ORF_ID e_value Gene_name EC_number CAZy COGs Description
CHALKIFP_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CHALKIFP_00002 8.2e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CHALKIFP_00003 2.7e-28 yyzM S Protein conserved in bacteria
CHALKIFP_00004 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CHALKIFP_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CHALKIFP_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CHALKIFP_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CHALKIFP_00008 2.1e-61 divIC D Septum formation initiator
CHALKIFP_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
CHALKIFP_00011 3.8e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CHALKIFP_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CHALKIFP_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CHALKIFP_00014 1.6e-134 L Transposase
CHALKIFP_00015 9.4e-46 L transposase activity
CHALKIFP_00016 2.5e-22 L Transposase
CHALKIFP_00017 1.2e-55 L transposition
CHALKIFP_00018 2e-88 L Integrase core domain protein
CHALKIFP_00031 5.3e-11
CHALKIFP_00037 8.6e-140 mreC M Involved in formation and maintenance of cell shape
CHALKIFP_00038 2.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CHALKIFP_00039 6.8e-89 usp 3.5.1.28 CBM50 S CHAP domain
CHALKIFP_00040 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHALKIFP_00041 2.9e-218 araT 2.6.1.1 E Aminotransferase
CHALKIFP_00042 7e-144 recO L Involved in DNA repair and RecF pathway recombination
CHALKIFP_00043 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CHALKIFP_00044 1.6e-33 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHALKIFP_00045 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CHALKIFP_00046 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CHALKIFP_00047 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CHALKIFP_00048 3.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CHALKIFP_00049 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CHALKIFP_00050 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CHALKIFP_00051 1e-49 L transposase activity
CHALKIFP_00052 1.7e-51 L transposition
CHALKIFP_00053 1.2e-160 S CHAP domain
CHALKIFP_00054 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
CHALKIFP_00055 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CHALKIFP_00056 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CHALKIFP_00057 9.2e-141 1.1.1.169 H Ketopantoate reductase
CHALKIFP_00058 1.2e-24
CHALKIFP_00059 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CHALKIFP_00060 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CHALKIFP_00061 8.2e-70 argR K Regulates arginine biosynthesis genes
CHALKIFP_00062 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CHALKIFP_00063 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CHALKIFP_00064 6.4e-35 S Protein of unknown function (DUF3021)
CHALKIFP_00065 1.2e-61 KT phosphorelay signal transduction system
CHALKIFP_00067 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CHALKIFP_00069 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CHALKIFP_00070 5.5e-28 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
CHALKIFP_00071 3.8e-232 cinA 3.5.1.42 S Belongs to the CinA family
CHALKIFP_00072 1.1e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CHALKIFP_00073 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
CHALKIFP_00079 2.6e-10
CHALKIFP_00082 1.9e-07
CHALKIFP_00087 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHALKIFP_00088 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CHALKIFP_00089 5.5e-36 XK27_02060 S Transglycosylase associated protein
CHALKIFP_00090 2.6e-55 badR K DNA-binding transcription factor activity
CHALKIFP_00091 3.5e-97 S reductase
CHALKIFP_00092 2e-88 L Integrase core domain protein
CHALKIFP_00093 2.2e-41 L transposition
CHALKIFP_00095 2.1e-76 yocD 3.4.17.13 V carboxypeptidase activity
CHALKIFP_00096 4.6e-91 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
CHALKIFP_00098 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
CHALKIFP_00099 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CHALKIFP_00100 1.1e-83 S Putative small multi-drug export protein
CHALKIFP_00101 2.4e-75 ctsR K Belongs to the CtsR family
CHALKIFP_00102 0.0 clpC O Belongs to the ClpA ClpB family
CHALKIFP_00103 2.4e-101 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CHALKIFP_00104 8.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CHALKIFP_00105 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CHALKIFP_00106 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CHALKIFP_00107 7.7e-143 S SseB protein N-terminal domain
CHALKIFP_00108 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
CHALKIFP_00109 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CHALKIFP_00110 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CHALKIFP_00113 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHALKIFP_00114 7e-92 yacP S RNA-binding protein containing a PIN domain
CHALKIFP_00115 3.4e-155 degV S DegV family
CHALKIFP_00116 1.8e-31 K helix-turn-helix
CHALKIFP_00117 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CHALKIFP_00118 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CHALKIFP_00119 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
CHALKIFP_00120 3.1e-220 L Belongs to the 'phage' integrase family
CHALKIFP_00121 1.2e-83 K Helix-turn-helix
CHALKIFP_00122 1.1e-38
CHALKIFP_00123 8.7e-132 S N-terminal phage replisome organiser (Phage_rep_org_N)
CHALKIFP_00124 4.6e-16
CHALKIFP_00125 3.3e-19
CHALKIFP_00126 2.2e-15
CHALKIFP_00127 5.8e-291 hsdM 2.1.1.72 V type I restriction-modification system
CHALKIFP_00128 4.4e-176 hsdS 3.1.21.3 V COG0732 Restriction endonuclease S subunits
CHALKIFP_00129 6.4e-136 prrC V Anti-codon nuclease
CHALKIFP_00130 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CHALKIFP_00131 2.1e-271 3.6.4.12 K Divergent AAA domain protein
CHALKIFP_00132 8.1e-157 L DEAD-like helicases superfamily
CHALKIFP_00133 0.0 L DEAD-like helicases superfamily
CHALKIFP_00134 9.1e-34 K Peptidase S24-like
CHALKIFP_00136 8.4e-102 S Lantibiotic dehydratase, C terminus
CHALKIFP_00137 0.0 S Lantibiotic dehydratase, C terminus
CHALKIFP_00138 2.4e-231 spaC2 V Lanthionine synthetase C family protein
CHALKIFP_00139 2.5e-183 EGP Major facilitator Superfamily
CHALKIFP_00140 1.6e-91 3.6.4.12 K Divergent AAA domain protein
CHALKIFP_00141 1.4e-50 int L Belongs to the 'phage' integrase family
CHALKIFP_00142 1.3e-27 int L Belongs to the 'phage' integrase family
CHALKIFP_00143 4.4e-13 S Helix-turn-helix domain
CHALKIFP_00145 2.8e-64
CHALKIFP_00146 6.2e-42
CHALKIFP_00147 9.4e-183 L Transposase and inactivated derivatives IS30 family
CHALKIFP_00148 6.8e-76 isp2 S pathogenesis
CHALKIFP_00149 5.7e-91 tnp L Transposase
CHALKIFP_00150 4.6e-42 capA M Bacterial capsule synthesis protein PGA_cap
CHALKIFP_00151 6.7e-87 capA M Bacterial capsule synthesis protein
CHALKIFP_00152 2.5e-13 capA M Bacterial capsule synthesis protein
CHALKIFP_00153 2.8e-57 capA M Bacterial capsule synthesis protein
CHALKIFP_00154 1e-38 gcvR T UPF0237 protein
CHALKIFP_00155 1.7e-243 XK27_08635 S UPF0210 protein
CHALKIFP_00156 3.2e-135 ais G Phosphoglycerate mutase
CHALKIFP_00157 8.8e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CHALKIFP_00158 2.1e-53 acmA 3.2.1.17 NU amidase activity
CHALKIFP_00159 1.4e-40 acmA 3.2.1.17 NU amidase activity
CHALKIFP_00160 2e-197 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CHALKIFP_00161 1.5e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CHALKIFP_00162 7.5e-298 dnaK O Heat shock 70 kDa protein
CHALKIFP_00163 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CHALKIFP_00164 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CHALKIFP_00165 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
CHALKIFP_00166 1.6e-61 hmpT S membrane
CHALKIFP_00179 3.2e-53 bta 1.8.1.8 CO cell redox homeostasis
CHALKIFP_00180 9.1e-10 L thioesterase
CHALKIFP_00181 7.8e-143 S Macro domain protein
CHALKIFP_00182 4.8e-51 trxA O Belongs to the thioredoxin family
CHALKIFP_00183 1.5e-74 yccU S CoA-binding protein
CHALKIFP_00184 1.4e-144 tatD L Hydrolase, tatd
CHALKIFP_00185 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CHALKIFP_00186 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CHALKIFP_00188 1.2e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CHALKIFP_00189 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CHALKIFP_00190 2.4e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
CHALKIFP_00191 6.9e-173 rmuC S RmuC domain protein
CHALKIFP_00192 1.5e-177 cbf S 3'-5' exoribonuclease yhaM
CHALKIFP_00193 2.4e-142 purR 2.4.2.7 F operon repressor
CHALKIFP_00194 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CHALKIFP_00195 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CHALKIFP_00196 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CHALKIFP_00197 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CHALKIFP_00198 4.5e-88 L Integrase core domain protein
CHALKIFP_00199 3.6e-52 L transposition
CHALKIFP_00200 2.5e-22 L Transposase
CHALKIFP_00201 9.4e-46 L transposase activity
CHALKIFP_00202 1.2e-41 L Transposase
CHALKIFP_00203 3.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CHALKIFP_00204 8.7e-38 L Transposase
CHALKIFP_00205 1.3e-87 S Fusaric acid resistance protein-like
CHALKIFP_00206 8.5e-63 glnR K Transcriptional regulator
CHALKIFP_00207 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
CHALKIFP_00208 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CHALKIFP_00209 2.5e-33 ykzG S Belongs to the UPF0356 family
CHALKIFP_00210 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
CHALKIFP_00211 3.7e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CHALKIFP_00212 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CHALKIFP_00213 3.8e-117 azlC E AzlC protein
CHALKIFP_00214 8.8e-48 azlD E branched-chain amino acid
CHALKIFP_00215 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CHALKIFP_00216 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CHALKIFP_00217 1.8e-159 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHALKIFP_00218 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CHALKIFP_00219 3e-93 cvpA S toxin biosynthetic process
CHALKIFP_00220 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CHALKIFP_00221 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CHALKIFP_00224 4.2e-230 mutY L A G-specific adenine glycosylase
CHALKIFP_00225 2.8e-28 XK27_05745
CHALKIFP_00227 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
CHALKIFP_00228 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CHALKIFP_00229 1.4e-34 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CHALKIFP_00231 2e-123 XK27_01040 S Pfam PF06570
CHALKIFP_00232 5.8e-169 corA P COG0598 Mg2 and Co2 transporters
CHALKIFP_00233 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CHALKIFP_00236 4.3e-36 V 'abc transporter, ATP-binding protein
CHALKIFP_00237 1.9e-44 V 'abc transporter, ATP-binding protein
CHALKIFP_00240 4.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
CHALKIFP_00241 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
CHALKIFP_00242 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CHALKIFP_00243 3.4e-62 yqhY S protein conserved in bacteria
CHALKIFP_00244 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CHALKIFP_00245 1.6e-61 scrR K Transcriptional
CHALKIFP_00246 3.7e-100 scrR K Transcriptional
CHALKIFP_00247 4.1e-291 scrB 3.2.1.26 GH32 G invertase
CHALKIFP_00248 0.0 scrA 2.7.1.211 G pts system
CHALKIFP_00249 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
CHALKIFP_00250 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
CHALKIFP_00252 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CHALKIFP_00253 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHALKIFP_00254 4.2e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CHALKIFP_00255 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CHALKIFP_00256 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CHALKIFP_00257 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CHALKIFP_00258 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CHALKIFP_00259 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
CHALKIFP_00260 8.5e-18 yebC M Membrane
CHALKIFP_00261 1.7e-79 yebC M Membrane
CHALKIFP_00262 9.1e-18 KT response to antibiotic
CHALKIFP_00263 6.5e-68 KT response to antibiotic
CHALKIFP_00264 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
CHALKIFP_00265 2.6e-66 liaI S membrane
CHALKIFP_00266 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CHALKIFP_00267 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CHALKIFP_00268 1.6e-11 S Protein of unknown function (DUF554)
CHALKIFP_00269 1.5e-104 S Protein of unknown function (DUF554)
CHALKIFP_00270 2e-45 ecsA_2 V ATPase activity
CHALKIFP_00271 1.1e-89 ecsA_2 V abc transporter atp-binding protein
CHALKIFP_00272 1.3e-285 XK27_00765
CHALKIFP_00273 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CHALKIFP_00274 6.9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CHALKIFP_00275 3.5e-10 D nuclear chromosome segregation
CHALKIFP_00276 1.4e-30 yhaI J Protein of unknown function (DUF805)
CHALKIFP_00277 1.1e-33
CHALKIFP_00278 1.4e-22
CHALKIFP_00279 4e-54
CHALKIFP_00280 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CHALKIFP_00281 5.6e-47 ftsL D cell division protein FtsL
CHALKIFP_00282 0.0 ftsI 3.4.16.4 M penicillin-binding protein
CHALKIFP_00283 3.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CHALKIFP_00284 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CHALKIFP_00286 3.2e-78 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CHALKIFP_00287 1.8e-167 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CHALKIFP_00288 2.3e-72 yutD J protein conserved in bacteria
CHALKIFP_00289 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CHALKIFP_00290 1.5e-92 XK27_09885 V Glycopeptide antibiotics resistance protein
CHALKIFP_00292 0.0 mdlA V abc transporter atp-binding protein
CHALKIFP_00293 0.0 mdlB V abc transporter atp-binding protein
CHALKIFP_00294 2.3e-162 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CHALKIFP_00295 5.2e-215 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CHALKIFP_00296 2.7e-44 mesE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHALKIFP_00297 1.3e-157 mesE M Transport protein ComB
