ORF_ID e_value Gene_name EC_number CAZy COGs Description
HFCLIPBE_00001 2.5e-146 cobB2 K Sir2 family
HFCLIPBE_00002 3.3e-231 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HFCLIPBE_00003 1.7e-22 K Bacterial regulatory proteins, tetR family
HFCLIPBE_00004 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HFCLIPBE_00005 0.0 rafA 3.2.1.22 G Raffinose synthase or seed imbibition protein Sip1
HFCLIPBE_00006 2.2e-243 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HFCLIPBE_00007 3e-71 K Periplasmic binding protein-like domain
HFCLIPBE_00008 2.1e-146 G Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00009 1.1e-167 G Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00010 4.9e-243 msmE7 G Bacterial extracellular solute-binding protein
HFCLIPBE_00011 1.7e-232 nagC GK ROK family
HFCLIPBE_00012 1.5e-65 S Domain of unknown function (DUF5067)
HFCLIPBE_00013 2.6e-176 T Histidine kinase
HFCLIPBE_00014 7.6e-113 K helix_turn_helix, Lux Regulon
HFCLIPBE_00015 7.9e-141 S membrane transporter protein
HFCLIPBE_00016 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HFCLIPBE_00017 1.6e-73 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFCLIPBE_00018 0.0 yjcE P Sodium/hydrogen exchanger family
HFCLIPBE_00019 1.8e-134 ypfH S Phospholipase/Carboxylesterase
HFCLIPBE_00020 4.5e-90
HFCLIPBE_00021 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HFCLIPBE_00022 1.1e-170 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFCLIPBE_00023 1.3e-263 KLT Domain of unknown function (DUF4032)
HFCLIPBE_00024 6.9e-209 ugpC E Belongs to the ABC transporter superfamily
HFCLIPBE_00025 4.1e-93 K LytTr DNA-binding domain
HFCLIPBE_00026 3.5e-167 T GHKL domain
HFCLIPBE_00027 3e-73 S GtrA-like protein
HFCLIPBE_00028 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HFCLIPBE_00029 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
HFCLIPBE_00030 6.8e-224 KLT Protein tyrosine kinase
HFCLIPBE_00031 1.8e-88 O Thioredoxin
HFCLIPBE_00033 2.3e-178 S G5
HFCLIPBE_00034 6.6e-128 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFCLIPBE_00035 8.7e-109 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFCLIPBE_00036 2.9e-92 S LytR cell envelope-related transcriptional attenuator
HFCLIPBE_00037 6.6e-244 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HFCLIPBE_00038 1.4e-113 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HFCLIPBE_00039 4e-227
HFCLIPBE_00040 0.0 murJ KLT MviN-like protein
HFCLIPBE_00041 5.2e-141 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFCLIPBE_00043 3.7e-128 parB K Belongs to the ParB family
HFCLIPBE_00044 1.8e-154 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HFCLIPBE_00045 3.9e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HFCLIPBE_00046 2.7e-84 jag S Putative single-stranded nucleic acids-binding domain
HFCLIPBE_00047 7.6e-167 yidC U Membrane protein insertase, YidC Oxa1 family
HFCLIPBE_00048 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HFCLIPBE_00049 2.7e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFCLIPBE_00050 5.3e-193 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFCLIPBE_00051 6.4e-162 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFCLIPBE_00052 1.9e-67 S Protein of unknown function (DUF721)
HFCLIPBE_00053 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFCLIPBE_00054 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFCLIPBE_00055 7.5e-62 S Transmembrane domain of unknown function (DUF3566)
HFCLIPBE_00056 2.5e-163 I Serine aminopeptidase, S33
HFCLIPBE_00057 3.1e-183 V VanZ like family
HFCLIPBE_00058 2e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HFCLIPBE_00059 3.2e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFCLIPBE_00062 4.5e-126 S SOS response associated peptidase (SRAP)
HFCLIPBE_00063 1.6e-129 S Protein of unknown function DUF45
HFCLIPBE_00064 3e-238 ytfL P Transporter associated domain
HFCLIPBE_00065 2.1e-100 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HFCLIPBE_00066 1.1e-106 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HFCLIPBE_00067 5.4e-301 trxB1 1.8.1.9 C Thioredoxin domain
HFCLIPBE_00068 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HFCLIPBE_00069 2.2e-278 yjjP S Threonine/Serine exporter, ThrE
HFCLIPBE_00070 2e-111 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HFCLIPBE_00071 7.3e-225 malY 4.4.1.8 E Aminotransferase, class I II
HFCLIPBE_00072 4.6e-22
HFCLIPBE_00073 1.8e-195 pldB 3.1.1.5 I Serine aminopeptidase, S33
HFCLIPBE_00074 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HFCLIPBE_00076 4.5e-126 fhaA T Protein of unknown function (DUF2662)
HFCLIPBE_00077 4.7e-59 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HFCLIPBE_00078 8.4e-243 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HFCLIPBE_00079 1.4e-232 rodA D Belongs to the SEDS family
HFCLIPBE_00080 8.1e-242 pbpA M penicillin-binding protein
HFCLIPBE_00081 3.6e-180 T Protein tyrosine kinase
HFCLIPBE_00082 1.6e-304 pknB 2.7.11.1 KLT Protein tyrosine kinase
HFCLIPBE_00083 8.5e-111 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HFCLIPBE_00084 7.1e-170 srtA 3.4.22.70 M Sortase family
HFCLIPBE_00085 1.6e-92 S Bacterial protein of unknown function (DUF881)
HFCLIPBE_00086 1.8e-58 crgA D Involved in cell division
HFCLIPBE_00087 2.3e-165 L ribosomal rna small subunit methyltransferase
HFCLIPBE_00088 1.3e-110 gluP 3.4.21.105 S Rhomboid family
HFCLIPBE_00089 2.5e-27
HFCLIPBE_00090 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HFCLIPBE_00091 8.7e-72 I Sterol carrier protein
HFCLIPBE_00092 1.9e-200 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFCLIPBE_00093 6.8e-60 S Protein of unknown function (DUF3073)
HFCLIPBE_00094 4.5e-260 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFCLIPBE_00096 2.6e-191 ltaE 4.1.2.48 E Beta-eliminating lyase
HFCLIPBE_00098 2.9e-137 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HFCLIPBE_00099 5e-196 exeA S Peptidase_C39 like family
HFCLIPBE_00100 7.4e-281 P Oligopeptide/dipeptide transporter, C-terminal region
HFCLIPBE_00101 7.8e-146 EP Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00102 1.1e-165 U Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00103 2e-281 E Bacterial extracellular solute-binding proteins, family 5 Middle
HFCLIPBE_00104 1.6e-108 3.5.2.10 S Creatinine amidohydrolase
HFCLIPBE_00105 2.5e-197 proP EGP Sugar (and other) transporter
HFCLIPBE_00106 3.7e-291 purR QT Purine catabolism regulatory protein-like family
HFCLIPBE_00107 5.7e-255 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
HFCLIPBE_00108 6.2e-280 EK Alanine-glyoxylate amino-transferase
HFCLIPBE_00109 2.9e-248 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HFCLIPBE_00110 8.5e-242 M Glycosyltransferase like family 2
HFCLIPBE_00111 4.3e-112 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HFCLIPBE_00112 2.8e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HFCLIPBE_00114 1.5e-296 cysB 4.2.1.22 EGP Major facilitator Superfamily
HFCLIPBE_00115 0.0 cadA P E1-E2 ATPase
HFCLIPBE_00116 2.2e-65 gepA S Protein of unknown function (DUF4065)
HFCLIPBE_00117 7.1e-147 2.7.6.5 S Region found in RelA / SpoT proteins
HFCLIPBE_00118 3.6e-282 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HFCLIPBE_00119 3.7e-174 htpX O Belongs to the peptidase M48B family
HFCLIPBE_00120 9.4e-49 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
HFCLIPBE_00121 2.8e-67 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFCLIPBE_00122 1.3e-168 yddG EG EamA-like transporter family
HFCLIPBE_00124 3.1e-35 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
HFCLIPBE_00125 2.7e-31 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HFCLIPBE_00127 3.8e-12 rpmJ J Ribosomal protein L36
HFCLIPBE_00128 6.7e-27 rpmE2 J Ribosomal protein L31
HFCLIPBE_00129 2.9e-37 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFCLIPBE_00130 7.5e-19 rpmG J Ribosomal protein L33
HFCLIPBE_00131 2.5e-26 rpmB J Ribosomal L28 family
HFCLIPBE_00132 3.5e-51 S cobalamin synthesis protein
HFCLIPBE_00133 5.3e-136 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HFCLIPBE_00134 9.2e-195 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HFCLIPBE_00135 2e-209 3.5.1.104 G Polysaccharide deacetylase
HFCLIPBE_00136 7.9e-257 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFCLIPBE_00137 3.1e-72 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFCLIPBE_00138 1.2e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFCLIPBE_00139 2.9e-293 clcA P Voltage gated chloride channel
HFCLIPBE_00140 2.3e-209 U Belongs to the binding-protein-dependent transport system permease family
HFCLIPBE_00141 8e-153 livM U Belongs to the binding-protein-dependent transport system permease family
HFCLIPBE_00142 1.4e-174 natA E Branched-chain amino acid ATP-binding cassette transporter
HFCLIPBE_00143 3e-140 livF E ATPases associated with a variety of cellular activities
HFCLIPBE_00144 1.6e-201 natB E Receptor family ligand binding region
HFCLIPBE_00145 9.8e-85 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFCLIPBE_00146 9.5e-51 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFCLIPBE_00147 7.8e-144 K helix_turn _helix lactose operon repressor
HFCLIPBE_00148 6.7e-219 clcA_2 P Voltage gated chloride channel
HFCLIPBE_00149 2.4e-26 S Protein of unknown function (DUF1653)
HFCLIPBE_00150 2.5e-286 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HFCLIPBE_00151 2.7e-259 G Transporter major facilitator family protein
HFCLIPBE_00153 2.8e-249 yhjE EGP Sugar (and other) transporter
HFCLIPBE_00154 3.8e-201 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HFCLIPBE_00155 3e-50 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
HFCLIPBE_00156 1.4e-144 K helix_turn _helix lactose operon repressor
HFCLIPBE_00158 3.8e-121 natA V ATPases associated with a variety of cellular activities
HFCLIPBE_00159 2.3e-174
HFCLIPBE_00160 1.7e-258 aroP E aromatic amino acid transport protein AroP K03293
HFCLIPBE_00161 1.3e-39 K Transcriptional regulator C-terminal region
HFCLIPBE_00162 3.2e-252 P Sodium/hydrogen exchanger family
HFCLIPBE_00163 3.9e-182 K Periplasmic binding protein-like domain
HFCLIPBE_00164 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HFCLIPBE_00165 2.1e-260 amyE G Bacterial extracellular solute-binding protein
HFCLIPBE_00166 1.7e-70
HFCLIPBE_00167 7.3e-56
HFCLIPBE_00168 1.4e-37
HFCLIPBE_00170 5.3e-127
HFCLIPBE_00171 1.1e-15
HFCLIPBE_00172 3e-08 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFCLIPBE_00173 2.6e-170 rnhA_2 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFCLIPBE_00174 1.2e-17 S DNA packaging
HFCLIPBE_00175 1.1e-61 S EcsC protein family
HFCLIPBE_00176 2.9e-37 S phage minor capsid protein
HFCLIPBE_00177 3e-112 S phage minor capsid protein
HFCLIPBE_00179 5.4e-11
HFCLIPBE_00180 0.0 hsdR 3.1.21.3 L Type III restriction
HFCLIPBE_00181 8.5e-52
HFCLIPBE_00182 2.2e-75 recN L DNA recombination
HFCLIPBE_00183 5.4e-17
HFCLIPBE_00184 7.3e-77
HFCLIPBE_00185 3.4e-09 S Phage tail protein
HFCLIPBE_00187 1.9e-17 S Prophage endopeptidase tail
HFCLIPBE_00188 2e-41 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HFCLIPBE_00190 2.3e-267 cycA E Amino acid permease
HFCLIPBE_00191 9.6e-161 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HFCLIPBE_00192 2.5e-127 thiF 2.7.7.73, 2.7.7.80 H ThiF family
HFCLIPBE_00193 7.4e-26 thiS 2.8.1.10 H ThiS family
HFCLIPBE_00194 4.6e-22 oatA I Acyltransferase family
HFCLIPBE_00195 6.3e-87 phzB S Phenazine biosynthesis protein A/B
HFCLIPBE_00196 2.1e-160 1.1.1.65 C Aldo/keto reductase family
HFCLIPBE_00197 3.6e-244 yhjX EGP Major facilitator Superfamily
HFCLIPBE_00198 2.9e-94 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HFCLIPBE_00199 3.7e-52 K HxlR-like helix-turn-helix
HFCLIPBE_00200 8.4e-63 ydgJ K helix_turn_helix multiple antibiotic resistance protein
HFCLIPBE_00201 0.0 lmrA1 V ABC transporter, ATP-binding protein
HFCLIPBE_00202 0.0 lmrA2 V ABC transporter transmembrane region
HFCLIPBE_00203 3.2e-118 S Fic/DOC family
HFCLIPBE_00204 7.5e-07 S Fic/DOC family
HFCLIPBE_00205 3.7e-192 livK E Receptor family ligand binding region
HFCLIPBE_00206 7.3e-116 U Belongs to the binding-protein-dependent transport system permease family
HFCLIPBE_00207 2.6e-184 livM U Belongs to the binding-protein-dependent transport system permease family
HFCLIPBE_00208 5.2e-148 E Branched-chain amino acid ATP-binding cassette transporter
HFCLIPBE_00209 3e-125 livF E ATPases associated with a variety of cellular activities
HFCLIPBE_00210 5e-64 ywhH S Cys-tRNA(Pro) hydrolase activity
HFCLIPBE_00211 9.1e-32 pilA NU Prokaryotic N-terminal methylation motif
HFCLIPBE_00212 2.3e-30 pilA NU Prokaryotic N-terminal methylation motif
HFCLIPBE_00213 1.5e-12
HFCLIPBE_00214 3.1e-209 macA 1.1.1.61, 1.3.1.32 C Iron-containing alcohol dehydrogenase
HFCLIPBE_00215 9.1e-47 yhbY J CRS1_YhbY
HFCLIPBE_00216 2e-230 rarA L Recombination factor protein RarA
HFCLIPBE_00217 0.0 L DEAD DEAH box helicase
