ORF_ID e_value Gene_name EC_number CAZy COGs Description
PGHLFOJI_00002 2.5e-83 K GNAT family
PGHLFOJI_00003 1.2e-121 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PGHLFOJI_00004 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
PGHLFOJI_00005 6.3e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PGHLFOJI_00006 7.4e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PGHLFOJI_00008 3.6e-57
PGHLFOJI_00010 1.1e-06
PGHLFOJI_00011 1.8e-78 K Winged helix DNA-binding domain
PGHLFOJI_00012 0.0 lmrA V ABC transporter, ATP-binding protein
PGHLFOJI_00013 0.0 yfiC V ABC transporter
PGHLFOJI_00014 9.7e-194 ampC V Beta-lactamase
PGHLFOJI_00015 4e-40 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGHLFOJI_00016 2e-227 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGHLFOJI_00017 2.8e-48
PGHLFOJI_00018 3.4e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
PGHLFOJI_00019 7.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
PGHLFOJI_00020 3.2e-109 tdk 2.7.1.21 F thymidine kinase
PGHLFOJI_00021 2.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PGHLFOJI_00022 6.5e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PGHLFOJI_00023 2.3e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PGHLFOJI_00024 1.6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PGHLFOJI_00025 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PGHLFOJI_00026 2.9e-183 yibE S overlaps another CDS with the same product name
PGHLFOJI_00027 1.7e-121 yibF S overlaps another CDS with the same product name
PGHLFOJI_00028 5.4e-218 pyrP F Permease
PGHLFOJI_00029 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
PGHLFOJI_00030 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGHLFOJI_00031 1.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PGHLFOJI_00032 7.4e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGHLFOJI_00033 1.4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PGHLFOJI_00034 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PGHLFOJI_00035 4.4e-253 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PGHLFOJI_00036 6.4e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PGHLFOJI_00037 2.8e-29 S Protein of unknown function (DUF1146)
PGHLFOJI_00038 1.8e-218 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
PGHLFOJI_00039 7.7e-183 mbl D Cell shape determining protein MreB Mrl
PGHLFOJI_00040 7.9e-32 S Protein of unknown function (DUF2969)
PGHLFOJI_00041 5.8e-222 rodA D Belongs to the SEDS family
PGHLFOJI_00043 5.3e-181 S Protein of unknown function (DUF2785)
PGHLFOJI_00044 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PGHLFOJI_00045 2.9e-151 2.3.1.19 K Helix-turn-helix XRE-family like proteins
PGHLFOJI_00046 6.8e-81 usp6 T universal stress protein
PGHLFOJI_00048 5.8e-236 rarA L recombination factor protein RarA
PGHLFOJI_00049 1.5e-85 yueI S Protein of unknown function (DUF1694)
PGHLFOJI_00050 3.3e-76 4.4.1.5 E Glyoxalase
PGHLFOJI_00051 2e-132 S Membrane
PGHLFOJI_00052 4.6e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGHLFOJI_00053 1.3e-11 S YjcQ protein
PGHLFOJI_00055 3.9e-164 L Belongs to the 'phage' integrase family
PGHLFOJI_00056 1.6e-14 L nuclease
PGHLFOJI_00057 1.1e-12
PGHLFOJI_00058 1.1e-25 xkdA E Zn peptidase
PGHLFOJI_00059 7.1e-18 ps115 K Helix-turn-helix XRE-family like proteins
PGHLFOJI_00061 1.6e-132 S DNA binding
PGHLFOJI_00066 1.4e-10 S Domain of unknown function (DUF771)
PGHLFOJI_00068 8.6e-31 S Siphovirus Gp157
PGHLFOJI_00069 3.2e-92 S AAA domain
PGHLFOJI_00070 3e-179 res L Helicase C-terminal domain protein
PGHLFOJI_00071 2.5e-55 S Protein of unknown function (DUF669)
PGHLFOJI_00072 0.0 S Phage plasmid primase, P4
PGHLFOJI_00073 4.6e-47 S VRR_NUC
PGHLFOJI_00078 7.2e-22
PGHLFOJI_00079 3e-99 C Domain of unknown function (DUF4145)
PGHLFOJI_00080 1.2e-148 S HNH endonuclease
PGHLFOJI_00081 7.4e-77 S Phage terminase, small subunit
PGHLFOJI_00082 0.0 S Phage Terminase
PGHLFOJI_00084 1.7e-240 S Phage portal protein
PGHLFOJI_00085 1.6e-40 pi136 S Caudovirus prohead serine protease
PGHLFOJI_00086 2.8e-194 S peptidase activity
PGHLFOJI_00087 1.1e-44 S Phage gp6-like head-tail connector protein
PGHLFOJI_00088 2.9e-30 S Phage head-tail joining protein
PGHLFOJI_00089 1.1e-33 S Bacteriophage HK97-gp10, putative tail-component
PGHLFOJI_00090 1.8e-42
PGHLFOJI_00091 6e-106 S Pfam:Phage_TTP_1
PGHLFOJI_00092 9.7e-13
PGHLFOJI_00093 0.0 S peptidoglycan catabolic process
PGHLFOJI_00094 4.9e-151 S Phage tail protein
PGHLFOJI_00095 1.4e-114 S Peptidase family M23
PGHLFOJI_00096 4.2e-36 spoIVFA GT2,GT4 D peptidase
PGHLFOJI_00099 7.1e-30 S GDSL-like Lipase/Acylhydrolase
PGHLFOJI_00100 5.3e-60
PGHLFOJI_00101 2.4e-07
PGHLFOJI_00104 2.1e-20 S Bacteriophage holin of superfamily 6 (Holin_LLH)
PGHLFOJI_00105 5.8e-91 3.5.1.104 M hydrolase, family 25
PGHLFOJI_00106 2e-44 S Streptococcus thermophilus bacteriophage Gp111 protein
PGHLFOJI_00108 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PGHLFOJI_00109 3.5e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PGHLFOJI_00110 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
PGHLFOJI_00111 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGHLFOJI_00112 1.9e-46 L Transposase
PGHLFOJI_00113 2.5e-92 L hmm pf00665
PGHLFOJI_00114 1.8e-36 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PGHLFOJI_00115 2.4e-216 G PTS system sugar-specific permease component
PGHLFOJI_00116 3.8e-57 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PGHLFOJI_00117 1.7e-11 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PGHLFOJI_00118 7.5e-155 manR K PRD domain
PGHLFOJI_00119 5e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGHLFOJI_00120 0.0 L Helicase C-terminal domain protein
PGHLFOJI_00121 1.6e-54 S MazG-like family
PGHLFOJI_00122 4.7e-108 lssY 3.6.1.27 I Acid phosphatase homologues
PGHLFOJI_00123 7.2e-197 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PGHLFOJI_00124 1.3e-96
PGHLFOJI_00125 1.7e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PGHLFOJI_00126 3.7e-168 ponA V Beta-lactamase enzyme family
PGHLFOJI_00127 6.2e-266 yjeM E Amino Acid
PGHLFOJI_00129 2.1e-111
PGHLFOJI_00130 6.8e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
PGHLFOJI_00131 3.2e-164 K LysR substrate binding domain
PGHLFOJI_00132 1.9e-261 S Uncharacterized protein conserved in bacteria (DUF2252)
PGHLFOJI_00133 2e-301 scrB 3.2.1.26 GH32 G invertase
PGHLFOJI_00134 2.3e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
PGHLFOJI_00135 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
PGHLFOJI_00136 3.6e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGHLFOJI_00137 2e-13 nlhH_1 I acetylesterase activity
PGHLFOJI_00138 2e-32 nlhH_1 I Carboxylesterase family
PGHLFOJI_00139 6.2e-31 mleR K LysR family
PGHLFOJI_00140 4.2e-231 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PGHLFOJI_00141 6e-183 XK27_09615 S reductase
PGHLFOJI_00142 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
PGHLFOJI_00143 6.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PGHLFOJI_00144 2e-218 frdC 1.3.5.4 C FAD binding domain
PGHLFOJI_00145 1.7e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PGHLFOJI_00146 1.6e-231 P Sodium:sulfate symporter transmembrane region
PGHLFOJI_00147 7.2e-175 citR K sugar-binding domain protein
PGHLFOJI_00148 7.6e-211 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
PGHLFOJI_00149 7.3e-197 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PGHLFOJI_00150 5.7e-46 citD C Covalent carrier of the coenzyme of citrate lyase
PGHLFOJI_00151 4.2e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
PGHLFOJI_00152 1.7e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
PGHLFOJI_00153 5.6e-256 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PGHLFOJI_00154 9.9e-146 ydjP I Alpha/beta hydrolase family
PGHLFOJI_00155 1.7e-109 L PFAM Integrase catalytic region
PGHLFOJI_00157 1.4e-52 crtB 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
PGHLFOJI_00158 3.8e-48 G Major Facilitator
PGHLFOJI_00159 6.2e-10 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PGHLFOJI_00160 5.3e-17 mleP3 S Membrane transport protein
PGHLFOJI_00162 3.6e-76 tlpA2 L Transposase IS200 like
PGHLFOJI_00164 2.4e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PGHLFOJI_00165 4.8e-22 L hmm pf00665
PGHLFOJI_00166 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
PGHLFOJI_00167 6.3e-145 L 4.5 Transposon and IS
PGHLFOJI_00168 3.3e-29 L Transposase
PGHLFOJI_00169 1.2e-123 S Membrane
PGHLFOJI_00170 3.2e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PGHLFOJI_00171 0.0 pepF E oligoendopeptidase F
PGHLFOJI_00172 1.9e-178 K helix_turn _helix lactose operon repressor
PGHLFOJI_00173 6.7e-139 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHLFOJI_00174 1.9e-77 K AsnC family
PGHLFOJI_00175 1.4e-81 uspA T universal stress protein
PGHLFOJI_00176 9.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PGHLFOJI_00177 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PGHLFOJI_00178 2.3e-207 yeaN P Transporter, major facilitator family protein
PGHLFOJI_00179 4.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
PGHLFOJI_00180 2.4e-83 nrdI F Belongs to the NrdI family
PGHLFOJI_00181 3.6e-252 yhdP S Transporter associated domain
PGHLFOJI_00182 5.2e-90 GM epimerase
PGHLFOJI_00183 3.4e-86 M1-874 K Domain of unknown function (DUF1836)
PGHLFOJI_00184 1.7e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
PGHLFOJI_00185 7.8e-266 pipD E Dipeptidase
PGHLFOJI_00186 3.2e-130
PGHLFOJI_00187 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PGHLFOJI_00188 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
PGHLFOJI_00189 7.4e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
PGHLFOJI_00190 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PGHLFOJI_00192 4.1e-281 yjeM E Amino Acid
PGHLFOJI_00193 1.2e-188 K helix_turn _helix lactose operon repressor
PGHLFOJI_00194 9.2e-259 G PTS system Galactitol-specific IIC component
PGHLFOJI_00195 3.2e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGHLFOJI_00196 1.1e-200 S Domain of unknown function (DUF4432)
PGHLFOJI_00197 9.8e-115 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PGHLFOJI_00198 3.7e-171 deoR K sugar-binding domain protein
PGHLFOJI_00199 2.2e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGHLFOJI_00200 1.6e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PGHLFOJI_00201 3e-243 fucP G Major Facilitator Superfamily
PGHLFOJI_00202 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PGHLFOJI_00203 8.3e-13 tlpA2 L Transposase IS200 like
PGHLFOJI_00205 4.4e-49 tnp L MULE transposase domain
PGHLFOJI_00206 2.8e-38 ykuJ S Protein of unknown function (DUF1797)
PGHLFOJI_00207 6.5e-182 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PGHLFOJI_00208 1.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
PGHLFOJI_00209 3.4e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PGHLFOJI_00210 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PGHLFOJI_00211 4.7e-39 ptsH G phosphocarrier protein HPR
PGHLFOJI_00213 0.0 clpE O Belongs to the ClpA ClpB family
PGHLFOJI_00214 6.4e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
PGHLFOJI_00215 4.1e-109 pncA Q Isochorismatase family
PGHLFOJI_00216 2e-266 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGHLFOJI_00217 1.7e-97 S Pfam:DUF3816
PGHLFOJI_00218 3.6e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
PGHLFOJI_00219 8.4e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGHLFOJI_00220 9.4e-161 EG EamA-like transporter family
PGHLFOJI_00221 2.7e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
PGHLFOJI_00222 5.5e-15
PGHLFOJI_00223 4.7e-157 V ABC transporter, ATP-binding protein
PGHLFOJI_00224 7.8e-64 gntR1 K Transcriptional regulator, GntR family
PGHLFOJI_00225 1.5e-172 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PGHLFOJI_00226 1.9e-88 S Bacterial membrane protein, YfhO
PGHLFOJI_00227 3.1e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
PGHLFOJI_00228 1.3e-95 M transferase activity, transferring glycosyl groups
PGHLFOJI_00229 7.7e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PGHLFOJI_00230 7.7e-164 ykoT GT2 M Glycosyl transferase family 2
PGHLFOJI_00231 1.3e-138 yueF S AI-2E family transporter
PGHLFOJI_00232 3.8e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PGHLFOJI_00233 1.1e-08
PGHLFOJI_00234 3e-64 M repeat protein
PGHLFOJI_00235 5.9e-61 3.2.1.96, 3.5.1.28 GH73 M repeat protein
PGHLFOJI_00237 3.7e-64 acmD M repeat protein
PGHLFOJI_00238 4e-73 S enterobacterial common antigen metabolic process
PGHLFOJI_00239 4.6e-202 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PGHLFOJI_00240 9.6e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
PGHLFOJI_00241 4.5e-45 M biosynthesis protein
PGHLFOJI_00242 1.2e-94 cps3F
PGHLFOJI_00243 3e-147 cps1D M Domain of unknown function (DUF4422)
PGHLFOJI_00244 1.1e-118 rfbP M Bacterial sugar transferase
PGHLFOJI_00245 1.4e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
PGHLFOJI_00246 1.3e-07
PGHLFOJI_00247 3.8e-31 S Protein of unknown function (DUF2922)
PGHLFOJI_00248 2.7e-139 yihY S Belongs to the UPF0761 family
PGHLFOJI_00249 1.9e-54 ydiI Q Thioesterase superfamily
PGHLFOJI_00250 5.3e-158 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PGHLFOJI_00251 3.4e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PGHLFOJI_00252 1.7e-218 G Transporter, major facilitator family protein
PGHLFOJI_00253 6.1e-207 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
PGHLFOJI_00254 1.5e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PGHLFOJI_00255 1.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PGHLFOJI_00256 2.5e-40 gcvR T Belongs to the UPF0237 family
PGHLFOJI_00257 9.3e-245 XK27_08635 S UPF0210 protein
PGHLFOJI_00258 1.1e-178 yobV1 K WYL domain
PGHLFOJI_00259 4.1e-68 S pyridoxamine 5-phosphate
PGHLFOJI_00260 1.3e-34
PGHLFOJI_00263 3.1e-62
PGHLFOJI_00264 6e-114 yicL EG EamA-like transporter family
PGHLFOJI_00265 2.5e-13 S Domain of unknown function (DUF4352)
PGHLFOJI_00266 2.6e-74 S Domain of unknown function (DUF4352)
PGHLFOJI_00267 0.0 1.3.5.4 C FAD binding domain
PGHLFOJI_00268 1.7e-168 K LysR substrate binding domain
PGHLFOJI_00269 4.1e-161 rssA S Phospholipase, patatin family
PGHLFOJI_00270 1.9e-214 phbA 2.3.1.9 I Belongs to the thiolase family
PGHLFOJI_00271 5.6e-179 S AI-2E family transporter
