ORF_ID e_value Gene_name EC_number CAZy COGs Description
GHKNIELH_00001 8.9e-99 K Transcriptional regulator C-terminal region
GHKNIELH_00002 3.6e-197 S membrane
GHKNIELH_00003 2.1e-117 GM NAD(P)H-binding
GHKNIELH_00004 5.3e-127 cobB K Sir2 family
GHKNIELH_00005 7.5e-183 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHKNIELH_00006 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
GHKNIELH_00007 5e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GHKNIELH_00008 6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GHKNIELH_00009 4.8e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHKNIELH_00010 9.8e-163 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHKNIELH_00011 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHKNIELH_00012 1e-20 rplQ J Ribosomal protein L17
GHKNIELH_00013 2.8e-24 rplQ J Ribosomal protein L17
GHKNIELH_00014 2.9e-36 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHKNIELH_00015 6.4e-86 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHKNIELH_00016 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GHKNIELH_00017 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GHKNIELH_00018 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GHKNIELH_00019 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GHKNIELH_00020 6.5e-50 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GHKNIELH_00021 5.4e-53 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GHKNIELH_00022 4.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GHKNIELH_00023 1.3e-70 rplO J Binds to the 23S rRNA
GHKNIELH_00024 1.4e-23 rpmD J Ribosomal protein L30
GHKNIELH_00025 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GHKNIELH_00026 1.5e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GHKNIELH_00027 2.9e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GHKNIELH_00028 2.1e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GHKNIELH_00029 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GHKNIELH_00030 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GHKNIELH_00031 1.1e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GHKNIELH_00032 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GHKNIELH_00033 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GHKNIELH_00034 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
GHKNIELH_00035 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GHKNIELH_00036 1.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GHKNIELH_00037 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GHKNIELH_00038 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GHKNIELH_00039 1.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GHKNIELH_00040 1.7e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GHKNIELH_00041 1e-105 rplD J Forms part of the polypeptide exit tunnel
GHKNIELH_00042 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GHKNIELH_00043 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
GHKNIELH_00044 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GHKNIELH_00045 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GHKNIELH_00046 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GHKNIELH_00047 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHKNIELH_00048 1.9e-186 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHKNIELH_00049 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHKNIELH_00050 3.6e-177 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GHKNIELH_00051 2.9e-46 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GHKNIELH_00052 1.9e-116 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GHKNIELH_00053 3.8e-42 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GHKNIELH_00055 1.6e-08
GHKNIELH_00056 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GHKNIELH_00057 3.4e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GHKNIELH_00058 2.7e-160 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GHKNIELH_00059 0.0 S membrane
GHKNIELH_00060 0.0 S membrane
GHKNIELH_00061 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GHKNIELH_00062 1.1e-242 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GHKNIELH_00063 7.1e-59 yabR J S1 RNA binding domain
GHKNIELH_00064 4e-60 divIC D Septum formation initiator
GHKNIELH_00065 5.4e-34 yabO J S4 domain protein
GHKNIELH_00066 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GHKNIELH_00067 4.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GHKNIELH_00068 3.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GHKNIELH_00069 1.3e-122 S (CBS) domain
GHKNIELH_00070 1.3e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GHKNIELH_00071 5.9e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GHKNIELH_00072 2.7e-180 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GHKNIELH_00073 9.8e-68 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GHKNIELH_00074 7e-234 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GHKNIELH_00075 8e-41 rpmE2 J Ribosomal protein L31
GHKNIELH_00076 3.9e-298 ybeC E amino acid
GHKNIELH_00077 2.6e-135 XK27_08845 S ABC transporter, ATP-binding protein
GHKNIELH_00078 3.5e-139 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
GHKNIELH_00079 2.1e-177 ABC-SBP S ABC transporter
GHKNIELH_00080 3.3e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GHKNIELH_00081 5.3e-283 pipD E Dipeptidase
GHKNIELH_00082 2.4e-141 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GHKNIELH_00083 1.4e-78 XK27_02070 S Nitroreductase family
GHKNIELH_00084 1.1e-31 hxlR K Transcriptional regulator, HxlR family
GHKNIELH_00085 2.1e-79
GHKNIELH_00086 3.7e-67 S Putative adhesin
GHKNIELH_00087 1.6e-39
GHKNIELH_00088 1.2e-190 yfdV S Membrane transport protein
GHKNIELH_00089 1e-36 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GHKNIELH_00090 4.3e-272 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GHKNIELH_00091 4.1e-264 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GHKNIELH_00092 1.3e-38
GHKNIELH_00093 8.9e-204 ywhK S Membrane
GHKNIELH_00094 3.9e-39
GHKNIELH_00096 1.9e-291 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GHKNIELH_00097 6.1e-235 dltB M MBOAT, membrane-bound O-acyltransferase family
GHKNIELH_00098 6.7e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GHKNIELH_00099 3.4e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GHKNIELH_00100 1.2e-146 pbpX2 V Beta-lactamase
GHKNIELH_00101 2.8e-216 lmrP E Major Facilitator Superfamily
GHKNIELH_00102 5.4e-39
GHKNIELH_00103 1.6e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHKNIELH_00104 5.4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
GHKNIELH_00105 0.0 clpE2 O AAA domain (Cdc48 subfamily)
GHKNIELH_00106 1.8e-251 yfnA E Amino Acid
GHKNIELH_00109 1.1e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GHKNIELH_00110 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GHKNIELH_00111 9.4e-158 asp3 S Accessory Sec secretory system ASP3
GHKNIELH_00112 6.6e-303 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
GHKNIELH_00113 4.3e-59 asp1 S Accessory Sec system protein Asp1
GHKNIELH_00114 2.1e-123 asp1 S Accessory Sec system protein Asp1
GHKNIELH_00115 3.9e-45 asp1 S Accessory Sec system protein Asp1
GHKNIELH_00116 1.3e-213 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
GHKNIELH_00117 8.9e-306 gadC E Contains amino acid permease domain
GHKNIELH_00118 1.4e-70 UW LPXTG-motif cell wall anchor domain protein
GHKNIELH_00119 1.9e-126 UW LPXTG-motif cell wall anchor domain protein
GHKNIELH_00120 0.0 UW LPXTG-motif cell wall anchor domain protein
GHKNIELH_00121 1.1e-51 UW LPXTG-motif cell wall anchor domain protein
GHKNIELH_00122 7.5e-185 S AAA domain
GHKNIELH_00123 4.1e-124 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GHKNIELH_00124 9.9e-12
GHKNIELH_00125 5.3e-40
GHKNIELH_00126 2.8e-31 czcD P cation diffusion facilitator family transporter
GHKNIELH_00127 2.2e-106 czcD P cation diffusion facilitator family transporter
GHKNIELH_00128 1.6e-52 K Transcriptional regulator, ArsR family
GHKNIELH_00129 6.2e-128 pgm3 G Belongs to the phosphoglycerate mutase family
GHKNIELH_00130 1.4e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
GHKNIELH_00131 4.6e-152 1.6.5.2 GM NmrA-like family
GHKNIELH_00132 3.5e-68 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
GHKNIELH_00133 4.5e-283 V ABC-type multidrug transport system, ATPase and permease components
GHKNIELH_00134 1.1e-255 P ABC transporter
GHKNIELH_00135 6e-104 ropB K Transcriptional regulator
GHKNIELH_00136 9.5e-87 V ABC-type multidrug transport system, ATPase and permease components
GHKNIELH_00137 5.4e-237 clcA P chloride
GHKNIELH_00138 0.0 tetP J elongation factor G
GHKNIELH_00139 8.1e-143 ropB K Helix-turn-helix domain
GHKNIELH_00140 9.6e-289 V ABC-type multidrug transport system, ATPase and permease components
GHKNIELH_00141 3.5e-17
GHKNIELH_00142 1.1e-153 yitS S EDD domain protein, DegV family
GHKNIELH_00143 2.9e-136 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GHKNIELH_00144 1.8e-127 S Protein of unknown function (DUF975)
GHKNIELH_00145 3.3e-115 ywnB S NAD(P)H-binding
GHKNIELH_00146 9.7e-163 arbZ I Acyltransferase
GHKNIELH_00147 3.3e-214 S Sterol carrier protein domain
GHKNIELH_00149 3.1e-248 steT E amino acid
GHKNIELH_00150 2.7e-76 L Belongs to the 'phage' integrase family
GHKNIELH_00151 3.6e-129 L Belongs to the 'phage' integrase family
GHKNIELH_00152 1.5e-31
GHKNIELH_00153 4.6e-108 repB EP Plasmid replication protein
GHKNIELH_00154 1.4e-62 repB EP Plasmid replication protein
GHKNIELH_00155 7e-46
GHKNIELH_00156 1.2e-143 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GHKNIELH_00157 4.6e-54
GHKNIELH_00158 1.6e-182
GHKNIELH_00159 2.7e-58 cadX K Bacterial regulatory protein, arsR family
GHKNIELH_00160 3.3e-96 cadD P Cadmium resistance transporter
GHKNIELH_00162 0.0
GHKNIELH_00163 8.2e-218 I Protein of unknown function (DUF2974)
GHKNIELH_00165 1.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
GHKNIELH_00166 1.6e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GHKNIELH_00167 4.8e-76 rplI J Binds to the 23S rRNA
GHKNIELH_00168 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GHKNIELH_00169 3.5e-158 corA P CorA-like Mg2+ transporter protein
GHKNIELH_00170 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GHKNIELH_00171 7.3e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GHKNIELH_00172 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
GHKNIELH_00173 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHKNIELH_00174 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHKNIELH_00175 1.2e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GHKNIELH_00176 1.6e-20 yaaA S S4 domain
GHKNIELH_00177 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GHKNIELH_00178 2.4e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GHKNIELH_00179 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GHKNIELH_00180 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GHKNIELH_00181 1.6e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GHKNIELH_00182 1.9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GHKNIELH_00183 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GHKNIELH_00184 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GHKNIELH_00185 1e-270 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GHKNIELH_00186 2.7e-288 clcA P chloride
GHKNIELH_00187 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GHKNIELH_00188 3.2e-11 S RelB antitoxin
GHKNIELH_00189 7.5e-162 add 3.5.4.2, 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GHKNIELH_00190 1.5e-210 pbuG S permease
GHKNIELH_00191 6.5e-286 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GHKNIELH_00192 3.8e-69 S Iron-sulphur cluster biosynthesis
GHKNIELH_00193 1.9e-242 EGP Sugar (and other) transporter
GHKNIELH_00194 2.7e-70 K Acetyltransferase (GNAT) domain
GHKNIELH_00195 3.2e-247 ynbB 4.4.1.1 P aluminum resistance
GHKNIELH_00196 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
GHKNIELH_00197 4e-281 E Amino acid permease
GHKNIELH_00198 8e-160 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GHKNIELH_00199 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
GHKNIELH_00201 1.9e-35 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHKNIELH_00202 4.7e-40
GHKNIELH_00203 8.8e-118 3.1.3.48 T Tyrosine phosphatase family
GHKNIELH_00204 3.8e-60
GHKNIELH_00205 1.4e-47 S MazG-like family
GHKNIELH_00207 6.1e-35 FG HIT domain
GHKNIELH_00208 4e-42
GHKNIELH_00210 1.2e-74 K Acetyltransferase (GNAT) domain
GHKNIELH_00211 4.6e-43
GHKNIELH_00212 3.4e-63
GHKNIELH_00213 4.3e-15
GHKNIELH_00214 8.4e-54
GHKNIELH_00215 1.7e-277 V ABC transporter transmembrane region
GHKNIELH_00216 2.1e-28 C nitroreductase
GHKNIELH_00217 3.1e-31 C nitroreductase
GHKNIELH_00218 8.3e-205 yhjX P Major Facilitator Superfamily
GHKNIELH_00219 5.8e-177 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHKNIELH_00220 2.4e-41 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHKNIELH_00221 3e-64
GHKNIELH_00222 3.6e-73 V ABC-type multidrug transport system, ATPase and permease components
GHKNIELH_00223 2.6e-175 V ABC-type multidrug transport system, ATPase and permease components
GHKNIELH_00224 1.9e-94 P ABC transporter
GHKNIELH_00225 4e-109 V (ABC) transporter
GHKNIELH_00226 3.5e-68 qmcA O prohibitin homologues
GHKNIELH_00227 1.8e-44 qmcA O prohibitin homologues
GHKNIELH_00228 9.1e-51 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
GHKNIELH_00229 7.5e-40 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GHKNIELH_00230 3.7e-41 K sequence-specific DNA binding
GHKNIELH_00231 1.8e-122 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GHKNIELH_00233 6.3e-47 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GHKNIELH_00234 5.3e-45 S SnoaL-like domain
GHKNIELH_00235 2e-163 C Oxidoreductase
GHKNIELH_00236 6e-117 drgA C nitroreductase
GHKNIELH_00237 3.1e-305 2.7.7.7 S Domain of unknown function (DUF5060)
GHKNIELH_00238 4.2e-167 uhpT EGP Major facilitator Superfamily
GHKNIELH_00239 2.7e-169 rbsR K helix_turn _helix lactose operon repressor
GHKNIELH_00240 1.2e-205 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GHKNIELH_00241 3.5e-35 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GHKNIELH_00242 4.3e-65 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GHKNIELH_00243 4.9e-151 licT K CAT RNA binding domain
GHKNIELH_00244 4.2e-129 G Protein of unknown function (DUF4038)
GHKNIELH_00245 7.1e-103 G Protein of unknown function (DUF4038)
GHKNIELH_00246 7.9e-290 G isomerase
GHKNIELH_00247 1.7e-72 purR13 K Bacterial regulatory proteins, lacI family
GHKNIELH_00248 1.9e-93 purR13 K Bacterial regulatory proteins, lacI family
GHKNIELH_00249 8.8e-153 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
GHKNIELH_00250 1.9e-175 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
GHKNIELH_00251 3.7e-263 glpK_1 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GHKNIELH_00252 1.8e-98 pepO 3.4.24.71 O Peptidase family M13
GHKNIELH_00253 1.2e-94 pepO 3.4.24.71 O Peptidase family M13
GHKNIELH_00254 1.7e-118 pepO 3.4.24.71 O Peptidase family M13
GHKNIELH_00255 2.1e-31 XK27_06780 V ABC transporter permease
