ORF_ID e_value Gene_name EC_number CAZy COGs Description
MDIOCMKF_00001 1.1e-110 L PFAM Integrase catalytic
MDIOCMKF_00002 1.4e-158 lysR5 K LysR substrate binding domain
MDIOCMKF_00003 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
MDIOCMKF_00004 3e-251 G Major Facilitator
MDIOCMKF_00005 1.6e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDIOCMKF_00006 9.4e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDIOCMKF_00007 9.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDIOCMKF_00008 1.1e-278 yjeM E Amino Acid
MDIOCMKF_00009 3e-08
MDIOCMKF_00011 2.7e-97 M lysozyme activity
MDIOCMKF_00014 3.7e-08
MDIOCMKF_00017 6.7e-113 S N-acetylmuramoyl-L-alanine amidase activity
MDIOCMKF_00018 3.3e-212 S Phage minor structural protein
MDIOCMKF_00019 1.5e-119 S Phage tail protein
MDIOCMKF_00020 0.0 M Phage tail tape measure protein TP901
MDIOCMKF_00022 2.1e-08 S Pfam:Phage_TTP_1
MDIOCMKF_00026 1.1e-36 S Phage gp6-like head-tail connector protein
MDIOCMKF_00027 7.3e-209 S peptidase activity
MDIOCMKF_00028 3.4e-113 S Clp protease
MDIOCMKF_00029 3e-162 S Phage portal protein
MDIOCMKF_00031 1.4e-227 S Phage Terminase
MDIOCMKF_00033 4.6e-66 L Phage terminase, small subunit
MDIOCMKF_00034 3e-87 S HNH endonuclease
MDIOCMKF_00035 1.9e-75 arpU S Phage transcriptional regulator, ArpU family
MDIOCMKF_00037 1e-42 L Belongs to the 'phage' integrase family
MDIOCMKF_00038 4e-07
MDIOCMKF_00041 2.4e-88 L Psort location Cytoplasmic, score
MDIOCMKF_00044 5.5e-33
MDIOCMKF_00052 1.2e-17
MDIOCMKF_00053 7e-13
MDIOCMKF_00055 1.7e-15 K Cro/C1-type HTH DNA-binding domain
MDIOCMKF_00057 9.6e-30
MDIOCMKF_00058 1.4e-106 K BRO family, N-terminal domain
MDIOCMKF_00059 2e-30 K Protein of unknown function (DUF739)
MDIOCMKF_00060 3.3e-79 3.4.21.88 K Peptidase S24-like
MDIOCMKF_00062 5.3e-46 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDIOCMKF_00064 3.9e-09
MDIOCMKF_00065 5.8e-37
MDIOCMKF_00066 1.7e-33 S Domain of unknown function (DUF4393)
MDIOCMKF_00068 6.4e-38 S Phage integrase family
MDIOCMKF_00069 3.7e-104 S Phage integrase family
MDIOCMKF_00070 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDIOCMKF_00071 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MDIOCMKF_00072 9.3e-124 srtA 3.4.22.70 M sortase family
MDIOCMKF_00073 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDIOCMKF_00074 4.5e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDIOCMKF_00075 0.0 dnaK O Heat shock 70 kDa protein
MDIOCMKF_00076 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDIOCMKF_00077 2.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDIOCMKF_00078 6.7e-121 S GyrI-like small molecule binding domain
MDIOCMKF_00079 1.6e-282 lsa S ABC transporter
MDIOCMKF_00080 7.6e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MDIOCMKF_00081 1.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDIOCMKF_00082 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDIOCMKF_00083 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDIOCMKF_00084 6e-46 rplGA J ribosomal protein
MDIOCMKF_00085 2e-46 ylxR K Protein of unknown function (DUF448)
MDIOCMKF_00086 1.1e-217 nusA K Participates in both transcription termination and antitermination
MDIOCMKF_00087 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
MDIOCMKF_00088 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDIOCMKF_00089 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDIOCMKF_00090 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MDIOCMKF_00091 3.4e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MDIOCMKF_00092 5.5e-135 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDIOCMKF_00093 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDIOCMKF_00094 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MDIOCMKF_00095 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDIOCMKF_00096 2.8e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
MDIOCMKF_00097 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
MDIOCMKF_00098 9.8e-117 plsC 2.3.1.51 I Acyltransferase
MDIOCMKF_00099 8.6e-201 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MDIOCMKF_00100 6.1e-300 mdlB V ABC transporter
MDIOCMKF_00101 0.0 mdlA V ABC transporter
MDIOCMKF_00102 1.5e-30 yneF S Uncharacterised protein family (UPF0154)
MDIOCMKF_00103 1.5e-34 ynzC S UPF0291 protein
MDIOCMKF_00104 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDIOCMKF_00105 1.1e-115 ung2 3.2.2.27 L Uracil-DNA glycosylase
MDIOCMKF_00106 6.5e-75 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MDIOCMKF_00107 9.3e-118 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MDIOCMKF_00108 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDIOCMKF_00109 2.2e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MDIOCMKF_00110 7.4e-97 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDIOCMKF_00111 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MDIOCMKF_00112 1.4e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDIOCMKF_00113 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDIOCMKF_00114 1.6e-287 pipD E Dipeptidase
MDIOCMKF_00115 7.8e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDIOCMKF_00116 0.0 smc D Required for chromosome condensation and partitioning
MDIOCMKF_00117 1.6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDIOCMKF_00118 0.0 oppA E ABC transporter substrate-binding protein
MDIOCMKF_00119 2.8e-298 oppA E ABC transporter substrate-binding protein
MDIOCMKF_00120 3.2e-30 oppA E ABC transporter substrate-binding protein
MDIOCMKF_00121 2.1e-163 oppC P Binding-protein-dependent transport system inner membrane component
MDIOCMKF_00122 7.5e-180 oppB P ABC transporter permease
MDIOCMKF_00123 4.4e-180 oppF P Belongs to the ABC transporter superfamily
MDIOCMKF_00124 1.1e-192 oppD P Belongs to the ABC transporter superfamily
MDIOCMKF_00125 2.6e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDIOCMKF_00126 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDIOCMKF_00127 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDIOCMKF_00128 9.6e-308 yloV S DAK2 domain fusion protein YloV
MDIOCMKF_00129 1.4e-57 asp S Asp23 family, cell envelope-related function
MDIOCMKF_00130 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MDIOCMKF_00131 1e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
MDIOCMKF_00132 5.9e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MDIOCMKF_00133 1.4e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDIOCMKF_00134 0.0 KLT serine threonine protein kinase
MDIOCMKF_00135 4.5e-140 stp 3.1.3.16 T phosphatase
MDIOCMKF_00136 1.2e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDIOCMKF_00137 7.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDIOCMKF_00138 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDIOCMKF_00139 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDIOCMKF_00140 4.7e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MDIOCMKF_00141 4.6e-48
MDIOCMKF_00142 5e-264 recN L May be involved in recombinational repair of damaged DNA
MDIOCMKF_00143 3.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MDIOCMKF_00144 7.8e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDIOCMKF_00145 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDIOCMKF_00146 3.6e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDIOCMKF_00147 8.1e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDIOCMKF_00148 8e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDIOCMKF_00149 3.7e-73 yqhY S Asp23 family, cell envelope-related function
MDIOCMKF_00150 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDIOCMKF_00151 9.5e-195 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MDIOCMKF_00152 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MDIOCMKF_00153 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MDIOCMKF_00154 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
MDIOCMKF_00155 1.2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDIOCMKF_00156 6.3e-246 S Uncharacterized protein conserved in bacteria (DUF2325)
MDIOCMKF_00157 1.2e-12
MDIOCMKF_00158 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MDIOCMKF_00159 1.2e-92 S ECF-type riboflavin transporter, S component
MDIOCMKF_00160 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MDIOCMKF_00161 1.4e-59
MDIOCMKF_00162 5.2e-56 K Acetyltransferase (GNAT) domain
MDIOCMKF_00163 1.3e-285 S Predicted membrane protein (DUF2207)
MDIOCMKF_00164 9.3e-08
MDIOCMKF_00165 9.3e-80
MDIOCMKF_00166 4.9e-67 S Putative adhesin
MDIOCMKF_00167 5e-79 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDIOCMKF_00168 3.6e-78 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDIOCMKF_00169 2.4e-22 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDIOCMKF_00170 7.1e-40
MDIOCMKF_00171 3.3e-185 yfdV S Membrane transport protein
MDIOCMKF_00172 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MDIOCMKF_00173 1.8e-272 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDIOCMKF_00174 1.3e-93
MDIOCMKF_00175 3.9e-98 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDIOCMKF_00176 3.1e-58 yjdF S Protein of unknown function (DUF2992)
MDIOCMKF_00177 2.1e-50 S Domain of unknown function (DUF4160)
MDIOCMKF_00178 7.9e-51
MDIOCMKF_00180 5.7e-44 yjdF S Protein of unknown function (DUF2992)
MDIOCMKF_00181 1.8e-112 1.6.5.2 S Flavodoxin-like fold
MDIOCMKF_00182 6.5e-93 K Bacterial regulatory proteins, tetR family
MDIOCMKF_00183 3.6e-67 doc S Fic/DOC family
MDIOCMKF_00184 4.1e-37
MDIOCMKF_00185 5.5e-133 K Helix-turn-helix
MDIOCMKF_00187 1.6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MDIOCMKF_00188 6.6e-134 K DNA-binding helix-turn-helix protein
MDIOCMKF_00189 5.3e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDIOCMKF_00190 6e-236 pbuX F xanthine permease
MDIOCMKF_00191 2.2e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDIOCMKF_00192 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDIOCMKF_00193 1.3e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDIOCMKF_00194 6e-73 S Domain of unknown function (DUF1934)
MDIOCMKF_00195 3.3e-266 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDIOCMKF_00196 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
MDIOCMKF_00197 9.7e-155 malG P ABC transporter permease
MDIOCMKF_00198 1.4e-253 malF P Binding-protein-dependent transport system inner membrane component
MDIOCMKF_00199 5e-229 malE G Bacterial extracellular solute-binding protein
MDIOCMKF_00200 3.6e-210 msmX P Belongs to the ABC transporter superfamily
MDIOCMKF_00201 7.1e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MDIOCMKF_00202 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MDIOCMKF_00203 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MDIOCMKF_00204 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
MDIOCMKF_00205 1.2e-174 yvdE K helix_turn _helix lactose operon repressor
MDIOCMKF_00206 2.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDIOCMKF_00207 1.1e-219 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDIOCMKF_00208 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MDIOCMKF_00209 7.4e-36 veg S Biofilm formation stimulator VEG
MDIOCMKF_00210 4.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDIOCMKF_00211 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDIOCMKF_00212 6.1e-148 tatD L hydrolase, TatD family
MDIOCMKF_00213 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDIOCMKF_00214 6.1e-92 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MDIOCMKF_00215 4.7e-100 S TPM domain
MDIOCMKF_00216 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
MDIOCMKF_00217 2.6e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDIOCMKF_00218 2.3e-113 E Belongs to the SOS response-associated peptidase family
MDIOCMKF_00220 1.3e-114
MDIOCMKF_00221 1.9e-158 ypbG 2.7.1.2 GK ROK family
MDIOCMKF_00222 1.2e-282 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDIOCMKF_00223 1.7e-268 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDIOCMKF_00224 2e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MDIOCMKF_00225 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MDIOCMKF_00226 1e-133 gmuR K UTRA
MDIOCMKF_00227 5.6e-117 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDIOCMKF_00228 6.4e-167 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDIOCMKF_00229 3.4e-42 S Domain of unknown function (DUF3284)
MDIOCMKF_00230 1.4e-127 yydK K UTRA
MDIOCMKF_00231 1.4e-248 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDIOCMKF_00232 3.4e-56
MDIOCMKF_00233 3.4e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDIOCMKF_00234 9.5e-77 hsp O Belongs to the small heat shock protein (HSP20) family
MDIOCMKF_00235 2.7e-36
MDIOCMKF_00236 1.8e-292 hsdM 2.1.1.72 V type I restriction-modification system
MDIOCMKF_00237 4.1e-119 3.1.21.3 V Type I restriction modification DNA specificity domain
MDIOCMKF_00238 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
MDIOCMKF_00239 0.0 S Protein of unknown function DUF262
MDIOCMKF_00240 0.0 1.3.5.4 C FMN_bind
MDIOCMKF_00241 7.2e-92
MDIOCMKF_00242 9.2e-109
MDIOCMKF_00243 3.8e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDIOCMKF_00244 6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDIOCMKF_00245 7.6e-115 hlyIII S protein, hemolysin III
MDIOCMKF_00246 3.8e-151 DegV S Uncharacterised protein, DegV family COG1307
MDIOCMKF_00247 2e-35 yozE S Belongs to the UPF0346 family
