ORF_ID e_value Gene_name EC_number CAZy COGs Description
CIOKFBHH_00001 6.6e-135 L Transposase and inactivated derivatives
CIOKFBHH_00002 6.2e-143 L Belongs to the 'phage' integrase family
CIOKFBHH_00012 4.3e-155 L COG2801 Transposase and inactivated derivatives
CIOKFBHH_00013 1.1e-23 L Helix-turn-helix domain
CIOKFBHH_00014 1.1e-166 L PFAM Integrase catalytic region
CIOKFBHH_00015 9.2e-21 L transposase, IS605 OrfB family
CIOKFBHH_00016 7.1e-186 L PFAM Integrase catalytic region
CIOKFBHH_00017 2.4e-142 EG EamA-like transporter family
CIOKFBHH_00018 4.7e-257 XK27_04775 S PAS domain
CIOKFBHH_00019 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
CIOKFBHH_00020 8e-54 yitW S Iron-sulfur cluster assembly protein
CIOKFBHH_00021 2.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
CIOKFBHH_00022 1e-142 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
CIOKFBHH_00023 3.9e-171 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CIOKFBHH_00024 1.3e-57 S Flavodoxin
CIOKFBHH_00025 2.2e-72 moaE 2.8.1.12 H MoaE protein
CIOKFBHH_00026 6.4e-35 moaD 2.8.1.12 H ThiS family
CIOKFBHH_00027 2.3e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CIOKFBHH_00028 8.1e-216 narK P Major Facilitator Superfamily
CIOKFBHH_00029 1.5e-58 yitW S Iron-sulfur cluster assembly protein
CIOKFBHH_00030 1e-162 hipB K Helix-turn-helix
CIOKFBHH_00031 3e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CIOKFBHH_00033 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
CIOKFBHH_00034 8.8e-184
CIOKFBHH_00035 1.2e-39
CIOKFBHH_00036 1.5e-115 nreC K PFAM regulatory protein LuxR
CIOKFBHH_00037 1.6e-183 comP 2.7.13.3 F Sensor histidine kinase
CIOKFBHH_00038 1.4e-77 nreA T GAF domain
CIOKFBHH_00039 4.2e-40
CIOKFBHH_00040 1.1e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CIOKFBHH_00041 9.3e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CIOKFBHH_00042 4.1e-231 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
CIOKFBHH_00043 1.9e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
CIOKFBHH_00044 1.4e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
CIOKFBHH_00045 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CIOKFBHH_00046 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
CIOKFBHH_00047 3.1e-102 narJ C Nitrate reductase delta subunit
CIOKFBHH_00048 1.8e-127 narI 1.7.5.1 C Nitrate reductase
CIOKFBHH_00049 4.3e-183
CIOKFBHH_00050 5.9e-76
CIOKFBHH_00051 5.3e-35 yjcE P Sodium proton antiporter
CIOKFBHH_00052 1.6e-08 yjcE P Sodium proton antiporter
CIOKFBHH_00053 5.4e-49 ywnB S NAD(P)H-binding
CIOKFBHH_00054 1.9e-291 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
CIOKFBHH_00055 2.2e-96 V VanZ like family
CIOKFBHH_00056 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CIOKFBHH_00057 9.5e-61 yneR
CIOKFBHH_00058 1.4e-181 K Transcriptional regulator, LacI family
CIOKFBHH_00059 3.2e-229 gntT EG Gluconate
CIOKFBHH_00060 3.2e-286 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
CIOKFBHH_00061 6.2e-171 mutR K Transcriptional activator, Rgg GadR MutR family
CIOKFBHH_00062 3.6e-08 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
CIOKFBHH_00063 1.6e-76 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
CIOKFBHH_00064 2.4e-192 yegU O ADP-ribosylglycohydrolase
CIOKFBHH_00065 2.3e-251 F Belongs to the purine-cytosine permease (2.A.39) family
CIOKFBHH_00066 7.2e-169 G Belongs to the carbohydrate kinase PfkB family
CIOKFBHH_00067 4.4e-129 L transposase, IS605 OrfB family
CIOKFBHH_00068 4.3e-38 M Protein of unknown function (DUF3737)
CIOKFBHH_00069 1.5e-76 yphH S Cupin domain
CIOKFBHH_00070 4.1e-21 L Transposase
CIOKFBHH_00071 1.2e-202 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
CIOKFBHH_00072 4.3e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
CIOKFBHH_00073 1.4e-52 cps3I G Acyltransferase family
CIOKFBHH_00074 4.5e-45 M biosynthesis protein
CIOKFBHH_00075 1.2e-94 cps3F
CIOKFBHH_00076 4.6e-148 cps1D M Domain of unknown function (DUF4422)
CIOKFBHH_00077 1.1e-118 rfbP M Bacterial sugar transferase
CIOKFBHH_00078 4.2e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
CIOKFBHH_00079 1.3e-07
CIOKFBHH_00080 3.8e-31 S Protein of unknown function (DUF2922)
CIOKFBHH_00081 2.7e-139 yihY S Belongs to the UPF0761 family
CIOKFBHH_00082 0.0 XK27_08315 M Sulfatase
CIOKFBHH_00083 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
CIOKFBHH_00084 8.5e-78 fld C Flavodoxin
CIOKFBHH_00085 8.6e-75 gtcA S Teichoic acid glycosylation protein
CIOKFBHH_00087 4.4e-231 yfmL 3.6.4.13 L DEAD DEAH box helicase
CIOKFBHH_00088 1.3e-190 mocA S Oxidoreductase
CIOKFBHH_00089 1.4e-62 S Domain of unknown function (DUF4828)
CIOKFBHH_00090 1.4e-104 yvdD 3.2.2.10 S Belongs to the LOG family
CIOKFBHH_00091 3.3e-161 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CIOKFBHH_00092 1.5e-288 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
CIOKFBHH_00093 4.7e-140 S NADPH-dependent FMN reductase
CIOKFBHH_00094 2.3e-33 yneR S Belongs to the HesB IscA family
CIOKFBHH_00095 1.3e-304 ybiT S ABC transporter, ATP-binding protein
CIOKFBHH_00096 2.7e-216 L transposase, IS605 OrfB family
CIOKFBHH_00097 2e-85 dps P Belongs to the Dps family
CIOKFBHH_00098 1.6e-105
CIOKFBHH_00099 1.3e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CIOKFBHH_00100 1.4e-101 K helix_turn_helix multiple antibiotic resistance protein
CIOKFBHH_00101 3.4e-49 fsr EGP Major Facilitator Superfamily
CIOKFBHH_00102 5.1e-81 fsr EGP Major Facilitator Superfamily
CIOKFBHH_00103 2.7e-99 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CIOKFBHH_00104 1.7e-102 S CAAX protease self-immunity
CIOKFBHH_00106 2.8e-120 Q Methyltransferase domain
CIOKFBHH_00107 8.6e-91 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
CIOKFBHH_00108 2.8e-51 K 2 iron, 2 sulfur cluster binding
CIOKFBHH_00109 0.0 mco Q Multicopper oxidase
CIOKFBHH_00110 7.1e-89 S Aminoacyl-tRNA editing domain
CIOKFBHH_00111 3.1e-75 ddaH 3.5.3.18 E Amidinotransferase
CIOKFBHH_00113 2e-194 nhaC C Na H antiporter NhaC
CIOKFBHH_00114 1.1e-185 S Phosphotransferase system, EIIC
CIOKFBHH_00115 4.6e-23 D mRNA cleavage
CIOKFBHH_00116 1.9e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
CIOKFBHH_00118 2.2e-22
CIOKFBHH_00119 1.4e-30 L Transposase
CIOKFBHH_00120 3.1e-19 T Antidote-toxin recognition MazE, bacterial antitoxin
CIOKFBHH_00121 9.1e-08 C Domain of unknown function (DUF4145)
CIOKFBHH_00122 2.9e-19 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIOKFBHH_00123 2e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIOKFBHH_00124 9.6e-186 yegS 2.7.1.107 G Lipid kinase
CIOKFBHH_00125 4.2e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIOKFBHH_00126 5.7e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CIOKFBHH_00127 6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CIOKFBHH_00128 1.6e-165 camS S sex pheromone
CIOKFBHH_00129 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CIOKFBHH_00130 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CIOKFBHH_00131 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CIOKFBHH_00132 5.2e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CIOKFBHH_00133 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
CIOKFBHH_00134 1.2e-138 IQ reductase
CIOKFBHH_00135 1.1e-50 S interspecies interaction between organisms
CIOKFBHH_00136 5.6e-121 S interspecies interaction between organisms
CIOKFBHH_00137 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
CIOKFBHH_00138 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CIOKFBHH_00139 2.2e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CIOKFBHH_00140 9.2e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIOKFBHH_00141 7.5e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIOKFBHH_00142 2e-149 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CIOKFBHH_00143 2.8e-61 rplQ J Ribosomal protein L17
CIOKFBHH_00144 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIOKFBHH_00145 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CIOKFBHH_00146 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CIOKFBHH_00147 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CIOKFBHH_00148 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CIOKFBHH_00149 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CIOKFBHH_00150 2.6e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CIOKFBHH_00151 2.1e-65 rplO J Binds to the 23S rRNA
CIOKFBHH_00152 2.5e-23 rpmD J Ribosomal protein L30
CIOKFBHH_00153 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CIOKFBHH_00154 5.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CIOKFBHH_00155 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CIOKFBHH_00156 3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CIOKFBHH_00157 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIOKFBHH_00158 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CIOKFBHH_00159 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CIOKFBHH_00160 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CIOKFBHH_00161 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CIOKFBHH_00162 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
CIOKFBHH_00163 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CIOKFBHH_00164 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CIOKFBHH_00165 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CIOKFBHH_00166 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CIOKFBHH_00167 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CIOKFBHH_00168 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CIOKFBHH_00169 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
CIOKFBHH_00170 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CIOKFBHH_00171 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CIOKFBHH_00172 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CIOKFBHH_00173 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CIOKFBHH_00174 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CIOKFBHH_00175 2.1e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
CIOKFBHH_00176 7.4e-214 ykiI
CIOKFBHH_00177 5.6e-135 puuD S peptidase C26
CIOKFBHH_00178 1.8e-15 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CIOKFBHH_00179 1.2e-55 L Helix-turn-helix domain
CIOKFBHH_00180 1.7e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CIOKFBHH_00181 1.3e-153 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
CIOKFBHH_00182 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CIOKFBHH_00183 1.5e-197 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CIOKFBHH_00184 1.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CIOKFBHH_00185 2.8e-137 cof S haloacid dehalogenase-like hydrolase
CIOKFBHH_00186 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CIOKFBHH_00187 1.4e-113 yfbR S HD containing hydrolase-like enzyme
CIOKFBHH_00189 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CIOKFBHH_00190 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CIOKFBHH_00191 7.6e-205
CIOKFBHH_00192 2.1e-160 rapZ S Displays ATPase and GTPase activities
CIOKFBHH_00193 1.7e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CIOKFBHH_00194 4.2e-167 whiA K May be required for sporulation
CIOKFBHH_00195 7.9e-76 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CIOKFBHH_00196 7.2e-17 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CIOKFBHH_00197 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CIOKFBHH_00201 2.2e-52 S Putative inner membrane protein (DUF1819)
CIOKFBHH_00202 1.4e-101 S Domain of unknown function (DUF1788)
CIOKFBHH_00203 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
CIOKFBHH_00204 0.0 2.1.1.72 V Eco57I restriction-modification methylase
CIOKFBHH_00205 3.6e-191 L Belongs to the 'phage' integrase family
CIOKFBHH_00206 4.4e-297 V Eco57I restriction-modification methylase
CIOKFBHH_00207 0.0 S PglZ domain
CIOKFBHH_00208 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
CIOKFBHH_00209 0.0 yfjM S Protein of unknown function DUF262
CIOKFBHH_00210 5.9e-152 glcU U sugar transport
CIOKFBHH_00211 1.3e-250 yclK 2.7.13.3 T Histidine kinase
CIOKFBHH_00212 2.8e-131 K response regulator
CIOKFBHH_00214 1.2e-57 S Domain of unknown function (DUF956)
CIOKFBHH_00215 3e-170 manN G system, mannose fructose sorbose family IID component
CIOKFBHH_00216 2.7e-122 manY G PTS system
CIOKFBHH_00217 5.3e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
CIOKFBHH_00218 2.3e-181 yfeX P Peroxidase
CIOKFBHH_00219 6.5e-90 racA K Domain of unknown function (DUF1836)
CIOKFBHH_00220 2.3e-148 yitS S EDD domain protein, DegV family
CIOKFBHH_00221 4.5e-132 manA 5.3.1.8 G mannose-6-phosphate isomerase
CIOKFBHH_00222 9.6e-169 K LysR substrate binding domain
CIOKFBHH_00223 9.2e-160 MA20_14895 S Conserved hypothetical protein 698
CIOKFBHH_00224 2.2e-68 lytE M Lysin motif
CIOKFBHH_00225 4e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
CIOKFBHH_00226 5.4e-211 oatA I Acyltransferase
CIOKFBHH_00227 3.3e-52
CIOKFBHH_00228 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CIOKFBHH_00229 1.1e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CIOKFBHH_00230 7e-116 ybbR S YbbR-like protein
CIOKFBHH_00231 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CIOKFBHH_00232 5.7e-166 murB 1.3.1.98 M Cell wall formation
CIOKFBHH_00233 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
CIOKFBHH_00234 7.3e-89 K Acetyltransferase (GNAT) domain
CIOKFBHH_00235 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
CIOKFBHH_00236 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CIOKFBHH_00237 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CIOKFBHH_00238 1.2e-108 yxjI
CIOKFBHH_00239 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CIOKFBHH_00240 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CIOKFBHH_00241 4.5e-33 secG U Preprotein translocase
CIOKFBHH_00242 3.2e-289 clcA P chloride
CIOKFBHH_00243 1.5e-253 yifK E Amino acid permease