PGHLFOJI_00272 9.1e-125 S membrane transporter protein
PGHLFOJI_00273 1.4e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
PGHLFOJI_00274 1e-193 V Beta-lactamase
PGHLFOJI_00275 9.2e-228
PGHLFOJI_00277 6.3e-154 S Alpha/beta hydrolase of unknown function (DUF915)
PGHLFOJI_00278 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGHLFOJI_00279 2.2e-165 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PGHLFOJI_00280 1.2e-163 endA F DNA RNA non-specific endonuclease
PGHLFOJI_00281 2.7e-268 pipD E Dipeptidase
PGHLFOJI_00283 5.1e-254 yifK E Amino acid permease
PGHLFOJI_00285 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PGHLFOJI_00286 1.5e-236 N Uncharacterized conserved protein (DUF2075)
PGHLFOJI_00288 4.5e-79 ndk 2.7.4.6 F Belongs to the NDK family
PGHLFOJI_00289 2.2e-99 padR K Virulence activator alpha C-term
PGHLFOJI_00290 1.4e-93 padC Q Phenolic acid decarboxylase
PGHLFOJI_00292 7.3e-219 I transferase activity, transferring acyl groups other than amino-acyl groups
PGHLFOJI_00294 2.2e-44 L Transposase IS200 like
PGHLFOJI_00295 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
PGHLFOJI_00296 6.4e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PGHLFOJI_00297 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PGHLFOJI_00298 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PGHLFOJI_00299 1.2e-74 rplI J Binds to the 23S rRNA
PGHLFOJI_00300 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PGHLFOJI_00301 1.6e-208 lmrP E Major Facilitator Superfamily
PGHLFOJI_00302 1.2e-48
PGHLFOJI_00305 6.8e-130 K response regulator
PGHLFOJI_00306 0.0 vicK 2.7.13.3 T Histidine kinase
PGHLFOJI_00307 6.7e-240 yycH S YycH protein
PGHLFOJI_00308 8e-143 yycI S YycH protein
PGHLFOJI_00309 6e-154 vicX 3.1.26.11 S domain protein
PGHLFOJI_00310 3e-208 htrA 3.4.21.107 O serine protease
PGHLFOJI_00311 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PGHLFOJI_00312 5.7e-71 K Transcriptional regulator
PGHLFOJI_00313 3.2e-175 malR K Transcriptional regulator, LacI family
PGHLFOJI_00314 3e-251 malT G Major Facilitator
PGHLFOJI_00315 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PGHLFOJI_00316 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PGHLFOJI_00317 1.1e-110 ysdA CP transmembrane transport
PGHLFOJI_00318 4e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PGHLFOJI_00319 1.4e-183 D Alpha beta
PGHLFOJI_00320 4.1e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGHLFOJI_00321 6.1e-216 patA 2.6.1.1 E Aminotransferase
PGHLFOJI_00322 2.7e-35
PGHLFOJI_00323 0.0 clpL O associated with various cellular activities
PGHLFOJI_00324 8.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGHLFOJI_00325 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PGHLFOJI_00326 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PGHLFOJI_00327 2.6e-163 yvgN C Aldo keto reductase
PGHLFOJI_00328 1.4e-292 glpQ 3.1.4.46 C phosphodiesterase
PGHLFOJI_00329 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
PGHLFOJI_00330 1.7e-23
PGHLFOJI_00331 9.8e-129 K Transcriptional regulatory protein, C-terminal domain protein
PGHLFOJI_00332 5.1e-159 pstS P Phosphate
PGHLFOJI_00333 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
PGHLFOJI_00334 5.5e-153 pstA P Phosphate transport system permease protein PstA
PGHLFOJI_00335 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PGHLFOJI_00336 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
PGHLFOJI_00337 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PGHLFOJI_00338 3.5e-39 ylqC S Belongs to the UPF0109 family
PGHLFOJI_00339 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PGHLFOJI_00340 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PGHLFOJI_00341 1.7e-260 yfnA E Amino Acid
PGHLFOJI_00342 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PGHLFOJI_00343 2e-84 L Belongs to the 'phage' integrase family
PGHLFOJI_00344 4.7e-54 ycsI S Protein of unknown function (DUF1445)
PGHLFOJI_00345 5.6e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PGHLFOJI_00346 6.2e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PGHLFOJI_00347 2.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PGHLFOJI_00348 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PGHLFOJI_00349 4.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PGHLFOJI_00350 4.5e-154 yitU 3.1.3.104 S hydrolase
PGHLFOJI_00351 2.4e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PGHLFOJI_00352 9e-92 pstS P Phosphate
PGHLFOJI_00353 1.2e-97 pstC P probably responsible for the translocation of the substrate across the membrane
PGHLFOJI_00354 1.3e-103 pstA P Phosphate transport system permease protein PstA
PGHLFOJI_00355 3.6e-95 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGHLFOJI_00356 1.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PGHLFOJI_00357 4.3e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PGHLFOJI_00358 8.2e-182 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PGHLFOJI_00359 7.6e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PGHLFOJI_00360 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PGHLFOJI_00361 1.6e-88 ypmB S Protein conserved in bacteria
PGHLFOJI_00362 1.7e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PGHLFOJI_00363 4.7e-134 dnaD L DnaD domain protein
PGHLFOJI_00364 1.3e-121 ypuA S Protein of unknown function (DUF1002)
PGHLFOJI_00365 1.4e-192 C Aldo keto reductase family protein
PGHLFOJI_00366 3.7e-160 EG EamA-like transporter family
PGHLFOJI_00367 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PGHLFOJI_00368 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PGHLFOJI_00369 6e-111 ypsA S Belongs to the UPF0398 family
PGHLFOJI_00370 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PGHLFOJI_00371 1.5e-45 UW LPXTG-motif cell wall anchor domain protein
PGHLFOJI_00372 9.5e-38 UW LPXTG-motif cell wall anchor domain protein
PGHLFOJI_00373 4.8e-86 yrjD S LUD domain
PGHLFOJI_00374 1.8e-244 lutB C 4Fe-4S dicluster domain
PGHLFOJI_00375 5.6e-122 lutA C Cysteine-rich domain
PGHLFOJI_00376 6e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PGHLFOJI_00377 7.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PGHLFOJI_00378 2.4e-37 ynzC S UPF0291 protein
PGHLFOJI_00379 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
PGHLFOJI_00380 9.5e-115 plsC 2.3.1.51 I Acyltransferase
PGHLFOJI_00381 2.3e-136 yabB 2.1.1.223 L Methyltransferase small domain
PGHLFOJI_00382 2.3e-47 yazA L GIY-YIG catalytic domain protein
PGHLFOJI_00383 5e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
PGHLFOJI_00384 4.9e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PGHLFOJI_00385 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PGHLFOJI_00386 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PGHLFOJI_00387 1.3e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PGHLFOJI_00388 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
PGHLFOJI_00389 6.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PGHLFOJI_00390 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PGHLFOJI_00391 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGHLFOJI_00392 9.2e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
PGHLFOJI_00393 2.7e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
PGHLFOJI_00394 3.7e-208 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PGHLFOJI_00395 3e-110 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PGHLFOJI_00396 4.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PGHLFOJI_00397 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PGHLFOJI_00398 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
PGHLFOJI_00399 3.7e-224 nusA K Participates in both transcription termination and antitermination
PGHLFOJI_00400 1.4e-47 ylxR K Protein of unknown function (DUF448)
PGHLFOJI_00401 3.2e-50 ylxQ J ribosomal protein
PGHLFOJI_00402 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PGHLFOJI_00403 3.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PGHLFOJI_00404 6.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PGHLFOJI_00405 1.6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PGHLFOJI_00406 2.7e-247 EGP Major facilitator Superfamily
PGHLFOJI_00407 3.5e-29 L Helix-turn-helix domain
PGHLFOJI_00409 2.1e-90
PGHLFOJI_00410 6.5e-78 F Nucleoside 2-deoxyribosyltransferase
PGHLFOJI_00411 1.3e-182 scrR3 K Transcriptional regulator, LacI family
PGHLFOJI_00412 2.8e-12
PGHLFOJI_00413 2.4e-16 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PGHLFOJI_00414 1.1e-06 M domain protein
PGHLFOJI_00416 1.4e-12 S CHY zinc finger
PGHLFOJI_00418 0.0 asnB 6.3.5.4 E Aluminium induced protein
PGHLFOJI_00420 2.5e-145 L Transposase and inactivated derivatives
PGHLFOJI_00421 1e-188 EGP Major facilitator Superfamily
PGHLFOJI_00424 1.7e-42 S Bacterial transferase hexapeptide (six repeats)
PGHLFOJI_00425 1.1e-41 S Bacterial transferase hexapeptide (six repeats)
PGHLFOJI_00426 1.9e-118 IQ Enoyl-(Acyl carrier protein) reductase
PGHLFOJI_00427 2.8e-199 gldA 1.1.1.6 C dehydrogenase
PGHLFOJI_00428 4.5e-17 xre K Helix-turn-helix domain
PGHLFOJI_00429 2.1e-51 S Sugar efflux transporter for intercellular exchange
PGHLFOJI_00430 2e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
PGHLFOJI_00431 9e-22 S Protein conserved in bacteria
PGHLFOJI_00432 1.8e-98 ywrO S Flavodoxin-like fold
PGHLFOJI_00433 1.7e-41 K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PGHLFOJI_00434 2.5e-152 tesE Q hydratase
PGHLFOJI_00435 1.9e-186 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGHLFOJI_00436 3.6e-61 S Domain of unknown function (DUF4440)
PGHLFOJI_00437 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PGHLFOJI_00438 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PGHLFOJI_00439 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHLFOJI_00440 8.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PGHLFOJI_00441 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PGHLFOJI_00442 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PGHLFOJI_00443 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PGHLFOJI_00445 1.4e-41 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PGHLFOJI_00446 2.8e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
PGHLFOJI_00447 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PGHLFOJI_00448 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PGHLFOJI_00449 3.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PGHLFOJI_00450 1.7e-162 S Tetratricopeptide repeat
PGHLFOJI_00451 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGHLFOJI_00452 6.7e-243 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PGHLFOJI_00453 5.2e-241 yfnA E amino acid
PGHLFOJI_00454 6e-16 S NADPH-dependent FMN reductase
PGHLFOJI_00455 8.9e-31 S NADPH-dependent FMN reductase
PGHLFOJI_00457 2.6e-157 L Thioesterase-like superfamily
PGHLFOJI_00458 1.1e-50 lacA S transferase hexapeptide repeat
PGHLFOJI_00459 4.7e-260 argH 4.3.2.1 E argininosuccinate lyase
PGHLFOJI_00460 1.3e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PGHLFOJI_00461 1.4e-242 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGHLFOJI_00462 2.7e-64 L Transposase IS200 like
PGHLFOJI_00463 8.2e-173 L transposase, IS605 OrfB family
PGHLFOJI_00464 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PGHLFOJI_00465 4.9e-102 K Transcriptional regulator
PGHLFOJI_00466 3.9e-22 XK27_06785 V ABC transporter
PGHLFOJI_00467 7.2e-167 M Membrane
PGHLFOJI_00468 3.8e-52 S FMN_bind
PGHLFOJI_00469 0.0 yhcA V ABC transporter, ATP-binding protein
PGHLFOJI_00470 2.3e-122 bm3R1 K Bacterial regulatory proteins, tetR family
PGHLFOJI_00471 1.5e-231 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PGHLFOJI_00472 3.5e-49 ybjQ S Belongs to the UPF0145 family
PGHLFOJI_00473 2.5e-73 rocF 3.5.3.1, 3.5.3.11 E Arginase family
PGHLFOJI_00475 5.1e-173 1.3.1.9 S Nitronate monooxygenase
PGHLFOJI_00476 4.7e-54 K Helix-turn-helix domain
PGHLFOJI_00477 1.2e-105 S Domain of unknown function (DUF4767)
PGHLFOJI_00478 5.8e-113
PGHLFOJI_00480 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
PGHLFOJI_00481 0.0 norZ 1.7.2.5 P Cytochrome C and Quinol oxidase polypeptide I
PGHLFOJI_00482 5.7e-270 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PGHLFOJI_00483 9.2e-115 2.7.6.5 T Region found in RelA / SpoT proteins
PGHLFOJI_00484 8e-80 K response regulator
PGHLFOJI_00485 1.4e-130 sptS 2.7.13.3 T Histidine kinase
PGHLFOJI_00486 8.2e-127 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PGHLFOJI_00487 1.7e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PGHLFOJI_00488 1.5e-135 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
PGHLFOJI_00489 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PGHLFOJI_00490 5.5e-245 glpT G Major Facilitator Superfamily
PGHLFOJI_00491 9.7e-130 qmcA O prohibitin homologues
PGHLFOJI_00493 3.1e-75 uspA T universal stress protein
PGHLFOJI_00494 2.1e-59
PGHLFOJI_00495 6.6e-20
PGHLFOJI_00496 4.5e-160
PGHLFOJI_00497 8.4e-75 K Transcriptional regulator
PGHLFOJI_00498 4.1e-186 D Alpha beta
PGHLFOJI_00499 1.6e-73 O OsmC-like protein
PGHLFOJI_00500 4e-192 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
PGHLFOJI_00501 0.0 yjcE P Sodium proton antiporter
PGHLFOJI_00502 1.2e-16 yvlA
PGHLFOJI_00503 2.2e-114 P Cobalt transport protein
PGHLFOJI_00504 8.3e-257 cbiO1 S ABC transporter, ATP-binding protein
PGHLFOJI_00505 2.7e-100 S ABC-type cobalt transport system, permease component
PGHLFOJI_00506 2e-180 iunH2 3.2.2.1 F nucleoside hydrolase
PGHLFOJI_00507 1.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
PGHLFOJI_00508 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PGHLFOJI_00509 3.3e-33 copZ P Heavy-metal-associated domain
PGHLFOJI_00510 1.2e-100 dps P Belongs to the Dps family
PGHLFOJI_00511 5.7e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PGHLFOJI_00512 2e-85
PGHLFOJI_00513 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PGHLFOJI_00514 2.5e-126 pgm3 G phosphoglycerate mutase family
PGHLFOJI_00515 1e-151 qorB 1.6.5.2 GM NmrA-like family
PGHLFOJI_00516 2.6e-231 pbuX F xanthine permease
PGHLFOJI_00517 9.7e-169 corA P CorA-like Mg2+ transporter protein
PGHLFOJI_00518 5.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PGHLFOJI_00519 2.3e-142 terC P membrane
PGHLFOJI_00520 2.3e-56 trxA1 O Belongs to the thioredoxin family
PGHLFOJI_00521 3.8e-226 L transposase, IS605 OrfB family
PGHLFOJI_00522 2.8e-44 L Transposase IS200 like