MDIOCMKF_00248 1.1e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MDIOCMKF_00249 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDIOCMKF_00250 9.8e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDIOCMKF_00251 5.8e-152 dprA LU DNA protecting protein DprA
MDIOCMKF_00252 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDIOCMKF_00253 1.8e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDIOCMKF_00254 2e-169 xerC D Phage integrase, N-terminal SAM-like domain
MDIOCMKF_00255 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDIOCMKF_00256 2e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDIOCMKF_00257 4.2e-177 lacX 5.1.3.3 G Aldose 1-epimerase
MDIOCMKF_00258 2.6e-98 K LysR substrate binding domain
MDIOCMKF_00259 1.6e-97 S LexA-binding, inner membrane-associated putative hydrolase
MDIOCMKF_00260 8.9e-62
MDIOCMKF_00261 1.1e-179 MA20_14895 S Conserved hypothetical protein 698
MDIOCMKF_00262 2.2e-69 K Transcriptional regulator
MDIOCMKF_00263 5.4e-47
MDIOCMKF_00264 2.6e-42
MDIOCMKF_00265 1.8e-41 K peptidyl-tyrosine sulfation
MDIOCMKF_00266 1.7e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_00267 2e-74 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_00269 2.1e-109 ybbL S ABC transporter, ATP-binding protein
MDIOCMKF_00270 1.5e-130 ybbM S Uncharacterised protein family (UPF0014)
MDIOCMKF_00271 2.1e-96 K Acetyltransferase (GNAT) domain
MDIOCMKF_00272 3.7e-51 S Protein of unknown function (DUF3021)
MDIOCMKF_00273 8.7e-75 K LytTr DNA-binding domain
MDIOCMKF_00274 6.2e-104 S Protein of unknown function (DUF1211)
MDIOCMKF_00275 8.2e-25 L Transposase
MDIOCMKF_00276 5.5e-228 S domain, Protein
MDIOCMKF_00277 8.8e-66 S domain, Protein
MDIOCMKF_00279 3.9e-23 bamA UW LPXTG-motif cell wall anchor domain protein
MDIOCMKF_00280 0.0 bamA UW LPXTG-motif cell wall anchor domain protein
MDIOCMKF_00281 0.0 M domain protein
MDIOCMKF_00282 4.1e-301
MDIOCMKF_00283 1.8e-110 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MDIOCMKF_00284 3.9e-113 3.6.1.55 F NUDIX domain
MDIOCMKF_00285 5.8e-63 S Putative adhesin
MDIOCMKF_00286 9.2e-248 brnQ U Component of the transport system for branched-chain amino acids
MDIOCMKF_00287 1.4e-11 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDIOCMKF_00288 2.7e-32 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MDIOCMKF_00289 4.5e-17 L Plasmid pRiA4b ORF-3-like protein
MDIOCMKF_00290 5.2e-68 K HxlR family
MDIOCMKF_00291 2.7e-48
MDIOCMKF_00292 5.1e-231 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
MDIOCMKF_00293 2.5e-11 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MDIOCMKF_00294 3e-76 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MDIOCMKF_00295 3e-181 dnaQ 2.7.7.7 L EXOIII
MDIOCMKF_00296 7.5e-141 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MDIOCMKF_00297 1.3e-111 yviA S Protein of unknown function (DUF421)
MDIOCMKF_00298 6.4e-73 S Protein of unknown function (DUF3290)
MDIOCMKF_00299 8.8e-245 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MDIOCMKF_00300 1.1e-78 S PAS domain
MDIOCMKF_00301 3.9e-110 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
MDIOCMKF_00303 1e-193 pts36C G iic component
MDIOCMKF_00304 2.1e-09 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MDIOCMKF_00305 3.5e-50 pts36A 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MDIOCMKF_00306 1.8e-59 K DeoR C terminal sensor domain
MDIOCMKF_00307 1.1e-79 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MDIOCMKF_00308 2.4e-57 yxeH S hydrolase
MDIOCMKF_00309 1.5e-143 pnuC H nicotinamide mononucleotide transporter
MDIOCMKF_00310 0.0 M domain protein
MDIOCMKF_00311 9.3e-104 GM domain, Protein
MDIOCMKF_00312 7.5e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDIOCMKF_00313 6.1e-43 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_00314 6.2e-126 S PAS domain
MDIOCMKF_00315 4.6e-181 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDIOCMKF_00316 9.1e-206 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
MDIOCMKF_00317 1.1e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDIOCMKF_00318 3e-58
MDIOCMKF_00319 0.0 uvrA3 L excinuclease ABC, A subunit
MDIOCMKF_00320 0.0 oppA E ABC transporter substrate-binding protein
MDIOCMKF_00321 3.6e-101 S PFAM Archaeal ATPase
MDIOCMKF_00322 4.7e-155 EG EamA-like transporter family
MDIOCMKF_00323 7.7e-102 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDIOCMKF_00324 1.9e-145 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDIOCMKF_00325 2e-49 bglP 2.7.1.211 G phosphotransferase system
MDIOCMKF_00326 4e-282 bglP 2.7.1.211 G phosphotransferase system
MDIOCMKF_00327 1.6e-132 licT K CAT RNA binding domain
MDIOCMKF_00328 0.0 fhaB M Rib/alpha-like repeat
MDIOCMKF_00329 3.7e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDIOCMKF_00330 5.3e-161 coaA 2.7.1.33 F Pantothenic acid kinase
MDIOCMKF_00331 3.4e-103 E GDSL-like Lipase/Acylhydrolase
MDIOCMKF_00332 9.5e-242 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDIOCMKF_00333 3.8e-82 rarA L MgsA AAA+ ATPase C terminal
MDIOCMKF_00334 2.3e-122 K Helix-turn-helix domain, rpiR family
MDIOCMKF_00335 1.8e-130 yvpB S Peptidase_C39 like family
MDIOCMKF_00336 5.1e-146 S cog cog1373
MDIOCMKF_00337 0.0 helD 3.6.4.12 L DNA helicase
MDIOCMKF_00338 6.2e-80 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MDIOCMKF_00340 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
MDIOCMKF_00341 8.3e-68
MDIOCMKF_00342 0.0 uup S ABC transporter, ATP-binding protein
MDIOCMKF_00343 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDIOCMKF_00344 1.3e-99 yvdD 3.2.2.10 S Belongs to the LOG family
MDIOCMKF_00345 1e-78 XK27_02470 K LytTr DNA-binding domain
MDIOCMKF_00346 1.3e-123 liaI S membrane
MDIOCMKF_00348 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDIOCMKF_00349 8.2e-296 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDIOCMKF_00350 1.7e-62 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
MDIOCMKF_00351 0.0 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
MDIOCMKF_00352 0.0 nisT V ABC transporter
MDIOCMKF_00353 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDIOCMKF_00354 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDIOCMKF_00355 1.6e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDIOCMKF_00356 1.4e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDIOCMKF_00357 4.5e-31 yajC U Preprotein translocase
MDIOCMKF_00358 1.1e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDIOCMKF_00359 1.4e-209 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDIOCMKF_00360 6.6e-184 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MDIOCMKF_00361 1.5e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDIOCMKF_00362 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDIOCMKF_00363 2.6e-42 yrzL S Belongs to the UPF0297 family
MDIOCMKF_00364 1.4e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDIOCMKF_00365 1.8e-50 yrzB S Belongs to the UPF0473 family
MDIOCMKF_00366 1.6e-91 cvpA S Colicin V production protein
MDIOCMKF_00367 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDIOCMKF_00368 6.6e-53 trxA O Belongs to the thioredoxin family
MDIOCMKF_00369 2.4e-68 yslB S Protein of unknown function (DUF2507)
MDIOCMKF_00370 6.5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MDIOCMKF_00371 2.2e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDIOCMKF_00372 5.9e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDIOCMKF_00373 2e-158 ykuT M mechanosensitive ion channel
MDIOCMKF_00375 4e-51
MDIOCMKF_00376 5.9e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MDIOCMKF_00377 3.6e-177 ccpA K catabolite control protein A
MDIOCMKF_00378 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
MDIOCMKF_00379 1.2e-274 pepV 3.5.1.18 E dipeptidase PepV
MDIOCMKF_00380 8e-268 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MDIOCMKF_00381 2e-55
MDIOCMKF_00382 3.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MDIOCMKF_00383 9.1e-98 yutD S Protein of unknown function (DUF1027)
MDIOCMKF_00384 3.6e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDIOCMKF_00385 8.6e-105 S Protein of unknown function (DUF1461)
MDIOCMKF_00386 2.7e-117 dedA S SNARE-like domain protein
MDIOCMKF_00387 4.8e-179 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MDIOCMKF_00388 6e-61 yugI 5.3.1.9 J general stress protein
MDIOCMKF_00389 5.9e-94 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
MDIOCMKF_00390 1.6e-127 terC P Integral membrane protein TerC family
MDIOCMKF_00391 1.5e-64 yeaO S Protein of unknown function, DUF488
MDIOCMKF_00392 1.2e-106 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MDIOCMKF_00393 9.7e-281 glnP P ABC transporter permease
MDIOCMKF_00394 9.6e-138 glnQ E ABC transporter, ATP-binding protein
MDIOCMKF_00395 3.7e-162 L HNH nucleases
MDIOCMKF_00396 4.5e-120 yfbR S HD containing hydrolase-like enzyme
MDIOCMKF_00397 5.4e-214 G Glycosyl hydrolases family 8
MDIOCMKF_00398 3.7e-246 ydaM M Glycosyl transferase
MDIOCMKF_00400 1.7e-154
MDIOCMKF_00401 1.7e-16
MDIOCMKF_00402 1.3e-69 S Iron-sulphur cluster biosynthesis
MDIOCMKF_00403 5.4e-182 ybiR P Citrate transporter
MDIOCMKF_00404 9.9e-92 lemA S LemA family
MDIOCMKF_00405 3.8e-146 htpX O Belongs to the peptidase M48B family
MDIOCMKF_00406 1.5e-169 K helix_turn_helix, arabinose operon control protein
MDIOCMKF_00407 4.8e-94 S ABC-type cobalt transport system, permease component
MDIOCMKF_00408 4.3e-250 cbiO1 S ABC transporter, ATP-binding protein
MDIOCMKF_00409 2.1e-109 P Cobalt transport protein
MDIOCMKF_00410 9.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDIOCMKF_00411 3.5e-182 htrA 3.4.21.107 O serine protease
MDIOCMKF_00412 3.3e-149 vicX 3.1.26.11 S domain protein
MDIOCMKF_00413 1.4e-142 yycI S YycH protein
MDIOCMKF_00414 3.5e-252 yycH S YycH protein
MDIOCMKF_00415 0.0 vicK 2.7.13.3 T Histidine kinase
MDIOCMKF_00416 1.2e-129 K response regulator
MDIOCMKF_00419 4.3e-149 arbV 2.3.1.51 I Acyl-transferase
MDIOCMKF_00420 3.2e-155 arbx M Glycosyl transferase family 8
MDIOCMKF_00421 9.4e-183 arbY M Glycosyl transferase family 8
MDIOCMKF_00422 2.5e-183 arbY M Glycosyl transferase family 8
MDIOCMKF_00423 3.3e-163 arbZ I Phosphate acyltransferases
MDIOCMKF_00424 4.6e-236 yhjX_2 P Major Facilitator Superfamily
MDIOCMKF_00425 1.7e-249 yhjX_2 P Major Facilitator Superfamily
MDIOCMKF_00426 1.2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MDIOCMKF_00427 3.2e-88 S Peptidase propeptide and YPEB domain
MDIOCMKF_00428 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MDIOCMKF_00429 2.5e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDIOCMKF_00430 4.4e-242 brnQ U Component of the transport system for branched-chain amino acids
MDIOCMKF_00431 0.0 1.3.5.4 C FAD binding domain
MDIOCMKF_00432 2.4e-164 K LysR substrate binding domain
MDIOCMKF_00433 1.6e-266 E amino acid
MDIOCMKF_00434 0.0 3.1.31.1 M domain protein
MDIOCMKF_00435 0.0 infB UW LPXTG-motif cell wall anchor domain protein
MDIOCMKF_00436 1.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDIOCMKF_00437 7.8e-216 iscS2 2.8.1.7 E Aminotransferase class V
MDIOCMKF_00438 5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDIOCMKF_00439 7.8e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDIOCMKF_00440 4.2e-211 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MDIOCMKF_00441 0.0 3.6.3.8 P P-type ATPase
MDIOCMKF_00442 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDIOCMKF_00443 2.8e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MDIOCMKF_00444 9.2e-124 S Haloacid dehalogenase-like hydrolase
MDIOCMKF_00445 1.4e-110 radC L DNA repair protein
MDIOCMKF_00446 6.5e-166 mreB D cell shape determining protein MreB
MDIOCMKF_00447 1e-143 mreC M Involved in formation and maintenance of cell shape
MDIOCMKF_00448 5.4e-95 mreD
MDIOCMKF_00449 3.6e-13 S Protein of unknown function (DUF4044)
MDIOCMKF_00450 6.1e-52 S Protein of unknown function (DUF3397)
MDIOCMKF_00451 4.1e-77 mraZ K Belongs to the MraZ family
MDIOCMKF_00452 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDIOCMKF_00453 6.3e-55 ftsL D Cell division protein FtsL
MDIOCMKF_00454 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MDIOCMKF_00455 1.6e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDIOCMKF_00456 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDIOCMKF_00457 3.6e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDIOCMKF_00458 6.3e-154 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDIOCMKF_00459 2.7e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDIOCMKF_00460 4.1e-232 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDIOCMKF_00461 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDIOCMKF_00462 2e-27 yggT S YGGT family
MDIOCMKF_00463 4.8e-148 ylmH S S4 domain protein
MDIOCMKF_00464 2.4e-112 gpsB D DivIVA domain protein
MDIOCMKF_00465 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDIOCMKF_00466 2e-32 cspA K 'Cold-shock' DNA-binding domain
MDIOCMKF_00467 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MDIOCMKF_00469 5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDIOCMKF_00470 3.3e-214 iscS 2.8.1.7 E Aminotransferase class V
MDIOCMKF_00471 1.6e-57 XK27_04120 S Putative amino acid metabolism
MDIOCMKF_00472 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDIOCMKF_00473 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MDIOCMKF_00474 5.1e-116 S Repeat protein
MDIOCMKF_00475 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDIOCMKF_00476 9.9e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MDIOCMKF_00477 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDIOCMKF_00478 3e-34 ykzG S Belongs to the UPF0356 family