HFCLIPBE_00218 3.4e-202 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
HFCLIPBE_00219 2.1e-105 S Aminoacyl-tRNA editing domain
HFCLIPBE_00220 2.7e-184 gluD E Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00221 1.5e-113 gluC E Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00222 5.3e-153 gluB ET Belongs to the bacterial solute-binding protein 3 family
HFCLIPBE_00223 2.8e-132 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
HFCLIPBE_00224 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HFCLIPBE_00225 4.3e-261 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HFCLIPBE_00226 4e-209 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HFCLIPBE_00227 0.0 clpC O ATPase family associated with various cellular activities (AAA)
HFCLIPBE_00228 8.8e-152 uspA T Belongs to the universal stress protein A family
HFCLIPBE_00229 2.7e-133 S Protein of unknown function (DUF3027)
HFCLIPBE_00230 3.6e-64 cspB K 'Cold-shock' DNA-binding domain
HFCLIPBE_00231 1.3e-276 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HFCLIPBE_00232 2.5e-130 KT Response regulator receiver domain protein
HFCLIPBE_00233 3.4e-49
HFCLIPBE_00235 1.6e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFCLIPBE_00236 4e-30 cspA K 'Cold-shock' DNA-binding domain
HFCLIPBE_00237 1.6e-53 S LytR cell envelope-related transcriptional attenuator
HFCLIPBE_00238 8.3e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFCLIPBE_00239 3.9e-169 moxR S ATPase family associated with various cellular activities (AAA)
HFCLIPBE_00240 1.4e-131 S Protein of unknown function DUF58
HFCLIPBE_00241 9e-56
HFCLIPBE_00242 1.3e-148 S von Willebrand factor (vWF) type A domain
HFCLIPBE_00243 5.4e-120 S von Willebrand factor (vWF) type A domain
HFCLIPBE_00244 3.4e-21
HFCLIPBE_00246 6.1e-163 S PGAP1-like protein
HFCLIPBE_00247 7.1e-267 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HFCLIPBE_00248 0.0 S Lysylphosphatidylglycerol synthase TM region
HFCLIPBE_00249 3.1e-41 hup L Belongs to the bacterial histone-like protein family
HFCLIPBE_00250 5.2e-220 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HFCLIPBE_00252 1e-153 hisN 3.1.3.25 G Inositol monophosphatase family
HFCLIPBE_00253 4.7e-259 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HFCLIPBE_00254 6e-225 arc O AAA ATPase forming ring-shaped complexes
HFCLIPBE_00255 5.2e-98 apl 3.1.3.1 S SNARE associated Golgi protein
HFCLIPBE_00256 3e-117 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HFCLIPBE_00257 1e-168 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFCLIPBE_00258 1.9e-119 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HFCLIPBE_00259 1.3e-42 yunC S Domain of unknown function (DUF1805)
HFCLIPBE_00260 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFCLIPBE_00261 1.8e-253 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
HFCLIPBE_00262 1.3e-226 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFCLIPBE_00263 2.5e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFCLIPBE_00264 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HFCLIPBE_00265 1.1e-91 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HFCLIPBE_00266 3.6e-155 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HFCLIPBE_00267 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HFCLIPBE_00268 1.5e-225 carA 6.3.5.5 F Belongs to the CarA family
HFCLIPBE_00269 1.8e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFCLIPBE_00270 2.8e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFCLIPBE_00271 5.8e-189 1.1.3.46 C FMN-dependent dehydrogenase
HFCLIPBE_00272 8.9e-231 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFCLIPBE_00273 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFCLIPBE_00274 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFCLIPBE_00275 2.7e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFCLIPBE_00278 1.1e-272 5.4.3.8 H Aminotransferase class-III
HFCLIPBE_00280 9.4e-196 E Bacterial extracellular solute-binding protein
HFCLIPBE_00281 5.6e-133 potC U Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00282 7.9e-164 potB U Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00283 1.3e-162 potA 3.6.3.31 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFCLIPBE_00284 1.5e-70 asnC K helix_turn_helix ASNC type
HFCLIPBE_00285 4.7e-244 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Aldehyde dehydrogenase family
HFCLIPBE_00286 1e-207 M Glycosyl transferase 4-like domain
HFCLIPBE_00287 2.1e-225 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFCLIPBE_00288 8.6e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HFCLIPBE_00289 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HFCLIPBE_00294 7.9e-11 S HicB family
HFCLIPBE_00295 1.6e-139 3.2.1.4 GH5,GH9 G CBD_II
HFCLIPBE_00296 5.2e-07
HFCLIPBE_00297 1.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HFCLIPBE_00298 4e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFCLIPBE_00299 8.6e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HFCLIPBE_00300 1.8e-237 purD 6.3.4.13 F Belongs to the GARS family
HFCLIPBE_00301 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HFCLIPBE_00302 1.9e-256 S Putative esterase
HFCLIPBE_00303 0.0 lysX S Uncharacterised conserved protein (DUF2156)
HFCLIPBE_00304 2.1e-115 P Zinc-uptake complex component A periplasmic
HFCLIPBE_00305 9.8e-65 zur P Belongs to the Fur family
HFCLIPBE_00306 1e-218 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFCLIPBE_00307 1.4e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFCLIPBE_00308 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFCLIPBE_00309 8e-258 macB_8 V MacB-like periplasmic core domain
HFCLIPBE_00310 2.5e-172 M Conserved repeat domain
HFCLIPBE_00311 2.3e-124 V ATPases associated with a variety of cellular activities
HFCLIPBE_00313 3.4e-198 ybiR P Citrate transporter
HFCLIPBE_00314 0.0 G Alpha-L-arabinofuranosidase C-terminal domain
HFCLIPBE_00318 1e-179 4.2.1.48 S Domain of unknown function (DUF4392)
HFCLIPBE_00319 0.0 bccA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Biotin carboxylase C-terminal domain
HFCLIPBE_00320 0.0 ybgK E Allophanate hydrolase subunit 2
HFCLIPBE_00321 5.2e-134 lamB S LamB/YcsF family
HFCLIPBE_00322 1.8e-148 S Protein of unknown function (DUF1445)
HFCLIPBE_00323 2e-172 pabC 2.6.1.42, 4.1.3.38 EH Amino-transferase class IV
HFCLIPBE_00324 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFCLIPBE_00325 6e-233 dgt 3.1.5.1 F Phosphohydrolase-associated domain
HFCLIPBE_00326 1.3e-257 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFCLIPBE_00327 4e-268 yhdG E aromatic amino acid transport protein AroP K03293
HFCLIPBE_00328 2e-91 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HFCLIPBE_00329 6e-96 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFCLIPBE_00330 7.6e-94 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HFCLIPBE_00331 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HFCLIPBE_00332 6.4e-221 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HFCLIPBE_00333 2.2e-190 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HFCLIPBE_00334 8.4e-194 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFCLIPBE_00335 1.2e-180 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFCLIPBE_00336 7.7e-99 sapF E ATPases associated with a variety of cellular activities
HFCLIPBE_00337 2.7e-103 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
HFCLIPBE_00338 1.6e-112 EP Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00339 6e-145 P Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00340 4.1e-282 E ABC transporter, substrate-binding protein, family 5
HFCLIPBE_00341 1.7e-137 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HFCLIPBE_00342 2.3e-227 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFCLIPBE_00343 8.1e-239 G Bacterial extracellular solute-binding protein
HFCLIPBE_00344 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HFCLIPBE_00345 1.9e-157 K Periplasmic binding protein domain
HFCLIPBE_00346 3.3e-142 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HFCLIPBE_00347 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFCLIPBE_00348 5.3e-111
HFCLIPBE_00349 1.9e-92
HFCLIPBE_00350 5.6e-195
HFCLIPBE_00351 1.9e-124 ytrE V ABC transporter
HFCLIPBE_00352 3.6e-189 V N-Acetylmuramoyl-L-alanine amidase
HFCLIPBE_00353 1.2e-126 K helix_turn_helix, Lux Regulon
HFCLIPBE_00354 1.8e-208 2.7.13.3 T Histidine kinase
HFCLIPBE_00355 1.1e-139 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
HFCLIPBE_00356 1.7e-118 yecS E Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00357 5.8e-145 pknD ET ABC transporter, substrate-binding protein, family 3
HFCLIPBE_00358 6.7e-144 pknD ET ABC transporter, substrate-binding protein, family 3
HFCLIPBE_00359 4.3e-75 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFCLIPBE_00361 6.8e-124 usp 3.5.1.28 CBM50 D CHAP domain protein
HFCLIPBE_00363 1.4e-154 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HFCLIPBE_00364 2.3e-158 ftsE D Cell division ATP-binding protein FtsE
HFCLIPBE_00365 4.4e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFCLIPBE_00367 7.8e-119 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HFCLIPBE_00368 1.6e-129 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HFCLIPBE_00369 8.3e-47 ypaA S Protein of unknown function (DUF1304)
HFCLIPBE_00370 1.1e-19 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HFCLIPBE_00371 1.6e-246 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HFCLIPBE_00372 1.7e-150 map 3.4.11.18 E Methionine aminopeptidase
HFCLIPBE_00373 1.5e-97 S Short repeat of unknown function (DUF308)
HFCLIPBE_00374 0.0 pepO 3.4.24.71 O Peptidase family M13
HFCLIPBE_00375 8.8e-57 L Single-strand binding protein family
HFCLIPBE_00376 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFCLIPBE_00377 1.6e-288 G Bacterial extracellular solute-binding protein
HFCLIPBE_00378 7.2e-178 G Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00379 4.6e-166 G Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00380 8.4e-109 S Protein of unknown function, DUF624
HFCLIPBE_00381 1.8e-166 K helix_turn _helix lactose operon repressor
HFCLIPBE_00382 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HFCLIPBE_00383 2.1e-60
HFCLIPBE_00384 1.8e-225 recD2 3.6.4.12 L PIF1-like helicase
HFCLIPBE_00385 3.2e-140 supH S Sucrose-6F-phosphate phosphohydrolase
HFCLIPBE_00386 7.5e-126 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HFCLIPBE_00387 6.7e-298 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFCLIPBE_00388 9.5e-292 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HFCLIPBE_00389 1.1e-188 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HFCLIPBE_00390 1.5e-94 ywlC 2.7.7.87 J Belongs to the SUA5 family
HFCLIPBE_00391 3.9e-146 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFCLIPBE_00392 1.1e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFCLIPBE_00393 1.2e-34 rpmE J Binds the 23S rRNA
HFCLIPBE_00395 1.1e-111 ykoE S ABC-type cobalt transport system, permease component
HFCLIPBE_00396 1.5e-154 yocS S SBF-like CPA transporter family (DUF4137)
HFCLIPBE_00398 3.7e-61 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFCLIPBE_00399 1.1e-95 ywrO S Flavodoxin-like fold
HFCLIPBE_00400 1.6e-41 K Acetyltransferase (GNAT) domain
HFCLIPBE_00401 2e-222 aspB E Aminotransferase class-V
HFCLIPBE_00402 1.5e-66 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HFCLIPBE_00403 1.3e-120 nrtR 3.6.1.55 F NUDIX hydrolase
HFCLIPBE_00404 1.2e-246 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HFCLIPBE_00405 4.1e-286 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HFCLIPBE_00406 6.5e-143 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
HFCLIPBE_00407 1.1e-178 iscS1 2.8.1.7 E Aminotransferase class-V
HFCLIPBE_00408 9.1e-172 rarA L Recombination factor protein RarA
HFCLIPBE_00409 1.3e-95 metI P Psort location CytoplasmicMembrane, score 9.99
HFCLIPBE_00410 4.3e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFCLIPBE_00411 1.2e-157 metQ M NLPA lipoprotein
HFCLIPBE_00412 5e-195 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFCLIPBE_00413 1e-218 mtnE 2.6.1.83 E Aminotransferase class I and II
HFCLIPBE_00414 6.9e-193 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
HFCLIPBE_00415 4.6e-188 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HFCLIPBE_00416 3.4e-87 L HNH endonuclease
HFCLIPBE_00417 1.5e-118 L DNA mismatch repair enzyme MutH
HFCLIPBE_00418 2.5e-129 mutH L DNA mismatch repair enzyme MutH
HFCLIPBE_00419 1.6e-125 S Protein of unknown function (DUF1524)
HFCLIPBE_00420 2e-128 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
HFCLIPBE_00421 1.8e-96 S Pyridoxamine 5'-phosphate oxidase
HFCLIPBE_00422 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
HFCLIPBE_00423 5e-261 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HFCLIPBE_00424 2.9e-138 S Sulfite exporter TauE/SafE
HFCLIPBE_00425 0.0 yjjK S ATP-binding cassette protein, ChvD family
