ORF_ID e_value Gene_name EC_number CAZy COGs Description
COFIPFKD_00001 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COFIPFKD_00002 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
COFIPFKD_00003 1.5e-102 srtA 3.4.22.70 M sortase family
COFIPFKD_00004 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COFIPFKD_00005 5.9e-24
COFIPFKD_00006 1e-172 M Glycosyl hydrolases family 25
COFIPFKD_00007 8.6e-29
COFIPFKD_00008 7.9e-19
COFIPFKD_00010 1.1e-07
COFIPFKD_00011 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
COFIPFKD_00012 3.1e-38
COFIPFKD_00018 1.6e-36
COFIPFKD_00019 1.1e-08
COFIPFKD_00020 1.7e-125 Z012_12235 S Baseplate J-like protein
COFIPFKD_00021 9.5e-33
COFIPFKD_00022 1.2e-48
COFIPFKD_00023 5.7e-104
COFIPFKD_00024 2.1e-46
COFIPFKD_00025 1.2e-58 M LysM domain
COFIPFKD_00026 0.0 3.4.14.13 M Phage tail tape measure protein TP901
COFIPFKD_00028 9e-27
COFIPFKD_00029 4e-56
COFIPFKD_00030 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
COFIPFKD_00031 8e-57
COFIPFKD_00032 2.9e-45
COFIPFKD_00033 1.5e-75
COFIPFKD_00034 2.1e-30 S Protein of unknown function (DUF4054)
COFIPFKD_00035 3.5e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
COFIPFKD_00036 1.6e-58
COFIPFKD_00037 1.1e-86 S Uncharacterized protein conserved in bacteria (DUF2213)
COFIPFKD_00038 1.1e-07 S Lysin motif
COFIPFKD_00039 1e-97 S Phage Mu protein F like protein
COFIPFKD_00040 7e-142 S Protein of unknown function (DUF1073)
COFIPFKD_00041 1.8e-230 S Terminase-like family
COFIPFKD_00042 1.5e-28 L Terminase small subunit
COFIPFKD_00043 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
COFIPFKD_00044 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
COFIPFKD_00052 2.1e-14
COFIPFKD_00053 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
COFIPFKD_00059 1.4e-51 dnaC L IstB-like ATP binding protein
COFIPFKD_00060 2.7e-34 S Conserved phage C-terminus (Phg_2220_C)
COFIPFKD_00061 6.5e-57 S Protein of unknown function (DUF1071)
COFIPFKD_00065 5e-07 K Helix-turn-helix XRE-family like proteins
COFIPFKD_00066 7.2e-10
COFIPFKD_00071 1.5e-95 S AntA/AntB antirepressor
COFIPFKD_00072 2.3e-12
COFIPFKD_00077 1.3e-81 S DNA binding
COFIPFKD_00078 9.5e-12 K Helix-turn-helix XRE-family like proteins
COFIPFKD_00079 6.5e-23 K Cro/C1-type HTH DNA-binding domain
COFIPFKD_00080 2.5e-18 S Pfam:Peptidase_M78
COFIPFKD_00085 1.6e-20 S YjcQ protein
COFIPFKD_00086 4.2e-180 sip L Belongs to the 'phage' integrase family
COFIPFKD_00087 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COFIPFKD_00088 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COFIPFKD_00089 0.0 dnaK O Heat shock 70 kDa protein
COFIPFKD_00090 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COFIPFKD_00091 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COFIPFKD_00092 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COFIPFKD_00093 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COFIPFKD_00094 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COFIPFKD_00095 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COFIPFKD_00096 3.2e-47 rplGA J ribosomal protein
COFIPFKD_00097 8.8e-47 ylxR K Protein of unknown function (DUF448)
COFIPFKD_00098 1.4e-196 nusA K Participates in both transcription termination and antitermination
COFIPFKD_00099 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
COFIPFKD_00100 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COFIPFKD_00101 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COFIPFKD_00102 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
COFIPFKD_00103 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
COFIPFKD_00104 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COFIPFKD_00105 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COFIPFKD_00106 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COFIPFKD_00107 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COFIPFKD_00108 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
COFIPFKD_00109 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
COFIPFKD_00110 2.9e-116 plsC 2.3.1.51 I Acyltransferase
COFIPFKD_00111 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
COFIPFKD_00112 0.0 pepO 3.4.24.71 O Peptidase family M13
COFIPFKD_00113 0.0 mdlB V ABC transporter
COFIPFKD_00114 5.2e-66 mdlA V ABC transporter
COFIPFKD_00115 8.8e-164 L An automated process has identified a potential problem with this gene model
COFIPFKD_00116 2.9e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
COFIPFKD_00117 7.1e-46
COFIPFKD_00118 3.1e-148 glcU U sugar transport
COFIPFKD_00119 3.7e-250 lctP C L-lactate permease
COFIPFKD_00120 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COFIPFKD_00121 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COFIPFKD_00122 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COFIPFKD_00123 1.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COFIPFKD_00124 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COFIPFKD_00125 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COFIPFKD_00126 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COFIPFKD_00127 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COFIPFKD_00128 1.5e-102 GM NmrA-like family
COFIPFKD_00129 1.6e-73 L Transposase
COFIPFKD_00130 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COFIPFKD_00131 3.5e-32 ykzG S Belongs to the UPF0356 family
COFIPFKD_00132 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COFIPFKD_00133 0.0 typA T GTP-binding protein TypA
COFIPFKD_00134 5.9e-211 ftsW D Belongs to the SEDS family
COFIPFKD_00135 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
COFIPFKD_00136 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
COFIPFKD_00137 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COFIPFKD_00138 2.4e-187 ylbL T Belongs to the peptidase S16 family
COFIPFKD_00139 3.1e-79 comEA L Competence protein ComEA
COFIPFKD_00140 0.0 comEC S Competence protein ComEC
COFIPFKD_00141 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
COFIPFKD_00142 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
COFIPFKD_00143 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COFIPFKD_00144 6.4e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COFIPFKD_00145 1.3e-148
COFIPFKD_00146 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COFIPFKD_00147 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COFIPFKD_00148 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COFIPFKD_00149 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
COFIPFKD_00150 7.8e-39 yjeM E Amino Acid
COFIPFKD_00151 3.4e-175 yjeM E Amino Acid
COFIPFKD_00152 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COFIPFKD_00153 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
COFIPFKD_00154 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COFIPFKD_00155 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COFIPFKD_00156 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COFIPFKD_00157 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COFIPFKD_00158 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COFIPFKD_00159 2.7e-216 aspC 2.6.1.1 E Aminotransferase
COFIPFKD_00160 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COFIPFKD_00161 2.1e-194 pbpX1 V Beta-lactamase
COFIPFKD_00162 1.2e-299 I Protein of unknown function (DUF2974)
COFIPFKD_00163 8e-227 L COG3547 Transposase and inactivated derivatives
COFIPFKD_00164 1.2e-210 S Bacterial protein of unknown function (DUF871)
COFIPFKD_00166 2.3e-43 ybhL S Belongs to the BI1 family
COFIPFKD_00167 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
COFIPFKD_00168 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COFIPFKD_00169 9.7e-52 S Iron-sulfur cluster assembly protein
COFIPFKD_00170 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COFIPFKD_00171 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COFIPFKD_00172 8.5e-279 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
COFIPFKD_00174 6.9e-129 L Transposase
COFIPFKD_00175 3.3e-153 L Transposase
COFIPFKD_00176 1.2e-57 L Transposase
COFIPFKD_00177 4.4e-103 K Putative DNA-binding domain
COFIPFKD_00178 9.3e-35
COFIPFKD_00179 2e-157 S reductase
COFIPFKD_00180 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
COFIPFKD_00181 1.9e-138 2.4.2.3 F Phosphorylase superfamily
COFIPFKD_00182 9e-144 2.4.2.3 F Phosphorylase superfamily
COFIPFKD_00183 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
COFIPFKD_00184 3e-24
COFIPFKD_00185 1.5e-152
COFIPFKD_00186 1.6e-33 G Peptidase_C39 like family
COFIPFKD_00187 4.4e-163 M NlpC/P60 family
COFIPFKD_00188 1e-91 G Peptidase_C39 like family
COFIPFKD_00189 2.2e-85 S PFAM Archaeal ATPase
COFIPFKD_00190 5.7e-84 S PFAM Archaeal ATPase
COFIPFKD_00191 7.7e-26
COFIPFKD_00192 3.1e-71 2.5.1.74 H UbiA prenyltransferase family
COFIPFKD_00193 2.6e-18 ybgG 3.2.1.170 GH38 G PFAM Glycosyl hydrolases family 38 C-terminal domain
COFIPFKD_00194 1.4e-150 mngA 2.7.1.195, 2.7.1.202 U system, fructose-specific IIC component
COFIPFKD_00195 5.3e-37 mngA 2.7.1.195, 2.7.1.202 G Psort location Cytoplasmic, score 9.98
COFIPFKD_00196 2e-42 fryA 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COFIPFKD_00197 1.5e-141 msmE G Bacterial extracellular solute-binding protein
COFIPFKD_00198 1.7e-160 scrR K Periplasmic binding protein domain
COFIPFKD_00199 5.5e-36
COFIPFKD_00200 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
COFIPFKD_00201 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COFIPFKD_00202 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COFIPFKD_00203 7.2e-56 yheA S Belongs to the UPF0342 family
COFIPFKD_00204 1e-226 yhaO L Ser Thr phosphatase family protein
COFIPFKD_00205 0.0 L AAA domain
COFIPFKD_00206 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
COFIPFKD_00207 2.9e-23
COFIPFKD_00208 4.1e-51 S Domain of unknown function DUF1829
COFIPFKD_00209 1.1e-265
COFIPFKD_00210 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
COFIPFKD_00211 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COFIPFKD_00212 3.9e-25
COFIPFKD_00213 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
COFIPFKD_00214 5.7e-135 ecsA V ABC transporter, ATP-binding protein
COFIPFKD_00215 6.5e-221 ecsB U ABC transporter
COFIPFKD_00216 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COFIPFKD_00218 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
COFIPFKD_00219 1.4e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COFIPFKD_00220 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
COFIPFKD_00221 6.9e-218 mepA V MATE efflux family protein
COFIPFKD_00222 1.8e-176 S SLAP domain
COFIPFKD_00223 4.4e-283 M Peptidase family M1 domain
COFIPFKD_00224 4.5e-188 S Bacteriocin helveticin-J
COFIPFKD_00225 8e-51 L RelB antitoxin
COFIPFKD_00226 7.4e-105 qmcA O prohibitin homologues
COFIPFKD_00227 3.5e-25 qmcA O prohibitin homologues
COFIPFKD_00228 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COFIPFKD_00229 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COFIPFKD_00230 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COFIPFKD_00231 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COFIPFKD_00232 5.1e-251 dnaB L Replication initiation and membrane attachment
COFIPFKD_00233 2.1e-168 dnaI L Primosomal protein DnaI
COFIPFKD_00234 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COFIPFKD_00235 3.3e-61 3.6.1.55 F NUDIX domain
COFIPFKD_00236 1e-79 S AAA domain
COFIPFKD_00237 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
COFIPFKD_00238 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
COFIPFKD_00239 1.7e-271 V ABC-type multidrug transport system, ATPase and permease components
COFIPFKD_00240 0.0 L Plasmid pRiA4b ORF-3-like protein
COFIPFKD_00241 3.7e-174 L Bifunctional protein
COFIPFKD_00242 2.7e-227 L Transposase
COFIPFKD_00244 9.9e-24 K Helix-turn-helix XRE-family like proteins
COFIPFKD_00245 2.5e-75 K Helix-turn-helix domain
COFIPFKD_00246 3.3e-127 L PFAM transposase IS116 IS110 IS902
COFIPFKD_00247 5.3e-17 yoaK S Protein of unknown function (DUF1275)
COFIPFKD_00248 6.4e-88 yoaK S Protein of unknown function (DUF1275)
COFIPFKD_00249 6.1e-227 L COG3547 Transposase and inactivated derivatives
COFIPFKD_00250 3e-270 L Transposase DDE domain
COFIPFKD_00251 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
COFIPFKD_00252 1.6e-294 L Nuclease-related domain
COFIPFKD_00253 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COFIPFKD_00254 8.3e-106 S Repeat protein
COFIPFKD_00255 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
COFIPFKD_00256 5.6e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COFIPFKD_00257 5.4e-56 XK27_04120 S Putative amino acid metabolism
COFIPFKD_00258 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
COFIPFKD_00259 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COFIPFKD_00260 6.7e-37
COFIPFKD_00261 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
COFIPFKD_00262 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
COFIPFKD_00263 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COFIPFKD_00264 2.8e-74 gpsB D DivIVA domain protein
COFIPFKD_00265 5.7e-149 ylmH S S4 domain protein
COFIPFKD_00266 1.7e-45 yggT S YGGT family
COFIPFKD_00267 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COFIPFKD_00268 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COFIPFKD_00269 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COFIPFKD_00270 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COFIPFKD_00271 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COFIPFKD_00272 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COFIPFKD_00273 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COFIPFKD_00274 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
COFIPFKD_00275 1.8e-54 ftsL D Cell division protein FtsL
COFIPFKD_00276 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COFIPFKD_00277 6.3e-78 mraZ K Belongs to the MraZ family
COFIPFKD_00278 6.4e-54 S Protein of unknown function (DUF3397)
COFIPFKD_00280 2.7e-94 mreD
COFIPFKD_00281 2e-147 mreC M Involved in formation and maintenance of cell shape
