ORF_ID e_value Gene_name EC_number CAZy COGs Description
EFMJKMEB_00001 2e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
EFMJKMEB_00002 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EFMJKMEB_00003 6.6e-61 EGP Major facilitator Superfamily
EFMJKMEB_00004 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
EFMJKMEB_00005 1.1e-212 pqqE C radical SAM domain protein
EFMJKMEB_00008 2e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EFMJKMEB_00009 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EFMJKMEB_00011 1.8e-136 IQ Acetoin reductase
EFMJKMEB_00012 2.9e-92 ET Bacterial periplasmic substrate-binding proteins
EFMJKMEB_00013 4.4e-45 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EFMJKMEB_00014 5e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EFMJKMEB_00015 1e-34 XK27_05470 E Methionine synthase
EFMJKMEB_00016 1.4e-77 XK27_05470 E Methionine synthase
EFMJKMEB_00017 9.6e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EFMJKMEB_00018 3.4e-250 T PhoQ Sensor
EFMJKMEB_00019 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFMJKMEB_00020 3.6e-154 S TraX protein
EFMJKMEB_00021 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EFMJKMEB_00022 3.5e-157 dprA LU DNA protecting protein DprA
EFMJKMEB_00023 3.5e-166 GK ROK family
EFMJKMEB_00024 2.6e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFMJKMEB_00025 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EFMJKMEB_00026 8.1e-128 K DNA-binding helix-turn-helix protein
EFMJKMEB_00027 3e-90 niaR S small molecule binding protein (contains 3H domain)
EFMJKMEB_00028 3.1e-87 niaX
EFMJKMEB_00029 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EFMJKMEB_00030 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EFMJKMEB_00031 2e-126 gntR1 K transcriptional
EFMJKMEB_00032 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EFMJKMEB_00033 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
EFMJKMEB_00034 0.0 res_1 3.1.21.5 S Type III restriction
EFMJKMEB_00035 3e-21
EFMJKMEB_00037 5.7e-110 adhP 1.1.1.1 C alcohol dehydrogenase
EFMJKMEB_00038 5.6e-61 adhP 1.1.1.1 C alcohol dehydrogenase
EFMJKMEB_00039 2.1e-07
EFMJKMEB_00040 1.6e-65 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFMJKMEB_00041 1.1e-31 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFMJKMEB_00042 2.1e-73 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFMJKMEB_00043 1.2e-157 aatB ET ABC transporter substrate-binding protein
EFMJKMEB_00044 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
EFMJKMEB_00045 5.3e-105 artQ P ABC transporter (Permease
EFMJKMEB_00046 6.1e-57 phnA P Alkylphosphonate utilization operon protein PhnA
EFMJKMEB_00047 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EFMJKMEB_00048 2.2e-165 cpsY K Transcriptional regulator
EFMJKMEB_00049 4.2e-20 L transposase activity
EFMJKMEB_00050 1.6e-118 mur1 NU muramidase
EFMJKMEB_00051 1.5e-170 yeiH S Membrane
EFMJKMEB_00052 1.7e-08
EFMJKMEB_00053 6.2e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
EFMJKMEB_00054 6.4e-58 XK27_10720 D peptidase activity
EFMJKMEB_00055 2.4e-57 pepD E Dipeptidase
EFMJKMEB_00057 8e-102
EFMJKMEB_00058 5.6e-101 L Phage integrase family
EFMJKMEB_00059 1.5e-147
EFMJKMEB_00060 7.4e-55 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
EFMJKMEB_00061 2.3e-93 hsdM 2.1.1.72 V type I restriction-modification system
EFMJKMEB_00062 1.4e-151 glcU U Glucose uptake
EFMJKMEB_00063 2.3e-48 L transposition
EFMJKMEB_00064 1.3e-31 L Integrase core domain protein
EFMJKMEB_00067 5.3e-16
EFMJKMEB_00068 1.7e-54 S TM2 domain
EFMJKMEB_00069 3.1e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EFMJKMEB_00070 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EFMJKMEB_00071 2.2e-24 secE U Belongs to the SecE SEC61-gamma family
EFMJKMEB_00072 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
EFMJKMEB_00073 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
EFMJKMEB_00074 4e-47 cof Q phosphatase activity
EFMJKMEB_00075 2.1e-35 cof Q phosphatase activity
EFMJKMEB_00076 1.9e-98 glcR K transcriptional regulator (DeoR family)
EFMJKMEB_00077 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EFMJKMEB_00078 3.5e-71 K transcriptional
EFMJKMEB_00079 2.2e-232 S COG1073 Hydrolases of the alpha beta superfamily
EFMJKMEB_00080 2.7e-274 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EFMJKMEB_00081 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EFMJKMEB_00082 1.1e-69 yhaI L Membrane
EFMJKMEB_00083 5.4e-253 pepC 3.4.22.40 E aminopeptidase
EFMJKMEB_00084 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EFMJKMEB_00085 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EFMJKMEB_00086 3.1e-95 ypsA S Belongs to the UPF0398 family
EFMJKMEB_00087 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EFMJKMEB_00088 1.9e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EFMJKMEB_00089 1.7e-305 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
EFMJKMEB_00090 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
EFMJKMEB_00091 2.5e-23
EFMJKMEB_00092 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EFMJKMEB_00093 3.3e-80 XK27_09675 K -acetyltransferase
EFMJKMEB_00094 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EFMJKMEB_00095 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EFMJKMEB_00096 2.6e-88 L Integrase core domain protein
EFMJKMEB_00097 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFMJKMEB_00098 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EFMJKMEB_00099 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFMJKMEB_00100 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
EFMJKMEB_00101 2.9e-93 ybhL S Belongs to the BI1 family
EFMJKMEB_00104 8.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EFMJKMEB_00105 4.5e-89 K transcriptional regulator
EFMJKMEB_00106 7.6e-36 yneF S UPF0154 protein
EFMJKMEB_00107 1.9e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EFMJKMEB_00108 8.7e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EFMJKMEB_00109 1.7e-98 XK27_09740 S Phosphoesterase
EFMJKMEB_00110 2.7e-85 ykuL S CBS domain
EFMJKMEB_00111 2.8e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
EFMJKMEB_00112 1.5e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EFMJKMEB_00113 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EFMJKMEB_00114 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EFMJKMEB_00115 8e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EFMJKMEB_00116 1.4e-254 trkH P Cation transport protein
EFMJKMEB_00117 1.4e-245 trkA P Potassium transporter peripheral membrane component
EFMJKMEB_00118 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EFMJKMEB_00119 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EFMJKMEB_00120 6.5e-111 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
EFMJKMEB_00121 5.6e-161 K sequence-specific DNA binding
EFMJKMEB_00122 2.1e-32 V protein secretion by the type I secretion system
EFMJKMEB_00123 5.5e-105 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EFMJKMEB_00124 4.4e-56 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EFMJKMEB_00125 5.6e-161 L Transposase
EFMJKMEB_00126 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EFMJKMEB_00127 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EFMJKMEB_00128 5.5e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EFMJKMEB_00129 1.5e-239 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
EFMJKMEB_00131 7.9e-61 divIC D Septum formation initiator
EFMJKMEB_00132 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EFMJKMEB_00133 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EFMJKMEB_00134 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EFMJKMEB_00135 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EFMJKMEB_00136 4.1e-29 yyzM S Protein conserved in bacteria
EFMJKMEB_00137 2.4e-201 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EFMJKMEB_00138 4.8e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EFMJKMEB_00139 1e-134 parB K Belongs to the ParB family
EFMJKMEB_00140 1.1e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
EFMJKMEB_00141 2.5e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EFMJKMEB_00142 1.4e-119 yoaK S Psort location CytoplasmicMembrane, score
EFMJKMEB_00146 0.0 XK27_10405 S Bacterial membrane protein YfhO
EFMJKMEB_00147 6.7e-306 ybiT S abc transporter atp-binding protein
EFMJKMEB_00148 5.4e-153 yvjA S membrane
EFMJKMEB_00149 1.4e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EFMJKMEB_00150 4.7e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EFMJKMEB_00151 2.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EFMJKMEB_00152 3.6e-45 yaaA S S4 domain protein YaaA
EFMJKMEB_00153 1.5e-233 ymfF S Peptidase M16
EFMJKMEB_00154 7.4e-228 ymfH S Peptidase M16
EFMJKMEB_00155 7e-137 ymfM S sequence-specific DNA binding
EFMJKMEB_00156 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EFMJKMEB_00157 1.8e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFMJKMEB_00158 3.8e-151 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFMJKMEB_00159 1e-134 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFMJKMEB_00160 3.9e-80 lytE M LysM domain protein
EFMJKMEB_00161 8.2e-44 isaA GH23 M Immunodominant staphylococcal antigen A
EFMJKMEB_00162 6.8e-301 S Bacterial membrane protein, YfhO
EFMJKMEB_00163 2.4e-214 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EFMJKMEB_00164 2e-74 F NUDIX domain
EFMJKMEB_00165 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EFMJKMEB_00166 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EFMJKMEB_00167 8.5e-73 rplI J binds to the 23S rRNA
EFMJKMEB_00168 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EFMJKMEB_00169 8.2e-48 veg S Biofilm formation stimulator VEG
EFMJKMEB_00170 4.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EFMJKMEB_00171 2e-07
EFMJKMEB_00172 5.5e-11 ypaA M Membrane
EFMJKMEB_00173 2.1e-94 XK27_06935 K transcriptional regulator
EFMJKMEB_00174 4e-158 XK27_06930 V domain protein
EFMJKMEB_00175 3.1e-108 S Putative adhesin
EFMJKMEB_00176 9.1e-13 XK27_06920 S Protein of unknown function (DUF1700)
EFMJKMEB_00177 9.6e-08 XK27_06920 S Protein of unknown function (DUF1700)
EFMJKMEB_00178 3e-48 K transcriptional regulator, PadR family
EFMJKMEB_00179 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EFMJKMEB_00180 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EFMJKMEB_00181 5.9e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EFMJKMEB_00182 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EFMJKMEB_00183 2.8e-18 M LysM domain
EFMJKMEB_00184 1.2e-88 ebsA S Family of unknown function (DUF5322)
EFMJKMEB_00185 1.8e-139 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EFMJKMEB_00186 2.4e-43 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EFMJKMEB_00187 6e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EFMJKMEB_00188 5.4e-223 G COG0457 FOG TPR repeat
EFMJKMEB_00189 8.1e-176 yubA S permease
EFMJKMEB_00190 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
EFMJKMEB_00191 5.2e-162 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EFMJKMEB_00192 5.5e-124 ftsE D cell division ATP-binding protein FtsE
EFMJKMEB_00193 5.3e-181 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EFMJKMEB_00194 7.9e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EFMJKMEB_00195 1.3e-181 yjjH S Calcineurin-like phosphoesterase
EFMJKMEB_00196 3.3e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EFMJKMEB_00197 0.0 pacL 3.6.3.8 P cation transport ATPase
EFMJKMEB_00198 3.4e-67 ywiB S Domain of unknown function (DUF1934)
EFMJKMEB_00199 2.4e-44 XK27_00115 2.3.1.128 K acetyltransferase
EFMJKMEB_00200 9.2e-147 yidA S hydrolases of the HAD superfamily
EFMJKMEB_00201 3.4e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
EFMJKMEB_00202 4.2e-34 F Protein of unknown function (DUF454)
EFMJKMEB_00203 3.9e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
EFMJKMEB_00204 5.8e-247 vicK 2.7.13.3 T Histidine kinase
EFMJKMEB_00205 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFMJKMEB_00206 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
EFMJKMEB_00207 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EFMJKMEB_00208 1.8e-114 gltJ P ABC transporter (Permease
EFMJKMEB_00209 1.2e-109 tcyB_2 P ABC transporter (permease)
EFMJKMEB_00210 1.4e-145 endA F DNA RNA non-specific endonuclease
EFMJKMEB_00211 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
EFMJKMEB_00212 9.4e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFMJKMEB_00214 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EFMJKMEB_00215 1.3e-36 5.1.3.2 GM Psort location CytoplasmicMembrane, score
EFMJKMEB_00216 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EFMJKMEB_00217 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EFMJKMEB_00218 7.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFMJKMEB_00219 2.7e-88 ytsP 1.8.4.14 T GAF domain-containing protein
EFMJKMEB_00220 3e-162 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EFMJKMEB_00221 7.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
EFMJKMEB_00223 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EFMJKMEB_00224 2.1e-219 XK27_05110 P chloride
EFMJKMEB_00225 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
EFMJKMEB_00226 9.8e-283 clcA P Chloride transporter, ClC family
EFMJKMEB_00227 1e-75 fld C Flavodoxin
EFMJKMEB_00228 3.3e-14 XK27_08880
EFMJKMEB_00229 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
EFMJKMEB_00230 1.1e-149 estA CE1 S Putative esterase
EFMJKMEB_00231 4.3e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EFMJKMEB_00232 8.4e-134 XK27_08845 S abc transporter atp-binding protein
EFMJKMEB_00233 1.3e-143 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
EFMJKMEB_00234 5.8e-175 XK27_08835 S ABC transporter substrate binding protein
EFMJKMEB_00235 3.2e-17 S Domain of unknown function (DUF4649)
EFMJKMEB_00236 9e-11 Q the current gene model (or a revised gene model) may contain a frame shift
EFMJKMEB_00237 9.4e-14 Q the current gene model (or a revised gene model) may contain a frame shift
EFMJKMEB_00239 8.3e-10 Q the current gene model (or a revised gene model) may contain a frame shift
EFMJKMEB_00240 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
EFMJKMEB_00241 1.9e-200 ylbM S Belongs to the UPF0348 family
EFMJKMEB_00242 1.3e-139 yqeM Q Methyltransferase domain protein
EFMJKMEB_00243 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EFMJKMEB_00244 4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EFMJKMEB_00245 1.7e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EFMJKMEB_00246 3.5e-49 yhbY J RNA-binding protein