GHKNIELH_00256 2.6e-68 XK27_06780 V ABC transporter permease
GHKNIELH_00257 1.5e-29 XK27_06780 V ABC transporter permease
GHKNIELH_00258 2.2e-45 XK27_06780 V ABC transporter permease
GHKNIELH_00259 2.1e-81 XK27_06780 V ABC transporter permease
GHKNIELH_00260 5.1e-79 XK27_06785 V ABC transporter, ATP-binding protein
GHKNIELH_00261 4.5e-107 alkD L DNA alkylation repair enzyme
GHKNIELH_00262 3.5e-205 M Glycosyl transferases group 1
GHKNIELH_00263 1.5e-101 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GHKNIELH_00264 9.9e-209 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GHKNIELH_00265 2.2e-122 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GHKNIELH_00266 7.2e-41 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GHKNIELH_00267 5.9e-105 pncA Q Isochorismatase family
GHKNIELH_00268 3.1e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GHKNIELH_00269 6.6e-68 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GHKNIELH_00270 1.5e-124 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GHKNIELH_00271 1.1e-217 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GHKNIELH_00272 5.9e-36 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GHKNIELH_00273 2.8e-86 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GHKNIELH_00274 2.4e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GHKNIELH_00275 4.4e-141 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GHKNIELH_00276 7e-56 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GHKNIELH_00277 1.1e-60 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GHKNIELH_00278 7.2e-53 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GHKNIELH_00279 1.1e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GHKNIELH_00280 1.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GHKNIELH_00281 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GHKNIELH_00282 4.8e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GHKNIELH_00283 1.4e-300 I Protein of unknown function (DUF2974)
GHKNIELH_00284 8.9e-150 yxeH S hydrolase
GHKNIELH_00285 2.5e-104 XK27_05540 S DUF218 domain
GHKNIELH_00286 3.4e-35 XK27_05540 S DUF218 domain
GHKNIELH_00287 6.1e-49 ybjQ S Belongs to the UPF0145 family
GHKNIELH_00288 1.3e-55 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
GHKNIELH_00289 6.5e-102 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
GHKNIELH_00290 3.5e-107
GHKNIELH_00291 3.5e-23
GHKNIELH_00292 3.8e-13
GHKNIELH_00293 9.8e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GHKNIELH_00294 4.7e-22
GHKNIELH_00295 6e-127
GHKNIELH_00296 2.2e-117
GHKNIELH_00297 4.7e-123 skfE V ATPases associated with a variety of cellular activities
GHKNIELH_00298 3.6e-58 yvoA_1 K Transcriptional regulator, GntR family
GHKNIELH_00299 1.1e-211 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GHKNIELH_00300 1.1e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GHKNIELH_00301 8.7e-82 trmK 2.1.1.217 S SAM-dependent methyltransferase
GHKNIELH_00302 6.5e-143 cjaA ET ABC transporter substrate-binding protein
GHKNIELH_00303 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GHKNIELH_00304 8.6e-106 P ABC transporter permease
GHKNIELH_00305 1.7e-67 papP P ABC transporter, permease protein
GHKNIELH_00306 2.3e-34 papP P ABC transporter, permease protein
GHKNIELH_00307 1.8e-153 S DNA/RNA non-specific endonuclease
GHKNIELH_00308 1.9e-145 M domain protein
GHKNIELH_00310 9.1e-72
GHKNIELH_00311 4.4e-38
GHKNIELH_00312 7.2e-18
GHKNIELH_00314 1.3e-117 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GHKNIELH_00315 4e-38 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GHKNIELH_00316 3.5e-18 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GHKNIELH_00317 5.1e-93 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GHKNIELH_00318 1.5e-115 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GHKNIELH_00319 7e-66 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GHKNIELH_00320 1.1e-55 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GHKNIELH_00321 1e-221 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GHKNIELH_00322 2.7e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GHKNIELH_00323 5.2e-136 recO L Involved in DNA repair and RecF pathway recombination
GHKNIELH_00324 9.6e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GHKNIELH_00325 1.6e-21 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GHKNIELH_00326 1.1e-27 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GHKNIELH_00327 1.8e-14 phoH T phosphate starvation-inducible protein PhoH
GHKNIELH_00328 2.4e-113 phoH T phosphate starvation-inducible protein PhoH
GHKNIELH_00329 2.9e-33 yqeY S YqeY-like protein
GHKNIELH_00330 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GHKNIELH_00331 2.5e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GHKNIELH_00332 4.1e-50 S Iron-sulfur cluster assembly protein
GHKNIELH_00333 2.4e-58 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GHKNIELH_00334 8.5e-65 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GHKNIELH_00335 4.5e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GHKNIELH_00336 3.1e-86 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GHKNIELH_00337 5.2e-47 E GDSL-like Lipase/Acylhydrolase family
GHKNIELH_00338 5.2e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GHKNIELH_00339 5.1e-139 patA 2.6.1.1 E Aminotransferase
GHKNIELH_00340 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GHKNIELH_00341 6.2e-246 hisS 6.1.1.21 J histidyl-tRNA synthetase
GHKNIELH_00342 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GHKNIELH_00343 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GHKNIELH_00344 2.4e-65
GHKNIELH_00345 2.7e-123 prmA J Ribosomal protein L11 methyltransferase
GHKNIELH_00346 5.3e-68 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GHKNIELH_00347 2.6e-289 S Bacterial membrane protein, YfhO
GHKNIELH_00348 4.6e-183 S Bacterial membrane protein, YfhO
GHKNIELH_00349 3.5e-109 S Bacterial membrane protein, YfhO
GHKNIELH_00350 0.0 aha1 P E1-E2 ATPase
GHKNIELH_00351 2.9e-190 ansA 3.5.1.1 EJ L-asparaginase, type I
GHKNIELH_00352 1.8e-19 yjjP S Putative threonine/serine exporter
GHKNIELH_00353 7e-193 yjjP S Putative threonine/serine exporter
GHKNIELH_00354 9.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GHKNIELH_00355 9.8e-258 frdC 1.3.5.4 C FAD binding domain
GHKNIELH_00356 1.2e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GHKNIELH_00357 5.9e-50 metI P ABC transporter permease
GHKNIELH_00358 9.1e-12 metI P ABC-type metal ion transport system, permease component
GHKNIELH_00359 2.9e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GHKNIELH_00360 1.5e-155 metQ1 P Belongs to the nlpA lipoprotein family
GHKNIELH_00361 1.1e-30 L nuclease
GHKNIELH_00362 2.1e-18 F DNA/RNA non-specific endonuclease
GHKNIELH_00363 2.9e-41 F DNA/RNA non-specific endonuclease
GHKNIELH_00364 3.8e-48 K Helix-turn-helix domain
GHKNIELH_00365 1.2e-41 L Helix-turn-helix domain
GHKNIELH_00366 5.2e-87 L PFAM Integrase catalytic region
GHKNIELH_00367 3.3e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GHKNIELH_00368 1.5e-305 ybiT S ABC transporter, ATP-binding protein
GHKNIELH_00369 3.7e-18 S Sugar efflux transporter for intercellular exchange
GHKNIELH_00370 4.2e-43 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHKNIELH_00371 9.2e-71 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHKNIELH_00372 3.6e-89 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHKNIELH_00373 2.2e-102 3.6.1.27 I Acid phosphatase homologues
GHKNIELH_00375 4.3e-155 lysR5 K LysR substrate binding domain
GHKNIELH_00376 1.3e-94 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
GHKNIELH_00377 2.3e-206 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
GHKNIELH_00378 1.6e-35 G Major Facilitator
GHKNIELH_00379 3.5e-205 G Major Facilitator
GHKNIELH_00380 9.7e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GHKNIELH_00381 1.5e-67 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GHKNIELH_00382 9.9e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHKNIELH_00383 1.9e-26 yjeM E Amino Acid
GHKNIELH_00384 6.1e-77 yjeM E Amino Acid
GHKNIELH_00385 1.2e-152 yjeM E Amino Acid
GHKNIELH_00386 4.8e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GHKNIELH_00387 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
GHKNIELH_00388 7.1e-124 srtA 3.4.22.70 M sortase family
GHKNIELH_00389 1.4e-59 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GHKNIELH_00390 4.9e-279 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GHKNIELH_00391 5.7e-174 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GHKNIELH_00392 0.0 dnaK O Heat shock 70 kDa protein
GHKNIELH_00393 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GHKNIELH_00394 1.3e-176 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GHKNIELH_00395 1.6e-90 S GyrI-like small molecule binding domain
GHKNIELH_00396 2.7e-21 lsa S ABC transporter
GHKNIELH_00397 1.6e-219 lsa S ABC transporter
GHKNIELH_00398 1.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GHKNIELH_00399 2.3e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GHKNIELH_00400 6e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GHKNIELH_00401 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GHKNIELH_00402 1.6e-41 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GHKNIELH_00403 1.6e-29 ylxR K Protein of unknown function (DUF448)
GHKNIELH_00404 1.4e-218 nusA K Participates in both transcription termination and antitermination
GHKNIELH_00405 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
GHKNIELH_00406 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GHKNIELH_00407 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GHKNIELH_00408 9.3e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GHKNIELH_00409 9.9e-71 cdsA 2.7.7.41 S Belongs to the CDS family
GHKNIELH_00410 2.2e-48 cdsA 2.7.7.41 S Belongs to the CDS family
GHKNIELH_00411 8.5e-136 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GHKNIELH_00412 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GHKNIELH_00413 5.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GHKNIELH_00414 9.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GHKNIELH_00415 5.8e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
GHKNIELH_00416 2.6e-183 yabB 2.1.1.223 L Methyltransferase small domain
GHKNIELH_00417 2.6e-117 plsC 2.3.1.51 I Acyltransferase
GHKNIELH_00418 1.5e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
GHKNIELH_00419 6.6e-12 L COG2826 Transposase and inactivated derivatives, IS30 family
GHKNIELH_00420 1.9e-53 L COG2826 Transposase and inactivated derivatives, IS30 family
GHKNIELH_00424 3.2e-20 S Bacteriocin class II with double-glycine leader peptide
GHKNIELH_00425 4.9e-105 M Transport protein ComB
GHKNIELH_00426 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GHKNIELH_00427 6e-32 K LytTr DNA-binding domain
GHKNIELH_00428 4.6e-225 2.7.13.3 T GHKL domain
GHKNIELH_00430 8.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
GHKNIELH_00432 6.4e-76 S Putative adhesin
GHKNIELH_00433 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GHKNIELH_00434 1.1e-130 treR K UTRA
GHKNIELH_00435 3.9e-24 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
GHKNIELH_00436 9.2e-283 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
GHKNIELH_00437 1.9e-65
GHKNIELH_00438 5.7e-107 glnP P ABC transporter permease
GHKNIELH_00439 1.3e-88 gluC P ABC transporter permease
GHKNIELH_00440 3.1e-150 glnH ET ABC transporter
GHKNIELH_00441 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GHKNIELH_00442 3.8e-148 glnH ET ABC transporter
GHKNIELH_00443 0.0 V ABC transporter transmembrane region
GHKNIELH_00444 8.1e-236 XK27_09600 V ABC transporter, ATP-binding protein
GHKNIELH_00445 9.4e-34 XK27_09600 V ABC transporter, ATP-binding protein
GHKNIELH_00446 8.7e-67 K Transcriptional regulator, MarR family
GHKNIELH_00447 2.8e-154 S Alpha beta hydrolase
GHKNIELH_00448 1.5e-217 naiP EGP Major facilitator Superfamily
GHKNIELH_00449 1.6e-279 pipD E Peptidase family C69
GHKNIELH_00450 4.3e-283 dtpT U amino acid peptide transporter
GHKNIELH_00451 1e-28 lacA 3.2.1.23 G -beta-galactosidase
GHKNIELH_00452 5.4e-291 lacA 3.2.1.23 G -beta-galactosidase
GHKNIELH_00453 0.0 yic1 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
GHKNIELH_00454 5.4e-302 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GHKNIELH_00455 3.1e-74 bglK 2.7.1.2, 2.7.1.85 GK ROK family
GHKNIELH_00456 1.3e-71 bglK 2.7.1.2, 2.7.1.85 GK ROK family
GHKNIELH_00457 2.8e-205 xylR GK ROK family
GHKNIELH_00458 2.3e-240 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHKNIELH_00459 3.6e-254 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
GHKNIELH_00460 4.9e-268 aaxC E Arginine ornithine antiporter
GHKNIELH_00461 9.8e-260 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
GHKNIELH_00462 2.3e-20 ybbM S Uncharacterised protein family (UPF0014)
GHKNIELH_00463 2.4e-99 ybbM S Uncharacterised protein family (UPF0014)
GHKNIELH_00464 5.9e-112 ybbL S ABC transporter, ATP-binding protein
GHKNIELH_00466 2.1e-207 pepA E M42 glutamyl aminopeptidase
GHKNIELH_00467 9.4e-77
GHKNIELH_00468 1.1e-66 K helix_turn_helix multiple antibiotic resistance protein
GHKNIELH_00469 3.1e-31
GHKNIELH_00470 4.3e-217 mdtG EGP Major facilitator Superfamily
GHKNIELH_00471 2.4e-69 yagE E amino acid
GHKNIELH_00472 2.3e-171 yagE E amino acid
GHKNIELH_00473 8.6e-309 gadC E Contains amino acid permease domain
GHKNIELH_00474 1.2e-263 pepC 3.4.22.40 E Peptidase C1-like family
GHKNIELH_00475 6.3e-276 pipD E Peptidase family C69
GHKNIELH_00476 9.1e-282 gadC E Contains amino acid permease domain
GHKNIELH_00477 1.2e-265 pepC 3.4.22.40 E Peptidase C1-like family
GHKNIELH_00478 4.6e-284 E Phospholipase B
GHKNIELH_00479 2.8e-111 3.6.1.27 I Acid phosphatase homologues
GHKNIELH_00480 1.4e-141 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHKNIELH_00481 4.3e-176 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GHKNIELH_00482 3e-74 K Helix-turn-helix domain, rpiR family
GHKNIELH_00483 3.3e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
GHKNIELH_00484 8.7e-223 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
GHKNIELH_00485 5.7e-32 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
GHKNIELH_00486 5e-299 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
GHKNIELH_00487 4e-54 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
GHKNIELH_00488 4.3e-131 lacT K CAT RNA binding domain
GHKNIELH_00489 4.7e-105 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
GHKNIELH_00490 5.1e-72 lacA 5.3.1.26 G Ribose/Galactose Isomerase
GHKNIELH_00491 6e-132 lacR K DeoR C terminal sensor domain
GHKNIELH_00492 5.6e-242 pyrP F Permease
GHKNIELH_00493 3.6e-154 K Transcriptional regulator
GHKNIELH_00494 9.2e-147 S hydrolase
GHKNIELH_00495 1.3e-101 yagU S Protein of unknown function (DUF1440)
GHKNIELH_00496 8.4e-145 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GHKNIELH_00497 1.1e-209 L Putative transposase DNA-binding domain
GHKNIELH_00498 3.4e-76 2.3.1.128 K acetyltransferase
GHKNIELH_00499 4.8e-160 emrY EGP Major facilitator Superfamily