HFCLIPBE_00427 3.7e-163 tesB I Thioesterase-like superfamily
HFCLIPBE_00428 2.3e-77 S Protein of unknown function (DUF3180)
HFCLIPBE_00429 7.9e-95 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFCLIPBE_00430 4e-116 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HFCLIPBE_00431 2.6e-78 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HFCLIPBE_00432 2.2e-137 folK 1.13.11.81, 2.5.1.15, 2.6.1.85, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFCLIPBE_00433 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFCLIPBE_00434 1.7e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFCLIPBE_00435 2.6e-136 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFCLIPBE_00436 8.3e-207 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
HFCLIPBE_00437 4.5e-230 epsG M Glycosyl transferase family 21
HFCLIPBE_00438 4.7e-235 S AI-2E family transporter
HFCLIPBE_00439 1.3e-176 3.4.14.13 M Glycosyltransferase like family 2
HFCLIPBE_00440 1.1e-201 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
HFCLIPBE_00441 7.8e-49 K WYL domain
HFCLIPBE_00442 8.1e-13
HFCLIPBE_00446 5.4e-18 S Domain of unknown function (DUF4190)
HFCLIPBE_00447 0.0 malZ 3.2.1.20 GH31 G Alpha amylase, catalytic domain
HFCLIPBE_00448 3.3e-137 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFCLIPBE_00450 9.9e-97 ptpA 3.1.3.48 T low molecular weight
HFCLIPBE_00451 2.5e-124 folA 1.5.1.3 H dihydrofolate reductase
HFCLIPBE_00452 1.4e-161 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFCLIPBE_00453 1e-69 attW O OsmC-like protein
HFCLIPBE_00454 2.2e-185 T Universal stress protein family
HFCLIPBE_00455 3.6e-76 M NlpC/P60 family
HFCLIPBE_00456 6.7e-88 usp 3.5.1.28 CBM50 S CHAP domain
HFCLIPBE_00457 1e-196 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HFCLIPBE_00458 1e-212 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G Phosphomannose isomerase type I
HFCLIPBE_00459 1.3e-35
HFCLIPBE_00460 9.5e-154 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HFCLIPBE_00461 9.3e-108 phoU P Plays a role in the regulation of phosphate uptake
HFCLIPBE_00462 7.1e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFCLIPBE_00463 1.1e-119 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HFCLIPBE_00464 2.7e-202 S ATPase domain predominantly from Archaea
HFCLIPBE_00465 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HFCLIPBE_00468 8.6e-22
HFCLIPBE_00470 4.9e-294 S Domain of unknown function (DUF4037)
HFCLIPBE_00471 4.9e-99 S Protein of unknown function (DUF4125)
HFCLIPBE_00472 2.1e-238 S alpha beta
HFCLIPBE_00474 1e-177 pspC KT PspC domain
HFCLIPBE_00475 2.4e-189 tcsS3 KT PspC domain
HFCLIPBE_00476 9.1e-111 degU K helix_turn_helix, Lux Regulon
HFCLIPBE_00477 2.4e-103 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HFCLIPBE_00480 3e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFCLIPBE_00481 1.1e-170 I Diacylglycerol kinase catalytic domain
HFCLIPBE_00482 6.5e-138 arbG K CAT RNA binding domain
HFCLIPBE_00483 0.0 crr G pts system, glucose-specific IIABC component
HFCLIPBE_00484 9.1e-306 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HFCLIPBE_00485 3.3e-145 E Sodium:solute symporter family
HFCLIPBE_00486 4.1e-13
HFCLIPBE_00487 8.3e-70 2.7.1.89 M PFAM Choline ethanolamine kinase
HFCLIPBE_00488 1.3e-38 2.7.1.89 M Phosphotransferase enzyme family
HFCLIPBE_00489 1.3e-87 6.3.5.6, 6.3.5.7 J Amidase
HFCLIPBE_00490 2e-247 gabT 2.6.1.19, 2.6.1.22 H Aminotransferase class-III
HFCLIPBE_00491 1.2e-52 yidP K UTRA
HFCLIPBE_00492 5.9e-71 K helix_turn_helix, mercury resistance
HFCLIPBE_00493 8.2e-199 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HFCLIPBE_00494 6.5e-159 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFCLIPBE_00495 1.9e-144 V ATPases associated with a variety of cellular activities
HFCLIPBE_00496 0.0 V FtsX-like permease family
HFCLIPBE_00497 9.1e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFCLIPBE_00498 5.9e-236 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
HFCLIPBE_00500 2.8e-90
HFCLIPBE_00501 7e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFCLIPBE_00502 4.6e-204 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HFCLIPBE_00503 1.3e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFCLIPBE_00504 3.3e-74 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFCLIPBE_00505 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFCLIPBE_00506 1.2e-183 nusA K Participates in both transcription termination and antitermination
HFCLIPBE_00507 2.6e-81
HFCLIPBE_00509 2e-134 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFCLIPBE_00510 1.6e-61 rplQ J Ribosomal protein L17
HFCLIPBE_00511 2e-183 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFCLIPBE_00512 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFCLIPBE_00513 1.2e-61 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFCLIPBE_00514 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HFCLIPBE_00515 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFCLIPBE_00516 7.4e-95 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFCLIPBE_00517 1.1e-242 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFCLIPBE_00518 4.4e-69 rplO J binds to the 23S rRNA
HFCLIPBE_00519 4.2e-23 rpmD J Ribosomal protein L30p/L7e
HFCLIPBE_00520 7.9e-97 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFCLIPBE_00521 3.4e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFCLIPBE_00522 1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFCLIPBE_00523 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFCLIPBE_00524 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFCLIPBE_00525 7.8e-100 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFCLIPBE_00526 3.7e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFCLIPBE_00527 2.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFCLIPBE_00528 1e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFCLIPBE_00529 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
HFCLIPBE_00530 6.8e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFCLIPBE_00531 4.4e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFCLIPBE_00532 3.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFCLIPBE_00533 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFCLIPBE_00534 2.3e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFCLIPBE_00535 4.4e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFCLIPBE_00536 2.2e-114 rplD J Forms part of the polypeptide exit tunnel
HFCLIPBE_00537 5.2e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFCLIPBE_00538 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
HFCLIPBE_00539 2.9e-156 lipA I Hydrolase, alpha beta domain protein
HFCLIPBE_00540 9.6e-50 K Bacterial regulatory proteins, tetR family
HFCLIPBE_00541 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HFCLIPBE_00542 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HFCLIPBE_00543 5.3e-81 rpsI J Belongs to the universal ribosomal protein uS9 family
HFCLIPBE_00544 2.9e-76 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFCLIPBE_00545 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HFCLIPBE_00546 1e-77
HFCLIPBE_00547 2.5e-86 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HFCLIPBE_00550 5.4e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFCLIPBE_00551 1.5e-201 dapC E Aminotransferase class I and II
HFCLIPBE_00552 2.5e-58 fdxA C 4Fe-4S binding domain
HFCLIPBE_00553 5.9e-254 E aromatic amino acid transport protein AroP K03293
HFCLIPBE_00554 5e-173 murB 1.3.1.98 M Cell wall formation
HFCLIPBE_00555 1.9e-25 rpmG J Ribosomal protein L33
HFCLIPBE_00559 3.2e-195 pat 2.6.1.9 E Aminotransferase class I and II
HFCLIPBE_00560 0.0 E Transglutaminase-like superfamily
HFCLIPBE_00561 6.3e-142 moxR S ATPase family associated with various cellular activities (AAA)
HFCLIPBE_00562 3.3e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFCLIPBE_00563 2.3e-76
HFCLIPBE_00564 1.6e-80 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
HFCLIPBE_00565 1e-60 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HFCLIPBE_00566 1.7e-27 fmdB S Putative regulatory protein
HFCLIPBE_00567 1.4e-39 flgA NO SAF
HFCLIPBE_00568 2e-26
HFCLIPBE_00569 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HFCLIPBE_00570 8.1e-83 T Forkhead associated domain
HFCLIPBE_00571 3.2e-33 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFCLIPBE_00572 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFCLIPBE_00573 6.7e-148 3.4.22.70 M Sortase family
HFCLIPBE_00574 9.6e-70 M domain protein
HFCLIPBE_00575 0.0 M cell wall anchor domain protein
HFCLIPBE_00577 5.4e-195 pbuO S Permease family
HFCLIPBE_00578 2.5e-61 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HFCLIPBE_00579 4.7e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFCLIPBE_00580 9.7e-162 pstA P Phosphate transport system permease
HFCLIPBE_00581 9.5e-151 pstC P probably responsible for the translocation of the substrate across the membrane
HFCLIPBE_00582 1.2e-192 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HFCLIPBE_00583 3e-125 KT Transcriptional regulatory protein, C terminal
HFCLIPBE_00584 2.1e-165 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HFCLIPBE_00585 3.2e-116 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFCLIPBE_00586 3e-224 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HFCLIPBE_00587 1.6e-213 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HFCLIPBE_00588 2.3e-256 pepC 3.4.22.40 E Peptidase C1-like family
HFCLIPBE_00589 2.3e-28 D nuclear chromosome segregation
HFCLIPBE_00590 1.2e-113 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HFCLIPBE_00591 9.7e-116 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HFCLIPBE_00592 2.4e-176 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HFCLIPBE_00593 5.5e-268 yegQ O Peptidase family U32 C-terminal domain
HFCLIPBE_00594 1.5e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HFCLIPBE_00595 1.6e-27 S Predicted membrane protein (DUF2207)
HFCLIPBE_00596 5.8e-228 S Predicted membrane protein (DUF2207)
HFCLIPBE_00597 3.3e-87 lemA S LemA family
HFCLIPBE_00598 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HFCLIPBE_00599 1.9e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFCLIPBE_00600 3.2e-97
HFCLIPBE_00602 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
HFCLIPBE_00603 3.4e-50 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFCLIPBE_00604 1.3e-145 S CAAX protease self-immunity
HFCLIPBE_00605 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HFCLIPBE_00606 2.4e-295 pccB I Carboxyl transferase domain
HFCLIPBE_00607 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HFCLIPBE_00608 5.8e-85 bioY S BioY family
HFCLIPBE_00609 2.3e-135 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HFCLIPBE_00610 2e-305
HFCLIPBE_00611 5.1e-126 QT PucR C-terminal helix-turn-helix domain
HFCLIPBE_00612 3.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFCLIPBE_00613 2e-71 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFCLIPBE_00614 1.1e-118 nusG K Participates in transcription elongation, termination and antitermination
HFCLIPBE_00615 4.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFCLIPBE_00617 1e-226 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HFCLIPBE_00618 1.2e-197 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFCLIPBE_00619 8.1e-278 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFCLIPBE_00620 4.4e-39 rpmA J Ribosomal L27 protein
HFCLIPBE_00621 1.1e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HFCLIPBE_00622 0.0 rne 3.1.26.12 J Ribonuclease E/G family
HFCLIPBE_00623 2.7e-211 dapE 3.5.1.18 E Peptidase dimerisation domain
HFCLIPBE_00624 6.7e-157 mdcF S Transporter, auxin efflux carrier (AEC) family protein
HFCLIPBE_00625 1.9e-259 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HFCLIPBE_00626 3.3e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFCLIPBE_00627 8.5e-235 hom 1.1.1.3 E Homoserine dehydrogenase
HFCLIPBE_00628 4.2e-284 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFCLIPBE_00629 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HFCLIPBE_00630 3.6e-237 mmuP E amino acid
HFCLIPBE_00631 4.8e-61 psp1 3.5.99.10 J Endoribonuclease L-PSP
HFCLIPBE_00632 0.0 sprF 4.6.1.1 M Cell surface antigen C-terminus
HFCLIPBE_00634 4.2e-138 trxA2 O Tetratricopeptide repeat
HFCLIPBE_00635 5.8e-159
HFCLIPBE_00636 2.2e-119
HFCLIPBE_00637 2.2e-142 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HFCLIPBE_00638 1.4e-127 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HFCLIPBE_00639 1.5e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HFCLIPBE_00640 6.8e-281 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFCLIPBE_00641 5.5e-156 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFCLIPBE_00642 2.8e-304 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFCLIPBE_00643 7.7e-141 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFCLIPBE_00644 2.3e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFCLIPBE_00645 5e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFCLIPBE_00646 2.6e-141 atpB C it plays a direct role in the translocation of protons across the membrane