MDIOCMKF_00479 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDIOCMKF_00480 0.0 typA T GTP-binding protein TypA
MDIOCMKF_00481 2.5e-209 ftsW D Belongs to the SEDS family
MDIOCMKF_00482 6.1e-52 ylbG S UPF0298 protein
MDIOCMKF_00483 1.6e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MDIOCMKF_00484 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDIOCMKF_00485 2.5e-186 ylbL T Belongs to the peptidase S16 family
MDIOCMKF_00486 2.4e-79 comEA L Competence protein ComEA
MDIOCMKF_00487 2e-42 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
MDIOCMKF_00488 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
MDIOCMKF_00489 2.2e-139
MDIOCMKF_00490 2e-105 speG J Acetyltransferase (GNAT) domain
MDIOCMKF_00491 1e-09 K sequence-specific DNA binding
MDIOCMKF_00492 1.3e-54 K sequence-specific DNA binding
MDIOCMKF_00493 1.2e-141 S Protein of unknown function (DUF975)
MDIOCMKF_00494 1.6e-128 qmcA O prohibitin homologues
MDIOCMKF_00495 2.6e-149 ropB K Helix-turn-helix domain
MDIOCMKF_00496 2e-294 V ABC-type multidrug transport system, ATPase and permease components
MDIOCMKF_00497 1.7e-84 C nitroreductase
MDIOCMKF_00498 5e-282 V ABC transporter transmembrane region
MDIOCMKF_00499 1.1e-48
MDIOCMKF_00500 4.5e-36 K Acetyltransferase (GNAT) domain
MDIOCMKF_00501 1.2e-22 K Acetyltransferase (GNAT) domain
MDIOCMKF_00502 1.9e-152 S Protein of unknown function (DUF2785)
MDIOCMKF_00503 1.6e-48 S MazG-like family
MDIOCMKF_00504 2.1e-63
MDIOCMKF_00505 1.4e-135
MDIOCMKF_00507 6e-143 3.1.3.48 T Tyrosine phosphatase family
MDIOCMKF_00508 3.6e-151 S Fic/DOC family
MDIOCMKF_00509 2.7e-51 S endonuclease activity
MDIOCMKF_00510 2.5e-43
MDIOCMKF_00511 1.4e-98 rimL J Acetyltransferase (GNAT) domain
MDIOCMKF_00512 2.6e-88 2.3.1.57 K Acetyltransferase (GNAT) family
MDIOCMKF_00513 1.6e-137 2.4.2.3 F Phosphorylase superfamily
MDIOCMKF_00514 1.8e-83 6.3.3.2 S ASCH
MDIOCMKF_00515 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDIOCMKF_00516 6.1e-160 rbsU U ribose uptake protein RbsU
MDIOCMKF_00517 1.4e-158 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
MDIOCMKF_00518 1.1e-289 V ABC-type multidrug transport system, ATPase and permease components
MDIOCMKF_00519 1.6e-272 V ABC-type multidrug transport system, ATPase and permease components
MDIOCMKF_00520 5.2e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDIOCMKF_00521 4.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MDIOCMKF_00522 3e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MDIOCMKF_00523 4.4e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
MDIOCMKF_00524 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MDIOCMKF_00525 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MDIOCMKF_00526 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MDIOCMKF_00527 2.1e-77 ypmB S Protein conserved in bacteria
MDIOCMKF_00528 2.9e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MDIOCMKF_00529 6.7e-116 dnaD L DnaD domain protein
MDIOCMKF_00530 1.2e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDIOCMKF_00531 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MDIOCMKF_00532 1.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDIOCMKF_00533 4.2e-106 ypsA S Belongs to the UPF0398 family
MDIOCMKF_00534 7.3e-266 yxbA 6.3.1.12 S ATP-grasp enzyme
MDIOCMKF_00535 0.0 asnB 6.3.5.4 E Asparagine synthase
MDIOCMKF_00536 3.1e-275 S Calcineurin-like phosphoesterase
MDIOCMKF_00537 7.3e-83
MDIOCMKF_00538 5.4e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MDIOCMKF_00539 1.6e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MDIOCMKF_00540 1.6e-140 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MDIOCMKF_00541 9.8e-169 phnD P Phosphonate ABC transporter
MDIOCMKF_00543 3.8e-87 uspA T universal stress protein
MDIOCMKF_00544 5.7e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
MDIOCMKF_00545 1.5e-132 XK27_08440 K UTRA domain
MDIOCMKF_00546 4.9e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDIOCMKF_00547 3.3e-88 ntd 2.4.2.6 F Nucleoside
MDIOCMKF_00548 1.4e-189
MDIOCMKF_00549 2.3e-207 S zinc-ribbon domain
MDIOCMKF_00550 1.3e-18 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_00551 9.3e-68 2.7.1.191 G PTS system fructose IIA component
MDIOCMKF_00552 5.5e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
MDIOCMKF_00553 1.9e-140 XK27_08455 G PTS system sorbose-specific iic component
MDIOCMKF_00554 8.7e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
MDIOCMKF_00555 1.8e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDIOCMKF_00556 2.4e-217 agaS G SIS domain
MDIOCMKF_00557 5.3e-130 XK27_08435 K UTRA
MDIOCMKF_00558 0.0 G Belongs to the glycosyl hydrolase 31 family
MDIOCMKF_00559 2.2e-156 I alpha/beta hydrolase fold
MDIOCMKF_00560 4.9e-118 yibF S overlaps another CDS with the same product name
MDIOCMKF_00561 1.4e-187 yibE S overlaps another CDS with the same product name
MDIOCMKF_00562 1.3e-141 yjcE P Sodium proton antiporter
MDIOCMKF_00563 6.5e-117 yjcE P Sodium proton antiporter
MDIOCMKF_00564 3.3e-95
MDIOCMKF_00565 2.8e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MDIOCMKF_00566 7.2e-286 S Cysteine-rich secretory protein family
MDIOCMKF_00567 1.1e-139
MDIOCMKF_00568 6.4e-114 luxT K Bacterial regulatory proteins, tetR family
MDIOCMKF_00569 2.8e-241 cycA E Amino acid permease
MDIOCMKF_00570 4.2e-220 S CAAX protease self-immunity
MDIOCMKF_00571 4.5e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDIOCMKF_00572 1.4e-62
MDIOCMKF_00573 6.9e-124 S Alpha/beta hydrolase family
MDIOCMKF_00574 2.2e-143 2.4.1.293 GT2 M Glycosyltransferase like family 2
MDIOCMKF_00575 2.4e-162 ypuA S Protein of unknown function (DUF1002)
MDIOCMKF_00576 6.2e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDIOCMKF_00577 6.3e-176 S Alpha/beta hydrolase of unknown function (DUF915)
MDIOCMKF_00578 5.6e-124 yugP S Putative neutral zinc metallopeptidase
MDIOCMKF_00579 1.9e-272 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDIOCMKF_00580 6.7e-81
MDIOCMKF_00581 6.9e-89 cobB K SIR2 family
MDIOCMKF_00582 2.1e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MDIOCMKF_00583 1.5e-35 relB L RelB antitoxin
MDIOCMKF_00585 5.3e-228 L Transposase
MDIOCMKF_00586 8.9e-47 higA K Helix-turn-helix XRE-family like proteins
MDIOCMKF_00587 4.5e-48 S RelE-like toxin of type II toxin-antitoxin system HigB
MDIOCMKF_00588 1.4e-19
MDIOCMKF_00589 1.1e-192 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDIOCMKF_00590 9.3e-74 nrdI F NrdI Flavodoxin like
MDIOCMKF_00591 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDIOCMKF_00592 4.1e-121 L Transposase and inactivated derivatives, IS30 family
MDIOCMKF_00593 8.6e-23 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDIOCMKF_00594 8.2e-204 gatC G PTS system sugar-specific permease component
MDIOCMKF_00595 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MDIOCMKF_00596 1e-56 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDIOCMKF_00597 5.6e-119 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MDIOCMKF_00599 5.9e-77 S Fic/DOC family
MDIOCMKF_00600 2.4e-75 L Resolvase, N terminal domain
MDIOCMKF_00601 2.3e-30 K Antidote-toxin recognition MazE, bacterial antitoxin
MDIOCMKF_00602 2e-29
MDIOCMKF_00604 1.8e-66 V N-6 DNA Methylase
MDIOCMKF_00605 1.6e-24 S Type I restriction modification DNA specificity domain
MDIOCMKF_00606 7.4e-185 L N-6 DNA Methylase
MDIOCMKF_00608 2.4e-31 N PFAM Uncharacterised protein family UPF0150
MDIOCMKF_00610 1.3e-09 S Protein of unknown function (DUF669)
MDIOCMKF_00611 1.2e-118 res L Helicase C-terminal domain protein
MDIOCMKF_00617 9.5e-41 lemA S LemA family
MDIOCMKF_00619 1.9e-14 S TPM domain
MDIOCMKF_00620 3.3e-21
MDIOCMKF_00625 2e-14 S Domain of Unknown Function with PDB structure (DUF3850)
MDIOCMKF_00627 3.6e-45 ybl78 L DnaD domain protein
MDIOCMKF_00629 1e-12 2.6.1.2, 2.6.1.66 K sequence-specific DNA binding
MDIOCMKF_00631 2.5e-79
MDIOCMKF_00632 6.7e-25 S HicB_like antitoxin of bacterial toxin-antitoxin system
MDIOCMKF_00633 1.3e-30
MDIOCMKF_00634 1.2e-54 doc S Fic/DOC family
MDIOCMKF_00635 1.4e-43 gepA S Protein of unknown function (DUF4065)
MDIOCMKF_00636 8.1e-27
MDIOCMKF_00637 1.8e-223 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
MDIOCMKF_00638 5.2e-57 gepA K Protein of unknown function (DUF4065)
MDIOCMKF_00639 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDIOCMKF_00640 7.7e-43
MDIOCMKF_00641 3.9e-256 pepC 3.4.22.40 E aminopeptidase
MDIOCMKF_00642 8.8e-124 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDIOCMKF_00643 3.7e-262 pepC 3.4.22.40 E aminopeptidase
MDIOCMKF_00645 6.3e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDIOCMKF_00646 0.0 XK27_08315 M Sulfatase
MDIOCMKF_00647 1.1e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDIOCMKF_00648 5.6e-195 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDIOCMKF_00649 9e-172 yqhA G Aldose 1-epimerase
MDIOCMKF_00650 7.8e-152 glcU U sugar transport
MDIOCMKF_00651 9.3e-119
MDIOCMKF_00652 8e-179 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MDIOCMKF_00653 3.2e-69 2.4.1.83 GT2 S GtrA-like protein
MDIOCMKF_00654 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDIOCMKF_00655 3.8e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDIOCMKF_00656 1.4e-74 S PAS domain
MDIOCMKF_00657 2.9e-148
MDIOCMKF_00658 4e-131
MDIOCMKF_00659 1.7e-179 S Oxidoreductase family, NAD-binding Rossmann fold
MDIOCMKF_00660 0.0 yjbQ P TrkA C-terminal domain protein
MDIOCMKF_00661 1.1e-144 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
MDIOCMKF_00662 1.5e-250 lysA2 M Glycosyl hydrolases family 25
MDIOCMKF_00663 8.6e-265 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDIOCMKF_00664 1.4e-34 S Protein of unknown function (DUF2922)
MDIOCMKF_00665 1.7e-28
MDIOCMKF_00666 2e-109
MDIOCMKF_00667 1.7e-72
MDIOCMKF_00668 0.0 kup P Transport of potassium into the cell
MDIOCMKF_00669 0.0 kup P Transport of potassium into the cell
MDIOCMKF_00670 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MDIOCMKF_00671 9.7e-245 yfnA E Amino Acid
MDIOCMKF_00672 0.0 clpE2 O AAA domain (Cdc48 subfamily)
MDIOCMKF_00673 1.1e-156 S Alpha/beta hydrolase of unknown function (DUF915)
MDIOCMKF_00674 2.6e-239 pts13C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDIOCMKF_00675 2.1e-38
MDIOCMKF_00676 2e-214 lmrP E Major Facilitator Superfamily
MDIOCMKF_00677 1.7e-173 pbpX2 V Beta-lactamase
MDIOCMKF_00678 9.3e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDIOCMKF_00679 3.9e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDIOCMKF_00680 1.4e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
MDIOCMKF_00681 4.3e-283 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDIOCMKF_00683 4.4e-43
MDIOCMKF_00684 1.8e-196 ywhK S Membrane
MDIOCMKF_00686 7.1e-56
MDIOCMKF_00688 4.6e-31
MDIOCMKF_00689 5.9e-40
MDIOCMKF_00690 5.9e-19
MDIOCMKF_00691 1.9e-83 ykuL S (CBS) domain
MDIOCMKF_00692 0.0 cadA P P-type ATPase
MDIOCMKF_00693 3.5e-200 napA P Sodium/hydrogen exchanger family
MDIOCMKF_00695 2.7e-280 V ABC transporter transmembrane region
MDIOCMKF_00696 8.5e-159 mutR K Helix-turn-helix XRE-family like proteins
MDIOCMKF_00697 6.2e-28
MDIOCMKF_00698 4.1e-31
MDIOCMKF_00699 2.1e-30
MDIOCMKF_00700 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDIOCMKF_00701 3.8e-157 S Protein of unknown function (DUF979)
MDIOCMKF_00702 2.3e-114 S Protein of unknown function (DUF969)
MDIOCMKF_00703 2.7e-234 G PTS system sugar-specific permease component
MDIOCMKF_00704 4.5e-269 G PTS system Galactitol-specific IIC component
MDIOCMKF_00705 2.2e-93 S Protein of unknown function (DUF1440)
MDIOCMKF_00706 6.5e-103 S CAAX protease self-immunity
MDIOCMKF_00707 1.5e-195 S DUF218 domain
MDIOCMKF_00708 0.0 macB_3 V ABC transporter, ATP-binding protein
MDIOCMKF_00709 1.9e-269 cydA 1.10.3.14 C ubiquinol oxidase
MDIOCMKF_00710 2.2e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MDIOCMKF_00711 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MDIOCMKF_00712 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MDIOCMKF_00713 1.1e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MDIOCMKF_00714 1.2e-166 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
MDIOCMKF_00715 7.1e-195 tcsA S ABC transporter substrate-binding protein PnrA-like
MDIOCMKF_00716 4.8e-173 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
MDIOCMKF_00717 5.3e-177 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
MDIOCMKF_00718 2e-99 G PTS system sorbose-specific iic component
MDIOCMKF_00719 1e-119 G PTS system mannose/fructose/sorbose family IID component
MDIOCMKF_00720 1.3e-52 2.7.1.191 G PTS system sorbose subfamily IIB component
MDIOCMKF_00721 3.2e-88 blaA6 V Beta-lactamase
MDIOCMKF_00722 5.7e-189 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MDIOCMKF_00723 4.1e-130 3.5.2.6 V Beta-lactamase enzyme family
MDIOCMKF_00724 2e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDIOCMKF_00725 1.2e-132 S membrane transporter protein
MDIOCMKF_00726 2.2e-27 G PTS system fructose IIA component
MDIOCMKF_00727 1.3e-121 G PTS system mannose/fructose/sorbose family IID component
MDIOCMKF_00728 1.7e-92 agaC G PTS system sorbose-specific iic component
MDIOCMKF_00729 4.6e-150 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
MDIOCMKF_00731 3.6e-19 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_00732 9.8e-160 yeaE S Aldo/keto reductase family
