bacterial regulatory proteins, tetR family
IICHHMMA_01662 1.6e-199 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
IICHHMMA_01663 1.2e-200 desK 2.7.13.3 T Histidine kinase
IICHHMMA_01664 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IICHHMMA_01665 1.5e-149 IQ Enoyl-(Acyl carrier protein) reductase
IICHHMMA_01667 0.0 htpG O Molecular chaperone. Has ATPase activity
IICHHMMA_01668 1.9e-245 csbC EGP Major facilitator Superfamily
IICHHMMA_01669 1.5e-172 iolS C Aldo keto reductase
IICHHMMA_01670 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
IICHHMMA_01671 4.8e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IICHHMMA_01672 3.9e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IICHHMMA_01673 1.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IICHHMMA_01674 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IICHHMMA_01675 3e-175 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IICHHMMA_01676 1.1e-229 iolF EGP Major facilitator Superfamily
IICHHMMA_01677 5.8e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IICHHMMA_01678 8e-165 iolH G Xylose isomerase-like TIM barrel
IICHHMMA_01679 1.9e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IICHHMMA_01680 8.6e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IICHHMMA_01681 1.7e-131 lanT 3.6.3.27 V TIGRFAM NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein
IICHHMMA_01682 3.8e-180 V Domain of unknown function (DUF4135)
IICHHMMA_01683 1.1e-37 4.1.1.36, 6.3.2.5 H Flavoprotein
IICHHMMA_01684 5.6e-14 KT Transcriptional regulatory protein, C terminal
IICHHMMA_01686 2.8e-126 S ABC-2 family transporter protein
IICHHMMA_01687 1.3e-131 S permease
IICHHMMA_01688 4.2e-164 bcrA V ABC transporter, ATP-binding protein
IICHHMMA_01689 1.7e-136 T Transcriptional regulator
IICHHMMA_01690 2.7e-266 T Histidine kinase
IICHHMMA_01691 9.3e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICHHMMA_01692 3.3e-175 T PhoQ Sensor
IICHHMMA_01693 3.6e-140 yxdL V ABC transporter, ATP-binding protein
IICHHMMA_01694 0.0 yxdM V ABC transporter (permease)
IICHHMMA_01695 1.3e-57 yxeA S Protein of unknown function (DUF1093)
IICHHMMA_01696 4.1e-178 fhuD P Periplasmic binding protein
IICHHMMA_01697 1.3e-34
IICHHMMA_01698 8.4e-23 yxeD
IICHHMMA_01702 1.2e-149 yidA S hydrolases of the HAD superfamily
IICHHMMA_01703 2.1e-171 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IICHHMMA_01704 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IICHHMMA_01705 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IICHHMMA_01706 2.2e-230 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
IICHHMMA_01707 4.4e-253 lysP E amino acid
IICHHMMA_01708 2.7e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IICHHMMA_01709 9.7e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
IICHHMMA_01710 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IICHHMMA_01711 1.1e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
IICHHMMA_01712 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IICHHMMA_01713 3.4e-274 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IICHHMMA_01714 1.9e-65 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IICHHMMA_01715 0.0 L HKD family nuclease
IICHHMMA_01716 2.4e-72 yxiE T Belongs to the universal stress protein A family
IICHHMMA_01717 1.2e-147 yxxF EG EamA-like transporter family
IICHHMMA_01718 8e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
IICHHMMA_01719 4.3e-68 yxiG
IICHHMMA_01723 1.1e-14 S YxiJ-like protein
IICHHMMA_01724 1.7e-22
IICHHMMA_01726 1.5e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IICHHMMA_01727 1.1e-220 yxiO S COG2270 Permeases of the major facilitator superfamily
IICHHMMA_01728 3.5e-149 licT K transcriptional antiterminator
IICHHMMA_01729 2e-140 exoK GH16 M licheninase activity
IICHHMMA_01730 1.4e-221 citH C Citrate transporter
IICHHMMA_01731 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
IICHHMMA_01733 1.5e-49 yxiS
IICHHMMA_01734 2.2e-69 T Domain of unknown function (DUF4163)
IICHHMMA_01735 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IICHHMMA_01736 3.1e-156 rlmA 2.1.1.187 Q Methyltransferase domain
IICHHMMA_01737 1.8e-217 yxjG 2.1.1.14 E Methionine synthase
IICHHMMA_01738 1.6e-85 yxjI S LURP-one-related
IICHHMMA_01741 2.3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IICHHMMA_01742 1.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IICHHMMA_01743 1.4e-86 yxkC S Domain of unknown function (DUF4352)
IICHHMMA_01744 8.3e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IICHHMMA_01745 2.3e-162 lrp QT PucR C-terminal helix-turn-helix domain
IICHHMMA_01746 3.5e-205 msmK P Belongs to the ABC transporter superfamily
IICHHMMA_01747 9.6e-155 yxkH G Polysaccharide deacetylase
IICHHMMA_01748 1e-214 cimH C COG3493 Na citrate symporter
IICHHMMA_01749 4.5e-266 cydA 1.10.3.14 C oxidase, subunit
IICHHMMA_01750 2.5e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
IICHHMMA_01751 0.0 cydD V ATP-binding
IICHHMMA_01752 1.5e-292 cydD V ATP-binding protein
IICHHMMA_01753 6.1e-154 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IICHHMMA_01754 7.9e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
IICHHMMA_01755 1.4e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IICHHMMA_01756 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IICHHMMA_01757 5.4e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
IICHHMMA_01758 6.2e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
IICHHMMA_01759 8.2e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
IICHHMMA_01760 2.1e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IICHHMMA_01761 1.2e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IICHHMMA_01762 1.7e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
IICHHMMA_01763 5.8e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
IICHHMMA_01764 8.5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IICHHMMA_01765 1.7e-57 arsR K transcriptional
IICHHMMA_01766 3.4e-166 cbrA3 P Periplasmic binding protein
IICHHMMA_01767 1e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IICHHMMA_01768 4.7e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IICHHMMA_01769 3.5e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IICHHMMA_01770 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
IICHHMMA_01771 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
IICHHMMA_01772 5.7e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IICHHMMA_01773 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
IICHHMMA_01774 4.6e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IICHHMMA_01775 9.3e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IICHHMMA_01776 1.9e-193 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IICHHMMA_01777 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_01778 3.7e-229 dltB M membrane protein involved in D-alanine export
IICHHMMA_01779 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_01780 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
IICHHMMA_01781 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
IICHHMMA_01782 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
IICHHMMA_01783 2e-160 gspA M General stress
IICHHMMA_01784 1.1e-258 epr 3.4.21.62 O Belongs to the peptidase S8 family
IICHHMMA_01785 5.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IICHHMMA_01786 7.6e-67 ywbC 4.4.1.5 E glyoxalase
IICHHMMA_01787 1.2e-222 ywbD 2.1.1.191 J Methyltransferase
IICHHMMA_01788 8.1e-137 mta K transcriptional
IICHHMMA_01789 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
IICHHMMA_01790 1.5e-110 ywbG M effector of murein hydrolase
IICHHMMA_01791 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IICHHMMA_01792 8.2e-152 ywbI K Transcriptional regulator
IICHHMMA_01793 3.7e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IICHHMMA_01794 3.8e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IICHHMMA_01795 1.3e-240 ywbN P Dyp-type peroxidase family protein
IICHHMMA_01796 1.1e-109 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IICHHMMA_01797 7.7e-131 S Streptomycin biosynthesis protein StrF
IICHHMMA_01798 5.6e-129 H Methionine biosynthesis protein MetW
IICHHMMA_01800 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
IICHHMMA_01801 5.1e-61 gtcA S GtrA-like protein
IICHHMMA_01802 1.9e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IICHHMMA_01803 8.4e-27 ywzA S membrane
IICHHMMA_01804 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IICHHMMA_01805 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IICHHMMA_01806 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IICHHMMA_01807 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IICHHMMA_01808 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
IICHHMMA_01809 3.1e-75 ysnE K acetyltransferase
IICHHMMA_01810 8e-208 rodA D Belongs to the SEDS family
IICHHMMA_01811 5.7e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
IICHHMMA_01812 5.2e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IICHHMMA_01813 0.0 vpr O Belongs to the peptidase S8 family
IICHHMMA_01815 2.8e-151 sacT K transcriptional antiterminator
IICHHMMA_01816 3.8e-249 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IICHHMMA_01817 7.8e-282 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
IICHHMMA_01818 7.4e-20 ywdA
IICHHMMA_01819 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IICHHMMA_01820 6.3e-57 pex K Transcriptional regulator PadR-like family
IICHHMMA_01821 4.5e-88 ywdD
IICHHMMA_01823 5.2e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
IICHHMMA_01824 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IICHHMMA_01825 5.7e-39 ywdI S Family of unknown function (DUF5327)
IICHHMMA_01826 5.4e-229 ywdJ F Xanthine uracil
IICHHMMA_01827 4.2e-46 ywdK S small membrane protein
IICHHMMA_01828 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IICHHMMA_01829 1.7e-142 spsA M Spore Coat
IICHHMMA_01830 4.5e-274 spsB M Capsule polysaccharide biosynthesis protein
IICHHMMA_01831 2.6e-219 spsC E Belongs to the DegT DnrJ EryC1 family
IICHHMMA_01832 3e-156 spsD 2.3.1.210 K Spore Coat
IICHHMMA_01833 3.8e-215 spsE 2.5.1.56 M acid synthase
IICHHMMA_01834 1.3e-131 spsF M Spore Coat
IICHHMMA_01835 2.6e-175 spsG M Spore Coat
IICHHMMA_01836 7.9e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IICHHMMA_01837 6.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IICHHMMA_01838 1.2e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IICHHMMA_01839 3.5e-87 spsL 5.1.3.13 M Spore Coat
IICHHMMA_01840 1.9e-59
IICHHMMA_01841 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IICHHMMA_01842 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IICHHMMA_01843 0.0 rocB E arginine degradation protein
IICHHMMA_01844 2.7e-258 lysP E amino acid
IICHHMMA_01845 2.2e-205 tcaB EGP Major facilitator Superfamily
IICHHMMA_01846 2.1e-222 ywfA EGP Major facilitator Superfamily
IICHHMMA_01847 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IICHHMMA_01848 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IICHHMMA_01849 1.9e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IICHHMMA_01850 6.3e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IICHHMMA_01851 4e-207 bacE EGP Major facilitator Superfamily
IICHHMMA_01852 2.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
IICHHMMA_01853 6.3e-140 IQ Enoyl-(Acyl carrier protein) reductase
IICHHMMA_01854 2.5e-146 ywfI C May function as heme-dependent peroxidase
IICHHMMA_01855 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
IICHHMMA_01856 1e-155 MA20_14895 S Conserved hypothetical protein 698
IICHHMMA_01857 3e-162 cysL K Transcriptional regulator
IICHHMMA_01858 7.2e-158 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IICHHMMA_01860 3.7e-176
IICHHMMA_01863 9.4e-167 yhcI S ABC transporter (permease)
IICHHMMA_01864 1.6e-163 V ABC transporter, ATP-binding protein
IICHHMMA_01865 1.1e-93 S membrane
IICHHMMA_01866 9.7e-52 padR K PadR family transcriptional regulator
IICHHMMA_01867 6.6e-110 rsfA_1
IICHHMMA_01868 6.9e-36 ywzC S Belongs to the UPF0741 family
IICHHMMA_01869 5.6e-255 ywfO S COG1078 HD superfamily phosphohydrolases
IICHHMMA_01870 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
IICHHMMA_01871 1.5e-245 yhdG_1 E C-terminus of AA_permease
IICHHMMA_01872 4.9e-67 ywhA K Transcriptional regulator
IICHHMMA_01873 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
IICHHMMA_01874 2.8e-117 ywhC S Peptidase family M50
IICHHMMA_01875 6.4e-93 ywhD S YwhD family
IICHHMMA_01876 1.5e-79
IICHHMMA_01877 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IICHHMMA_01878 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IICHHMMA_01879 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
IICHHMMA_01882 7.5e-75 CP Membrane
IICHHMMA_01884 1.6e-31
IICHHMMA_01885 9.7e-29 ydcG K sequence-specific DNA binding
IICHHMMA_01887 6.4e-77 S aspartate phosphatase
IICHHMMA_01888 2.3e-43 ywiB S protein conserved in bacteria
IICHHMMA_01889 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IICHHMMA_01890 2.4e-212 narK P COG2223 Nitrate nitrite transporter
IICHHMMA_01891 6.5e-128 fnr K helix_turn_helix, cAMP Regulatory protein
IICHHMMA_01892 6.3e-139 ywiC S YwiC-like protein
IICHHMMA_01893 8.5e-84 arfM T cyclic nucleotide binding
IICHHMMA_01894 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IICHHMMA_01895 3.1e-294 narH 1.7.5.1 C Nitrate reductase, beta
IICHHMMA_01896 4.8e-94 narJ 1.7.5.1 C nitrate reductase
IICHHMMA_01897 7.2e-121 narI 1.7.5.1 C nitrate reductase, gamma
IICHHMMA_01898 4e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IICHHMMA_01899 1.5e-294 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IICHHMMA_01900 0.0 ywjA V ABC transporter
IICHHMMA_01901 4.2e-43 ywjC
IICHHMMA_01902 2e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IICHHMMA_01903 1.5e-214 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IICHHMMA_01904 0.0 fadF C COG0247 Fe-S oxidoreductase
IICHHMMA_01905 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IICHHMMA_01906 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IICHHMMA_01907 4.2e-92 ywjG S Domain of unknown function (DUF2529)
IICHHMMA_01908 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
IICHHMMA_01909 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
IICHHMMA_01910 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IICHHMMA_01911 7.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IICHHMMA_01912 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
IICHHMMA_01913 1.1e-32 rpmE J Binds the 23S rRNA
IICHHMMA_01914 4.6e-103 tdk 2.7.1.21 F thymidine kinase
IICHHMMA_01915 0.0 sfcA 1.1.1.38 C malic enzyme
IICHHMMA_01916 6.8e-157 ywkB S Membrane transport protein
IICHHMMA_01917 7.4e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IICHHMMA_01918 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IICHHMMA_01919 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IICHHMMA_01920 2.3e-156 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IICHHMMA_01922 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
IICHHMMA_01923 2.6e-118 spoIIR S stage II sporulation protein R
IICHHMMA_01924 3.9e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
IICHHMMA_01925 4.3e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IICHHMMA_01926 1.3e-83 mntP P Probably functions as a manganese efflux pump
IICHHMMA_01927 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IICHHMMA_01928 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
IICHHMMA_01929 3.2e-95 ywlG S Belongs to the UPF0340 family
IICHHMMA_01930 2.8e-235 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IICHHMMA_01931 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IICHHMMA_01932 2.1e-61 atpI S ATP synthase
IICHHMMA_01933 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