COFIPFKD_00282 2.4e-176 mreB D cell shape determining protein MreB
COFIPFKD_00283 2.3e-108 radC L DNA repair protein
COFIPFKD_00284 5.7e-126 S Haloacid dehalogenase-like hydrolase
COFIPFKD_00285 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COFIPFKD_00286 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COFIPFKD_00287 4.3e-136 S Alpha/beta hydrolase family
COFIPFKD_00288 4.5e-94 rimL J Acetyltransferase (GNAT) domain
COFIPFKD_00289 4e-33 S Domain of unknown function DUF87
COFIPFKD_00290 2e-21 L Transposase
COFIPFKD_00291 7.9e-50 L COG2826 Transposase and inactivated derivatives, IS30 family
COFIPFKD_00292 9.8e-58 L COG2826 Transposase and inactivated derivatives, IS30 family
COFIPFKD_00293 4.7e-183 L DDE superfamily endonuclease
COFIPFKD_00295 3.8e-139 pnuC H nicotinamide mononucleotide transporter
COFIPFKD_00296 2e-219 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
COFIPFKD_00299 5.8e-100 L Transposase
COFIPFKD_00300 1.9e-39 S Transglycosylase associated protein
COFIPFKD_00301 8.5e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COFIPFKD_00302 2.5e-08 S Protein of unknown function (DUF3021)
COFIPFKD_00303 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
COFIPFKD_00304 2.5e-52
COFIPFKD_00305 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
COFIPFKD_00306 0.0 3.6.3.8 P P-type ATPase
COFIPFKD_00308 6.5e-44
COFIPFKD_00309 1.5e-94 S Protein of unknown function (DUF3990)
COFIPFKD_00310 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
COFIPFKD_00311 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
COFIPFKD_00312 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COFIPFKD_00313 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COFIPFKD_00314 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
COFIPFKD_00315 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COFIPFKD_00316 7.4e-214 iscS2 2.8.1.7 E Aminotransferase class V
COFIPFKD_00317 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COFIPFKD_00318 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COFIPFKD_00319 1.3e-84 yueI S Protein of unknown function (DUF1694)
COFIPFKD_00320 2.2e-238 rarA L recombination factor protein RarA
COFIPFKD_00321 8.4e-39
COFIPFKD_00322 1.8e-78 usp6 T universal stress protein
COFIPFKD_00323 4.7e-216 rodA D Belongs to the SEDS family
COFIPFKD_00324 3.3e-33 S Protein of unknown function (DUF2969)
COFIPFKD_00325 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
COFIPFKD_00326 1.2e-177 mbl D Cell shape determining protein MreB Mrl
COFIPFKD_00327 2e-30 ywzB S Protein of unknown function (DUF1146)
COFIPFKD_00328 4.5e-71 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COFIPFKD_00329 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COFIPFKD_00330 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COFIPFKD_00331 2.8e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COFIPFKD_00332 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COFIPFKD_00333 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COFIPFKD_00334 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COFIPFKD_00335 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
COFIPFKD_00336 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COFIPFKD_00337 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COFIPFKD_00338 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COFIPFKD_00339 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COFIPFKD_00340 1.3e-113 tdk 2.7.1.21 F thymidine kinase
COFIPFKD_00341 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
COFIPFKD_00344 3.9e-195 ampC V Beta-lactamase
COFIPFKD_00345 5.1e-155 mdtG EGP Major facilitator Superfamily
COFIPFKD_00346 2.8e-134 S Uncharacterised protein family (UPF0236)
COFIPFKD_00347 9.9e-82 C Flavodoxin
COFIPFKD_00348 1.7e-30 ybbH_2 K rpiR family
COFIPFKD_00349 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
COFIPFKD_00350 5.4e-13
COFIPFKD_00351 1.1e-87 L PFAM transposase, IS4 family protein
COFIPFKD_00352 7.5e-103 G Phosphoglycerate mutase family
COFIPFKD_00353 5.7e-236 S Uncharacterized protein conserved in bacteria (DUF2325)
COFIPFKD_00354 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COFIPFKD_00355 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
COFIPFKD_00356 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
COFIPFKD_00357 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COFIPFKD_00358 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COFIPFKD_00359 3.4e-71 yqhY S Asp23 family, cell envelope-related function
COFIPFKD_00360 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COFIPFKD_00361 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COFIPFKD_00362 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COFIPFKD_00363 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COFIPFKD_00364 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COFIPFKD_00365 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
COFIPFKD_00366 1.7e-299 recN L May be involved in recombinational repair of damaged DNA
COFIPFKD_00367 1.1e-77 6.3.3.2 S ASCH
COFIPFKD_00368 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
COFIPFKD_00369 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COFIPFKD_00370 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COFIPFKD_00371 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COFIPFKD_00372 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COFIPFKD_00373 1.1e-138 stp 3.1.3.16 T phosphatase
COFIPFKD_00374 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
COFIPFKD_00375 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COFIPFKD_00376 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
COFIPFKD_00377 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
COFIPFKD_00378 1.4e-30
COFIPFKD_00379 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
COFIPFKD_00380 1.5e-56 asp S Asp23 family, cell envelope-related function
COFIPFKD_00381 7.6e-305 yloV S DAK2 domain fusion protein YloV
COFIPFKD_00382 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COFIPFKD_00383 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COFIPFKD_00384 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COFIPFKD_00385 3.1e-192 oppD P Belongs to the ABC transporter superfamily
COFIPFKD_00386 1.5e-170 oppF P Belongs to the ABC transporter superfamily
COFIPFKD_00387 2.6e-172 oppB P ABC transporter permease
COFIPFKD_00388 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
COFIPFKD_00389 9.7e-46 oppA E ABC transporter substrate-binding protein
COFIPFKD_00390 1.1e-70 EGP Major facilitator Superfamily
COFIPFKD_00391 5.4e-60 S Uncharacterised protein family (UPF0236)
COFIPFKD_00392 9.4e-46
COFIPFKD_00393 1.2e-12 D Alpha beta
COFIPFKD_00394 6.5e-16 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
COFIPFKD_00395 2.4e-36 L An automated process has identified a potential problem with this gene model
COFIPFKD_00396 6.1e-269 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
COFIPFKD_00397 1.2e-127 K LytTr DNA-binding domain
COFIPFKD_00398 4.4e-138 2.7.13.3 T GHKL domain
COFIPFKD_00399 1.2e-16
COFIPFKD_00400 2.1e-255 S Archaea bacterial proteins of unknown function
COFIPFKD_00401 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
COFIPFKD_00402 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
COFIPFKD_00403 2.3e-24
COFIPFKD_00404 9.5e-26
COFIPFKD_00405 2.5e-33
COFIPFKD_00406 1.4e-53 S Enterocin A Immunity
COFIPFKD_00407 6.3e-139 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
COFIPFKD_00408 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COFIPFKD_00409 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
COFIPFKD_00410 9.6e-121 K response regulator
COFIPFKD_00412 0.0 V ABC transporter
COFIPFKD_00413 4.2e-144 V ABC transporter, ATP-binding protein
COFIPFKD_00414 1.2e-145 V ABC transporter, ATP-binding protein
COFIPFKD_00415 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
COFIPFKD_00416 1e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COFIPFKD_00417 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
COFIPFKD_00418 1.5e-153 spo0J K Belongs to the ParB family
COFIPFKD_00419 3.4e-138 soj D Sporulation initiation inhibitor
COFIPFKD_00420 5e-148 noc K Belongs to the ParB family
COFIPFKD_00421 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
COFIPFKD_00422 9.1e-66 L An automated process has identified a potential problem with this gene model
COFIPFKD_00423 3e-53 cvpA S Colicin V production protein
COFIPFKD_00425 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COFIPFKD_00426 6e-151 3.1.3.48 T Tyrosine phosphatase family
COFIPFKD_00427 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
COFIPFKD_00428 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
COFIPFKD_00429 2.4e-110 K WHG domain
COFIPFKD_00430 3e-37
COFIPFKD_00433 6.6e-72 L Transposase
COFIPFKD_00434 4.5e-49 L An automated process has identified a potential problem with this gene model
COFIPFKD_00435 1.1e-183 scrR K helix_turn _helix lactose operon repressor
COFIPFKD_00436 3.7e-295 scrB 3.2.1.26 GH32 G invertase
COFIPFKD_00437 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
COFIPFKD_00438 2.3e-181 M CHAP domain
COFIPFKD_00439 3.5e-75
COFIPFKD_00440 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COFIPFKD_00441 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COFIPFKD_00442 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COFIPFKD_00443 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COFIPFKD_00444 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COFIPFKD_00445 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COFIPFKD_00446 9.6e-41 yajC U Preprotein translocase
COFIPFKD_00447 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COFIPFKD_00448 1.7e-215 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COFIPFKD_00449 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
COFIPFKD_00450 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COFIPFKD_00451 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COFIPFKD_00452 2e-42 yrzL S Belongs to the UPF0297 family
COFIPFKD_00453 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COFIPFKD_00454 1.1e-50 yrzB S Belongs to the UPF0473 family
COFIPFKD_00455 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COFIPFKD_00456 3.5e-54 trxA O Belongs to the thioredoxin family
COFIPFKD_00457 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COFIPFKD_00458 1.1e-71 yslB S Protein of unknown function (DUF2507)
COFIPFKD_00459 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COFIPFKD_00460 2.4e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COFIPFKD_00461 7.7e-30 ropB K Helix-turn-helix domain
COFIPFKD_00462 5.7e-154 pstA P Phosphate transport system permease protein PstA
COFIPFKD_00463 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COFIPFKD_00464 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COFIPFKD_00465 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
COFIPFKD_00466 2.8e-90 L An automated process has identified a potential problem with this gene model
COFIPFKD_00467 1.5e-11 GT2,GT4 M family 8
COFIPFKD_00468 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COFIPFKD_00469 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COFIPFKD_00470 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
COFIPFKD_00471 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
COFIPFKD_00472 9e-26
COFIPFKD_00473 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COFIPFKD_00474 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COFIPFKD_00475 5.7e-106 2.4.1.58 GT8 M family 8
COFIPFKD_00476 1.3e-34 M lipopolysaccharide 3-alpha-galactosyltransferase activity
COFIPFKD_00477 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COFIPFKD_00478 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COFIPFKD_00479 1.1e-34 S Protein of unknown function (DUF2508)
COFIPFKD_00480 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COFIPFKD_00481 8.9e-53 yaaQ S Cyclic-di-AMP receptor
COFIPFKD_00482 1.5e-155 holB 2.7.7.7 L DNA polymerase III
COFIPFKD_00483 1.8e-59 yabA L Involved in initiation control of chromosome replication
COFIPFKD_00484 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COFIPFKD_00485 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
COFIPFKD_00486 2.2e-85 S ECF transporter, substrate-specific component
COFIPFKD_00487 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
COFIPFKD_00488 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
COFIPFKD_00489 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COFIPFKD_00490 1.1e-187 L Transposase IS66 family
COFIPFKD_00491 8.7e-34 S Transposase C of IS166 homeodomain
COFIPFKD_00492 9.3e-64 L PFAM IS66 Orf2 family protein
COFIPFKD_00493 7.7e-22
COFIPFKD_00494 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COFIPFKD_00495 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COFIPFKD_00496 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
COFIPFKD_00497 0.0 uup S ABC transporter, ATP-binding protein
COFIPFKD_00498 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COFIPFKD_00499 4.7e-228 L COG3547 Transposase and inactivated derivatives
COFIPFKD_00500 6.4e-243 cydA 1.10.3.14 C ubiquinol oxidase
COFIPFKD_00501 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
COFIPFKD_00502 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
COFIPFKD_00503 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
COFIPFKD_00504 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
COFIPFKD_00505 6.1e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COFIPFKD_00506 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
COFIPFKD_00507 1.5e-230 ndh 1.6.99.3 C NADH dehydrogenase
COFIPFKD_00508 6.2e-43 1.3.5.4 C FAD binding domain
COFIPFKD_00509 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COFIPFKD_00510 2.8e-168 K LysR substrate binding domain
COFIPFKD_00511 1.1e-121 3.6.1.27 I Acid phosphatase homologues
COFIPFKD_00512 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COFIPFKD_00513 4.7e-275 ytgP S Polysaccharide biosynthesis protein