MDIOCMKF_00733 1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDIOCMKF_00734 7.7e-120 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MDIOCMKF_00735 3.7e-125 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MDIOCMKF_00736 6e-238 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MDIOCMKF_00737 3e-232 pbuG S permease
MDIOCMKF_00739 4.1e-109 K helix_turn_helix, mercury resistance
MDIOCMKF_00740 2.3e-232 pbuG S permease
MDIOCMKF_00741 3.4e-46 I bis(5'-adenosyl)-triphosphatase activity
MDIOCMKF_00742 1.1e-226 pbuG S permease
MDIOCMKF_00743 3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDIOCMKF_00744 4.1e-90
MDIOCMKF_00745 5.5e-90
MDIOCMKF_00746 1.4e-77 atkY K Penicillinase repressor
MDIOCMKF_00747 6.3e-66 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MDIOCMKF_00748 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MDIOCMKF_00749 0.0 copA 3.6.3.54 P P-type ATPase
MDIOCMKF_00750 4.4e-155 ropB K Helix-turn-helix XRE-family like proteins
MDIOCMKF_00751 0.0 pepO 3.4.24.71 O Peptidase family M13
MDIOCMKF_00752 4.1e-286 E Amino acid permease
MDIOCMKF_00753 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MDIOCMKF_00754 1e-248 ynbB 4.4.1.1 P aluminum resistance
MDIOCMKF_00755 2.3e-75 K Acetyltransferase (GNAT) domain
MDIOCMKF_00756 2.3e-232 EGP Sugar (and other) transporter
MDIOCMKF_00757 6.5e-69 S Iron-sulphur cluster biosynthesis
MDIOCMKF_00758 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDIOCMKF_00759 1.5e-115 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MDIOCMKF_00760 1.3e-71
MDIOCMKF_00761 1.7e-151 ropB K Transcriptional regulator
MDIOCMKF_00762 1.2e-201 EGP Major facilitator Superfamily
MDIOCMKF_00763 1e-276 clcA P chloride
MDIOCMKF_00764 6.6e-270 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDIOCMKF_00765 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MDIOCMKF_00766 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDIOCMKF_00767 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDIOCMKF_00768 3.7e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDIOCMKF_00769 6.6e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDIOCMKF_00770 9.4e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MDIOCMKF_00771 7e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDIOCMKF_00772 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDIOCMKF_00773 3.9e-19 yaaA S S4 domain
MDIOCMKF_00774 4.5e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDIOCMKF_00775 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDIOCMKF_00776 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDIOCMKF_00777 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
MDIOCMKF_00778 1.7e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDIOCMKF_00779 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDIOCMKF_00780 1.6e-155 corA P CorA-like Mg2+ transporter protein
MDIOCMKF_00781 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MDIOCMKF_00782 4.8e-76 rplI J Binds to the 23S rRNA
MDIOCMKF_00783 1.1e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MDIOCMKF_00784 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MDIOCMKF_00785 8.2e-218 I Protein of unknown function (DUF2974)
MDIOCMKF_00786 0.0
MDIOCMKF_00787 3.9e-117 yhiD S MgtC family
MDIOCMKF_00789 7.9e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MDIOCMKF_00790 1.2e-20 WQ51_00220 K Helix-turn-helix XRE-family like proteins
MDIOCMKF_00791 1.3e-85 S Protein of unknown function (DUF3278)
MDIOCMKF_00792 4.9e-201 S Aldo keto reductase
MDIOCMKF_00794 4.6e-224 S Sterol carrier protein domain
MDIOCMKF_00795 3e-116 ywnB S NAD(P)H-binding
MDIOCMKF_00796 7.2e-68
MDIOCMKF_00797 1.6e-64 S Domain of unknown function DUF1828
MDIOCMKF_00798 7.4e-88 S Rib/alpha-like repeat
MDIOCMKF_00799 2.9e-246 yagE E amino acid
MDIOCMKF_00800 5.1e-116 GM NmrA-like family
MDIOCMKF_00801 1.9e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
MDIOCMKF_00802 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
MDIOCMKF_00803 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDIOCMKF_00804 3.9e-240 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDIOCMKF_00805 0.0 oatA I Acyltransferase
MDIOCMKF_00806 1.4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDIOCMKF_00807 9.3e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MDIOCMKF_00808 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
MDIOCMKF_00809 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MDIOCMKF_00810 8.1e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MDIOCMKF_00811 2.1e-28 S Protein of unknown function (DUF2929)
MDIOCMKF_00812 0.0 dnaE 2.7.7.7 L DNA polymerase
MDIOCMKF_00814 2.7e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDIOCMKF_00815 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MDIOCMKF_00816 1.5e-166 cvfB S S1 domain
MDIOCMKF_00817 2.5e-169 xerD D recombinase XerD
MDIOCMKF_00818 3.1e-62 ribT K acetyltransferase
MDIOCMKF_00819 1.1e-135 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDIOCMKF_00820 2.9e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDIOCMKF_00821 1.8e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDIOCMKF_00822 1.9e-58 M Lysin motif
MDIOCMKF_00823 3.8e-97 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDIOCMKF_00824 1.4e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MDIOCMKF_00825 2.3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
MDIOCMKF_00826 9.4e-242 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MDIOCMKF_00827 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDIOCMKF_00828 1.1e-231 S Tetratricopeptide repeat protein
MDIOCMKF_00829 5.8e-35
MDIOCMKF_00830 1.5e-82 mutT 3.6.1.55 F NUDIX domain
MDIOCMKF_00831 3.1e-73
MDIOCMKF_00832 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MDIOCMKF_00833 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MDIOCMKF_00834 7.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDIOCMKF_00835 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDIOCMKF_00836 1.4e-65
MDIOCMKF_00837 2.3e-173 prmA J Ribosomal protein L11 methyltransferase
MDIOCMKF_00838 3e-87 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDIOCMKF_00839 0.0 S Bacterial membrane protein, YfhO
MDIOCMKF_00840 0.0 aha1 P E1-E2 ATPase
MDIOCMKF_00841 2.5e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
MDIOCMKF_00842 2.2e-257 yjjP S Putative threonine/serine exporter
MDIOCMKF_00843 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDIOCMKF_00844 2.1e-260 frdC 1.3.5.4 C FAD binding domain
MDIOCMKF_00845 3.8e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDIOCMKF_00846 2.8e-67 metI P ABC transporter permease
MDIOCMKF_00847 1.6e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDIOCMKF_00848 1.8e-156 metQ1 P Belongs to the nlpA lipoprotein family
MDIOCMKF_00849 7.6e-60 L nuclease
MDIOCMKF_00850 2.8e-146 F DNA/RNA non-specific endonuclease
MDIOCMKF_00851 2.7e-41 K Helix-turn-helix domain
MDIOCMKF_00852 3.4e-310 ybiT S ABC transporter, ATP-binding protein
MDIOCMKF_00853 3.7e-18 S Sugar efflux transporter for intercellular exchange
MDIOCMKF_00854 8.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDIOCMKF_00855 2.2e-102 3.6.1.27 I Acid phosphatase homologues
MDIOCMKF_00857 1.5e-76 2.3.1.128 K acetyltransferase
MDIOCMKF_00858 0.0 4.2.1.53 S Myosin-crossreactive antigen
MDIOCMKF_00859 7.6e-94 yxdD K Bacterial regulatory proteins, tetR family
MDIOCMKF_00860 4.5e-261 emrY EGP Major facilitator Superfamily
MDIOCMKF_00861 6.4e-255 emrY EGP Major facilitator Superfamily
MDIOCMKF_00862 1.4e-144 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MDIOCMKF_00863 2.3e-134 S CAAX amino terminal protease
MDIOCMKF_00864 6.9e-162 mleP3 S Membrane transport protein
MDIOCMKF_00865 2.1e-105 tag 3.2.2.20 L glycosylase
MDIOCMKF_00866 4.2e-194 S Bacteriocin helveticin-J
MDIOCMKF_00867 6.9e-83 yebR 1.8.4.14 T GAF domain-containing protein
MDIOCMKF_00868 3.9e-108 ylbE GM NAD(P)H-binding
MDIOCMKF_00869 2.7e-128 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
MDIOCMKF_00870 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDIOCMKF_00872 1.5e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MDIOCMKF_00873 9e-77 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
MDIOCMKF_00874 2.4e-50
MDIOCMKF_00875 7.2e-172 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MDIOCMKF_00876 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MDIOCMKF_00877 4.6e-91 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MDIOCMKF_00878 1.7e-63 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MDIOCMKF_00879 2.4e-124 M ErfK YbiS YcfS YnhG
MDIOCMKF_00880 4.3e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDIOCMKF_00881 8.8e-120
MDIOCMKF_00882 8.5e-215 I Protein of unknown function (DUF2974)
MDIOCMKF_00883 3.9e-301 ytgP S Polysaccharide biosynthesis protein
MDIOCMKF_00884 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDIOCMKF_00885 2.5e-80 3.6.1.27 I Acid phosphatase homologues
MDIOCMKF_00886 3.2e-259 qacA EGP Major facilitator Superfamily
MDIOCMKF_00887 4.8e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDIOCMKF_00893 2.6e-183 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MDIOCMKF_00894 1.1e-123 manY G PTS system
MDIOCMKF_00895 5.6e-172 manN G system, mannose fructose sorbose family IID component
MDIOCMKF_00896 1.8e-65 manO S Domain of unknown function (DUF956)
MDIOCMKF_00897 1.3e-249 yifK E Amino acid permease
MDIOCMKF_00898 9e-219 yifK E Amino acid permease
MDIOCMKF_00899 2.8e-134 puuD S peptidase C26
MDIOCMKF_00900 8.2e-236 steT_1 E amino acid
MDIOCMKF_00901 7.5e-193 S CAAX protease self-immunity
MDIOCMKF_00902 4e-192 asnA 6.3.1.1 F aspartate--ammonia ligase
MDIOCMKF_00903 1.2e-161 EG EamA-like transporter family
MDIOCMKF_00904 1.8e-251 yfnA E Amino Acid
MDIOCMKF_00905 8.6e-130 cobQ S glutamine amidotransferase
MDIOCMKF_00906 3.5e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MDIOCMKF_00907 9.1e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
MDIOCMKF_00908 1.2e-36 rpoN K Sigma-54 factor, core binding domain
MDIOCMKF_00909 8.3e-194 K Sigma-54 interaction domain
MDIOCMKF_00910 7.1e-21 2.7.1.191 G PTS system fructose IIA component
MDIOCMKF_00911 9.3e-33 2.7.1.191 G PTS system sorbose subfamily IIB component
MDIOCMKF_00912 1.7e-36 G PTS system sorbose-specific iic component
MDIOCMKF_00913 3.4e-59 G PTS system mannose/fructose/sorbose family IID component
MDIOCMKF_00914 4.4e-53 G polysaccharide catabolic process
MDIOCMKF_00915 1e-184 scrR K Transcriptional regulator, LacI family
MDIOCMKF_00916 2.3e-289 scrB 3.2.1.26 GH32 G invertase
MDIOCMKF_00917 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
MDIOCMKF_00918 3.4e-37
MDIOCMKF_00919 9.5e-119 ybhL S Belongs to the BI1 family
MDIOCMKF_00920 5.5e-104 4.1.1.45 S Amidohydrolase
MDIOCMKF_00921 1.5e-33 4.1.1.45 S Amidohydrolase
MDIOCMKF_00922 6.8e-245 yrvN L AAA C-terminal domain
MDIOCMKF_00923 7.3e-58 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MDIOCMKF_00924 1.3e-53 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MDIOCMKF_00925 2.5e-86 XK27_09675 K Acetyltransferase (GNAT) domain
MDIOCMKF_00926 7.9e-69 ogt 2.1.1.63 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
MDIOCMKF_00927 6.2e-76 K Transcriptional regulator
MDIOCMKF_00928 5.5e-50 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MDIOCMKF_00929 6.9e-80 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MDIOCMKF_00930 2.1e-96 K Acetyltransferase (GNAT) family
MDIOCMKF_00931 1.5e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MDIOCMKF_00932 1.4e-93 dps P Belongs to the Dps family
MDIOCMKF_00933 7.4e-35 copZ C Heavy-metal-associated domain
MDIOCMKF_00934 1.3e-21 cylB V ABC-2 type transporter
MDIOCMKF_00935 2.4e-68 S pyridoxamine 5-phosphate
MDIOCMKF_00936 3.1e-77 yobV1 K WYL domain
MDIOCMKF_00937 1.3e-70 yobV1 K WYL domain
MDIOCMKF_00938 4.1e-30 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MDIOCMKF_00939 2.3e-63 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDIOCMKF_00940 4.1e-264 npr 1.11.1.1 C NADH oxidase
MDIOCMKF_00941 1.9e-32 G Major facilitator Superfamily
MDIOCMKF_00942 4.9e-61 S Sulfite exporter TauE/SafE
MDIOCMKF_00943 1.2e-89 mdt(A) EGP Major facilitator Superfamily
MDIOCMKF_00944 7.2e-88 mdt(A) EGP Major facilitator Superfamily
MDIOCMKF_00945 2.1e-117 GM NAD(P)H-binding
MDIOCMKF_00946 1.7e-231 E Alpha/beta hydrolase of unknown function (DUF1100)
MDIOCMKF_00947 9.2e-101 K Transcriptional regulator C-terminal region
MDIOCMKF_00949 3.8e-156 C Aldo keto reductase
MDIOCMKF_00950 3.9e-126 lmrA 3.6.3.44 V ABC transporter
MDIOCMKF_00951 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MDIOCMKF_00952 1.7e-32 mta K helix_turn_helix, mercury resistance
MDIOCMKF_00953 4.4e-35 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
MDIOCMKF_00954 1.4e-189 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDIOCMKF_00955 1.2e-41 yphH S Cupin domain
MDIOCMKF_00956 0.0 UW LPXTG-motif cell wall anchor domain protein
MDIOCMKF_00957 0.0 UW LPXTG-motif cell wall anchor domain protein
MDIOCMKF_00958 4.2e-228 yttB EGP Major facilitator Superfamily
MDIOCMKF_00959 6.6e-187 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
MDIOCMKF_00960 4.1e-173 D nuclear chromosome segregation
MDIOCMKF_00961 2e-135 rpl K Helix-turn-helix domain, rpiR family
MDIOCMKF_00962 1.1e-164 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
MDIOCMKF_00963 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDIOCMKF_00964 0.0 pepO 3.4.24.71 O Peptidase family M13