PGHLFOJI_00523 1.3e-307 recN L May be involved in recombinational repair of damaged DNA
PGHLFOJI_00524 6.2e-76 argR K Regulates arginine biosynthesis genes
PGHLFOJI_00525 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PGHLFOJI_00526 9.6e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PGHLFOJI_00527 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGHLFOJI_00528 6.1e-258 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGHLFOJI_00529 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PGHLFOJI_00530 4e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PGHLFOJI_00531 4.1e-72 yqhY S Asp23 family, cell envelope-related function
PGHLFOJI_00532 4e-206 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PGHLFOJI_00533 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PGHLFOJI_00534 9e-53 ysxB J Cysteine protease Prp
PGHLFOJI_00535 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
PGHLFOJI_00536 2.8e-114 K Transcriptional regulator
PGHLFOJI_00538 6.6e-93 dut S Protein conserved in bacteria
PGHLFOJI_00539 2.5e-175
PGHLFOJI_00540 1.6e-147
PGHLFOJI_00541 4.7e-13
PGHLFOJI_00542 4.2e-261 glnA 6.3.1.2 E glutamine synthetase
PGHLFOJI_00543 8.5e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PGHLFOJI_00544 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
PGHLFOJI_00545 1.5e-71 yqhL P Rhodanese-like protein
PGHLFOJI_00546 7.5e-180 glk 2.7.1.2 G Glucokinase
PGHLFOJI_00547 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
PGHLFOJI_00548 1.1e-116 gluP 3.4.21.105 S Peptidase, S54 family
PGHLFOJI_00549 2.4e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PGHLFOJI_00550 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PGHLFOJI_00551 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PGHLFOJI_00552 0.0 S membrane
PGHLFOJI_00553 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PGHLFOJI_00554 3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
PGHLFOJI_00555 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGHLFOJI_00556 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PGHLFOJI_00557 7.8e-60 yodB K Transcriptional regulator, HxlR family
PGHLFOJI_00558 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PGHLFOJI_00559 1.2e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGHLFOJI_00560 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PGHLFOJI_00561 8.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGHLFOJI_00562 9.6e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PGHLFOJI_00563 2.3e-232 V MatE
PGHLFOJI_00564 1.3e-279 arlS 2.7.13.3 T Histidine kinase
PGHLFOJI_00565 1.3e-120 K response regulator
PGHLFOJI_00566 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PGHLFOJI_00567 5e-96 yceD S Uncharacterized ACR, COG1399
PGHLFOJI_00568 1.7e-215 ylbM S Belongs to the UPF0348 family
PGHLFOJI_00569 2.3e-139 yqeM Q Methyltransferase
PGHLFOJI_00570 6.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PGHLFOJI_00571 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PGHLFOJI_00572 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PGHLFOJI_00573 2.6e-49 yhbY J RNA-binding protein
PGHLFOJI_00574 5.8e-216 yqeH S Ribosome biogenesis GTPase YqeH
PGHLFOJI_00575 2.2e-96 yqeG S HAD phosphatase, family IIIA
PGHLFOJI_00576 2.8e-23 yoaK S Protein of unknown function (DUF1275)
PGHLFOJI_00577 5.5e-19 yoaK S Protein of unknown function (DUF1275)
PGHLFOJI_00578 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PGHLFOJI_00579 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PGHLFOJI_00580 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PGHLFOJI_00581 1.6e-171 dnaI L Primosomal protein DnaI
PGHLFOJI_00582 4.8e-249 dnaB L replication initiation and membrane attachment
PGHLFOJI_00583 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PGHLFOJI_00584 7.9e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGHLFOJI_00585 2.1e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PGHLFOJI_00586 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGHLFOJI_00587 8.5e-139 aroD S Serine hydrolase (FSH1)
PGHLFOJI_00588 1.8e-114 ybhL S Belongs to the BI1 family
PGHLFOJI_00589 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PGHLFOJI_00590 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGHLFOJI_00591 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PGHLFOJI_00592 3.3e-58 ytzB S Small secreted protein
PGHLFOJI_00593 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PGHLFOJI_00594 1.7e-210 ecsB U ABC transporter
PGHLFOJI_00595 2.3e-133 ecsA V ABC transporter, ATP-binding protein
PGHLFOJI_00596 1.4e-77 hit FG histidine triad
PGHLFOJI_00598 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PGHLFOJI_00599 5.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
PGHLFOJI_00600 9.8e-56 yheA S Belongs to the UPF0342 family
PGHLFOJI_00601 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PGHLFOJI_00602 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PGHLFOJI_00604 1.7e-36
PGHLFOJI_00606 2e-200 folP 2.5.1.15 H dihydropteroate synthase
PGHLFOJI_00607 3.4e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
PGHLFOJI_00608 1.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PGHLFOJI_00609 3.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
PGHLFOJI_00610 8.4e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PGHLFOJI_00611 2.5e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PGHLFOJI_00612 2e-118 S CAAX protease self-immunity
PGHLFOJI_00613 2.9e-182 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
PGHLFOJI_00614 3.6e-111
PGHLFOJI_00615 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
PGHLFOJI_00616 3.9e-164 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PGHLFOJI_00617 1.2e-255 S Putative peptidoglycan binding domain
PGHLFOJI_00618 1.6e-57 S Domain of unknown function (DUF956)
PGHLFOJI_00619 3e-170 manN G system, mannose fructose sorbose family IID component
PGHLFOJI_00620 2.7e-122 manY G PTS system
PGHLFOJI_00621 5.3e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PGHLFOJI_00622 2.3e-181 yfeX P Peroxidase
PGHLFOJI_00623 6.5e-90 racA K Domain of unknown function (DUF1836)
PGHLFOJI_00624 6.6e-148 yitS S EDD domain protein, DegV family
PGHLFOJI_00625 3e-116 manA 5.3.1.8 G mannose-6-phosphate isomerase
PGHLFOJI_00626 9.6e-169 K LysR substrate binding domain
PGHLFOJI_00627 2.1e-159 MA20_14895 S Conserved hypothetical protein 698
PGHLFOJI_00628 2.9e-68 lytE M Lysin motif
PGHLFOJI_00629 3.4e-149 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
PGHLFOJI_00630 6.4e-204 oatA I Acyltransferase
PGHLFOJI_00631 3.3e-52
PGHLFOJI_00632 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PGHLFOJI_00633 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PGHLFOJI_00634 9.1e-116 ybbR S YbbR-like protein
PGHLFOJI_00635 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PGHLFOJI_00636 5.7e-166 murB 1.3.1.98 M Cell wall formation
PGHLFOJI_00637 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
PGHLFOJI_00638 1.6e-88 K Acetyltransferase (GNAT) domain
PGHLFOJI_00639 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PGHLFOJI_00640 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PGHLFOJI_00641 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PGHLFOJI_00642 5.5e-109 yxjI
PGHLFOJI_00643 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PGHLFOJI_00644 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PGHLFOJI_00645 4.5e-33 secG U Preprotein translocase
PGHLFOJI_00646 1.4e-289 clcA P chloride
PGHLFOJI_00647 4.3e-253 yifK E Amino acid permease
PGHLFOJI_00648 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PGHLFOJI_00649 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PGHLFOJI_00650 9.6e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PGHLFOJI_00651 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PGHLFOJI_00652 1e-15
PGHLFOJI_00653 7.7e-78 K Transcriptional regulator
PGHLFOJI_00654 1.7e-24 K DNA-binding helix-turn-helix protein
PGHLFOJI_00655 2.2e-35 S Protein of unknown function (DUF4256)
PGHLFOJI_00656 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PGHLFOJI_00657 7.8e-224 L transposase, IS605 OrfB family
PGHLFOJI_00658 3.3e-15
PGHLFOJI_00659 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PGHLFOJI_00660 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PGHLFOJI_00661 2.7e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PGHLFOJI_00662 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PGHLFOJI_00663 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PGHLFOJI_00664 2e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PGHLFOJI_00665 2.2e-131 stp 3.1.3.16 T phosphatase
PGHLFOJI_00666 0.0 KLT serine threonine protein kinase
PGHLFOJI_00667 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PGHLFOJI_00668 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PGHLFOJI_00669 1.2e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
PGHLFOJI_00670 7.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PGHLFOJI_00671 3.6e-58 asp S Asp23 family, cell envelope-related function
PGHLFOJI_00672 2.2e-291 yloV S DAK2 domain fusion protein YloV
PGHLFOJI_00673 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PGHLFOJI_00674 4.8e-164 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PGHLFOJI_00675 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGHLFOJI_00676 2e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PGHLFOJI_00677 0.0 smc D Required for chromosome condensation and partitioning
PGHLFOJI_00678 4.8e-197 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PGHLFOJI_00679 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PGHLFOJI_00680 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PGHLFOJI_00683 5.3e-62
PGHLFOJI_00684 6.1e-57 tlpA2 L Transposase IS200 like
PGHLFOJI_00685 1.1e-275 lacS G Transporter
PGHLFOJI_00686 0.0 rafA 3.2.1.22 G alpha-galactosidase
PGHLFOJI_00687 4.6e-180 galR K Transcriptional regulator
PGHLFOJI_00688 2e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PGHLFOJI_00689 2.1e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PGHLFOJI_00690 7.7e-185 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
PGHLFOJI_00691 1.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
PGHLFOJI_00692 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
PGHLFOJI_00693 2e-35
PGHLFOJI_00694 6.6e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PGHLFOJI_00695 5.3e-119 tcyB U Binding-protein-dependent transport system inner membrane component
PGHLFOJI_00696 5.7e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PGHLFOJI_00697 2e-52
PGHLFOJI_00698 4e-170 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGHLFOJI_00699 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PGHLFOJI_00700 6.9e-147 pnuC H nicotinamide mononucleotide transporter
PGHLFOJI_00701 1.1e-92 ymdB S Macro domain protein
PGHLFOJI_00702 0.0 pepO 3.4.24.71 O Peptidase family M13
PGHLFOJI_00703 1.8e-229 pbuG S permease
PGHLFOJI_00704 2.1e-45
PGHLFOJI_00705 4.9e-213 S Putative metallopeptidase domain
PGHLFOJI_00706 8e-205 3.1.3.1 S associated with various cellular activities
PGHLFOJI_00707 1.3e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PGHLFOJI_00708 6.8e-65 yeaO S Protein of unknown function, DUF488
PGHLFOJI_00710 4.8e-125 yrkL S Flavodoxin-like fold
PGHLFOJI_00711 1.5e-55
PGHLFOJI_00712 1.7e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
PGHLFOJI_00713 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PGHLFOJI_00714 7e-102
PGHLFOJI_00715 9.5e-26
PGHLFOJI_00716 6.3e-171 scrR K Transcriptional regulator, LacI family
PGHLFOJI_00717 1.2e-147 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PGHLFOJI_00718 2.6e-46 czrA K Transcriptional regulator, ArsR family
PGHLFOJI_00719 6.2e-68 XK27_08315 M Sulfatase
PGHLFOJI_00720 5e-167 map 3.4.11.18 E Methionine Aminopeptidase
PGHLFOJI_00721 8.5e-78 fld C Flavodoxin
PGHLFOJI_00722 3.6e-73 gtcA S Teichoic acid glycosylation protein
PGHLFOJI_00724 5.6e-234 yfmL 3.6.4.13 L DEAD DEAH box helicase
PGHLFOJI_00725 6.4e-190 mocA S Oxidoreductase
PGHLFOJI_00726 4.9e-63 S Domain of unknown function (DUF4828)
PGHLFOJI_00727 1.4e-104 yvdD 3.2.2.10 S Belongs to the LOG family
PGHLFOJI_00728 1.9e-161 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PGHLFOJI_00729 3.1e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PGHLFOJI_00730 4.7e-140 S NADPH-dependent FMN reductase
PGHLFOJI_00731 2.3e-33 yneR S Belongs to the HesB IscA family
PGHLFOJI_00732 2.7e-216 L transposase, IS605 OrfB family
PGHLFOJI_00733 8.2e-304 ybiT S ABC transporter, ATP-binding protein
PGHLFOJI_00734 2e-85 dps P Belongs to the Dps family
PGHLFOJI_00735 1.6e-105
PGHLFOJI_00736 1.3e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PGHLFOJI_00737 1.4e-101 K helix_turn_helix multiple antibiotic resistance protein
PGHLFOJI_00738 5.5e-131 fsr EGP Major Facilitator Superfamily
PGHLFOJI_00739 5.4e-100 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PGHLFOJI_00740 2.3e-102 S CAAX protease self-immunity
PGHLFOJI_00742 6.3e-120 Q Methyltransferase domain
PGHLFOJI_00743 2.5e-90 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PGHLFOJI_00744 2.8e-51 K 2 iron, 2 sulfur cluster binding
PGHLFOJI_00745 0.0 mco Q Multicopper oxidase
PGHLFOJI_00746 7.6e-169 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGHLFOJI_00747 4.1e-89 S Aminoacyl-tRNA editing domain
PGHLFOJI_00748 3.1e-75 ddaH 3.5.3.18 E Amidinotransferase
PGHLFOJI_00750 2e-194 nhaC C Na H antiporter NhaC
PGHLFOJI_00751 1.4e-185 S Phosphotransferase system, EIIC
PGHLFOJI_00752 1.8e-22 D mRNA cleavage
PGHLFOJI_00753 1.9e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PGHLFOJI_00754 4.7e-123 srtA 3.4.22.70 M sortase family
PGHLFOJI_00755 3.3e-29 mdtG EGP Major facilitator Superfamily
PGHLFOJI_00756 6e-41 rpmE2 J Ribosomal protein L31
PGHLFOJI_00757 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGHLFOJI_00758 1.1e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PGHLFOJI_00759 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PGHLFOJI_00760 3.2e-74 ywiB S Domain of unknown function (DUF1934)
PGHLFOJI_00761 5.7e-266 ywfO S HD domain protein
PGHLFOJI_00762 4.8e-143 yxeH S hydrolase
PGHLFOJI_00763 3e-32
PGHLFOJI_00764 3.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PGHLFOJI_00765 7.3e-205 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PGHLFOJI_00766 6.4e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PGHLFOJI_00767 3.2e-128 znuB U ABC 3 transport family