EFMJKMEB_00247 7.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EFMJKMEB_00248 1.8e-98 yqeG S hydrolase of the HAD superfamily
EFMJKMEB_00249 2.1e-62 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EFMJKMEB_00250 4.5e-80 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EFMJKMEB_00251 1.6e-64
EFMJKMEB_00252 5.1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFMJKMEB_00253 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EFMJKMEB_00254 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFMJKMEB_00255 7.3e-258 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFMJKMEB_00256 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EFMJKMEB_00257 4.8e-154 hlpA M Belongs to the NlpA lipoprotein family
EFMJKMEB_00258 7.5e-100 pncA Q isochorismatase
EFMJKMEB_00259 2.8e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EFMJKMEB_00260 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
EFMJKMEB_00261 6.9e-75 XK27_03180 T universal stress protein
EFMJKMEB_00263 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EFMJKMEB_00264 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
EFMJKMEB_00265 2.1e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
EFMJKMEB_00266 0.0 yjcE P NhaP-type Na H and K H antiporters
EFMJKMEB_00268 2e-97 ytqB 2.1.1.176 J (SAM)-dependent
EFMJKMEB_00269 1.3e-179 yhcC S radical SAM protein
EFMJKMEB_00270 7.8e-194 ylbL T Belongs to the peptidase S16 family
EFMJKMEB_00271 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EFMJKMEB_00272 4.3e-92 rsmD 2.1.1.171 L Methyltransferase
EFMJKMEB_00273 5.5e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EFMJKMEB_00274 1.1e-09 S Protein of unknown function (DUF4059)
EFMJKMEB_00275 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
EFMJKMEB_00276 2.3e-162 yxeN P ABC transporter (Permease
EFMJKMEB_00277 4.8e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EFMJKMEB_00279 8.8e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFMJKMEB_00280 0.0 pflB 2.3.1.54 C formate acetyltransferase'
EFMJKMEB_00281 7.2e-43 cah 4.2.1.1 P carbonic anhydrase
EFMJKMEB_00282 2.9e-38 cah 4.2.1.1 P carbonic anhydrase
EFMJKMEB_00283 1e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFMJKMEB_00285 1.5e-86 L Plasmid recombination enzyme
EFMJKMEB_00286 1.2e-32 L DNA integration
EFMJKMEB_00287 4.8e-58 L Phage integrase family
EFMJKMEB_00288 7.6e-118 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
EFMJKMEB_00289 2.3e-123 ybbM S transport system, permease component
EFMJKMEB_00290 6.8e-116 ybbL S abc transporter atp-binding protein
EFMJKMEB_00291 3.1e-31
EFMJKMEB_00292 1.5e-183 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
EFMJKMEB_00293 2.8e-137 cppA E CppA N-terminal
EFMJKMEB_00294 3.2e-89 L Transposase
EFMJKMEB_00295 1.4e-135 HJ the current gene model (or a revised gene model) may contain a frame shift
EFMJKMEB_00296 6.7e-125 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFMJKMEB_00297 1e-09 K CsbD-like
EFMJKMEB_00298 9e-77 M Protein conserved in bacteria
EFMJKMEB_00299 9.7e-22 S Small integral membrane protein
EFMJKMEB_00300 4.5e-39
EFMJKMEB_00301 3.3e-31
EFMJKMEB_00302 3.7e-27 S Membrane
EFMJKMEB_00303 5.4e-197 L transposase, IS4 family
EFMJKMEB_00304 2e-83 norB P Major facilitator superfamily
EFMJKMEB_00305 4.3e-33 L Transposase
EFMJKMEB_00306 1.1e-99 fic D Fic/DOC family
EFMJKMEB_00307 6.5e-27
EFMJKMEB_00308 2.1e-60
EFMJKMEB_00309 0.0 ctpE P E1-E2 ATPase
EFMJKMEB_00310 1.1e-35
EFMJKMEB_00311 1.5e-35 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
EFMJKMEB_00312 4.6e-252 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EFMJKMEB_00313 2e-103 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
EFMJKMEB_00314 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EFMJKMEB_00315 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EFMJKMEB_00316 1.1e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
EFMJKMEB_00317 3.8e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EFMJKMEB_00318 6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EFMJKMEB_00319 2.7e-73 copY K Copper transport repressor, CopY TcrY family
EFMJKMEB_00320 0.0 copA 3.6.3.54 P P-type ATPase
EFMJKMEB_00321 3e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
EFMJKMEB_00322 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EFMJKMEB_00323 8.6e-114 papP P ABC transporter (Permease
EFMJKMEB_00324 3e-106 P ABC transporter (Permease
EFMJKMEB_00325 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
EFMJKMEB_00326 1.1e-155 cjaA ET ABC transporter substrate-binding protein
EFMJKMEB_00329 5.7e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EFMJKMEB_00330 7.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
EFMJKMEB_00331 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EFMJKMEB_00332 1.4e-84 yjbB G Permeases of the major facilitator superfamily
EFMJKMEB_00333 3.1e-64 yjbB G Permeases of the major facilitator superfamily
EFMJKMEB_00334 1.4e-153 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EFMJKMEB_00335 5.6e-98 thiT S Thiamine transporter
EFMJKMEB_00336 2.5e-62 yjqA S Bacterial PH domain
EFMJKMEB_00337 7.4e-145 corA P CorA-like protein
EFMJKMEB_00338 1.1e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EFMJKMEB_00339 1e-41 yazA L endonuclease containing a URI domain
EFMJKMEB_00340 3.9e-139 yabB 2.1.1.223 L Methyltransferase
EFMJKMEB_00341 1.8e-140 nodB3 G deacetylase
EFMJKMEB_00342 1.7e-142 plsC 2.3.1.51 I Acyltransferase
EFMJKMEB_00343 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EFMJKMEB_00344 0.0 comEC S Competence protein ComEC
EFMJKMEB_00345 1.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFMJKMEB_00346 7.3e-85 nylA 3.5.1.4 J Belongs to the amidase family
EFMJKMEB_00347 8.5e-79 yckB ET Belongs to the bacterial solute-binding protein 3 family
EFMJKMEB_00348 1.1e-47 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
EFMJKMEB_00349 4.1e-66 yecS P ABC transporter (Permease
EFMJKMEB_00350 3.5e-21 yecS P amino acid transport
EFMJKMEB_00352 2.6e-23 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
EFMJKMEB_00353 1.4e-87 yfiF3 K sequence-specific DNA binding
EFMJKMEB_00354 1.6e-23 bglC K Transcriptional regulator
EFMJKMEB_00355 8.6e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EFMJKMEB_00356 7.6e-239 agcS E (Alanine) symporter
EFMJKMEB_00357 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EFMJKMEB_00358 2.3e-240 metY 2.5.1.49 E o-acetylhomoserine
EFMJKMEB_00359 3.2e-133 S haloacid dehalogenase-like hydrolase
EFMJKMEB_00360 3.8e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EFMJKMEB_00361 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
EFMJKMEB_00362 3.1e-31 M1-755 P Hemerythrin HHE cation binding domain protein
EFMJKMEB_00363 5.8e-78 XK27_04775 S hemerythrin HHE cation binding domain
EFMJKMEB_00364 4e-32 XK27_04775 S hemerythrin HHE cation binding domain
EFMJKMEB_00365 1.3e-28 XK27_04775 S hemerythrin HHE cation binding domain
EFMJKMEB_00366 1.1e-34 XK27_04775 S hemerythrin HHE cation binding domain
EFMJKMEB_00367 8.4e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EFMJKMEB_00368 5.5e-172 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EFMJKMEB_00369 3e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EFMJKMEB_00370 6.7e-44 yktA S Belongs to the UPF0223 family
EFMJKMEB_00371 4.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EFMJKMEB_00372 3.9e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EFMJKMEB_00373 4.8e-157 pstS P phosphate
EFMJKMEB_00374 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
EFMJKMEB_00375 1.5e-155 pstA P phosphate transport system permease
EFMJKMEB_00376 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EFMJKMEB_00377 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EFMJKMEB_00378 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
EFMJKMEB_00379 0.0 pepN 3.4.11.2 E aminopeptidase
EFMJKMEB_00380 1e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
EFMJKMEB_00381 1.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
EFMJKMEB_00384 3.7e-09
EFMJKMEB_00385 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EFMJKMEB_00386 1.7e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
EFMJKMEB_00387 5.9e-49 malR K Transcriptional regulator
EFMJKMEB_00388 2.3e-23 L Transposase
EFMJKMEB_00389 4.6e-25 tatA U protein secretion
EFMJKMEB_00390 4.4e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EFMJKMEB_00391 7.2e-303 ywbL P COG0672 High-affinity Fe2 Pb2 permease
EFMJKMEB_00392 5.6e-233 ycdB P peroxidase
EFMJKMEB_00393 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
EFMJKMEB_00394 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFMJKMEB_00395 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFMJKMEB_00396 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFMJKMEB_00397 2.9e-208 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFMJKMEB_00398 7e-173 3.5.1.28 M GBS Bsp-like repeat
EFMJKMEB_00399 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EFMJKMEB_00400 9.9e-12 3.5.1.28 NU amidase activity
EFMJKMEB_00401 1.4e-292 lpdA 1.8.1.4 C Dehydrogenase
EFMJKMEB_00402 3.2e-89 L Transposase
EFMJKMEB_00403 4.8e-59 XK27_01265 S ECF-type riboflavin transporter, S component
EFMJKMEB_00404 3.6e-293 yfmM S abc transporter atp-binding protein
EFMJKMEB_00405 8.3e-257 noxE P NADH oxidase
EFMJKMEB_00406 1.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EFMJKMEB_00407 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFMJKMEB_00408 1.6e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
EFMJKMEB_00409 9.8e-52 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
EFMJKMEB_00410 5.3e-165 ypuA S secreted protein
EFMJKMEB_00411 8.8e-60 L Transposase (IS116 IS110 IS902 family)
EFMJKMEB_00412 4.2e-71 L Transposase (IS116 IS110 IS902 family)
EFMJKMEB_00414 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFMJKMEB_00415 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFMJKMEB_00416 8.5e-34 nrdH O Glutaredoxin
EFMJKMEB_00417 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EFMJKMEB_00418 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
EFMJKMEB_00419 8.2e-221 icd 1.1.1.42 C Isocitrate dehydrogenase
EFMJKMEB_00420 7.9e-39 ptsH G phosphocarrier protein Hpr
EFMJKMEB_00421 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EFMJKMEB_00422 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
EFMJKMEB_00423 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EFMJKMEB_00424 1.9e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
EFMJKMEB_00425 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
EFMJKMEB_00426 0.0 uup S abc transporter atp-binding protein
EFMJKMEB_00428 3.1e-130 pip 1.11.1.10 S Alpha beta hydrolase
EFMJKMEB_00429 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EFMJKMEB_00430 8.7e-150 cobQ S glutamine amidotransferase
EFMJKMEB_00431 7e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
EFMJKMEB_00432 2.8e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EFMJKMEB_00433 4.3e-167 ybbR S Protein conserved in bacteria
EFMJKMEB_00434 8.2e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EFMJKMEB_00435 1.3e-70 gtrA S GtrA-like protein
EFMJKMEB_00436 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
EFMJKMEB_00437 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EFMJKMEB_00438 7e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
EFMJKMEB_00439 2.3e-100 zupT P Mediates zinc uptake. May also transport other divalent cations
EFMJKMEB_00440 4.5e-205 yurR 1.4.5.1 E oxidoreductase
EFMJKMEB_00441 5.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EFMJKMEB_00442 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EFMJKMEB_00443 9.6e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EFMJKMEB_00446 3.2e-89 L Transposase
EFMJKMEB_00447 1.6e-84 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EFMJKMEB_00448 2.6e-47 yhaI L Membrane
EFMJKMEB_00449 1e-55 S Domain of unknown function (DUF4173)
EFMJKMEB_00450 1.2e-94 ureI S AmiS/UreI family transporter
EFMJKMEB_00451 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EFMJKMEB_00452 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EFMJKMEB_00453 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EFMJKMEB_00454 6.6e-78 ureE O enzyme active site formation
EFMJKMEB_00455 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EFMJKMEB_00456 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EFMJKMEB_00457 3.7e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EFMJKMEB_00458 2.7e-177 cbiM P PDGLE domain
EFMJKMEB_00459 3.7e-137 P cobalt transport protein
EFMJKMEB_00460 1.6e-131 cbiO P ABC transporter
EFMJKMEB_00461 5.3e-153 ET amino acid transport
EFMJKMEB_00462 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFMJKMEB_00463 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
EFMJKMEB_00464 3.8e-205 EGP Transmembrane secretion effector
EFMJKMEB_00465 4.5e-144 ET amino acid transport
EFMJKMEB_00466 5.8e-158 metQ M Belongs to the NlpA lipoprotein family
EFMJKMEB_00467 1.8e-256 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
EFMJKMEB_00468 5.2e-182 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EFMJKMEB_00469 2e-97 metI P ABC transporter (Permease
EFMJKMEB_00470 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EFMJKMEB_00471 4.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
EFMJKMEB_00472 8e-94 S UPF0397 protein
EFMJKMEB_00473 0.0 ykoD P abc transporter atp-binding protein
EFMJKMEB_00474 1.6e-149 cbiQ P cobalt transport
EFMJKMEB_00475 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EFMJKMEB_00476 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
EFMJKMEB_00477 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
EFMJKMEB_00478 3.4e-242 P COG0168 Trk-type K transport systems, membrane components
EFMJKMEB_00479 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
EFMJKMEB_00480 9e-90 yceD K metal-binding, possibly nucleic acid-binding protein
EFMJKMEB_00481 3.3e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFMJKMEB_00482 3e-276 T PhoQ Sensor
EFMJKMEB_00483 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EFMJKMEB_00484 1.9e-217 dnaB L Replication initiation and membrane attachment
EFMJKMEB_00485 8.9e-167 dnaI L Primosomal protein DnaI
EFMJKMEB_00486 1.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EFMJKMEB_00487 4.2e-13 yrdC 3.5.1.19 Q isochorismatase
EFMJKMEB_00488 1.4e-27 yrdC 3.5.1.19 Q isochorismatase
EFMJKMEB_00489 3.7e-232 amt P Ammonium Transporter
EFMJKMEB_00490 1.2e-52 glnB K Belongs to the P(II) protein family
EFMJKMEB_00491 1.3e-103 mur1 NU mannosyl-glycoprotein
EFMJKMEB_00492 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
EFMJKMEB_00493 1.2e-92 nptA P COG1283 Na phosphate symporter