IICHHMMA_01934 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IICHHMMA_01935 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IICHHMMA_01936 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IICHHMMA_01937 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IICHHMMA_01938 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IICHHMMA_01939 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IICHHMMA_01940 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IICHHMMA_01941 8.7e-89 ywmA
IICHHMMA_01942 4.8e-32 ywzB S membrane
IICHHMMA_01943 2.2e-134 ywmB S TATA-box binding
IICHHMMA_01944 1.4e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IICHHMMA_01945 9.5e-189 spoIID D Stage II sporulation protein D
IICHHMMA_01946 5.1e-114 ywmC S protein containing a von Willebrand factor type A (vWA) domain
IICHHMMA_01947 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
IICHHMMA_01949 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IICHHMMA_01950 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IICHHMMA_01951 2.2e-93 S response regulator aspartate phosphatase
IICHHMMA_01952 3.6e-82 ywmF S Peptidase M50
IICHHMMA_01953 1.4e-10 csbD K CsbD-like
IICHHMMA_01954 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IICHHMMA_01955 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IICHHMMA_01956 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IICHHMMA_01957 6.1e-67 ywnA K Transcriptional regulator
IICHHMMA_01959 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
IICHHMMA_01960 2.4e-52 ywnC S Family of unknown function (DUF5362)
IICHHMMA_01961 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IICHHMMA_01962 4.2e-69 ywnF S Family of unknown function (DUF5392)
IICHHMMA_01963 1.2e-10 ywnC S Family of unknown function (DUF5362)
IICHHMMA_01964 4.9e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
IICHHMMA_01965 1.4e-121 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
IICHHMMA_01966 5.4e-62 ywnJ S VanZ like family
IICHHMMA_01968 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
IICHHMMA_01969 3.9e-207 ftsW D Belongs to the SEDS family
IICHHMMA_01970 2e-58 nrgB K Belongs to the P(II) protein family
IICHHMMA_01971 2.5e-228 amt P Ammonium transporter
IICHHMMA_01972 6.3e-102 phzA Q Isochorismatase family
IICHHMMA_01973 2.7e-244 ywoD EGP Major facilitator superfamily
IICHHMMA_01974 4.2e-275 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
IICHHMMA_01975 1.4e-212 ywoG EGP Major facilitator Superfamily
IICHHMMA_01976 7.2e-71 ywoH K transcriptional
IICHHMMA_01977 1.8e-44 spoIIID K Stage III sporulation protein D
IICHHMMA_01978 2.7e-180 mbl D Rod shape-determining protein
IICHHMMA_01979 3.2e-128 flhO N flagellar basal body
IICHHMMA_01980 7e-142 flhP N flagellar basal body
IICHHMMA_01981 1.5e-197 S aspartate phosphatase
IICHHMMA_01982 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IICHHMMA_01983 1.1e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IICHHMMA_01984 2.5e-68 ywpF S YwpF-like protein
IICHHMMA_01985 4e-62 ywpG
IICHHMMA_01986 3.7e-57 ssbB L Single-stranded DNA-binding protein
IICHHMMA_01987 7.5e-138 glcR K DeoR C terminal sensor domain
IICHHMMA_01988 6.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
IICHHMMA_01989 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IICHHMMA_01990 1.2e-307 ywqB S SWIM zinc finger
IICHHMMA_01991 1.3e-14
IICHHMMA_01992 4.9e-110 ywqC M biosynthesis protein
IICHHMMA_01993 9.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
IICHHMMA_01994 1.6e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
IICHHMMA_01995 4.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IICHHMMA_01996 2.6e-146 ywqG S Domain of unknown function (DUF1963)
IICHHMMA_01998 1.4e-21 S Domain of unknown function (DUF5082)
IICHHMMA_01999 4.3e-37 ywqI S Family of unknown function (DUF5344)
IICHHMMA_02000 3.7e-302 ywqJ S Pre-toxin TG
IICHHMMA_02001 2.6e-49
IICHHMMA_02002 2.5e-85
IICHHMMA_02003 1.8e-133 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IICHHMMA_02004 3.1e-156 K Transcriptional regulator
IICHHMMA_02005 5.7e-92 ywqN S NAD(P)H-dependent
IICHHMMA_02007 1.4e-87 ywrA P COG2059 Chromate transport protein ChrA
IICHHMMA_02008 5e-102 ywrB P Chromate transporter
IICHHMMA_02009 3.2e-83 ywrC K Transcriptional regulator
IICHHMMA_02010 5.9e-299 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IICHHMMA_02012 4.3e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IICHHMMA_02013 2.9e-09
IICHHMMA_02014 3.2e-211 cotH M Spore Coat
IICHHMMA_02015 6e-131 cotB
IICHHMMA_02016 4.4e-126 ywrJ
IICHHMMA_02017 6.4e-238 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IICHHMMA_02018 2.6e-166 alsR K LysR substrate binding domain
IICHHMMA_02019 2.6e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IICHHMMA_02020 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
IICHHMMA_02021 9e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
IICHHMMA_02022 1.5e-89 batE T Sh3 type 3 domain protein
IICHHMMA_02023 2e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
IICHHMMA_02024 1.1e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
IICHHMMA_02025 4.2e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IICHHMMA_02026 5.3e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IICHHMMA_02027 1e-154 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IICHHMMA_02028 1.6e-177 rbsR K transcriptional
IICHHMMA_02029 9.1e-201 gerKC S Spore germination B3/ GerAC like, C-terminal
IICHHMMA_02030 1.8e-190 gerKB E Spore germination protein
IICHHMMA_02031 1e-183 gerKA EG Spore germination protein
IICHHMMA_02032 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
IICHHMMA_02033 2.3e-70 pgsC S biosynthesis protein
IICHHMMA_02034 3.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IICHHMMA_02035 1.3e-20 ywtC
IICHHMMA_02036 6.6e-237 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IICHHMMA_02037 2.5e-23 yttA 2.7.13.3 S Pfam Transposase IS66
IICHHMMA_02039 9.4e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
IICHHMMA_02040 7.2e-178 ywtF K Transcriptional regulator
IICHHMMA_02041 4.6e-247 ywtG EGP Major facilitator Superfamily
IICHHMMA_02042 1.7e-265 GT2,GT4 J Glycosyl transferase family 2
IICHHMMA_02043 6.3e-210 gerAC S Spore germination protein
IICHHMMA_02044 4.3e-195 gerBB E Spore germination protein
IICHHMMA_02045 2.8e-263 gerBA EG Spore germination protein
IICHHMMA_02046 1e-184 pmi 5.3.1.8 G mannose-6-phosphate isomerase
IICHHMMA_02047 4.7e-240 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IICHHMMA_02048 3.4e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IICHHMMA_02049 5e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IICHHMMA_02050 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
IICHHMMA_02051 2.4e-43 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
IICHHMMA_02052 2.2e-188 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
IICHHMMA_02053 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IICHHMMA_02054 7.5e-136 tagG GM Transport permease protein
IICHHMMA_02055 1.5e-182 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IICHHMMA_02056 3.7e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IICHHMMA_02057 1.3e-183 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IICHHMMA_02058 2.8e-137 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IICHHMMA_02059 2.6e-30
IICHHMMA_02060 8.7e-306 lytB 3.5.1.28 D Stage II sporulation protein
IICHHMMA_02061 5.9e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IICHHMMA_02062 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IICHHMMA_02063 2.5e-256 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IICHHMMA_02064 3.7e-221 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
IICHHMMA_02065 1.3e-249 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IICHHMMA_02066 1.4e-254 tuaE M Teichuronic acid biosynthesis protein
IICHHMMA_02067 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
IICHHMMA_02068 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
IICHHMMA_02069 3.5e-235 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
IICHHMMA_02070 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IICHHMMA_02071 3.7e-165 yvhJ K Transcriptional regulator
IICHHMMA_02072 1.4e-118 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
IICHHMMA_02073 3.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IICHHMMA_02074 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IICHHMMA_02075 1.4e-158 degV S protein conserved in bacteria
IICHHMMA_02076 5.4e-256 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IICHHMMA_02077 4.4e-43 comFB S Late competence development protein ComFB
IICHHMMA_02078 2.9e-76 comFC S Phosphoribosyl transferase domain
IICHHMMA_02079 7.8e-73 yvyF S flagellar protein
IICHHMMA_02080 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
IICHHMMA_02081 8.9e-81 flgN NOU FlgN protein
IICHHMMA_02082 1.8e-273 flgK N flagellar hook-associated protein
IICHHMMA_02083 2.3e-162 flgL N Belongs to the bacterial flagellin family
IICHHMMA_02084 8.9e-80 yviE
IICHHMMA_02085 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IICHHMMA_02086 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IICHHMMA_02087 2.1e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IICHHMMA_02088 5.2e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IICHHMMA_02089 3e-66 fliS N flagellar protein FliS
IICHHMMA_02090 5.9e-10 fliT S bacterial-type flagellum organization
IICHHMMA_02091 6.8e-68
IICHHMMA_02092 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IICHHMMA_02093 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IICHHMMA_02094 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IICHHMMA_02095 3.9e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
IICHHMMA_02096 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
IICHHMMA_02097 2.3e-122 ftsE D cell division ATP-binding protein FtsE
IICHHMMA_02098 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IICHHMMA_02099 9.5e-224 ywoF P Right handed beta helix region
IICHHMMA_02100 8.2e-252 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
IICHHMMA_02101 1.5e-55 swrA S Swarming motility protein
IICHHMMA_02102 2.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IICHHMMA_02103 3.3e-176 S Psort location CytoplasmicMembrane, score
IICHHMMA_02104 3.6e-42 bacT Q Thioesterase domain
IICHHMMA_02105 3.3e-226 yvkA EGP Major facilitator Superfamily
IICHHMMA_02106 2e-109 yvkB K Transcriptional regulator
IICHHMMA_02107 0.0 yvkC 2.7.9.2 GT Phosphotransferase
IICHHMMA_02108 7.6e-33 csbA S protein conserved in bacteria
IICHHMMA_02109 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IICHHMMA_02110 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IICHHMMA_02111 2.2e-32 yvkN
IICHHMMA_02112 6.1e-49 yvlA
IICHHMMA_02113 1e-164 yvlB S Putative adhesin
IICHHMMA_02114 9.6e-26 pspB KT PspC domain
IICHHMMA_02115 1.5e-40 yvlD S Membrane
IICHHMMA_02116 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
IICHHMMA_02117 4.4e-103 yxaF K Transcriptional regulator
IICHHMMA_02118 2.6e-132 yvoA K transcriptional
IICHHMMA_02119 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IICHHMMA_02120 1.2e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IICHHMMA_02121 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IICHHMMA_02122 2.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IICHHMMA_02123 2e-112 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IICHHMMA_02124 1.9e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
IICHHMMA_02125 4.5e-137 yvpB NU protein conserved in bacteria
IICHHMMA_02126 1.5e-206 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IICHHMMA_02127 5.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IICHHMMA_02128 1e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IICHHMMA_02129 3e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IICHHMMA_02130 9.6e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IICHHMMA_02131 6e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IICHHMMA_02132 4.9e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IICHHMMA_02133 5.8e-109 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
IICHHMMA_02134 0.0 msbA2 3.6.3.44 V ABC transporter
IICHHMMA_02135 7.2e-59
IICHHMMA_02136 2.1e-120 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICHHMMA_02137 1.4e-190 sasA T Histidine kinase
IICHHMMA_02138 9.3e-275 S COG0457 FOG TPR repeat
IICHHMMA_02139 1e-121 usp CBM50 M protein conserved in bacteria
IICHHMMA_02140 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IICHHMMA_02141 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IICHHMMA_02142 2.2e-165 rapZ S Displays ATPase and GTPase activities
IICHHMMA_02143 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IICHHMMA_02144 4.1e-170 whiA K May be required for sporulation
IICHHMMA_02145 4.7e-36 crh G Phosphocarrier protein Chr
IICHHMMA_02146 1.3e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
IICHHMMA_02147 4.4e-21
IICHHMMA_02148 7.8e-28 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
IICHHMMA_02149 4.8e-79 M Ribonuclease
IICHHMMA_02150 6.6e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IICHHMMA_02151 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IICHHMMA_02152 7.3e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
IICHHMMA_02153 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
IICHHMMA_02154 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
IICHHMMA_02155 1.4e-248 EGP Sugar (and other) transporter
IICHHMMA_02156 8.7e-212 yraM S PrpF protein
IICHHMMA_02157 6.7e-164 yraN K Transcriptional regulator
IICHHMMA_02158 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IICHHMMA_02159 1.2e-180 scrR K transcriptional
IICHHMMA_02160 1.1e-218 rafB P LacY proton/sugar symporter
IICHHMMA_02161 6.9e-294 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
IICHHMMA_02163 1.2e-33
IICHHMMA_02164 4.6e-242 I Pfam Lipase (class 3)
IICHHMMA_02165 3.4e-18 S Protein of unknown function (DUF1433)
IICHHMMA_02167 7.3e-22 S Protein of unknown function (DUF1433)
IICHHMMA_02168 2.4e-16 S Protein of unknown function (DUF1433)
IICHHMMA_02169 2.9e-32 I Pfam Lipase (class 3)
IICHHMMA_02170 8.5e-38 S Protein of unknown function (DUF1433)
IICHHMMA_02171 2.7e-16 S Protein of unknown function (DUF1433)
IICHHMMA_02172 1.6e-93 padC Q Phenolic acid decarboxylase
IICHHMMA_02173 1.9e-89 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IICHHMMA_02174 4.4e-112 yyaS S Membrane
IICHHMMA_02175 4.8e-96 ywjB H RibD C-terminal domain
IICHHMMA_02177 2.9e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
IICHHMMA_02178 5.7e-77 slr K transcriptional
IICHHMMA_02179 1.2e-118 ywqC M biosynthesis protein
IICHHMMA_02180 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
IICHHMMA_02181 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
IICHHMMA_02182 5.7e-219 epsD GT4 M Glycosyl transferase 4-like
IICHHMMA_02183 1.5e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IICHHMMA_02184 3.9e-212 epsF GT4 M Glycosyl transferases group 1
IICHHMMA_02185 1.5e-203 epsG S EpsG family
IICHHMMA_02186 4.1e-192 epsH GT2 S Glycosyltransferase like family 2
IICHHMMA_02187 1.1e-203 epsI GM pyruvyl transferase
IICHHMMA_02188 9.8e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
IICHHMMA_02189 7e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IICHHMMA_02190 1.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IICHHMMA_02191 2.4e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
IICHHMMA_02192 6.9e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IICHHMMA_02193 2.9e-187 yvfF GM Exopolysaccharide biosynthesis protein
IICHHMMA_02194 2.7e-32 yvfG S YvfG protein
IICHHMMA_02195 2.3e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IICHHMMA_02196 4.6e-302 yvfH C L-lactate permease
IICHHMMA_02197 3e-120 yvfI K COG2186 Transcriptional regulators
