ORF_ID e_value Gene_name EC_number CAZy COGs Description
HPOEDDCO_00005 2.8e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPOEDDCO_00006 7.7e-253 qacA EGP Major facilitator Superfamily
HPOEDDCO_00007 9.7e-115 3.6.1.27 I Acid phosphatase homologues
HPOEDDCO_00008 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPOEDDCO_00009 2.7e-302 ytgP S Polysaccharide biosynthesis protein
HPOEDDCO_00010 2.2e-202 I Protein of unknown function (DUF2974)
HPOEDDCO_00011 1.3e-123
HPOEDDCO_00012 1.1e-142 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPOEDDCO_00013 4.4e-118 M ErfK YbiS YcfS YnhG
HPOEDDCO_00014 2.8e-155 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPOEDDCO_00015 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HPOEDDCO_00016 6.5e-173 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HPOEDDCO_00017 7e-42
HPOEDDCO_00018 6.8e-30 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
HPOEDDCO_00019 5.2e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HPOEDDCO_00021 2.1e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HPOEDDCO_00022 1.5e-126 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
HPOEDDCO_00023 4e-105 ylbE GM NAD(P)H-binding
HPOEDDCO_00024 1.2e-79 yebR 1.8.4.14 T GAF domain-containing protein
HPOEDDCO_00025 1.4e-189 S Bacteriocin helveticin-J
HPOEDDCO_00026 3e-96 tag 3.2.2.20 L glycosylase
HPOEDDCO_00027 5.8e-153 mleP3 S Membrane transport protein
HPOEDDCO_00028 7.6e-130 S CAAX amino terminal protease
HPOEDDCO_00029 1.5e-143 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPOEDDCO_00030 1.1e-254 emrY EGP Major facilitator Superfamily
HPOEDDCO_00031 2.8e-255 emrY EGP Major facilitator Superfamily
HPOEDDCO_00032 6.2e-256 V ABC-type multidrug transport system, ATPase and permease components
HPOEDDCO_00033 8.3e-277 V ABC-type multidrug transport system, ATPase and permease components
HPOEDDCO_00034 9.1e-21
HPOEDDCO_00035 1.8e-231 4.2.1.53 S Myosin-crossreactive antigen
HPOEDDCO_00036 3.8e-75 2.3.1.128 K acetyltransferase
HPOEDDCO_00037 9e-131 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HPOEDDCO_00038 7.5e-141 S hydrolase
HPOEDDCO_00039 7.8e-133 K Transcriptional regulator
HPOEDDCO_00040 5.5e-24 S PFAM Archaeal ATPase
HPOEDDCO_00041 6.2e-241 pyrP F Permease
HPOEDDCO_00042 7.6e-135 lacR K DeoR C terminal sensor domain
HPOEDDCO_00043 9.4e-74 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HPOEDDCO_00044 2.1e-105 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HPOEDDCO_00045 1.6e-128 S Domain of unknown function (DUF4867)
HPOEDDCO_00046 2.3e-84 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPOEDDCO_00047 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HPOEDDCO_00048 1.8e-267 gatC G PTS system sugar-specific permease component
HPOEDDCO_00049 1.3e-38
HPOEDDCO_00050 2e-144 lacT K CAT RNA binding domain
HPOEDDCO_00051 3.6e-55 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HPOEDDCO_00052 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HPOEDDCO_00053 4.5e-290 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HPOEDDCO_00054 4.5e-163 K LysR family
HPOEDDCO_00055 0.0 1.3.5.4 C FMN_bind
HPOEDDCO_00056 3.7e-260 P Sodium:sulfate symporter transmembrane region
HPOEDDCO_00057 1.5e-164 glsA 3.5.1.2 E Belongs to the glutaminase family
HPOEDDCO_00058 7.4e-73 K Helix-turn-helix domain, rpiR family
HPOEDDCO_00059 1.1e-176 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPOEDDCO_00060 5.8e-143 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPOEDDCO_00061 0.0 yesZ 3.2.1.23 G -beta-galactosidase
HPOEDDCO_00062 5.8e-160 gph G MFS/sugar transport protein
HPOEDDCO_00063 3.5e-125 I alpha/beta hydrolase fold
HPOEDDCO_00064 6.6e-144 cah5 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HPOEDDCO_00065 2.5e-99 bgaR K helix_turn_helix, arabinose operon control protein
HPOEDDCO_00066 2.2e-158 4.2.2.23 PL4 E Polysaccharide lyase family 4, domain III
HPOEDDCO_00067 1.3e-234 G MFS/sugar transport protein
HPOEDDCO_00068 1.4e-110 3.6.1.27 I Acid phosphatase homologues
HPOEDDCO_00069 3.3e-274 E Phospholipase B
HPOEDDCO_00070 4.3e-250 pepC 3.4.22.40 E Peptidase C1-like family
HPOEDDCO_00071 2.5e-276 gadC E Contains amino acid permease domain
HPOEDDCO_00072 3e-238 yagE E amino acid
HPOEDDCO_00073 2.1e-249 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HPOEDDCO_00074 9.5e-141 potD2 P ABC transporter
HPOEDDCO_00075 1.8e-150 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPOEDDCO_00076 2e-114 potC3 E Binding-protein-dependent transport system inner membrane component
HPOEDDCO_00077 5.1e-108 potB E Binding-protein-dependent transport system inner membrane component
HPOEDDCO_00078 1.4e-69 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_00079 1.5e-292 E Amino acid permease
HPOEDDCO_00080 1.7e-213 mdtG EGP Major facilitator Superfamily
HPOEDDCO_00081 4.1e-30
HPOEDDCO_00082 2.4e-69 K helix_turn_helix multiple antibiotic resistance protein
HPOEDDCO_00083 1.6e-79
HPOEDDCO_00084 3.4e-205 pepA E M42 glutamyl aminopeptidase
HPOEDDCO_00086 5.8e-252 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HPOEDDCO_00087 3.1e-262 aaxC E Arginine ornithine antiporter
HPOEDDCO_00088 3.9e-248 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HPOEDDCO_00089 0.0 lacA 3.2.1.23 G -beta-galactosidase
HPOEDDCO_00090 1.8e-265 dtpT U amino acid peptide transporter
HPOEDDCO_00091 1.9e-207 naiP EGP Major facilitator Superfamily
HPOEDDCO_00092 1.3e-143 S Alpha beta hydrolase
HPOEDDCO_00093 7.9e-68 K Transcriptional regulator, MarR family
HPOEDDCO_00094 3.7e-302 XK27_09600 V ABC transporter, ATP-binding protein
HPOEDDCO_00095 0.0 V ABC transporter transmembrane region
HPOEDDCO_00096 1.1e-144 glnH ET ABC transporter
HPOEDDCO_00097 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPOEDDCO_00098 2.1e-146 glnH ET ABC transporter
HPOEDDCO_00099 3.2e-110 gluC P ABC transporter permease
HPOEDDCO_00100 9.8e-107 glnP P ABC transporter permease
HPOEDDCO_00101 6.1e-43 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_00102 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HPOEDDCO_00103 4.7e-126 treR K UTRA
HPOEDDCO_00104 0.0 treB 2.7.1.211 G phosphotransferase system
HPOEDDCO_00105 3.5e-82 S Putative adhesin
HPOEDDCO_00106 8.9e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HPOEDDCO_00107 1.5e-205 EGP Major facilitator superfamily
HPOEDDCO_00109 3e-187 2.7.13.3 T GHKL domain
HPOEDDCO_00110 1.6e-122 K LytTr DNA-binding domain
HPOEDDCO_00111 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HPOEDDCO_00112 3.6e-84 M Transport protein ComB
HPOEDDCO_00113 7.8e-11
HPOEDDCO_00117 6.5e-31 S Enterocin A Immunity
HPOEDDCO_00118 8.4e-34 blpT
HPOEDDCO_00122 3.1e-50 S Enterocin A Immunity
HPOEDDCO_00123 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HPOEDDCO_00124 2.3e-156 rssA S Phospholipase, patatin family
HPOEDDCO_00125 2.2e-255 glnPH2 P ABC transporter permease
HPOEDDCO_00126 4.3e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPOEDDCO_00127 5.5e-92 K Acetyltransferase (GNAT) domain
HPOEDDCO_00128 2.1e-157 pstS P Phosphate
HPOEDDCO_00129 2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HPOEDDCO_00130 8.3e-157 pstA P Phosphate transport system permease protein PstA
HPOEDDCO_00131 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPOEDDCO_00132 6e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPOEDDCO_00133 7.6e-118 phoU P Plays a role in the regulation of phosphate uptake
HPOEDDCO_00134 2.1e-280 S C4-dicarboxylate anaerobic carrier
HPOEDDCO_00135 2.2e-84 dps P Belongs to the Dps family
HPOEDDCO_00137 2e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPOEDDCO_00138 1.1e-124 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPOEDDCO_00139 2e-166 rihB 3.2.2.1 F Nucleoside
HPOEDDCO_00140 4e-133 gntR K UbiC transcription regulator-associated domain protein
HPOEDDCO_00141 7.7e-52 S Enterocin A Immunity
HPOEDDCO_00142 3.6e-132 glcR K DeoR C terminal sensor domain
HPOEDDCO_00143 3.3e-48 yceE S haloacid dehalogenase-like hydrolase
HPOEDDCO_00144 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HPOEDDCO_00145 4.7e-117 C nitroreductase
HPOEDDCO_00146 1.1e-127
HPOEDDCO_00147 3.2e-248 yhdP S Transporter associated domain
HPOEDDCO_00148 2.7e-100 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HPOEDDCO_00149 3e-232 potE E amino acid
HPOEDDCO_00150 6.4e-136 M Glycosyl hydrolases family 25
HPOEDDCO_00151 7.1e-199 yfmL 3.6.4.13 L DEAD DEAH box helicase
HPOEDDCO_00152 5.2e-248 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPOEDDCO_00154 4.4e-216 S Phage integrase family
HPOEDDCO_00156 5.5e-99 S Domain of Unknown Function with PDB structure (DUF3862)
HPOEDDCO_00157 2.1e-87 S Pfam:Peptidase_M78
HPOEDDCO_00158 3.1e-56 xre K Helix-turn-helix domain
HPOEDDCO_00160 6e-60 S Domain of unknown function (DUF771)
HPOEDDCO_00162 1.8e-19
HPOEDDCO_00163 1e-56
HPOEDDCO_00165 5.7e-149 S Protein of unknown function (DUF1071)
HPOEDDCO_00166 1e-170 S Conserved phage C-terminus (Phg_2220_C)
HPOEDDCO_00167 5.4e-15 S sequence-specific DNA binding
HPOEDDCO_00168 2.5e-138 S AntA/AntB antirepressor
HPOEDDCO_00169 8.1e-26
HPOEDDCO_00171 6.2e-63 S Pfam:DUF5406
HPOEDDCO_00172 9.8e-15
HPOEDDCO_00173 6.3e-43
HPOEDDCO_00175 1e-65
HPOEDDCO_00176 1.9e-80 S Endodeoxyribonuclease RusA
HPOEDDCO_00177 1.2e-14
HPOEDDCO_00178 1.7e-25
HPOEDDCO_00179 1.5e-17
HPOEDDCO_00180 9.5e-19
HPOEDDCO_00181 9.2e-89
HPOEDDCO_00183 1.7e-19 S N-methyltransferase activity
HPOEDDCO_00184 5e-96 S N-methyltransferase activity
HPOEDDCO_00185 9.8e-43
HPOEDDCO_00186 1.5e-86 S peptidase activity
HPOEDDCO_00187 1.9e-244 S DNA packaging
HPOEDDCO_00188 2.3e-270 S Phage portal protein, SPP1 Gp6-like
HPOEDDCO_00189 4.4e-299 S Phage Mu protein F like protein
HPOEDDCO_00191 6.9e-93 S Phage minor structural protein GP20
HPOEDDCO_00192 2.2e-204
HPOEDDCO_00193 3.8e-66
HPOEDDCO_00194 6.3e-63
HPOEDDCO_00195 2e-79 S Bacteriophage HK97-gp10, putative tail-component
HPOEDDCO_00196 2.3e-69
HPOEDDCO_00197 1.1e-30
HPOEDDCO_00198 2.8e-249 xkdK S Phage tail sheath C-terminal domain
HPOEDDCO_00199 4.5e-85 xkdM S Phage tail tube protein
HPOEDDCO_00200 1.4e-69 xkdN S Phage XkdN-like tail assembly chaperone protein, TAC
HPOEDDCO_00201 1.9e-246 S phage tail tape measure protein
HPOEDDCO_00202 1.6e-112 ygaU GH23 S protein containing LysM domain
HPOEDDCO_00203 2.2e-201 S N-acetylmuramoyl-L-alanine amidase activity
HPOEDDCO_00204 5e-60 S Protein of unknown function (DUF2577)
HPOEDDCO_00205 1.4e-62 S Protein of unknown function (DUF2634)
HPOEDDCO_00206 2.3e-215 S Baseplate J-like protein
HPOEDDCO_00207 1.3e-96 S Uncharacterised protein conserved in bacteria (DUF2313)
HPOEDDCO_00208 0.0 S N-acetylmuramoyl-L-alanine amidase activity
HPOEDDCO_00209 6.1e-88
HPOEDDCO_00211 2.3e-64
HPOEDDCO_00212 3.3e-43
HPOEDDCO_00213 7.7e-68 S Pfam:Phage_holin_6_1
HPOEDDCO_00214 4.3e-180 S N-acetylmuramoyl-L-alanine amidase activity
HPOEDDCO_00215 6.8e-212 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HPOEDDCO_00216 9.1e-84 gtcA S Teichoic acid glycosylation protein
HPOEDDCO_00217 2.1e-76 fld C Flavodoxin
HPOEDDCO_00218 1.9e-160 map 3.4.11.18 E Methionine Aminopeptidase
HPOEDDCO_00219 2.8e-155 yihY S Belongs to the UPF0761 family
HPOEDDCO_00220 2.3e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HPOEDDCO_00221 1.4e-124 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_00222 1.2e-07 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_00223 3.3e-175 E ABC transporter, ATP-binding protein
HPOEDDCO_00224 9e-284 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HPOEDDCO_00225 9e-66 O OsmC-like protein
HPOEDDCO_00226 1.6e-111 2.7.6.5 T Region found in RelA / SpoT proteins
HPOEDDCO_00227 5.8e-115 K response regulator
HPOEDDCO_00228 4.1e-226 sptS 2.7.13.3 T Histidine kinase
HPOEDDCO_00229 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HPOEDDCO_00230 5.2e-82
HPOEDDCO_00231 0.0 pepN 3.4.11.2 E aminopeptidase
HPOEDDCO_00232 5e-134 S haloacid dehalogenase-like hydrolase
HPOEDDCO_00234 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPOEDDCO_00235 1.9e-66
HPOEDDCO_00236 7.2e-101 fic D Fic/DOC family
HPOEDDCO_00237 2.8e-210 I transferase activity, transferring acyl groups other than amino-acyl groups
HPOEDDCO_00238 8.6e-215 S Phage integrase family
HPOEDDCO_00241 4.1e-57 S Hypothetical protein (DUF2513)
HPOEDDCO_00242 5.7e-17 S Pfam:Peptidase_M78
HPOEDDCO_00243 4.1e-17 ps115 K sequence-specific DNA binding
HPOEDDCO_00244 1.8e-19 K Helix-turn-helix XRE-family like proteins
HPOEDDCO_00246 8.3e-92 K ORF6N domain
HPOEDDCO_00247 9.5e-27
HPOEDDCO_00250 2e-15
HPOEDDCO_00252 3e-23
HPOEDDCO_00253 9.1e-16
HPOEDDCO_00256 3.1e-71 S AAA domain
HPOEDDCO_00257 2.6e-255 S helicase activity
HPOEDDCO_00259 7.4e-97 S Protein of unknown function (DUF669)
HPOEDDCO_00260 0.0 S hydrolase activity
HPOEDDCO_00262 2e-39 S sequence-specific DNA binding
HPOEDDCO_00264 1e-33
HPOEDDCO_00267 3.9e-65
HPOEDDCO_00271 1.9e-43 S VRR_NUC
HPOEDDCO_00272 2.8e-31 S sequence-specific DNA binding transcription factor activity
HPOEDDCO_00274 9.4e-75 arpU S Phage transcriptional regulator, ArpU family
HPOEDDCO_00275 7.2e-89 S HNH endonuclease
HPOEDDCO_00276 3.9e-78 S Phage terminase, small subunit
HPOEDDCO_00277 1.5e-237 S Phage Terminase
HPOEDDCO_00279 3.4e-158 S Phage portal protein
HPOEDDCO_00280 2.7e-118 S Clp protease
HPOEDDCO_00281 1.3e-218 S peptidase activity
HPOEDDCO_00282 8.1e-37 S Phage gp6-like head-tail connector protein
HPOEDDCO_00284 7.7e-08 S Bacteriophage HK97-gp10, putative tail-component
HPOEDDCO_00286 4.7e-08 S Pfam:Phage_TTP_1
HPOEDDCO_00288 0.0 M Phage tail tape measure protein TP901
HPOEDDCO_00289 2.7e-145 S Phage tail protein