HFCLIPBE_00647 1.5e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFCLIPBE_00650 8.7e-263 E aromatic amino acid transport protein AroP K03293
HFCLIPBE_00651 5.3e-176 ansA 3.5.1.1 EJ Asparaginase
HFCLIPBE_00652 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HFCLIPBE_00653 8.9e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HFCLIPBE_00654 5.3e-96 mntP P Probably functions as a manganese efflux pump
HFCLIPBE_00655 2.1e-97
HFCLIPBE_00656 3.2e-130 KT Transcriptional regulatory protein, C terminal
HFCLIPBE_00657 1.7e-125 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFCLIPBE_00658 2.3e-223 E Bacterial extracellular solute-binding proteins, family 5 Middle
HFCLIPBE_00659 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFCLIPBE_00660 2.5e-270 S domain protein
HFCLIPBE_00661 5.3e-63 tyrA 5.4.99.5 E Chorismate mutase type II
HFCLIPBE_00662 1.7e-266 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HFCLIPBE_00663 1.1e-292 5.4.99.9 H Flavin containing amine oxidoreductase
HFCLIPBE_00664 1.7e-51 S Protein of unknown function (DUF2469)
HFCLIPBE_00665 8.9e-154 2.3.1.57 J Acetyltransferase (GNAT) domain
HFCLIPBE_00666 2.1e-285 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFCLIPBE_00667 6.6e-287 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFCLIPBE_00668 7.7e-35 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFCLIPBE_00669 1.9e-48 M LPXTG cell wall anchor motif
HFCLIPBE_00670 1.1e-43 M cell septum assembly
HFCLIPBE_00671 1.4e-70 3.4.22.70 M Sortase family
HFCLIPBE_00672 1.9e-137 spoU 2.1.1.185 J RNA methyltransferase TrmH family
HFCLIPBE_00673 2.8e-107 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFCLIPBE_00674 4.7e-156 rmuC S RmuC family
HFCLIPBE_00675 3.6e-42 csoR S Metal-sensitive transcriptional repressor
HFCLIPBE_00676 0.0 pacS 3.6.3.54 P E1-E2 ATPase
HFCLIPBE_00677 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFCLIPBE_00678 1.9e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFCLIPBE_00679 5.7e-41 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HFCLIPBE_00680 4.4e-62 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HFCLIPBE_00681 1.1e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HFCLIPBE_00682 5.4e-211 vbsD V MatE
HFCLIPBE_00683 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HFCLIPBE_00684 4.1e-142 P Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00685 2e-155 P Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00686 3.1e-243 G Bacterial extracellular solute-binding protein
HFCLIPBE_00687 3.1e-168 K Psort location Cytoplasmic, score
HFCLIPBE_00688 5.1e-108 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HFCLIPBE_00689 1.5e-12
HFCLIPBE_00691 1.7e-139 draG O ADP-ribosylglycohydrolase
HFCLIPBE_00692 1.5e-107 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Crp-like helix-turn-helix domain
HFCLIPBE_00693 3.8e-48 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
HFCLIPBE_00694 8.9e-34 copZ P Heavy-metal-associated domain
HFCLIPBE_00695 6.5e-303 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HFCLIPBE_00697 1.6e-80
HFCLIPBE_00698 3.1e-107 ydcV U Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00699 7.6e-124 ydcU U Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00700 1.2e-193 ydcS E Bacterial extracellular solute-binding protein
HFCLIPBE_00701 4.3e-133 ydcT 3.6.3.31 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFCLIPBE_00702 2.9e-66 K Transcriptional regulator
HFCLIPBE_00703 2e-73 K Transcriptional regulator
HFCLIPBE_00704 2.1e-82 3.4.21.105 M Sortase family
HFCLIPBE_00705 1.7e-85
HFCLIPBE_00706 5.3e-76 3.4.21.105 M Sortase family
HFCLIPBE_00707 1.9e-53
HFCLIPBE_00708 5.2e-221 M LPXTG cell wall anchor motif
HFCLIPBE_00710 1.1e-234 Q von Willebrand factor (vWF) type A domain
HFCLIPBE_00711 4.3e-36 acyP 3.6.1.7 C Acylphosphatase
HFCLIPBE_00712 4.3e-123 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HFCLIPBE_00713 2.5e-152 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFCLIPBE_00714 1.4e-101
HFCLIPBE_00716 7.8e-121 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HFCLIPBE_00717 1.6e-232 glf 5.4.99.9 M UDP-galactopyranose mutase
HFCLIPBE_00718 9.1e-217 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
HFCLIPBE_00719 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HFCLIPBE_00720 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HFCLIPBE_00721 5.2e-158 S Calcineurin-like phosphoesterase
HFCLIPBE_00724 4.9e-84 hsp20 O Hsp20/alpha crystallin family
HFCLIPBE_00726 4.2e-190 cat P Cation efflux family
HFCLIPBE_00727 4.6e-240 S Psort location Cytoplasmic, score 8.87
HFCLIPBE_00728 1e-82 S Domain of unknown function (DUF4194)
HFCLIPBE_00729 0.0 S Psort location Cytoplasmic, score 8.87
HFCLIPBE_00730 1.1e-159 S Psort location Cytoplasmic, score 8.87
HFCLIPBE_00731 9.5e-89 bcp 1.11.1.15 O Redoxin
HFCLIPBE_00732 6.1e-114
HFCLIPBE_00734 1.3e-40 2.7.11.1 S RDD family
HFCLIPBE_00735 0.0 S Psort location CytoplasmicMembrane, score 9.99
HFCLIPBE_00736 5.3e-206 V ABC transporter permease
HFCLIPBE_00737 2e-118 V ABC transporter
HFCLIPBE_00738 1.2e-132 T HD domain
HFCLIPBE_00739 2.8e-149 S Glutamine amidotransferase domain
HFCLIPBE_00740 0.0 kup P Transport of potassium into the cell
HFCLIPBE_00741 2.6e-172 tatD L TatD related DNase
HFCLIPBE_00742 6.5e-239 pepC 3.4.22.40 E Peptidase C1-like family
HFCLIPBE_00743 6.9e-54 ydeP K HxlR-like helix-turn-helix
HFCLIPBE_00744 5.6e-107 S NAD(P)H-binding
HFCLIPBE_00745 3.6e-168 S Appr-1'-p processing enzyme
HFCLIPBE_00746 1.7e-190 K NAD-dependent protein deacetylase, SIR2 family
HFCLIPBE_00747 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFCLIPBE_00748 4.6e-58
HFCLIPBE_00749 2e-17
HFCLIPBE_00750 1.9e-165 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFCLIPBE_00751 3.2e-285 pmt 2.4.1.109 GT39 O C-terminal four TMM region of protein-O-mannosyltransferase
HFCLIPBE_00752 0.0 M probably involved in cell wall
HFCLIPBE_00753 2.3e-160 3.2.1.14 GH18 S Carbohydrate binding domain
HFCLIPBE_00754 8e-152 T Diguanylate cyclase, GGDEF domain
HFCLIPBE_00755 1e-127 dedA S SNARE associated Golgi protein
HFCLIPBE_00757 5.1e-07 S Sec23/Sec24 zinc finger
HFCLIPBE_00758 9.7e-113 mgtC S MgtC family
HFCLIPBE_00759 3e-88 S HAD hydrolase, family IA, variant 3
HFCLIPBE_00761 2.2e-83 hspR K transcriptional regulator, MerR family
HFCLIPBE_00762 1.4e-157 dnaJ1 O DnaJ molecular chaperone homology domain
HFCLIPBE_00763 8.1e-63 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFCLIPBE_00764 0.0 dnaK O Heat shock 70 kDa protein
HFCLIPBE_00765 1.2e-299 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
HFCLIPBE_00766 1e-174 K Psort location Cytoplasmic, score
HFCLIPBE_00767 2e-114 traX S TraX protein
HFCLIPBE_00768 7.2e-114 S HAD-hyrolase-like
HFCLIPBE_00769 2.1e-291 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
HFCLIPBE_00770 4e-205 malE G Bacterial extracellular solute-binding protein
HFCLIPBE_00771 3.1e-235 malF G Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00772 6.6e-154 malG G Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00773 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HFCLIPBE_00774 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HFCLIPBE_00775 8.2e-99 S Protein of unknown function, DUF624
HFCLIPBE_00776 6.1e-157 rafG G ABC transporter permease
HFCLIPBE_00777 8.5e-151 msmF G Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00778 1.6e-159 K Psort location Cytoplasmic, score
HFCLIPBE_00779 4.6e-228 amyE G Bacterial extracellular solute-binding protein
HFCLIPBE_00780 3.5e-111 G Phosphoglycerate mutase family
HFCLIPBE_00781 2.7e-11 S Protein of unknown function (DUF4235)
HFCLIPBE_00782 1.5e-117 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HFCLIPBE_00783 1.2e-39
HFCLIPBE_00784 1.2e-152 EGP Major facilitator Superfamily
HFCLIPBE_00785 4.1e-129 yvgN S Aldo/keto reductase family
HFCLIPBE_00786 1.5e-12
HFCLIPBE_00787 5e-110 3.1.1.3 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HFCLIPBE_00788 1.5e-11 CP_1020 S zinc finger
HFCLIPBE_00789 7.1e-69 S zinc finger
HFCLIPBE_00790 1.3e-48 lrp_3 K helix_turn_helix ASNC type
HFCLIPBE_00791 2.1e-195 opuCC P Substrate binding domain of ABC-type glycine betaine transport system
HFCLIPBE_00792 6.8e-103 proV E ATPases associated with a variety of cellular activities
HFCLIPBE_00793 2.1e-156 1.1.1.399, 1.1.1.95 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HFCLIPBE_00794 3.9e-179 G Transporter major facilitator family
HFCLIPBE_00795 5.3e-177 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFCLIPBE_00796 1.6e-158 natB E Receptor family ligand binding region
HFCLIPBE_00797 2.2e-75 K Transcriptional regulator
HFCLIPBE_00798 2.8e-209 dgdA 2.6.1.11, 2.6.1.17, 4.1.1.64 E Aminotransferase class-III
HFCLIPBE_00799 1e-53 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HFCLIPBE_00802 1.7e-193 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFCLIPBE_00803 2.8e-70 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
HFCLIPBE_00804 1.8e-119 yeaZ 2.3.1.234 O Glycoprotease family
HFCLIPBE_00805 1.2e-75 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
HFCLIPBE_00806 6.6e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
HFCLIPBE_00807 1.3e-146 comE S Competence protein
HFCLIPBE_00808 7.8e-26 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
HFCLIPBE_00809 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFCLIPBE_00810 1.3e-103 ET Bacterial periplasmic substrate-binding proteins
HFCLIPBE_00811 6.5e-168 corA P CorA-like Mg2+ transporter protein
HFCLIPBE_00814 1.7e-57 cadD P Cadmium resistance transporter
HFCLIPBE_00815 2.3e-47
HFCLIPBE_00816 5.1e-112 S HAD hydrolase, family IA, variant 3
HFCLIPBE_00817 2.4e-147 EG EamA-like transporter family
HFCLIPBE_00818 1.9e-68 pdxH S Pfam:Pyridox_oxidase
HFCLIPBE_00819 4.5e-233 pflA 1.97.1.4 O Radical SAM superfamily
HFCLIPBE_00820 5.5e-232 S AMMECR1
HFCLIPBE_00821 3.6e-132 3.1.3.85 G Phosphoglycerate mutase family
HFCLIPBE_00822 7.3e-63 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFCLIPBE_00823 1.4e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFCLIPBE_00825 7.7e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFCLIPBE_00826 9.1e-128 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFCLIPBE_00827 1.6e-80
HFCLIPBE_00828 1.9e-229 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFCLIPBE_00829 3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
HFCLIPBE_00830 1.4e-52 K helix_turn_helix gluconate operon transcriptional repressor
HFCLIPBE_00831 1.8e-116 S Haloacid dehalogenase-like hydrolase
HFCLIPBE_00832 2.8e-244 recN L May be involved in recombinational repair of damaged DNA
HFCLIPBE_00833 7.9e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFCLIPBE_00834 7.5e-248 trkB P Cation transport protein
HFCLIPBE_00835 8.2e-107 trkA P TrkA-N domain
HFCLIPBE_00836 6.4e-07
HFCLIPBE_00837 4.1e-104 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HFCLIPBE_00839 2.1e-143 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HFCLIPBE_00840 2.6e-145 L Tetratricopeptide repeat
HFCLIPBE_00841 2.2e-246 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFCLIPBE_00844 4.5e-101 S Putative ABC-transporter type IV
HFCLIPBE_00845 4.2e-76 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFCLIPBE_00846 1.4e-265 argH 4.3.2.1 E argininosuccinate lyase
HFCLIPBE_00847 5e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFCLIPBE_00848 1.4e-68 argR K Regulates arginine biosynthesis genes
HFCLIPBE_00849 4.7e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFCLIPBE_00850 1.3e-232 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HFCLIPBE_00851 1.8e-173 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HFCLIPBE_00852 2.2e-210 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HFCLIPBE_00853 1e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HFCLIPBE_00854 2.2e-44
HFCLIPBE_00855 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HFCLIPBE_00856 3.5e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFCLIPBE_00857 2.7e-163 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFCLIPBE_00858 3.7e-102 ywlG S Protein of unknown function (DUF436)
HFCLIPBE_00862 0.0 cbiQ P ATPases associated with a variety of cellular activities
HFCLIPBE_00863 1.4e-106 ykoE S ABC-type cobalt transport system, permease component
HFCLIPBE_00864 3.6e-106 ykoE S ABC-type cobalt transport system, permease component
HFCLIPBE_00865 8.5e-194
HFCLIPBE_00866 1.8e-120 ytrE V ATPases associated with a variety of cellular activities
HFCLIPBE_00867 2.2e-172 V N-Acetylmuramoyl-L-alanine amidase
HFCLIPBE_00868 1.1e-128
HFCLIPBE_00869 8.5e-131
HFCLIPBE_00870 6.2e-96
HFCLIPBE_00871 6.8e-259 argE E Peptidase dimerisation domain
HFCLIPBE_00872 8e-90 S Protein of unknown function (DUF3043)
