ORF_ID e_value Gene_name EC_number CAZy COGs Description
DONFEKIO_00001 1.8e-17 2.1.1.72 LV Eco57I restriction-modification methylase
DONFEKIO_00002 4e-202 L SNF2 family N-terminal domain
DONFEKIO_00003 4.8e-293 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DONFEKIO_00004 1.9e-212 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
DONFEKIO_00005 1.5e-118 ywlC 2.7.7.87 J Belongs to the SUA5 family
DONFEKIO_00006 6.6e-125 livF E ATPases associated with a variety of cellular activities
DONFEKIO_00007 1.4e-161 E Branched-chain amino acid ATP-binding cassette transporter
DONFEKIO_00008 1.7e-188 livM U Belongs to the binding-protein-dependent transport system permease family
DONFEKIO_00009 3.5e-110 U Belongs to the binding-protein-dependent transport system permease family
DONFEKIO_00010 8.9e-207 livK E Receptor family ligand binding region
DONFEKIO_00011 8.2e-165 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DONFEKIO_00012 3.7e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DONFEKIO_00013 1.3e-36 rpmE J Binds the 23S rRNA
DONFEKIO_00015 1.1e-84 yebQ EGP Major facilitator Superfamily
DONFEKIO_00016 7.1e-152
DONFEKIO_00017 3.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DONFEKIO_00018 2.5e-163 dkgB S Oxidoreductase, aldo keto reductase family protein
DONFEKIO_00019 4.3e-16 EGP Major facilitator superfamily
DONFEKIO_00020 1.2e-86 K Winged helix DNA-binding domain
DONFEKIO_00021 5.3e-178 glkA 2.7.1.2 G ROK family
DONFEKIO_00023 7.7e-308 EGP Major Facilitator Superfamily
DONFEKIO_00024 0.0 yjjK S ATP-binding cassette protein, ChvD family
DONFEKIO_00025 5.6e-169 tesB I Thioesterase-like superfamily
DONFEKIO_00026 3.5e-86 S Protein of unknown function (DUF3180)
DONFEKIO_00027 6.5e-226 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DONFEKIO_00028 6.4e-162 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DONFEKIO_00029 1.1e-96 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
DONFEKIO_00030 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DONFEKIO_00031 2.7e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DONFEKIO_00032 4.4e-211 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DONFEKIO_00033 2.2e-250 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
DONFEKIO_00034 9e-298
DONFEKIO_00035 1.5e-189 natA V ATPases associated with a variety of cellular activities
DONFEKIO_00036 4.7e-235 epsG M Glycosyl transferase family 21
DONFEKIO_00037 1.9e-281 S AI-2E family transporter
DONFEKIO_00038 2.3e-178 3.4.14.13 M Glycosyltransferase like family 2
DONFEKIO_00039 5.2e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
DONFEKIO_00040 1.6e-262 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
DONFEKIO_00043 2.9e-160 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DONFEKIO_00045 2.1e-15 int8 L Phage integrase family
DONFEKIO_00046 1.5e-12 sprF 4.6.1.1 M Cell surface antigen C-terminus
DONFEKIO_00047 1.9e-267 lacS G Psort location CytoplasmicMembrane, score 10.00
DONFEKIO_00048 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DONFEKIO_00049 4.8e-185 lacR K Transcriptional regulator, LacI family
DONFEKIO_00050 2e-20 L Helix-turn-helix domain
DONFEKIO_00051 4e-248 G Bacterial extracellular solute-binding protein
DONFEKIO_00052 7.9e-216 GK ROK family
DONFEKIO_00053 0.0 G Glycosyl hydrolase family 20, domain 2
DONFEKIO_00054 5e-09 L HTH-like domain
DONFEKIO_00055 8.9e-219 vex3 V ABC transporter permease
DONFEKIO_00056 4e-210 vex1 V Efflux ABC transporter, permease protein
DONFEKIO_00057 4.1e-110 vex2 V ABC transporter, ATP-binding protein
DONFEKIO_00058 7.7e-97 ptpA 3.1.3.48 T low molecular weight
DONFEKIO_00059 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
DONFEKIO_00060 1e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DONFEKIO_00061 7.7e-73 attW O OsmC-like protein
DONFEKIO_00062 1.5e-189 T Universal stress protein family
DONFEKIO_00063 3e-104 M NlpC/P60 family
DONFEKIO_00064 2.9e-99 M NlpC/P60 family
DONFEKIO_00065 1.7e-168 usp 3.5.1.28 CBM50 S CHAP domain
DONFEKIO_00066 5.7e-211 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DONFEKIO_00067 1.8e-32
DONFEKIO_00068 2.7e-174 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DONFEKIO_00069 5.4e-116 phoU P Plays a role in the regulation of phosphate uptake
DONFEKIO_00070 1.1e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DONFEKIO_00071 7.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
DONFEKIO_00072 2.3e-311 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DONFEKIO_00074 1.3e-218 araJ EGP Major facilitator Superfamily
DONFEKIO_00075 0.0 S Domain of unknown function (DUF4037)
DONFEKIO_00076 1.6e-117 S Protein of unknown function (DUF4125)
DONFEKIO_00077 0.0 S alpha beta
DONFEKIO_00078 3.7e-67
DONFEKIO_00079 4.2e-287 pspC KT PspC domain
DONFEKIO_00080 1.1e-237 tcsS3 KT PspC domain
DONFEKIO_00081 4.4e-118 degU K helix_turn_helix, Lux Regulon
DONFEKIO_00082 4.1e-168 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DONFEKIO_00083 3.4e-205 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
DONFEKIO_00084 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