GHKNIELH_00500 8.5e-67 emrY EGP Major facilitator Superfamily
GHKNIELH_00501 1.3e-252 emrY EGP Major facilitator Superfamily
GHKNIELH_00502 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GHKNIELH_00503 2.4e-136 S CAAX amino terminal protease
GHKNIELH_00504 1.1e-162 mleP3 S Membrane transport protein
GHKNIELH_00505 7e-101 tag 3.2.2.20 L glycosylase
GHKNIELH_00506 8e-193 S Bacteriocin helveticin-J
GHKNIELH_00507 3.8e-128 yfeO P Voltage gated chloride channel
GHKNIELH_00508 4.6e-29 yfeO P Voltage gated chloride channel
GHKNIELH_00509 3.8e-81 yebR 1.8.4.14 T GAF domain-containing protein
GHKNIELH_00510 1.7e-84 tlpA2 L Transposase IS200 like
GHKNIELH_00511 3.5e-252 L transposase, IS605 OrfB family
GHKNIELH_00512 4.9e-111 ylbE GM NAD(P)H-binding
GHKNIELH_00513 4.4e-126 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
GHKNIELH_00514 1.6e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GHKNIELH_00516 2.7e-46
GHKNIELH_00517 1.8e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
GHKNIELH_00518 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GHKNIELH_00519 3e-170 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GHKNIELH_00520 1e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GHKNIELH_00521 8.8e-136
GHKNIELH_00522 1.5e-216 MA20_36090 S Protein of unknown function (DUF2974)
GHKNIELH_00523 3.6e-266 ytgP S Polysaccharide biosynthesis protein
GHKNIELH_00524 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHKNIELH_00525 6.8e-116 3.6.1.27 I Acid phosphatase homologues
GHKNIELH_00526 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GHKNIELH_00527 1.3e-182 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GHKNIELH_00528 3.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
GHKNIELH_00529 9.9e-219 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
GHKNIELH_00541 3.4e-61
GHKNIELH_00547 3.9e-257 qacA EGP Major facilitator Superfamily
GHKNIELH_00548 1.7e-151 2.7.13.3 T GHKL domain
GHKNIELH_00549 3.6e-39
GHKNIELH_00550 5.7e-31
GHKNIELH_00551 3.4e-74 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
GHKNIELH_00552 6.1e-137 L oxidized base lesion DNA N-glycosylase activity
GHKNIELH_00553 6.4e-243 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GHKNIELH_00554 5.4e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GHKNIELH_00555 2.4e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GHKNIELH_00556 3.4e-92 clcA P chloride
GHKNIELH_00557 1e-108 clcA P chloride
GHKNIELH_00558 7.2e-115
GHKNIELH_00559 1e-146
GHKNIELH_00560 8.7e-174 D nuclear chromosome segregation
GHKNIELH_00561 9e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GHKNIELH_00562 1.1e-95 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
GHKNIELH_00563 1e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
GHKNIELH_00564 1.4e-84 folT S ECF transporter, substrate-specific component
GHKNIELH_00565 4.9e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
GHKNIELH_00566 3.7e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GHKNIELH_00567 4.4e-58 yabA L Involved in initiation control of chromosome replication
GHKNIELH_00568 3.1e-153 holB 2.7.7.7 L DNA polymerase III
GHKNIELH_00569 5e-51 yaaQ S Cyclic-di-AMP receptor
GHKNIELH_00570 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GHKNIELH_00571 9e-26 S Protein of unknown function (DUF2508)
GHKNIELH_00572 8.1e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GHKNIELH_00573 1.7e-51 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GHKNIELH_00574 7.5e-166 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GHKNIELH_00575 1.5e-112 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GHKNIELH_00576 1e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GHKNIELH_00577 1.5e-39 S Protein conserved in bacteria
GHKNIELH_00578 9e-145
GHKNIELH_00579 3.9e-21
GHKNIELH_00580 1.5e-112 rsmC 2.1.1.172 J Methyltransferase
GHKNIELH_00581 2.7e-32
GHKNIELH_00582 7.2e-129 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
GHKNIELH_00583 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GHKNIELH_00584 4.2e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GHKNIELH_00585 2.2e-145 aatB ET ABC transporter substrate-binding protein
GHKNIELH_00586 9.3e-43 glnQ 3.6.3.21 E ABC transporter
GHKNIELH_00587 5.2e-21 glnQ 3.6.3.21 E ABC transporter
GHKNIELH_00588 7.9e-109 glnP P ABC transporter permease
GHKNIELH_00589 3.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GHKNIELH_00590 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GHKNIELH_00591 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
GHKNIELH_00592 3.4e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GHKNIELH_00593 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GHKNIELH_00594 2.5e-189 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GHKNIELH_00595 1.3e-227 G Major Facilitator Superfamily
GHKNIELH_00596 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GHKNIELH_00597 2.6e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
GHKNIELH_00598 1.7e-34
GHKNIELH_00599 1e-88 yvrI K sigma factor activity
GHKNIELH_00600 2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHKNIELH_00601 1.3e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GHKNIELH_00602 1.2e-151 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHKNIELH_00603 1.2e-112 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHKNIELH_00604 1.5e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GHKNIELH_00605 1.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GHKNIELH_00606 6.5e-09 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
GHKNIELH_00607 1.2e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
GHKNIELH_00608 1.2e-186 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GHKNIELH_00609 8.1e-265 pepC 3.4.22.40 E Peptidase C1-like family
GHKNIELH_00610 8.4e-150 mdlB V ABC transporter
GHKNIELH_00611 2.6e-133 mdlB V ABC transporter
GHKNIELH_00612 0.0 mdlA V ABC transporter
GHKNIELH_00613 3.3e-30 yneF S Uncharacterised protein family (UPF0154)
GHKNIELH_00614 2.4e-13 ynzC S UPF0291 protein
GHKNIELH_00615 1.6e-22 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GHKNIELH_00616 2e-42 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GHKNIELH_00617 3.6e-35 ung2 3.2.2.27 L Uracil-DNA glycosylase
GHKNIELH_00618 8.4e-38 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
GHKNIELH_00619 1.3e-09 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
GHKNIELH_00620 8.9e-76 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GHKNIELH_00621 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GHKNIELH_00622 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GHKNIELH_00623 3.1e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GHKNIELH_00624 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GHKNIELH_00625 4.4e-78 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GHKNIELH_00626 1e-33 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GHKNIELH_00627 1.2e-15 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GHKNIELH_00628 3.6e-21 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GHKNIELH_00629 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GHKNIELH_00630 7.5e-285 pipD E Dipeptidase
GHKNIELH_00631 8.9e-105 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GHKNIELH_00632 3.9e-07 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GHKNIELH_00633 0.0 smc D Required for chromosome condensation and partitioning
GHKNIELH_00634 1.9e-77 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GHKNIELH_00635 2.3e-13 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GHKNIELH_00636 0.0 oppA E ABC transporter substrate-binding protein
GHKNIELH_00637 0.0 oppA E ABC transporter substrate-binding protein
GHKNIELH_00638 9.3e-29 oppC P Binding-protein-dependent transport system inner membrane component
GHKNIELH_00639 4.7e-124 oppC P Binding-protein-dependent transport system inner membrane component
GHKNIELH_00640 1.6e-177 oppB P ABC transporter permease
GHKNIELH_00641 4.6e-177 oppF P Belongs to the ABC transporter superfamily
GHKNIELH_00642 9e-192 oppD P Belongs to the ABC transporter superfamily
GHKNIELH_00643 9.8e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GHKNIELH_00644 1.2e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GHKNIELH_00645 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GHKNIELH_00646 1.5e-26 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GHKNIELH_00647 2.6e-236 yloV S DAK2 domain fusion protein YloV
GHKNIELH_00648 1.4e-57 asp S Asp23 family, cell envelope-related function
GHKNIELH_00649 1.2e-18 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GHKNIELH_00650 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
GHKNIELH_00651 4.1e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GHKNIELH_00652 4.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GHKNIELH_00653 0.0 KLT serine threonine protein kinase
GHKNIELH_00654 7.8e-140 stp 3.1.3.16 T phosphatase
GHKNIELH_00655 1.9e-242 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GHKNIELH_00656 3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GHKNIELH_00657 2.3e-223 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GHKNIELH_00658 5.5e-14 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GHKNIELH_00659 1.5e-195 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GHKNIELH_00660 2.3e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GHKNIELH_00661 7.3e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
GHKNIELH_00662 1e-47
GHKNIELH_00663 6.7e-293 recN L May be involved in recombinational repair of damaged DNA
GHKNIELH_00664 5.4e-109 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GHKNIELH_00665 3.4e-33 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GHKNIELH_00666 1.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GHKNIELH_00667 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GHKNIELH_00668 7.2e-206 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GHKNIELH_00669 3.3e-62 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GHKNIELH_00670 1.4e-37 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GHKNIELH_00671 3.6e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GHKNIELH_00672 3.4e-14 yqhY S Asp23 family, cell envelope-related function
GHKNIELH_00673 5.6e-17 yqhY S Asp23 family, cell envelope-related function
GHKNIELH_00674 5e-93 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GHKNIELH_00675 6.4e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GHKNIELH_00676 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GHKNIELH_00677 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
GHKNIELH_00678 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
GHKNIELH_00679 4.8e-123 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GHKNIELH_00680 1.2e-74 S Uncharacterized protein conserved in bacteria (DUF2325)
GHKNIELH_00681 1e-138 S Uncharacterized protein conserved in bacteria (DUF2325)
GHKNIELH_00682 3.5e-12
GHKNIELH_00683 1.2e-62
GHKNIELH_00684 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GHKNIELH_00685 6.4e-91 S ECF-type riboflavin transporter, S component
GHKNIELH_00686 2.5e-147 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
GHKNIELH_00687 3.5e-82
GHKNIELH_00688 2.2e-122 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GHKNIELH_00689 2.5e-309 S Predicted membrane protein (DUF2207)
GHKNIELH_00690 4.4e-167 I Carboxylesterase family
GHKNIELH_00691 8.3e-151 M domain protein
GHKNIELH_00693 8.4e-114 UW LPXTG-motif cell wall anchor domain protein
GHKNIELH_00694 1.3e-94 infB UW LPXTG-motif cell wall anchor domain protein
GHKNIELH_00695 0.0 infB UW LPXTG-motif cell wall anchor domain protein
GHKNIELH_00696 5.4e-188 UW LPXTG-motif cell wall anchor domain protein
GHKNIELH_00697 4e-49 3.4.22.70 M Sortase family
GHKNIELH_00699 1e-47 K Transcriptional regulator, TetR family
GHKNIELH_00700 3.1e-14 K Transcriptional regulator, TetR family
GHKNIELH_00702 1.2e-210 pepC 3.4.22.40 E Peptidase C1-like family
GHKNIELH_00703 2.6e-12 pepC 3.4.22.40 E Peptidase C1-like family
GHKNIELH_00704 1.6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
GHKNIELH_00705 5.9e-112 oppA E ABC transporter substrate-binding protein
GHKNIELH_00706 5.7e-62 oppA E ABC transporter substrate-binding protein
GHKNIELH_00707 6.2e-142 oppA E ABC transporter substrate-binding protein
GHKNIELH_00708 1.9e-77 K MerR HTH family regulatory protein
GHKNIELH_00709 2.3e-265 lmrB EGP Major facilitator Superfamily
GHKNIELH_00710 1.6e-90 S Domain of unknown function (DUF4811)
GHKNIELH_00711 4.6e-129 ppm1 GT2 M Glycosyl transferase family 2
GHKNIELH_00712 3.2e-107 fic D Fic/DOC family
GHKNIELH_00713 6.2e-70
GHKNIELH_00714 1e-190 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GHKNIELH_00715 8.7e-81 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GHKNIELH_00716 1.2e-40 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GHKNIELH_00717 1.6e-288 V ABC transporter transmembrane region
GHKNIELH_00719 7.2e-141 S haloacid dehalogenase-like hydrolase
GHKNIELH_00720 0.0 pepN 3.4.11.2 E aminopeptidase
GHKNIELH_00721 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GHKNIELH_00722 4.6e-225 sptS 2.7.13.3 T Histidine kinase
GHKNIELH_00723 1.2e-115 K response regulator
GHKNIELH_00724 1.1e-112 2.7.6.5 T Region found in RelA / SpoT proteins
GHKNIELH_00725 1.1e-66 O OsmC-like protein
GHKNIELH_00726 2.3e-23 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GHKNIELH_00727 2.2e-116 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GHKNIELH_00728 1.6e-92 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GHKNIELH_00729 4.4e-180 E ABC transporter, ATP-binding protein
GHKNIELH_00730 1.2e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GHKNIELH_00731 2.8e-160 yihY S Belongs to the UPF0761 family
GHKNIELH_00732 1.9e-160 map 3.4.11.18 E Methionine Aminopeptidase
GHKNIELH_00733 6.5e-78 fld C Flavodoxin
GHKNIELH_00734 8.8e-87 gtcA S Teichoic acid glycosylation protein
GHKNIELH_00735 4.1e-23 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GHKNIELH_00736 2.7e-174 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GHKNIELH_00739 1.4e-101 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHKNIELH_00740 9.3e-36 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHKNIELH_00741 1.1e-76 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHKNIELH_00742 5.1e-22 yfmL 3.6.4.13 L DEAD DEAH box helicase
GHKNIELH_00743 3.1e-156 yfmL 3.6.4.13 L DEAD DEAH box helicase
GHKNIELH_00744 8.7e-65 M Glycosyl hydrolases family 25
GHKNIELH_00745 9e-44 M Glycosyl hydrolases family 25
GHKNIELH_00746 7.9e-71 potE E amino acid
GHKNIELH_00747 6.1e-149 potE E amino acid
GHKNIELH_00748 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GHKNIELH_00749 7.4e-209 yhdP S Transporter associated domain
GHKNIELH_00750 2e-58
GHKNIELH_00751 2.6e-47
GHKNIELH_00752 3.5e-73 C nitroreductase
GHKNIELH_00753 2.8e-28 C nitroreductase