PGHLFOJI_00768 5.4e-95 fhuC P ABC transporter
PGHLFOJI_00769 2.2e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
PGHLFOJI_00770 1.3e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PGHLFOJI_00771 1.4e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PGHLFOJI_00772 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PGHLFOJI_00773 1.8e-147 tatD L hydrolase, TatD family
PGHLFOJI_00774 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGHLFOJI_00775 6.2e-162 yunF F Protein of unknown function DUF72
PGHLFOJI_00776 1.2e-211 norA EGP Major facilitator Superfamily
PGHLFOJI_00777 4.8e-128 cobB K SIR2 family
PGHLFOJI_00778 2.2e-187
PGHLFOJI_00779 4e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PGHLFOJI_00780 6.6e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PGHLFOJI_00781 0.0 helD 3.6.4.12 L DNA helicase
PGHLFOJI_00782 4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PGHLFOJI_00783 9.6e-155 metQ_4 P Belongs to the nlpA lipoprotein family
PGHLFOJI_00784 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PGHLFOJI_00785 1.1e-205 yfnA E Amino Acid
PGHLFOJI_00786 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
PGHLFOJI_00787 1.7e-105 gmk2 2.7.4.8 F Guanylate kinase
PGHLFOJI_00788 6.8e-83 zur P Belongs to the Fur family
PGHLFOJI_00790 6.3e-168
PGHLFOJI_00791 5.3e-187 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PGHLFOJI_00792 1.9e-92 K Transcriptional regulator (TetR family)
PGHLFOJI_00793 5.3e-207 V domain protein
PGHLFOJI_00794 4.8e-77
PGHLFOJI_00796 3.3e-186 ydaM M Glycosyl transferase family group 2
PGHLFOJI_00797 9.3e-09 G Glycosyl hydrolases family 8
PGHLFOJI_00798 1.3e-101 G Glycosyl hydrolases family 8
PGHLFOJI_00799 1.6e-141 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
PGHLFOJI_00800 8.7e-107 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGHLFOJI_00801 2.5e-297 ybeC E amino acid
PGHLFOJI_00802 3.6e-134 pnuC H nicotinamide mononucleotide transporter
PGHLFOJI_00803 3e-209 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PGHLFOJI_00804 3.3e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PGHLFOJI_00805 9e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PGHLFOJI_00806 8.6e-119 dedA S SNARE associated Golgi protein
PGHLFOJI_00807 0.0 helD 3.6.4.12 L DNA helicase
PGHLFOJI_00808 2.5e-161 EG EamA-like transporter family
PGHLFOJI_00809 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PGHLFOJI_00810 1.7e-134 IQ Dehydrogenase reductase
PGHLFOJI_00811 3.2e-21
PGHLFOJI_00812 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PGHLFOJI_00813 2.4e-70 L nuclease
PGHLFOJI_00814 8.4e-162 F DNA/RNA non-specific endonuclease
PGHLFOJI_00815 3.3e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PGHLFOJI_00816 3.1e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PGHLFOJI_00817 7.5e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PGHLFOJI_00818 0.0 asnB 6.3.5.4 E Asparagine synthase
PGHLFOJI_00819 6.6e-220 lysP E amino acid
PGHLFOJI_00820 7e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PGHLFOJI_00821 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PGHLFOJI_00822 1.1e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PGHLFOJI_00823 4.8e-154 jag S R3H domain protein
PGHLFOJI_00824 3.4e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGHLFOJI_00825 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PGHLFOJI_00826 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PGHLFOJI_00827 1.4e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PGHLFOJI_00828 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PGHLFOJI_00829 2.2e-34 yaaA S S4 domain protein YaaA
PGHLFOJI_00830 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PGHLFOJI_00831 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGHLFOJI_00832 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGHLFOJI_00833 2.7e-61
PGHLFOJI_00834 1.9e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PGHLFOJI_00835 5.6e-61 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PGHLFOJI_00836 0.0 dnaK O Heat shock 70 kDa protein
PGHLFOJI_00837 1.1e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PGHLFOJI_00838 2.8e-54 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PGHLFOJI_00839 1.6e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PGHLFOJI_00840 1.4e-36 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PGHLFOJI_00841 2.2e-41 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PGHLFOJI_00842 4.2e-55 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PGHLFOJI_00843 2.9e-51 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PGHLFOJI_00844 1.9e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PGHLFOJI_00845 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PGHLFOJI_00846 3.3e-09
PGHLFOJI_00847 1.9e-112 3.1.3.73 G phosphoglycerate mutase
PGHLFOJI_00848 3.2e-112 C aldo keto reductase
PGHLFOJI_00849 8.3e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PGHLFOJI_00850 9.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGHLFOJI_00851 2.7e-268 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
PGHLFOJI_00852 7.9e-79 K 2 iron, 2 sulfur cluster binding
PGHLFOJI_00853 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PGHLFOJI_00854 9.2e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PGHLFOJI_00855 9.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
PGHLFOJI_00856 3.4e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PGHLFOJI_00857 7.2e-54 C FMN binding
PGHLFOJI_00858 1.7e-28 T His Kinase A (phosphoacceptor) domain
PGHLFOJI_00859 7.8e-52 T Transcriptional regulatory protein, C terminal
PGHLFOJI_00860 1.2e-15 S ABC-type transport system involved in multi-copper enzyme maturation permease component
PGHLFOJI_00861 3.7e-221 iscS 2.8.1.7 E Aminotransferase class V
PGHLFOJI_00863 5.9e-100 G Protein of unknown function (DUF4038)
PGHLFOJI_00864 3.7e-184 C Oxidoreductase
PGHLFOJI_00865 1.2e-89 deoR K sugar-binding domain protein
PGHLFOJI_00866 4.8e-115 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
PGHLFOJI_00867 1.3e-149 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
PGHLFOJI_00868 1.6e-195 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PGHLFOJI_00869 7.2e-89 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PGHLFOJI_00870 5.3e-08 L PFAM Integrase catalytic
PGHLFOJI_00871 7.7e-46 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PGHLFOJI_00872 5.3e-167 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PGHLFOJI_00873 2.4e-83 csm5 L RAMP superfamily
PGHLFOJI_00874 7.9e-78 csm4 L CRISPR-associated RAMP protein, Csm4 family
PGHLFOJI_00875 5.9e-83 csm3 L RAMP superfamily
PGHLFOJI_00876 1.3e-24 csm2 L Csm2 Type III-A
PGHLFOJI_00877 1.2e-226 csm1 S CRISPR-associated protein Csm1 family
PGHLFOJI_00878 4e-51 cas6 S Pfam:DUF2276
PGHLFOJI_00879 0.0 N Uncharacterized conserved protein (DUF2075)
PGHLFOJI_00881 2e-100 K DNA-templated transcription, initiation
PGHLFOJI_00882 5.2e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGHLFOJI_00883 3.4e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGHLFOJI_00884 1.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PGHLFOJI_00885 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
PGHLFOJI_00886 0.0 ubiB S ABC1 family
PGHLFOJI_00887 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
PGHLFOJI_00888 2.8e-11 ywkB S Membrane transport protein
PGHLFOJI_00889 8.8e-53 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
PGHLFOJI_00890 1.6e-140 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
PGHLFOJI_00891 4.8e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PGHLFOJI_00892 2.6e-80 hmpT S ECF-type riboflavin transporter, S component
PGHLFOJI_00893 5.1e-167 1.1.1.346 C Aldo keto reductase
PGHLFOJI_00894 7.5e-161 S DUF218 domain
PGHLFOJI_00897 6.3e-96 K Acetyltransferase (GNAT) domain
PGHLFOJI_00898 1.3e-164 I alpha/beta hydrolase fold
PGHLFOJI_00899 4.7e-120 S Phage minor capsid protein 2
PGHLFOJI_00902 3.4e-216 2.6.1.1 E Aminotransferase
PGHLFOJI_00903 4.3e-184 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
PGHLFOJI_00904 1.3e-64 EGP Sugar (and other) transporter
PGHLFOJI_00905 3.6e-53 EGP Sugar (and other) transporter
PGHLFOJI_00906 1.9e-93 EGP Sugar (and other) transporter
PGHLFOJI_00907 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
PGHLFOJI_00908 1.3e-85 S Fic/DOC family
PGHLFOJI_00909 8.1e-77 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PGHLFOJI_00910 4.3e-107 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PGHLFOJI_00911 1.7e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PGHLFOJI_00912 1.7e-260 arcD E Amino acid permease
PGHLFOJI_00913 8.5e-118 5.1.1.13 M racemase activity, acting on amino acids and derivatives
PGHLFOJI_00914 9.5e-36 odh 1.5.1.28 C NAD NADP octopine nopaline dehydrogenase
PGHLFOJI_00915 6.5e-109 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
PGHLFOJI_00916 1.7e-29 clcA P chloride
PGHLFOJI_00917 8.7e-67 clcA P chloride
PGHLFOJI_00918 6.5e-18 lmrB EGP Major facilitator Superfamily
PGHLFOJI_00920 1.9e-20 L Helix-turn-helix domain
PGHLFOJI_00921 1.2e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PGHLFOJI_00922 6e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PGHLFOJI_00923 1.7e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PGHLFOJI_00924 1.5e-76 yphH S Cupin domain
PGHLFOJI_00925 7.6e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PGHLFOJI_00926 2.9e-226 mtnE 2.6.1.83 E Aminotransferase
PGHLFOJI_00927 2.3e-147 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PGHLFOJI_00928 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PGHLFOJI_00929 2.6e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PGHLFOJI_00930 1.6e-162 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PGHLFOJI_00931 1e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PGHLFOJI_00932 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PGHLFOJI_00933 4.1e-53 KT PspC domain protein
PGHLFOJI_00934 4.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PGHLFOJI_00935 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PGHLFOJI_00936 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PGHLFOJI_00937 1.4e-127 comFC S Competence protein
PGHLFOJI_00938 2.6e-183 comFA L Helicase C-terminal domain protein
PGHLFOJI_00939 4.7e-11 comFA L Helicase C-terminal domain protein
PGHLFOJI_00940 9e-113 yvyE 3.4.13.9 S YigZ family
PGHLFOJI_00941 1.9e-37
PGHLFOJI_00942 0.0 ydaO E amino acid
PGHLFOJI_00943 1e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PGHLFOJI_00944 7.4e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PGHLFOJI_00945 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PGHLFOJI_00946 0.0 uup S ABC transporter, ATP-binding protein
PGHLFOJI_00947 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PGHLFOJI_00948 9.7e-92 bioY S BioY family
PGHLFOJI_00949 5.8e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PGHLFOJI_00950 3.3e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PGHLFOJI_00951 1.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PGHLFOJI_00952 4.6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PGHLFOJI_00953 5e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PGHLFOJI_00954 4.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PGHLFOJI_00955 1.3e-229 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PGHLFOJI_00956 2.7e-129 IQ reductase
PGHLFOJI_00957 2.8e-171 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PGHLFOJI_00958 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGHLFOJI_00959 1.7e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGHLFOJI_00960 8.7e-75 marR K Transcriptional regulator, MarR family
PGHLFOJI_00961 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PGHLFOJI_00963 1.2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PGHLFOJI_00964 7.4e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PGHLFOJI_00965 2.2e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PGHLFOJI_00966 7.6e-216 arcT 2.6.1.1 E Aminotransferase
PGHLFOJI_00967 3.5e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
PGHLFOJI_00968 1.1e-259 E Arginine ornithine antiporter
PGHLFOJI_00969 4.1e-200 arcA 3.5.3.6 E Arginine
PGHLFOJI_00970 5e-23 arcA 3.5.3.6 E Arginine
PGHLFOJI_00971 1.4e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
PGHLFOJI_00972 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PGHLFOJI_00973 1.8e-148 KT YcbB domain
PGHLFOJI_00974 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PGHLFOJI_00975 2.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PGHLFOJI_00976 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PGHLFOJI_00977 1.1e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PGHLFOJI_00978 1.2e-145 fat 3.1.2.21 I Acyl-ACP thioesterase
PGHLFOJI_00979 1.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PGHLFOJI_00980 7.6e-55 yabA L Involved in initiation control of chromosome replication
PGHLFOJI_00981 4.9e-193 holB 2.7.7.7 L DNA polymerase III
PGHLFOJI_00982 1.2e-52 yaaQ S Cyclic-di-AMP receptor
PGHLFOJI_00983 6e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PGHLFOJI_00984 2.4e-21 S Protein of unknown function (DUF2508)
PGHLFOJI_00985 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PGHLFOJI_00986 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PGHLFOJI_00987 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGHLFOJI_00989 6.3e-80 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PGHLFOJI_00990 2e-35 nrdH O Glutaredoxin
PGHLFOJI_00991 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGHLFOJI_00992 3.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGHLFOJI_00993 6e-247 brnQ U Component of the transport system for branched-chain amino acids
PGHLFOJI_00994 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PGHLFOJI_00995 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PGHLFOJI_00996 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PGHLFOJI_00997 7.7e-175 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PGHLFOJI_00998 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
PGHLFOJI_00999 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PGHLFOJI_01000 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PGHLFOJI_01001 1.7e-243 steT E amino acid
