ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMNKMKAA_00001 2.7e-17
HMNKMKAA_00004 1e-195 ampC V Beta-lactamase
HMNKMKAA_00005 7.6e-218 EGP Major facilitator Superfamily
HMNKMKAA_00006 4.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
HMNKMKAA_00007 8.5e-105 vanZ V VanZ like family
HMNKMKAA_00008 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMNKMKAA_00009 8.8e-265 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
HMNKMKAA_00010 7.5e-132 K Transcriptional regulatory protein, C terminal
HMNKMKAA_00011 7.7e-67 S SdpI/YhfL protein family
HMNKMKAA_00012 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMNKMKAA_00013 1.4e-172 patB 4.4.1.8 E Aminotransferase, class I
HMNKMKAA_00014 2.6e-39 patB 4.4.1.8 E Aminotransferase, class I
HMNKMKAA_00015 1.8e-79 M Protein of unknown function (DUF3737)
HMNKMKAA_00016 1.1e-13 M Protein of unknown function (DUF3737)
HMNKMKAA_00018 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMNKMKAA_00019 3.5e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
HMNKMKAA_00020 1.6e-21
HMNKMKAA_00021 3.8e-77 comGF U Putative Competence protein ComGF
HMNKMKAA_00022 2.3e-41
HMNKMKAA_00023 7.4e-71
HMNKMKAA_00024 3.1e-43 comGC U competence protein ComGC
HMNKMKAA_00025 1.3e-171 comGB NU type II secretion system
HMNKMKAA_00026 6.4e-179 comGA NU Type II IV secretion system protein
HMNKMKAA_00027 8.9e-133 yebC K Transcriptional regulatory protein
HMNKMKAA_00028 2e-94 S VanZ like family
HMNKMKAA_00029 3.2e-110 ylbE GM NAD(P)H-binding
HMNKMKAA_00030 9.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMNKMKAA_00032 7.4e-305 E Amino acid permease
HMNKMKAA_00033 1.4e-173 D Alpha beta
HMNKMKAA_00034 5.9e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMNKMKAA_00035 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMNKMKAA_00036 2.7e-141 licT K CAT RNA binding domain
HMNKMKAA_00037 1.2e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMNKMKAA_00038 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMNKMKAA_00039 2.5e-119
HMNKMKAA_00040 6e-76 K Penicillinase repressor
HMNKMKAA_00041 6.4e-148 S hydrolase
HMNKMKAA_00042 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMNKMKAA_00043 2e-172 ybbR S YbbR-like protein
HMNKMKAA_00044 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMNKMKAA_00045 1.2e-205 potD P ABC transporter
HMNKMKAA_00046 2.1e-127 potC P ABC transporter permease
HMNKMKAA_00047 5.4e-131 potB P ABC transporter permease
HMNKMKAA_00048 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMNKMKAA_00049 1.2e-163 murB 1.3.1.98 M Cell wall formation
HMNKMKAA_00050 3.1e-98 dnaQ 2.7.7.7 L DNA polymerase III
HMNKMKAA_00051 1.4e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HMNKMKAA_00052 8.2e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HMNKMKAA_00053 3.7e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMNKMKAA_00054 1.1e-153 ycsE S Sucrose-6F-phosphate phosphohydrolase
HMNKMKAA_00055 1.2e-94
HMNKMKAA_00056 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMNKMKAA_00057 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMNKMKAA_00058 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMNKMKAA_00059 3.3e-189 cggR K Putative sugar-binding domain
HMNKMKAA_00061 2.7e-140
HMNKMKAA_00062 3.3e-141
HMNKMKAA_00063 4.6e-274 ycaM E amino acid
HMNKMKAA_00064 2.1e-140 S Cysteine-rich secretory protein family
HMNKMKAA_00065 2.9e-32 S Protein of unknown function (DUF3021)
HMNKMKAA_00066 1.3e-44 K LytTr DNA-binding domain
HMNKMKAA_00067 6.2e-93 cylB V ABC-2 type transporter
HMNKMKAA_00068 4.7e-117 cylA V ABC transporter
HMNKMKAA_00069 3.2e-77 K MerR HTH family regulatory protein
HMNKMKAA_00070 2.4e-262 lmrB EGP Major facilitator Superfamily
HMNKMKAA_00071 1.6e-94 S Domain of unknown function (DUF4811)
HMNKMKAA_00072 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
HMNKMKAA_00073 4.2e-110 ybbL S ABC transporter, ATP-binding protein
HMNKMKAA_00074 0.0 S SH3-like domain
HMNKMKAA_00075 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMNKMKAA_00076 6.2e-171 whiA K May be required for sporulation
HMNKMKAA_00077 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMNKMKAA_00078 6.2e-165 rapZ S Displays ATPase and GTPase activities
HMNKMKAA_00079 9.1e-90 S Short repeat of unknown function (DUF308)
HMNKMKAA_00080 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMNKMKAA_00081 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMNKMKAA_00082 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMNKMKAA_00083 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMNKMKAA_00084 3.9e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMNKMKAA_00085 3.5e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMNKMKAA_00086 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMNKMKAA_00087 5.1e-17
HMNKMKAA_00088 5.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMNKMKAA_00089 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMNKMKAA_00090 4.2e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMNKMKAA_00091 3.1e-135 comFC S Competence protein
HMNKMKAA_00092 4e-245 comFA L Helicase C-terminal domain protein
HMNKMKAA_00093 6.6e-119 yvyE 3.4.13.9 S YigZ family
HMNKMKAA_00094 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
HMNKMKAA_00095 4.8e-219 rny S Endoribonuclease that initiates mRNA decay
HMNKMKAA_00096 1.2e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMNKMKAA_00097 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMNKMKAA_00098 2.2e-95 ymfM S Helix-turn-helix domain
HMNKMKAA_00099 1.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
HMNKMKAA_00100 3.9e-237 S Peptidase M16
HMNKMKAA_00101 5.9e-222 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HMNKMKAA_00102 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMNKMKAA_00103 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
HMNKMKAA_00104 4.6e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMNKMKAA_00105 2.6e-214 yubA S AI-2E family transporter
HMNKMKAA_00106 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HMNKMKAA_00107 1.4e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HMNKMKAA_00108 2.5e-92 S SNARE associated Golgi protein
HMNKMKAA_00109 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HMNKMKAA_00110 1.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMNKMKAA_00111 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMNKMKAA_00112 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
HMNKMKAA_00113 3.6e-111 yjbK S CYTH
HMNKMKAA_00114 1.2e-114 yjbH Q Thioredoxin
HMNKMKAA_00115 5.8e-160 coiA 3.6.4.12 S Competence protein
HMNKMKAA_00116 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMNKMKAA_00117 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMNKMKAA_00118 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMNKMKAA_00119 8.5e-41 ptsH G phosphocarrier protein HPR
HMNKMKAA_00120 5.3e-26
HMNKMKAA_00121 0.0 clpE O Belongs to the ClpA ClpB family
HMNKMKAA_00122 8.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
HMNKMKAA_00123 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMNKMKAA_00124 1.1e-140 hlyX S Transporter associated domain
HMNKMKAA_00125 1.6e-74
HMNKMKAA_00126 1.6e-85
HMNKMKAA_00127 1.9e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMNKMKAA_00128 4.6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMNKMKAA_00129 3.7e-176 D Alpha beta
HMNKMKAA_00130 9.4e-46
HMNKMKAA_00131 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMNKMKAA_00132 3.2e-74 nrdI F NrdI Flavodoxin like
HMNKMKAA_00133 1.1e-192 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMNKMKAA_00134 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMNKMKAA_00135 0.0 typA T GTP-binding protein TypA
HMNKMKAA_00136 5.4e-212 ftsW D Belongs to the SEDS family
HMNKMKAA_00137 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HMNKMKAA_00138 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HMNKMKAA_00139 1.3e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMNKMKAA_00140 1.3e-188 ylbL T Belongs to the peptidase S16 family
HMNKMKAA_00141 1.8e-79 comEA L Competence protein ComEA
HMNKMKAA_00142 0.0 comEC S Competence protein ComEC
HMNKMKAA_00143 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
HMNKMKAA_00144 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
HMNKMKAA_00145 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMNKMKAA_00146 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMNKMKAA_00147 8.3e-151
HMNKMKAA_00148 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMNKMKAA_00149 4e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMNKMKAA_00150 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMNKMKAA_00151 3.7e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
HMNKMKAA_00152 1.3e-22 yjeM E Amino Acid
HMNKMKAA_00153 1.3e-29 yjeM E Amino acid permease
HMNKMKAA_00154 2.3e-92 yjeM E Amino Acid
HMNKMKAA_00155 6.8e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMNKMKAA_00156 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMNKMKAA_00157 2.2e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMNKMKAA_00158 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMNKMKAA_00159 1.1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMNKMKAA_00160 7e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMNKMKAA_00161 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMNKMKAA_00162 3.8e-218 aspC 2.6.1.1 E Aminotransferase
HMNKMKAA_00163 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMNKMKAA_00164 1.5e-195 pbpX1 V Beta-lactamase
HMNKMKAA_00165 1.8e-298 I Protein of unknown function (DUF2974)
HMNKMKAA_00166 3.6e-39 C FMN_bind
HMNKMKAA_00167 1.9e-81
HMNKMKAA_00168 1.1e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HMNKMKAA_00169 9.3e-89 alkD L DNA alkylation repair enzyme
HMNKMKAA_00170 2.4e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMNKMKAA_00171 3.7e-128 K UTRA domain
HMNKMKAA_00172 1.6e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HMNKMKAA_00173 1.5e-59 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HMNKMKAA_00174 4.4e-86
HMNKMKAA_00175 2.5e-250 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMNKMKAA_00176 3.2e-71 S Domain of unknown function (DUF3284)
HMNKMKAA_00177 5.9e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMNKMKAA_00178 3.8e-120 gmuR K UTRA
HMNKMKAA_00179 3.7e-223 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMNKMKAA_00180 6.4e-273 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMNKMKAA_00181 4.2e-48 ypbG 2.7.1.2 GK ROK family
HMNKMKAA_00182 6.6e-79 ypbG 2.7.1.2 GK ROK family
HMNKMKAA_00183 1.2e-85 C nitroreductase
HMNKMKAA_00184 7e-89 S Domain of unknown function (DUF4767)
HMNKMKAA_00185 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMNKMKAA_00186 1.1e-147 yitS S Uncharacterised protein, DegV family COG1307
HMNKMKAA_00187 2.2e-102 3.6.1.27 I Acid phosphatase homologues
HMNKMKAA_00188 7.3e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMNKMKAA_00190 1.5e-178 MA20_14895 S Conserved hypothetical protein 698
HMNKMKAA_00191 1.2e-85 dps P Belongs to the Dps family
HMNKMKAA_00192 1.1e-14 K Acetyltransferase (GNAT) domain
HMNKMKAA_00193 1e-17 1.3.5.4 C FAD dependent oxidoreductase
HMNKMKAA_00194 1.3e-100 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMNKMKAA_00195 2.9e-70 S Putative adhesin
HMNKMKAA_00196 5.2e-75 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
HMNKMKAA_00197 3.9e-235 mepA V MATE efflux family protein
HMNKMKAA_00198 2e-106 S domain protein
HMNKMKAA_00199 1.1e-140 V ABC transporter
HMNKMKAA_00200 7e-69 S Protein of unknown function (DUF3021)
HMNKMKAA_00201 1.6e-73 K LytTr DNA-binding domain
HMNKMKAA_00202 2.8e-50 hxlR K HxlR-like helix-turn-helix
HMNKMKAA_00203 1.3e-72 L Transposase
HMNKMKAA_00204 4.4e-88 L Transposase
HMNKMKAA_00205 1.3e-162 S Domain of unknown function (DUF389)
HMNKMKAA_00206 3.8e-88
HMNKMKAA_00207 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMNKMKAA_00208 1.6e-168 dnaI L Primosomal protein DnaI
HMNKMKAA_00209 3.9e-251 dnaB L Replication initiation and membrane attachment
HMNKMKAA_00210 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMNKMKAA_00211 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMNKMKAA_00212 6.1e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMNKMKAA_00213 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMNKMKAA_00214 2.1e-136 qmcA O prohibitin homologues
HMNKMKAA_00215 1.3e-51 L RelB antitoxin
HMNKMKAA_00216 2.3e-192 S Bacteriocin helveticin-J
HMNKMKAA_00217 1.6e-46
HMNKMKAA_00218 1e-113 M Peptidase family M1 domain
HMNKMKAA_00219 6.1e-79 M Peptidase family M1 domain
HMNKMKAA_00220 1.1e-175 S SLAP domain
HMNKMKAA_00221 5.4e-237 mepA V MATE efflux family protein
HMNKMKAA_00222 3.8e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMNKMKAA_00223 1.8e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMNKMKAA_00224 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMNKMKAA_00225 5.8e-14 S Protein of unknown function (DUF805)
HMNKMKAA_00226 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMNKMKAA_00227 2.9e-221 ecsB U ABC transporter
HMNKMKAA_00228 2e-135 ecsA V ABC transporter, ATP-binding protein
HMNKMKAA_00229 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
HMNKMKAA_00230 3.9e-25
HMNKMKAA_00231 1.5e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMNKMKAA_00232 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HMNKMKAA_00233 1.1e-265
HMNKMKAA_00234 5.8e-188 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMNKMKAA_00235 0.0 L AAA domain
HMNKMKAA_00236 3.7e-232 yhaO L Ser Thr phosphatase family protein
HMNKMKAA_00237 1.6e-55 yheA S Belongs to the UPF0342 family
HMNKMKAA_00238 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMNKMKAA_00239 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMNKMKAA_00240 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HMNKMKAA_00241 8.8e-110 G Phosphoglycerate mutase family
HMNKMKAA_00242 1.6e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HMNKMKAA_00243 5.7e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HMNKMKAA_00244 1.1e-193 I transferase activity, transferring acyl groups other than amino-acyl groups
HMNKMKAA_00245 3.4e-176 S PFAM Archaeal ATPase
HMNKMKAA_00246 5.4e-42 S cog cog1373
HMNKMKAA_00247 1e-235 L transposase, IS605 OrfB family
HMNKMKAA_00248 2.4e-71 yniG EGP Major facilitator Superfamily
HMNKMKAA_00250 1.4e-94
HMNKMKAA_00252 6.3e-111
HMNKMKAA_00253 1.2e-143 K LytTr DNA-binding domain
HMNKMKAA_00254 1.1e-125 2.7.13.3 T GHKL domain
HMNKMKAA_00255 2.8e-221 patA 2.6.1.1 E Aminotransferase
HMNKMKAA_00256 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMNKMKAA_00257 6.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMNKMKAA_00258 4.6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMNKMKAA_00259 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMNKMKAA_00260 2.9e-60
HMNKMKAA_00261 6e-174 prmA J Ribosomal protein L11 methyltransferase
HMNKMKAA_00262 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMNKMKAA_00263 1.1e-248 yjjP S Putative threonine/serine exporter
HMNKMKAA_00264 1.3e-176 citR K Putative sugar-binding domain