HFCLIPBE_00873 9.2e-270 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HFCLIPBE_00874 1.3e-145 S Domain of unknown function (DUF4191)
HFCLIPBE_00875 1.3e-281 glnA 6.3.1.2 E glutamine synthetase
HFCLIPBE_00876 2.1e-195 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HFCLIPBE_00877 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFCLIPBE_00878 0.0 S Tetratricopeptide repeat
HFCLIPBE_00879 8.4e-251 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFCLIPBE_00880 1.3e-108 bioM P ATPases associated with a variety of cellular activities
HFCLIPBE_00881 2.2e-181 E Aminotransferase class I and II
HFCLIPBE_00882 2.6e-138 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
HFCLIPBE_00883 4.4e-170 S Glycosyltransferase, group 2 family protein
HFCLIPBE_00884 4.2e-82 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFCLIPBE_00885 0.0 ecfA GP ABC transporter, ATP-binding protein
HFCLIPBE_00886 2e-56 yneG S Domain of unknown function (DUF4186)
HFCLIPBE_00887 6.1e-47
HFCLIPBE_00888 7.4e-34
HFCLIPBE_00890 1.9e-40
HFCLIPBE_00891 1.5e-12
HFCLIPBE_00892 1.9e-40
HFCLIPBE_00895 2.2e-159 pilT NU Type II/IV secretion system protein
HFCLIPBE_00898 3e-28 pilA NU Prokaryotic N-terminal methylation motif
HFCLIPBE_00899 4.2e-230 G MFS/sugar transport protein
HFCLIPBE_00901 1.5e-73 K Psort location Cytoplasmic, score 8.87
HFCLIPBE_00902 3.3e-231 pip S YhgE Pip domain protein
HFCLIPBE_00903 3.3e-291 pip S YhgE Pip domain protein
HFCLIPBE_00906 1.4e-209 S Putative ABC-transporter type IV
HFCLIPBE_00907 4.6e-191 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFCLIPBE_00908 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFCLIPBE_00909 4.1e-74 nrdI F Probably involved in ribonucleotide reductase function
HFCLIPBE_00910 1.6e-30 nrdH O Glutaredoxin
HFCLIPBE_00911 2.7e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFCLIPBE_00912 2.8e-230 EGP Major facilitator Superfamily
HFCLIPBE_00913 2e-141 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HFCLIPBE_00914 4.5e-15 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HFCLIPBE_00915 9.3e-170 opcA G Glucose-6-phosphate dehydrogenase subunit
HFCLIPBE_00916 1.8e-300 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFCLIPBE_00917 5.9e-122 3.2.2.9 F Phosphorylase superfamily
HFCLIPBE_00918 1e-73
HFCLIPBE_00920 1.2e-42 XAC3035 O Glutaredoxin
HFCLIPBE_00921 2.7e-112 E Binding-protein-dependent transport system inner membrane component
HFCLIPBE_00922 1.1e-118 tcyA ET Bacterial periplasmic substrate-binding proteins
HFCLIPBE_00923 1.5e-127 3.6.3.21 E ATPases associated with a variety of cellular activities
HFCLIPBE_00924 2.1e-303 pepD E Peptidase family C69
HFCLIPBE_00925 1.4e-196 XK27_01805 M Glycosyltransferase like family 2
HFCLIPBE_00926 9.2e-110 icaR K Bacterial regulatory proteins, tetR family
HFCLIPBE_00928 2.3e-155 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFCLIPBE_00929 4e-197 napA P Sodium/hydrogen exchanger family
HFCLIPBE_00930 4.9e-246 amt U Ammonium Transporter Family
HFCLIPBE_00931 4.9e-211 amt U Ammonium Transporter Family
HFCLIPBE_00932 1.3e-54 glnB K Nitrogen regulatory protein P-II
HFCLIPBE_00933 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HFCLIPBE_00936 2.1e-263 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HFCLIPBE_00937 9.2e-241 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HFCLIPBE_00938 1.5e-149 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HFCLIPBE_00939 2.9e-29 S granule-associated protein
HFCLIPBE_00940 7e-289 ubiB S ABC1 family
HFCLIPBE_00941 1.3e-185 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HFCLIPBE_00942 1.3e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFCLIPBE_00943 4.5e-87
HFCLIPBE_00944 1.5e-181 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HFCLIPBE_00946 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFCLIPBE_00947 8.4e-107 cpaE D bacterial-type flagellum organization
HFCLIPBE_00949 8.9e-175 cpaF U Type II IV secretion system protein
HFCLIPBE_00950 1.1e-66 U Type ii secretion system
HFCLIPBE_00951 1.6e-52 gspF NU Type II secretion system (T2SS), protein F
HFCLIPBE_00952 2.4e-28 S Protein of unknown function (DUF4244)
HFCLIPBE_00953 1e-35 U TadE-like protein
HFCLIPBE_00954 7.4e-12 S TIGRFAM helicase secretion neighborhood TadE-like protein
HFCLIPBE_00955 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HFCLIPBE_00956 4.2e-104 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFCLIPBE_00957 9.1e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HFCLIPBE_00958 7.7e-92 askB 1.1.1.3, 2.7.2.4 E ACT domain
HFCLIPBE_00959 2.4e-214 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFCLIPBE_00960 2.7e-188 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFCLIPBE_00961 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HFCLIPBE_00962 3.3e-62 ssb1 L Single-stranded DNA-binding protein
HFCLIPBE_00963 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFCLIPBE_00964 1.1e-69 rplI J Binds to the 23S rRNA
HFCLIPBE_00965 3.1e-92 pgdA 3.5.1.104 G Polysaccharide deacetylase
HFCLIPBE_00966 1.2e-156 3.6.1.27 I PAP2 superfamily
HFCLIPBE_00967 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFCLIPBE_00968 2.6e-92 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFCLIPBE_00969 1.4e-193 holB 2.7.7.7 L DNA polymerase III
HFCLIPBE_00970 1.3e-124 K helix_turn _helix lactose operon repressor
HFCLIPBE_00971 2.5e-32 ptsH G PTS HPr component phosphorylation site
HFCLIPBE_00972 7.8e-278 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFCLIPBE_00973 2.6e-103 S Phosphatidylethanolamine-binding protein
HFCLIPBE_00974 0.0 pepD E Peptidase family C69
HFCLIPBE_00975 2.9e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HFCLIPBE_00977 4.3e-167 pilT NU Type II/IV secretion system protein
HFCLIPBE_00978 1e-57 S Macrophage migration inhibitory factor (MIF)
HFCLIPBE_00979 2.3e-72 S GtrA-like protein
HFCLIPBE_00980 1.8e-201 EGP Major facilitator Superfamily
HFCLIPBE_00981 2.1e-104 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HFCLIPBE_00982 2.1e-51
HFCLIPBE_00983 1.3e-22 S Protein of unknown function (DUF805)
HFCLIPBE_00984 1.2e-294 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFCLIPBE_00987 2.4e-224 S Calcineurin-like phosphoesterase
HFCLIPBE_00988 1.2e-133 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HFCLIPBE_00989 1.3e-268 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HFCLIPBE_00990 1.1e-129 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HFCLIPBE_00991 1.7e-66 frataxin S Domain of unknown function (DU1801)
HFCLIPBE_00992 3.1e-199 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
HFCLIPBE_00993 6.3e-157 L Excalibur calcium-binding domain
HFCLIPBE_00994 3.7e-254 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFCLIPBE_00995 5.5e-301 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HFCLIPBE_00996 2.2e-161 S Sucrose-6F-phosphate phosphohydrolase
HFCLIPBE_00997 7.3e-175 plsC2 2.3.1.51 I Phosphate acyltransferases
HFCLIPBE_00998 1.6e-172 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HFCLIPBE_00999 1.2e-208 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HFCLIPBE_01001 1.9e-143 S CAAX protease self-immunity
HFCLIPBE_01002 6.4e-121 M Mechanosensitive ion channel
HFCLIPBE_01003 6.8e-190 CP_0417 3.1.1.3 S Protein of unknown function (DUF2974)
HFCLIPBE_01004 3e-100 K Bacterial regulatory proteins, tetR family
HFCLIPBE_01005 3.4e-178 M Cna protein B-type domain
HFCLIPBE_01006 0.0 amy 3.1.1.53, 3.2.1.1, 3.2.1.41 CBM48,GH13 G Alpha amylase, catalytic domain
HFCLIPBE_01007 1.3e-119 S Putative ABC-transporter type IV
HFCLIPBE_01008 6.5e-261 aspA 4.3.1.1 E Fumarase C C-terminus
HFCLIPBE_01009 1.1e-187 yxiO S Vacuole effluxer Atg22 like
HFCLIPBE_01010 1.4e-179 yegV G pfkB family carbohydrate kinase
HFCLIPBE_01011 4e-32 rpmB J Ribosomal L28 family
HFCLIPBE_01012 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
HFCLIPBE_01013 1e-94 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HFCLIPBE_01014 1.5e-101 XK27_02070 S Nitroreductase family
HFCLIPBE_01015 3.8e-149 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HFCLIPBE_01016 1.2e-103 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFCLIPBE_01017 1.4e-34 CP_0960 S Belongs to the UPF0109 family
HFCLIPBE_01018 4e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HFCLIPBE_01019 9.3e-152 S Endonuclease/Exonuclease/phosphatase family
HFCLIPBE_01020 6.4e-264 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFCLIPBE_01021 1.3e-280 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFCLIPBE_01022 4e-133 guaA1 6.3.5.2 F Peptidase C26
HFCLIPBE_01023 0.0 yjjK S ABC transporter
HFCLIPBE_01024 2.4e-90 ilvN 2.2.1.6 E ACT domain
HFCLIPBE_01025 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HFCLIPBE_01026 1.3e-137 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFCLIPBE_01027 3.4e-23 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HFCLIPBE_01028 4.6e-95 yceD S Uncharacterized ACR, COG1399
HFCLIPBE_01029 2e-37
HFCLIPBE_01030 2.6e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFCLIPBE_01031 1.1e-51 S Protein of unknown function (DUF3039)
HFCLIPBE_01032 2.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFCLIPBE_01033 3.2e-110
HFCLIPBE_01034 3.4e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HFCLIPBE_01035 8.2e-109 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFCLIPBE_01036 3.7e-153 S Auxin Efflux Carrier
HFCLIPBE_01040 1.6e-227 manC 2.7.7.13, 5.3.1.8 M Mannose-6-phosphate isomerase
HFCLIPBE_01041 0.0 pgi 5.3.1.9 G Belongs to the GPI family
HFCLIPBE_01042 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFCLIPBE_01043 2.6e-100 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HFCLIPBE_01044 3.9e-111 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFCLIPBE_01045 5.3e-177 K helix_turn _helix lactose operon repressor
HFCLIPBE_01046 0.0 cydD V ABC transporter transmembrane region
HFCLIPBE_01047 1.1e-278 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
HFCLIPBE_01048 1.4e-113 S Enoyl-(Acyl carrier protein) reductase
HFCLIPBE_01049 4.2e-258 2.6.1.55 E Aminotransferase class-III
HFCLIPBE_01050 2.6e-205 EK Bacterial regulatory proteins, gntR family
HFCLIPBE_01051 5.4e-187 natB E Receptor family ligand binding region
HFCLIPBE_01052 1.7e-33 D nuclear chromosome segregation
HFCLIPBE_01054 7.5e-90 L Protein of unknown function (DUF1524)
HFCLIPBE_01056 9e-198 mntH P H( )-stimulated, divalent metal cation uptake system
HFCLIPBE_01057 1.6e-244 EGP Major facilitator Superfamily
HFCLIPBE_01058 1.2e-196 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HFCLIPBE_01059 8.9e-78 3.1.3.48 T Low molecular weight phosphatase family
HFCLIPBE_01060 1.2e-205 S Endonuclease/Exonuclease/phosphatase family
HFCLIPBE_01061 0.0 amyE 3.2.1.1, 3.2.1.80 GH13 G Belongs to the glycosyl hydrolase 13 family
HFCLIPBE_01062 8.2e-32 G Acyltransferase family
HFCLIPBE_01064 7.3e-60 GT2 S Glycosyl transferase family 2
HFCLIPBE_01066 6.6e-40 GT2 S Glycosyl transferase family 2
HFCLIPBE_01067 5e-38 cps1D M Domain of unknown function (DUF4422)
HFCLIPBE_01068 1.9e-62 tuaB S Polysaccharide biosynthesis protein
HFCLIPBE_01069 4e-95 K Transcriptional regulator
HFCLIPBE_01070 4.6e-66 S Glutamine amidotransferase domain
HFCLIPBE_01071 4e-155 glnA3 6.3.1.2 E glutamine synthetase
HFCLIPBE_01072 4.3e-157 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFCLIPBE_01073 1.7e-139 S metal-dependent hydrolase of the TIM-barrel fold
HFCLIPBE_01074 1.6e-218 E amino acid
HFCLIPBE_01075 2.3e-131 S AAA domain, putative AbiEii toxin, Type IV TA system
HFCLIPBE_01076 1.2e-36 S RloB-like protein
HFCLIPBE_01077 1.4e-200 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFCLIPBE_01078 2.9e-268 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFCLIPBE_01079 1e-149 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFCLIPBE_01080 2.2e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFCLIPBE_01081 3e-58 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HFCLIPBE_01082 3.9e-201
HFCLIPBE_01083 5.6e-60 2.3.2.3, 3.2.1.4 GH5,GH9 M PFAM glycoside hydrolase, family 10
HFCLIPBE_01084 6.3e-53 M Esterase
HFCLIPBE_01086 5.2e-130 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HFCLIPBE_01087 6.9e-146 rfbJ M Glycosyl transferase family 2
HFCLIPBE_01088 1.1e-55
HFCLIPBE_01089 3.8e-121
HFCLIPBE_01090 1.4e-200 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFCLIPBE_01091 1.3e-260 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFCLIPBE_01092 3.9e-102 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFCLIPBE_01093 2.3e-149 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFCLIPBE_01094 5.6e-19 D nuclear chromosome segregation
HFCLIPBE_01096 4.6e-18 M Psort location Cellwall, score
HFCLIPBE_01097 7.1e-31 3.4.22.70 M Sortase family
HFCLIPBE_01103 3.9e-52
HFCLIPBE_01105 4e-31 2.7.11.1 S HipA-like C-terminal domain
HFCLIPBE_01106 3.7e-59 L Transposase IS200 like