EFMJKMEB_00494 8e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EFMJKMEB_00495 2.5e-50
EFMJKMEB_00496 2.2e-25
EFMJKMEB_00497 8.7e-60
EFMJKMEB_00498 5.2e-62 S membrane
EFMJKMEB_00499 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EFMJKMEB_00500 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EFMJKMEB_00501 4.5e-39 ynzC S UPF0291 protein
EFMJKMEB_00502 2.6e-250 cycA E permease
EFMJKMEB_00503 1.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
EFMJKMEB_00504 7.4e-25 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EFMJKMEB_00505 6.8e-119 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
EFMJKMEB_00506 1.3e-53 pts33BCA G pts system
EFMJKMEB_00507 4.1e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EFMJKMEB_00512 1.5e-166 fhuR K transcriptional regulator (lysR family)
EFMJKMEB_00513 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EFMJKMEB_00514 8.5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EFMJKMEB_00515 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EFMJKMEB_00516 1.9e-226 pyrP F uracil Permease
EFMJKMEB_00517 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EFMJKMEB_00518 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
EFMJKMEB_00519 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
EFMJKMEB_00520 2.5e-122 2.1.1.223 S Putative SAM-dependent methyltransferase
EFMJKMEB_00521 4.2e-175 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EFMJKMEB_00522 3.7e-120 macB V ABC transporter, ATP-binding protein
EFMJKMEB_00523 7.1e-212 V permease protein
EFMJKMEB_00524 0.0 L SNF2 family N-terminal domain
EFMJKMEB_00525 1.4e-71 S Domain of unknown function (DUF4391)
EFMJKMEB_00527 0.0 res 3.1.21.5 L restriction endonuclease
EFMJKMEB_00528 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EFMJKMEB_00529 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EFMJKMEB_00530 7.9e-64 L Transposase
EFMJKMEB_00531 3.2e-98 L Transposase
EFMJKMEB_00532 1.6e-18 L Integrase core domain
EFMJKMEB_00533 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
EFMJKMEB_00534 2.8e-164 hrtB V MacB-like periplasmic core domain
EFMJKMEB_00537 3e-92 S MucBP domain
EFMJKMEB_00538 1.9e-49 M YSIRK type signal peptide
EFMJKMEB_00539 0.0 M the current gene model (or a revised gene model) may contain a
EFMJKMEB_00541 0.0 mdlB V abc transporter atp-binding protein
EFMJKMEB_00542 0.0 lmrA V abc transporter atp-binding protein
EFMJKMEB_00543 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EFMJKMEB_00544 2.9e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EFMJKMEB_00545 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
EFMJKMEB_00546 2.1e-131 rr02 KT response regulator
EFMJKMEB_00547 9.7e-83 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EFMJKMEB_00548 1.7e-107 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EFMJKMEB_00549 4.8e-168 V ABC transporter
EFMJKMEB_00550 5.4e-122 sagI S ABC-2 type transporter
EFMJKMEB_00551 6.5e-195 yceA S Belongs to the UPF0176 family
EFMJKMEB_00552 1.6e-28 XK27_00085 K Transcriptional
EFMJKMEB_00553 7.4e-22
EFMJKMEB_00554 2.8e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
EFMJKMEB_00555 5.6e-113 S VIT family
EFMJKMEB_00556 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EFMJKMEB_00557 1.5e-219 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EFMJKMEB_00558 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
EFMJKMEB_00559 3.8e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EFMJKMEB_00560 2.2e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EFMJKMEB_00561 8.8e-104 GBS0088 J protein conserved in bacteria
EFMJKMEB_00562 1.6e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EFMJKMEB_00563 1.1e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EFMJKMEB_00564 3.1e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
EFMJKMEB_00565 6.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EFMJKMEB_00566 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EFMJKMEB_00567 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
EFMJKMEB_00568 2.5e-21
EFMJKMEB_00569 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EFMJKMEB_00571 3e-29 U protein secretion
EFMJKMEB_00572 1.8e-49 U protein secretion
EFMJKMEB_00573 2.5e-08 M Pilin isopeptide linkage domain protein
EFMJKMEB_00574 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
EFMJKMEB_00575 3.4e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EFMJKMEB_00576 3.5e-49 XK27_13030
EFMJKMEB_00577 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EFMJKMEB_00578 2.2e-168 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EFMJKMEB_00579 9.8e-163 S Protein of unknown function (DUF3114)
EFMJKMEB_00580 1.2e-22 S Protein of unknown function (DUF3114)
EFMJKMEB_00581 4.7e-120 yqfA K protein, Hemolysin III
EFMJKMEB_00582 1.6e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EFMJKMEB_00583 2.9e-218 mvaS 2.3.3.10 I synthase
EFMJKMEB_00584 1.9e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EFMJKMEB_00585 5.3e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EFMJKMEB_00586 9.7e-22
EFMJKMEB_00587 3.7e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EFMJKMEB_00588 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
EFMJKMEB_00589 1.3e-249 mmuP E amino acid
EFMJKMEB_00590 3.1e-178 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
EFMJKMEB_00591 1.4e-29 S Domain of unknown function (DUF1912)
EFMJKMEB_00592 8.3e-15 L Helix-hairpin-helix DNA-binding motif class 1
EFMJKMEB_00593 1.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EFMJKMEB_00594 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EFMJKMEB_00595 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EFMJKMEB_00596 3.4e-199 ilvE 2.6.1.42 E Aminotransferase
EFMJKMEB_00597 1.1e-15 S Protein of unknown function (DUF2969)
EFMJKMEB_00600 1.3e-202 rpsA 1.17.7.4 J ribosomal protein S1
EFMJKMEB_00603 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
EFMJKMEB_00604 6.1e-70 M Pfam SNARE associated Golgi protein
EFMJKMEB_00605 9.8e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
EFMJKMEB_00606 3e-51 S oxidoreductase
EFMJKMEB_00607 1.4e-54 S oxidoreductase
EFMJKMEB_00608 2.4e-47 XK27_09445 S Domain of unknown function (DUF1827)
EFMJKMEB_00609 5.7e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EFMJKMEB_00610 0.0 clpE O Belongs to the ClpA ClpB family
EFMJKMEB_00611 3.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EFMJKMEB_00612 1.3e-34 ykuJ S protein conserved in bacteria
EFMJKMEB_00613 3.2e-116 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
EFMJKMEB_00614 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
EFMJKMEB_00615 1.2e-77 feoA P FeoA domain protein
EFMJKMEB_00616 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EFMJKMEB_00617 1.5e-07
EFMJKMEB_00618 1.9e-33 yugF I carboxylic ester hydrolase activity
EFMJKMEB_00619 1.5e-23 I Alpha/beta hydrolase family
EFMJKMEB_00620 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EFMJKMEB_00621 1.7e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EFMJKMEB_00622 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
EFMJKMEB_00623 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EFMJKMEB_00625 3.6e-77 licT K antiterminator
EFMJKMEB_00626 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EFMJKMEB_00627 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EFMJKMEB_00628 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EFMJKMEB_00629 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EFMJKMEB_00630 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EFMJKMEB_00631 1.6e-219 mdtG EGP Major facilitator Superfamily
EFMJKMEB_00632 2.6e-33 secG U Preprotein translocase subunit SecG
EFMJKMEB_00633 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EFMJKMEB_00634 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EFMJKMEB_00635 1.1e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EFMJKMEB_00636 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
EFMJKMEB_00637 2.7e-210 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
EFMJKMEB_00638 3.7e-182 ccpA K Catabolite control protein A
EFMJKMEB_00639 5.2e-27 yyaQ S YjbR
EFMJKMEB_00640 2.9e-111 yyaQ S YjbR
EFMJKMEB_00641 2.9e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EFMJKMEB_00642 5.7e-77 yueI S Protein of unknown function (DUF1694)
EFMJKMEB_00643 8.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EFMJKMEB_00644 1.3e-24 WQ51_00785
EFMJKMEB_00645 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EFMJKMEB_00646 2.6e-219 ywbD 2.1.1.191 J Methyltransferase
EFMJKMEB_00647 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EFMJKMEB_00648 1.5e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EFMJKMEB_00649 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EFMJKMEB_00650 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EFMJKMEB_00651 6.3e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EFMJKMEB_00652 3.2e-53 yheA S Belongs to the UPF0342 family
EFMJKMEB_00653 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EFMJKMEB_00654 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EFMJKMEB_00655 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EFMJKMEB_00656 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
EFMJKMEB_00657 9e-238 msrR K Transcriptional regulator
EFMJKMEB_00658 4.3e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
EFMJKMEB_00659 7e-203 I acyl-CoA dehydrogenase
EFMJKMEB_00660 4.5e-97 mip S hydroperoxide reductase activity
EFMJKMEB_00661 1.8e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFMJKMEB_00662 1.1e-20
EFMJKMEB_00663 1.9e-139 repA S Replication initiator protein A (RepA) N-terminus
EFMJKMEB_00664 7.4e-258 hpaIIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
EFMJKMEB_00665 6.5e-75 XK27_00590
EFMJKMEB_00666 1.2e-64 XK27_00585 P arsenate reductase (glutaredoxin) activity
EFMJKMEB_00667 1.5e-36 XK27_00580
EFMJKMEB_00668 8.3e-89 ypbD S CAAX protease self-immunity
EFMJKMEB_00669 9.3e-78 XK27_00570
EFMJKMEB_00670 0.0 traG U Type IV secretory system Conjugative DNA transfer
EFMJKMEB_00671 4.6e-33 XK27_00560
EFMJKMEB_00672 9.7e-139
EFMJKMEB_00673 7.5e-61 XK27_00550 S PrgI family protein
EFMJKMEB_00674 0.0 U 'COG3451 Type IV secretory pathway, VirB4 components'
EFMJKMEB_00675 0.0 XK27_00530 S CHAP domain
EFMJKMEB_00676 4.4e-48 V Abi-like protein
EFMJKMEB_00677 1.1e-94 V Abi-like protein
EFMJKMEB_00678 0.0 XK27_00515 D Glucan-binding protein C
EFMJKMEB_00679 5.1e-11 XK27_00510
EFMJKMEB_00680 1.6e-89 XK27_00505
EFMJKMEB_00681 0.0 XK27_00500 L SNF2 family N-terminal domain
EFMJKMEB_00682 6e-43
EFMJKMEB_00683 2.4e-36
EFMJKMEB_00684 7.1e-102 XK27_10865
EFMJKMEB_00685 3.8e-188 L Toprim-like
EFMJKMEB_00686 2.5e-17 XK27_10875
EFMJKMEB_00687 1.5e-57 XK27_10880
EFMJKMEB_00688 1.5e-30
EFMJKMEB_00689 1.6e-82 nprA K Cro/C1-type HTH DNA-binding domain
EFMJKMEB_00690 2.3e-131 2.7.1.176 O Zeta toxin
EFMJKMEB_00691 0.0 L ATP-dependent endonuclease of the OLD family
EFMJKMEB_00692 1.3e-302 L Superfamily I DNA and RNA helicases
EFMJKMEB_00693 1.1e-220 K Putative DNA-binding domain
EFMJKMEB_00694 1.5e-56
EFMJKMEB_00695 1.1e-57 S Bacterial mobilisation protein (MobC)
EFMJKMEB_00696 0.0 U relaxase
EFMJKMEB_00697 9.7e-250 T PhoQ Sensor
EFMJKMEB_00698 5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFMJKMEB_00699 3.2e-89 L Transposase
EFMJKMEB_00704 3.6e-138 mreC M Involved in formation and maintenance of cell shape
EFMJKMEB_00705 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EFMJKMEB_00706 4.1e-99 usp 3.5.1.28 CBM50 S CHAP domain
EFMJKMEB_00707 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EFMJKMEB_00708 2.5e-26
EFMJKMEB_00709 8.5e-218 araT 2.6.1.1 E Aminotransferase
EFMJKMEB_00710 1e-142 recO L Involved in DNA repair and RecF pathway recombination
EFMJKMEB_00711 5.1e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EFMJKMEB_00712 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EFMJKMEB_00713 4.4e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EFMJKMEB_00714 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFMJKMEB_00715 8.6e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EFMJKMEB_00716 3.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EFMJKMEB_00717 5.2e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EFMJKMEB_00718 1.4e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EFMJKMEB_00719 5e-57 L transposase activity
EFMJKMEB_00720 4.6e-52 L transposition
EFMJKMEB_00721 1.5e-30 L Integrase core domain protein
EFMJKMEB_00722 7.5e-160 S CHAP domain
EFMJKMEB_00723 2e-241 purD 6.3.4.13 F Belongs to the GARS family
EFMJKMEB_00724 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EFMJKMEB_00725 1.9e-203 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EFMJKMEB_00726 9.3e-46 1.1.1.169 H Ketopantoate reductase
EFMJKMEB_00727 5.6e-86 1.1.1.169 H Ketopantoate reductase
EFMJKMEB_00728 6.6e-34
EFMJKMEB_00729 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EFMJKMEB_00730 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EFMJKMEB_00731 8.2e-70 argR K Regulates arginine biosynthesis genes
EFMJKMEB_00732 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EFMJKMEB_00733 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EFMJKMEB_00734 2.3e-78 S Protein of unknown function (DUF3021)
EFMJKMEB_00735 5.4e-69 K LytTr DNA-binding domain
EFMJKMEB_00737 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EFMJKMEB_00739 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EFMJKMEB_00740 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
EFMJKMEB_00741 2.9e-232 cinA 3.5.1.42 S Belongs to the CinA family
EFMJKMEB_00742 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EFMJKMEB_00743 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
EFMJKMEB_00744 2.4e-90 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EFMJKMEB_00745 4.9e-122 comFC S Competence protein
EFMJKMEB_00746 2e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EFMJKMEB_00747 6.3e-111 yvyE 3.4.13.9 S YigZ family
EFMJKMEB_00748 4.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EFMJKMEB_00749 9.3e-42 acuB S IMP dehydrogenase activity
EFMJKMEB_00750 1e-39 acuB S CBS domain
EFMJKMEB_00751 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
EFMJKMEB_00752 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
EFMJKMEB_00753 3.2e-138 livM E Belongs to the binding-protein-dependent transport system permease family
EFMJKMEB_00754 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
EFMJKMEB_00755 9.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
EFMJKMEB_00756 7.1e-46 ylbG S UPF0298 protein
EFMJKMEB_00757 1.3e-73 ylbF S Belongs to the UPF0342 family