HMNKMKAA_00265 3.4e-50
HMNKMKAA_00266 5.5e-09
HMNKMKAA_00267 2.9e-66 S Domain of unknown function DUF1828
HMNKMKAA_00268 7.4e-95 S UPF0397 protein
HMNKMKAA_00269 0.0 ykoD P ABC transporter, ATP-binding protein
HMNKMKAA_00270 3.6e-146 cbiQ P cobalt transport
HMNKMKAA_00271 1.8e-22
HMNKMKAA_00272 9.3e-72 yeaL S Protein of unknown function (DUF441)
HMNKMKAA_00273 1.4e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HMNKMKAA_00274 1.8e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HMNKMKAA_00275 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
HMNKMKAA_00276 2.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HMNKMKAA_00277 1.1e-152 ydjP I Alpha/beta hydrolase family
HMNKMKAA_00278 2.1e-274 P Sodium:sulfate symporter transmembrane region
HMNKMKAA_00279 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
HMNKMKAA_00280 2.1e-257 pepC 3.4.22.40 E Peptidase C1-like family
HMNKMKAA_00281 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMNKMKAA_00282 6.6e-262 frdC 1.3.5.4 C FAD binding domain
HMNKMKAA_00283 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMNKMKAA_00284 5.3e-74 metI P ABC transporter permease
HMNKMKAA_00285 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMNKMKAA_00286 2.9e-159 metQ2 P Belongs to the nlpA lipoprotein family
HMNKMKAA_00287 5.8e-177 F DNA/RNA non-specific endonuclease
HMNKMKAA_00288 0.0 aha1 P E1-E2 ATPase
HMNKMKAA_00289 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMNKMKAA_00290 1.5e-180 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMNKMKAA_00291 9.9e-250 yifK E Amino acid permease
HMNKMKAA_00292 5.9e-283 V ABC-type multidrug transport system, ATPase and permease components
HMNKMKAA_00293 1e-290 P ABC transporter
HMNKMKAA_00294 1.4e-37
HMNKMKAA_00296 5.8e-123 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HMNKMKAA_00297 6.5e-87 K GNAT family
HMNKMKAA_00298 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
HMNKMKAA_00299 1.7e-150 lmrB EGP Major facilitator Superfamily
HMNKMKAA_00300 4.3e-34 rmaI K Transcriptional regulator
HMNKMKAA_00302 1.5e-08 K Bacterial regulatory helix-turn-helix protein, lysR family
HMNKMKAA_00303 5.7e-08 S Protein of unknown function (DUF3021)
HMNKMKAA_00304 1e-84 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMNKMKAA_00305 0.0 L Plasmid pRiA4b ORF-3-like protein
HMNKMKAA_00306 1.2e-244 brnQ U Component of the transport system for branched-chain amino acids
HMNKMKAA_00307 2.8e-119 3.6.1.55 F NUDIX domain
HMNKMKAA_00308 5.2e-76 ltrA S Bacterial low temperature requirement A protein (LtrA)
HMNKMKAA_00309 6.8e-129 L Transposase
HMNKMKAA_00310 9.5e-69 L MobA/MobL family
HMNKMKAA_00311 3e-60 S Phage derived protein Gp49-like (DUF891)
HMNKMKAA_00312 1.3e-42 K Helix-turn-helix domain
HMNKMKAA_00313 1.4e-27 S Bacterial epsilon antitoxin
HMNKMKAA_00315 4.2e-274 V ABC transporter permease
HMNKMKAA_00316 2e-121 V ABC transporter, ATP-binding protein
HMNKMKAA_00317 1.1e-93 cmk 2.7.4.25, 5.3.1.12 F AAA domain
HMNKMKAA_00318 1.9e-39 S Pseudomonas avirulence D protein (AvrD)
HMNKMKAA_00319 7.5e-24 slyA K helix_turn_helix multiple antibiotic resistance protein
HMNKMKAA_00320 4.2e-101 tnpR L Resolvase, N terminal domain
HMNKMKAA_00321 1.8e-13 ytgB S Transglycosylase associated protein
HMNKMKAA_00322 4.3e-91 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HMNKMKAA_00323 3.8e-78 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMNKMKAA_00324 1.4e-78 marR K Transcriptional regulator
HMNKMKAA_00325 1.3e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMNKMKAA_00326 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMNKMKAA_00327 6.3e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HMNKMKAA_00328 1.9e-127 IQ reductase
HMNKMKAA_00329 1.9e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMNKMKAA_00330 1.1e-78 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMNKMKAA_00331 3.8e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HMNKMKAA_00332 2e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HMNKMKAA_00333 3.5e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMNKMKAA_00334 3.4e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HMNKMKAA_00335 1.9e-133 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HMNKMKAA_00336 7.2e-186 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMNKMKAA_00337 5.9e-89 bioY S BioY family
HMNKMKAA_00338 9.9e-29
HMNKMKAA_00339 3e-13 S Protein of unknown function (DUF1211)
HMNKMKAA_00340 1.1e-157 S Bacteriophage abortive infection AbiH
HMNKMKAA_00341 9.1e-179 fic S Fic/DOC family
HMNKMKAA_00342 4.1e-14 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMNKMKAA_00343 4.6e-29
HMNKMKAA_00344 9.6e-141 soj D AAA domain
HMNKMKAA_00345 7.4e-163 repA S Replication initiator protein A
HMNKMKAA_00346 5.1e-44 relB L Addiction module antitoxin, RelB DinJ family
HMNKMKAA_00347 1.2e-83
HMNKMKAA_00348 6.8e-41
HMNKMKAA_00349 2.7e-26
HMNKMKAA_00350 0.0 traA L MobA/MobL family
HMNKMKAA_00351 1.3e-12
HMNKMKAA_00352 1.7e-78
HMNKMKAA_00353 2.2e-49 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMNKMKAA_00354 1.7e-229 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HMNKMKAA_00355 5.2e-54 M Collagen binding domain
HMNKMKAA_00356 4.4e-227 M Collagen binding domain
HMNKMKAA_00357 6.9e-67 S Bacteriocin helveticin-J
HMNKMKAA_00358 5.3e-135 S SLAP domain
HMNKMKAA_00359 3.8e-303 S DNA primase
HMNKMKAA_00360 1.2e-42 K Helix-turn-helix XRE-family like proteins
HMNKMKAA_00361 1.4e-74
HMNKMKAA_00362 7.4e-157 L hmm pf00665
HMNKMKAA_00363 5.8e-100 L Helix-turn-helix domain
HMNKMKAA_00366 1.7e-246 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMNKMKAA_00367 5.6e-35 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMNKMKAA_00368 3.2e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
HMNKMKAA_00369 6.7e-202 pbpX1 V Beta-lactamase
HMNKMKAA_00370 1.7e-100 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HMNKMKAA_00371 7.5e-95 S ECF-type riboflavin transporter, S component
HMNKMKAA_00372 2e-230 S Putative peptidoglycan binding domain
HMNKMKAA_00373 3.1e-83 K Acetyltransferase (GNAT) domain
HMNKMKAA_00374 1.3e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMNKMKAA_00375 2.5e-191 yrvN L AAA C-terminal domain
HMNKMKAA_00376 1.1e-63 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMNKMKAA_00377 7.3e-283 treB G phosphotransferase system
HMNKMKAA_00378 8.9e-101 treR K UTRA
HMNKMKAA_00379 1.7e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HMNKMKAA_00380 1.3e-17
HMNKMKAA_00381 3.8e-240 G Bacterial extracellular solute-binding protein
HMNKMKAA_00382 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HMNKMKAA_00383 6.5e-237 XK27_01810 S Calcineurin-like phosphoesterase
HMNKMKAA_00386 5.8e-29 S CAAX amino terminal protease
HMNKMKAA_00387 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HMNKMKAA_00388 4.1e-210 hsdM 2.1.1.72 V type I restriction-modification system
HMNKMKAA_00389 1.9e-70 3.1.21.3 V Type I restriction modification DNA specificity domain
HMNKMKAA_00390 1.4e-151 L Belongs to the 'phage' integrase family
HMNKMKAA_00391 2.3e-74 3.1.21.3 V Type I restriction modification DNA specificity domain
HMNKMKAA_00392 1.1e-114 mrr L restriction endonuclease
HMNKMKAA_00393 3.5e-150 S Domain of unknown function (DUF3883)
HMNKMKAA_00394 1e-67 S Sel1-like repeats.
HMNKMKAA_00395 6.5e-78 S HIRAN
HMNKMKAA_00396 4.9e-31
HMNKMKAA_00397 2e-191
HMNKMKAA_00398 2.7e-100 3.1.4.37 S AAA domain
HMNKMKAA_00400 1.5e-303 oppA E ABC transporter substrate-binding protein
HMNKMKAA_00401 4.4e-284 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMNKMKAA_00402 2.8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMNKMKAA_00403 1.6e-168 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMNKMKAA_00404 1.8e-195 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMNKMKAA_00405 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HMNKMKAA_00406 0.0 FbpA K Fibronectin-binding protein
HMNKMKAA_00407 1.1e-66
HMNKMKAA_00408 1.9e-158 degV S EDD domain protein, DegV family
HMNKMKAA_00409 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMNKMKAA_00410 2.4e-203 xerS L Belongs to the 'phage' integrase family
HMNKMKAA_00411 4.1e-67
HMNKMKAA_00412 1.8e-110 XK27_00160 S Domain of unknown function (DUF5052)
HMNKMKAA_00413 1.5e-211 M Glycosyl hydrolases family 25
HMNKMKAA_00414 2e-39 S Transglycosylase associated protein
HMNKMKAA_00415 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
HMNKMKAA_00416 4.8e-134 G Bacterial extracellular solute-binding protein
HMNKMKAA_00417 1.1e-87 G Bacterial extracellular solute-binding protein
HMNKMKAA_00418 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
HMNKMKAA_00419 2e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMNKMKAA_00420 5.5e-124 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMNKMKAA_00421 0.0 kup P Transport of potassium into the cell
HMNKMKAA_00422 2.8e-176 rihB 3.2.2.1 F Nucleoside
HMNKMKAA_00423 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
HMNKMKAA_00424 4.7e-154 S hydrolase
HMNKMKAA_00425 1e-60 S Enterocin A Immunity
HMNKMKAA_00426 2.5e-138 glcR K DeoR C terminal sensor domain
HMNKMKAA_00427 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HMNKMKAA_00428 1.2e-152 rssA S Phospholipase, patatin family
HMNKMKAA_00429 7.5e-149 S hydrolase
HMNKMKAA_00430 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HMNKMKAA_00431 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
HMNKMKAA_00432 7e-81
HMNKMKAA_00433 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMNKMKAA_00434 2.1e-39
HMNKMKAA_00435 2.3e-119 C nitroreductase
HMNKMKAA_00436 2.2e-249 yhdP S Transporter associated domain
HMNKMKAA_00437 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMNKMKAA_00438 0.0 1.3.5.4 C FAD binding domain
HMNKMKAA_00439 2.3e-109 ydiN G Major Facilitator Superfamily
HMNKMKAA_00440 4.9e-104 K Transcriptional regulator, LysR family
HMNKMKAA_00441 4.1e-154 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMNKMKAA_00442 2e-190 ydiM G Major Facilitator Superfamily
HMNKMKAA_00443 1.9e-117 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMNKMKAA_00444 6.2e-107 K Bacterial regulatory helix-turn-helix protein, lysR family
HMNKMKAA_00445 2.8e-308 1.3.5.4 C FAD binding domain
HMNKMKAA_00446 9.3e-74 ydiN EGP Major Facilitator Superfamily
HMNKMKAA_00447 3.6e-121 aroD S Serine hydrolase (FSH1)
HMNKMKAA_00448 1.5e-71 aroD S Serine hydrolase (FSH1)
HMNKMKAA_00449 5.7e-97 ydiN EGP Major Facilitator Superfamily
HMNKMKAA_00450 4.9e-119 1.3.5.4 C FAD binding domain
HMNKMKAA_00451 1.6e-220 potE E amino acid
HMNKMKAA_00452 6.6e-117 M Glycosyl hydrolases family 25
HMNKMKAA_00453 2.3e-197 yfmL 3.6.4.13 L DEAD DEAH box helicase
HMNKMKAA_00454 7.8e-220 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMNKMKAA_00457 2.6e-161 V ABC transporter transmembrane region
HMNKMKAA_00458 7.7e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMNKMKAA_00459 1.1e-86 E Zn peptidase
HMNKMKAA_00460 8.6e-41 ps115 K Helix-turn-helix XRE-family like proteins
HMNKMKAA_00461 3.2e-42
HMNKMKAA_00462 1.9e-170 S Bacteriocin helveticin-J
HMNKMKAA_00463 1.8e-201 S SLAP domain
HMNKMKAA_00464 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMNKMKAA_00465 5.7e-69 rplI J Binds to the 23S rRNA
HMNKMKAA_00466 4.3e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMNKMKAA_00467 3.5e-166 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HMNKMKAA_00468 1.3e-165 degV S DegV family
HMNKMKAA_00469 1.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HMNKMKAA_00471 2.4e-16
HMNKMKAA_00472 8e-235 I Protein of unknown function (DUF2974)
HMNKMKAA_00473 9.8e-121 yhiD S MgtC family
HMNKMKAA_00475 2.1e-29
HMNKMKAA_00477 1.7e-145 S Putative ABC-transporter type IV
HMNKMKAA_00479 6.1e-76 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HMNKMKAA_00480 2.2e-228 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HMNKMKAA_00481 7.3e-26
HMNKMKAA_00482 1.2e-111 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HMNKMKAA_00483 7.9e-45 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMNKMKAA_00484 4.1e-37 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMNKMKAA_00485 0.0 oppA E ABC transporter substrate-binding protein
HMNKMKAA_00486 3.7e-177 K AI-2E family transporter
HMNKMKAA_00487 3.1e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HMNKMKAA_00488 4.1e-18
HMNKMKAA_00489 4e-195 G Major Facilitator
HMNKMKAA_00490 3.6e-35 G Major Facilitator
HMNKMKAA_00491 5.3e-136 XK27_08845 S ABC transporter, ATP-binding protein
HMNKMKAA_00492 7.4e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HMNKMKAA_00493 7.2e-178 ABC-SBP S ABC transporter
HMNKMKAA_00494 8.3e-136 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMNKMKAA_00495 5.5e-87
HMNKMKAA_00496 2.7e-74 M LysM domain
HMNKMKAA_00498 4.6e-83
HMNKMKAA_00499 2e-117 K Helix-turn-helix domain
HMNKMKAA_00500 0.0 tetP J elongation factor G
HMNKMKAA_00501 7.9e-146 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
HMNKMKAA_00502 2.7e-19
HMNKMKAA_00503 8.8e-10
HMNKMKAA_00505 8.4e-72 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HMNKMKAA_00506 1.9e-132 EGP Major facilitator Superfamily
HMNKMKAA_00509 1.9e-150 L Belongs to the 'phage' integrase family
HMNKMKAA_00510 5e-08 S Pfam:DUF955
HMNKMKAA_00511 1.1e-24 K Cro/C1-type HTH DNA-binding domain
HMNKMKAA_00512 9e-22 XK27_07105 K Helix-turn-helix XRE-family like proteins
HMNKMKAA_00513 2.3e-32 K Helix-turn-helix domain
HMNKMKAA_00514 3.2e-24 S Domain of unknown function (DUF771)
HMNKMKAA_00520 3.8e-10 ssb L Single-strand binding protein family
HMNKMKAA_00525 4.8e-25 S SLAP domain
HMNKMKAA_00526 9.2e-24 srtA 3.4.22.70 M sortase family
HMNKMKAA_00528 8.7e-41 M domain protein
HMNKMKAA_00529 2.1e-36 M domain protein
HMNKMKAA_00533 1.4e-141 U TraM recognition site of TraD and TraG
HMNKMKAA_00534 1.9e-31 I mechanosensitive ion channel activity
HMNKMKAA_00536 3.2e-14
HMNKMKAA_00537 4.4e-158 trsE S COG0433 Predicted ATPase
HMNKMKAA_00538 1.6e-32 3.5.1.28 NU amidase activity
HMNKMKAA_00541 2.9e-16 CO COG0526, thiol-disulfide isomerase and thioredoxins
HMNKMKAA_00548 1.4e-50 S COG0790 FOG TPR repeat, SEL1 subfamily
HMNKMKAA_00549 1.8e-36 L Protein of unknown function (DUF3991)
HMNKMKAA_00550 1.6e-19 EL Toprim-like
HMNKMKAA_00551 2.3e-42 S PFAM Uncharacterised protein family UPF0150
HMNKMKAA_00552 1.7e-51 E Pfam:DUF955
HMNKMKAA_00553 1.2e-109 glf 5.4.99.9 M UDP-galactopyranose mutase
HMNKMKAA_00554 7.5e-94 M Glycosyl transferases group 1
HMNKMKAA_00557 5e-69
HMNKMKAA_00558 1.4e-80 M Glycosyl transferase family 2
HMNKMKAA_00559 6.4e-56 GT2,GT4 M Glycosyltransferase GT-D fold
HMNKMKAA_00560 4.1e-126 waaB GT4 M Glycosyl transferases group 1
HMNKMKAA_00561 2.7e-119 cps1D M Domain of unknown function (DUF4422)
HMNKMKAA_00562 3.7e-122 rfbP M Bacterial sugar transferase
HMNKMKAA_00563 3.1e-144 ywqE 3.1.3.48 GM PHP domain protein
HMNKMKAA_00564 4.7e-119 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HMNKMKAA_00565 1.4e-148 epsB M biosynthesis protein
HMNKMKAA_00566 7.7e-178 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMNKMKAA_00567 1.3e-47 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