CHALKIFP_00299 1.4e-237 blpH 2.7.13.3 T protein histidine kinase activity
CHALKIFP_00300 2.6e-132 agrA KT phosphorelay signal transduction system
CHALKIFP_00302 3.6e-165 L integrase core domain
CHALKIFP_00303 6.4e-88 L Transposase
CHALKIFP_00305 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CHALKIFP_00306 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
CHALKIFP_00307 9.1e-30 V CAAX protease self-immunity
CHALKIFP_00308 9.4e-183 L Transposase and inactivated derivatives IS30 family
CHALKIFP_00309 4.6e-140 cppA E CppA N-terminal
CHALKIFP_00310 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
CHALKIFP_00311 3.1e-31
CHALKIFP_00312 2.7e-117 ybbL S abc transporter atp-binding protein
CHALKIFP_00313 1.5e-127 ybbM S transport system, permease component
CHALKIFP_00314 7.1e-124 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
CHALKIFP_00315 4.1e-80 L DNA integration
CHALKIFP_00316 3.4e-32 D nuclear chromosome segregation
CHALKIFP_00317 7.1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
CHALKIFP_00318 5.6e-33 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CHALKIFP_00319 8.4e-37 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CHALKIFP_00320 2.2e-122 cah 4.2.1.1 P carbonic anhydrase
CHALKIFP_00321 0.0 pflB 2.3.1.54 C formate acetyltransferase'
CHALKIFP_00322 6.5e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHALKIFP_00324 2.6e-149 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CHALKIFP_00325 2.2e-171 yxeN P ABC transporter (Permease
CHALKIFP_00326 1e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
CHALKIFP_00327 2.8e-08 S Protein of unknown function (DUF4059)
CHALKIFP_00328 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CHALKIFP_00329 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
CHALKIFP_00330 2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CHALKIFP_00331 2.2e-196 ylbL T Belongs to the peptidase S16 family
CHALKIFP_00332 1.3e-184 yhcC S radical SAM protein
CHALKIFP_00333 2.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
CHALKIFP_00335 0.0 yjcE P NhaP-type Na H and K H antiporters
CHALKIFP_00336 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
CHALKIFP_00337 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
CHALKIFP_00338 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHALKIFP_00340 2.4e-75 XK27_03180 T universal stress protein
CHALKIFP_00341 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
CHALKIFP_00342 2.8e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CHALKIFP_00343 6.8e-101 pncA Q isochorismatase
CHALKIFP_00344 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
CHALKIFP_00345 7.9e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHALKIFP_00346 1.2e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CHALKIFP_00347 3.8e-96 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CHALKIFP_00348 7.4e-32 M lipopolysaccharide 3-alpha-galactosyltransferase activity
CHALKIFP_00349 4.4e-25 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
CHALKIFP_00350 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHALKIFP_00351 1.8e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CHALKIFP_00352 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CHALKIFP_00353 1.4e-65
CHALKIFP_00354 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CHALKIFP_00355 1.8e-98 yqeG S hydrolase of the HAD superfamily
CHALKIFP_00356 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CHALKIFP_00357 3.5e-49 yhbY J RNA-binding protein
CHALKIFP_00358 4.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CHALKIFP_00359 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CHALKIFP_00360 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CHALKIFP_00361 7.7e-140 yqeM Q Methyltransferase domain protein
CHALKIFP_00362 1.3e-204 ylbM S Belongs to the UPF0348 family
CHALKIFP_00363 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
CHALKIFP_00364 3.2e-110
CHALKIFP_00365 6.2e-11
CHALKIFP_00366 4.3e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CHALKIFP_00367 2.3e-133 ecsA V abc transporter atp-binding protein
CHALKIFP_00368 3.9e-182 ecsB U ABC transporter
CHALKIFP_00369 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
CHALKIFP_00370 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CHALKIFP_00372 7.7e-227 ytfP S Flavoprotein
CHALKIFP_00373 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CHALKIFP_00374 4.8e-63 XK27_02560 S cog cog2151
CHALKIFP_00375 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
CHALKIFP_00376 3.7e-105 dnaQ 2.7.7.7 L DNA polymerase III
CHALKIFP_00377 9.9e-115 K transcriptional regulator, MerR family
CHALKIFP_00378 1.9e-46 L transposase activity
CHALKIFP_00379 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CHALKIFP_00380 6.1e-27
CHALKIFP_00381 0.0 ctpE P E1-E2 ATPase
CHALKIFP_00382 3.2e-56
CHALKIFP_00383 1.3e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
CHALKIFP_00384 2.9e-112 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHALKIFP_00385 4.2e-124 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CHALKIFP_00386 2.1e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
CHALKIFP_00387 3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CHALKIFP_00388 9.4e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CHALKIFP_00389 1.6e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
CHALKIFP_00390 1.7e-60 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CHALKIFP_00391 6.9e-150 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CHALKIFP_00392 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CHALKIFP_00393 3.2e-74 copY K negative regulation of transcription, DNA-templated
CHALKIFP_00394 0.0 copA 3.6.3.54 P P-type ATPase
CHALKIFP_00395 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
CHALKIFP_00396 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CHALKIFP_00397 6e-115 papP P ABC transporter (Permease
CHALKIFP_00398 7.8e-107 P ABC transporter (Permease
CHALKIFP_00399 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
CHALKIFP_00400 8.8e-156 cjaA ET ABC transporter substrate-binding protein
CHALKIFP_00403 3.6e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CHALKIFP_00404 1.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
CHALKIFP_00405 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CHALKIFP_00406 3.2e-201 yjbB G Permeases of the major facilitator superfamily
CHALKIFP_00407 9.5e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CHALKIFP_00408 7.8e-100 thiT S Thiamine transporter
CHALKIFP_00409 2.5e-62 yjqA S Bacterial PH domain
CHALKIFP_00410 2.3e-154 corA P CorA-like protein
CHALKIFP_00411 4e-255 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CHALKIFP_00412 1e-41 yazA L endonuclease containing a URI domain
CHALKIFP_00413 9.3e-141 yabB 2.1.1.223 L Methyltransferase
CHALKIFP_00414 4.1e-49 nodB3 G polysaccharide deacetylase
CHALKIFP_00415 1.4e-82 nodB3 G polysaccharide deacetylase
CHALKIFP_00416 1.3e-142 plsC 2.3.1.51 I Acyltransferase
CHALKIFP_00417 4e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
CHALKIFP_00418 0.0 comEC S Competence protein ComEC
CHALKIFP_00419 1.2e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHALKIFP_00420 1.8e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
CHALKIFP_00421 1.7e-232 ytoI K transcriptional regulator containing CBS domains
CHALKIFP_00422 5.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
CHALKIFP_00423 6.5e-160 rbn E Belongs to the UPF0761 family
CHALKIFP_00424 1.3e-85 ccl S cog cog4708
CHALKIFP_00425 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CHALKIFP_00426 4.3e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CHALKIFP_00427 5.2e-121 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
CHALKIFP_00428 2.8e-74 S QueT transporter
CHALKIFP_00429 2e-157 xth 3.1.11.2 L exodeoxyribonuclease III
CHALKIFP_00430 2.6e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
CHALKIFP_00431 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CHALKIFP_00432 4.1e-37 ylqC L Belongs to the UPF0109 family
CHALKIFP_00433 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CHALKIFP_00434 0.0 ydaO E amino acid
CHALKIFP_00435 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
CHALKIFP_00436 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CHALKIFP_00437 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
CHALKIFP_00438 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CHALKIFP_00439 5e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CHALKIFP_00440 4.6e-171 murB 1.3.1.98 M cell wall formation
CHALKIFP_00441 3.6e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CHALKIFP_00442 1.4e-139 potB P ABC-type spermidine putrescine transport system, permease component I
CHALKIFP_00443 4.3e-133 potC P ABC-type spermidine putrescine transport system, permease component II
CHALKIFP_00444 2.3e-206 potD P spermidine putrescine ABC transporter
CHALKIFP_00446 1e-115 XK27_08050 O HflC and HflK could regulate a protease
CHALKIFP_00447 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
CHALKIFP_00448 5.4e-116 GK ROK family
CHALKIFP_00449 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CHALKIFP_00450 1.3e-104 wecD M Acetyltransferase (GNAT) domain
CHALKIFP_00451 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CHALKIFP_00452 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
CHALKIFP_00453 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
CHALKIFP_00455 2.2e-58 lrgA S Effector of murein hydrolase LrgA
CHALKIFP_00456 2.2e-117 lrgB M effector of murein hydrolase
CHALKIFP_00457 2.6e-109 3.1.3.18 S IA, variant 1
CHALKIFP_00458 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHALKIFP_00459 3e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CHALKIFP_00460 3.1e-113 serB 3.1.3.3 E phosphoserine phosphatase
CHALKIFP_00462 5.9e-155 EG Permeases of the drug metabolite transporter (DMT) superfamily
CHALKIFP_00463 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
CHALKIFP_00464 1.9e-43 S Domain of unknown function (DUF4299)
CHALKIFP_00465 9.6e-10
CHALKIFP_00466 9.4e-289 V (ABC) transporter
CHALKIFP_00467 8.9e-253 C Arylsulfatase regulator (Fe-S oxidoreductase)
CHALKIFP_00468 2.3e-156 K sequence-specific DNA binding
CHALKIFP_00469 7.7e-52 V Psort location Cytoplasmic, score
CHALKIFP_00470 2.3e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
CHALKIFP_00473 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CHALKIFP_00475 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CHALKIFP_00476 1.1e-16 XK27_00735
CHALKIFP_00477 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
CHALKIFP_00478 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
CHALKIFP_00479 7.6e-32 S CAAX amino terminal protease family protein
CHALKIFP_00480 2.9e-57 V CAAX protease self-immunity
CHALKIFP_00481 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CHALKIFP_00482 2.2e-84 mutT 3.6.1.55 F Nudix family
CHALKIFP_00483 1.3e-143 ET Belongs to the bacterial solute-binding protein 3 family
CHALKIFP_00484 7.2e-136 ET Belongs to the bacterial solute-binding protein 3 family
CHALKIFP_00485 2.8e-202 arcT 2.6.1.1 E Aminotransferase
CHALKIFP_00486 1.4e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
CHALKIFP_00487 6.7e-181 L Transposase and inactivated derivatives IS30 family
CHALKIFP_00488 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CHALKIFP_00489 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CHALKIFP_00490 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CHALKIFP_00491 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
CHALKIFP_00492 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
CHALKIFP_00493 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CHALKIFP_00494 4.4e-220 amrA S membrane protein involved in the export of O-antigen and teichoic acid
CHALKIFP_00495 1.9e-141 M Glycosyltransferase group 2 family protein
CHALKIFP_00496 4.6e-39 arnC M group 2 family protein
CHALKIFP_00497 2.2e-125 ycbB S Glycosyl transferase family 2
CHALKIFP_00498 2.6e-47 XK27_09090 S Uncharacterized conserved protein (DUF2304)
CHALKIFP_00499 1.3e-105 2.4.1.60 S Glycosyltransferase group 2 family protein
CHALKIFP_00500 2.5e-222 rgpA GT4 M Domain of unknown function (DUF1972)
CHALKIFP_00501 1.2e-174 rgpB GT2 M Glycosyltransferase, group 2 family protein
CHALKIFP_00502 8e-143 rgpC GM Transport permease protein
CHALKIFP_00503 8.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CHALKIFP_00504 3.8e-304 GT4 M transferase activity, transferring glycosyl groups
CHALKIFP_00505 0.0 rgpF M Rhamnan synthesis protein F
CHALKIFP_00506 2.5e-267 M Psort location CytoplasmicMembrane, score
CHALKIFP_00507 1.4e-119 radC E Belongs to the UPF0758 family
CHALKIFP_00508 8.8e-130 puuD T peptidase C26
CHALKIFP_00509 8.2e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CHALKIFP_00510 3.1e-59 XK27_04120 S Putative amino acid metabolism
CHALKIFP_00511 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
CHALKIFP_00512 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CHALKIFP_00513 1.5e-103 yjbK S Adenylate cyclase
CHALKIFP_00514 2.1e-120 yjbM 2.7.6.5 S Gtp pyrophosphokinase
CHALKIFP_00515 4e-153 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CHALKIFP_00516 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CHALKIFP_00517 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CHALKIFP_00518 7.4e-39 L transposase activity
CHALKIFP_00519 7.2e-22 L Transposase
CHALKIFP_00520 6e-28 L transposition
CHALKIFP_00521 7.5e-109 L PFAM Integrase catalytic region
CHALKIFP_00522 2.8e-216 oxlT P COG0477 Permeases of the major facilitator superfamily
CHALKIFP_00523 4e-40 tatD L Hydrolase, tatd
CHALKIFP_00524 2e-46 oppF P Belongs to the ABC transporter superfamily
CHALKIFP_00525 1.2e-24 oppF P Belongs to the ABC transporter superfamily
CHALKIFP_00526 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CHALKIFP_00527 1.5e-191 L Transposase
CHALKIFP_00528 4.6e-13 L Transposase
CHALKIFP_00529 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CHALKIFP_00530 2.1e-277 amiC P ABC transporter (Permease
CHALKIFP_00531 4.9e-168 amiD P ABC transporter (Permease