HPOEDDCO_00290 2.7e-214 S Phage minor structural protein
HPOEDDCO_00291 1.6e-147 S N-acetylmuramoyl-L-alanine amidase activity
HPOEDDCO_00294 6.2e-08
HPOEDDCO_00297 2.3e-120 lysA2 M Glycosyl hydrolases family 25
HPOEDDCO_00298 2.8e-125 pnb C nitroreductase
HPOEDDCO_00299 1.2e-84 S Domain of unknown function (DUF4811)
HPOEDDCO_00300 1.2e-261 lmrB EGP Major facilitator Superfamily
HPOEDDCO_00301 1e-67 K MerR HTH family regulatory protein
HPOEDDCO_00302 0.0 oppA E ABC transporter substrate-binding protein
HPOEDDCO_00303 2.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HPOEDDCO_00304 2.6e-252 pepC 3.4.22.40 E Peptidase C1-like family
HPOEDDCO_00305 4.9e-165 2.7.1.2 GK ROK family
HPOEDDCO_00306 2.1e-157 rhaS6 K helix_turn_helix, arabinose operon control protein
HPOEDDCO_00307 2e-174 I Carboxylesterase family
HPOEDDCO_00308 5.6e-185 yhjX P Major Facilitator Superfamily
HPOEDDCO_00309 6.2e-281 S Predicted membrane protein (DUF2207)
HPOEDDCO_00310 6e-55 K Acetyltransferase (GNAT) domain
HPOEDDCO_00311 1.2e-52
HPOEDDCO_00312 6.6e-119 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HPOEDDCO_00313 2.9e-91 S ECF-type riboflavin transporter, S component
HPOEDDCO_00314 3.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HPOEDDCO_00315 3.5e-12
HPOEDDCO_00316 7.8e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
HPOEDDCO_00317 3.3e-147 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPOEDDCO_00318 2.9e-60 arsC 1.20.4.1 P Belongs to the ArsC family
HPOEDDCO_00319 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HPOEDDCO_00320 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HPOEDDCO_00321 2.6e-192 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HPOEDDCO_00322 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPOEDDCO_00323 2.2e-73 yqhY S Asp23 family, cell envelope-related function
HPOEDDCO_00324 1.7e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPOEDDCO_00325 1.2e-152 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPOEDDCO_00326 2.2e-249 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPOEDDCO_00327 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPOEDDCO_00328 6.8e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPOEDDCO_00329 6.6e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HPOEDDCO_00330 8.9e-253 recN L May be involved in recombinational repair of damaged DNA
HPOEDDCO_00331 8.8e-47
HPOEDDCO_00332 8.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HPOEDDCO_00333 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPOEDDCO_00334 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPOEDDCO_00335 1.4e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPOEDDCO_00336 1.3e-230 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPOEDDCO_00337 1e-139 stp 3.1.3.16 T phosphatase
HPOEDDCO_00338 0.0 KLT serine threonine protein kinase
HPOEDDCO_00339 1.2e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPOEDDCO_00340 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HPOEDDCO_00341 6.9e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
HPOEDDCO_00342 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HPOEDDCO_00343 1.4e-57 asp S Asp23 family, cell envelope-related function
HPOEDDCO_00344 2.4e-306 yloV S DAK2 domain fusion protein YloV
HPOEDDCO_00345 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPOEDDCO_00346 1.7e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPOEDDCO_00347 2.6e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPOEDDCO_00348 5.3e-192 oppD P Belongs to the ABC transporter superfamily
HPOEDDCO_00349 7.6e-180 oppF P Belongs to the ABC transporter superfamily
HPOEDDCO_00350 2.9e-179 oppB P ABC transporter permease
HPOEDDCO_00351 7.9e-163 oppC P Binding-protein-dependent transport system inner membrane component
HPOEDDCO_00352 0.0 oppA E ABC transporter substrate-binding protein
HPOEDDCO_00353 0.0 oppA E ABC transporter substrate-binding protein
HPOEDDCO_00354 6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPOEDDCO_00355 0.0 smc D Required for chromosome condensation and partitioning
HPOEDDCO_00356 1.8e-163 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPOEDDCO_00357 3.5e-282 pipD E Dipeptidase
HPOEDDCO_00358 7e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HPOEDDCO_00359 1.4e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPOEDDCO_00360 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HPOEDDCO_00361 2.3e-90 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPOEDDCO_00362 1.5e-132 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HPOEDDCO_00363 1.3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPOEDDCO_00364 1.3e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPOEDDCO_00365 8.2e-70 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HPOEDDCO_00366 4.2e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
HPOEDDCO_00367 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPOEDDCO_00368 1.2e-33 ynzC S UPF0291 protein
HPOEDDCO_00369 1.9e-30 yneF S Uncharacterised protein family (UPF0154)
HPOEDDCO_00370 0.0 mdlA V ABC transporter
HPOEDDCO_00371 5.5e-293 mdlB V ABC transporter
HPOEDDCO_00372 2.1e-224 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HPOEDDCO_00373 1.4e-115 plsC 2.3.1.51 I Acyltransferase
HPOEDDCO_00374 6.5e-190 yabB 2.1.1.223 L Methyltransferase small domain
HPOEDDCO_00375 1.1e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
HPOEDDCO_00376 2.5e-181 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPOEDDCO_00377 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HPOEDDCO_00378 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPOEDDCO_00379 1.4e-130 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPOEDDCO_00380 1e-137 cdsA 2.7.7.41 S Belongs to the CDS family
HPOEDDCO_00381 2.5e-228 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HPOEDDCO_00382 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPOEDDCO_00383 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPOEDDCO_00384 4e-81 rimP J Required for maturation of 30S ribosomal subunits
HPOEDDCO_00385 2.5e-196 nusA K Participates in both transcription termination and antitermination
HPOEDDCO_00386 1.5e-46 ylxR K Protein of unknown function (DUF448)
HPOEDDCO_00387 8.7e-45 rplGA J ribosomal protein
HPOEDDCO_00388 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPOEDDCO_00389 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPOEDDCO_00390 7.2e-161 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPOEDDCO_00391 2.8e-171 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HPOEDDCO_00392 1.5e-259 lsa S ABC transporter
HPOEDDCO_00393 8.2e-111 S GyrI-like small molecule binding domain
HPOEDDCO_00394 3.2e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPOEDDCO_00395 3.2e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPOEDDCO_00396 0.0 dnaK O Heat shock 70 kDa protein
HPOEDDCO_00397 1e-170 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPOEDDCO_00398 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPOEDDCO_00399 3.9e-122 srtA 3.4.22.70 M sortase family
HPOEDDCO_00400 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HPOEDDCO_00401 2.3e-59 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPOEDDCO_00402 1.4e-22 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPOEDDCO_00403 2.2e-274 yjeM E Amino Acid
HPOEDDCO_00404 9.2e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPOEDDCO_00405 2.9e-184 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPOEDDCO_00406 1.7e-85 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPOEDDCO_00407 1.5e-92 G Major Facilitator
HPOEDDCO_00408 2.6e-141 G Major Facilitator
HPOEDDCO_00409 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HPOEDDCO_00410 1.7e-151 lysR5 K LysR substrate binding domain
HPOEDDCO_00412 2.1e-100 3.6.1.27 I Acid phosphatase homologues
HPOEDDCO_00413 1.6e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPOEDDCO_00414 1.2e-22 S Sugar efflux transporter for intercellular exchange
HPOEDDCO_00415 4.3e-305 ybiT S ABC transporter, ATP-binding protein
HPOEDDCO_00416 4.5e-164 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPOEDDCO_00417 3.9e-40 K Helix-turn-helix domain
HPOEDDCO_00418 5.3e-137 F DNA/RNA non-specific endonuclease
HPOEDDCO_00419 8.5e-43 L nuclease
HPOEDDCO_00420 2.5e-155 metQ1 P Belongs to the nlpA lipoprotein family
HPOEDDCO_00421 6.9e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPOEDDCO_00422 1.4e-66 metI P ABC transporter permease
HPOEDDCO_00423 1.2e-263 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HPOEDDCO_00424 2.6e-250 frdC 1.3.5.4 C FAD binding domain
HPOEDDCO_00425 1.3e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPOEDDCO_00426 1e-254 yjjP S Putative threonine/serine exporter
HPOEDDCO_00427 6.7e-187 ansA 3.5.1.1 EJ L-asparaginase, type I
HPOEDDCO_00428 0.0 aha1 P E1-E2 ATPase
HPOEDDCO_00429 1.3e-299 S Bacterial membrane protein, YfhO
HPOEDDCO_00430 6.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPOEDDCO_00431 2.6e-164 prmA J Ribosomal protein L11 methyltransferase
HPOEDDCO_00432 1.4e-65
HPOEDDCO_00433 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPOEDDCO_00434 1.7e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPOEDDCO_00435 2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HPOEDDCO_00436 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HPOEDDCO_00437 3.2e-217 patA 2.6.1.1 E Aminotransferase
HPOEDDCO_00438 2.4e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HPOEDDCO_00439 9.6e-138 E GDSL-like Lipase/Acylhydrolase family
HPOEDDCO_00440 6.2e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPOEDDCO_00441 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPOEDDCO_00442 3.9e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HPOEDDCO_00443 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HPOEDDCO_00444 5.6e-37 yqeY S YqeY-like protein
HPOEDDCO_00445 1.8e-173 phoH T phosphate starvation-inducible protein PhoH
HPOEDDCO_00446 4.1e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPOEDDCO_00447 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPOEDDCO_00448 6.8e-136 recO L Involved in DNA repair and RecF pathway recombination
HPOEDDCO_00449 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HPOEDDCO_00450 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HPOEDDCO_00451 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPOEDDCO_00452 1.4e-198 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPOEDDCO_00453 8.4e-109 trmK 2.1.1.217 S SAM-dependent methyltransferase
HPOEDDCO_00454 1.2e-143 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPOEDDCO_00455 1.1e-244 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HPOEDDCO_00456 3.6e-58 yvoA_1 K Transcriptional regulator, GntR family
HPOEDDCO_00457 2.2e-120 skfE V ATPases associated with a variety of cellular activities
HPOEDDCO_00458 2.2e-127
HPOEDDCO_00459 5.6e-115
HPOEDDCO_00460 8.1e-22
HPOEDDCO_00461 1.1e-101 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPOEDDCO_00462 1.7e-106
HPOEDDCO_00463 8.8e-154
HPOEDDCO_00464 8.2e-228 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HPOEDDCO_00465 4.7e-49 ybjQ S Belongs to the UPF0145 family
HPOEDDCO_00466 4.7e-156 XK27_05540 S DUF218 domain
HPOEDDCO_00467 2.5e-147 yxeH S hydrolase
HPOEDDCO_00468 2.3e-298 I Protein of unknown function (DUF2974)
HPOEDDCO_00469 5.4e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPOEDDCO_00470 3.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HPOEDDCO_00471 1.9e-164 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPOEDDCO_00472 1.8e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPOEDDCO_00473 4.1e-170 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HPOEDDCO_00474 2.7e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPOEDDCO_00475 1.3e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HPOEDDCO_00476 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HPOEDDCO_00477 1.3e-55 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPOEDDCO_00478 3.5e-25 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPOEDDCO_00479 3e-101 pncA Q Isochorismatase family
HPOEDDCO_00480 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HPOEDDCO_00481 7.7e-123 alkD L DNA alkylation repair enzyme
HPOEDDCO_00482 6.2e-123 XK27_06785 V ABC transporter, ATP-binding protein
HPOEDDCO_00483 0.0 XK27_06780 V ABC transporter permease
HPOEDDCO_00484 1.7e-91 S Protein of unknown function (DUF554)
HPOEDDCO_00485 1.9e-52 K LysR substrate binding domain
HPOEDDCO_00486 1.8e-244 ubiX 2.5.1.129, 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HPOEDDCO_00487 1.7e-67 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HPOEDDCO_00488 7.3e-22
HPOEDDCO_00489 4.7e-51 M Belongs to the glycosyl hydrolase 28 family
HPOEDDCO_00490 3.8e-12
HPOEDDCO_00491 3.3e-308 pepO 3.4.24.71 O Peptidase family M13
HPOEDDCO_00492 2.6e-32 pepO 3.4.24.71 O Peptidase family M13
HPOEDDCO_00493 1.4e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
HPOEDDCO_00494 3.5e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPOEDDCO_00495 2.2e-263 thrC 4.2.3.1 E Threonine synthase
HPOEDDCO_00496 1.5e-209 hom1 1.1.1.3 E homoserine dehydrogenase
HPOEDDCO_00497 1.5e-147 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPOEDDCO_00498 3.4e-158 lysR7 K LysR substrate binding domain
HPOEDDCO_00499 0.0 1.3.5.4 C FMN_bind
HPOEDDCO_00500 1.6e-117 drgA C nitroreductase
HPOEDDCO_00501 2e-26
HPOEDDCO_00502 1.5e-35 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPOEDDCO_00503 2.3e-33 K CAT RNA binding domain
HPOEDDCO_00504 3.1e-166 G phosphotransferase system, EIIB
HPOEDDCO_00505 1.7e-86 G YdjC-like protein