CIOKFBHH_00244 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CIOKFBHH_00245 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIOKFBHH_00246 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CIOKFBHH_00247 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CIOKFBHH_00248 1e-15
CIOKFBHH_00249 7.9e-13
CIOKFBHH_00250 9.3e-248 EGP Major facilitator Superfamily
CIOKFBHH_00251 1.1e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CIOKFBHH_00252 6.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CIOKFBHH_00253 3.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CIOKFBHH_00254 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CIOKFBHH_00255 3.2e-50 ylxQ J ribosomal protein
CIOKFBHH_00256 1.4e-47 ylxR K Protein of unknown function (DUF448)
CIOKFBHH_00257 3.7e-224 nusA K Participates in both transcription termination and antitermination
CIOKFBHH_00258 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
CIOKFBHH_00259 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CIOKFBHH_00260 2.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CIOKFBHH_00261 1.1e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CIOKFBHH_00262 1.2e-206 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CIOKFBHH_00263 8e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
CIOKFBHH_00264 6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine
CIOKFBHH_00265 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIOKFBHH_00266 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CIOKFBHH_00267 8.5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CIOKFBHH_00268 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
CIOKFBHH_00269 1.3e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CIOKFBHH_00270 4.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CIOKFBHH_00271 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CIOKFBHH_00272 4.9e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CIOKFBHH_00273 5e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
CIOKFBHH_00274 2.3e-47 yazA L GIY-YIG catalytic domain protein
CIOKFBHH_00275 2.3e-136 yabB 2.1.1.223 L Methyltransferase small domain
CIOKFBHH_00276 2.8e-114 plsC 2.3.1.51 I Acyltransferase
CIOKFBHH_00277 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
CIOKFBHH_00278 2.4e-37 ynzC S UPF0291 protein
CIOKFBHH_00279 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CIOKFBHH_00280 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
CIOKFBHH_00281 5.6e-122 lutA C Cysteine-rich domain
CIOKFBHH_00282 4e-244 lutB C 4Fe-4S dicluster domain
CIOKFBHH_00283 4.8e-86 yrjD S LUD domain
CIOKFBHH_00284 2.2e-30 E IrrE N-terminal-like domain
CIOKFBHH_00285 2.8e-42 K transcriptional regulator
CIOKFBHH_00286 6.6e-128 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
CIOKFBHH_00287 1.7e-188 ybhR V ABC transporter
CIOKFBHH_00288 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
CIOKFBHH_00289 1.2e-286 glpQ 3.1.4.46 C phosphodiesterase
CIOKFBHH_00290 2.6e-163 yvgN C Aldo keto reductase
CIOKFBHH_00291 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CIOKFBHH_00292 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CIOKFBHH_00293 1.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIOKFBHH_00294 0.0 clpL O associated with various cellular activities
CIOKFBHH_00295 2.7e-35
CIOKFBHH_00296 6.5e-218 patA 2.6.1.1 E Aminotransferase
CIOKFBHH_00297 2e-180 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIOKFBHH_00298 1.4e-183 D Alpha beta
CIOKFBHH_00299 1.4e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CIOKFBHH_00300 8.8e-16 natA S ABC transporter, ATP-binding protein
CIOKFBHH_00301 1.8e-15 natA S ABC transporter, ATP-binding protein
CIOKFBHH_00302 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
CIOKFBHH_00303 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
CIOKFBHH_00304 6.6e-251 malT G Major Facilitator
CIOKFBHH_00305 3.2e-175 malR K Transcriptional regulator, LacI family
CIOKFBHH_00306 5.7e-71 K Transcriptional regulator
CIOKFBHH_00307 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CIOKFBHH_00308 3e-208 htrA 3.4.21.107 O serine protease
CIOKFBHH_00309 6e-154 vicX 3.1.26.11 S domain protein
CIOKFBHH_00310 2.7e-143 yycI S YycH protein
CIOKFBHH_00311 3.3e-239 yycH S YycH protein
CIOKFBHH_00312 0.0 vicK 2.7.13.3 T Histidine kinase
CIOKFBHH_00313 6.8e-130 K response regulator
CIOKFBHH_00316 0.0 FbpA K Fibronectin-binding protein
CIOKFBHH_00317 3.2e-161 degV S EDD domain protein, DegV family
CIOKFBHH_00318 4.6e-98
CIOKFBHH_00319 1.2e-132 S Belongs to the UPF0246 family
CIOKFBHH_00320 7.3e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CIOKFBHH_00321 2.6e-112 ylbE GM NAD(P)H-binding
CIOKFBHH_00322 3.5e-99 K Acetyltransferase (GNAT) domain
CIOKFBHH_00323 8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CIOKFBHH_00324 3.5e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CIOKFBHH_00325 1.9e-286 thrC 4.2.3.1 E Threonine synthase
CIOKFBHH_00326 7e-91 azlC E azaleucine resistance protein AzlC
CIOKFBHH_00327 2.8e-54 azlD E Branched-chain amino acid transport
CIOKFBHH_00328 1.6e-31 yphJ 4.1.1.44 S decarboxylase
CIOKFBHH_00329 1.1e-09 yphJ 4.1.1.44 S decarboxylase
CIOKFBHH_00330 1.4e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
CIOKFBHH_00331 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
CIOKFBHH_00332 1.4e-200 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CIOKFBHH_00333 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
CIOKFBHH_00334 1.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
CIOKFBHH_00335 6.8e-217 E GDSL-like Lipase/Acylhydrolase family
CIOKFBHH_00336 7.2e-52 K Transcriptional regulator
CIOKFBHH_00337 1.7e-15 K LysR substrate binding domain protein
CIOKFBHH_00338 1.7e-213 naiP EGP Major facilitator Superfamily
CIOKFBHH_00339 1.3e-249 yhdP S Transporter associated domain
CIOKFBHH_00340 3.4e-201 mdtG EGP Major facilitator Superfamily
CIOKFBHH_00341 1.2e-159 EGP Major facilitator Superfamily
CIOKFBHH_00342 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
CIOKFBHH_00343 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CIOKFBHH_00344 8.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CIOKFBHH_00345 3.4e-158 S Alpha/beta hydrolase of unknown function (DUF915)
CIOKFBHH_00346 1.1e-275 pipD E Dipeptidase
CIOKFBHH_00347 0.0 yjbQ P TrkA C-terminal domain protein
CIOKFBHH_00348 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CIOKFBHH_00349 1.1e-283 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CIOKFBHH_00351 0.0 kup P Transport of potassium into the cell
CIOKFBHH_00352 1.9e-56 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIOKFBHH_00353 1.2e-59 M repeat protein
CIOKFBHH_00354 8.1e-09
CIOKFBHH_00355 3.8e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
CIOKFBHH_00356 1.4e-140 yueF S AI-2E family transporter
CIOKFBHH_00357 1.8e-165 ykoT GT2 M Glycosyl transferase family 2
CIOKFBHH_00358 2.2e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CIOKFBHH_00359 1.3e-95 M transferase activity, transferring glycosyl groups
CIOKFBHH_00360 3.1e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
CIOKFBHH_00361 3.6e-148 ykoT GT2 M Glycosyl transferase family 2
CIOKFBHH_00362 5.9e-212 S Psort location CytoplasmicMembrane, score
CIOKFBHH_00363 6.5e-89 S Bacterial membrane protein, YfhO
CIOKFBHH_00364 8.1e-171 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CIOKFBHH_00365 7.8e-64 gntR1 K Transcriptional regulator, GntR family
CIOKFBHH_00366 1.8e-156 V ABC transporter, ATP-binding protein
CIOKFBHH_00367 6.1e-14
CIOKFBHH_00369 1.2e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
CIOKFBHH_00370 6.5e-162 EG EamA-like transporter family
CIOKFBHH_00371 7.1e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CIOKFBHH_00372 1e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
CIOKFBHH_00373 1.7e-97 S Pfam:DUF3816
CIOKFBHH_00374 2e-266 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIOKFBHH_00375 1.4e-109 pncA Q Isochorismatase family
CIOKFBHH_00376 6.4e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
CIOKFBHH_00377 0.0 clpE O Belongs to the ClpA ClpB family
CIOKFBHH_00379 1.4e-38 ptsH G phosphocarrier protein HPR
CIOKFBHH_00380 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIOKFBHH_00381 1.3e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
CIOKFBHH_00382 7.7e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
CIOKFBHH_00383 2.5e-181 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CIOKFBHH_00384 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
CIOKFBHH_00385 1.7e-159 tnp L MULE transposase domain
CIOKFBHH_00386 5.5e-57 ydiI Q Thioesterase superfamily
CIOKFBHH_00387 5.3e-158 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CIOKFBHH_00388 1.3e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CIOKFBHH_00389 1.7e-218 G Transporter, major facilitator family protein
CIOKFBHH_00390 4.7e-207 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
CIOKFBHH_00391 1.5e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CIOKFBHH_00392 1.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CIOKFBHH_00393 2.5e-40 gcvR T Belongs to the UPF0237 family
CIOKFBHH_00394 9.3e-245 XK27_08635 S UPF0210 protein
CIOKFBHH_00395 1.1e-178 yobV1 K WYL domain
CIOKFBHH_00396 4.1e-68 S pyridoxamine 5-phosphate
CIOKFBHH_00397 2.5e-34
CIOKFBHH_00399 3.3e-64
CIOKFBHH_00400 1.3e-112 yicL EG EamA-like transporter family
CIOKFBHH_00401 1.3e-73 S Domain of unknown function (DUF4352)
CIOKFBHH_00402 0.0 1.3.5.4 C FAD binding domain
CIOKFBHH_00403 4.4e-169 K LysR substrate binding domain
CIOKFBHH_00404 4.1e-161 rssA S Phospholipase, patatin family
CIOKFBHH_00405 7.4e-214 phbA 2.3.1.9 I Belongs to the thiolase family
CIOKFBHH_00406 4.7e-178 S AI-2E family transporter
CIOKFBHH_00407 2.9e-123 S membrane transporter protein
CIOKFBHH_00408 1.4e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
CIOKFBHH_00409 3.4e-194 V Beta-lactamase
CIOKFBHH_00410 9.2e-228
CIOKFBHH_00412 6.3e-154 S Alpha/beta hydrolase of unknown function (DUF915)
CIOKFBHH_00413 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIOKFBHH_00414 2.2e-165 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
CIOKFBHH_00415 1.2e-163 endA F DNA RNA non-specific endonuclease
CIOKFBHH_00416 2.7e-268 pipD E Dipeptidase
CIOKFBHH_00418 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CIOKFBHH_00419 7.5e-261 yfnA E Amino Acid
CIOKFBHH_00420 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CIOKFBHH_00421 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CIOKFBHH_00422 5.4e-40 ylqC S Belongs to the UPF0109 family
CIOKFBHH_00423 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CIOKFBHH_00424 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
CIOKFBHH_00425 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CIOKFBHH_00426 5.5e-153 pstA P Phosphate transport system permease protein PstA
CIOKFBHH_00427 5.6e-153 pstC P probably responsible for the translocation of the substrate across the membrane
CIOKFBHH_00428 1.6e-157 pstS P Phosphate
CIOKFBHH_00429 9.8e-129 K Transcriptional regulatory protein, C-terminal domain protein
CIOKFBHH_00430 9.4e-32
CIOKFBHH_00431 4.4e-29
CIOKFBHH_00433 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CIOKFBHH_00434 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CIOKFBHH_00435 1.5e-198 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CIOKFBHH_00436 0.0 smc D Required for chromosome condensation and partitioning
CIOKFBHH_00437 2e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CIOKFBHH_00438 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIOKFBHH_00439 2.8e-164 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CIOKFBHH_00440 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CIOKFBHH_00441 5e-304 yloV S DAK2 domain fusion protein YloV
CIOKFBHH_00442 3.6e-58 asp S Asp23 family, cell envelope-related function
CIOKFBHH_00443 7.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CIOKFBHH_00444 4.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
CIOKFBHH_00445 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CIOKFBHH_00446 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CIOKFBHH_00447 0.0 KLT serine threonine protein kinase
CIOKFBHH_00448 2.2e-131 stp 3.1.3.16 T phosphatase
CIOKFBHH_00449 1e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CIOKFBHH_00450 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CIOKFBHH_00451 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CIOKFBHH_00452 1.8e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CIOKFBHH_00453 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CIOKFBHH_00454 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CIOKFBHH_00455 2.5e-15
CIOKFBHH_00456 7e-306 recN L May be involved in recombinational repair of damaged DNA
CIOKFBHH_00457 6.2e-76 argR K Regulates arginine biosynthesis genes
CIOKFBHH_00458 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CIOKFBHH_00459 9.6e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CIOKFBHH_00460 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIOKFBHH_00461 1.5e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CIOKFBHH_00462 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CIOKFBHH_00463 4e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CIOKFBHH_00464 4.1e-72 yqhY S Asp23 family, cell envelope-related function
CIOKFBHH_00465 8.1e-207 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CIOKFBHH_00466 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CIOKFBHH_00467 9e-53 ysxB J Cysteine protease Prp
CIOKFBHH_00468 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
CIOKFBHH_00469 9.6e-115 K Transcriptional regulator
CIOKFBHH_00471 1.9e-92 dut S Protein conserved in bacteria
CIOKFBHH_00472 5.1e-176
CIOKFBHH_00473 2.4e-148
CIOKFBHH_00474 4.7e-13
CIOKFBHH_00475 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
CIOKFBHH_00476 8.5e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CIOKFBHH_00477 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
CIOKFBHH_00478 1.5e-71 yqhL P Rhodanese-like protein
CIOKFBHH_00479 1.2e-180 glk 2.7.1.2 G Glucokinase
