ORF_ID e_value Gene_name EC_number CAZy COGs Description
HEFMEDGA_00001 3.3e-280 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEFMEDGA_00002 1.9e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEFMEDGA_00003 8.4e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEFMEDGA_00004 1.2e-82 S Protein of unknown function (DUF721)
HEFMEDGA_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEFMEDGA_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEFMEDGA_00007 8.4e-51 S Transmembrane domain of unknown function (DUF3566)
HEFMEDGA_00008 1.5e-183 lacR K Transcriptional regulator, LacI family
HEFMEDGA_00009 6.6e-15 lacS G Psort location CytoplasmicMembrane, score 10.00
HEFMEDGA_00010 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HEFMEDGA_00011 1.1e-206 V VanZ like family
HEFMEDGA_00013 4.3e-258 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEFMEDGA_00014 5.3e-197 S Psort location CytoplasmicMembrane, score
HEFMEDGA_00017 1.3e-122 S Protein of unknown function DUF45
HEFMEDGA_00019 3.6e-257 S Domain of unknown function (DUF4143)
HEFMEDGA_00020 3.3e-83 dps P Belongs to the Dps family
HEFMEDGA_00021 7.2e-117 L Transposase and inactivated derivatives IS30 family
HEFMEDGA_00022 1.1e-88 amyE G Bacterial extracellular solute-binding protein
HEFMEDGA_00023 1e-114 S Protein of unknown function, DUF624
HEFMEDGA_00024 3.8e-201 K Periplasmic binding protein domain
HEFMEDGA_00025 2.1e-292 3.2.1.26 GH32 G Glycosyl hydrolases family 32
HEFMEDGA_00026 1e-251 amyE G Bacterial extracellular solute-binding protein
HEFMEDGA_00027 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HEFMEDGA_00028 3e-187 K Psort location Cytoplasmic, score
HEFMEDGA_00029 1.3e-212 L Transposase and inactivated derivatives IS30 family
HEFMEDGA_00030 1e-147 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HEFMEDGA_00031 4.1e-52 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HEFMEDGA_00032 7e-75 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HEFMEDGA_00033 5.8e-152 rafG G ABC transporter permease
HEFMEDGA_00034 4.2e-150 malC G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00035 1.5e-30 K Psort location Cytoplasmic, score
HEFMEDGA_00036 6.9e-72 K Psort location Cytoplasmic, score
HEFMEDGA_00037 2e-76 amyE G Bacterial extracellular solute-binding protein
HEFMEDGA_00038 1.1e-115 amyE G Bacterial extracellular solute-binding protein
HEFMEDGA_00040 5.9e-229 M Protein of unknown function (DUF2961)
HEFMEDGA_00041 3e-254 amyE G Bacterial extracellular solute-binding protein
HEFMEDGA_00042 8.9e-187 K Periplasmic binding protein-like domain
HEFMEDGA_00043 1.2e-266 amyE G Bacterial extracellular solute-binding protein
HEFMEDGA_00044 5.6e-83 dps P Belongs to the Dps family
HEFMEDGA_00045 2.7e-236 ytfL P Transporter associated domain
HEFMEDGA_00046 3.8e-207 S AAA ATPase domain
HEFMEDGA_00047 2.8e-120 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HEFMEDGA_00048 1e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HEFMEDGA_00049 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HEFMEDGA_00050 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
HEFMEDGA_00051 1.2e-163
HEFMEDGA_00052 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
HEFMEDGA_00053 3.8e-281 pelF GT4 M Domain of unknown function (DUF3492)
HEFMEDGA_00054 1.7e-282 pelG S Putative exopolysaccharide Exporter (EPS-E)
HEFMEDGA_00055 0.0 cotH M CotH kinase protein
HEFMEDGA_00056 4.1e-158 P VTC domain
HEFMEDGA_00057 8.5e-111 S Domain of unknown function (DUF4956)
HEFMEDGA_00058 0.0 yliE T Putative diguanylate phosphodiesterase
HEFMEDGA_00059 1.9e-81 S AAA domain
HEFMEDGA_00060 2.3e-32 K helix_turn _helix lactose operon repressor
HEFMEDGA_00061 1.7e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HEFMEDGA_00063 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HEFMEDGA_00064 0.0 yjjP S Threonine/Serine exporter, ThrE
HEFMEDGA_00065 3.6e-299 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEFMEDGA_00066 4.9e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HEFMEDGA_00067 1.9e-305 S Amidohydrolase family
HEFMEDGA_00068 5.5e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEFMEDGA_00069 4e-34 S Protein of unknown function (DUF3073)
HEFMEDGA_00070 7.1e-71 I Sterol carrier protein
HEFMEDGA_00071 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEFMEDGA_00072 2.6e-35
HEFMEDGA_00073 7.9e-121 gluP 3.4.21.105 S Rhomboid family
HEFMEDGA_00074 2.6e-69 crgA D Involved in cell division
HEFMEDGA_00075 1.8e-118 S Bacterial protein of unknown function (DUF881)
HEFMEDGA_00076 2.8e-224 srtA 3.4.22.70 M Sortase family
HEFMEDGA_00077 2e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HEFMEDGA_00078 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
HEFMEDGA_00079 1e-173 T Protein tyrosine kinase
HEFMEDGA_00080 6.3e-263 pbpA M penicillin-binding protein
HEFMEDGA_00081 1.5e-278 rodA D Belongs to the SEDS family
HEFMEDGA_00082 1.8e-271 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HEFMEDGA_00083 1e-74 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HEFMEDGA_00084 2e-129 fhaA T Protein of unknown function (DUF2662)
HEFMEDGA_00085 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HEFMEDGA_00086 5.8e-213 pldB 3.1.1.5 I Serine aminopeptidase, S33
HEFMEDGA_00087 3.4e-91 hsp20 O Hsp20/alpha crystallin family
HEFMEDGA_00088 3.2e-178 yddG EG EamA-like transporter family
HEFMEDGA_00089 1.3e-23
HEFMEDGA_00090 1.2e-255 S Putative esterase
HEFMEDGA_00091 0.0 lysX S Uncharacterised conserved protein (DUF2156)
HEFMEDGA_00092 9e-200 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEFMEDGA_00093 5.7e-132 S Pyridoxamine 5'-phosphate oxidase
HEFMEDGA_00094 5.2e-198 S Fic/DOC family
HEFMEDGA_00095 4.1e-163 M Glycosyltransferase like family 2
HEFMEDGA_00096 1.4e-305 KL Domain of unknown function (DUF3427)
HEFMEDGA_00097 0.0 KL Domain of unknown function (DUF3427)
HEFMEDGA_00098 1.8e-74 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HEFMEDGA_00099 3.5e-52 ybjQ S Putative heavy-metal-binding
HEFMEDGA_00100 5.3e-145 yplQ S Haemolysin-III related
HEFMEDGA_00102 6.3e-262 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEFMEDGA_00103 4.1e-262 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HEFMEDGA_00104 0.0 cadA P E1-E2 ATPase
HEFMEDGA_00105 1.8e-278 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HEFMEDGA_00106 1.5e-172 htpX O Belongs to the peptidase M48B family
HEFMEDGA_00108 1.4e-148 yicL EG EamA-like transporter family
HEFMEDGA_00109 2.3e-198 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HEFMEDGA_00110 3.1e-245 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEFMEDGA_00111 3.1e-281 clcA P Voltage gated chloride channel
HEFMEDGA_00112 1e-134 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEFMEDGA_00113 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEFMEDGA_00114 1.6e-202 K helix_turn _helix lactose operon repressor
HEFMEDGA_00116 6.1e-301 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HEFMEDGA_00117 5.4e-279 scrT G Transporter major facilitator family protein
HEFMEDGA_00118 1.4e-179 K helix_turn _helix lactose operon repressor
HEFMEDGA_00119 3.8e-254 yhjE EGP Sugar (and other) transporter
HEFMEDGA_00120 2.4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEFMEDGA_00121 6.6e-187 K Periplasmic binding protein domain
HEFMEDGA_00122 5.5e-15 G Bacterial extracellular solute-binding protein
HEFMEDGA_00123 6.4e-229 G Bacterial extracellular solute-binding protein
HEFMEDGA_00124 6.9e-209 malC P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00125 3.4e-169 P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00126 2.8e-284 bglA 3.2.1.21 G Glycosyl hydrolase family 1
HEFMEDGA_00127 3.7e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEFMEDGA_00128 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HEFMEDGA_00129 1.4e-187 K Psort location Cytoplasmic, score
HEFMEDGA_00130 0.0 M cell wall anchor domain protein
HEFMEDGA_00131 0.0 M domain protein
HEFMEDGA_00132 3.6e-174 3.4.22.70 M Sortase family
HEFMEDGA_00133 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HEFMEDGA_00134 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
HEFMEDGA_00135 6.8e-234 malE G Bacterial extracellular solute-binding protein
HEFMEDGA_00136 5.1e-254 malF G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00137 1.2e-166 malG G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00138 1.9e-144 traX S TraX protein
HEFMEDGA_00139 1.1e-194 K Psort location Cytoplasmic, score
HEFMEDGA_00140 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
HEFMEDGA_00141 0.0 dnaK O Heat shock 70 kDa protein
HEFMEDGA_00142 1.5e-57 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEFMEDGA_00143 9.4e-157 dnaJ1 O DnaJ molecular chaperone homology domain
HEFMEDGA_00144 1.2e-103 hspR K transcriptional regulator, MerR family
HEFMEDGA_00145 3.1e-17 F Psort location CytoplasmicMembrane, score 10.00
HEFMEDGA_00146 5.1e-115 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
HEFMEDGA_00147 2.8e-140 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HEFMEDGA_00148 8.8e-127 S HAD hydrolase, family IA, variant 3
HEFMEDGA_00149 1.6e-134 dedA S SNARE associated Golgi protein
HEFMEDGA_00150 2.9e-124 cpaE D bacterial-type flagellum organization
HEFMEDGA_00151 5e-190 cpaF U Type II IV secretion system protein
HEFMEDGA_00152 2.6e-74 U Type ii secretion system
HEFMEDGA_00153 2.6e-115 gspF NU Type II secretion system (T2SS), protein F
HEFMEDGA_00154 1.1e-41 S Protein of unknown function (DUF4244)
HEFMEDGA_00155 1.4e-57 U TadE-like protein
HEFMEDGA_00156 6.5e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
HEFMEDGA_00157 4.5e-216 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
HEFMEDGA_00158 6.5e-97 K Bacterial regulatory proteins, tetR family
HEFMEDGA_00159 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HEFMEDGA_00160 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEFMEDGA_00161 1.8e-199 3.4.22.70 M Sortase family
HEFMEDGA_00162 1.8e-68 V Abi-like protein
HEFMEDGA_00163 1.9e-106 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HEFMEDGA_00164 8.4e-72 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HEFMEDGA_00165 1.3e-134 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HEFMEDGA_00166 9.4e-98 askB 1.1.1.3, 2.7.2.4 E ACT domain
HEFMEDGA_00167 2.6e-213 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEFMEDGA_00168 9.6e-112
HEFMEDGA_00169 2.4e-172 L Domain of unknown function (DUF4862)
HEFMEDGA_00170 1.1e-168 2.7.1.2 GK ROK family
HEFMEDGA_00171 2.8e-125 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HEFMEDGA_00172 3.3e-160 3.5.1.106 I carboxylic ester hydrolase activity
HEFMEDGA_00173 2.1e-285 E Bacterial extracellular solute-binding proteins, family 5 Middle
HEFMEDGA_00174 4.6e-153 oppB6 EP Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00175 0.0 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
HEFMEDGA_00176 1.7e-148 oppF E ATPases associated with a variety of cellular activities
HEFMEDGA_00177 2e-180 nanL 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
HEFMEDGA_00178 3.7e-148 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEFMEDGA_00179 2.7e-13 nagA 3.5.1.25 G Amidohydrolase family
HEFMEDGA_00180 0.0 nanI 3.2.1.18 GH33 G BNR repeat-like domain
HEFMEDGA_00181 4.1e-242 P Domain of unknown function (DUF4143)
HEFMEDGA_00182 5e-151 K FCD
HEFMEDGA_00183 3.3e-15 S Calcineurin-like phosphoesterase
HEFMEDGA_00184 1.7e-268 S Calcineurin-like phosphoesterase
HEFMEDGA_00185 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEFMEDGA_00186 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HEFMEDGA_00187 2.4e-169 3.6.1.27 I PAP2 superfamily
HEFMEDGA_00188 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEFMEDGA_00189 1.6e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEFMEDGA_00190 7.8e-208 holB 2.7.7.7 L DNA polymerase III
HEFMEDGA_00191 2.3e-105 K helix_turn _helix lactose operon repressor
HEFMEDGA_00192 3.3e-37 ptsH G PTS HPr component phosphorylation site
HEFMEDGA_00194 7.8e-294 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEFMEDGA_00195 6.5e-31 3.4.17.14 M domain, Protein
HEFMEDGA_00196 3e-19 D nuclear chromosome segregation
HEFMEDGA_00197 2.5e-106 S Phosphatidylethanolamine-binding protein
HEFMEDGA_00198 0.0 pepD E Peptidase family C69
HEFMEDGA_00199 1.8e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HEFMEDGA_00200 3.3e-61 S Macrophage migration inhibitory factor (MIF)
HEFMEDGA_00201 8.4e-96 S GtrA-like protein
HEFMEDGA_00202 9.7e-248 EGP Major facilitator Superfamily
HEFMEDGA_00203 1.7e-122 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HEFMEDGA_00204 1.4e-117
HEFMEDGA_00205 1.2e-227 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HEFMEDGA_00206 1.5e-157 S Protein of unknown function (DUF805)
HEFMEDGA_00208 1e-292 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEFMEDGA_00211 4.7e-69
HEFMEDGA_00212 2.5e-134 yoaK S Protein of unknown function (DUF1275)
HEFMEDGA_00213 2e-55 ydeP K HxlR-like helix-turn-helix
HEFMEDGA_00214 1.2e-79 XK27_10430 S NAD(P)H-binding
HEFMEDGA_00215 6.8e-306 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HEFMEDGA_00216 1.2e-264 EGP Major Facilitator Superfamily
HEFMEDGA_00217 0.0 1.3.3.6, 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
HEFMEDGA_00218 0.0 H Beta-ketoacyl synthase, C-terminal domain
HEFMEDGA_00219 2.8e-114 K WHG domain
HEFMEDGA_00220 2.5e-110 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
HEFMEDGA_00221 2.6e-91
HEFMEDGA_00222 2e-166
HEFMEDGA_00223 5.4e-152 L HNH endonuclease
HEFMEDGA_00225 6.2e-46 L Transposase
HEFMEDGA_00226 9.6e-136 tnp7109-21 L Integrase core domain
HEFMEDGA_00227 1.7e-173 S Domain of unknown function (DUF4928)
HEFMEDGA_00228 6.7e-231 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HEFMEDGA_00229 9.3e-283 S FRG domain
HEFMEDGA_00230 0.0 T AAA domain
HEFMEDGA_00231 1.8e-27
HEFMEDGA_00232 4.1e-282 L Phage integrase, N-terminal SAM-like domain
HEFMEDGA_00234 0.0 efeU_1 P Iron permease FTR1 family
HEFMEDGA_00235 2.8e-99 tpd P Fe2+ transport protein
HEFMEDGA_00236 7.7e-233 S Predicted membrane protein (DUF2318)
HEFMEDGA_00237 7e-221 macB_2 V ABC transporter permease
HEFMEDGA_00238 2.1e-199 Z012_06715 V FtsX-like permease family
HEFMEDGA_00239 4.5e-146 macB V ABC transporter, ATP-binding protein
HEFMEDGA_00240 1.7e-67 S FMN_bind
HEFMEDGA_00241 9.2e-101 K Psort location Cytoplasmic, score 8.87
HEFMEDGA_00242 3.4e-305 pip S YhgE Pip domain protein
HEFMEDGA_00243 0.0 pip S YhgE Pip domain protein