HMNKMKAA_00568 1.3e-41 relB L RelB antitoxin
HMNKMKAA_00570 2.7e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMNKMKAA_00571 3.5e-175 S Cysteine-rich secretory protein family
HMNKMKAA_00572 4.6e-41
HMNKMKAA_00573 4.9e-117 M NlpC/P60 family
HMNKMKAA_00574 1.4e-136 M NlpC P60 family protein
HMNKMKAA_00575 9.5e-87 M NlpC/P60 family
HMNKMKAA_00576 2.7e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
HMNKMKAA_00577 2.3e-42
HMNKMKAA_00578 8.5e-279 S O-antigen ligase like membrane protein
HMNKMKAA_00579 7.4e-112
HMNKMKAA_00580 1.9e-77 nrdI F NrdI Flavodoxin like
HMNKMKAA_00581 2.6e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMNKMKAA_00582 9.5e-68
HMNKMKAA_00583 3.5e-111 yvpB S Peptidase_C39 like family
HMNKMKAA_00584 8.7e-84 S Threonine/Serine exporter, ThrE
HMNKMKAA_00585 4.8e-137 thrE S Putative threonine/serine exporter
HMNKMKAA_00586 3.4e-291 S ABC transporter
HMNKMKAA_00587 2.5e-62
HMNKMKAA_00588 3.7e-91 rimL J Acetyltransferase (GNAT) domain
HMNKMKAA_00589 7.4e-95
HMNKMKAA_00590 6.5e-125 S Protein of unknown function (DUF554)
HMNKMKAA_00591 4e-210 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMNKMKAA_00592 0.0 pepF E oligoendopeptidase F
HMNKMKAA_00594 2.7e-213 2.1.1.14 E methionine synthase, vitamin-B12 independent
HMNKMKAA_00595 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMNKMKAA_00596 1.1e-08 S CAAX amino terminal protease
HMNKMKAA_00597 8.5e-129 S CAAX amino terminal protease
HMNKMKAA_00598 2.7e-18 M Lysin motif
HMNKMKAA_00599 8.5e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMNKMKAA_00600 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
HMNKMKAA_00601 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMNKMKAA_00602 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMNKMKAA_00603 8.7e-229 S Tetratricopeptide repeat protein
HMNKMKAA_00604 3.3e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMNKMKAA_00605 1.3e-282 V ABC transporter transmembrane region
HMNKMKAA_00606 2.2e-49
HMNKMKAA_00607 4.4e-90 speG J Acetyltransferase (GNAT) domain
HMNKMKAA_00608 1e-57 K Acetyltransferase (GNAT) domain
HMNKMKAA_00609 1.3e-64 S Protein of unknown function (DUF2785)
HMNKMKAA_00610 4.8e-48 S MazG-like family
HMNKMKAA_00611 1.1e-65
HMNKMKAA_00612 7.5e-119 glsA 3.5.1.2 E Belongs to the glutaminase family
HMNKMKAA_00613 1.7e-262
HMNKMKAA_00614 1.3e-93 rimL J Acetyltransferase (GNAT) domain
HMNKMKAA_00615 1.1e-139 S Alpha/beta hydrolase family
HMNKMKAA_00616 4.9e-52 yxaM EGP Major facilitator Superfamily
HMNKMKAA_00617 1.1e-112 yxaM EGP Major facilitator Superfamily
HMNKMKAA_00618 1.9e-60 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
HMNKMKAA_00619 3.8e-120 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
HMNKMKAA_00620 3.5e-80 S AAA domain
HMNKMKAA_00621 7.8e-66 3.6.1.55 F NUDIX domain
HMNKMKAA_00622 3.7e-145 2.4.2.3 F Phosphorylase superfamily
HMNKMKAA_00623 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HMNKMKAA_00624 1.9e-98 yagE E Amino acid permease
HMNKMKAA_00625 7.4e-74 yagE E Amino acid permease
HMNKMKAA_00626 1.9e-86 3.4.21.96 S SLAP domain
HMNKMKAA_00627 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMNKMKAA_00628 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMNKMKAA_00629 1.2e-107 hlyIII S protein, hemolysin III
HMNKMKAA_00630 2e-144 DegV S Uncharacterised protein, DegV family COG1307
HMNKMKAA_00631 7.1e-36 yozE S Belongs to the UPF0346 family
HMNKMKAA_00632 6.5e-67 yjcE P NhaP-type Na H and K H
HMNKMKAA_00633 4.2e-175 yjcE P Sodium proton antiporter
HMNKMKAA_00634 7.3e-155 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMNKMKAA_00635 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMNKMKAA_00636 2.2e-151 dprA LU DNA protecting protein DprA
HMNKMKAA_00637 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMNKMKAA_00638 2.3e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMNKMKAA_00639 2.2e-141 xerC D Phage integrase, N-terminal SAM-like domain
HMNKMKAA_00640 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMNKMKAA_00641 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMNKMKAA_00643 8.7e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HMNKMKAA_00644 1.1e-128 manY G PTS system
HMNKMKAA_00645 1e-173 manN G system, mannose fructose sorbose family IID component
HMNKMKAA_00646 9.9e-64 manO S Domain of unknown function (DUF956)
HMNKMKAA_00647 5.1e-159 K Transcriptional regulator
HMNKMKAA_00648 1.4e-90 maa S transferase hexapeptide repeat
HMNKMKAA_00649 4.3e-245 cycA E Amino acid permease
HMNKMKAA_00650 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMNKMKAA_00651 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMNKMKAA_00652 0.0 mtlR K Mga helix-turn-helix domain
HMNKMKAA_00653 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HMNKMKAA_00654 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMNKMKAA_00655 2e-219 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HMNKMKAA_00656 1.8e-133 4.1.1.44 S Carboxymuconolactone decarboxylase family
HMNKMKAA_00657 1.6e-32
HMNKMKAA_00658 6.7e-69 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HMNKMKAA_00659 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HMNKMKAA_00660 0.0 S TerB-C domain
HMNKMKAA_00661 1.7e-251 P P-loop Domain of unknown function (DUF2791)
HMNKMKAA_00662 0.0 lhr L DEAD DEAH box helicase
HMNKMKAA_00663 1.9e-59
HMNKMKAA_00664 1.1e-141 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMNKMKAA_00666 9.1e-202 amtB P ammonium transporter
HMNKMKAA_00668 1e-61 psiE S Phosphate-starvation-inducible E
HMNKMKAA_00669 3.8e-113 yncA 2.3.1.79 S Maltose acetyltransferase
HMNKMKAA_00670 1.7e-69 S Iron-sulphur cluster biosynthesis
HMNKMKAA_00672 4.6e-31
HMNKMKAA_00673 3.6e-173 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HMNKMKAA_00674 6.2e-12
HMNKMKAA_00675 1.1e-115 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMNKMKAA_00676 1.1e-28 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMNKMKAA_00677 3.4e-78 M LysM domain protein
HMNKMKAA_00678 1.2e-165 D nuclear chromosome segregation
HMNKMKAA_00679 1.2e-105 G Phosphoglycerate mutase family
HMNKMKAA_00680 2.2e-88 G Histidine phosphatase superfamily (branch 1)
HMNKMKAA_00681 1.5e-118 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HMNKMKAA_00682 3e-114 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMNKMKAA_00684 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMNKMKAA_00685 3.1e-212 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HMNKMKAA_00686 6.1e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HMNKMKAA_00687 2.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HMNKMKAA_00688 4.4e-144 K SIS domain
HMNKMKAA_00689 2.5e-227 slpX S SLAP domain
HMNKMKAA_00690 3.3e-232 npr 1.11.1.1 C NADH oxidase
HMNKMKAA_00693 3.5e-299 oppA2 E ABC transporter, substratebinding protein
HMNKMKAA_00694 2.5e-179
HMNKMKAA_00695 1.3e-125 gntR1 K UTRA
HMNKMKAA_00696 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HMNKMKAA_00697 1.4e-133 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMNKMKAA_00698 9e-206 csaB M Glycosyl transferases group 1
HMNKMKAA_00699 9.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMNKMKAA_00700 4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMNKMKAA_00701 0.0 pacL 3.6.3.8 P P-type ATPase
HMNKMKAA_00702 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMNKMKAA_00703 6.4e-260 epsU S Polysaccharide biosynthesis protein
HMNKMKAA_00704 9.1e-135 M Glycosyltransferase sugar-binding region containing DXD motif
HMNKMKAA_00705 1.8e-83 ydcK S Belongs to the SprT family
HMNKMKAA_00707 2.5e-86 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HMNKMKAA_00708 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMNKMKAA_00709 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMNKMKAA_00710 2.9e-202 camS S sex pheromone
HMNKMKAA_00711 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMNKMKAA_00712 7.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMNKMKAA_00713 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMNKMKAA_00714 7.2e-172 yegS 2.7.1.107 G Lipid kinase
HMNKMKAA_00715 4.3e-108 ybhL S Belongs to the BI1 family
HMNKMKAA_00716 2.6e-57
HMNKMKAA_00717 2.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
HMNKMKAA_00718 3.1e-243 nhaC C Na H antiporter NhaC
HMNKMKAA_00719 5.4e-200 pbpX V Beta-lactamase
HMNKMKAA_00720 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMNKMKAA_00721 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
HMNKMKAA_00726 3.3e-259 emrY EGP Major facilitator Superfamily
HMNKMKAA_00727 2e-91 yxdD K Bacterial regulatory proteins, tetR family
HMNKMKAA_00728 0.0 4.2.1.53 S Myosin-crossreactive antigen
HMNKMKAA_00729 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
HMNKMKAA_00730 4.1e-158 S reductase
HMNKMKAA_00731 3.5e-34
HMNKMKAA_00732 7.5e-291 K Putative DNA-binding domain
HMNKMKAA_00733 3.4e-239 pyrP F Permease
HMNKMKAA_00734 4.7e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMNKMKAA_00735 2.7e-261 emrY EGP Major facilitator Superfamily
HMNKMKAA_00736 1.1e-217 mdtG EGP Major facilitator Superfamily
HMNKMKAA_00737 2.4e-136
HMNKMKAA_00738 1.8e-99
HMNKMKAA_00739 5.9e-185 pepA E M42 glutamyl aminopeptidase
HMNKMKAA_00740 9e-311 ybiT S ABC transporter, ATP-binding protein
HMNKMKAA_00741 5.9e-174 S Aldo keto reductase
HMNKMKAA_00742 6.1e-151
HMNKMKAA_00743 1.8e-240 steT E amino acid
HMNKMKAA_00744 7.8e-94 steT E amino acid
HMNKMKAA_00745 9.6e-124 steT E amino acid
HMNKMKAA_00746 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HMNKMKAA_00747 3.8e-148 glnH ET ABC transporter
HMNKMKAA_00748 1.4e-80 K Transcriptional regulator, MarR family
HMNKMKAA_00749 8.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
HMNKMKAA_00750 0.0 V ABC transporter transmembrane region
HMNKMKAA_00751 3.8e-102 S ABC-type cobalt transport system, permease component
HMNKMKAA_00752 5.2e-254 G MFS/sugar transport protein
HMNKMKAA_00753 6.8e-113 udk 2.7.1.48 F Zeta toxin
HMNKMKAA_00754 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMNKMKAA_00755 3.4e-149 glnH ET ABC transporter substrate-binding protein
HMNKMKAA_00756 9.7e-91 gluC P ABC transporter permease
HMNKMKAA_00757 4.7e-109 glnP P ABC transporter permease
HMNKMKAA_00758 8.5e-165 S Protein of unknown function (DUF2974)
HMNKMKAA_00759 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMNKMKAA_00760 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMNKMKAA_00761 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMNKMKAA_00762 6.7e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMNKMKAA_00763 1.4e-39 yajC U Preprotein translocase
HMNKMKAA_00764 5.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMNKMKAA_00765 5.9e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMNKMKAA_00766 4.7e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HMNKMKAA_00767 1.4e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMNKMKAA_00768 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMNKMKAA_00769 2e-42 yrzL S Belongs to the UPF0297 family
HMNKMKAA_00770 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMNKMKAA_00771 1.1e-50 yrzB S Belongs to the UPF0473 family
HMNKMKAA_00772 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMNKMKAA_00773 3.5e-54 trxA O Belongs to the thioredoxin family
HMNKMKAA_00774 6.3e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMNKMKAA_00775 1.1e-71 yslB S Protein of unknown function (DUF2507)
HMNKMKAA_00776 1.3e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMNKMKAA_00777 1.6e-111 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMNKMKAA_00778 8.1e-146 ykuT M mechanosensitive ion channel
HMNKMKAA_00779 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMNKMKAA_00780 1.3e-36
HMNKMKAA_00781 1.7e-212 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMNKMKAA_00782 4.9e-182 ccpA K catabolite control protein A
HMNKMKAA_00783 6.8e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMNKMKAA_00784 4.3e-55
HMNKMKAA_00785 8.9e-275 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMNKMKAA_00786 1.7e-105 yutD S Protein of unknown function (DUF1027)
HMNKMKAA_00787 6.9e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMNKMKAA_00788 3.7e-100 S Protein of unknown function (DUF1461)
HMNKMKAA_00789 1.5e-115 dedA S SNARE-like domain protein
HMNKMKAA_00790 2.3e-184 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HMNKMKAA_00793 8.1e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMNKMKAA_00794 5.1e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMNKMKAA_00796 8.2e-48 pspC KT PspC domain
HMNKMKAA_00797 3.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
HMNKMKAA_00798 3.3e-272 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMNKMKAA_00799 9.1e-106 pncA Q Isochorismatase family
HMNKMKAA_00800 9.3e-124 L Bifunctional protein
HMNKMKAA_00801 1.8e-45 L Psort location Cytoplasmic, score
HMNKMKAA_00802 1.2e-78 yphH S Cupin domain
HMNKMKAA_00804 1.3e-75 S PAS domain
HMNKMKAA_00805 2.6e-289 ytgP S Polysaccharide biosynthesis protein
HMNKMKAA_00806 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMNKMKAA_00807 6.4e-122 3.6.1.27 I Acid phosphatase homologues
HMNKMKAA_00808 1.8e-170 K LysR substrate binding domain
HMNKMKAA_00809 4.7e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMNKMKAA_00810 1.1e-231 ndh 1.6.99.3 C NADH dehydrogenase
HMNKMKAA_00811 3e-162 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HMNKMKAA_00812 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMNKMKAA_00813 1.3e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HMNKMKAA_00814 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HMNKMKAA_00815 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HMNKMKAA_00816 3e-179 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HMNKMKAA_00817 2.3e-273 cydA 1.10.3.14 C ubiquinol oxidase
HMNKMKAA_00818 1.7e-143 ybbH_2 K rpiR family
HMNKMKAA_00819 8.1e-196 S Bacterial protein of unknown function (DUF871)
HMNKMKAA_00820 3.4e-182 yfeW 3.4.16.4 V Beta-lactamase
HMNKMKAA_00821 3.8e-141 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMNKMKAA_00822 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMNKMKAA_00823 5.9e-261 qacA EGP Major facilitator Superfamily
HMNKMKAA_00824 4.1e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMNKMKAA_00827 1.4e-107 psaA P Belongs to the bacterial solute-binding protein 9 family
HMNKMKAA_00828 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMNKMKAA_00829 1.2e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMNKMKAA_00830 1.3e-38 S RelB antitoxin
HMNKMKAA_00831 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HMNKMKAA_00832 0.0 S membrane
HMNKMKAA_00833 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HMNKMKAA_00834 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMNKMKAA_00835 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMNKMKAA_00836 6.9e-119 gluP 3.4.21.105 S Rhomboid family
HMNKMKAA_00837 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HMNKMKAA_00838 1e-61 yqhL P Rhodanese-like protein