IICHHMMA_02198 2.7e-219 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IICHHMMA_02199 7.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IICHHMMA_02200 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IICHHMMA_02201 4.1e-130 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IICHHMMA_02202 3.3e-210 gntP EG COG2610 H gluconate symporter and related permeases
IICHHMMA_02203 9.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
IICHHMMA_02204 1.5e-150 ybbH_1 K RpiR family transcriptional regulator
IICHHMMA_02205 2.8e-165 3.1.3.104 S hydrolases of the HAD superfamily
IICHHMMA_02206 3.2e-113 yyaS S Membrane
IICHHMMA_02207 7.3e-183 purR7 5.1.1.1 K Transcriptional regulator
IICHHMMA_02208 2.5e-258
IICHHMMA_02209 3.8e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
IICHHMMA_02210 1.5e-156 yvbV EG EamA-like transporter family
IICHHMMA_02211 2.6e-155 yvbU K Transcriptional regulator
IICHHMMA_02213 2.1e-188 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IICHHMMA_02214 3.7e-41
IICHHMMA_02215 1.4e-203 araR K transcriptional
IICHHMMA_02216 7.4e-253 araE EGP Major facilitator Superfamily
IICHHMMA_02218 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IICHHMMA_02219 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IICHHMMA_02220 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IICHHMMA_02221 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IICHHMMA_02222 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
IICHHMMA_02223 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IICHHMMA_02224 2.6e-236 ywaD 3.4.11.10, 3.4.11.6 S PA domain
IICHHMMA_02225 8.9e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IICHHMMA_02226 2.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IICHHMMA_02227 6.8e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
IICHHMMA_02228 1.7e-219 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IICHHMMA_02229 2.3e-146 M Protein involved in cellulose biosynthesis
IICHHMMA_02230 3.1e-141 C WbqC-like protein family
IICHHMMA_02231 1.7e-122 S GlcNAc-PI de-N-acetylase
IICHHMMA_02232 3.3e-177
IICHHMMA_02233 3.1e-210 EGP Major facilitator Superfamily
IICHHMMA_02234 2.1e-79 yvbK 3.1.3.25 K acetyltransferase
IICHHMMA_02235 0.0 tcaA S response to antibiotic
IICHHMMA_02236 6.4e-120 exoY M Membrane
IICHHMMA_02237 2.9e-103 yvbG U UPF0056 membrane protein
IICHHMMA_02238 1.2e-97 yvbF K Belongs to the GbsR family
IICHHMMA_02239 2.6e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IICHHMMA_02240 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IICHHMMA_02241 3.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IICHHMMA_02242 1.8e-108 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IICHHMMA_02243 4.3e-76 yvbF K Belongs to the GbsR family
IICHHMMA_02244 9.2e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IICHHMMA_02245 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IICHHMMA_02246 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IICHHMMA_02247 2.1e-126 mutF V ABC transporter, ATP-binding protein
IICHHMMA_02248 6e-121 spaE S ABC-2 family transporter protein
IICHHMMA_02249 3.1e-136 mutG S ABC-2 family transporter protein
IICHHMMA_02250 5.4e-121 K Transcriptional regulatory protein, C terminal
IICHHMMA_02251 9.1e-259 T His Kinase A (phosphoacceptor) domain
IICHHMMA_02252 8.8e-53 yodB K transcriptional
IICHHMMA_02253 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
IICHHMMA_02254 1.8e-69 K transcriptional
IICHHMMA_02255 6e-35 yvzC K Transcriptional
IICHHMMA_02256 4.8e-24 secG U Preprotein translocase subunit SecG
IICHHMMA_02257 1.6e-142 est 3.1.1.1 S Carboxylesterase
IICHHMMA_02258 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IICHHMMA_02259 3.5e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IICHHMMA_02262 6e-56
IICHHMMA_02263 2.4e-47 yrdF K ribonuclease inhibitor
IICHHMMA_02264 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IICHHMMA_02265 4.7e-160 ytlI K LysR substrate binding domain
IICHHMMA_02266 8.7e-101 ytmI K Acetyltransferase (GNAT) domain
IICHHMMA_02267 3.5e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
IICHHMMA_02268 5.4e-147 tcyK M Bacterial periplasmic substrate-binding proteins
IICHHMMA_02269 2.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
IICHHMMA_02270 2.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
IICHHMMA_02271 8e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IICHHMMA_02272 2.1e-180 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IICHHMMA_02273 3.6e-45 ytnI O COG0695 Glutaredoxin and related proteins
IICHHMMA_02274 9.2e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IICHHMMA_02275 2.5e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IICHHMMA_02276 1.6e-191 yvaA 1.1.1.371 S Oxidoreductase
IICHHMMA_02277 1.4e-47 csoR S transcriptional
IICHHMMA_02278 2.6e-29 copZ P Heavy-metal-associated domain
IICHHMMA_02279 0.0 copA 3.6.3.54 P P-type ATPase
IICHHMMA_02280 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IICHHMMA_02281 2.3e-98 bdbD O Thioredoxin
IICHHMMA_02282 1e-72 bdbC O Required for disulfide bond formation in some proteins
IICHHMMA_02283 9.7e-141 S Metallo-peptidase family M12
IICHHMMA_02284 7.8e-98 yvgT S membrane
IICHHMMA_02285 0.0 helD 3.6.4.12 L DNA helicase
IICHHMMA_02286 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IICHHMMA_02287 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IICHHMMA_02288 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
IICHHMMA_02289 2.7e-85 yvgO
IICHHMMA_02290 6.5e-156 yvgN S reductase
IICHHMMA_02291 5.6e-190 yfiN V COG0842 ABC-type multidrug transport system, permease component
IICHHMMA_02292 1.1e-192 yfiM V ABC-2 type transporter
IICHHMMA_02293 2.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
IICHHMMA_02294 9.6e-179 T Histidine kinase
IICHHMMA_02295 2.1e-112 yfiK K Regulator
IICHHMMA_02296 4.6e-99 modB P COG4149 ABC-type molybdate transport system, permease component
IICHHMMA_02297 2.4e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
IICHHMMA_02298 6.6e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
IICHHMMA_02299 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IICHHMMA_02300 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
IICHHMMA_02301 5.2e-13 S Small spore protein J (Spore_SspJ)
IICHHMMA_02302 9.2e-235 yvsH E Arginine ornithine antiporter
IICHHMMA_02303 1.2e-126 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IICHHMMA_02304 2.2e-176 fhuD P ABC transporter
IICHHMMA_02305 1.9e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IICHHMMA_02306 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IICHHMMA_02307 1.8e-147 fhuC 3.6.3.34 HP ABC transporter
IICHHMMA_02308 7.9e-65 yvrL S Regulatory protein YrvL
IICHHMMA_02309 3.5e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
IICHHMMA_02310 6.1e-15 S YvrJ protein family
IICHHMMA_02311 9.9e-103 yvrI K RNA polymerase
IICHHMMA_02312 1.1e-36
IICHHMMA_02313 7.4e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICHHMMA_02314 0.0 T PhoQ Sensor
IICHHMMA_02315 6.4e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
IICHHMMA_02316 2.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IICHHMMA_02317 3.5e-166 yvrC P ABC transporter substrate-binding protein
IICHHMMA_02318 3.9e-177 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IICHHMMA_02319 1.6e-219 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IICHHMMA_02320 5.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
IICHHMMA_02321 3.7e-227 yvqJ EGP Major facilitator Superfamily
IICHHMMA_02322 5.3e-44 liaI S membrane
IICHHMMA_02323 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IICHHMMA_02324 9.6e-126 liaG S Putative adhesin
IICHHMMA_02325 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
IICHHMMA_02326 2.3e-193 vraS 2.7.13.3 T Histidine kinase
IICHHMMA_02327 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IICHHMMA_02328 1.5e-203 gerAC S Spore germination B3/ GerAC like, C-terminal
IICHHMMA_02329 8.9e-185 gerAB E Spore germination protein
IICHHMMA_02330 1.4e-259 gerAA EG Spore germination protein
IICHHMMA_02331 6.6e-24 S Protein of unknown function (DUF3970)
IICHHMMA_02332 3.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IICHHMMA_02333 1e-157 yuxN K Transcriptional regulator
IICHHMMA_02334 3.4e-24
IICHHMMA_02335 6.3e-249 cssS 2.7.13.3 T PhoQ Sensor
IICHHMMA_02336 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICHHMMA_02337 3.8e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IICHHMMA_02338 1.6e-79 dps P Belongs to the Dps family
IICHHMMA_02339 8.7e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IICHHMMA_02340 0.0 pepF2 E COG1164 Oligoendopeptidase F
IICHHMMA_02341 4.2e-45 S YusW-like protein
IICHHMMA_02342 3.1e-150 yusV 3.6.3.34 HP ABC transporter
IICHHMMA_02343 3.3e-39 yusU S Protein of unknown function (DUF2573)
IICHHMMA_02344 6.9e-187 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IICHHMMA_02345 2.7e-137 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
IICHHMMA_02346 1e-154 ywbI2 K Transcriptional regulator
IICHHMMA_02347 8.1e-288 yusP P Major facilitator superfamily
IICHHMMA_02348 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
IICHHMMA_02349 1.1e-53 yusN M Coat F domain
IICHHMMA_02350 6.7e-43
IICHHMMA_02351 1.8e-210 yusP P Major facilitator superfamily
IICHHMMA_02352 4.9e-165 fadM E Proline dehydrogenase
IICHHMMA_02353 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
IICHHMMA_02354 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
IICHHMMA_02355 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
IICHHMMA_02356 1.4e-62 arsC 1.20.4.1 P Belongs to the ArsC family
IICHHMMA_02357 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IICHHMMA_02358 3.7e-40 yusG S Protein of unknown function (DUF2553)
IICHHMMA_02359 4.9e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
IICHHMMA_02360 1.6e-54 yusE CO Thioredoxin
IICHHMMA_02361 1.5e-56 yusD S SCP-2 sterol transfer family
IICHHMMA_02362 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IICHHMMA_02363 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
IICHHMMA_02364 3e-145 metQ P Belongs to the NlpA lipoprotein family
IICHHMMA_02365 4.9e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IICHHMMA_02366 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IICHHMMA_02367 1.2e-244 sufD O assembly protein SufD
IICHHMMA_02368 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IICHHMMA_02369 1.1e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
IICHHMMA_02370 8.7e-270 sufB O FeS cluster assembly
IICHHMMA_02371 5e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IICHHMMA_02372 6.1e-79 yncE S Protein of unknown function (DUF2691)
IICHHMMA_02373 2.9e-120 Q ubiE/COQ5 methyltransferase family
IICHHMMA_02374 1.8e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
IICHHMMA_02375 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
IICHHMMA_02377 1.6e-22 S Sporulation delaying protein SdpA
IICHHMMA_02378 3.4e-76
IICHHMMA_02379 1.2e-13
IICHHMMA_02380 2.9e-165 K helix_turn_helix, mercury resistance
IICHHMMA_02381 3e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IICHHMMA_02382 3.1e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
IICHHMMA_02383 1.5e-158 yurN G Binding-protein-dependent transport system inner membrane component
IICHHMMA_02384 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
IICHHMMA_02385 3.4e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
IICHHMMA_02386 1.2e-134 yurK K UTRA
IICHHMMA_02387 7.7e-205 msmX P Belongs to the ABC transporter superfamily
IICHHMMA_02388 5e-167 bsn L Ribonuclease
IICHHMMA_02389 8.9e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IICHHMMA_02390 8.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IICHHMMA_02391 6e-211 blt EGP Major facilitator Superfamily
IICHHMMA_02393 4.7e-15 yqbD 2.1.1.72 L Putative phage serine protease XkdF
IICHHMMA_02394 4.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
IICHHMMA_02395 1.6e-260 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IICHHMMA_02396 1.4e-59 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
IICHHMMA_02397 6.9e-169 yunF S Protein of unknown function DUF72
IICHHMMA_02398 5.1e-145 yunE S membrane transporter protein
IICHHMMA_02399 7.1e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IICHHMMA_02400 2.5e-130 yunB S Sporulation protein YunB (Spo_YunB)
IICHHMMA_02401 1.5e-191 lytH M Peptidase, M23
IICHHMMA_02402 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IICHHMMA_02403 1.7e-47 yutD S protein conserved in bacteria
IICHHMMA_02404 6.8e-72 yutE S Protein of unknown function DUF86
IICHHMMA_02405 2.3e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IICHHMMA_02406 1.9e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
IICHHMMA_02407 7.4e-194 yutH S Spore coat protein
IICHHMMA_02408 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
IICHHMMA_02409 6.3e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IICHHMMA_02410 8.3e-168 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IICHHMMA_02411 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
IICHHMMA_02412 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
IICHHMMA_02413 2.8e-54 yuzD S protein conserved in bacteria
IICHHMMA_02414 4.2e-208 yutJ 1.6.99.3 C NADH dehydrogenase
IICHHMMA_02415 2.4e-39 yuzB S Belongs to the UPF0349 family
IICHHMMA_02416 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IICHHMMA_02417 3.7e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IICHHMMA_02418 1.1e-62 erpA S Belongs to the HesB IscA family
IICHHMMA_02420 2.4e-136 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
IICHHMMA_02422 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
IICHHMMA_02424 1.5e-121 V ABC transporter
IICHHMMA_02425 4.8e-64 CP Membrane
IICHHMMA_02426 4.8e-29
IICHHMMA_02427 6.7e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IICHHMMA_02429 2.5e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
IICHHMMA_02430 1.5e-233 yumB 1.6.99.3 C NADH dehydrogenase
IICHHMMA_02431 9.9e-28 yuiB S Putative membrane protein
IICHHMMA_02432 2.7e-117 yuiC S protein conserved in bacteria
IICHHMMA_02433 1.6e-77 yuiD S protein conserved in bacteria
IICHHMMA_02434 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IICHHMMA_02435 9e-208 yuiF S antiporter
IICHHMMA_02436 1.5e-101 bioY S Biotin biosynthesis protein
IICHHMMA_02437 9.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
IICHHMMA_02438 1.5e-163 besA S Putative esterase
IICHHMMA_02439 4.8e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IICHHMMA_02440 2.9e-221 entC 5.4.4.2 HQ Isochorismate synthase
IICHHMMA_02441 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
IICHHMMA_02442 2.5e-172 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
IICHHMMA_02443 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_02444 1.1e-33 mbtH S MbtH-like protein
IICHHMMA_02445 4.8e-133 yukJ S Uncharacterized conserved protein (DUF2278)
IICHHMMA_02446 1.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
IICHHMMA_02447 4.2e-228 yukF QT Transcriptional regulator
IICHHMMA_02448 3.3e-46 esxA S Belongs to the WXG100 family
IICHHMMA_02449 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
IICHHMMA_02450 4e-205 essB S WXG100 protein secretion system (Wss), protein YukC
IICHHMMA_02451 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IICHHMMA_02452 0.0 esaA S type VII secretion protein EsaA
IICHHMMA_02453 2.1e-74 yueC S Family of unknown function (DUF5383)
IICHHMMA_02454 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IICHHMMA_02455 8.3e-96 yueE S phosphohydrolase
IICHHMMA_02456 1.6e-22 S Protein of unknown function (DUF2642)
IICHHMMA_02457 3.6e-186 yueF S transporter activity
IICHHMMA_02458 6.4e-34 yueG S Spore germination protein gerPA/gerPF
IICHHMMA_02459 2.8e-38 yueH S YueH-like protein
IICHHMMA_02460 7.2e-68 yueI S Protein of unknown function (DUF1694)