COFIPFKD_00514 1.4e-191 oppA E ABC transporter, substratebinding protein
COFIPFKD_00515 1.3e-30
COFIPFKD_00516 4.2e-145 pstS P Phosphate
COFIPFKD_00517 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
COFIPFKD_00518 1.2e-152 pstA P Phosphate transport system permease protein PstA
COFIPFKD_00519 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COFIPFKD_00520 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
COFIPFKD_00521 9.5e-121 T Transcriptional regulatory protein, C terminal
COFIPFKD_00522 1.1e-282 phoR 2.7.13.3 T Histidine kinase
COFIPFKD_00523 1e-95
COFIPFKD_00524 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
COFIPFKD_00526 4.5e-185 3.2.1.18 GH33 M Rib/alpha-like repeat
COFIPFKD_00527 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
COFIPFKD_00528 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COFIPFKD_00530 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COFIPFKD_00531 2.4e-43 K Helix-turn-helix
COFIPFKD_00532 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COFIPFKD_00533 1.4e-226 pbuX F xanthine permease
COFIPFKD_00534 2.5e-152 msmR K AraC-like ligand binding domain
COFIPFKD_00535 4.4e-285 pipD E Dipeptidase
COFIPFKD_00536 1.8e-74 K acetyltransferase
COFIPFKD_00537 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COFIPFKD_00538 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COFIPFKD_00539 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COFIPFKD_00540 6.9e-69 S Domain of unknown function (DUF1934)
COFIPFKD_00541 3.2e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
COFIPFKD_00542 5.6e-43
COFIPFKD_00543 4.2e-172 2.7.1.2 GK ROK family
COFIPFKD_00544 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COFIPFKD_00545 7.8e-292 S SLAP domain
COFIPFKD_00546 5.3e-80
COFIPFKD_00547 9.7e-231 potE E amino acid
COFIPFKD_00548 9.5e-228 L Transposase
COFIPFKD_00549 5.5e-148 S cog cog1373
COFIPFKD_00550 0.0 4.2.1.53 S Myosin-crossreactive antigen
COFIPFKD_00551 2e-91 yxdD K Bacterial regulatory proteins, tetR family
COFIPFKD_00552 1.9e-259 emrY EGP Major facilitator Superfamily
COFIPFKD_00557 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
COFIPFKD_00558 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COFIPFKD_00559 6.3e-201 pbpX V Beta-lactamase
COFIPFKD_00560 2.8e-244 nhaC C Na H antiporter NhaC
COFIPFKD_00561 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
COFIPFKD_00562 2.6e-57
COFIPFKD_00563 4.3e-108 ybhL S Belongs to the BI1 family
COFIPFKD_00564 2.7e-171 yegS 2.7.1.107 G Lipid kinase
COFIPFKD_00565 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COFIPFKD_00566 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COFIPFKD_00567 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COFIPFKD_00568 5.8e-203 camS S sex pheromone
COFIPFKD_00569 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COFIPFKD_00570 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
COFIPFKD_00571 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
COFIPFKD_00573 4.1e-83 ydcK S Belongs to the SprT family
COFIPFKD_00574 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
COFIPFKD_00575 3e-257 epsU S Polysaccharide biosynthesis protein
COFIPFKD_00576 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COFIPFKD_00577 0.0 pacL 3.6.3.8 P P-type ATPase
COFIPFKD_00578 1.4e-204 tnpB L Putative transposase DNA-binding domain
COFIPFKD_00579 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COFIPFKD_00580 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COFIPFKD_00581 1.7e-204 csaB M Glycosyl transferases group 1
COFIPFKD_00582 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
COFIPFKD_00583 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
COFIPFKD_00584 4.6e-123 gntR1 K UTRA
COFIPFKD_00585 1.6e-178
COFIPFKD_00586 3.4e-45 oppA2 E ABC transporter, substratebinding protein
COFIPFKD_00587 4.4e-239 oppA2 E ABC transporter, substratebinding protein
COFIPFKD_00590 3.2e-240 npr 1.11.1.1 C NADH oxidase
COFIPFKD_00591 7.7e-12
COFIPFKD_00592 3.7e-22 3.6.4.12 S transposase or invertase
COFIPFKD_00593 6.7e-228 slpX S SLAP domain
COFIPFKD_00594 4.4e-144 K SIS domain
COFIPFKD_00595 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
COFIPFKD_00596 1.8e-184 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
COFIPFKD_00597 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
COFIPFKD_00599 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
COFIPFKD_00601 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COFIPFKD_00602 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
COFIPFKD_00603 9.3e-69 G Histidine phosphatase superfamily (branch 1)
COFIPFKD_00604 1.2e-105 G Phosphoglycerate mutase family
COFIPFKD_00605 4.7e-159 D nuclear chromosome segregation
COFIPFKD_00606 5.8e-78 M LysM domain protein
COFIPFKD_00607 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COFIPFKD_00608 1.8e-125 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COFIPFKD_00609 6.2e-12
COFIPFKD_00610 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
COFIPFKD_00611 2.3e-30
COFIPFKD_00613 2.9e-69 S Iron-sulphur cluster biosynthesis
COFIPFKD_00614 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
COFIPFKD_00615 6.2e-59 psiE S Phosphate-starvation-inducible E
COFIPFKD_00617 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
COFIPFKD_00618 2.1e-227 amtB P ammonium transporter
COFIPFKD_00619 1.4e-60
COFIPFKD_00620 0.0 lhr L DEAD DEAH box helicase
COFIPFKD_00621 3.5e-244 P P-loop Domain of unknown function (DUF2791)
COFIPFKD_00622 3.7e-137 S TerB-C domain
COFIPFKD_00623 7.7e-29 hicA S HicA toxin of bacterial toxin-antitoxin,
COFIPFKD_00624 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
COFIPFKD_00625 4.7e-25 S Protein conserved in bacteria
COFIPFKD_00626 3.9e-57
COFIPFKD_00627 4.7e-85
COFIPFKD_00628 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
COFIPFKD_00629 5.8e-186 XK27_05540 S DUF218 domain
COFIPFKD_00630 1.1e-110
COFIPFKD_00631 4.3e-107
COFIPFKD_00632 1.2e-139 yicL EG EamA-like transporter family
COFIPFKD_00633 5e-165 EG EamA-like transporter family
COFIPFKD_00634 6.2e-163 EG EamA-like transporter family
COFIPFKD_00635 2e-32
COFIPFKD_00636 7.8e-38
COFIPFKD_00637 2.6e-155
COFIPFKD_00640 1.8e-81 M NlpC/P60 family
COFIPFKD_00641 2.1e-131 cobQ S glutamine amidotransferase
COFIPFKD_00642 6.5e-64 L RelB antitoxin
COFIPFKD_00643 1.1e-75 V ABC transporter transmembrane region
COFIPFKD_00644 2.9e-224 L transposase, IS605 OrfB family
COFIPFKD_00645 6.1e-136 V ABC transporter transmembrane region
COFIPFKD_00646 1.7e-184 G Transmembrane secretion effector
COFIPFKD_00647 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COFIPFKD_00648 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COFIPFKD_00649 6.3e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
COFIPFKD_00650 2e-177 yvdE K helix_turn _helix lactose operon repressor
COFIPFKD_00651 3.3e-20 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COFIPFKD_00652 5.2e-140 L An automated process has identified a potential problem with this gene model
COFIPFKD_00653 8.9e-145 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COFIPFKD_00654 6.1e-09 S PAS domain
COFIPFKD_00655 0.0 XK27_08315 M Sulfatase
COFIPFKD_00656 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COFIPFKD_00657 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COFIPFKD_00658 1.9e-98 G Aldose 1-epimerase
COFIPFKD_00659 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COFIPFKD_00660 2.1e-116
COFIPFKD_00661 2.1e-130
COFIPFKD_00662 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
COFIPFKD_00663 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
COFIPFKD_00664 0.0 yjbQ P TrkA C-terminal domain protein
COFIPFKD_00665 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
COFIPFKD_00666 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COFIPFKD_00668 3.6e-132 S SLAP domain
COFIPFKD_00670 5.3e-41
COFIPFKD_00671 1.2e-77 K DNA-templated transcription, initiation
COFIPFKD_00672 1.1e-25
COFIPFKD_00673 1.3e-141 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COFIPFKD_00674 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COFIPFKD_00675 2.5e-104 S SLAP domain
COFIPFKD_00676 4.3e-40 S Protein of unknown function (DUF2922)
COFIPFKD_00677 5.5e-30
COFIPFKD_00679 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COFIPFKD_00680 3.5e-175 S Cysteine-rich secretory protein family
COFIPFKD_00681 1.6e-41
COFIPFKD_00682 2.6e-118 M NlpC/P60 family
COFIPFKD_00683 1.4e-136 M NlpC P60 family protein
COFIPFKD_00684 5e-88 M NlpC/P60 family
COFIPFKD_00685 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
COFIPFKD_00686 3.9e-42
COFIPFKD_00687 2.9e-279 S O-antigen ligase like membrane protein
COFIPFKD_00688 3.3e-112
COFIPFKD_00689 1.4e-220 tnpB L Putative transposase DNA-binding domain
COFIPFKD_00690 5.5e-77 nrdI F NrdI Flavodoxin like
COFIPFKD_00691 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COFIPFKD_00692 2.5e-68
COFIPFKD_00693 9.1e-112 yvpB S Peptidase_C39 like family
COFIPFKD_00694 1.1e-83 S Threonine/Serine exporter, ThrE
COFIPFKD_00695 2.4e-136 thrE S Putative threonine/serine exporter
COFIPFKD_00696 8.9e-292 S ABC transporter
COFIPFKD_00697 8.3e-58
COFIPFKD_00698 5e-72 rimL J Acetyltransferase (GNAT) domain
COFIPFKD_00699 1.4e-34
COFIPFKD_00700 1.2e-30
COFIPFKD_00701 1.8e-111 S Protein of unknown function (DUF554)
COFIPFKD_00702 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COFIPFKD_00703 0.0 pepF E oligoendopeptidase F
COFIPFKD_00704 2.9e-31
COFIPFKD_00705 1.3e-69 doc S Prophage maintenance system killer protein
COFIPFKD_00708 4.6e-27 S Enterocin A Immunity
COFIPFKD_00709 1.7e-22 blpT
COFIPFKD_00710 2.8e-227 mdlA V ABC transporter
COFIPFKD_00711 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
COFIPFKD_00712 3e-38 ynzC S UPF0291 protein
COFIPFKD_00713 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COFIPFKD_00714 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
COFIPFKD_00715 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
COFIPFKD_00716 4.6e-213 S SLAP domain
COFIPFKD_00717 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COFIPFKD_00718 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COFIPFKD_00719 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COFIPFKD_00720 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COFIPFKD_00721 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COFIPFKD_00722 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COFIPFKD_00723 2.7e-258 yfnA E amino acid
COFIPFKD_00724 0.0 V FtsX-like permease family
COFIPFKD_00725 4.1e-133 cysA V ABC transporter, ATP-binding protein
COFIPFKD_00726 3.4e-23
COFIPFKD_00728 2.5e-288 pipD E Dipeptidase
COFIPFKD_00729 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COFIPFKD_00730 0.0 smc D Required for chromosome condensation and partitioning
COFIPFKD_00731 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COFIPFKD_00732 2.1e-308 oppA E ABC transporter substrate-binding protein
COFIPFKD_00733 3.1e-240 oppA E ABC transporter substrate-binding protein
COFIPFKD_00735 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
COFIPFKD_00736 1.7e-129 manY G PTS system
COFIPFKD_00737 1e-173 manN G system, mannose fructose sorbose family IID component
COFIPFKD_00738 1.1e-62 manO S Domain of unknown function (DUF956)
COFIPFKD_00739 3.3e-158 K Transcriptional regulator
COFIPFKD_00740 1.3e-85 maa S transferase hexapeptide repeat
COFIPFKD_00741 6.8e-243 cycA E Amino acid permease
COFIPFKD_00742 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
COFIPFKD_00743 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
COFIPFKD_00744 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COFIPFKD_00745 0.0 mtlR K Mga helix-turn-helix domain
COFIPFKD_00746 1.1e-306 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
COFIPFKD_00747 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COFIPFKD_00748 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
COFIPFKD_00749 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
COFIPFKD_00750 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
COFIPFKD_00751 2.1e-32
COFIPFKD_00752 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
COFIPFKD_00753 2.3e-156 K Helix-turn-helix XRE-family like proteins
COFIPFKD_00754 5.1e-165 V ABC transporter transmembrane region
COFIPFKD_00755 7.3e-115 V ABC transporter transmembrane region
COFIPFKD_00756 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
COFIPFKD_00757 1.7e-193 S TerB-C domain
COFIPFKD_00758 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
COFIPFKD_00759 0.0 G Belongs to the glycosyl hydrolase 31 family
COFIPFKD_00760 8.7e-145 I alpha/beta hydrolase fold
COFIPFKD_00761 4.9e-129 yibF S overlaps another CDS with the same product name
COFIPFKD_00762 2.2e-202 yibE S overlaps another CDS with the same product name
COFIPFKD_00763 1.4e-112
COFIPFKD_00764 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COFIPFKD_00765 6.4e-224 S Cysteine-rich secretory protein family
COFIPFKD_00766 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COFIPFKD_00767 1.3e-258 glnPH2 P ABC transporter permease
COFIPFKD_00768 2.8e-135
COFIPFKD_00769 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
COFIPFKD_00770 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COFIPFKD_00771 5.6e-36
COFIPFKD_00772 1.4e-140 L An automated process has identified a potential problem with this gene model
COFIPFKD_00773 7.3e-126 S Alpha/beta hydrolase family
COFIPFKD_00774 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
COFIPFKD_00775 2.2e-139 ypuA S Protein of unknown function (DUF1002)
COFIPFKD_00776 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COFIPFKD_00777 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
COFIPFKD_00778 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COFIPFKD_00779 9.3e-86
COFIPFKD_00780 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
COFIPFKD_00781 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COFIPFKD_00782 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