DONFEKIO_00085 2.5e-167 G ABC transporter permease
DONFEKIO_00086 6.9e-173 malC G Binding-protein-dependent transport system inner membrane component
DONFEKIO_00087 1.2e-249 G Bacterial extracellular solute-binding protein
DONFEKIO_00089 1.1e-242 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DONFEKIO_00090 4.4e-182 I Diacylglycerol kinase catalytic domain
DONFEKIO_00091 2.5e-153 arbG K CAT RNA binding domain
DONFEKIO_00092 0.0 crr 2.7.1.193 G pts system, glucose-specific IIABC component
DONFEKIO_00093 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
DONFEKIO_00094 4e-198 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DONFEKIO_00095 3.6e-73 K Transcriptional regulator
DONFEKIO_00096 9.4e-278 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DONFEKIO_00097 2e-173 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DONFEKIO_00098 9.1e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DONFEKIO_00100 1.6e-98
DONFEKIO_00101 3.6e-261 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DONFEKIO_00102 2.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
DONFEKIO_00103 7e-220 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DONFEKIO_00104 4.8e-82 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DONFEKIO_00105 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DONFEKIO_00106 1.5e-189 nusA K Participates in both transcription termination and antitermination
DONFEKIO_00107 1.4e-125
DONFEKIO_00108 2.2e-100 K helix_turn _helix lactose operon repressor
DONFEKIO_00110 3.2e-152 E Transglutaminase/protease-like homologues
DONFEKIO_00111 0.0 gcs2 S A circularly permuted ATPgrasp
DONFEKIO_00112 8.7e-170 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DONFEKIO_00113 7.4e-60 rplQ J Ribosomal protein L17
DONFEKIO_00114 3.4e-183 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DONFEKIO_00115 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DONFEKIO_00116 1.2e-61 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DONFEKIO_00117 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DONFEKIO_00118 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DONFEKIO_00119 2.2e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DONFEKIO_00120 6.9e-248 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DONFEKIO_00121 8.1e-76 rplO J binds to the 23S rRNA
DONFEKIO_00122 7e-26 rpmD J Ribosomal protein L30p/L7e
DONFEKIO_00123 6.7e-96 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DONFEKIO_00124 2.4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DONFEKIO_00125 5.4e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DONFEKIO_00126 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DONFEKIO_00127 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DONFEKIO_00128 4.4e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DONFEKIO_00129 1.3e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DONFEKIO_00130 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DONFEKIO_00131 6.4e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DONFEKIO_00132 4.1e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
DONFEKIO_00133 2.2e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DONFEKIO_00134 1.7e-100 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DONFEKIO_00135 9.7e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DONFEKIO_00136 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DONFEKIO_00137 1.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DONFEKIO_00138 7.5e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DONFEKIO_00139 3.1e-116 rplD J Forms part of the polypeptide exit tunnel
DONFEKIO_00140 8.7e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DONFEKIO_00141 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
DONFEKIO_00142 8.2e-137 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
DONFEKIO_00143 7.8e-147 ywiC S YwiC-like protein
DONFEKIO_00144 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DONFEKIO_00145 3.5e-224 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
DONFEKIO_00146 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DONFEKIO_00147 3.7e-82 rpsI J Belongs to the universal ribosomal protein uS9 family
DONFEKIO_00148 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DONFEKIO_00149 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
DONFEKIO_00150 8.4e-117
DONFEKIO_00151 3.4e-112 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
DONFEKIO_00152 6.3e-185 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DONFEKIO_00153 2e-116 M Bacterial capsule synthesis protein PGA_cap
DONFEKIO_00154 6.3e-245 bglA 3.2.1.21 G Glycosyl hydrolase family 1
DONFEKIO_00155 6.1e-160 U Binding-protein-dependent transport system inner membrane component
DONFEKIO_00156 1.2e-163 malC U Binding-protein-dependent transport system inner membrane component
DONFEKIO_00157 1.3e-243 malE G Bacterial extracellular solute-binding protein
DONFEKIO_00158 1.2e-216 rbsR K helix_turn _helix lactose operon repressor
DONFEKIO_00159 5.2e-22
DONFEKIO_00161 3.8e-62 S EamA-like transporter family