IICHHMMA_02461 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
IICHHMMA_02462 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IICHHMMA_02463 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
IICHHMMA_02464 1.2e-50 yuzC
IICHHMMA_02466 7.6e-62 comQ H Belongs to the FPP GGPP synthase family
IICHHMMA_02468 1.1e-256 comP 2.7.13.3 T Histidine kinase
IICHHMMA_02469 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IICHHMMA_02470 3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
IICHHMMA_02471 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
IICHHMMA_02472 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IICHHMMA_02473 7.7e-77 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IICHHMMA_02474 4.9e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IICHHMMA_02475 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IICHHMMA_02476 2.7e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IICHHMMA_02477 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IICHHMMA_02478 8.9e-12
IICHHMMA_02479 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
IICHHMMA_02480 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
IICHHMMA_02481 2.8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IICHHMMA_02482 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IICHHMMA_02483 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
IICHHMMA_02484 6.4e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IICHHMMA_02485 9.3e-74 yufK S Family of unknown function (DUF5366)
IICHHMMA_02486 1.7e-72 yuxK S protein conserved in bacteria
IICHHMMA_02487 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
IICHHMMA_02488 1.8e-178 yuxJ EGP Major facilitator Superfamily
IICHHMMA_02489 4e-118 kapD L the KinA pathway to sporulation
IICHHMMA_02490 7.7e-67 kapB G Kinase associated protein B
IICHHMMA_02491 4.4e-228 T PhoQ Sensor
IICHHMMA_02492 4.6e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IICHHMMA_02493 1.4e-40 yugE S Domain of unknown function (DUF1871)
IICHHMMA_02494 5.5e-155 yugF I Hydrolase
IICHHMMA_02495 2e-83 alaR K Transcriptional regulator
IICHHMMA_02496 7.2e-209 yugH 2.6.1.1 E Aminotransferase
IICHHMMA_02497 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
IICHHMMA_02498 1.8e-34 yuzA S Domain of unknown function (DUF378)
IICHHMMA_02499 1.7e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
IICHHMMA_02500 6.2e-229 yugK C Dehydrogenase
IICHHMMA_02501 2.1e-117 ycaC Q Isochorismatase family
IICHHMMA_02502 1.7e-94 S NADPH-dependent FMN reductase
IICHHMMA_02503 1.1e-258 pgi 5.3.1.9 G Belongs to the GPI family
IICHHMMA_02505 1.2e-70 yugN S YugN-like family
IICHHMMA_02506 1.1e-181 yugO P COG1226 Kef-type K transport systems
IICHHMMA_02507 6.7e-27 mstX S Membrane-integrating protein Mistic
IICHHMMA_02508 3.4e-18
IICHHMMA_02509 8.3e-117 yugP S Zn-dependent protease
IICHHMMA_02510 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
IICHHMMA_02511 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
IICHHMMA_02512 3.5e-73 yugU S Uncharacterised protein family UPF0047
IICHHMMA_02513 8.6e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IICHHMMA_02514 9e-40
IICHHMMA_02515 4.2e-60 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
IICHHMMA_02516 7.2e-110 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
IICHHMMA_02517 8.1e-221 mcpA NT chemotaxis protein
IICHHMMA_02518 3.4e-235 mcpA NT chemotaxis protein
IICHHMMA_02519 3e-223 mcpA NT chemotaxis protein
IICHHMMA_02520 1.9e-233 mcpA NT chemotaxis protein
IICHHMMA_02521 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
IICHHMMA_02522 7.9e-185 ygjR S Oxidoreductase
IICHHMMA_02523 1.7e-194 yubA S transporter activity
IICHHMMA_02524 4e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IICHHMMA_02526 1.5e-13
IICHHMMA_02527 7.6e-131 S Aspartate phosphatase response regulator
IICHHMMA_02531 5.8e-52 yjcN
IICHHMMA_02532 4.6e-117 G Cupin
IICHHMMA_02533 6.5e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IICHHMMA_02534 1.1e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IICHHMMA_02535 5.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
IICHHMMA_02536 1e-93 yuaB
IICHHMMA_02537 2.5e-95 yuaC K Belongs to the GbsR family
IICHHMMA_02538 1.6e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
IICHHMMA_02539 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
IICHHMMA_02540 1.9e-80 yuaD S MOSC domain
IICHHMMA_02541 5.3e-73 yuaE S DinB superfamily
IICHHMMA_02542 1.6e-83 yuaF OU Membrane protein implicated in regulation of membrane protease activity
IICHHMMA_02543 1.7e-178 yuaG 3.4.21.72 S protein conserved in bacteria
IICHHMMA_02544 5.3e-96 thiT S Thiamine transporter protein (Thia_YuaJ)
IICHHMMA_02545 3.9e-218 glcP G Major Facilitator Superfamily
IICHHMMA_02546 2.1e-246 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IICHHMMA_02547 1.2e-177 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
IICHHMMA_02548 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
IICHHMMA_02549 3.5e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
IICHHMMA_02550 6.3e-174 ybaS 1.1.1.58 S Na -dependent transporter
IICHHMMA_02551 1.3e-107 ybbA S Putative esterase
IICHHMMA_02552 4.7e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IICHHMMA_02553 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IICHHMMA_02554 4.4e-172 feuA P Iron-uptake system-binding protein
IICHHMMA_02555 2e-307 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
IICHHMMA_02556 4.3e-236 ybbC 3.2.1.52 S protein conserved in bacteria
IICHHMMA_02557 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
IICHHMMA_02558 1.3e-243 yfeW 3.4.16.4 V Belongs to the UPF0214 family
IICHHMMA_02559 1.6e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IICHHMMA_02560 5.8e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IICHHMMA_02561 7.7e-85 ybbJ J acetyltransferase
IICHHMMA_02562 8.7e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
IICHHMMA_02568 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
IICHHMMA_02569 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IICHHMMA_02570 8.7e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IICHHMMA_02571 1.8e-222 ybbR S protein conserved in bacteria
IICHHMMA_02572 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IICHHMMA_02573 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IICHHMMA_02574 5.2e-156 V ATPases associated with a variety of cellular activities
IICHHMMA_02575 2.2e-106 S ABC-2 family transporter protein
IICHHMMA_02576 2e-97 ybdN
IICHHMMA_02577 7.8e-131 ybdO S Domain of unknown function (DUF4885)
IICHHMMA_02578 9.6e-163 dkgB S Aldo/keto reductase family
IICHHMMA_02579 4.7e-91 yxaC M effector of murein hydrolase
IICHHMMA_02580 2e-51 S LrgA family
IICHHMMA_02581 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
IICHHMMA_02582 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
IICHHMMA_02583 1.5e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IICHHMMA_02584 6.2e-104 T Histidine kinase
IICHHMMA_02585 4.2e-81 KT helix_turn_helix, Lux Regulon
IICHHMMA_02586 2.7e-134 V ABC transporter, ATP-binding protein
IICHHMMA_02587 2e-145 V ABC-2 type transporter
IICHHMMA_02588 3.5e-123 V ABC-2 type transporter
IICHHMMA_02589 4.4e-14
IICHHMMA_02590 6.9e-58 bacT Q Thioesterase domain
IICHHMMA_02591 7.5e-77 ctsR K Belongs to the CtsR family
IICHHMMA_02592 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
IICHHMMA_02593 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IICHHMMA_02594 0.0 clpC O Belongs to the ClpA ClpB family
IICHHMMA_02595 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IICHHMMA_02596 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IICHHMMA_02597 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
IICHHMMA_02598 7.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IICHHMMA_02599 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IICHHMMA_02600 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IICHHMMA_02601 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
IICHHMMA_02602 9e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IICHHMMA_02603 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IICHHMMA_02604 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IICHHMMA_02605 4.2e-89 yacP S RNA-binding protein containing a PIN domain
IICHHMMA_02606 8.9e-116 sigH K Belongs to the sigma-70 factor family
IICHHMMA_02607 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IICHHMMA_02608 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
IICHHMMA_02609 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IICHHMMA_02610 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IICHHMMA_02611 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IICHHMMA_02612 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IICHHMMA_02613 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
IICHHMMA_02614 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IICHHMMA_02615 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IICHHMMA_02616 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
IICHHMMA_02617 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IICHHMMA_02618 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IICHHMMA_02619 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IICHHMMA_02620 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IICHHMMA_02621 1.7e-184 ybaC 3.4.11.5 S Alpha/beta hydrolase family
IICHHMMA_02622 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IICHHMMA_02623 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IICHHMMA_02624 3e-105 rplD J Forms part of the polypeptide exit tunnel
IICHHMMA_02625 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IICHHMMA_02626 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IICHHMMA_02627 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IICHHMMA_02628 5.6e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IICHHMMA_02629 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IICHHMMA_02630 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IICHHMMA_02631 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IICHHMMA_02632 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IICHHMMA_02633 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IICHHMMA_02634 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IICHHMMA_02635 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IICHHMMA_02636 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IICHHMMA_02637 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IICHHMMA_02638 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IICHHMMA_02639 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IICHHMMA_02640 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IICHHMMA_02641 1.9e-23 rpmD J Ribosomal protein L30
IICHHMMA_02642 4.1e-72 rplO J binds to the 23S rRNA
IICHHMMA_02643 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IICHHMMA_02644 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IICHHMMA_02645 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
IICHHMMA_02646 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IICHHMMA_02647 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IICHHMMA_02648 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IICHHMMA_02649 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IICHHMMA_02650 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IICHHMMA_02651 4.7e-58 rplQ J Ribosomal protein L17
IICHHMMA_02652 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IICHHMMA_02653 2.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IICHHMMA_02654 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IICHHMMA_02655 9.1e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IICHHMMA_02656 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IICHHMMA_02657 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
IICHHMMA_02658 9e-144 ybaJ Q Methyltransferase domain
IICHHMMA_02659 1.4e-83 yizA S Damage-inducible protein DinB
IICHHMMA_02660 6.5e-78 ybaK S Protein of unknown function (DUF2521)
IICHHMMA_02661 4.6e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IICHHMMA_02662 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IICHHMMA_02663 1.7e-75 gerD
IICHHMMA_02664 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
IICHHMMA_02665 1.3e-131 pdaB 3.5.1.104 G Polysaccharide deacetylase
IICHHMMA_02666 2.3e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
IICHHMMA_02667 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IICHHMMA_02668 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IICHHMMA_02669 1.4e-66 ypoP K transcriptional
IICHHMMA_02670 6.1e-97 ypmS S protein conserved in bacteria
IICHHMMA_02671 3.4e-135 ypmR E GDSL-like Lipase/Acylhydrolase
IICHHMMA_02672 1.9e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IICHHMMA_02673 2.9e-38 ypmP S Protein of unknown function (DUF2535)
IICHHMMA_02674 1.4e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IICHHMMA_02675 1.1e-173 pspF K Transcriptional regulator
IICHHMMA_02676 4.6e-109 hlyIII S protein, Hemolysin III
IICHHMMA_02677 1.3e-113 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IICHHMMA_02678 1.5e-88 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IICHHMMA_02679 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IICHHMMA_02680 1e-113 ypjP S YpjP-like protein
IICHHMMA_02681 2.6e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
IICHHMMA_02682 1e-75 yphP S Belongs to the UPF0403 family
IICHHMMA_02683 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IICHHMMA_02684 4.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
IICHHMMA_02685 3.5e-98 ypgQ S phosphohydrolase
IICHHMMA_02686 1.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IICHHMMA_02687 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IICHHMMA_02688 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IICHHMMA_02689 1e-30 cspD K Cold-shock protein
IICHHMMA_02690 1.1e-10 degR
IICHHMMA_02691 1.2e-36 S Protein of unknown function (DUF2564)
IICHHMMA_02692 1.5e-28 ypeQ S Zinc-finger
IICHHMMA_02693 1.4e-121 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
IICHHMMA_02694 2.2e-117 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IICHHMMA_02695 1.6e-67 rnhA 3.1.26.4 L Ribonuclease
IICHHMMA_02697 6.5e-162 polA 2.7.7.7 L 5'3' exonuclease
IICHHMMA_02699 1e-38 ypbS S Protein of unknown function (DUF2533)
IICHHMMA_02700 0.0 ypbR S Dynamin family
IICHHMMA_02701 2.1e-88 ypbQ S protein conserved in bacteria
IICHHMMA_02702 2.7e-202 bcsA Q Naringenin-chalcone synthase
IICHHMMA_02703 1.8e-75 J Acetyltransferase (GNAT) domain
IICHHMMA_02704 1.5e-49 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
IICHHMMA_02706 1.1e-21 ydfR S Protein of unknown function (DUF421)
IICHHMMA_02707 6.6e-55 ydfR S Protein of unknown function (DUF421)
IICHHMMA_02708 3.2e-98 yrdC 3.5.1.19 Q Isochorismatase family
IICHHMMA_02710 2.2e-235 pbuX F xanthine
IICHHMMA_02711 3.7e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IICHHMMA_02712 5.1e-284 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IICHHMMA_02713 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
IICHHMMA_02715 6.6e-22 S YpzG-like protein
IICHHMMA_02716 5.9e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IICHHMMA_02717 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IICHHMMA_02718 3.1e-98 ypsA S Belongs to the UPF0398 family
IICHHMMA_02719 9.9e-33 cotD S Inner spore coat protein D
IICHHMMA_02721 8e-235 yprB L RNase_H superfamily
IICHHMMA_02722 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IICHHMMA_02723 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
IICHHMMA_02724 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
IICHHMMA_02725 1.4e-42 yppG S YppG-like protein
IICHHMMA_02727 2.6e-11 yppE S Bacterial domain of unknown function (DUF1798)