CIOKFBHH_00480 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
CIOKFBHH_00481 1.1e-116 gluP 3.4.21.105 S Peptidase, S54 family
CIOKFBHH_00482 2.4e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CIOKFBHH_00483 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CIOKFBHH_00484 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
CIOKFBHH_00485 0.0 S membrane
CIOKFBHH_00486 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIOKFBHH_00487 3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
CIOKFBHH_00488 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIOKFBHH_00489 5.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CIOKFBHH_00490 7.8e-60 yodB K Transcriptional regulator, HxlR family
CIOKFBHH_00491 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
CIOKFBHH_00492 1.2e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIOKFBHH_00493 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CIOKFBHH_00494 2.9e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIOKFBHH_00495 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CIOKFBHH_00496 1.6e-233 V MatE
CIOKFBHH_00497 9e-281 arlS 2.7.13.3 T Histidine kinase
CIOKFBHH_00498 5.6e-121 K response regulator
CIOKFBHH_00499 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CIOKFBHH_00500 4.6e-97 yceD S Uncharacterized ACR, COG1399
CIOKFBHH_00501 9.3e-214 ylbM S Belongs to the UPF0348 family
CIOKFBHH_00502 8.3e-142 yqeM Q Methyltransferase
CIOKFBHH_00503 6.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CIOKFBHH_00504 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
CIOKFBHH_00505 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CIOKFBHH_00506 2.6e-49 yhbY J RNA-binding protein
CIOKFBHH_00507 2.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
CIOKFBHH_00508 2.2e-96 yqeG S HAD phosphatase, family IIIA
CIOKFBHH_00509 2e-25 yoaK S Protein of unknown function (DUF1275)
CIOKFBHH_00510 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CIOKFBHH_00511 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CIOKFBHH_00512 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CIOKFBHH_00513 2.5e-172 dnaI L Primosomal protein DnaI
CIOKFBHH_00514 3.6e-252 dnaB L replication initiation and membrane attachment
CIOKFBHH_00515 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CIOKFBHH_00516 1e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CIOKFBHH_00517 2.1e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CIOKFBHH_00518 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CIOKFBHH_00519 2.9e-139 aroD S Serine hydrolase (FSH1)
CIOKFBHH_00520 1.8e-114 ybhL S Belongs to the BI1 family
CIOKFBHH_00521 3.6e-249 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CIOKFBHH_00522 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CIOKFBHH_00523 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CIOKFBHH_00524 3.3e-58 ytzB S Small secreted protein
CIOKFBHH_00525 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CIOKFBHH_00526 1.7e-210 ecsB U ABC transporter
CIOKFBHH_00527 2.3e-133 ecsA V ABC transporter, ATP-binding protein
CIOKFBHH_00528 1.4e-77 hit FG histidine triad
CIOKFBHH_00530 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CIOKFBHH_00531 5.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
CIOKFBHH_00532 9.8e-56 yheA S Belongs to the UPF0342 family
CIOKFBHH_00533 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CIOKFBHH_00534 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CIOKFBHH_00536 1.7e-36
CIOKFBHH_00538 2e-200 folP 2.5.1.15 H dihydropteroate synthase
CIOKFBHH_00539 2.2e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
CIOKFBHH_00540 4.9e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CIOKFBHH_00541 1.5e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
CIOKFBHH_00542 8.4e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
CIOKFBHH_00543 2.5e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CIOKFBHH_00544 2.4e-119 S CAAX protease self-immunity
CIOKFBHH_00545 9.9e-183 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
CIOKFBHH_00546 3.6e-111
CIOKFBHH_00547 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
CIOKFBHH_00548 1.8e-164 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIOKFBHH_00549 1.2e-255 S Putative peptidoglycan binding domain
CIOKFBHH_00550 3.3e-86 uspA T Belongs to the universal stress protein A family
CIOKFBHH_00551 8.1e-276 pepV 3.5.1.18 E dipeptidase PepV
CIOKFBHH_00552 2.4e-156 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CIOKFBHH_00553 5e-63 3.2.1.23 S Domain of unknown function DUF302
CIOKFBHH_00554 3.6e-299 ytgP S Polysaccharide biosynthesis protein
CIOKFBHH_00555 2.6e-42
CIOKFBHH_00556 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CIOKFBHH_00557 1.4e-127 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
CIOKFBHH_00558 4.9e-224 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CIOKFBHH_00559 3.7e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CIOKFBHH_00560 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CIOKFBHH_00561 8.5e-51
CIOKFBHH_00562 6.8e-98 tag 3.2.2.20 L glycosylase
CIOKFBHH_00563 5.2e-254 EGP Major facilitator Superfamily
CIOKFBHH_00564 4.8e-84 perR P Belongs to the Fur family
CIOKFBHH_00565 4.5e-247 cycA E Amino acid permease
CIOKFBHH_00566 4e-22
CIOKFBHH_00569 2e-94 K Transcriptional regulator, TetR family
CIOKFBHH_00570 3.7e-78 hsp O Belongs to the small heat shock protein (HSP20) family
CIOKFBHH_00571 1.6e-85 ykhA 3.1.2.20 I Thioesterase superfamily
CIOKFBHH_00572 2e-59 lytE M LysM domain protein
CIOKFBHH_00573 1.7e-201 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
CIOKFBHH_00574 6e-236 F Permease
CIOKFBHH_00575 1.3e-162 sufD O Uncharacterized protein family (UPF0051)
CIOKFBHH_00576 1.1e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CIOKFBHH_00577 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CIOKFBHH_00578 4.5e-110 XK27_05795 P ABC transporter permease
CIOKFBHH_00579 2.4e-142 ET Bacterial periplasmic substrate-binding proteins
CIOKFBHH_00580 1.1e-10 qacC P COG2076 Membrane transporters of cations and cationic drugs
CIOKFBHH_00583 4.2e-123 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CIOKFBHH_00584 1.7e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CIOKFBHH_00585 6.7e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
CIOKFBHH_00586 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CIOKFBHH_00587 1.6e-244 glpT G Major Facilitator Superfamily
CIOKFBHH_00588 1.3e-129 qmcA O prohibitin homologues
CIOKFBHH_00590 3.1e-75 uspA T universal stress protein
CIOKFBHH_00591 2.1e-59
CIOKFBHH_00592 6.6e-20
CIOKFBHH_00593 4.5e-160
CIOKFBHH_00594 8.4e-75 K Transcriptional regulator
CIOKFBHH_00595 2.8e-187 D Alpha beta
CIOKFBHH_00596 1.6e-73 O OsmC-like protein
CIOKFBHH_00597 4e-192 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
CIOKFBHH_00598 0.0 yjcE P Sodium proton antiporter
CIOKFBHH_00599 1.2e-16 yvlA
CIOKFBHH_00600 7.5e-115 P Cobalt transport protein
CIOKFBHH_00601 1.6e-255 cbiO1 S ABC transporter, ATP-binding protein
CIOKFBHH_00602 1.6e-100 S ABC-type cobalt transport system, permease component
CIOKFBHH_00603 3.1e-178 iunH2 3.2.2.1 F nucleoside hydrolase
CIOKFBHH_00604 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
CIOKFBHH_00605 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
CIOKFBHH_00606 2.8e-32 copZ P Heavy-metal-associated domain
CIOKFBHH_00607 2.6e-100 dps P Belongs to the Dps family
CIOKFBHH_00608 4.4e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
CIOKFBHH_00609 2e-85
CIOKFBHH_00610 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CIOKFBHH_00611 2.5e-126 pgm3 G phosphoglycerate mutase family
CIOKFBHH_00612 1.9e-150 qorB 1.6.5.2 GM NmrA-like family
CIOKFBHH_00613 4.1e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CIOKFBHH_00614 0.0 sbcC L Putative exonuclease SbcCD, C subunit
CIOKFBHH_00615 8.7e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CIOKFBHH_00617 8.3e-298 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIOKFBHH_00618 7e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
CIOKFBHH_00619 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CIOKFBHH_00620 1.9e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CIOKFBHH_00621 1.2e-121 iolS C Aldo keto reductase
CIOKFBHH_00622 5.7e-197 brnQ U Component of the transport system for branched-chain amino acids
CIOKFBHH_00623 1.3e-244 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CIOKFBHH_00624 4.9e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
CIOKFBHH_00625 5.8e-97 metI P ABC transporter permease
CIOKFBHH_00626 6.1e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CIOKFBHH_00627 2.7e-149 metQ1 P Belongs to the nlpA lipoprotein family
CIOKFBHH_00628 3.3e-259 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
CIOKFBHH_00629 3.2e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
CIOKFBHH_00630 6.9e-47
CIOKFBHH_00631 4e-17 gntT EG gluconate transmembrane transporter activity
CIOKFBHH_00632 1.1e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CIOKFBHH_00633 2.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CIOKFBHH_00634 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CIOKFBHH_00635 1.3e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
CIOKFBHH_00636 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CIOKFBHH_00637 7.4e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIOKFBHH_00638 2.5e-37 K transcriptional regulator
CIOKFBHH_00639 4.1e-21 L Transposase
CIOKFBHH_00640 9.1e-36 T Belongs to the universal stress protein A family
CIOKFBHH_00641 6e-251 mntH P H( )-stimulated, divalent metal cation uptake system
CIOKFBHH_00642 1.5e-21
CIOKFBHH_00643 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CIOKFBHH_00644 7.5e-69 L nuclease
CIOKFBHH_00645 4.9e-162 F DNA/RNA non-specific endonuclease
CIOKFBHH_00646 1.9e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CIOKFBHH_00647 6.4e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIOKFBHH_00648 3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CIOKFBHH_00649 0.0 asnB 6.3.5.4 E Asparagine synthase
CIOKFBHH_00650 6.6e-220 lysP E amino acid
CIOKFBHH_00651 7e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CIOKFBHH_00652 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CIOKFBHH_00653 1.1e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CIOKFBHH_00654 4.8e-154 jag S R3H domain protein
CIOKFBHH_00655 3.4e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CIOKFBHH_00656 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CIOKFBHH_00657 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
CIOKFBHH_00659 5.2e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CIOKFBHH_00660 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CIOKFBHH_00661 2.2e-34 yaaA S S4 domain protein YaaA
CIOKFBHH_00662 5.6e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CIOKFBHH_00663 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIOKFBHH_00664 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CIOKFBHH_00665 6.1e-183 fecB P Periplasmic binding protein
CIOKFBHH_00666 4.2e-272 sufB O assembly protein SufB
CIOKFBHH_00667 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
CIOKFBHH_00668 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CIOKFBHH_00669 1.7e-243 sufD O FeS assembly protein SufD
CIOKFBHH_00670 8.5e-145 sufC O FeS assembly ATPase SufC
CIOKFBHH_00671 1.4e-33 feoA P FeoA domain
CIOKFBHH_00672 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
CIOKFBHH_00673 6.7e-23 S Virus attachment protein p12 family
CIOKFBHH_00674 2.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
CIOKFBHH_00675 2.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CIOKFBHH_00676 2.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIOKFBHH_00677 7.1e-217 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
CIOKFBHH_00678 8.7e-90 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CIOKFBHH_00679 6.9e-198 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CIOKFBHH_00680 1e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CIOKFBHH_00681 1.2e-102
CIOKFBHH_00682 6.7e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CIOKFBHH_00683 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
CIOKFBHH_00684 6.4e-213 ydiN G Major Facilitator Superfamily
CIOKFBHH_00686 5.1e-244 dtpT U amino acid peptide transporter
CIOKFBHH_00689 2.5e-152 S Sucrose-6F-phosphate phosphohydrolase
CIOKFBHH_00690 6.3e-45 1.6.5.2 GM NAD(P)H-binding
CIOKFBHH_00691 3.5e-91 1.6.5.2 GM NAD(P)H-binding
CIOKFBHH_00692 5.5e-158 S Alpha beta hydrolase
CIOKFBHH_00693 2.7e-237 lmrB EGP Major facilitator Superfamily
CIOKFBHH_00695 0.0 S Bacterial membrane protein YfhO
CIOKFBHH_00696 3.2e-42
CIOKFBHH_00697 1.9e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CIOKFBHH_00698 3.1e-10 K transcriptional regulator
CIOKFBHH_00699 3.7e-164 K AI-2E family transporter
CIOKFBHH_00700 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CIOKFBHH_00701 1.8e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CIOKFBHH_00702 1.5e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CIOKFBHH_00703 3.3e-255 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CIOKFBHH_00704 2.1e-172 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
CIOKFBHH_00705 9.1e-236 S response to antibiotic
CIOKFBHH_00706 2.5e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CIOKFBHH_00707 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIOKFBHH_00708 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIOKFBHH_00709 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CIOKFBHH_00710 5.7e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CIOKFBHH_00711 1.1e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CIOKFBHH_00712 6e-108 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CIOKFBHH_00713 2.9e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CIOKFBHH_00714 4.5e-241 purD 6.3.4.13 F Belongs to the GARS family