MDIOCMKF_00965 0.0 S Bacterial membrane protein, YfhO
MDIOCMKF_00966 9.3e-102 ltrA S Bacterial low temperature requirement A protein (LtrA)
MDIOCMKF_00967 2.9e-148 dkg S reductase
MDIOCMKF_00968 2.2e-122 endA F DNA RNA non-specific endonuclease
MDIOCMKF_00969 4.3e-280 pipD E Dipeptidase
MDIOCMKF_00970 7.9e-202 malK P ATPases associated with a variety of cellular activities
MDIOCMKF_00971 9.5e-158 gtsB P ABC-type sugar transport systems, permease components
MDIOCMKF_00972 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
MDIOCMKF_00973 7.9e-257 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
MDIOCMKF_00974 3e-240 G Bacterial extracellular solute-binding protein
MDIOCMKF_00975 8.7e-52 ypaA S Protein of unknown function (DUF1304)
MDIOCMKF_00976 1.1e-77 yybA 2.3.1.57 K Transcriptional regulator
MDIOCMKF_00977 6e-97 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MDIOCMKF_00978 1.4e-80 yjcF S Acetyltransferase (GNAT) domain
MDIOCMKF_00979 5.4e-167 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
MDIOCMKF_00980 1.4e-167 3.5.2.6 V Beta-lactamase enzyme family
MDIOCMKF_00981 3.2e-98 yobS K Bacterial regulatory proteins, tetR family
MDIOCMKF_00982 5.6e-133 ydgH S MMPL family
MDIOCMKF_00983 1.3e-283 ydgH S MMPL family
MDIOCMKF_00984 3.4e-133 cof S haloacid dehalogenase-like hydrolase
MDIOCMKF_00985 2.1e-123 S SNARE associated Golgi protein
MDIOCMKF_00986 5.1e-179
MDIOCMKF_00987 7.2e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MDIOCMKF_00988 5.8e-144 hipB K Helix-turn-helix
MDIOCMKF_00989 3.5e-151 I alpha/beta hydrolase fold
MDIOCMKF_00990 1.5e-106 yjbF S SNARE associated Golgi protein
MDIOCMKF_00991 1.1e-101 J Acetyltransferase (GNAT) domain
MDIOCMKF_00992 1.4e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDIOCMKF_00993 2.7e-296 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MDIOCMKF_00994 8.9e-192 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDIOCMKF_00995 4.2e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDIOCMKF_00996 0.0 S membrane
MDIOCMKF_00997 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDIOCMKF_00998 2.4e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDIOCMKF_00999 9.9e-61 yabR J S1 RNA binding domain
MDIOCMKF_01000 2.3e-60 divIC D Septum formation initiator
MDIOCMKF_01001 1.8e-34 yabO J S4 domain protein
MDIOCMKF_01002 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDIOCMKF_01003 3.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDIOCMKF_01004 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDIOCMKF_01005 2.4e-124 S (CBS) domain
MDIOCMKF_01006 1.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDIOCMKF_01007 5.9e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDIOCMKF_01008 7.7e-261 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDIOCMKF_01009 2.9e-262 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDIOCMKF_01010 8e-41 rpmE2 J Ribosomal protein L31
MDIOCMKF_01011 3.2e-284 ybeC E amino acid
MDIOCMKF_01012 6.9e-136 XK27_08845 S ABC transporter, ATP-binding protein
MDIOCMKF_01013 4.9e-141 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MDIOCMKF_01014 3e-187 ABC-SBP S ABC transporter
MDIOCMKF_01015 7.1e-132 S Protein of unknown function (DUF975)
MDIOCMKF_01016 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MDIOCMKF_01017 1.1e-153 yitS S EDD domain protein, DegV family
MDIOCMKF_01018 2.2e-19
MDIOCMKF_01019 0.0 tetP J elongation factor G
MDIOCMKF_01020 8.7e-63 P CorA-like Mg2+ transporter protein
MDIOCMKF_01021 1.2e-70 P CorA-like Mg2+ transporter protein
MDIOCMKF_01023 2.5e-40 S Transglycosylase associated protein
MDIOCMKF_01024 5.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
MDIOCMKF_01025 0.0 L Helicase C-terminal domain protein
MDIOCMKF_01026 2.2e-165 S Alpha beta hydrolase
MDIOCMKF_01027 1.8e-40
MDIOCMKF_01028 3.3e-165 K AI-2E family transporter
MDIOCMKF_01029 1e-251 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
MDIOCMKF_01030 6.2e-213 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDIOCMKF_01031 1.8e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
MDIOCMKF_01032 5.3e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDIOCMKF_01033 0.0 S domain, Protein
MDIOCMKF_01034 2.8e-113 S domain, Protein
MDIOCMKF_01035 4.9e-204 xerS L Belongs to the 'phage' integrase family
MDIOCMKF_01036 6.7e-167 K Transcriptional regulator
MDIOCMKF_01037 3.7e-151
MDIOCMKF_01038 3.8e-162 degV S EDD domain protein, DegV family
MDIOCMKF_01039 3.8e-64
MDIOCMKF_01040 0.0 FbpA K Fibronectin-binding protein
MDIOCMKF_01041 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
MDIOCMKF_01042 2.8e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MDIOCMKF_01043 1.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDIOCMKF_01044 2.3e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDIOCMKF_01045 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MDIOCMKF_01046 9.9e-58
MDIOCMKF_01047 2.2e-173 degV S DegV family
MDIOCMKF_01048 2.3e-223 cpdA S Calcineurin-like phosphoesterase
MDIOCMKF_01049 2.4e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MDIOCMKF_01050 2e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDIOCMKF_01052 1.5e-24 S PFAM Archaeal ATPase
MDIOCMKF_01053 2.1e-241 pyrP F Permease
MDIOCMKF_01054 3.7e-137 lacR K DeoR C terminal sensor domain
MDIOCMKF_01055 9.4e-74 lacA 5.3.1.26 G Ribose/Galactose Isomerase
MDIOCMKF_01056 1.9e-106 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
MDIOCMKF_01057 1.6e-128 S Domain of unknown function (DUF4867)
MDIOCMKF_01058 7.2e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDIOCMKF_01059 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
MDIOCMKF_01060 1.4e-267 gatC G PTS system sugar-specific permease component
MDIOCMKF_01061 1.3e-38
MDIOCMKF_01062 1e-148 lacT K CAT RNA binding domain
MDIOCMKF_01063 8.7e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
MDIOCMKF_01064 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
MDIOCMKF_01065 4.8e-292 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
MDIOCMKF_01066 1e-201 S PFAM Archaeal ATPase
MDIOCMKF_01067 8.2e-165 K LysR family
MDIOCMKF_01068 0.0 1.3.5.4 C FMN_bind
MDIOCMKF_01069 8.3e-260 P Sodium:sulfate symporter transmembrane region
MDIOCMKF_01070 5.7e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
MDIOCMKF_01071 3.3e-112 3.6.1.27 I Acid phosphatase homologues
MDIOCMKF_01072 1.9e-217 mdtG EGP Major facilitator Superfamily
MDIOCMKF_01073 1.5e-32
MDIOCMKF_01074 6.1e-73 K helix_turn_helix multiple antibiotic resistance protein
MDIOCMKF_01075 5.8e-82
MDIOCMKF_01076 2.7e-210 pepA E M42 glutamyl aminopeptidase
MDIOCMKF_01078 5.9e-88 2.7.1.191 G PTS system sorbose subfamily IIB component
MDIOCMKF_01079 1.2e-103 G PTS system sorbose-specific iic component
MDIOCMKF_01080 3.4e-152 G PTS system mannose/fructose/sorbose family IID component
MDIOCMKF_01081 6.8e-72 2.7.1.191 G PTS system fructose IIA component
MDIOCMKF_01082 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MDIOCMKF_01083 8.2e-182 lacI3 K helix_turn _helix lactose operon repressor
MDIOCMKF_01084 4.4e-224 3.2.1.177 GH31 G Glycosyl hydrolases family 31
MDIOCMKF_01085 1e-169 3.2.1.177 GH31 G Glycosyl hydrolases family 31
MDIOCMKF_01086 1.6e-266 dtpT U amino acid peptide transporter
MDIOCMKF_01087 2.9e-208 naiP EGP Major facilitator Superfamily
MDIOCMKF_01088 3.8e-79 S Alpha beta hydrolase
MDIOCMKF_01089 1.8e-64 S Alpha beta hydrolase
MDIOCMKF_01090 4.6e-76 K Transcriptional regulator, MarR family
MDIOCMKF_01091 2.1e-52 XK27_09600 V ABC transporter, ATP-binding protein
MDIOCMKF_01092 7.1e-248 XK27_09600 V ABC transporter, ATP-binding protein
MDIOCMKF_01093 0.0 V ABC transporter transmembrane region
MDIOCMKF_01094 1.3e-148 glnH ET ABC transporter
MDIOCMKF_01095 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDIOCMKF_01096 9.1e-150 glnH ET ABC transporter
MDIOCMKF_01097 7.8e-109 gluC P ABC transporter permease
MDIOCMKF_01098 2e-107 glnP P ABC transporter permease
MDIOCMKF_01099 4.8e-151 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_01100 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MDIOCMKF_01101 1.1e-130 treR K UTRA
MDIOCMKF_01102 0.0 treB 2.7.1.211 G phosphotransferase system
MDIOCMKF_01103 8.3e-84 S Putative adhesin
MDIOCMKF_01104 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
MDIOCMKF_01105 1.9e-205 EGP Major facilitator superfamily
MDIOCMKF_01107 1.6e-35 S Enterocin A Immunity
MDIOCMKF_01108 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
MDIOCMKF_01109 5.7e-160 rssA S Phospholipase, patatin family
MDIOCMKF_01110 3.1e-257 glnPH2 P ABC transporter permease
MDIOCMKF_01111 1.7e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDIOCMKF_01112 6.2e-96 K Acetyltransferase (GNAT) domain
MDIOCMKF_01113 1.3e-159 pstS P Phosphate
MDIOCMKF_01114 2.1e-161 pstC P probably responsible for the translocation of the substrate across the membrane
MDIOCMKF_01115 8.3e-157 pstA P Phosphate transport system permease protein PstA
MDIOCMKF_01116 4.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDIOCMKF_01117 2.7e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDIOCMKF_01118 7.6e-118 phoU P Plays a role in the regulation of phosphate uptake
MDIOCMKF_01119 1.7e-282 S C4-dicarboxylate anaerobic carrier
MDIOCMKF_01120 5.8e-85 dps P Belongs to the Dps family
MDIOCMKF_01122 3.2e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDIOCMKF_01123 4.8e-128 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDIOCMKF_01124 4.1e-175 rihB 3.2.2.1 F Nucleoside
MDIOCMKF_01125 4e-133 gntR K UbiC transcription regulator-associated domain protein
MDIOCMKF_01126 2e-52 S Enterocin A Immunity
MDIOCMKF_01127 1.8e-116 glcR K DeoR C terminal sensor domain
MDIOCMKF_01128 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MDIOCMKF_01129 1.6e-120 C nitroreductase
MDIOCMKF_01130 1.1e-132
MDIOCMKF_01131 3.6e-252 yhdP S Transporter associated domain
MDIOCMKF_01132 2.8e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDIOCMKF_01133 5e-235 potE E amino acid
MDIOCMKF_01134 9.9e-137 M Glycosyl hydrolases family 25
MDIOCMKF_01135 4.1e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
MDIOCMKF_01136 2.1e-249 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDIOCMKF_01139 1.7e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDIOCMKF_01140 2e-86 gtcA S Teichoic acid glycosylation protein
MDIOCMKF_01141 4.2e-77 fld C Flavodoxin
MDIOCMKF_01142 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
MDIOCMKF_01143 1.6e-166 yihY S Belongs to the UPF0761 family
MDIOCMKF_01144 8.7e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MDIOCMKF_01145 8.8e-153 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_01146 4.4e-180 E ABC transporter, ATP-binding protein
MDIOCMKF_01147 1.6e-288 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDIOCMKF_01148 6.9e-66 O OsmC-like protein
MDIOCMKF_01149 8.3e-21 ltrA S Bacterial low temperature requirement A protein (LtrA)
MDIOCMKF_01150 1.9e-112 2.7.6.5 T Region found in RelA / SpoT proteins
MDIOCMKF_01151 5.3e-116 K response regulator
MDIOCMKF_01152 1.6e-233 sptS 2.7.13.3 T Histidine kinase
MDIOCMKF_01153 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MDIOCMKF_01154 1e-19
MDIOCMKF_01155 4.2e-50
MDIOCMKF_01156 0.0 pepN 3.4.11.2 E aminopeptidase
MDIOCMKF_01157 2.5e-141 S haloacid dehalogenase-like hydrolase
MDIOCMKF_01158 5.2e-122 S CAAX protease self-immunity
MDIOCMKF_01160 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDIOCMKF_01161 6.6e-72
MDIOCMKF_01162 2.1e-108 fic D Fic/DOC family
MDIOCMKF_01163 1.8e-225 I transferase activity, transferring acyl groups other than amino-acyl groups
MDIOCMKF_01164 3.5e-128 pnb C nitroreductase
MDIOCMKF_01165 7.1e-98 S Domain of unknown function (DUF4811)
MDIOCMKF_01166 1.8e-265 lmrB EGP Major facilitator Superfamily
MDIOCMKF_01167 1.2e-76 K MerR HTH family regulatory protein
MDIOCMKF_01168 0.0 oppA E ABC transporter substrate-binding protein
MDIOCMKF_01170 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDIOCMKF_01171 1e-81 yueI S Protein of unknown function (DUF1694)
MDIOCMKF_01172 7.4e-239 rarA L recombination factor protein RarA
MDIOCMKF_01174 5.2e-81 usp6 T universal stress protein
MDIOCMKF_01175 3.6e-224 rodA D Belongs to the SEDS family
MDIOCMKF_01176 1.3e-34 S Protein of unknown function (DUF2969)
MDIOCMKF_01177 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MDIOCMKF_01178 2.5e-15 S DNA-directed RNA polymerase subunit beta
MDIOCMKF_01179 2.2e-179 mbl D Cell shape determining protein MreB Mrl
MDIOCMKF_01180 2e-30 ywzB S Protein of unknown function (DUF1146)
MDIOCMKF_01181 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MDIOCMKF_01182 3.3e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDIOCMKF_01183 3.1e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDIOCMKF_01184 5.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDIOCMKF_01185 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDIOCMKF_01186 5.9e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDIOCMKF_01187 2.1e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDIOCMKF_01188 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
MDIOCMKF_01189 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDIOCMKF_01190 1.2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDIOCMKF_01191 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDIOCMKF_01192 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDIOCMKF_01193 5.5e-112 tdk 2.7.1.21 F thymidine kinase