PGHLFOJI_01002 1.3e-151 2.1.1.37 H C-5 cytosine-specific DNA methylase
PGHLFOJI_01003 6.2e-118 L AlwI restriction endonuclease
PGHLFOJI_01004 5.5e-95 K transcriptional regulator
PGHLFOJI_01005 2.4e-254 lmrB EGP Major facilitator Superfamily
PGHLFOJI_01006 1.1e-07 S Domain of unknown function (DUF4811)
PGHLFOJI_01010 3.5e-38 S Cytochrome B5
PGHLFOJI_01011 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PGHLFOJI_01012 4.9e-215 2.1.1.14 E methionine synthase, vitamin-B12 independent
PGHLFOJI_01013 1e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
PGHLFOJI_01014 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
PGHLFOJI_01015 2.5e-66 wecD K Acetyltransferase (GNAT) family
PGHLFOJI_01016 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
PGHLFOJI_01017 5.9e-82 S Psort location Cytoplasmic, score
PGHLFOJI_01018 2.3e-72 K helix_turn_helix, mercury resistance
PGHLFOJI_01019 1.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
PGHLFOJI_01020 1.7e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
PGHLFOJI_01021 3.2e-58 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PGHLFOJI_01022 2.2e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PGHLFOJI_01023 2.3e-136 ycsF S LamB/YcsF family
PGHLFOJI_01024 2.7e-211 ycsG P Natural resistance-associated macrophage protein
PGHLFOJI_01025 1.6e-208 EGP Major facilitator Superfamily
PGHLFOJI_01026 1.2e-138 IQ reductase
PGHLFOJI_01027 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
PGHLFOJI_01028 3.2e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PGHLFOJI_01029 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PGHLFOJI_01030 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PGHLFOJI_01031 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PGHLFOJI_01032 3.2e-166 camS S sex pheromone
PGHLFOJI_01033 1e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGHLFOJI_01034 8.8e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PGHLFOJI_01035 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGHLFOJI_01036 5.7e-186 yegS 2.7.1.107 G Lipid kinase
PGHLFOJI_01037 3.2e-264 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGHLFOJI_01038 0.0 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PGHLFOJI_01039 6.3e-16 2.1.1.303 K DNA-binding transcription factor activity
PGHLFOJI_01040 1.8e-292 L Recombinase
PGHLFOJI_01041 1.2e-191 L Recombinase zinc beta ribbon domain
PGHLFOJI_01042 9e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PGHLFOJI_01043 8.7e-88 lemA S LemA family
PGHLFOJI_01044 4.9e-157 htpX O Belongs to the peptidase M48B family
PGHLFOJI_01045 1.4e-259 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PGHLFOJI_01046 5.4e-254 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PGHLFOJI_01047 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PGHLFOJI_01048 9.6e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PGHLFOJI_01049 5e-57 L Toxic component of a toxin-antitoxin (TA) module
PGHLFOJI_01050 8.1e-114 S (CBS) domain
PGHLFOJI_01051 1.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PGHLFOJI_01052 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PGHLFOJI_01053 1.6e-39 yabO J S4 domain protein
PGHLFOJI_01054 1.5e-56 divIC D Septum formation initiator
PGHLFOJI_01055 3e-87 yabR J RNA binding
PGHLFOJI_01056 1.2e-255 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PGHLFOJI_01057 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PGHLFOJI_01058 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PGHLFOJI_01059 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PGHLFOJI_01060 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGHLFOJI_01061 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PGHLFOJI_01062 4.9e-159 xth 3.1.11.2 L exodeoxyribonuclease III
PGHLFOJI_01063 6.7e-56
PGHLFOJI_01064 4.5e-16 M domain protein
PGHLFOJI_01065 1.1e-234 kgtP EGP Sugar (and other) transporter
PGHLFOJI_01066 4.2e-141 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
PGHLFOJI_01067 7.5e-153 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHLFOJI_01068 2.8e-149 isdE P Periplasmic binding protein
PGHLFOJI_01069 1e-94 M Iron Transport-associated domain
PGHLFOJI_01070 6.3e-276 isdH M Iron Transport-associated domain
PGHLFOJI_01073 6.5e-54 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PGHLFOJI_01074 3.8e-91 P Cadmium resistance transporter
PGHLFOJI_01075 5.6e-30 C Aldo/keto reductase family
PGHLFOJI_01078 1e-84 C Aldo keto reductase
PGHLFOJI_01079 9.6e-81 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHLFOJI_01081 3.2e-83 S Alpha/beta hydrolase family
PGHLFOJI_01082 7.8e-120 pnb C nitroreductase
PGHLFOJI_01083 5.6e-23 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PGHLFOJI_01084 1.7e-42 S Tautomerase enzyme
PGHLFOJI_01085 3.6e-29 S Domain of unknown function (DUF4767)
PGHLFOJI_01086 5.7e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PGHLFOJI_01087 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PGHLFOJI_01088 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
PGHLFOJI_01089 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PGHLFOJI_01090 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PGHLFOJI_01091 1.1e-104 sigH K Belongs to the sigma-70 factor family
PGHLFOJI_01092 5.2e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGHLFOJI_01093 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PGHLFOJI_01094 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PGHLFOJI_01095 7.8e-100 ywlG S Belongs to the UPF0340 family
PGHLFOJI_01096 1.8e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PGHLFOJI_01097 2.3e-204 yacL S domain protein
PGHLFOJI_01098 5.6e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PGHLFOJI_01099 1.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PGHLFOJI_01100 4.2e-55 HA62_12640 S GCN5-related N-acetyl-transferase
PGHLFOJI_01101 1.3e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PGHLFOJI_01102 1.1e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
PGHLFOJI_01103 6.8e-264 pepC 3.4.22.40 E Peptidase C1-like family
PGHLFOJI_01104 1.3e-167 I alpha/beta hydrolase fold
PGHLFOJI_01105 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PGHLFOJI_01106 2.3e-168 mleP2 S Sodium Bile acid symporter family
PGHLFOJI_01107 8.8e-189 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
PGHLFOJI_01108 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PGHLFOJI_01109 8.4e-229 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PGHLFOJI_01110 3.1e-10 K transcriptional regulator
PGHLFOJI_01111 3.7e-164 K AI-2E family transporter
PGHLFOJI_01112 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PGHLFOJI_01113 4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PGHLFOJI_01114 5.9e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PGHLFOJI_01115 3.3e-255 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PGHLFOJI_01116 2.1e-172 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
PGHLFOJI_01117 7e-236 S response to antibiotic
PGHLFOJI_01118 6.5e-136 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PGHLFOJI_01119 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGHLFOJI_01120 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGHLFOJI_01121 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGHLFOJI_01122 1.1e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PGHLFOJI_01123 5.1e-107 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PGHLFOJI_01124 2.1e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PGHLFOJI_01125 2.5e-86 brnQ U Component of the transport system for branched-chain amino acids
PGHLFOJI_01126 4.4e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGHLFOJI_01127 2.8e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PGHLFOJI_01128 5.8e-97 metI P ABC transporter permease
PGHLFOJI_01129 6.1e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PGHLFOJI_01130 2.7e-149 metQ1 P Belongs to the nlpA lipoprotein family
PGHLFOJI_01131 6e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
PGHLFOJI_01132 3.2e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
PGHLFOJI_01133 6.9e-47
PGHLFOJI_01134 1.8e-21 gntT EG gluconate transmembrane transporter activity
PGHLFOJI_01135 1.1e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PGHLFOJI_01136 1.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PGHLFOJI_01137 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PGHLFOJI_01138 3.7e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PGHLFOJI_01139 6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PGHLFOJI_01140 7.4e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PGHLFOJI_01141 3.8e-38 K transcriptional regulator
PGHLFOJI_01142 1.3e-100 P Cadmium resistance transporter
PGHLFOJI_01143 3.2e-116 S Protein of unknown function (DUF554)
PGHLFOJI_01144 7.1e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGHLFOJI_01145 3.5e-157 P Belongs to the nlpA lipoprotein family
PGHLFOJI_01146 3.9e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGHLFOJI_01147 2.5e-37 V CAAX protease self-immunity
PGHLFOJI_01148 2.3e-67 psiE S Phosphate-starvation-inducible E
PGHLFOJI_01149 4.4e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PGHLFOJI_01150 5.8e-112 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PGHLFOJI_01151 2.1e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PGHLFOJI_01152 1.8e-139 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PGHLFOJI_01153 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PGHLFOJI_01154 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PGHLFOJI_01155 8.6e-93 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PGHLFOJI_01156 8.4e-35 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PGHLFOJI_01157 1.3e-27 S CRISPR-associated protein (Cas_Csn2)
PGHLFOJI_01158 7.5e-197 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PGHLFOJI_01159 4.7e-299 ytgP S Polysaccharide biosynthesis protein
PGHLFOJI_01160 2.6e-42
PGHLFOJI_01161 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PGHLFOJI_01162 4.1e-127 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
PGHLFOJI_01163 9.9e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PGHLFOJI_01164 4.8e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PGHLFOJI_01165 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PGHLFOJI_01166 1e-51
PGHLFOJI_01167 1.2e-97 tag 3.2.2.20 L glycosylase
PGHLFOJI_01168 9.9e-253 EGP Major facilitator Superfamily
PGHLFOJI_01169 7.4e-85 perR P Belongs to the Fur family
PGHLFOJI_01170 7e-248 cycA E Amino acid permease
PGHLFOJI_01171 4e-22
PGHLFOJI_01174 2.3e-14 L Initiator Replication protein
PGHLFOJI_01179 9.7e-74 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
PGHLFOJI_01180 9e-12 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PGHLFOJI_01181 1.6e-171 mutR K Transcriptional activator, Rgg GadR MutR family
PGHLFOJI_01182 1.6e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
PGHLFOJI_01183 3.2e-229 gntT EG Gluconate
PGHLFOJI_01184 1.9e-181 K Transcriptional regulator, LacI family
PGHLFOJI_01185 6.1e-60 yneR
PGHLFOJI_01186 2.8e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PGHLFOJI_01187 2.2e-96 V VanZ like family
PGHLFOJI_01188 3.1e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PGHLFOJI_01189 2.4e-49 ywnB S NAD(P)H-binding
PGHLFOJI_01190 2.1e-65 yjcE P Sodium proton antiporter
PGHLFOJI_01191 5.9e-76
PGHLFOJI_01192 4.3e-183
PGHLFOJI_01193 6.4e-99 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PGHLFOJI_01194 1.1e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PGHLFOJI_01195 1e-179 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PGHLFOJI_01196 7.7e-263 lysC 2.7.2.4 E Belongs to the aspartokinase family
PGHLFOJI_01197 2.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PGHLFOJI_01198 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PGHLFOJI_01199 4.7e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PGHLFOJI_01200 9.2e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PGHLFOJI_01201 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PGHLFOJI_01202 1.7e-218 patA 2.6.1.1 E Aminotransferase
PGHLFOJI_01203 3.3e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PGHLFOJI_01204 3e-227 ktrB P Potassium uptake protein
PGHLFOJI_01205 7.5e-118 ktrA P domain protein
PGHLFOJI_01206 1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
PGHLFOJI_01207 2.9e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PGHLFOJI_01208 5.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PGHLFOJI_01210 0.0 dnaE 2.7.7.7 L DNA polymerase
PGHLFOJI_01211 9.1e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PGHLFOJI_01212 1.6e-168 cvfB S S1 domain
PGHLFOJI_01213 6.9e-132 xerD D recombinase XerD
PGHLFOJI_01214 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGHLFOJI_01215 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PGHLFOJI_01216 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PGHLFOJI_01217 2.8e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PGHLFOJI_01218 2.4e-80 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PGHLFOJI_01219 1.3e-198 ypbB 5.1.3.1 S Helix-turn-helix domain
PGHLFOJI_01220 9e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
PGHLFOJI_01221 9.7e-31 M Lysin motif
PGHLFOJI_01222 5.8e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PGHLFOJI_01223 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
PGHLFOJI_01224 1.7e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PGHLFOJI_01225 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PGHLFOJI_01226 1.2e-233 S Tetratricopeptide repeat protein
PGHLFOJI_01227 4.7e-165 xerD L Phage integrase, N-terminal SAM-like domain
PGHLFOJI_01228 7.6e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PGHLFOJI_01229 0.0 yfmR S ABC transporter, ATP-binding protein
PGHLFOJI_01230 2.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PGHLFOJI_01231 2.5e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PGHLFOJI_01232 1.2e-109 hlyIII S protein, hemolysin III
PGHLFOJI_01233 1.2e-152 DegV S EDD domain protein, DegV family
PGHLFOJI_01234 2.9e-218 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
PGHLFOJI_01235 3.2e-107 cat S Bacterial transferase hexapeptide (six repeats)
PGHLFOJI_01236 1.1e-167 ypmR E lipolytic protein G-D-S-L family
PGHLFOJI_01237 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PGHLFOJI_01238 3.1e-36 yozE S Belongs to the UPF0346 family