CIOKFBHH_00715 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIOKFBHH_00716 5.1e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
CIOKFBHH_00717 1.9e-178
CIOKFBHH_00718 8.5e-47 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CIOKFBHH_00719 5e-53 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
CIOKFBHH_00720 0.0 copA 3.6.3.54 P P-type ATPase
CIOKFBHH_00721 3.8e-30 EGP Major facilitator Superfamily
CIOKFBHH_00722 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
CIOKFBHH_00723 2.9e-94 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIOKFBHH_00724 4.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CIOKFBHH_00725 1.5e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
CIOKFBHH_00726 8.2e-182 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CIOKFBHH_00727 2.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
CIOKFBHH_00728 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CIOKFBHH_00729 1.6e-88 ypmB S Protein conserved in bacteria
CIOKFBHH_00730 2.1e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
CIOKFBHH_00731 4.7e-134 dnaD L DnaD domain protein
CIOKFBHH_00732 1.3e-121 ypuA S Protein of unknown function (DUF1002)
CIOKFBHH_00733 5.3e-192 C Aldo keto reductase family protein
CIOKFBHH_00734 3.7e-160 EG EamA-like transporter family
CIOKFBHH_00735 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
CIOKFBHH_00736 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CIOKFBHH_00737 3.9e-110 ypsA S Belongs to the UPF0398 family
CIOKFBHH_00738 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CIOKFBHH_00739 0.0 tetP J elongation factor G
CIOKFBHH_00740 1.4e-212 S Type IV secretion-system coupling protein DNA-binding domain
CIOKFBHH_00741 8.9e-83 F Hydrolase, NUDIX family
CIOKFBHH_00742 1.9e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CIOKFBHH_00743 5.6e-128 arcD S C4-dicarboxylate anaerobic carrier
CIOKFBHH_00744 1.2e-272 nylA 3.5.1.4 J Belongs to the amidase family
CIOKFBHH_00746 2.3e-87 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
CIOKFBHH_00747 1.1e-107 ygfC K Bacterial regulatory proteins, tetR family
CIOKFBHH_00748 7.3e-157 hrtB V ABC transporter permease
CIOKFBHH_00749 6.7e-122 devA 3.6.3.25 V ABC transporter, ATP-binding protein
CIOKFBHH_00750 1.8e-75 argR K Regulates arginine biosynthesis genes
CIOKFBHH_00751 7.6e-46 czrA K Transcriptional regulator, ArsR family
CIOKFBHH_00752 1.7e-173 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CIOKFBHH_00753 6.3e-171 scrR K Transcriptional regulator, LacI family
CIOKFBHH_00754 9.5e-26
CIOKFBHH_00755 3.2e-102
CIOKFBHH_00756 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CIOKFBHH_00757 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
CIOKFBHH_00758 3.3e-55
CIOKFBHH_00759 4.8e-125 yrkL S Flavodoxin-like fold
CIOKFBHH_00761 6.8e-65 yeaO S Protein of unknown function, DUF488
CIOKFBHH_00762 1.3e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
CIOKFBHH_00763 1.4e-204 3.1.3.1 S associated with various cellular activities
CIOKFBHH_00764 1.9e-212 S Putative metallopeptidase domain
CIOKFBHH_00765 2.1e-45
CIOKFBHH_00766 1.8e-229 pbuG S permease
CIOKFBHH_00767 0.0 pepO 3.4.24.71 O Peptidase family M13
CIOKFBHH_00768 1.1e-92 ymdB S Macro domain protein
CIOKFBHH_00769 6.9e-147 pnuC H nicotinamide mononucleotide transporter
CIOKFBHH_00770 1.7e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CIOKFBHH_00771 9e-170 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIOKFBHH_00772 2e-52
CIOKFBHH_00773 5.7e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
CIOKFBHH_00774 5.3e-119 tcyB U Binding-protein-dependent transport system inner membrane component
CIOKFBHH_00775 2.5e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIOKFBHH_00776 6.9e-36
CIOKFBHH_00777 1e-95 yxkA S Phosphatidylethanolamine-binding protein
CIOKFBHH_00778 1.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
CIOKFBHH_00779 7.7e-185 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
CIOKFBHH_00781 6.3e-16 2.1.1.303 K DNA-binding transcription factor activity
CIOKFBHH_00782 1.7e-285 L Recombinase
CIOKFBHH_00783 1.1e-274 L Recombinase zinc beta ribbon domain
CIOKFBHH_00784 4.8e-32
CIOKFBHH_00785 4.3e-68 S Bacteriophage holin family
CIOKFBHH_00786 8.4e-66 S Phage head-tail joining protein
CIOKFBHH_00787 4.3e-43 S Phage gp6-like head-tail connector protein
CIOKFBHH_00788 2.2e-218 S Phage capsid family
CIOKFBHH_00789 1.4e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
CIOKFBHH_00790 5.3e-242 S Phage portal protein
CIOKFBHH_00791 1.1e-305 S overlaps another CDS with the same product name
CIOKFBHH_00792 1.8e-30 S Domain of unknown function (DUF5049)
CIOKFBHH_00793 2.4e-110 S Psort location Cytoplasmic, score
CIOKFBHH_00794 2.7e-230 2.1.1.72 KL DNA methylase
CIOKFBHH_00795 1.4e-98
CIOKFBHH_00796 8.9e-86
CIOKFBHH_00797 3.8e-246 L SNF2 family N-terminal domain
CIOKFBHH_00798 1.5e-43 S VRR_NUC
CIOKFBHH_00799 0.0 S Phage plasmid primase, P4
CIOKFBHH_00800 2.8e-69 S Psort location Cytoplasmic, score
CIOKFBHH_00801 0.0 polA_2 2.7.7.7 L DNA polymerase
CIOKFBHH_00802 4.4e-92 S Protein of unknown function (DUF2815)
CIOKFBHH_00803 4.5e-68 L Protein of unknown function (DUF2800)
CIOKFBHH_00804 2.4e-125 L Protein of unknown function (DUF2800)
CIOKFBHH_00805 8e-28
CIOKFBHH_00806 5.5e-24
CIOKFBHH_00807 1.9e-56 K DNA-templated transcription, initiation
CIOKFBHH_00808 4.6e-90
CIOKFBHH_00809 1.3e-28 K Cro/C1-type HTH DNA-binding domain
CIOKFBHH_00810 2.1e-285 2.1.1.72 V type I restriction-modification system
CIOKFBHH_00811 4.3e-29 3.1.21.3 V Type I restriction modification DNA specificity domain
CIOKFBHH_00812 1.6e-261 arcD E Amino acid permease
CIOKFBHH_00813 4.2e-117 5.1.1.13 M racemase activity, acting on amino acids and derivatives
CIOKFBHH_00814 1e-157 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
CIOKFBHH_00815 5.5e-11 clcA P chloride
CIOKFBHH_00816 1.4e-51 clcA P chloride
CIOKFBHH_00817 6.5e-18 lmrB EGP Major facilitator Superfamily
CIOKFBHH_00819 9.3e-245 yhjX P Major Facilitator Superfamily
CIOKFBHH_00820 4.4e-118 S Protein of unknown function (DUF554)
CIOKFBHH_00821 2.6e-255 rarA L recombination factor protein RarA
CIOKFBHH_00823 0.0 oppD EP Psort location Cytoplasmic, score
CIOKFBHH_00824 4e-242 codA 3.5.4.1 F cytosine deaminase
CIOKFBHH_00825 4.7e-244 U Belongs to the purine-cytosine permease (2.A.39) family
CIOKFBHH_00826 2.2e-81 yebR 1.8.4.14 T GAF domain-containing protein
CIOKFBHH_00827 5.7e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
CIOKFBHH_00828 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CIOKFBHH_00829 2.3e-71 yqkB S Belongs to the HesB IscA family
CIOKFBHH_00830 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
CIOKFBHH_00831 5.2e-95 S Protein of unknown function (DUF1440)
CIOKFBHH_00832 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIOKFBHH_00833 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CIOKFBHH_00834 2.8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CIOKFBHH_00835 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
CIOKFBHH_00836 1.2e-154 D DNA integration
CIOKFBHH_00837 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
CIOKFBHH_00838 5e-37 S Cytochrome B5
CIOKFBHH_00841 9.2e-16 S Domain of unknown function (DUF4811)
CIOKFBHH_00842 8.4e-58 lmrB EGP Major facilitator Superfamily
CIOKFBHH_00843 4.9e-174 lmrB EGP Major facilitator Superfamily
CIOKFBHH_00844 8.5e-96 K transcriptional regulator
CIOKFBHH_00845 2.2e-72 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
CIOKFBHH_00846 0.0 L Helicase C-terminal domain protein
CIOKFBHH_00847 7.8e-54 S MazG-like family
CIOKFBHH_00848 1.4e-107 lssY 3.6.1.27 I Acid phosphatase homologues
CIOKFBHH_00849 5.8e-146 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
CIOKFBHH_00850 3.4e-43 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
CIOKFBHH_00851 1.3e-96
CIOKFBHH_00852 1.1e-223 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CIOKFBHH_00853 2e-169 ponA V Beta-lactamase enzyme family
CIOKFBHH_00854 9e-265 yjeM E Amino Acid
CIOKFBHH_00856 5.5e-112
CIOKFBHH_00857 2.6e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
CIOKFBHH_00858 3.2e-164 K LysR substrate binding domain
CIOKFBHH_00859 1.9e-261 S Uncharacterized protein conserved in bacteria (DUF2252)
CIOKFBHH_00860 4.5e-301 scrB 3.2.1.26 GH32 G invertase
CIOKFBHH_00861 1.8e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
CIOKFBHH_00862 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
CIOKFBHH_00863 3.6e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CIOKFBHH_00864 1.7e-243 steT E amino acid
CIOKFBHH_00865 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CIOKFBHH_00866 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CIOKFBHH_00867 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
CIOKFBHH_00868 4.1e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
CIOKFBHH_00869 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CIOKFBHH_00870 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CIOKFBHH_00871 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CIOKFBHH_00872 7.8e-247 brnQ U Component of the transport system for branched-chain amino acids
CIOKFBHH_00873 7.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIOKFBHH_00874 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIOKFBHH_00875 2e-35 nrdH O Glutaredoxin
CIOKFBHH_00876 1.5e-78 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CIOKFBHH_00878 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CIOKFBHH_00879 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CIOKFBHH_00880 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CIOKFBHH_00881 2.4e-21 S Protein of unknown function (DUF2508)
CIOKFBHH_00882 6e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CIOKFBHH_00883 1.2e-52 yaaQ S Cyclic-di-AMP receptor
CIOKFBHH_00884 4.9e-193 holB 2.7.7.7 L DNA polymerase III
CIOKFBHH_00885 1.5e-55 yabA L Involved in initiation control of chromosome replication
CIOKFBHH_00886 1.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CIOKFBHH_00887 2.8e-145 fat 3.1.2.21 I Acyl-ACP thioesterase
CIOKFBHH_00888 1.1e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CIOKFBHH_00889 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CIOKFBHH_00890 2.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CIOKFBHH_00891 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CIOKFBHH_00892 1.8e-148 KT YcbB domain
CIOKFBHH_00893 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CIOKFBHH_00894 1.4e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
CIOKFBHH_00895 8.2e-240 arcA 3.5.3.6 E Arginine
CIOKFBHH_00896 1.1e-259 E Arginine ornithine antiporter
CIOKFBHH_00897 3.6e-218 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
CIOKFBHH_00898 7.6e-216 arcT 2.6.1.1 E Aminotransferase
CIOKFBHH_00899 5.8e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
CIOKFBHH_00900 3.9e-110 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
CIOKFBHH_00901 1.2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CIOKFBHH_00903 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CIOKFBHH_00904 8.7e-75 marR K Transcriptional regulator, MarR family
CIOKFBHH_00905 2.2e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CIOKFBHH_00906 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CIOKFBHH_00907 4.1e-170 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CIOKFBHH_00908 2.7e-129 IQ reductase
CIOKFBHH_00909 6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CIOKFBHH_00910 1.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CIOKFBHH_00911 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CIOKFBHH_00912 1.6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
CIOKFBHH_00913 6.4e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CIOKFBHH_00914 5.2e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
CIOKFBHH_00915 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
CIOKFBHH_00916 9.7e-92 bioY S BioY family
CIOKFBHH_00917 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CIOKFBHH_00918 0.0 uup S ABC transporter, ATP-binding protein
CIOKFBHH_00919 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CIOKFBHH_00920 7.4e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CIOKFBHH_00921 4.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CIOKFBHH_00922 0.0 ydaO E amino acid
CIOKFBHH_00923 6.4e-38
CIOKFBHH_00924 1.2e-112 yvyE 3.4.13.9 S YigZ family
CIOKFBHH_00925 4.2e-250 comFA L Helicase C-terminal domain protein
CIOKFBHH_00926 3e-127 comFC S Competence protein
CIOKFBHH_00927 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CIOKFBHH_00928 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CIOKFBHH_00929 4.5e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CIOKFBHH_00930 4.1e-53 KT PspC domain protein
CIOKFBHH_00931 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
CIOKFBHH_00932 1e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CIOKFBHH_00933 4e-161 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CIOKFBHH_00934 5.3e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CIOKFBHH_00935 6e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CIOKFBHH_00936 2.3e-147 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
CIOKFBHH_00937 5.9e-227 mtnE 2.6.1.83 E Aminotransferase
CIOKFBHH_00938 7.6e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CIOKFBHH_00939 3.2e-125 thrE S Putative threonine/serine exporter
CIOKFBHH_00940 2.8e-82 S Threonine/Serine exporter, ThrE
CIOKFBHH_00941 9.1e-116 lssY 3.6.1.27 I phosphatase
CIOKFBHH_00942 1.8e-155 I alpha/beta hydrolase fold
CIOKFBHH_00944 3.9e-268 lysP E amino acid
CIOKFBHH_00945 1e-116 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
CIOKFBHH_00951 1.2e-90 IQ reductase
CIOKFBHH_00952 5.5e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CIOKFBHH_00953 1.2e-16 S ABC-type cobalt transport system, permease component
CIOKFBHH_00954 9.1e-40 S ABC-type cobalt transport system, permease component
CIOKFBHH_00955 7.9e-72 thiW S Thiamine-precursor transporter protein (ThiW)