HFCLIPBE_01107 1.9e-138 L Helix-turn-helix domain
HFCLIPBE_01108 6.4e-62 2.7.11.1 S HipA-like C-terminal domain
HFCLIPBE_01110 1e-47
HFCLIPBE_01113 1.8e-72 NU Tfp pilus assembly protein FimV
HFCLIPBE_01116 3.6e-10 D nuclear chromosome segregation
HFCLIPBE_01117 5.1e-105 rgpC U Transport permease protein
HFCLIPBE_01118 2.6e-132 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
HFCLIPBE_01119 2.2e-266 rgpF M Rhamnan synthesis protein F
HFCLIPBE_01120 2.4e-131 M Glycosyltransferase like family 2
HFCLIPBE_01121 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HFCLIPBE_01122 5e-33
HFCLIPBE_01123 4.3e-189 wcoI DM Psort location CytoplasmicMembrane, score
HFCLIPBE_01124 5.6e-82
HFCLIPBE_01125 1.2e-59 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HFCLIPBE_01127 9.9e-167 S G5
HFCLIPBE_01128 1.7e-49 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HFCLIPBE_01129 2.4e-112 F Domain of unknown function (DUF4916)
HFCLIPBE_01130 5e-124 mhpC I Alpha/beta hydrolase family
HFCLIPBE_01131 1.5e-179 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HFCLIPBE_01132 1e-235 enhA_2 S L,D-transpeptidase catalytic domain
HFCLIPBE_01133 4.7e-65 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HFCLIPBE_01134 2e-211 S Uncharacterized conserved protein (DUF2183)
HFCLIPBE_01135 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HFCLIPBE_01136 1.2e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HFCLIPBE_01137 5.9e-30 J TM2 domain
HFCLIPBE_01138 9.4e-142 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HFCLIPBE_01139 1.5e-127 glxR K helix_turn_helix, cAMP Regulatory protein
HFCLIPBE_01140 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HFCLIPBE_01141 1.7e-202 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
HFCLIPBE_01142 0.0 E Transglutaminase-like superfamily
HFCLIPBE_01143 8.6e-173 S Protein of unknown function DUF58
HFCLIPBE_01144 2.3e-167 S ATPase family associated with various cellular activities (AAA)
HFCLIPBE_01145 0.0 S Fibronectin type 3 domain
HFCLIPBE_01146 9.9e-161 KLT Protein tyrosine kinase
HFCLIPBE_01148 3.1e-217 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HFCLIPBE_01149 3.6e-121 ppm1 2.4.1.83 GT2 S Glycosyl transferase family 2
HFCLIPBE_01150 1.3e-132 glpR K DeoR C terminal sensor domain
HFCLIPBE_01151 1.1e-247 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HFCLIPBE_01152 7.6e-212 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HFCLIPBE_01153 2.5e-40 gcvR T Belongs to the UPF0237 family
HFCLIPBE_01154 1.5e-237 S UPF0210 protein
HFCLIPBE_01155 1.9e-145
HFCLIPBE_01156 1.9e-16
HFCLIPBE_01157 0.0 M Protein of unknown function (DUF3289)
HFCLIPBE_01158 2.5e-82
HFCLIPBE_01159 7.6e-114 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFCLIPBE_01160 1.8e-129 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HFCLIPBE_01161 4.7e-72
HFCLIPBE_01163 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFCLIPBE_01164 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFCLIPBE_01165 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HFCLIPBE_01166 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HFCLIPBE_01167 2.3e-133 K -acetyltransferase
HFCLIPBE_01168 9e-216 G Major Facilitator Superfamily
HFCLIPBE_01169 1.9e-125 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFCLIPBE_01170 1.2e-163 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFCLIPBE_01171 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFCLIPBE_01172 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
HFCLIPBE_01173 3.8e-88 S Nucleotidyltransferase domain
HFCLIPBE_01174 1.1e-59 S Protein of unknown function DUF86
HFCLIPBE_01175 5.9e-263 gabT 2.6.1.19, 2.6.1.22 E Aminotransferase class-III
HFCLIPBE_01176 0.0 1.1.1.1, 1.1.1.202 CE Amino acid permease
HFCLIPBE_01177 1.7e-105 mmyX 5.3.1.12 F Cytidylate kinase-like family
HFCLIPBE_01178 8.7e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFCLIPBE_01179 3.4e-107 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFCLIPBE_01180 1.7e-148 S zinc finger
HFCLIPBE_01181 9.9e-155 S Endonuclease/Exonuclease/phosphatase family
HFCLIPBE_01182 4.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFCLIPBE_01183 1.1e-216 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFCLIPBE_01184 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HFCLIPBE_01185 1.1e-135 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFCLIPBE_01186 1.5e-17 yfeO P Chloride transporter, ClC family
HFCLIPBE_01187 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HFCLIPBE_01188 6.2e-243 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
HFCLIPBE_01189 5.1e-117 K Bacterial regulatory proteins, tetR family
HFCLIPBE_01190 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
HFCLIPBE_01191 3.6e-96 K MarR family
HFCLIPBE_01192 0.0 V ABC transporter, ATP-binding protein
HFCLIPBE_01193 0.0 V ABC transporter transmembrane region
HFCLIPBE_01194 0.0 U Spy0128-like isopeptide containing domain
HFCLIPBE_01195 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFCLIPBE_01196 0.0 tetP J Elongation factor G, domain IV
HFCLIPBE_01197 2.4e-57 yccF S Inner membrane component domain
HFCLIPBE_01199 1.2e-180 yghZ C Aldo/keto reductase family
HFCLIPBE_01200 3.8e-185 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HFCLIPBE_01201 1.6e-227 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HFCLIPBE_01202 1.7e-135 yxeN P Binding-protein-dependent transport system inner membrane component
HFCLIPBE_01203 1.7e-148 tcyN 3.6.3.21 E ATPases associated with a variety of cellular activities
HFCLIPBE_01204 1.4e-103 K Acetyltransferase (GNAT) domain
HFCLIPBE_01205 7e-236 1.8.5.7 O Glutathione S-transferase
HFCLIPBE_01206 3.8e-35 ET Bacterial periplasmic substrate-binding proteins
HFCLIPBE_01207 6.7e-81 ET Bacterial periplasmic substrate-binding proteins
HFCLIPBE_01208 4e-127 ET Bacterial periplasmic substrate-binding proteins
HFCLIPBE_01209 9.4e-214 1.8.5.7 O Glutathione S-transferase
HFCLIPBE_01210 8.6e-211 S Peptidase dimerisation domain
HFCLIPBE_01211 1.5e-237 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
HFCLIPBE_01212 2e-147 mdh 1.1.1.350 C Malate/L-lactate dehydrogenase
HFCLIPBE_01213 1.5e-119 XK27_08050 O prohibitin homologues
HFCLIPBE_01214 1.8e-148 S Patatin-like phospholipase
HFCLIPBE_01215 4.4e-130 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HFCLIPBE_01217 6.4e-33
HFCLIPBE_01218 3.5e-148 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HFCLIPBE_01219 2.2e-106 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
HFCLIPBE_01220 4.2e-33 S Protein of unknown function (DUF3107)
HFCLIPBE_01221 4.4e-188 mphA S Aminoglycoside phosphotransferase
HFCLIPBE_01224 3.7e-242 uvrD2 3.6.4.12 L DNA helicase
HFCLIPBE_01225 1.5e-215 S Zincin-like metallopeptidase
HFCLIPBE_01226 1.4e-113 lon T Belongs to the peptidase S16 family
HFCLIPBE_01227 4.2e-74 S Protein of unknown function (DUF3052)
HFCLIPBE_01229 5.9e-125 2.7.11.1 NU Tfp pilus assembly protein FimV
HFCLIPBE_01230 8.9e-207 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HFCLIPBE_01231 1.5e-212 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HFCLIPBE_01232 1.2e-279 I acetylesterase activity
HFCLIPBE_01233 1.1e-119 recO L Involved in DNA repair and RecF pathway recombination
HFCLIPBE_01234 1.5e-149 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFCLIPBE_01235 1.6e-171 K helix_turn _helix lactose operon repressor
HFCLIPBE_01236 4.1e-255 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HFCLIPBE_01237 6.9e-232 lacY P LacY proton/sugar symporter
HFCLIPBE_01238 1.1e-149 K helix_turn _helix lactose operon repressor
HFCLIPBE_01239 6.2e-61 S Thiamine-binding protein
HFCLIPBE_01240 2.4e-129 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFCLIPBE_01241 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HFCLIPBE_01242 5.7e-111 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFCLIPBE_01243 4.9e-129 S enterobacterial common antigen metabolic process
HFCLIPBE_01244 1.5e-149
HFCLIPBE_01245 2.5e-126 pilT NU Type II/IV secretion system protein
HFCLIPBE_01246 5.6e-99 pilT NU Type II/IV secretion system protein
HFCLIPBE_01247 1.1e-08 pilT NU Type II/IV secretion system protein
HFCLIPBE_01249 2.8e-249 pulE NU Type II/IV secretion system protein
HFCLIPBE_01250 5e-28 pilA NU general secretion pathway protein
HFCLIPBE_01251 9.7e-37 ppdC NU Prokaryotic N-terminal methylation motif
HFCLIPBE_01252 2.3e-25 S Prokaryotic N-terminal methylation motif
HFCLIPBE_01253 2.1e-150 pilC U Type II secretion system (T2SS), protein F
HFCLIPBE_01254 5.4e-68
HFCLIPBE_01255 4.9e-101 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HFCLIPBE_01256 1.8e-110 pilM NU Type IV pilus assembly protein PilM;
HFCLIPBE_01257 1.2e-57 pilN NU PFAM Fimbrial assembly family protein
HFCLIPBE_01258 6.5e-39 mshJ NU Type II secretion system (T2SS), protein M
HFCLIPBE_01259 2.7e-301 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HFCLIPBE_01260 2.4e-239 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFCLIPBE_01261 5.4e-165 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFCLIPBE_01262 1.4e-49 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFCLIPBE_01263 3.7e-26 yggT S YGGT family
HFCLIPBE_01264 1.1e-75 GT2,GT4 D DivIVA protein
HFCLIPBE_01265 4.8e-59 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFCLIPBE_01266 3.4e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HFCLIPBE_01267 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HFCLIPBE_01268 2.8e-252 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFCLIPBE_01269 9.9e-219 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFCLIPBE_01270 5.6e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HFCLIPBE_01271 1.3e-71
HFCLIPBE_01272 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFCLIPBE_01273 2.8e-126 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HFCLIPBE_01274 7.5e-263 glnA2 6.3.1.2 E glutamine synthetase
HFCLIPBE_01275 9.5e-151 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HFCLIPBE_01276 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HFCLIPBE_01277 1.6e-103 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HFCLIPBE_01278 9.1e-244 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFCLIPBE_01279 1.1e-175 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HFCLIPBE_01280 7.1e-141 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFCLIPBE_01281 4.9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFCLIPBE_01282 5.2e-23 M Lysin motif
HFCLIPBE_01283 4e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFCLIPBE_01284 1.5e-217 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HFCLIPBE_01285 0.0 L DNA helicase
HFCLIPBE_01286 2.9e-72 mraZ K Belongs to the MraZ family
HFCLIPBE_01287 4.7e-165 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFCLIPBE_01288 1.5e-45 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HFCLIPBE_01289 3e-267 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HFCLIPBE_01290 7.6e-115 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFCLIPBE_01291 1.6e-205 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFCLIPBE_01292 1.2e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFCLIPBE_01293 4.1e-217 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFCLIPBE_01294 2.7e-147 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HFCLIPBE_01295 2e-195 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFCLIPBE_01296 3.3e-270 murC 6.3.2.8 M Belongs to the MurCDEF family
HFCLIPBE_01297 4.2e-126 ftsQ 6.3.2.4 D Cell division protein FtsQ
HFCLIPBE_01298 5.8e-120 polC_1 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HFCLIPBE_01299 5.1e-242 V MatE
HFCLIPBE_01300 7.7e-94 K Helix-turn-helix domain protein
HFCLIPBE_01302 4.7e-32
HFCLIPBE_01303 4.8e-44 V Abi-like protein
HFCLIPBE_01304 1.5e-177 S Protein of unknown function DUF262
HFCLIPBE_01305 4.7e-14
HFCLIPBE_01306 7.1e-36
HFCLIPBE_01307 6.8e-81 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFCLIPBE_01308 5.2e-144 tnp3512a L Transposase
HFCLIPBE_01310 1.3e-19 K Transcriptional regulator
HFCLIPBE_01312 3.9e-22 S SMI1 / KNR4 family (SUKH-1)
HFCLIPBE_01314 1.3e-60 3.1.21.3 V Type I restriction modification DNA specificity domain protein
HFCLIPBE_01315 2e-113 L Phage integrase family
HFCLIPBE_01316 9.7e-81 3.1.21.3 V type I restriction enzyme, S subunit K01154
HFCLIPBE_01317 3.1e-67 V Restriction endonuclease
HFCLIPBE_01318 8.7e-227 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
HFCLIPBE_01319 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HFCLIPBE_01320 3.7e-29 S AraC-like ligand binding domain
HFCLIPBE_01321 2.5e-76 Q Methyltransferase domain protein
HFCLIPBE_01322 9.2e-157 3.2.1.4 GH5,GH9 G CBD_II
HFCLIPBE_01324 2.9e-213 G Major Facilitator Superfamily
HFCLIPBE_01325 5.6e-169 2.7.1.4 G pfkB family carbohydrate kinase
HFCLIPBE_01326 6.1e-203 GK ROK family
HFCLIPBE_01327 1.9e-53 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HFCLIPBE_01328 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HFCLIPBE_01330 2.3e-87 3.6.1.55 F NUDIX domain