PGHLFOJI_01239 1.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PGHLFOJI_01240 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGHLFOJI_01241 8.1e-165 dprA LU DNA protecting protein DprA
PGHLFOJI_01242 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGHLFOJI_01243 7.3e-155 D DNA integration
PGHLFOJI_01244 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
PGHLFOJI_01245 2.8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PGHLFOJI_01246 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGHLFOJI_01247 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGHLFOJI_01248 5.2e-95 S Protein of unknown function (DUF1440)
PGHLFOJI_01249 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
PGHLFOJI_01250 2.3e-71 yqkB S Belongs to the HesB IscA family
PGHLFOJI_01251 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PGHLFOJI_01252 2e-76 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
PGHLFOJI_01253 1.3e-81 yebR 1.8.4.14 T GAF domain-containing protein
PGHLFOJI_01254 1.1e-242 U Belongs to the purine-cytosine permease (2.A.39) family
PGHLFOJI_01255 8e-243 codA 3.5.4.1 F cytosine deaminase
PGHLFOJI_01256 0.0 oppD EP Psort location Cytoplasmic, score
PGHLFOJI_01258 2e-255 rarA L recombination factor protein RarA
PGHLFOJI_01259 1.7e-117 S Protein of unknown function (DUF554)
PGHLFOJI_01260 9.3e-245 yhjX P Major Facilitator Superfamily
PGHLFOJI_01261 1.9e-46 L Transposase
PGHLFOJI_01262 7.9e-86 2.5.1.74 H UbiA prenyltransferase family
PGHLFOJI_01263 4.2e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGHLFOJI_01264 2.5e-253 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
PGHLFOJI_01265 2e-10 L Transposase
PGHLFOJI_01266 2.4e-127 L Transposase
PGHLFOJI_01267 9.9e-214 nupG F Nucleoside transporter
PGHLFOJI_01268 2.2e-144 rihC 3.2.2.1 F Nucleoside
PGHLFOJI_01269 3.1e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PGHLFOJI_01270 1.1e-156 noc K Belongs to the ParB family
PGHLFOJI_01271 1.9e-147 spo0J K Belongs to the ParB family
PGHLFOJI_01272 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
PGHLFOJI_01273 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PGHLFOJI_01274 1.9e-133 XK27_01040 S Protein of unknown function (DUF1129)
PGHLFOJI_01275 1.7e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PGHLFOJI_01276 4.2e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGHLFOJI_01277 3.5e-87 galR K Transcriptional regulator
PGHLFOJI_01278 3.5e-83 glcU U sugar transport
PGHLFOJI_01279 3e-74 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGHLFOJI_01281 2.4e-83 ydcK S Belongs to the SprT family
PGHLFOJI_01282 0.0 yhgF K Tex-like protein N-terminal domain protein
PGHLFOJI_01283 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PGHLFOJI_01284 2.6e-191 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGHLFOJI_01285 1e-81 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGHLFOJI_01286 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
PGHLFOJI_01287 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PGHLFOJI_01288 9.6e-115
PGHLFOJI_01291 7.1e-166 yjjH S Calcineurin-like phosphoesterase
PGHLFOJI_01292 3.7e-258 dtpT U amino acid peptide transporter
PGHLFOJI_01293 1.4e-168 D nuclear chromosome segregation
PGHLFOJI_01294 8.2e-96 L transposase, IS605 OrfB family
PGHLFOJI_01295 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
PGHLFOJI_01296 4.4e-169 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
PGHLFOJI_01297 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGHLFOJI_01298 1.4e-83 nrdI F NrdI Flavodoxin like
PGHLFOJI_01299 1.1e-109 M ErfK YbiS YcfS YnhG
PGHLFOJI_01300 5.8e-205 nrnB S DHHA1 domain
PGHLFOJI_01301 3.4e-291 S ABC transporter, ATP-binding protein
PGHLFOJI_01302 7e-181 ABC-SBP S ABC transporter
PGHLFOJI_01303 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PGHLFOJI_01304 1.2e-132 XK27_08845 S ABC transporter, ATP-binding protein
PGHLFOJI_01306 1.6e-224 amtB P ammonium transporter
PGHLFOJI_01307 9.5e-234 mepA V MATE efflux family protein
PGHLFOJI_01308 6.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PGHLFOJI_01309 1.3e-54 tlpA2 L Transposase IS200 like
PGHLFOJI_01310 2e-94 K Transcriptional regulator, TetR family
PGHLFOJI_01311 3.7e-78 hsp O Belongs to the small heat shock protein (HSP20) family
PGHLFOJI_01312 4.8e-85 ykhA 3.1.2.20 I Thioesterase superfamily
PGHLFOJI_01313 3.8e-63 lytE M LysM domain protein
PGHLFOJI_01314 6.7e-198 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
PGHLFOJI_01315 6e-236 F Permease
PGHLFOJI_01316 5.4e-161 sufD O Uncharacterized protein family (UPF0051)
PGHLFOJI_01317 1.1e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PGHLFOJI_01318 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PGHLFOJI_01319 2e-110 XK27_05795 P ABC transporter permease
PGHLFOJI_01320 9e-142 ET Bacterial periplasmic substrate-binding proteins
PGHLFOJI_01321 1.3e-11 qacC P COG2076 Membrane transporters of cations and cationic drugs
PGHLFOJI_01333 2e-230 ndh 1.6.99.3 C NADH dehydrogenase
PGHLFOJI_01334 5.9e-143 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
PGHLFOJI_01335 1.5e-170 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHLFOJI_01336 1.3e-57 S Flavodoxin
PGHLFOJI_01337 3.7e-72 moaE 2.8.1.12 H MoaE protein
PGHLFOJI_01338 6.4e-35 moaD 2.8.1.12 H ThiS family
PGHLFOJI_01339 1e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PGHLFOJI_01340 5.2e-215 narK P Major Facilitator Superfamily
PGHLFOJI_01341 1.5e-58 yitW S Iron-sulfur cluster assembly protein
PGHLFOJI_01342 4.5e-163 hipB K Helix-turn-helix
PGHLFOJI_01343 2.3e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PGHLFOJI_01345 5.7e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
PGHLFOJI_01346 3e-184
PGHLFOJI_01347 1.2e-39
PGHLFOJI_01348 4e-116 nreC K PFAM regulatory protein LuxR
PGHLFOJI_01349 1.5e-86 comP 2.7.13.3 F Sensor histidine kinase
PGHLFOJI_01350 4e-79 comP 2.7.13.3 F Sensor histidine kinase
PGHLFOJI_01351 4.3e-49 nreA T GAF domain
PGHLFOJI_01352 8.7e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PGHLFOJI_01353 0.0 sbcC L Putative exonuclease SbcCD, C subunit
PGHLFOJI_01354 5.7e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PGHLFOJI_01356 3.2e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PGHLFOJI_01358 2.1e-226 glnP P ABC transporter
PGHLFOJI_01359 3e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PGHLFOJI_01360 1.5e-250 cycA E Amino acid permease
PGHLFOJI_01361 4.2e-40
PGHLFOJI_01362 2.4e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PGHLFOJI_01363 9.3e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PGHLFOJI_01364 4.1e-231 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
PGHLFOJI_01365 1.9e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PGHLFOJI_01366 7e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
PGHLFOJI_01367 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PGHLFOJI_01368 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
PGHLFOJI_01369 3.1e-102 narJ C Nitrate reductase delta subunit
PGHLFOJI_01370 4e-127 narI 1.7.5.1 C Nitrate reductase
PGHLFOJI_01371 1.5e-82 tlpA2 L Transposase IS200 like
PGHLFOJI_01372 2.7e-238 L transposase, IS605 OrfB family
PGHLFOJI_01376 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PGHLFOJI_01377 4.2e-37 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PGHLFOJI_01378 5.3e-50 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PGHLFOJI_01379 7.1e-167 whiA K May be required for sporulation
PGHLFOJI_01380 8.4e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PGHLFOJI_01381 2.1e-160 rapZ S Displays ATPase and GTPase activities
PGHLFOJI_01382 2.2e-204
PGHLFOJI_01383 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PGHLFOJI_01384 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PGHLFOJI_01386 8.9e-41 ywkB S Membrane transport protein
PGHLFOJI_01387 7.1e-203 xerS L Belongs to the 'phage' integrase family
PGHLFOJI_01388 3.2e-180 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PGHLFOJI_01389 2e-169 4.4.1.8 E Aminotransferase, class I
PGHLFOJI_01390 7.9e-44 4.4.1.8 E Aminotransferase, class I
PGHLFOJI_01391 6.9e-195 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
PGHLFOJI_01392 9.8e-180 C Zinc-binding dehydrogenase
PGHLFOJI_01393 3.1e-102 proW P ABC transporter, permease protein
PGHLFOJI_01394 3.6e-140 proV E ABC transporter, ATP-binding protein
PGHLFOJI_01395 1.8e-108 proWZ P ABC transporter permease
PGHLFOJI_01396 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
PGHLFOJI_01397 4.7e-76 K Transcriptional regulator
PGHLFOJI_01398 1e-72 O OsmC-like protein
PGHLFOJI_01399 2.8e-75 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PGHLFOJI_01400 1.4e-22 EGP Major Facilitator Superfamily
PGHLFOJI_01401 2.2e-165 L PFAM Integrase catalytic region
PGHLFOJI_01402 3.3e-86 L Helix-turn-helix domain
PGHLFOJI_01403 1.3e-162 mleR K LysR family transcriptional regulator
PGHLFOJI_01404 9.5e-250 yjjP S Putative threonine/serine exporter
PGHLFOJI_01405 3e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
PGHLFOJI_01406 4.5e-188 I Alpha beta
PGHLFOJI_01407 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PGHLFOJI_01408 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PGHLFOJI_01410 5.9e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PGHLFOJI_01411 3.6e-148 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PGHLFOJI_01412 1.2e-40 S Domain of unknown function (DUF4811)
PGHLFOJI_01413 2.9e-103 dedA S SNARE-like domain protein
PGHLFOJI_01414 5.7e-25 S Protein of unknown function (DUF1461)
PGHLFOJI_01415 6.6e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PGHLFOJI_01416 2.2e-96 yutD S Protein of unknown function (DUF1027)
PGHLFOJI_01417 5.3e-110 S Calcineurin-like phosphoesterase
PGHLFOJI_01418 2.1e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PGHLFOJI_01419 2.5e-158 ytxK 2.1.1.72 L N-6 DNA Methylase
PGHLFOJI_01421 2.9e-14
PGHLFOJI_01423 2.3e-15 NU general secretion pathway protein
PGHLFOJI_01424 1.1e-47 comGC U competence protein ComGC
PGHLFOJI_01425 8.7e-158 comGB NU type II secretion system
PGHLFOJI_01426 2.7e-177 comGA NU Type II IV secretion system protein
PGHLFOJI_01427 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
PGHLFOJI_01428 1.9e-83 mltD CBM50 M PFAM NLP P60 protein
PGHLFOJI_01429 3.7e-134 yebC K Transcriptional regulatory protein
PGHLFOJI_01430 3.6e-85
PGHLFOJI_01431 2.2e-185 ccpA K catabolite control protein A
PGHLFOJI_01432 4.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PGHLFOJI_01433 4.9e-70
PGHLFOJI_01434 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PGHLFOJI_01435 2e-155 ykuT M mechanosensitive ion channel
PGHLFOJI_01436 1.7e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
PGHLFOJI_01437 8.8e-95 S Phosphoesterase
PGHLFOJI_01438 3.6e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PGHLFOJI_01439 6.3e-148 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PGHLFOJI_01440 3e-93 yslB S Protein of unknown function (DUF2507)
PGHLFOJI_01441 1.2e-225 clcA_2 P Chloride transporter, ClC family
PGHLFOJI_01442 1e-53 trxA O Belongs to the thioredoxin family
PGHLFOJI_01443 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PGHLFOJI_01444 4.7e-91 cvpA S Colicin V production protein
PGHLFOJI_01445 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGHLFOJI_01446 5.7e-33 yrzB S Belongs to the UPF0473 family
PGHLFOJI_01447 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PGHLFOJI_01448 1.2e-42 yrzL S Belongs to the UPF0297 family
PGHLFOJI_01449 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGHLFOJI_01450 4.2e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PGHLFOJI_01451 3.4e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PGHLFOJI_01452 5.5e-42 yajC U Preprotein translocase
PGHLFOJI_01453 2.2e-176 2.4.2.29 F queuine tRNA-ribosyltransferase activity
PGHLFOJI_01454 3.2e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PGHLFOJI_01455 1.9e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PGHLFOJI_01456 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PGHLFOJI_01457 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PGHLFOJI_01458 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
PGHLFOJI_01459 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PGHLFOJI_01460 1.9e-231 cinA 3.5.1.42 S Belongs to the CinA family
PGHLFOJI_01461 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGHLFOJI_01462 1.8e-96 ymfM S Helix-turn-helix domain
PGHLFOJI_01463 4.9e-251 ymfH S Peptidase M16
PGHLFOJI_01464 1.2e-230 ymfF S Peptidase M16 inactive domain protein
PGHLFOJI_01465 2.4e-161 aatB ET ABC transporter substrate-binding protein
PGHLFOJI_01466 4.8e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PGHLFOJI_01467 1.4e-108 glnP P ABC transporter permease
PGHLFOJI_01468 6.6e-93 mreD M rod shape-determining protein MreD
PGHLFOJI_01469 1.4e-145 mreC M Involved in formation and maintenance of cell shape
PGHLFOJI_01470 1.9e-181 mreB D cell shape determining protein MreB
PGHLFOJI_01471 9.4e-115 radC L DNA repair protein
PGHLFOJI_01472 1.9e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PGHLFOJI_01473 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PGHLFOJI_01474 1.6e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PGHLFOJI_01477 1.8e-30 S zinc-ribbon domain
PGHLFOJI_01478 1.1e-40
PGHLFOJI_01479 2.1e-36 M LysM domain
PGHLFOJI_01480 2.3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PGHLFOJI_01481 6.1e-209 EG GntP family permease
PGHLFOJI_01482 4.4e-46 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PGHLFOJI_01483 1.2e-60 azlD S branched-chain amino acid
PGHLFOJI_01484 2.6e-139 azlC E AzlC protein
PGHLFOJI_01485 1.1e-202 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PGHLFOJI_01486 5.9e-208 hpk31 2.7.13.3 T Histidine kinase
PGHLFOJI_01487 1e-122 K response regulator
PGHLFOJI_01488 4.8e-93 S Cupin superfamily (DUF985)
PGHLFOJI_01491 4.8e-162 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PGHLFOJI_01492 3.6e-196 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PGHLFOJI_01493 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PGHLFOJI_01494 1.1e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PGHLFOJI_01495 2.8e-191 cps2I S Psort location CytoplasmicMembrane, score
PGHLFOJI_01496 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