CIOKFBHH_00956 9.7e-40 rmeB K transcriptional regulator, MerR family
CIOKFBHH_00957 2.8e-38 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
CIOKFBHH_00958 2.7e-120 J 2'-5' RNA ligase superfamily
CIOKFBHH_00959 1.9e-132 XK27_07210 6.1.1.6 S B3 4 domain
CIOKFBHH_00960 9.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
CIOKFBHH_00961 4.8e-79 ctsR K Belongs to the CtsR family
CIOKFBHH_00962 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CIOKFBHH_00963 5.8e-106 K Bacterial regulatory proteins, tetR family
CIOKFBHH_00964 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIOKFBHH_00965 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CIOKFBHH_00967 0.0 asnB 6.3.5.4 E Aluminium induced protein
CIOKFBHH_00969 1.4e-12 S CHY zinc finger
CIOKFBHH_00971 1.1e-06 M domain protein
CIOKFBHH_00972 2.4e-16 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
CIOKFBHH_00973 2.8e-12
CIOKFBHH_00974 1.3e-182 scrR3 K Transcriptional regulator, LacI family
CIOKFBHH_00975 6.5e-78 F Nucleoside 2-deoxyribosyltransferase
CIOKFBHH_00976 2.1e-90
CIOKFBHH_00978 3.3e-200 L Belongs to the 'phage' integrase family
CIOKFBHH_00979 8.9e-58
CIOKFBHH_00981 3.7e-129 S Domain of unknown function (DUF4393)
CIOKFBHH_00982 2e-23
CIOKFBHH_00983 1.1e-21 E Zn peptidase
CIOKFBHH_00984 2.9e-147 S Protein of unknown function (DUF3644)
CIOKFBHH_00985 5.8e-44 3.4.21.88 K Helix-turn-helix domain
CIOKFBHH_00986 8.9e-147 K Phage regulatory protein
CIOKFBHH_00990 7.2e-10 S Domain of unknown function (DUF771)
CIOKFBHH_00996 3.8e-93 recT L RecT family
CIOKFBHH_00997 2.6e-33 recT L RecT family
CIOKFBHH_00998 4.5e-152 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
CIOKFBHH_00999 2e-94 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CIOKFBHH_01000 1.4e-26 L Psort location Cytoplasmic, score
CIOKFBHH_01003 4.2e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIOKFBHH_01005 1.1e-41 K Helix-turn-helix domain
CIOKFBHH_01006 2e-37 XK26_04895
CIOKFBHH_01007 1.2e-167 D nuclear chromosome segregation
CIOKFBHH_01008 3.7e-258 dtpT U amino acid peptide transporter
CIOKFBHH_01009 2.1e-165 yjjH S Calcineurin-like phosphoesterase
CIOKFBHH_01012 3.3e-115
CIOKFBHH_01013 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CIOKFBHH_01014 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
CIOKFBHH_01015 1.1e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CIOKFBHH_01016 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CIOKFBHH_01017 0.0 yhgF K Tex-like protein N-terminal domain protein
CIOKFBHH_01018 2.4e-83 ydcK S Belongs to the SprT family
CIOKFBHH_01020 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
CIOKFBHH_01021 1.8e-189 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
CIOKFBHH_01022 2.3e-168 mleP2 S Sodium Bile acid symporter family
CIOKFBHH_01023 5.2e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CIOKFBHH_01024 1.3e-167 I alpha/beta hydrolase fold
CIOKFBHH_01025 1.2e-263 pepC 3.4.22.40 E Peptidase C1-like family
CIOKFBHH_01026 5.3e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
CIOKFBHH_01027 1.1e-116 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CIOKFBHH_01028 8.8e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
CIOKFBHH_01029 5.1e-251 yjjP S Putative threonine/serine exporter
CIOKFBHH_01030 6.6e-162 mleR K LysR family transcriptional regulator
CIOKFBHH_01031 3.1e-147 ydjP I Alpha/beta hydrolase family
CIOKFBHH_01032 2.3e-257 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CIOKFBHH_01033 8.6e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
CIOKFBHH_01034 4.2e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
CIOKFBHH_01035 5.7e-46 citD C Covalent carrier of the coenzyme of citrate lyase
CIOKFBHH_01036 6.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CIOKFBHH_01037 2.9e-210 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
CIOKFBHH_01038 1e-173 citR K sugar-binding domain protein
CIOKFBHH_01039 1.6e-231 P Sodium:sulfate symporter transmembrane region
CIOKFBHH_01040 1e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CIOKFBHH_01041 2.4e-219 frdC 1.3.5.4 C FAD binding domain
CIOKFBHH_01042 6.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CIOKFBHH_01043 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
CIOKFBHH_01044 4.6e-183 XK27_09615 S reductase
CIOKFBHH_01045 1.4e-229 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
CIOKFBHH_01046 5.3e-79 mleR K LysR family
CIOKFBHH_01047 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CIOKFBHH_01048 3.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CIOKFBHH_01049 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CIOKFBHH_01050 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CIOKFBHH_01051 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CIOKFBHH_01052 1.4e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CIOKFBHH_01053 3e-87 yabR J RNA binding
CIOKFBHH_01054 1.5e-56 divIC D Septum formation initiator
CIOKFBHH_01055 1.6e-39 yabO J S4 domain protein
CIOKFBHH_01056 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CIOKFBHH_01057 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CIOKFBHH_01058 8.1e-114 S (CBS) domain
CIOKFBHH_01059 5e-57 L Toxic component of a toxin-antitoxin (TA) module
CIOKFBHH_01060 2.8e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CIOKFBHH_01061 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CIOKFBHH_01062 1.9e-254 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CIOKFBHH_01063 6.2e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CIOKFBHH_01064 4.9e-157 htpX O Belongs to the peptidase M48B family
CIOKFBHH_01065 8.7e-88 lemA S LemA family
CIOKFBHH_01066 9e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CIOKFBHH_01067 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIOKFBHH_01068 1.2e-163 S Tetratricopeptide repeat
CIOKFBHH_01069 3.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CIOKFBHH_01070 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CIOKFBHH_01071 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CIOKFBHH_01072 2.8e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
CIOKFBHH_01073 1.9e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
CIOKFBHH_01075 3.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIOKFBHH_01076 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CIOKFBHH_01077 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CIOKFBHH_01078 8.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CIOKFBHH_01079 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CIOKFBHH_01080 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CIOKFBHH_01081 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CIOKFBHH_01082 5.6e-62 S Domain of unknown function (DUF4440)
CIOKFBHH_01083 8.6e-187 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIOKFBHH_01084 3.3e-152 tesE Q hydratase
CIOKFBHH_01085 1.6e-07 tlpA2 L Transposase IS200 like
CIOKFBHH_01086 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CIOKFBHH_01087 5.6e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CIOKFBHH_01088 9.9e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
CIOKFBHH_01089 5.5e-55 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CIOKFBHH_01090 1.7e-94 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CIOKFBHH_01091 7.8e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CIOKFBHH_01092 2.4e-50 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CIOKFBHH_01093 1.1e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CIOKFBHH_01094 0.0 dnaK O Heat shock 70 kDa protein
CIOKFBHH_01095 2.2e-57 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CIOKFBHH_01096 1.3e-190 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CIOKFBHH_01097 2e-61
CIOKFBHH_01098 2.5e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIOKFBHH_01099 1.3e-60 uvrA2 L ABC transporter
CIOKFBHH_01100 7.3e-253 uvrA2 L ABC transporter
CIOKFBHH_01101 6.8e-127 tnp L DDE domain
CIOKFBHH_01102 5.3e-63
CIOKFBHH_01103 1.5e-186 L PFAM Integrase, catalytic core
CIOKFBHH_01104 3.9e-152 S CD20-like family
CIOKFBHH_01105 6.8e-127 tnp L DDE domain
CIOKFBHH_01106 6.6e-237 G Major Facilitator
CIOKFBHH_01107 1.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
CIOKFBHH_01108 1.6e-233 mepA V MATE efflux family protein
CIOKFBHH_01109 9.7e-225 amtB P ammonium transporter
CIOKFBHH_01111 1.4e-133 XK27_08845 S ABC transporter, ATP-binding protein
CIOKFBHH_01112 6.6e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
CIOKFBHH_01113 7e-181 ABC-SBP S ABC transporter
CIOKFBHH_01114 2.2e-290 S ABC transporter, ATP-binding protein
CIOKFBHH_01115 8.9e-206 nrnB S DHHA1 domain
CIOKFBHH_01117 5.1e-110 M ErfK YbiS YcfS YnhG
CIOKFBHH_01118 1.4e-83 nrdI F NrdI Flavodoxin like
CIOKFBHH_01119 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CIOKFBHH_01120 9.7e-169 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
CIOKFBHH_01121 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
CIOKFBHH_01122 5e-275 S Uncharacterized protein conserved in bacteria (DUF2325)
CIOKFBHH_01123 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
CIOKFBHH_01124 3.1e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
CIOKFBHH_01125 7.9e-224 4.4.1.8 E Aminotransferase, class I
CIOKFBHH_01126 3.2e-180 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CIOKFBHH_01127 9.2e-203 xerS L Belongs to the 'phage' integrase family
CIOKFBHH_01128 3.1e-62 ywkB S Membrane transport protein
CIOKFBHH_01129 9.6e-236 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
CIOKFBHH_01130 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
CIOKFBHH_01131 1.3e-79 hmpT S ECF-type riboflavin transporter, S component
CIOKFBHH_01132 5.1e-167 1.1.1.346 C Aldo keto reductase
CIOKFBHH_01133 1.7e-160 S DUF218 domain
CIOKFBHH_01136 1.4e-95 K Acetyltransferase (GNAT) domain
CIOKFBHH_01137 1.1e-163 I alpha/beta hydrolase fold
CIOKFBHH_01138 4.9e-125 S Phage minor capsid protein 2
CIOKFBHH_01141 3.4e-216 2.6.1.1 E Aminotransferase
CIOKFBHH_01142 1.5e-184 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
CIOKFBHH_01143 1.6e-219 EGP Sugar (and other) transporter
CIOKFBHH_01144 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
CIOKFBHH_01146 2.4e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CIOKFBHH_01147 2.2e-22 L hmm pf00665
CIOKFBHH_01148 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
CIOKFBHH_01149 1.3e-28 L Transposase
CIOKFBHH_01150 7e-124 S Membrane
CIOKFBHH_01151 5.4e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CIOKFBHH_01152 0.0 pepF E oligoendopeptidase F
CIOKFBHH_01153 1.7e-179 K helix_turn _helix lactose operon repressor
CIOKFBHH_01154 6.7e-139 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CIOKFBHH_01155 1.9e-77 K AsnC family
CIOKFBHH_01156 1.4e-81 uspA T universal stress protein
CIOKFBHH_01157 9.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CIOKFBHH_01158 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CIOKFBHH_01159 3.2e-206 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CIOKFBHH_01160 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CIOKFBHH_01161 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CIOKFBHH_01162 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CIOKFBHH_01163 3.8e-156 recO L Involved in DNA repair and RecF pathway recombination
CIOKFBHH_01164 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CIOKFBHH_01165 1e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CIOKFBHH_01166 1.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CIOKFBHH_01167 2.5e-178 phoH T phosphate starvation-inducible protein PhoH
CIOKFBHH_01168 4.6e-71 yqeY S YqeY-like protein
CIOKFBHH_01169 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CIOKFBHH_01170 5.1e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
CIOKFBHH_01171 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CIOKFBHH_01172 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
CIOKFBHH_01173 6.1e-196 6.3.1.20 H Lipoate-protein ligase
CIOKFBHH_01174 3.7e-174 lytH 3.5.1.28 M Ami_3
CIOKFBHH_01175 3.4e-168 yniA G Phosphotransferase enzyme family
CIOKFBHH_01176 1.5e-172 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
CIOKFBHH_01177 2e-245 mmuP E amino acid
CIOKFBHH_01178 2.9e-156 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
CIOKFBHH_01179 3.5e-45 hom1 1.1.1.3 E Homoserine dehydrogenase
CIOKFBHH_01180 1.4e-139 hom1 1.1.1.3 E Homoserine dehydrogenase
CIOKFBHH_01182 3.9e-136 IQ KR domain
CIOKFBHH_01183 6.9e-153 cjaA ET ABC transporter substrate-binding protein
CIOKFBHH_01184 1.1e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIOKFBHH_01185 2e-115 P ABC transporter permease
CIOKFBHH_01186 4.2e-113 papP P ABC transporter, permease protein
CIOKFBHH_01188 2.6e-90 yxeQ S MmgE/PrpD family
CIOKFBHH_01189 1.1e-171 pcaB 4.3.2.2 F Adenylosuccinate lyase C-terminus
CIOKFBHH_01190 1.7e-146 3.5.1.47 E Peptidase dimerisation domain
CIOKFBHH_01191 3.4e-78 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
CIOKFBHH_01192 2.2e-70 yxeN U ABC transporter, permease protein
CIOKFBHH_01193 4.1e-47 yxeL K acetyltransferase
CIOKFBHH_01194 3.1e-67 yxeM ET Bacterial periplasmic substrate-binding proteins
CIOKFBHH_01196 3.3e-211 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
CIOKFBHH_01197 9.2e-220 metC1 2.5.1.48, 4.4.1.8 E cystathionine
CIOKFBHH_01198 3.5e-85 slyA K Transcriptional regulator
CIOKFBHH_01199 2.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CIOKFBHH_01200 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CIOKFBHH_01201 5.2e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CIOKFBHH_01202 2e-177 prmA J Ribosomal protein L11 methyltransferase
CIOKFBHH_01203 1.2e-54
CIOKFBHH_01205 5.2e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CIOKFBHH_01206 1.6e-219 L Probable transposase
CIOKFBHH_01207 1.7e-98 S integral membrane protein
CIOKFBHH_01209 1.8e-34 aes I Carboxylesterase family
CIOKFBHH_01210 9.6e-34 aes I Hydrolase, alpha beta domain protein