HPOEDDCO_00506 2e-67 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HPOEDDCO_00507 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HPOEDDCO_00508 1.1e-117
HPOEDDCO_00509 8.7e-56 speG J Acetyltransferase (GNAT) domain
HPOEDDCO_00510 1e-59 K sequence-specific DNA binding
HPOEDDCO_00511 1.7e-129 S Protein of unknown function (DUF975)
HPOEDDCO_00512 2e-126 qmcA O prohibitin homologues
HPOEDDCO_00513 9.6e-136 ropB K Helix-turn-helix domain
HPOEDDCO_00514 3.2e-276 V ABC-type multidrug transport system, ATPase and permease components
HPOEDDCO_00515 4.1e-78 C nitroreductase
HPOEDDCO_00516 2.3e-266 V ABC transporter transmembrane region
HPOEDDCO_00517 1.5e-44
HPOEDDCO_00518 1.4e-72 K Acetyltransferase (GNAT) domain
HPOEDDCO_00519 3.1e-47 S MazG-like family
HPOEDDCO_00520 3.6e-58
HPOEDDCO_00521 3.5e-21 S Protein of unknown function (DUF3923)
HPOEDDCO_00522 2.4e-12 S Fic/DOC family
HPOEDDCO_00523 4.6e-94 rimL J Acetyltransferase (GNAT) domain
HPOEDDCO_00524 3.3e-83 2.3.1.57 K Acetyltransferase (GNAT) family
HPOEDDCO_00526 1.1e-09 XK27_07525 3.6.1.55 F NUDIX domain
HPOEDDCO_00527 1e-08 S RelB antitoxin
HPOEDDCO_00528 6.8e-84 S AAA domain
HPOEDDCO_00529 2.4e-67 3.6.1.55 F NUDIX domain
HPOEDDCO_00530 4.9e-134 2.4.2.3 F Phosphorylase superfamily
HPOEDDCO_00531 2.6e-74 6.3.3.2 S ASCH
HPOEDDCO_00532 7.6e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HPOEDDCO_00533 5.4e-156 rbsU U ribose uptake protein RbsU
HPOEDDCO_00534 2.1e-154 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HPOEDDCO_00535 2.9e-269 V ABC-type multidrug transport system, ATPase and permease components
HPOEDDCO_00536 1.3e-250 V ABC-type multidrug transport system, ATPase and permease components
HPOEDDCO_00537 4e-179 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HPOEDDCO_00538 1.5e-200 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HPOEDDCO_00539 3.2e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HPOEDDCO_00540 7.2e-164 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HPOEDDCO_00541 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HPOEDDCO_00542 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HPOEDDCO_00543 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HPOEDDCO_00544 2.1e-85 ypmB S Protein conserved in bacteria
HPOEDDCO_00545 1.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HPOEDDCO_00546 1.3e-106 dnaD L DnaD domain protein
HPOEDDCO_00547 2e-112 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPOEDDCO_00548 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HPOEDDCO_00549 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HPOEDDCO_00550 1.8e-104 ypsA S Belongs to the UPF0398 family
HPOEDDCO_00551 6e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HPOEDDCO_00552 3.9e-212 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HPOEDDCO_00553 1.1e-231 cpdA S Calcineurin-like phosphoesterase
HPOEDDCO_00554 6.8e-170 degV S DegV family
HPOEDDCO_00555 4.8e-52
HPOEDDCO_00556 1e-309 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HPOEDDCO_00557 9.2e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPOEDDCO_00558 9.7e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPOEDDCO_00559 2.8e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HPOEDDCO_00560 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HPOEDDCO_00561 1.5e-308 FbpA K Fibronectin-binding protein
HPOEDDCO_00562 1.6e-62
HPOEDDCO_00563 7.2e-161 degV S EDD domain protein, DegV family
HPOEDDCO_00564 3.6e-146
HPOEDDCO_00565 4.5e-163 K Transcriptional regulator
HPOEDDCO_00566 1.9e-195 xerS L Belongs to the 'phage' integrase family
HPOEDDCO_00567 1.5e-124 yoaK S Protein of unknown function (DUF1275)
HPOEDDCO_00568 1.2e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPOEDDCO_00569 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HPOEDDCO_00570 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
HPOEDDCO_00571 4.4e-172 K Transcriptional regulator
HPOEDDCO_00572 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPOEDDCO_00573 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPOEDDCO_00574 1.1e-113 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPOEDDCO_00575 1.5e-104 lacA 2.3.1.79 S Transferase hexapeptide repeat
HPOEDDCO_00576 2.7e-109 magIII L Base excision DNA repair protein, HhH-GPD family
HPOEDDCO_00577 8.7e-159 akr5f 1.1.1.346 S reductase
HPOEDDCO_00578 6.7e-158 C Aldo/keto reductase family
HPOEDDCO_00579 1.1e-116 ybhL S Belongs to the BI1 family
HPOEDDCO_00580 8.3e-108 4.1.1.45 S Amidohydrolase
HPOEDDCO_00581 1.1e-242 yrvN L AAA C-terminal domain
HPOEDDCO_00582 1.5e-115 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HPOEDDCO_00583 1.5e-78 XK27_09675 K Acetyltransferase (GNAT) domain
HPOEDDCO_00584 3.3e-25 K Acetyltransferase (GNAT) domain
HPOEDDCO_00585 1.2e-194 XK27_00915 C Luciferase-like monooxygenase
HPOEDDCO_00586 4.4e-36 sugE U Multidrug resistance protein
HPOEDDCO_00588 3e-67 S Uncharacterized protein conserved in bacteria (DUF2263)
HPOEDDCO_00589 6.6e-33 S Flavodoxin-like fold
HPOEDDCO_00590 6.7e-74 ogt 2.1.1.63, 3.2.2.20 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HPOEDDCO_00591 1.2e-46 K Transcriptional regulator
HPOEDDCO_00592 7.3e-13 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HPOEDDCO_00593 4.3e-26 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HPOEDDCO_00594 6.1e-78 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HPOEDDCO_00595 1e-90 K Acetyltransferase (GNAT) family
HPOEDDCO_00596 1.3e-111 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HPOEDDCO_00597 1.5e-92 dps P Belongs to the Dps family
HPOEDDCO_00598 1.3e-34 copZ C Heavy-metal-associated domain
HPOEDDCO_00599 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HPOEDDCO_00600 1.1e-08 ybbM S Uncharacterised protein family (UPF0014)
HPOEDDCO_00601 4.9e-103 ybbL S ABC transporter, ATP-binding protein
HPOEDDCO_00602 1e-66 S pyridoxamine 5-phosphate
HPOEDDCO_00603 6.2e-171 yobV1 K WYL domain
HPOEDDCO_00604 1.4e-28 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HPOEDDCO_00605 1.2e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPOEDDCO_00606 4.5e-263 npr 1.11.1.1 C NADH oxidase
HPOEDDCO_00607 2e-29 G Major facilitator Superfamily
HPOEDDCO_00608 3e-58 S Sulfite exporter TauE/SafE
HPOEDDCO_00609 4.6e-214 mdt(A) EGP Major facilitator Superfamily
HPOEDDCO_00610 1.4e-116 GM NAD(P)H-binding
HPOEDDCO_00611 2.1e-229 E Alpha/beta hydrolase of unknown function (DUF1100)
HPOEDDCO_00612 9.2e-101 K Transcriptional regulator C-terminal region
HPOEDDCO_00614 6.4e-148 C Aldo keto reductase
HPOEDDCO_00615 2.8e-92 lmrA 3.6.3.44 V ABC transporter
HPOEDDCO_00616 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HPOEDDCO_00617 0.0 uvrA3 L excinuclease ABC, A subunit
HPOEDDCO_00618 3.8e-12 mta K helix_turn_helix, mercury resistance
HPOEDDCO_00619 4.2e-75 mta K helix_turn_helix, mercury resistance
HPOEDDCO_00620 1.5e-211 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HPOEDDCO_00621 2.2e-127 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HPOEDDCO_00622 1.1e-155 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPOEDDCO_00623 1.1e-11 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPOEDDCO_00624 5.2e-243 brnQ U Component of the transport system for branched-chain amino acids
HPOEDDCO_00625 1.5e-73 yphH S Cupin domain
HPOEDDCO_00626 1e-109 S Fic/DOC family
HPOEDDCO_00627 6.9e-39 S Protein of unknown function (DUF3021)
HPOEDDCO_00628 1.5e-45 K LytTr DNA-binding domain
HPOEDDCO_00629 2.6e-91 cylB V ABC-2 type transporter
HPOEDDCO_00630 5.7e-115 cylA V ABC transporter
HPOEDDCO_00631 3.1e-279 V ABC-type multidrug transport system, ATPase and permease components
HPOEDDCO_00632 3.4e-270 P ABC transporter
HPOEDDCO_00633 6e-96 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HPOEDDCO_00634 2.8e-84 S Domain of unknown function (DUF1788)
HPOEDDCO_00635 6.5e-73 S Putative inner membrane protein (DUF1819)
HPOEDDCO_00636 1.9e-115 S PFAM Archaeal ATPase
HPOEDDCO_00637 1.6e-247 brnQ U Component of the transport system for branched-chain amino acids
HPOEDDCO_00638 5.8e-55 S Putative adhesin
HPOEDDCO_00639 1.6e-119 3.6.1.55 F NUDIX domain
HPOEDDCO_00640 1.8e-107 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPOEDDCO_00641 1.3e-246
HPOEDDCO_00642 0.0 M domain protein
HPOEDDCO_00643 0.0 bamA UW LPXTG-motif cell wall anchor domain protein
HPOEDDCO_00645 0.0 S domain, Protein
HPOEDDCO_00646 9.9e-102 S Protein of unknown function (DUF1211)
HPOEDDCO_00647 7.6e-71 K LytTr DNA-binding domain
HPOEDDCO_00648 1.7e-48 S Protein of unknown function (DUF3021)
HPOEDDCO_00649 5.3e-114 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HPOEDDCO_00650 7.4e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HPOEDDCO_00651 6.4e-126 ybbM S Uncharacterised protein family (UPF0014)
HPOEDDCO_00652 1.1e-102 ybbL S ABC transporter, ATP-binding protein
HPOEDDCO_00653 1.2e-112 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_00654 2.4e-40
HPOEDDCO_00655 2.1e-46
HPOEDDCO_00656 3e-223 lsa S ABC transporter
HPOEDDCO_00657 2.1e-37 S Uncharacterized protein conserved in bacteria (DUF2255)
HPOEDDCO_00658 8.6e-190 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HPOEDDCO_00659 1.7e-85 S NADPH-dependent FMN reductase
HPOEDDCO_00660 2.4e-145 K Transcriptional regulator
HPOEDDCO_00661 1.9e-78 tanA S alpha beta
HPOEDDCO_00662 4.6e-98 tanA S alpha beta
HPOEDDCO_00663 6e-39 K LysR substrate binding domain
HPOEDDCO_00664 3.2e-176 MA20_14895 S Conserved hypothetical protein 698
HPOEDDCO_00665 1.4e-54
HPOEDDCO_00667 1.9e-98 S LexA-binding, inner membrane-associated putative hydrolase
HPOEDDCO_00668 1e-94 K LysR substrate binding domain
HPOEDDCO_00669 1.4e-175 lacX 5.1.3.3 G Aldose 1-epimerase
HPOEDDCO_00670 2.4e-235 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HPOEDDCO_00671 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HPOEDDCO_00672 9.8e-169 xerC D Phage integrase, N-terminal SAM-like domain
HPOEDDCO_00673 1.3e-243 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HPOEDDCO_00674 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPOEDDCO_00675 1.3e-151 dprA LU DNA protecting protein DprA
HPOEDDCO_00676 9.5e-130 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPOEDDCO_00677 1.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HPOEDDCO_00678 2.4e-262 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HPOEDDCO_00679 2e-35 yozE S Belongs to the UPF0346 family
HPOEDDCO_00680 2.7e-149 DegV S Uncharacterised protein, DegV family COG1307
HPOEDDCO_00681 7.6e-115 hlyIII S protein, hemolysin III
HPOEDDCO_00682 9.9e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPOEDDCO_00683 1.8e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPOEDDCO_00684 1.3e-293 1.3.5.4 C FMN_bind
HPOEDDCO_00685 4.6e-35 1.3.5.4 C FMN_bind
HPOEDDCO_00686 5.1e-80 kch J Ion transport protein
HPOEDDCO_00688 3.3e-293 N Uncharacterized conserved protein (DUF2075)
HPOEDDCO_00690 2.1e-230 S Tetratricopeptide repeat protein
HPOEDDCO_00691 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPOEDDCO_00692 3.6e-241 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HPOEDDCO_00693 3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
HPOEDDCO_00694 1.5e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HPOEDDCO_00695 2.9e-97 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPOEDDCO_00696 2.2e-46 M Lysin motif
HPOEDDCO_00697 1.5e-127 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPOEDDCO_00698 5.4e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPOEDDCO_00699 3.4e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPOEDDCO_00700 2.6e-61 ribT K acetyltransferase
HPOEDDCO_00701 1.1e-167 xerD D recombinase XerD
HPOEDDCO_00702 1.1e-164 cvfB S S1 domain
HPOEDDCO_00703 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HPOEDDCO_00704 3.6e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HPOEDDCO_00705 0.0 dnaE 2.7.7.7 L DNA polymerase
HPOEDDCO_00706 2.1e-28 S Protein of unknown function (DUF2929)
HPOEDDCO_00707 2.3e-303 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HPOEDDCO_00708 5e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HPOEDDCO_00709 8.2e-46 yrvD S Lipopolysaccharide assembly protein A domain
HPOEDDCO_00710 7.4e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPOEDDCO_00711 4.1e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HPOEDDCO_00712 0.0 oatA I Acyltransferase
HPOEDDCO_00713 1.9e-239 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPOEDDCO_00714 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPOEDDCO_00715 6.1e-171 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HPOEDDCO_00716 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
HPOEDDCO_00717 2.5e-107 GM NmrA-like family
HPOEDDCO_00718 7.2e-245 yagE E amino acid
HPOEDDCO_00719 4.3e-80 S Rib/alpha-like repeat
HPOEDDCO_00720 4.2e-57 S Domain of unknown function DUF1828
HPOEDDCO_00721 1.2e-65
HPOEDDCO_00722 2.2e-26
HPOEDDCO_00723 5.9e-79 mutT 3.6.1.55 F NUDIX domain
HPOEDDCO_00724 1.7e-58
HPOEDDCO_00725 7.4e-161 htpX O Peptidase family M48
HPOEDDCO_00726 3.8e-75 S HIRAN
HPOEDDCO_00727 7.4e-12 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HPOEDDCO_00728 3.8e-90 K IrrE N-terminal-like domain
HPOEDDCO_00729 3.8e-27
HPOEDDCO_00730 6.5e-187 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HPOEDDCO_00731 2e-117 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HPOEDDCO_00732 2e-83 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPOEDDCO_00733 1.5e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