MDIOCMKF_01194 1.2e-48 V ABC transporter transmembrane region
MDIOCMKF_01195 0.0 pacL 3.6.3.8 P P-type ATPase
MDIOCMKF_01196 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDIOCMKF_01197 2e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDIOCMKF_01198 0.0 tuaG GT2 M Glycosyltransferase like family 2
MDIOCMKF_01199 2.9e-204 csaB M Glycosyl transferases group 1
MDIOCMKF_01200 1.2e-140 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDIOCMKF_01201 1.5e-67 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MDIOCMKF_01202 9.5e-124 gntR1 K UTRA
MDIOCMKF_01203 9.3e-190
MDIOCMKF_01204 1.4e-52 P Rhodanese Homology Domain
MDIOCMKF_01207 1.2e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
MDIOCMKF_01208 1.8e-145 K SIS domain
MDIOCMKF_01209 0.0 lhr L DEAD DEAH box helicase
MDIOCMKF_01210 5.4e-253 P P-loop Domain of unknown function (DUF2791)
MDIOCMKF_01211 0.0 S TerB-C domain
MDIOCMKF_01212 1.3e-99 4.1.1.44 S decarboxylase
MDIOCMKF_01213 5.1e-72
MDIOCMKF_01214 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MDIOCMKF_01215 2.4e-232 cycA E Amino acid permease
MDIOCMKF_01218 1.8e-122 2.1.1.72, 3.1.21.3 V N-6 DNA Methylase
MDIOCMKF_01219 1.8e-26 2.1.1.72, 3.1.21.3 V restriction
MDIOCMKF_01220 3.6e-125 S Fic/DOC family
MDIOCMKF_01221 1.3e-07 K sequence-specific DNA binding
MDIOCMKF_01225 1.3e-95 D CobQ CobB MinD ParA nucleotide binding domain protein
MDIOCMKF_01227 5.4e-09 L Initiator Replication protein
MDIOCMKF_01228 3.9e-196 G Psort location CytoplasmicMembrane, score 10.00
MDIOCMKF_01229 2.2e-180 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDIOCMKF_01230 7.9e-75 K acetyltransferase
MDIOCMKF_01231 5.8e-49 psiE S Phosphate-starvation-inducible E
MDIOCMKF_01232 2.3e-133 S Putative ABC-transporter type IV
MDIOCMKF_01233 1.3e-110 M LysM domain protein
MDIOCMKF_01234 3.9e-93 M LysM domain protein
MDIOCMKF_01236 1.7e-59 yjgN S Bacterial protein of unknown function (DUF898)
MDIOCMKF_01237 1.8e-150 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MDIOCMKF_01238 2.9e-14 C Aldo/keto reductase family
MDIOCMKF_01239 1.1e-74 C Aldo/keto reductase family
MDIOCMKF_01240 3.3e-166 akr5f 1.1.1.346 S reductase
MDIOCMKF_01241 1.8e-124 magIII L Base excision DNA repair protein, HhH-GPD family
MDIOCMKF_01242 2.6e-109 lacA 2.3.1.79 S Transferase hexapeptide repeat
MDIOCMKF_01243 8.9e-116 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDIOCMKF_01244 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDIOCMKF_01245 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDIOCMKF_01246 3.3e-77 S Fic/DOC family
MDIOCMKF_01247 1.7e-103 S Uncharacterised protein family (UPF0236)
MDIOCMKF_01248 3.5e-13 fhaB M Rib/alpha-like repeat
MDIOCMKF_01249 4.2e-238 fhaB M Rib/alpha-like repeat
MDIOCMKF_01250 5e-60
MDIOCMKF_01262 4.2e-217 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
MDIOCMKF_01263 3.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
MDIOCMKF_01264 4.5e-183 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDIOCMKF_01265 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDIOCMKF_01266 2.2e-189 yhjX P Major Facilitator Superfamily
MDIOCMKF_01267 6.9e-83 I Carboxylesterase family
MDIOCMKF_01268 2.7e-63 I Carboxylesterase family
MDIOCMKF_01269 3.6e-165 rhaS6 K helix_turn_helix, arabinose operon control protein
MDIOCMKF_01270 4.7e-168 2.7.1.2 GK ROK family
MDIOCMKF_01271 4.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
MDIOCMKF_01272 7.8e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
MDIOCMKF_01273 7.6e-52 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
MDIOCMKF_01274 5.8e-155
MDIOCMKF_01275 2.8e-224 mdtG EGP Major facilitator Superfamily
MDIOCMKF_01276 1.9e-121 puuD S peptidase C26
MDIOCMKF_01277 1e-290 V ABC transporter transmembrane region
MDIOCMKF_01278 5.7e-86 ymdB S Macro domain protein
MDIOCMKF_01279 6.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MDIOCMKF_01280 4.8e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDIOCMKF_01281 4.1e-130 ymfC K UTRA
MDIOCMKF_01282 8.2e-254 3.5.1.18 E Peptidase family M20/M25/M40
MDIOCMKF_01283 1.3e-179 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
MDIOCMKF_01284 2.9e-93 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
MDIOCMKF_01285 4.6e-196 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDIOCMKF_01286 1.2e-117 cutC P Participates in the control of copper homeostasis
MDIOCMKF_01287 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MDIOCMKF_01288 1.4e-75 K UTRA
MDIOCMKF_01289 5.9e-12
MDIOCMKF_01290 1.5e-50 rmaI K Transcriptional regulator
MDIOCMKF_01291 2e-210 EGP Major facilitator Superfamily
MDIOCMKF_01292 5.7e-230 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MDIOCMKF_01293 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDIOCMKF_01294 1.3e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDIOCMKF_01295 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDIOCMKF_01296 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDIOCMKF_01297 2.3e-251 dnaB L Replication initiation and membrane attachment
MDIOCMKF_01298 2.7e-163 dnaI L Primosomal protein DnaI
MDIOCMKF_01299 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDIOCMKF_01300 1.4e-72 K LytTr DNA-binding domain
MDIOCMKF_01301 1.9e-74 S Protein of unknown function (DUF3021)
MDIOCMKF_01302 4.8e-171 V ABC transporter
MDIOCMKF_01303 1.3e-131 S domain protein
MDIOCMKF_01304 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDIOCMKF_01305 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MDIOCMKF_01306 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDIOCMKF_01307 9.8e-191 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MDIOCMKF_01308 3.5e-91 yqeG S HAD phosphatase, family IIIA
MDIOCMKF_01309 4.7e-210 yqeH S Ribosome biogenesis GTPase YqeH
MDIOCMKF_01310 4.4e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDIOCMKF_01311 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MDIOCMKF_01312 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDIOCMKF_01313 2.2e-218 ylbM S Belongs to the UPF0348 family
MDIOCMKF_01314 2.9e-96 yceD S Uncharacterized ACR, COG1399
MDIOCMKF_01315 1.1e-130 K response regulator
MDIOCMKF_01316 1.9e-281 arlS 2.7.13.3 T Histidine kinase
MDIOCMKF_01317 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDIOCMKF_01318 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MDIOCMKF_01319 9.6e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDIOCMKF_01320 7.3e-64 yodB K Transcriptional regulator, HxlR family
MDIOCMKF_01321 8.1e-204 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDIOCMKF_01322 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDIOCMKF_01323 2.9e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDIOCMKF_01324 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDIOCMKF_01325 0.0 S membrane
MDIOCMKF_01326 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MDIOCMKF_01327 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDIOCMKF_01328 5.6e-87 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDIOCMKF_01329 2e-118 gluP 3.4.21.105 S Rhomboid family
MDIOCMKF_01330 6e-35 yqgQ S Bacterial protein of unknown function (DUF910)
MDIOCMKF_01331 1.5e-57 yqhL P Rhodanese-like protein
MDIOCMKF_01332 1.1e-18 S Protein of unknown function (DUF3042)
MDIOCMKF_01333 9.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDIOCMKF_01334 1.1e-261 glnA 6.3.1.2 E glutamine synthetase
MDIOCMKF_01335 1.1e-204 EGP Major facilitator Superfamily
MDIOCMKF_01336 4.3e-152 S haloacid dehalogenase-like hydrolase
MDIOCMKF_01337 2.4e-07
MDIOCMKF_01338 8.1e-179 D Alpha beta
MDIOCMKF_01339 6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
MDIOCMKF_01340 3.9e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MDIOCMKF_01341 2.9e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MDIOCMKF_01342 9.2e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDIOCMKF_01343 7.8e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
MDIOCMKF_01344 2.4e-112 ygaC J Belongs to the UPF0374 family
MDIOCMKF_01345 4.9e-90
MDIOCMKF_01346 3e-78
MDIOCMKF_01347 1.6e-157 hlyX S Transporter associated domain
MDIOCMKF_01348 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDIOCMKF_01349 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
MDIOCMKF_01350 0.0 clpE O Belongs to the ClpA ClpB family
MDIOCMKF_01351 6.9e-26
MDIOCMKF_01352 1.2e-39 ptsH G phosphocarrier protein HPR
MDIOCMKF_01353 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDIOCMKF_01354 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDIOCMKF_01355 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MDIOCMKF_01356 1.7e-162 coiA 3.6.4.12 S Competence protein
MDIOCMKF_01357 7e-107 yjbH Q Thioredoxin
MDIOCMKF_01358 3.3e-112 yjbK S CYTH
MDIOCMKF_01359 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
MDIOCMKF_01360 5.2e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDIOCMKF_01361 3.7e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDIOCMKF_01362 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MDIOCMKF_01363 3.9e-234 N Uncharacterized conserved protein (DUF2075)
MDIOCMKF_01364 4.8e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MDIOCMKF_01365 9.9e-67 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MDIOCMKF_01366 5.4e-212 yubA S AI-2E family transporter
MDIOCMKF_01367 2.7e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDIOCMKF_01368 4.6e-76 WQ51_03320 S Protein of unknown function (DUF1149)
MDIOCMKF_01369 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MDIOCMKF_01370 7.2e-228 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
MDIOCMKF_01371 8.3e-232 S Peptidase M16
MDIOCMKF_01372 1.6e-129 IQ Enoyl-(Acyl carrier protein) reductase
MDIOCMKF_01373 4.3e-125 ymfM S Helix-turn-helix domain
MDIOCMKF_01374 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDIOCMKF_01375 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDIOCMKF_01376 1.2e-209 rny S Endoribonuclease that initiates mRNA decay
MDIOCMKF_01377 2.7e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
MDIOCMKF_01378 2.5e-118 yvyE 3.4.13.9 S YigZ family
MDIOCMKF_01379 1.6e-241 comFA L Helicase C-terminal domain protein
MDIOCMKF_01380 5.7e-126 comFC S Competence protein
MDIOCMKF_01381 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDIOCMKF_01382 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDIOCMKF_01383 6.2e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDIOCMKF_01384 2.5e-35
MDIOCMKF_01385 3.8e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDIOCMKF_01386 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDIOCMKF_01387 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MDIOCMKF_01388 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDIOCMKF_01389 2.2e-179 K Transcriptional regulator
MDIOCMKF_01390 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
MDIOCMKF_01391 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MDIOCMKF_01392 7.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDIOCMKF_01393 7.2e-124 yoaK S Protein of unknown function (DUF1275)
MDIOCMKF_01394 1.4e-228 XK27_04775 S PAS domain
MDIOCMKF_01395 6.4e-105 S Iron-sulfur cluster assembly protein
MDIOCMKF_01396 5.3e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDIOCMKF_01397 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MDIOCMKF_01398 1.2e-64
MDIOCMKF_01399 5.7e-17 IQ reductase
MDIOCMKF_01400 6.6e-57 higA K Helix-turn-helix XRE-family like proteins
MDIOCMKF_01401 1.6e-62 L COG1961 Site-specific recombinases, DNA invertase Pin homologs
MDIOCMKF_01402 3.8e-70 Z012_06740 S Fic/DOC family
MDIOCMKF_01403 5.6e-75 S Fic/DOC family
MDIOCMKF_01404 1.2e-26 licT K CAT RNA binding domain
MDIOCMKF_01405 1e-19 licT K transcriptional antiterminator
MDIOCMKF_01406 4.8e-131 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_01408 2e-163 yvgN C Aldo keto reductase
MDIOCMKF_01409 8.1e-249 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MDIOCMKF_01412 0.0 rafA 3.2.1.22 G alpha-galactosidase
MDIOCMKF_01413 7e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDIOCMKF_01414 4.3e-195 KL domain protein
MDIOCMKF_01415 1.7e-75 KL domain protein
MDIOCMKF_01416 1.4e-122 KL domain protein
MDIOCMKF_01417 2.1e-83
MDIOCMKF_01420 7.2e-197 ampC V Beta-lactamase
MDIOCMKF_01421 4.9e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
MDIOCMKF_01441 4.1e-147 S hydrolase
MDIOCMKF_01442 3.2e-103 yagU S Protein of unknown function (DUF1440)
MDIOCMKF_01443 1.2e-143 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MDIOCMKF_01444 3.1e-119 K Helix-turn-helix XRE-family like proteins
MDIOCMKF_01445 2e-227 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDIOCMKF_01446 3.3e-52 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MDIOCMKF_01447 1.2e-48 L bacterial-type proximal promoter sequence-specific DNA binding
MDIOCMKF_01448 1.2e-74 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
MDIOCMKF_01449 5.4e-122 L oxidized base lesion DNA N-glycosylase activity
MDIOCMKF_01450 6e-13
MDIOCMKF_01451 1.7e-243 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDIOCMKF_01452 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDIOCMKF_01453 1.8e-120 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDIOCMKF_01454 5.5e-49 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDIOCMKF_01455 3.4e-97 S Protein of unknown function (DUF3990)
MDIOCMKF_01456 4.3e-46
MDIOCMKF_01457 7.5e-242 clcA P chloride
MDIOCMKF_01458 7.2e-107