CIOKFBHH_01212 5.5e-36 S CRISPR-associated protein (Cas_Csn2)
CIOKFBHH_01213 8.4e-35 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CIOKFBHH_01214 7.7e-94 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CIOKFBHH_01215 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CIOKFBHH_01216 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CIOKFBHH_01217 1.9e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CIOKFBHH_01218 2.7e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CIOKFBHH_01219 4.5e-112 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CIOKFBHH_01220 7.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CIOKFBHH_01221 8.6e-67 psiE S Phosphate-starvation-inducible E
CIOKFBHH_01222 1.2e-36 V CAAX protease self-immunity
CIOKFBHH_01223 3.9e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIOKFBHH_01224 1.1e-158 P Belongs to the nlpA lipoprotein family
CIOKFBHH_01225 1.2e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CIOKFBHH_01226 3.2e-116 S Protein of unknown function (DUF554)
CIOKFBHH_01227 5.7e-101 P Cadmium resistance transporter
CIOKFBHH_01228 2.1e-311 mco Q Multicopper oxidase
CIOKFBHH_01229 6.8e-24
CIOKFBHH_01230 2.9e-125 tnp L DDE domain
CIOKFBHH_01231 4.9e-103
CIOKFBHH_01233 8.8e-30 S Protein of unknown function (DUF3021)
CIOKFBHH_01234 3.1e-27 K LytTr DNA-binding domain
CIOKFBHH_01235 6.6e-32 K Transcriptional regulator, ArsR family
CIOKFBHH_01236 6.2e-57 P Cadmium resistance transporter
CIOKFBHH_01237 8e-42 S RelB antitoxin
CIOKFBHH_01238 5.4e-14
CIOKFBHH_01239 6.7e-156 repA S Replication initiator protein A
CIOKFBHH_01241 1.1e-141 D CobQ CobB MinD ParA nucleotide binding domain protein
CIOKFBHH_01242 1.4e-93 L Resolvase, N terminal domain
CIOKFBHH_01243 8.1e-236 EGP Major Facilitator Superfamily
CIOKFBHH_01245 1.9e-112 3.1.3.73 G phosphoglycerate mutase
CIOKFBHH_01246 1.2e-28 C Aldo/keto reductase family
CIOKFBHH_01247 2.1e-75 C aldo keto reductase
CIOKFBHH_01248 2.7e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CIOKFBHH_01249 4.8e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIOKFBHH_01250 6.8e-269 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
CIOKFBHH_01251 1.8e-78 K 2 iron, 2 sulfur cluster binding
CIOKFBHH_01252 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CIOKFBHH_01253 1.2e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CIOKFBHH_01254 9.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
CIOKFBHH_01255 1e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CIOKFBHH_01256 7.2e-54 C FMN binding
CIOKFBHH_01257 6.8e-62 T His Kinase A (phosphoacceptor) domain
CIOKFBHH_01258 1e-48 T Transcriptional regulatory protein, C terminal
CIOKFBHH_01259 6.8e-16 S ABC-type transport system involved in multi-copper enzyme maturation permease component
CIOKFBHH_01260 9e-220 iscS 2.8.1.7 E Aminotransferase class V
CIOKFBHH_01262 1.6e-208 EGP Major facilitator Superfamily
CIOKFBHH_01263 2.7e-211 ycsG P Natural resistance-associated macrophage protein
CIOKFBHH_01264 2e-124 ycsF S LamB/YcsF family
CIOKFBHH_01265 2.2e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
CIOKFBHH_01266 4.8e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CIOKFBHH_01267 1.7e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
CIOKFBHH_01268 2.7e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
CIOKFBHH_01269 8.7e-72 K helix_turn_helix, mercury resistance
CIOKFBHH_01270 5.9e-82 S Psort location Cytoplasmic, score
CIOKFBHH_01271 1e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
CIOKFBHH_01272 1.1e-95 wecD K Acetyltransferase (GNAT) family
CIOKFBHH_01273 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
CIOKFBHH_01274 2.3e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
CIOKFBHH_01275 4.1e-214 2.1.1.14 E methionine synthase, vitamin-B12 independent
CIOKFBHH_01276 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CIOKFBHH_01277 3.5e-188 I Alpha beta
CIOKFBHH_01278 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
CIOKFBHH_01279 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CIOKFBHH_01281 7.2e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CIOKFBHH_01282 1.9e-149 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
CIOKFBHH_01283 2.4e-114 S Domain of unknown function (DUF4811)
CIOKFBHH_01284 4.7e-266 lmrB EGP Major facilitator Superfamily
CIOKFBHH_01285 1.9e-74 merR K MerR HTH family regulatory protein
CIOKFBHH_01286 4.4e-58
CIOKFBHH_01287 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CIOKFBHH_01288 6.9e-215 S CAAX protease self-immunity
CIOKFBHH_01289 8.1e-33 elaA S GNAT family
CIOKFBHH_01290 5.1e-207 yeaN P Transporter, major facilitator family protein
CIOKFBHH_01291 1.5e-74 S 3-demethylubiquinone-9 3-methyltransferase
CIOKFBHH_01292 9.2e-83 nrdI F Belongs to the NrdI family
CIOKFBHH_01293 3.6e-252 yhdP S Transporter associated domain
CIOKFBHH_01294 3e-90 GM epimerase
CIOKFBHH_01295 3.4e-86 M1-874 K Domain of unknown function (DUF1836)
CIOKFBHH_01296 9.8e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
CIOKFBHH_01297 6e-266 pipD E Dipeptidase
CIOKFBHH_01298 3.2e-130
CIOKFBHH_01299 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CIOKFBHH_01300 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
CIOKFBHH_01301 1.1e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
CIOKFBHH_01302 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
CIOKFBHH_01305 9.3e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
CIOKFBHH_01307 1.2e-226 glnP P ABC transporter
CIOKFBHH_01308 1.1e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIOKFBHH_01309 1e-251 cycA E Amino acid permease
CIOKFBHH_01310 4.3e-124 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIOKFBHH_01311 2.6e-255 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
CIOKFBHH_01312 2.8e-54 HA62_12640 S GCN5-related N-acetyl-transferase
CIOKFBHH_01313 1.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
CIOKFBHH_01314 5.6e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CIOKFBHH_01315 2.7e-205 yacL S domain protein
CIOKFBHH_01316 9.6e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CIOKFBHH_01317 8.6e-99 ywlG S Belongs to the UPF0340 family
CIOKFBHH_01318 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CIOKFBHH_01319 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CIOKFBHH_01320 1.5e-135 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CIOKFBHH_01321 1.1e-104 sigH K Belongs to the sigma-70 factor family
CIOKFBHH_01322 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CIOKFBHH_01323 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CIOKFBHH_01324 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
CIOKFBHH_01325 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CIOKFBHH_01326 5.7e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CIOKFBHH_01327 2.1e-38 L Transposase
CIOKFBHH_01328 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
CIOKFBHH_01329 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
CIOKFBHH_01330 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
CIOKFBHH_01331 3.4e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CIOKFBHH_01332 5.1e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CIOKFBHH_01333 1.7e-70 esbA S Family of unknown function (DUF5322)
CIOKFBHH_01334 1.5e-68 rnhA 3.1.26.4 L Ribonuclease HI
CIOKFBHH_01335 1.2e-106 XK27_02070 S Nitroreductase family
CIOKFBHH_01336 1e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
CIOKFBHH_01337 1.2e-118 yecS E ABC transporter permease
CIOKFBHH_01338 8.4e-22 M Glycosyltransferase like family 2
CIOKFBHH_01339 2.5e-129 I transferase activity, transferring acyl groups other than amino-acyl groups
CIOKFBHH_01341 6.3e-143 ET Bacterial periplasmic substrate-binding proteins
CIOKFBHH_01342 2.6e-157 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
CIOKFBHH_01343 1.5e-225 aadAT EK Aminotransferase, class I
CIOKFBHH_01344 3e-259 guaD 3.5.4.3 F Amidohydrolase family
CIOKFBHH_01345 4.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
CIOKFBHH_01348 2.9e-56 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
CIOKFBHH_01349 5.2e-74 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CIOKFBHH_01350 3.6e-49 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
CIOKFBHH_01357 3.3e-08
CIOKFBHH_01358 9e-98 S D5 N terminal like
CIOKFBHH_01359 1.7e-156 L DNA replication protein
CIOKFBHH_01362 2.5e-07 S Helix-turn-helix domain
CIOKFBHH_01363 8.2e-158 K Helix-turn-helix XRE-family like proteins
CIOKFBHH_01364 9.5e-195 L Belongs to the 'phage' integrase family
CIOKFBHH_01365 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CIOKFBHH_01366 1.1e-205 yfnA E Amino Acid
CIOKFBHH_01367 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
CIOKFBHH_01368 1.7e-105 gmk2 2.7.4.8 F Guanylate kinase
CIOKFBHH_01369 4e-83 zur P Belongs to the Fur family
CIOKFBHH_01371 6.3e-168
CIOKFBHH_01372 8.1e-188 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CIOKFBHH_01373 1.9e-92 K Transcriptional regulator (TetR family)
CIOKFBHH_01374 5.3e-207 V domain protein
CIOKFBHH_01375 1e-79 K FR47-like protein
CIOKFBHH_01376 7.8e-299 ybeC E amino acid
CIOKFBHH_01377 1.2e-134 pnuC H nicotinamide mononucleotide transporter
CIOKFBHH_01378 4.7e-210 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CIOKFBHH_01379 5e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CIOKFBHH_01380 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
CIOKFBHH_01381 4.3e-118 dedA S SNARE associated Golgi protein
CIOKFBHH_01382 0.0 helD 3.6.4.12 L DNA helicase
CIOKFBHH_01383 3.6e-160 EG EamA-like transporter family
CIOKFBHH_01384 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CIOKFBHH_01385 3.4e-135 IQ Dehydrogenase reductase
CIOKFBHH_01386 2.3e-104 2.3.1.128 K acetyltransferase
CIOKFBHH_01387 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
CIOKFBHH_01388 2.4e-130 sptS 2.7.13.3 T Histidine kinase
CIOKFBHH_01389 8e-80 K response regulator
CIOKFBHH_01390 9.2e-115 2.7.6.5 T Region found in RelA / SpoT proteins
CIOKFBHH_01391 5.7e-270 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CIOKFBHH_01392 0.0 norZ 1.7.2.5 P Cytochrome C and Quinol oxidase polypeptide I
CIOKFBHH_01393 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
CIOKFBHH_01394 7.5e-84
CIOKFBHH_01395 1.2e-105 S Domain of unknown function (DUF4767)
CIOKFBHH_01396 4.7e-54 K Helix-turn-helix domain
CIOKFBHH_01397 5.7e-172 1.3.1.9 S Nitronate monooxygenase
CIOKFBHH_01399 1.9e-67 rocF 3.5.3.1, 3.5.3.11 E Arginase family
CIOKFBHH_01400 1.4e-50 ybjQ S Belongs to the UPF0145 family
CIOKFBHH_01401 1.7e-224 dxs 2.2.1.7 HI 1-deoxy-D-xylulose-5-phosphate synthase
CIOKFBHH_01402 6.1e-123 bm3R1 K Bacterial regulatory proteins, tetR family
CIOKFBHH_01403 0.0 yhcA V ABC transporter, ATP-binding protein
CIOKFBHH_01404 7.5e-145 M Membrane
CIOKFBHH_01405 8.8e-24 XK27_06785 V ABC transporter
CIOKFBHH_01406 2.2e-102 K Transcriptional regulator
CIOKFBHH_01407 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CIOKFBHH_01408 2.1e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CIOKFBHH_01409 1.2e-260 argH 4.3.2.1 E argininosuccinate lyase
CIOKFBHH_01410 5e-13 lacA S transferase hexapeptide repeat
CIOKFBHH_01411 7.7e-157 L Thioesterase-like superfamily
CIOKFBHH_01413 1.8e-69 S NADPH-dependent FMN reductase
CIOKFBHH_01414 5.2e-241 yfnA E amino acid
CIOKFBHH_01415 9.7e-242 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CIOKFBHH_01417 5.3e-17 mleP3 S Membrane transport protein
CIOKFBHH_01420 2.9e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIOKFBHH_01421 2.2e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CIOKFBHH_01422 4.9e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CIOKFBHH_01423 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
CIOKFBHH_01424 1.6e-163 ubiB S ABC1 family
CIOKFBHH_01425 7.6e-127 ubiB S ABC1 family
CIOKFBHH_01426 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
CIOKFBHH_01427 2.3e-170 GK ROK family
CIOKFBHH_01428 1.1e-40
CIOKFBHH_01429 7.9e-79 copY K Copper transport repressor CopY TcrY
CIOKFBHH_01431 4.8e-54 L Belongs to the 'phage' integrase family
CIOKFBHH_01432 2.8e-16 lsgF M Glycosyl transferase family 2
CIOKFBHH_01433 6.3e-82 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIOKFBHH_01434 3.1e-51 M transferase activity, transferring glycosyl groups
CIOKFBHH_01435 5.8e-37 M transferase activity, transferring glycosyl groups
CIOKFBHH_01436 4.3e-21 tagF 2.7.8.12 M Glycosyltransferase like family 2
CIOKFBHH_01438 7.2e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIOKFBHH_01439 1.1e-49 tnp L MULE transposase domain
CIOKFBHH_01440 8.7e-19 cysE_1 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
CIOKFBHH_01441 1.2e-50 licD M LicD family
CIOKFBHH_01442 3.8e-213 nupG F Nucleoside transporter
CIOKFBHH_01443 2.2e-144 rihC 3.2.2.1 F Nucleoside
CIOKFBHH_01444 2.6e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
CIOKFBHH_01445 5.1e-157 noc K Belongs to the ParB family
CIOKFBHH_01446 2.3e-145 spo0J K Belongs to the ParB family
CIOKFBHH_01447 1.7e-30 yyzM S Bacterial protein of unknown function (DUF951)
CIOKFBHH_01448 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CIOKFBHH_01449 1.9e-133 XK27_01040 S Protein of unknown function (DUF1129)
CIOKFBHH_01450 9.5e-206 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CIOKFBHH_01451 6.3e-196 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
CIOKFBHH_01452 1.4e-181 C Zinc-binding dehydrogenase
CIOKFBHH_01453 3.1e-102 proW P ABC transporter, permease protein
CIOKFBHH_01454 3.6e-140 proV E ABC transporter, ATP-binding protein
CIOKFBHH_01455 1.8e-108 proWZ P ABC transporter permease
CIOKFBHH_01456 6.6e-162 proX M ABC transporter, substrate-binding protein, QAT family
CIOKFBHH_01457 1.5e-55 K Transcriptional regulator
CIOKFBHH_01458 4.2e-74 O OsmC-like protein
CIOKFBHH_01459 2e-73 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
CIOKFBHH_01460 1.4e-22 EGP Major Facilitator Superfamily
CIOKFBHH_01461 1.1e-96 L Probable transposase