HPOEDDCO_00734 7.2e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPOEDDCO_00735 6.1e-204 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPOEDDCO_00736 5.6e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPOEDDCO_00737 4.7e-157
HPOEDDCO_00738 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPOEDDCO_00739 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPOEDDCO_00740 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HPOEDDCO_00741 3.5e-172 holA 2.7.7.7 L DNA polymerase III delta subunit
HPOEDDCO_00742 0.0 comEC S Competence protein ComEC
HPOEDDCO_00743 6.1e-59 comEA L Competence protein ComEA
HPOEDDCO_00744 2.5e-173 ylbL T Belongs to the peptidase S16 family
HPOEDDCO_00745 5.8e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPOEDDCO_00746 1.7e-91 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HPOEDDCO_00747 1.4e-48 ylbG S UPF0298 protein
HPOEDDCO_00748 4.3e-209 ftsW D Belongs to the SEDS family
HPOEDDCO_00749 0.0 typA T GTP-binding protein TypA
HPOEDDCO_00750 2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPOEDDCO_00751 1.1e-33 ykzG S Belongs to the UPF0356 family
HPOEDDCO_00752 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPOEDDCO_00753 1.1e-162 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HPOEDDCO_00754 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HPOEDDCO_00755 6e-112 S Repeat protein
HPOEDDCO_00756 9.9e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HPOEDDCO_00757 2.4e-217 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPOEDDCO_00758 2.4e-56 XK27_04120 S Putative amino acid metabolism
HPOEDDCO_00759 6e-208 iscS 2.8.1.7 E Aminotransferase class V
HPOEDDCO_00760 5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPOEDDCO_00761 6.9e-09
HPOEDDCO_00762 1.3e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HPOEDDCO_00763 3.3e-32 cspA K 'Cold-shock' DNA-binding domain
HPOEDDCO_00764 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPOEDDCO_00765 1.1e-115 gpsB D DivIVA domain protein
HPOEDDCO_00766 3.5e-138 ylmH S S4 domain protein
HPOEDDCO_00767 2e-27 yggT S YGGT family
HPOEDDCO_00768 4e-72 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPOEDDCO_00769 2.1e-228 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPOEDDCO_00770 2.3e-235 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPOEDDCO_00771 3.6e-149 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HPOEDDCO_00772 5.8e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPOEDDCO_00773 1.4e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPOEDDCO_00774 1.3e-176 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPOEDDCO_00775 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HPOEDDCO_00776 6.3e-55 ftsL D Cell division protein FtsL
HPOEDDCO_00777 2.9e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPOEDDCO_00778 7.7e-76 mraZ K Belongs to the MraZ family
HPOEDDCO_00779 5.1e-51 S Protein of unknown function (DUF3397)
HPOEDDCO_00780 3.6e-13 S Protein of unknown function (DUF4044)
HPOEDDCO_00781 5e-93 mreD
HPOEDDCO_00782 1.8e-140 mreC M Involved in formation and maintenance of cell shape
HPOEDDCO_00783 2.1e-164 mreB D cell shape determining protein MreB
HPOEDDCO_00784 5.2e-110 radC L DNA repair protein
HPOEDDCO_00785 2.8e-120 S Haloacid dehalogenase-like hydrolase
HPOEDDCO_00786 7.9e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HPOEDDCO_00787 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPOEDDCO_00788 0.0 3.6.3.8 P P-type ATPase
HPOEDDCO_00789 2.6e-184 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HPOEDDCO_00790 1.9e-108 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPOEDDCO_00791 2.7e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPOEDDCO_00792 4e-212 iscS2 2.8.1.7 E Aminotransferase class V
HPOEDDCO_00793 5.7e-295 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HPOEDDCO_00795 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPOEDDCO_00796 3.3e-80 yueI S Protein of unknown function (DUF1694)
HPOEDDCO_00797 6e-233 rarA L recombination factor protein RarA
HPOEDDCO_00799 2e-80 usp6 T universal stress protein
HPOEDDCO_00800 4.7e-224 rodA D Belongs to the SEDS family
HPOEDDCO_00801 1.3e-34 S Protein of unknown function (DUF2969)
HPOEDDCO_00802 7.6e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HPOEDDCO_00803 1.5e-15 S DNA-directed RNA polymerase subunit beta
HPOEDDCO_00804 8.5e-179 mbl D Cell shape determining protein MreB Mrl
HPOEDDCO_00805 2.3e-29 ywzB S Protein of unknown function (DUF1146)
HPOEDDCO_00806 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HPOEDDCO_00807 7.4e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPOEDDCO_00808 2.7e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPOEDDCO_00809 6.7e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPOEDDCO_00810 1.4e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPOEDDCO_00811 5.1e-47 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPOEDDCO_00812 1.2e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPOEDDCO_00813 1.2e-126 atpB C it plays a direct role in the translocation of protons across the membrane
HPOEDDCO_00814 8.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPOEDDCO_00815 6.1e-185 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPOEDDCO_00816 5.8e-152 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPOEDDCO_00817 1.9e-195 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPOEDDCO_00818 1e-110 tdk 2.7.1.21 F thymidine kinase
HPOEDDCO_00819 1.6e-257 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HPOEDDCO_00820 6.1e-196 ampC V Beta-lactamase
HPOEDDCO_00823 3.7e-65
HPOEDDCO_00824 3.4e-210 EGP Major facilitator Superfamily
HPOEDDCO_00825 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
HPOEDDCO_00826 7.2e-104 vanZ V VanZ like family
HPOEDDCO_00827 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPOEDDCO_00828 6.5e-268 T PhoQ Sensor
HPOEDDCO_00829 2.9e-128 K Transcriptional regulatory protein, C terminal
HPOEDDCO_00830 7.3e-65 S SdpI/YhfL protein family
HPOEDDCO_00831 6.1e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
HPOEDDCO_00832 3.7e-189 patB 4.4.1.8 E Aminotransferase, class I
HPOEDDCO_00833 4.6e-75 M Protein of unknown function (DUF3737)
HPOEDDCO_00834 2.9e-214 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HPOEDDCO_00837 2.8e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPOEDDCO_00838 1.4e-181 ytxK 2.1.1.72 L N-6 DNA Methylase
HPOEDDCO_00839 6.4e-83 comGF U Putative Competence protein ComGF
HPOEDDCO_00840 3.5e-65
HPOEDDCO_00841 5.4e-36 comGC U Required for transformation and DNA binding
HPOEDDCO_00842 4.4e-167 comGB NU type II secretion system
HPOEDDCO_00843 2.2e-163 comGA NU Type II IV secretion system protein
HPOEDDCO_00844 4.4e-132 yebC K Transcriptional regulatory protein
HPOEDDCO_00845 3.6e-96 S VanZ like family
HPOEDDCO_00846 3.4e-206 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPOEDDCO_00847 3.2e-35 znuA P Belongs to the bacterial solute-binding protein 9 family
HPOEDDCO_00848 2.1e-91 znuA P Belongs to the bacterial solute-binding protein 9 family
HPOEDDCO_00849 5e-142 yisY 1.11.1.10 S Alpha/beta hydrolase family
HPOEDDCO_00850 6e-110
HPOEDDCO_00851 9.5e-172 S Putative adhesin
HPOEDDCO_00852 4.2e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPOEDDCO_00853 8e-64 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPOEDDCO_00854 3.5e-138 S Sucrose-6F-phosphate phosphohydrolase
HPOEDDCO_00855 5.9e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPOEDDCO_00856 2.2e-171 ybbR S YbbR-like protein
HPOEDDCO_00857 4.5e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPOEDDCO_00858 4e-206 potD P ABC transporter
HPOEDDCO_00859 2.2e-137 potC P ABC transporter permease
HPOEDDCO_00860 3e-129 potB P ABC transporter permease
HPOEDDCO_00861 5.9e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPOEDDCO_00862 8.4e-165 murB 1.3.1.98 M Cell wall formation
HPOEDDCO_00863 2.3e-98 dnaQ 2.7.7.7 L DNA polymerase III
HPOEDDCO_00864 5.2e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HPOEDDCO_00865 2.1e-174 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HPOEDDCO_00866 1.2e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPOEDDCO_00867 1.4e-153 ycsE S Sucrose-6F-phosphate phosphohydrolase
HPOEDDCO_00868 1.1e-92
HPOEDDCO_00869 2.8e-89
HPOEDDCO_00871 5.2e-104 3.2.2.20 K acetyltransferase
HPOEDDCO_00872 1.1e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPOEDDCO_00873 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPOEDDCO_00874 2.5e-28 secG U Preprotein translocase
HPOEDDCO_00875 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPOEDDCO_00876 2.7e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPOEDDCO_00877 6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HPOEDDCO_00878 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPOEDDCO_00879 2.6e-186 cggR K Putative sugar-binding domain
HPOEDDCO_00881 2.6e-277 ycaM E amino acid
HPOEDDCO_00882 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPOEDDCO_00883 2.6e-169 whiA K May be required for sporulation
HPOEDDCO_00884 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HPOEDDCO_00885 6e-160 rapZ S Displays ATPase and GTPase activities
HPOEDDCO_00886 3.1e-90 S Short repeat of unknown function (DUF308)
HPOEDDCO_00887 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPOEDDCO_00888 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPOEDDCO_00889 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HPOEDDCO_00890 3.4e-188 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HPOEDDCO_00891 3.2e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HPOEDDCO_00892 1.3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HPOEDDCO_00893 5.2e-176 lacR K Transcriptional regulator
HPOEDDCO_00894 3.7e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPOEDDCO_00895 5.2e-170 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPOEDDCO_00896 1.1e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HPOEDDCO_00897 4.3e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPOEDDCO_00898 1.6e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HPOEDDCO_00899 2.1e-34
HPOEDDCO_00900 2.9e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPOEDDCO_00901 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPOEDDCO_00902 1.3e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPOEDDCO_00903 1.3e-114 comFC S Competence protein
HPOEDDCO_00904 2e-228 comFA L Helicase C-terminal domain protein
HPOEDDCO_00905 1.1e-113 yvyE 3.4.13.9 S YigZ family
HPOEDDCO_00906 3e-191 tagO 2.7.8.33, 2.7.8.35 M transferase
HPOEDDCO_00907 1.7e-208 rny S Endoribonuclease that initiates mRNA decay
HPOEDDCO_00908 2.5e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPOEDDCO_00909 9.7e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPOEDDCO_00910 2.4e-120 ymfM S Helix-turn-helix domain
HPOEDDCO_00911 2.6e-124 IQ Enoyl-(Acyl carrier protein) reductase
HPOEDDCO_00912 2.7e-222 S Peptidase M16
HPOEDDCO_00913 2.2e-221 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HPOEDDCO_00914 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HPOEDDCO_00915 1.9e-74 WQ51_03320 S Protein of unknown function (DUF1149)
HPOEDDCO_00916 3.5e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPOEDDCO_00917 1.4e-207 yubA S AI-2E family transporter
HPOEDDCO_00918 6.4e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HPOEDDCO_00919 6.5e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HPOEDDCO_00920 2.9e-221 N Uncharacterized conserved protein (DUF2075)
HPOEDDCO_00921 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HPOEDDCO_00922 5.8e-166 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPOEDDCO_00923 4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPOEDDCO_00924 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
HPOEDDCO_00925 2.9e-108 yjbK S CYTH
HPOEDDCO_00926 3e-102 yjbH Q Thioredoxin
HPOEDDCO_00927 1.9e-153 coiA 3.6.4.12 S Competence protein
HPOEDDCO_00928 1.4e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HPOEDDCO_00929 1.4e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HPOEDDCO_00930 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPOEDDCO_00931 7.2e-40 ptsH G phosphocarrier protein HPR
HPOEDDCO_00932 6.9e-26
HPOEDDCO_00933 0.0 clpE O Belongs to the ClpA ClpB family
HPOEDDCO_00934 7.4e-43 XK27_09445 S Domain of unknown function (DUF1827)
HPOEDDCO_00935 2.8e-301 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPOEDDCO_00936 5.2e-156 hlyX S Transporter associated domain
HPOEDDCO_00937 3.4e-77
HPOEDDCO_00938 2.1e-85
HPOEDDCO_00939 7.8e-111 ygaC J Belongs to the UPF0374 family
HPOEDDCO_00940 8.7e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
HPOEDDCO_00941 1.1e-256 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPOEDDCO_00942 9e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HPOEDDCO_00943 4.1e-207 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HPOEDDCO_00944 2.1e-208 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HPOEDDCO_00945 8.4e-168 D Alpha beta
HPOEDDCO_00946 9.6e-09
HPOEDDCO_00947 3.2e-147 S haloacid dehalogenase-like hydrolase
HPOEDDCO_00948 7.9e-200 EGP Major facilitator Superfamily
HPOEDDCO_00949 1.6e-260 glnA 6.3.1.2 E glutamine synthetase
HPOEDDCO_00950 8.3e-160 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPOEDDCO_00951 8.1e-19 S Protein of unknown function (DUF3042)
HPOEDDCO_00952 4.4e-57 yqhL P Rhodanese-like protein
HPOEDDCO_00953 3e-34 yqgQ S Bacterial protein of unknown function (DUF910)
HPOEDDCO_00954 1.7e-117 gluP 3.4.21.105 S Rhomboid family
HPOEDDCO_00955 4.1e-77 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPOEDDCO_00956 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HPOEDDCO_00957 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HPOEDDCO_00958 0.0 S membrane