CHALKIFP_00532 2.2e-204 oppD P Belongs to the ABC transporter superfamily
CHALKIFP_00533 4.3e-172 oppF P Belongs to the ABC transporter superfamily
CHALKIFP_00534 3.3e-133 V ATPase activity
CHALKIFP_00535 9.8e-121 skfE V abc transporter atp-binding protein
CHALKIFP_00536 8.6e-63 yvoA_1 K Transcriptional
CHALKIFP_00537 3.1e-147 supH S overlaps another CDS with the same product name
CHALKIFP_00538 3.8e-148 XK27_02985 S overlaps another CDS with the same product name
CHALKIFP_00539 1.8e-219 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CHALKIFP_00540 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CHALKIFP_00541 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
CHALKIFP_00542 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CHALKIFP_00543 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CHALKIFP_00544 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CHALKIFP_00545 5.8e-132 stp 3.1.3.16 T phosphatase
CHALKIFP_00546 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
CHALKIFP_00547 3.7e-120 yvqF KT membrane
CHALKIFP_00548 1.7e-174 vraS 2.7.13.3 T Histidine kinase
CHALKIFP_00549 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CHALKIFP_00552 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CHALKIFP_00553 3.6e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CHALKIFP_00554 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CHALKIFP_00555 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CHALKIFP_00556 2.3e-87 L Transposase
CHALKIFP_00557 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
CHALKIFP_00558 1e-41 V (ABC) transporter
CHALKIFP_00559 1.3e-76 V abc transporter atp-binding protein
CHALKIFP_00560 4.6e-68 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
CHALKIFP_00561 3e-198 M translation initiation factor activity
CHALKIFP_00562 1.2e-25 L transposition
CHALKIFP_00563 7.1e-09 L Integrase core domain protein
CHALKIFP_00564 2.3e-184 galR K Transcriptional regulator
CHALKIFP_00565 3.7e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CHALKIFP_00566 3e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CHALKIFP_00567 3.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CHALKIFP_00568 3.4e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CHALKIFP_00569 0.0 lacS G transporter
CHALKIFP_00570 0.0 lacL 3.2.1.23 G -beta-galactosidase
CHALKIFP_00571 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CHALKIFP_00572 0.0 sbcC L ATPase involved in DNA repair
CHALKIFP_00573 3.8e-21
CHALKIFP_00574 0.0 M family 8
CHALKIFP_00575 2.7e-09
CHALKIFP_00576 5.8e-109 MA20_06410 E LysE type translocator
CHALKIFP_00577 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
CHALKIFP_00578 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
CHALKIFP_00579 4.1e-139
CHALKIFP_00580 1.7e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHALKIFP_00581 5e-60
CHALKIFP_00583 1.1e-69 S Signal peptide protein, YSIRK family
CHALKIFP_00584 2.4e-54 K response regulator
CHALKIFP_00585 9.6e-37 BP1961 P nitric oxide dioxygenase activity
CHALKIFP_00587 4.8e-154 XK27_07020 S Belongs to the UPF0371 family
CHALKIFP_00588 4.9e-119 XK27_07020 S Belongs to the UPF0371 family
CHALKIFP_00589 3.9e-104 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CHALKIFP_00590 4.4e-160 yvgN C reductase
CHALKIFP_00592 3.5e-87 yoaK S Protein of unknown function (DUF1275)
CHALKIFP_00593 2.9e-111 drgA C Nitroreductase
CHALKIFP_00594 2.3e-232 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CHALKIFP_00595 1.9e-158 E Alpha/beta hydrolase of unknown function (DUF915)
CHALKIFP_00596 5.6e-77 ywnA K Transcriptional regulator
CHALKIFP_00597 2.2e-90 1.13.11.2 S glyoxalase
CHALKIFP_00598 2.5e-109 XK27_02070 S nitroreductase
CHALKIFP_00599 6.2e-228 yfnA E amino acid
CHALKIFP_00600 3.7e-25 csbD K CsbD-like
CHALKIFP_00601 2e-49 manA 5.3.1.8 G mannose-6-phosphate isomerase
CHALKIFP_00602 1e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
CHALKIFP_00603 4.3e-234 brnQ E Component of the transport system for branched-chain amino acids
CHALKIFP_00604 3e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CHALKIFP_00605 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
CHALKIFP_00606 3.4e-50 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
CHALKIFP_00607 6.7e-42 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
CHALKIFP_00608 1.1e-148 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
CHALKIFP_00609 3e-115 yxeQ S MmgE/PrpD family
CHALKIFP_00610 5.4e-58 yxeL K Acetyltransferase (GNAT) domain
CHALKIFP_00611 2e-65 yxeN U ABC transporter, permease protein
CHALKIFP_00612 7.3e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
CHALKIFP_00613 2.9e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
CHALKIFP_00614 2.9e-84 yxeM ET Belongs to the bacterial solute-binding protein 3 family
CHALKIFP_00615 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CHALKIFP_00616 2.9e-246 norM V Multidrug efflux pump
CHALKIFP_00617 3.9e-122 L Transposase
CHALKIFP_00618 3.6e-165 L integrase core domain
CHALKIFP_00619 7.1e-125 pbuX F xanthine permease
CHALKIFP_00620 1.4e-74 pbuX F xanthine permease
CHALKIFP_00621 7.8e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CHALKIFP_00622 2e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CHALKIFP_00623 2.1e-166 T Histidine kinase
CHALKIFP_00624 1.9e-133 macB2 V ABC transporter, ATP-binding protein
CHALKIFP_00625 0.0 V ABC transporter (permease)
CHALKIFP_00626 2.9e-34 XK27_05000 S metal cluster binding
CHALKIFP_00627 2.4e-80 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
CHALKIFP_00628 1.8e-165 yocS S Transporter
CHALKIFP_00631 2.3e-159 XK27_09825 V abc transporter atp-binding protein
CHALKIFP_00632 4.8e-134 yvfS V ABC-2 type transporter
CHALKIFP_00633 2.5e-187 desK 2.7.13.3 T Histidine kinase
CHALKIFP_00634 6.1e-103 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CHALKIFP_00635 6.6e-99 S transport system, permease component
CHALKIFP_00636 2.9e-145 S ABC-2 family transporter protein
CHALKIFP_00637 3.3e-26
CHALKIFP_00638 1.6e-149 sdaAA 4.3.1.17 E L-serine dehydratase
CHALKIFP_00639 2.5e-121 sdaAB 4.3.1.17 E L-serine dehydratase
CHALKIFP_00640 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CHALKIFP_00641 5.4e-206 S Protein of unknown function (DUF917)
CHALKIFP_00642 1.4e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
CHALKIFP_00643 1.7e-111 proWZ P ABC transporter (Permease
CHALKIFP_00644 2e-169 proX M ABC transporter, substrate-binding protein, QAT family
CHALKIFP_00645 1.5e-138 proV E abc transporter atp-binding protein
CHALKIFP_00646 3.6e-90 proW P Binding-protein-dependent transport system inner membrane component
CHALKIFP_00647 8.9e-64 bioY S biotin transmembrane transporter activity
CHALKIFP_00648 8.2e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
CHALKIFP_00649 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CHALKIFP_00650 7.3e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CHALKIFP_00651 1.6e-91 pat 2.3.1.183 M acetyltransferase
CHALKIFP_00652 2.6e-88 alkD L Dna alkylation repair
CHALKIFP_00653 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CHALKIFP_00654 3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CHALKIFP_00655 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CHALKIFP_00656 0.0 smc D Required for chromosome condensation and partitioning
CHALKIFP_00657 3.3e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CHALKIFP_00658 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CHALKIFP_00659 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CHALKIFP_00662 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
CHALKIFP_00663 4.2e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CHALKIFP_00665 2e-86 S ECF-type riboflavin transporter, S component
CHALKIFP_00666 5.5e-155 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
CHALKIFP_00667 5.4e-09 XK27_01265 S ECF-type riboflavin transporter, S component
CHALKIFP_00668 5.4e-46 XK27_01265 S ECF-type riboflavin transporter, S component
CHALKIFP_00669 2.8e-293 yfmM S abc transporter atp-binding protein
CHALKIFP_00670 2.6e-258 noxE P NADH oxidase
CHALKIFP_00671 3.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CHALKIFP_00672 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CHALKIFP_00673 4.3e-59 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
CHALKIFP_00674 4.6e-58 srtA 3.4.22.70 M Sortase family
CHALKIFP_00675 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
CHALKIFP_00676 1.8e-165 ypuA S secreted protein
CHALKIFP_00677 5.5e-65 L Transposase (IS116 IS110 IS902 family)
CHALKIFP_00678 1.1e-74 L Transposase (IS116 IS110 IS902 family)
CHALKIFP_00680 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHALKIFP_00681 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CHALKIFP_00682 2.2e-34 nrdH O Glutaredoxin
CHALKIFP_00683 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CHALKIFP_00684 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
CHALKIFP_00685 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
CHALKIFP_00686 7.9e-39 ptsH G phosphocarrier protein Hpr
CHALKIFP_00687 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CHALKIFP_00688 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
CHALKIFP_00689 2.4e-19 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CHALKIFP_00690 1.2e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
CHALKIFP_00691 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
CHALKIFP_00692 0.0 uup S abc transporter atp-binding protein
CHALKIFP_00693 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
CHALKIFP_00694 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CHALKIFP_00695 8.7e-150 cobQ S glutamine amidotransferase
CHALKIFP_00696 8.3e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
CHALKIFP_00697 1.2e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CHALKIFP_00698 1e-168 ybbR S Protein conserved in bacteria
CHALKIFP_00699 1.6e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CHALKIFP_00700 1.1e-69 gtrA S GtrA-like protein
CHALKIFP_00701 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
CHALKIFP_00702 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CHALKIFP_00703 7e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
CHALKIFP_00704 1.7e-100 zupT P Mediates zinc uptake. May also transport other divalent cations
CHALKIFP_00705 4.8e-207 yurR 1.4.5.1 E oxidoreductase
CHALKIFP_00706 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CHALKIFP_00707 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CHALKIFP_00708 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CHALKIFP_00712 2.9e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
CHALKIFP_00713 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
CHALKIFP_00714 1.7e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CHALKIFP_00715 1.8e-121 ylfI S tigr01906
CHALKIFP_00716 2.2e-139 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
CHALKIFP_00717 1.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
CHALKIFP_00718 4.4e-68 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
CHALKIFP_00719 6.2e-239 rodA D Belongs to the SEDS family
CHALKIFP_00720 4.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CHALKIFP_00721 7.9e-117 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CHALKIFP_00722 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CHALKIFP_00723 3e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CHALKIFP_00724 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
CHALKIFP_00725 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CHALKIFP_00726 3.5e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CHALKIFP_00727 2.9e-125 dnaD
CHALKIFP_00728 1.3e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CHALKIFP_00731 3.4e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CHALKIFP_00732 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
CHALKIFP_00733 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CHALKIFP_00734 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CHALKIFP_00735 7.5e-74 argR K arginine binding
CHALKIFP_00736 1.3e-304 recN L May be involved in recombinational repair of damaged DNA
CHALKIFP_00737 1.7e-148 DegV S DegV family
CHALKIFP_00738 3.8e-146 ypmR E lipolytic protein G-D-S-L family
CHALKIFP_00739 6.8e-96 ypmS S Protein conserved in bacteria
CHALKIFP_00740 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CHALKIFP_00742 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
CHALKIFP_00743 9.7e-41 L Transposase and inactivated derivatives IS30 family
CHALKIFP_00744 1.8e-127 L Transposase and inactivated derivatives IS30 family
CHALKIFP_00745 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CHALKIFP_00746 7.6e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CHALKIFP_00747 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CHALKIFP_00748 1.1e-41 ysdA L Membrane
CHALKIFP_00749 8.9e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHALKIFP_00750 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CHALKIFP_00751 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
CHALKIFP_00752 0.0 dnaE 2.7.7.7 L DNA polymerase
CHALKIFP_00753 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CHALKIFP_00754 3.9e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CHALKIFP_00756 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
CHALKIFP_00758 5.4e-27 Q the current gene model (or a revised gene model) may contain a frame shift
CHALKIFP_00759 9.6e-43 Q the current gene model (or a revised gene model) may contain a frame shift
CHALKIFP_00761 3.2e-17 S Domain of unknown function (DUF4649)
CHALKIFP_00762 3.1e-176 XK27_08835 S ABC transporter substrate binding protein
CHALKIFP_00763 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
CHALKIFP_00764 5.8e-135 XK27_08845 S abc transporter atp-binding protein
CHALKIFP_00765 3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CHALKIFP_00766 3.5e-151 estA CE1 S Putative esterase
CHALKIFP_00767 1e-125 XK27_08875 O Zinc-dependent metalloprotease
CHALKIFP_00768 2.5e-14 XK27_08880
CHALKIFP_00769 5.1e-75 fld C Flavodoxin
CHALKIFP_00770 1.1e-281 clcA P Chloride transporter, ClC family
CHALKIFP_00771 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