GHKNIELH_00754 3.3e-97 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GHKNIELH_00755 2.9e-72 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GHKNIELH_00756 1.1e-12 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GHKNIELH_00757 1.1e-18 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GHKNIELH_00758 1.1e-214 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GHKNIELH_00759 1.1e-136 glcR K DeoR C terminal sensor domain
GHKNIELH_00760 7e-53 S Enterocin A Immunity
GHKNIELH_00761 8.9e-133 gntR K UbiC transcription regulator-associated domain protein
GHKNIELH_00762 5.9e-174 rihB 3.2.2.1 F Nucleoside
GHKNIELH_00763 1.9e-188 V ABC transporter transmembrane region
GHKNIELH_00765 3.5e-11 KLT Lanthionine synthetase C-like protein
GHKNIELH_00766 1.1e-36 KLT Lanthionine synthetase C-like protein
GHKNIELH_00767 3.5e-53
GHKNIELH_00768 1.8e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GHKNIELH_00769 1.3e-157 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GHKNIELH_00770 2.6e-85 dps P Belongs to the Dps family
GHKNIELH_00771 5.1e-279 S C4-dicarboxylate anaerobic carrier
GHKNIELH_00772 2.8e-60 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GHKNIELH_00773 1.9e-108 phoU P Plays a role in the regulation of phosphate uptake
GHKNIELH_00774 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GHKNIELH_00775 6.3e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GHKNIELH_00776 3e-24 pstA P Phosphate transport system permease protein PstA
GHKNIELH_00777 1.6e-62 pstA P Phosphate transport system permease protein PstA
GHKNIELH_00778 5.1e-08 pstA P Phosphate transport system permease protein PstA
GHKNIELH_00779 2.7e-33 pstC P probably responsible for the translocation of the substrate across the membrane
GHKNIELH_00780 3.5e-119 pstC P probably responsible for the translocation of the substrate across the membrane
GHKNIELH_00781 4.6e-160 pstS P Phosphate
GHKNIELH_00782 2.8e-96 K Acetyltransferase (GNAT) domain
GHKNIELH_00783 1.2e-129 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GHKNIELH_00784 2.5e-254 glnPH2 P ABC transporter permease
GHKNIELH_00785 5.5e-158 rssA S Phospholipase, patatin family
GHKNIELH_00786 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
GHKNIELH_00788 1.8e-53 S Enterocin A Immunity
GHKNIELH_00792 1.3e-45 S Enterocin A Immunity
GHKNIELH_00794 9.9e-98 M Transport protein ComB
GHKNIELH_00795 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GHKNIELH_00796 7.5e-183 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
GHKNIELH_00797 1.3e-124 manY G PTS system
GHKNIELH_00798 3.3e-172 manN G system, mannose fructose sorbose family IID component
GHKNIELH_00799 1.8e-65 manO S Domain of unknown function (DUF956)
GHKNIELH_00800 1.5e-253 yifK E Amino acid permease
GHKNIELH_00801 3.5e-231 yifK E Amino acid permease
GHKNIELH_00802 6.5e-136 puuD S peptidase C26
GHKNIELH_00803 3.1e-235 steT_1 E amino acid
GHKNIELH_00804 3.4e-191 asnA 6.3.1.1 F aspartate--ammonia ligase
GHKNIELH_00805 6e-152 EG EamA-like transporter family
GHKNIELH_00806 9.5e-228 yfnA E Amino Acid
GHKNIELH_00807 1e-130 cobQ S glutamine amidotransferase
GHKNIELH_00808 7.1e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GHKNIELH_00809 2.9e-142 ptp2 3.1.3.48 T Tyrosine phosphatase family
GHKNIELH_00810 4.7e-185 scrR K Transcriptional regulator, LacI family
GHKNIELH_00811 4.2e-299 scrB 3.2.1.26 GH32 G invertase
GHKNIELH_00812 0.0 scrA 2.7.1.199, 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
GHKNIELH_00813 6.5e-36
GHKNIELH_00814 2.5e-86 ymdB S Macro domain protein
GHKNIELH_00815 6.2e-296 V ABC transporter transmembrane region
GHKNIELH_00816 7e-124 puuD S peptidase C26
GHKNIELH_00817 4.2e-147 mdtG EGP Major facilitator Superfamily
GHKNIELH_00818 1.3e-75 mdtG EGP Major Facilitator Superfamily
GHKNIELH_00819 4e-156
GHKNIELH_00820 4.3e-71 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
GHKNIELH_00821 8e-156 2.7.7.12 C Domain of unknown function (DUF4931)
GHKNIELH_00822 4.1e-153 ybbH_2 K Helix-turn-helix domain, rpiR family
GHKNIELH_00823 5.3e-144 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
GHKNIELH_00824 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
GHKNIELH_00825 1.6e-252 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHKNIELH_00826 3.9e-162 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GHKNIELH_00827 6.2e-128
GHKNIELH_00828 8.5e-52
GHKNIELH_00829 1.2e-140 S Belongs to the UPF0246 family
GHKNIELH_00830 7e-141 aroD S Alpha/beta hydrolase family
GHKNIELH_00831 3.6e-114 G Phosphoglycerate mutase family
GHKNIELH_00832 6.7e-110 G phosphoglycerate mutase
GHKNIELH_00833 2.4e-92 ygfC K Bacterial regulatory proteins, tetR family
GHKNIELH_00834 6.7e-182 hrtB V ABC transporter permease
GHKNIELH_00835 5.2e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
GHKNIELH_00836 1e-54 K CAT RNA binding domain
GHKNIELH_00837 3e-75 K CAT RNA binding domain
GHKNIELH_00838 0.0 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GHKNIELH_00839 1e-125 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GHKNIELH_00840 1.1e-155 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GHKNIELH_00841 1e-265 pipD E Dipeptidase
GHKNIELH_00842 6.8e-37
GHKNIELH_00843 6.1e-106 K WHG domain
GHKNIELH_00844 1.1e-95 nqr 1.5.1.36 S reductase
GHKNIELH_00845 3.7e-99 azr 1.5.1.36 S NADPH-dependent FMN reductase
GHKNIELH_00846 3.7e-201 4.2.1.126 S Bacterial protein of unknown function (DUF871)
GHKNIELH_00847 5.7e-149 3.1.3.48 T Tyrosine phosphatase family
GHKNIELH_00848 4.1e-110 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GHKNIELH_00849 2.1e-60 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GHKNIELH_00850 8.4e-96 cvpA S Colicin V production protein
GHKNIELH_00851 7e-121 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
GHKNIELH_00852 2.4e-119 noc K Belongs to the ParB family
GHKNIELH_00853 3e-128 soj D Sporulation initiation inhibitor
GHKNIELH_00854 2.2e-154 spo0J K Belongs to the ParB family
GHKNIELH_00855 2.9e-43 yyzM S Bacterial protein of unknown function (DUF951)
GHKNIELH_00856 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GHKNIELH_00857 1.6e-149 XK27_01040 S Protein of unknown function (DUF1129)
GHKNIELH_00858 7.1e-298 V ABC transporter, ATP-binding protein
GHKNIELH_00859 0.0 V ABC transporter
GHKNIELH_00860 7.4e-121 K response regulator
GHKNIELH_00861 2.7e-200 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
GHKNIELH_00862 7.7e-307 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GHKNIELH_00863 1.2e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GHKNIELH_00864 4.1e-164 natA S ABC transporter, ATP-binding protein
GHKNIELH_00865 4e-218 natB CP ABC-2 family transporter protein
GHKNIELH_00866 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
GHKNIELH_00867 6.8e-136 fruR K DeoR C terminal sensor domain
GHKNIELH_00868 1.2e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GHKNIELH_00869 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
GHKNIELH_00870 6.6e-80 2.7.7.7 M domain protein
GHKNIELH_00871 0.0 2.7.7.7 M domain protein
GHKNIELH_00872 9.9e-138 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
GHKNIELH_00873 1.3e-157 psaA P Belongs to the bacterial solute-binding protein 9 family
GHKNIELH_00874 1.4e-116 fhuC P ABC transporter
GHKNIELH_00875 1.3e-77 znuB U ABC 3 transport family
GHKNIELH_00876 6.7e-38 znuB U ABC 3 transport family
GHKNIELH_00877 1.7e-121 lctP C L-lactate permease
GHKNIELH_00878 8.8e-105 lctP C L-lactate permease
GHKNIELH_00879 0.0 pepF E oligoendopeptidase F
GHKNIELH_00880 1.4e-209 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GHKNIELH_00881 6.9e-38
GHKNIELH_00882 4.3e-62
GHKNIELH_00883 4.3e-278 S ABC transporter
GHKNIELH_00884 1.9e-136 thrE S Putative threonine/serine exporter
GHKNIELH_00885 2.8e-79 S Threonine/Serine exporter, ThrE
GHKNIELH_00886 8.9e-40
GHKNIELH_00887 4.7e-60 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
GHKNIELH_00888 2.6e-80
GHKNIELH_00889 6.4e-176 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHKNIELH_00890 6.5e-81 nrdI F Belongs to the NrdI family
GHKNIELH_00891 2.4e-110
GHKNIELH_00892 1.3e-266 S O-antigen ligase like membrane protein
GHKNIELH_00893 5.3e-44
GHKNIELH_00894 6e-97 gmk2 2.7.4.8 F Guanylate kinase
GHKNIELH_00895 1.1e-114 M NlpC P60 family protein
GHKNIELH_00896 4.5e-230 S Putative peptidoglycan binding domain
GHKNIELH_00897 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GHKNIELH_00898 4.9e-276 E amino acid
GHKNIELH_00899 5.3e-133 cysA V ABC transporter, ATP-binding protein
GHKNIELH_00900 0.0 V FtsX-like permease family
GHKNIELH_00901 1.8e-124 pgm3 G Phosphoglycerate mutase family
GHKNIELH_00902 1.6e-26
GHKNIELH_00904 1.5e-33
GHKNIELH_00905 8.4e-150 xth 3.1.11.2 L exodeoxyribonuclease III
GHKNIELH_00906 1e-82 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
GHKNIELH_00907 6.4e-290 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
GHKNIELH_00908 4.5e-126 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GHKNIELH_00909 2.1e-143 rpiR1 K Helix-turn-helix domain, rpiR family
GHKNIELH_00910 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
GHKNIELH_00912 1e-116 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GHKNIELH_00913 2.5e-101 helD 3.6.4.12 L DNA helicase
GHKNIELH_00914 6.6e-290 helD 3.6.4.12 L DNA helicase
GHKNIELH_00915 1.8e-122 yvpB S Peptidase_C39 like family
GHKNIELH_00916 2.8e-105 E GDSL-like Lipase/Acylhydrolase
GHKNIELH_00917 1.8e-153 coaA 2.7.1.33 F Pantothenic acid kinase
GHKNIELH_00918 3.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GHKNIELH_00919 5.9e-15 fhaB M Rib/alpha-like repeat
GHKNIELH_00920 4.8e-22 fhaB M Rib/alpha-like repeat
GHKNIELH_00921 7.6e-30 fhaB M Rib/alpha-like repeat
GHKNIELH_00922 2.5e-47 fhaB M Rib/alpha-like repeat
GHKNIELH_00923 2.8e-91 licT K CAT RNA binding domain
GHKNIELH_00924 4.7e-32 licT K CAT RNA binding domain
GHKNIELH_00925 9.6e-43 bglP 2.7.1.211 G phosphotransferase system
GHKNIELH_00926 4.6e-155 EG EamA-like transporter family
GHKNIELH_00927 0.0 oppA E ABC transporter substrate-binding protein
GHKNIELH_00928 5.8e-118 2.7.1.191 G PTS system sorbose subfamily IIB component
GHKNIELH_00929 1e-37 2.7.1.191 G PTS system sorbose subfamily IIB component
GHKNIELH_00930 6.4e-140 G PTS system sorbose-specific iic component
GHKNIELH_00931 8.5e-145 G PTS system mannose/fructose/sorbose family IID component
GHKNIELH_00932 3.4e-62
GHKNIELH_00933 1.4e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GHKNIELH_00934 1.9e-203 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
GHKNIELH_00935 9.6e-237 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GHKNIELH_00936 1.8e-23 S PAS domain
GHKNIELH_00937 3.9e-90 S PAS domain
GHKNIELH_00938 9.8e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GHKNIELH_00939 2.1e-270 GM domain, Protein
GHKNIELH_00940 0.0 GM domain, Protein
GHKNIELH_00941 5.3e-144 pnuC H nicotinamide mononucleotide transporter
GHKNIELH_00942 2.1e-91 S PAS domain
GHKNIELH_00943 1.8e-245 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GHKNIELH_00944 1.5e-74 S Protein of unknown function (DUF3290)
GHKNIELH_00945 5.8e-112 yviA S Protein of unknown function (DUF421)
GHKNIELH_00946 1.6e-146 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GHKNIELH_00947 5.2e-181 dnaQ 2.7.7.7 L EXOIII
GHKNIELH_00948 3.2e-198 ltrA S Bacterial low temperature requirement A protein (LtrA)
GHKNIELH_00949 1.7e-156 dkg S reductase
GHKNIELH_00950 7.9e-157 endA F DNA RNA non-specific endonuclease
GHKNIELH_00951 9.8e-285 pipD E Dipeptidase
GHKNIELH_00952 3.8e-204 malK P ATPases associated with a variety of cellular activities
GHKNIELH_00953 2.1e-157 gtsB P ABC-type sugar transport systems, permease components
GHKNIELH_00954 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
GHKNIELH_00955 5.1e-248 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
GHKNIELH_00956 2.5e-239 G Bacterial extracellular solute-binding protein
GHKNIELH_00957 6.5e-39 ypaA S Protein of unknown function (DUF1304)
GHKNIELH_00958 8.2e-76 yybA 2.3.1.57 K Transcriptional regulator
GHKNIELH_00959 2e-86 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
GHKNIELH_00960 5.8e-79 yjcF S Acetyltransferase (GNAT) domain
GHKNIELH_00961 2e-102 UW Tetratricopeptide repeat
GHKNIELH_00962 1.6e-55
GHKNIELH_00963 3.9e-87 comGF U Putative Competence protein ComGF
GHKNIELH_00964 3.9e-170 ytxK 2.1.1.72 L N-6 DNA Methylase
GHKNIELH_00965 1e-226 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHKNIELH_00967 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
GHKNIELH_00968 7.6e-94 M Protein of unknown function (DUF3737)
GHKNIELH_00969 1.8e-220 patB 4.4.1.8 E Aminotransferase, class I
GHKNIELH_00970 2.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
GHKNIELH_00971 6e-47 S SdpI/YhfL protein family
GHKNIELH_00972 2e-129 K Transcriptional regulatory protein, C terminal
GHKNIELH_00973 2.6e-269 T PhoQ Sensor
GHKNIELH_00974 1.5e-292 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GHKNIELH_00975 5.2e-81 vanZ V VanZ like family
GHKNIELH_00976 1.9e-261 pgi 5.3.1.9 G Belongs to the GPI family
GHKNIELH_00977 3.8e-241 EGP Major facilitator Superfamily
GHKNIELH_00978 1.1e-69
GHKNIELH_00981 2.3e-195 ampC V Beta-lactamase
GHKNIELH_00982 1.1e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
GHKNIELH_00983 5.5e-112 tdk 2.7.1.21 F thymidine kinase
GHKNIELH_00984 1.7e-57 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GHKNIELH_00985 8.7e-122 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GHKNIELH_00986 4.6e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GHKNIELH_00987 1.7e-85 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GHKNIELH_00988 4.1e-80 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GHKNIELH_00989 1.5e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GHKNIELH_00990 1.1e-127 atpB C it plays a direct role in the translocation of protons across the membrane
GHKNIELH_00991 2.5e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GHKNIELH_00992 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GHKNIELH_00993 9.8e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GHKNIELH_00994 6.7e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GHKNIELH_00995 1.8e-22 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GHKNIELH_00996 1.5e-98 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GHKNIELH_00997 9.6e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GHKNIELH_00998 1.2e-71 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GHKNIELH_00999 5.4e-31 ywzB S Protein of unknown function (DUF1146)
GHKNIELH_01000 1.7e-179 mbl D Cell shape determining protein MreB Mrl
GHKNIELH_01001 6.8e-13 S DNA-directed RNA polymerase subunit beta
GHKNIELH_01002 2.6e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
GHKNIELH_01003 6.6e-34 S Protein of unknown function (DUF2969)
GHKNIELH_01004 5.2e-223 rodA D Belongs to the SEDS family
GHKNIELH_01005 5.2e-81 usp6 T universal stress protein
GHKNIELH_01007 1.4e-237 rarA L recombination factor protein RarA
GHKNIELH_01008 2.4e-83 yueI S Protein of unknown function (DUF1694)
GHKNIELH_01009 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GHKNIELH_01011 4.2e-290 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GHKNIELH_01012 1.1e-56 iscS2 2.8.1.7 E Aminotransferase class V