HMNKMKAA_00839 9.2e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMNKMKAA_00840 3.4e-225 ynbB 4.4.1.1 P aluminum resistance
HMNKMKAA_00841 2e-263 glnA 6.3.1.2 E glutamine synthetase
HMNKMKAA_00842 5.1e-170
HMNKMKAA_00843 7.8e-148
HMNKMKAA_00844 1.2e-31 S protein encoded in hypervariable junctions of pilus gene clusters
HMNKMKAA_00846 6.4e-161 L PFAM transposase, IS4 family protein
HMNKMKAA_00847 7.2e-113 yeaN P Transporter, major facilitator family protein
HMNKMKAA_00848 2.1e-178 glf 5.4.99.9 M UDP-galactopyranose mutase
HMNKMKAA_00849 4.2e-269 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HMNKMKAA_00850 8.3e-157 K LysR substrate binding domain
HMNKMKAA_00851 5.6e-204 EK Aminotransferase, class I
HMNKMKAA_00852 6.5e-90 alkD L DNA alkylation repair enzyme
HMNKMKAA_00853 7e-74 L Resolvase, N terminal domain
HMNKMKAA_00854 1.5e-210 L TIGRFAM transposase, IS605 OrfB family
HMNKMKAA_00855 2.2e-44 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HMNKMKAA_00856 1.9e-26
HMNKMKAA_00857 1.2e-159 L PFAM transposase, IS4 family protein
HMNKMKAA_00858 3.1e-33
HMNKMKAA_00859 2.4e-147 S Sucrose-6F-phosphate phosphohydrolase
HMNKMKAA_00860 0.0 mco Q Multicopper oxidase
HMNKMKAA_00861 5.7e-25
HMNKMKAA_00862 1.9e-158 metQ1 P Belongs to the nlpA lipoprotein family
HMNKMKAA_00863 1.6e-168 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HMNKMKAA_00864 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMNKMKAA_00865 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMNKMKAA_00866 2.7e-199 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMNKMKAA_00867 2.9e-162 cjaA ET ABC transporter substrate-binding protein
HMNKMKAA_00868 9.7e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMNKMKAA_00869 2.8e-117 P ABC transporter permease
HMNKMKAA_00870 5.1e-111 papP P ABC transporter, permease protein
HMNKMKAA_00872 3.6e-63 yodB K Transcriptional regulator, HxlR family
HMNKMKAA_00873 2.3e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMNKMKAA_00874 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMNKMKAA_00875 2.9e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMNKMKAA_00876 2.5e-86 S Aminoacyl-tRNA editing domain
HMNKMKAA_00877 7.2e-225 S SLAP domain
HMNKMKAA_00878 1.3e-37 S CAAX protease self-immunity
HMNKMKAA_00879 9.8e-34 S CAAX protease self-immunity
HMNKMKAA_00880 8.5e-17
HMNKMKAA_00881 1.3e-277 arlS 2.7.13.3 T Histidine kinase
HMNKMKAA_00882 1.2e-126 K response regulator
HMNKMKAA_00883 9.4e-98 yceD S Uncharacterized ACR, COG1399
HMNKMKAA_00884 2e-216 ylbM S Belongs to the UPF0348 family
HMNKMKAA_00885 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMNKMKAA_00886 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HMNKMKAA_00887 1.2e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMNKMKAA_00888 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
HMNKMKAA_00889 4.2e-84 yqeG S HAD phosphatase, family IIIA
HMNKMKAA_00890 9.2e-201 tnpB L Putative transposase DNA-binding domain
HMNKMKAA_00891 5.6e-154 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HMNKMKAA_00892 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMNKMKAA_00893 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMNKMKAA_00894 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMNKMKAA_00895 1.7e-35 yyaR K Acetyltransferase (GNAT) domain
HMNKMKAA_00896 5.1e-49
HMNKMKAA_00897 2.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMNKMKAA_00898 1.7e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMNKMKAA_00899 6.3e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
HMNKMKAA_00900 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
HMNKMKAA_00901 8.5e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMNKMKAA_00902 5.9e-76 S PAS domain
HMNKMKAA_00903 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HMNKMKAA_00904 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HMNKMKAA_00905 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HMNKMKAA_00906 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HMNKMKAA_00907 4.7e-210 msmX P Belongs to the ABC transporter superfamily
HMNKMKAA_00908 1.7e-213 malE G Bacterial extracellular solute-binding protein
HMNKMKAA_00909 3.3e-250 malF P Binding-protein-dependent transport system inner membrane component
HMNKMKAA_00910 3.3e-147 malG P ABC transporter permease
HMNKMKAA_00912 4.9e-90 ymdB S Macro domain protein
HMNKMKAA_00913 3e-213 mdtG EGP Major facilitator Superfamily
HMNKMKAA_00914 5.1e-176
HMNKMKAA_00915 2.8e-47 lysM M LysM domain
HMNKMKAA_00916 0.0 pepN 3.4.11.2 E aminopeptidase
HMNKMKAA_00917 5.7e-251 dtpT U amino acid peptide transporter
HMNKMKAA_00918 7.3e-19 S Sugar efflux transporter for intercellular exchange
HMNKMKAA_00919 3e-78 XK27_02470 K LytTr DNA-binding domain
HMNKMKAA_00920 5.4e-128 liaI S membrane
HMNKMKAA_00922 8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMNKMKAA_00923 1.1e-155 S reductase
HMNKMKAA_00924 2e-149 yxeH S hydrolase
HMNKMKAA_00925 1.5e-55 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMNKMKAA_00926 1.1e-110 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMNKMKAA_00927 5.9e-237 yfnA E Amino Acid
HMNKMKAA_00928 1.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
HMNKMKAA_00929 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMNKMKAA_00930 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMNKMKAA_00931 1.4e-294 I Acyltransferase
HMNKMKAA_00932 5.8e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMNKMKAA_00933 1.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMNKMKAA_00934 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
HMNKMKAA_00935 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMNKMKAA_00936 5.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMNKMKAA_00937 2.3e-23 S Protein of unknown function (DUF2929)
HMNKMKAA_00938 0.0 dnaE 2.7.7.7 L DNA polymerase
HMNKMKAA_00939 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMNKMKAA_00940 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMNKMKAA_00941 3.6e-168 cvfB S S1 domain
HMNKMKAA_00942 2.2e-165 xerD D recombinase XerD
HMNKMKAA_00943 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMNKMKAA_00944 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMNKMKAA_00945 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMNKMKAA_00946 1.5e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMNKMKAA_00947 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMNKMKAA_00948 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMNKMKAA_00949 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMNKMKAA_00950 1.7e-29 secG U Preprotein translocase
HMNKMKAA_00951 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMNKMKAA_00952 1.5e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMNKMKAA_00953 2.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
HMNKMKAA_00954 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HMNKMKAA_00966 3.3e-95
HMNKMKAA_00967 2.3e-234 V ABC transporter transmembrane region
HMNKMKAA_00968 7e-246 KLT serine threonine protein kinase
HMNKMKAA_00971 5.8e-96
HMNKMKAA_00973 3.2e-83 D VirC1 protein
HMNKMKAA_00974 6.2e-15 L Belongs to the 'phage' integrase family
HMNKMKAA_00975 1.5e-109 L Belongs to the 'phage' integrase family
HMNKMKAA_00976 4.7e-128 sip L Belongs to the 'phage' integrase family
HMNKMKAA_00977 9e-12 xre K sequence-specific DNA binding
HMNKMKAA_00978 1.4e-10 S Helix-turn-helix domain
HMNKMKAA_00979 9.3e-20
HMNKMKAA_00982 2.6e-20
HMNKMKAA_00983 2.9e-46 L Replication initiation factor
HMNKMKAA_00984 2.2e-19
HMNKMKAA_01001 7.1e-263 E ABC transporter, substratebinding protein
HMNKMKAA_01003 2.4e-36 L An automated process has identified a potential problem with this gene model
HMNKMKAA_01004 2.5e-50 L An automated process has identified a potential problem with this gene model
HMNKMKAA_01005 1.3e-252 E Amino acid permease
HMNKMKAA_01006 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HMNKMKAA_01007 7.8e-61
HMNKMKAA_01008 3.5e-260 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HMNKMKAA_01009 0.0 O Belongs to the peptidase S8 family
HMNKMKAA_01010 1.3e-174 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HMNKMKAA_01011 1.9e-93 dhaL 2.7.1.121 S Dak2
HMNKMKAA_01012 3.8e-55 dhaM 2.7.1.121 S PTS system fructose IIA component
HMNKMKAA_01013 2e-121 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HMNKMKAA_01014 3.1e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMNKMKAA_01015 3.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HMNKMKAA_01016 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HMNKMKAA_01017 2.5e-186 lacR K Transcriptional regulator
HMNKMKAA_01018 0.0 lacS G Transporter
HMNKMKAA_01019 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HMNKMKAA_01020 5.6e-103 tag 3.2.2.20 L Methyladenine glycosylase
HMNKMKAA_01021 1e-235 stp_1 EGP Major facilitator Superfamily
HMNKMKAA_01022 6.8e-60 MA20_41110 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMNKMKAA_01023 4.7e-123 H ThiF family
HMNKMKAA_01024 6.3e-207 arsR K DNA-binding transcription factor activity
HMNKMKAA_01025 6.2e-97 K Transcriptional regulator
HMNKMKAA_01027 1.2e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HMNKMKAA_01028 1.6e-57 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMNKMKAA_01029 1.4e-39 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMNKMKAA_01030 3.6e-29 relB L RelB antitoxin
HMNKMKAA_01031 4.3e-133 D CobQ CobB MinD ParA nucleotide binding domain protein
HMNKMKAA_01033 5e-167 repA S Replication initiator protein A
HMNKMKAA_01034 1.1e-26
HMNKMKAA_01035 4e-119 S protein conserved in bacteria
HMNKMKAA_01036 6.8e-41
HMNKMKAA_01037 1.6e-26
HMNKMKAA_01038 0.0 L MobA MobL family protein
HMNKMKAA_01039 6.9e-242 L Transposase DDE domain
HMNKMKAA_01040 2.2e-75 L Integrase core domain
HMNKMKAA_01041 5.1e-85 lsgC M Glycosyl transferases group 1
HMNKMKAA_01042 7.3e-107
HMNKMKAA_01043 1.4e-175 L Transposase and inactivated derivatives, IS30 family
HMNKMKAA_01046 3.8e-16
HMNKMKAA_01047 1.3e-11 S Transglycosylase associated protein
HMNKMKAA_01048 1.2e-81 S Asp23 family, cell envelope-related function
HMNKMKAA_01049 2.3e-88
HMNKMKAA_01050 1.2e-100 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HMNKMKAA_01051 3e-78
HMNKMKAA_01052 6.1e-24 S RelB antitoxin
HMNKMKAA_01053 5.2e-279 L Transposase
HMNKMKAA_01054 2.2e-215 ywhK S Membrane
HMNKMKAA_01055 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
HMNKMKAA_01056 5.1e-292 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMNKMKAA_01057 4.6e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
HMNKMKAA_01058 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMNKMKAA_01059 1.2e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMNKMKAA_01060 1.7e-176 pbpX2 V Beta-lactamase
HMNKMKAA_01061 1.1e-132 S Protein of unknown function (DUF975)
HMNKMKAA_01062 2.7e-137 lysA2 M Glycosyl hydrolases family 25
HMNKMKAA_01063 3.5e-291 ytgP S Polysaccharide biosynthesis protein
HMNKMKAA_01064 1.9e-36
HMNKMKAA_01065 0.0 XK27_06780 V ABC transporter permease
HMNKMKAA_01066 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
HMNKMKAA_01067 1.7e-235 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMNKMKAA_01068 2.6e-166 S Alpha/beta hydrolase of unknown function (DUF915)
HMNKMKAA_01069 0.0 clpE O AAA domain (Cdc48 subfamily)
HMNKMKAA_01070 1.1e-62 K Helix-turn-helix XRE-family like proteins
HMNKMKAA_01072 1.4e-90 KLT Protein kinase domain
HMNKMKAA_01073 1.4e-113 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
HMNKMKAA_01074 1.9e-65 L An automated process has identified a potential problem with this gene model
HMNKMKAA_01075 8.4e-135 S SLAP domain
HMNKMKAA_01076 0.0 oppA E ABC transporter substrate-binding protein
HMNKMKAA_01077 6.4e-84 dps P Belongs to the Dps family
HMNKMKAA_01078 3.1e-22 npr 1.11.1.1 C NADH oxidase
HMNKMKAA_01079 0.0 pepO 3.4.24.71 O Peptidase family M13
HMNKMKAA_01080 0.0 mdlB V ABC transporter
HMNKMKAA_01081 0.0 mdlA V ABC transporter
HMNKMKAA_01082 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
HMNKMKAA_01083 3e-38 ynzC S UPF0291 protein
HMNKMKAA_01084 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMNKMKAA_01085 3.7e-145 E GDSL-like Lipase/Acylhydrolase family
HMNKMKAA_01086 3.2e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMNKMKAA_01087 9.3e-214 S SLAP domain
HMNKMKAA_01088 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMNKMKAA_01089 5e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMNKMKAA_01090 2.2e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMNKMKAA_01091 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMNKMKAA_01092 5.8e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMNKMKAA_01093 4.6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMNKMKAA_01094 2.2e-260 yfnA E amino acid
HMNKMKAA_01095 0.0 V FtsX-like permease family
HMNKMKAA_01096 2.4e-133 cysA V ABC transporter, ATP-binding protein
HMNKMKAA_01098 1.2e-287 pipD E Dipeptidase
HMNKMKAA_01099 1.7e-163 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMNKMKAA_01100 0.0 smc D Required for chromosome condensation and partitioning
HMNKMKAA_01101 5.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMNKMKAA_01102 6e-308 oppA E ABC transporter substrate-binding protein
HMNKMKAA_01103 3.3e-290 oppA E ABC transporter substrate-binding protein
HMNKMKAA_01104 2.5e-132 oppC P Binding-protein-dependent transport system inner membrane component
HMNKMKAA_01105 4.4e-172 oppB P ABC transporter permease
HMNKMKAA_01106 1.5e-170 oppF P Belongs to the ABC transporter superfamily
HMNKMKAA_01107 1.5e-191 oppD P Belongs to the ABC transporter superfamily
HMNKMKAA_01108 4.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMNKMKAA_01109 2.7e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMNKMKAA_01110 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMNKMKAA_01111 6.4e-304 yloV S DAK2 domain fusion protein YloV
HMNKMKAA_01112 4e-57 asp S Asp23 family, cell envelope-related function
HMNKMKAA_01113 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMNKMKAA_01114 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMNKMKAA_01115 1.7e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMNKMKAA_01116 3.3e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMNKMKAA_01117 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HMNKMKAA_01118 1.3e-139 stp 3.1.3.16 T phosphatase
HMNKMKAA_01119 5.2e-243 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMNKMKAA_01120 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMNKMKAA_01121 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMNKMKAA_01122 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMNKMKAA_01123 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HMNKMKAA_01124 4.2e-77 6.3.3.2 S ASCH
HMNKMKAA_01125 7.4e-308 recN L May be involved in recombinational repair of damaged DNA
HMNKMKAA_01126 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HMNKMKAA_01127 2.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMNKMKAA_01128 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMNKMKAA_01129 2.4e-192 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMNKMKAA_01130 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMNKMKAA_01131 2.1e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMNKMKAA_01132 3.4e-71 yqhY S Asp23 family, cell envelope-related function