HPOEDDCO_00959 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPOEDDCO_00960 1.9e-203 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPOEDDCO_00961 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPOEDDCO_00962 4.5e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPOEDDCO_00963 7.3e-64 yodB K Transcriptional regulator, HxlR family
HPOEDDCO_00964 7.9e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPOEDDCO_00965 5.5e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HPOEDDCO_00966 3e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPOEDDCO_00967 1.5e-278 arlS 2.7.13.3 T Histidine kinase
HPOEDDCO_00968 4.1e-130 K response regulator
HPOEDDCO_00969 8.8e-93 yceD S Uncharacterized ACR, COG1399
HPOEDDCO_00970 6.6e-215 ylbM S Belongs to the UPF0348 family
HPOEDDCO_00971 9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPOEDDCO_00972 7.6e-106 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HPOEDDCO_00973 5.7e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPOEDDCO_00974 3.7e-207 yqeH S Ribosome biogenesis GTPase YqeH
HPOEDDCO_00975 1.6e-88 yqeG S HAD phosphatase, family IIIA
HPOEDDCO_00976 7.1e-173 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HPOEDDCO_00977 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPOEDDCO_00978 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HPOEDDCO_00979 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPOEDDCO_00980 3.3e-130 S domain protein
HPOEDDCO_00981 5.9e-169 V ABC transporter
HPOEDDCO_00982 1.9e-71 S Protein of unknown function (DUF3021)
HPOEDDCO_00983 1.4e-72 K LytTr DNA-binding domain
HPOEDDCO_00985 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPOEDDCO_00986 1e-162 dnaI L Primosomal protein DnaI
HPOEDDCO_00987 1.8e-248 dnaB L Replication initiation and membrane attachment
HPOEDDCO_00988 5.9e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPOEDDCO_00989 3.8e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPOEDDCO_00990 2.1e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HPOEDDCO_00991 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPOEDDCO_00992 9.1e-220 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HPOEDDCO_00993 1.5e-205 EGP Major facilitator Superfamily
HPOEDDCO_00994 2.1e-62 rmaI K Transcriptional regulator
HPOEDDCO_00995 2.7e-46
HPOEDDCO_00996 1.3e-151 levD G PTS system mannose/fructose/sorbose family IID component
HPOEDDCO_00997 3e-140 M PTS system sorbose-specific iic component
HPOEDDCO_00998 1.1e-94 2.7.1.191 G PTS system sorbose subfamily IIB component
HPOEDDCO_00999 6.7e-67 levA G PTS system fructose IIA component
HPOEDDCO_01000 1.6e-145 rbsB G Periplasmic binding protein domain
HPOEDDCO_01001 8.3e-198 baeS F Sensor histidine kinase
HPOEDDCO_01002 5e-114 baeR K helix_turn_helix, Lux Regulon
HPOEDDCO_01003 9e-186 G Bacterial extracellular solute-binding protein
HPOEDDCO_01004 5.7e-124 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HPOEDDCO_01005 7.2e-95 K UTRA
HPOEDDCO_01006 1.5e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HPOEDDCO_01007 1.2e-104 cutC P Participates in the control of copper homeostasis
HPOEDDCO_01008 4.6e-196 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPOEDDCO_01009 9.7e-89 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
HPOEDDCO_01010 3.2e-175 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HPOEDDCO_01011 6.1e-241 3.5.1.18 E Peptidase family M20/M25/M40
HPOEDDCO_01012 4e-125 ymfC K UTRA
HPOEDDCO_01013 1.4e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPOEDDCO_01014 3.4e-52 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HPOEDDCO_01015 1.1e-09
HPOEDDCO_01016 4.7e-69 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_01017 6.3e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPOEDDCO_01018 7.6e-222 ecsB U ABC transporter
HPOEDDCO_01019 1e-131 ecsA V ABC transporter, ATP-binding protein
HPOEDDCO_01020 1.2e-76 hit FG Scavenger mRNA decapping enzyme C-term binding
HPOEDDCO_01021 2.1e-61
HPOEDDCO_01022 2.5e-24 S YtxH-like protein
HPOEDDCO_01023 5.8e-126 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPOEDDCO_01024 1.6e-185 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPOEDDCO_01025 0.0 L AAA domain
HPOEDDCO_01026 2.4e-215 yhaO L Ser Thr phosphatase family protein
HPOEDDCO_01027 3.3e-56 yheA S Belongs to the UPF0342 family
HPOEDDCO_01028 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HPOEDDCO_01029 6e-149 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPOEDDCO_01031 2.2e-254 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HPOEDDCO_01032 6.9e-63
HPOEDDCO_01033 3.4e-86 3.6.1.55 L NUDIX domain
HPOEDDCO_01035 5.4e-184 V Beta-lactamase
HPOEDDCO_01036 4.3e-250 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPOEDDCO_01037 2.3e-114 spaE S ABC-2 family transporter protein
HPOEDDCO_01038 3.4e-129 mutF V ABC transporter, ATP-binding protein
HPOEDDCO_01039 7.5e-242 nhaC C Na H antiporter NhaC
HPOEDDCO_01040 1.7e-159 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HPOEDDCO_01041 2.1e-94 S UPF0397 protein
HPOEDDCO_01042 0.0 ykoD P ABC transporter, ATP-binding protein
HPOEDDCO_01043 2.7e-141 cbiQ P cobalt transport
HPOEDDCO_01044 3.2e-119 ybhL S Belongs to the BI1 family
HPOEDDCO_01045 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HPOEDDCO_01046 1.5e-62 S Domain of unknown function (DUF4430)
HPOEDDCO_01047 2.4e-87 S ECF transporter, substrate-specific component
HPOEDDCO_01048 4.3e-92 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HPOEDDCO_01049 2.2e-153 nss M transferase activity, transferring glycosyl groups
HPOEDDCO_01050 1.9e-108 cpsJ S glycosyl transferase family 2
HPOEDDCO_01051 1.2e-224 GT2,GT4 M family 8
HPOEDDCO_01052 2.7e-97 GT2,GT4 M family 8
HPOEDDCO_01053 2.2e-91 GT2,GT4 M family 8
HPOEDDCO_01054 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPOEDDCO_01055 1.9e-181 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPOEDDCO_01056 2.4e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
HPOEDDCO_01057 2.4e-212 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HPOEDDCO_01069 5.4e-54
HPOEDDCO_01091 3.5e-79
HPOEDDCO_01092 1.6e-32 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPOEDDCO_01093 7.6e-26 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPOEDDCO_01094 1.1e-101 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HPOEDDCO_01095 1.4e-81 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HPOEDDCO_01096 1e-130 S Protein of unknown function (DUF975)
HPOEDDCO_01097 4.1e-135 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPOEDDCO_01098 2.2e-151 yitS S EDD domain protein, DegV family
HPOEDDCO_01099 4.9e-19
HPOEDDCO_01100 0.0 tetP J elongation factor G
HPOEDDCO_01101 2.4e-159 P CorA-like Mg2+ transporter protein
HPOEDDCO_01103 2.5e-40 S Transglycosylase associated protein
HPOEDDCO_01104 3.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HPOEDDCO_01105 0.0 L Helicase C-terminal domain protein
HPOEDDCO_01106 9.4e-153 S Alpha beta hydrolase
HPOEDDCO_01107 1.8e-40
HPOEDDCO_01108 4.8e-164 K AI-2E family transporter
HPOEDDCO_01109 1.3e-230 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HPOEDDCO_01110 8.9e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPOEDDCO_01111 5.1e-99 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HPOEDDCO_01112 5.3e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPOEDDCO_01113 0.0 S domain, Protein
HPOEDDCO_01114 0.0 infB UW LPXTG-motif cell wall anchor domain protein
HPOEDDCO_01115 0.0 3.1.31.1 M domain protein
HPOEDDCO_01116 6.4e-260 E amino acid
HPOEDDCO_01117 3.1e-167 K LysR substrate binding domain
HPOEDDCO_01118 0.0 1.3.5.4 C FAD binding domain
HPOEDDCO_01119 7.7e-239 brnQ U Component of the transport system for branched-chain amino acids
HPOEDDCO_01120 6e-126 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HPOEDDCO_01121 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HPOEDDCO_01122 9.1e-83 S Peptidase propeptide and YPEB domain
HPOEDDCO_01123 1.3e-184 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HPOEDDCO_01124 5.3e-248 yhjX_2 P Major Facilitator Superfamily
HPOEDDCO_01125 5.5e-237 yhjX_2 P Major Facilitator Superfamily
HPOEDDCO_01126 5.9e-160 arbZ I Phosphate acyltransferases
HPOEDDCO_01127 3.8e-176 arbY M Glycosyl transferase family 8
HPOEDDCO_01128 5.7e-180 arbY M Glycosyl transferase family 8
HPOEDDCO_01129 1.1e-152 arbx M Glycosyl transferase family 8
HPOEDDCO_01130 3.1e-139 arbV 2.3.1.51 I Acyl-transferase
HPOEDDCO_01133 1.2e-129 K response regulator
HPOEDDCO_01134 0.0 vicK 2.7.13.3 T Histidine kinase
HPOEDDCO_01135 3.4e-239 yycH S YycH protein
HPOEDDCO_01136 2.3e-137 yycI S YycH protein
HPOEDDCO_01137 2.4e-147 vicX 3.1.26.11 S domain protein
HPOEDDCO_01138 1.6e-182 htrA 3.4.21.107 O serine protease
HPOEDDCO_01139 4.7e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPOEDDCO_01140 1.8e-100 P Cobalt transport protein
HPOEDDCO_01141 2.6e-231 cbiO1 S ABC transporter, ATP-binding protein
HPOEDDCO_01142 3.4e-92 S ABC-type cobalt transport system, permease component
HPOEDDCO_01143 4.4e-161 K helix_turn_helix, arabinose operon control protein
HPOEDDCO_01144 1.1e-145 htpX O Belongs to the peptidase M48B family
HPOEDDCO_01145 1.1e-90 lemA S LemA family
HPOEDDCO_01146 2.4e-182 ybiR P Citrate transporter
HPOEDDCO_01147 6.2e-67 S Iron-sulphur cluster biosynthesis
HPOEDDCO_01148 1.7e-16
HPOEDDCO_01149 2e-144
HPOEDDCO_01151 9.7e-239 ydaM M Glycosyl transferase
HPOEDDCO_01152 3.5e-197 G Glycosyl hydrolases family 8
HPOEDDCO_01153 4.5e-120 yfbR S HD containing hydrolase-like enzyme
HPOEDDCO_01154 5.4e-167 L HNH nucleases
HPOEDDCO_01155 1.4e-136 glnQ E ABC transporter, ATP-binding protein
HPOEDDCO_01156 5.9e-278 glnP P ABC transporter permease
HPOEDDCO_01157 9.4e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HPOEDDCO_01158 6.3e-63 yeaO S Protein of unknown function, DUF488
HPOEDDCO_01159 6.6e-126 terC P Integral membrane protein TerC family
HPOEDDCO_01160 5.9e-94 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HPOEDDCO_01161 9.6e-132 cobB K SIR2 family
HPOEDDCO_01162 2e-80
HPOEDDCO_01163 1.1e-269 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPOEDDCO_01164 3.1e-122 yugP S Putative neutral zinc metallopeptidase
HPOEDDCO_01165 6.5e-173 S Alpha/beta hydrolase of unknown function (DUF915)
HPOEDDCO_01166 1.9e-138 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPOEDDCO_01167 1.3e-160 ypuA S Protein of unknown function (DUF1002)
HPOEDDCO_01168 1.3e-148 epsV 2.7.8.12 S glycosyl transferase family 2
HPOEDDCO_01169 1.5e-123 S Alpha/beta hydrolase family
HPOEDDCO_01170 1.2e-58
HPOEDDCO_01171 1.5e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPOEDDCO_01172 1.5e-139 S CAAX protease self-immunity
HPOEDDCO_01173 4e-35 S CAAX protease self-immunity
HPOEDDCO_01174 5.9e-239 cycA E Amino acid permease
HPOEDDCO_01175 2.4e-113 luxT K Bacterial regulatory proteins, tetR family
HPOEDDCO_01176 6.2e-138
HPOEDDCO_01177 5.5e-52 S Cysteine-rich secretory protein family
HPOEDDCO_01178 1.2e-206 S Cysteine-rich secretory protein family
HPOEDDCO_01179 4.5e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HPOEDDCO_01180 7.8e-89
HPOEDDCO_01181 2.2e-269 yjcE P Sodium proton antiporter
HPOEDDCO_01182 2.9e-183 yibE S overlaps another CDS with the same product name
HPOEDDCO_01183 9e-112 yibF S overlaps another CDS with the same product name
HPOEDDCO_01184 1.3e-151 I alpha/beta hydrolase fold
HPOEDDCO_01185 0.0 G Belongs to the glycosyl hydrolase 31 family
HPOEDDCO_01186 1.8e-125 XK27_08435 K UTRA
HPOEDDCO_01187 5.3e-212 agaS G SIS domain
HPOEDDCO_01188 2e-227 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPOEDDCO_01189 4.3e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
HPOEDDCO_01190 2.5e-140 XK27_08455 G PTS system sorbose-specific iic component
HPOEDDCO_01191 1.6e-146 manZ_1 G PTS system mannose/fructose/sorbose family IID component
HPOEDDCO_01192 9.3e-68 2.7.1.191 G PTS system fructose IIA component
HPOEDDCO_01193 3.2e-15 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_01194 2.3e-169 S zinc-ribbon domain
HPOEDDCO_01195 1.1e-162
HPOEDDCO_01196 6.3e-87 ntd 2.4.2.6 F Nucleoside
HPOEDDCO_01197 6e-97 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPOEDDCO_01198 1.6e-121 XK27_08440 K UTRA domain
HPOEDDCO_01199 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HPOEDDCO_01200 9.4e-86 uspA T universal stress protein
HPOEDDCO_01202 8.3e-168 phnD P Phosphonate ABC transporter
HPOEDDCO_01203 3.6e-140 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HPOEDDCO_01204 1.6e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HPOEDDCO_01205 2.7e-146 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HPOEDDCO_01206 7.3e-83
HPOEDDCO_01207 3.4e-274 S Calcineurin-like phosphoesterase
HPOEDDCO_01208 0.0 asnB 6.3.5.4 E Asparagine synthase
HPOEDDCO_01209 2.3e-264 yxbA 6.3.1.12 S ATP-grasp enzyme
HPOEDDCO_01210 2.8e-64
HPOEDDCO_01211 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HPOEDDCO_01212 6.9e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPOEDDCO_01213 5.1e-102 S Iron-sulfur cluster assembly protein
HPOEDDCO_01214 3.5e-219 XK27_04775 S PAS domain
HPOEDDCO_01215 0.0 UW LPXTG-motif cell wall anchor domain protein
HPOEDDCO_01216 0.0 UW LPXTG-motif cell wall anchor domain protein
HPOEDDCO_01217 5.1e-226 yttB EGP Major facilitator Superfamily
HPOEDDCO_01218 7.2e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HPOEDDCO_01219 2.7e-152 D nuclear chromosome segregation
HPOEDDCO_01220 6.4e-134 rpl K Helix-turn-helix domain, rpiR family