GHKNIELH_01013 1e-11 iscS2 2.8.1.7 E Aminotransferase class V
GHKNIELH_01014 1.6e-100 iscS2 2.8.1.7 E Aminotransferase class V
GHKNIELH_01015 6.1e-157 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GHKNIELH_01016 5.2e-63 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GHKNIELH_01017 4e-58 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GHKNIELH_01018 6e-55 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GHKNIELH_01019 1.4e-90 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
GHKNIELH_01020 7.1e-53 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
GHKNIELH_01021 0.0 3.6.3.8 P P-type ATPase
GHKNIELH_01022 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GHKNIELH_01023 3.5e-143 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GHKNIELH_01024 3.6e-79 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GHKNIELH_01025 2.7e-100 S Haloacid dehalogenase-like hydrolase
GHKNIELH_01026 9.2e-72 radC L DNA repair protein
GHKNIELH_01027 3.8e-30 radC L DNA repair protein
GHKNIELH_01028 2.7e-164 mreB D cell shape determining protein MreB
GHKNIELH_01029 1.8e-140 mreC M Involved in formation and maintenance of cell shape
GHKNIELH_01030 2.7e-94 mreD
GHKNIELH_01031 3.6e-13 S Protein of unknown function (DUF4044)
GHKNIELH_01032 2.7e-52 S Protein of unknown function (DUF3397)
GHKNIELH_01033 4.1e-77 mraZ K Belongs to the MraZ family
GHKNIELH_01034 1.7e-179 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GHKNIELH_01035 4.8e-55 ftsL D Cell division protein FtsL
GHKNIELH_01036 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
GHKNIELH_01037 1.2e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GHKNIELH_01038 1.1e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GHKNIELH_01039 1.8e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GHKNIELH_01040 3.4e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GHKNIELH_01041 1.2e-50 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GHKNIELH_01042 1.7e-149 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GHKNIELH_01043 1.1e-243 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GHKNIELH_01044 1.3e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GHKNIELH_01045 1.2e-27 yggT S YGGT family
GHKNIELH_01046 4e-133 ylmH S S4 domain protein
GHKNIELH_01047 8.2e-116 gpsB D DivIVA domain protein
GHKNIELH_01048 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GHKNIELH_01049 5.4e-25 cspA K 'Cold-shock' DNA-binding domain
GHKNIELH_01050 1.7e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
GHKNIELH_01051 1.4e-33
GHKNIELH_01052 1.1e-127 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GHKNIELH_01053 5.1e-215 iscS 2.8.1.7 E Aminotransferase class V
GHKNIELH_01054 1.8e-20 XK27_04120 S Putative amino acid metabolism
GHKNIELH_01055 7.4e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GHKNIELH_01056 1.2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
GHKNIELH_01057 1.9e-115 S Repeat protein
GHKNIELH_01058 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GHKNIELH_01059 8.6e-173 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
GHKNIELH_01060 8.4e-218 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GHKNIELH_01061 1.2e-30 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GHKNIELH_01062 2.3e-34 ykzG S Belongs to the UPF0356 family
GHKNIELH_01063 5.2e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GHKNIELH_01064 1.8e-95 typA T GTP-binding protein TypA
GHKNIELH_01065 9.5e-225 typA T GTP-binding protein TypA
GHKNIELH_01066 3.4e-46 ftsW D Belongs to the SEDS family
GHKNIELH_01067 2.5e-39 ftsW D Belongs to the SEDS family
GHKNIELH_01068 1.7e-18 ftsW D Belongs to the SEDS family
GHKNIELH_01069 5.8e-23 ylbG S UPF0298 protein
GHKNIELH_01070 7.2e-95 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
GHKNIELH_01071 2.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GHKNIELH_01072 3.1e-184 ylbL T Belongs to the peptidase S16 family
GHKNIELH_01073 4.1e-87 comEA L Competence protein ComEA
GHKNIELH_01074 0.0 comEC S Competence protein ComEC
GHKNIELH_01075 8.8e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
GHKNIELH_01076 4.4e-34 rpsT J Binds directly to 16S ribosomal RNA
GHKNIELH_01077 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GHKNIELH_01078 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GHKNIELH_01079 1.9e-158
GHKNIELH_01080 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GHKNIELH_01081 1.1e-52 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GHKNIELH_01082 1.8e-142 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GHKNIELH_01083 2.2e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GHKNIELH_01084 1.5e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
GHKNIELH_01085 9.7e-88 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GHKNIELH_01086 1.1e-81
GHKNIELH_01088 8.8e-116 frnE Q DSBA-like thioredoxin domain
GHKNIELH_01089 6e-78 S Domain of unknown function (DUF4767)
GHKNIELH_01090 3.6e-146
GHKNIELH_01091 2e-49
GHKNIELH_01092 8.4e-122 frnE Q DSBA-like thioredoxin domain
GHKNIELH_01093 1.8e-164
GHKNIELH_01094 2.1e-77 K DNA-templated transcription, initiation
GHKNIELH_01095 1.8e-152 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GHKNIELH_01096 1.7e-143 epsB M biosynthesis protein
GHKNIELH_01097 1.3e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
GHKNIELH_01098 2.3e-139 ywqE 3.1.3.48 GM PHP domain protein
GHKNIELH_01099 1.7e-111 rfbP M Bacterial sugar transferase
GHKNIELH_01100 2.9e-81 cpsF M Oligosaccharide biosynthesis protein Alg14 like
GHKNIELH_01101 1.7e-79 pssE S Glycosyltransferase family 28 C-terminal domain
GHKNIELH_01102 2.1e-126 M Glycosyltransferase sugar-binding region containing DXD motif
GHKNIELH_01103 2.6e-126 M Glycosyl transferase family 2
GHKNIELH_01104 4.4e-101 2.7.8.12 GT2 S glycosyl transferase family 2
GHKNIELH_01105 2.4e-131 M Glycosyl transferase family 2
GHKNIELH_01106 3.8e-26 glf 5.4.99.9 M UDP-galactopyranose mutase
GHKNIELH_01107 8.5e-168 glf 5.4.99.9 M UDP-galactopyranose mutase
GHKNIELH_01108 1.1e-86
GHKNIELH_01109 1.1e-221 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
GHKNIELH_01110 1e-150 S Acyltransferase family
GHKNIELH_01111 2.6e-58 L PFAM IS66 Orf2 family protein
GHKNIELH_01112 4.5e-22 L Transposase IS66 family
GHKNIELH_01113 3e-171 L Transposase IS66 family
GHKNIELH_01114 3.9e-30 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHKNIELH_01117 1.5e-219 E IrrE N-terminal-like domain
GHKNIELH_01118 3.1e-106 S Domain of unknown function (DUF4411)
GHKNIELH_01119 0.0 S KAP family P-loop domain
GHKNIELH_01120 3.7e-177 MA20_14895 S Conserved hypothetical protein 698
GHKNIELH_01121 1.1e-275 lsa S ABC transporter
GHKNIELH_01122 7.7e-82 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
GHKNIELH_01123 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GHKNIELH_01124 1.1e-133 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
GHKNIELH_01125 2.4e-51 S Protein of unknown function (DUF3021)
GHKNIELH_01126 2.9e-40 K LytTr DNA-binding domain
GHKNIELH_01127 1.3e-26 sprD D Domain of Unknown Function (DUF1542)
GHKNIELH_01128 0.0 sprD D Domain of Unknown Function (DUF1542)
GHKNIELH_01129 0.0 sprD D Domain of Unknown Function (DUF1542)
GHKNIELH_01131 2.7e-15 sprD D Domain of Unknown Function (DUF1542)
GHKNIELH_01133 9.4e-71 sprD D Domain of Unknown Function (DUF1542)
GHKNIELH_01134 6.2e-112 S Protein of unknown function (DUF1211)
GHKNIELH_01135 6e-12 S reductase
GHKNIELH_01136 1e-59 S reductase
GHKNIELH_01137 1.3e-110 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GHKNIELH_01138 3.2e-115 3.6.1.55 F NUDIX domain
GHKNIELH_01139 9.1e-127 T Transcriptional regulatory protein, C terminal
GHKNIELH_01140 6.5e-238 T GHKL domain
GHKNIELH_01141 1.1e-09 S Peptidase propeptide and YPEB domain
GHKNIELH_01142 5.8e-10 S Peptidase propeptide and YPEB domain
GHKNIELH_01143 1.1e-114 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
GHKNIELH_01144 9.9e-63 S Putative adhesin
GHKNIELH_01145 2.1e-247 brnQ U Component of the transport system for branched-chain amino acids
GHKNIELH_01146 2.3e-184 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GHKNIELH_01147 2.7e-252 lysC 2.7.2.4 E Belongs to the aspartokinase family
GHKNIELH_01148 2.1e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GHKNIELH_01149 4.4e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GHKNIELH_01150 3.7e-169 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GHKNIELH_01151 1e-15 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GHKNIELH_01152 5.2e-17 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GHKNIELH_01153 3.6e-39 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GHKNIELH_01154 2.2e-26 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GHKNIELH_01155 6.7e-99 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GHKNIELH_01156 4.1e-11 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GHKNIELH_01157 4.1e-151 aspC 2.6.1.1 E Aminotransferase
GHKNIELH_01158 4.7e-24 aspC 2.6.1.1 E Aminotransferase
GHKNIELH_01159 1.7e-39 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GHKNIELH_01160 2.7e-137 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GHKNIELH_01161 5.7e-39 sufC O FeS assembly ATPase SufC
GHKNIELH_01162 3.5e-91 sufC O FeS assembly ATPase SufC
GHKNIELH_01163 2.6e-222 sufD O FeS assembly protein SufD
GHKNIELH_01164 1.2e-230 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GHKNIELH_01165 1e-78 nifU C SUF system FeS assembly protein, NifU family
GHKNIELH_01166 1.7e-273 sufB O assembly protein SufB
GHKNIELH_01167 2.1e-54 yitW S Iron-sulfur cluster assembly protein
GHKNIELH_01168 5.6e-116 mntH P H( )-stimulated, divalent metal cation uptake system
GHKNIELH_01169 4e-142 mntH P H( )-stimulated, divalent metal cation uptake system
GHKNIELH_01170 2.7e-132 H Nodulation protein S (NodS)
GHKNIELH_01172 4.9e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GHKNIELH_01173 6.2e-44 S PFAM Archaeal ATPase
GHKNIELH_01174 1.2e-98 S PFAM Archaeal ATPase
GHKNIELH_01175 3.1e-31 S PFAM Archaeal ATPase
GHKNIELH_01176 1.9e-50 uvrA3 L excinuclease ABC, A subunit
GHKNIELH_01177 0.0 uvrA3 L excinuclease ABC, A subunit
GHKNIELH_01179 4e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
GHKNIELH_01180 6.2e-177 nss M transferase activity, transferring glycosyl groups
GHKNIELH_01181 1.4e-210 cycA E Amino acid permease
GHKNIELH_01182 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GHKNIELH_01183 1.5e-71
GHKNIELH_01184 1.1e-81 4.1.1.44 S decarboxylase
GHKNIELH_01185 4.1e-37 4.1.1.44 S decarboxylase
GHKNIELH_01186 0.0 S TerB-C domain
GHKNIELH_01187 3.2e-253 P P-loop Domain of unknown function (DUF2791)
GHKNIELH_01188 4.3e-112 lhr L DEAD DEAH box helicase
GHKNIELH_01189 4.4e-299 lhr L DEAD DEAH box helicase
GHKNIELH_01190 1.7e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GHKNIELH_01191 5.1e-37 S Uncharacterized protein conserved in bacteria (DUF2263)
GHKNIELH_01192 7.6e-79 S Uncharacterized protein conserved in bacteria (DUF2263)
GHKNIELH_01193 5.2e-162 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
GHKNIELH_01194 1.1e-17 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
GHKNIELH_01195 4.4e-163 yvgN C Aldo keto reductase
GHKNIELH_01197 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
GHKNIELH_01198 7.7e-262 hsdM 2.1.1.72 V type I restriction-modification system
GHKNIELH_01199 2.1e-94 3.1.21.3 V Type I restriction modification DNA specificity domain
GHKNIELH_01201 3.3e-89 K acetyltransferase
GHKNIELH_01202 2e-57 psiE S Phosphate-starvation-inducible E
GHKNIELH_01203 1.5e-132 S Putative ABC-transporter type IV
GHKNIELH_01204 6e-114 M LysM domain protein
GHKNIELH_01205 3.3e-92 M LysM domain protein
GHKNIELH_01207 2.3e-19 yjgN S Bacterial protein of unknown function (DUF898)
GHKNIELH_01208 3.6e-169 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
GHKNIELH_01209 1.3e-58 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GHKNIELH_01210 9e-113 K SIS domain
GHKNIELH_01211 2.4e-164 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
GHKNIELH_01214 1.9e-52 P Rhodanese Homology Domain
GHKNIELH_01215 2.7e-189
GHKNIELH_01216 3.6e-123 gntR1 K UTRA
GHKNIELH_01217 7.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
GHKNIELH_01218 1.6e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GHKNIELH_01219 2.7e-205 csaB M Glycosyl transferases group 1
GHKNIELH_01220 0.0 S Glycosyltransferase like family 2
GHKNIELH_01221 2.5e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GHKNIELH_01222 2.8e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GHKNIELH_01223 0.0 spoVK O ATPase family associated with various cellular activities (AAA)
GHKNIELH_01224 9.1e-276 pacL 3.6.3.8 P P-type ATPase
GHKNIELH_01225 2.4e-201 pacL 3.6.3.8 P P-type ATPase
GHKNIELH_01226 8.3e-226 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GHKNIELH_01227 1.3e-32 epsU S Polysaccharide biosynthesis protein
GHKNIELH_01228 5.8e-206 epsU S Polysaccharide biosynthesis protein
GHKNIELH_01229 1.2e-131 M Glycosyltransferase sugar-binding region containing DXD motif
GHKNIELH_01230 2.8e-84 ydcK S Belongs to the SprT family
GHKNIELH_01232 1.5e-101 S ECF transporter, substrate-specific component
GHKNIELH_01233 1.7e-111 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
GHKNIELH_01234 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GHKNIELH_01235 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GHKNIELH_01236 6.5e-207 camS S sex pheromone
GHKNIELH_01237 3.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GHKNIELH_01238 1.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GHKNIELH_01239 6e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GHKNIELH_01240 2e-166 yegS 2.7.1.107 G Lipid kinase
GHKNIELH_01242 2.9e-148 S hydrolase
GHKNIELH_01243 2.2e-26 UW Tetratricopeptide repeat
GHKNIELH_01244 1.6e-68 UW Tetratricopeptide repeat
GHKNIELH_01245 3.4e-75 UW Tetratricopeptide repeat
GHKNIELH_01246 3e-27 UW Tetratricopeptide repeat
GHKNIELH_01247 6.3e-27 UW Tetratricopeptide repeat
GHKNIELH_01248 0.0 GT2,GT4 M family 8
GHKNIELH_01249 5.4e-40 GT2,GT4 M family 8
GHKNIELH_01250 9.5e-166 GT2,GT4 M family 8
GHKNIELH_01251 3.4e-163 GT2,GT4 M family 8
GHKNIELH_01252 2.1e-118 ybhL S Belongs to the BI1 family
GHKNIELH_01253 6.3e-143 cbiQ P cobalt transport
GHKNIELH_01254 0.0 ykoD P ABC transporter, ATP-binding protein
GHKNIELH_01255 1.9e-95 S UPF0397 protein
GHKNIELH_01256 9e-161 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
GHKNIELH_01257 1.7e-241 nhaC C Na H antiporter NhaC
GHKNIELH_01258 4.4e-129 mutF V ABC transporter, ATP-binding protein
GHKNIELH_01259 2.1e-120 spaE S ABC-2 family transporter protein
GHKNIELH_01260 3e-143 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHKNIELH_01261 4.2e-86 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHKNIELH_01262 4.4e-106
GHKNIELH_01263 4.1e-128 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
GHKNIELH_01264 1.1e-195 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
GHKNIELH_01265 7.9e-35 copZ C Heavy-metal-associated domain
GHKNIELH_01266 5.2e-93 dps P Belongs to the Dps family