EFMJKMEB_00758 8.3e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EFMJKMEB_00759 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EFMJKMEB_00760 8e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
EFMJKMEB_00761 2.8e-221 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EFMJKMEB_00762 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
EFMJKMEB_00763 2.3e-91 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
EFMJKMEB_00764 1e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
EFMJKMEB_00765 7.9e-274 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EFMJKMEB_00766 5.9e-225 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
EFMJKMEB_00768 3.8e-73 yvdD 3.2.2.10 S Belongs to the LOG family
EFMJKMEB_00769 6.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EFMJKMEB_00770 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EFMJKMEB_00771 1.4e-41 ylxQ J ribosomal protein
EFMJKMEB_00772 3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
EFMJKMEB_00773 3.1e-212 nusA K Participates in both transcription termination and antitermination
EFMJKMEB_00774 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
EFMJKMEB_00775 5.7e-217 brpA K Transcriptional
EFMJKMEB_00776 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
EFMJKMEB_00777 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
EFMJKMEB_00778 3e-241 pbuO S permease
EFMJKMEB_00779 5.6e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
EFMJKMEB_00780 4.9e-139 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
EFMJKMEB_00781 3.1e-173 manL 2.7.1.191 G pts system
EFMJKMEB_00782 3.9e-116 manM G pts system
EFMJKMEB_00783 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
EFMJKMEB_00784 4.2e-62 manO S protein conserved in bacteria
EFMJKMEB_00785 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EFMJKMEB_00788 3.9e-17 L Psort location Cytoplasmic, score
EFMJKMEB_00789 5.6e-129 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EFMJKMEB_00790 3.9e-59 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EFMJKMEB_00791 7.1e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EFMJKMEB_00792 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EFMJKMEB_00793 2.2e-142 S SseB protein N-terminal domain
EFMJKMEB_00794 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
EFMJKMEB_00795 1.5e-255 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EFMJKMEB_00796 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EFMJKMEB_00799 2.4e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFMJKMEB_00800 4.6e-91 yacP S RNA-binding protein containing a PIN domain
EFMJKMEB_00801 2.8e-154 degV S DegV family
EFMJKMEB_00802 4.3e-20 K helix-turn-helix
EFMJKMEB_00803 3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFMJKMEB_00804 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EFMJKMEB_00805 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
EFMJKMEB_00806 6.7e-210 L Phage integrase family
EFMJKMEB_00807 1e-33 S Helix-turn-helix domain
EFMJKMEB_00808 8.4e-97 S Plasmid replication protein
EFMJKMEB_00809 2.3e-65
EFMJKMEB_00810 1.2e-197 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EFMJKMEB_00811 1.9e-47
EFMJKMEB_00813 4.3e-181 norB P Major Facilitator Superfamily
EFMJKMEB_00814 3.8e-78 C nadph quinone reductase
EFMJKMEB_00815 1.4e-37 K Transcriptional regulator
EFMJKMEB_00816 1.4e-68 S phosphonoacetaldehyde hydrolase activity
EFMJKMEB_00817 1.7e-28 pcaC 3.1.1.24, 4.1.1.44 S peroxiredoxin activity
EFMJKMEB_00818 6.5e-31 ais G Phosphoglycerate mutase
EFMJKMEB_00821 3.6e-128 tnp L Transposase IS66 family
EFMJKMEB_00822 2.8e-224 capA M Bacterial capsule synthesis protein
EFMJKMEB_00823 6.1e-39 gcvR T UPF0237 protein
EFMJKMEB_00824 3.9e-243 XK27_08635 S UPF0210 protein
EFMJKMEB_00825 2.4e-135 ais G Phosphoglycerate mutase
EFMJKMEB_00826 7.9e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EFMJKMEB_00827 7.2e-101 acmA 3.2.1.17 NU amidase activity
EFMJKMEB_00828 5.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EFMJKMEB_00829 1.9e-69 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EFMJKMEB_00830 8.4e-281 dnaK O Heat shock 70 kDa protein
EFMJKMEB_00831 2.8e-181 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EFMJKMEB_00832 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EFMJKMEB_00833 1.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
EFMJKMEB_00834 3.3e-72 hmpT S cog cog4720
EFMJKMEB_00835 9.1e-87 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EFMJKMEB_00836 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EFMJKMEB_00837 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
EFMJKMEB_00838 6.4e-29 2.3.1.128 K acetyltransferase
EFMJKMEB_00839 4.9e-39 2.3.1.128 K acetyltransferase
EFMJKMEB_00840 3e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EFMJKMEB_00841 4.2e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EFMJKMEB_00842 1.8e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EFMJKMEB_00843 5.7e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
EFMJKMEB_00845 1.7e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EFMJKMEB_00846 3e-259 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EFMJKMEB_00847 0.0 fruA 2.7.1.202 G phosphotransferase system
EFMJKMEB_00848 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EFMJKMEB_00849 1.2e-121 fruR K transcriptional
EFMJKMEB_00850 1.8e-84 L Transposase
EFMJKMEB_00851 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
EFMJKMEB_00852 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EFMJKMEB_00853 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EFMJKMEB_00854 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EFMJKMEB_00855 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EFMJKMEB_00856 4.3e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EFMJKMEB_00857 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EFMJKMEB_00858 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EFMJKMEB_00859 1.6e-126 IQ reductase
EFMJKMEB_00860 1.9e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EFMJKMEB_00861 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
EFMJKMEB_00862 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EFMJKMEB_00863 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EFMJKMEB_00864 4e-72 marR K Transcriptional regulator, MarR family
EFMJKMEB_00865 4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
EFMJKMEB_00866 1.6e-114 S Haloacid dehalogenase-like hydrolase
EFMJKMEB_00867 2e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
EFMJKMEB_00868 6.7e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
EFMJKMEB_00869 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFMJKMEB_00870 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
EFMJKMEB_00871 7.8e-102 ygaC J Belongs to the UPF0374 family
EFMJKMEB_00872 4.1e-107 S Domain of unknown function (DUF1803)
EFMJKMEB_00873 1.3e-105 tnpR L Resolvase, N terminal domain
EFMJKMEB_00875 1.6e-282 repE K Primase C terminal 1 (PriCT-1)
EFMJKMEB_00876 4.2e-22 K Helix-turn-helix XRE-family like proteins
EFMJKMEB_00877 6.7e-44 MU cell adhesion
EFMJKMEB_00878 1.4e-62
EFMJKMEB_00879 1.3e-118
EFMJKMEB_00880 6.7e-141
EFMJKMEB_00881 4.7e-155
EFMJKMEB_00882 1e-309 traK U TraM recognition site of TraD and TraG
EFMJKMEB_00883 7.8e-60
EFMJKMEB_00884 6.6e-88
EFMJKMEB_00885 1.1e-211 GH23 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EFMJKMEB_00886 7.7e-239 S WXG100 protein secretion system (Wss), protein YukC
EFMJKMEB_00887 0.0 traE U AAA-like domain
EFMJKMEB_00888 3.4e-112
EFMJKMEB_00889 3.7e-53
EFMJKMEB_00890 9.3e-53 S Cag pathogenicity island, type IV secretory system
EFMJKMEB_00891 0.0 traA L MobA/MobL family
EFMJKMEB_00892 5.6e-25
EFMJKMEB_00893 3.6e-36
EFMJKMEB_00894 1.5e-25
EFMJKMEB_00895 2.3e-87 O DnaJ molecular chaperone homology domain
EFMJKMEB_00896 2.1e-54
EFMJKMEB_00897 1.1e-145 2.7.1.176 S Zeta toxin
EFMJKMEB_00898 2.3e-41 S Bacterial epsilon antitoxin
EFMJKMEB_00899 2.8e-31 S Omega Transcriptional Repressor
EFMJKMEB_00900 3.9e-162 D AAA domain
EFMJKMEB_00901 5.6e-133 V ATPase activity
EFMJKMEB_00902 9.8e-121 skfE V abc transporter atp-binding protein
EFMJKMEB_00903 8.6e-63 yvoA_1 K Transcriptional
EFMJKMEB_00904 2.1e-148 supH S overlaps another CDS with the same product name
EFMJKMEB_00905 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
EFMJKMEB_00906 1.3e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EFMJKMEB_00907 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EFMJKMEB_00908 1.1e-44 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
EFMJKMEB_00909 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EFMJKMEB_00910 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EFMJKMEB_00911 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EFMJKMEB_00912 3.2e-130 stp 3.1.3.16 T phosphatase
EFMJKMEB_00913 2.9e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
EFMJKMEB_00914 9.1e-119 yvqF KT membrane
EFMJKMEB_00915 3.8e-174 vraS 2.7.13.3 T Histidine kinase
EFMJKMEB_00916 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFMJKMEB_00919 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EFMJKMEB_00920 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EFMJKMEB_00921 2.5e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EFMJKMEB_00922 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EFMJKMEB_00923 3.6e-117 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFMJKMEB_00924 6.9e-57 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFMJKMEB_00925 1e-11 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFMJKMEB_00926 2.1e-82 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFMJKMEB_00927 5.9e-25 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EFMJKMEB_00928 0.0 lacL 3.2.1.23 G -beta-galactosidase
EFMJKMEB_00929 0.0 lacS G transporter
EFMJKMEB_00930 8.7e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EFMJKMEB_00931 2.1e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EFMJKMEB_00932 2.8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EFMJKMEB_00933 1.1e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EFMJKMEB_00934 1.3e-182 galR K Transcriptional regulator
EFMJKMEB_00935 1.2e-08 L Integrase core domain protein
EFMJKMEB_00936 6.7e-24 L transposition
EFMJKMEB_00937 8.1e-258 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
EFMJKMEB_00938 6.5e-102 V abc transporter atp-binding protein
EFMJKMEB_00939 2.1e-39 V (ABC) transporter
EFMJKMEB_00940 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
EFMJKMEB_00942 1.4e-273 S Protein of unknown function (DUF3114)
EFMJKMEB_00943 1.4e-50 2.3.1.128 K Acetyltransferase GNAT Family
EFMJKMEB_00944 5.6e-133 V (ABC) transporter
EFMJKMEB_00945 1.4e-44 V (ABC) transporter
EFMJKMEB_00946 1e-156 C Arylsulfatase regulator (Fe-S oxidoreductase)
EFMJKMEB_00950 1.2e-21 L Transposase
EFMJKMEB_00951 2.6e-52 L Transposase
EFMJKMEB_00952 5.5e-135 L integrase core domain
EFMJKMEB_00953 2.1e-30 rpsT J rRNA binding
EFMJKMEB_00954 5.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
EFMJKMEB_00955 3.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
EFMJKMEB_00956 9.3e-35 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
EFMJKMEB_00957 3e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
EFMJKMEB_00958 7.1e-59 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
EFMJKMEB_00959 2.3e-43 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
EFMJKMEB_00960 3.2e-38 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EFMJKMEB_00961 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EFMJKMEB_00962 5.8e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EFMJKMEB_00963 5.4e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EFMJKMEB_00964 8.9e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
EFMJKMEB_00965 1e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
EFMJKMEB_00966 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EFMJKMEB_00967 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EFMJKMEB_00968 3.1e-81 ypmB S Protein conserved in bacteria
EFMJKMEB_00969 1.6e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EFMJKMEB_00970 3.5e-260 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EFMJKMEB_00971 3.7e-19
EFMJKMEB_00972 3.3e-201 pmrB EGP Major facilitator Superfamily
EFMJKMEB_00973 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
EFMJKMEB_00974 2.2e-122 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EFMJKMEB_00975 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
EFMJKMEB_00976 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EFMJKMEB_00977 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
EFMJKMEB_00979 1.7e-23 yegS 2.7.1.107 I lipid kinase activity
EFMJKMEB_00982 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EFMJKMEB_00983 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EFMJKMEB_00984 9.2e-36 metE 2.1.1.14 E Methionine synthase
EFMJKMEB_00985 7.6e-64 metE 2.1.1.14 E Methionine synthase
EFMJKMEB_00986 5.7e-52 metE 2.1.1.14 E Methionine synthase
EFMJKMEB_00987 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
EFMJKMEB_00989 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EFMJKMEB_00990 9.9e-169 XK27_01785 S cog cog1284
EFMJKMEB_00991 7e-147 yaaA S Belongs to the UPF0246 family
EFMJKMEB_00992 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EFMJKMEB_00993 9.9e-91 XK27_10930 K acetyltransferase
EFMJKMEB_00994 7.5e-14
EFMJKMEB_00995 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EFMJKMEB_00996 1.7e-285 ccs S the current gene model (or a revised gene model) may contain a frame shift
EFMJKMEB_00997 4.2e-44 yrzB S Belongs to the UPF0473 family
EFMJKMEB_00998 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EFMJKMEB_00999 2.2e-44 yrzL S Belongs to the UPF0297 family
EFMJKMEB_01000 5.5e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EFMJKMEB_01001 1.1e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
EFMJKMEB_01003 2.1e-280 V ABC transporter
EFMJKMEB_01004 0.0 KLT serine threonine protein kinase
EFMJKMEB_01005 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EFMJKMEB_01007 1e-87 L Transposase
EFMJKMEB_01008 3.2e-89 L Transposase
EFMJKMEB_01009 6.9e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
EFMJKMEB_01010 4.8e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
EFMJKMEB_01011 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EFMJKMEB_01012 3.4e-120 ylfI S tigr01906
EFMJKMEB_01013 5.8e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
EFMJKMEB_01014 7.9e-10 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EFMJKMEB_01015 8.4e-88 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EFMJKMEB_01016 2e-31 XK27_08085