HEFMEDGA_00244 2.5e-253 S Putative ABC-transporter type IV
HEFMEDGA_00245 1.5e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEFMEDGA_00246 1.3e-140 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HEFMEDGA_00247 4.1e-192 opcA G Glucose-6-phosphate dehydrogenase subunit
HEFMEDGA_00248 4.5e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEFMEDGA_00249 3.4e-290 3.5.2.6 V Beta-lactamase enzyme family
HEFMEDGA_00251 6.5e-298 pepD E Peptidase family C69
HEFMEDGA_00252 3.3e-197 XK27_01805 M Glycosyltransferase like family 2
HEFMEDGA_00253 1.4e-150 icaR K Bacterial regulatory proteins, tetR family
HEFMEDGA_00254 1.2e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEFMEDGA_00255 6.9e-229 amt U Ammonium Transporter Family
HEFMEDGA_00256 1e-54 glnB K Nitrogen regulatory protein P-II
HEFMEDGA_00257 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HEFMEDGA_00258 1.6e-239 dinF V MatE
HEFMEDGA_00259 1.2e-256 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HEFMEDGA_00260 3.9e-257 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HEFMEDGA_00261 3.7e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HEFMEDGA_00262 5.5e-38 S granule-associated protein
HEFMEDGA_00263 0.0 ubiB S ABC1 family
HEFMEDGA_00264 9.3e-47 K Periplasmic binding protein domain
HEFMEDGA_00265 1.3e-305 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HEFMEDGA_00266 7e-156 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEFMEDGA_00267 1.3e-187 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEFMEDGA_00268 4.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HEFMEDGA_00269 4e-76 ssb1 L Single-stranded DNA-binding protein
HEFMEDGA_00270 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEFMEDGA_00271 2.7e-71 rplI J Binds to the 23S rRNA
HEFMEDGA_00274 8.9e-159 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
HEFMEDGA_00275 1.9e-116
HEFMEDGA_00276 3.1e-130 V ABC transporter
HEFMEDGA_00277 3.7e-111 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEFMEDGA_00278 1.4e-209 2.7.13.3 T Histidine kinase
HEFMEDGA_00279 6e-189 EGP Major Facilitator Superfamily
HEFMEDGA_00280 6.2e-43
HEFMEDGA_00281 8.6e-60
HEFMEDGA_00282 1e-127 xerH L Belongs to the 'phage' integrase family
HEFMEDGA_00283 1.9e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HEFMEDGA_00284 0.0 pacS 1.9.3.1, 3.6.3.54 P E1-E2 ATPase
HEFMEDGA_00285 3.3e-43 csoR S Metal-sensitive transcriptional repressor
HEFMEDGA_00286 1.6e-210 rmuC S RmuC family
HEFMEDGA_00287 3.7e-111 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEFMEDGA_00288 6.9e-170 spoU 2.1.1.185 J RNA methyltransferase TrmH family
HEFMEDGA_00289 6.4e-168 V ABC transporter
HEFMEDGA_00290 2.6e-178
HEFMEDGA_00291 5.6e-55 K Psort location Cytoplasmic, score
HEFMEDGA_00292 2.2e-53 K Psort location Cytoplasmic, score
HEFMEDGA_00293 2.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEFMEDGA_00294 1.2e-285 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEFMEDGA_00295 7.4e-283 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEFMEDGA_00296 1.1e-195 2.3.1.57 J Acetyltransferase (GNAT) domain
HEFMEDGA_00297 3.3e-52 S Protein of unknown function (DUF2469)
HEFMEDGA_00298 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
HEFMEDGA_00299 2.7e-293 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEFMEDGA_00300 6.9e-45 pabC 2.6.1.42, 4.1.3.38 EH Amino-transferase class IV
HEFMEDGA_00301 1.5e-71 L Transposase
HEFMEDGA_00302 5.1e-50 K helix_turn_helix, arabinose operon control protein
HEFMEDGA_00303 2.6e-154 araN G Bacterial extracellular solute-binding protein
HEFMEDGA_00304 9.5e-121 lacF P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00305 1e-114 araQ U Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00306 5.4e-131 rafA 3.2.1.22 G alpha-galactosidase
HEFMEDGA_00307 1e-63 tyrA 5.4.99.5 E Chorismate mutase type II
HEFMEDGA_00308 0.0 S domain protein
HEFMEDGA_00309 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEFMEDGA_00310 6.6e-279 E Bacterial extracellular solute-binding proteins, family 5 Middle
HEFMEDGA_00311 1.9e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEFMEDGA_00312 4e-139 KT Transcriptional regulatory protein, C terminal
HEFMEDGA_00313 2.7e-118
HEFMEDGA_00314 1.3e-97 mntP P Probably functions as a manganese efflux pump
HEFMEDGA_00315 4e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HEFMEDGA_00316 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HEFMEDGA_00317 0.0 K RNA polymerase II activating transcription factor binding
HEFMEDGA_00319 1.6e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEFMEDGA_00320 6.4e-148 atpB C it plays a direct role in the translocation of protons across the membrane
HEFMEDGA_00321 4.4e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEFMEDGA_00322 1.4e-63 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEFMEDGA_00323 1.1e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEFMEDGA_00324 1.3e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEFMEDGA_00325 5.5e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEFMEDGA_00326 2.1e-282 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEFMEDGA_00327 3.2e-49 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HEFMEDGA_00328 1.4e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HEFMEDGA_00329 9.4e-159 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HEFMEDGA_00330 4e-186
HEFMEDGA_00331 3e-179
HEFMEDGA_00332 1.7e-171 trxA2 O Tetratricopeptide repeat
HEFMEDGA_00333 7.7e-117 cyaA 4.6.1.1 S CYTH
HEFMEDGA_00336 3.6e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
HEFMEDGA_00337 8.8e-189 plsC2 2.3.1.51 I Phosphate acyltransferases
HEFMEDGA_00338 8.6e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HEFMEDGA_00339 9.1e-228 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HEFMEDGA_00340 2.2e-218 P Bacterial extracellular solute-binding protein
HEFMEDGA_00341 9.9e-161 U Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00342 5e-149 U Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00343 3.1e-237 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HEFMEDGA_00344 1.5e-186 S CAAX protease self-immunity
HEFMEDGA_00345 1.2e-135 M Mechanosensitive ion channel
HEFMEDGA_00346 8.6e-273 aspA 4.3.1.1 E Fumarase C C-terminus
HEFMEDGA_00347 2.7e-10 L Transposase DDE domain
HEFMEDGA_00348 5.4e-234 S AAA domain
HEFMEDGA_00349 1.7e-202 EGP Major Facilitator Superfamily
HEFMEDGA_00350 4.5e-54 L Transposase DDE domain
HEFMEDGA_00351 1.3e-106 K Bacterial regulatory proteins, tetR family
HEFMEDGA_00352 6.4e-254 MA20_36090 S Psort location Cytoplasmic, score 8.87
HEFMEDGA_00353 6.4e-90 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEFMEDGA_00354 2.5e-81 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEFMEDGA_00355 1e-72 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
HEFMEDGA_00356 1.1e-15 P Sodium/hydrogen exchanger family
HEFMEDGA_00359 1e-80
HEFMEDGA_00360 0.0 Q von Willebrand factor (vWF) type A domain
HEFMEDGA_00361 1.5e-278 M LPXTG cell wall anchor motif
HEFMEDGA_00362 3.8e-87
HEFMEDGA_00363 7.6e-110
HEFMEDGA_00364 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEFMEDGA_00365 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEFMEDGA_00366 2.1e-123 V ABC transporter, ATP-binding protein
HEFMEDGA_00367 4e-26 macB_7 V FtsX-like permease family
HEFMEDGA_00368 2.4e-88 lemA S LemA family
HEFMEDGA_00369 0.0 S Predicted membrane protein (DUF2207)
HEFMEDGA_00370 1.9e-10 S Predicted membrane protein (DUF2207)
HEFMEDGA_00371 1e-60 S Predicted membrane protein (DUF2207)
HEFMEDGA_00372 7.4e-21 S Predicted membrane protein (DUF2207)
HEFMEDGA_00373 7.7e-86 S Predicted membrane protein (DUF2207)
HEFMEDGA_00374 3.1e-20
HEFMEDGA_00375 2.4e-169 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HEFMEDGA_00376 2.5e-200 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HEFMEDGA_00377 2.2e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEFMEDGA_00378 1e-34 CP_0960 S Belongs to the UPF0109 family
HEFMEDGA_00379 7e-62 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HEFMEDGA_00380 8.4e-206 S Endonuclease/Exonuclease/phosphatase family
HEFMEDGA_00381 7.9e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEFMEDGA_00382 2.3e-162 P Cation efflux family
HEFMEDGA_00383 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEFMEDGA_00384 2e-136 guaA1 6.3.5.2 F Peptidase C26
HEFMEDGA_00386 1.8e-112
HEFMEDGA_00387 6.4e-103 dam 2.1.1.72 H D12 class N6 adenine-specific DNA methyltransferase
HEFMEDGA_00388 0.0 yjjK S ABC transporter
HEFMEDGA_00389 3.9e-72 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
HEFMEDGA_00390 3.9e-44 stbC S Plasmid stability protein
HEFMEDGA_00391 9e-93 ilvN 2.2.1.6 E ACT domain
HEFMEDGA_00392 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HEFMEDGA_00393 9.7e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEFMEDGA_00394 9.3e-21 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HEFMEDGA_00395 7.6e-117 yceD S Uncharacterized ACR, COG1399
HEFMEDGA_00396 7.9e-87
HEFMEDGA_00397 6e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEFMEDGA_00398 2.4e-49 S Protein of unknown function (DUF3039)
HEFMEDGA_00399 3e-195 yghZ C Aldo/keto reductase family
HEFMEDGA_00400 6.3e-78 soxR K MerR, DNA binding
HEFMEDGA_00401 3.7e-119
HEFMEDGA_00402 8e-249 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEFMEDGA_00403 7e-144 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HEFMEDGA_00404 2.2e-137 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEFMEDGA_00405 3.6e-177 S Auxin Efflux Carrier
HEFMEDGA_00408 0.0 pgi 5.3.1.9 G Belongs to the GPI family
HEFMEDGA_00409 2.1e-263 abcT3 P ATPases associated with a variety of cellular activities
HEFMEDGA_00410 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00411 1.5e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEFMEDGA_00412 3.8e-165 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HEFMEDGA_00413 1.6e-157 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEFMEDGA_00414 2.1e-210 K helix_turn _helix lactose operon repressor
HEFMEDGA_00415 2.5e-13 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HEFMEDGA_00416 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HEFMEDGA_00417 4.2e-40 araE EGP Major facilitator Superfamily
HEFMEDGA_00418 4.2e-19 araE EGP Major facilitator Superfamily
HEFMEDGA_00419 0.0 cydD V ABC transporter transmembrane region
HEFMEDGA_00420 1.6e-260 G Bacterial extracellular solute-binding protein
HEFMEDGA_00421 1.4e-101 malC G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00422 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HEFMEDGA_00423 9.7e-189 K helix_turn _helix lactose operon repressor
HEFMEDGA_00424 0.0 ganB 3.2.1.89 G Glycosyl hydrolase family 53
HEFMEDGA_00425 2e-168 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
HEFMEDGA_00426 1.6e-140 L Protein of unknown function (DUF1524)
HEFMEDGA_00427 1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
HEFMEDGA_00428 2.2e-277 EGP Major facilitator Superfamily
HEFMEDGA_00429 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
HEFMEDGA_00430 0.0 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HEFMEDGA_00431 6.3e-108 3.1.3.48 T Low molecular weight phosphatase family
HEFMEDGA_00432 7.6e-208 GT4 M Psort location Cytoplasmic, score 8.87
HEFMEDGA_00433 1.4e-245 MA20_17390 GT4 M Glycosyl transferases group 1
HEFMEDGA_00434 1.5e-253 cps2J S Polysaccharide biosynthesis protein
HEFMEDGA_00435 8.3e-201 2.4.1.166 GT2 M Glycosyltransferase like family 2
HEFMEDGA_00436 5.1e-133 H Hexapeptide repeat of succinyl-transferase
HEFMEDGA_00437 1e-212 S Polysaccharide pyruvyl transferase
HEFMEDGA_00438 5.8e-188 M Glycosyltransferase like family 2
HEFMEDGA_00440 5.9e-194 wzy S EpsG family
HEFMEDGA_00441 1.6e-191 G Acyltransferase family
HEFMEDGA_00443 1.4e-150 L IstB-like ATP binding protein
HEFMEDGA_00444 1.6e-42 L Transposase
HEFMEDGA_00445 3.6e-148 L IstB-like ATP binding protein
HEFMEDGA_00446 9.8e-296 L PFAM Integrase catalytic
HEFMEDGA_00447 3.8e-14 L Transposase
HEFMEDGA_00448 0.0 C Domain of unknown function (DUF4365)
HEFMEDGA_00449 3e-50 S Bacteriophage abortive infection AbiH
HEFMEDGA_00451 2.7e-88 K Helix-turn-helix XRE-family like proteins
HEFMEDGA_00453 2.3e-48 S enterobacterial common antigen metabolic process
HEFMEDGA_00454 3.5e-99 S enterobacterial common antigen metabolic process
HEFMEDGA_00455 1.6e-41 S Protein of unknown function (DUF3800)
HEFMEDGA_00456 3.2e-09 L Helix-turn-helix domain
HEFMEDGA_00457 5.8e-266 S Psort location CytoplasmicMembrane, score 9.99
HEFMEDGA_00458 8.3e-70
HEFMEDGA_00459 9e-246 wcoI DM Psort location CytoplasmicMembrane, score
HEFMEDGA_00460 4.7e-172
HEFMEDGA_00461 3.1e-173 S G5
HEFMEDGA_00462 1.9e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HEFMEDGA_00463 1.6e-120 F Domain of unknown function (DUF4916)
HEFMEDGA_00464 7.6e-160 mhpC I Alpha/beta hydrolase family
HEFMEDGA_00465 9.4e-215 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HEFMEDGA_00466 5.9e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HEFMEDGA_00467 5.5e-225 S Uncharacterized conserved protein (DUF2183)
HEFMEDGA_00468 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HEFMEDGA_00469 2e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEFMEDGA_00470 2.9e-218 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HEFMEDGA_00471 2.1e-134 glxR K helix_turn_helix, cAMP Regulatory protein
HEFMEDGA_00472 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HEFMEDGA_00473 3.7e-230 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
HEFMEDGA_00474 2.3e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HEFMEDGA_00475 2.8e-123 glpR K DeoR C terminal sensor domain
HEFMEDGA_00476 6.6e-253 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HEFMEDGA_00477 5.3e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HEFMEDGA_00478 6.4e-44 gcvR T Belongs to the UPF0237 family
HEFMEDGA_00479 9.4e-253 S UPF0210 protein
HEFMEDGA_00480 7.6e-115 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEFMEDGA_00481 1.1e-186 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HEFMEDGA_00482 2.3e-128
HEFMEDGA_00483 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEFMEDGA_00484 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEFMEDGA_00485 0.0 E Transglutaminase-like superfamily
HEFMEDGA_00486 6.2e-238 S Protein of unknown function DUF58
HEFMEDGA_00487 0.0 S Fibronectin type 3 domain
HEFMEDGA_00488 3e-220 KLT Protein tyrosine kinase
HEFMEDGA_00489 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HEFMEDGA_00490 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HEFMEDGA_00491 1.7e-235 G Major Facilitator Superfamily