HMNKMKAA_01133 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMNKMKAA_01134 1.5e-195 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMNKMKAA_01135 3.9e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMNKMKAA_01136 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMNKMKAA_01137 1.4e-150 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMNKMKAA_01138 1.4e-256 S Uncharacterized protein conserved in bacteria (DUF2325)
HMNKMKAA_01140 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMNKMKAA_01141 6.5e-302 S Predicted membrane protein (DUF2207)
HMNKMKAA_01142 1.6e-160 cinI S Serine hydrolase (FSH1)
HMNKMKAA_01143 1.7e-208 M Glycosyl hydrolases family 25
HMNKMKAA_01145 2.9e-178 I Carboxylesterase family
HMNKMKAA_01146 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HMNKMKAA_01147 1.1e-276 V ABC-type multidrug transport system, ATPase and permease components
HMNKMKAA_01148 8.3e-293 V ABC-type multidrug transport system, ATPase and permease components
HMNKMKAA_01149 1.7e-148 S haloacid dehalogenase-like hydrolase
HMNKMKAA_01150 2.6e-52
HMNKMKAA_01151 1.9e-37
HMNKMKAA_01152 5.9e-42 S Alpha beta hydrolase
HMNKMKAA_01153 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMNKMKAA_01154 1.2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HMNKMKAA_01155 7.1e-46
HMNKMKAA_01156 1e-148 glcU U sugar transport
HMNKMKAA_01157 9.9e-251 lctP C L-lactate permease
HMNKMKAA_01158 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMNKMKAA_01159 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMNKMKAA_01160 4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMNKMKAA_01161 5.5e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMNKMKAA_01162 2.5e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMNKMKAA_01163 2.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMNKMKAA_01164 2.7e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMNKMKAA_01165 1.1e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMNKMKAA_01166 1.8e-75 clcA P chloride
HMNKMKAA_01167 7.9e-285 lsa S ABC transporter
HMNKMKAA_01168 1.4e-44
HMNKMKAA_01169 2.6e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HMNKMKAA_01170 1e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMNKMKAA_01171 2.2e-51 S Iron-sulfur cluster assembly protein
HMNKMKAA_01172 3.7e-135 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMNKMKAA_01173 2.2e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HMNKMKAA_01174 4.4e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMNKMKAA_01175 4.7e-227 L COG3547 Transposase and inactivated derivatives
HMNKMKAA_01176 2.1e-277 yjeM E Amino Acid
HMNKMKAA_01177 1.5e-303 S SLAP domain
HMNKMKAA_01178 1.2e-137 S Fic/DOC family
HMNKMKAA_01179 3.7e-287
HMNKMKAA_01180 3.3e-38 ropB K Transcriptional regulator
HMNKMKAA_01181 1.1e-121 S CAAX protease self-immunity
HMNKMKAA_01182 9.5e-195 S DUF218 domain
HMNKMKAA_01183 0.0 macB_3 V ABC transporter, ATP-binding protein
HMNKMKAA_01184 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HMNKMKAA_01185 2.8e-100 S ECF transporter, substrate-specific component
HMNKMKAA_01186 1.8e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
HMNKMKAA_01187 4.3e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
HMNKMKAA_01188 1.2e-283 xylG 3.6.3.17 S ABC transporter
HMNKMKAA_01189 4.3e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
HMNKMKAA_01190 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
HMNKMKAA_01191 4.3e-160 yeaE S Aldo/keto reductase family
HMNKMKAA_01192 1.3e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMNKMKAA_01193 6.3e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HMNKMKAA_01194 3.1e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HMNKMKAA_01195 2e-66
HMNKMKAA_01196 6.1e-135 cof S haloacid dehalogenase-like hydrolase
HMNKMKAA_01197 2.2e-230 pbuG S permease
HMNKMKAA_01198 4.6e-93 K Helix-turn-helix XRE-family like proteins
HMNKMKAA_01199 7.7e-10 V ATPases associated with a variety of cellular activities
HMNKMKAA_01200 6.2e-277 V ABC-type multidrug transport system, ATPase and permease components
HMNKMKAA_01201 5.4e-284 V ABC-type multidrug transport system, ATPase and permease components
HMNKMKAA_01202 1.2e-73
HMNKMKAA_01203 2.3e-21 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HMNKMKAA_01204 3.2e-69 hipB K sequence-specific DNA binding
HMNKMKAA_01205 1.4e-41 S SnoaL-like domain
HMNKMKAA_01206 0.0 L PLD-like domain
HMNKMKAA_01207 4e-101 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
HMNKMKAA_01208 5.2e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMNKMKAA_01209 5.2e-281 thrC 4.2.3.1 E Threonine synthase
HMNKMKAA_01210 5e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HMNKMKAA_01211 9.5e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMNKMKAA_01212 2.6e-115
HMNKMKAA_01213 3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMNKMKAA_01214 2.7e-76
HMNKMKAA_01215 3.8e-107 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMNKMKAA_01216 2e-117 S Peptidase family M23
HMNKMKAA_01217 2.2e-226 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HMNKMKAA_01218 1.9e-112 plsC 2.3.1.51 I Acyltransferase
HMNKMKAA_01219 1.6e-191 yabB 2.1.1.223 L Methyltransferase small domain
HMNKMKAA_01220 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HMNKMKAA_01221 5.9e-183 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMNKMKAA_01222 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMNKMKAA_01223 2e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMNKMKAA_01224 1.9e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMNKMKAA_01225 9.6e-136 cdsA 2.7.7.41 I Belongs to the CDS family
HMNKMKAA_01226 7.5e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMNKMKAA_01227 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMNKMKAA_01228 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMNKMKAA_01229 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HMNKMKAA_01230 3.2e-196 nusA K Participates in both transcription termination and antitermination
HMNKMKAA_01231 8.8e-47 ylxR K Protein of unknown function (DUF448)
HMNKMKAA_01232 3.2e-47 rplGA J ribosomal protein
HMNKMKAA_01233 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMNKMKAA_01234 3e-60 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMNKMKAA_01237 2.8e-149 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMNKMKAA_01238 2.1e-61 L An automated process has identified a potential problem with this gene model
HMNKMKAA_01239 1.6e-180 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMNKMKAA_01240 4.8e-53 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HMNKMKAA_01241 6.1e-48 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HMNKMKAA_01242 2e-158 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMNKMKAA_01243 1.1e-191 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMNKMKAA_01244 1.5e-211 KQ helix_turn_helix, mercury resistance
HMNKMKAA_01245 0.0 O Subtilase family
HMNKMKAA_01246 6e-191 O Holliday junction DNA helicase ruvB N-terminus
HMNKMKAA_01247 9.8e-225
HMNKMKAA_01248 1.2e-157 L COG2826 Transposase and inactivated derivatives, IS30 family
HMNKMKAA_01249 4.5e-221 I transferase activity, transferring acyl groups other than amino-acyl groups
HMNKMKAA_01250 1.2e-94 3.6.1.55 L NUDIX domain
HMNKMKAA_01251 2.3e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HMNKMKAA_01252 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HMNKMKAA_01253 3.6e-99 M ErfK YbiS YcfS YnhG
HMNKMKAA_01254 1.6e-32 S Toxin ToxN, type III toxin-antitoxin system
HMNKMKAA_01256 1.7e-28
HMNKMKAA_01257 2.3e-143 repA S Replication initiator protein A
HMNKMKAA_01259 1.4e-125 D Sporulation initiation inhibitor
HMNKMKAA_01260 1.9e-79 L COG1961 Site-specific recombinases, DNA invertase Pin homologs
HMNKMKAA_01261 4.6e-12 K Bacterial regulatory proteins, tetR family
HMNKMKAA_01262 1.4e-76 S Protein of unknown function with HXXEE motif
HMNKMKAA_01263 3.7e-157 3.3.1.1 H adenosylhomocysteinase activity
HMNKMKAA_01264 1.9e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMNKMKAA_01265 2.1e-167 EGP Major facilitator Superfamily
HMNKMKAA_01266 5.6e-195 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMNKMKAA_01267 1.3e-72 pncA Q Isochorismatase family
HMNKMKAA_01268 3.8e-86 3.6.1.13, 3.6.1.55 F NUDIX domain
HMNKMKAA_01269 3.9e-41 tag 3.2.2.20 L Methyladenine glycosylase
HMNKMKAA_01270 6.2e-76 K Transcriptional regulator
HMNKMKAA_01271 4.5e-176 K helix_turn_helix, Arsenical Resistance Operon Repressor
HMNKMKAA_01272 2.3e-21 H ThiF family
HMNKMKAA_01273 2.6e-234 stp_1 EGP Major Facilitator Superfamily
HMNKMKAA_01274 4.5e-38 Q Methyltransferase domain
HMNKMKAA_01275 1.2e-76
HMNKMKAA_01276 2.6e-94 S Protein of unknown function (DUF805)
HMNKMKAA_01277 1.9e-68 O OsmC-like protein
HMNKMKAA_01278 1.2e-208 EGP Major facilitator Superfamily
HMNKMKAA_01279 9.5e-223 sptS 2.7.13.3 T Histidine kinase
HMNKMKAA_01280 8.5e-106 K response regulator
HMNKMKAA_01281 1.3e-113 2.7.6.5 T Region found in RelA / SpoT proteins
HMNKMKAA_01282 1e-281 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HMNKMKAA_01283 0.0 rafA 3.2.1.22 G alpha-galactosidase
HMNKMKAA_01284 2.8e-210 msmX P Belongs to the ABC transporter superfamily
HMNKMKAA_01285 5.2e-153 msmG P Binding-protein-dependent transport system inner membrane component
HMNKMKAA_01286 1.4e-156 msmF P Binding-protein-dependent transport system inner membrane component
HMNKMKAA_01287 1.4e-239 msmE G Bacterial extracellular solute-binding protein
HMNKMKAA_01288 1.9e-159 scrR K Periplasmic binding protein domain
HMNKMKAA_01289 6.1e-35
HMNKMKAA_01290 5.4e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMNKMKAA_01291 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HMNKMKAA_01292 2.1e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMNKMKAA_01293 7.2e-36 lacZ 3.2.1.23 G -beta-galactosidase
HMNKMKAA_01295 2.1e-131 cobQ S glutamine amidotransferase
HMNKMKAA_01296 2.1e-82 M NlpC/P60 family
HMNKMKAA_01298 6e-160
HMNKMKAA_01301 2.3e-36
HMNKMKAA_01302 8.6e-165 EG EamA-like transporter family
HMNKMKAA_01303 7e-167 EG EamA-like transporter family
HMNKMKAA_01304 9.4e-140 yicL EG EamA-like transporter family
HMNKMKAA_01305 2.5e-107
HMNKMKAA_01306 1.6e-109
HMNKMKAA_01307 1.2e-186 XK27_05540 S DUF218 domain
HMNKMKAA_01308 4.1e-71 yheS_2 S ATPases associated with a variety of cellular activities
HMNKMKAA_01309 2.1e-67 yheS_2 S ATPases associated with a variety of cellular activities
HMNKMKAA_01310 1.6e-88
HMNKMKAA_01311 3.9e-57
HMNKMKAA_01312 2.4e-29 S Protein conserved in bacteria
HMNKMKAA_01313 3.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMNKMKAA_01314 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMNKMKAA_01315 7e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMNKMKAA_01318 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HMNKMKAA_01319 1.9e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
HMNKMKAA_01320 8e-95
HMNKMKAA_01321 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HMNKMKAA_01322 9e-98
HMNKMKAA_01323 4.4e-109 K LysR substrate binding domain
HMNKMKAA_01324 1e-20
HMNKMKAA_01325 5.1e-223 S Sterol carrier protein domain
HMNKMKAA_01326 7.6e-97 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HMNKMKAA_01327 8.8e-110 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
HMNKMKAA_01328 5.3e-37 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMNKMKAA_01329 3.6e-38 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMNKMKAA_01330 7.2e-236 arcA 3.5.3.6 E Arginine
HMNKMKAA_01331 5.9e-136 lysR5 K LysR substrate binding domain
HMNKMKAA_01332 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HMNKMKAA_01333 1.3e-24 S Metal binding domain of Ada
HMNKMKAA_01334 5.6e-40 ybhL S Belongs to the BI1 family
HMNKMKAA_01336 1.1e-211 S Bacterial protein of unknown function (DUF871)
HMNKMKAA_01337 2.4e-200 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HMNKMKAA_01338 9.7e-97 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMNKMKAA_01339 1.4e-113 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMNKMKAA_01340 9e-38
HMNKMKAA_01342 1.3e-15 S Domain of Unknown Function with PDB structure (DUF3850)
HMNKMKAA_01343 3.6e-95 D VirC1 protein
HMNKMKAA_01345 7e-37 S RelB antitoxin
HMNKMKAA_01346 2.4e-38 C coenzyme F420-1:gamma-L-glutamate ligase activity
HMNKMKAA_01348 1e-33 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
HMNKMKAA_01349 4.9e-17 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
HMNKMKAA_01351 1.5e-33
HMNKMKAA_01352 7.5e-209 V ABC transporter transmembrane region
HMNKMKAA_01354 2.1e-100 L An automated process has identified a potential problem with this gene model
HMNKMKAA_01355 4.1e-23 S CAAX protease self-immunity
HMNKMKAA_01356 2.5e-129 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMNKMKAA_01357 6.8e-51 S SLAP domain
HMNKMKAA_01358 1.9e-289 clcA P chloride
HMNKMKAA_01359 2.1e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMNKMKAA_01360 3.7e-112
HMNKMKAA_01361 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HMNKMKAA_01362 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMNKMKAA_01363 4.7e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMNKMKAA_01364 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMNKMKAA_01365 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMNKMKAA_01366 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HMNKMKAA_01367 5.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMNKMKAA_01368 1.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMNKMKAA_01369 1.3e-122 L An automated process has identified a potential problem with this gene model
HMNKMKAA_01370 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HMNKMKAA_01371 2.5e-39 rpmE2 J Ribosomal protein L31
HMNKMKAA_01372 2.9e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMNKMKAA_01373 4.8e-250 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMNKMKAA_01374 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMNKMKAA_01375 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMNKMKAA_01376 2.2e-128 S (CBS) domain
HMNKMKAA_01377 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMNKMKAA_01378 1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMNKMKAA_01379 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMNKMKAA_01380 1.6e-33 yabO J S4 domain protein
HMNKMKAA_01381 6.8e-60 divIC D Septum formation initiator
HMNKMKAA_01382 6.3e-63 yabR J S1 RNA binding domain
HMNKMKAA_01383 1.5e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMNKMKAA_01384 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMNKMKAA_01385 1.1e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMNKMKAA_01386 2.3e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMNKMKAA_01387 4.9e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMNKMKAA_01389 1.6e-08
HMNKMKAA_01390 1.6e-08
HMNKMKAA_01392 3.2e-80 yebR 1.8.4.14 T GAF domain-containing protein