EFMJKMEB_01017 9.7e-43 L transposase activity
EFMJKMEB_01018 2.9e-18 L Transposase
EFMJKMEB_01019 4e-54 L Transposase and inactivated derivatives
EFMJKMEB_01020 4.2e-28 L Integrase core domain protein
EFMJKMEB_01021 4.3e-186 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EFMJKMEB_01022 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EFMJKMEB_01023 4.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EFMJKMEB_01024 5.1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EFMJKMEB_01025 7e-142 purR 2.4.2.7 F operon repressor
EFMJKMEB_01026 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
EFMJKMEB_01027 4.5e-172 rmuC S RmuC domain protein
EFMJKMEB_01028 9.2e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
EFMJKMEB_01029 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EFMJKMEB_01030 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EFMJKMEB_01032 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EFMJKMEB_01033 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EFMJKMEB_01034 4.1e-144 tatD L Hydrolase, tatd
EFMJKMEB_01035 1.9e-74 yccU S CoA-binding protein
EFMJKMEB_01036 1.1e-50 trxA O Belongs to the thioredoxin family
EFMJKMEB_01037 5.2e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EFMJKMEB_01038 1.7e-35 XK27_09805 S MORN repeat protein
EFMJKMEB_01039 0.0 XK27_09800 I Acyltransferase
EFMJKMEB_01040 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EFMJKMEB_01041 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
EFMJKMEB_01042 5.3e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EFMJKMEB_01043 2.2e-103 rplD J Forms part of the polypeptide exit tunnel
EFMJKMEB_01044 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EFMJKMEB_01045 2.6e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EFMJKMEB_01046 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EFMJKMEB_01047 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EFMJKMEB_01048 2.6e-115 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EFMJKMEB_01049 1e-69 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EFMJKMEB_01050 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
EFMJKMEB_01051 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EFMJKMEB_01052 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EFMJKMEB_01053 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EFMJKMEB_01054 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EFMJKMEB_01055 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EFMJKMEB_01056 1.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EFMJKMEB_01057 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EFMJKMEB_01058 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EFMJKMEB_01059 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EFMJKMEB_01060 2.5e-23 rpmD J ribosomal protein l30
EFMJKMEB_01061 1.3e-57 rplO J binds to the 23S rRNA
EFMJKMEB_01062 5.1e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EFMJKMEB_01063 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EFMJKMEB_01064 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EFMJKMEB_01065 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EFMJKMEB_01066 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EFMJKMEB_01067 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EFMJKMEB_01068 6.2e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFMJKMEB_01069 3.3e-62 rplQ J ribosomal protein l17
EFMJKMEB_01070 1.6e-71 L PFAM Integrase, catalytic core
EFMJKMEB_01071 2.7e-13 L PFAM Integrase, catalytic core
EFMJKMEB_01072 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
EFMJKMEB_01073 7.3e-34 6.3.2.2 H gamma-glutamylcysteine synthetase
EFMJKMEB_01074 2.1e-103 6.3.2.2 H ergothioneine biosynthetic process
EFMJKMEB_01076 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
EFMJKMEB_01079 5.7e-95 ywlG S Belongs to the UPF0340 family
EFMJKMEB_01080 3.3e-86 treR K trehalose operon
EFMJKMEB_01081 2.2e-20 treR K DNA-binding transcription factor activity
EFMJKMEB_01082 1.4e-54 treB 2.7.1.201 G PTS System
EFMJKMEB_01083 5.5e-80 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EFMJKMEB_01084 1.6e-41 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EFMJKMEB_01085 3.9e-54 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EFMJKMEB_01086 0.0 pepO 3.4.24.71 O Peptidase family M13
EFMJKMEB_01087 3.6e-64 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
EFMJKMEB_01088 2.1e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EFMJKMEB_01089 7e-66 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EFMJKMEB_01090 5.6e-29 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
EFMJKMEB_01091 7.5e-39 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EFMJKMEB_01092 1.9e-278 thrC 4.2.3.1 E Threonine synthase
EFMJKMEB_01093 2.7e-225 norN V Mate efflux family protein
EFMJKMEB_01094 1.8e-57 asp S cog cog1302
EFMJKMEB_01095 6.7e-301 yloV S kinase related to dihydroxyacetone kinase
EFMJKMEB_01096 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EFMJKMEB_01097 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
EFMJKMEB_01098 1.1e-75 ilvN 2.2.1.6 E Acetolactate synthase
EFMJKMEB_01099 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EFMJKMEB_01100 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EFMJKMEB_01101 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EFMJKMEB_01102 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFMJKMEB_01103 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFMJKMEB_01104 3.2e-67 S cog cog4699
EFMJKMEB_01105 6.4e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EFMJKMEB_01106 1e-151 cglB NU type II secretion system
EFMJKMEB_01107 2.5e-42 comGC U Required for transformation and DNA binding
EFMJKMEB_01108 2.6e-56 cglD NU Competence protein
EFMJKMEB_01109 4.1e-15 NU Type II secretory pathway pseudopilin
EFMJKMEB_01110 1.3e-70 comGF U Competence protein ComGF
EFMJKMEB_01111 2.2e-11 comGF U Putative Competence protein ComGF
EFMJKMEB_01112 4.2e-175 ytxK 2.1.1.72 L DNA methylase
EFMJKMEB_01113 3.2e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EFMJKMEB_01114 2.6e-26 lanR K sequence-specific DNA binding
EFMJKMEB_01115 1.8e-33 V CAAX protease self-immunity
EFMJKMEB_01116 1.3e-33 V CAAX protease self-immunity
EFMJKMEB_01118 9.6e-110 S CAAX amino terminal protease family protein
EFMJKMEB_01119 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFMJKMEB_01120 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EFMJKMEB_01121 1.4e-09 S Domain of unknown function (DUF4651)
EFMJKMEB_01122 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EFMJKMEB_01123 3.9e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EFMJKMEB_01124 3.6e-188 yeeE S Sulphur transport
EFMJKMEB_01125 4.1e-36 yeeD O sulfur carrier activity
EFMJKMEB_01126 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EFMJKMEB_01127 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EFMJKMEB_01130 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
EFMJKMEB_01131 1.5e-117 S HAD hydrolase, family IA, variant
EFMJKMEB_01132 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EFMJKMEB_01133 8.7e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EFMJKMEB_01134 4.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EFMJKMEB_01135 3.1e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
EFMJKMEB_01136 1.7e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EFMJKMEB_01137 7e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EFMJKMEB_01138 9e-76 XK27_08585 S Psort location CytoplasmicMembrane, score
EFMJKMEB_01139 2.1e-71 fnt P Formate nitrite transporter
EFMJKMEB_01141 4.2e-223 XK27_09615 C reductase
EFMJKMEB_01142 7.8e-35 XK27_09620 S FMN reductase (NADPH) activity
EFMJKMEB_01143 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
EFMJKMEB_01144 7e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EFMJKMEB_01145 2.4e-75 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
EFMJKMEB_01146 9.9e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EFMJKMEB_01147 1.4e-11 WQ51_05710 S Mitochondrial biogenesis AIM24
EFMJKMEB_01148 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
EFMJKMEB_01149 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
EFMJKMEB_01150 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
EFMJKMEB_01151 9.2e-51 S Protein of unknown function (DUF3397)
EFMJKMEB_01152 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EFMJKMEB_01153 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EFMJKMEB_01154 7.3e-69 amiA E transmembrane transport
EFMJKMEB_01155 6.7e-81 amiA E transmembrane transport
EFMJKMEB_01156 1.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EFMJKMEB_01157 3.4e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EFMJKMEB_01158 1.2e-263 argH 4.3.2.1 E Argininosuccinate lyase
EFMJKMEB_01159 1.3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EFMJKMEB_01160 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFMJKMEB_01161 3.2e-184 jag S RNA-binding protein
EFMJKMEB_01164 6.2e-87 repA S Replication initiator protein A
EFMJKMEB_01166 7e-13
EFMJKMEB_01167 8.6e-20 MU outer membrane autotransporter barrel domain protein
EFMJKMEB_01168 0.0 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EFMJKMEB_01169 8.9e-15
EFMJKMEB_01170 4.1e-24
EFMJKMEB_01171 1.5e-90
EFMJKMEB_01172 1.6e-42 S PrgI family protein
EFMJKMEB_01173 0.0 U Psort location Cytoplasmic, score
EFMJKMEB_01174 0.0 M CHAP domain protein
EFMJKMEB_01175 9.1e-99
EFMJKMEB_01176 3e-63 ssb L single-stranded DNA binding
EFMJKMEB_01178 8.2e-55
EFMJKMEB_01179 8e-45 S Protein of unknown function (DUF3801)
EFMJKMEB_01180 0.0 U An automated process has identified a potential problem with this gene model
EFMJKMEB_01183 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EFMJKMEB_01185 0.0 2.1.1.72, 3.1.21.3 L Psort location Cytoplasmic, score
EFMJKMEB_01187 3.7e-26 S Bacterial mobilisation protein (MobC)
EFMJKMEB_01188 2.9e-277 U relaxase
EFMJKMEB_01190 2.2e-81 tnpR L Resolvase, N terminal domain
EFMJKMEB_01192 8.6e-232 S Psort location CytoplasmicMembrane, score
EFMJKMEB_01193 9.2e-89 D CobQ CobB MinD ParA nucleotide binding domain protein
EFMJKMEB_01195 1.7e-69 M Filamentation induced by cAMP protein fic
EFMJKMEB_01196 7.9e-12 S TIR domain
EFMJKMEB_01199 1.5e-258 S Uncharacterised protein family (UPF0236)
EFMJKMEB_01200 1e-13 rpmH J Ribosomal protein L34
EFMJKMEB_01201 1.1e-83 L Transposase
EFMJKMEB_01202 2e-41 XK27_03610 K Gnat family
EFMJKMEB_01203 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EFMJKMEB_01204 9e-275 pepV 3.5.1.18 E Dipeptidase
EFMJKMEB_01205 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
EFMJKMEB_01206 3.6e-22 V Glucan-binding protein C
EFMJKMEB_01207 5.7e-08 V Glucan-binding protein C
EFMJKMEB_01209 1.9e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EFMJKMEB_01210 1.2e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EFMJKMEB_01211 1.3e-88 S Protein of unknown function (DUF1697)
EFMJKMEB_01212 1.3e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EFMJKMEB_01213 1.1e-58 clcA_2 P chloride
EFMJKMEB_01214 3.5e-56 clcA_2 P chloride
EFMJKMEB_01215 1.5e-124 yfeJ 6.3.5.2 F glutamine amidotransferase
EFMJKMEB_01216 2.6e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
EFMJKMEB_01217 1.3e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
EFMJKMEB_01218 1.1e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
EFMJKMEB_01219 1e-101 cps4C M biosynthesis protein
EFMJKMEB_01220 2.4e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
EFMJKMEB_01221 8.8e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
EFMJKMEB_01222 2.2e-23 rgpAc GT4 M group 1 family protein
EFMJKMEB_01223 1.2e-84 cpsE M Bacterial sugar transferase
EFMJKMEB_01224 3.4e-83 cpsE M Bacterial sugar transferase
EFMJKMEB_01225 4.6e-79 cpsF M Oligosaccharide biosynthesis protein Alg14 like
EFMJKMEB_01226 1.4e-70 pssE S Glycosyltransferase family 28 C-terminal domain
EFMJKMEB_01227 3.9e-96 M Glycosyltransferase sugar-binding region containing DXD motif
EFMJKMEB_01228 1.1e-17
EFMJKMEB_01229 9.2e-60 ycbI M Glycosyl transferase family 2
EFMJKMEB_01230 1e-168 M Glycosyltransferase, group 2 family protein
EFMJKMEB_01232 7.1e-18 nylA 3.5.1.4 J amidase activity
EFMJKMEB_01233 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EFMJKMEB_01234 9.1e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EFMJKMEB_01235 1.9e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EFMJKMEB_01236 4.8e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EFMJKMEB_01237 5e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
EFMJKMEB_01238 1.8e-80 S TraX protein
EFMJKMEB_01240 1.1e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EFMJKMEB_01242 3.9e-15 dinF V Mate efflux family protein
EFMJKMEB_01243 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
EFMJKMEB_01244 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
EFMJKMEB_01245 1.2e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
EFMJKMEB_01246 1.2e-143 2.4.2.3 F Phosphorylase superfamily
EFMJKMEB_01249 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
EFMJKMEB_01250 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
EFMJKMEB_01251 2.3e-07 S Hydrolases of the alpha beta superfamily
EFMJKMEB_01252 2.3e-195 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
EFMJKMEB_01253 6.7e-144 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EFMJKMEB_01254 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EFMJKMEB_01255 1.8e-159 czcD P cation diffusion facilitator family transporter
EFMJKMEB_01256 1.2e-97 K Transcriptional regulator, TetR family
EFMJKMEB_01257 1.6e-10
EFMJKMEB_01258 8.4e-112 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EFMJKMEB_01259 2.7e-116 V ABC transporter (Permease
EFMJKMEB_01260 3.8e-94 V VanZ like family
EFMJKMEB_01261 4.4e-33 G Belongs to the phosphoglycerate mutase family
EFMJKMEB_01262 8.1e-100 G Belongs to the phosphoglycerate mutase family
EFMJKMEB_01263 1e-196 S hmm pf01594
EFMJKMEB_01264 8.4e-27 bglH 3.2.1.86 GT1 G beta-glucosidase activity
EFMJKMEB_01265 7.7e-67 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFMJKMEB_01266 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
EFMJKMEB_01267 4.9e-39 S granule-associated protein
EFMJKMEB_01268 1.6e-291 S unusual protein kinase
EFMJKMEB_01269 3.4e-29 estA E Lysophospholipase L1 and related esterases
EFMJKMEB_01270 5.1e-38 estA E GDSL-like protein
EFMJKMEB_01271 4.6e-157 rssA S Phospholipase, patatin family
EFMJKMEB_01272 4.1e-127 3.4.16.4 M Belongs to the peptidase S11 family
EFMJKMEB_01273 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