HEFMEDGA_00492 6.4e-134 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEFMEDGA_00493 3.8e-162 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEFMEDGA_00494 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEFMEDGA_00495 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
HEFMEDGA_00496 2.6e-258 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEFMEDGA_00497 7.5e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEFMEDGA_00498 1.7e-268 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
HEFMEDGA_00499 3.5e-205 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEFMEDGA_00500 2.9e-205 ftsE D Cell division ATP-binding protein FtsE
HEFMEDGA_00501 9.8e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HEFMEDGA_00502 4e-147 usp 3.5.1.28 CBM50 D CHAP domain protein
HEFMEDGA_00503 6.3e-79 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HEFMEDGA_00504 5.6e-143 pknD ET ABC transporter, substrate-binding protein, family 3
HEFMEDGA_00505 1.1e-167 pknD ET ABC transporter, substrate-binding protein, family 3
HEFMEDGA_00506 3.6e-153 yecS E Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00507 2.2e-151 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
HEFMEDGA_00508 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEFMEDGA_00509 3.1e-141 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HEFMEDGA_00510 1.5e-186 K Periplasmic binding protein domain
HEFMEDGA_00511 5e-165 malC G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00512 4.4e-167 G ABC transporter permease
HEFMEDGA_00513 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HEFMEDGA_00514 5.1e-259 G Bacterial extracellular solute-binding protein
HEFMEDGA_00515 1.2e-277 G Bacterial extracellular solute-binding protein
HEFMEDGA_00516 5.9e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEFMEDGA_00517 2.3e-290 E ABC transporter, substrate-binding protein, family 5
HEFMEDGA_00518 1.6e-166 P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00519 1.2e-148 EP Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00520 9.3e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
HEFMEDGA_00521 1.3e-137 sapF E ATPases associated with a variety of cellular activities
HEFMEDGA_00522 1.4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HEFMEDGA_00523 1.4e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HEFMEDGA_00524 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HEFMEDGA_00525 2.7e-93 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEFMEDGA_00526 6.5e-104 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEFMEDGA_00527 6.5e-260 yhdG E aromatic amino acid transport protein AroP K03293
HEFMEDGA_00528 1.2e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEFMEDGA_00529 3.4e-244 dgt 3.1.5.1 F Phosphohydrolase-associated domain
HEFMEDGA_00530 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEFMEDGA_00531 9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HEFMEDGA_00532 1.1e-115 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HEFMEDGA_00533 2.2e-295 EK Alanine-glyoxylate amino-transferase
HEFMEDGA_00534 8.5e-210 ybiR P Citrate transporter
HEFMEDGA_00535 3.3e-30
HEFMEDGA_00537 5.6e-43 G Alpha-L-arabinofuranosidase C-terminal domain
HEFMEDGA_00538 3.9e-159 K Helix-turn-helix domain, rpiR family
HEFMEDGA_00541 7.3e-258 G Bacterial extracellular solute-binding protein
HEFMEDGA_00542 4.2e-223 K helix_turn _helix lactose operon repressor
HEFMEDGA_00543 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HEFMEDGA_00544 3.1e-14 L Psort location Cytoplasmic, score 8.87
HEFMEDGA_00545 0.0 E ABC transporter, substrate-binding protein, family 5
HEFMEDGA_00546 5.5e-86 msrA 1.8.4.11, 1.8.4.12 O peptide-methionine (S)-S-oxide reductase activity
HEFMEDGA_00547 6.2e-135 V ATPases associated with a variety of cellular activities
HEFMEDGA_00548 9.1e-181 M Conserved repeat domain
HEFMEDGA_00549 7.2e-286 macB_8 V MacB-like periplasmic core domain
HEFMEDGA_00550 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEFMEDGA_00551 4.8e-182 adh3 C Zinc-binding dehydrogenase
HEFMEDGA_00552 4.3e-86 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEFMEDGA_00553 4.2e-225 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEFMEDGA_00554 1.2e-68 zur P Belongs to the Fur family
HEFMEDGA_00555 5.7e-84 ylbB V FtsX-like permease family
HEFMEDGA_00556 2.9e-27 ylbB V FtsX-like permease family
HEFMEDGA_00557 4e-70 XK27_06785 V ABC transporter
HEFMEDGA_00558 6.1e-35
HEFMEDGA_00559 8.7e-27 zur P Ferric uptake regulator family
HEFMEDGA_00560 7.8e-140 S TIGRFAM TIGR03943 family protein
HEFMEDGA_00561 1.4e-180 ycgR S Predicted permease
HEFMEDGA_00562 2.6e-24 adcA P ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HEFMEDGA_00563 1.3e-18 J Ribosomal L32p protein family
HEFMEDGA_00564 1.1e-14 rpmJ J Ribosomal protein L36
HEFMEDGA_00565 3.7e-33 rpmE2 J Ribosomal protein L31
HEFMEDGA_00566 2.5e-44 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEFMEDGA_00567 1.4e-20 rpmG J Ribosomal protein L33
HEFMEDGA_00568 3.9e-29 rpmB J Ribosomal L28 family
HEFMEDGA_00569 1.5e-98 S cobalamin synthesis protein
HEFMEDGA_00570 7.3e-156 P Zinc-uptake complex component A periplasmic
HEFMEDGA_00571 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HEFMEDGA_00572 2.1e-296 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
HEFMEDGA_00573 7.4e-244 purD 6.3.4.13 F Belongs to the GARS family
HEFMEDGA_00574 2.1e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HEFMEDGA_00575 3.9e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEFMEDGA_00576 4.2e-300 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
HEFMEDGA_00577 3.5e-32
HEFMEDGA_00578 3.7e-12 C Aldo/keto reductase family
HEFMEDGA_00579 1.1e-102 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
HEFMEDGA_00580 2.4e-08 S Protein of unknown function (DUF4230)
HEFMEDGA_00583 1.9e-144
HEFMEDGA_00584 8.4e-114 Q D-alanine [D-alanyl carrier protein] ligase activity
HEFMEDGA_00585 8e-252 Q D-alanine [D-alanyl carrier protein] ligase activity
HEFMEDGA_00586 7.6e-239 I alpha/beta hydrolase fold
HEFMEDGA_00587 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HEFMEDGA_00588 3.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HEFMEDGA_00589 3.6e-225 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEFMEDGA_00590 4.8e-227 mtnE 2.6.1.83 E Aminotransferase class I and II
HEFMEDGA_00591 1.5e-219 M Glycosyl transferase 4-like domain
HEFMEDGA_00592 5.2e-195 ltaE 4.1.2.48 E Beta-eliminating lyase
HEFMEDGA_00594 6.6e-111 yocS S SBF-like CPA transporter family (DUF4137)
HEFMEDGA_00595 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEFMEDGA_00596 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEFMEDGA_00597 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEFMEDGA_00598 6.2e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEFMEDGA_00599 6.8e-60 tmp1 S Domain of unknown function (DUF4391)
HEFMEDGA_00600 1.3e-35 tmp1 S Domain of unknown function (DUF4391)
HEFMEDGA_00601 2.1e-146 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
HEFMEDGA_00602 2.7e-186 MA20_14895 S Conserved hypothetical protein 698
HEFMEDGA_00603 6.3e-21 S Psort location CytoplasmicMembrane, score
HEFMEDGA_00604 1.2e-28 S polysaccharide biosynthetic process
HEFMEDGA_00605 1.3e-60 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEFMEDGA_00606 8.7e-85 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEFMEDGA_00607 6.4e-67 K MerR family regulatory protein
HEFMEDGA_00608 5.6e-197 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HEFMEDGA_00609 2.3e-259 S Domain of unknown function (DUF4143)
HEFMEDGA_00610 3.4e-109 P Protein of unknown function DUF47
HEFMEDGA_00611 6.4e-170 ugpQ 3.1.4.46 C Domain of unknown function
HEFMEDGA_00612 2.6e-239 ugpB G Bacterial extracellular solute-binding protein
HEFMEDGA_00613 4e-142 ugpE G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00614 3.5e-164 ugpA P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00615 4.5e-145 P Phosphate transporter family
HEFMEDGA_00616 1.3e-190 K helix_turn _helix lactose operon repressor
HEFMEDGA_00617 1.2e-143 K LysR substrate binding domain
HEFMEDGA_00618 3.8e-101 K LysR substrate binding domain
HEFMEDGA_00619 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HEFMEDGA_00620 1.1e-242 vbsD V MatE
HEFMEDGA_00621 3.2e-124 magIII L endonuclease III
HEFMEDGA_00623 5.7e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HEFMEDGA_00624 8.7e-38 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HEFMEDGA_00625 3e-185 S Membrane transport protein
HEFMEDGA_00626 7.4e-48 4.1.1.44 L Cupin 2, conserved barrel domain protein
HEFMEDGA_00628 0.0 M probably involved in cell wall
HEFMEDGA_00629 1.2e-252 3.2.1.14 GH18 S Carbohydrate binding domain
HEFMEDGA_00630 0.0 T Diguanylate cyclase, GGDEF domain
HEFMEDGA_00631 1.1e-80 T Diguanylate cyclase, GGDEF domain
HEFMEDGA_00632 1.6e-135 ybbM V Uncharacterised protein family (UPF0014)
HEFMEDGA_00633 4.5e-129 ybbL V ATPases associated with a variety of cellular activities
HEFMEDGA_00634 3.9e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEFMEDGA_00635 1.1e-92 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEFMEDGA_00636 2e-241 carA 6.3.5.5 F Belongs to the CarA family
HEFMEDGA_00637 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HEFMEDGA_00638 6.7e-170 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HEFMEDGA_00639 1.4e-104 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HEFMEDGA_00640 3.7e-136 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HEFMEDGA_00642 0.0 tetP J Elongation factor G, domain IV
HEFMEDGA_00643 1.9e-126 ypfH S Phospholipase/Carboxylesterase
HEFMEDGA_00644 4e-234 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HEFMEDGA_00645 2.5e-42 XAC3035 O Glutaredoxin
HEFMEDGA_00646 2.7e-08 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
HEFMEDGA_00647 7.2e-116 XK27_08050 O prohibitin homologues
HEFMEDGA_00648 1.5e-25 S Domain of unknown function (DUF4143)
HEFMEDGA_00649 1.4e-15 S Domain of unknown function (DUF4143)
HEFMEDGA_00650 2.9e-159 S Patatin-like phospholipase
HEFMEDGA_00651 4.3e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HEFMEDGA_00652 7.8e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HEFMEDGA_00653 4.2e-127 S Vitamin K epoxide reductase
HEFMEDGA_00654 5.5e-169 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
HEFMEDGA_00655 4.7e-32 S Protein of unknown function (DUF3107)
HEFMEDGA_00656 5.5e-300 mphA S Aminoglycoside phosphotransferase
HEFMEDGA_00657 4e-292 uvrD2 3.6.4.12 L DNA helicase
HEFMEDGA_00658 2.1e-297 S Zincin-like metallopeptidase
HEFMEDGA_00659 1.5e-156 lon T Belongs to the peptidase S16 family
HEFMEDGA_00660 1.6e-73 S Protein of unknown function (DUF3052)
HEFMEDGA_00662 8.8e-210 2.7.11.1 NU Tfp pilus assembly protein FimV
HEFMEDGA_00663 1.7e-221 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HEFMEDGA_00664 3.5e-230 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEFMEDGA_00665 0.0 I acetylesterase activity
HEFMEDGA_00666 4.5e-129 recO L Involved in DNA repair and RecF pathway recombination
HEFMEDGA_00667 3.1e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEFMEDGA_00668 4.5e-135 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00669 6.8e-190 P NMT1/THI5 like
HEFMEDGA_00670 3.9e-226 E Aminotransferase class I and II
HEFMEDGA_00671 1.5e-141 bioM P ATPases associated with a variety of cellular activities
HEFMEDGA_00673 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEFMEDGA_00674 0.0 S Tetratricopeptide repeat
HEFMEDGA_00675 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEFMEDGA_00676 3.9e-204 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HEFMEDGA_00677 5e-281 glnA 6.3.1.2 E glutamine synthetase
HEFMEDGA_00678 1.3e-142 S Domain of unknown function (DUF4191)
HEFMEDGA_00679 4.2e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEFMEDGA_00680 6.9e-102 S Protein of unknown function (DUF3043)
HEFMEDGA_00681 1.5e-258 argE E Peptidase dimerisation domain
HEFMEDGA_00682 6.2e-108 ykoE S ABC-type cobalt transport system, permease component
HEFMEDGA_00683 1.3e-279 ykoD P ATPases associated with a variety of cellular activities
HEFMEDGA_00684 1.2e-158 cbiQ P Cobalt transport protein
HEFMEDGA_00685 1.1e-158 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEFMEDGA_00686 7.7e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEFMEDGA_00687 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HEFMEDGA_00688 1.5e-91
HEFMEDGA_00689 6.5e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEFMEDGA_00690 5.9e-211 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEFMEDGA_00691 2.2e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HEFMEDGA_00692 1.3e-248 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HEFMEDGA_00693 3.9e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEFMEDGA_00694 5.9e-83 argR K Regulates arginine biosynthesis genes
HEFMEDGA_00695 1.2e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEFMEDGA_00696 1.5e-92 L PFAM Integrase catalytic
HEFMEDGA_00697 8.5e-44 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
HEFMEDGA_00698 2.4e-32 relB L RelB antitoxin
HEFMEDGA_00699 1.2e-280 argH 4.3.2.1 E argininosuccinate lyase
HEFMEDGA_00700 1.2e-28 thiS 2.8.1.10 H ThiS family
HEFMEDGA_00701 1.4e-156 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HEFMEDGA_00702 7.8e-146 moeB 2.7.7.80 H ThiF family
HEFMEDGA_00703 3.1e-71 M1-798 P Rhodanese Homology Domain
HEFMEDGA_00704 4.6e-102 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HEFMEDGA_00705 7.4e-138 S Putative ABC-transporter type IV
HEFMEDGA_00706 5.3e-82 S Protein of unknown function (DUF975)
HEFMEDGA_00707 2.6e-255 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEFMEDGA_00708 8.5e-164 L Tetratricopeptide repeat
HEFMEDGA_00709 6e-199 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HEFMEDGA_00711 2.7e-140 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HEFMEDGA_00712 4.7e-96
HEFMEDGA_00713 1.3e-49 trkA P TrkA-N domain
HEFMEDGA_00714 1.9e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEFMEDGA_00715 0.0 recN L May be involved in recombinational repair of damaged DNA
HEFMEDGA_00716 3.6e-117 S Haloacid dehalogenase-like hydrolase
HEFMEDGA_00717 3.6e-56 J Acetyltransferase (GNAT) domain
HEFMEDGA_00718 4.8e-58 K helix_turn_helix gluconate operon transcriptional repressor
HEFMEDGA_00719 8.5e-173 V ATPases associated with a variety of cellular activities