CIOKFBHH_01462 1.1e-49 K TRANSCRIPTIONal
CIOKFBHH_01463 9.3e-189 V Abi-like protein
CIOKFBHH_01464 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
CIOKFBHH_01465 1.5e-59 hsdS 2.1.1.72, 3.1.21.3 V DNA specificity domain
CIOKFBHH_01466 1.9e-143 xerC L Belongs to the 'phage' integrase family
CIOKFBHH_01467 9.9e-58 3.1.21.3 V Type I restriction modification DNA specificity domain
CIOKFBHH_01468 8.6e-276 lacS G Transporter
CIOKFBHH_01469 0.0 rafA 3.2.1.22 G alpha-galactosidase
CIOKFBHH_01470 2.9e-182 galR K Transcriptional regulator
CIOKFBHH_01471 5.8e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CIOKFBHH_01472 1e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CIOKFBHH_01473 1.4e-281 yjeM E Amino Acid
CIOKFBHH_01474 1.7e-187 K helix_turn _helix lactose operon repressor
CIOKFBHH_01475 9.8e-261 G PTS system Galactitol-specific IIC component
CIOKFBHH_01476 3.2e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIOKFBHH_01477 1.1e-200 S Domain of unknown function (DUF4432)
CIOKFBHH_01478 9.8e-115 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CIOKFBHH_01479 8.8e-184 fruR3 K Transcriptional regulator, LacI family
CIOKFBHH_01480 5e-162 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
CIOKFBHH_01481 2.6e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIOKFBHH_01482 1e-56 trxA1 O Belongs to the thioredoxin family
CIOKFBHH_01483 1.5e-141 terC P membrane
CIOKFBHH_01484 9.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CIOKFBHH_01485 1e-170 corA P CorA-like Mg2+ transporter protein
CIOKFBHH_01486 8.4e-230 pbuX F xanthine permease
CIOKFBHH_01487 2e-61 rmeB K transcriptional regulator, MerR family
CIOKFBHH_01488 2.5e-133 ybbM S Uncharacterised protein family (UPF0014)
CIOKFBHH_01489 3.1e-41 ybbL S ABC transporter, ATP-binding protein
CIOKFBHH_01490 5.8e-58 ybbL S ABC transporter, ATP-binding protein
CIOKFBHH_01491 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CIOKFBHH_01492 0.0 N Uncharacterized conserved protein (DUF2075)
CIOKFBHH_01494 2.4e-101 K DNA-templated transcription, initiation
CIOKFBHH_01495 7e-124 K Crp-like helix-turn-helix domain
CIOKFBHH_01496 3.6e-241 larA 5.1.2.1 S Domain of unknown function (DUF2088)
CIOKFBHH_01497 1.7e-131 cpmA S AIR carboxylase
CIOKFBHH_01498 2.4e-216 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CIOKFBHH_01499 4.5e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CIOKFBHH_01500 1.7e-148 larE S NAD synthase
CIOKFBHH_01501 6.2e-185 hoxN U High-affinity nickel-transport protein
CIOKFBHH_01502 2.9e-81 tlpA2 L Transposase IS200 like
CIOKFBHH_01503 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
CIOKFBHH_01504 1.7e-88 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CIOKFBHH_01505 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CIOKFBHH_01506 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CIOKFBHH_01507 1.2e-74 rplI J Binds to the 23S rRNA
CIOKFBHH_01508 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CIOKFBHH_01509 1.4e-207 lmrP E Major Facilitator Superfamily
CIOKFBHH_01510 6.3e-50
CIOKFBHH_01511 2.2e-243 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CIOKFBHH_01512 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CIOKFBHH_01513 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
CIOKFBHH_01514 6.4e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CIOKFBHH_01515 4.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CIOKFBHH_01517 1.3e-11 S YjcQ protein
CIOKFBHH_01518 4.6e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CIOKFBHH_01519 2e-132 S Membrane
CIOKFBHH_01520 3.3e-76 4.4.1.5 E Glyoxalase
CIOKFBHH_01521 1.5e-85 yueI S Protein of unknown function (DUF1694)
CIOKFBHH_01522 2.9e-235 rarA L recombination factor protein RarA
CIOKFBHH_01524 6.8e-81 usp6 T universal stress protein
CIOKFBHH_01525 2.9e-151 2.3.1.19 K Helix-turn-helix XRE-family like proteins
CIOKFBHH_01526 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CIOKFBHH_01527 1.4e-181 S Protein of unknown function (DUF2785)
CIOKFBHH_01529 5.8e-222 rodA D Belongs to the SEDS family
CIOKFBHH_01530 7.9e-32 S Protein of unknown function (DUF2969)
CIOKFBHH_01531 7.7e-183 mbl D Cell shape determining protein MreB Mrl
CIOKFBHH_01532 1.8e-218 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
CIOKFBHH_01533 2.8e-29 S Protein of unknown function (DUF1146)
CIOKFBHH_01534 6.4e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CIOKFBHH_01535 4.4e-253 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CIOKFBHH_01536 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CIOKFBHH_01537 2.1e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CIOKFBHH_01538 7.4e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIOKFBHH_01539 1.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CIOKFBHH_01540 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CIOKFBHH_01541 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
CIOKFBHH_01542 5.4e-218 pyrP F Permease
CIOKFBHH_01543 1.5e-122 yibF S overlaps another CDS with the same product name
CIOKFBHH_01544 1.1e-182 yibE S overlaps another CDS with the same product name
CIOKFBHH_01545 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CIOKFBHH_01546 7e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CIOKFBHH_01547 2.3e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CIOKFBHH_01548 6.5e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CIOKFBHH_01549 2.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CIOKFBHH_01550 3.2e-109 tdk 2.7.1.21 F thymidine kinase
CIOKFBHH_01551 7.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
CIOKFBHH_01552 3.4e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
CIOKFBHH_01553 2.8e-48
CIOKFBHH_01554 1.7e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CIOKFBHH_01555 9.7e-194 ampC V Beta-lactamase
CIOKFBHH_01556 0.0 yfiC V ABC transporter
CIOKFBHH_01557 0.0 lmrA V ABC transporter, ATP-binding protein
CIOKFBHH_01558 1.8e-78 K Winged helix DNA-binding domain
CIOKFBHH_01559 2.3e-07
CIOKFBHH_01561 1e-56
CIOKFBHH_01563 7.4e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
CIOKFBHH_01564 6.3e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CIOKFBHH_01565 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
CIOKFBHH_01566 4.7e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
CIOKFBHH_01567 1.6e-85 K GNAT family
CIOKFBHH_01570 0.0 copB 3.6.3.4 P P-type ATPase
CIOKFBHH_01571 1.9e-74 K Copper transport repressor CopY TcrY
CIOKFBHH_01572 2.7e-76 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
CIOKFBHH_01573 9.1e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
CIOKFBHH_01574 1.7e-161 hrtB V ABC transporter permease
CIOKFBHH_01575 1.4e-72 crtB 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
CIOKFBHH_01576 4.1e-55 S SNARE associated Golgi protein
CIOKFBHH_01577 2.7e-238 N Uncharacterized conserved protein (DUF2075)
CIOKFBHH_01578 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CIOKFBHH_01580 2.3e-254 yifK E Amino acid permease
CIOKFBHH_01581 3.1e-93 P Cadmium resistance transporter
CIOKFBHH_01582 1e-73 ydzE EG EamA-like transporter family
CIOKFBHH_01583 2.2e-235 kgtP EGP Sugar (and other) transporter
CIOKFBHH_01584 1.1e-56
CIOKFBHH_01585 4.9e-159 xth 3.1.11.2 L exodeoxyribonuclease III
CIOKFBHH_01586 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CIOKFBHH_01587 1.4e-164 dprA LU DNA protecting protein DprA
CIOKFBHH_01588 2e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIOKFBHH_01589 1.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CIOKFBHH_01590 7.9e-84 L DNA integration
CIOKFBHH_01591 2.4e-198 gldA 1.1.1.6 C dehydrogenase
CIOKFBHH_01592 7.8e-120 IQ Enoyl-(Acyl carrier protein) reductase
CIOKFBHH_01593 1.5e-103 S Bacterial transferase hexapeptide (six repeats)
CIOKFBHH_01596 1e-188 EGP Major facilitator Superfamily
CIOKFBHH_01597 9.7e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CIOKFBHH_01598 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CIOKFBHH_01599 4.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CIOKFBHH_01602 6.1e-29 S Domain of unknown function (DUF4767)
CIOKFBHH_01603 5.4e-44 S Tautomerase enzyme
CIOKFBHH_01604 2.1e-22 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
CIOKFBHH_01605 7.8e-120 pnb C nitroreductase
CIOKFBHH_01606 3.2e-83 S Alpha/beta hydrolase family
CIOKFBHH_01607 1.2e-79 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CIOKFBHH_01608 6.2e-24 C reductase
CIOKFBHH_01609 7.7e-46 C Aldo keto reductase
CIOKFBHH_01613 1.4e-92 S Cupin superfamily (DUF985)
CIOKFBHH_01614 3.6e-123 K response regulator
CIOKFBHH_01615 2e-208 hpk31 2.7.13.3 T Histidine kinase
CIOKFBHH_01616 9.1e-205 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CIOKFBHH_01617 2.6e-139 azlC E AzlC protein
CIOKFBHH_01618 1.2e-60 azlD S branched-chain amino acid
CIOKFBHH_01619 1.2e-169 deoR K sugar-binding domain protein
CIOKFBHH_01620 2.5e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CIOKFBHH_01621 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CIOKFBHH_01622 2.7e-244 fucP G Major Facilitator Superfamily
CIOKFBHH_01623 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CIOKFBHH_01624 1.2e-73 IQ reductase
CIOKFBHH_01625 2e-240 treB G phosphotransferase system
CIOKFBHH_01626 1.5e-71 treR K UTRA
CIOKFBHH_01627 3.2e-239 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
CIOKFBHH_01628 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CIOKFBHH_01629 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
CIOKFBHH_01630 1.8e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
CIOKFBHH_01631 0.0 comEC S Competence protein ComEC
CIOKFBHH_01632 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
CIOKFBHH_01633 1.3e-90 comEA L Competence protein ComEA
CIOKFBHH_01634 6.7e-198 ylbL T Belongs to the peptidase S16 family
CIOKFBHH_01635 3.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CIOKFBHH_01636 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
CIOKFBHH_01637 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
CIOKFBHH_01638 3.5e-211 ftsW D Belongs to the SEDS family
CIOKFBHH_01639 0.0 typA T GTP-binding protein TypA
CIOKFBHH_01640 5.3e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
CIOKFBHH_01641 2.4e-49 yktA S Belongs to the UPF0223 family
CIOKFBHH_01642 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CIOKFBHH_01643 1.2e-74
CIOKFBHH_01644 2.2e-31 ykzG S Belongs to the UPF0356 family
CIOKFBHH_01645 9e-189 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
CIOKFBHH_01646 4.2e-74 spx4 1.20.4.1 P ArsC family
CIOKFBHH_01647 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIOKFBHH_01648 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CIOKFBHH_01649 7.1e-124 S Repeat protein
CIOKFBHH_01650 2.7e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
CIOKFBHH_01651 4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CIOKFBHH_01652 3e-306 S amidohydrolase
CIOKFBHH_01653 2.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CIOKFBHH_01654 2.2e-57 XK27_04120 S Putative amino acid metabolism
CIOKFBHH_01655 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CIOKFBHH_01657 7.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
CIOKFBHH_01658 1.2e-32 cspB K Cold shock protein
CIOKFBHH_01659 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CIOKFBHH_01661 4.8e-112 divIVA D DivIVA domain protein
CIOKFBHH_01662 2.9e-145 ylmH S S4 domain protein
CIOKFBHH_01663 6.8e-41 yggT S YGGT family
CIOKFBHH_01664 2.3e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CIOKFBHH_01665 4.5e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CIOKFBHH_01666 3.2e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CIOKFBHH_01667 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CIOKFBHH_01668 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CIOKFBHH_01669 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CIOKFBHH_01670 3.5e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CIOKFBHH_01671 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CIOKFBHH_01672 7e-09 ftsL D Cell division protein FtsL
CIOKFBHH_01673 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CIOKFBHH_01674 1.2e-79 mraZ K Belongs to the MraZ family
CIOKFBHH_01675 9.8e-58
CIOKFBHH_01676 1.2e-07 S Protein of unknown function (DUF4044)
CIOKFBHH_01677 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CIOKFBHH_01678 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CIOKFBHH_01679 8.2e-162 rrmA 2.1.1.187 H Methyltransferase
CIOKFBHH_01680 1.4e-195 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
CIOKFBHH_01681 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
CIOKFBHH_01682 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CIOKFBHH_01683 6e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
CIOKFBHH_01684 6.7e-113 yjbH Q Thioredoxin
CIOKFBHH_01685 9.4e-205 coiA 3.6.4.12 S Competence protein
CIOKFBHH_01686 4.5e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CIOKFBHH_01687 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CIOKFBHH_01688 3.5e-16 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
CIOKFBHH_01708 2.5e-79 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIOKFBHH_01709 1.9e-224 emrY EGP Major facilitator Superfamily
CIOKFBHH_01710 7.7e-171 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CIOKFBHH_01716 3e-29 bamA GM domain, Protein
CIOKFBHH_01717 1.2e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
CIOKFBHH_01718 9.7e-130 epsB M biosynthesis protein
CIOKFBHH_01719 1.8e-120 ywqD 2.7.10.1 D Capsular exopolysaccharide family
CIOKFBHH_01720 1.2e-143 ywqE 3.1.3.48 GM PHP domain protein
CIOKFBHH_01721 4.8e-131 cps2D 5.1.3.2 M RmlD substrate binding domain
CIOKFBHH_01722 3.6e-82 tuaA M Bacterial sugar transferase
CIOKFBHH_01723 3.2e-44 L Transposase and inactivated derivatives, IS30 family
CIOKFBHH_01724 9.2e-193 caiT U Belongs to the BCCT transporter (TC 2.A.15) family
CIOKFBHH_01725 1.5e-97 M Nucleotidyl transferase
CIOKFBHH_01726 8.2e-209 licA 2.7.1.89 M Nucleotidyl transferase