EFMJKMEB_01274 5.9e-22 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EFMJKMEB_01275 5.2e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EFMJKMEB_01276 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EFMJKMEB_01277 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EFMJKMEB_01278 0.0 S the current gene model (or a revised gene model) may contain a frame shift
EFMJKMEB_01279 8.6e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EFMJKMEB_01280 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EFMJKMEB_01281 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EFMJKMEB_01282 1.5e-10 XK27_01265 S ECF-type riboflavin transporter, S component
EFMJKMEB_01283 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EFMJKMEB_01284 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EFMJKMEB_01285 2e-86 S ECF-type riboflavin transporter, S component
EFMJKMEB_01287 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFMJKMEB_01288 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
EFMJKMEB_01290 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EFMJKMEB_01291 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFMJKMEB_01292 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EFMJKMEB_01293 0.0 smc D Required for chromosome condensation and partitioning
EFMJKMEB_01294 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EFMJKMEB_01295 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EFMJKMEB_01296 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EFMJKMEB_01297 1.7e-78 alkD L Dna alkylation repair
EFMJKMEB_01298 2.8e-93 pat 2.3.1.183 M acetyltransferase
EFMJKMEB_01299 0.0 clpC O Belongs to the ClpA ClpB family
EFMJKMEB_01300 6.2e-76 ctsR K Belongs to the CtsR family
EFMJKMEB_01301 9.3e-83 S Putative small multi-drug export protein
EFMJKMEB_01302 6.6e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EFMJKMEB_01303 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
EFMJKMEB_01305 7.5e-172 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EFMJKMEB_01307 1.2e-32 L Integrase core domain protein
EFMJKMEB_01308 3.5e-97 S reductase
EFMJKMEB_01309 1.3e-54 badR K DNA-binding transcription factor activity
EFMJKMEB_01310 1.6e-35 XK27_02060 S Transglycosylase associated protein
EFMJKMEB_01311 2.1e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EFMJKMEB_01312 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFMJKMEB_01320 5.3e-11
EFMJKMEB_01332 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
EFMJKMEB_01333 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
EFMJKMEB_01334 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EFMJKMEB_01335 6.2e-56 S Domain of unknown function (DUF4430)
EFMJKMEB_01336 4.2e-75 S Psort location CytoplasmicMembrane, score
EFMJKMEB_01337 6.4e-133 htpX O Belongs to the peptidase M48B family
EFMJKMEB_01338 2.6e-92 lemA S LemA family
EFMJKMEB_01339 1.7e-171 spd F DNA RNA non-specific endonuclease
EFMJKMEB_01340 2.3e-48 S double-stranded DNA endodeoxyribonuclease activity
EFMJKMEB_01341 4.3e-305 hsdM 2.1.1.72 V type I restriction-modification system
EFMJKMEB_01342 5.6e-130 S Protein conserved in bacteria
EFMJKMEB_01343 0.0 S KAP family P-loop domain
EFMJKMEB_01344 2.2e-120 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
EFMJKMEB_01345 1.3e-17
EFMJKMEB_01346 3.2e-89 L Transposase
EFMJKMEB_01348 9.2e-53
EFMJKMEB_01349 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EFMJKMEB_01350 7.4e-130 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EFMJKMEB_01351 2.2e-48 MA20_36090 S Protein of unknown function (DUF2974)
EFMJKMEB_01352 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
EFMJKMEB_01353 2.6e-112 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFMJKMEB_01354 2.7e-27 P Hemerythrin HHE cation binding domain protein
EFMJKMEB_01355 4.5e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
EFMJKMEB_01356 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EFMJKMEB_01357 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
EFMJKMEB_01358 6.4e-173 S hydrolase
EFMJKMEB_01359 3.5e-19
EFMJKMEB_01360 2.4e-58 M LysM domain
EFMJKMEB_01361 1.9e-15 M LysM domain
EFMJKMEB_01362 3.5e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EFMJKMEB_01363 1.6e-07 S Type-A lantibiotic
EFMJKMEB_01365 0.0 lcnDR2 V Domain of unknown function (DUF4135)
EFMJKMEB_01366 0.0 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EFMJKMEB_01367 2e-166 bcrA V abc transporter atp-binding protein
EFMJKMEB_01368 1.6e-129 S ABC-2 family transporter protein
EFMJKMEB_01369 1.7e-123 S ABC-2 family transporter protein
EFMJKMEB_01370 1.3e-34 K transcriptional
EFMJKMEB_01371 0.0 L Recombinase zinc beta ribbon domain
EFMJKMEB_01372 6e-55 J Acetyltransferase (GNAT) domain
EFMJKMEB_01373 5.7e-95
EFMJKMEB_01374 3.2e-89 L Transposase
EFMJKMEB_01375 1.2e-88 L Transposase
EFMJKMEB_01376 6.3e-07
EFMJKMEB_01377 6.9e-19
EFMJKMEB_01379 1.9e-09
EFMJKMEB_01380 2.5e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EFMJKMEB_01381 1.1e-130 ecsA V abc transporter atp-binding protein
EFMJKMEB_01382 4.3e-181 ecsB U ABC transporter
EFMJKMEB_01383 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
EFMJKMEB_01384 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EFMJKMEB_01386 1e-226 ytfP S Flavoprotein
EFMJKMEB_01387 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EFMJKMEB_01388 4.8e-63 XK27_02560 S cog cog2151
EFMJKMEB_01389 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
EFMJKMEB_01390 1.3e-102 dnaQ 2.7.7.7 L DNA polymerase III
EFMJKMEB_01391 6e-121 K transcriptional regulator, MerR family
EFMJKMEB_01392 5.1e-47 L transposase activity
EFMJKMEB_01393 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EFMJKMEB_01394 8e-42 K Cold-Shock Protein
EFMJKMEB_01395 9.3e-32 cspD K Cold shock protein domain
EFMJKMEB_01396 2.4e-27
EFMJKMEB_01398 7.1e-28 L transposase activity
EFMJKMEB_01399 9.9e-64 tnp L DDE domain
EFMJKMEB_01400 2.6e-44 pepD E Dipeptidase
EFMJKMEB_01401 5.8e-77 pepD E Dipeptidase
EFMJKMEB_01402 7.2e-25 pepD E Dipeptidase
EFMJKMEB_01403 1.9e-161 whiA K May be required for sporulation
EFMJKMEB_01404 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EFMJKMEB_01405 4.5e-163 rapZ S Displays ATPase and GTPase activities
EFMJKMEB_01406 8.5e-134 yejC S cyclic nucleotide-binding protein
EFMJKMEB_01407 3.6e-17 D nuclear chromosome segregation
EFMJKMEB_01408 8.3e-160 4.1.3.39 E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds
EFMJKMEB_01410 4e-209 dlpA 1.1.1.85 CE Tartrate dehydrogenase
EFMJKMEB_01411 7.7e-123 dlpA H Methyltransferase
EFMJKMEB_01412 6.8e-153 S metal-dependent hydrolase with the TIM-barrel fold
EFMJKMEB_01413 1.2e-71 2.7.7.12 C Domain of unknown function (DUF4931)
EFMJKMEB_01414 6.3e-160 yrdR EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EFMJKMEB_01415 4.7e-16 K helix_turn_helix, Arsenical Resistance Operon Repressor
EFMJKMEB_01416 2.4e-13 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
EFMJKMEB_01417 5.1e-21 L overlaps another CDS with the same product name
EFMJKMEB_01418 7.4e-135 agrA KT phosphorelay signal transduction system
EFMJKMEB_01419 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
EFMJKMEB_01421 7.3e-237 mesE M Transport protein ComB
EFMJKMEB_01422 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EFMJKMEB_01423 0.0 mdlB V abc transporter atp-binding protein
EFMJKMEB_01424 0.0 mdlA V abc transporter atp-binding protein
EFMJKMEB_01426 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
EFMJKMEB_01427 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EFMJKMEB_01428 2.4e-66 yutD J protein conserved in bacteria
EFMJKMEB_01429 9e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EFMJKMEB_01431 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EFMJKMEB_01432 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EFMJKMEB_01433 0.0 ftsI 3.4.16.4 M penicillin-binding protein
EFMJKMEB_01434 4.3e-47 ftsL D cell division protein FtsL
EFMJKMEB_01435 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EFMJKMEB_01436 1.6e-65
EFMJKMEB_01437 7.4e-27
EFMJKMEB_01438 7.5e-30
EFMJKMEB_01439 8.7e-33 yhaI J Protein of unknown function (DUF805)
EFMJKMEB_01440 4.5e-18 D nuclear chromosome segregation
EFMJKMEB_01441 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EFMJKMEB_01442 2.6e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EFMJKMEB_01443 2e-286 XK27_00765
EFMJKMEB_01444 8.1e-134 ecsA_2 V abc transporter atp-binding protein
EFMJKMEB_01445 7.6e-12 S Protein of unknown function (DUF554)
EFMJKMEB_01446 3.1e-99 S Protein of unknown function (DUF554)
EFMJKMEB_01447 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EFMJKMEB_01448 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EFMJKMEB_01449 2.4e-55 liaI S membrane
EFMJKMEB_01450 2.7e-09 XK27_02470 K LytTr DNA-binding domain protein
EFMJKMEB_01451 3e-53 KT response to antibiotic
EFMJKMEB_01452 1.4e-08 KT response to antibiotic
EFMJKMEB_01453 9.1e-18 KT response to antibiotic
EFMJKMEB_01454 9.8e-80 yebC M Membrane
EFMJKMEB_01455 1.1e-16 yebC M Membrane
EFMJKMEB_01456 1.2e-258 XK27_03190 S hydrolases of the HAD superfamily
EFMJKMEB_01457 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EFMJKMEB_01458 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EFMJKMEB_01459 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EFMJKMEB_01460 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EFMJKMEB_01461 2.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EFMJKMEB_01462 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EFMJKMEB_01463 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EFMJKMEB_01465 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
EFMJKMEB_01466 5.2e-130 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
EFMJKMEB_01467 7e-124 tnp L DDE domain
EFMJKMEB_01468 5.6e-34 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
EFMJKMEB_01469 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
EFMJKMEB_01470 2.7e-290 scrB 3.2.1.26 GH32 G invertase
EFMJKMEB_01471 2.4e-178 scrR K Transcriptional
EFMJKMEB_01472 3.6e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EFMJKMEB_01473 3.4e-62 yqhY S protein conserved in bacteria
EFMJKMEB_01474 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EFMJKMEB_01475 1.1e-83 comEB 3.5.4.12 F ComE operon protein 2
EFMJKMEB_01476 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
EFMJKMEB_01479 6.9e-12 V 'abc transporter, ATP-binding protein
EFMJKMEB_01480 1.3e-58 V 'abc transporter, ATP-binding protein
EFMJKMEB_01486 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EFMJKMEB_01487 5e-168 corA P COG0598 Mg2 and Co2 transporters
EFMJKMEB_01488 2e-123 XK27_01040 S Pfam PF06570
EFMJKMEB_01490 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EFMJKMEB_01491 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EFMJKMEB_01492 1.9e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
EFMJKMEB_01493 2.8e-41 XK27_05745
EFMJKMEB_01494 2.3e-228 mutY L A G-specific adenine glycosylase
EFMJKMEB_01498 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EFMJKMEB_01499 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EFMJKMEB_01500 1e-93 cvpA S toxin biosynthetic process
EFMJKMEB_01501 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EFMJKMEB_01502 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFMJKMEB_01503 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EFMJKMEB_01504 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EFMJKMEB_01505 8.8e-48 azlD E branched-chain amino acid
EFMJKMEB_01506 8.5e-117 azlC E AzlC protein
EFMJKMEB_01507 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EFMJKMEB_01508 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EFMJKMEB_01509 2.1e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
EFMJKMEB_01510 2.5e-33 ykzG S Belongs to the UPF0356 family
EFMJKMEB_01511 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EFMJKMEB_01512 7.1e-41 pscB M CHAP domain protein
EFMJKMEB_01514 9.9e-263 glnA 6.3.1.2 E glutamine synthetase
EFMJKMEB_01515 8.5e-63 glnR K Transcriptional regulator
EFMJKMEB_01516 1.3e-87 S Fusaric acid resistance protein-like
EFMJKMEB_01517 1.5e-12
EFMJKMEB_01518 1.7e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EFMJKMEB_01519 7.6e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EFMJKMEB_01520 0.0 sbcC L ATPase involved in DNA repair
EFMJKMEB_01521 1e-31
EFMJKMEB_01522 9e-44 L COG2963 Transposase and inactivated derivatives
EFMJKMEB_01523 1.5e-21 L Transposase and inactivated derivatives
EFMJKMEB_01524 1.5e-39 L transposition
EFMJKMEB_01525 2.2e-17
EFMJKMEB_01529 9.5e-140 blpT
EFMJKMEB_01530 3e-47 spiA K sequence-specific DNA binding
EFMJKMEB_01533 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EFMJKMEB_01534 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EFMJKMEB_01535 1.8e-156 oppF P Belongs to the ABC transporter superfamily
EFMJKMEB_01536 7.1e-203 oppD P Belongs to the ABC transporter superfamily
EFMJKMEB_01537 3.1e-167 amiD P ABC transporter (Permease
EFMJKMEB_01538 4.2e-270 amiC P ABC transporter (Permease
EFMJKMEB_01539 2.1e-233 amiA E ABC transporter, substrate-binding protein, family 5
EFMJKMEB_01540 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
EFMJKMEB_01541 2.2e-186 yxaM EGP Major facilitator Superfamily
EFMJKMEB_01542 1.1e-89 adk 2.7.4.3 F topology modulation protein
EFMJKMEB_01543 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EFMJKMEB_01546 4.1e-195 wbbI M transferase activity, transferring glycosyl groups
EFMJKMEB_01547 2.1e-57 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
EFMJKMEB_01548 5.4e-68 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
EFMJKMEB_01549 4.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
EFMJKMEB_01550 2e-242 epsU S Polysaccharide biosynthesis protein
EFMJKMEB_01551 6e-88 L Transposase
EFMJKMEB_01552 0.0 copB 3.6.3.4 P COG2217 Cation transport ATPase
EFMJKMEB_01553 3.2e-89 L Transposase
EFMJKMEB_01554 1.7e-99
EFMJKMEB_01555 1.8e-23 S Small integral membrane protein
EFMJKMEB_01556 6.5e-83 M Protein conserved in bacteria
EFMJKMEB_01557 1.1e-11 K CsbD-like
EFMJKMEB_01558 1.1e-107 nudL L hydrolase
EFMJKMEB_01559 3.2e-89 L Transposase
EFMJKMEB_01560 8.4e-51 tnp L Transposase IS66 family
EFMJKMEB_01561 5.5e-65 dhaL 2.7.1.121 G Dihydroxyacetone kinase
EFMJKMEB_01562 3.3e-247 G polysaccharide deacetylase
EFMJKMEB_01563 1.3e-31 L PFAM Integrase catalytic region
EFMJKMEB_01564 9.9e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
EFMJKMEB_01565 1.4e-40 tatD L Hydrolase, tatd
EFMJKMEB_01566 5e-45 oppF P Belongs to the ABC transporter superfamily
EFMJKMEB_01567 4.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
EFMJKMEB_01568 2.8e-230 ytoI K transcriptional regulator containing CBS domains