HMNKMKAA_01393 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMNKMKAA_01394 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMNKMKAA_01395 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMNKMKAA_01396 8.1e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HMNKMKAA_01397 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMNKMKAA_01398 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMNKMKAA_01399 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMNKMKAA_01400 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HMNKMKAA_01401 2e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMNKMKAA_01402 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
HMNKMKAA_01403 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMNKMKAA_01404 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMNKMKAA_01405 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMNKMKAA_01406 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMNKMKAA_01407 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMNKMKAA_01408 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMNKMKAA_01409 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HMNKMKAA_01410 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMNKMKAA_01411 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMNKMKAA_01412 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMNKMKAA_01413 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMNKMKAA_01414 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMNKMKAA_01415 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMNKMKAA_01416 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMNKMKAA_01417 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMNKMKAA_01418 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMNKMKAA_01419 2.3e-24 rpmD J Ribosomal protein L30
HMNKMKAA_01420 2.6e-71 rplO J Binds to the 23S rRNA
HMNKMKAA_01421 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMNKMKAA_01422 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMNKMKAA_01423 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMNKMKAA_01424 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMNKMKAA_01425 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMNKMKAA_01426 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMNKMKAA_01427 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMNKMKAA_01428 1.4e-60 rplQ J Ribosomal protein L17
HMNKMKAA_01429 3.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMNKMKAA_01430 7.8e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMNKMKAA_01431 2.6e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMNKMKAA_01432 6.6e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMNKMKAA_01433 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMNKMKAA_01434 1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HMNKMKAA_01435 4.8e-180 L Phage integrase family
HMNKMKAA_01436 2.5e-23
HMNKMKAA_01437 1.9e-160 repB EP Plasmid replication protein
HMNKMKAA_01438 3.1e-34
HMNKMKAA_01439 6.2e-183 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HMNKMKAA_01440 9e-42
HMNKMKAA_01441 1.1e-130
HMNKMKAA_01442 2.2e-68 S Metallo-beta-lactamase superfamily
HMNKMKAA_01443 2e-57
HMNKMKAA_01444 3.2e-145 M Belongs to the glycosyl hydrolase 28 family
HMNKMKAA_01445 1.3e-78 K Acetyltransferase (GNAT) domain
HMNKMKAA_01446 6.7e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HMNKMKAA_01447 5.1e-119 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMNKMKAA_01448 6.4e-134 S membrane transporter protein
HMNKMKAA_01449 2.6e-126 gpmB G Belongs to the phosphoglycerate mutase family
HMNKMKAA_01450 5.1e-162 czcD P cation diffusion facilitator family transporter
HMNKMKAA_01451 1.4e-23
HMNKMKAA_01452 1.2e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMNKMKAA_01453 1.1e-183 S AAA domain
HMNKMKAA_01454 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMNKMKAA_01455 8.7e-38
HMNKMKAA_01456 3.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
HMNKMKAA_01457 1.9e-52
HMNKMKAA_01458 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HMNKMKAA_01459 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMNKMKAA_01460 1.3e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMNKMKAA_01461 5.2e-278 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMNKMKAA_01462 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMNKMKAA_01463 5e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMNKMKAA_01464 5.5e-95 sigH K Belongs to the sigma-70 factor family
HMNKMKAA_01465 1.7e-34
HMNKMKAA_01466 1.5e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HMNKMKAA_01467 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMNKMKAA_01468 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMNKMKAA_01469 3.1e-101 nusG K Participates in transcription elongation, termination and antitermination
HMNKMKAA_01470 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMNKMKAA_01471 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMNKMKAA_01472 7.3e-158 pstS P Phosphate
HMNKMKAA_01473 3.9e-163 pstC P probably responsible for the translocation of the substrate across the membrane
HMNKMKAA_01474 1.2e-155 pstA P Phosphate transport system permease protein PstA
HMNKMKAA_01475 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMNKMKAA_01476 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMNKMKAA_01477 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
HMNKMKAA_01478 4.6e-61 L An automated process has identified a potential problem with this gene model
HMNKMKAA_01479 1.3e-12 GT2,GT4 M family 8
HMNKMKAA_01480 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMNKMKAA_01481 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMNKMKAA_01482 5.1e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HMNKMKAA_01483 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
HMNKMKAA_01484 9e-26
HMNKMKAA_01485 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMNKMKAA_01486 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMNKMKAA_01487 2.4e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HMNKMKAA_01488 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMNKMKAA_01489 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMNKMKAA_01490 1.1e-34 S Protein of unknown function (DUF2508)
HMNKMKAA_01491 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMNKMKAA_01492 8.9e-53 yaaQ S Cyclic-di-AMP receptor
HMNKMKAA_01493 3e-156 holB 2.7.7.7 L DNA polymerase III
HMNKMKAA_01494 1.8e-59 yabA L Involved in initiation control of chromosome replication
HMNKMKAA_01495 3e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMNKMKAA_01496 3.4e-140 fat 3.1.2.21 I Acyl-ACP thioesterase
HMNKMKAA_01497 2.4e-87 S ECF transporter, substrate-specific component
HMNKMKAA_01498 3.1e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HMNKMKAA_01499 4.8e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HMNKMKAA_01500 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMNKMKAA_01501 6.6e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMNKMKAA_01502 3e-150 3.1.3.48 T Tyrosine phosphatase family
HMNKMKAA_01503 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
HMNKMKAA_01504 7.1e-95 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HMNKMKAA_01505 2.4e-110 K WHG domain
HMNKMKAA_01506 8e-38
HMNKMKAA_01507 2.8e-276 pipD E Dipeptidase
HMNKMKAA_01508 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HMNKMKAA_01509 4.7e-175 hrtB V ABC transporter permease
HMNKMKAA_01510 3.1e-95 ygfC K Bacterial regulatory proteins, tetR family
HMNKMKAA_01511 5.5e-112 G phosphoglycerate mutase
HMNKMKAA_01512 1.9e-141 aroD S Alpha/beta hydrolase family
HMNKMKAA_01513 3.4e-143 S Belongs to the UPF0246 family
HMNKMKAA_01514 9e-121
HMNKMKAA_01515 4.3e-157 2.7.7.12 C Domain of unknown function (DUF4931)
HMNKMKAA_01516 5.1e-194 S Putative peptidoglycan binding domain
HMNKMKAA_01517 4e-16
HMNKMKAA_01518 1.2e-227 L COG3547 Transposase and inactivated derivatives
HMNKMKAA_01519 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
HMNKMKAA_01520 4.2e-74 C Aldo keto reductase
HMNKMKAA_01521 3.1e-09 S aldo-keto reductase (NADP) activity
HMNKMKAA_01522 7.5e-24 S aldo-keto reductase (NADP) activity
HMNKMKAA_01523 1.2e-65 M LysM domain protein
HMNKMKAA_01524 1.1e-152 xerD L Phage integrase, N-terminal SAM-like domain
HMNKMKAA_01525 7.9e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMNKMKAA_01526 9.2e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMNKMKAA_01527 1.1e-12 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HMNKMKAA_01528 2.1e-116 mmuP E amino acid
HMNKMKAA_01529 4.5e-274 pepV 3.5.1.18 E dipeptidase PepV
HMNKMKAA_01530 2.4e-92 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HMNKMKAA_01531 1.7e-284 E Amino acid permease
HMNKMKAA_01532 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HMNKMKAA_01533 1.6e-246 ynbB 4.4.1.1 P aluminum resistance
HMNKMKAA_01535 1.8e-31
HMNKMKAA_01536 4.1e-139
HMNKMKAA_01537 1.2e-215 V ABC transporter transmembrane region
HMNKMKAA_01538 3.9e-35 V ABC transporter transmembrane region
HMNKMKAA_01539 1e-22 S Putative adhesin
HMNKMKAA_01540 1.1e-226 pbuG S permease
HMNKMKAA_01541 3.9e-147 S haloacid dehalogenase-like hydrolase
HMNKMKAA_01542 5.3e-226 S cog cog1373
HMNKMKAA_01543 3.1e-60 K Transcriptional regulator
HMNKMKAA_01544 3.5e-66 K Transcriptional regulator
HMNKMKAA_01545 1.3e-35 ymfI 1.1.1.100, 1.3.1.28 S oxidoreductase activity
HMNKMKAA_01546 1e-46 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HMNKMKAA_01547 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMNKMKAA_01548 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
HMNKMKAA_01549 3e-232 pbuG S permease
HMNKMKAA_01550 8.6e-128 K helix_turn_helix, mercury resistance
HMNKMKAA_01551 6.1e-26 S CAAX protease self-immunity
HMNKMKAA_01552 2.6e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMNKMKAA_01553 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMNKMKAA_01554 2.5e-73
HMNKMKAA_01555 9.5e-71 M CHAP domain
HMNKMKAA_01556 1.9e-101 M CHAP domain
HMNKMKAA_01557 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HMNKMKAA_01558 8.1e-295 scrB 3.2.1.26 GH32 G invertase
HMNKMKAA_01559 1e-184 scrR K helix_turn _helix lactose operon repressor
HMNKMKAA_01560 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMNKMKAA_01561 0.0 uup S ABC transporter, ATP-binding protein
HMNKMKAA_01562 2.8e-157 L COG2963 Transposase and inactivated derivatives
HMNKMKAA_01563 1.7e-42
HMNKMKAA_01564 2.3e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
HMNKMKAA_01565 5.1e-149 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMNKMKAA_01566 2.8e-157 isdE P Periplasmic binding protein
HMNKMKAA_01567 8.2e-123 M Iron Transport-associated domain
HMNKMKAA_01568 3e-09 isdH M Iron Transport-associated domain
HMNKMKAA_01569 4.9e-89
HMNKMKAA_01570 2.2e-113 S SLAP domain
HMNKMKAA_01571 2.9e-47 S Uncharacterized protein conserved in bacteria (DUF2263)
HMNKMKAA_01572 4.4e-83 S An automated process has identified a potential problem with this gene model
HMNKMKAA_01573 1.6e-138 S Protein of unknown function (DUF3100)
HMNKMKAA_01574 2.9e-224 3.5.1.47 S Peptidase dimerisation domain
HMNKMKAA_01575 1.5e-208 Q Imidazolonepropionase and related amidohydrolases
HMNKMKAA_01576 7.7e-310 oppA E ABC transporter
HMNKMKAA_01577 2.4e-43 L transposase activity
HMNKMKAA_01578 5.2e-97 cadD P Cadmium resistance transporter
HMNKMKAA_01580 1.1e-105 S SLAP domain
HMNKMKAA_01581 1.7e-52 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMNKMKAA_01582 3.9e-26
HMNKMKAA_01583 2.5e-86 K DNA-templated transcription, initiation
HMNKMKAA_01585 7.8e-73
HMNKMKAA_01586 1.1e-190 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HMNKMKAA_01587 2.1e-95 S SLAP domain
HMNKMKAA_01588 1.1e-40 S Protein of unknown function (DUF2922)
HMNKMKAA_01589 5.5e-30
HMNKMKAA_01590 1.2e-70 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMNKMKAA_01591 4.6e-227 N Uncharacterized conserved protein (DUF2075)
HMNKMKAA_01592 6.2e-205 pbpX1 V Beta-lactamase
HMNKMKAA_01593 0.0 L Helicase C-terminal domain protein
HMNKMKAA_01594 9.6e-272 E amino acid
HMNKMKAA_01595 2.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HMNKMKAA_01598 6.2e-193 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMNKMKAA_01600 1.6e-39
HMNKMKAA_01601 2.4e-63
HMNKMKAA_01602 1.9e-30
HMNKMKAA_01603 5.6e-144 K LytTr DNA-binding domain
HMNKMKAA_01604 4.9e-238 2.7.13.3 T GHKL domain
HMNKMKAA_01606 2.3e-210 S CAAX protease self-immunity
HMNKMKAA_01608 9.2e-220 S CAAX protease self-immunity
HMNKMKAA_01610 1.9e-68
HMNKMKAA_01611 6.4e-11
HMNKMKAA_01612 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HMNKMKAA_01613 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMNKMKAA_01614 2.2e-165 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
HMNKMKAA_01615 3e-173 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMNKMKAA_01616 1.1e-121 casE S CRISPR_assoc
HMNKMKAA_01617 6.8e-133 casD S CRISPR-associated protein (Cas_Cas5)
HMNKMKAA_01618 2.4e-198 casC L CT1975-like protein
HMNKMKAA_01619 1.5e-109 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
HMNKMKAA_01620 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
HMNKMKAA_01621 0.0 cas3 L CRISPR-associated helicase cas3
HMNKMKAA_01622 5.1e-81 ykuL S (CBS) domain
HMNKMKAA_01623 0.0 cadA P P-type ATPase
HMNKMKAA_01624 1.3e-61
HMNKMKAA_01625 5.7e-206 napA P Sodium/hydrogen exchanger family
HMNKMKAA_01626 2.5e-281 V ABC transporter transmembrane region
HMNKMKAA_01627 7.2e-158 mutR K Helix-turn-helix XRE-family like proteins
HMNKMKAA_01628 3.8e-52
HMNKMKAA_01629 7.6e-156 EGP Major facilitator Superfamily
HMNKMKAA_01630 9.5e-56 ropB K Transcriptional regulator
HMNKMKAA_01631 7.3e-212 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMNKMKAA_01632 8.7e-209 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HMNKMKAA_01633 0.0 yjbQ P TrkA C-terminal domain protein
HMNKMKAA_01634 3.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMNKMKAA_01635 9.2e-178 S Oxidoreductase family, NAD-binding Rossmann fold
HMNKMKAA_01636 9.5e-136
HMNKMKAA_01637 6.8e-136
HMNKMKAA_01638 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMNKMKAA_01639 8.4e-99 G Aldose 1-epimerase
HMNKMKAA_01640 1.8e-201 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMNKMKAA_01641 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMNKMKAA_01642 0.0 XK27_08315 M Sulfatase
HMNKMKAA_01643 1.6e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMNKMKAA_01644 9e-54
HMNKMKAA_01646 1.4e-258 pepC 3.4.22.40 E aminopeptidase
HMNKMKAA_01647 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMNKMKAA_01648 2.9e-301 oppA E ABC transporter, substratebinding protein
HMNKMKAA_01649 5e-309 oppA E ABC transporter, substratebinding protein
HMNKMKAA_01650 1.7e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMNKMKAA_01651 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMNKMKAA_01652 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMNKMKAA_01653 2.7e-199 oppD P Belongs to the ABC transporter superfamily
HMNKMKAA_01654 1.9e-175 oppF P Belongs to the ABC transporter superfamily