CHALKIFP_00772 1.4e-218 XK27_05110 P chloride
CHALKIFP_00773 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CHALKIFP_00776 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
CHALKIFP_00777 6.4e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CHALKIFP_00778 2.1e-88 ytsP 1.8.4.14 T GAF domain-containing protein
CHALKIFP_00779 1.2e-294 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CHALKIFP_00781 1.7e-173 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CHALKIFP_00782 1.3e-202 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CHALKIFP_00783 7e-27 G Domain of unknown function (DUF4832)
CHALKIFP_00784 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CHALKIFP_00785 2.6e-09 S Protein of unknown function (DUF1146)
CHALKIFP_00786 5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHALKIFP_00787 1.6e-25 epuA S DNA-directed RNA polymerase subunit beta
CHALKIFP_00788 2e-142 endA F DNA RNA non-specific endonuclease
CHALKIFP_00789 1.7e-111 tcyB_2 P ABC transporter (permease)
CHALKIFP_00790 2.7e-118 gltJ P ABC transporter (Permease
CHALKIFP_00791 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CHALKIFP_00792 4.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
CHALKIFP_00793 5.4e-127 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CHALKIFP_00794 1.5e-234 vicK 2.7.13.3 T Histidine kinase
CHALKIFP_00795 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
CHALKIFP_00796 2e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
CHALKIFP_00797 9.2e-147 yidA S hydrolases of the HAD superfamily
CHALKIFP_00798 1.7e-51 XK27_00115 2.3.1.128 K acetyltransferase
CHALKIFP_00799 2.6e-67 ywiB S Domain of unknown function (DUF1934)
CHALKIFP_00800 0.0 pacL 3.6.3.8 P cation transport ATPase
CHALKIFP_00801 6.7e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CHALKIFP_00802 1.3e-181 yjjH S Calcineurin-like phosphoesterase
CHALKIFP_00803 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CHALKIFP_00804 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CHALKIFP_00805 3.2e-124 ftsE D cell division ATP-binding protein FtsE
CHALKIFP_00806 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CHALKIFP_00807 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
CHALKIFP_00808 6.2e-176 yubA S permease
CHALKIFP_00809 4.9e-224 G COG0457 FOG TPR repeat
CHALKIFP_00810 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CHALKIFP_00811 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CHALKIFP_00812 1.9e-89 ebsA S Family of unknown function (DUF5322)
CHALKIFP_00813 8.2e-18 M LysM domain
CHALKIFP_00814 1.1e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CHALKIFP_00815 9.8e-89 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CHALKIFP_00816 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CHALKIFP_00817 7.4e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CHALKIFP_00818 5.8e-42 L Transposase
CHALKIFP_00819 1.6e-24 L Transposase
CHALKIFP_00820 6.9e-86 XK27_03610 K Gnat family
CHALKIFP_00821 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CHALKIFP_00822 2.4e-275 pepV 3.5.1.18 E Dipeptidase
CHALKIFP_00823 3.4e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
CHALKIFP_00824 3e-32 V Glucan-binding protein C
CHALKIFP_00825 5.7e-08 V Glucan-binding protein C
CHALKIFP_00826 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CHALKIFP_00827 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CHALKIFP_00828 2.9e-88 S Protein of unknown function (DUF1697)
CHALKIFP_00829 6.8e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CHALKIFP_00830 3.1e-93 yfeJ 6.3.5.2 F glutamine amidotransferase
CHALKIFP_00831 3.1e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
CHALKIFP_00832 5.9e-245 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
CHALKIFP_00833 1.9e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
CHALKIFP_00834 2.2e-96 cps4C M biosynthesis protein
CHALKIFP_00835 9.5e-114 cpsD D COG0489 ATPases involved in chromosome partitioning
CHALKIFP_00836 4e-58 rfbP 2.7.8.6 M Bacterial sugar transferase
CHALKIFP_00838 2.9e-83 M Glycosyl transferase 4-like
CHALKIFP_00839 2.3e-63 2.4.1.21 GT4,GT5 G Glycosyl transferase 4-like domain
CHALKIFP_00840 9e-33 epsH S Hexapeptide repeat of succinyl-transferase
CHALKIFP_00841 2.3e-59 S Glycosyltransferase like family 2
CHALKIFP_00842 1.2e-32 S EpsG family
CHALKIFP_00844 4e-24 H Core-2/I-Branching enzyme
CHALKIFP_00845 2e-52 yxaB GM Polysaccharide pyruvyl transferase
CHALKIFP_00846 4e-105 cps2J S Polysaccharide biosynthesis protein
CHALKIFP_00847 5.6e-90 V VanZ like family
CHALKIFP_00848 3.2e-08 tnp L DDE domain
CHALKIFP_00849 2.3e-67 tnp L DDE domain
CHALKIFP_00850 1.6e-58 waaB GT4 M Glycosyl transferases group 1
CHALKIFP_00851 2.5e-222 L Transposase, Mutator family
CHALKIFP_00852 1.9e-68 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
CHALKIFP_00853 1.4e-87 G Belongs to the phosphoglycerate mutase family
CHALKIFP_00854 7.7e-200 S hmm pf01594
CHALKIFP_00855 4.1e-29 bglH 3.2.1.86 GT1 G beta-glucosidase activity
CHALKIFP_00856 5.1e-101 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CHALKIFP_00857 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
CHALKIFP_00858 1.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CHALKIFP_00859 1.3e-39 S granule-associated protein
CHALKIFP_00860 5.2e-295 S unusual protein kinase
CHALKIFP_00861 4.6e-85 estA E GDSL-like protein
CHALKIFP_00862 4.9e-159 rssA S Phospholipase, patatin family
CHALKIFP_00863 5.3e-178 3.4.16.4 M Belongs to the peptidase S11 family
CHALKIFP_00864 2.4e-23 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
CHALKIFP_00865 2e-129 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHALKIFP_00866 5e-20 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHALKIFP_00867 3.3e-34 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CHALKIFP_00868 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CHALKIFP_00869 2.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CHALKIFP_00870 9.7e-65 S the current gene model (or a revised gene model) may contain a frame shift
CHALKIFP_00871 4.6e-38 P membrane protein (DUF2207)
CHALKIFP_00872 1.7e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
CHALKIFP_00873 8.3e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CHALKIFP_00874 2.1e-199 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CHALKIFP_00875 0.0 lpdA 1.8.1.4 C Dehydrogenase
CHALKIFP_00876 2.8e-19 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CHALKIFP_00877 3.8e-69 3.2.1.17 M lysozyme activity
CHALKIFP_00878 4.6e-238 L Transposase
CHALKIFP_00879 2.7e-123 K Transcriptional activator, Rgg GadR MutR family
CHALKIFP_00880 3.2e-172 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHALKIFP_00881 2e-103 L nUDIX hydrolase
CHALKIFP_00882 3.2e-19 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CHALKIFP_00884 1.1e-26 fic D Fic/DOC family
CHALKIFP_00885 1.6e-25
CHALKIFP_00886 3.4e-149 L Transposase
CHALKIFP_00887 4.1e-53 L Transposase
CHALKIFP_00888 1.2e-222 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CHALKIFP_00889 5.5e-36 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CHALKIFP_00890 1.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHALKIFP_00891 1.5e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CHALKIFP_00892 2e-132 yclP 3.6.3.34 P abc transporter atp-binding protein
CHALKIFP_00893 5.2e-87 fatB P ABC-type enterochelin transport system, periplasmic component
CHALKIFP_00895 2.1e-21 ycdO P periplasmic lipoprotein involved in iron transport
CHALKIFP_00896 2.2e-12 ycdO P periplasmic lipoprotein involved in iron transport
CHALKIFP_00897 1.5e-233 ycdB P peroxidase
CHALKIFP_00898 2.9e-304 ywbL P COG0672 High-affinity Fe2 Pb2 permease
CHALKIFP_00899 2e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CHALKIFP_00900 4.6e-25 tatA U protein secretion
CHALKIFP_00901 1.3e-46 malF P ABC transporter (Permease
CHALKIFP_00902 2.6e-53 malF P ABC transporter (Permease
CHALKIFP_00903 2.3e-27 malX G maltose binding
CHALKIFP_00904 3.8e-12 malX G maltose binding
CHALKIFP_00905 3.2e-17 malX G ABC transporter
CHALKIFP_00906 8.1e-177 malR K Transcriptional regulator
CHALKIFP_00907 4.1e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
CHALKIFP_00908 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CHALKIFP_00909 3.2e-08
CHALKIFP_00910 1.2e-07
CHALKIFP_00911 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
CHALKIFP_00913 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
CHALKIFP_00914 0.0 pepN 3.4.11.2 E aminopeptidase
CHALKIFP_00915 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
CHALKIFP_00916 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CHALKIFP_00917 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CHALKIFP_00918 1.2e-155 pstA P phosphate transport system permease
CHALKIFP_00919 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
CHALKIFP_00920 5.6e-158 pstS P phosphate
CHALKIFP_00921 9.7e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
CHALKIFP_00922 6.5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
CHALKIFP_00923 2.3e-44 yktA S Belongs to the UPF0223 family
CHALKIFP_00924 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CHALKIFP_00925 1.7e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CHALKIFP_00926 4.2e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CHALKIFP_00927 3.4e-212 XK27_04775 S hemerythrin HHE cation binding domain
CHALKIFP_00928 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
CHALKIFP_00929 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CHALKIFP_00930 9.3e-62 S haloacid dehalogenase-like hydrolase
CHALKIFP_00931 1.8e-59 Q phosphatase activity
CHALKIFP_00932 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
CHALKIFP_00933 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CHALKIFP_00934 4e-240 agcS E (Alanine) symporter
CHALKIFP_00935 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CHALKIFP_00936 1e-22 bglC K Transcriptional regulator
CHALKIFP_00937 5.9e-103 yfiF3 K sequence-specific DNA binding
CHALKIFP_00938 1.9e-38 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
CHALKIFP_00939 2.6e-272 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
CHALKIFP_00941 9.2e-22 yecS P amino acid transport
CHALKIFP_00942 3.3e-68 yecS P ABC transporter (Permease
CHALKIFP_00943 3.2e-59 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
CHALKIFP_00944 4.6e-73 yckB ET Belongs to the bacterial solute-binding protein 3 family
CHALKIFP_00945 2.2e-106 nylA 3.5.1.4 J Belongs to the amidase family
CHALKIFP_00946 9.4e-183 L Transposase and inactivated derivatives IS30 family
CHALKIFP_00947 6.5e-268 dtpT E transporter
CHALKIFP_00948 9.3e-55 nylA 3.5.1.4 J Belongs to the amidase family
CHALKIFP_00950 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CHALKIFP_00951 3.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CHALKIFP_00952 6.5e-89 csm6 S Psort location Cytoplasmic, score
CHALKIFP_00953 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
CHALKIFP_00954 2.6e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
CHALKIFP_00955 1.6e-117 csm3 L RAMP superfamily
CHALKIFP_00956 5.6e-62 csm2 L Pfam:DUF310
CHALKIFP_00957 0.0 csm1 S CRISPR-associated protein Csm1 family
CHALKIFP_00958 6.8e-133 cas6 S Pfam:DUF2276
CHALKIFP_00959 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CHALKIFP_00960 2.2e-69 cas1 L maintenance of DNA repeat elements
CHALKIFP_00961 2.8e-111 cas1 L maintenance of DNA repeat elements
CHALKIFP_00962 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CHALKIFP_00963 1.5e-149 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CHALKIFP_00964 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
CHALKIFP_00965 9.7e-89 S TraX protein
CHALKIFP_00967 2.1e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
CHALKIFP_00969 4.2e-75 dinF V Mate efflux family protein
CHALKIFP_00970 1.2e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
CHALKIFP_00971 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
CHALKIFP_00972 9.8e-120 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
CHALKIFP_00973 6.9e-144 2.4.2.3 F Phosphorylase superfamily
CHALKIFP_00976 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
CHALKIFP_00977 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
CHALKIFP_00978 6e-08 S Hydrolases of the alpha beta superfamily
CHALKIFP_00979 8.1e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
CHALKIFP_00980 6.7e-144 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CHALKIFP_00981 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CHALKIFP_00982 2.3e-159 czcD P cation diffusion facilitator family transporter
CHALKIFP_00983 6.9e-98 K Transcriptional regulator, TetR family
CHALKIFP_00984 1.6e-10
CHALKIFP_00985 3.5e-113 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CHALKIFP_00986 5.9e-116 V ABC transporter (Permease
CHALKIFP_00987 4.6e-13 L Transposase
CHALKIFP_00988 3.1e-133 L Transposase
CHALKIFP_00989 1.9e-13
CHALKIFP_00990 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
CHALKIFP_00991 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CHALKIFP_00992 6.6e-61 EGP Major facilitator Superfamily
CHALKIFP_00993 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
CHALKIFP_00994 1.3e-212 pqqE C radical SAM domain protein
CHALKIFP_00997 2.6e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CHALKIFP_00998 1.1e-53 K peptidyl-tyrosine sulfation
CHALKIFP_01002 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CHALKIFP_01003 3.9e-19 IQ Acetoin reductase
CHALKIFP_01004 6.6e-54 IQ Acetoin reductase
CHALKIFP_01005 6e-90 ET Bacterial periplasmic substrate-binding proteins
CHALKIFP_01006 7.3e-46 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHALKIFP_01007 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CHALKIFP_01008 2e-154 XK27_05470 E Methionine synthase
CHALKIFP_01009 2.5e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CHALKIFP_01010 5.3e-251 T PhoQ Sensor
CHALKIFP_01011 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CHALKIFP_01012 6.7e-153 S TraX protein
CHALKIFP_01013 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CHALKIFP_01014 2.4e-158 dprA LU DNA protecting protein DprA
CHALKIFP_01015 3.7e-168 GK ROK family