HEFMEDGA_00720 2.9e-120 S ABC-2 family transporter protein
HEFMEDGA_00721 3.7e-107
HEFMEDGA_00722 4.2e-32 pacL2 3.6.3.8 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HEFMEDGA_00723 7.8e-71 K helix_turn_helix gluconate operon transcriptional repressor
HEFMEDGA_00724 3.1e-196 S Protein of unknown function (DUF1648)
HEFMEDGA_00725 1.5e-280 thrC 4.2.3.1 E Threonine synthase N terminus
HEFMEDGA_00726 2e-236 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEFMEDGA_00727 3e-96
HEFMEDGA_00728 3.2e-138 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEFMEDGA_00729 4.9e-142 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
HEFMEDGA_00730 0.0 S Uncharacterised protein family (UPF0182)
HEFMEDGA_00731 4.1e-93 2.3.1.183 M Acetyltransferase (GNAT) domain
HEFMEDGA_00732 1.5e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEFMEDGA_00733 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEFMEDGA_00734 5.4e-180 1.1.1.65 C Aldo/keto reductase family
HEFMEDGA_00735 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEFMEDGA_00736 6.6e-70 divIC D Septum formation initiator
HEFMEDGA_00737 8.2e-102 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HEFMEDGA_00738 5.8e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HEFMEDGA_00740 1.7e-94
HEFMEDGA_00741 1.2e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HEFMEDGA_00742 1.4e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HEFMEDGA_00743 4.4e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEFMEDGA_00744 3.1e-146 yplQ S Haemolysin-III related
HEFMEDGA_00745 1.1e-278 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HEFMEDGA_00746 4.9e-47 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HEFMEDGA_00747 0.0 D FtsK/SpoIIIE family
HEFMEDGA_00748 1.3e-206 K Cell envelope-related transcriptional attenuator domain
HEFMEDGA_00749 1.8e-55 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HEFMEDGA_00750 0.0 S Glycosyl transferase, family 2
HEFMEDGA_00751 2.3e-263
HEFMEDGA_00752 6.3e-78 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HEFMEDGA_00753 2.2e-148 cof 5.2.1.8 T Eukaryotic phosphomannomutase
HEFMEDGA_00754 1.4e-121 ctsW S Phosphoribosyl transferase domain
HEFMEDGA_00755 4.4e-197 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HEFMEDGA_00756 2.9e-128 T Response regulator receiver domain protein
HEFMEDGA_00757 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEFMEDGA_00758 2.1e-100 carD K CarD-like/TRCF domain
HEFMEDGA_00759 3.4e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HEFMEDGA_00760 2e-136 znuB U ABC 3 transport family
HEFMEDGA_00761 3.8e-162 znuC P ATPases associated with a variety of cellular activities
HEFMEDGA_00762 6.1e-184 P Zinc-uptake complex component A periplasmic
HEFMEDGA_00763 5.8e-163 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEFMEDGA_00764 3.2e-254 rpsA J Ribosomal protein S1
HEFMEDGA_00765 2.5e-114 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEFMEDGA_00766 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEFMEDGA_00767 1e-176 terC P Integral membrane protein, TerC family
HEFMEDGA_00768 2.7e-274 pyk 2.7.1.40 G Pyruvate kinase
HEFMEDGA_00769 7.4e-109 aspA 3.6.1.13 L NUDIX domain
HEFMEDGA_00771 2.8e-124 pdtaR T Response regulator receiver domain protein
HEFMEDGA_00772 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEFMEDGA_00773 5.1e-178 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HEFMEDGA_00774 4e-127 3.6.1.13 L NUDIX domain
HEFMEDGA_00775 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HEFMEDGA_00776 1.4e-24 zntR K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HEFMEDGA_00777 4e-89 K Putative zinc ribbon domain
HEFMEDGA_00778 3e-124 S GyrI-like small molecule binding domain
HEFMEDGA_00780 1.2e-20 tag 3.2.2.20 L Methyladenine glycosylase
HEFMEDGA_00782 5.4e-104 L Resolvase, N terminal domain
HEFMEDGA_00783 3.9e-187 L Helix-turn-helix domain
HEFMEDGA_00784 1.8e-107
HEFMEDGA_00785 1.9e-214 ykiI
HEFMEDGA_00786 4.6e-252 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEFMEDGA_00787 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEFMEDGA_00788 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HEFMEDGA_00790 1.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEFMEDGA_00791 0.0 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
HEFMEDGA_00792 1.3e-301 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HEFMEDGA_00793 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HEFMEDGA_00794 1.3e-262 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEFMEDGA_00795 1.1e-65 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEFMEDGA_00796 2.7e-134 3.1.3.85 G Phosphoglycerate mutase family
HEFMEDGA_00799 1.6e-157 S Sucrose-6F-phosphate phosphohydrolase
HEFMEDGA_00800 1.6e-177 metQ P NLPA lipoprotein
HEFMEDGA_00801 3.2e-220 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEFMEDGA_00802 7.4e-113 metI P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00803 5.4e-225 S Peptidase dimerisation domain
HEFMEDGA_00804 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HEFMEDGA_00805 2.6e-38
HEFMEDGA_00806 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HEFMEDGA_00807 8.7e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEFMEDGA_00808 9.8e-120 S Protein of unknown function (DUF3000)
HEFMEDGA_00809 9.9e-252 rnd 3.1.13.5 J 3'-5' exonuclease
HEFMEDGA_00810 4.4e-234 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEFMEDGA_00811 2.6e-242 clcA_2 P Voltage gated chloride channel
HEFMEDGA_00812 2.6e-59
HEFMEDGA_00813 6.5e-116 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEFMEDGA_00814 7.3e-121 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEFMEDGA_00815 1.4e-251 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEFMEDGA_00818 8.6e-242 patB 4.4.1.8 E Aminotransferase, class I II
HEFMEDGA_00819 1.6e-236 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HEFMEDGA_00820 1.1e-167 fmt2 3.2.2.10 S Belongs to the LOG family
HEFMEDGA_00821 4.5e-115 safC S O-methyltransferase
HEFMEDGA_00822 2.7e-182 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
HEFMEDGA_00823 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HEFMEDGA_00824 0.0 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HEFMEDGA_00825 2.2e-290 comM O Magnesium chelatase, subunit ChlI C-terminal
HEFMEDGA_00826 3.7e-75 yraN L Belongs to the UPF0102 family
HEFMEDGA_00827 4.7e-23 L Transposase and inactivated derivatives IS30 family
HEFMEDGA_00828 2.1e-165 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HEFMEDGA_00829 4.5e-252 metY 2.5.1.49 E Aminotransferase class-V
HEFMEDGA_00830 7.8e-166 V ABC transporter, ATP-binding protein
HEFMEDGA_00831 0.0 MV MacB-like periplasmic core domain
HEFMEDGA_00832 3.2e-139 K helix_turn_helix, Lux Regulon
HEFMEDGA_00833 0.0 tcsS2 T Histidine kinase
HEFMEDGA_00834 4.1e-294 pip 3.4.11.5 S alpha/beta hydrolase fold
HEFMEDGA_00835 1.4e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEFMEDGA_00836 9.6e-155 cjaA ET Bacterial periplasmic substrate-binding proteins
HEFMEDGA_00837 5.8e-138 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
HEFMEDGA_00838 1.2e-118 E Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00839 8.1e-109 papP E Binding-protein-dependent transport system inner membrane component
HEFMEDGA_00840 4.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEFMEDGA_00841 7.3e-59 yccF S Inner membrane component domain
HEFMEDGA_00842 2.2e-11
HEFMEDGA_00843 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
HEFMEDGA_00844 1.2e-13 EGP Transmembrane secretion effector
HEFMEDGA_00845 8.4e-285 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEFMEDGA_00846 2.8e-243 nagA 3.5.1.25 G Amidohydrolase family
HEFMEDGA_00847 1.9e-147 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEFMEDGA_00848 4.3e-175 2.7.1.2 GK ROK family
HEFMEDGA_00849 5.4e-220 GK ROK family
HEFMEDGA_00850 4.4e-160 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
HEFMEDGA_00851 7.5e-253 gtr U Sugar (and other) transporter
HEFMEDGA_00852 0.0 P Domain of unknown function (DUF4976)
HEFMEDGA_00853 4e-272 aslB C Iron-sulfur cluster-binding domain
HEFMEDGA_00854 3.2e-107 S Sulfite exporter TauE/SafE
HEFMEDGA_00855 9.2e-22 L Helix-turn-helix domain
HEFMEDGA_00856 1.1e-26 L Helix-turn-helix domain
HEFMEDGA_00857 7.6e-66 S Sulfite exporter TauE/SafE
HEFMEDGA_00858 1.7e-63 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEFMEDGA_00860 1.2e-239 EGP Major facilitator Superfamily
HEFMEDGA_00861 3.9e-107 3.1.3.27 E haloacid dehalogenase-like hydrolase
HEFMEDGA_00862 4.7e-162 3.1.3.73 G Phosphoglycerate mutase family
HEFMEDGA_00863 3.2e-234 rutG F Permease family
HEFMEDGA_00864 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HEFMEDGA_00865 1.1e-258 nplT G Alpha amylase, catalytic domain
HEFMEDGA_00866 9.8e-189 pit P Phosphate transporter family
HEFMEDGA_00867 1.3e-113 MA20_27875 P Protein of unknown function DUF47
HEFMEDGA_00868 4.1e-113 K helix_turn_helix, Lux Regulon
HEFMEDGA_00869 1.6e-241 T Histidine kinase
HEFMEDGA_00870 7.2e-94 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HEFMEDGA_00871 6.5e-187 V ATPases associated with a variety of cellular activities
HEFMEDGA_00872 2.2e-224 V ABC-2 family transporter protein
HEFMEDGA_00873 1.6e-255 V ABC-2 family transporter protein
HEFMEDGA_00874 1.2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HEFMEDGA_00875 1.5e-39 E GDSL-like Lipase/Acylhydrolase family
HEFMEDGA_00876 5.6e-196
HEFMEDGA_00877 9.1e-110 3.4.13.21 E Peptidase family S51
HEFMEDGA_00878 2.4e-110 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
HEFMEDGA_00879 3.8e-160 M pfam nlp p60
HEFMEDGA_00880 2.3e-153 I Serine aminopeptidase, S33
HEFMEDGA_00881 4.1e-30 yozG K Cro/C1-type HTH DNA-binding domain
HEFMEDGA_00882 1.3e-53 S Protein of unknown function (DUF2975)
HEFMEDGA_00883 5.7e-242 pbuX F Permease family
HEFMEDGA_00884 4.8e-105 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEFMEDGA_00885 0.0 pcrA 3.6.4.12 L DNA helicase
HEFMEDGA_00886 3.4e-62 S Domain of unknown function (DUF4418)
HEFMEDGA_00887 1.1e-217 V FtsX-like permease family
HEFMEDGA_00888 3.1e-159 lolD V ABC transporter
HEFMEDGA_00889 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEFMEDGA_00890 1.8e-155 S Peptidase C26
HEFMEDGA_00891 2.5e-91 3.5.4.5 F cytidine deaminase activity
HEFMEDGA_00892 7.6e-45 sdpI S SdpI/YhfL protein family
HEFMEDGA_00893 3e-110 E Transglutaminase-like superfamily
HEFMEDGA_00894 7.1e-67 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HEFMEDGA_00895 1.2e-48 relB L RelB antitoxin
HEFMEDGA_00896 1.9e-129 pgm3 G Phosphoglycerate mutase family
HEFMEDGA_00897 2.3e-55 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HEFMEDGA_00898 1.6e-35
HEFMEDGA_00899 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEFMEDGA_00900 2.7e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEFMEDGA_00901 5.1e-194 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEFMEDGA_00902 3.1e-70 3.4.23.43 S Type IV leader peptidase family
HEFMEDGA_00903 2.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEFMEDGA_00904 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEFMEDGA_00905 1.3e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HEFMEDGA_00906 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEFMEDGA_00907 0.0 S L,D-transpeptidase catalytic domain
HEFMEDGA_00908 4.3e-291 sufB O FeS assembly protein SufB
HEFMEDGA_00909 4.3e-236 sufD O FeS assembly protein SufD
HEFMEDGA_00910 7e-144 sufC O FeS assembly ATPase SufC
HEFMEDGA_00911 1.1e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEFMEDGA_00912 8.1e-102 iscU C SUF system FeS assembly protein, NifU family
HEFMEDGA_00913 3.2e-109 yitW S Iron-sulfur cluster assembly protein
HEFMEDGA_00914 6.2e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HEFMEDGA_00915 3.3e-166 spoU 2.1.1.185 J SpoU rRNA Methylase family
HEFMEDGA_00917 4.6e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEFMEDGA_00918 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HEFMEDGA_00919 2.5e-217 phoH T PhoH-like protein
HEFMEDGA_00920 1.2e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEFMEDGA_00921 9.6e-248 corC S CBS domain
HEFMEDGA_00922 4.3e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEFMEDGA_00923 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HEFMEDGA_00924 4.8e-205 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HEFMEDGA_00925 2.1e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HEFMEDGA_00926 3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HEFMEDGA_00927 3.2e-234 yhjX EGP Major facilitator Superfamily
HEFMEDGA_00928 3.3e-99 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HEFMEDGA_00929 1.6e-226 ilvE 2.6.1.42 E Amino-transferase class IV
HEFMEDGA_00930 1.8e-143 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
HEFMEDGA_00931 7e-136 S UPF0126 domain
HEFMEDGA_00932 5.8e-34 rpsT J Binds directly to 16S ribosomal RNA
HEFMEDGA_00933 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEFMEDGA_00934 3.3e-255 hemN H Involved in the biosynthesis of porphyrin-containing compound
HEFMEDGA_00936 1.2e-191 K helix_turn _helix lactose operon repressor
HEFMEDGA_00937 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HEFMEDGA_00938 1.8e-300 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HEFMEDGA_00939 0.0 E ABC transporter, substrate-binding protein, family 5
HEFMEDGA_00940 0.0 S Glycosyl hydrolases related to GH101 family, GH129
HEFMEDGA_00941 5.9e-82
HEFMEDGA_00942 2.5e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
HEFMEDGA_00943 2.4e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
HEFMEDGA_00944 4.2e-158 S Sucrose-6F-phosphate phosphohydrolase
HEFMEDGA_00946 1e-88 G transmembrane transporter activity
HEFMEDGA_00948 1.1e-204 EGP Major facilitator Superfamily
HEFMEDGA_00949 5.5e-19 S ThiS family
HEFMEDGA_00950 1.2e-86 L Transposase, Mutator family
HEFMEDGA_00951 2.3e-93 bcp 1.11.1.15 O Redoxin
HEFMEDGA_00952 1.8e-142
HEFMEDGA_00956 1.5e-135 yfbU S YfbU domain
HEFMEDGA_00958 8.8e-34 rarD S EamA-like transporter family
HEFMEDGA_00959 9.2e-126 S Plasmid pRiA4b ORF-3-like protein
HEFMEDGA_00960 4.7e-128
HEFMEDGA_00962 1.5e-177 I alpha/beta hydrolase fold
HEFMEDGA_00963 2e-91 S Appr-1'-p processing enzyme
HEFMEDGA_00964 3.6e-145 S phosphoesterase or phosphohydrolase
HEFMEDGA_00965 2.6e-140 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEFMEDGA_00967 1.7e-133 S Phospholipase/Carboxylesterase
HEFMEDGA_00968 4.5e-202 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HEFMEDGA_00969 1.3e-99 sixA 3.6.1.55 T Phosphoglycerate mutase family