PGHLFOJI_01497 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PGHLFOJI_01498 3.6e-207 carA 6.3.5.5 F Belongs to the CarA family
PGHLFOJI_01499 1e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PGHLFOJI_01500 3e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PGHLFOJI_01501 1.7e-70 esbA S Family of unknown function (DUF5322)
PGHLFOJI_01502 5.3e-71 rnhA 3.1.26.4 L Ribonuclease HI
PGHLFOJI_01503 9.7e-109 XK27_02070 S Nitroreductase family
PGHLFOJI_01504 3.6e-157 yckB ET Belongs to the bacterial solute-binding protein 3 family
PGHLFOJI_01505 1.2e-118 yecS E ABC transporter permease
PGHLFOJI_01506 8.4e-22 M Glycosyltransferase like family 2
PGHLFOJI_01507 2.9e-81 tlpA2 L Transposase IS200 like
PGHLFOJI_01508 1.9e-239 purD 6.3.4.13 F Belongs to the GARS family
PGHLFOJI_01509 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PGHLFOJI_01510 1.8e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PGHLFOJI_01511 1.9e-178
PGHLFOJI_01512 3.8e-47 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PGHLFOJI_01513 1.2e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PGHLFOJI_01514 0.0 copA 3.6.3.54 P P-type ATPase
PGHLFOJI_01515 3.1e-26 EGP Major facilitator Superfamily
PGHLFOJI_01516 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
PGHLFOJI_01517 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
PGHLFOJI_01518 1.7e-136 E GDSL-like Lipase/Acylhydrolase family
PGHLFOJI_01519 3e-124 C nitroreductase
PGHLFOJI_01520 1.3e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PGHLFOJI_01521 1.2e-11 sucD 6.2.1.5 C CoA-ligase
PGHLFOJI_01522 8.2e-96 allD 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PGHLFOJI_01523 1.4e-80 allD 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PGHLFOJI_01524 1.7e-98 allC 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M20/M25/M40
PGHLFOJI_01525 3.9e-129 allB 3.5.2.5 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PGHLFOJI_01526 2.8e-63 pucR QT Purine catabolism regulatory protein-like family
PGHLFOJI_01527 4.5e-26 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
PGHLFOJI_01528 8.9e-21 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
PGHLFOJI_01529 5e-38 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
PGHLFOJI_01530 7.6e-180 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGHLFOJI_01531 9e-31 4.4.1.8 E Aminotransferase, class I
PGHLFOJI_01532 7.3e-38 M Protein of unknown function (DUF3737)
PGHLFOJI_01533 4.4e-106 L Integrase
PGHLFOJI_01534 6.1e-71 ydjP I Alpha/beta hydrolase family
PGHLFOJI_01535 8.1e-138 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PGHLFOJI_01536 1.8e-92 citR K sugar-binding domain protein
PGHLFOJI_01537 4.8e-186 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PGHLFOJI_01539 1.8e-162 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PGHLFOJI_01541 0.0 tetP J elongation factor G
PGHLFOJI_01542 5.2e-212 S Type IV secretion-system coupling protein DNA-binding domain
PGHLFOJI_01543 8.9e-83 F Hydrolase, NUDIX family
PGHLFOJI_01544 8.5e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PGHLFOJI_01545 2.6e-15 arcD S C4-dicarboxylate anaerobic carrier
PGHLFOJI_01546 1.7e-103 arcD S C4-dicarboxylate anaerobic carrier
PGHLFOJI_01547 1.2e-272 nylA 3.5.1.4 J Belongs to the amidase family
PGHLFOJI_01549 1e-83 S Virulence-associated protein E
PGHLFOJI_01550 3.7e-143 L DNA replication protein
PGHLFOJI_01553 2.4e-16 K Cro/C1-type HTH DNA-binding domain
PGHLFOJI_01554 3.5e-205 L Belongs to the 'phage' integrase family
PGHLFOJI_01556 7.9e-79 copY K Copper transport repressor CopY TcrY
PGHLFOJI_01557 5.7e-40
PGHLFOJI_01558 4.4e-166 GK ROK family
PGHLFOJI_01559 1.1e-36 T Belongs to the universal stress protein A family
PGHLFOJI_01560 8.7e-250 mntH P H( )-stimulated, divalent metal cation uptake system
PGHLFOJI_01561 1.5e-133 L PFAM transposase, IS4 family protein
PGHLFOJI_01562 5.9e-152 glcU U sugar transport
PGHLFOJI_01563 8.2e-250 yclK 2.7.13.3 T Histidine kinase
PGHLFOJI_01564 3.7e-131 K response regulator
PGHLFOJI_01566 7e-124 K Crp-like helix-turn-helix domain
PGHLFOJI_01567 3.6e-241 larA 5.1.2.1 S Domain of unknown function (DUF2088)
PGHLFOJI_01568 1.7e-131 cpmA S AIR carboxylase
PGHLFOJI_01569 2.4e-216 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PGHLFOJI_01570 4.5e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PGHLFOJI_01571 2.2e-148 larE S NAD synthase
PGHLFOJI_01572 6.2e-185 hoxN U High-affinity nickel-transport protein
PGHLFOJI_01573 1.1e-89 rmeB K transcriptional regulator, MerR family
PGHLFOJI_01574 3.6e-49 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
PGHLFOJI_01575 6.2e-75 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PGHLFOJI_01576 7.8e-57 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
PGHLFOJI_01578 1.2e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PGHLFOJI_01579 3.5e-260 guaD 3.5.4.3 F Amidohydrolase family
PGHLFOJI_01580 1.5e-93 tdh 1.1.1.14 C Zinc-binding dehydrogenase
PGHLFOJI_01581 0.0 FbpA K Fibronectin-binding protein
PGHLFOJI_01582 3.2e-161 degV S EDD domain protein, DegV family
PGHLFOJI_01583 3e-97
PGHLFOJI_01584 6.9e-133 S Belongs to the UPF0246 family
PGHLFOJI_01585 7.3e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PGHLFOJI_01586 5.3e-113 ylbE GM NAD(P)H-binding
PGHLFOJI_01587 3.5e-99 K Acetyltransferase (GNAT) domain
PGHLFOJI_01588 8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PGHLFOJI_01589 7.8e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PGHLFOJI_01590 2.3e-284 thrC 4.2.3.1 E Threonine synthase
PGHLFOJI_01591 6.8e-122 azlC E azaleucine resistance protein AzlC
PGHLFOJI_01592 2.8e-54 azlD E Branched-chain amino acid transport
PGHLFOJI_01593 1e-30 yphJ 4.1.1.44 S decarboxylase
PGHLFOJI_01594 1.1e-09 yphJ 4.1.1.44 S decarboxylase
PGHLFOJI_01595 1.4e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PGHLFOJI_01596 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PGHLFOJI_01597 1.4e-200 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGHLFOJI_01598 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
PGHLFOJI_01599 2.3e-195 lplA 6.3.1.20 H Lipoate-protein ligase
PGHLFOJI_01600 1.7e-215 E GDSL-like Lipase/Acylhydrolase family
PGHLFOJI_01601 3.2e-24 K LysR substrate binding domain protein
PGHLFOJI_01602 3.3e-10 K Transcriptional regulator
PGHLFOJI_01603 1e-23 K LysR substrate binding domain protein
PGHLFOJI_01604 1.7e-213 naiP EGP Major facilitator Superfamily
PGHLFOJI_01605 2.1e-32 yhdP S Transporter associated domain
PGHLFOJI_01606 1.1e-204 yhdP S Transporter associated domain
PGHLFOJI_01607 3.4e-201 mdtG EGP Major facilitator Superfamily
PGHLFOJI_01608 1.6e-159 EGP Major facilitator Superfamily
PGHLFOJI_01609 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
PGHLFOJI_01610 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGHLFOJI_01611 6.1e-126 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGHLFOJI_01612 1.1e-92 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGHLFOJI_01613 3.4e-158 S Alpha/beta hydrolase of unknown function (DUF915)
PGHLFOJI_01614 4.8e-276 pipD E Dipeptidase
PGHLFOJI_01615 1.2e-177 yjbQ P TrkA C-terminal domain protein
PGHLFOJI_01616 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PGHLFOJI_01617 3.9e-284 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PGHLFOJI_01619 0.0 kup P Transport of potassium into the cell
PGHLFOJI_01620 4.6e-49
PGHLFOJI_01621 0.0 S Bacterial membrane protein YfhO
PGHLFOJI_01623 5.9e-237 lmrB EGP Major facilitator Superfamily
PGHLFOJI_01624 5.5e-158 S Alpha beta hydrolase
PGHLFOJI_01625 6.5e-90 1.6.5.2 GM NAD(P)H-binding
PGHLFOJI_01626 6.3e-45 1.6.5.2 GM NAD(P)H-binding
PGHLFOJI_01627 2.5e-152 S Sucrose-6F-phosphate phosphohydrolase
PGHLFOJI_01630 1.2e-240 dtpT U amino acid peptide transporter
PGHLFOJI_01632 6.4e-213 ydiN G Major Facilitator Superfamily
PGHLFOJI_01633 4.9e-12 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
PGHLFOJI_01634 2.5e-214 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PGHLFOJI_01635 1.5e-197 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PGHLFOJI_01636 7.4e-89 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PGHLFOJI_01637 1e-215 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
PGHLFOJI_01638 2.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGHLFOJI_01639 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PGHLFOJI_01640 6.4e-157 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PGHLFOJI_01641 6.7e-23 S Virus attachment protein p12 family
PGHLFOJI_01642 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PGHLFOJI_01643 1.4e-33 feoA P FeoA domain
PGHLFOJI_01644 8.5e-145 sufC O FeS assembly ATPase SufC
PGHLFOJI_01645 3.8e-243 sufD O FeS assembly protein SufD
PGHLFOJI_01646 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PGHLFOJI_01647 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
PGHLFOJI_01648 9.3e-272 sufB O assembly protein SufB
PGHLFOJI_01649 4.7e-183 fecB P Periplasmic binding protein
PGHLFOJI_01650 6.3e-143 ET Bacterial periplasmic substrate-binding proteins
PGHLFOJI_01651 8.8e-64 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PGHLFOJI_01652 1.4e-25 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PGHLFOJI_01653 1.2e-07 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PGHLFOJI_01654 1.7e-226 aadAT EK Aminotransferase, class I
PGHLFOJI_01655 6.2e-13
PGHLFOJI_01656 2.1e-50 L hmm pf00665
PGHLFOJI_01657 2.9e-62 K helix_turn_helix multiple antibiotic resistance protein
PGHLFOJI_01658 3e-100 M domain protein
PGHLFOJI_01659 2.3e-153 lsgF M Glycosyl transferase family 2
PGHLFOJI_01660 4.3e-152
PGHLFOJI_01661 3.4e-241 M Teichoic acid biosynthesis protein
PGHLFOJI_01662 2.2e-190 V Glycosyl transferase, family 2
PGHLFOJI_01663 1.7e-18 S EpsG family
PGHLFOJI_01664 2.2e-162 GT2 S Glycosyl transferase family 2
PGHLFOJI_01665 6.4e-70 cps2I S Psort location CytoplasmicMembrane, score
PGHLFOJI_01667 8.3e-298 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGHLFOJI_01668 7e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
PGHLFOJI_01669 1.6e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGHLFOJI_01670 7.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PGHLFOJI_01671 1.2e-121 iolS C Aldo keto reductase
PGHLFOJI_01672 1.9e-20 brnQ U Component of the transport system for branched-chain amino acids
PGHLFOJI_01673 9.8e-77
PGHLFOJI_01676 2.4e-133 L hmm pf00665
PGHLFOJI_01677 1.9e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
PGHLFOJI_01678 2.8e-221 S Phage capsid family
PGHLFOJI_01679 4.3e-43 S Phage gp6-like head-tail connector protein
PGHLFOJI_01680 6.9e-68 S Phage head-tail joining protein
PGHLFOJI_01681 1.4e-69 S Bacteriophage holin family
PGHLFOJI_01682 2.4e-132 M Glycosyl hydrolases family 25
PGHLFOJI_01683 2.4e-18
PGHLFOJI_01684 7.2e-39 L Recombinase zinc beta ribbon domain
PGHLFOJI_01685 2.7e-97 yfbR S HD containing hydrolase-like enzyme
PGHLFOJI_01686 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PGHLFOJI_01687 3.1e-136 cof S haloacid dehalogenase-like hydrolase
PGHLFOJI_01688 1.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PGHLFOJI_01689 3.8e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PGHLFOJI_01690 1.3e-188 S interspecies interaction between organisms
PGHLFOJI_01691 3.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PGHLFOJI_01692 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PGHLFOJI_01693 2.2e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PGHLFOJI_01694 1.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGHLFOJI_01695 2e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGHLFOJI_01696 1.7e-148 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGHLFOJI_01697 9.1e-95 tuaA M Bacterial sugar transferase
PGHLFOJI_01698 2.8e-131 cps2D 5.1.3.2 M RmlD substrate binding domain
PGHLFOJI_01699 3.2e-141 ywqE 3.1.3.48 GM PHP domain protein
PGHLFOJI_01700 4.2e-114 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PGHLFOJI_01701 1.8e-131 epsB M biosynthesis protein
PGHLFOJI_01702 1.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PGHLFOJI_01703 4.1e-90 L Probable transposase
PGHLFOJI_01704 3e-28 EGP Major Facilitator Superfamily
PGHLFOJI_01705 1.6e-44 EGP Major Facilitator Superfamily
PGHLFOJI_01706 1.6e-69 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PGHLFOJI_01707 6.9e-58 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PGHLFOJI_01708 3.5e-15 C Flavodoxin
PGHLFOJI_01709 4.3e-27 GM NmrA-like family
PGHLFOJI_01710 5.1e-19 S NAD(P)H dehydrogenase (quinone) activity
PGHLFOJI_01711 9.9e-100 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PGHLFOJI_01712 1.8e-75 argR K Regulates arginine biosynthesis genes
PGHLFOJI_01713 5.5e-124 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PGHLFOJI_01714 8.6e-158 hrtB V ABC transporter permease
PGHLFOJI_01715 1.1e-107 ygfC K Bacterial regulatory proteins, tetR family
PGHLFOJI_01716 6.1e-88 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
PGHLFOJI_01717 7.5e-32 L Transposase and inactivated derivatives IS30 family
PGHLFOJI_01718 3.5e-16 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PGHLFOJI_01719 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PGHLFOJI_01720 4.5e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PGHLFOJI_01721 9.4e-205 coiA 3.6.4.12 S Competence protein
PGHLFOJI_01722 1.8e-113 yjbH Q Thioredoxin
PGHLFOJI_01723 6e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
PGHLFOJI_01724 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PGHLFOJI_01725 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PGHLFOJI_01726 1.4e-195 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PGHLFOJI_01727 2.5e-163 rrmA 2.1.1.187 H Methyltransferase
PGHLFOJI_01728 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PGHLFOJI_01729 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PGHLFOJI_01730 1.2e-07 S Protein of unknown function (DUF4044)
PGHLFOJI_01731 5.8e-58
PGHLFOJI_01732 5.6e-79 mraZ K Belongs to the MraZ family
PGHLFOJI_01733 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PGHLFOJI_01734 3.5e-08 ftsL D Cell division protein FtsL
PGHLFOJI_01735 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PGHLFOJI_01736 9.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PGHLFOJI_01737 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PGHLFOJI_01738 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PGHLFOJI_01739 3.2e-150 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PGHLFOJI_01740 5.5e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PGHLFOJI_01741 5.8e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PGHLFOJI_01742 2.5e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PGHLFOJI_01743 6.8e-41 yggT S YGGT family