CHALKIFP_01016 2.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CHALKIFP_01017 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CHALKIFP_01018 5.6e-129 K DNA-binding helix-turn-helix protein
CHALKIFP_01019 6e-91 niaR S small molecule binding protein (contains 3H domain)
CHALKIFP_01020 3.1e-87 niaX
CHALKIFP_01021 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CHALKIFP_01022 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CHALKIFP_01023 1.6e-126 gntR1 K transcriptional
CHALKIFP_01024 1.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CHALKIFP_01025 1.7e-93 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
CHALKIFP_01026 1.2e-263 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
CHALKIFP_01027 0.0 res_1 3.1.21.5 S Type III restriction
CHALKIFP_01028 2.7e-22
CHALKIFP_01029 2.4e-81 adhP 1.1.1.1 C alcohol dehydrogenase
CHALKIFP_01030 1.8e-15 adhP 1.1.1.1 P alcohol dehydrogenase
CHALKIFP_01031 4.6e-63 adhP 1.1.1.1 C alcohol dehydrogenase
CHALKIFP_01032 7.8e-25
CHALKIFP_01033 2.1e-07
CHALKIFP_01034 5.8e-149 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CHALKIFP_01035 8.4e-159 aatB ET ABC transporter substrate-binding protein
CHALKIFP_01036 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
CHALKIFP_01037 2.4e-105 artQ P ABC transporter (Permease
CHALKIFP_01038 5.6e-58 phnA P Alkylphosphonate utilization operon protein PhnA
CHALKIFP_01039 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CHALKIFP_01040 2.6e-166 cpsY K Transcriptional regulator
CHALKIFP_01041 1.3e-97 L transposition
CHALKIFP_01042 7.1e-114 mur1 NU muramidase
CHALKIFP_01043 1e-171 yeiH S Membrane
CHALKIFP_01044 7.1e-17
CHALKIFP_01045 2.5e-46
CHALKIFP_01046 1.4e-109 L Transposase
CHALKIFP_01048 1.7e-08
CHALKIFP_01049 2.3e-295 adcA P Belongs to the bacterial solute-binding protein 9 family
CHALKIFP_01050 2.5e-110 XK27_10720 D peptidase activity
CHALKIFP_01051 2.9e-78 hsdM 2.1.1.72 V HsdM N-terminal domain
CHALKIFP_01052 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
CHALKIFP_01053 5.7e-133 glcU U Glucose uptake
CHALKIFP_01054 7.3e-33 hsdM 2.1.1.72 V type I restriction-modification system
CHALKIFP_01055 1.7e-63 hsdM 2.1.1.72 V type I restriction-modification system
CHALKIFP_01056 1.6e-57 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
CHALKIFP_01057 2.6e-222 L Transposase
CHALKIFP_01058 5.2e-62 cysE 2.3.1.30 E serine acetyltransferase
CHALKIFP_01059 2e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CHALKIFP_01060 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CHALKIFP_01061 1.4e-195 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CHALKIFP_01062 8.5e-218 L Transposase
CHALKIFP_01063 3.1e-08 copB 3.6.3.4 P COG2217 Cation transport ATPase
CHALKIFP_01064 4.1e-306 copB 3.6.3.4 P P-type ATPase
CHALKIFP_01065 3.6e-224 L Transposase, Mutator family
CHALKIFP_01066 9.4e-43 K Cold-Shock Protein
CHALKIFP_01067 5.4e-32 cspD K Cold shock protein domain
CHALKIFP_01068 5.8e-41 pepD E dipeptidase activity
CHALKIFP_01069 2.8e-90 pepD E Dipeptidase
CHALKIFP_01070 8.7e-162 whiA K May be required for sporulation
CHALKIFP_01071 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CHALKIFP_01072 1.2e-163 rapZ S Displays ATPase and GTPase activities
CHALKIFP_01073 7.4e-138 yejC S cyclic nucleotide-binding protein
CHALKIFP_01074 7.7e-20 D nuclear chromosome segregation
CHALKIFP_01075 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
CHALKIFP_01076 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CHALKIFP_01077 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
CHALKIFP_01078 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CHALKIFP_01079 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
CHALKIFP_01080 8.1e-08
CHALKIFP_01082 4.9e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CHALKIFP_01083 1.9e-217 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CHALKIFP_01084 6.8e-81 ypmB S Protein conserved in bacteria
CHALKIFP_01085 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CHALKIFP_01086 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CHALKIFP_01087 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
CHALKIFP_01088 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
CHALKIFP_01089 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CHALKIFP_01090 7.3e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
CHALKIFP_01091 4.7e-57 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CHALKIFP_01092 4.8e-64 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CHALKIFP_01093 6e-21 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CHALKIFP_01094 8.6e-65 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
CHALKIFP_01095 4.5e-59 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
CHALKIFP_01096 1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
CHALKIFP_01097 6.9e-26 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
CHALKIFP_01098 2.3e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
CHALKIFP_01099 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
CHALKIFP_01100 2.1e-30 rpsT J rRNA binding
CHALKIFP_01101 1.9e-127 T PhoQ Sensor
CHALKIFP_01102 1.7e-43 T PhoQ Sensor
CHALKIFP_01103 4.3e-41 T PhoQ Sensor
CHALKIFP_01104 1.1e-84 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CHALKIFP_01105 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CHALKIFP_01106 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
CHALKIFP_01107 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CHALKIFP_01108 1.4e-93 panT S ECF transporter, substrate-specific component
CHALKIFP_01109 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CHALKIFP_01110 7.3e-166 metF 1.5.1.20 C reductase
CHALKIFP_01111 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CHALKIFP_01113 1.5e-219 sip L Belongs to the 'phage' integrase family
CHALKIFP_01114 5.1e-43 K Transcriptional
CHALKIFP_01115 8e-20 K TRANSCRIPTIONal
CHALKIFP_01119 1.4e-13
CHALKIFP_01120 3.1e-22
CHALKIFP_01121 5.6e-142 KL Phage plasmid primase P4 family
CHALKIFP_01122 4.8e-282 S DNA primase
CHALKIFP_01124 2.9e-12
CHALKIFP_01126 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
CHALKIFP_01127 0.0 3.6.3.8 P cation transport ATPase
CHALKIFP_01128 3.4e-19 L transposase activity
CHALKIFP_01129 9.3e-53 L transposition
CHALKIFP_01130 3.6e-31 L Integrase core domain protein
CHALKIFP_01131 6.3e-34 L Integrase core domain protein
CHALKIFP_01132 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CHALKIFP_01133 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CHALKIFP_01134 4.6e-238 dltB M Membrane protein involved in D-alanine export
CHALKIFP_01135 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CHALKIFP_01136 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
CHALKIFP_01137 0.0 XK27_10035 V abc transporter atp-binding protein
CHALKIFP_01138 0.0 yfiB1 V abc transporter atp-binding protein
CHALKIFP_01139 2.4e-107 pvaA M lytic transglycosylase activity
CHALKIFP_01140 2.7e-123 ndpA S 37-kD nucleoid-associated bacterial protein
CHALKIFP_01141 2e-36 ndpA S 37-kD nucleoid-associated bacterial protein
CHALKIFP_01142 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CHALKIFP_01143 1.1e-107 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CHALKIFP_01144 4e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CHALKIFP_01145 5.1e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CHALKIFP_01146 4.5e-111 tdk 2.7.1.21 F thymidine kinase
CHALKIFP_01147 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CHALKIFP_01148 2e-154 gst O Glutathione S-transferase
CHALKIFP_01149 1.5e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
CHALKIFP_01150 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CHALKIFP_01151 2e-45 rpmE2 J 50S ribosomal protein L31
CHALKIFP_01152 1e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
CHALKIFP_01153 8.4e-10
CHALKIFP_01154 1.2e-17
CHALKIFP_01155 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CHALKIFP_01156 7.9e-136 divIVA D Cell division protein DivIVA
CHALKIFP_01157 7.2e-144 ylmH T S4 RNA-binding domain
CHALKIFP_01158 8.8e-35 yggT D integral membrane protein
CHALKIFP_01159 2.3e-96 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CHALKIFP_01160 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CHALKIFP_01161 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CHALKIFP_01162 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CHALKIFP_01163 2.2e-178 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CHALKIFP_01164 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CHALKIFP_01165 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CHALKIFP_01167 0.0 typA T GTP-binding protein TypA
CHALKIFP_01168 2.2e-179 glk 2.7.1.2 G Glucokinase
CHALKIFP_01169 8.4e-28 yqgQ S protein conserved in bacteria
CHALKIFP_01170 1.1e-80 perR P Belongs to the Fur family
CHALKIFP_01171 6e-91 dps P Belongs to the Dps family
CHALKIFP_01172 3e-116 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
CHALKIFP_01173 1.4e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
CHALKIFP_01174 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
CHALKIFP_01175 7.1e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
CHALKIFP_01176 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CHALKIFP_01177 6.2e-56 S Domain of unknown function (DUF4430)
CHALKIFP_01178 1.2e-74 S Psort location CytoplasmicMembrane, score
CHALKIFP_01179 5.4e-132 htpX O Belongs to the peptidase M48B family
CHALKIFP_01180 3.4e-92 lemA S LemA family
CHALKIFP_01181 1.7e-174 spd F DNA RNA non-specific endonuclease
CHALKIFP_01182 4.3e-50 S PD-(D/E)XK nuclease family transposase
CHALKIFP_01183 2.4e-303 hsdM 2.1.1.72 V type I restriction-modification system
CHALKIFP_01184 1.2e-135 S Protein conserved in bacteria
CHALKIFP_01185 4.8e-105
CHALKIFP_01186 2.4e-122 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
CHALKIFP_01187 9.4e-190
CHALKIFP_01188 2.2e-258
CHALKIFP_01189 1.4e-14
CHALKIFP_01190 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CHALKIFP_01191 1.6e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CHALKIFP_01192 2.7e-37 MA20_36090 S Protein of unknown function (DUF2974)
CHALKIFP_01193 2.3e-10 MA20_36090 S Protein of unknown function (DUF2974)
CHALKIFP_01194 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CHALKIFP_01195 2.7e-27 P Hemerythrin HHE cation binding domain protein
CHALKIFP_01196 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
CHALKIFP_01197 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CHALKIFP_01198 5.1e-116 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
CHALKIFP_01199 2.3e-175 S hydrolase
CHALKIFP_01200 5.9e-16
CHALKIFP_01201 2.1e-42 M LysM domain
CHALKIFP_01202 3.5e-52 M LysM domain
CHALKIFP_01203 3.4e-22 M LysM domain
CHALKIFP_01204 2.2e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CHALKIFP_01205 1.8e-127 L Transposase and inactivated derivatives IS30 family
CHALKIFP_01206 9.7e-41 L Transposase and inactivated derivatives IS30 family
CHALKIFP_01207 1.3e-25
CHALKIFP_01208 7.8e-19 pvuIIC K Helix-turn-helix domain
CHALKIFP_01212 6.3e-38
CHALKIFP_01213 2.1e-39
CHALKIFP_01214 1.5e-100 L helicase
CHALKIFP_01215 7e-68 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
CHALKIFP_01216 2.4e-10
CHALKIFP_01217 2.7e-236 mntH P H( )-stimulated, divalent metal cation uptake system
CHALKIFP_01218 1.1e-33 XK27_12190 S protein conserved in bacteria
CHALKIFP_01220 5.8e-89 bioY S biotin synthase
CHALKIFP_01221 3.4e-252 yegQ O Peptidase U32
CHALKIFP_01222 3e-178 yegQ O Peptidase U32
CHALKIFP_01224 1e-67 ytxH S General stress protein
CHALKIFP_01226 1.5e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CHALKIFP_01227 3.1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CHALKIFP_01228 2.9e-41 pspC KT PspC domain
CHALKIFP_01229 4.9e-86 ydcK S Belongs to the SprT family
CHALKIFP_01230 0.0 yhgF K Transcriptional accessory protein
CHALKIFP_01232 4.4e-158 XK27_03015 S permease
CHALKIFP_01233 3.4e-149 ycgQ S TIGR03943 family
CHALKIFP_01234 7.4e-189 S CRISPR-associated protein Csn2 subfamily St
CHALKIFP_01235 2.4e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CHALKIFP_01236 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CHALKIFP_01237 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CHALKIFP_01238 4e-94
CHALKIFP_01239 2.4e-28 estA E GDSL-like Lipase/Acylhydrolase
CHALKIFP_01240 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
CHALKIFP_01241 1e-31 K Cro/C1-type HTH DNA-binding domain
CHALKIFP_01242 1.6e-84
CHALKIFP_01243 5.9e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHALKIFP_01244 7.7e-97 mip S hydroperoxide reductase activity
CHALKIFP_01245 4.8e-204 I acyl-CoA dehydrogenase
CHALKIFP_01246 2.9e-160 ydiA P C4-dicarboxylate transporter malic acid transport
CHALKIFP_01247 7.7e-177 msrR K Transcriptional regulator
CHALKIFP_01248 1.1e-59 msrR K Transcriptional regulator
CHALKIFP_01249 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
CHALKIFP_01250 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CHALKIFP_01251 1.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CHALKIFP_01252 1.1e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CHALKIFP_01253 3.2e-53 yheA S Belongs to the UPF0342 family
CHALKIFP_01254 1.1e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CHALKIFP_01255 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CHALKIFP_01256 4.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CHALKIFP_01257 3.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CHALKIFP_01258 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CHALKIFP_01259 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
CHALKIFP_01260 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CHALKIFP_01261 1.3e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CHALKIFP_01262 1.3e-78 yueI S Protein of unknown function (DUF1694)
CHALKIFP_01263 1.1e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CHALKIFP_01264 6.2e-145 yyaQ S YjbR
CHALKIFP_01265 4e-27 yyaQ S YjbR
CHALKIFP_01266 4.4e-183 ccpA K Catabolite control protein A
CHALKIFP_01267 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
CHALKIFP_01268 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