COFIPFKD_00783 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COFIPFKD_00784 3.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COFIPFKD_00785 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COFIPFKD_00786 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COFIPFKD_00787 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COFIPFKD_00788 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COFIPFKD_00789 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
COFIPFKD_00790 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COFIPFKD_00791 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COFIPFKD_00792 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COFIPFKD_00793 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COFIPFKD_00794 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COFIPFKD_00795 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COFIPFKD_00796 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COFIPFKD_00797 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COFIPFKD_00798 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COFIPFKD_00799 2.3e-24 rpmD J Ribosomal protein L30
COFIPFKD_00800 2.6e-71 rplO J Binds to the 23S rRNA
COFIPFKD_00801 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COFIPFKD_00802 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COFIPFKD_00803 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COFIPFKD_00804 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
COFIPFKD_00805 3.6e-55 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COFIPFKD_00806 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COFIPFKD_00807 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COFIPFKD_00808 1.4e-60 rplQ J Ribosomal protein L17
COFIPFKD_00809 3.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COFIPFKD_00810 4.6e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COFIPFKD_00811 7.2e-136 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COFIPFKD_00812 8.4e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COFIPFKD_00813 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COFIPFKD_00814 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
COFIPFKD_00815 3.7e-183 L Phage integrase family
COFIPFKD_00816 3.2e-225 L Transposase
COFIPFKD_00817 2.2e-22
COFIPFKD_00818 3.3e-140 repB EP Plasmid replication protein
COFIPFKD_00819 7.7e-79 S helix_turn_helix, Deoxyribose operon repressor
COFIPFKD_00821 1.7e-147
COFIPFKD_00822 1.5e-169
COFIPFKD_00823 2e-263 glnA 6.3.1.2 E glutamine synthetase
COFIPFKD_00824 7.8e-222 ynbB 4.4.1.1 P aluminum resistance
COFIPFKD_00825 1e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COFIPFKD_00826 1.5e-65 yqhL P Rhodanese-like protein
COFIPFKD_00827 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
COFIPFKD_00828 3.1e-119 gluP 3.4.21.105 S Rhomboid family
COFIPFKD_00829 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COFIPFKD_00830 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COFIPFKD_00831 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
COFIPFKD_00832 0.0 S membrane
COFIPFKD_00833 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
COFIPFKD_00834 1.3e-38 S RelB antitoxin
COFIPFKD_00835 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
COFIPFKD_00836 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COFIPFKD_00837 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
COFIPFKD_00838 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COFIPFKD_00839 8.7e-159 isdE P Periplasmic binding protein
COFIPFKD_00840 6.3e-123 M Iron Transport-associated domain
COFIPFKD_00841 3e-09 isdH M Iron Transport-associated domain
COFIPFKD_00842 8.4e-89
COFIPFKD_00843 1.4e-112 S SLAP domain
COFIPFKD_00844 1.2e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COFIPFKD_00845 2.6e-35 yaaA S S4 domain protein YaaA
COFIPFKD_00846 4e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COFIPFKD_00847 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COFIPFKD_00848 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COFIPFKD_00849 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
COFIPFKD_00850 2.7e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COFIPFKD_00851 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COFIPFKD_00852 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
COFIPFKD_00853 5.7e-69 rplI J Binds to the 23S rRNA
COFIPFKD_00854 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COFIPFKD_00855 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
COFIPFKD_00856 3.7e-168 degV S DegV family
COFIPFKD_00857 4.2e-135 V ABC transporter transmembrane region
COFIPFKD_00858 6.7e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
COFIPFKD_00860 1.4e-16
COFIPFKD_00861 1.6e-227 I Protein of unknown function (DUF2974)
COFIPFKD_00862 9.2e-119 yhiD S MgtC family
COFIPFKD_00864 3.8e-24 S SLAP domain
COFIPFKD_00865 4.3e-24 S SLAP domain
COFIPFKD_00867 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COFIPFKD_00868 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
COFIPFKD_00869 2.6e-186 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
COFIPFKD_00870 2.3e-198 oppD P Belongs to the ABC transporter superfamily
COFIPFKD_00871 1.9e-175 oppF P Belongs to the ABC transporter superfamily
COFIPFKD_00872 5.2e-256 pepC 3.4.22.40 E aminopeptidase
COFIPFKD_00873 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
COFIPFKD_00874 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COFIPFKD_00875 7.9e-112
COFIPFKD_00877 1.2e-111 E Belongs to the SOS response-associated peptidase family
COFIPFKD_00878 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
COFIPFKD_00879 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
COFIPFKD_00880 2e-103 S TPM domain
COFIPFKD_00881 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
COFIPFKD_00882 1e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
COFIPFKD_00883 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COFIPFKD_00884 1e-147 tatD L hydrolase, TatD family
COFIPFKD_00885 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COFIPFKD_00886 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COFIPFKD_00887 4.5e-39 veg S Biofilm formation stimulator VEG
COFIPFKD_00888 1.1e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
COFIPFKD_00889 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COFIPFKD_00890 8.2e-140 cof S haloacid dehalogenase-like hydrolase
COFIPFKD_00891 9.4e-72
COFIPFKD_00892 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
COFIPFKD_00893 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
COFIPFKD_00894 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COFIPFKD_00895 3.7e-159 yeaE S Aldo/keto reductase family
COFIPFKD_00896 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
COFIPFKD_00897 2.5e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
COFIPFKD_00898 1.3e-282 xylG 3.6.3.17 S ABC transporter
COFIPFKD_00899 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
COFIPFKD_00900 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
COFIPFKD_00901 2.8e-100 S ECF transporter, substrate-specific component
COFIPFKD_00902 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
COFIPFKD_00903 0.0 macB_3 V ABC transporter, ATP-binding protein
COFIPFKD_00904 1.6e-194 S DUF218 domain
COFIPFKD_00905 2.7e-120 S CAAX protease self-immunity
COFIPFKD_00906 3e-111 ropB K Transcriptional regulator
COFIPFKD_00907 4.2e-154 EGP Major facilitator Superfamily
COFIPFKD_00908 5.4e-51
COFIPFKD_00909 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
COFIPFKD_00910 4.1e-276 V ABC transporter transmembrane region
COFIPFKD_00911 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
COFIPFKD_00912 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COFIPFKD_00913 2.8e-205 napA P Sodium/hydrogen exchanger family
COFIPFKD_00914 0.0 cadA P P-type ATPase
COFIPFKD_00915 1.5e-80 ykuL S (CBS) domain
COFIPFKD_00916 1e-207 ywhK S Membrane
COFIPFKD_00917 4.1e-44
COFIPFKD_00918 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
COFIPFKD_00919 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COFIPFKD_00920 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
COFIPFKD_00921 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COFIPFKD_00922 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COFIPFKD_00923 7.6e-177 pbpX2 V Beta-lactamase
COFIPFKD_00924 2.3e-133 S Protein of unknown function (DUF975)
COFIPFKD_00925 7.8e-137 lysA2 M Glycosyl hydrolases family 25
COFIPFKD_00926 7.9e-291 ytgP S Polysaccharide biosynthesis protein
COFIPFKD_00927 1.9e-36
COFIPFKD_00928 0.0 XK27_06780 V ABC transporter permease
COFIPFKD_00929 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
COFIPFKD_00930 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COFIPFKD_00931 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
COFIPFKD_00932 0.0 clpE O AAA domain (Cdc48 subfamily)
COFIPFKD_00933 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COFIPFKD_00934 9.7e-234 cycA E Amino acid permease
COFIPFKD_00935 9.2e-248 yifK E Amino acid permease
COFIPFKD_00936 1.9e-134 S PFAM Archaeal ATPase
COFIPFKD_00937 2.4e-172 V HNH endonuclease
COFIPFKD_00939 2.2e-139 puuD S peptidase C26
COFIPFKD_00940 1.8e-230 steT_1 E amino acid
COFIPFKD_00941 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
COFIPFKD_00942 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
COFIPFKD_00945 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COFIPFKD_00946 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COFIPFKD_00947 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COFIPFKD_00948 3.2e-74 L Transposase
COFIPFKD_00949 2.1e-78 2.7.13.3 T GHKL domain
COFIPFKD_00950 2.9e-79 K LytTr DNA-binding domain
COFIPFKD_00951 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
COFIPFKD_00952 5.7e-43 2.4.1.33 V HlyD family secretion protein
COFIPFKD_00954 1e-20 S Enterocin A Immunity
COFIPFKD_00955 2.4e-161 L An automated process has identified a potential problem with this gene model
COFIPFKD_00956 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
COFIPFKD_00957 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
COFIPFKD_00958 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
COFIPFKD_00959 1.7e-284 E Amino acid permease
COFIPFKD_00960 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
COFIPFKD_00961 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
COFIPFKD_00962 1.4e-115 mmuP E amino acid
COFIPFKD_00963 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
COFIPFKD_00964 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COFIPFKD_00965 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COFIPFKD_00966 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
COFIPFKD_00967 6.6e-67 L Helix-turn-helix domain
COFIPFKD_00968 7.4e-36 L Transposase
COFIPFKD_00969 1.4e-98 L Helix-turn-helix domain
COFIPFKD_00970 4.4e-118 L hmm pf00665
COFIPFKD_00972 1.6e-25 K Helix-turn-helix XRE-family like proteins
COFIPFKD_00973 1.2e-11
COFIPFKD_00974 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
COFIPFKD_00975 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COFIPFKD_00976 2e-264 lctP C L-lactate permease
COFIPFKD_00977 5e-129 znuB U ABC 3 transport family
COFIPFKD_00978 1.6e-117 fhuC P ABC transporter
COFIPFKD_00979 1.4e-148 psaA P Belongs to the bacterial solute-binding protein 9 family
COFIPFKD_00980 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
COFIPFKD_00981 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
COFIPFKD_00982 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
COFIPFKD_00983 1.8e-136 fruR K DeoR C terminal sensor domain
COFIPFKD_00984 1.8e-218 natB CP ABC-2 family transporter protein
COFIPFKD_00985 1.1e-164 natA S ABC transporter, ATP-binding protein
COFIPFKD_00986 1.7e-67
COFIPFKD_00987 2e-23
COFIPFKD_00988 8.2e-31 yozG K Transcriptional regulator
COFIPFKD_00989 3.7e-83
COFIPFKD_00990 3e-21
COFIPFKD_00994 2.2e-129 blpT
COFIPFKD_00995 1.4e-107 M Transport protein ComB
COFIPFKD_00996 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
COFIPFKD_00997 5.7e-272 P Sodium:sulfate symporter transmembrane region
COFIPFKD_00998 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
COFIPFKD_00999 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
COFIPFKD_01000 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COFIPFKD_01001 1.9e-261 frdC 1.3.5.4 C FAD binding domain
COFIPFKD_01002 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COFIPFKD_01003 3.4e-73 metI P ABC transporter permease
COFIPFKD_01004 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COFIPFKD_01005 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
COFIPFKD_01006 2.4e-175 F DNA/RNA non-specific endonuclease
COFIPFKD_01007 0.0 aha1 P E1-E2 ATPase
COFIPFKD_01008 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COFIPFKD_01009 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COFIPFKD_01010 1.2e-250 yifK E Amino acid permease
COFIPFKD_01011 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
COFIPFKD_01012 5.9e-45
COFIPFKD_01013 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COFIPFKD_01015 2.1e-45 S PFAM Archaeal ATPase
COFIPFKD_01016 7.3e-74
COFIPFKD_01017 0.0 kup P Transport of potassium into the cell
COFIPFKD_01018 0.0 pepO 3.4.24.71 O Peptidase family M13
COFIPFKD_01019 1.4e-210 yttB EGP Major facilitator Superfamily
COFIPFKD_01020 1.5e-230 XK27_04775 S PAS domain
COFIPFKD_01021 6.2e-103 S Iron-sulfur cluster assembly protein
COFIPFKD_01022 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COFIPFKD_01023 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
COFIPFKD_01024 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
COFIPFKD_01025 0.0 asnB 6.3.5.4 E Asparagine synthase
COFIPFKD_01026 1.6e-271 S Calcineurin-like phosphoesterase
COFIPFKD_01027 3.9e-84
COFIPFKD_01028 1.6e-105 tag 3.2.2.20 L glycosylase
COFIPFKD_01029 1.7e-174 L COG3385 FOG Transposase and inactivated derivatives
COFIPFKD_01030 2.7e-51
COFIPFKD_01031 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
COFIPFKD_01032 3.3e-44
COFIPFKD_01033 5.4e-183 S AAA domain