GHKNIELH_01267 8.1e-114 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
GHKNIELH_01268 1.9e-39 ung2 3.2.2.27 L Uracil-DNA glycosylase
GHKNIELH_01270 1.6e-196 V Beta-lactamase
GHKNIELH_01271 5.1e-110 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
GHKNIELH_01272 1.1e-24 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GHKNIELH_01273 2.8e-94
GHKNIELH_01274 1.1e-44 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GHKNIELH_01275 5e-27 GH23 S M26 IgA1-specific Metallo-endopeptidase C-terminal region
GHKNIELH_01276 0.0 GH23 S M26 IgA1-specific Metallo-endopeptidase C-terminal region
GHKNIELH_01277 6.7e-64 GH23 S M26 IgA1-specific Metallo-endopeptidase C-terminal region
GHKNIELH_01279 7.1e-158 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GHKNIELH_01280 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GHKNIELH_01281 9.5e-56 yheA S Belongs to the UPF0342 family
GHKNIELH_01282 4.4e-217 yhaO L Ser Thr phosphatase family protein
GHKNIELH_01283 0.0 L AAA domain
GHKNIELH_01284 8.7e-184 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
GHKNIELH_01285 2.1e-147 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GHKNIELH_01286 9.5e-24 S YtxH-like protein
GHKNIELH_01287 2e-51
GHKNIELH_01288 3.5e-76 hit FG Scavenger mRNA decapping enzyme C-term binding
GHKNIELH_01289 9.7e-135 ecsA V ABC transporter, ATP-binding protein
GHKNIELH_01290 1.3e-224 ecsB U ABC transporter
GHKNIELH_01291 2.9e-119 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GHKNIELH_01292 4.3e-62
GHKNIELH_01293 4.7e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GHKNIELH_01294 4.1e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GHKNIELH_01295 2.3e-84 cutC P Participates in the control of copper homeostasis
GHKNIELH_01296 3.2e-34 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GHKNIELH_01297 1.7e-190 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GHKNIELH_01298 2.5e-127 K UTRA
GHKNIELH_01299 1.4e-130 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GHKNIELH_01300 1.8e-242 G Bacterial extracellular solute-binding protein
GHKNIELH_01301 2.7e-120 baeR K helix_turn_helix, Lux Regulon
GHKNIELH_01302 4.1e-181 baeS F Sensor histidine kinase
GHKNIELH_01303 6.2e-30 baeS F Sensor histidine kinase
GHKNIELH_01304 5.2e-173 rbsB G Periplasmic binding protein domain
GHKNIELH_01305 8.8e-75 levA G PTS system fructose IIA component
GHKNIELH_01306 3.9e-95 2.7.1.191 G PTS system sorbose subfamily IIB component
GHKNIELH_01307 9.4e-142 M PTS system sorbose-specific iic component
GHKNIELH_01308 1.8e-153 levD G PTS system mannose/fructose/sorbose family IID component
GHKNIELH_01309 1.2e-49
GHKNIELH_01310 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GHKNIELH_01311 2.2e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GHKNIELH_01312 6e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GHKNIELH_01313 1.7e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GHKNIELH_01314 9.3e-237 dnaB L Replication initiation and membrane attachment
GHKNIELH_01315 5.4e-156 dnaI L Primosomal protein DnaI
GHKNIELH_01316 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GHKNIELH_01317 1.2e-23 K LytTr DNA-binding domain
GHKNIELH_01318 1.8e-37 S Protein of unknown function (DUF3021)
GHKNIELH_01319 2.3e-54 V ABC transporter
GHKNIELH_01320 9.4e-55 V ABC transporter
GHKNIELH_01321 7.2e-93 S domain protein
GHKNIELH_01322 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GHKNIELH_01323 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GHKNIELH_01324 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GHKNIELH_01325 5.8e-167 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GHKNIELH_01326 2.1e-88 yqeG S HAD phosphatase, family IIIA
GHKNIELH_01327 1e-209 yqeH S Ribosome biogenesis GTPase YqeH
GHKNIELH_01328 2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GHKNIELH_01329 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
GHKNIELH_01330 3.7e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GHKNIELH_01331 9.7e-112 ylbM S Belongs to the UPF0348 family
GHKNIELH_01332 2.5e-95 ylbM S Belongs to the UPF0348 family
GHKNIELH_01333 6.5e-91 yceD S Uncharacterized ACR, COG1399
GHKNIELH_01334 1.2e-129 K response regulator
GHKNIELH_01335 1e-279 arlS 2.7.13.3 T Histidine kinase
GHKNIELH_01336 2.7e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GHKNIELH_01337 1.5e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GHKNIELH_01338 2.8e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHKNIELH_01339 1.5e-61 yodB K Transcriptional regulator, HxlR family
GHKNIELH_01340 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GHKNIELH_01341 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GHKNIELH_01342 1.3e-103 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GHKNIELH_01343 3.5e-79 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GHKNIELH_01344 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GHKNIELH_01345 0.0 S membrane
GHKNIELH_01346 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
GHKNIELH_01347 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GHKNIELH_01348 2.5e-37 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GHKNIELH_01349 4e-119 gluP 3.4.21.105 S Rhomboid family
GHKNIELH_01350 7.9e-35 yqgQ S Bacterial protein of unknown function (DUF910)
GHKNIELH_01351 2e-57 yqhL P Rhodanese-like protein
GHKNIELH_01352 8.1e-19 S Protein of unknown function (DUF3042)
GHKNIELH_01353 2e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GHKNIELH_01354 5.1e-259 glnA 6.3.1.2 E glutamine synthetase
GHKNIELH_01355 1.1e-206 EGP Major facilitator Superfamily
GHKNIELH_01356 4.8e-151 S haloacid dehalogenase-like hydrolase
GHKNIELH_01358 1.1e-178 D Alpha beta
GHKNIELH_01359 9.3e-217 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
GHKNIELH_01360 3.1e-218 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GHKNIELH_01361 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
GHKNIELH_01362 2.2e-108 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHKNIELH_01363 1.9e-45 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHKNIELH_01364 5.4e-79 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHKNIELH_01365 7.8e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
GHKNIELH_01366 2.4e-112 ygaC J Belongs to the UPF0374 family
GHKNIELH_01367 7e-89
GHKNIELH_01368 8.8e-78
GHKNIELH_01369 4.2e-74 hlyX S Transporter associated domain
GHKNIELH_01370 1.5e-68 hlyX S Transporter associated domain
GHKNIELH_01371 5.1e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GHKNIELH_01372 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
GHKNIELH_01373 3.3e-86 clpE O Belongs to the ClpA ClpB family
GHKNIELH_01374 5.3e-244 clpE O Belongs to the ClpA ClpB family
GHKNIELH_01375 5.9e-25
GHKNIELH_01376 4.2e-40 ptsH G phosphocarrier protein HPR
GHKNIELH_01377 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GHKNIELH_01378 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GHKNIELH_01379 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GHKNIELH_01380 2.4e-164 coiA 3.6.4.12 S Competence protein
GHKNIELH_01381 9.1e-107 yjbH Q Thioredoxin
GHKNIELH_01382 1.9e-112 yjbK S CYTH
GHKNIELH_01383 5.2e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
GHKNIELH_01384 2.5e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GHKNIELH_01385 3.2e-158 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GHKNIELH_01386 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
GHKNIELH_01387 2.3e-234 N Uncharacterized conserved protein (DUF2075)
GHKNIELH_01388 3.7e-87 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
GHKNIELH_01389 3.1e-62 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
GHKNIELH_01390 4.9e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
GHKNIELH_01391 1.5e-209 yubA S AI-2E family transporter
GHKNIELH_01392 4.6e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GHKNIELH_01393 1.7e-75 WQ51_03320 S Protein of unknown function (DUF1149)
GHKNIELH_01394 1e-92 ftsK D Belongs to the FtsK SpoIIIE SftA family
GHKNIELH_01395 4.5e-297 ftsK D Belongs to the FtsK SpoIIIE SftA family
GHKNIELH_01396 1.6e-76 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
GHKNIELH_01397 4.1e-116 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
GHKNIELH_01398 9.2e-231 S Peptidase M16
GHKNIELH_01399 3.7e-131 IQ Enoyl-(Acyl carrier protein) reductase
GHKNIELH_01400 1.9e-115 ymfM S Helix-turn-helix domain
GHKNIELH_01401 3e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GHKNIELH_01402 3.5e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GHKNIELH_01403 9.7e-185 rny S Endoribonuclease that initiates mRNA decay
GHKNIELH_01404 2.2e-70 tagO 2.7.8.33, 2.7.8.35 M transferase
GHKNIELH_01405 7.2e-114 tagO 2.7.8.33, 2.7.8.35 M transferase
GHKNIELH_01406 1.2e-115 yvyE 3.4.13.9 S YigZ family
GHKNIELH_01407 3.2e-225 comFA L Helicase C-terminal domain protein
GHKNIELH_01408 3.1e-124 comFC S Competence protein
GHKNIELH_01409 1.3e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GHKNIELH_01410 6.5e-260 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GHKNIELH_01411 1.3e-171 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GHKNIELH_01412 3.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GHKNIELH_01413 7.6e-24
GHKNIELH_01414 4.7e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GHKNIELH_01415 1.2e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GHKNIELH_01416 3.3e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GHKNIELH_01417 6e-132 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GHKNIELH_01418 3.8e-16 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GHKNIELH_01419 2.4e-157 lacR K Transcriptional regulator
GHKNIELH_01421 1.8e-32 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GHKNIELH_01422 4e-91 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GHKNIELH_01423 2.4e-254 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GHKNIELH_01424 6.1e-161 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GHKNIELH_01425 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GHKNIELH_01426 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GHKNIELH_01427 4.2e-186 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GHKNIELH_01428 2e-294 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GHKNIELH_01429 3.6e-15 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GHKNIELH_01430 1.8e-90 S Short repeat of unknown function (DUF308)
GHKNIELH_01431 1.9e-30 rapZ S Displays ATPase and GTPase activities
GHKNIELH_01432 3.3e-118 rapZ S Displays ATPase and GTPase activities
GHKNIELH_01433 5.8e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GHKNIELH_01434 6.2e-171 whiA K May be required for sporulation
GHKNIELH_01435 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GHKNIELH_01436 1.3e-38 ycaM E amino acid
GHKNIELH_01437 1.8e-204 ycaM E amino acid
GHKNIELH_01439 1.4e-187 cggR K Putative sugar-binding domain
GHKNIELH_01440 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GHKNIELH_01441 4.6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GHKNIELH_01442 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GHKNIELH_01443 6.2e-182 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHKNIELH_01444 7.6e-49 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHKNIELH_01445 1.9e-28 secG U Preprotein translocase
GHKNIELH_01446 9.9e-46 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GHKNIELH_01447 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GHKNIELH_01448 8.7e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GHKNIELH_01449 4.2e-106 3.2.2.20 K acetyltransferase
GHKNIELH_01450 1.2e-76
GHKNIELH_01451 8.1e-41
GHKNIELH_01452 6.8e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
GHKNIELH_01453 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GHKNIELH_01454 4.2e-119 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GHKNIELH_01455 2.7e-28 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GHKNIELH_01456 2.2e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
GHKNIELH_01457 1.2e-99 dnaQ 2.7.7.7 L DNA polymerase III
GHKNIELH_01458 9e-167 murB 1.3.1.98 M Cell wall formation
GHKNIELH_01459 8.4e-97 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GHKNIELH_01460 4.5e-88 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GHKNIELH_01461 1.2e-130 potB P ABC transporter permease
GHKNIELH_01462 9.8e-53 potC P ABC transporter permease
GHKNIELH_01463 3.2e-40 potC P ABC transporter permease
GHKNIELH_01464 1e-19 potD P ABC transporter
GHKNIELH_01465 5.5e-166 potD P ABC transporter
GHKNIELH_01466 2.9e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GHKNIELH_01467 4.4e-172 ybbR S YbbR-like protein
GHKNIELH_01468 7.7e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GHKNIELH_01469 4.7e-126 S Sucrose-6F-phosphate phosphohydrolase
GHKNIELH_01470 7.7e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GHKNIELH_01471 4.2e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GHKNIELH_01472 4.5e-198 S Putative adhesin
GHKNIELH_01473 4.8e-115
GHKNIELH_01474 8e-148 yisY 1.11.1.10 S Alpha/beta hydrolase family
GHKNIELH_01475 1.8e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
GHKNIELH_01476 1.5e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GHKNIELH_01477 4e-95 S VanZ like family
GHKNIELH_01478 1.5e-132 yebC K Transcriptional regulatory protein
GHKNIELH_01479 4.2e-178 comGA NU Type II IV secretion system protein
GHKNIELH_01480 6.8e-148 comGB NU type II secretion system
GHKNIELH_01481 1.2e-40 comGC U Required for transformation and DNA binding
GHKNIELH_01482 1.4e-10 2.7.1.12 G gluconokinase activity
GHKNIELH_01483 2.4e-47 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GHKNIELH_01484 5e-28 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GHKNIELH_01485 2.3e-78 K Transcriptional regulator
GHKNIELH_01486 3.7e-174 1.1.1.1 C nadph quinone reductase
GHKNIELH_01487 2.9e-82 XK27_09675 K Acetyltransferase (GNAT) domain
GHKNIELH_01488 1.4e-63 S Protein of unknown function (DUF3021)
GHKNIELH_01489 2.2e-73 K LytTr DNA-binding domain
GHKNIELH_01490 2.2e-146 cylB V ABC-2 type transporter
GHKNIELH_01491 2e-152 cylA V ABC transporter
GHKNIELH_01492 7.8e-200 ywhK S Membrane
GHKNIELH_01493 4.8e-27 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GHKNIELH_01494 1.2e-08
GHKNIELH_01495 4.7e-23 K Helix-turn-helix XRE-family like proteins
GHKNIELH_01496 2e-123 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
GHKNIELH_01497 7.2e-36 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
GHKNIELH_01498 5.7e-58 hxlR K Transcriptional regulator, HxlR family
GHKNIELH_01499 5e-56 yjdF S Protein of unknown function (DUF2992)
GHKNIELH_01500 3.9e-93 K Bacterial regulatory proteins, tetR family
GHKNIELH_01501 3.2e-112 1.6.5.2 S NADPH-dependent FMN reductase
GHKNIELH_01502 1.7e-171 K Helix-turn-helix
GHKNIELH_01503 1.7e-93 yxkA S Phosphatidylethanolamine-binding protein
GHKNIELH_01504 9.8e-112 K transcriptional regulator
GHKNIELH_01505 9.4e-12
GHKNIELH_01506 2e-172 L Belongs to the 'phage' integrase family
GHKNIELH_01507 4.3e-26 S Domain of unknown function (DUF3173)