CHALKIFP_01269 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHALKIFP_01270 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CHALKIFP_01271 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CHALKIFP_01272 2e-33 secG U Preprotein translocase subunit SecG
CHALKIFP_01273 2.9e-221 mdtG EGP Major facilitator Superfamily
CHALKIFP_01274 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CHALKIFP_01275 5.5e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CHALKIFP_01276 2.2e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CHALKIFP_01277 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CHALKIFP_01278 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CHALKIFP_01279 3.4e-52 licT K transcriptional antiterminator
CHALKIFP_01280 5.8e-64 licT K transcriptional antiterminator
CHALKIFP_01281 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CHALKIFP_01282 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
CHALKIFP_01283 2.7e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CHALKIFP_01284 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CHALKIFP_01285 7.5e-23 I Alpha/beta hydrolase family
CHALKIFP_01286 5.9e-35 yugF I carboxylic ester hydrolase activity
CHALKIFP_01287 6.6e-08
CHALKIFP_01288 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
CHALKIFP_01289 4.1e-78 feoA P FeoA domain protein
CHALKIFP_01290 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
CHALKIFP_01291 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
CHALKIFP_01292 1.3e-34 ykuJ S protein conserved in bacteria
CHALKIFP_01293 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CHALKIFP_01294 0.0 clpE O Belongs to the ClpA ClpB family
CHALKIFP_01295 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CHALKIFP_01296 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
CHALKIFP_01297 1.4e-50 yvaA 1.1.1.371 S inositol 2-dehydrogenase activity
CHALKIFP_01298 7e-26 2.7.7.15 S inositol 2-dehydrogenase activity
CHALKIFP_01299 7.8e-08 S oxidoreductase
CHALKIFP_01300 5.8e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
CHALKIFP_01301 4.4e-68 M Pfam SNARE associated Golgi protein
CHALKIFP_01302 3.9e-31 S Domain of Unknown Function with PDB structure (DUF3862)
CHALKIFP_01303 5.1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
CHALKIFP_01306 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
CHALKIFP_01309 4.8e-16 S Protein of unknown function (DUF2969)
CHALKIFP_01310 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
CHALKIFP_01311 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CHALKIFP_01312 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CHALKIFP_01313 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CHALKIFP_01314 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
CHALKIFP_01315 1.4e-29 S Domain of unknown function (DUF1912)
CHALKIFP_01316 3.4e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
CHALKIFP_01317 1.1e-248 mmuP E amino acid
CHALKIFP_01318 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
CHALKIFP_01319 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CHALKIFP_01320 9.7e-22
CHALKIFP_01321 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CHALKIFP_01322 2.9e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CHALKIFP_01323 1.7e-218 mvaS 2.3.3.10 I synthase
CHALKIFP_01324 1.6e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CHALKIFP_01325 3.6e-120 yqfA K protein, Hemolysin III
CHALKIFP_01326 2.8e-13 S Protein of unknown function (DUF3114)
CHALKIFP_01327 7.3e-166 S Protein of unknown function (DUF3114)
CHALKIFP_01328 1.1e-170 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CHALKIFP_01329 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CHALKIFP_01330 6.4e-21 XK27_13030
CHALKIFP_01331 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
CHALKIFP_01332 1.5e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
CHALKIFP_01333 5.5e-51 U protein secretion
CHALKIFP_01334 3.5e-07 U protein secretion
CHALKIFP_01336 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CHALKIFP_01337 2.5e-21
CHALKIFP_01338 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
CHALKIFP_01339 5.6e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CHALKIFP_01340 5.2e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CHALKIFP_01341 4.3e-178 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
CHALKIFP_01342 2.5e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CHALKIFP_01343 9.6e-150 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
CHALKIFP_01344 4.6e-105 GBS0088 J protein conserved in bacteria
CHALKIFP_01345 1e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHALKIFP_01347 2e-43 ald 1.4.1.1 C Belongs to the AlaDH PNT family
CHALKIFP_01348 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
CHALKIFP_01349 6.8e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CHALKIFP_01350 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CHALKIFP_01351 2.5e-113 S VIT family
CHALKIFP_01352 2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
CHALKIFP_01353 4.3e-22
CHALKIFP_01354 1.9e-29 XK27_00085 K Transcriptional
CHALKIFP_01355 6.9e-197 yceA S Belongs to the UPF0176 family
CHALKIFP_01356 5.4e-122 sagI S ABC-2 type transporter
CHALKIFP_01357 4.8e-168 V ABC transporter
CHALKIFP_01358 1.9e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CHALKIFP_01359 1.9e-132 rr02 KT response regulator
CHALKIFP_01360 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
CHALKIFP_01361 2.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CHALKIFP_01362 1.8e-195 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CHALKIFP_01363 0.0 lmrA V abc transporter atp-binding protein
CHALKIFP_01364 0.0 mdlB V abc transporter atp-binding protein
CHALKIFP_01366 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CHALKIFP_01367 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CHALKIFP_01368 7e-27 ytrF V efflux transmembrane transporter activity
CHALKIFP_01369 3.7e-22 V efflux transmembrane transporter activity
CHALKIFP_01370 8.3e-35 V permease protein
CHALKIFP_01371 3.8e-43 V permease protein
CHALKIFP_01372 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHALKIFP_01373 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CHALKIFP_01374 1.7e-134 J Putative SAM-dependent methyltransferase
CHALKIFP_01375 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
CHALKIFP_01376 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
CHALKIFP_01377 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CHALKIFP_01378 3.7e-227 pyrP F uracil Permease
CHALKIFP_01379 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CHALKIFP_01380 1.3e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CHALKIFP_01381 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CHALKIFP_01382 3.4e-166 fhuR K transcriptional regulator (lysR family)
CHALKIFP_01387 6e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CHALKIFP_01388 2e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
CHALKIFP_01389 9e-96 pts33BCA G pts system
CHALKIFP_01390 5.8e-71 pts33BCA G pts system
CHALKIFP_01391 1.5e-25 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CHALKIFP_01392 1.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
CHALKIFP_01393 2.5e-253 cycA E permease
CHALKIFP_01394 4.5e-39 ynzC S UPF0291 protein
CHALKIFP_01395 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CHALKIFP_01396 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CHALKIFP_01397 7.8e-61
CHALKIFP_01398 2.8e-25
CHALKIFP_01399 7.4e-55
CHALKIFP_01400 2.3e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CHALKIFP_01401 3.2e-85 nptA P COG1283 Na phosphate symporter
CHALKIFP_01402 1.3e-32 nptA P sodium-dependent phosphate transmembrane transporter activity
CHALKIFP_01403 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
CHALKIFP_01404 3.2e-105 mur1 NU mannosyl-glycoprotein
CHALKIFP_01405 6.6e-54 glnB K Belongs to the P(II) protein family
CHALKIFP_01406 1.7e-232 amt P Ammonium Transporter
CHALKIFP_01407 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CHALKIFP_01408 9.5e-55 yabA L Involved in initiation control of chromosome replication
CHALKIFP_01409 1.2e-135 yaaT S stage 0 sporulation protein
CHALKIFP_01410 6.4e-162 holB 2.7.7.7 L dna polymerase iii
CHALKIFP_01411 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CHALKIFP_01412 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CHALKIFP_01413 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CHALKIFP_01414 8.1e-230 ftsW D Belongs to the SEDS family
CHALKIFP_01415 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CHALKIFP_01416 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CHALKIFP_01417 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CHALKIFP_01418 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CHALKIFP_01419 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHALKIFP_01420 3.3e-78 atpF C ATP synthase F(0) sector subunit b
CHALKIFP_01421 2.4e-114 atpB C it plays a direct role in the translocation of protons across the membrane
CHALKIFP_01422 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CHALKIFP_01423 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CHALKIFP_01424 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHALKIFP_01425 1.7e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CHALKIFP_01426 8.9e-14 coiA 3.6.4.12 S Competence protein
CHALKIFP_01427 2.2e-15 T peptidase
CHALKIFP_01428 7.2e-153 rarD S Transporter
CHALKIFP_01429 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CHALKIFP_01430 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CHALKIFP_01431 3.6e-140 yxkH G deacetylase
CHALKIFP_01432 1.1e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CHALKIFP_01433 1.8e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CHALKIFP_01434 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CHALKIFP_01435 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CHALKIFP_01436 2.4e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
CHALKIFP_01437 5.3e-147 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CHALKIFP_01438 1.2e-53 3.4.17.14, 3.5.1.28 NU amidase activity
CHALKIFP_01439 4.2e-59 3.4.17.14, 3.5.1.28 NU amidase activity
CHALKIFP_01440 5.8e-42 S pathogenesis
CHALKIFP_01441 1.7e-92 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CHALKIFP_01442 4.6e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CHALKIFP_01443 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CHALKIFP_01444 1.2e-176 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
CHALKIFP_01445 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
CHALKIFP_01446 0.0 pepF E oligoendopeptidase F
CHALKIFP_01447 1.4e-186 coiA 3.6.4.12 S Competence protein
CHALKIFP_01448 3.4e-166 K transcriptional regulator (lysR family)
CHALKIFP_01449 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CHALKIFP_01453 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
CHALKIFP_01454 1.4e-61 rlpA M LysM domain protein
CHALKIFP_01455 9e-184 L Transposase
CHALKIFP_01456 2.8e-122 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
CHALKIFP_01457 7.4e-35 yozE S Belongs to the UPF0346 family
CHALKIFP_01458 5.3e-161 cvfB S Protein conserved in bacteria
CHALKIFP_01459 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CHALKIFP_01460 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CHALKIFP_01461 2.3e-122 sptS 2.7.13.3 T Histidine kinase
CHALKIFP_01462 0.0 lmrA2 V abc transporter atp-binding protein
CHALKIFP_01463 0.0 lmrA1 V abc transporter atp-binding protein
CHALKIFP_01464 3.6e-38 K DNA-binding transcription factor activity
CHALKIFP_01465 1.4e-27 K DNA-binding transcription factor activity
CHALKIFP_01467 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CHALKIFP_01468 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
CHALKIFP_01469 2.2e-215 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
CHALKIFP_01470 1.4e-136 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
CHALKIFP_01471 1.6e-24 U response to pH
CHALKIFP_01472 0.0 yfmR S abc transporter atp-binding protein
CHALKIFP_01473 1.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CHALKIFP_01474 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CHALKIFP_01475 3.4e-109 XK27_08360 T EDD domain protein, DegV family
CHALKIFP_01476 2.9e-31 XK27_08360 S lipid binding
CHALKIFP_01477 2.6e-64 WQ51_03320 S cog cog4835
CHALKIFP_01478 1.3e-37 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHALKIFP_01479 2.1e-99 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CHALKIFP_01480 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CHALKIFP_01481 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CHALKIFP_01482 6.4e-29 2.3.1.128 K acetyltransferase
CHALKIFP_01483 1.1e-38 2.3.1.128 K acetyltransferase
CHALKIFP_01484 8e-257 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CHALKIFP_01485 8.4e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CHALKIFP_01486 7.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CHALKIFP_01487 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
CHALKIFP_01489 5.3e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CHALKIFP_01490 1.6e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CHALKIFP_01491 1.5e-47 fruA 2.7.1.202 G phosphotransferase system
CHALKIFP_01492 2.2e-104 fruA 2.7.1.202 G phosphotransferase system
CHALKIFP_01493 1.4e-25 fruA 2.7.1.202 G phosphotransferase system
CHALKIFP_01494 1.7e-21 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
CHALKIFP_01495 7.3e-12 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
CHALKIFP_01496 9.6e-53 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
CHALKIFP_01497 6.5e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CHALKIFP_01498 5.6e-114 fruR K transcriptional
CHALKIFP_01499 4.7e-85 L Transposase
CHALKIFP_01500 9.2e-207 rny D Endoribonuclease that initiates mRNA decay
CHALKIFP_01501 1.8e-127 tnp L Transposase
CHALKIFP_01502 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CHALKIFP_01503 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CHALKIFP_01504 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CHALKIFP_01505 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CHALKIFP_01506 2.1e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CHALKIFP_01507 1.1e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CHALKIFP_01508 9.8e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CHALKIFP_01509 1.3e-126 IQ reductase