COFIPFKD_01034 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COFIPFKD_01035 1.4e-23
COFIPFKD_01036 7.3e-161 czcD P cation diffusion facilitator family transporter
COFIPFKD_01037 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
COFIPFKD_01038 6e-132 S membrane transporter protein
COFIPFKD_01039 1.9e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COFIPFKD_01040 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
COFIPFKD_01041 1.2e-49 S Protein of unknown function (DUF3021)
COFIPFKD_01042 2.8e-65 K LytTr DNA-binding domain
COFIPFKD_01043 1.2e-10
COFIPFKD_01044 2.6e-56 K Acetyltransferase (GNAT) domain
COFIPFKD_01045 1.9e-12 L Transposase
COFIPFKD_01046 1.4e-16 L Transposase
COFIPFKD_01047 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
COFIPFKD_01048 5.2e-68 L haloacid dehalogenase-like hydrolase
COFIPFKD_01049 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
COFIPFKD_01050 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
COFIPFKD_01051 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
COFIPFKD_01052 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
COFIPFKD_01053 5.3e-233 ulaA S PTS system sugar-specific permease component
COFIPFKD_01054 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COFIPFKD_01055 8.1e-175 ulaG S Beta-lactamase superfamily domain
COFIPFKD_01056 2.9e-190 yagE E Amino acid permease
COFIPFKD_01057 1.9e-86 3.4.21.96 S SLAP domain
COFIPFKD_01058 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COFIPFKD_01059 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COFIPFKD_01060 1.2e-107 hlyIII S protein, hemolysin III
COFIPFKD_01061 5.7e-147 DegV S Uncharacterised protein, DegV family COG1307
COFIPFKD_01062 7.1e-36 yozE S Belongs to the UPF0346 family
COFIPFKD_01063 1.1e-66 yjcE P NhaP-type Na H and K H
COFIPFKD_01064 1.5e-40 yjcE P Sodium proton antiporter
COFIPFKD_01065 1.9e-94 yjcE P Sodium proton antiporter
COFIPFKD_01066 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COFIPFKD_01067 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COFIPFKD_01068 5.8e-152 dprA LU DNA protecting protein DprA
COFIPFKD_01069 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COFIPFKD_01070 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
COFIPFKD_01071 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
COFIPFKD_01072 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
COFIPFKD_01073 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
COFIPFKD_01074 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
COFIPFKD_01075 1.4e-86 C Aldo keto reductase
COFIPFKD_01076 3.8e-48 M LysM domain protein
COFIPFKD_01077 2.9e-15 M LysM domain protein
COFIPFKD_01078 2.7e-26 L hmm pf00665
COFIPFKD_01079 1.8e-163
COFIPFKD_01080 7.8e-26 K Acetyltransferase (GNAT) domain
COFIPFKD_01082 0.0 ydgH S MMPL family
COFIPFKD_01083 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
COFIPFKD_01084 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
COFIPFKD_01085 1.8e-154 corA P CorA-like Mg2+ transporter protein
COFIPFKD_01086 2.3e-240 G Bacterial extracellular solute-binding protein
COFIPFKD_01087 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
COFIPFKD_01088 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
COFIPFKD_01089 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
COFIPFKD_01090 1.9e-203 malK P ATPases associated with a variety of cellular activities
COFIPFKD_01091 1.3e-281 pipD E Dipeptidase
COFIPFKD_01092 1.9e-158 endA F DNA RNA non-specific endonuclease
COFIPFKD_01093 8e-182 dnaQ 2.7.7.7 L EXOIII
COFIPFKD_01094 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
COFIPFKD_01095 3e-116 yviA S Protein of unknown function (DUF421)
COFIPFKD_01096 1.1e-56 S Protein of unknown function (DUF3290)
COFIPFKD_01097 2.8e-14 L PFAM transposase, IS4 family protein
COFIPFKD_01098 2.7e-36 yyaR K Acetyltransferase (GNAT) domain
COFIPFKD_01099 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COFIPFKD_01100 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
COFIPFKD_01101 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COFIPFKD_01102 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
COFIPFKD_01103 8.6e-199 tnpB L Putative transposase DNA-binding domain
COFIPFKD_01104 4.2e-84 yqeG S HAD phosphatase, family IIIA
COFIPFKD_01105 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
COFIPFKD_01106 2.2e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COFIPFKD_01107 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
COFIPFKD_01108 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COFIPFKD_01109 4.6e-216 ylbM S Belongs to the UPF0348 family
COFIPFKD_01110 4.7e-97 yceD S Uncharacterized ACR, COG1399
COFIPFKD_01111 1.2e-126 K response regulator
COFIPFKD_01112 2.2e-277 arlS 2.7.13.3 T Histidine kinase
COFIPFKD_01113 1e-12
COFIPFKD_01114 1.5e-97 S CAAX protease self-immunity
COFIPFKD_01115 6.1e-224 S SLAP domain
COFIPFKD_01116 5.7e-83 S Aminoacyl-tRNA editing domain
COFIPFKD_01117 2.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COFIPFKD_01118 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
COFIPFKD_01119 2.2e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COFIPFKD_01120 4.5e-58 yodB K Transcriptional regulator, HxlR family
COFIPFKD_01122 8.3e-24 papP P ABC transporter, permease protein
COFIPFKD_01123 1.1e-76 papP P ABC transporter, permease protein
COFIPFKD_01124 5.3e-116 P ABC transporter permease
COFIPFKD_01125 2.5e-107 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COFIPFKD_01126 1e-156 cjaA ET ABC transporter substrate-binding protein
COFIPFKD_01127 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COFIPFKD_01128 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COFIPFKD_01129 2e-61 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COFIPFKD_01130 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
COFIPFKD_01131 3.5e-157 metQ1 P Belongs to the nlpA lipoprotein family
COFIPFKD_01132 1.9e-25
COFIPFKD_01133 0.0 mco Q Multicopper oxidase
COFIPFKD_01134 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
COFIPFKD_01135 0.0 oppA E ABC transporter
COFIPFKD_01136 8.4e-229 Q Imidazolonepropionase and related amidohydrolases
COFIPFKD_01137 2.7e-246 3.5.1.47 S Peptidase dimerisation domain
COFIPFKD_01138 1e-137 S Protein of unknown function (DUF3100)
COFIPFKD_01139 9.7e-83 S An automated process has identified a potential problem with this gene model
COFIPFKD_01140 1.4e-52 EGP Sugar (and other) transporter
COFIPFKD_01141 1e-104
COFIPFKD_01142 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
COFIPFKD_01143 0.0 copA 3.6.3.54 P P-type ATPase
COFIPFKD_01144 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COFIPFKD_01145 4.9e-58 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COFIPFKD_01146 2.4e-36
COFIPFKD_01149 3.7e-20
COFIPFKD_01150 1.1e-139
COFIPFKD_01151 3.7e-261 V ABC transporter transmembrane region
COFIPFKD_01152 1.4e-37 S Putative adhesin
COFIPFKD_01153 6.7e-215 L Transposase
COFIPFKD_01154 2.5e-226 pbuG S permease
COFIPFKD_01155 9.7e-146 S haloacid dehalogenase-like hydrolase
COFIPFKD_01156 2e-225 S cog cog1373
COFIPFKD_01157 6.1e-61 K Transcriptional regulator
COFIPFKD_01158 1.3e-94 K Transcriptional regulator
COFIPFKD_01159 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
COFIPFKD_01160 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
COFIPFKD_01161 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
COFIPFKD_01162 2.8e-290
COFIPFKD_01164 2.1e-188 cggR K Putative sugar-binding domain
COFIPFKD_01165 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COFIPFKD_01166 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
COFIPFKD_01167 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COFIPFKD_01168 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
COFIPFKD_01169 1.2e-94
COFIPFKD_01170 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
COFIPFKD_01171 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COFIPFKD_01172 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
COFIPFKD_01173 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
COFIPFKD_01174 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
COFIPFKD_01175 2e-163 murB 1.3.1.98 M Cell wall formation
COFIPFKD_01176 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COFIPFKD_01177 1.3e-129 potB P ABC transporter permease
COFIPFKD_01178 4.8e-127 potC P ABC transporter permease
COFIPFKD_01179 7.3e-208 potD P ABC transporter
COFIPFKD_01180 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COFIPFKD_01181 2e-172 ybbR S YbbR-like protein
COFIPFKD_01182 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COFIPFKD_01183 1.4e-147 S hydrolase
COFIPFKD_01184 1.8e-75 K Penicillinase repressor
COFIPFKD_01185 1.6e-118
COFIPFKD_01186 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COFIPFKD_01187 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COFIPFKD_01188 8.3e-143 licT K CAT RNA binding domain
COFIPFKD_01189 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
COFIPFKD_01190 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COFIPFKD_01191 1e-149 D Alpha beta
COFIPFKD_01192 1.2e-92 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
COFIPFKD_01193 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
COFIPFKD_01194 5.2e-112 ica2 GT2 M Glycosyl transferase family group 2
COFIPFKD_01195 8.2e-36
COFIPFKD_01196 2.2e-90 2.7.7.65 T GGDEF domain
COFIPFKD_01197 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COFIPFKD_01199 2e-310 E Amino acid permease
COFIPFKD_01200 5.8e-100 L Helix-turn-helix domain
COFIPFKD_01201 1.3e-160 L hmm pf00665
COFIPFKD_01203 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COFIPFKD_01204 3.5e-101 ylbE GM NAD(P)H-binding
COFIPFKD_01205 7.6e-94 S VanZ like family
COFIPFKD_01206 8.9e-133 yebC K Transcriptional regulatory protein
COFIPFKD_01207 1.7e-179 comGA NU Type II IV secretion system protein
COFIPFKD_01208 1.7e-171 comGB NU type II secretion system
COFIPFKD_01209 3.1e-43 comGC U competence protein ComGC
COFIPFKD_01210 1.8e-69
COFIPFKD_01211 2.3e-41
COFIPFKD_01212 3.8e-77 comGF U Putative Competence protein ComGF
COFIPFKD_01213 1.6e-21
COFIPFKD_01214 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
COFIPFKD_01215 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COFIPFKD_01217 2.5e-89 M Protein of unknown function (DUF3737)
COFIPFKD_01218 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
COFIPFKD_01219 3.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
COFIPFKD_01220 7.7e-67 S SdpI/YhfL protein family
COFIPFKD_01221 4.4e-129 K Transcriptional regulatory protein, C terminal
COFIPFKD_01222 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
COFIPFKD_01223 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COFIPFKD_01224 3.8e-105 vanZ V VanZ like family
COFIPFKD_01225 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
COFIPFKD_01226 1.9e-153 EGP Major facilitator Superfamily
COFIPFKD_01227 5.5e-139 L COG2963 Transposase and inactivated derivatives
COFIPFKD_01228 1.1e-59 L COG2963 Transposase and inactivated derivatives
COFIPFKD_01229 1.2e-188 K Periplasmic binding protein-like domain
COFIPFKD_01230 2e-106 K Transcriptional regulator, AbiEi antitoxin
COFIPFKD_01231 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
COFIPFKD_01232 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COFIPFKD_01233 2.1e-142 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
COFIPFKD_01234 9.3e-80 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
COFIPFKD_01235 7.2e-221 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
COFIPFKD_01236 5.4e-165 lacR K Transcriptional regulator
COFIPFKD_01237 8.9e-207 lacS G Transporter
COFIPFKD_01238 2.6e-103 lacS G Transporter
COFIPFKD_01239 0.0 lacZ 3.2.1.23 G -beta-galactosidase
COFIPFKD_01240 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COFIPFKD_01241 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
COFIPFKD_01242 1.2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
COFIPFKD_01243 3.3e-131 S Protein of unknown function (DUF805)
COFIPFKD_01244 6.4e-159 L HNH nucleases
COFIPFKD_01245 1e-119 yfbR S HD containing hydrolase-like enzyme
COFIPFKD_01246 4e-177 G Glycosyl hydrolases family 8
COFIPFKD_01247 4.5e-189 ydaM M Glycosyl transferase
COFIPFKD_01248 1.1e-07 S Uncharacterised protein family (UPF0236)
COFIPFKD_01249 1.2e-17
COFIPFKD_01250 1.9e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
COFIPFKD_01251 2e-70 S Iron-sulphur cluster biosynthesis
COFIPFKD_01252 7.5e-192 ybiR P Citrate transporter
COFIPFKD_01253 5.1e-96 lemA S LemA family
COFIPFKD_01254 8.3e-157 htpX O Belongs to the peptidase M48B family
COFIPFKD_01255 7.9e-174 K helix_turn_helix, arabinose operon control protein
COFIPFKD_01256 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
COFIPFKD_01257 1.3e-77 P Cobalt transport protein
COFIPFKD_01258 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
COFIPFKD_01259 2.9e-47 L Transposase
COFIPFKD_01260 1.7e-145 L An automated process has identified a potential problem with this gene model
COFIPFKD_01261 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COFIPFKD_01263 1.4e-34
COFIPFKD_01264 3.6e-63
COFIPFKD_01267 4.9e-118
COFIPFKD_01268 3.8e-104 pncA Q Isochorismatase family
COFIPFKD_01270 2e-35
COFIPFKD_01271 0.0 snf 2.7.11.1 KL domain protein
COFIPFKD_01272 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COFIPFKD_01273 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COFIPFKD_01274 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COFIPFKD_01275 5.6e-183 K Transcriptional regulator
COFIPFKD_01276 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
COFIPFKD_01277 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COFIPFKD_01278 4e-57 K Helix-turn-helix domain
COFIPFKD_01279 5.7e-18
COFIPFKD_01280 1.5e-239 G Bacterial extracellular solute-binding protein
COFIPFKD_01281 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
COFIPFKD_01282 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
COFIPFKD_01284 0.0 S SLAP domain
COFIPFKD_01285 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