HPOEDDCO_01221 1.4e-159 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
HPOEDDCO_01222 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPOEDDCO_01223 0.0 pepO 3.4.24.71 O Peptidase family M13
HPOEDDCO_01224 0.0 S Bacterial membrane protein, YfhO
HPOEDDCO_01225 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HPOEDDCO_01226 0.0 kup P Transport of potassium into the cell
HPOEDDCO_01227 0.0 kup P Transport of potassium into the cell
HPOEDDCO_01228 8.6e-72
HPOEDDCO_01229 1.2e-98
HPOEDDCO_01230 9.4e-27
HPOEDDCO_01231 1.4e-34 S Protein of unknown function (DUF2922)
HPOEDDCO_01232 1.3e-223 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPOEDDCO_01233 3.9e-238 lysA2 M Glycosyl hydrolases family 25
HPOEDDCO_01234 2.5e-144 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
HPOEDDCO_01235 0.0 yjbQ P TrkA C-terminal domain protein
HPOEDDCO_01236 9.2e-170 S Oxidoreductase family, NAD-binding Rossmann fold
HPOEDDCO_01237 4e-123
HPOEDDCO_01238 3.8e-140
HPOEDDCO_01239 1.2e-73 S PAS domain
HPOEDDCO_01240 3.8e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPOEDDCO_01241 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPOEDDCO_01242 2.4e-69 2.4.1.83 GT2 S GtrA-like protein
HPOEDDCO_01243 8e-179 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HPOEDDCO_01244 1.4e-114
HPOEDDCO_01245 1.3e-151 glcU U sugar transport
HPOEDDCO_01246 4.8e-165 yqhA G Aldose 1-epimerase
HPOEDDCO_01247 1.1e-190 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPOEDDCO_01248 6.9e-110 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPOEDDCO_01249 0.0 XK27_08315 M Sulfatase
HPOEDDCO_01250 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPOEDDCO_01252 1.9e-250 pepC 3.4.22.40 E aminopeptidase
HPOEDDCO_01253 1.2e-117 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPOEDDCO_01254 1.6e-40 ps301 K sequence-specific DNA binding
HPOEDDCO_01255 4.8e-254 pepC 3.4.22.40 E aminopeptidase
HPOEDDCO_01256 2.8e-34
HPOEDDCO_01257 1.3e-76 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPOEDDCO_01258 3.3e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HPOEDDCO_01259 1.3e-292 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPOEDDCO_01260 2.3e-79
HPOEDDCO_01261 5.3e-248 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPOEDDCO_01262 7.7e-126 yydK K UTRA
HPOEDDCO_01263 8.9e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPOEDDCO_01264 3.5e-129 gmuR K UTRA
HPOEDDCO_01265 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HPOEDDCO_01266 8.2e-38
HPOEDDCO_01267 3.4e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HPOEDDCO_01268 2.1e-266 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPOEDDCO_01269 5.7e-274 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPOEDDCO_01270 1.1e-150 ypbG 2.7.1.2 GK ROK family
HPOEDDCO_01271 8.1e-109
HPOEDDCO_01273 2.2e-108 E Belongs to the SOS response-associated peptidase family
HPOEDDCO_01274 2.2e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPOEDDCO_01275 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
HPOEDDCO_01276 3.7e-97 S TPM domain
HPOEDDCO_01277 4.2e-93 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HPOEDDCO_01278 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPOEDDCO_01279 5e-142 tatD L hydrolase, TatD family
HPOEDDCO_01280 3.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HPOEDDCO_01281 2.7e-152 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPOEDDCO_01282 7.4e-36 veg S Biofilm formation stimulator VEG
HPOEDDCO_01283 1.7e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HPOEDDCO_01284 2.5e-213 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPOEDDCO_01285 1.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPOEDDCO_01286 1.1e-175 yvdE K helix_turn _helix lactose operon repressor
HPOEDDCO_01287 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HPOEDDCO_01288 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HPOEDDCO_01289 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HPOEDDCO_01290 2.1e-112 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HPOEDDCO_01291 3.6e-210 msmX P Belongs to the ABC transporter superfamily
HPOEDDCO_01292 1.4e-228 malE G Bacterial extracellular solute-binding protein
HPOEDDCO_01293 7.2e-253 malF P Binding-protein-dependent transport system inner membrane component
HPOEDDCO_01294 1.3e-154 malG P ABC transporter permease
HPOEDDCO_01295 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HPOEDDCO_01296 3.7e-265 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPOEDDCO_01297 1.9e-71 S Domain of unknown function (DUF1934)
HPOEDDCO_01298 1.3e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HPOEDDCO_01299 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPOEDDCO_01300 7.2e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPOEDDCO_01301 2.2e-128 V ABC-type multidrug transport system, ATPase and permease components
HPOEDDCO_01302 7.3e-234 pbuX F xanthine permease
HPOEDDCO_01303 4.9e-102 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPOEDDCO_01304 2e-130 K DNA-binding helix-turn-helix protein
HPOEDDCO_01305 1.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HPOEDDCO_01306 1.7e-174 K Helix-turn-helix
HPOEDDCO_01307 5.8e-34
HPOEDDCO_01308 4e-66 doc S Fic/DOC family
HPOEDDCO_01310 2.2e-34
HPOEDDCO_01311 1.2e-78 2.5.1.74 H UbiA prenyltransferase family
HPOEDDCO_01312 3.1e-84 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HPOEDDCO_01313 2.6e-94
HPOEDDCO_01314 6.5e-270 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HPOEDDCO_01315 1.6e-227 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HPOEDDCO_01316 2.2e-54 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HPOEDDCO_01317 7.3e-185 yfdV S Membrane transport protein
HPOEDDCO_01318 4e-30
HPOEDDCO_01319 4e-53 S Putative adhesin
HPOEDDCO_01320 1.3e-68
HPOEDDCO_01322 5.3e-275 pipD E Dipeptidase
HPOEDDCO_01323 4.3e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPOEDDCO_01324 0.0 rafA 3.2.1.22 G alpha-galactosidase
HPOEDDCO_01325 7e-173 ABC-SBP S ABC transporter
HPOEDDCO_01326 2.4e-140 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HPOEDDCO_01327 5.5e-133 XK27_08845 S ABC transporter, ATP-binding protein
HPOEDDCO_01328 4.2e-284 ybeC E amino acid
HPOEDDCO_01329 8e-41 rpmE2 J Ribosomal protein L31
HPOEDDCO_01330 9.4e-261 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPOEDDCO_01331 1.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HPOEDDCO_01332 5.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPOEDDCO_01333 2.3e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPOEDDCO_01334 2.4e-124 S (CBS) domain
HPOEDDCO_01335 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPOEDDCO_01336 2.5e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPOEDDCO_01337 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPOEDDCO_01338 3.2e-34 yabO J S4 domain protein
HPOEDDCO_01339 2.3e-60 divIC D Septum formation initiator
HPOEDDCO_01340 2.3e-57 yabR J S1 RNA binding domain
HPOEDDCO_01341 2.1e-230 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPOEDDCO_01342 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPOEDDCO_01343 0.0 S membrane
HPOEDDCO_01344 1.1e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HPOEDDCO_01345 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPOEDDCO_01346 7e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HPOEDDCO_01347 1.6e-08
HPOEDDCO_01349 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPOEDDCO_01350 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPOEDDCO_01351 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPOEDDCO_01352 3.7e-101 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HPOEDDCO_01353 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPOEDDCO_01354 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPOEDDCO_01355 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPOEDDCO_01356 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HPOEDDCO_01357 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPOEDDCO_01358 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HPOEDDCO_01359 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPOEDDCO_01360 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPOEDDCO_01361 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPOEDDCO_01362 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPOEDDCO_01363 3.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPOEDDCO_01364 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPOEDDCO_01365 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HPOEDDCO_01366 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPOEDDCO_01367 7.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPOEDDCO_01368 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPOEDDCO_01369 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPOEDDCO_01370 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPOEDDCO_01371 2.7e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPOEDDCO_01372 1.1e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPOEDDCO_01373 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPOEDDCO_01374 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPOEDDCO_01375 1.4e-23 rpmD J Ribosomal protein L30
HPOEDDCO_01376 1.3e-70 rplO J Binds to the 23S rRNA
HPOEDDCO_01377 5.8e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPOEDDCO_01378 5.9e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPOEDDCO_01379 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPOEDDCO_01380 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HPOEDDCO_01381 4.6e-55 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPOEDDCO_01382 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPOEDDCO_01383 1.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPOEDDCO_01384 7.4e-62 rplQ J Ribosomal protein L17
HPOEDDCO_01385 5.9e-144 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPOEDDCO_01386 1.1e-150 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPOEDDCO_01387 3.5e-138 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPOEDDCO_01388 1.3e-148 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPOEDDCO_01389 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPOEDDCO_01390 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HPOEDDCO_01391 1.7e-151 1.6.5.2 GM NmrA-like family
HPOEDDCO_01392 5.5e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HPOEDDCO_01393 9e-127 pgm3 G Belongs to the phosphoglycerate mutase family
HPOEDDCO_01394 1.7e-51 K Transcriptional regulator, ArsR family
HPOEDDCO_01395 2.5e-153 czcD P cation diffusion facilitator family transporter
HPOEDDCO_01396 1.3e-41
HPOEDDCO_01397 2e-25
HPOEDDCO_01398 1.5e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPOEDDCO_01399 6.4e-184 S AAA domain
HPOEDDCO_01400 7.4e-250 pepC 3.4.22.40 E Peptidase C1-like family
HPOEDDCO_01401 1.5e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HPOEDDCO_01402 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPOEDDCO_01403 1.2e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPOEDDCO_01404 3.2e-264 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPOEDDCO_01405 3.9e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HPOEDDCO_01406 2.3e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPOEDDCO_01407 6.4e-146 lacT K PRD domain
HPOEDDCO_01408 3.7e-55 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HPOEDDCO_01409 4.1e-290 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HPOEDDCO_01410 3.1e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HPOEDDCO_01411 1.2e-97 yvrI K sigma factor activity
HPOEDDCO_01412 1.7e-34
HPOEDDCO_01413 6.1e-261 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HPOEDDCO_01414 3.6e-45 K helix_turn_helix, arabinose operon control protein
HPOEDDCO_01415 3.2e-130 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPOEDDCO_01416 3.3e-279 bglX 3.2.1.21 GH3 G hydrolase, family 3
HPOEDDCO_01417 1.2e-195 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HPOEDDCO_01418 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPOEDDCO_01419 9.3e-223 G Major Facilitator Superfamily
HPOEDDCO_01420 4.3e-186 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPOEDDCO_01422 5.1e-45 S CAAX protease self-immunity
HPOEDDCO_01423 1.3e-17 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HPOEDDCO_01424 9.1e-12 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPOEDDCO_01425 2.2e-99 nusG K Participates in transcription elongation, termination and antitermination
HPOEDDCO_01426 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPOEDDCO_01427 1.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPOEDDCO_01428 4.6e-109 glnP P ABC transporter permease
HPOEDDCO_01429 2e-112 glnQ 3.6.3.21 E ABC transporter
HPOEDDCO_01430 4.6e-132 aatB ET ABC transporter substrate-binding protein
HPOEDDCO_01431 8.9e-96 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPOEDDCO_01432 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPOEDDCO_01433 2.5e-145 kcsA P Ion transport protein
HPOEDDCO_01434 2.7e-32
HPOEDDCO_01435 3.7e-108 rsmC 2.1.1.172 J Methyltransferase
HPOEDDCO_01436 1.9e-23
HPOEDDCO_01437 1e-78 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPOEDDCO_01438 1.4e-307 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPOEDDCO_01439 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HPOEDDCO_01440 4e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPOEDDCO_01441 2.4e-26 S Protein of unknown function (DUF2508)
HPOEDDCO_01442 1.2e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPOEDDCO_01443 1e-51 yaaQ S Cyclic-di-AMP receptor
HPOEDDCO_01444 2.9e-151 holB 2.7.7.7 L DNA polymerase III