HEFMEDGA_00971 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEFMEDGA_00972 5.7e-163 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
HEFMEDGA_00973 4.8e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEFMEDGA_00974 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HEFMEDGA_00975 8.3e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HEFMEDGA_00976 7e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HEFMEDGA_00977 7.4e-291 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEFMEDGA_00978 9.4e-175 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
HEFMEDGA_00979 6.9e-158 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HEFMEDGA_00980 3.1e-181 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEFMEDGA_00981 5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEFMEDGA_00982 3.4e-28
HEFMEDGA_00983 3.6e-218 MA20_36090 S Psort location Cytoplasmic, score 8.87
HEFMEDGA_00984 9.4e-172 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
HEFMEDGA_00985 9.4e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HEFMEDGA_00986 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEFMEDGA_00987 1.1e-300 ybiT S ABC transporter
HEFMEDGA_00988 1.4e-130 S Enoyl-(Acyl carrier protein) reductase
HEFMEDGA_00989 5.2e-56 P ABC transporter
HEFMEDGA_00990 8.3e-59 P ABC transporter
HEFMEDGA_00991 3.6e-50 XK26_04485 P Cobalt transport protein
HEFMEDGA_00992 3.8e-32 XK26_04485 P Cobalt transport protein
HEFMEDGA_00993 5e-234 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HEFMEDGA_00994 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEFMEDGA_00995 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEFMEDGA_00996 2.8e-190 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
HEFMEDGA_00997 1.9e-178 rapZ S Displays ATPase and GTPase activities
HEFMEDGA_00998 3.5e-169 whiA K May be required for sporulation
HEFMEDGA_00999 3.5e-219 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
HEFMEDGA_01000 3.5e-146 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEFMEDGA_01001 2.5e-34 secG U Preprotein translocase SecG subunit
HEFMEDGA_01002 1.1e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HEFMEDGA_01003 6.5e-159 S Sucrose-6F-phosphate phosphohydrolase
HEFMEDGA_01004 1e-300 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HEFMEDGA_01005 1.1e-183
HEFMEDGA_01006 4.5e-239 brnQ U Component of the transport system for branched-chain amino acids
HEFMEDGA_01007 3.6e-202 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEFMEDGA_01008 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
HEFMEDGA_01009 1.1e-190 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEFMEDGA_01010 6.8e-212 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEFMEDGA_01011 1.4e-18
HEFMEDGA_01012 4.1e-85 3.2.1.20, 3.5.1.28 GH31 V N-acetylmuramoyl-L-alanine amidase
HEFMEDGA_01013 2e-59
HEFMEDGA_01014 2.1e-27
HEFMEDGA_01015 3.5e-38 CP_0766 2.7.13.3 D nuclear chromosome segregation
HEFMEDGA_01016 4.2e-135
HEFMEDGA_01017 2.6e-25
HEFMEDGA_01018 1.7e-56
HEFMEDGA_01019 1.6e-192 S Phage-related minor tail protein
HEFMEDGA_01020 3e-34
HEFMEDGA_01021 2.1e-56
HEFMEDGA_01022 7.6e-81
HEFMEDGA_01023 4.6e-41
HEFMEDGA_01024 4.5e-38
HEFMEDGA_01025 1.2e-52
HEFMEDGA_01026 1.2e-60
HEFMEDGA_01027 7.1e-81 S P22 coat protein-protein 5 domain protein
HEFMEDGA_01028 6.3e-23
HEFMEDGA_01029 9.3e-100
HEFMEDGA_01030 1.3e-167 S Phage portal protein, SPP1 Gp6-like
HEFMEDGA_01031 3.8e-98 S Terminase
HEFMEDGA_01032 2.1e-165 S Terminase
HEFMEDGA_01033 1.3e-27
HEFMEDGA_01034 5.8e-41
HEFMEDGA_01037 3.1e-27 K Transcriptional regulator
HEFMEDGA_01038 2.8e-92 J tRNA 5'-leader removal
HEFMEDGA_01044 1.8e-35 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HEFMEDGA_01046 5.4e-63 V HNH endonuclease
HEFMEDGA_01048 1.1e-83 K ParB-like nuclease domain
HEFMEDGA_01050 5.1e-13
HEFMEDGA_01051 1.5e-55 ssb1 L Single-stranded DNA-binding protein
HEFMEDGA_01057 4e-17
HEFMEDGA_01059 7.1e-29 K Cro/C1-type HTH DNA-binding domain
HEFMEDGA_01060 9.9e-12 K Helix-turn-helix XRE-family like proteins
HEFMEDGA_01061 4.5e-119 S Virulence protein RhuM family
HEFMEDGA_01062 7.4e-55
HEFMEDGA_01063 2.8e-63
HEFMEDGA_01064 1.4e-98
HEFMEDGA_01065 2.6e-22
HEFMEDGA_01066 3.5e-115 L Phage integrase family
HEFMEDGA_01067 1.8e-155 G Fructosamine kinase
HEFMEDGA_01068 1.8e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEFMEDGA_01069 1.3e-135 S PAC2 family
HEFMEDGA_01075 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEFMEDGA_01076 2.6e-111 hit 2.7.7.53 FG HIT domain
HEFMEDGA_01077 2e-111 yebC K transcriptional regulatory protein
HEFMEDGA_01078 2.7e-100 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HEFMEDGA_01079 3.2e-107 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEFMEDGA_01080 9.4e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEFMEDGA_01081 1.2e-52 yajC U Preprotein translocase subunit
HEFMEDGA_01082 2.7e-100 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEFMEDGA_01083 3.1e-223 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HEFMEDGA_01084 2.9e-165 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEFMEDGA_01085 6e-236
HEFMEDGA_01086 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HEFMEDGA_01087 4.8e-32
HEFMEDGA_01088 2.9e-120 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HEFMEDGA_01089 1.2e-143 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEFMEDGA_01090 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
HEFMEDGA_01092 2.7e-165 supH S Sucrose-6F-phosphate phosphohydrolase
HEFMEDGA_01093 1.1e-294 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HEFMEDGA_01094 0.0 pafB K WYL domain
HEFMEDGA_01095 6.8e-53
HEFMEDGA_01096 0.0 helY L DEAD DEAH box helicase
HEFMEDGA_01097 5.1e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HEFMEDGA_01098 5.7e-140 pgp 3.1.3.18 S HAD-hyrolase-like
HEFMEDGA_01099 4.7e-37
HEFMEDGA_01100 3.8e-64
HEFMEDGA_01101 2.6e-112 K helix_turn_helix, mercury resistance
HEFMEDGA_01102 6.7e-75 garA T Inner membrane component of T3SS, cytoplasmic domain
HEFMEDGA_01103 8.5e-140 S Bacterial protein of unknown function (DUF881)
HEFMEDGA_01104 3.9e-35 sbp S Protein of unknown function (DUF1290)
HEFMEDGA_01105 4.6e-169 S Bacterial protein of unknown function (DUF881)
HEFMEDGA_01106 1.2e-106 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEFMEDGA_01107 7.9e-157 hisG 2.4.2.17 F ATP phosphoribosyltransferase
HEFMEDGA_01108 9.9e-42 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HEFMEDGA_01109 9.4e-113 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
HEFMEDGA_01110 1.5e-185 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEFMEDGA_01111 3.2e-161 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEFMEDGA_01112 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEFMEDGA_01113 5.1e-127 S SOS response associated peptidase (SRAP)
HEFMEDGA_01114 1.4e-156 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEFMEDGA_01115 1.1e-259 mmuP E amino acid
HEFMEDGA_01116 1.9e-50 EGP Major facilitator Superfamily
HEFMEDGA_01117 5.5e-189 V VanZ like family
HEFMEDGA_01118 1.8e-65 cefD 5.1.1.17 E Aminotransferase, class V
HEFMEDGA_01119 3.6e-99 S Acetyltransferase (GNAT) domain
HEFMEDGA_01120 3.3e-50
HEFMEDGA_01121 5.2e-121
HEFMEDGA_01124 2e-35 2.7.13.3 T Histidine kinase
HEFMEDGA_01125 1.3e-202 2.7.13.3 T Histidine kinase
HEFMEDGA_01126 3.5e-126 K helix_turn_helix, Lux Regulon
HEFMEDGA_01127 3e-95
HEFMEDGA_01128 3.6e-144 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEFMEDGA_01129 1.9e-124 lolD Q ATPases associated with a variety of cellular activities
HEFMEDGA_01130 1.9e-175 V MacB-like periplasmic core domain
HEFMEDGA_01131 9.3e-40 relB L RelB antitoxin
HEFMEDGA_01132 3.2e-49 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HEFMEDGA_01133 3.2e-22 2.7.13.3 T Histidine kinase
HEFMEDGA_01134 8e-94 rpoE4 K Sigma-70 region 2
HEFMEDGA_01135 6.5e-23 S Psort location CytoplasmicMembrane, score
HEFMEDGA_01136 2.1e-106
HEFMEDGA_01137 6.4e-137
HEFMEDGA_01138 7.1e-169 yfiL V ATPases associated with a variety of cellular activities
HEFMEDGA_01139 6.9e-71
HEFMEDGA_01140 1.4e-62
HEFMEDGA_01141 4.5e-147 S EamA-like transporter family
HEFMEDGA_01142 1.4e-102
HEFMEDGA_01143 2.5e-127
HEFMEDGA_01144 2.2e-122 V ATPases associated with a variety of cellular activities
HEFMEDGA_01145 8.8e-16 fic D Fic/DOC family
HEFMEDGA_01146 4.1e-23
HEFMEDGA_01147 3.5e-109
HEFMEDGA_01148 1.3e-45 K sequence-specific DNA binding
HEFMEDGA_01149 8.3e-34 hipA 2.7.11.1 S kinase activity
HEFMEDGA_01150 4.4e-42 2.6.1.76 EGP Major Facilitator Superfamily
HEFMEDGA_01151 6.3e-20 G Major facilitator Superfamily
HEFMEDGA_01152 4.7e-296 mmuP E amino acid
HEFMEDGA_01154 1e-62 yeaO K Protein of unknown function, DUF488
HEFMEDGA_01155 5.3e-77
HEFMEDGA_01156 5e-174 3.6.4.12
HEFMEDGA_01157 4e-65 yijF S Domain of unknown function (DUF1287)
HEFMEDGA_01158 9.9e-299 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEFMEDGA_01159 5.3e-71 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HEFMEDGA_01160 6.1e-140 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEFMEDGA_01161 3.3e-71 3.5.1.124 S DJ-1/PfpI family
HEFMEDGA_01162 2.7e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEFMEDGA_01163 3.7e-174 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
HEFMEDGA_01164 1.5e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEFMEDGA_01165 2.8e-134 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HEFMEDGA_01166 1.4e-145 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEFMEDGA_01167 5.8e-144 rpsB J Belongs to the universal ribosomal protein uS2 family
HEFMEDGA_01168 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEFMEDGA_01169 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
HEFMEDGA_01170 3.3e-91
HEFMEDGA_01171 4e-209 guaB 1.1.1.205 F IMP dehydrogenase family protein
HEFMEDGA_01172 4.6e-243 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HEFMEDGA_01173 2e-257 G ABC transporter substrate-binding protein
HEFMEDGA_01174 2.4e-36 M Peptidase family M23
HEFMEDGA_01175 3e-173 xerH L Phage integrase family
HEFMEDGA_01177 2.8e-134 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HEFMEDGA_01178 6e-87 K Psort location Cytoplasmic, score
HEFMEDGA_01179 2.3e-29 S Fic/DOC family
HEFMEDGA_01182 1.8e-57 ard S Antirestriction protein (ArdA)
HEFMEDGA_01183 2.3e-08
HEFMEDGA_01184 3e-84 M G5 domain protein
HEFMEDGA_01185 7.7e-68
HEFMEDGA_01188 7.7e-241 topB 5.99.1.2 L DNA topoisomerase
HEFMEDGA_01191 2.8e-16 K Bacterial mobilisation protein (MobC)
HEFMEDGA_01192 2.2e-36 S Pfam:CtkA_N
HEFMEDGA_01194 5.6e-62 ecoRIIR 3.1.21.4 L EcoRII C terminal
HEFMEDGA_01195 2.7e-143 S Fic/DOC family
HEFMEDGA_01196 1.5e-138 L PFAM Relaxase mobilization nuclease family protein
HEFMEDGA_01197 1.3e-86 2.7.11.1 S HipA-like C-terminal domain
HEFMEDGA_01199 5.2e-39
HEFMEDGA_01200 2.5e-50 S Domain of unknown function (DUF4913)
HEFMEDGA_01201 1.6e-231 U TraM recognition site of TraD and TraG
HEFMEDGA_01202 2.5e-22
HEFMEDGA_01206 8.9e-202 traD S COG0433 Predicted ATPase
HEFMEDGA_01207 4.9e-186
HEFMEDGA_01208 7.6e-142
HEFMEDGA_01209 1.7e-29
HEFMEDGA_01210 3.4e-32
HEFMEDGA_01211 6.7e-08
HEFMEDGA_01212 8e-21
HEFMEDGA_01213 0.0 XK27_00515 D Cell surface antigen C-terminus
HEFMEDGA_01214 8.8e-38
HEFMEDGA_01216 7.7e-22
HEFMEDGA_01218 3.6e-31 parA D VirC1 protein
HEFMEDGA_01221 1.7e-15 S Transcription factor WhiB
HEFMEDGA_01222 1.7e-15 S Helix-turn-helix domain
HEFMEDGA_01228 1.9e-16
HEFMEDGA_01230 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEFMEDGA_01231 4.2e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
HEFMEDGA_01232 1e-159 yeaZ 2.3.1.234 O Glycoprotease family
HEFMEDGA_01233 1.5e-87 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
HEFMEDGA_01234 2.4e-173 holA 2.7.7.7 L DNA polymerase III delta subunit
HEFMEDGA_01235 9.5e-311 comE S Competence protein
HEFMEDGA_01236 1.6e-44 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
HEFMEDGA_01237 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEFMEDGA_01238 1.1e-158 ET Bacterial periplasmic substrate-binding proteins
HEFMEDGA_01239 5.3e-170 corA P CorA-like Mg2+ transporter protein
HEFMEDGA_01240 5.4e-166 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HEFMEDGA_01241 7.2e-231 L ribosomal rna small subunit methyltransferase
HEFMEDGA_01242 4.1e-71 pdxH S Pfam:Pyridox_oxidase
HEFMEDGA_01243 2.4e-170 EG EamA-like transporter family
HEFMEDGA_01244 2.1e-131 C Putative TM nitroreductase
HEFMEDGA_01245 5e-32
HEFMEDGA_01246 1.3e-254 S Metal-independent alpha-mannosidase (GH125)
HEFMEDGA_01247 5.2e-242 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HEFMEDGA_01248 2.9e-183 K helix_turn _helix lactose operon repressor
HEFMEDGA_01249 0.0 G Glycosyl hydrolase family 85
HEFMEDGA_01250 0.0 bglX-2 3.2.1.21 GH3 G Glycosyl hydrolase family 3 C-terminal domain
HEFMEDGA_01251 8.8e-253 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HEFMEDGA_01252 3e-156 lacG G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01253 1.2e-169 G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01254 7.1e-250 srrA1 G Bacterial extracellular solute-binding protein
HEFMEDGA_01255 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
HEFMEDGA_01256 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
HEFMEDGA_01257 6.1e-16 L Phage integrase family
HEFMEDGA_01258 9.8e-296 L PFAM Integrase catalytic
HEFMEDGA_01259 3.6e-148 L IstB-like ATP binding protein
HEFMEDGA_01260 6.8e-19
HEFMEDGA_01261 1.9e-170 S Fic/DOC family
HEFMEDGA_01262 2.1e-249 S HipA-like C-terminal domain
HEFMEDGA_01264 2.3e-74
HEFMEDGA_01265 6e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEFMEDGA_01266 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEFMEDGA_01267 1.7e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HEFMEDGA_01268 1.4e-47 S Domain of unknown function (DUF4193)
HEFMEDGA_01269 3.2e-147 S Protein of unknown function (DUF3071)
HEFMEDGA_01270 1.5e-233 S Type I phosphodiesterase / nucleotide pyrophosphatase
HEFMEDGA_01271 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HEFMEDGA_01272 3.2e-09 E GDSL-like Lipase/Acylhydrolase
HEFMEDGA_01273 1.3e-110 G Bacterial extracellular solute-binding protein
HEFMEDGA_01274 3.5e-43 K AraC-like ligand binding domain
HEFMEDGA_01275 5.2e-43 K Psort location Cytoplasmic, score
HEFMEDGA_01276 1.2e-48 K Psort location Cytoplasmic, score
HEFMEDGA_01277 0.0 lhr L DEAD DEAH box helicase
HEFMEDGA_01278 3.1e-173 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEFMEDGA_01279 4.5e-222 G Major Facilitator Superfamily