GHKNIELH_01511 1.3e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GHKNIELH_01512 7.6e-186 arsB 1.20.4.1 P Sodium Bile acid symporter family
GHKNIELH_01513 5.4e-52 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
GHKNIELH_01514 2.1e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GHKNIELH_01515 3e-131 K Psort location CytoplasmicMembrane, score
GHKNIELH_01516 3.8e-102 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GHKNIELH_01517 3.9e-235 pbuX F xanthine permease
GHKNIELH_01518 2.9e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GHKNIELH_01519 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GHKNIELH_01520 2.5e-63 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GHKNIELH_01521 1.6e-73 S Domain of unknown function (DUF1934)
GHKNIELH_01522 1.5e-266 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
GHKNIELH_01523 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
GHKNIELH_01524 2.4e-153 malG P ABC transporter permease
GHKNIELH_01525 5e-254 malF P Binding-protein-dependent transport system inner membrane component
GHKNIELH_01526 7.4e-217 malE G Bacterial extracellular solute-binding protein
GHKNIELH_01527 2.7e-210 msmX P Belongs to the ABC transporter superfamily
GHKNIELH_01528 8.1e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
GHKNIELH_01529 1.2e-39 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
GHKNIELH_01530 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
GHKNIELH_01531 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
GHKNIELH_01532 1.1e-214 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
GHKNIELH_01533 2.2e-104 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
GHKNIELH_01534 1.3e-60 yvdE K helix_turn _helix lactose operon repressor
GHKNIELH_01535 8.4e-42 yvdE K helix_turn _helix lactose operon repressor
GHKNIELH_01536 1.1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHKNIELH_01537 3.7e-46 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GHKNIELH_01538 5.9e-150 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GHKNIELH_01539 1.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
GHKNIELH_01540 2.2e-35 veg S Biofilm formation stimulator VEG
GHKNIELH_01541 3.6e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GHKNIELH_01542 1.2e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GHKNIELH_01543 2.3e-147 tatD L hydrolase, TatD family
GHKNIELH_01544 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GHKNIELH_01545 8.5e-182 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
GHKNIELH_01546 4e-99 S TPM domain
GHKNIELH_01547 5.6e-91 comEB 3.5.4.12 F MafB19-like deaminase
GHKNIELH_01548 2e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
GHKNIELH_01549 1.2e-114 E Belongs to the SOS response-associated peptidase family
GHKNIELH_01551 1.8e-116
GHKNIELH_01552 2.2e-154 ypbG 2.7.1.2 GK ROK family
GHKNIELH_01553 1e-278 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GHKNIELH_01554 6.1e-263 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHKNIELH_01555 7.6e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
GHKNIELH_01556 2.1e-41
GHKNIELH_01557 1.5e-50 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
GHKNIELH_01558 1e-133 gmuR K UTRA
GHKNIELH_01559 1.7e-229 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GHKNIELH_01560 6.2e-37 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GHKNIELH_01561 2.4e-62 S Domain of unknown function (DUF3284)
GHKNIELH_01562 4.8e-27 yydK K UTRA
GHKNIELH_01563 1.1e-18 yydK K UTRA
GHKNIELH_01564 6.3e-241 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHKNIELH_01565 7.5e-83
GHKNIELH_01566 8.4e-292 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GHKNIELH_01567 2.7e-73 hsp O Belongs to the small heat shock protein (HSP20) family
GHKNIELH_01568 1.2e-74 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GHKNIELH_01569 9e-33
GHKNIELH_01570 3.3e-255 pepC 3.4.22.40 E aminopeptidase
GHKNIELH_01571 8.5e-42 ps301 K sequence-specific DNA binding
GHKNIELH_01572 2.4e-28 S Motility quorum-sensing regulator, toxin of MqsA
GHKNIELH_01573 1.7e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GHKNIELH_01574 8.5e-259 pepC 3.4.22.40 E aminopeptidase
GHKNIELH_01576 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GHKNIELH_01577 0.0 XK27_08315 M Sulfatase
GHKNIELH_01578 8.1e-79 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GHKNIELH_01579 1.4e-22 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GHKNIELH_01580 3.3e-195 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GHKNIELH_01581 9.4e-118 yqhA G Aldose 1-epimerase
GHKNIELH_01582 1.9e-12 yqhA G Aldose 1-epimerase
GHKNIELH_01583 1.6e-152 glcU U sugar transport
GHKNIELH_01584 1e-117
GHKNIELH_01585 7.3e-158 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
GHKNIELH_01586 3.4e-71 2.4.1.83 GT2 S GtrA-like protein
GHKNIELH_01587 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GHKNIELH_01588 8.1e-48 S HicB_like antitoxin of bacterial toxin-antitoxin system
GHKNIELH_01589 1.1e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GHKNIELH_01590 1.2e-73 S PAS domain
GHKNIELH_01591 4.8e-143
GHKNIELH_01592 1.2e-140
GHKNIELH_01593 8.3e-179 S Oxidoreductase family, NAD-binding Rossmann fold
GHKNIELH_01594 0.0 yjbQ P TrkA C-terminal domain protein
GHKNIELH_01595 2.4e-142 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
GHKNIELH_01596 5.4e-57 lysA2 M Glycosyl hydrolases family 25
GHKNIELH_01597 9.9e-194 lysA2 M Glycosyl hydrolases family 25
GHKNIELH_01598 7.7e-214 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GHKNIELH_01599 8.2e-35 S Protein of unknown function (DUF2922)
GHKNIELH_01600 1.9e-115
GHKNIELH_01601 1e-72
GHKNIELH_01602 6.5e-282 kup P Transport of potassium into the cell
GHKNIELH_01603 2e-28 kup P Transport of potassium into the cell
GHKNIELH_01604 0.0 kup P Transport of potassium into the cell
GHKNIELH_01605 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
GHKNIELH_01606 0.0 S Bacterial membrane protein, YfhO
GHKNIELH_01607 1.1e-94 pepO 3.4.24.71 O Peptidase family M13
GHKNIELH_01608 9e-270 pepO 3.4.24.71 O Peptidase family M13
GHKNIELH_01609 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GHKNIELH_01610 3.7e-168 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
GHKNIELH_01611 4.4e-135 rpl K Helix-turn-helix domain, rpiR family
GHKNIELH_01612 5.9e-175 D nuclear chromosome segregation
GHKNIELH_01613 1.4e-184 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
GHKNIELH_01614 1.5e-225 yttB EGP Major facilitator Superfamily
GHKNIELH_01615 7e-228 XK27_04775 S PAS domain
GHKNIELH_01616 1.3e-102 S Iron-sulfur cluster assembly protein
GHKNIELH_01617 6.9e-130 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHKNIELH_01618 1.6e-107 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GHKNIELH_01619 5.2e-234 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GHKNIELH_01620 3.6e-62 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GHKNIELH_01621 9.2e-155 yxbA 6.3.1.12 S ATP-grasp enzyme
GHKNIELH_01622 2.4e-101 yxbA 6.3.1.12 S ATP-grasp enzyme
GHKNIELH_01623 0.0 asnB 6.3.5.4 E Asparagine synthase
GHKNIELH_01624 3.1e-275 S Calcineurin-like phosphoesterase
GHKNIELH_01625 1.9e-83
GHKNIELH_01626 4.6e-146 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
GHKNIELH_01627 5.4e-131 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
GHKNIELH_01628 9.6e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GHKNIELH_01629 9.8e-169 phnD P Phosphonate ABC transporter
GHKNIELH_01631 1e-87 uspA T universal stress protein
GHKNIELH_01632 2.8e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
GHKNIELH_01633 1.1e-130 XK27_08440 K UTRA domain
GHKNIELH_01634 3.4e-100 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GHKNIELH_01635 5.6e-87 ntd 2.4.2.6 F Nucleoside
GHKNIELH_01636 6.8e-215 S zinc-ribbon domain
GHKNIELH_01637 7.9e-67 2.7.1.191 G PTS system fructose IIA component
GHKNIELH_01638 7.1e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
GHKNIELH_01639 3.4e-129 XK27_08455 G PTS system sorbose-specific iic component
GHKNIELH_01640 1.3e-82 2.7.1.191 G PTS system sorbose subfamily IIB component
GHKNIELH_01641 1.7e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GHKNIELH_01642 2.8e-213 agaS G SIS domain
GHKNIELH_01643 3.2e-127 XK27_08435 K UTRA
GHKNIELH_01644 0.0 G Belongs to the glycosyl hydrolase 31 family
GHKNIELH_01645 4.6e-154 I alpha/beta hydrolase fold
GHKNIELH_01646 2.2e-118 yibF S overlaps another CDS with the same product name
GHKNIELH_01647 8.9e-169 yibE S overlaps another CDS with the same product name
GHKNIELH_01648 2.7e-272 yjcE P Sodium proton antiporter
GHKNIELH_01649 6.8e-77
GHKNIELH_01650 2.4e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GHKNIELH_01651 5.4e-265 S Cysteine-rich secretory protein family
GHKNIELH_01652 2.4e-121
GHKNIELH_01653 2.2e-114 luxT K Bacterial regulatory proteins, tetR family
GHKNIELH_01654 1.8e-240 cycA E Amino acid permease
GHKNIELH_01655 4.5e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHKNIELH_01656 1.2e-61
GHKNIELH_01657 9.9e-123 S Alpha/beta hydrolase family
GHKNIELH_01658 8e-154 epsV 2.7.8.12 S glycosyl transferase family 2
GHKNIELH_01659 4.8e-158 ypuA S Protein of unknown function (DUF1002)
GHKNIELH_01661 1.2e-54 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHKNIELH_01662 1.6e-68 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHKNIELH_01663 1.7e-173 S Alpha/beta hydrolase of unknown function (DUF915)
GHKNIELH_01664 2.1e-123 yugP S Putative neutral zinc metallopeptidase
GHKNIELH_01665 1.1e-288 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHKNIELH_01666 7.5e-80
GHKNIELH_01667 4.2e-135 cobB K SIR2 family
GHKNIELH_01668 9.2e-87 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
GHKNIELH_01669 3.6e-124 terC P Integral membrane protein TerC family
GHKNIELH_01670 1.7e-63 yeaO S Protein of unknown function, DUF488
GHKNIELH_01671 5.9e-117 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
GHKNIELH_01672 2.5e-297 glnP P ABC transporter permease
GHKNIELH_01673 2.5e-138 glnQ E ABC transporter, ATP-binding protein
GHKNIELH_01674 4.4e-45
GHKNIELH_01675 1.3e-162 L HNH nucleases
GHKNIELH_01676 4.5e-120 yfbR S HD containing hydrolase-like enzyme
GHKNIELH_01677 2.2e-199 G Glycosyl hydrolases family 8
GHKNIELH_01678 3.6e-241 ydaM M Glycosyl transferase
GHKNIELH_01680 1.7e-119
GHKNIELH_01681 1.7e-16
GHKNIELH_01682 5.8e-65 S Iron-sulphur cluster biosynthesis
GHKNIELH_01683 5.6e-179 ybiR P Citrate transporter
GHKNIELH_01684 1.6e-89 lemA S LemA family
GHKNIELH_01685 4.5e-163 htpX O Belongs to the peptidase M48B family
GHKNIELH_01686 1.5e-161 K helix_turn_helix, arabinose operon control protein
GHKNIELH_01687 7.9e-97 S ABC-type cobalt transport system, permease component
GHKNIELH_01688 8.2e-241 cbiO1 S ABC transporter, ATP-binding protein
GHKNIELH_01689 5.6e-110 P Cobalt transport protein
GHKNIELH_01690 1.2e-52 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GHKNIELH_01691 1.1e-15 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GHKNIELH_01692 6.4e-176 htrA 3.4.21.107 O serine protease
GHKNIELH_01693 3.7e-148 vicX 3.1.26.11 S domain protein
GHKNIELH_01694 6.7e-145 yycI S YycH protein
GHKNIELH_01695 1.9e-250 yycH S YycH protein
GHKNIELH_01696 0.0 vicK 2.7.13.3 T Histidine kinase
GHKNIELH_01697 2.6e-129 K response regulator
GHKNIELH_01700 4.1e-144 arbV 2.3.1.51 I Acyl-transferase
GHKNIELH_01701 1.9e-152 arbx M Glycosyl transferase family 8
GHKNIELH_01702 1.6e-182 arbY M Glycosyl transferase family 8
GHKNIELH_01703 1.2e-182 arbY M Glycosyl transferase family 8
GHKNIELH_01704 2.8e-162 arbZ I Phosphate acyltransferases
GHKNIELH_01705 5.5e-245 yhjX_2 P Major Facilitator Superfamily
GHKNIELH_01706 2e-247 yhjX_2 P Major Facilitator Superfamily
GHKNIELH_01707 1.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
GHKNIELH_01708 1.2e-63 S Peptidase propeptide and YPEB domain
GHKNIELH_01709 1.6e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
GHKNIELH_01710 1.3e-134 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GHKNIELH_01711 8.9e-128 brnQ U Component of the transport system for branched-chain amino acids
GHKNIELH_01712 2.1e-86 brnQ U Component of the transport system for branched-chain amino acids
GHKNIELH_01713 9.5e-269 1.3.5.4 C FAD binding domain
GHKNIELH_01714 5.1e-73 1.3.5.4 C FAD binding domain
GHKNIELH_01715 8.9e-170 K LysR substrate binding domain
GHKNIELH_01716 4.8e-271 E amino acid
GHKNIELH_01717 5.4e-145 3.1.31.1 M domain protein
GHKNIELH_01718 0.0 3.1.31.1 M domain protein
GHKNIELH_01719 3.5e-146 infB UW LPXTG-motif cell wall anchor domain protein
GHKNIELH_01720 9.5e-72
GHKNIELH_01722 2.4e-52 S LexA-binding, inner membrane-associated putative hydrolase
GHKNIELH_01723 8.9e-24 K LysR substrate binding domain
GHKNIELH_01724 6.1e-62 K LysR substrate binding domain
GHKNIELH_01725 1.3e-60 lacX 5.1.3.3 G Aldose 1-epimerase
GHKNIELH_01726 9.8e-77 lacX 5.1.3.3 G Aldose 1-epimerase
GHKNIELH_01727 3.1e-251 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GHKNIELH_01728 4.3e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GHKNIELH_01729 2.6e-169 xerC D Phage integrase, N-terminal SAM-like domain
GHKNIELH_01730 2.6e-194 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GHKNIELH_01731 2.1e-37 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GHKNIELH_01732 2.6e-283 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GHKNIELH_01733 2.5e-101 M lysozyme activity
GHKNIELH_01735 4.8e-12
GHKNIELH_01737 1.7e-50 L Putative transposase DNA-binding domain
GHKNIELH_01738 1.5e-133 L Putative transposase DNA-binding domain
GHKNIELH_01740 8e-58 dnaC L IstB-like ATP binding protein
GHKNIELH_01741 3.6e-46 ybl78 L DnaD domain protein
GHKNIELH_01742 1.4e-42 S ERF superfamily
GHKNIELH_01744 4.7e-51 S Protein of unknown function (DUF1351)
GHKNIELH_01750 3.9e-09
GHKNIELH_01758 2.9e-34
GHKNIELH_01759 2.3e-12 K BRO family, N-terminal domain
GHKNIELH_01760 2.7e-41 S ORF6C domain
GHKNIELH_01762 4.1e-13 cI K Helix-turn-helix XRE-family like proteins
GHKNIELH_01769 2.8e-14 L Belongs to the 'phage' integrase family
GHKNIELH_01770 5e-128 L Belongs to the 'phage' integrase family
GHKNIELH_01771 1e-116 dprA LU DNA protecting protein DprA
GHKNIELH_01772 7.1e-86 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHKNIELH_01773 4.7e-33 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHKNIELH_01774 1.9e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GHKNIELH_01775 1.1e-74 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
GHKNIELH_01776 9.5e-173 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
GHKNIELH_01777 4.6e-35 yozE S Belongs to the UPF0346 family
GHKNIELH_01778 1e-63 DegV S Uncharacterised protein, DegV family COG1307
GHKNIELH_01779 4.1e-31 DegV S Uncharacterised protein, DegV family COG1307
GHKNIELH_01780 2.2e-114 hlyIII S protein, hemolysin III
GHKNIELH_01781 7.8e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GHKNIELH_01782 5.5e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GHKNIELH_01783 4.2e-54 kch J Ion transport protein
GHKNIELH_01784 1.1e-119
GHKNIELH_01785 5.2e-196 S SIR2-like domain