IICHHMMA_02730 1.4e-186 yppC S Protein of unknown function (DUF2515)
IICHHMMA_02731 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IICHHMMA_02732 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IICHHMMA_02733 5.7e-91 ypoC
IICHHMMA_02734 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IICHHMMA_02735 3e-130 dnaD L DNA replication protein DnaD
IICHHMMA_02736 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
IICHHMMA_02737 9.7e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IICHHMMA_02738 1.5e-80 ypmB S protein conserved in bacteria
IICHHMMA_02739 6.7e-23 ypmA S Protein of unknown function (DUF4264)
IICHHMMA_02740 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IICHHMMA_02741 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IICHHMMA_02742 5.5e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IICHHMMA_02743 3.8e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IICHHMMA_02744 6.2e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IICHHMMA_02745 3.1e-215 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IICHHMMA_02746 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
IICHHMMA_02747 1.9e-132 bshB1 S proteins, LmbE homologs
IICHHMMA_02748 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
IICHHMMA_02749 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IICHHMMA_02750 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
IICHHMMA_02751 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
IICHHMMA_02752 5e-226 oxdC 4.1.1.2 G Oxalate decarboxylase
IICHHMMA_02753 1.9e-141 ypjB S sporulation protein
IICHHMMA_02754 1.4e-104 ypjA S membrane
IICHHMMA_02755 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
IICHHMMA_02756 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
IICHHMMA_02757 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
IICHHMMA_02758 3.2e-77 ypiF S Protein of unknown function (DUF2487)
IICHHMMA_02759 2.1e-99 ypiB S Belongs to the UPF0302 family
IICHHMMA_02760 4.5e-233 S COG0457 FOG TPR repeat
IICHHMMA_02761 2e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IICHHMMA_02762 8.6e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IICHHMMA_02763 4.2e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IICHHMMA_02764 4.2e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IICHHMMA_02765 7.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IICHHMMA_02766 1.8e-113 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IICHHMMA_02767 4.7e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IICHHMMA_02768 2.3e-155 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IICHHMMA_02769 1.1e-289 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IICHHMMA_02770 1.5e-59 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IICHHMMA_02771 1.6e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IICHHMMA_02772 2.1e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IICHHMMA_02773 3e-139 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
IICHHMMA_02774 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IICHHMMA_02775 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IICHHMMA_02776 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IICHHMMA_02777 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IICHHMMA_02778 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IICHHMMA_02779 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
IICHHMMA_02780 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IICHHMMA_02781 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IICHHMMA_02782 1.2e-132 yphF
IICHHMMA_02783 3.3e-16 yphE S Protein of unknown function (DUF2768)
IICHHMMA_02784 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IICHHMMA_02785 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IICHHMMA_02786 9.4e-104 yphA
IICHHMMA_02787 4.7e-08 S YpzI-like protein
IICHHMMA_02788 1.7e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IICHHMMA_02789 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
IICHHMMA_02790 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IICHHMMA_02791 1.4e-12 S Family of unknown function (DUF5359)
IICHHMMA_02792 3.1e-60 ypfA M Flagellar protein YcgR
IICHHMMA_02793 1.3e-249 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
IICHHMMA_02794 3.9e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
IICHHMMA_02795 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
IICHHMMA_02796 7.7e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
IICHHMMA_02797 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IICHHMMA_02798 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IICHHMMA_02799 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
IICHHMMA_02800 2.8e-84 ypbF S Protein of unknown function (DUF2663)
IICHHMMA_02801 1.2e-74 ypbE M Lysin motif
IICHHMMA_02802 9.8e-98 ypbD S metal-dependent membrane protease
IICHHMMA_02803 5.2e-270 recQ 3.6.4.12 L DNA helicase
IICHHMMA_02804 2.4e-195 ypbB 5.1.3.1 S protein conserved in bacteria
IICHHMMA_02805 3.6e-41 fer C Ferredoxin
IICHHMMA_02806 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IICHHMMA_02807 2.8e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IICHHMMA_02808 5.2e-193 rsiX
IICHHMMA_02809 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
IICHHMMA_02810 0.0 resE 2.7.13.3 T Histidine kinase
IICHHMMA_02811 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICHHMMA_02812 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IICHHMMA_02813 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
IICHHMMA_02814 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IICHHMMA_02815 1.3e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IICHHMMA_02816 1.3e-88 spmB S Spore maturation protein
IICHHMMA_02817 2e-103 spmA S Spore maturation protein
IICHHMMA_02818 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
IICHHMMA_02819 3.8e-93 ypuI S Protein of unknown function (DUF3907)
IICHHMMA_02820 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IICHHMMA_02821 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IICHHMMA_02823 1.2e-91 ypuF S Domain of unknown function (DUF309)
IICHHMMA_02824 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IICHHMMA_02825 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IICHHMMA_02826 1.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IICHHMMA_02827 5.5e-110 ribE 2.5.1.9 H Riboflavin synthase
IICHHMMA_02828 4e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IICHHMMA_02829 6.4e-49 ypuD
IICHHMMA_02830 1.7e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IICHHMMA_02831 2.2e-82 ccdC1 O Protein of unknown function (DUF1453)
IICHHMMA_02832 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IICHHMMA_02833 1.9e-153 ypuA S Secreted protein
IICHHMMA_02834 1.2e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IICHHMMA_02835 3.2e-270 spoVAF EG Stage V sporulation protein AF
IICHHMMA_02836 2e-109 spoVAEA S stage V sporulation protein
IICHHMMA_02837 5e-57 spoVAEB S stage V sporulation protein
IICHHMMA_02838 4.2e-189 spoVAD I Stage V sporulation protein AD
IICHHMMA_02839 6e-79 spoVAC S stage V sporulation protein AC
IICHHMMA_02840 1.5e-59 spoVAB S Stage V sporulation protein AB
IICHHMMA_02841 8.1e-111 spoVAA S Stage V sporulation protein AA
IICHHMMA_02842 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IICHHMMA_02843 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IICHHMMA_02844 1.7e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
IICHHMMA_02845 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
IICHHMMA_02846 2.4e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IICHHMMA_02847 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IICHHMMA_02848 1.7e-165 xerD L recombinase XerD
IICHHMMA_02849 3.7e-37 S Protein of unknown function (DUF4227)
IICHHMMA_02850 1.9e-80 fur P Belongs to the Fur family
IICHHMMA_02851 9.4e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IICHHMMA_02853 6.6e-34 yqkK
IICHHMMA_02854 5.7e-22
IICHHMMA_02855 2.5e-242 mleA 1.1.1.38 C malic enzyme
IICHHMMA_02856 2.9e-241 mleN C Na H antiporter
IICHHMMA_02857 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
IICHHMMA_02858 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
IICHHMMA_02859 1e-57 ansR K Transcriptional regulator
IICHHMMA_02860 2.4e-220 yqxK 3.6.4.12 L DNA helicase
IICHHMMA_02861 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
IICHHMMA_02863 8.2e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
IICHHMMA_02865 2.8e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
IICHHMMA_02866 3.2e-39 yqkC S Protein of unknown function (DUF2552)
IICHHMMA_02867 7.7e-61 yqkB S Belongs to the HesB IscA family
IICHHMMA_02868 5.8e-172 yqkA K GrpB protein
IICHHMMA_02869 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
IICHHMMA_02870 8.7e-89 yqjY K acetyltransferase
IICHHMMA_02871 5.2e-234 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IICHHMMA_02872 4.9e-57 S YolD-like protein
IICHHMMA_02874 1.6e-71 yueF S transporter activity
IICHHMMA_02876 2.5e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IICHHMMA_02877 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IICHHMMA_02878 2.3e-251 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IICHHMMA_02879 1.9e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
IICHHMMA_02880 1.2e-174 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
IICHHMMA_02881 2.4e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IICHHMMA_02882 4.4e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IICHHMMA_02883 7.4e-239 pksG 2.3.3.10 I synthase
IICHHMMA_02884 5.2e-220 eryK 1.14.13.154 C Cytochrome P450
IICHHMMA_02885 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IICHHMMA_02886 0.0 Q Polyketide synthase of type I
IICHHMMA_02887 0.0 pfaA Q Polyketide synthase of type I
IICHHMMA_02888 0.0 pksJ Q Polyketide synthase of type I
IICHHMMA_02892 1.6e-08
IICHHMMA_02899 1.3e-09
IICHHMMA_02900 7.8e-08
IICHHMMA_02909 2.6e-77 tspO T membrane
IICHHMMA_02910 2.4e-130 dksA T COG1734 DnaK suppressor protein
IICHHMMA_02911 2.1e-271 menF 5.4.4.2 HQ Isochorismate synthase
IICHHMMA_02912 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IICHHMMA_02913 3.2e-155 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IICHHMMA_02914 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IICHHMMA_02915 3.2e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IICHHMMA_02916 4.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IICHHMMA_02917 2e-23 S Domain of Unknown Function (DUF1540)
IICHHMMA_02918 5.4e-184 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IICHHMMA_02919 6.4e-238 cydA 1.10.3.14 C oxidase, subunit
IICHHMMA_02920 7.9e-41 rpmE2 J Ribosomal protein L31
IICHHMMA_02921 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IICHHMMA_02922 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IICHHMMA_02923 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IICHHMMA_02924 6.1e-76 ytkA S YtkA-like
IICHHMMA_02926 7.8e-76 dps P Belongs to the Dps family
IICHHMMA_02927 1.5e-60 ytkC S Bacteriophage holin family
IICHHMMA_02928 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
IICHHMMA_02929 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IICHHMMA_02930 3.2e-144 ytlC P ABC transporter
IICHHMMA_02931 8.9e-184 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IICHHMMA_02932 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IICHHMMA_02933 1.6e-38 ytmB S Protein of unknown function (DUF2584)
IICHHMMA_02934 7.7e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IICHHMMA_02935 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IICHHMMA_02936 0.0 asnB 6.3.5.4 E Asparagine synthase
IICHHMMA_02937 6.3e-260 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
IICHHMMA_02938 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IICHHMMA_02939 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
IICHHMMA_02940 7.1e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
IICHHMMA_02942 2.5e-106 ytqB J Putative rRNA methylase
IICHHMMA_02943 2.1e-190 yhcC S Fe-S oxidoreductase
IICHHMMA_02944 1.3e-39 ytzC S Protein of unknown function (DUF2524)
IICHHMMA_02946 3.9e-66 ytrA K GntR family transcriptional regulator
IICHHMMA_02947 1.9e-161 ytrB P abc transporter atp-binding protein
IICHHMMA_02948 2.2e-166 S ABC-2 family transporter protein
IICHHMMA_02949 5.4e-157 P ABC-2 family transporter protein
IICHHMMA_02950 9.8e-151
IICHHMMA_02951 1.5e-124 ytrE V ABC transporter, ATP-binding protein
IICHHMMA_02952 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
IICHHMMA_02953 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICHHMMA_02954 1.4e-162 T PhoQ Sensor
IICHHMMA_02955 4.9e-134 bceA V ABC transporter, ATP-binding protein
IICHHMMA_02956 0.0 bceB V ABC transporter (permease)
IICHHMMA_02957 2.9e-120 ywaF S Integral membrane protein
IICHHMMA_02958 4e-207 yttB EGP Major facilitator Superfamily
IICHHMMA_02959 9.9e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IICHHMMA_02960 1.2e-52 ytvB S Protein of unknown function (DUF4257)
IICHHMMA_02961 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IICHHMMA_02962 5.6e-52 ytwF P Sulfurtransferase
IICHHMMA_02963 1.5e-83 M Acetyltransferase (GNAT) domain
IICHHMMA_02964 4.8e-246 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IICHHMMA_02965 1.8e-142 amyC P ABC transporter (permease)
IICHHMMA_02966 8.2e-168 amyD G Binding-protein-dependent transport system inner membrane component
IICHHMMA_02967 7.5e-244 msmE G Bacterial extracellular solute-binding protein
IICHHMMA_02968 2.8e-185 msmR K Transcriptional regulator
IICHHMMA_02969 9e-26 yteV S Sporulation protein Cse60
IICHHMMA_02970 4.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
IICHHMMA_02971 5.7e-236 ytfP S HI0933-like protein
IICHHMMA_02972 3.8e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IICHHMMA_02973 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IICHHMMA_02974 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
IICHHMMA_02975 1.7e-128 ythP V ABC transporter
IICHHMMA_02976 9.6e-214 ythQ U Bacterial ABC transporter protein EcsB
IICHHMMA_02977 1.3e-227 pbuO S permease
IICHHMMA_02978 2.4e-267 pepV 3.5.1.18 E Dipeptidase
IICHHMMA_02979 3.1e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IICHHMMA_02980 2.8e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IICHHMMA_02981 1.1e-167 ytlQ
IICHHMMA_02982 1.2e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IICHHMMA_02983 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
IICHHMMA_02984 3.5e-45 ytzH S YtzH-like protein
IICHHMMA_02985 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IICHHMMA_02986 2.5e-163 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
IICHHMMA_02987 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
IICHHMMA_02988 1.7e-51 ytzB S small secreted protein
IICHHMMA_02989 2.9e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IICHHMMA_02990 1.6e-76 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
IICHHMMA_02991 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IICHHMMA_02992 1.9e-147 ytpQ S Belongs to the UPF0354 family
IICHHMMA_02993 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IICHHMMA_02994 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IICHHMMA_02995 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IICHHMMA_02996 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IICHHMMA_02997 1.7e-16 ytxH S COG4980 Gas vesicle protein
IICHHMMA_02998 8.5e-43 ytxJ O Protein of unknown function (DUF2847)
IICHHMMA_02999 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IICHHMMA_03000 6.4e-182 ccpA K catabolite control protein A
IICHHMMA_03001 1.9e-144 motA N flagellar motor
IICHHMMA_03002 3.1e-119 motS N Flagellar motor protein
IICHHMMA_03003 5.3e-228 acuC BQ histone deacetylase
IICHHMMA_03004 3.9e-116 acuB S Domain in cystathionine beta-synthase and other proteins.