COFIPFKD_01286 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
COFIPFKD_01287 3.4e-42 S RloB-like protein
COFIPFKD_01288 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
COFIPFKD_01289 2.3e-51 3.1.21.3 V Type I restriction modification DNA specificity domain
COFIPFKD_01290 8.3e-45 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
COFIPFKD_01291 1.2e-63 S SIR2-like domain
COFIPFKD_01292 3.2e-10 S Domain of unknown function DUF87
COFIPFKD_01293 3.4e-27
COFIPFKD_01294 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
COFIPFKD_01295 5.4e-53 hipB K sequence-specific DNA binding
COFIPFKD_01296 4.8e-42 S SnoaL-like domain
COFIPFKD_01297 0.0 L PLD-like domain
COFIPFKD_01298 1.3e-226 L Transposase
COFIPFKD_01299 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
COFIPFKD_01300 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
COFIPFKD_01301 2.6e-280 thrC 4.2.3.1 E Threonine synthase
COFIPFKD_01302 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
COFIPFKD_01303 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COFIPFKD_01304 3.6e-117
COFIPFKD_01305 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COFIPFKD_01307 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COFIPFKD_01308 1.3e-116 S Peptidase family M23
COFIPFKD_01309 1.4e-83 K FR47-like protein
COFIPFKD_01310 1.6e-08
COFIPFKD_01311 1.6e-08
COFIPFKD_01312 1.6e-08
COFIPFKD_01314 1.3e-81 yebR 1.8.4.14 T GAF domain-containing protein
COFIPFKD_01315 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COFIPFKD_01316 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COFIPFKD_01317 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COFIPFKD_01318 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
COFIPFKD_01319 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COFIPFKD_01320 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COFIPFKD_01321 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COFIPFKD_01322 1.6e-35 S cog cog0433
COFIPFKD_01323 1.9e-110 F DNA/RNA non-specific endonuclease
COFIPFKD_01324 2.7e-34 S YSIRK type signal peptide
COFIPFKD_01326 5.5e-53
COFIPFKD_01327 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
COFIPFKD_01328 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COFIPFKD_01329 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COFIPFKD_01330 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COFIPFKD_01331 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
COFIPFKD_01332 0.0 FbpA K Fibronectin-binding protein
COFIPFKD_01333 1.1e-66
COFIPFKD_01334 1.3e-159 degV S EDD domain protein, DegV family
COFIPFKD_01335 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
COFIPFKD_01336 1.2e-100 treR K UTRA
COFIPFKD_01337 3.3e-283 treB G phosphotransferase system
COFIPFKD_01338 8.2e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COFIPFKD_01339 1.9e-191 yrvN L AAA C-terminal domain
COFIPFKD_01340 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COFIPFKD_01341 9e-83 K Acetyltransferase (GNAT) domain
COFIPFKD_01342 1.3e-229 S Putative peptidoglycan binding domain
COFIPFKD_01343 7.5e-95 S ECF-type riboflavin transporter, S component
COFIPFKD_01344 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
COFIPFKD_01345 9.3e-204 pbpX1 V Beta-lactamase
COFIPFKD_01346 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
COFIPFKD_01347 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COFIPFKD_01348 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
COFIPFKD_01350 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
COFIPFKD_01351 4.3e-298 S Predicted membrane protein (DUF2207)
COFIPFKD_01352 2.8e-157 cinI S Serine hydrolase (FSH1)
COFIPFKD_01353 1e-205 M Glycosyl hydrolases family 25
COFIPFKD_01355 8.5e-178 I Carboxylesterase family
COFIPFKD_01356 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
COFIPFKD_01357 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
COFIPFKD_01358 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
COFIPFKD_01359 7.5e-132 S haloacid dehalogenase-like hydrolase
COFIPFKD_01360 7e-50
COFIPFKD_01361 1.9e-37
COFIPFKD_01362 1.2e-63 S Alpha beta hydrolase
COFIPFKD_01363 1e-23 S Alpha beta hydrolase
COFIPFKD_01364 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COFIPFKD_01365 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
COFIPFKD_01366 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COFIPFKD_01367 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COFIPFKD_01368 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
COFIPFKD_01369 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COFIPFKD_01370 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COFIPFKD_01371 1.2e-94 sigH K Belongs to the sigma-70 factor family
COFIPFKD_01372 1.7e-34
COFIPFKD_01373 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
COFIPFKD_01374 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COFIPFKD_01375 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COFIPFKD_01376 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
COFIPFKD_01377 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COFIPFKD_01378 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COFIPFKD_01379 2.8e-157 pstS P Phosphate
COFIPFKD_01380 2.6e-162 pstC P probably responsible for the translocation of the substrate across the membrane
COFIPFKD_01381 3.4e-79
COFIPFKD_01382 1e-242 cpdA S Calcineurin-like phosphoesterase
COFIPFKD_01383 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
COFIPFKD_01384 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COFIPFKD_01385 1e-107 ypsA S Belongs to the UPF0398 family
COFIPFKD_01386 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COFIPFKD_01387 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
COFIPFKD_01388 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COFIPFKD_01389 1.3e-114 dnaD L DnaD domain protein
COFIPFKD_01390 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
COFIPFKD_01391 9.2e-89 ypmB S Protein conserved in bacteria
COFIPFKD_01392 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
COFIPFKD_01393 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
COFIPFKD_01394 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COFIPFKD_01395 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
COFIPFKD_01396 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
COFIPFKD_01397 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
COFIPFKD_01398 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COFIPFKD_01399 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
COFIPFKD_01400 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
COFIPFKD_01401 9.7e-169
COFIPFKD_01402 7.5e-143
COFIPFKD_01403 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COFIPFKD_01404 1.4e-26
COFIPFKD_01405 9.6e-144
COFIPFKD_01406 5.1e-137
COFIPFKD_01407 4.5e-141
COFIPFKD_01408 9.6e-124 skfE V ATPases associated with a variety of cellular activities
COFIPFKD_01409 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
COFIPFKD_01410 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COFIPFKD_01411 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COFIPFKD_01412 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
COFIPFKD_01413 4.8e-81 mutT 3.6.1.55 F NUDIX domain
COFIPFKD_01414 1.4e-127 S Peptidase family M23
COFIPFKD_01415 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COFIPFKD_01416 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COFIPFKD_01417 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
COFIPFKD_01418 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
COFIPFKD_01419 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
COFIPFKD_01420 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COFIPFKD_01421 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COFIPFKD_01422 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
COFIPFKD_01423 3.5e-71 yqeY S YqeY-like protein
COFIPFKD_01424 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
COFIPFKD_01425 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
COFIPFKD_01426 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
COFIPFKD_01427 2.2e-218 L Transposase
COFIPFKD_01429 4.6e-88 ymdB S Macro domain protein
COFIPFKD_01430 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COFIPFKD_01431 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
COFIPFKD_01432 1e-167 cvfB S S1 domain
COFIPFKD_01433 2.9e-165 xerD D recombinase XerD
COFIPFKD_01434 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COFIPFKD_01435 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COFIPFKD_01436 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COFIPFKD_01437 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COFIPFKD_01438 5.7e-113 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COFIPFKD_01439 2.7e-18 M Lysin motif
COFIPFKD_01440 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
COFIPFKD_01441 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
COFIPFKD_01442 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
COFIPFKD_01443 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COFIPFKD_01444 1.4e-75 S Tetratricopeptide repeat protein
COFIPFKD_01445 3.8e-99 S Tetratricopeptide repeat protein
COFIPFKD_01446 2e-36 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COFIPFKD_01447 2e-166 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COFIPFKD_01448 5e-230 ybgG 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
COFIPFKD_01449 1.4e-137 licR 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
COFIPFKD_01450 0.0 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
COFIPFKD_01451 1.1e-66 L Transposase and inactivated derivatives, IS30 family
COFIPFKD_01452 1.1e-115 L Transposase and inactivated derivatives, IS30 family
COFIPFKD_01453 1.3e-71 K Helix-turn-helix domain, rpiR family
COFIPFKD_01454 4.1e-21 K Helix-turn-helix domain, rpiR family
COFIPFKD_01455 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
COFIPFKD_01456 2.5e-204 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COFIPFKD_01458 1.8e-104 3.2.2.20 K acetyltransferase
COFIPFKD_01459 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COFIPFKD_01460 1e-53 S PAS domain
COFIPFKD_01461 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
COFIPFKD_01462 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
COFIPFKD_01463 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
COFIPFKD_01464 3.1e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
COFIPFKD_01465 3e-209 msmX P Belongs to the ABC transporter superfamily
COFIPFKD_01466 2.8e-211 malE G Bacterial extracellular solute-binding protein
COFIPFKD_01467 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
COFIPFKD_01468 3.3e-147 malG P ABC transporter permease
COFIPFKD_01469 4.3e-67 K Helix-turn-helix XRE-family like proteins
COFIPFKD_01472 4.8e-28
COFIPFKD_01473 3.4e-129 S (CBS) domain
COFIPFKD_01474 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COFIPFKD_01475 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COFIPFKD_01476 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COFIPFKD_01477 1.6e-33 yabO J S4 domain protein
COFIPFKD_01478 6.8e-60 divIC D Septum formation initiator
COFIPFKD_01479 1.8e-62 yabR J S1 RNA binding domain
COFIPFKD_01480 1.5e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COFIPFKD_01481 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COFIPFKD_01482 1.1e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COFIPFKD_01483 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COFIPFKD_01484 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COFIPFKD_01485 1.9e-166 repA S Replication initiator protein A
COFIPFKD_01486 3.4e-135 S Fic/DOC family
COFIPFKD_01487 1e-190 L Transposase and inactivated derivatives, IS30 family
COFIPFKD_01491 1.9e-19 L Replication initiation factor
COFIPFKD_01492 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COFIPFKD_01493 9.3e-74 nrdI F NrdI Flavodoxin like
COFIPFKD_01494 3.6e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COFIPFKD_01495 1.1e-109 tnpR1 L Resolvase, N terminal domain
COFIPFKD_01496 4.7e-70 L IS1381, transposase OrfA
COFIPFKD_01497 1.1e-76 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COFIPFKD_01498 1.3e-28
COFIPFKD_01499 1.7e-142 soj D AAA domain
COFIPFKD_01500 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
COFIPFKD_01501 2.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
COFIPFKD_01502 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COFIPFKD_01503 3.6e-163 yihY S Belongs to the UPF0761 family
COFIPFKD_01504 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
COFIPFKD_01505 4.1e-80 fld C Flavodoxin
COFIPFKD_01506 7e-87 gtcA S Teichoic acid glycosylation protein
COFIPFKD_01507 1.5e-234 L Transposase DDE domain
COFIPFKD_01508 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COFIPFKD_01510 1e-248 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COFIPFKD_01511 1.1e-210 yfmL 3.6.4.13 L DEAD DEAH box helicase
COFIPFKD_01512 1.3e-61 M Glycosyl hydrolases family 25
COFIPFKD_01513 2.6e-61 M Glycosyl hydrolases family 25
COFIPFKD_01514 1.3e-141 yfeO P Voltage gated chloride channel
COFIPFKD_01515 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
COFIPFKD_01516 1.4e-51
COFIPFKD_01517 2.1e-42
COFIPFKD_01518 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COFIPFKD_01519 9.5e-297 ybeC E amino acid
COFIPFKD_01520 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
COFIPFKD_01521 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
COFIPFKD_01522 2.5e-39 rpmE2 J Ribosomal protein L31
COFIPFKD_01523 8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COFIPFKD_01524 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COFIPFKD_01525 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COFIPFKD_01526 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COFIPFKD_01527 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COFIPFKD_01528 9.5e-31