HFCLIPBE_01331 1e-277 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
HFCLIPBE_01332 0.0 smc D Required for chromosome condensation and partitioning
HFCLIPBE_01333 7.3e-236 6.3.1.12 S ATP-grasp
HFCLIPBE_01334 1.7e-259 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFCLIPBE_01335 2.2e-129 dnaQ2 2.7.7.7 L Exonuclease
HFCLIPBE_01336 4e-103 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HFCLIPBE_01337 2.4e-50
HFCLIPBE_01338 5.3e-162 galM 5.1.3.3 G Aldose 1-epimerase
HFCLIPBE_01339 3.6e-168 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HFCLIPBE_01340 6e-91 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFCLIPBE_01341 9.4e-200 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFCLIPBE_01342 2.6e-114 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HFCLIPBE_01343 1.1e-98 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFCLIPBE_01344 1.3e-25 rpmI J Ribosomal protein L35
HFCLIPBE_01345 9e-60 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFCLIPBE_01346 1.1e-143 xerD D recombinase XerD
HFCLIPBE_01347 1.4e-147 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HFCLIPBE_01348 1.2e-91 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFCLIPBE_01349 5.2e-66 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFCLIPBE_01350 0.0 typA T Elongation factor G C-terminus
HFCLIPBE_01351 1.1e-68
HFCLIPBE_01352 1.4e-158 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HFCLIPBE_01353 7.3e-152 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HFCLIPBE_01354 9.2e-28
HFCLIPBE_01355 3.5e-122 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HFCLIPBE_01357 7.5e-297 E ABC transporter, substrate-binding protein, family 5
HFCLIPBE_01358 3.2e-151 dppB EP Binding-protein-dependent transport system inner membrane component
HFCLIPBE_01359 4.6e-169 dppC EP N-terminal TM domain of oligopeptide transport permease C
HFCLIPBE_01360 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
HFCLIPBE_01361 5.2e-164 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HFCLIPBE_01362 7e-114 S Protein of unknown function (DUF3710)
HFCLIPBE_01363 1.3e-115 S Protein of unknown function (DUF3159)
HFCLIPBE_01364 3.4e-228 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFCLIPBE_01365 6.5e-104 gatC 2.3.1.128 J Acetyltransferase (GNAT) domain
HFCLIPBE_01366 3.1e-38 S Psort location CytoplasmicMembrane, score
HFCLIPBE_01367 3e-33 pilA NU Prokaryotic N-terminal methylation motif
HFCLIPBE_01368 3.8e-28 K Bacterial regulatory proteins, tetR family
HFCLIPBE_01369 2.1e-11 I Carboxylesterase family
HFCLIPBE_01370 2.1e-53 K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HFCLIPBE_01371 4.1e-150 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
HFCLIPBE_01372 1.4e-73
HFCLIPBE_01373 4.7e-156 MA20_14895 S Conserved hypothetical protein 698
HFCLIPBE_01374 0.0 4.2.1.53 S MCRA family
HFCLIPBE_01375 3.4e-139 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
HFCLIPBE_01376 0.0 ctpE P E1-E2 ATPase
HFCLIPBE_01377 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HFCLIPBE_01378 3.6e-299 S Protein of unknown function DUF262
HFCLIPBE_01379 3.7e-54
HFCLIPBE_01380 3.7e-109 ybhL S Belongs to the BI1 family
HFCLIPBE_01381 3.7e-134 ydeD EG EamA-like transporter family
HFCLIPBE_01382 6.8e-274 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 3.5.99.2 H Phosphomethylpyrimidine kinase
HFCLIPBE_01383 2.4e-108 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HFCLIPBE_01384 6.9e-270 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HFCLIPBE_01385 4.6e-178 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFCLIPBE_01386 0.0 ftsK D FtsK SpoIIIE family protein
HFCLIPBE_01387 3.1e-105 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFCLIPBE_01388 6.2e-70 cinA 3.5.1.42 S Belongs to the CinA family
HFCLIPBE_01389 1.4e-68 K Helix-turn-helix XRE-family like proteins
HFCLIPBE_01390 4.8e-38 S Protein of unknown function (DUF3046)
HFCLIPBE_01391 4.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFCLIPBE_01392 4.1e-69 recX S Modulates RecA activity
HFCLIPBE_01394 4.7e-104 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFCLIPBE_01395 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFCLIPBE_01396 2.1e-183 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFCLIPBE_01397 1.2e-44
HFCLIPBE_01398 2.6e-121 plsC2 2.3.1.51 I Phosphate acyltransferases
HFCLIPBE_01399 6.5e-299 pknL 2.7.11.1 KLT PASTA
HFCLIPBE_01400 4.7e-138 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
HFCLIPBE_01401 4e-95
HFCLIPBE_01402 3.4e-179 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFCLIPBE_01403 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HFCLIPBE_01404 1.5e-214 2.4.1.345 GT4 M Glycosyl transferase 4-like domain
HFCLIPBE_01405 7.3e-257 ftsZ M Domain of unknown function (DUF4173)
HFCLIPBE_01406 7e-62 S Protein of unknown function (DUF2975)
HFCLIPBE_01407 8.1e-35 yozG K Cro/C1-type HTH DNA-binding domain
HFCLIPBE_01408 4.9e-221 G Major Facilitator Superfamily
HFCLIPBE_01409 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HFCLIPBE_01410 6.8e-186 S Type I phosphodiesterase / nucleotide pyrophosphatase
HFCLIPBE_01411 2.1e-115 S Protein of unknown function (DUF3071)
HFCLIPBE_01412 4e-44 S Domain of unknown function (DUF4193)
HFCLIPBE_01413 1.3e-76 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HFCLIPBE_01414 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFCLIPBE_01415 4.6e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFCLIPBE_01416 1.9e-155 S Sucrose-6F-phosphate phosphohydrolase
HFCLIPBE_01417 9.5e-162 metQ P NLPA lipoprotein
HFCLIPBE_01418 1.8e-201 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFCLIPBE_01419 5.1e-117 metI P Binding-protein-dependent transport system inner membrane component
HFCLIPBE_01420 6.4e-218 S Peptidase dimerisation domain
HFCLIPBE_01421 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HFCLIPBE_01422 1.1e-29
HFCLIPBE_01423 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HFCLIPBE_01424 2.7e-166 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFCLIPBE_01425 5.1e-57 S Protein of unknown function (DUF3000)
HFCLIPBE_01426 1.2e-215 rnd 3.1.13.5 J 3'-5' exonuclease
HFCLIPBE_01427 1.1e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFCLIPBE_01428 7.4e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFCLIPBE_01429 4.4e-118 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFCLIPBE_01430 2.8e-213 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFCLIPBE_01432 5.8e-216 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HFCLIPBE_01433 3.4e-124 fmt2 3.2.2.10 S Belongs to the LOG family
HFCLIPBE_01434 1.1e-65 safC S O-methyltransferase
HFCLIPBE_01435 5.2e-133 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
HFCLIPBE_01436 3.2e-299 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HFCLIPBE_01437 1.7e-49 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HFCLIPBE_01438 1.3e-157 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HFCLIPBE_01439 8.1e-237 comM O Magnesium chelatase, subunit ChlI C-terminal
HFCLIPBE_01440 1.9e-52 yraN L Belongs to the UPF0102 family
HFCLIPBE_01441 1.8e-159 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HFCLIPBE_01442 1.7e-251 metY 2.5.1.49 E Aminotransferase class-V
HFCLIPBE_01443 2.1e-286 E ABC transporter, substrate-binding protein, family 5
HFCLIPBE_01444 2.2e-88 XK27_01265 S ECF-type riboflavin transporter, S component
HFCLIPBE_01445 2.2e-205 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
HFCLIPBE_01446 6.1e-90 P Cobalt transport protein
HFCLIPBE_01448 6.6e-137 V ABC transporter, ATP-binding protein
HFCLIPBE_01449 0.0 MV MacB-like periplasmic core domain
HFCLIPBE_01450 6.9e-120 K helix_turn_helix, Lux Regulon
HFCLIPBE_01451 5e-280 S Predicted membrane protein (DUF2207)
HFCLIPBE_01452 0.0 tcsS2 T Histidine kinase
HFCLIPBE_01453 1.2e-263 pip 3.4.11.5 S alpha/beta hydrolase fold
HFCLIPBE_01454 1e-142 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFCLIPBE_01455 8.2e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFCLIPBE_01457 2.5e-95 M L,D-transpeptidase catalytic domain
HFCLIPBE_01458 3.1e-158 3.1.3.73 G Phosphoglycerate mutase family
HFCLIPBE_01459 1.9e-223 rutG F Permease family
HFCLIPBE_01460 2.7e-131 ybbM V Uncharacterised protein family (UPF0014)
HFCLIPBE_01461 2.8e-137 ybbL V ATPases associated with a variety of cellular activities
HFCLIPBE_01462 0.0 S Uncharacterised protein family (UPF0182)
HFCLIPBE_01463 7.8e-114 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HFCLIPBE_01464 1.8e-108 yijF S Domain of unknown function (DUF1287)
HFCLIPBE_01465 8.6e-172 P NMT1/THI5 like
HFCLIPBE_01466 4e-166 iunH1 3.2.2.1 F nucleoside hydrolase
HFCLIPBE_01467 3.1e-82 2.3.1.183 M Acetyltransferase (GNAT) domain
HFCLIPBE_01468 3.5e-111 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFCLIPBE_01469 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFCLIPBE_01470 1e-126 3.2.1.8 S alpha beta
HFCLIPBE_01471 5.1e-07
HFCLIPBE_01472 1.6e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFCLIPBE_01473 1.7e-57 divIC D Septum formation initiator
HFCLIPBE_01474 1.4e-94 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HFCLIPBE_01475 1.3e-174 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HFCLIPBE_01477 2.5e-22
HFCLIPBE_01479 1.3e-08
HFCLIPBE_01481 4.9e-40 2.7.11.1 S RDD family
HFCLIPBE_01482 2.2e-70
HFCLIPBE_01483 5e-255 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HFCLIPBE_01484 2.2e-64 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HFCLIPBE_01485 1.3e-76 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFCLIPBE_01486 1.2e-123 yplQ S Haemolysin-III related
HFCLIPBE_01487 4.8e-234 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HFCLIPBE_01488 6.4e-47 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HFCLIPBE_01489 3.4e-119 D FtsK/SpoIIIE family
HFCLIPBE_01490 2.4e-165 K Cell envelope-related transcriptional attenuator domain
HFCLIPBE_01491 6.4e-196 K Cell envelope-related transcriptional attenuator domain
HFCLIPBE_01492 9.4e-39 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HFCLIPBE_01493 0.0 S Glycosyl transferase, family 2
HFCLIPBE_01494 3.7e-160
HFCLIPBE_01495 1.8e-57 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HFCLIPBE_01496 1.1e-128 cof 5.2.1.8 T Eukaryotic phosphomannomutase
HFCLIPBE_01497 1.7e-44 ctsW S Phosphoribosyl transferase domain
HFCLIPBE_01498 9.7e-178 2.7.7.7 L Domain of unknown function (DUF4113)
HFCLIPBE_01499 4.9e-71 rulA 3.4.21.88 KT Peptidase S24-like
HFCLIPBE_01500 2.5e-182 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HFCLIPBE_01501 8.4e-126 T Response regulator receiver domain protein
HFCLIPBE_01502 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HFCLIPBE_01503 5.9e-98 carD K CarD-like/TRCF domain
HFCLIPBE_01504 1.2e-60 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HFCLIPBE_01505 9.3e-126 znuB U ABC 3 transport family
HFCLIPBE_01506 4.6e-129 znuC P ATPases associated with a variety of cellular activities
HFCLIPBE_01507 3.4e-112 P Zinc-uptake complex component A periplasmic
HFCLIPBE_01508 7.7e-147 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFCLIPBE_01509 1.7e-239 rpsA J Ribosomal protein S1
HFCLIPBE_01510 9.7e-67 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFCLIPBE_01511 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFCLIPBE_01512 1.3e-166 terC P Integral membrane protein, TerC family
HFCLIPBE_01513 1.6e-271 pyk 2.7.1.40 G Pyruvate kinase
HFCLIPBE_01514 1.1e-110 aspA 3.6.1.13 L NUDIX domain
HFCLIPBE_01515 2.9e-149 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFCLIPBE_01516 3.3e-116 U Binding-protein-dependent transport system inner membrane component
HFCLIPBE_01517 1.4e-125 U Binding-protein-dependent transport system inner membrane component
HFCLIPBE_01518 7.6e-171 P Bacterial extracellular solute-binding protein
HFCLIPBE_01520 8.3e-116 pdtaR T Response regulator receiver domain protein
HFCLIPBE_01521 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFCLIPBE_01522 3.4e-142 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HFCLIPBE_01523 6.6e-93 3.6.1.13 L NUDIX domain
HFCLIPBE_01524 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HFCLIPBE_01525 2.2e-201 ykiI
HFCLIPBE_01528 8.2e-260 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HFCLIPBE_01530 4.4e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFCLIPBE_01531 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HFCLIPBE_01532 6.7e-178 V Abi-like protein
HFCLIPBE_01533 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HFCLIPBE_01534 1.4e-300 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HFCLIPBE_01535 5.9e-188 3.5.1.4, 6.3.5.6, 6.3.5.7 J Protein of unknown function (DUF3225)
HFCLIPBE_01536 2e-158 S beta-lactamase activity
HFCLIPBE_01537 1.4e-08 L Excalibur calcium-binding domain