PGHLFOJI_01744 2.9e-145 ylmH S S4 domain protein
PGHLFOJI_01745 4.8e-112 divIVA D DivIVA domain protein
PGHLFOJI_01747 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PGHLFOJI_01748 1.2e-32 cspB K Cold shock protein
PGHLFOJI_01749 7.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PGHLFOJI_01751 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PGHLFOJI_01752 3.4e-58 XK27_04120 S Putative amino acid metabolism
PGHLFOJI_01753 4.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PGHLFOJI_01754 1.3e-306 S amidohydrolase
PGHLFOJI_01755 4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PGHLFOJI_01756 1.6e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PGHLFOJI_01757 7.1e-124 S Repeat protein
PGHLFOJI_01758 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PGHLFOJI_01759 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PGHLFOJI_01760 4.2e-74 spx4 1.20.4.1 P ArsC family
PGHLFOJI_01761 7.8e-189 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
PGHLFOJI_01762 6.5e-31 ykzG S Belongs to the UPF0356 family
PGHLFOJI_01763 9.8e-74
PGHLFOJI_01764 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PGHLFOJI_01765 2.4e-49 yktA S Belongs to the UPF0223 family
PGHLFOJI_01766 1.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PGHLFOJI_01767 0.0 typA T GTP-binding protein TypA
PGHLFOJI_01768 2e-214 ftsW D Belongs to the SEDS family
PGHLFOJI_01769 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PGHLFOJI_01770 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PGHLFOJI_01771 9.6e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PGHLFOJI_01772 6.7e-198 ylbL T Belongs to the peptidase S16 family
PGHLFOJI_01773 3.8e-90 comEA L Competence protein ComEA
PGHLFOJI_01774 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
PGHLFOJI_01775 0.0 comEC S Competence protein ComEC
PGHLFOJI_01776 1.8e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
PGHLFOJI_01777 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
PGHLFOJI_01778 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PGHLFOJI_01779 7.9e-97 L Transposase and inactivated derivatives, IS30 family
PGHLFOJI_01780 2.9e-24 L Transposase and inactivated derivatives, IS30 family
PGHLFOJI_01781 3e-184 fruR3 K Transcriptional regulator, LacI family
PGHLFOJI_01782 4.2e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
PGHLFOJI_01783 1.7e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGHLFOJI_01784 8.7e-40 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PGHLFOJI_01785 8.9e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
PGHLFOJI_01786 4.3e-217 yceI EGP Major facilitator Superfamily
PGHLFOJI_01787 2.6e-54 tnp2PF3 L Transposase
PGHLFOJI_01788 8.3e-33 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
PGHLFOJI_01789 4.2e-80 tlpA2 L Transposase IS200 like
PGHLFOJI_01790 1.2e-177 3.4.11.5 E Releases the N-terminal proline from various substrates
PGHLFOJI_01791 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
PGHLFOJI_01792 7.7e-25 S Uncharacterized protein conserved in bacteria (DUF2325)
PGHLFOJI_01793 1e-247 S Uncharacterized protein conserved in bacteria (DUF2325)
PGHLFOJI_01794 3.1e-217 lacS G Transporter
PGHLFOJI_01795 2.3e-83 lacR K Transcriptional regulator
PGHLFOJI_01797 0.0 copB 3.6.3.4 P P-type ATPase
PGHLFOJI_01798 6.5e-75 K Copper transport repressor CopY TcrY
PGHLFOJI_01799 8.1e-196 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PGHLFOJI_01800 0.0 pepN 3.4.11.2 E aminopeptidase
PGHLFOJI_01801 6.9e-161 dcm_2 2.1.1.37 L C-5 cytosine-specific DNA methylase
PGHLFOJI_01802 1.5e-153 dcm 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
PGHLFOJI_01803 1e-76 L NgoFVII restriction endonuclease
PGHLFOJI_01820 2.1e-135 L Transposase and inactivated derivatives, IS30 family
PGHLFOJI_01824 2.1e-61 3.2.1.23 S Domain of unknown function DUF302
PGHLFOJI_01825 9.8e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PGHLFOJI_01826 1.1e-272 pepV 3.5.1.18 E dipeptidase PepV
PGHLFOJI_01827 5.1e-87 uspA T Belongs to the universal stress protein A family
PGHLFOJI_01828 1.7e-241 cycA E Amino acid permease
PGHLFOJI_01829 1.1e-253 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
PGHLFOJI_01830 2.8e-61 rplQ J Ribosomal protein L17
PGHLFOJI_01831 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGHLFOJI_01832 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PGHLFOJI_01833 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PGHLFOJI_01834 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PGHLFOJI_01835 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PGHLFOJI_01836 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PGHLFOJI_01837 5.8e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PGHLFOJI_01838 2.1e-65 rplO J Binds to the 23S rRNA
PGHLFOJI_01839 2.5e-23 rpmD J Ribosomal protein L30
PGHLFOJI_01840 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PGHLFOJI_01841 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PGHLFOJI_01842 1.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PGHLFOJI_01843 3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PGHLFOJI_01844 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGHLFOJI_01845 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PGHLFOJI_01846 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PGHLFOJI_01847 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PGHLFOJI_01848 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PGHLFOJI_01849 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
PGHLFOJI_01850 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PGHLFOJI_01851 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PGHLFOJI_01852 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PGHLFOJI_01853 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PGHLFOJI_01854 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PGHLFOJI_01855 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PGHLFOJI_01856 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
PGHLFOJI_01857 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PGHLFOJI_01858 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PGHLFOJI_01859 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PGHLFOJI_01860 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PGHLFOJI_01861 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PGHLFOJI_01862 2.1e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
PGHLFOJI_01863 1.5e-118 ykiI
PGHLFOJI_01864 1.6e-85 ykiI
PGHLFOJI_01865 5.6e-135 puuD S peptidase C26
PGHLFOJI_01866 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGHLFOJI_01867 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGHLFOJI_01868 5.8e-106 K Bacterial regulatory proteins, tetR family
PGHLFOJI_01869 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PGHLFOJI_01870 4.8e-79 ctsR K Belongs to the CtsR family
PGHLFOJI_01871 9.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
PGHLFOJI_01872 1.9e-132 XK27_07210 6.1.1.6 S B3 4 domain
PGHLFOJI_01873 2.7e-120 J 2'-5' RNA ligase superfamily
PGHLFOJI_01875 7.7e-39 S ABC-type cobalt transport system, permease component
PGHLFOJI_01876 1.2e-16 S ABC-type cobalt transport system, permease component
PGHLFOJI_01877 2.5e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PGHLFOJI_01878 1.7e-45 IQ reductase
PGHLFOJI_01879 4.5e-11 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHLFOJI_01885 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PGHLFOJI_01886 3.9e-268 lysP E amino acid
PGHLFOJI_01888 1.3e-156 I alpha/beta hydrolase fold
PGHLFOJI_01889 2e-115 lssY 3.6.1.27 I phosphatase
PGHLFOJI_01890 2.8e-82 S Threonine/Serine exporter, ThrE
PGHLFOJI_01891 6.3e-126 thrE S Putative threonine/serine exporter
PGHLFOJI_01892 3.3e-29 cspA K Cold shock protein
PGHLFOJI_01893 4.4e-123 sirR K iron dependent repressor
PGHLFOJI_01894 1.6e-163 czcD P cation diffusion facilitator family transporter
PGHLFOJI_01895 1e-114 S membrane
PGHLFOJI_01896 1.1e-108 S VIT family
PGHLFOJI_01897 2.9e-81 usp1 T Belongs to the universal stress protein A family
PGHLFOJI_01898 8.1e-33 elaA S GNAT family
PGHLFOJI_01899 6.9e-215 S CAAX protease self-immunity
PGHLFOJI_01900 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGHLFOJI_01901 4.4e-58
PGHLFOJI_01902 1.9e-74 merR K MerR HTH family regulatory protein
PGHLFOJI_01903 5.6e-267 lmrB EGP Major facilitator Superfamily
PGHLFOJI_01904 2.7e-46 S Domain of unknown function (DUF4811)
PGHLFOJI_01905 1e-102 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PGHLFOJI_01906 5.3e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PGHLFOJI_01907 2.9e-161 hrtB V ABC transporter permease
PGHLFOJI_01908 8e-54 yitW S Iron-sulfur cluster assembly protein
PGHLFOJI_01909 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
PGHLFOJI_01910 1.2e-257 XK27_04775 S PAS domain
PGHLFOJI_01911 2.4e-142 EG EamA-like transporter family
PGHLFOJI_01912 0.0 trxB2 1.8.1.9 C Thioredoxin domain
PGHLFOJI_01913 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
PGHLFOJI_01914 6e-194 L Belongs to the 'phage' integrase family
PGHLFOJI_01915 6.6e-66
PGHLFOJI_01917 7.6e-88 L PFAM Integrase, catalytic core
PGHLFOJI_01918 8.3e-100 L hmm pf00665
PGHLFOJI_01920 1.8e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PGHLFOJI_01921 1e-24 phaG GT1 I carboxylic ester hydrolase activity
PGHLFOJI_01922 1.2e-62 K Transcriptional regulator
PGHLFOJI_01923 8.6e-38 L hmm pf00665
PGHLFOJI_01924 2.3e-83 L Transposase
PGHLFOJI_01925 6e-47 L Integrase core domain
PGHLFOJI_01926 7.3e-52 L Transposase
PGHLFOJI_01927 6.8e-20 L PFAM transposase, IS4 family protein
PGHLFOJI_01928 3.3e-75 L PFAM transposase, IS4 family protein
PGHLFOJI_01929 9e-47 ubiE Q Methyltransferase domain
PGHLFOJI_01930 1.2e-21
PGHLFOJI_01931 2.9e-50 4.4.1.8 E Aminotransferase, class I
PGHLFOJI_01932 3.7e-33 4.4.1.8 E Aminotransferase, class I
PGHLFOJI_01933 3.1e-256 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
PGHLFOJI_01934 3.8e-16
PGHLFOJI_01935 6e-12 S Transglycosylase associated protein
PGHLFOJI_01936 1e-69 S Asp23 family, cell envelope-related function
PGHLFOJI_01937 8.8e-88
PGHLFOJI_01938 3.7e-38 L Transposase and inactivated derivatives
PGHLFOJI_01939 3.3e-155 L COG2801 Transposase and inactivated derivatives
PGHLFOJI_01940 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PGHLFOJI_01941 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PGHLFOJI_01942 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PGHLFOJI_01943 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PGHLFOJI_01944 1.1e-155 recO L Involved in DNA repair and RecF pathway recombination
PGHLFOJI_01945 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PGHLFOJI_01946 1e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PGHLFOJI_01947 1.7e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PGHLFOJI_01948 1.1e-178 phoH T phosphate starvation-inducible protein PhoH
PGHLFOJI_01949 4.6e-71 yqeY S YqeY-like protein
PGHLFOJI_01950 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PGHLFOJI_01951 5.1e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
PGHLFOJI_01952 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PGHLFOJI_01953 1.3e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
PGHLFOJI_01954 6.1e-196 6.3.1.20 H Lipoate-protein ligase
PGHLFOJI_01955 3.7e-174 lytH 3.5.1.28 M Ami_3
PGHLFOJI_01956 1.4e-169 yniA G Phosphotransferase enzyme family
PGHLFOJI_01957 4.6e-174 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PGHLFOJI_01958 5.2e-246 mmuP E amino acid
PGHLFOJI_01959 3.8e-156 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PGHLFOJI_01960 8.1e-213 hom1 1.1.1.3 E Homoserine dehydrogenase
PGHLFOJI_01962 6.1e-137 IQ KR domain
PGHLFOJI_01963 3.1e-153 cjaA ET ABC transporter substrate-binding protein
PGHLFOJI_01964 3.9e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PGHLFOJI_01965 4.5e-115 P ABC transporter permease
PGHLFOJI_01966 5.4e-113 papP P ABC transporter, permease protein
PGHLFOJI_01968 1.1e-90 yxeQ S MmgE/PrpD family
PGHLFOJI_01969 1.6e-170 pcaB 4.3.2.2 F Adenylosuccinate lyase C-terminus
PGHLFOJI_01970 1.5e-145 3.5.1.47 E Peptidase dimerisation domain
PGHLFOJI_01971 1.2e-78 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
PGHLFOJI_01972 2.2e-70 yxeN U ABC transporter, permease protein
PGHLFOJI_01973 5.4e-47 yxeL K acetyltransferase
PGHLFOJI_01974 2e-66 yxeM ET Bacterial periplasmic substrate-binding proteins
PGHLFOJI_01976 7.4e-211 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PGHLFOJI_01977 1.9e-44 metC1 2.5.1.48, 4.4.1.8 E cystathionine
PGHLFOJI_01978 6e-163 metC1 2.5.1.48, 4.4.1.8 E cystathionine
PGHLFOJI_01979 3.5e-85 slyA K Transcriptional regulator
PGHLFOJI_01980 2.7e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PGHLFOJI_01981 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PGHLFOJI_01982 4.4e-58
PGHLFOJI_01983 1.2e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PGHLFOJI_01984 5.2e-181 prmA J Ribosomal protein L11 methyltransferase
PGHLFOJI_01985 1.2e-54
PGHLFOJI_01987 1.5e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PGHLFOJI_01988 3.2e-97 S integral membrane protein
PGHLFOJI_01990 1.8e-34 aes I Carboxylesterase family
PGHLFOJI_01991 1.8e-32 aes I Hydrolase, alpha beta domain protein
PGHLFOJI_01993 4.7e-219 L Integrase core domain
PGHLFOJI_01994 9e-125 O Bacterial dnaA protein
PGHLFOJI_01995 3.8e-28 L Helix-turn-helix domain
PGHLFOJI_01996 7.2e-121 L hmm pf00665
PGHLFOJI_01997 4.4e-49 tnp L MULE transposase domain
PGHLFOJI_01998 2.2e-111 ybbL S ABC transporter, ATP-binding protein
PGHLFOJI_01999 3.3e-133 ybbM S Uncharacterised protein family (UPF0014)
PGHLFOJI_02000 1.1e-103 2.3.1.128 K acetyltransferase
PGHLFOJI_02001 2e-174 coaA 2.7.1.33 F Pantothenic acid kinase
PGHLFOJI_02002 2.2e-51 L Helix-turn-helix domain
PGHLFOJI_02003 6.2e-85 L hmm pf00665
PGHLFOJI_02004 1.1e-52 trxA O Belongs to the thioredoxin family
PGHLFOJI_02005 1e-120 mleP3 S Membrane transport protein
PGHLFOJI_02008 4.6e-188 L PFAM Integrase, catalytic core

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)