HMNKMKAA_01655 3e-256 pepC 3.4.22.40 E aminopeptidase
HMNKMKAA_01656 9e-69 hsp O Belongs to the small heat shock protein (HSP20) family
HMNKMKAA_01657 2.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMNKMKAA_01658 1.2e-112
HMNKMKAA_01660 7.8e-111 E Belongs to the SOS response-associated peptidase family
HMNKMKAA_01661 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMNKMKAA_01662 5.7e-88 comEB 3.5.4.12 F MafB19-like deaminase
HMNKMKAA_01663 1e-102 S TPM domain
HMNKMKAA_01664 9.1e-80 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMNKMKAA_01665 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMNKMKAA_01667 1.3e-112 V ABC-type multidrug transport system, ATPase and permease components
HMNKMKAA_01668 6.4e-134 KLT Protein kinase domain
HMNKMKAA_01669 1.7e-160 V ABC-type multidrug transport system, ATPase and permease components
HMNKMKAA_01670 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMNKMKAA_01671 9.6e-146 tatD L hydrolase, TatD family
HMNKMKAA_01672 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMNKMKAA_01673 2.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMNKMKAA_01674 1.2e-39 veg S Biofilm formation stimulator VEG
HMNKMKAA_01675 1.5e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HMNKMKAA_01676 5.7e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMNKMKAA_01677 5.3e-80
HMNKMKAA_01678 0.0 S SLAP domain
HMNKMKAA_01679 6.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMNKMKAA_01680 5.2e-170 2.7.1.2 GK ROK family
HMNKMKAA_01681 1.9e-43
HMNKMKAA_01682 5e-270 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMNKMKAA_01683 2e-68 S Domain of unknown function (DUF1934)
HMNKMKAA_01684 1.7e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMNKMKAA_01685 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMNKMKAA_01686 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMNKMKAA_01687 2.7e-75 K acetyltransferase
HMNKMKAA_01688 7.5e-285 pipD E Dipeptidase
HMNKMKAA_01689 2.2e-156 msmR K AraC-like ligand binding domain
HMNKMKAA_01690 1.1e-221 pbuX F xanthine permease
HMNKMKAA_01691 4.5e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMNKMKAA_01692 3e-07 K Helix-turn-helix
HMNKMKAA_01693 6.6e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMNKMKAA_01694 1.1e-49 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HMNKMKAA_01695 3.5e-183 arsB 1.20.4.1 P Sodium Bile acid symporter family
HMNKMKAA_01696 7e-71 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMNKMKAA_01697 3.8e-20
HMNKMKAA_01699 3.5e-19 D Ftsk spoiiie family protein
HMNKMKAA_01700 3.4e-15 D Ftsk spoiiie family protein
HMNKMKAA_01701 5e-29 S Replication initiation factor
HMNKMKAA_01702 2.3e-30 S Domain of unknown function (DUF3173)
HMNKMKAA_01703 1.2e-38 L Belongs to the 'phage' integrase family
HMNKMKAA_01704 4.1e-107 L Belongs to the 'phage' integrase family
HMNKMKAA_01706 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMNKMKAA_01707 0.0 3.2.1.18 GH33 M Rib/alpha-like repeat
HMNKMKAA_01710 7.9e-57 ps115 K Helix-turn-helix XRE-family like proteins
HMNKMKAA_01711 3.7e-19 yjdF S Protein of unknown function (DUF2992)
HMNKMKAA_01712 1.7e-98 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HMNKMKAA_01713 5.1e-59 hxlR K Transcriptional regulator, HxlR family
HMNKMKAA_01714 2.5e-197 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HMNKMKAA_01715 6.1e-96 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMNKMKAA_01716 1e-95
HMNKMKAA_01717 1.5e-145 yfeO P Voltage gated chloride channel
HMNKMKAA_01718 1.2e-166 5.3.3.2 C FMN-dependent dehydrogenase
HMNKMKAA_01719 2.8e-52
HMNKMKAA_01720 2.1e-42
HMNKMKAA_01721 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMNKMKAA_01722 4.9e-116 L Resolvase, N-terminal
HMNKMKAA_01723 3.8e-251 L Putative transposase DNA-binding domain
HMNKMKAA_01724 4.3e-297 ybeC E amino acid
HMNKMKAA_01725 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
HMNKMKAA_01726 1e-24
HMNKMKAA_01727 9.5e-26
HMNKMKAA_01728 2.5e-33
HMNKMKAA_01729 2.4e-53 S Enterocin A Immunity
HMNKMKAA_01730 8.8e-144 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HMNKMKAA_01731 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMNKMKAA_01732 8.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HMNKMKAA_01733 9.6e-121 K response regulator
HMNKMKAA_01734 0.0 V ABC transporter
HMNKMKAA_01735 8.1e-302 V ABC transporter, ATP-binding protein
HMNKMKAA_01737 1.1e-152 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HMNKMKAA_01738 9.5e-40 S RelB antitoxin
HMNKMKAA_01739 1.4e-50
HMNKMKAA_01740 5.6e-217 KQ helix_turn_helix, mercury resistance
HMNKMKAA_01741 5.9e-207 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMNKMKAA_01742 7.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMNKMKAA_01743 1.3e-116 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HMNKMKAA_01744 3.9e-176 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMNKMKAA_01745 9.8e-62
HMNKMKAA_01746 2.2e-52
HMNKMKAA_01748 1.4e-36 ropB K Helix-turn-helix domain
HMNKMKAA_01749 2.7e-56 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMNKMKAA_01750 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMNKMKAA_01751 0.0 copA 3.6.3.54 P P-type ATPase
HMNKMKAA_01752 6.9e-113 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HMNKMKAA_01753 1e-104
HMNKMKAA_01754 7e-248 EGP Sugar (and other) transporter
HMNKMKAA_01755 1.2e-18
HMNKMKAA_01756 5.6e-211
HMNKMKAA_01757 2.5e-47 S SLAP domain
HMNKMKAA_01758 3.8e-31
HMNKMKAA_01759 2.7e-22
HMNKMKAA_01760 1e-80
HMNKMKAA_01761 2.4e-30 yozG K Transcriptional regulator
HMNKMKAA_01762 4.8e-25
HMNKMKAA_01763 4.4e-68
HMNKMKAA_01764 3.6e-08
HMNKMKAA_01765 4.9e-29
HMNKMKAA_01766 9.2e-164 natA S ABC transporter, ATP-binding protein
HMNKMKAA_01767 9.8e-217 natB CP ABC-2 family transporter protein
HMNKMKAA_01768 1.8e-136 fruR K DeoR C terminal sensor domain
HMNKMKAA_01769 7.4e-169 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMNKMKAA_01770 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HMNKMKAA_01771 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HMNKMKAA_01772 3.4e-82 C Flavodoxin
HMNKMKAA_01773 0.0 uvrA3 L excinuclease ABC, A subunit
HMNKMKAA_01774 4.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HMNKMKAA_01775 2.1e-114 3.6.1.27 I Acid phosphatase homologues
HMNKMKAA_01776 2.3e-31 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMNKMKAA_01777 3.1e-87 gtcA S Teichoic acid glycosylation protein
HMNKMKAA_01778 4.1e-80 fld C Flavodoxin
HMNKMKAA_01779 6.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
HMNKMKAA_01780 3.6e-163 yihY S Belongs to the UPF0761 family
HMNKMKAA_01781 7.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMNKMKAA_01782 6.7e-215 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HMNKMKAA_01783 1.2e-214 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HMNKMKAA_01784 5.5e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HMNKMKAA_01785 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMNKMKAA_01786 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMNKMKAA_01787 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HMNKMKAA_01788 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMNKMKAA_01789 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMNKMKAA_01790 1.8e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMNKMKAA_01791 2.6e-35 yaaA S S4 domain protein YaaA
HMNKMKAA_01792 5.2e-39 S RES domain
HMNKMKAA_01793 1.6e-38
HMNKMKAA_01794 1.8e-57 cll
HMNKMKAA_01796 2.2e-30
HMNKMKAA_01797 6e-160 L Transposase
HMNKMKAA_01798 1.4e-36 L Transposase
HMNKMKAA_01799 1e-38 prrC S Protein conserved in bacteria
HMNKMKAA_01800 3.4e-158 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMNKMKAA_01801 1.7e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMNKMKAA_01802 4.5e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMNKMKAA_01803 2.3e-67 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMNKMKAA_01804 0.0 dnaK O Heat shock 70 kDa protein
HMNKMKAA_01805 5.8e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMNKMKAA_01809 6e-29 mloB K Putative ATP-dependent DNA helicase recG C-terminal
HMNKMKAA_01810 1.6e-248 lctP C L-lactate permease
HMNKMKAA_01811 2.3e-126 znuB U ABC 3 transport family
HMNKMKAA_01812 1e-108 fhuC P ABC transporter
HMNKMKAA_01813 5.1e-138 psaA P Belongs to the bacterial solute-binding protein 9 family
HMNKMKAA_01814 8.9e-44 K helix_turn_helix, Arsenical Resistance Operon Repressor
HMNKMKAA_01817 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
HMNKMKAA_01818 1.4e-36 S Cytochrome B5
HMNKMKAA_01819 2.3e-167 arbZ I Phosphate acyltransferases
HMNKMKAA_01820 2.5e-180 arbY M Glycosyl transferase family 8
HMNKMKAA_01821 3.4e-185 arbY M Glycosyl transferase family 8
HMNKMKAA_01822 8.6e-156 arbx M Glycosyl transferase family 8
HMNKMKAA_01823 1.2e-148 arbV 2.3.1.51 I Acyl-transferase
HMNKMKAA_01825 4.9e-34
HMNKMKAA_01827 4.8e-131 K response regulator
HMNKMKAA_01828 8.4e-305 vicK 2.7.13.3 T Histidine kinase
HMNKMKAA_01829 3.3e-258 yycH S YycH protein
HMNKMKAA_01830 3.4e-149 yycI S YycH protein
HMNKMKAA_01831 3.1e-147 vicX 3.1.26.11 S domain protein
HMNKMKAA_01832 3.3e-151 htrA 3.4.21.107 O serine protease
HMNKMKAA_01833 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMNKMKAA_01834 6.1e-33 G Peptidase_C39 like family
HMNKMKAA_01835 7.5e-163 M NlpC/P60 family
HMNKMKAA_01836 1.7e-91 G Peptidase_C39 like family
HMNKMKAA_01837 1.3e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HMNKMKAA_01838 1.3e-77 P Cobalt transport protein
HMNKMKAA_01839 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
HMNKMKAA_01840 5.1e-173 K helix_turn_helix, arabinose operon control protein
HMNKMKAA_01841 1e-159 htpX O Belongs to the peptidase M48B family
HMNKMKAA_01842 3e-96 lemA S LemA family
HMNKMKAA_01843 3.9e-196 ybiR P Citrate transporter
HMNKMKAA_01844 2.7e-70 S Iron-sulphur cluster biosynthesis
HMNKMKAA_01845 3.5e-308 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HMNKMKAA_01846 1.2e-17
HMNKMKAA_01847 6.9e-116
HMNKMKAA_01849 1e-216 ydaM M Glycosyl transferase
HMNKMKAA_01850 6.2e-178 G Glycosyl hydrolases family 8
HMNKMKAA_01851 1.4e-121 yfbR S HD containing hydrolase-like enzyme
HMNKMKAA_01852 1.9e-158 L HNH nucleases
HMNKMKAA_01853 2.6e-85 S Protein of unknown function (DUF805)
HMNKMKAA_01854 4e-136 glnQ E ABC transporter, ATP-binding protein
HMNKMKAA_01855 1.3e-290 glnP P ABC transporter permease
HMNKMKAA_01856 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HMNKMKAA_01857 2e-64 yeaO S Protein of unknown function, DUF488
HMNKMKAA_01858 9.6e-125 terC P Integral membrane protein TerC family
HMNKMKAA_01859 1.6e-91 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HMNKMKAA_01860 3.8e-133 cobB K SIR2 family
HMNKMKAA_01861 9.3e-86
HMNKMKAA_01862 1.3e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMNKMKAA_01863 1e-181 S Alpha/beta hydrolase of unknown function (DUF915)
HMNKMKAA_01864 9.7e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMNKMKAA_01865 2e-140 ypuA S Protein of unknown function (DUF1002)
HMNKMKAA_01866 2.8e-151 epsV 2.7.8.12 S glycosyl transferase family 2
HMNKMKAA_01867 1.3e-119 S Alpha/beta hydrolase family
HMNKMKAA_01868 2.1e-80 K Helix-turn-helix domain
HMNKMKAA_01870 8.3e-216 EGP Major Facilitator Superfamily
HMNKMKAA_01871 8.5e-139 noxC 1.5.1.39 C coenzyme F420-1:gamma-L-glutamate ligase activity
HMNKMKAA_01872 2.6e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMNKMKAA_01873 2.4e-124 luxT K Bacterial regulatory proteins, tetR family
HMNKMKAA_01874 2.8e-135
HMNKMKAA_01875 1.3e-258 glnPH2 P ABC transporter permease
HMNKMKAA_01876 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMNKMKAA_01877 1.4e-223 S Cysteine-rich secretory protein family
HMNKMKAA_01878 1.8e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMNKMKAA_01879 3.6e-113
HMNKMKAA_01880 1.1e-201 yibE S overlaps another CDS with the same product name
HMNKMKAA_01881 3.4e-130 yibF S overlaps another CDS with the same product name
HMNKMKAA_01882 3.8e-134 I alpha/beta hydrolase fold
HMNKMKAA_01883 0.0 G Belongs to the glycosyl hydrolase 31 family
HMNKMKAA_01884 2.7e-216 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMNKMKAA_01885 2.6e-274 S Archaea bacterial proteins of unknown function
HMNKMKAA_01886 2.3e-08
HMNKMKAA_01887 3.6e-90 ntd 2.4.2.6 F Nucleoside
HMNKMKAA_01888 2.7e-88 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMNKMKAA_01889 9.8e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HMNKMKAA_01890 5.2e-84 uspA T universal stress protein
HMNKMKAA_01891 4.1e-151 phnD P Phosphonate ABC transporter
HMNKMKAA_01892 4.1e-136 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HMNKMKAA_01893 8.8e-118 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HMNKMKAA_01894 6.4e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HMNKMKAA_01895 2.1e-105 tag 3.2.2.20 L glycosylase
HMNKMKAA_01896 1.5e-83
HMNKMKAA_01897 3.8e-273 S Calcineurin-like phosphoesterase
HMNKMKAA_01898 0.0 asnB 6.3.5.4 E Asparagine synthase
HMNKMKAA_01899 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
HMNKMKAA_01900 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMNKMKAA_01901 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMNKMKAA_01902 1.4e-102 S Iron-sulfur cluster assembly protein
HMNKMKAA_01903 4.9e-229 XK27_04775 S PAS domain
HMNKMKAA_01904 1.6e-211 yttB EGP Major facilitator Superfamily
HMNKMKAA_01905 0.0 pepO 3.4.24.71 O Peptidase family M13
HMNKMKAA_01906 0.0 kup P Transport of potassium into the cell
HMNKMKAA_01907 1.2e-73
HMNKMKAA_01908 1e-66 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMNKMKAA_01909 3.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMNKMKAA_01910 5.9e-45
HMNKMKAA_01912 7.2e-22 yifK E Amino acid permease
HMNKMKAA_01913 8.6e-233 cycA E Amino acid permease
HMNKMKAA_01914 1.6e-114 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMNKMKAA_01915 4.6e-118 V ABC transporter transmembrane region
HMNKMKAA_01916 6.5e-73 KLT serine threonine protein kinase
HMNKMKAA_01917 9.3e-80 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
HMNKMKAA_01918 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMNKMKAA_01919 8.1e-112 srtA 3.4.22.70 M sortase family
HMNKMKAA_01920 2.8e-304 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMNKMKAA_01921 3.3e-243 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HMNKMKAA_01924 2.8e-26 prrC S Protein conserved in bacteria
HMNKMKAA_01925 1.7e-09 prrC
HMNKMKAA_01926 1.9e-89 glf 5.4.99.9 M UDP-galactopyranose mutase
HMNKMKAA_01927 3.9e-257 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HMNKMKAA_01930 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
HMNKMKAA_01931 1.9e-153 spo0J K Belongs to the ParB family
HMNKMKAA_01932 3.4e-138 soj D Sporulation initiation inhibitor
HMNKMKAA_01933 8.6e-148 noc K Belongs to the ParB family
HMNKMKAA_01934 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HMNKMKAA_01935 3e-53 cvpA S Colicin V production protein
HMNKMKAA_01936 2e-91 2.7.7.7, 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HMNKMKAA_01937 2.1e-293 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HMNKMKAA_01938 9.9e-59 srtA 3.4.22.70 M Sortase family