HPOEDDCO_01445 4.9e-57 yabA L Involved in initiation control of chromosome replication
HPOEDDCO_01446 8.2e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPOEDDCO_01447 5.1e-128 fat 3.1.2.21 I Acyl-ACP thioesterase
HPOEDDCO_01448 4.4e-86 folT S ECF transporter, substrate-specific component
HPOEDDCO_01449 5.6e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HPOEDDCO_01450 3e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HPOEDDCO_01451 6.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPOEDDCO_01452 3.6e-106
HPOEDDCO_01453 4.6e-222 clcA P chloride
HPOEDDCO_01454 4.3e-46
HPOEDDCO_01455 9.8e-97 S Protein of unknown function (DUF3990)
HPOEDDCO_01456 2e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPOEDDCO_01457 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPOEDDCO_01458 1.7e-243 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPOEDDCO_01459 1.2e-74 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
HPOEDDCO_01460 1.2e-48 L bacterial-type proximal promoter sequence-specific DNA binding
HPOEDDCO_01461 1.5e-32 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HPOEDDCO_01462 3.4e-230 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HPOEDDCO_01463 4e-150 K Helix-turn-helix XRE-family like proteins
HPOEDDCO_01466 2.4e-67
HPOEDDCO_01467 4.1e-302 uup S ABC transporter, ATP-binding protein
HPOEDDCO_01468 1.9e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HPOEDDCO_01469 1.2e-100 yvdD 3.2.2.10 S Belongs to the LOG family
HPOEDDCO_01470 3e-78 XK27_02470 K LytTr DNA-binding domain
HPOEDDCO_01471 2.5e-122 liaI S membrane
HPOEDDCO_01472 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPOEDDCO_01473 3.1e-295 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPOEDDCO_01474 4e-269 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
HPOEDDCO_01475 0.0 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
HPOEDDCO_01476 0.0 nisT V ABC transporter
HPOEDDCO_01477 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPOEDDCO_01478 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPOEDDCO_01479 1.1e-98 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPOEDDCO_01480 2e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPOEDDCO_01481 3.8e-30 yajC U Preprotein translocase
HPOEDDCO_01482 3e-281 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPOEDDCO_01483 3.3e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPOEDDCO_01484 1.6e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HPOEDDCO_01485 9.1e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HPOEDDCO_01486 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPOEDDCO_01487 2.6e-42 yrzL S Belongs to the UPF0297 family
HPOEDDCO_01488 2.3e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPOEDDCO_01489 1.2e-49 yrzB S Belongs to the UPF0473 family
HPOEDDCO_01490 1.4e-90 cvpA S Colicin V production protein
HPOEDDCO_01491 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPOEDDCO_01492 1.1e-52 trxA O Belongs to the thioredoxin family
HPOEDDCO_01493 2.4e-68 yslB S Protein of unknown function (DUF2507)
HPOEDDCO_01494 2.4e-139 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HPOEDDCO_01495 4.6e-114 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPOEDDCO_01496 9.4e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPOEDDCO_01497 2e-155 ykuT M mechanosensitive ion channel
HPOEDDCO_01498 7.4e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HPOEDDCO_01499 4e-51
HPOEDDCO_01500 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HPOEDDCO_01501 3.9e-171 ccpA K catabolite control protein A
HPOEDDCO_01502 2.2e-288 V ABC transporter transmembrane region
HPOEDDCO_01503 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HPOEDDCO_01504 3.2e-272 pepV 3.5.1.18 E dipeptidase PepV
HPOEDDCO_01505 3.5e-263 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HPOEDDCO_01506 2e-55
HPOEDDCO_01507 1.4e-192 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HPOEDDCO_01508 1.4e-53 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HPOEDDCO_01509 3.8e-96 yutD S Protein of unknown function (DUF1027)
HPOEDDCO_01510 3.1e-147 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HPOEDDCO_01511 1.5e-101 S Protein of unknown function (DUF1461)
HPOEDDCO_01512 1.4e-116 dedA S SNARE-like domain protein
HPOEDDCO_01513 2e-172 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HPOEDDCO_01514 5e-60 yugI 5.3.1.9 J general stress protein
HPOEDDCO_01515 2.4e-113 ywnB S NAD(P)H-binding
HPOEDDCO_01516 1.9e-201 S Sterol carrier protein domain
HPOEDDCO_01518 2.5e-175 S Aldo keto reductase
HPOEDDCO_01519 8.7e-66 S Protein of unknown function (DUF3278)
HPOEDDCO_01520 7.1e-29 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HPOEDDCO_01521 1.2e-109 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HPOEDDCO_01523 2.8e-115 yhiD S MgtC family
HPOEDDCO_01524 0.0
HPOEDDCO_01525 6.5e-215 I Protein of unknown function (DUF2974)
HPOEDDCO_01526 2.1e-168 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HPOEDDCO_01527 3.3e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HPOEDDCO_01528 1.2e-74 rplI J Binds to the 23S rRNA
HPOEDDCO_01529 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HPOEDDCO_01530 5.5e-156 corA P CorA-like Mg2+ transporter protein
HPOEDDCO_01531 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPOEDDCO_01532 5.1e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPOEDDCO_01533 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HPOEDDCO_01534 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPOEDDCO_01535 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPOEDDCO_01536 3.3e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPOEDDCO_01537 3.9e-19 yaaA S S4 domain
HPOEDDCO_01538 1.1e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPOEDDCO_01539 1.4e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPOEDDCO_01540 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HPOEDDCO_01541 1.7e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPOEDDCO_01542 1.8e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPOEDDCO_01543 2.9e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPOEDDCO_01544 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPOEDDCO_01545 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPOEDDCO_01546 4.3e-269 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPOEDDCO_01547 4.8e-282 clcA P chloride
HPOEDDCO_01548 7e-106 pncA Q Isochorismatase family
HPOEDDCO_01549 7.5e-196 EGP Major facilitator Superfamily
HPOEDDCO_01550 1.5e-74 ropB K Transcriptional regulator
HPOEDDCO_01551 9.5e-65 ropB K Transcriptional regulator
HPOEDDCO_01552 9.3e-106
HPOEDDCO_01553 2.6e-115 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HPOEDDCO_01554 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPOEDDCO_01555 9.3e-68 S Iron-sulphur cluster biosynthesis
HPOEDDCO_01556 2.7e-236 EGP Sugar (and other) transporter
HPOEDDCO_01557 1.4e-69 K Acetyltransferase (GNAT) domain
HPOEDDCO_01558 1.5e-244 ynbB 4.4.1.1 P aluminum resistance
HPOEDDCO_01559 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HPOEDDCO_01560 4.1e-286 E Amino acid permease
HPOEDDCO_01561 0.0 pepO 3.4.24.71 O Peptidase family M13
HPOEDDCO_01562 3.6e-141 ropB K Helix-turn-helix XRE-family like proteins
HPOEDDCO_01563 0.0 copA 3.6.3.54 P P-type ATPase
HPOEDDCO_01564 2.1e-45 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HPOEDDCO_01565 4.3e-62 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HPOEDDCO_01566 4.4e-71 atkY K Penicillinase repressor
HPOEDDCO_01567 3.5e-89
HPOEDDCO_01568 2.6e-89
HPOEDDCO_01569 3.8e-64 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPOEDDCO_01570 6.8e-227 pbuG S permease
HPOEDDCO_01571 5.8e-46 I bis(5'-adenosyl)-triphosphatase activity
HPOEDDCO_01572 3e-232 pbuG S permease
HPOEDDCO_01573 1e-85 K helix_turn_helix, mercury resistance
HPOEDDCO_01575 3e-232 pbuG S permease
HPOEDDCO_01576 2e-233 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HPOEDDCO_01577 1.8e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HPOEDDCO_01578 3.8e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HPOEDDCO_01579 3.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPOEDDCO_01580 3e-156 yeaE S Aldo/keto reductase family
HPOEDDCO_01582 1.7e-69 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_01583 4.9e-152 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
HPOEDDCO_01584 1.7e-92 agaC G PTS system sorbose-specific iic component
HPOEDDCO_01585 3.2e-123 G PTS system mannose/fructose/sorbose family IID component
HPOEDDCO_01586 2.2e-27 G PTS system fructose IIA component
HPOEDDCO_01587 1.8e-131 S membrane transporter protein
HPOEDDCO_01588 6.4e-149 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPOEDDCO_01589 3.6e-118 3.5.2.6 V Beta-lactamase enzyme family
HPOEDDCO_01590 7.4e-189 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HPOEDDCO_01591 3.7e-140 S Putative esterase
HPOEDDCO_01592 4.2e-211 S Bacterial protein of unknown function (DUF871)
HPOEDDCO_01593 1.3e-149 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HPOEDDCO_01594 3.6e-258 pts29C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPOEDDCO_01595 4.2e-181 blaA6 V Beta-lactamase
HPOEDDCO_01596 2.4e-172 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
HPOEDDCO_01597 1.1e-187 tcsA S ABC transporter substrate-binding protein PnrA-like
HPOEDDCO_01598 6.4e-168 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HPOEDDCO_01599 3.5e-241 G Bacterial extracellular solute-binding protein
HPOEDDCO_01603 7.7e-174 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HPOEDDCO_01604 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HPOEDDCO_01605 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HPOEDDCO_01606 2.1e-180 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HPOEDDCO_01607 6.6e-270 cydA 1.10.3.14 C ubiquinol oxidase
HPOEDDCO_01608 0.0 macB_3 V ABC transporter, ATP-binding protein
HPOEDDCO_01609 2.7e-189 S DUF218 domain
HPOEDDCO_01610 2.2e-103 S CAAX protease self-immunity
HPOEDDCO_01611 6.5e-90 S Protein of unknown function (DUF1440)
HPOEDDCO_01612 1.7e-255 G PTS system Galactitol-specific IIC component
HPOEDDCO_01613 2e-232 G PTS system sugar-specific permease component
HPOEDDCO_01614 2.9e-114 S Protein of unknown function (DUF969)
HPOEDDCO_01615 2.9e-157 S Protein of unknown function (DUF979)
HPOEDDCO_01616 7.9e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HPOEDDCO_01617 3.6e-30
HPOEDDCO_01618 5.6e-131 ropB K Transcriptional regulator
HPOEDDCO_01619 1.2e-157 mutR K Helix-turn-helix XRE-family like proteins
HPOEDDCO_01620 4.1e-268 V ABC transporter transmembrane region
HPOEDDCO_01621 9.3e-49 S Putative adhesin
HPOEDDCO_01622 2.5e-198 napA P Sodium/hydrogen exchanger family
HPOEDDCO_01623 0.0 cadA P P-type ATPase
HPOEDDCO_01624 1.6e-82 ykuL S (CBS) domain
HPOEDDCO_01626 3.1e-196 ywhK S Membrane
HPOEDDCO_01627 1.4e-44
HPOEDDCO_01629 2.3e-284 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPOEDDCO_01630 1.4e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HPOEDDCO_01631 3.9e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPOEDDCO_01632 9.3e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HPOEDDCO_01633 2.5e-172 pbpX2 V Beta-lactamase
HPOEDDCO_01634 1.7e-213 lmrP E Major Facilitator Superfamily
HPOEDDCO_01635 2.1e-38
HPOEDDCO_01636 2.8e-241 pts13C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPOEDDCO_01637 1.1e-156 S Alpha/beta hydrolase of unknown function (DUF915)
HPOEDDCO_01638 0.0 clpE2 O AAA domain (Cdc48 subfamily)
HPOEDDCO_01639 3e-246 yfnA E Amino Acid
HPOEDDCO_01640 8.1e-96 M NlpC P60 family protein
HPOEDDCO_01641 2.7e-97 gmk2 2.7.4.8 F Guanylate kinase
HPOEDDCO_01642 9e-44
HPOEDDCO_01643 2.3e-263 S O-antigen ligase like membrane protein
HPOEDDCO_01644 5e-108
HPOEDDCO_01645 5.5e-80 nrdI F NrdI Flavodoxin like
HPOEDDCO_01646 7.4e-172 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPOEDDCO_01647 5.5e-78
HPOEDDCO_01648 6.8e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPOEDDCO_01649 1.8e-40
HPOEDDCO_01650 9.6e-80 S Threonine/Serine exporter, ThrE
HPOEDDCO_01651 2.9e-137 thrE S Putative threonine/serine exporter
HPOEDDCO_01652 1.5e-283 S ABC transporter, ATP-binding protein
HPOEDDCO_01653 6e-59
HPOEDDCO_01654 4.4e-37
HPOEDDCO_01655 4.8e-210 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPOEDDCO_01656 0.0 pepF E oligoendopeptidase F
HPOEDDCO_01657 4.5e-61 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_01659 7.5e-251 lctP C L-lactate permease
HPOEDDCO_01660 2.2e-129 znuB U ABC 3 transport family
HPOEDDCO_01661 4.4e-115 fhuC P ABC transporter
HPOEDDCO_01662 2.6e-150 psaA P Belongs to the bacterial solute-binding protein 9 family
HPOEDDCO_01663 1.6e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPOEDDCO_01664 5.4e-136 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HPOEDDCO_01665 0.0 M domain protein
HPOEDDCO_01666 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HPOEDDCO_01667 1e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HPOEDDCO_01668 8.4e-134 fruR K DeoR C terminal sensor domain
HPOEDDCO_01669 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HPOEDDCO_01670 1.2e-203 natB CP ABC-2 family transporter protein
HPOEDDCO_01671 2.8e-160 natA S ABC transporter, ATP-binding protein
HPOEDDCO_01672 4.4e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HPOEDDCO_01673 1.1e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPOEDDCO_01674 2.4e-201 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HPOEDDCO_01675 7.4e-121 K response regulator
HPOEDDCO_01676 0.0 V ABC transporter
HPOEDDCO_01677 3.7e-294 V ABC transporter, ATP-binding protein