IICHHMMA_03005 9.8e-120 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IICHHMMA_03006 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IICHHMMA_03007 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IICHHMMA_03008 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
IICHHMMA_03009 5.2e-125 azlC E AzlC protein
IICHHMMA_03010 1.3e-148 K Transcriptional regulator
IICHHMMA_03011 9.6e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IICHHMMA_03012 4.7e-137 E GDSL-like Lipase/Acylhydrolase family
IICHHMMA_03014 7.7e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
IICHHMMA_03015 3.3e-09
IICHHMMA_03016 2.8e-216 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IICHHMMA_03018 5.6e-47 S HicB_like antitoxin of bacterial toxin-antitoxin system
IICHHMMA_03020 4.7e-28
IICHHMMA_03022 2.9e-99 yokH G SMI1 / KNR4 family
IICHHMMA_03023 8.6e-254 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IICHHMMA_03024 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IICHHMMA_03025 9.5e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
IICHHMMA_03026 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
IICHHMMA_03027 5e-108 yttP K Transcriptional regulator
IICHHMMA_03028 1.7e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IICHHMMA_03029 8.9e-261 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IICHHMMA_03030 2.6e-239 braB E Component of the transport system for branched-chain amino acids
IICHHMMA_03031 2.7e-208 iscS2 2.8.1.7 E Cysteine desulfurase
IICHHMMA_03032 5.6e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IICHHMMA_03033 1.2e-29 sspB S spore protein
IICHHMMA_03034 1.1e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IICHHMMA_03035 6.6e-311 ytcJ S amidohydrolase
IICHHMMA_03036 2.8e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IICHHMMA_03037 6.4e-182 sppA OU signal peptide peptidase SppA
IICHHMMA_03038 1e-87 yteJ S RDD family
IICHHMMA_03039 1.7e-93 ytfI S Protein of unknown function (DUF2953)
IICHHMMA_03040 1.6e-60 ytfJ S Sporulation protein YtfJ
IICHHMMA_03041 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IICHHMMA_03042 9.1e-181 ytxK 2.1.1.72 L DNA methylase
IICHHMMA_03043 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IICHHMMA_03044 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IICHHMMA_03045 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IICHHMMA_03046 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
IICHHMMA_03048 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IICHHMMA_03049 1.3e-128 ytkL S Belongs to the UPF0173 family
IICHHMMA_03050 1.6e-236 ytoI K transcriptional regulator containing CBS domains
IICHHMMA_03051 1.5e-46 ytpI S YtpI-like protein
IICHHMMA_03052 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
IICHHMMA_03053 5.8e-23
IICHHMMA_03054 3.3e-86 ytrI
IICHHMMA_03055 9.2e-56 ytrH S Sporulation protein YtrH
IICHHMMA_03056 0.0 dnaE 2.7.7.7 L DNA polymerase
IICHHMMA_03057 7.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
IICHHMMA_03058 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IICHHMMA_03059 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IICHHMMA_03060 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IICHHMMA_03061 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IICHHMMA_03062 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
IICHHMMA_03063 2.4e-193 ytvI S sporulation integral membrane protein YtvI
IICHHMMA_03064 1.1e-72 yeaL S membrane
IICHHMMA_03065 4.2e-47 yjdF S Protein of unknown function (DUF2992)
IICHHMMA_03066 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
IICHHMMA_03067 1.2e-241 icd 1.1.1.42 C isocitrate
IICHHMMA_03068 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
IICHHMMA_03069 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICHHMMA_03070 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
IICHHMMA_03071 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IICHHMMA_03072 3.8e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IICHHMMA_03073 2.1e-106 ytaF P Probably functions as a manganese efflux pump
IICHHMMA_03074 9.2e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IICHHMMA_03075 7.6e-160 ytbE S reductase
IICHHMMA_03076 2.9e-205 ytbD EGP Major facilitator Superfamily
IICHHMMA_03077 2e-67 ytcD K Transcriptional regulator
IICHHMMA_03078 5.1e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IICHHMMA_03079 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IICHHMMA_03080 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IICHHMMA_03081 2e-253 dnaB L Membrane attachment protein
IICHHMMA_03082 9.5e-172 dnaI L Primosomal protein DnaI
IICHHMMA_03083 3.7e-106 ytxB S SNARE associated Golgi protein
IICHHMMA_03084 1.3e-151 ytxC S YtxC-like family
IICHHMMA_03085 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IICHHMMA_03086 7.9e-151 ysaA S HAD-hyrolase-like
IICHHMMA_03087 0.0 lytS 2.7.13.3 T Histidine kinase
IICHHMMA_03088 3.2e-130 lytT T COG3279 Response regulator of the LytR AlgR family
IICHHMMA_03089 2.9e-38 lrgA S effector of murein hydrolase LrgA
IICHHMMA_03090 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IICHHMMA_03091 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IICHHMMA_03092 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IICHHMMA_03093 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IICHHMMA_03094 7.7e-42 ysdA S Membrane
IICHHMMA_03095 1.7e-66 ysdB S Sigma-w pathway protein YsdB
IICHHMMA_03096 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
IICHHMMA_03097 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IICHHMMA_03098 9.9e-296 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IICHHMMA_03099 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
IICHHMMA_03100 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IICHHMMA_03101 9.2e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IICHHMMA_03102 1.8e-223 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IICHHMMA_03103 8.4e-251 araN G carbohydrate transport
IICHHMMA_03104 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
IICHHMMA_03105 1.2e-144 araQ G transport system permease
IICHHMMA_03106 2.1e-298 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
IICHHMMA_03107 0.0 cstA T Carbon starvation protein
IICHHMMA_03108 2.9e-254 glcF C Glycolate oxidase
IICHHMMA_03109 3.5e-258 glcD 1.1.3.15 C FAD binding domain
IICHHMMA_03110 2.3e-201 ysfB KT regulator
IICHHMMA_03111 2e-32 sspI S Belongs to the SspI family
IICHHMMA_03112 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IICHHMMA_03113 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IICHHMMA_03114 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IICHHMMA_03115 3.8e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IICHHMMA_03116 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IICHHMMA_03117 3.6e-83 cvpA S membrane protein, required for colicin V production
IICHHMMA_03118 0.0 polX L COG1796 DNA polymerase IV (family X)
IICHHMMA_03119 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IICHHMMA_03120 4.7e-67 yshE S membrane
IICHHMMA_03121 1.4e-119 ywbB S Protein of unknown function (DUF2711)
IICHHMMA_03122 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IICHHMMA_03123 2.7e-103 fadR K Transcriptional regulator
IICHHMMA_03124 2.7e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IICHHMMA_03125 5.7e-138 etfB C Electron transfer flavoprotein
IICHHMMA_03126 1.2e-177 etfA C Electron transfer flavoprotein
IICHHMMA_03127 1.5e-296 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
IICHHMMA_03128 2.5e-52 trxA O Belongs to the thioredoxin family
IICHHMMA_03129 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IICHHMMA_03130 4.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IICHHMMA_03131 5.9e-79 yslB S Protein of unknown function (DUF2507)
IICHHMMA_03132 4.8e-108 sdhC C succinate dehydrogenase
IICHHMMA_03133 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IICHHMMA_03134 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IICHHMMA_03135 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
IICHHMMA_03136 2e-30 gerE K Transcriptional regulator
IICHHMMA_03137 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
IICHHMMA_03138 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IICHHMMA_03139 5.3e-198 gerM S COG5401 Spore germination protein
IICHHMMA_03140 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IICHHMMA_03141 4.2e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IICHHMMA_03142 7.7e-91 ysnB S Phosphoesterase
IICHHMMA_03147 0.0 ilvB 2.2.1.6 E Acetolactate synthase
IICHHMMA_03148 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
IICHHMMA_03149 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IICHHMMA_03150 3e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IICHHMMA_03151 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IICHHMMA_03152 6.3e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IICHHMMA_03153 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IICHHMMA_03154 7.1e-189 ysoA H Tetratricopeptide repeat
IICHHMMA_03155 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IICHHMMA_03156 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IICHHMMA_03157 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
IICHHMMA_03158 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IICHHMMA_03159 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
IICHHMMA_03160 3.8e-87 ysxD
IICHHMMA_03161 4.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IICHHMMA_03162 1e-145 hemX O cytochrome C
IICHHMMA_03163 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IICHHMMA_03164 6.6e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IICHHMMA_03165 5.1e-184 hemB 4.2.1.24 H Belongs to the ALAD family
IICHHMMA_03166 2.3e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IICHHMMA_03167 4.7e-135 spoVID M stage VI sporulation protein D
IICHHMMA_03168 2.8e-196 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IICHHMMA_03169 4.7e-25
IICHHMMA_03170 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IICHHMMA_03171 1.4e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IICHHMMA_03172 3.3e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IICHHMMA_03173 5.7e-138 spoIIB S Sporulation related domain
IICHHMMA_03174 2.3e-99 maf D septum formation protein Maf
IICHHMMA_03175 1.8e-127 radC E Belongs to the UPF0758 family
IICHHMMA_03176 4e-184 mreB D Rod shape-determining protein MreB
IICHHMMA_03177 3.6e-157 mreC M Involved in formation and maintenance of cell shape
IICHHMMA_03178 5.4e-84 mreD M shape-determining protein
IICHHMMA_03179 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IICHHMMA_03180 1.2e-141 minD D Belongs to the ParA family
IICHHMMA_03181 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
IICHHMMA_03182 1.2e-160 spoIVFB S Stage IV sporulation protein
IICHHMMA_03183 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
IICHHMMA_03184 1.2e-55 ysxB J ribosomal protein
IICHHMMA_03185 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IICHHMMA_03186 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
IICHHMMA_03187 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IICHHMMA_03188 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
IICHHMMA_03189 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
IICHHMMA_03190 1.3e-93 niaR S small molecule binding protein (contains 3H domain)
IICHHMMA_03191 1.9e-222 nifS 2.8.1.7 E Cysteine desulfurase
IICHHMMA_03192 1.6e-296 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
IICHHMMA_03193 1.7e-151 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
IICHHMMA_03194 5.3e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IICHHMMA_03195 1.6e-126 safA M spore coat assembly protein SafA
IICHHMMA_03196 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IICHHMMA_03198 3.7e-93 bofC S BofC C-terminal domain
IICHHMMA_03199 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IICHHMMA_03200 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IICHHMMA_03201 1.6e-20 yrzS S Protein of unknown function (DUF2905)
IICHHMMA_03202 3.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IICHHMMA_03203 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IICHHMMA_03204 2.5e-37 yajC U Preprotein translocase subunit YajC
IICHHMMA_03205 2.4e-60 yrzE S Protein of unknown function (DUF3792)
IICHHMMA_03206 9.5e-110 yrbG S membrane
IICHHMMA_03207 2.1e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IICHHMMA_03208 1.3e-50 yrzD S Post-transcriptional regulator
IICHHMMA_03209 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IICHHMMA_03210 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
IICHHMMA_03211 5.7e-47 yrvD S Lipopolysaccharide assembly protein A domain
IICHHMMA_03212 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IICHHMMA_03213 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IICHHMMA_03214 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IICHHMMA_03215 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IICHHMMA_03216 1.6e-272 lytH 3.5.1.28 M COG3103 SH3 domain protein
IICHHMMA_03219 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
IICHHMMA_03220 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IICHHMMA_03221 3.7e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IICHHMMA_03222 8.2e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IICHHMMA_03223 7.8e-64 cymR K Transcriptional regulator
IICHHMMA_03224 1.1e-211 iscS 2.8.1.7 E Cysteine desulfurase
IICHHMMA_03225 2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IICHHMMA_03226 1.7e-18 S COG0457 FOG TPR repeat
IICHHMMA_03227 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IICHHMMA_03228 6.9e-83 yrrD S protein conserved in bacteria
IICHHMMA_03229 2.9e-30 yrzR
IICHHMMA_03230 2.1e-08 S Protein of unknown function (DUF3918)
IICHHMMA_03231 1.7e-106 glnP P ABC transporter
IICHHMMA_03232 1.2e-107 gluC P ABC transporter
IICHHMMA_03233 2.1e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
IICHHMMA_03234 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IICHHMMA_03235 9.2e-163 yrrI S AI-2E family transporter
IICHHMMA_03236 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IICHHMMA_03237 1.7e-41 yrzL S Belongs to the UPF0297 family
IICHHMMA_03238 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IICHHMMA_03239 7.1e-46 yrzB S Belongs to the UPF0473 family
IICHHMMA_03240 6.9e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IICHHMMA_03241 1.8e-116 yrrM 2.1.1.104 S O-methyltransferase
IICHHMMA_03242 1.1e-172 yegQ O Peptidase U32
IICHHMMA_03243 1.6e-246 yegQ O COG0826 Collagenase and related proteases
IICHHMMA_03244 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
IICHHMMA_03245 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IICHHMMA_03246 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
IICHHMMA_03247 3.1e-69 yrrS S Protein of unknown function (DUF1510)