CIOKFBHH_01727 9.8e-82
CIOKFBHH_01728 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
CIOKFBHH_01729 5.6e-33 copZ P Heavy-metal-associated domain
CIOKFBHH_01730 1.6e-45 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
CIOKFBHH_01731 5.3e-113 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
CIOKFBHH_01732 1.5e-39 L Transposase
CIOKFBHH_01733 4.1e-41 L Probable transposase
CIOKFBHH_01734 3e-28 EGP Major Facilitator Superfamily
CIOKFBHH_01735 1.6e-44 EGP Major Facilitator Superfamily
CIOKFBHH_01736 1.6e-69 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
CIOKFBHH_01737 1.3e-56 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
CIOKFBHH_01738 3.5e-15 C Flavodoxin
CIOKFBHH_01739 4.3e-27 GM NmrA-like family
CIOKFBHH_01740 6.6e-19 S NAD(P)H dehydrogenase (quinone) activity
CIOKFBHH_01741 6.7e-107 L Integrase
CIOKFBHH_01742 6.1e-71 ydjP I Alpha/beta hydrolase family
CIOKFBHH_01743 8.7e-49 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CIOKFBHH_01744 6.7e-66 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CIOKFBHH_01745 9e-40 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
CIOKFBHH_01747 5.3e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
CIOKFBHH_01748 1.1e-152 yitU 3.1.3.104 S hydrolase
CIOKFBHH_01749 2.9e-74 K FR47-like protein
CIOKFBHH_01750 1.3e-73 tnpR L Resolvase, N terminal domain
CIOKFBHH_01751 2.3e-55 L PFAM transposase, IS4 family protein
CIOKFBHH_01752 1.5e-65 L PFAM transposase, IS4 family protein
CIOKFBHH_01753 1.2e-263 npr 1.11.1.1 C NADH oxidase
CIOKFBHH_01754 1.7e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CIOKFBHH_01755 2.6e-104 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
CIOKFBHH_01756 4.4e-71 yncA 2.3.1.79 S Maltose acetyltransferase
CIOKFBHH_01757 2.8e-74 S Fic/DOC family
CIOKFBHH_01758 2.5e-115 radC L DNA repair protein
CIOKFBHH_01759 1.9e-181 mreB D cell shape determining protein MreB
CIOKFBHH_01760 3.7e-146 mreC M Involved in formation and maintenance of cell shape
CIOKFBHH_01761 6.6e-93 mreD M rod shape-determining protein MreD
CIOKFBHH_01762 1.4e-108 glnP P ABC transporter permease
CIOKFBHH_01763 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
CIOKFBHH_01764 2.4e-161 aatB ET ABC transporter substrate-binding protein
CIOKFBHH_01765 1.5e-231 ymfF S Peptidase M16 inactive domain protein
CIOKFBHH_01766 5.8e-252 ymfH S Peptidase M16
CIOKFBHH_01767 1.8e-96 ymfM S Helix-turn-helix domain
CIOKFBHH_01768 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CIOKFBHH_01769 1.9e-231 cinA 3.5.1.42 S Belongs to the CinA family
CIOKFBHH_01770 2.2e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CIOKFBHH_01771 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
CIOKFBHH_01772 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CIOKFBHH_01773 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CIOKFBHH_01774 1.9e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CIOKFBHH_01775 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CIOKFBHH_01776 1.1e-175 2.4.2.29 F queuine tRNA-ribosyltransferase activity
CIOKFBHH_01777 1.6e-41 yajC U Preprotein translocase
CIOKFBHH_01778 6.8e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
CIOKFBHH_01779 6.4e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CIOKFBHH_01780 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CIOKFBHH_01781 1.2e-42 yrzL S Belongs to the UPF0297 family
CIOKFBHH_01782 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CIOKFBHH_01783 5.7e-33 yrzB S Belongs to the UPF0473 family
CIOKFBHH_01784 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CIOKFBHH_01785 4.7e-91 cvpA S Colicin V production protein
CIOKFBHH_01786 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CIOKFBHH_01787 1e-53 trxA O Belongs to the thioredoxin family
CIOKFBHH_01788 7.7e-225 clcA_2 P Chloride transporter, ClC family
CIOKFBHH_01789 3e-93 yslB S Protein of unknown function (DUF2507)
CIOKFBHH_01790 5.4e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CIOKFBHH_01791 1.1e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CIOKFBHH_01792 8.8e-95 S Phosphoesterase
CIOKFBHH_01793 4.9e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
CIOKFBHH_01794 2e-155 ykuT M mechanosensitive ion channel
CIOKFBHH_01795 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CIOKFBHH_01796 4.9e-70
CIOKFBHH_01797 4.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
CIOKFBHH_01798 2.2e-185 ccpA K catabolite control protein A
CIOKFBHH_01799 3.6e-85
CIOKFBHH_01800 3.7e-134 yebC K Transcriptional regulatory protein
CIOKFBHH_01801 4.9e-84 mltD CBM50 M PFAM NLP P60 protein
CIOKFBHH_01802 2.1e-159 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
CIOKFBHH_01803 8.8e-68 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
CIOKFBHH_01804 2.7e-177 comGA NU Type II IV secretion system protein
CIOKFBHH_01805 3.5e-159 comGB NU type II secretion system
CIOKFBHH_01806 1.1e-47 comGC U competence protein ComGC
CIOKFBHH_01807 2.3e-15 NU general secretion pathway protein
CIOKFBHH_01809 2.9e-14
CIOKFBHH_01811 1.1e-158 ytxK 2.1.1.72 L N-6 DNA Methylase
CIOKFBHH_01812 2.8e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CIOKFBHH_01813 1e-108 S Calcineurin-like phosphoesterase
CIOKFBHH_01814 1.2e-97 yutD S Protein of unknown function (DUF1027)
CIOKFBHH_01815 6.6e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CIOKFBHH_01816 7.5e-25 S Protein of unknown function (DUF1461)
CIOKFBHH_01817 2.9e-103 dedA S SNARE-like domain protein
CIOKFBHH_01818 1e-80 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CIOKFBHH_01819 5.6e-72 L PFAM Integrase catalytic region
CIOKFBHH_01820 1.2e-97 rfbX S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CIOKFBHH_01821 2.3e-83 lacR K Transcriptional regulator
CIOKFBHH_01822 8.1e-218 lacS G Transporter
CIOKFBHH_01823 3.3e-119 mleP3 S Membrane transport protein
CIOKFBHH_01824 1.1e-52 trxA O Belongs to the thioredoxin family
CIOKFBHH_01825 1.1e-253 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
CIOKFBHH_01826 6.1e-209 EG GntP family permease
CIOKFBHH_01827 2.3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CIOKFBHH_01828 4.5e-17 xre K Helix-turn-helix domain
CIOKFBHH_01829 2.1e-51 S Sugar efflux transporter for intercellular exchange
CIOKFBHH_01830 8.9e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
CIOKFBHH_01831 2.1e-45 S Protein conserved in bacteria
CIOKFBHH_01832 2.2e-96 ywrO S Flavodoxin-like fold
CIOKFBHH_01833 9.8e-77
CIOKFBHH_01834 0.0 trxB2 1.8.1.9 C Thioredoxin domain
CIOKFBHH_01835 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
CIOKFBHH_01840 1.1e-09 L Terminase small subunit
CIOKFBHH_01842 1.5e-149 L Transposase and inactivated derivatives, IS30 family
CIOKFBHH_01843 3.1e-185 ybiR P Citrate transporter
CIOKFBHH_01844 1.7e-84 usp1 T Belongs to the universal stress protein A family
CIOKFBHH_01845 5.4e-108 S VIT family
CIOKFBHH_01846 1.1e-111 S membrane
CIOKFBHH_01847 3.7e-16 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CIOKFBHH_01848 1.1e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CIOKFBHH_01849 1.5e-178 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CIOKFBHH_01850 6.5e-262 lysC 2.7.2.4 E Belongs to the aspartokinase family
CIOKFBHH_01851 2.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CIOKFBHH_01852 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CIOKFBHH_01853 4.7e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CIOKFBHH_01854 9.2e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIOKFBHH_01855 8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CIOKFBHH_01856 2.9e-218 patA 2.6.1.1 E Aminotransferase
CIOKFBHH_01857 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CIOKFBHH_01858 1.9e-226 ktrB P Potassium uptake protein
CIOKFBHH_01859 7.5e-118 ktrA P domain protein
CIOKFBHH_01860 1.2e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
CIOKFBHH_01861 1.7e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CIOKFBHH_01862 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CIOKFBHH_01864 0.0 dnaE 2.7.7.7 L DNA polymerase
CIOKFBHH_01865 2.4e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CIOKFBHH_01866 1.8e-167 cvfB S S1 domain
CIOKFBHH_01867 2.4e-132 xerD D recombinase XerD
CIOKFBHH_01868 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CIOKFBHH_01869 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CIOKFBHH_01870 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CIOKFBHH_01871 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CIOKFBHH_01872 6.9e-80 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CIOKFBHH_01873 1.3e-198 ypbB 5.1.3.1 S Helix-turn-helix domain
CIOKFBHH_01874 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
CIOKFBHH_01875 9.7e-31 M Lysin motif
CIOKFBHH_01876 5.8e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CIOKFBHH_01877 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
CIOKFBHH_01878 1.7e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CIOKFBHH_01879 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CIOKFBHH_01880 1.8e-234 S Tetratricopeptide repeat protein
CIOKFBHH_01881 4.7e-165 xerD L Phage integrase, N-terminal SAM-like domain
CIOKFBHH_01882 2.4e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CIOKFBHH_01883 0.0 yfmR S ABC transporter, ATP-binding protein
CIOKFBHH_01884 6.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CIOKFBHH_01885 8.7e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CIOKFBHH_01886 1.2e-109 hlyIII S protein, hemolysin III
CIOKFBHH_01887 2.4e-153 DegV S EDD domain protein, DegV family
CIOKFBHH_01888 2.9e-218 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
CIOKFBHH_01889 3.2e-107 cat S Bacterial transferase hexapeptide (six repeats)
CIOKFBHH_01890 1.1e-167 ypmR E lipolytic protein G-D-S-L family
CIOKFBHH_01891 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
CIOKFBHH_01892 3.1e-36 yozE S Belongs to the UPF0346 family
CIOKFBHH_01893 2.2e-86
CIOKFBHH_01894 1e-69 S Asp23 family, cell envelope-related function
CIOKFBHH_01895 6e-12 S Transglycosylase associated protein
CIOKFBHH_01896 3.8e-16
CIOKFBHH_01897 3.5e-87 galR K Transcriptional regulator
CIOKFBHH_01898 2e-83 glcU U sugar transport
CIOKFBHH_01899 1.3e-30 cspA K Cold shock protein
CIOKFBHH_01900 3.4e-123 sirR K iron dependent repressor
CIOKFBHH_01901 6e-163 czcD P cation diffusion facilitator family transporter
CIOKFBHH_01902 6.9e-33 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CIOKFBHH_01903 4e-69 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CIOKFBHH_01904 1.4e-56 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
CIOKFBHH_01905 1e-38 mdt(A) EGP Major facilitator Superfamily
CIOKFBHH_01906 6.1e-120 L hmm pf00665
CIOKFBHH_01907 2.5e-75 S Core-2/I-Branching enzyme
CIOKFBHH_01908 1.6e-90 S PAS domain
CIOKFBHH_01909 9.5e-72 macB_3 V FtsX-like permease family
CIOKFBHH_01910 8.3e-51 L Helix-turn-helix domain
CIOKFBHH_01911 6.2e-85 L hmm pf00665
CIOKFBHH_01912 3.8e-85 macB_3 V FtsX-like permease family
CIOKFBHH_01913 2.9e-85 macB_3 V FtsX-like permease family
CIOKFBHH_01914 2.6e-133 L PFAM transposase, IS4 family protein
CIOKFBHH_01915 7.6e-180 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CIOKFBHH_01916 3.5e-65 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
CIOKFBHH_01917 1.9e-66 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
CIOKFBHH_01918 4.3e-41 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
CIOKFBHH_01921 4.1e-122 arcC 2.7.2.2 E Amino acid kinase family
CIOKFBHH_01922 1.3e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
CIOKFBHH_01923 8.8e-124 C nitroreductase
CIOKFBHH_01924 2.3e-136 E GDSL-like Lipase/Acylhydrolase family
CIOKFBHH_01925 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
CIOKFBHH_01926 5.6e-197 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
CIOKFBHH_01927 0.0 pepN 3.4.11.2 E aminopeptidase
CIOKFBHH_01928 1.4e-62 morA C Aldo keto reductase
CIOKFBHH_01929 5.8e-166 K Transcriptional regulator
CIOKFBHH_01930 1.3e-24 phaG GT1 I carboxylic ester hydrolase activity
CIOKFBHH_01931 7.9e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CIOKFBHH_01933 4.3e-155 metQ_4 P Belongs to the nlpA lipoprotein family
CIOKFBHH_01934 4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CIOKFBHH_01935 0.0 helD 3.6.4.12 L DNA helicase
CIOKFBHH_01936 6.6e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
CIOKFBHH_01937 6.8e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CIOKFBHH_01938 3.2e-186
CIOKFBHH_01939 1.3e-128 cobB K SIR2 family
CIOKFBHH_01940 5.3e-212 norA EGP Major facilitator Superfamily
CIOKFBHH_01941 9.5e-163 yunF F Protein of unknown function DUF72
CIOKFBHH_01942 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CIOKFBHH_01943 1.8e-147 tatD L hydrolase, TatD family
CIOKFBHH_01944 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CIOKFBHH_01945 9.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CIOKFBHH_01946 3.8e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CIOKFBHH_01947 1.5e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
CIOKFBHH_01948 5.4e-95 fhuC P ABC transporter
CIOKFBHH_01949 2.1e-127 znuB U ABC 3 transport family
CIOKFBHH_01950 2.4e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CIOKFBHH_01951 3.6e-204 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CIOKFBHH_01952 3.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CIOKFBHH_01953 3e-32
CIOKFBHH_01954 1.4e-142 yxeH S hydrolase
CIOKFBHH_01955 5.7e-266 ywfO S HD domain protein
CIOKFBHH_01956 3.2e-74 ywiB S Domain of unknown function (DUF1934)
CIOKFBHH_01957 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CIOKFBHH_01958 1.1e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CIOKFBHH_01959 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CIOKFBHH_01960 6e-41 rpmE2 J Ribosomal protein L31
CIOKFBHH_01961 3.3e-29 mdtG EGP Major facilitator Superfamily
CIOKFBHH_01962 4.7e-123 srtA 3.4.22.70 M sortase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)