HFCLIPBE_01538 3.7e-125 L Uncharacterized conserved protein (DUF2075)
HFCLIPBE_01539 5.2e-173 S Protein of unknown function DUF262
HFCLIPBE_01541 3.2e-202
HFCLIPBE_01542 8.5e-286 S ATPases associated with a variety of cellular activities
HFCLIPBE_01543 3.3e-259 EGP Major facilitator Superfamily
HFCLIPBE_01544 6e-29 feoA P iron ion homeostasis
HFCLIPBE_01545 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HFCLIPBE_01546 7.3e-11
HFCLIPBE_01547 5.5e-132 S Putative ABC-transporter type IV
HFCLIPBE_01548 3e-106 mpg 3.2.2.21 L Methylpurine-DNA glycosylase (MPG)
HFCLIPBE_01549 2e-177 V ATPases associated with a variety of cellular activities
HFCLIPBE_01550 1.7e-200 V ABC-2 family transporter protein
HFCLIPBE_01551 5.8e-204 V ABC-2 family transporter protein
HFCLIPBE_01552 4.2e-90 K acetyltransferase
HFCLIPBE_01553 5.8e-65 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFCLIPBE_01554 7.9e-144 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HFCLIPBE_01555 0.0 S TerB-C domain
HFCLIPBE_01556 1.6e-271 P P-loop Domain of unknown function (DUF2791)
HFCLIPBE_01557 0.0 lhr L DEAD DEAH box helicase
HFCLIPBE_01558 1.7e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HFCLIPBE_01559 5.9e-235 pbuX F Permease family
HFCLIPBE_01560 4.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFCLIPBE_01561 0.0 pcrA 3.6.4.12 L DNA helicase
HFCLIPBE_01562 1.6e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFCLIPBE_01563 5.6e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HFCLIPBE_01564 6.6e-134 oatA I Psort location CytoplasmicMembrane, score 9.99
HFCLIPBE_01565 4.5e-102 pgm3 G Phosphoglycerate mutase family
HFCLIPBE_01566 2.5e-50 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HFCLIPBE_01567 1.3e-29
HFCLIPBE_01568 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFCLIPBE_01569 1.3e-58 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFCLIPBE_01570 1.6e-171 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFCLIPBE_01571 8.6e-210 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HFCLIPBE_01572 9e-277 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HFCLIPBE_01573 6.2e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HFCLIPBE_01574 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
HFCLIPBE_01575 1.2e-285 amy 3.2.1.1, 3.2.1.41 CBM48,GH13 G Aamy_C
HFCLIPBE_01576 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFCLIPBE_01577 2.7e-285 sufB O FeS assembly protein SufB
HFCLIPBE_01578 2.5e-215 sufD O FeS assembly protein SufD
HFCLIPBE_01579 1.3e-142 sufC O FeS assembly ATPase SufC
HFCLIPBE_01580 8.9e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFCLIPBE_01581 1.9e-101 iscU C SUF system FeS assembly protein, NifU family
HFCLIPBE_01582 2.4e-94 yitW S Iron-sulfur cluster assembly protein
HFCLIPBE_01583 4.7e-149 spoU 2.1.1.185 J SpoU rRNA Methylase family
HFCLIPBE_01584 4.8e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFCLIPBE_01586 1.4e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HFCLIPBE_01587 3.7e-179 phoH T PhoH-like protein
HFCLIPBE_01588 2.8e-86 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFCLIPBE_01589 6e-221 corC S CBS domain
HFCLIPBE_01590 1.4e-165 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFCLIPBE_01591 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HFCLIPBE_01592 1.5e-163 pntAA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HFCLIPBE_01593 9.5e-42 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HFCLIPBE_01594 4.1e-235 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HFCLIPBE_01595 1.6e-119 S alpha beta
HFCLIPBE_01596 2.6e-91 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HFCLIPBE_01597 5.8e-224 ilvE 2.6.1.42 E Amino-transferase class IV
HFCLIPBE_01598 1.1e-101 S UPF0126 domain
HFCLIPBE_01599 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
HFCLIPBE_01600 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFCLIPBE_01601 4.3e-250 hemN H Involved in the biosynthesis of porphyrin-containing compound
HFCLIPBE_01602 8.9e-113 magIII L endonuclease III
HFCLIPBE_01603 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HFCLIPBE_01604 5.9e-156 yebE S DUF218 domain
HFCLIPBE_01605 4.8e-139 pcaC 4.1.1.44 S Cupin domain
HFCLIPBE_01606 7.3e-83 C Flavodoxin
HFCLIPBE_01607 1.4e-105 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HFCLIPBE_01608 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HFCLIPBE_01609 6.8e-292 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HFCLIPBE_01610 1.4e-59
HFCLIPBE_01611 2.7e-37 M Peptidase family M23
HFCLIPBE_01612 4e-148 G ABC transporter substrate-binding protein
HFCLIPBE_01613 6.3e-232 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HFCLIPBE_01614 3.8e-183 guaB 1.1.1.205 F IMP dehydrogenase family protein
HFCLIPBE_01616 7.9e-14
HFCLIPBE_01617 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
HFCLIPBE_01618 6.4e-79 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFCLIPBE_01619 3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HFCLIPBE_01620 4.2e-145 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFCLIPBE_01621 3.3e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HFCLIPBE_01622 5.4e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFCLIPBE_01623 3.3e-146 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
HFCLIPBE_01624 2.4e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HFCLIPBE_01625 8.5e-134 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HFCLIPBE_01626 7.9e-65 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HFCLIPBE_01627 1.8e-279 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFCLIPBE_01628 0.0 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HFCLIPBE_01629 9.9e-147 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HFCLIPBE_01630 1.8e-159 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFCLIPBE_01631 5.2e-96 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
HFCLIPBE_01632 3.2e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HFCLIPBE_01633 2.2e-151 hisG 2.4.2.17 F ATP phosphoribosyltransferase
HFCLIPBE_01634 2e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFCLIPBE_01635 4.6e-134 S Bacterial protein of unknown function (DUF881)
HFCLIPBE_01636 8.1e-33 sbp S Protein of unknown function (DUF1290)
HFCLIPBE_01637 1.4e-110 S Bacterial protein of unknown function (DUF881)
HFCLIPBE_01638 5.8e-71 garA T Inner membrane component of T3SS, cytoplasmic domain
HFCLIPBE_01639 4.3e-81 K helix_turn_helix, mercury resistance
HFCLIPBE_01642 4.3e-85 S Thiamine-binding protein
HFCLIPBE_01645 2e-09
HFCLIPBE_01653 3.1e-117 pgp 3.1.3.18 S HAD-hyrolase-like
HFCLIPBE_01654 2.4e-59 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HFCLIPBE_01655 0.0 helY L DEAD DEAH box helicase
HFCLIPBE_01656 6.6e-16
HFCLIPBE_01657 0.0 pafB K WYL domain
HFCLIPBE_01658 5.8e-234 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HFCLIPBE_01659 3.9e-18 S VRR_NUC
HFCLIPBE_01662 1.4e-59
HFCLIPBE_01666 6.6e-152 3.1.21.4 L XamI restriction endonuclease
HFCLIPBE_01667 3.2e-214 xamIM L N-6 DNA Methylase
HFCLIPBE_01671 9.1e-18 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HFCLIPBE_01673 2.5e-79 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HFCLIPBE_01676 4.2e-28 2.1.1.72 H Adenine-specific methyltransferase EcoRI
HFCLIPBE_01677 8e-68 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HFCLIPBE_01678 6.1e-11 S Protein of unknown function (DUF2815)
HFCLIPBE_01682 4.7e-11 S Protein of unknown function (DUF2815)
HFCLIPBE_01687 1.7e-17 S PIN domain
HFCLIPBE_01689 1.2e-237 D ftsk spoiiie
HFCLIPBE_01691 1.2e-13
HFCLIPBE_01692 8.6e-59 addB 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HFCLIPBE_01695 5.8e-42 D protein tyrosine kinase activity
HFCLIPBE_01697 4.1e-28
HFCLIPBE_01698 8.1e-188 S COG0433 Predicted ATPase
HFCLIPBE_01699 1.6e-37 dnaN 2.7.7.7 L DNA-directed DNA polymerase activity
HFCLIPBE_01707 2.1e-28
HFCLIPBE_01712 9.1e-59 L COGs COG0675 Transposase and inactivated derivatives
HFCLIPBE_01713 2.6e-26 L Transposase
HFCLIPBE_01715 2.8e-88 XK27_08050 O prohibitin homologues
HFCLIPBE_01716 1.9e-27 S Bifunctional DNA primase/polymerase, N-terminal
HFCLIPBE_01718 4.2e-143 L Psort location Cytoplasmic, score 8.87
HFCLIPBE_01720 9.4e-28 2.1.1.72 S Adenine-specific methyltransferase EcoRI
HFCLIPBE_01723 6.2e-120 V Protein of unknown function DUF262
HFCLIPBE_01724 5.8e-104 2.1.1.72 S Psort location Cytoplasmic, score 8.96
HFCLIPBE_01725 5.1e-11 L Transposase
HFCLIPBE_01726 1.2e-12 relB L RelB antitoxin
HFCLIPBE_01727 1.5e-89
HFCLIPBE_01728 8e-150 2.1.1.72 L DNA methylase
HFCLIPBE_01729 1.8e-193 purL 1.17.4.1, 6.3.5.3 L intein-mediated protein splicing
HFCLIPBE_01733 8.1e-47 S N-methyltransferase activity
HFCLIPBE_01736 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
HFCLIPBE_01737 2.7e-140 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFCLIPBE_01738 2.9e-73 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HFCLIPBE_01739 8.6e-23
HFCLIPBE_01740 3.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HFCLIPBE_01741 5.9e-146
HFCLIPBE_01742 2.5e-156 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HFCLIPBE_01743 6.9e-207 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HFCLIPBE_01744 8.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFCLIPBE_01745 4.4e-14 yajC U Preprotein translocase subunit
HFCLIPBE_01746 9.5e-184 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFCLIPBE_01747 3.1e-86 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFCLIPBE_01748 6.5e-94 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HFCLIPBE_01749 3.8e-118 yebC K transcriptional regulatory protein
HFCLIPBE_01750 9.1e-183 pimA 2.4.1.345 GT4 M Glycosyl transferases group 1
HFCLIPBE_01751 9.2e-144 htrB 2.3.1.241, 2.3.1.265 M Bacterial lipid A biosynthesis acyltransferase
HFCLIPBE_01752 5.1e-90 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
HFCLIPBE_01753 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFCLIPBE_01758 8.7e-30 L Phage integrase family
HFCLIPBE_01763 2.8e-127 S PAC2 family
HFCLIPBE_01765 3.2e-57 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
HFCLIPBE_01766 2.2e-07 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFCLIPBE_01767 5.2e-154 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFCLIPBE_01768 1.1e-147 G Fructosamine kinase
HFCLIPBE_01769 1.2e-192 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFCLIPBE_01770 4.2e-163 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFCLIPBE_01771 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
HFCLIPBE_01772 3.4e-200 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HFCLIPBE_01773 7.4e-246 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HFCLIPBE_01774 4e-141 S Sucrose-6F-phosphate phosphohydrolase
HFCLIPBE_01775 2.6e-34 secG U Preprotein translocase SecG subunit
HFCLIPBE_01776 9.8e-133 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFCLIPBE_01777 2.1e-219 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
HFCLIPBE_01778 7.5e-170 whiA K May be required for sporulation
HFCLIPBE_01779 7.9e-158 rapZ S Displays ATPase and GTPase activities
HFCLIPBE_01780 6.5e-121 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
HFCLIPBE_01781 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFCLIPBE_01782 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFCLIPBE_01783 1.9e-300 ybiT S ABC transporter
HFCLIPBE_01784 5.4e-119 E GDSL-like Lipase/Acylhydrolase family
HFCLIPBE_01785 1.5e-277 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFCLIPBE_01786 3.7e-51 S Protein of unknown function (DUF4232)
HFCLIPBE_01787 1.3e-85 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HFCLIPBE_01788 3e-170 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
HFCLIPBE_01789 4.6e-118 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFCLIPBE_01790 1.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFCLIPBE_01791 2.7e-146 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HFCLIPBE_01792 7.1e-162 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
HFCLIPBE_01793 7.8e-258 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFCLIPBE_01794 1.2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HFCLIPBE_01795 8.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HFCLIPBE_01796 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HFCLIPBE_01797 6.6e-159 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
HFCLIPBE_01798 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFCLIPBE_01799 1.4e-80 sixA T Phosphoglycerate mutase family
HFCLIPBE_01800 9.4e-166 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HFCLIPBE_01801 6.6e-144 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
HFCLIPBE_01802 1.1e-45 ybjQ S Putative heavy-metal-binding
HFCLIPBE_01804 8.7e-48 azlD E Branched-chain amino acid transport protein (AzlD)
HFCLIPBE_01805 2.9e-116 azlC E AzlC protein
HFCLIPBE_01806 0.0 fadD1 6.2.1.3 I AMP-binding enzyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)