IICHHMMA_03248 4.1e-27 yrzA S Protein of unknown function (DUF2536)
IICHHMMA_03249 1e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
IICHHMMA_03250 2.1e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IICHHMMA_03251 6.8e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
IICHHMMA_03252 1.8e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IICHHMMA_03253 1.3e-34 yrhC S YrhC-like protein
IICHHMMA_03254 7e-81 yrhD S Protein of unknown function (DUF1641)
IICHHMMA_03255 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
IICHHMMA_03256 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
IICHHMMA_03257 8e-143 focA P Formate nitrite
IICHHMMA_03259 7.4e-92 yrhH Q methyltransferase
IICHHMMA_03260 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
IICHHMMA_03261 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IICHHMMA_03262 6.5e-213 ynfM EGP Major facilitator Superfamily
IICHHMMA_03263 4.1e-164 yybE K Transcriptional regulator
IICHHMMA_03264 8.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IICHHMMA_03265 3.2e-180 romA S Beta-lactamase superfamily domain
IICHHMMA_03266 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
IICHHMMA_03267 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
IICHHMMA_03268 3.4e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
IICHHMMA_03269 4.5e-129 glvR K Helix-turn-helix domain, rpiR family
IICHHMMA_03270 4.6e-146 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
IICHHMMA_03271 1.9e-144 S hydrolase
IICHHMMA_03273 2.9e-90 yrdA S DinB family
IICHHMMA_03274 5.1e-82 yyaR K Acetyltransferase (GNAT) domain
IICHHMMA_03275 3.9e-222 tetL EGP Major facilitator Superfamily
IICHHMMA_03276 9.9e-97 adk 2.7.4.3 F adenylate kinase activity
IICHHMMA_03277 2.6e-68 ydeE K AraC family transcriptional regulator
IICHHMMA_03278 7.2e-92 K Transcriptional regulator PadR-like family
IICHHMMA_03279 6.6e-153 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
IICHHMMA_03280 3.3e-20 yqaO S Phage-like element PBSX protein XtrA
IICHHMMA_03282 5e-11 L Transposase
IICHHMMA_03283 4.3e-35 L Transposase
IICHHMMA_03284 3.9e-46
IICHHMMA_03285 2.3e-10 yqaS L DNA packaging
IICHHMMA_03286 3.2e-69 K MerR family transcriptional regulator
IICHHMMA_03287 1.1e-137 yvgN 1.1.1.346 S Reductase
IICHHMMA_03288 5e-109 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IICHHMMA_03289 1.9e-24 xkdS S Protein of unknown function (DUF2634)
IICHHMMA_03290 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IICHHMMA_03291 5.1e-213 EGP Major facilitator Superfamily
IICHHMMA_03293 3.6e-106 yqeD S SNARE associated Golgi protein
IICHHMMA_03294 8.4e-139 3.5.1.104 G Polysaccharide deacetylase
IICHHMMA_03295 1.1e-138 yqeF E GDSL-like Lipase/Acylhydrolase
IICHHMMA_03297 2e-94 yqeG S hydrolase of the HAD superfamily
IICHHMMA_03298 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IICHHMMA_03299 2.1e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IICHHMMA_03300 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
IICHHMMA_03301 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IICHHMMA_03302 2.1e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IICHHMMA_03303 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IICHHMMA_03304 4.9e-139 yqeM Q Methyltransferase
IICHHMMA_03305 3.8e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IICHHMMA_03306 7.3e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IICHHMMA_03307 8e-105 comEB 3.5.4.12 F ComE operon protein 2
IICHHMMA_03308 0.0 comEC S Competence protein ComEC
IICHHMMA_03309 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
IICHHMMA_03310 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
IICHHMMA_03311 8.6e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IICHHMMA_03312 2.4e-220 spoIIP M stage II sporulation protein P
IICHHMMA_03313 3.8e-54 yqxA S Protein of unknown function (DUF3679)
IICHHMMA_03314 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IICHHMMA_03315 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
IICHHMMA_03316 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IICHHMMA_03317 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IICHHMMA_03318 0.0 dnaK O Heat shock 70 kDa protein
IICHHMMA_03319 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IICHHMMA_03320 6.6e-173 prmA J Methylates ribosomal protein L11
IICHHMMA_03321 3.9e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IICHHMMA_03322 1.3e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
IICHHMMA_03323 1.3e-155 yqeW P COG1283 Na phosphate symporter
IICHHMMA_03324 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IICHHMMA_03325 8e-68 yqeY S Yqey-like protein
IICHHMMA_03326 5.7e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
IICHHMMA_03327 3.8e-118 yqfA S UPF0365 protein
IICHHMMA_03328 3.9e-51 yqfB
IICHHMMA_03329 9.3e-46 yqfC S sporulation protein YqfC
IICHHMMA_03330 2.8e-213 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
IICHHMMA_03331 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
IICHHMMA_03332 0.0 yqfF S membrane-associated HD superfamily hydrolase
IICHHMMA_03333 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IICHHMMA_03334 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IICHHMMA_03335 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IICHHMMA_03336 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IICHHMMA_03337 1.8e-16 S YqzL-like protein
IICHHMMA_03338 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
IICHHMMA_03339 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IICHHMMA_03340 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IICHHMMA_03341 4.5e-112 ccpN K CBS domain
IICHHMMA_03342 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IICHHMMA_03343 6.1e-88 yaiI S Belongs to the UPF0178 family
IICHHMMA_03344 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IICHHMMA_03345 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IICHHMMA_03346 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
IICHHMMA_03347 9.9e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
IICHHMMA_03348 1.2e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IICHHMMA_03349 6.5e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IICHHMMA_03350 8.4e-48 yqfQ S YqfQ-like protein
IICHHMMA_03351 6.3e-246 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IICHHMMA_03352 5.4e-164 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IICHHMMA_03353 1.6e-36 yqfT S Protein of unknown function (DUF2624)
IICHHMMA_03354 5.3e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IICHHMMA_03355 2.9e-72 zur P Belongs to the Fur family
IICHHMMA_03356 9.3e-109 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
IICHHMMA_03357 2.3e-52 yqfX S membrane
IICHHMMA_03358 4.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IICHHMMA_03359 3.1e-47 yqfZ M LysM domain
IICHHMMA_03360 4.8e-129 yqgB S Protein of unknown function (DUF1189)
IICHHMMA_03361 9.3e-70 yqgC S protein conserved in bacteria
IICHHMMA_03362 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
IICHHMMA_03363 2e-228 yqgE EGP Major facilitator superfamily
IICHHMMA_03364 0.0 pbpA 3.4.16.4 M penicillin-binding protein
IICHHMMA_03365 7.6e-158 pstS P Phosphate
IICHHMMA_03366 5.2e-154 pstC P probably responsible for the translocation of the substrate across the membrane
IICHHMMA_03367 5.3e-156 pstA P Phosphate transport system permease
IICHHMMA_03368 4.3e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IICHHMMA_03369 2.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IICHHMMA_03370 3.2e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IICHHMMA_03371 1.2e-50 yqzD
IICHHMMA_03372 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IICHHMMA_03373 4.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IICHHMMA_03374 4e-07 yqgO
IICHHMMA_03375 4.1e-232 nhaC C Na H antiporter
IICHHMMA_03376 6.5e-28 yqgQ S Protein conserved in bacteria
IICHHMMA_03377 2.2e-179 glcK 2.7.1.2 G Glucokinase
IICHHMMA_03378 7.4e-219 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
IICHHMMA_03379 7.8e-199 yqgU
IICHHMMA_03380 6.9e-50 yqgV S Thiamine-binding protein
IICHHMMA_03381 5.4e-20 yqgW S Protein of unknown function (DUF2759)
IICHHMMA_03382 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IICHHMMA_03383 3.1e-37 yqgY S Protein of unknown function (DUF2626)
IICHHMMA_03384 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
IICHHMMA_03386 1.6e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IICHHMMA_03387 1.8e-237 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IICHHMMA_03388 1.2e-185 corA P Mg2 transporter protein
IICHHMMA_03389 6.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IICHHMMA_03390 2.4e-184 comGB NU COG1459 Type II secretory pathway, component PulF
IICHHMMA_03391 8.9e-50 comGC U Required for transformation and DNA binding
IICHHMMA_03392 2.6e-71 gspH NU Tfp pilus assembly protein FimT
IICHHMMA_03393 1.2e-20 comGE
IICHHMMA_03394 4.8e-64 comGF U Putative Competence protein ComGF
IICHHMMA_03395 1e-60 S ComG operon protein 7
IICHHMMA_03396 2.3e-26 yqzE S YqzE-like protein
IICHHMMA_03397 1.1e-53 yqzG S Protein of unknown function (DUF3889)
IICHHMMA_03398 4.2e-121 yqxM
IICHHMMA_03399 3.5e-71 sipW 3.4.21.89 U Signal peptidase
IICHHMMA_03400 3.3e-141 tasA S Cell division protein FtsN
IICHHMMA_03401 7.8e-55 sinR K transcriptional
IICHHMMA_03402 5.2e-23 sinI S Anti-repressor SinI
IICHHMMA_03403 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
IICHHMMA_03404 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IICHHMMA_03405 7.4e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
IICHHMMA_03406 8.7e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IICHHMMA_03407 2.7e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IICHHMMA_03408 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
IICHHMMA_03409 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IICHHMMA_03410 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IICHHMMA_03411 2e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
IICHHMMA_03412 4.5e-62 yqhP
IICHHMMA_03413 8e-174 yqhQ S Protein of unknown function (DUF1385)
IICHHMMA_03414 3.7e-88 yqhR S Conserved membrane protein YqhR
IICHHMMA_03415 9.5e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IICHHMMA_03416 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IICHHMMA_03417 1.1e-35 yqhV S Protein of unknown function (DUF2619)
IICHHMMA_03418 2.6e-169 spoIIIAA S stage III sporulation protein AA
IICHHMMA_03419 1.6e-83 spoIIIAB S Stage III sporulation protein
IICHHMMA_03420 7.6e-29 spoIIIAC S stage III sporulation protein AC
IICHHMMA_03421 4.5e-47 spoIIIAD S Stage III sporulation protein AD
IICHHMMA_03422 6.3e-200 spoIIIAE S stage III sporulation protein AE
IICHHMMA_03423 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
IICHHMMA_03424 3.2e-116 spoIIIAG S stage III sporulation protein AG
IICHHMMA_03425 2.5e-62 spoIIIAH S SpoIIIAH-like protein
IICHHMMA_03426 6.4e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IICHHMMA_03427 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IICHHMMA_03428 8.1e-67 yqhY S protein conserved in bacteria
IICHHMMA_03429 2.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IICHHMMA_03430 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IICHHMMA_03431 7.9e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IICHHMMA_03432 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IICHHMMA_03433 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IICHHMMA_03434 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IICHHMMA_03435 1.3e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
IICHHMMA_03436 3.9e-78 argR K Regulates arginine biosynthesis genes
IICHHMMA_03437 1.3e-304 recN L May be involved in recombinational repair of damaged DNA
IICHHMMA_03438 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
IICHHMMA_03439 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IICHHMMA_03440 2e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IICHHMMA_03443 9.2e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IICHHMMA_03445 1.2e-112 K Protein of unknown function (DUF1232)
IICHHMMA_03446 2e-101 ytaF P Probably functions as a manganese efflux pump
IICHHMMA_03447 5.5e-17
IICHHMMA_03448 8.8e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
IICHHMMA_03449 5.6e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IICHHMMA_03450 1.8e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
IICHHMMA_03451 9.7e-155 hbdA 1.1.1.157 I Dehydrogenase
IICHHMMA_03452 2.7e-205 mmgC I acyl-CoA dehydrogenase
IICHHMMA_03453 1.9e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
IICHHMMA_03454 7.8e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
IICHHMMA_03455 1.8e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IICHHMMA_03456 3.2e-34 yqzF S Protein of unknown function (DUF2627)
IICHHMMA_03457 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
IICHHMMA_03458 1.8e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
IICHHMMA_03459 6.9e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
IICHHMMA_03460 6.4e-207 buk 2.7.2.7 C Belongs to the acetokinase family
IICHHMMA_03461 1.3e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IICHHMMA_03462 9.5e-162 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IICHHMMA_03463 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IICHHMMA_03464 6.3e-203 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IICHHMMA_03465 2.3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IICHHMMA_03466 1e-75 yqiW S Belongs to the UPF0403 family
IICHHMMA_03467 2.2e-134 artP ET Belongs to the bacterial solute-binding protein 3 family
IICHHMMA_03468 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
IICHHMMA_03469 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IICHHMMA_03470 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
IICHHMMA_03471 1.1e-95 yqjB S protein conserved in bacteria
IICHHMMA_03473 4.2e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
IICHHMMA_03474 7.7e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IICHHMMA_03475 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
IICHHMMA_03476 1.7e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IICHHMMA_03477 2.4e-25 yqzJ
IICHHMMA_03478 4.7e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IICHHMMA_03479 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IICHHMMA_03480 1.2e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IICHHMMA_03481 1.6e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IICHHMMA_03482 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IICHHMMA_03483 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IICHHMMA_03484 1.1e-50 S GlpM protein
IICHHMMA_03485 9e-164 K LysR substrate binding domain
IICHHMMA_03486 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
IICHHMMA_03487 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IICHHMMA_03490 1.2e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IICHHMMA_03491 1.1e-127 IQ reductase