MDIOCMKF_01459 6.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDIOCMKF_01460 1.3e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MDIOCMKF_01461 2.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MDIOCMKF_01462 5.8e-86 folT S ECF transporter, substrate-specific component
MDIOCMKF_01463 3.3e-127 fat 3.1.2.21 I Acyl-ACP thioesterase
MDIOCMKF_01464 8.2e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDIOCMKF_01465 4.9e-57 yabA L Involved in initiation control of chromosome replication
MDIOCMKF_01466 1.5e-150 holB 2.7.7.7 L DNA polymerase III
MDIOCMKF_01467 1e-51 yaaQ S Cyclic-di-AMP receptor
MDIOCMKF_01468 1.6e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDIOCMKF_01469 5.3e-26 S Protein of unknown function (DUF2508)
MDIOCMKF_01470 1.8e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDIOCMKF_01471 1.7e-51 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDIOCMKF_01472 5.5e-309 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDIOCMKF_01473 8.4e-81 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDIOCMKF_01474 1.9e-23
MDIOCMKF_01475 3.9e-113 rsmC 2.1.1.172 J Methyltransferase
MDIOCMKF_01476 5.3e-31
MDIOCMKF_01477 2e-94 L hmm pf00665
MDIOCMKF_01478 3.4e-67 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MDIOCMKF_01479 4.3e-40 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDIOCMKF_01480 4.5e-199 G PTS system sugar-specific permease component
MDIOCMKF_01481 2.6e-35 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MDIOCMKF_01482 5.6e-73 S Uncharacterised protein family UPF0047
MDIOCMKF_01483 1.4e-62 kdsD 5.3.1.13 M SIS domain
MDIOCMKF_01484 1.3e-40 5.3.1.27 M SIS domain
MDIOCMKF_01485 3.2e-163 2.7.1.202 GKT Mga helix-turn-helix domain
MDIOCMKF_01487 2.1e-68 L PFAM transposase, IS4 family protein
MDIOCMKF_01488 3.1e-70 L PFAM transposase, IS4 family protein
MDIOCMKF_01489 8.2e-149 kcsA P Ion transport protein
MDIOCMKF_01490 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDIOCMKF_01491 3.1e-96 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDIOCMKF_01492 2.9e-145 aatB ET ABC transporter substrate-binding protein
MDIOCMKF_01493 4.4e-115 glnQ 3.6.3.21 E ABC transporter
MDIOCMKF_01494 2.5e-107 glnP P ABC transporter permease
MDIOCMKF_01495 1.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDIOCMKF_01496 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDIOCMKF_01497 5.8e-100 nusG K Participates in transcription elongation, termination and antitermination
MDIOCMKF_01498 9.1e-12 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDIOCMKF_01499 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDIOCMKF_01500 1.4e-189 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDIOCMKF_01501 6.9e-226 G Major Facilitator Superfamily
MDIOCMKF_01502 1.9e-239 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDIOCMKF_01503 2.4e-81 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDIOCMKF_01504 3.7e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MDIOCMKF_01505 2.7e-285 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MDIOCMKF_01506 1.7e-34
MDIOCMKF_01507 4.6e-97 yvrI K sigma factor activity
MDIOCMKF_01508 2.3e-286 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
MDIOCMKF_01509 2.3e-288 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
MDIOCMKF_01510 1.9e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
MDIOCMKF_01511 1.3e-151 lacT K PRD domain
MDIOCMKF_01512 1.2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDIOCMKF_01513 3.8e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDIOCMKF_01514 1.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDIOCMKF_01515 9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDIOCMKF_01516 9.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDIOCMKF_01517 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MDIOCMKF_01518 1.8e-256 pepC 3.4.22.40 E Peptidase C1-like family
MDIOCMKF_01519 2.9e-184 S AAA domain
MDIOCMKF_01520 5.2e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDIOCMKF_01521 1.6e-25
MDIOCMKF_01522 4.4e-42
MDIOCMKF_01523 3.4e-155 czcD P cation diffusion facilitator family transporter
MDIOCMKF_01524 2.6e-52 K Transcriptional regulator, ArsR family
MDIOCMKF_01525 9.6e-129 pgm3 G Belongs to the phosphoglycerate mutase family
MDIOCMKF_01526 3.8e-110 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MDIOCMKF_01527 3.5e-160 1.6.5.2 GM NmrA-like family
MDIOCMKF_01528 1.2e-79
MDIOCMKF_01529 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MDIOCMKF_01530 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDIOCMKF_01531 3.5e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDIOCMKF_01532 3.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDIOCMKF_01533 7e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDIOCMKF_01534 5.1e-156 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDIOCMKF_01535 1.3e-61 rplQ J Ribosomal protein L17
MDIOCMKF_01536 1.3e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDIOCMKF_01537 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDIOCMKF_01538 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDIOCMKF_01539 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MDIOCMKF_01540 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDIOCMKF_01541 5.9e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDIOCMKF_01542 2.2e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDIOCMKF_01543 1.3e-70 rplO J Binds to the 23S rRNA
MDIOCMKF_01544 1.4e-23 rpmD J Ribosomal protein L30
MDIOCMKF_01545 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDIOCMKF_01546 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDIOCMKF_01547 5e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDIOCMKF_01548 2.7e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDIOCMKF_01549 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDIOCMKF_01550 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDIOCMKF_01551 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDIOCMKF_01552 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDIOCMKF_01553 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDIOCMKF_01554 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MDIOCMKF_01555 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDIOCMKF_01556 3.9e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDIOCMKF_01557 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDIOCMKF_01558 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDIOCMKF_01559 1.4e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDIOCMKF_01560 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDIOCMKF_01561 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
MDIOCMKF_01562 2.2e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDIOCMKF_01563 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MDIOCMKF_01564 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDIOCMKF_01565 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDIOCMKF_01566 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDIOCMKF_01567 2.4e-108 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MDIOCMKF_01568 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDIOCMKF_01569 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDIOCMKF_01570 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDIOCMKF_01572 1.6e-08
MDIOCMKF_01573 6.3e-63 pipD E Dipeptidase
MDIOCMKF_01574 6.3e-122 pipD E Dipeptidase
MDIOCMKF_01575 7.2e-158 L COG2963 Transposase and inactivated derivatives
MDIOCMKF_01576 6.6e-150 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MDIOCMKF_01578 6.5e-10
MDIOCMKF_01579 2.1e-138 rpiR1 K Helix-turn-helix domain, rpiR family
MDIOCMKF_01580 2.4e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MDIOCMKF_01581 0.0 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
MDIOCMKF_01582 1.4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
MDIOCMKF_01583 2.4e-51
MDIOCMKF_01584 7.6e-24
MDIOCMKF_01585 5.3e-68 pgm3 G Phosphoglycerate mutase family
MDIOCMKF_01586 1.5e-40 pgm3 G Phosphoglycerate mutase family
MDIOCMKF_01587 0.0 V FtsX-like permease family
MDIOCMKF_01588 3.5e-132 cysA V ABC transporter, ATP-binding protein
MDIOCMKF_01589 4.7e-279 E amino acid
MDIOCMKF_01590 3.5e-121 V ABC-2 type transporter
MDIOCMKF_01591 8.4e-123 V Transport permease protein
MDIOCMKF_01592 4.5e-135 V ABC transporter
MDIOCMKF_01593 5.7e-26
MDIOCMKF_01594 1.5e-32
MDIOCMKF_01596 7.3e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDIOCMKF_01597 2.5e-225 S Putative peptidoglycan binding domain
MDIOCMKF_01598 9.5e-102 M NlpC P60 family protein
MDIOCMKF_01599 2.7e-97 gmk2 2.7.4.8 F Guanylate kinase
MDIOCMKF_01600 9e-44
MDIOCMKF_01601 1.2e-264 S O-antigen ligase like membrane protein
MDIOCMKF_01602 1.3e-108
MDIOCMKF_01603 2.7e-79 nrdI F NrdI Flavodoxin like
MDIOCMKF_01604 1e-171 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDIOCMKF_01605 2.1e-77
MDIOCMKF_01606 6.8e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDIOCMKF_01607 3.1e-40
MDIOCMKF_01608 1.3e-79 S Threonine/Serine exporter, ThrE
MDIOCMKF_01609 1.1e-136 thrE S Putative threonine/serine exporter
MDIOCMKF_01610 3.4e-283 S ABC transporter, ATP-binding protein
MDIOCMKF_01611 3.5e-59
MDIOCMKF_01612 4.4e-37
MDIOCMKF_01613 7.4e-211 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDIOCMKF_01614 0.0 pepF E oligoendopeptidase F
MDIOCMKF_01615 2e-70 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_01616 1.8e-249 lctP C L-lactate permease
MDIOCMKF_01617 2.2e-129 znuB U ABC 3 transport family
MDIOCMKF_01618 4.4e-115 fhuC P ABC transporter
MDIOCMKF_01619 4.4e-150 psaA P Belongs to the bacterial solute-binding protein 9 family
MDIOCMKF_01620 1.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
MDIOCMKF_01621 2.3e-134 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
MDIOCMKF_01622 0.0 M domain protein
MDIOCMKF_01623 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
MDIOCMKF_01624 3.4e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MDIOCMKF_01625 8.4e-134 fruR K DeoR C terminal sensor domain
MDIOCMKF_01626 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MDIOCMKF_01627 3.3e-204 natB CP ABC-2 family transporter protein
MDIOCMKF_01628 1.8e-159 natA S ABC transporter, ATP-binding protein
MDIOCMKF_01629 9.7e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MDIOCMKF_01630 1.1e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDIOCMKF_01631 6.4e-202 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
MDIOCMKF_01632 7.4e-121 K response regulator
MDIOCMKF_01633 0.0 V ABC transporter
MDIOCMKF_01634 6.8e-41 V ABC transporter, ATP-binding protein
MDIOCMKF_01635 1.1e-219 V ABC transporter, ATP-binding protein
MDIOCMKF_01636 1.1e-121 XK27_01040 S Protein of unknown function (DUF1129)
MDIOCMKF_01637 5.7e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDIOCMKF_01638 1.1e-42 yyzM S Bacterial protein of unknown function (DUF951)
MDIOCMKF_01639 2.2e-154 spo0J K Belongs to the ParB family
MDIOCMKF_01640 3.3e-138 soj D Sporulation initiation inhibitor
MDIOCMKF_01641 1.4e-140 noc K Belongs to the ParB family
MDIOCMKF_01642 4.4e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MDIOCMKF_01643 4.1e-95 cvpA S Colicin V production protein
MDIOCMKF_01644 2e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDIOCMKF_01645 1.2e-146 3.1.3.48 T Tyrosine phosphatase family
MDIOCMKF_01646 1.4e-192 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MDIOCMKF_01647 7.1e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
MDIOCMKF_01648 1.5e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
MDIOCMKF_01649 2.9e-108 K WHG domain
MDIOCMKF_01650 1e-37
MDIOCMKF_01651 3.2e-264 pipD E Dipeptidase
MDIOCMKF_01652 1.2e-293 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDIOCMKF_01653 2.1e-295 2.7.1.211 G phosphotransferase system
MDIOCMKF_01654 1.2e-157 K CAT RNA binding domain
MDIOCMKF_01655 6.2e-112 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MDIOCMKF_01656 1.7e-169 hrtB V ABC transporter permease
MDIOCMKF_01657 5.6e-89 ygfC K Bacterial regulatory proteins, tetR family
MDIOCMKF_01658 1.1e-107 G phosphoglycerate mutase
MDIOCMKF_01659 1.7e-111 G Phosphoglycerate mutase family
MDIOCMKF_01660 5.2e-136 aroD S Alpha/beta hydrolase family
MDIOCMKF_01661 2.6e-101 S Protein of unknown function (DUF975)
MDIOCMKF_01662 1.4e-128 S Belongs to the UPF0246 family
MDIOCMKF_01663 2.2e-52
MDIOCMKF_01664 1.6e-123
MDIOCMKF_01665 9.2e-156 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MDIOCMKF_01666 2.7e-308 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
MDIOCMKF_01667 7.3e-138 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
MDIOCMKF_01668 4.1e-153 ybbH_2 K Helix-turn-helix domain, rpiR family
MDIOCMKF_01669 2.3e-147 2.7.7.12 C Domain of unknown function (DUF4931)
MDIOCMKF_01670 1e-16 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_01671 3.4e-42 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDIOCMKF_01672 1.7e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDIOCMKF_01673 8.7e-226 ecsB U ABC transporter
MDIOCMKF_01674 2.4e-133 ecsA V ABC transporter, ATP-binding protein
MDIOCMKF_01675 2.4e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
MDIOCMKF_01676 2e-64
MDIOCMKF_01677 4.4e-37 S YtxH-like protein
MDIOCMKF_01678 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDIOCMKF_01679 1.6e-185 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDIOCMKF_01680 0.0 L AAA domain