EFMJKMEB_01569 7.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
EFMJKMEB_01570 2.4e-159 rbn E Belongs to the UPF0761 family
EFMJKMEB_01571 1.3e-85 ccl S cog cog4708
EFMJKMEB_01572 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EFMJKMEB_01573 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EFMJKMEB_01574 1.7e-119 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
EFMJKMEB_01575 2.1e-74 S QueT transporter
EFMJKMEB_01576 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
EFMJKMEB_01577 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
EFMJKMEB_01578 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EFMJKMEB_01579 4.1e-37 ylqC L Belongs to the UPF0109 family
EFMJKMEB_01580 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EFMJKMEB_01581 0.0 ydaO E amino acid
EFMJKMEB_01582 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
EFMJKMEB_01583 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EFMJKMEB_01584 3e-297 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EFMJKMEB_01585 7.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EFMJKMEB_01586 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EFMJKMEB_01587 7.8e-171 murB 1.3.1.98 M cell wall formation
EFMJKMEB_01588 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EFMJKMEB_01589 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
EFMJKMEB_01590 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
EFMJKMEB_01591 2.3e-206 potD P spermidine putrescine ABC transporter
EFMJKMEB_01593 4.5e-21 XK27_08050 O HflC and HflK could regulate a protease
EFMJKMEB_01594 7.4e-90
EFMJKMEB_01595 1.9e-107
EFMJKMEB_01597 1.8e-87 L transposase activity
EFMJKMEB_01598 1.4e-150 L Integrase core domain protein
EFMJKMEB_01599 3.2e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EFMJKMEB_01601 5.5e-258 I radical SAM domain protein
EFMJKMEB_01602 1.2e-176 EGP Major Facilitator Superfamily
EFMJKMEB_01603 3.9e-110 C Fe-S oxidoreductases
EFMJKMEB_01605 4.3e-167 V MatE
EFMJKMEB_01606 1.1e-12
EFMJKMEB_01607 7.5e-09 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EFMJKMEB_01608 2e-29 K Helix-turn-helix XRE-family like proteins
EFMJKMEB_01609 7.3e-51 S Toxin-antitoxin system, toxin component, RelE family
EFMJKMEB_01611 3.9e-75 XK27_01300 S ASCH
EFMJKMEB_01612 6.2e-13 XK27_08050 O HflC and HflK could regulate a protease
EFMJKMEB_01613 6.6e-62 XK27_08050 O stress-induced mitochondrial fusion
EFMJKMEB_01614 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
EFMJKMEB_01615 1.6e-12 GK ROK family
EFMJKMEB_01616 1.2e-45 GK ROK family
EFMJKMEB_01617 5.1e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EFMJKMEB_01618 1.3e-104 wecD M Acetyltransferase (GNAT) domain
EFMJKMEB_01619 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFMJKMEB_01620 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
EFMJKMEB_01621 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
EFMJKMEB_01623 7.7e-56 lrgA S Effector of murein hydrolase LrgA
EFMJKMEB_01624 2.2e-117 lrgB M effector of murein hydrolase
EFMJKMEB_01625 1.6e-97 3.1.3.18 S IA, variant 1
EFMJKMEB_01626 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFMJKMEB_01627 9.6e-303 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EFMJKMEB_01628 5.3e-113 serB 3.1.3.3 E phosphoserine phosphatase
EFMJKMEB_01630 3.2e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
EFMJKMEB_01632 6.7e-50 ycaO O OsmC-like protein
EFMJKMEB_01633 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
EFMJKMEB_01636 3.1e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EFMJKMEB_01638 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EFMJKMEB_01639 1.1e-16 XK27_00735
EFMJKMEB_01640 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
EFMJKMEB_01641 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
EFMJKMEB_01642 2.4e-33 S CAAX amino terminal protease family protein
EFMJKMEB_01643 4.3e-82 S CAAX amino terminal protease family protein
EFMJKMEB_01645 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EFMJKMEB_01646 2.9e-84 mutT 3.6.1.55 F Nudix family
EFMJKMEB_01647 1.7e-140 ET Belongs to the bacterial solute-binding protein 3 family
EFMJKMEB_01648 4.7e-135 ET ABC transporter
EFMJKMEB_01649 7.5e-200 arcT 2.6.1.1 E Aminotransferase
EFMJKMEB_01650 4.2e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
EFMJKMEB_01651 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EFMJKMEB_01652 4.3e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EFMJKMEB_01653 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EFMJKMEB_01654 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EFMJKMEB_01655 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
EFMJKMEB_01656 1.8e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EFMJKMEB_01657 1.9e-245
EFMJKMEB_01658 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EFMJKMEB_01659 2.2e-125 ycbB S Glycosyl transferase family 2
EFMJKMEB_01660 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
EFMJKMEB_01661 5.8e-220 amrA S polysaccharide biosynthetic process
EFMJKMEB_01662 2.6e-183 tagF 2.7.8.12 M Glycosyl transferase, family 2
EFMJKMEB_01663 6.4e-141 S Predicted membrane protein (DUF2142)
EFMJKMEB_01664 3.5e-224 rgpA GT4 M Domain of unknown function (DUF1972)
EFMJKMEB_01665 6.3e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
EFMJKMEB_01666 1.4e-142 rgpC GM Transport permease protein
EFMJKMEB_01667 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EFMJKMEB_01668 3.1e-195 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EFMJKMEB_01669 0.0 rgpF M Rhamnan synthesis protein F
EFMJKMEB_01670 3.9e-114 radC E Belongs to the UPF0758 family
EFMJKMEB_01671 2.7e-123 puuD T peptidase C26
EFMJKMEB_01672 6.3e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EFMJKMEB_01673 1.2e-58 XK27_04120 S Putative amino acid metabolism
EFMJKMEB_01674 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
EFMJKMEB_01675 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EFMJKMEB_01676 1.5e-103 yjbK S Adenylate cyclase
EFMJKMEB_01677 1.4e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
EFMJKMEB_01678 3.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EFMJKMEB_01679 2.8e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EFMJKMEB_01680 2.9e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EFMJKMEB_01681 3.5e-106 MA20_06410 E LysE type translocator
EFMJKMEB_01682 1.9e-69 IQ PFAM AMP-dependent synthetase and ligase
EFMJKMEB_01687 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
EFMJKMEB_01688 8.5e-22 L Transposase for ISSha1
EFMJKMEB_01689 2.9e-48 U response to pH
EFMJKMEB_01690 6.5e-108 L Transposase
EFMJKMEB_01691 6.3e-85 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
EFMJKMEB_01692 3e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
EFMJKMEB_01693 7.8e-143 S Macro domain protein
EFMJKMEB_01694 1.8e-10 L thioesterase
EFMJKMEB_01695 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
EFMJKMEB_01696 3.2e-89 L Transposase
EFMJKMEB_01697 1e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
EFMJKMEB_01698 9.1e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EFMJKMEB_01699 7.9e-100 K sequence-specific DNA binding
EFMJKMEB_01700 2e-11 C Arylsulfatase regulator (Fe-S oxidoreductase)
EFMJKMEB_01701 8.5e-09
EFMJKMEB_01702 3.3e-30 S Antidote-toxin recognition MazE, bacterial antitoxin
EFMJKMEB_01703 1e-69 doc S Prophage maintenance system killer protein
EFMJKMEB_01704 3.6e-16
EFMJKMEB_01705 2.1e-134 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylase
EFMJKMEB_01706 8.7e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EFMJKMEB_01707 2.2e-185 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EFMJKMEB_01708 0.0 dnaE 2.7.7.7 L DNA polymerase
EFMJKMEB_01709 1.3e-150 sua5 2.7.7.87 J Belongs to the SUA5 family
EFMJKMEB_01710 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EFMJKMEB_01711 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EFMJKMEB_01712 2.5e-43 ysdA L Membrane
EFMJKMEB_01713 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EFMJKMEB_01714 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EFMJKMEB_01715 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EFMJKMEB_01716 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
EFMJKMEB_01718 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EFMJKMEB_01719 1.3e-91 ypmS S Protein conserved in bacteria
EFMJKMEB_01720 1.3e-85 ypmR E lipolytic protein G-D-S-L family
EFMJKMEB_01721 3.8e-45 ypmR E COG2755 Lysophospholipase L1 and related esterases
EFMJKMEB_01722 3.3e-147 DegV S DegV family
EFMJKMEB_01723 2.9e-304 recN L May be involved in recombinational repair of damaged DNA
EFMJKMEB_01724 3.7e-73 argR K Regulates arginine biosynthesis genes
EFMJKMEB_01725 4.7e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EFMJKMEB_01726 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EFMJKMEB_01727 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
EFMJKMEB_01728 3.4e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EFMJKMEB_01729 2.5e-07 KT response to antibiotic
EFMJKMEB_01731 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EFMJKMEB_01732 1.5e-124 dnaD
EFMJKMEB_01733 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EFMJKMEB_01734 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EFMJKMEB_01735 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
EFMJKMEB_01736 9.7e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EFMJKMEB_01737 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EFMJKMEB_01738 3.9e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EFMJKMEB_01739 2.7e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EFMJKMEB_01740 7.3e-232 rodA D Belongs to the SEDS family
EFMJKMEB_01741 2e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
EFMJKMEB_01742 8e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EFMJKMEB_01743 2e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EFMJKMEB_01744 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EFMJKMEB_01745 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EFMJKMEB_01746 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EFMJKMEB_01747 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EFMJKMEB_01748 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EFMJKMEB_01749 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EFMJKMEB_01750 6.9e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EFMJKMEB_01751 8.1e-45 L Transposase
EFMJKMEB_01752 4.1e-158 L COG2801 Transposase and inactivated derivatives
EFMJKMEB_01753 9.4e-139 S dextransucrase activity
EFMJKMEB_01754 8.8e-39 S dextransucrase activity
EFMJKMEB_01755 6.3e-14 S dextransucrase activity
EFMJKMEB_01756 4e-69 S dextransucrase activity
EFMJKMEB_01757 1.1e-227 yfnA E amino acid
EFMJKMEB_01758 4.8e-25 csbD K CsbD-like
EFMJKMEB_01759 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
EFMJKMEB_01760 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
EFMJKMEB_01761 6.6e-235 brnQ E Component of the transport system for branched-chain amino acids
EFMJKMEB_01762 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EFMJKMEB_01763 4.5e-247 norM V Multidrug efflux pump
EFMJKMEB_01764 9.2e-119 pbuX F xanthine permease
EFMJKMEB_01765 3.3e-69 pbuX F xanthine permease
EFMJKMEB_01766 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EFMJKMEB_01767 2e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFMJKMEB_01768 6.2e-166 T Histidine kinase
EFMJKMEB_01769 1.9e-133 macB2 V ABC transporter, ATP-binding protein
EFMJKMEB_01770 0.0 V ABC transporter (permease)
EFMJKMEB_01771 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
EFMJKMEB_01772 5.8e-30 liaI KT membrane
EFMJKMEB_01773 1.6e-14 liaI KT membrane
EFMJKMEB_01774 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
EFMJKMEB_01775 3.7e-122 S An automated process has identified a potential problem with this gene model
EFMJKMEB_01777 4.6e-42 3.6.1.55 F NUDIX domain
EFMJKMEB_01778 7.9e-152 mutR K Transcriptional activator, Rgg GadR MutR family
EFMJKMEB_01779 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
EFMJKMEB_01780 3.3e-212 EGP Major facilitator Superfamily
EFMJKMEB_01784 7.4e-158 XK27_09825 V abc transporter atp-binding protein
EFMJKMEB_01785 2.6e-132 yvfS V ABC-2 type transporter
EFMJKMEB_01786 6e-186 desK 2.7.13.3 T Histidine kinase
EFMJKMEB_01787 1.3e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFMJKMEB_01788 4.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
EFMJKMEB_01789 2.5e-308 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EFMJKMEB_01790 1.6e-205 S Protein of unknown function (DUF917)
EFMJKMEB_01791 2.5e-278 hutH 4.3.1.3 E Histidine ammonia-lyase
EFMJKMEB_01792 2.3e-103 proWZ P ABC transporter (Permease
EFMJKMEB_01793 3.8e-165 proX M ABC transporter, substrate-binding protein, QAT family
EFMJKMEB_01794 1.6e-137 proV E abc transporter atp-binding protein
EFMJKMEB_01795 2e-88 proW P Binding-protein-dependent transport system inner membrane component
EFMJKMEB_01796 1.6e-20 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
EFMJKMEB_01797 3.9e-37 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
EFMJKMEB_01798 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EFMJKMEB_01799 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EFMJKMEB_01800 1.8e-79 tnpR L Resolvase, N terminal domain
EFMJKMEB_01801 2.3e-27 S Protein of unknown function (DUF2568)
EFMJKMEB_01807 2.6e-10
EFMJKMEB_01808 2.6e-64 WQ51_03320 S cog cog4835
EFMJKMEB_01809 2.4e-44 XK27_08360 S EDD domain protein, DegV family
EFMJKMEB_01810 7.8e-86 XK27_08360 T EDD domain protein, DegV family
EFMJKMEB_01811 4.3e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EFMJKMEB_01812 9e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EFMJKMEB_01813 0.0 yfmR S abc transporter atp-binding protein
EFMJKMEB_01814 3.3e-25 U response to pH
EFMJKMEB_01815 3e-139 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
EFMJKMEB_01816 3.4e-208 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
EFMJKMEB_01817 6.9e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
EFMJKMEB_01818 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EFMJKMEB_01819 1.6e-76 K DNA-binding transcription factor activity
EFMJKMEB_01820 0.0 lmrA1 V abc transporter atp-binding protein
EFMJKMEB_01821 0.0 lmrA2 V abc transporter atp-binding protein
EFMJKMEB_01822 1.1e-49 K Acetyltransferase (GNAT) family
EFMJKMEB_01823 2.7e-27 2.7.6.5 S Region found in RelA / SpoT proteins
EFMJKMEB_01824 2.6e-28 2.7.6.5 S Region found in RelA / SpoT proteins
EFMJKMEB_01825 7.9e-32 T response regulator
EFMJKMEB_01826 2.8e-28 T response regulator
EFMJKMEB_01828 1.1e-13 sptS 2.7.13.3 T Histidine kinase