IICHHMMA_03492 3.3e-23 M1-820 Q Collagen triple helix repeat (20 copies)
IICHHMMA_03493 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
IICHHMMA_03494 5.7e-273 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IICHHMMA_03495 1.2e-118 citT T response regulator
IICHHMMA_03496 3.5e-177 yflP S Tripartite tricarboxylate transporter family receptor
IICHHMMA_03497 7.2e-226 citM C Citrate transporter
IICHHMMA_03498 1.9e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
IICHHMMA_03499 3.3e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IICHHMMA_03500 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IICHHMMA_03501 4.4e-123 yflK S protein conserved in bacteria
IICHHMMA_03502 1.5e-14 yflJ S Protein of unknown function (DUF2639)
IICHHMMA_03503 7e-19 yflI
IICHHMMA_03504 3.1e-50 yflH S Protein of unknown function (DUF3243)
IICHHMMA_03505 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
IICHHMMA_03506 2.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IICHHMMA_03507 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
IICHHMMA_03508 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IICHHMMA_03509 7.8e-64 yhdN S Domain of unknown function (DUF1992)
IICHHMMA_03510 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
IICHHMMA_03511 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
IICHHMMA_03512 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
IICHHMMA_03513 1.2e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IICHHMMA_03514 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IICHHMMA_03515 5e-128 treR K transcriptional
IICHHMMA_03516 3.4e-123 yfkO C nitroreductase
IICHHMMA_03517 1.8e-123 yibF S YibE/F-like protein
IICHHMMA_03518 1.5e-198 yibE S YibE/F-like protein
IICHHMMA_03519 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
IICHHMMA_03520 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
IICHHMMA_03521 1.1e-184 K helix_turn _helix lactose operon repressor
IICHHMMA_03522 2e-163 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IICHHMMA_03523 5.8e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IICHHMMA_03524 4.3e-193 ydiM EGP Major facilitator Superfamily
IICHHMMA_03525 2.7e-29 yfkK S Belongs to the UPF0435 family
IICHHMMA_03526 2e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IICHHMMA_03527 3.5e-52 yfkI S gas vesicle protein
IICHHMMA_03528 7.6e-144 yihY S Belongs to the UPF0761 family
IICHHMMA_03529 2.5e-07
IICHHMMA_03530 7.2e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
IICHHMMA_03531 6.5e-185 cax P COG0387 Ca2 H antiporter
IICHHMMA_03532 1.6e-143 yfkD S YfkD-like protein
IICHHMMA_03533 1e-145 yfkC M Mechanosensitive ion channel
IICHHMMA_03534 7.3e-219 yfkA S YfkB-like domain
IICHHMMA_03535 4.9e-27 yfjT
IICHHMMA_03536 2.6e-154 pdaA G deacetylase
IICHHMMA_03537 4e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IICHHMMA_03538 1.8e-31
IICHHMMA_03539 8.5e-184 corA P Mediates influx of magnesium ions
IICHHMMA_03540 1.3e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IICHHMMA_03541 1.6e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IICHHMMA_03542 3.9e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IICHHMMA_03543 1.5e-88 yfjM S Psort location Cytoplasmic, score
IICHHMMA_03544 8.3e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IICHHMMA_03545 1.8e-187 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IICHHMMA_03546 4.9e-213 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IICHHMMA_03547 2.9e-249 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IICHHMMA_03548 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
IICHHMMA_03549 4.2e-15 sspH S Belongs to the SspH family
IICHHMMA_03550 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IICHHMMA_03551 1.5e-138 glvR F Helix-turn-helix domain, rpiR family
IICHHMMA_03552 5.2e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IICHHMMA_03553 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
IICHHMMA_03554 2e-308 yfiB3 V ABC transporter
IICHHMMA_03555 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
IICHHMMA_03556 2e-62 mhqP S DoxX
IICHHMMA_03557 1e-159 yfiE 1.13.11.2 S glyoxalase
IICHHMMA_03558 3.6e-166 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IICHHMMA_03559 6.6e-96 padR K transcriptional
IICHHMMA_03560 3.6e-111 1.6.5.2 S NADPH-dependent FMN reductase
IICHHMMA_03561 1.9e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IICHHMMA_03562 1.9e-19 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IICHHMMA_03563 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
IICHHMMA_03564 4.5e-45 yrdF K ribonuclease inhibitor
IICHHMMA_03565 1.5e-97 yfiT S Belongs to the metal hydrolase YfiT family
IICHHMMA_03566 2.7e-283 yfiU EGP Major facilitator Superfamily
IICHHMMA_03567 6.2e-82 yfiV K transcriptional
IICHHMMA_03568 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IICHHMMA_03569 4.6e-160 yfhB 5.3.3.17 S PhzF family
IICHHMMA_03570 5.7e-106 yfhC C nitroreductase
IICHHMMA_03571 2.1e-25 yfhD S YfhD-like protein
IICHHMMA_03573 3.7e-165 yfhF S nucleoside-diphosphate sugar epimerase
IICHHMMA_03574 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
IICHHMMA_03575 7.3e-52 yfhH S Protein of unknown function (DUF1811)
IICHHMMA_03576 1.1e-204 yfhI EGP Major facilitator Superfamily
IICHHMMA_03578 5.3e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
IICHHMMA_03579 2.2e-44 yfhJ S WVELL protein
IICHHMMA_03580 2.2e-93 batE T Bacterial SH3 domain homologues
IICHHMMA_03581 2.2e-33 yfhL S SdpI/YhfL protein family
IICHHMMA_03582 1.7e-170 yfhM S Alpha/beta hydrolase family
IICHHMMA_03583 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IICHHMMA_03584 0.0 yfhO S Bacterial membrane protein YfhO
IICHHMMA_03585 1.8e-184 yfhP S membrane-bound metal-dependent
IICHHMMA_03586 1.7e-207 mutY L A G-specific
IICHHMMA_03587 3.1e-36 yfhS
IICHHMMA_03588 2.2e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IICHHMMA_03590 1.5e-37 ygaB S YgaB-like protein
IICHHMMA_03591 2.2e-104 ygaC J Belongs to the UPF0374 family
IICHHMMA_03592 4.5e-300 ygaD V ABC transporter
IICHHMMA_03593 2.7e-178 ygaE S Membrane
IICHHMMA_03594 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IICHHMMA_03595 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
IICHHMMA_03596 1.8e-80 perR P Belongs to the Fur family
IICHHMMA_03597 3.3e-56 ygzB S UPF0295 protein
IICHHMMA_03598 1.1e-164 ygxA S Nucleotidyltransferase-like
IICHHMMA_03599 3.5e-39 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_03600 2.2e-78 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICHHMMA_03601 9.1e-62 hxlR K transcriptional
IICHHMMA_03602 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
IICHHMMA_03603 5.6e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
IICHHMMA_03604 7.1e-77 nucA M Deoxyribonuclease NucA/NucB
IICHHMMA_03605 5.1e-66 nin S Competence protein J (ComJ)
IICHHMMA_03606 7.1e-15 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IICHHMMA_03607 1.3e-48 S Protein of unknown function (DUF2680)
IICHHMMA_03608 4.8e-73 yckC S membrane
IICHHMMA_03609 2.3e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IICHHMMA_03610 1.3e-226 yciC S GTPases (G3E family)
IICHHMMA_03611 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IICHHMMA_03612 5.1e-56 nirD 1.7.1.15 P Nitrite reductase
IICHHMMA_03613 5.8e-277 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IICHHMMA_03614 3.8e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IICHHMMA_03615 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
IICHHMMA_03616 7.6e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IICHHMMA_03617 1.3e-290 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IICHHMMA_03618 2.3e-170 ycgM E Proline dehydrogenase
IICHHMMA_03619 1.3e-145 ycgL S Predicted nucleotidyltransferase
IICHHMMA_03620 6.5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
IICHHMMA_03621 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IICHHMMA_03622 4.8e-222 G COG0477 Permeases of the major facilitator superfamily
IICHHMMA_03623 1.9e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
IICHHMMA_03624 6.2e-108 tmrB S AAA domain
IICHHMMA_03626 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IICHHMMA_03627 7.6e-114 ycgI S Domain of unknown function (DUF1989)
IICHHMMA_03628 6.4e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
IICHHMMA_03629 5.8e-151 yqcI S YqcI/YcgG family
IICHHMMA_03630 4.7e-114 ycgF E Lysine exporter protein LysE YggA
IICHHMMA_03631 3.1e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
IICHHMMA_03632 1.8e-260 mdr EGP Major facilitator Superfamily
IICHHMMA_03633 1.8e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IICHHMMA_03634 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
IICHHMMA_03635 1.2e-80 ycgB
IICHHMMA_03636 5.5e-227 ycgA S Membrane
IICHHMMA_03637 2.8e-210 amhX S amidohydrolase
IICHHMMA_03638 3.1e-164 opuAC E glycine betaine
IICHHMMA_03639 3.7e-138 opuAB P glycine betaine
IICHHMMA_03640 8.7e-229 proV 3.6.3.32 E glycine betaine
IICHHMMA_03641 3.4e-198 naiP P Uncharacterised MFS-type transporter YbfB
IICHHMMA_03642 5.1e-193 yceH P Belongs to the TelA family
IICHHMMA_03643 0.0 yceG S Putative component of 'biosynthetic module'
IICHHMMA_03644 9.7e-138 terC P Protein of unknown function (DUF475)
IICHHMMA_03645 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
IICHHMMA_03646 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
IICHHMMA_03647 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
IICHHMMA_03648 1.6e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IICHHMMA_03649 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IICHHMMA_03650 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IICHHMMA_03651 2.3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
IICHHMMA_03652 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
IICHHMMA_03653 2e-138 IQ Enoyl-(Acyl carrier protein) reductase
IICHHMMA_03654 1e-188 S response regulator aspartate phosphatase
IICHHMMA_03655 3.4e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
IICHHMMA_03656 7.4e-266 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
IICHHMMA_03657 2.1e-255 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
IICHHMMA_03658 1.5e-175 ycdA S Domain of unknown function (DUF5105)
IICHHMMA_03659 2.1e-171 yccK C Aldo keto reductase
IICHHMMA_03660 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
IICHHMMA_03661 1.4e-113 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
IICHHMMA_03662 7.8e-197 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IICHHMMA_03663 1.3e-99 yxaF K Transcriptional regulator
IICHHMMA_03664 1e-241 lmrB EGP the major facilitator superfamily
IICHHMMA_03665 1.2e-208 ycbU E Selenocysteine lyase
IICHHMMA_03666 2.9e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IICHHMMA_03667 6.4e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IICHHMMA_03668 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IICHHMMA_03669 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
IICHHMMA_03670 5.3e-77 sleB 3.5.1.28 M Cell wall
IICHHMMA_03671 5.6e-62 ycbP S Protein of unknown function (DUF2512)
IICHHMMA_03672 6.5e-54 traF CO Thioredoxin
IICHHMMA_03673 4.4e-62 mhqP S DoxX
IICHHMMA_03674 4.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
IICHHMMA_03675 1.3e-108 ydfN C nitroreductase
IICHHMMA_03676 2e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IICHHMMA_03677 1.8e-25 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
IICHHMMA_03678 1.2e-126 ycbJ S Macrolide 2'-phosphotransferase
IICHHMMA_03679 9.7e-172 glnL T Regulator
IICHHMMA_03680 7.4e-207 phoQ 2.7.13.3 T Histidine kinase
IICHHMMA_03681 4.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
IICHHMMA_03682 1.7e-257 agcS E Sodium alanine symporter
IICHHMMA_03683 1.6e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
IICHHMMA_03684 5.2e-257 mmuP E amino acid
IICHHMMA_03685 1.9e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IICHHMMA_03686 2.5e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IICHHMMA_03687 1.2e-190 yceA S Belongs to the UPF0176 family
IICHHMMA_03688 6.1e-42 ybfN
IICHHMMA_03689 2.5e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IICHHMMA_03690 1.9e-86 ybfM S SNARE associated Golgi protein
IICHHMMA_03691 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IICHHMMA_03692 4e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IICHHMMA_03693 2.2e-196 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
IICHHMMA_03694 1.2e-82 K Helix-turn-helix XRE-family like proteins
IICHHMMA_03695 2e-31
IICHHMMA_03696 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
IICHHMMA_03698 3.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
IICHHMMA_03699 1e-16 S Protein of unknown function (DUF2651)
IICHHMMA_03700 1.7e-259 glpT G -transporter
IICHHMMA_03701 2.8e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IICHHMMA_03702 3e-16 S Protein of unknown function (DUF2651)
IICHHMMA_03703 6.3e-38
IICHHMMA_03704 9.6e-09
IICHHMMA_03705 2.8e-291 ybeC E amino acid
IICHHMMA_03706 9.2e-40 ybyB
IICHHMMA_03707 3.1e-106 yqeB
IICHHMMA_03708 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
IICHHMMA_03709 7.2e-75 S Domain of unknown function (DUF4879)
IICHHMMA_03710 2.3e-49 crtF 2.1.1.210 Q PFAM O-methyltransferase
IICHHMMA_03711 0.0 Q TIGRFAM amino acid adenylation domain
IICHHMMA_03712 2.9e-98 Q Flavin containing amine oxidoreductase
IICHHMMA_03713 0.0 Q Polyketide synthase modules and related proteins
IICHHMMA_03714 0.0 Q Beta-ketoacyl synthase
IICHHMMA_03715 3.9e-120 fabD 2.3.1.39 I PFAM Acyl transferase
IICHHMMA_03716 0.0 srfAC Q TIGRFAM amino acid adenylation domain
IICHHMMA_03717 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
IICHHMMA_03718 3.6e-32 yaaL S Protein of unknown function (DUF2508)
IICHHMMA_03719 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IICHHMMA_03720 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IICHHMMA_03721 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IICHHMMA_03722 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IICHHMMA_03723 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
IICHHMMA_03724 3.8e-211 yaaH M Glycoside Hydrolase Family
IICHHMMA_03725 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
IICHHMMA_03726 1.6e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
IICHHMMA_03727 1.3e-09
IICHHMMA_03728 5.4e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IICHHMMA_03729 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IICHHMMA_03730 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IICHHMMA_03731 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IICHHMMA_03732 1.1e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IICHHMMA_03733 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IICHHMMA_03734 2.4e-181 yaaC S YaaC-like Protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)