MDIOCMKF_01681 1.6e-230 yhaO L Ser Thr phosphatase family protein
MDIOCMKF_01682 3.3e-56 yheA S Belongs to the UPF0342 family
MDIOCMKF_01683 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MDIOCMKF_01684 1.8e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDIOCMKF_01686 1.3e-259 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
MDIOCMKF_01687 1.3e-66
MDIOCMKF_01688 2e-94 3.6.1.55 L NUDIX domain
MDIOCMKF_01689 2.2e-153 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
MDIOCMKF_01690 3.9e-198 V Beta-lactamase
MDIOCMKF_01691 8.4e-63
MDIOCMKF_01692 0.0 L helicase activity
MDIOCMKF_01693 6.4e-227 K DNA binding
MDIOCMKF_01694 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
MDIOCMKF_01695 1.8e-127 mod 2.1.1.72, 3.1.21.5 L DNA methylase
MDIOCMKF_01696 1.5e-115 mod 2.1.1.72, 3.1.21.5 L DNA methylase
MDIOCMKF_01697 7.4e-39 K Cro/C1-type HTH DNA-binding domain
MDIOCMKF_01698 1.1e-77
MDIOCMKF_01699 6.2e-208
MDIOCMKF_01700 3.2e-36
MDIOCMKF_01701 7.4e-233
MDIOCMKF_01703 2.7e-23
MDIOCMKF_01704 3.4e-12
MDIOCMKF_01705 1.6e-221 L Protein of unknown function (DUF2800)
MDIOCMKF_01706 1.7e-99 S Protein of unknown function (DUF2815)
MDIOCMKF_01707 0.0 polA_2 2.7.7.7 L DNA polymerase
MDIOCMKF_01708 2.8e-69 S Psort location Cytoplasmic, score
MDIOCMKF_01709 0.0 S Phage plasmid primase, P4
MDIOCMKF_01710 2.4e-46 S VRR_NUC
MDIOCMKF_01711 1.3e-257 L SNF2 family N-terminal domain
MDIOCMKF_01712 2.8e-87
MDIOCMKF_01713 1.4e-36
MDIOCMKF_01714 2.2e-245 2.1.1.72 KL DNA methylase
MDIOCMKF_01715 2.3e-113 S Psort location Cytoplasmic, score
MDIOCMKF_01716 6.2e-31 S Domain of unknown function (DUF5049)
MDIOCMKF_01717 2.1e-299 S overlaps another CDS with the same product name
MDIOCMKF_01718 2.5e-247 S Phage portal protein
MDIOCMKF_01719 2.9e-122 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MDIOCMKF_01720 6.3e-221 S Phage capsid family
MDIOCMKF_01721 4.3e-43 S Phage gp6-like head-tail connector protein
MDIOCMKF_01722 9e-68 S Phage head-tail joining protein
MDIOCMKF_01723 3e-69 S Bacteriophage holin family
MDIOCMKF_01724 2.5e-145 M Glycosyl hydrolases family 25
MDIOCMKF_01725 4.3e-36
MDIOCMKF_01726 3.1e-164 L Recombinase zinc beta ribbon domain
MDIOCMKF_01727 7.7e-100 L Recombinase zinc beta ribbon domain
MDIOCMKF_01728 3.8e-290 L Recombinase
MDIOCMKF_01729 2.7e-227
MDIOCMKF_01730 8.7e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDIOCMKF_01731 9.6e-121 spaE S ABC-2 family transporter protein
MDIOCMKF_01732 1.6e-108 mutF V ABC transporter, ATP-binding protein
MDIOCMKF_01733 1.3e-241 nhaC C Na H antiporter NhaC
MDIOCMKF_01734 9.6e-163 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
MDIOCMKF_01735 3.3e-95 S UPF0397 protein
MDIOCMKF_01736 0.0 ykoD P ABC transporter, ATP-binding protein
MDIOCMKF_01737 3.1e-142 cbiQ P cobalt transport
MDIOCMKF_01738 2.7e-118 ybhL S Belongs to the BI1 family
MDIOCMKF_01739 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
MDIOCMKF_01740 4.7e-64 S Domain of unknown function (DUF4430)
MDIOCMKF_01741 8.1e-88 S ECF transporter, substrate-specific component
MDIOCMKF_01742 2.1e-94 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
MDIOCMKF_01743 4.4e-129 L Helix-turn-helix domain
MDIOCMKF_01744 2.3e-23 L hmm pf00665
MDIOCMKF_01745 1.2e-39 L hmm pf00665
MDIOCMKF_01746 9.6e-152 S hydrolase
MDIOCMKF_01748 7.3e-169 yegS 2.7.1.107 G Lipid kinase
MDIOCMKF_01749 1.5e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDIOCMKF_01750 1.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDIOCMKF_01751 4.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDIOCMKF_01752 1.7e-207 camS S sex pheromone
MDIOCMKF_01753 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDIOCMKF_01754 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MDIOCMKF_01755 1.8e-113 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
MDIOCMKF_01756 1.3e-100 S ECF transporter, substrate-specific component
MDIOCMKF_01758 7.4e-85 ydcK S Belongs to the SprT family
MDIOCMKF_01759 7e-135 M Glycosyltransferase sugar-binding region containing DXD motif
MDIOCMKF_01760 1.9e-256 epsU S Polysaccharide biosynthesis protein
MDIOCMKF_01761 4.7e-229 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDIOCMKF_01762 3.7e-219 V ABC transporter transmembrane region
MDIOCMKF_01763 4.8e-229 L Transposase
MDIOCMKF_01764 0.0 comEC S Competence protein ComEC
MDIOCMKF_01765 1.2e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
MDIOCMKF_01766 1.3e-33 rpsT J Binds directly to 16S ribosomal RNA
MDIOCMKF_01767 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDIOCMKF_01768 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDIOCMKF_01769 7.7e-160
MDIOCMKF_01770 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDIOCMKF_01771 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDIOCMKF_01772 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDIOCMKF_01773 1.2e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
MDIOCMKF_01774 6.7e-89 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDIOCMKF_01775 7.4e-78
MDIOCMKF_01776 1.2e-70 S Domain of unknown function (DUF4767)
MDIOCMKF_01777 2.2e-224
MDIOCMKF_01778 2.5e-121 frnE Q DSBA-like thioredoxin domain
MDIOCMKF_01779 9.6e-180 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDIOCMKF_01781 4.9e-75 S HIRAN
MDIOCMKF_01783 7.2e-164 htpX O Peptidase family M48
MDIOCMKF_01784 7e-32
MDIOCMKF_01785 1.4e-223 patA 2.6.1.1 E Aminotransferase
MDIOCMKF_01786 6.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MDIOCMKF_01787 2.4e-144 E GDSL-like Lipase/Acylhydrolase family
MDIOCMKF_01788 3.8e-107 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDIOCMKF_01789 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDIOCMKF_01790 1e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDIOCMKF_01791 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MDIOCMKF_01792 4.1e-40 yqeY S YqeY-like protein
MDIOCMKF_01793 4e-173 phoH T phosphate starvation-inducible protein PhoH
MDIOCMKF_01794 1.2e-91 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDIOCMKF_01795 1.3e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDIOCMKF_01796 1.6e-137 recO L Involved in DNA repair and RecF pathway recombination
MDIOCMKF_01797 1.8e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MDIOCMKF_01798 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MDIOCMKF_01799 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDIOCMKF_01800 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDIOCMKF_01801 2.5e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
MDIOCMKF_01802 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDIOCMKF_01803 1.6e-246 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MDIOCMKF_01804 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
MDIOCMKF_01805 3.3e-124 skfE V ATPases associated with a variety of cellular activities
MDIOCMKF_01806 2.1e-138
MDIOCMKF_01807 2.3e-108
MDIOCMKF_01808 8.1e-22
MDIOCMKF_01809 1e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MDIOCMKF_01810 4e-133
MDIOCMKF_01811 1.1e-167
MDIOCMKF_01812 1.5e-229 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
MDIOCMKF_01813 3.5e-52 ybjQ S Belongs to the UPF0145 family
MDIOCMKF_01814 1.1e-160 XK27_05540 S DUF218 domain
MDIOCMKF_01815 5.1e-153 yxeH S hydrolase
MDIOCMKF_01816 2.3e-303 I Protein of unknown function (DUF2974)
MDIOCMKF_01817 2.7e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDIOCMKF_01818 1.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDIOCMKF_01819 6.8e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDIOCMKF_01820 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDIOCMKF_01821 2.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MDIOCMKF_01822 2.8e-32 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MDIOCMKF_01823 3.1e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDIOCMKF_01824 1.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MDIOCMKF_01825 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MDIOCMKF_01826 3.3e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDIOCMKF_01827 3.6e-27 pncA Q Isochorismatase family
MDIOCMKF_01828 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MDIOCMKF_01829 5.7e-126 alkD L DNA alkylation repair enzyme
MDIOCMKF_01831 2.9e-128 XK27_06785 V ABC transporter, ATP-binding protein
MDIOCMKF_01832 0.0 XK27_06780 V ABC transporter permease
MDIOCMKF_01833 0.0 pepO 3.4.24.71 O Peptidase family M13
MDIOCMKF_01834 4.8e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
MDIOCMKF_01835 2.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDIOCMKF_01836 3.3e-283 thrC 4.2.3.1 E Threonine synthase
MDIOCMKF_01837 2.7e-230 hom1 1.1.1.3 E homoserine dehydrogenase
MDIOCMKF_01838 3.3e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDIOCMKF_01839 1.1e-167 lysR7 K LysR substrate binding domain
MDIOCMKF_01840 0.0 1.3.5.4 C FMN_bind
MDIOCMKF_01841 8.4e-119 drgA C nitroreductase
MDIOCMKF_01842 2.8e-28
MDIOCMKF_01843 8.7e-23
MDIOCMKF_01844 6.5e-10
MDIOCMKF_01845 1.4e-72
MDIOCMKF_01846 2e-205 EGP Major facilitator Superfamily
MDIOCMKF_01847 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
MDIOCMKF_01848 1.4e-107 vanZ V VanZ like family
MDIOCMKF_01849 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDIOCMKF_01850 5.3e-270 T PhoQ Sensor
MDIOCMKF_01851 9e-130 K Transcriptional regulatory protein, C terminal
MDIOCMKF_01852 9.2e-68 S SdpI/YhfL protein family
MDIOCMKF_01853 2.9e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
MDIOCMKF_01854 1.8e-80 patB 4.4.1.8 E Aminotransferase, class I
MDIOCMKF_01855 1e-76 M Protein of unknown function (DUF3737)
MDIOCMKF_01856 2.1e-226 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
MDIOCMKF_01857 1.8e-47 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
MDIOCMKF_01858 1.4e-132 sip L Belongs to the 'phage' integrase family
MDIOCMKF_01859 7.3e-13 S sequence-specific DNA binding
MDIOCMKF_01860 4.8e-20
MDIOCMKF_01862 1.5e-10
MDIOCMKF_01864 2.9e-28
MDIOCMKF_01865 1.9e-35 S Primase C terminal 1 (PriCT-1)
MDIOCMKF_01866 1.4e-84 S DNA primase
MDIOCMKF_01869 5e-09
MDIOCMKF_01871 3.6e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDIOCMKF_01872 1.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
MDIOCMKF_01873 4.7e-88 comGF U Putative Competence protein ComGF
MDIOCMKF_01875 7e-66
MDIOCMKF_01876 1.1e-36 comGC U Required for transformation and DNA binding
MDIOCMKF_01877 4.7e-177 comGB NU type II secretion system
MDIOCMKF_01878 5.8e-180 comGA NU Type II IV secretion system protein
MDIOCMKF_01879 1.5e-132 yebC K Transcriptional regulatory protein
MDIOCMKF_01880 7.3e-97 S VanZ like family
MDIOCMKF_01881 3.7e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDIOCMKF_01882 4.5e-163 znuA P Belongs to the bacterial solute-binding protein 9 family
MDIOCMKF_01883 8.5e-150 yisY 1.11.1.10 S Alpha/beta hydrolase family
MDIOCMKF_01884 4.8e-115
MDIOCMKF_01885 3.1e-178 S Putative adhesin
MDIOCMKF_01886 5.3e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDIOCMKF_01887 2.3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDIOCMKF_01888 3.8e-148 S Sucrose-6F-phosphate phosphohydrolase
MDIOCMKF_01889 2.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDIOCMKF_01890 8.1e-174 ybbR S YbbR-like protein
MDIOCMKF_01891 3.4e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDIOCMKF_01892 1.3e-209 potD P ABC transporter
MDIOCMKF_01893 8.5e-137 potC P ABC transporter permease
MDIOCMKF_01894 2.7e-130 potB P ABC transporter permease
MDIOCMKF_01895 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDIOCMKF_01896 4.4e-166 murB 1.3.1.98 M Cell wall formation
MDIOCMKF_01897 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
MDIOCMKF_01898 1.3e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MDIOCMKF_01899 2.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MDIOCMKF_01900 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDIOCMKF_01901 8e-157 ycsE S Sucrose-6F-phosphate phosphohydrolase
MDIOCMKF_01902 2.9e-93
MDIOCMKF_01903 6.6e-91
MDIOCMKF_01905 1e-107 3.2.2.20 K acetyltransferase
MDIOCMKF_01906 2.3e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDIOCMKF_01907 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDIOCMKF_01908 2.5e-28 secG U Preprotein translocase
MDIOCMKF_01909 1.2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDIOCMKF_01910 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDIOCMKF_01911 6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MDIOCMKF_01912 1.6e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDIOCMKF_01913 2.3e-187 cggR K Putative sugar-binding domain
MDIOCMKF_01915 1.2e-277 ycaM E amino acid
MDIOCMKF_01916 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDIOCMKF_01917 6.2e-171 whiA K May be required for sporulation
MDIOCMKF_01918 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MDIOCMKF_01919 6e-160 rapZ S Displays ATPase and GTPase activities
MDIOCMKF_01920 1.1e-90 S Short repeat of unknown function (DUF308)
MDIOCMKF_01921 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDIOCMKF_01922 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDIOCMKF_01923 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MDIOCMKF_01924 1.6e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MDIOCMKF_01925 5.2e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MDIOCMKF_01926 1.4e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDIOCMKF_01927 9.2e-181 lacR K Transcriptional regulator

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)