COFIPFKD_01529 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COFIPFKD_01530 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COFIPFKD_01531 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COFIPFKD_01532 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COFIPFKD_01533 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COFIPFKD_01534 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
COFIPFKD_01535 5.9e-199 L Transposase and inactivated derivatives, IS30 family
COFIPFKD_01536 9.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COFIPFKD_01537 1.5e-182 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COFIPFKD_01538 2.9e-277 V ABC transporter transmembrane region
COFIPFKD_01539 7.9e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
COFIPFKD_01540 3.1e-130 T Transcriptional regulatory protein, C terminal
COFIPFKD_01541 5.2e-187 T GHKL domain
COFIPFKD_01542 3.4e-76 S Peptidase propeptide and YPEB domain
COFIPFKD_01543 2.5e-72 S Peptidase propeptide and YPEB domain
COFIPFKD_01544 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
COFIPFKD_01545 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
COFIPFKD_01546 7e-68 V ABC transporter transmembrane region
COFIPFKD_01547 9e-161 V ABC transporter transmembrane region
COFIPFKD_01548 2.3e-309 oppA3 E ABC transporter, substratebinding protein
COFIPFKD_01549 2.4e-60 ypaA S Protein of unknown function (DUF1304)
COFIPFKD_01550 2.1e-28 S Peptidase propeptide and YPEB domain
COFIPFKD_01551 7.1e-237 L transposase, IS605 OrfB family
COFIPFKD_01552 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COFIPFKD_01553 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COFIPFKD_01554 4.1e-90 S Short repeat of unknown function (DUF308)
COFIPFKD_01555 6.2e-165 rapZ S Displays ATPase and GTPase activities
COFIPFKD_01556 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
COFIPFKD_01557 2.1e-171 whiA K May be required for sporulation
COFIPFKD_01558 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COFIPFKD_01559 0.0 S SH3-like domain
COFIPFKD_01560 4.9e-111 ybbL S ABC transporter, ATP-binding protein
COFIPFKD_01561 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
COFIPFKD_01562 6e-73 L Transposase
COFIPFKD_01563 0.0 dnaE 2.7.7.7 L DNA polymerase
COFIPFKD_01564 2.3e-23 S Protein of unknown function (DUF2929)
COFIPFKD_01565 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
COFIPFKD_01566 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
COFIPFKD_01567 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
COFIPFKD_01568 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COFIPFKD_01569 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COFIPFKD_01570 2.2e-292 I Acyltransferase
COFIPFKD_01571 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COFIPFKD_01572 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COFIPFKD_01573 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
COFIPFKD_01574 1.1e-243 yfnA E Amino Acid
COFIPFKD_01575 1.2e-154 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COFIPFKD_01576 1.3e-148 yxeH S hydrolase
COFIPFKD_01577 2.7e-32 S reductase
COFIPFKD_01578 1.7e-38 S reductase
COFIPFKD_01579 4.8e-34 S reductase
COFIPFKD_01580 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COFIPFKD_01581 2.4e-176 L Transposase and inactivated derivatives, IS30 family
COFIPFKD_01582 8.3e-20 L Transposase
COFIPFKD_01583 1.2e-222 patA 2.6.1.1 E Aminotransferase
COFIPFKD_01584 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COFIPFKD_01585 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
COFIPFKD_01586 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COFIPFKD_01587 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COFIPFKD_01588 8.5e-60
COFIPFKD_01589 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
COFIPFKD_01590 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COFIPFKD_01591 5.9e-37 M domain protein
COFIPFKD_01593 6.2e-249 yjjP S Putative threonine/serine exporter
COFIPFKD_01594 2.6e-177 citR K Putative sugar-binding domain
COFIPFKD_01595 1.5e-50
COFIPFKD_01596 5.5e-09
COFIPFKD_01597 2.9e-66 S Domain of unknown function DUF1828
COFIPFKD_01598 4.8e-94 S UPF0397 protein
COFIPFKD_01599 0.0 ykoD P ABC transporter, ATP-binding protein
COFIPFKD_01600 3.6e-146 cbiQ P cobalt transport
COFIPFKD_01601 3.5e-21
COFIPFKD_01602 9.3e-72 yeaL S Protein of unknown function (DUF441)
COFIPFKD_01603 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
COFIPFKD_01604 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
COFIPFKD_01605 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
COFIPFKD_01606 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
COFIPFKD_01607 1.7e-153 ydjP I Alpha/beta hydrolase family
COFIPFKD_01608 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
COFIPFKD_01609 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
COFIPFKD_01610 1.6e-80
COFIPFKD_01611 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
COFIPFKD_01612 2.1e-39
COFIPFKD_01613 3.9e-119 C nitroreductase
COFIPFKD_01614 1.7e-249 yhdP S Transporter associated domain
COFIPFKD_01615 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COFIPFKD_01616 0.0 1.3.5.4 C FAD binding domain
COFIPFKD_01617 1.1e-87 L PFAM transposase, IS4 family protein
COFIPFKD_01618 1.2e-49 L PFAM transposase, IS4 family protein
COFIPFKD_01619 2.4e-212 1.3.5.4 C FAD binding domain
COFIPFKD_01620 3.4e-126 1.3.5.4 C FAD binding domain
COFIPFKD_01621 9e-121
COFIPFKD_01622 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
COFIPFKD_01623 1.6e-184 S Putative peptidoglycan binding domain
COFIPFKD_01624 4e-16
COFIPFKD_01625 7.9e-92 liaI S membrane
COFIPFKD_01626 6.6e-70 XK27_02470 K LytTr DNA-binding domain
COFIPFKD_01627 1.2e-18 S Sugar efflux transporter for intercellular exchange
COFIPFKD_01628 1.3e-250 dtpT U amino acid peptide transporter
COFIPFKD_01629 0.0 pepN 3.4.11.2 E aminopeptidase
COFIPFKD_01630 2.8e-47 lysM M LysM domain
COFIPFKD_01631 1.3e-174
COFIPFKD_01632 1.1e-151 mdtG EGP Major facilitator Superfamily
COFIPFKD_01633 6.9e-47 mdtG EGP Major facilitator Superfamily
COFIPFKD_01634 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COFIPFKD_01635 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COFIPFKD_01636 1.7e-29 secG U Preprotein translocase
COFIPFKD_01637 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COFIPFKD_01638 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COFIPFKD_01639 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
COFIPFKD_01640 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
COFIPFKD_01668 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
COFIPFKD_01669 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
COFIPFKD_01670 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
COFIPFKD_01671 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
COFIPFKD_01672 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COFIPFKD_01673 7.5e-100 J Acetyltransferase (GNAT) domain
COFIPFKD_01674 1.4e-110 yjbF S SNARE associated Golgi protein
COFIPFKD_01675 2.7e-151 I alpha/beta hydrolase fold
COFIPFKD_01676 5.2e-156 hipB K Helix-turn-helix
COFIPFKD_01677 1.4e-15 S cog cog1373
COFIPFKD_01678 1e-30 S cog cog1373
COFIPFKD_01679 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
COFIPFKD_01680 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
COFIPFKD_01681 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
COFIPFKD_01682 6.8e-116 dedA S SNARE-like domain protein
COFIPFKD_01683 3.7e-100 S Protein of unknown function (DUF1461)
COFIPFKD_01684 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COFIPFKD_01685 2.1e-92 yutD S Protein of unknown function (DUF1027)
COFIPFKD_01686 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
COFIPFKD_01687 4.3e-55
COFIPFKD_01688 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COFIPFKD_01689 3.2e-181 ccpA K catabolite control protein A
COFIPFKD_01690 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COFIPFKD_01691 1.3e-36
COFIPFKD_01692 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COFIPFKD_01693 3.7e-146 ykuT M mechanosensitive ion channel
COFIPFKD_01694 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COFIPFKD_01695 3.3e-151 htrA 3.4.21.107 O serine protease
COFIPFKD_01696 4.1e-147 vicX 3.1.26.11 S domain protein
COFIPFKD_01697 3.4e-149 yycI S YycH protein
COFIPFKD_01698 3.3e-258 yycH S YycH protein
COFIPFKD_01699 2.2e-305 vicK 2.7.13.3 T Histidine kinase
COFIPFKD_01700 4.8e-131 K response regulator
COFIPFKD_01702 4.9e-34
COFIPFKD_01704 4.2e-149 arbV 2.3.1.51 I Acyl-transferase
COFIPFKD_01705 1.5e-155 arbx M Glycosyl transferase family 8
COFIPFKD_01707 4.9e-31 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COFIPFKD_01708 9.4e-158 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COFIPFKD_01709 3.3e-275 yjeM E Amino Acid
COFIPFKD_01710 5.8e-83 S Fic/DOC family
COFIPFKD_01711 9.9e-180
COFIPFKD_01712 2.8e-100
COFIPFKD_01713 2.2e-78
COFIPFKD_01714 2.2e-85 S Protein of unknown function (DUF805)
COFIPFKD_01715 2.3e-69 O OsmC-like protein
COFIPFKD_01716 7.2e-209 EGP Major facilitator Superfamily
COFIPFKD_01717 2.6e-103 sptS 2.7.13.3 T Histidine kinase
COFIPFKD_01718 1.1e-103 sptS 2.7.13.3 T Histidine kinase
COFIPFKD_01719 3.2e-105 K response regulator
COFIPFKD_01720 3.4e-100 2.7.6.5 T Region found in RelA / SpoT proteins
COFIPFKD_01721 1e-48 S Metal binding domain of Ada
COFIPFKD_01722 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
COFIPFKD_01723 9e-137 lysR5 K LysR substrate binding domain
COFIPFKD_01724 8.8e-234 arcA 3.5.3.6 E Arginine
COFIPFKD_01725 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COFIPFKD_01726 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
COFIPFKD_01727 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
COFIPFKD_01728 2.3e-215 S Sterol carrier protein domain
COFIPFKD_01729 1e-20
COFIPFKD_01730 4.9e-108 K LysR substrate binding domain
COFIPFKD_01731 9e-98
COFIPFKD_01732 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
COFIPFKD_01733 8.3e-83 ybbH_2 K rpiR family
COFIPFKD_01734 3.4e-195 S Bacterial protein of unknown function (DUF871)
COFIPFKD_01735 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
COFIPFKD_01736 1.8e-119 S Putative esterase
COFIPFKD_01737 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
COFIPFKD_01738 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
COFIPFKD_01740 8.5e-260 qacA EGP Major facilitator Superfamily
COFIPFKD_01741 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COFIPFKD_01744 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
COFIPFKD_01747 1.6e-310 oppA E ABC transporter, substratebinding protein
COFIPFKD_01748 5e-301 oppA E ABC transporter, substratebinding protein
COFIPFKD_01749 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
COFIPFKD_01750 4.6e-257 pepC 3.4.22.40 E aminopeptidase
COFIPFKD_01752 3.4e-53
COFIPFKD_01753 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COFIPFKD_01754 8.4e-265 S Fibronectin type III domain
COFIPFKD_01755 2.2e-120 lsa S ABC transporter
COFIPFKD_01756 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COFIPFKD_01757 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
COFIPFKD_01758 6.3e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
COFIPFKD_01759 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COFIPFKD_01760 4e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COFIPFKD_01761 2.4e-10 L Psort location Cytoplasmic, score
COFIPFKD_01762 5.8e-13 L Transposase and inactivated derivatives, IS30 family
COFIPFKD_01763 1.5e-124 L Transposase and inactivated derivatives, IS30 family
COFIPFKD_01764 4.7e-182 pepA E M42 glutamyl aminopeptidase
COFIPFKD_01765 2.2e-311 ybiT S ABC transporter, ATP-binding protein
COFIPFKD_01766 5.9e-174 S Aldo keto reductase
COFIPFKD_01767 2.7e-138
COFIPFKD_01768 2.8e-202 steT E amino acid
COFIPFKD_01769 2.4e-26 steT E amino acid
COFIPFKD_01770 8.6e-243 steT E amino acid
COFIPFKD_01771 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
COFIPFKD_01772 1.9e-147 glnH ET ABC transporter
COFIPFKD_01773 1.4e-80 K Transcriptional regulator, MarR family
COFIPFKD_01774 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
COFIPFKD_01775 0.0 V ABC transporter transmembrane region
COFIPFKD_01776 1.6e-100 S ABC-type cobalt transport system, permease component
COFIPFKD_01777 1e-246 G MFS/sugar transport protein
COFIPFKD_01778 1e-44 udk 2.7.1.48 F Zeta toxin
COFIPFKD_01779 3.8e-46 udk 2.7.1.48 F Zeta toxin
COFIPFKD_01780 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COFIPFKD_01781 1.2e-146 glnH ET ABC transporter substrate-binding protein
COFIPFKD_01782 3.7e-90 gluC P ABC transporter permease
COFIPFKD_01783 4.7e-109 glnP P ABC transporter permease
COFIPFKD_01784 1.1e-164 S Protein of unknown function (DUF2974)
COFIPFKD_01785 2.6e-09
COFIPFKD_01786 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
COFIPFKD_01787 1.3e-235 G Bacterial extracellular solute-binding protein
COFIPFKD_01788 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
COFIPFKD_01789 3.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COFIPFKD_01790 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COFIPFKD_01791 0.0 kup P Transport of potassium into the cell
COFIPFKD_01792 9.1e-175 rihB 3.2.2.1 F Nucleoside
COFIPFKD_01793 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
COFIPFKD_01794 1.2e-154 S hydrolase
COFIPFKD_01795 2.5e-59 S Enterocin A Immunity
COFIPFKD_01796 3.1e-136 glcR K DeoR C terminal sensor domain
COFIPFKD_01797 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
COFIPFKD_01798 2e-160 rssA S Phospholipase, patatin family
COFIPFKD_01799 5.4e-147 S hydrolase
COFIPFKD_01800 0.0 clpE O Belongs to the ClpA ClpB family
COFIPFKD_01801 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
COFIPFKD_01802 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COFIPFKD_01803 1.4e-140 hlyX S Transporter associated domain
COFIPFKD_01804 2.7e-74
COFIPFKD_01805 1.6e-85
COFIPFKD_01806 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
COFIPFKD_01807 4.6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COFIPFKD_01808 1.4e-118 D Alpha beta
COFIPFKD_01809 8.8e-58 S Peptidase propeptide and YPEB domain