CHALKIFP_01510 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CHALKIFP_01511 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
CHALKIFP_01512 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CHALKIFP_01513 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CHALKIFP_01514 5.8e-52 marR K Transcriptional regulator, MarR family
CHALKIFP_01515 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
CHALKIFP_01516 4.3e-115 S Haloacid dehalogenase-like hydrolase
CHALKIFP_01517 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
CHALKIFP_01518 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
CHALKIFP_01519 5.2e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CHALKIFP_01520 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
CHALKIFP_01521 7.8e-102 ygaC J Belongs to the UPF0374 family
CHALKIFP_01522 6.4e-108 S Domain of unknown function (DUF1803)
CHALKIFP_01523 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
CHALKIFP_01531 9.4e-183 L Transposase and inactivated derivatives IS30 family
CHALKIFP_01532 9.4e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CHALKIFP_01533 3.4e-123 comFC S Competence protein
CHALKIFP_01534 8.2e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CHALKIFP_01535 1.4e-110 yvyE 3.4.13.9 S YigZ family
CHALKIFP_01536 2.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CHALKIFP_01537 5.6e-43 acuB S IMP dehydrogenase activity
CHALKIFP_01538 9.5e-71 acuB S IMP dehydrogenase activity
CHALKIFP_01539 2.1e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
CHALKIFP_01540 8.2e-137 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
CHALKIFP_01541 7.7e-137 livM E Belongs to the binding-protein-dependent transport system permease family
CHALKIFP_01542 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
CHALKIFP_01543 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
CHALKIFP_01544 7.1e-46 ylbG S UPF0298 protein
CHALKIFP_01545 1.2e-74 ylbF S Belongs to the UPF0342 family
CHALKIFP_01546 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CHALKIFP_01547 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CHALKIFP_01549 6.5e-176 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CHALKIFP_01550 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
CHALKIFP_01551 1e-87 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
CHALKIFP_01552 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
CHALKIFP_01553 3.8e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CHALKIFP_01554 1.4e-234 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
CHALKIFP_01555 4e-38 yvdD 3.2.2.10 L Belongs to the LOG family
CHALKIFP_01556 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
CHALKIFP_01557 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CHALKIFP_01558 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CHALKIFP_01559 1.4e-41 ylxQ J ribosomal protein
CHALKIFP_01560 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
CHALKIFP_01561 4.1e-212 nusA K Participates in both transcription termination and antitermination
CHALKIFP_01562 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
CHALKIFP_01563 2.5e-220 brpA K Transcriptional
CHALKIFP_01564 7.1e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
CHALKIFP_01565 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
CHALKIFP_01566 1.5e-248 pbuO S permease
CHALKIFP_01567 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
CHALKIFP_01568 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
CHALKIFP_01569 9.8e-183 manL 2.7.1.191 G pts system
CHALKIFP_01570 2.7e-117 manM G pts system
CHALKIFP_01571 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
CHALKIFP_01572 5e-63 manO S protein conserved in bacteria
CHALKIFP_01573 4.6e-233 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CHALKIFP_01574 9.8e-25 S Protein of unknown function DUF262
CHALKIFP_01575 1.1e-147 L Transposase
CHALKIFP_01576 7.5e-50 L Transposase
CHALKIFP_01578 3.5e-283 P ABC transporter transmembrane region
CHALKIFP_01579 1.1e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CHALKIFP_01580 4e-167 dnaI L Primosomal protein DnaI
CHALKIFP_01581 3.8e-218 dnaB L Replication initiation and membrane attachment
CHALKIFP_01582 1.8e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CHALKIFP_01583 3.7e-282 T PhoQ Sensor
CHALKIFP_01584 8.7e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CHALKIFP_01585 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
CHALKIFP_01586 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
CHALKIFP_01587 4.2e-245 P COG0168 Trk-type K transport systems, membrane components
CHALKIFP_01588 3.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
CHALKIFP_01589 1.8e-11 ulaG S L-ascorbate 6-phosphate lactonase
CHALKIFP_01590 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CHALKIFP_01591 1.7e-148 cbiQ P cobalt transport
CHALKIFP_01592 0.0 ykoD P abc transporter atp-binding protein
CHALKIFP_01593 8e-94 S UPF0397 protein
CHALKIFP_01594 3.2e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
CHALKIFP_01595 1e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CHALKIFP_01596 1.2e-97 metI P ABC transporter (Permease
CHALKIFP_01597 1.5e-178 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CHALKIFP_01598 1.4e-17 ET amino acid transport
CHALKIFP_01599 3.8e-205 EGP Transmembrane secretion effector
CHALKIFP_01600 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
CHALKIFP_01601 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CHALKIFP_01602 3.4e-152 ET amino acid transport
CHALKIFP_01603 1.6e-131 cbiO P ABC transporter
CHALKIFP_01604 2.9e-137 P cobalt transport protein
CHALKIFP_01605 3.5e-177 cbiM P PDGLE domain
CHALKIFP_01606 5.8e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CHALKIFP_01607 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CHALKIFP_01608 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CHALKIFP_01609 6.6e-78 ureE O enzyme active site formation
CHALKIFP_01610 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CHALKIFP_01611 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CHALKIFP_01612 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CHALKIFP_01613 7.5e-94 ureI S AmiS/UreI family transporter
CHALKIFP_01614 1.6e-53 S Domain of unknown function (DUF4173)
CHALKIFP_01615 2.6e-35 S Domain of unknown function (DUF4173)
CHALKIFP_01616 1.6e-43 yhaI L Membrane
CHALKIFP_01617 1.4e-69 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CHALKIFP_01618 4.3e-63 comA V protein secretion by the type I secretion system
CHALKIFP_01619 6.9e-34 V protein secretion by the type I secretion system
CHALKIFP_01620 1.6e-109 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CHALKIFP_01621 1.9e-33 V protein secretion by the type I secretion system
CHALKIFP_01622 2.5e-161 K sequence-specific DNA binding
CHALKIFP_01623 7e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
CHALKIFP_01624 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CHALKIFP_01625 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CHALKIFP_01626 1.8e-248 trkA P Potassium transporter peripheral membrane component
CHALKIFP_01627 1.2e-258 trkH P Cation transport protein
CHALKIFP_01628 8.6e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
CHALKIFP_01629 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CHALKIFP_01630 2.3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CHALKIFP_01631 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CHALKIFP_01632 7.5e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
CHALKIFP_01633 5.4e-86 ykuL S CBS domain
CHALKIFP_01634 3.5e-99 XK27_09740 S Phosphoesterase
CHALKIFP_01635 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CHALKIFP_01636 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CHALKIFP_01637 7.6e-36 yneF S UPF0154 protein
CHALKIFP_01638 9.6e-92 K transcriptional regulator
CHALKIFP_01639 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CHALKIFP_01642 3.3e-97 ybhL S Belongs to the BI1 family
CHALKIFP_01643 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
CHALKIFP_01644 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CHALKIFP_01645 2.7e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CHALKIFP_01646 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CHALKIFP_01647 4.3e-83 L Integrase core domain protein
CHALKIFP_01648 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CHALKIFP_01649 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CHALKIFP_01650 4.6e-58 XK27_09675 K -acetyltransferase
CHALKIFP_01651 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CHALKIFP_01652 2.5e-23
CHALKIFP_01653 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
CHALKIFP_01654 6.7e-181 L Transposase and inactivated derivatives IS30 family
CHALKIFP_01655 0.0 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
CHALKIFP_01656 5.1e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CHALKIFP_01657 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CHALKIFP_01658 8.9e-95 ypsA S Belongs to the UPF0398 family
CHALKIFP_01659 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CHALKIFP_01660 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CHALKIFP_01661 6e-260 pepC 3.4.22.40 E aminopeptidase
CHALKIFP_01662 5.5e-77 yhaI L Membrane
CHALKIFP_01663 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CHALKIFP_01664 9.6e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CHALKIFP_01665 8.1e-145 S COG1073 Hydrolases of the alpha beta superfamily
CHALKIFP_01666 1.7e-93 S thiolester hydrolase activity
CHALKIFP_01667 9.7e-41 L Transposase and inactivated derivatives IS30 family
CHALKIFP_01668 1.8e-127 L Transposase and inactivated derivatives IS30 family
CHALKIFP_01669 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CHALKIFP_01670 1.1e-136 glcR K transcriptional regulator (DeoR family)
CHALKIFP_01671 3.3e-36 cof Q phosphatase activity
CHALKIFP_01672 7e-56 cof Q phosphatase activity
CHALKIFP_01673 6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
CHALKIFP_01674 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
CHALKIFP_01675 7.4e-25 secE U Belongs to the SecE SEC61-gamma family
CHALKIFP_01676 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CHALKIFP_01677 5.6e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CHALKIFP_01678 2.7e-28 J TM2 domain
CHALKIFP_01679 4e-42
CHALKIFP_01682 4.8e-34 L Integrase core domain protein
CHALKIFP_01683 1.7e-51 L transposition
CHALKIFP_01684 2.6e-77 L transposase activity
CHALKIFP_01685 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CHALKIFP_01686 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CHALKIFP_01687 2.6e-141 cmpC S abc transporter atp-binding protein
CHALKIFP_01688 0.0 WQ51_06230 S ABC transporter substrate binding protein
CHALKIFP_01689 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CHALKIFP_01690 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CHALKIFP_01691 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
CHALKIFP_01692 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CHALKIFP_01693 9.8e-50 yajC U protein transport
CHALKIFP_01694 1.9e-127 yeeN K transcriptional regulatory protein
CHALKIFP_01695 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
CHALKIFP_01696 2e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
CHALKIFP_01697 8.5e-108 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CHALKIFP_01698 1.4e-154 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
CHALKIFP_01699 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
CHALKIFP_01700 4.3e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
CHALKIFP_01701 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
CHALKIFP_01702 2.8e-127 adcB P ABC transporter (Permease
CHALKIFP_01703 6.4e-136 adcC P ABC transporter, ATP-binding protein
CHALKIFP_01704 3.1e-72 adcR K transcriptional
CHALKIFP_01705 1.9e-223 EGP Major facilitator Superfamily
CHALKIFP_01706 0.0 KLT serine threonine protein kinase
CHALKIFP_01707 6e-128 K sequence-specific DNA binding
CHALKIFP_01708 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CHALKIFP_01709 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CHALKIFP_01710 5.1e-11
CHALKIFP_01711 8.7e-165 oppF P Belongs to the ABC transporter superfamily
CHALKIFP_01712 1.3e-44 oppD P Belongs to the ABC transporter superfamily
CHALKIFP_01713 3.3e-68 oppD P Belongs to the ABC transporter superfamily
CHALKIFP_01714 2.5e-32 oppD P Belongs to the ABC transporter superfamily
CHALKIFP_01715 3e-27 oppD P Belongs to the ABC transporter superfamily
CHALKIFP_01716 2e-59 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHALKIFP_01717 2.7e-45 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHALKIFP_01718 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHALKIFP_01719 1.9e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
CHALKIFP_01720 9.7e-138 oppA E ABC transporter substrate-binding protein
CHALKIFP_01721 2.4e-19 oppA E ABC transporter substrate-binding protein
CHALKIFP_01722 2.2e-273 sufB O assembly protein SufB
CHALKIFP_01723 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
CHALKIFP_01724 1.5e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CHALKIFP_01725 1.4e-234 sufD O assembly protein SufD
CHALKIFP_01726 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CHALKIFP_01727 3.8e-186 tagO 2.7.8.33, 2.7.8.35 M transferase
CHALKIFP_01728 1.4e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CHALKIFP_01729 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CHALKIFP_01730 5.8e-275 glnP P ABC transporter
CHALKIFP_01731 1.7e-123 glnQ E abc transporter atp-binding protein
CHALKIFP_01734 5e-94 V VanZ like family
CHALKIFP_01735 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CHALKIFP_01736 9.3e-201 yhjX P Major Facilitator
CHALKIFP_01737 1.2e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