HEFMEDGA_01280 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HEFMEDGA_01281 8.2e-191 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEFMEDGA_01282 9.6e-115
HEFMEDGA_01283 3.2e-195 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
HEFMEDGA_01284 0.0 pknL 2.7.11.1 KLT PASTA
HEFMEDGA_01285 6.2e-131 plsC2 2.3.1.51 I Phosphate acyltransferases
HEFMEDGA_01286 3.2e-116
HEFMEDGA_01287 1.7e-193 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEFMEDGA_01288 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEFMEDGA_01289 2.4e-113 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEFMEDGA_01290 3.5e-103 recX S Modulates RecA activity
HEFMEDGA_01291 8.3e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEFMEDGA_01292 1.2e-31 S Protein of unknown function (DUF3046)
HEFMEDGA_01293 1.1e-76 K Helix-turn-helix XRE-family like proteins
HEFMEDGA_01294 6e-97 cinA 3.5.1.42 S Belongs to the CinA family
HEFMEDGA_01295 2.7e-117 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEFMEDGA_01296 0.0 ftsK D FtsK SpoIIIE family protein
HEFMEDGA_01297 4.6e-150 fic D Fic/DOC family
HEFMEDGA_01298 9.1e-181 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEFMEDGA_01299 1.3e-276 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEFMEDGA_01300 5.2e-150 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HEFMEDGA_01301 3.6e-166 ydeD EG EamA-like transporter family
HEFMEDGA_01302 2.8e-135 ybhL S Belongs to the BI1 family
HEFMEDGA_01303 6.4e-82 K helix_turn_helix, Lux Regulon
HEFMEDGA_01304 6.8e-121 E Psort location Cytoplasmic, score 8.87
HEFMEDGA_01305 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEFMEDGA_01306 0.0 ctpE P E1-E2 ATPase
HEFMEDGA_01307 2e-98
HEFMEDGA_01308 3.2e-239 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEFMEDGA_01309 3.8e-134 S Protein of unknown function (DUF3159)
HEFMEDGA_01310 7.3e-155 S Protein of unknown function (DUF3710)
HEFMEDGA_01311 3.3e-171 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HEFMEDGA_01312 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
HEFMEDGA_01313 1.1e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
HEFMEDGA_01314 8.9e-154 dppB EP Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01315 0.0 E ABC transporter, substrate-binding protein, family 5
HEFMEDGA_01316 3.6e-188 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HEFMEDGA_01317 6.4e-148 V ABC transporter, ATP-binding protein
HEFMEDGA_01318 0.0 MV MacB-like periplasmic core domain
HEFMEDGA_01319 2.9e-41
HEFMEDGA_01320 6.5e-190 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HEFMEDGA_01321 2e-188 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HEFMEDGA_01322 1.1e-78
HEFMEDGA_01323 0.0 typA T Elongation factor G C-terminus
HEFMEDGA_01324 7e-107 K Virulence activator alpha C-term
HEFMEDGA_01325 4.8e-137 V ATPases associated with a variety of cellular activities
HEFMEDGA_01326 0.0 V FtsX-like permease family
HEFMEDGA_01327 1.3e-18 naiP U Sugar (and other) transporter
HEFMEDGA_01328 1.3e-238 iscS1 2.8.1.7 E Aminotransferase class-V
HEFMEDGA_01329 1.9e-161 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
HEFMEDGA_01330 1.7e-298 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HEFMEDGA_01331 5.4e-250 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HEFMEDGA_01332 7.5e-160 nrtR 3.6.1.55 F NUDIX hydrolase
HEFMEDGA_01333 1.6e-115 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEFMEDGA_01334 8.5e-151 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEFMEDGA_01335 3.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HEFMEDGA_01336 8.3e-160 xerD D recombinase XerD
HEFMEDGA_01337 6.6e-215 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HEFMEDGA_01338 1.3e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEFMEDGA_01339 6.2e-25 rpmI J Ribosomal protein L35
HEFMEDGA_01340 1.7e-113 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEFMEDGA_01341 2.1e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HEFMEDGA_01342 3.7e-196 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEFMEDGA_01343 1.2e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEFMEDGA_01344 3.7e-182 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEFMEDGA_01345 4.2e-191 galM 5.1.3.3 G Aldose 1-epimerase
HEFMEDGA_01346 7.3e-188 galM 5.1.3.3 G Aldose 1-epimerase
HEFMEDGA_01347 3.3e-52
HEFMEDGA_01348 1.5e-135 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HEFMEDGA_01349 3e-276 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEFMEDGA_01350 6.9e-192 V Acetyltransferase (GNAT) domain
HEFMEDGA_01351 6.6e-69 V Acetyltransferase (GNAT) domain
HEFMEDGA_01352 0.0 smc D Required for chromosome condensation and partitioning
HEFMEDGA_01353 4.9e-301 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
HEFMEDGA_01354 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HEFMEDGA_01355 6.6e-98 3.6.1.55 F NUDIX domain
HEFMEDGA_01356 3.8e-248 nagA 3.5.1.25 G Amidohydrolase family
HEFMEDGA_01357 2.1e-151 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEFMEDGA_01358 2.4e-209 GK ROK family
HEFMEDGA_01359 2.2e-165 2.7.1.2 GK ROK family
HEFMEDGA_01360 3e-226 GK ROK family
HEFMEDGA_01361 1.2e-168 2.7.1.4 G pfkB family carbohydrate kinase
HEFMEDGA_01362 6.5e-97 G Major Facilitator Superfamily
HEFMEDGA_01363 2.2e-87 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEFMEDGA_01364 7.7e-14
HEFMEDGA_01365 7.3e-173 ftsQ 6.3.2.4 D Cell division protein FtsQ
HEFMEDGA_01366 1.8e-284 murC 6.3.2.8 M Belongs to the MurCDEF family
HEFMEDGA_01367 2.3e-215 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEFMEDGA_01368 2.5e-225 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HEFMEDGA_01369 3.3e-272 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEFMEDGA_01370 1.2e-205 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEFMEDGA_01371 3e-241 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEFMEDGA_01372 2e-155 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEFMEDGA_01373 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HEFMEDGA_01374 4e-67 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HEFMEDGA_01375 5.7e-189 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEFMEDGA_01376 1.3e-93 mraZ K Belongs to the MraZ family
HEFMEDGA_01377 0.0 L DNA helicase
HEFMEDGA_01378 7.5e-230 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HEFMEDGA_01379 8.4e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEFMEDGA_01380 3e-47 M Lysin motif
HEFMEDGA_01381 6.9e-130 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEFMEDGA_01382 7.7e-161 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEFMEDGA_01383 1.7e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HEFMEDGA_01384 2e-272 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEFMEDGA_01385 7.5e-123 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HEFMEDGA_01386 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HEFMEDGA_01387 1.1e-217 EGP Major facilitator Superfamily
HEFMEDGA_01388 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
HEFMEDGA_01389 1.3e-276 S Uncharacterized protein conserved in bacteria (DUF2252)
HEFMEDGA_01390 1.3e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HEFMEDGA_01391 1.4e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEFMEDGA_01392 3.6e-97
HEFMEDGA_01393 2.7e-111 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HEFMEDGA_01394 2.8e-221 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEFMEDGA_01395 1.5e-253 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEFMEDGA_01396 3.1e-53 acyP 3.6.1.7 C Acylphosphatase
HEFMEDGA_01397 7.7e-157 yvgN 1.1.1.346 S Aldo/keto reductase family
HEFMEDGA_01398 0.0 2.4.1.230, 3.2.1.51 GH65,GH95 G Glycosyl hydrolase family 65, N-terminal domain
HEFMEDGA_01399 2.2e-165 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
HEFMEDGA_01400 9.6e-141 IQ KR domain
HEFMEDGA_01401 8.6e-98 4.2.1.68 M Enolase C-terminal domain-like
HEFMEDGA_01402 1.2e-37 4.2.1.68 M Enolase C-terminal domain-like
HEFMEDGA_01403 9.2e-10
HEFMEDGA_01404 0.0 4.2.1.53 S MCRA family
HEFMEDGA_01405 1.9e-166 dkgA 1.1.1.346 C Aldo/keto reductase family
HEFMEDGA_01406 2.8e-38 yneG S Domain of unknown function (DUF4186)
HEFMEDGA_01407 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HEFMEDGA_01408 7.1e-200 K WYL domain
HEFMEDGA_01409 5.8e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HEFMEDGA_01410 5.4e-90 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEFMEDGA_01411 5.3e-22 tccB2 V DivIVA protein
HEFMEDGA_01412 4.9e-45 yggT S YGGT family
HEFMEDGA_01413 5.9e-69 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEFMEDGA_01414 1.2e-211 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEFMEDGA_01415 5.7e-249 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEFMEDGA_01416 6.7e-297 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HEFMEDGA_01417 2.4e-154 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEFMEDGA_01418 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEFMEDGA_01419 1.6e-227 O AAA domain (Cdc48 subfamily)
HEFMEDGA_01420 8.2e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HEFMEDGA_01421 5.6e-62 S Thiamine-binding protein
HEFMEDGA_01422 7.1e-248 ydjK G Sugar (and other) transporter
HEFMEDGA_01423 3.9e-217 2.7.13.3 T Histidine kinase
HEFMEDGA_01424 6.1e-123 K helix_turn_helix, Lux Regulon
HEFMEDGA_01425 4.5e-191
HEFMEDGA_01426 5.4e-259 O SERine Proteinase INhibitors
HEFMEDGA_01427 1.8e-195 K helix_turn _helix lactose operon repressor
HEFMEDGA_01428 6.2e-241 lacY P LacY proton/sugar symporter
HEFMEDGA_01429 2.3e-303 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HEFMEDGA_01430 3.2e-141 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
HEFMEDGA_01431 2.5e-149 C Putative TM nitroreductase
HEFMEDGA_01432 6.4e-198 S Glycosyltransferase, group 2 family protein
HEFMEDGA_01433 1.3e-93 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEFMEDGA_01434 0.0 ecfA GP ABC transporter, ATP-binding protein
HEFMEDGA_01435 3.1e-47 yhbY J CRS1_YhbY
HEFMEDGA_01436 1.6e-53 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HEFMEDGA_01437 2.6e-51
HEFMEDGA_01438 3.8e-187 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HEFMEDGA_01439 4.2e-251 EGP Major facilitator Superfamily
HEFMEDGA_01440 2.3e-33 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HEFMEDGA_01441 6.9e-11 KT Transcriptional regulatory protein, C terminal
HEFMEDGA_01442 1.8e-251 rarA L Recombination factor protein RarA
HEFMEDGA_01443 0.0 helY L DEAD DEAH box helicase
HEFMEDGA_01444 2.8e-199 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
HEFMEDGA_01446 2.9e-287 ydfD EK Alanine-glyoxylate amino-transferase
HEFMEDGA_01447 1.3e-111 argO S LysE type translocator
HEFMEDGA_01448 1.3e-290 phoN I PAP2 superfamily
HEFMEDGA_01449 1e-193 gluD E Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01450 2e-110 gluC E Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01451 5.3e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
HEFMEDGA_01452 3.1e-153 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
HEFMEDGA_01453 6.1e-102 S Aminoacyl-tRNA editing domain
HEFMEDGA_01454 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HEFMEDGA_01455 5.9e-261 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HEFMEDGA_01456 4.4e-224 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HEFMEDGA_01457 0.0 3.1.3.5 F 5'-nucleotidase, C-terminal domain
HEFMEDGA_01458 9.6e-59 lipA I Hydrolase, alpha beta domain protein
HEFMEDGA_01459 3.9e-132 xylE U Sugar (and other) transporter
HEFMEDGA_01460 3.9e-26 K helix_turn_helix, arabinose operon control protein
HEFMEDGA_01461 0.0 clpC O ATPase family associated with various cellular activities (AAA)
HEFMEDGA_01462 1.4e-178 uspA T Belongs to the universal stress protein A family
HEFMEDGA_01463 3.7e-180 S Protein of unknown function (DUF3027)
HEFMEDGA_01464 2.9e-66 cspB K 'Cold-shock' DNA-binding domain
HEFMEDGA_01465 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HEFMEDGA_01466 3.4e-132 KT Response regulator receiver domain protein
HEFMEDGA_01467 4.3e-99
HEFMEDGA_01468 4.2e-33 S Proteins of 100 residues with WXG
HEFMEDGA_01469 1.8e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEFMEDGA_01470 3.9e-37 K 'Cold-shock' DNA-binding domain
HEFMEDGA_01471 6.9e-84 S LytR cell envelope-related transcriptional attenuator
HEFMEDGA_01472 3.8e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEFMEDGA_01473 4.9e-188 moxR S ATPase family associated with various cellular activities (AAA)
HEFMEDGA_01474 1.3e-163 S Protein of unknown function DUF58
HEFMEDGA_01475 3.9e-85
HEFMEDGA_01476 3.3e-189 S von Willebrand factor (vWF) type A domain
HEFMEDGA_01477 1.1e-152 S von Willebrand factor (vWF) type A domain
HEFMEDGA_01478 3.1e-56
HEFMEDGA_01479 5.2e-255 S PGAP1-like protein
HEFMEDGA_01480 2.5e-110 ykoE S ABC-type cobalt transport system, permease component
HEFMEDGA_01481 8.6e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HEFMEDGA_01482 0.0 S Lysylphosphatidylglycerol synthase TM region
HEFMEDGA_01483 8.1e-42 hup L Belongs to the bacterial histone-like protein family
HEFMEDGA_01484 5.4e-286 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HEFMEDGA_01486 8.9e-175 hisN 3.1.3.25 G Inositol monophosphatase family
HEFMEDGA_01487 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HEFMEDGA_01488 8.4e-136 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
HEFMEDGA_01489 1.7e-162 G Phosphotransferase System
HEFMEDGA_01490 2.1e-46 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HEFMEDGA_01491 1.8e-78 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEFMEDGA_01492 8.8e-72 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEFMEDGA_01493 3.8e-279 manR K PRD domain
HEFMEDGA_01494 1.4e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HEFMEDGA_01495 2.2e-285 arc O AAA ATPase forming ring-shaped complexes
HEFMEDGA_01496 2.2e-117 apl 3.1.3.1 S SNARE associated Golgi protein
HEFMEDGA_01497 2.1e-118 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HEFMEDGA_01498 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEFMEDGA_01499 3.6e-131 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HEFMEDGA_01500 1.8e-184 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEFMEDGA_01501 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HEFMEDGA_01502 4.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEFMEDGA_01503 1.1e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEFMEDGA_01504 2.3e-149 G Fic/DOC family
HEFMEDGA_01505 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HEFMEDGA_01506 5.3e-268 K Putative DNA-binding domain