EFMJKMEB_01829 4.3e-107 sptS 2.7.13.3 T Histidine kinase
EFMJKMEB_01830 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EFMJKMEB_01831 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EFMJKMEB_01832 7e-161 cvfB S Protein conserved in bacteria
EFMJKMEB_01833 7.4e-35 yozE S Belongs to the UPF0346 family
EFMJKMEB_01834 4.2e-120 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
EFMJKMEB_01835 2.6e-61 rlpA M LysM domain protein
EFMJKMEB_01836 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
EFMJKMEB_01840 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EFMJKMEB_01841 9.2e-164 K transcriptional regulator (lysR family)
EFMJKMEB_01842 1.4e-186 coiA 3.6.4.12 S Competence protein
EFMJKMEB_01843 0.0 pepF E oligoendopeptidase F
EFMJKMEB_01844 7.1e-127 yrrM 2.1.1.104 S O-Methyltransferase
EFMJKMEB_01845 3.9e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
EFMJKMEB_01846 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EFMJKMEB_01847 2.5e-146 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EFMJKMEB_01848 1.9e-39 3.4.17.14, 3.5.1.28 NU amidase activity
EFMJKMEB_01849 1.3e-30 3.4.17.14, 3.5.1.28 NU amidase activity
EFMJKMEB_01850 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EFMJKMEB_01851 1.5e-225 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
EFMJKMEB_01852 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EFMJKMEB_01853 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EFMJKMEB_01854 1.3e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EFMJKMEB_01855 4.5e-208 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EFMJKMEB_01856 3.6e-128 yxkH G deacetylase
EFMJKMEB_01857 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EFMJKMEB_01858 2.1e-149 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EFMJKMEB_01859 1e-151 rarD S Transporter
EFMJKMEB_01860 2.6e-16 T peptidase
EFMJKMEB_01861 8.9e-14 coiA 3.6.4.12 S Competence protein
EFMJKMEB_01862 2.3e-99 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EFMJKMEB_01863 1.1e-96 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
EFMJKMEB_01864 2.5e-16 endA F DNA/RNA non-specific endonuclease
EFMJKMEB_01865 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EFMJKMEB_01866 1.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFMJKMEB_01867 1.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
EFMJKMEB_01868 2.3e-76 atpF C ATP synthase F(0) sector subunit b
EFMJKMEB_01869 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFMJKMEB_01870 2.5e-278 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EFMJKMEB_01871 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EFMJKMEB_01872 3.9e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EFMJKMEB_01873 2e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EFMJKMEB_01874 7.5e-228 ftsW D Belongs to the SEDS family
EFMJKMEB_01875 3.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EFMJKMEB_01876 3.4e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EFMJKMEB_01877 3.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EFMJKMEB_01878 1.1e-156 holB 2.7.7.7 L dna polymerase iii
EFMJKMEB_01879 8e-135 yaaT S stage 0 sporulation protein
EFMJKMEB_01880 2.8e-54 yabA L Involved in initiation control of chromosome replication
EFMJKMEB_01881 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EFMJKMEB_01882 1.6e-77 sigH K DNA-templated transcription, initiation
EFMJKMEB_01883 1.6e-146 ykuT M mechanosensitive ion channel
EFMJKMEB_01884 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EFMJKMEB_01885 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EFMJKMEB_01886 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EFMJKMEB_01887 4.2e-83 XK27_03960 S Protein of unknown function (DUF3013)
EFMJKMEB_01888 3.1e-80 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
EFMJKMEB_01889 1.3e-176 prmA J Ribosomal protein L11 methyltransferase
EFMJKMEB_01890 3.7e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EFMJKMEB_01891 1.5e-35 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EFMJKMEB_01892 8.6e-45 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EFMJKMEB_01893 2.1e-21 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EFMJKMEB_01894 1e-241 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EFMJKMEB_01895 5.3e-83 nrdI F Belongs to the NrdI family
EFMJKMEB_01896 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EFMJKMEB_01897 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EFMJKMEB_01898 2e-08 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EFMJKMEB_01899 3e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EFMJKMEB_01900 2.3e-18 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EFMJKMEB_01901 1.7e-39 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EFMJKMEB_01902 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EFMJKMEB_01903 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EFMJKMEB_01904 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EFMJKMEB_01905 1.4e-201 yhjX P Major Facilitator
EFMJKMEB_01906 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EFMJKMEB_01907 5e-94 V VanZ like family
EFMJKMEB_01910 1e-123 glnQ E abc transporter atp-binding protein
EFMJKMEB_01911 1.8e-276 glnP P ABC transporter
EFMJKMEB_01912 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EFMJKMEB_01913 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EFMJKMEB_01914 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
EFMJKMEB_01915 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EFMJKMEB_01916 6.3e-235 sufD O assembly protein SufD
EFMJKMEB_01917 2.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EFMJKMEB_01918 4.7e-73 nifU C SUF system FeS assembly protein, NifU family
EFMJKMEB_01919 2.2e-273 sufB O assembly protein SufB
EFMJKMEB_01920 9.7e-19 oppA E ABC transporter substrate-binding protein
EFMJKMEB_01921 8.8e-139 oppA E ABC transporter substrate-binding protein
EFMJKMEB_01922 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFMJKMEB_01924 6.2e-61 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFMJKMEB_01925 7.3e-189 oppD P Belongs to the ABC transporter superfamily
EFMJKMEB_01926 8.1e-163 oppF P Belongs to the ABC transporter superfamily
EFMJKMEB_01928 5.6e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EFMJKMEB_01929 1.3e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EFMJKMEB_01930 6e-128 K sequence-specific DNA binding
EFMJKMEB_01931 1.5e-106 KLT serine threonine protein kinase
EFMJKMEB_01932 0.0 KLT serine threonine protein kinase
EFMJKMEB_01933 1.9e-223 EGP Major facilitator Superfamily
EFMJKMEB_01934 3.1e-72 adcR K transcriptional
EFMJKMEB_01935 2.2e-136 adcC P ABC transporter, ATP-binding protein
EFMJKMEB_01936 1.9e-128 adcB P ABC transporter (Permease
EFMJKMEB_01937 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
EFMJKMEB_01938 1.3e-64 ptsG 2.7.1.199, 2.7.1.208 G pts system
EFMJKMEB_01939 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
EFMJKMEB_01940 4.2e-257 ptsG 2.7.1.199, 2.7.1.208 G pts system
EFMJKMEB_01941 9.8e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
EFMJKMEB_01942 3.4e-255 pgi 5.3.1.9 G Belongs to the GPI family
EFMJKMEB_01943 1.2e-126 yeeN K transcriptional regulatory protein
EFMJKMEB_01944 9.8e-50 yajC U protein transport
EFMJKMEB_01945 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EFMJKMEB_01946 5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
EFMJKMEB_01947 1e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EFMJKMEB_01948 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EFMJKMEB_01949 0.0 WQ51_06230 S ABC transporter substrate binding protein
EFMJKMEB_01950 1.3e-140 cmpC S abc transporter atp-binding protein
EFMJKMEB_01951 1e-39 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EFMJKMEB_01952 2.5e-284 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EFMJKMEB_01954 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
EFMJKMEB_01955 1.1e-33 XK27_12190 S protein conserved in bacteria
EFMJKMEB_01957 2.1e-86 bioY S biotin synthase
EFMJKMEB_01958 3.4e-252 yegQ O Peptidase U32
EFMJKMEB_01959 1.7e-176 yegQ O Peptidase U32
EFMJKMEB_01961 1.2e-68 ytxH S General stress protein
EFMJKMEB_01963 3.1e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EFMJKMEB_01964 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EFMJKMEB_01965 6.4e-41 pspC KT PspC domain
EFMJKMEB_01966 0.0 yhgF K Transcriptional accessory protein
EFMJKMEB_01968 1.6e-155 XK27_03015 S permease
EFMJKMEB_01969 3.5e-146 ycgQ S TIGR03943 family
EFMJKMEB_01970 5.9e-186 S CRISPR-associated protein Csn2 subfamily St
EFMJKMEB_01971 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFMJKMEB_01972 5.5e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFMJKMEB_01973 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EFMJKMEB_01974 2.1e-95
EFMJKMEB_01975 1.9e-27 estA E GDSL-like Lipase/Acylhydrolase
EFMJKMEB_01976 1e-30 S CAAX protease self-immunity
EFMJKMEB_01977 1.7e-26 S CAAX protease self-immunity
EFMJKMEB_01978 2.4e-33
EFMJKMEB_01980 3.3e-64 yqeB S Pyrimidine dimer DNA glycosylase
EFMJKMEB_01981 7.8e-59 S Protein of unknown function (DUF1722)
EFMJKMEB_01982 8.9e-11
EFMJKMEB_01983 3e-25 L COG2801 Transposase and inactivated derivatives
EFMJKMEB_01984 5.6e-68 L transposition
EFMJKMEB_01985 1.5e-37 L transposase activity
EFMJKMEB_01986 0.0 M family 8
EFMJKMEB_01987 3e-292 hsdM 2.1.1.72 V Type I restriction-modification system
EFMJKMEB_01988 1.6e-73 3.1.21.3 V Type I restriction modification DNA specificity domain
EFMJKMEB_01989 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EFMJKMEB_01990 2.9e-16
EFMJKMEB_01991 6.5e-117
EFMJKMEB_01992 2.5e-264 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFMJKMEB_01993 3.2e-59
EFMJKMEB_01995 2.6e-31 S Signal peptide protein, YSIRK family
EFMJKMEB_01996 2.5e-31 S Signal peptide protein, YSIRK family
EFMJKMEB_01997 4.8e-55 K response regulator
EFMJKMEB_01999 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
EFMJKMEB_02000 7.5e-180 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EFMJKMEB_02001 6.8e-161 yvgN C reductase
EFMJKMEB_02002 9.9e-98 yoaK S Protein of unknown function (DUF1275)
EFMJKMEB_02003 1.4e-110 drgA C Nitroreductase
EFMJKMEB_02004 4.3e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EFMJKMEB_02005 1.3e-154 E Alpha/beta hydrolase of unknown function (DUF915)
EFMJKMEB_02006 3.6e-76 ywnA K Transcriptional regulator
EFMJKMEB_02007 2.7e-149 1.13.11.2 S glyoxalase
EFMJKMEB_02008 7.4e-109 XK27_02070 S nitroreductase
EFMJKMEB_02010 2.1e-71 ydhF S Aldo keto reductase
EFMJKMEB_02011 9.4e-68 ydhF S Aldo keto reductase
EFMJKMEB_02012 3.9e-82 K WHG domain
EFMJKMEB_02013 3.2e-91 V abc transporter atp-binding protein
EFMJKMEB_02014 5.9e-23 P FtsX-like permease family
EFMJKMEB_02015 2.4e-40 S Sugar efflux transporter for intercellular exchange
EFMJKMEB_02016 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
EFMJKMEB_02017 8.1e-161 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
EFMJKMEB_02018 2.4e-161 ET ABC transporter substrate-binding protein
EFMJKMEB_02019 6.1e-107 ytmL P ABC transporter (Permease
EFMJKMEB_02020 3e-114 yxeN P ABC transporter, permease protein
EFMJKMEB_02021 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
EFMJKMEB_02025 3.2e-92 dps P Belongs to the Dps family
EFMJKMEB_02026 4.4e-79 perR P Belongs to the Fur family
EFMJKMEB_02027 1.9e-27 yqgQ S protein conserved in bacteria
EFMJKMEB_02028 7.8e-177 glk 2.7.1.2 G Glucokinase
EFMJKMEB_02029 0.0 typA T GTP-binding protein TypA
EFMJKMEB_02031 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EFMJKMEB_02032 3.9e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EFMJKMEB_02033 8.2e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EFMJKMEB_02034 1.2e-250 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EFMJKMEB_02035 2.7e-236 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EFMJKMEB_02036 5.1e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EFMJKMEB_02037 1.4e-96 sepF D cell septum assembly
EFMJKMEB_02038 9.7e-34 yggT D integral membrane protein
EFMJKMEB_02039 8e-143 ylmH T S4 RNA-binding domain
EFMJKMEB_02040 9.7e-134 divIVA D Cell division protein DivIVA
EFMJKMEB_02041 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EFMJKMEB_02042 7.9e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
EFMJKMEB_02043 4.1e-242 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
EFMJKMEB_02044 2e-45 rpmE2 J 50S ribosomal protein L31
EFMJKMEB_02045 1.2e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EFMJKMEB_02046 7.6e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
EFMJKMEB_02047 2.6e-154 gst O Glutathione S-transferase
EFMJKMEB_02048 6.7e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EFMJKMEB_02049 3.5e-111 tdk 2.7.1.21 F thymidine kinase
EFMJKMEB_02050 1.8e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EFMJKMEB_02051 6.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EFMJKMEB_02052 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EFMJKMEB_02053 3.4e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EFMJKMEB_02054 1.3e-174 ndpA S 37-kD nucleoid-associated bacterial protein
EFMJKMEB_02055 8e-100 pvaA M lytic transglycosylase activity
EFMJKMEB_02056 6.5e-307 yfiB1 V abc transporter atp-binding protein
EFMJKMEB_02057 9.7e-311 XK27_10035 V abc transporter atp-binding protein
EFMJKMEB_02058 1.3e-09 S D-Ala-teichoic acid biosynthesis protein
EFMJKMEB_02059 6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFMJKMEB_02060 1.6e-235 dltB M Membrane protein involved in D-alanine export
EFMJKMEB_02061 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFMJKMEB_02062 4.4e-228 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EFMJKMEB_02063 4.9e-57 L Integrase core domain protein
EFMJKMEB_02064 3.7e-18 L transposase activity
EFMJKMEB_02065 3.6e-39 L Transposase
EFMJKMEB_02066 0.0 3.6.3.8 P cation transport ATPase
EFMJKMEB_02067 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
EFMJKMEB_02069 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EFMJKMEB_02070 2.1e-165 metF 1.5.1.20 C reductase
EFMJKMEB_02071 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EFMJKMEB_02072 1.1e-93 panT S ECF transporter, substrate-specific component
EFMJKMEB_02073 2.8e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EFMJKMEB_02074 2.8e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
EFMJKMEB_02075 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EFMJKMEB_02076 1.2e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFMJKMEB_02077 4.1e-43 T PhoQ Sensor
EFMJKMEB_02078 1.7e-120 T PhoQ Sensor

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)