CHALKIFP_01738 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CHALKIFP_01739 2.3e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CHALKIFP_01740 2.5e-48 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CHALKIFP_01741 1.6e-64 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CHALKIFP_01742 5.7e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CHALKIFP_01743 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CHALKIFP_01744 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CHALKIFP_01745 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CHALKIFP_01746 1.8e-83 nrdI F Belongs to the NrdI family
CHALKIFP_01747 2.9e-183 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CHALKIFP_01748 9.1e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CHALKIFP_01749 1.2e-29 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CHALKIFP_01750 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CHALKIFP_01751 9.1e-178 prmA J Ribosomal protein L11 methyltransferase
CHALKIFP_01752 1e-56 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
CHALKIFP_01753 4.2e-83 XK27_03960 S Protein of unknown function (DUF3013)
CHALKIFP_01754 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CHALKIFP_01755 6.3e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CHALKIFP_01756 4.9e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CHALKIFP_01757 9.3e-150 ykuT M mechanosensitive ion channel
CHALKIFP_01758 1.6e-77 sigH K DNA-templated transcription, initiation
CHALKIFP_01759 3.2e-86
CHALKIFP_01760 4.2e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CHALKIFP_01761 3.3e-55 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CHALKIFP_01762 9.9e-19 S Domain of unknown function (DUF4649)
CHALKIFP_01763 2.5e-169 L Transposase
CHALKIFP_01764 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CHALKIFP_01767 4.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CHALKIFP_01768 1.6e-87 L Transposase
CHALKIFP_01769 1e-13 rpmH J Ribosomal protein L34
CHALKIFP_01770 1.2e-83 jag S RNA-binding protein
CHALKIFP_01771 3.9e-63 jag S RNA-binding protein
CHALKIFP_01772 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CHALKIFP_01773 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CHALKIFP_01774 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
CHALKIFP_01775 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CHALKIFP_01776 4.6e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CHALKIFP_01777 1.4e-81 amiA E transmembrane transport
CHALKIFP_01778 4.9e-75 amiA E transmembrane transport
CHALKIFP_01779 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CHALKIFP_01780 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CHALKIFP_01781 9.2e-51 S Protein of unknown function (DUF3397)
CHALKIFP_01782 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
CHALKIFP_01783 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
CHALKIFP_01784 8.1e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
CHALKIFP_01785 4.8e-227 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CHALKIFP_01786 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
CHALKIFP_01787 7.9e-64 XK27_09620 S FMN reductase (NADPH) activity
CHALKIFP_01788 8.3e-34 XK27_09620 S FMN reductase (NADPH) activity
CHALKIFP_01789 6.6e-34 XK27_09615 S FMN reductase (NADPH) activity
CHALKIFP_01790 1.9e-132 XK27_09615 S PAS domain
CHALKIFP_01791 3.8e-08 fnt P Formate nitrite transporter
CHALKIFP_01792 2.9e-63 fnt P Formate nitrite transporter
CHALKIFP_01793 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
CHALKIFP_01794 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CHALKIFP_01795 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CHALKIFP_01796 2e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
CHALKIFP_01797 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CHALKIFP_01798 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CHALKIFP_01799 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CHALKIFP_01800 2.7e-48 S glycolate biosynthetic process
CHALKIFP_01801 4e-65 S phosphatase activity
CHALKIFP_01802 2.4e-158 rrmA 2.1.1.187 Q methyltransferase
CHALKIFP_01804 4.6e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CHALKIFP_01805 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CHALKIFP_01806 8.3e-37 yeeD O sulfur carrier activity
CHALKIFP_01807 1.9e-189 yeeE S Sulphur transport
CHALKIFP_01808 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CHALKIFP_01809 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CHALKIFP_01810 7e-09 S Domain of unknown function (DUF4651)
CHALKIFP_01811 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
CHALKIFP_01812 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CHALKIFP_01813 1.9e-110 S CAAX amino terminal protease family protein
CHALKIFP_01815 7.6e-68 V CAAX protease self-immunity
CHALKIFP_01816 8.8e-27 lanR K sequence-specific DNA binding
CHALKIFP_01817 2.6e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CHALKIFP_01818 5.9e-177 ytxK 2.1.1.72 L DNA methylase
CHALKIFP_01819 6.8e-13 comGF U Putative Competence protein ComGF
CHALKIFP_01820 3.4e-71 comGF U Competence protein ComGF
CHALKIFP_01821 1.4e-15 NU Type II secretory pathway pseudopilin
CHALKIFP_01822 1.8e-57 cglD NU Competence protein
CHALKIFP_01823 8.5e-43 comGC U Required for transformation and DNA binding
CHALKIFP_01824 9.2e-153 cglB NU type II secretion system
CHALKIFP_01825 4.5e-177 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CHALKIFP_01826 1e-68 S cog cog4699
CHALKIFP_01827 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHALKIFP_01828 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHALKIFP_01829 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CHALKIFP_01830 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CHALKIFP_01831 1.2e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CHALKIFP_01832 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
CHALKIFP_01833 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
CHALKIFP_01834 3.3e-283 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CHALKIFP_01835 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CHALKIFP_01836 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
CHALKIFP_01837 1.4e-57 asp S cog cog1302
CHALKIFP_01838 8.4e-227 norM V Mate efflux family protein
CHALKIFP_01839 1.9e-278 thrC 4.2.3.1 E Threonine synthase
CHALKIFP_01840 1.4e-62 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CHALKIFP_01841 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
CHALKIFP_01842 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CHALKIFP_01843 7.4e-103 1.1.1.1, 1.1.99.1, 1.2.1.10, 1.2.1.18, 1.2.1.27, 1.2.1.3 C Dehydrogenase
CHALKIFP_01844 5.1e-66 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
CHALKIFP_01845 0.0 pepO 3.4.24.71 O Peptidase family M13
CHALKIFP_01846 2.3e-120 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CHALKIFP_01847 7e-67 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CHALKIFP_01848 2e-56 treB 2.7.1.201 G PTS System
CHALKIFP_01849 5.8e-21 treR K DNA-binding transcription factor activity
CHALKIFP_01850 2.3e-87 treR K trehalose operon
CHALKIFP_01851 5.7e-95 ywlG S Belongs to the UPF0340 family
CHALKIFP_01854 2.7e-13 L PFAM Integrase, catalytic core
CHALKIFP_01855 4e-75 L PFAM Integrase, catalytic core
CHALKIFP_01856 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
CHALKIFP_01858 3.9e-110 6.3.2.2 H ergothioneine biosynthetic process
CHALKIFP_01859 1.1e-16 6.3.2.2 H gamma-glutamylcysteine synthetase
CHALKIFP_01860 2.5e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
CHALKIFP_01861 1.2e-32 L PFAM Integrase, catalytic core
CHALKIFP_01862 1.4e-70 L PFAM Integrase, catalytic core
CHALKIFP_01863 3.3e-62 rplQ J ribosomal protein l17
CHALKIFP_01864 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CHALKIFP_01865 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CHALKIFP_01866 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CHALKIFP_01867 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CHALKIFP_01868 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CHALKIFP_01869 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CHALKIFP_01870 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CHALKIFP_01871 7.4e-58 rplO J binds to the 23S rRNA
CHALKIFP_01872 2.5e-23 rpmD J ribosomal protein l30
CHALKIFP_01873 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CHALKIFP_01874 1.1e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CHALKIFP_01875 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CHALKIFP_01876 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CHALKIFP_01877 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CHALKIFP_01878 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CHALKIFP_01879 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CHALKIFP_01880 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CHALKIFP_01881 2e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CHALKIFP_01882 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
CHALKIFP_01883 3.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CHALKIFP_01884 3.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CHALKIFP_01885 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CHALKIFP_01886 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CHALKIFP_01887 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CHALKIFP_01888 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CHALKIFP_01889 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
CHALKIFP_01890 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CHALKIFP_01891 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
CHALKIFP_01892 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CHALKIFP_01893 0.0 XK27_09800 I Acyltransferase
CHALKIFP_01894 1.7e-35 XK27_09805 S MORN repeat protein
CHALKIFP_01895 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CHALKIFP_01896 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CHALKIFP_01897 8.9e-95 adk 2.7.4.3 F topology modulation protein
CHALKIFP_01898 3.1e-172 yxaM EGP Major facilitator Superfamily
CHALKIFP_01899 2.5e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
CHALKIFP_01900 6.3e-54 L Transposase
CHALKIFP_01901 4.1e-147 L Transposase
CHALKIFP_01903 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CHALKIFP_01904 0.0 KLT serine threonine protein kinase
CHALKIFP_01905 3.1e-67 V ABC transporter
CHALKIFP_01906 1.2e-197 V ABC transporter
CHALKIFP_01907 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CHALKIFP_01908 3.7e-128 Z012_04635 K sequence-specific DNA binding
CHALKIFP_01910 3.6e-232 C Radical SAM
CHALKIFP_01911 3.9e-287 V ABC transporter transmembrane region
CHALKIFP_01912 2.9e-155 L Replication initiation factor
CHALKIFP_01913 1.9e-18 S Domain of unknown function (DUF3173)
CHALKIFP_01914 3.5e-216 int L Belongs to the 'phage' integrase family
CHALKIFP_01916 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
CHALKIFP_01917 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CHALKIFP_01918 2.2e-44 yrzL S Belongs to the UPF0297 family
CHALKIFP_01919 9.5e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CHALKIFP_01920 4.2e-44 yrzB S Belongs to the UPF0473 family
CHALKIFP_01921 3.5e-302 ccs S the current gene model (or a revised gene model) may contain a frame shift
CHALKIFP_01922 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CHALKIFP_01923 7.5e-14
CHALKIFP_01924 3.4e-91 XK27_10930 K acetyltransferase
CHALKIFP_01925 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CHALKIFP_01926 1.3e-145 yaaA S Belongs to the UPF0246 family
CHALKIFP_01927 3.4e-169 XK27_01785 S cog cog1284
CHALKIFP_01928 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CHALKIFP_01930 1.2e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
CHALKIFP_01931 4.3e-130 metE 2.1.1.14 E Methionine synthase
CHALKIFP_01932 1.4e-36 metE 2.1.1.14 E Methionine synthase
CHALKIFP_01933 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CHALKIFP_01934 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CHALKIFP_01937 4.8e-51 yegS 2.7.1.107 I lipid kinase activity
CHALKIFP_01938 8.5e-97 S Hydrophobic domain protein
CHALKIFP_01940 7.4e-28 S Membrane
CHALKIFP_01941 1.4e-101
CHALKIFP_01942 1.8e-23 S Small integral membrane protein
CHALKIFP_01943 1.5e-78 M Protein conserved in bacteria
CHALKIFP_01944 2.8e-12 K CsbD-like
CHALKIFP_01945 1.8e-101 nudL L hydrolase
CHALKIFP_01946 3.4e-13 nudL L hydrolase
CHALKIFP_01947 3e-48 K transcriptional regulator, PadR family
CHALKIFP_01949 8e-109 S Putative adhesin
CHALKIFP_01950 5.6e-160 XK27_06930 V domain protein
CHALKIFP_01951 6.4e-96 XK27_06935 K transcriptional regulator
CHALKIFP_01952 4.8e-55 ypaA S membrane
CHALKIFP_01953 2.7e-08
CHALKIFP_01954 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CHALKIFP_01955 4e-47 veg S Biofilm formation stimulator VEG
CHALKIFP_01956 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CHALKIFP_01957 6.7e-70 rplI J binds to the 23S rRNA
CHALKIFP_01958 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CHALKIFP_01959 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CHALKIFP_01960 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CHALKIFP_01961 0.0 S Bacterial membrane protein, YfhO
CHALKIFP_01962 4.6e-93 isaA GH23 M Immunodominant staphylococcal antigen A
CHALKIFP_01963 3.1e-93 lytE M LysM domain protein
CHALKIFP_01964 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CHALKIFP_01965 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CHALKIFP_01966 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CHALKIFP_01967 1.2e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CHALKIFP_01968 1.7e-138 ymfM S sequence-specific DNA binding
CHALKIFP_01969 1.2e-241 ymfH S Peptidase M16
CHALKIFP_01970 4.8e-235 ymfF S Peptidase M16
CHALKIFP_01971 1.6e-45 yaaA S S4 domain protein YaaA
CHALKIFP_01972 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CHALKIFP_01973 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CHALKIFP_01974 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CHALKIFP_01975 4.2e-153 yvjA S membrane
CHALKIFP_01976 6.7e-306 ybiT S abc transporter atp-binding protein
CHALKIFP_01977 0.0 XK27_10405 S Bacterial membrane protein YfhO
CHALKIFP_01981 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
CHALKIFP_01982 8.6e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CHALKIFP_01983 1.1e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
CHALKIFP_01984 7.7e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)