HEFMEDGA_01507 6.2e-83 3.1.21.3 V Type I restriction modification DNA specificity domain
HEFMEDGA_01508 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
HEFMEDGA_01509 3.2e-158 2.7.7.7 L Domain of unknown function (DUF4357)
HEFMEDGA_01510 2.9e-176 L Phage integrase family
HEFMEDGA_01511 6.5e-93 3.1.21.3 V type I restriction modification DNA specificity domain
HEFMEDGA_01512 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEFMEDGA_01513 9.3e-154 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEFMEDGA_01514 4.7e-162 dcuD C C4-dicarboxylate anaerobic carrier
HEFMEDGA_01515 2.6e-105 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HEFMEDGA_01516 2.4e-43 K acetyltransferase
HEFMEDGA_01517 7.9e-127 rbsR K helix_turn _helix lactose operon repressor
HEFMEDGA_01518 0.0 V ABC transporter transmembrane region
HEFMEDGA_01519 0.0 V ABC transporter, ATP-binding protein
HEFMEDGA_01520 5.2e-90 K MarR family
HEFMEDGA_01521 6.7e-178 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HEFMEDGA_01522 3.6e-240 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HEFMEDGA_01523 2.2e-69 S Nucleotidyltransferase substrate binding protein like
HEFMEDGA_01524 1.6e-45 S Nucleotidyltransferase domain
HEFMEDGA_01526 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
HEFMEDGA_01527 9.6e-129 K Bacterial regulatory proteins, tetR family
HEFMEDGA_01528 2.5e-255 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
HEFMEDGA_01529 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HEFMEDGA_01530 3.8e-144 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEFMEDGA_01531 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HEFMEDGA_01532 3.1e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEFMEDGA_01533 2.4e-41 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEFMEDGA_01534 5.1e-91 ywrO 1.6.5.2 S Flavodoxin-like fold
HEFMEDGA_01535 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HEFMEDGA_01536 3.2e-65 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEFMEDGA_01537 3.7e-78 F Nucleoside 2-deoxyribosyltransferase
HEFMEDGA_01539 4.5e-192 S Endonuclease/Exonuclease/phosphatase family
HEFMEDGA_01540 3.2e-178 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HEFMEDGA_01541 3.9e-234 aspB E Aminotransferase class-V
HEFMEDGA_01542 3.2e-200 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
HEFMEDGA_01543 1.1e-85 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HEFMEDGA_01544 4.1e-101 XK27_03610 K Acetyltransferase (GNAT) domain
HEFMEDGA_01545 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
HEFMEDGA_01546 4e-147 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HEFMEDGA_01547 2.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HEFMEDGA_01548 6e-151 map 3.4.11.18 E Methionine aminopeptidase
HEFMEDGA_01549 1.5e-142 S Short repeat of unknown function (DUF308)
HEFMEDGA_01550 0.0 pepO 3.4.24.71 O Peptidase family M13
HEFMEDGA_01551 1.4e-116 L Single-strand binding protein family
HEFMEDGA_01552 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEFMEDGA_01553 2.9e-102 pflA 1.97.1.4 O Radical SAM superfamily
HEFMEDGA_01554 1.2e-35 pflA 1.97.1.4 O Radical SAM superfamily
HEFMEDGA_01555 1.3e-268 recD2 3.6.4.12 L PIF1-like helicase
HEFMEDGA_01556 4.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HEFMEDGA_01557 4.8e-293 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEFMEDGA_01558 3e-213 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HEFMEDGA_01559 1.5e-118 ywlC 2.7.7.87 J Belongs to the SUA5 family
HEFMEDGA_01560 3.6e-123 livF E ATPases associated with a variety of cellular activities
HEFMEDGA_01561 9.5e-150 E Branched-chain amino acid ATP-binding cassette transporter
HEFMEDGA_01562 1e-188 livM U Belongs to the binding-protein-dependent transport system permease family
HEFMEDGA_01563 5.4e-111 U Belongs to the binding-protein-dependent transport system permease family
HEFMEDGA_01564 1.8e-207 livK E Receptor family ligand binding region
HEFMEDGA_01565 3.4e-163 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEFMEDGA_01566 3.7e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEFMEDGA_01567 1.3e-36 rpmE J Binds the 23S rRNA
HEFMEDGA_01569 1.1e-99 yebQ EGP Major facilitator Superfamily
HEFMEDGA_01570 4.8e-148
HEFMEDGA_01571 1.3e-72 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HEFMEDGA_01572 3.5e-165 dkgB S Oxidoreductase, aldo keto reductase family protein
HEFMEDGA_01573 1.9e-18 lmrB U Major Facilitator Superfamily
HEFMEDGA_01574 9.7e-81 K Winged helix DNA-binding domain
HEFMEDGA_01575 7.2e-175 glkA 2.7.1.2 G ROK family
HEFMEDGA_01577 2e-308 EGP Major Facilitator Superfamily
HEFMEDGA_01578 0.0 yjjK S ATP-binding cassette protein, ChvD family
HEFMEDGA_01579 2.5e-169 tesB I Thioesterase-like superfamily
HEFMEDGA_01580 3.5e-86 S Protein of unknown function (DUF3180)
HEFMEDGA_01581 9.4e-225 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEFMEDGA_01582 2.4e-161 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEFMEDGA_01583 2.8e-117 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HEFMEDGA_01584 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEFMEDGA_01585 2.7e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HEFMEDGA_01586 2.2e-210 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEFMEDGA_01587 1.9e-251 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
HEFMEDGA_01588 6.9e-298
HEFMEDGA_01589 1.5e-189 natA V ATPases associated with a variety of cellular activities
HEFMEDGA_01590 4.7e-235 epsG M Glycosyl transferase family 21
HEFMEDGA_01591 1.9e-281 S AI-2E family transporter
HEFMEDGA_01592 2.3e-178 3.4.14.13 M Glycosyltransferase like family 2
HEFMEDGA_01593 5.2e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
HEFMEDGA_01594 1.6e-262 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
HEFMEDGA_01597 9e-162 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEFMEDGA_01599 1.2e-15 L Phage integrase family
HEFMEDGA_01600 1.5e-12 sprF 4.6.1.1 M Cell surface antigen C-terminus
HEFMEDGA_01601 1.3e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
HEFMEDGA_01602 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HEFMEDGA_01603 5.3e-184 lacR K Transcriptional regulator, LacI family
HEFMEDGA_01604 1.4e-21 L Helix-turn-helix domain
HEFMEDGA_01605 3.2e-258 G Bacterial extracellular solute-binding protein
HEFMEDGA_01606 1.3e-221 GK ROK family
HEFMEDGA_01608 0.0 G Glycosyl hydrolase family 20, domain 2
HEFMEDGA_01609 8.9e-219 vex3 V ABC transporter permease
HEFMEDGA_01610 2e-209 vex1 V Efflux ABC transporter, permease protein
HEFMEDGA_01611 4.1e-110 vex2 V ABC transporter, ATP-binding protein
HEFMEDGA_01612 1.4e-11 azlC E AzlC protein
HEFMEDGA_01613 5.9e-97 ptpA 3.1.3.48 T low molecular weight
HEFMEDGA_01614 2.3e-127 folA 1.5.1.3 H dihydrofolate reductase
HEFMEDGA_01615 1e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEFMEDGA_01616 3.4e-73 attW O OsmC-like protein
HEFMEDGA_01617 1.5e-189 T Universal stress protein family
HEFMEDGA_01618 3e-104 M NlpC/P60 family
HEFMEDGA_01619 2.9e-99 M NlpC/P60 family
HEFMEDGA_01620 1.7e-168 usp 3.5.1.28 CBM50 S CHAP domain
HEFMEDGA_01621 1.2e-213 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEFMEDGA_01622 1.8e-32
HEFMEDGA_01623 6e-174 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HEFMEDGA_01624 5.4e-116 phoU P Plays a role in the regulation of phosphate uptake
HEFMEDGA_01625 3.3e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEFMEDGA_01626 4.7e-174 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HEFMEDGA_01627 2.3e-311 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HEFMEDGA_01629 1.3e-218 araJ EGP Major facilitator Superfamily
HEFMEDGA_01630 0.0 S Domain of unknown function (DUF4037)
HEFMEDGA_01631 1.6e-117 S Protein of unknown function (DUF4125)
HEFMEDGA_01632 0.0 S alpha beta
HEFMEDGA_01633 4.4e-68
HEFMEDGA_01634 1.1e-290 pspC KT PspC domain
HEFMEDGA_01635 4.4e-236 tcsS3 KT PspC domain
HEFMEDGA_01636 7.6e-118 degU K helix_turn_helix, Lux Regulon
HEFMEDGA_01637 4.1e-168 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEFMEDGA_01638 8.9e-206 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
HEFMEDGA_01639 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
HEFMEDGA_01640 2.5e-167 G ABC transporter permease
HEFMEDGA_01641 9e-173 malC G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01642 5.5e-250 G Bacterial extracellular solute-binding protein
HEFMEDGA_01644 3.3e-242 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEFMEDGA_01645 4.4e-182 I Diacylglycerol kinase catalytic domain
HEFMEDGA_01646 6.6e-162 arbG K CAT RNA binding domain
HEFMEDGA_01647 0.0 crr 2.7.1.193 G pts system, glucose-specific IIABC component
HEFMEDGA_01648 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HEFMEDGA_01649 3.7e-196 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HEFMEDGA_01650 3.6e-73 K Transcriptional regulator
HEFMEDGA_01651 2.7e-277 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEFMEDGA_01652 1e-172 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEFMEDGA_01653 9.1e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HEFMEDGA_01655 1.6e-98
HEFMEDGA_01656 1.3e-260 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEFMEDGA_01657 1.3e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HEFMEDGA_01658 1.4e-220 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEFMEDGA_01659 4.8e-82 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEFMEDGA_01660 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEFMEDGA_01661 3.4e-186 nusA K Participates in both transcription termination and antitermination
HEFMEDGA_01662 2.1e-126
HEFMEDGA_01663 1.5e-101 K helix_turn _helix lactose operon repressor
HEFMEDGA_01665 1.1e-149 E Transglutaminase/protease-like homologues
HEFMEDGA_01666 0.0 gcs2 S A circularly permuted ATPgrasp
HEFMEDGA_01667 8.7e-170 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEFMEDGA_01668 7.4e-60 rplQ J Ribosomal protein L17
HEFMEDGA_01669 3.4e-183 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEFMEDGA_01670 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEFMEDGA_01671 9.5e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEFMEDGA_01672 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HEFMEDGA_01673 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEFMEDGA_01674 2.2e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEFMEDGA_01675 1.7e-246 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEFMEDGA_01676 8.1e-76 rplO J binds to the 23S rRNA
HEFMEDGA_01677 7e-26 rpmD J Ribosomal protein L30p/L7e
HEFMEDGA_01678 6.7e-96 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEFMEDGA_01679 2.4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEFMEDGA_01680 5.4e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEFMEDGA_01681 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEFMEDGA_01682 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEFMEDGA_01683 4.4e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEFMEDGA_01684 1.3e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEFMEDGA_01685 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEFMEDGA_01686 6.4e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEFMEDGA_01687 4.1e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
HEFMEDGA_01688 2.2e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEFMEDGA_01689 1.7e-100 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEFMEDGA_01690 9.7e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEFMEDGA_01691 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEFMEDGA_01692 1.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEFMEDGA_01693 7.5e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEFMEDGA_01694 3.1e-116 rplD J Forms part of the polypeptide exit tunnel
HEFMEDGA_01695 8.7e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEFMEDGA_01696 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
HEFMEDGA_01697 1.2e-134 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HEFMEDGA_01698 9.5e-145 ywiC S YwiC-like protein
HEFMEDGA_01699 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HEFMEDGA_01700 3.1e-170 rhaR_1 K helix_turn_helix, arabinose operon control protein
HEFMEDGA_01701 1.5e-194 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
HEFMEDGA_01702 2.7e-196 EGP Major facilitator Superfamily
HEFMEDGA_01703 1.1e-214 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HEFMEDGA_01704 6e-75 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEFMEDGA_01705 2.2e-233 EGP Major facilitator Superfamily
HEFMEDGA_01706 5.1e-179 tdh 1.1.1.14 C Zinc-binding dehydrogenase
HEFMEDGA_01707 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HEFMEDGA_01708 3.7e-82 rpsI J Belongs to the universal ribosomal protein uS9 family
HEFMEDGA_01709 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEFMEDGA_01710 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HEFMEDGA_01711 8.4e-117
HEFMEDGA_01712 3.4e-112 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HEFMEDGA_01713 3.1e-184 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFMEDGA_01714 1.8e-117 M Bacterial capsule synthesis protein PGA_cap
HEFMEDGA_01715 6.3e-245 bglA 3.2.1.21 G Glycosyl hydrolase family 1
HEFMEDGA_01716 8e-160 U Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01717 5.5e-164 malC U Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01718 1.7e-243 malE G Bacterial extracellular solute-binding protein
HEFMEDGA_01719 1.4e-217 rbsR K helix_turn _helix lactose operon repressor
HEFMEDGA_01720 5.2e-22
HEFMEDGA_01722 2.7e-75 S EamA-like transporter family
HEFMEDGA_01723 1.5e-17 S EamA-like transporter family
HEFMEDGA_01724 1.4e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEFMEDGA_01725 6.1e-224 dapC E Aminotransferase class I and II
HEFMEDGA_01726 2.9e-59 fdxA C 4Fe-4S binding domain
HEFMEDGA_01727 1.2e-269 E aromatic amino acid transport protein AroP K03293
HEFMEDGA_01728 9.1e-215 murB 1.3.1.98 M Cell wall formation
HEFMEDGA_01729 4.1e-25 rpmG J Ribosomal protein L33
HEFMEDGA_01733 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEFMEDGA_01734 2.4e-135
HEFMEDGA_01735 2.6e-85 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
HEFMEDGA_01736 7.1e-55 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HEFMEDGA_01737 4.3e-31 fmdB S Putative regulatory protein
HEFMEDGA_01738 3.6e-106 flgA NO SAF
HEFMEDGA_01739 6.6e-19 L Superfamily I DNA and RNA helicases and helicase subunits