HMNKMKAA_01939 4.2e-116
HMNKMKAA_01940 2.1e-216 yifK E Amino acid permease
HMNKMKAA_01941 4.1e-138 puuD S peptidase C26
HMNKMKAA_01942 3.9e-230 steT_1 E amino acid
HMNKMKAA_01943 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMNKMKAA_01944 1.6e-71 yqeY S YqeY-like protein
HMNKMKAA_01945 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
HMNKMKAA_01946 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMNKMKAA_01947 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMNKMKAA_01948 3.6e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HMNKMKAA_01949 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMNKMKAA_01950 3.2e-33 ykzG S Belongs to the UPF0356 family
HMNKMKAA_01954 6.4e-79 K LytTr DNA-binding domain
HMNKMKAA_01955 3e-77 2.7.13.3 T GHKL domain
HMNKMKAA_01956 4.8e-296 L Nuclease-related domain
HMNKMKAA_01957 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMNKMKAA_01958 8.3e-106 S Repeat protein
HMNKMKAA_01959 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HMNKMKAA_01960 4.6e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMNKMKAA_01961 2.2e-57 XK27_04120 S Putative amino acid metabolism
HMNKMKAA_01962 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
HMNKMKAA_01963 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMNKMKAA_01964 2.1e-38
HMNKMKAA_01965 9.8e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HMNKMKAA_01966 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
HMNKMKAA_01967 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMNKMKAA_01968 2.8e-74 gpsB D DivIVA domain protein
HMNKMKAA_01969 7.4e-149 ylmH S S4 domain protein
HMNKMKAA_01970 1.7e-45 yggT S YGGT family
HMNKMKAA_01971 1.5e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMNKMKAA_01972 1.6e-204 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMNKMKAA_01973 7.7e-247 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMNKMKAA_01974 5.3e-153 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMNKMKAA_01975 4.4e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMNKMKAA_01976 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMNKMKAA_01977 1.1e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMNKMKAA_01978 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HMNKMKAA_01979 1.8e-54 ftsL D Cell division protein FtsL
HMNKMKAA_01980 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMNKMKAA_01981 6.3e-78 mraZ K Belongs to the MraZ family
HMNKMKAA_01982 6.4e-54 S Protein of unknown function (DUF3397)
HMNKMKAA_01984 6e-94 mreD
HMNKMKAA_01985 8.8e-148 mreC M Involved in formation and maintenance of cell shape
HMNKMKAA_01986 1.8e-176 mreB D cell shape determining protein MreB
HMNKMKAA_01987 2.3e-108 radC L DNA repair protein
HMNKMKAA_01988 2e-126 S Haloacid dehalogenase-like hydrolase
HMNKMKAA_01989 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMNKMKAA_01990 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMNKMKAA_01991 7.9e-91 hchA S DJ-1/PfpI family
HMNKMKAA_01992 1.5e-129 C NADH:flavin oxidoreductase / NADH oxidase family
HMNKMKAA_01993 4.9e-21 K helix_turn_helix, Arsenical Resistance Operon Repressor
HMNKMKAA_01994 1.1e-23 S Uncharacterised protein family (UPF0236)
HMNKMKAA_01995 3.4e-74 K Helix-turn-helix domain
HMNKMKAA_01996 3.1e-170
HMNKMKAA_01997 0.0 3.6.3.8 P P-type ATPase
HMNKMKAA_01999 2.9e-44
HMNKMKAA_02000 9.8e-94 S Protein of unknown function (DUF3990)
HMNKMKAA_02001 4.7e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HMNKMKAA_02002 8.3e-67 2.4.1.83 GT2 S GtrA-like protein
HMNKMKAA_02003 9.1e-28 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMNKMKAA_02004 1.9e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMNKMKAA_02005 3.8e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HMNKMKAA_02006 1.3e-143
HMNKMKAA_02007 1.1e-134 K Helix-turn-helix XRE-family like proteins
HMNKMKAA_02008 4.7e-111
HMNKMKAA_02013 3.1e-21
HMNKMKAA_02014 2.5e-33 gepA S Protein of unknown function (DUF4065)
HMNKMKAA_02015 1.3e-61
HMNKMKAA_02016 3.8e-81 K Helix-turn-helix XRE-family like proteins
HMNKMKAA_02018 9.7e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMNKMKAA_02019 1.8e-215 iscS2 2.8.1.7 E Aminotransferase class V
HMNKMKAA_02020 3.1e-293 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMNKMKAA_02021 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMNKMKAA_02022 9.9e-85 yueI S Protein of unknown function (DUF1694)
HMNKMKAA_02023 7.4e-239 rarA L recombination factor protein RarA
HMNKMKAA_02024 2.4e-38
HMNKMKAA_02025 9.8e-77 usp6 T universal stress protein
HMNKMKAA_02026 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMNKMKAA_02027 7.8e-112 L Transposase
HMNKMKAA_02028 1.2e-216 rodA D Belongs to the SEDS family
HMNKMKAA_02029 1.5e-33 S Protein of unknown function (DUF2969)
HMNKMKAA_02030 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HMNKMKAA_02031 2.5e-178 mbl D Cell shape determining protein MreB Mrl
HMNKMKAA_02032 6.9e-31 ywzB S Protein of unknown function (DUF1146)
HMNKMKAA_02033 7.6e-71 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMNKMKAA_02034 8.1e-255 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMNKMKAA_02035 1.7e-168 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMNKMKAA_02036 5.3e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMNKMKAA_02037 3.7e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMNKMKAA_02038 6.6e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMNKMKAA_02039 6.6e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMNKMKAA_02040 5.1e-125 atpB C it plays a direct role in the translocation of protons across the membrane
HMNKMKAA_02041 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMNKMKAA_02042 1.4e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMNKMKAA_02043 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMNKMKAA_02044 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMNKMKAA_02045 1.3e-113 tdk 2.7.1.21 F thymidine kinase
HMNKMKAA_02046 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HMNKMKAA_02047 7.2e-137 sip L Belongs to the 'phage' integrase family
HMNKMKAA_02048 2.3e-17 K transcriptional
HMNKMKAA_02049 1.9e-24
HMNKMKAA_02050 2.6e-25
HMNKMKAA_02054 3.9e-22
HMNKMKAA_02055 5.7e-50 L Replication initiation factor
HMNKMKAA_02056 1.3e-67 L RelB antitoxin
HMNKMKAA_02057 6.5e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HMNKMKAA_02058 5.9e-47 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
HMNKMKAA_02059 4.5e-149 K Helix-turn-helix XRE-family like proteins
HMNKMKAA_02060 3.2e-272 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HMNKMKAA_02061 3e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMNKMKAA_02062 1.2e-135 XK27_01040 S Protein of unknown function (DUF1129)
HMNKMKAA_02063 4.4e-175 L Bifunctional protein
HMNKMKAA_02064 7.5e-233 L COG3547 Transposase and inactivated derivatives
HMNKMKAA_02065 4.3e-247 L Transposase
HMNKMKAA_02066 1.1e-228 L Transposase
HMNKMKAA_02067 1.5e-211 tnpB L Putative transposase DNA-binding domain
HMNKMKAA_02068 1.9e-58 S CAAX amino terminal protease
HMNKMKAA_02069 9.6e-32 L Transposase
HMNKMKAA_02070 8.3e-165 L Transposase
HMNKMKAA_02071 2.7e-155 UW LPXTG-motif cell wall anchor domain protein
HMNKMKAA_02072 9.9e-88 UW LPXTG-motif cell wall anchor domain protein
HMNKMKAA_02073 1.6e-44 UW LPXTG-motif cell wall anchor domain protein
HMNKMKAA_02074 5.3e-24 UW LPXTG-motif cell wall anchor domain protein
HMNKMKAA_02075 1.8e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMNKMKAA_02076 4.1e-98 J Acetyltransferase (GNAT) domain
HMNKMKAA_02077 1.8e-110 yjbF S SNARE associated Golgi protein
HMNKMKAA_02078 6.5e-153 I alpha/beta hydrolase fold
HMNKMKAA_02079 8.3e-128 hipB K Helix-turn-helix
HMNKMKAA_02080 2.4e-92 F Nucleoside 2-deoxyribosyltransferase
HMNKMKAA_02081 1.9e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HMNKMKAA_02082 5.5e-165
HMNKMKAA_02083 0.0 ydgH S MMPL family
HMNKMKAA_02084 8.7e-99 yobS K Bacterial regulatory proteins, tetR family
HMNKMKAA_02085 2.2e-147 3.5.2.6 V Beta-lactamase enzyme family
HMNKMKAA_02086 1.8e-154 corA P CorA-like Mg2+ transporter protein
HMNKMKAA_02087 2.5e-239 G Bacterial extracellular solute-binding protein
HMNKMKAA_02088 7.1e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HMNKMKAA_02089 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
HMNKMKAA_02090 7.3e-158 gtsB P ABC-type sugar transport systems, permease components
HMNKMKAA_02091 1.9e-203 malK P ATPases associated with a variety of cellular activities
HMNKMKAA_02092 2.7e-282 pipD E Dipeptidase
HMNKMKAA_02093 1.9e-158 endA F DNA RNA non-specific endonuclease
HMNKMKAA_02094 3.2e-183 dnaQ 2.7.7.7 L EXOIII
HMNKMKAA_02095 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMNKMKAA_02096 3e-116 yviA S Protein of unknown function (DUF421)
HMNKMKAA_02097 1.1e-72 S Protein of unknown function (DUF3290)
HMNKMKAA_02098 7.6e-140 pnuC H nicotinamide mononucleotide transporter
HMNKMKAA_02099 3.9e-13
HMNKMKAA_02100 2.5e-130 S PAS domain
HMNKMKAA_02101 3.1e-279 V ABC transporter transmembrane region
HMNKMKAA_02102 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HMNKMKAA_02103 5.3e-130 T Transcriptional regulatory protein, C terminal
HMNKMKAA_02104 1.3e-246 T GHKL domain
HMNKMKAA_02105 1.1e-87 S Peptidase propeptide and YPEB domain
HMNKMKAA_02106 2.6e-101 S Peptidase propeptide and YPEB domain
HMNKMKAA_02107 3.1e-39 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HMNKMKAA_02108 1.1e-47 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HMNKMKAA_02109 2.1e-76 yybA 2.3.1.57 K Transcriptional regulator
HMNKMKAA_02110 7.5e-241 V ABC transporter transmembrane region
HMNKMKAA_02111 0.0 oppA3 E ABC transporter, substratebinding protein
HMNKMKAA_02112 9.9e-62 ypaA S Protein of unknown function (DUF1304)
HMNKMKAA_02113 1.3e-50 S Peptidase propeptide and YPEB domain
HMNKMKAA_02114 4.4e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMNKMKAA_02115 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
HMNKMKAA_02116 4.9e-99 E GDSL-like Lipase/Acylhydrolase
HMNKMKAA_02117 3.7e-73 yjcF S Acetyltransferase (GNAT) domain
HMNKMKAA_02118 3.9e-145 aatB ET ABC transporter substrate-binding protein
HMNKMKAA_02119 1.6e-106 glnQ 3.6.3.21 E ABC transporter
HMNKMKAA_02120 3.2e-110 glnP P ABC transporter permease
HMNKMKAA_02121 0.0 helD 3.6.4.12 L DNA helicase
HMNKMKAA_02122 2.7e-124 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HMNKMKAA_02123 1.4e-126 pgm3 G Phosphoglycerate mutase family
HMNKMKAA_02124 5.9e-241 S response to antibiotic
HMNKMKAA_02125 2.9e-125
HMNKMKAA_02126 0.0 3.6.3.8 P P-type ATPase
HMNKMKAA_02127 5.7e-65 2.7.1.191 G PTS system fructose IIA component
HMNKMKAA_02128 2.1e-42
HMNKMKAA_02129 7.7e-09
HMNKMKAA_02130 4.2e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
HMNKMKAA_02131 1.8e-136 glvR K Helix-turn-helix domain, rpiR family
HMNKMKAA_02132 1.7e-267 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HMNKMKAA_02133 4e-153
HMNKMKAA_02134 8.6e-24
HMNKMKAA_02135 2.9e-88 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMNKMKAA_02136 4.2e-106 3.2.2.20 K acetyltransferase
HMNKMKAA_02138 3.3e-08 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HMNKMKAA_02139 1.9e-72 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HMNKMKAA_02140 0.0 O Belongs to the peptidase S8 family
HMNKMKAA_02141 2.3e-198 L Transposase
HMNKMKAA_02142 9.1e-139 L COG2826 Transposase and inactivated derivatives, IS30 family
HMNKMKAA_02143 4.3e-102 S Protein of unknown function (DUF1211)
HMNKMKAA_02145 5.7e-139 L An automated process has identified a potential problem with this gene model
HMNKMKAA_02146 1.1e-197 L Transposase and inactivated derivatives, IS30 family
HMNKMKAA_02147 5.6e-86
HMNKMKAA_02149 5.1e-81 L transposase, IS605 OrfB family
HMNKMKAA_02150 1.1e-136 recO L Involved in DNA repair and RecF pathway recombination
HMNKMKAA_02151 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMNKMKAA_02152 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMNKMKAA_02153 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMNKMKAA_02154 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMNKMKAA_02155 8e-128 S Peptidase family M23
HMNKMKAA_02156 1.4e-80 mutT 3.6.1.55 F NUDIX domain
HMNKMKAA_02157 1.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMNKMKAA_02158 8.5e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMNKMKAA_02159 2e-241 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMNKMKAA_02160 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
HMNKMKAA_02161 6.2e-123 skfE V ATPases associated with a variety of cellular activities
HMNKMKAA_02162 6.2e-122
HMNKMKAA_02163 3e-105
HMNKMKAA_02164 3.1e-110
HMNKMKAA_02165 4.3e-39 ybjQ S Belongs to the UPF0145 family
HMNKMKAA_02166 3.8e-27
HMNKMKAA_02167 2.5e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMNKMKAA_02168 1.8e-144
HMNKMKAA_02169 4.3e-169
HMNKMKAA_02170 1.4e-264 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HMNKMKAA_02171 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HMNKMKAA_02172 8.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMNKMKAA_02173 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HMNKMKAA_02174 3.7e-179 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HMNKMKAA_02175 1.3e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HMNKMKAA_02176 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMNKMKAA_02177 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMNKMKAA_02178 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMNKMKAA_02179 8.3e-90 ypmB S Protein conserved in bacteria
HMNKMKAA_02180 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HMNKMKAA_02181 1.3e-114 dnaD L DnaD domain protein
HMNKMKAA_02182 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMNKMKAA_02183 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HMNKMKAA_02184 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMNKMKAA_02185 1e-107 ypsA S Belongs to the UPF0398 family
HMNKMKAA_02186 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMNKMKAA_02187 1.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMNKMKAA_02188 1.4e-242 cpdA S Calcineurin-like phosphoesterase
HMNKMKAA_02189 3.4e-79
HMNKMKAA_02190 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
HMNKMKAA_02191 1.4e-34
HMNKMKAA_02192 2.4e-62
HMNKMKAA_02195 1.4e-117
HMNKMKAA_02196 4.5e-105 pncA Q Isochorismatase family
HMNKMKAA_02197 1.7e-36
HMNKMKAA_02198 0.0 snf 2.7.11.1 KL domain protein
HMNKMKAA_02199 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMNKMKAA_02200 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMNKMKAA_02201 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMNKMKAA_02202 7.3e-183 K Transcriptional regulator
HMNKMKAA_02203 4.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
HMNKMKAA_02204 7.1e-112 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMNKMKAA_02205 4e-57 K Helix-turn-helix domain
HMNKMKAA_02206 2.7e-123 yoaK S Protein of unknown function (DUF1275)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)