COFIPFKD_01810 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COFIPFKD_01811 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
COFIPFKD_01812 7.1e-98 E GDSL-like Lipase/Acylhydrolase
COFIPFKD_01813 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
COFIPFKD_01814 1.6e-143 aatB ET ABC transporter substrate-binding protein
COFIPFKD_01815 1e-105 glnQ 3.6.3.21 E ABC transporter
COFIPFKD_01816 1.5e-107 glnP P ABC transporter permease
COFIPFKD_01817 0.0 helD 3.6.4.12 L DNA helicase
COFIPFKD_01818 2.3e-116 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
COFIPFKD_01819 1.4e-126 pgm3 G Phosphoglycerate mutase family
COFIPFKD_01820 1.2e-241 S response to antibiotic
COFIPFKD_01821 4.9e-125
COFIPFKD_01822 0.0 3.6.3.8 P P-type ATPase
COFIPFKD_01823 8.7e-66 2.7.1.191 G PTS system fructose IIA component
COFIPFKD_01824 4.4e-43
COFIPFKD_01825 5.9e-09
COFIPFKD_01826 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
COFIPFKD_01827 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
COFIPFKD_01828 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
COFIPFKD_01829 4.2e-61 V Abi-like protein
COFIPFKD_01830 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
COFIPFKD_01834 2.7e-155 L Transposase
COFIPFKD_01835 3.8e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
COFIPFKD_01836 4.4e-151 S Metal-independent alpha-mannosidase (GH125)
COFIPFKD_01837 2e-234 mepA V MATE efflux family protein
COFIPFKD_01838 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
COFIPFKD_01839 1.8e-58 S Putative adhesin
COFIPFKD_01840 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COFIPFKD_01841 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
COFIPFKD_01842 1.1e-83 dps P Belongs to the Dps family
COFIPFKD_01843 2e-178 MA20_14895 S Conserved hypothetical protein 698
COFIPFKD_01845 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COFIPFKD_01846 3.9e-287 clcA P chloride
COFIPFKD_01847 4e-32 E Zn peptidase
COFIPFKD_01848 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
COFIPFKD_01849 1.2e-44
COFIPFKD_01850 9.1e-106 S Bacteriocin helveticin-J
COFIPFKD_01851 1.3e-117 S SLAP domain
COFIPFKD_01852 3.5e-136 S SLAP domain
COFIPFKD_01853 8e-210
COFIPFKD_01854 1.2e-18
COFIPFKD_01855 7.3e-175 EGP Sugar (and other) transporter
COFIPFKD_01856 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
COFIPFKD_01857 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
COFIPFKD_01858 6.7e-98 M ErfK YbiS YcfS YnhG
COFIPFKD_01859 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COFIPFKD_01860 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COFIPFKD_01862 4.7e-46 pspC KT PspC domain
COFIPFKD_01863 3.3e-237 L COG2963 Transposase and inactivated derivatives
COFIPFKD_01864 2.8e-140 sufC O FeS assembly ATPase SufC
COFIPFKD_01865 3.5e-174 sufD O FeS assembly protein SufD
COFIPFKD_01866 5.3e-178 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COFIPFKD_01867 2.4e-59 nifU C SUF system FeS assembly protein, NifU family
COFIPFKD_01868 2e-266 sufB O assembly protein SufB
COFIPFKD_01869 5.3e-45 yitW S Iron-sulfur cluster assembly protein
COFIPFKD_01870 2.9e-247 mntH P H( )-stimulated, divalent metal cation uptake system
COFIPFKD_01871 5.2e-08
COFIPFKD_01872 3.6e-90 ntd 2.4.2.6 F Nucleoside
COFIPFKD_01873 1.7e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COFIPFKD_01874 9.8e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
COFIPFKD_01875 8.8e-84 uspA T universal stress protein
COFIPFKD_01877 1.2e-161 phnD P Phosphonate ABC transporter
COFIPFKD_01878 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
COFIPFKD_01879 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
COFIPFKD_01880 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
COFIPFKD_01881 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
COFIPFKD_01883 4.2e-63 lmrB EGP Major facilitator Superfamily
COFIPFKD_01884 2.9e-122 rbtT P Major Facilitator Superfamily
COFIPFKD_01885 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
COFIPFKD_01886 2.5e-86 K GNAT family
COFIPFKD_01887 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
COFIPFKD_01889 4.3e-36
COFIPFKD_01890 6.2e-288 P ABC transporter
COFIPFKD_01891 2.3e-07 V ABC-type multidrug transport system, ATPase and permease components
COFIPFKD_01892 1.5e-25 S CAAX protease self-immunity
COFIPFKD_01893 1.4e-22 S CAAX protease self-immunity
COFIPFKD_01894 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
COFIPFKD_01896 1.6e-96 ybaT E Amino acid permease
COFIPFKD_01897 1.7e-07 S LPXTG cell wall anchor motif
COFIPFKD_01898 2.6e-146 S Putative ABC-transporter type IV
COFIPFKD_01900 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
COFIPFKD_01901 0.0 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
COFIPFKD_01902 5.2e-117 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COFIPFKD_01903 1.2e-232 oppA E ABC transporter substrate-binding protein
COFIPFKD_01904 8.6e-97 oppA E ABC transporter substrate-binding protein
COFIPFKD_01905 1.4e-176 K AI-2E family transporter
COFIPFKD_01906 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
COFIPFKD_01907 4.1e-18
COFIPFKD_01908 5.2e-248 G Major Facilitator
COFIPFKD_01909 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
COFIPFKD_01910 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
COFIPFKD_01911 1.7e-174 ABC-SBP S ABC transporter
COFIPFKD_01912 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COFIPFKD_01913 2e-155 P CorA-like Mg2+ transporter protein
COFIPFKD_01914 1.2e-160 yvgN C Aldo keto reductase
COFIPFKD_01915 0.0 tetP J elongation factor G
COFIPFKD_01916 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
COFIPFKD_01917 7.6e-134 EGP Major facilitator Superfamily
COFIPFKD_01918 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COFIPFKD_01921 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
COFIPFKD_01922 1.3e-273 E amino acid
COFIPFKD_01923 0.0 L Helicase C-terminal domain protein
COFIPFKD_01924 6.2e-205 pbpX1 V Beta-lactamase
COFIPFKD_01925 5.1e-226 N Uncharacterized conserved protein (DUF2075)
COFIPFKD_01926 1.2e-70 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
COFIPFKD_01927 1.9e-75 M LysM domain
COFIPFKD_01928 1.3e-42
COFIPFKD_01930 4.9e-35
COFIPFKD_01931 4.5e-76 yniG EGP Major facilitator Superfamily
COFIPFKD_01932 5.4e-237 L transposase, IS605 OrfB family
COFIPFKD_01933 1.4e-109 yniG EGP Major facilitator Superfamily
COFIPFKD_01934 2.4e-128 S cog cog1373
COFIPFKD_01935 2.3e-72 L Transposase
COFIPFKD_01936 2.4e-91 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
COFIPFKD_01937 1.8e-132 infB M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
COFIPFKD_01938 2.3e-101 L An automated process has identified a potential problem with this gene model
COFIPFKD_01939 4.6e-25 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
COFIPFKD_01940 4e-60 L Resolvase, N terminal domain
COFIPFKD_01941 5.8e-211 M Glycosyl hydrolases family 25
COFIPFKD_01942 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
COFIPFKD_01943 4.1e-67
COFIPFKD_01944 5.4e-203 xerS L Belongs to the 'phage' integrase family
COFIPFKD_01945 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COFIPFKD_01946 1.3e-273 pipD E Dipeptidase
COFIPFKD_01947 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
COFIPFKD_01948 3.3e-176 hrtB V ABC transporter permease
COFIPFKD_01949 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
COFIPFKD_01950 3.5e-111 G phosphoglycerate mutase
COFIPFKD_01951 4.1e-141 aroD S Alpha/beta hydrolase family
COFIPFKD_01952 2.2e-142 S Belongs to the UPF0246 family
COFIPFKD_01953 8.5e-133 cobB K SIR2 family
COFIPFKD_01954 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
COFIPFKD_01955 1.3e-124 terC P Integral membrane protein TerC family
COFIPFKD_01956 5.8e-64 yeaO S Protein of unknown function, DUF488
COFIPFKD_01957 8.9e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
COFIPFKD_01958 1.3e-290 glnP P ABC transporter permease
COFIPFKD_01959 3.4e-135 glnQ E ABC transporter, ATP-binding protein
COFIPFKD_01960 3.7e-66 K Helix-turn-helix domain, rpiR family
COFIPFKD_01961 7.1e-263 E ABC transporter, substratebinding protein
COFIPFKD_01962 9.1e-10 K peptidyl-tyrosine sulfation
COFIPFKD_01964 1.2e-128 S interspecies interaction between organisms
COFIPFKD_01965 2.7e-34
COFIPFKD_01968 4e-40 S CRISPR-associated protein (Cas_Csn2)
COFIPFKD_01969 1.1e-39 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COFIPFKD_01970 3e-130 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COFIPFKD_01971 3.7e-92 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
COFIPFKD_01972 1.8e-81 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
COFIPFKD_01973 4.6e-274 ycaM E amino acid
COFIPFKD_01974 3.1e-139 S Cysteine-rich secretory protein family
COFIPFKD_01975 4.2e-77 K MerR HTH family regulatory protein
COFIPFKD_01976 1.4e-262 lmrB EGP Major facilitator Superfamily
COFIPFKD_01977 3.1e-48 S Domain of unknown function (DUF4811)
COFIPFKD_01978 2.1e-114 3.6.1.27 I Acid phosphatase homologues
COFIPFKD_01979 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
COFIPFKD_01980 0.0 uvrA3 L excinuclease ABC, A subunit
COFIPFKD_01981 5.1e-113 L PFAM Integrase catalytic
COFIPFKD_01982 2e-57 clcA P chloride
COFIPFKD_01983 1e-107 L Transposase and inactivated derivatives, IS30 family
COFIPFKD_01984 1.5e-55 L Transposase and inactivated derivatives, IS30 family
COFIPFKD_01985 8.8e-41 clcA P chloride
COFIPFKD_01986 1.6e-60 clcA P chloride
COFIPFKD_01987 4.7e-26 K FCD
COFIPFKD_01988 8.7e-10 K FCD
COFIPFKD_01989 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COFIPFKD_01990 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COFIPFKD_01991 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
COFIPFKD_01992 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COFIPFKD_01993 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COFIPFKD_01994 5.1e-17
COFIPFKD_01995 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COFIPFKD_01996 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COFIPFKD_01997 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COFIPFKD_01998 9.4e-132 comFC S Competence protein
COFIPFKD_01999 4.7e-246 comFA L Helicase C-terminal domain protein
COFIPFKD_02000 5.1e-119 yvyE 3.4.13.9 S YigZ family
COFIPFKD_02001 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
COFIPFKD_02002 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
COFIPFKD_02003 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COFIPFKD_02004 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COFIPFKD_02005 5.2e-97 ymfM S Helix-turn-helix domain
COFIPFKD_02006 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
COFIPFKD_02007 1.9e-236 S Peptidase M16
COFIPFKD_02008 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
COFIPFKD_02009 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
COFIPFKD_02010 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
COFIPFKD_02011 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COFIPFKD_02012 2.6e-214 yubA S AI-2E family transporter
COFIPFKD_02013 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
COFIPFKD_02014 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
COFIPFKD_02015 4.2e-92 S SNARE associated Golgi protein
COFIPFKD_02016 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
COFIPFKD_02017 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COFIPFKD_02018 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COFIPFKD_02019 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
COFIPFKD_02020 6.8e-110 yjbK S CYTH
COFIPFKD_02021 4.6e-114 yjbH Q Thioredoxin
COFIPFKD_02022 4e-13 coiA 3.6.4.12 S Competence protein
COFIPFKD_02023 3.3e-132 coiA 3.6.4.12 S Competence protein
COFIPFKD_02024 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COFIPFKD_02025 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COFIPFKD_02026 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COFIPFKD_02027 8.5e-41 ptsH G phosphocarrier protein HPR
COFIPFKD_02028 5.3e-26
COFIPFKD_02029 2e-106 S domain protein
COFIPFKD_02030 2.5e-140 V ABC transporter
COFIPFKD_02031 5.9e-68 S Protein of unknown function (DUF3021)
COFIPFKD_02032 6e-86
COFIPFKD_02033 4.4e-172 S Domain of unknown function (DUF389)
COFIPFKD_02034 6.9e-100 V ATPases associated with a variety of cellular activities
COFIPFKD_02035 1.7e-139
COFIPFKD_02036 5.4e-113
COFIPFKD_02037 2.7e-83 S Protein of unknown function (DUF1211)
COFIPFKD_02038 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
COFIPFKD_02039 2.8e-119 3.6.1.55 F NUDIX domain
COFIPFKD_02040 1.5e-245 brnQ U Component of the transport system for branched-chain amino acids
COFIPFKD_02041 2.4e-73 S cog cog1373
COFIPFKD_02042 5.6e-179 S PFAM Archaeal ATPase
COFIPFKD_02043 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
COFIPFKD_02044 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
COFIPFKD_02045 9.2e-262 emrY EGP Major facilitator Superfamily
COFIPFKD_02046 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COFIPFKD_02047 1.1e-237 pyrP F Permease
COFIPFKD_02048 1.9e-22 K Putative DNA-binding domain
COFIPFKD_02049 8.4e-56 S Domain of unknown function (DUF4767)
COFIPFKD_02050 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COFIPFKD_02051 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
COFIPFKD_02052 3.2e-101 3.6.1.27 I Acid phosphatase homologues
COFIPFKD_02053 1.3e-51
COFIPFKD_02054 2.7e-57
COFIPFKD_02055 1.6e-11
COFIPFKD_02056 8.1e-126 S PAS domain
COFIPFKD_02057 4.8e-83 L PFAM transposase, IS4 family protein
COFIPFKD_02058 1.3e-161 L PFAM transposase, IS4 family protein
COFIPFKD_02059 3.3e-99 L PFAM transposase, IS4 family protein
COFIPFKD_02061 4e-36 S Cytochrome B5
COFIPFKD_02062 1.7e-167 arbZ I Phosphate acyltransferases
COFIPFKD_02063 8.7e-181 arbY M Glycosyl transferase family 8
COFIPFKD_02064 1.5e-143 arbY M Glycosyl transferase family 8
COFIPFKD_02065 2.1e-183 L DDE superfamily endonuclease
COFIPFKD_02066 8.8e-29
COFIPFKD_02069 4.9e-81 K Helix-turn-helix XRE-family like proteins

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)