HEFMEDGA_01740 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HEFMEDGA_01741 5.4e-181 T Forkhead associated domain
HEFMEDGA_01742 9.3e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEFMEDGA_01743 2.4e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEFMEDGA_01744 4e-147 3.2.1.8 S alpha beta
HEFMEDGA_01745 1.1e-251 pbuO S Permease family
HEFMEDGA_01746 1.2e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEFMEDGA_01747 1.3e-171 pstA P Phosphate transport system permease
HEFMEDGA_01748 1.2e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HEFMEDGA_01749 2.8e-202 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HEFMEDGA_01750 1.1e-141 KT Transcriptional regulatory protein, C terminal
HEFMEDGA_01751 2.6e-207 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HEFMEDGA_01752 1e-240 EGP Sugar (and other) transporter
HEFMEDGA_01753 5.7e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEFMEDGA_01754 1.9e-236 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HEFMEDGA_01755 3.4e-216 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HEFMEDGA_01756 8.7e-267 pepC 3.4.22.40 E Peptidase C1-like family
HEFMEDGA_01757 2.4e-44 D nuclear chromosome segregation
HEFMEDGA_01758 3.7e-125 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEFMEDGA_01759 8.4e-151 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HEFMEDGA_01760 2.3e-198 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HEFMEDGA_01761 2.1e-301 yegQ O Peptidase family U32 C-terminal domain
HEFMEDGA_01762 2e-177 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HEFMEDGA_01763 7.7e-103 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HEFMEDGA_01764 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
HEFMEDGA_01765 2.5e-29 rpmB J Ribosomal L28 family
HEFMEDGA_01766 7.1e-197 yegV G pfkB family carbohydrate kinase
HEFMEDGA_01767 1.1e-239 yxiO S Vacuole effluxer Atg22 like
HEFMEDGA_01768 3.7e-82 soxR K helix_turn_helix, mercury resistance
HEFMEDGA_01769 6.9e-62 T Toxic component of a toxin-antitoxin (TA) module
HEFMEDGA_01770 8.1e-54 relB L RelB antitoxin
HEFMEDGA_01771 2.3e-24 yxiO G Major facilitator Superfamily
HEFMEDGA_01772 3.6e-191 K Helix-turn-helix XRE-family like proteins
HEFMEDGA_01774 5.7e-63 S Alpha/beta hydrolase family
HEFMEDGA_01778 7.2e-17 EGP Major facilitator Superfamily
HEFMEDGA_01779 2.3e-56 XK27_04590 S NADPH-dependent FMN reductase
HEFMEDGA_01781 3.8e-293 pccB I Carboxyl transferase domain
HEFMEDGA_01782 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HEFMEDGA_01783 2.6e-90 bioY S BioY family
HEFMEDGA_01784 4.7e-151 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HEFMEDGA_01785 0.0
HEFMEDGA_01786 1.4e-164 QT PucR C-terminal helix-turn-helix domain
HEFMEDGA_01787 2.7e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEFMEDGA_01788 1e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEFMEDGA_01789 1.4e-110 nusG K Participates in transcription elongation, termination and antitermination
HEFMEDGA_01790 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEFMEDGA_01792 5.8e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HEFMEDGA_01793 8e-222 G polysaccharide deacetylase
HEFMEDGA_01794 8.3e-199 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEFMEDGA_01795 9.4e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEFMEDGA_01796 5.8e-39 rpmA J Ribosomal L27 protein
HEFMEDGA_01797 1.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HEFMEDGA_01798 0.0 rne 3.1.26.12 J Ribonuclease E/G family
HEFMEDGA_01799 6.2e-232 dapE 3.5.1.18 E Peptidase dimerisation domain
HEFMEDGA_01800 1.9e-167 mdcF S Transporter, auxin efflux carrier (AEC) family protein
HEFMEDGA_01801 5.7e-166 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
HEFMEDGA_01802 7.1e-149 S Amidohydrolase
HEFMEDGA_01803 3.8e-200 fucP G Major Facilitator Superfamily
HEFMEDGA_01804 3.7e-148 IQ KR domain
HEFMEDGA_01805 1.1e-250 4.2.1.68 M Enolase C-terminal domain-like
HEFMEDGA_01806 1.2e-191 K Bacterial regulatory proteins, lacI family
HEFMEDGA_01807 3.1e-254 V Efflux ABC transporter, permease protein
HEFMEDGA_01808 2e-138 V ATPases associated with a variety of cellular activities
HEFMEDGA_01809 1.6e-28 S Protein of unknown function (DUF1778)
HEFMEDGA_01810 2e-91 K Acetyltransferase (GNAT) family
HEFMEDGA_01811 9.3e-283 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HEFMEDGA_01812 3.2e-185 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEFMEDGA_01813 1.8e-237 hom 1.1.1.3 E Homoserine dehydrogenase
HEFMEDGA_01814 4.3e-54 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
HEFMEDGA_01815 5.1e-55 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEFMEDGA_01816 1.7e-282 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEFMEDGA_01817 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HEFMEDGA_01818 8.1e-131 K Bacterial regulatory proteins, tetR family
HEFMEDGA_01819 2.7e-222 G Transmembrane secretion effector
HEFMEDGA_01820 6.8e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEFMEDGA_01821 5.3e-256 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
HEFMEDGA_01822 7.9e-157 ET Bacterial periplasmic substrate-binding proteins
HEFMEDGA_01823 3.7e-120 ytmL P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01824 1.5e-138 P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01825 1.3e-104 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
HEFMEDGA_01826 3.5e-132 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
HEFMEDGA_01827 1.8e-220 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
HEFMEDGA_01828 1.4e-20 2.7.13.3 T Histidine kinase
HEFMEDGA_01829 8.4e-20 S Bacterial PH domain
HEFMEDGA_01830 3.2e-132 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEFMEDGA_01831 1.3e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEFMEDGA_01832 3.2e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HEFMEDGA_01833 3.2e-261 S Calcineurin-like phosphoesterase
HEFMEDGA_01834 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HEFMEDGA_01835 3e-233 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HEFMEDGA_01836 4.2e-131
HEFMEDGA_01837 0.0 G N-terminal domain of (some) glycogen debranching enzymes
HEFMEDGA_01838 1.6e-49 P Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01839 3.9e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEFMEDGA_01840 2.8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEFMEDGA_01841 5.7e-216 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HEFMEDGA_01842 3e-217 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEFMEDGA_01844 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEFMEDGA_01845 2.5e-164 S Auxin Efflux Carrier
HEFMEDGA_01846 4e-158 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HEFMEDGA_01847 1.5e-119 S Domain of unknown function (DUF4190)
HEFMEDGA_01848 2.7e-163
HEFMEDGA_01849 3e-234 glf 5.4.99.9 M UDP-galactopyranose mutase
HEFMEDGA_01850 1.2e-44 5.3.1.27 G sugar phosphate isomerase involved in capsule formation
HEFMEDGA_01851 2e-59 G Branched-chain amino acid transport system / permease component
HEFMEDGA_01852 5e-73 P branched-chain amino acid ABC transporter, permease protein
HEFMEDGA_01853 6.3e-120 G ATPases associated with a variety of cellular activities
HEFMEDGA_01854 2.1e-79 G ABC-type sugar transport system periplasmic component
HEFMEDGA_01855 3e-167 xylB 1.1.1.57, 2.7.1.17 G Belongs to the FGGY kinase family
HEFMEDGA_01856 1e-75 xylR GK ROK family
HEFMEDGA_01857 3.3e-36
HEFMEDGA_01858 3.2e-200 M Glycosyltransferase like family 2
HEFMEDGA_01859 1.6e-180 S Predicted membrane protein (DUF2142)
HEFMEDGA_01860 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HEFMEDGA_01861 0.0 GT2,GT4 M Glycosyl transferase family 2
HEFMEDGA_01862 1.1e-164 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
HEFMEDGA_01863 1.4e-118 rgpC U Transport permease protein
HEFMEDGA_01864 7.2e-169 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEFMEDGA_01865 1.4e-286 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEFMEDGA_01866 5.5e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEFMEDGA_01867 0.0
HEFMEDGA_01868 8.6e-168 rfbJ M Glycosyl transferase family 2
HEFMEDGA_01869 4.8e-22 M nuclease
HEFMEDGA_01870 3.8e-67 M L,D-transpeptidase catalytic domain
HEFMEDGA_01871 6.7e-166 lytC 3.1.4.46, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HEFMEDGA_01872 3.8e-225 K Cell envelope-related transcriptional attenuator domain
HEFMEDGA_01873 7.5e-256 V ABC transporter permease
HEFMEDGA_01874 8.1e-184 V ABC transporter
HEFMEDGA_01875 3.4e-143 T HD domain
HEFMEDGA_01876 3e-159 S Glutamine amidotransferase domain
HEFMEDGA_01877 0.0 kup P Transport of potassium into the cell
HEFMEDGA_01878 3.1e-186 tatD L TatD related DNase
HEFMEDGA_01879 0.0 yknV V ABC transporter
HEFMEDGA_01880 0.0 mdlA2 V ABC transporter
HEFMEDGA_01881 2.4e-253 S Domain of unknown function (DUF4143)
HEFMEDGA_01882 1e-43 G Glycosyl hydrolases family 43
HEFMEDGA_01883 1.5e-149 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HEFMEDGA_01884 1.6e-84 pepC 3.4.22.40 E Peptidase C1-like family
HEFMEDGA_01885 6.7e-47
HEFMEDGA_01886 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEFMEDGA_01887 2.3e-119
HEFMEDGA_01888 3.1e-184 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEFMEDGA_01890 2.3e-257 G MFS/sugar transport protein
HEFMEDGA_01891 1.3e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEFMEDGA_01892 0.0 lmrA2 V ABC transporter transmembrane region
HEFMEDGA_01893 0.0 lmrA1 V ABC transporter, ATP-binding protein
HEFMEDGA_01894 1.2e-91 ydgJ K helix_turn_helix multiple antibiotic resistance protein
HEFMEDGA_01895 6.1e-277 cycA E Amino acid permease
HEFMEDGA_01896 0.0 V FtsX-like permease family
HEFMEDGA_01897 7.5e-129 V ABC transporter
HEFMEDGA_01898 7e-270 aroP E aromatic amino acid transport protein AroP K03293
HEFMEDGA_01899 1.3e-105 S Protein of unknown function, DUF624
HEFMEDGA_01900 6.8e-153 rafG G ABC transporter permease
HEFMEDGA_01901 4.4e-147 malC G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01902 2.9e-182 K Psort location Cytoplasmic, score
HEFMEDGA_01903 1e-251 amyE G Bacterial extracellular solute-binding protein
HEFMEDGA_01904 1.2e-102 G Phosphoglycerate mutase family
HEFMEDGA_01905 1.2e-59 S Protein of unknown function (DUF4235)
HEFMEDGA_01906 5e-11 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HEFMEDGA_01907 3.7e-96 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HEFMEDGA_01908 0.0 pip S YhgE Pip domain protein
HEFMEDGA_01909 2.4e-280 pip S YhgE Pip domain protein
HEFMEDGA_01910 1.8e-40
HEFMEDGA_01911 9.2e-10
HEFMEDGA_01913 9.2e-10
HEFMEDGA_01914 3.6e-145 cobB2 K Sir2 family
HEFMEDGA_01915 1.5e-231 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HEFMEDGA_01916 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HEFMEDGA_01917 2.9e-154 G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01918 1.1e-143 malC G Binding-protein-dependent transport system inner membrane component
HEFMEDGA_01919 6.8e-245 msmE7 G Bacterial extracellular solute-binding protein
HEFMEDGA_01920 1.2e-230 nagC GK ROK family
HEFMEDGA_01921 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HEFMEDGA_01922 2.2e-78 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEFMEDGA_01923 0.0 yjcE P Sodium/hydrogen exchanger family
HEFMEDGA_01924 2.5e-120 S membrane transporter protein
HEFMEDGA_01925 3.6e-145 ypfH S Phospholipase/Carboxylesterase
HEFMEDGA_01926 2.4e-153
HEFMEDGA_01927 2.2e-110 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HEFMEDGA_01928 2e-37
HEFMEDGA_01929 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HEFMEDGA_01930 2e-16 K helix_turn _helix lactose operon repressor
HEFMEDGA_01931 7.5e-86 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEFMEDGA_01932 1.6e-288 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
HEFMEDGA_01933 3.5e-206 EGP Major facilitator Superfamily
HEFMEDGA_01934 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEFMEDGA_01935 1.6e-168 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
HEFMEDGA_01936 4.6e-301 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HEFMEDGA_01937 6.1e-271 KLT Domain of unknown function (DUF4032)
HEFMEDGA_01938 8.8e-156
HEFMEDGA_01939 7.6e-18 tnp7109-21 L Integrase core domain
HEFMEDGA_01940 1.1e-131 K helix_turn _helix lactose operon repressor
HEFMEDGA_01941 7.1e-146 G Periplasmic binding protein domain
HEFMEDGA_01942 8.7e-178 3.6.3.17 G ATPases associated with a variety of cellular activities
HEFMEDGA_01943 5e-142 U Branched-chain amino acid transport system / permease component
HEFMEDGA_01944 1e-185
HEFMEDGA_01945 1.1e-147 tnp3514b L Winged helix-turn helix
HEFMEDGA_01946 6.2e-48 S LPXTG-motif cell wall anchor domain protein
HEFMEDGA_01947 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
HEFMEDGA_01948 1e-75 K UTRA domain
HEFMEDGA_01949 2.2e-241 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HEFMEDGA_01950 3.7e-45 ulaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HEFMEDGA_01951 2.1e-73 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEFMEDGA_01952 7.8e-216 2.4.1.166 GT2 M Glycosyltransferase like family 2
HEFMEDGA_01953 1.3e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEFMEDGA_01955 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEFMEDGA_01956 5.1e-87 nrdI F Probably involved in ribonucleotide reductase function
HEFMEDGA_01957 3.1e-43 nrdH O Glutaredoxin
HEFMEDGA_01958 2.3e-113 3.2.1.21 GH3 G Fibronectin type III-like domain
HEFMEDGA_01959 0.0 KLT Protein tyrosine kinase
HEFMEDGA_01960 3.6e-137 O Thioredoxin
HEFMEDGA_01962 2e-216 S G5
HEFMEDGA_01963 1.1e-167 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEFMEDGA_01964 4.1e-178 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEFMEDGA_01965 4.8e-111 S LytR cell envelope-related transcriptional attenuator
HEFMEDGA_01966 3.2e-283 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HEFMEDGA_01967 3.4e-164 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HEFMEDGA_01968 0.0
HEFMEDGA_01969 0.0 murJ KLT MviN-like protein
HEFMEDGA_01970 3.1e-176 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEFMEDGA_01971 2.3e-221 parB K Belongs to the ParB family
HEFMEDGA_01972 1.1e-173 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HEFMEDGA_01973 1.5e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HEFMEDGA_01974 1.5e-92 jag S Putative single-stranded nucleic acids-binding domain
HEFMEDGA_01975 5.8e-183 yidC U Membrane protein insertase, YidC Oxa1 family
HEFMEDGA_01976 1.6e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEFMEDGA_01977 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)