GHKNIELH_01786 1.5e-143 N Uncharacterized conserved protein (DUF2075)
GHKNIELH_01787 5.7e-66 N Uncharacterized conserved protein (DUF2075)
GHKNIELH_01788 3.8e-120 N Uncharacterized conserved protein (DUF2075)
GHKNIELH_01789 6.7e-66 S Tetratricopeptide repeat protein
GHKNIELH_01790 6.5e-132 S Tetratricopeptide repeat protein
GHKNIELH_01791 6.1e-23 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GHKNIELH_01792 1.3e-243 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GHKNIELH_01793 6e-219 rpsA 1.17.7.4 J Ribosomal protein S1
GHKNIELH_01794 8.2e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GHKNIELH_01795 6.4e-97 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GHKNIELH_01796 7.2e-20 M Lysin motif
GHKNIELH_01797 2.4e-32 M Lysin motif
GHKNIELH_01798 5.4e-59 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GHKNIELH_01799 9.4e-56 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GHKNIELH_01800 8.5e-90 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GHKNIELH_01801 6.3e-134 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GHKNIELH_01802 1.8e-62 ribT K acetyltransferase
GHKNIELH_01803 1.7e-165 xerD D recombinase XerD
GHKNIELH_01804 1.9e-86 cvfB S S1 domain
GHKNIELH_01805 6.3e-70 cvfB S S1 domain
GHKNIELH_01806 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GHKNIELH_01807 3e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GHKNIELH_01808 0.0 dnaE 2.7.7.7 L DNA polymerase
GHKNIELH_01809 8.1e-158 dnaE 2.7.7.7 L DNA polymerase
GHKNIELH_01810 2e-26 S Protein of unknown function (DUF2929)
GHKNIELH_01811 6.5e-306 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
GHKNIELH_01812 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GHKNIELH_01813 3.4e-47 yrvD S Lipopolysaccharide assembly protein A domain
GHKNIELH_01814 3.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GHKNIELH_01815 2e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GHKNIELH_01816 0.0 oatA I Acyltransferase
GHKNIELH_01817 2.7e-241 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GHKNIELH_01818 1.4e-34 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GHKNIELH_01819 1.3e-303 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GHKNIELH_01820 9.1e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
GHKNIELH_01821 1.7e-89 dedA 3.1.3.1 S SNARE associated Golgi protein
GHKNIELH_01822 4.1e-110 xerD L Phage integrase, N-terminal SAM-like domain
GHKNIELH_01823 1.8e-116 GM NmrA-like family
GHKNIELH_01824 1.1e-245 yagE E amino acid
GHKNIELH_01825 1.6e-94 S Rib/alpha-like repeat
GHKNIELH_01826 6.6e-63 S Domain of unknown function DUF1828
GHKNIELH_01827 2.3e-66
GHKNIELH_01828 2.1e-32
GHKNIELH_01829 1.7e-78 mutT 3.6.1.55 F NUDIX domain
GHKNIELH_01830 2.4e-57
GHKNIELH_01832 7.4e-150 htpX O Peptidase family M48
GHKNIELH_01833 2.8e-37 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
GHKNIELH_01834 3.1e-96 3.6.4.12 L ATP-dependent DNA helicase activity
GHKNIELH_01835 7.8e-46 3.6.4.12 L ATP-dependent DNA helicase activity
GHKNIELH_01836 1.3e-53 L AAA ATPase domain
GHKNIELH_01837 8.6e-50 L AAA ATPase domain
GHKNIELH_01838 1.2e-56 L AAA ATPase domain
GHKNIELH_01839 4.1e-189 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GHKNIELH_01840 9.7e-117 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GHKNIELH_01841 3.3e-166 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GHKNIELH_01842 2.7e-207 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GHKNIELH_01843 2.4e-174 KQ helix_turn_helix, mercury resistance
GHKNIELH_01844 2e-43 S KAP family P-loop domain
GHKNIELH_01845 4.2e-62 yugI 5.3.1.9 J general stress protein
GHKNIELH_01846 5.3e-51 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
GHKNIELH_01847 2.5e-52 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
GHKNIELH_01848 2.7e-117 dedA S SNARE-like domain protein
GHKNIELH_01849 1.5e-104 S Protein of unknown function (DUF1461)
GHKNIELH_01850 1.2e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GHKNIELH_01851 9.3e-95 yutD S Protein of unknown function (DUF1027)
GHKNIELH_01852 1.4e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
GHKNIELH_01853 3.3e-55
GHKNIELH_01854 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GHKNIELH_01855 4e-275 pepV 3.5.1.18 E dipeptidase PepV
GHKNIELH_01856 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
GHKNIELH_01857 9.8e-175 ccpA K catabolite control protein A
GHKNIELH_01858 5.5e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GHKNIELH_01859 8.1e-49
GHKNIELH_01860 1.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GHKNIELH_01861 6e-139 ykuT M mechanosensitive ion channel
GHKNIELH_01862 3.6e-216 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHKNIELH_01863 0.0 UW LPXTG-motif cell wall anchor domain protein
GHKNIELH_01864 1.5e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GHKNIELH_01865 2.5e-144 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GHKNIELH_01866 1.3e-12 yslB S Protein of unknown function (DUF2507)
GHKNIELH_01867 5.6e-33 yslB S Protein of unknown function (DUF2507)
GHKNIELH_01868 1.1e-52 trxA O Belongs to the thioredoxin family
GHKNIELH_01869 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GHKNIELH_01870 3.9e-93 cvpA S Colicin V production protein
GHKNIELH_01871 4.2e-39 yrzB S Belongs to the UPF0473 family
GHKNIELH_01872 8.8e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GHKNIELH_01873 2.6e-42 yrzL S Belongs to the UPF0297 family
GHKNIELH_01874 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GHKNIELH_01875 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GHKNIELH_01876 1.9e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
GHKNIELH_01877 2e-197 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GHKNIELH_01878 4.2e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GHKNIELH_01879 1.3e-38 yajC U Preprotein translocase
GHKNIELH_01880 4.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GHKNIELH_01881 7.9e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GHKNIELH_01882 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GHKNIELH_01883 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GHKNIELH_01884 0.0 nisT V ABC transporter
GHKNIELH_01885 7.5e-112
GHKNIELH_01886 1.8e-295 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GHKNIELH_01887 2e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GHKNIELH_01889 4e-120 liaI S membrane
GHKNIELH_01890 2.7e-79 XK27_02470 K LytTr DNA-binding domain
GHKNIELH_01891 7e-47 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
GHKNIELH_01892 4.8e-102 yvdD 3.2.2.10 S Belongs to the LOG family
GHKNIELH_01893 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GHKNIELH_01894 0.0 uup S ABC transporter, ATP-binding protein
GHKNIELH_01895 1.4e-242 G Bacterial extracellular solute-binding protein
GHKNIELH_01896 2.1e-82
GHKNIELH_01897 1.2e-149 K Helix-turn-helix XRE-family like proteins
GHKNIELH_01898 1.2e-115 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GHKNIELH_01899 1.3e-137 K LytTr DNA-binding domain
GHKNIELH_01900 2.1e-73 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GHKNIELH_01901 8.1e-20 yphH S Cupin domain
GHKNIELH_01902 1.3e-40 yphH S Cupin domain
GHKNIELH_01903 8.7e-120 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
GHKNIELH_01904 7.7e-92 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
GHKNIELH_01905 9.5e-242 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
GHKNIELH_01906 1.1e-30 K helix_turn_helix multiple antibiotic resistance protein
GHKNIELH_01907 2.8e-266 lmrA 3.6.3.44 V ABC transporter
GHKNIELH_01908 4e-79 C Aldo keto reductase
GHKNIELH_01909 1.7e-44 C Aldo keto reductase
GHKNIELH_01910 2.1e-14 K Transcriptional regulator
GHKNIELH_01911 1.9e-186 yrvN L AAA C-terminal domain
GHKNIELH_01912 5.1e-170 4.1.1.45 S Amidohydrolase
GHKNIELH_01913 1.4e-31
GHKNIELH_01914 4e-53 ybhL S Belongs to the BI1 family
GHKNIELH_01915 3.4e-172
GHKNIELH_01916 2.5e-35 S ABC-2 family transporter protein
GHKNIELH_01917 8.8e-69 S ABC-2 family transporter protein
GHKNIELH_01918 1.2e-155 V ATPases associated with a variety of cellular activities
GHKNIELH_01919 2.5e-166 akr5f 1.1.1.346 S reductase
GHKNIELH_01920 2.6e-95 lacA 2.3.1.79 S Transferase hexapeptide repeat
GHKNIELH_01921 4.9e-114 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GHKNIELH_01922 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GHKNIELH_01923 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GHKNIELH_01924 8.2e-179 K Transcriptional regulator
GHKNIELH_01925 3.3e-75 ppaC 3.6.1.1 C inorganic pyrophosphatase
GHKNIELH_01926 4.9e-85 ppaC 3.6.1.1 C inorganic pyrophosphatase
GHKNIELH_01927 1.5e-34 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
GHKNIELH_01928 4.2e-118 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
GHKNIELH_01929 1.8e-99 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
GHKNIELH_01930 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GHKNIELH_01931 1.7e-54 yoaK S Protein of unknown function (DUF1275)
GHKNIELH_01932 5.2e-51 yoaK S Protein of unknown function (DUF1275)
GHKNIELH_01933 9.2e-203 xerS L Belongs to the 'phage' integrase family
GHKNIELH_01934 1e-08 K Transcriptional regulator
GHKNIELH_01935 5.4e-128 K Transcriptional regulator
GHKNIELH_01936 5e-151
GHKNIELH_01937 2.2e-162 degV S EDD domain protein, DegV family
GHKNIELH_01938 2.2e-16
GHKNIELH_01939 2e-62 FbpA K Fibronectin-binding protein
GHKNIELH_01940 8.8e-176 FbpA K Fibronectin-binding protein
GHKNIELH_01941 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
GHKNIELH_01942 5.1e-41 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
GHKNIELH_01943 2e-43 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
GHKNIELH_01944 5.3e-195 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GHKNIELH_01945 6.1e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GHKNIELH_01946 3.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GHKNIELH_01947 9.7e-247 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GHKNIELH_01948 3.3e-35 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GHKNIELH_01949 7.8e-55
GHKNIELH_01950 1.7e-173 degV S DegV family
GHKNIELH_01951 3.7e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
GHKNIELH_01952 2e-241 cpdA S Calcineurin-like phosphoesterase
GHKNIELH_01953 2.2e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GHKNIELH_01954 2.1e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GHKNIELH_01955 9.7e-103 ypsA S Belongs to the UPF0398 family
GHKNIELH_01956 8.2e-31 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GHKNIELH_01957 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GHKNIELH_01958 1.8e-63 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GHKNIELH_01959 1.8e-113 dnaD L DnaD domain protein
GHKNIELH_01960 4.8e-56 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
GHKNIELH_01961 7.6e-27 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
GHKNIELH_01962 4.5e-129 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
GHKNIELH_01963 1.9e-48 ypmB S Protein conserved in bacteria
GHKNIELH_01964 7.2e-18 ypmB S Protein conserved in bacteria
GHKNIELH_01965 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GHKNIELH_01966 5.4e-104 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GHKNIELH_01967 5.4e-220 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GHKNIELH_01969 2.5e-81 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GHKNIELH_01970 5.1e-145 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GHKNIELH_01971 5.6e-37 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GHKNIELH_01972 8.7e-30 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GHKNIELH_01973 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GHKNIELH_01974 2e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
GHKNIELH_01975 1.6e-65 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GHKNIELH_01976 7.8e-100 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GHKNIELH_01977 4.5e-84 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GHKNIELH_01978 7.1e-74 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GHKNIELH_01979 7.3e-71 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GHKNIELH_01980 7e-11 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GHKNIELH_01981 6.5e-43 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GHKNIELH_01982 1.7e-35 V ABC-type multidrug transport system, ATPase and permease components
GHKNIELH_01983 1.1e-210 V ABC-type multidrug transport system, ATPase and permease components
GHKNIELH_01984 2.2e-279 V ABC-type multidrug transport system, ATPase and permease components
GHKNIELH_01985 2.1e-43 G Transmembrane secretion effector
GHKNIELH_01986 4.9e-129 G Transmembrane secretion effector
GHKNIELH_01987 7.2e-135 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
GHKNIELH_01988 1.3e-128 rbsU U ribose uptake protein RbsU
GHKNIELH_01989 5.2e-16 rbsU U ribose uptake protein RbsU
GHKNIELH_01990 5.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GHKNIELH_01991 3.4e-71 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GHKNIELH_01992 2.7e-70 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GHKNIELH_01993 3.5e-71 6.3.3.2 S ASCH
GHKNIELH_01994 1.9e-26 2.4.2.3 F Phosphorylase superfamily
GHKNIELH_01995 4.7e-114 2.4.2.3 F Phosphorylase superfamily
GHKNIELH_01996 9.2e-144 2.4.2.3 F Phosphorylase superfamily
GHKNIELH_01997 1.3e-115 2.4.2.3 F Phosphorylase superfamily
GHKNIELH_01998 7e-83 3.6.1.55 F NUDIX domain
GHKNIELH_01999 7.4e-19 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GHKNIELH_02000 1.1e-79
GHKNIELH_02001 1.2e-95
GHKNIELH_02002 7.6e-54 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
GHKNIELH_02003 2.6e-43 S Alpha/beta hydrolase family
GHKNIELH_02004 8.4e-15 S Alpha/beta hydrolase family
GHKNIELH_02005 9.4e-86 XK27_07525 3.6.1.55 F NUDIX domain
GHKNIELH_02006 1.1e-65 2.3.1.57 K Acetyltransferase (GNAT) family
GHKNIELH_02007 1.3e-88 rimL J Acetyltransferase (GNAT) domain
GHKNIELH_02008 5.4e-96 aroD S Serine hydrolase (FSH1)
GHKNIELH_02009 4.8e-228 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHKNIELH_02010 1.8e-23 UW Tetratricopeptide repeat
GHKNIELH_02011 3.6e-29 cpsJ S glycosyl transferase family 2
GHKNIELH_02012 2.2e-119 cpsJ S glycosyl transferase family 2
GHKNIELH_02013 2e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
GHKNIELH_02014 1.9e-159 3.5.2.6 V Beta-lactamase enzyme family
GHKNIELH_02015 1.1e-95 yobS K Bacterial regulatory proteins, tetR family
GHKNIELH_02016 0.0 ydgH S MMPL family
GHKNIELH_02017 1.3e-145 cof S haloacid dehalogenase-like hydrolase
GHKNIELH_02018 5.8e-126 S SNARE associated Golgi protein
GHKNIELH_02019 1.6e-177
GHKNIELH_02020 7.2e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
GHKNIELH_02021 3.3e-155 hipB K Helix-turn-helix
GHKNIELH_02022 6.3e-156 I alpha/beta hydrolase fold
GHKNIELH_02023 5.3e-107 yjbF S SNARE associated Golgi protein
GHKNIELH_02024 2.3e-101 J Acetyltransferase (GNAT) domain
GHKNIELH_02025 2.2e-153 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GHKNIELH_02026 1.2e-45 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)