HPOEDDCO_01678 8.9e-137 XK27_01040 S Protein of unknown function (DUF1129)
HPOEDDCO_01679 5.7e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPOEDDCO_01680 1.1e-42 yyzM S Bacterial protein of unknown function (DUF951)
HPOEDDCO_01681 7.2e-153 spo0J K Belongs to the ParB family
HPOEDDCO_01682 3.3e-138 soj D Sporulation initiation inhibitor
HPOEDDCO_01683 1.4e-140 noc K Belongs to the ParB family
HPOEDDCO_01684 1.4e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HPOEDDCO_01685 5.4e-95 cvpA S Colicin V production protein
HPOEDDCO_01686 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPOEDDCO_01687 4.5e-146 3.1.3.48 T Tyrosine phosphatase family
HPOEDDCO_01688 1.3e-193 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HPOEDDCO_01689 7.1e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
HPOEDDCO_01690 1.5e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HPOEDDCO_01691 2.9e-108 K WHG domain
HPOEDDCO_01692 8e-38
HPOEDDCO_01693 3.9e-268 pipD E Dipeptidase
HPOEDDCO_01694 1.2e-293 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPOEDDCO_01695 3.3e-296 2.7.1.211 G phosphotransferase system
HPOEDDCO_01696 1.2e-157 K CAT RNA binding domain
HPOEDDCO_01697 2.1e-112 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HPOEDDCO_01698 5.9e-170 hrtB V ABC transporter permease
HPOEDDCO_01699 1.1e-89 ygfC K Bacterial regulatory proteins, tetR family
HPOEDDCO_01700 1.5e-106 G phosphoglycerate mutase
HPOEDDCO_01701 1.7e-111 G Phosphoglycerate mutase family
HPOEDDCO_01702 4e-136 aroD S Alpha/beta hydrolase family
HPOEDDCO_01703 6.7e-102 S Protein of unknown function (DUF975)
HPOEDDCO_01704 3.1e-128 S Belongs to the UPF0246 family
HPOEDDCO_01705 2.2e-52
HPOEDDCO_01706 5.5e-124
HPOEDDCO_01707 9.2e-156 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HPOEDDCO_01708 6e-308 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HPOEDDCO_01709 1.9e-138 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
HPOEDDCO_01710 6.3e-154 ybbH_2 K Helix-turn-helix domain, rpiR family
HPOEDDCO_01711 9.5e-166 2.7.7.12 C Domain of unknown function (DUF4931)
HPOEDDCO_01712 4.5e-52 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
HPOEDDCO_01713 5.8e-155
HPOEDDCO_01714 2.8e-224 mdtG EGP Major facilitator Superfamily
HPOEDDCO_01715 5.1e-122 puuD S peptidase C26
HPOEDDCO_01716 1.3e-290 V ABC transporter transmembrane region
HPOEDDCO_01717 2.5e-89 ymdB S Macro domain protein
HPOEDDCO_01718 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HPOEDDCO_01719 4.4e-288 scrB 3.2.1.26 GH32 G invertase
HPOEDDCO_01720 1e-184 scrR K Transcriptional regulator, LacI family
HPOEDDCO_01721 7e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
HPOEDDCO_01722 2.7e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HPOEDDCO_01723 2.5e-129 cobQ S glutamine amidotransferase
HPOEDDCO_01724 1.7e-254 yfnA E Amino Acid
HPOEDDCO_01725 5.9e-163 EG EamA-like transporter family
HPOEDDCO_01726 4e-192 asnA 6.3.1.1 F aspartate--ammonia ligase
HPOEDDCO_01727 7.2e-204 S CAAX protease self-immunity
HPOEDDCO_01728 1.4e-235 steT_1 E amino acid
HPOEDDCO_01729 2.8e-134 puuD S peptidase C26
HPOEDDCO_01730 9e-219 yifK E Amino acid permease
HPOEDDCO_01731 9e-251 yifK E Amino acid permease
HPOEDDCO_01732 1.8e-65 manO S Domain of unknown function (DUF956)
HPOEDDCO_01733 5.6e-172 manN G system, mannose fructose sorbose family IID component
HPOEDDCO_01734 1.7e-124 manY G PTS system
HPOEDDCO_01735 2.3e-184 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HPOEDDCO_01737 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
HPOEDDCO_01739 6.7e-116 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HPOEDDCO_01740 0.0 helD 3.6.4.12 L DNA helicase
HPOEDDCO_01742 4.1e-130 yvpB S Peptidase_C39 like family
HPOEDDCO_01743 2.3e-122 K Helix-turn-helix domain, rpiR family
HPOEDDCO_01744 3.8e-82 rarA L MgsA AAA+ ATPase C terminal
HPOEDDCO_01745 5e-243 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPOEDDCO_01746 1.5e-103 E GDSL-like Lipase/Acylhydrolase
HPOEDDCO_01747 1.8e-161 coaA 2.7.1.33 F Pantothenic acid kinase
HPOEDDCO_01748 3.7e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPOEDDCO_01749 0.0 fhaB M Rib/alpha-like repeat
HPOEDDCO_01750 2.1e-132 licT K CAT RNA binding domain
HPOEDDCO_01751 0.0 bglP 2.7.1.211 G phosphotransferase system
HPOEDDCO_01752 7e-286 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPOEDDCO_01753 6.2e-147 EG EamA-like transporter family
HPOEDDCO_01754 5.7e-99 S PFAM Archaeal ATPase
HPOEDDCO_01755 0.0 oppA E ABC transporter substrate-binding protein
HPOEDDCO_01756 0.0 uvrA3 L excinuclease ABC, A subunit
HPOEDDCO_01757 3e-58
HPOEDDCO_01758 3e-97 UW LPXTG-motif cell wall anchor domain protein
HPOEDDCO_01759 0.0 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
HPOEDDCO_01760 1.1e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPOEDDCO_01761 2.6e-205 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HPOEDDCO_01762 9.3e-232 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPOEDDCO_01763 1.1e-127 S PAS domain
HPOEDDCO_01764 1.2e-273 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HPOEDDCO_01765 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HPOEDDCO_01766 1.5e-125 glvR K Helix-turn-helix domain, rpiR family
HPOEDDCO_01767 8.6e-58
HPOEDDCO_01768 5.9e-80 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPOEDDCO_01769 5e-23 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_01770 3.5e-149 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_01771 7.5e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPOEDDCO_01772 0.0 M domain protein
HPOEDDCO_01773 2.4e-144 pnuC H nicotinamide mononucleotide transporter
HPOEDDCO_01774 6.6e-85 S PAS domain
HPOEDDCO_01775 6.8e-237 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HPOEDDCO_01776 1.9e-72 S Protein of unknown function (DUF3290)
HPOEDDCO_01777 1.3e-111 yviA S Protein of unknown function (DUF421)
HPOEDDCO_01778 7.5e-141 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HPOEDDCO_01779 8.9e-181 dnaQ 2.7.7.7 L EXOIII
HPOEDDCO_01780 2.7e-197 ltrA S Bacterial low temperature requirement A protein (LtrA)
HPOEDDCO_01781 1e-148 dkg S reductase
HPOEDDCO_01782 7.4e-123 endA F DNA RNA non-specific endonuclease
HPOEDDCO_01783 2.5e-280 pipD E Dipeptidase
HPOEDDCO_01784 4.6e-202 malK P ATPases associated with a variety of cellular activities
HPOEDDCO_01785 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
HPOEDDCO_01786 1.5e-147 gtsC P Binding-protein-dependent transport system inner membrane component
HPOEDDCO_01787 1.6e-254 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HPOEDDCO_01788 2.2e-238 G Bacterial extracellular solute-binding protein
HPOEDDCO_01789 2.8e-42 ypaA S Protein of unknown function (DUF1304)
HPOEDDCO_01790 3e-70 yybA 2.3.1.57 K Transcriptional regulator
HPOEDDCO_01791 1.3e-82 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HPOEDDCO_01792 6.3e-73 yjcF S Acetyltransferase (GNAT) domain
HPOEDDCO_01793 1.2e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HPOEDDCO_01794 6.9e-162 3.5.2.6 V Beta-lactamase enzyme family
HPOEDDCO_01795 2e-95 yobS K Bacterial regulatory proteins, tetR family
HPOEDDCO_01796 0.0 ydgH S MMPL family
HPOEDDCO_01797 2.4e-123 cof S haloacid dehalogenase-like hydrolase
HPOEDDCO_01798 9.6e-121 S SNARE associated Golgi protein
HPOEDDCO_01799 7.6e-175
HPOEDDCO_01800 3.4e-250 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HPOEDDCO_01801 1.1e-142 hipB K Helix-turn-helix
HPOEDDCO_01802 2.1e-143 I alpha/beta hydrolase fold
HPOEDDCO_01803 1e-105 yjbF S SNARE associated Golgi protein
HPOEDDCO_01804 7.1e-98 J Acetyltransferase (GNAT) domain
HPOEDDCO_01805 5.2e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPOEDDCO_01807 1.2e-263 UW Tetratricopeptide repeat
HPOEDDCO_01809 7.2e-189 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HPOEDDCO_01810 4.1e-212 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HPOEDDCO_01811 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPOEDDCO_01812 1.6e-56 asp3 S Accessory Sec secretory system ASP3
HPOEDDCO_01813 3.4e-190 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HPOEDDCO_01814 2.7e-136 asp1 S Accessory Sec system protein Asp1
HPOEDDCO_01815 3.4e-150 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HPOEDDCO_01816 3.8e-148 S hydrolase
HPOEDDCO_01818 3.1e-167 yegS 2.7.1.107 G Lipid kinase
HPOEDDCO_01819 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPOEDDCO_01820 1.5e-264 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPOEDDCO_01821 4.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPOEDDCO_01822 8.5e-207 camS S sex pheromone
HPOEDDCO_01823 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPOEDDCO_01824 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HPOEDDCO_01825 1.1e-112 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HPOEDDCO_01826 1.3e-100 S ECF transporter, substrate-specific component
HPOEDDCO_01828 4.5e-82 ydcK S Belongs to the SprT family
HPOEDDCO_01829 3.4e-129 M Glycosyltransferase sugar-binding region containing DXD motif
HPOEDDCO_01830 5.3e-254 epsU S Polysaccharide biosynthesis protein
HPOEDDCO_01831 2.3e-215 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPOEDDCO_01832 3.9e-145
HPOEDDCO_01833 6.7e-287 V ABC transporter transmembrane region
HPOEDDCO_01834 0.0 pacL 3.6.3.8 P P-type ATPase
HPOEDDCO_01835 1.9e-139 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HPOEDDCO_01836 7.2e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPOEDDCO_01837 0.0 tuaG GT2 M Glycosyltransferase like family 2
HPOEDDCO_01838 2.2e-196 csaB M Glycosyl transferases group 1
HPOEDDCO_01839 1.3e-128 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HPOEDDCO_01840 1.5e-67 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HPOEDDCO_01841 3.6e-123 gntR1 K UTRA
HPOEDDCO_01842 1.2e-184
HPOEDDCO_01843 3.9e-50 P Rhodanese Homology Domain
HPOEDDCO_01846 1.9e-161 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HPOEDDCO_01847 8.4e-127 K SIS domain
HPOEDDCO_01848 7e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HPOEDDCO_01849 9.2e-71 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HPOEDDCO_01850 1e-102 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HPOEDDCO_01851 2.1e-57 yjgN S Bacterial protein of unknown function (DUF898)
HPOEDDCO_01853 2e-86 M LysM domain protein
HPOEDDCO_01854 1.8e-107 M LysM domain protein
HPOEDDCO_01855 1.2e-116 S Putative ABC-transporter type IV
HPOEDDCO_01856 1.3e-48 psiE S Phosphate-starvation-inducible E
HPOEDDCO_01857 1.3e-74 K acetyltransferase
HPOEDDCO_01858 3.1e-128 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HPOEDDCO_01860 4.8e-154 yvgN C Aldo keto reductase
HPOEDDCO_01861 1e-243 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HPOEDDCO_01862 2.2e-173 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPOEDDCO_01863 2.2e-214 V ABC transporter (Permease)
HPOEDDCO_01864 2.9e-85 V ABC transporter, ATP-binding protein
HPOEDDCO_01865 2.5e-24 slyA K helix_turn_helix multiple antibiotic resistance protein
HPOEDDCO_01867 2.3e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
HPOEDDCO_01868 6.2e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPOEDDCO_01869 5e-104 pncA Q Isochorismatase family
HPOEDDCO_01870 2.2e-27
HPOEDDCO_01871 8.8e-75 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HPOEDDCO_01872 7e-91 2.7.7.65 T phosphorelay sensor kinase activity
HPOEDDCO_01873 9.7e-133 cbiQ P Cobalt transport protein
HPOEDDCO_01874 7.8e-157 P ABC transporter
HPOEDDCO_01875 1.7e-148 cbiO2 P ABC transporter
HPOEDDCO_01876 6.5e-102 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HPOEDDCO_01877 2.5e-77
HPOEDDCO_01878 3.6e-100
HPOEDDCO_01879 1.4e-39 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HPOEDDCO_01880 3.6e-29 relB L RelB antitoxin
HPOEDDCO_01881 4.3e-133 D CobQ CobB MinD ParA nucleotide binding domain protein
HPOEDDCO_01883 7.5e-159 repA S Replication initiator protein A
HPOEDDCO_01884 1.2e-40 relB L Addiction module antitoxin, RelB DinJ family
HPOEDDCO_01885 1.1e-26
HPOEDDCO_01886 2.5e-121 S protein conserved in bacteria
HPOEDDCO_01887 2.6e-40
HPOEDDCO_01888 4.2e-27
HPOEDDCO_01889 0.0 L MobA MobL family protein
HPOEDDCO_01890 4.1e-84 L Psort location Cytoplasmic, score
HPOEDDCO_01891 1.3e-93 L COG2963 Transposase and inactivated derivatives
HPOEDDCO_01892 3.8e-188 L COG2963 Transposase and inactivated derivatives
HPOEDDCO_01893 2e-183 3.4.16.4 M ErfK YbiS YcfS YnhG
HPOEDDCO_01894 3.3e-47 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPOEDDCO_01895 2.7e-138 rpiR1 K Helix-turn-helix domain, rpiR family
HPOEDDCO_01896 6.9e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HPOEDDCO_01897 0.0 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HPOEDDCO_01898 2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
HPOEDDCO_01899 2.4e-51
HPOEDDCO_01900 7.6e-24
HPOEDDCO_01901 5.3e-121 pgm3 G Phosphoglycerate mutase family
HPOEDDCO_01902 0.0 V FtsX-like permease family
HPOEDDCO_01903 7.7e-132 cysA V ABC transporter, ATP-binding protein
HPOEDDCO_01904 2.4e-278 E amino acid
HPOEDDCO_01905 4.3e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPOEDDCO_01906 1.6e-216 S Putative peptidoglycan binding domain
HPOEDDCO_01908 5.1e-230 cycA E Amino acid permease
HPOEDDCO_01909 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HPOEDDCO_01910 4.4e-57
HPOEDDCO_01911 1.2e-102 4.1.1.44 S Carboxymuconolactone decarboxylase family
HPOEDDCO_01912 0.0 S TerB-C domain
HPOEDDCO_01913 6.2e-249 P P-loop Domain of unknown function (DUF2791)
HPOEDDCO_01914 0.0 lhr L DEAD DEAH box helicase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)