DONFEKIO_00162 2.5e-20 S EamA-like transporter family
DONFEKIO_00163 1.4e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DONFEKIO_00164 6.1e-224 dapC E Aminotransferase class I and II
DONFEKIO_00165 2.9e-59 fdxA C 4Fe-4S binding domain
DONFEKIO_00166 1.2e-269 E aromatic amino acid transport protein AroP K03293
DONFEKIO_00167 1.9e-220 murB 1.3.1.98 M Cell wall formation
DONFEKIO_00168 4.1e-25 rpmG J Ribosomal protein L33
DONFEKIO_00172 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DONFEKIO_00173 2.9e-133
DONFEKIO_00174 2.6e-85 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
DONFEKIO_00175 9.5e-56 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
DONFEKIO_00176 4.3e-31 fmdB S Putative regulatory protein
DONFEKIO_00177 2.3e-105 flgA NO SAF
DONFEKIO_00178 4.8e-28 L Superfamily I DNA and RNA helicases and helicase subunits
DONFEKIO_00179 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
DONFEKIO_00180 8.9e-192 T Forkhead associated domain
DONFEKIO_00181 9.3e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DONFEKIO_00182 2.4e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DONFEKIO_00183 9.9e-146 3.2.1.8 S alpha beta
DONFEKIO_00184 1.1e-251 pbuO S Permease family
DONFEKIO_00185 2.1e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DONFEKIO_00186 1.3e-171 pstA P Phosphate transport system permease
DONFEKIO_00187 1.2e-156 pstC P probably responsible for the translocation of the substrate across the membrane
DONFEKIO_00188 1.3e-202 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
DONFEKIO_00189 3.8e-142 KT Transcriptional regulatory protein, C terminal
DONFEKIO_00190 3.9e-208 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
DONFEKIO_00191 1.8e-240 EGP Sugar (and other) transporter
DONFEKIO_00192 5.7e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DONFEKIO_00193 1.9e-236 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DONFEKIO_00194 3.4e-216 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DONFEKIO_00195 3.9e-267 pepC 3.4.22.40 E Peptidase C1-like family
DONFEKIO_00196 3.6e-45 D nuclear chromosome segregation
DONFEKIO_00197 1.7e-125 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DONFEKIO_00198 8.4e-151 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DONFEKIO_00199 5.7e-197 yfiH Q Multi-copper polyphenol oxidoreductase laccase
DONFEKIO_00200 1e-303 yegQ O Peptidase family U32 C-terminal domain
DONFEKIO_00201 6.3e-179 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DONFEKIO_00202 7.7e-103 rsmD 2.1.1.171 L Conserved hypothetical protein 95
DONFEKIO_00203 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
DONFEKIO_00204 2.5e-29 rpmB J Ribosomal L28 family
DONFEKIO_00205 3.2e-197 yegV G pfkB family carbohydrate kinase
DONFEKIO_00206 2.5e-239 yxiO S Vacuole effluxer Atg22 like
DONFEKIO_00207 3.7e-82 soxR K helix_turn_helix, mercury resistance
DONFEKIO_00208 1.2e-61 T Toxic component of a toxin-antitoxin (TA) module
DONFEKIO_00209 8.1e-54 relB L RelB antitoxin
DONFEKIO_00210 1.3e-23 yxiO G Major facilitator Superfamily
DONFEKIO_00211 1.5e-181 K Helix-turn-helix XRE-family like proteins
DONFEKIO_00212 1.2e-19
DONFEKIO_00213 2.8e-114 S Alpha/beta hydrolase family
DONFEKIO_00217 1.9e-17 EGP Major facilitator Superfamily
DONFEKIO_00218 2e-55 XK27_04590 S NADPH-dependent FMN reductase
DONFEKIO_00220 4.5e-294 pccB I Carboxyl transferase domain
DONFEKIO_00221 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
DONFEKIO_00222 2.2e-92 bioY S BioY family
DONFEKIO_00223 1.4e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
DONFEKIO_00224 0.0
DONFEKIO_00225 2.2e-165 QT PucR C-terminal helix-turn-helix domain
DONFEKIO_00226 2.7e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DONFEKIO_00227 1e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DONFEKIO_00228 2.5e-146 K Psort location Cytoplasmic, score
DONFEKIO_00229 1.4e-110 nusG K Participates in transcription elongation, termination and antitermination
DONFEKIO_00230 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DONFEKIO_00232 1.2e-227 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
DONFEKIO_00233 1.7e-219 G polysaccharide deacetylase
DONFEKIO_00234 8.3e-199 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DONFEKIO_00235 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DONFEKIO_00236 5.8e-39 rpmA J Ribosomal L27 protein
DONFEKIO_00237 1.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
DONFEKIO_00238 0.0 rne 3.1.26.12 J Ribonuclease E/G family
DONFEKIO_00239 1.6e-232 dapE 3.5.1.18 E Peptidase dimerisation domain
DONFEKIO_00240 5.5e-167 mdcF S Transporter, auxin efflux carrier (AEC) family protein
DONFEKIO_00241 5.7e-166 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
DONFEKIO_00242 3.2e-149 S Amidohydrolase
DONFEKIO_00243 5.4e-202 fucP G Major Facilitator Superfamily
DONFEKIO_00244 2.8e-148 IQ KR domain
DONFEKIO_00245 1.1e-250 4.2.1.68 M Enolase C-terminal domain-like
DONFEKIO_00246 3.5e-191 K Bacterial regulatory proteins, lacI family
DONFEKIO_00247 3.7e-255 V Efflux ABC transporter, permease protein
DONFEKIO_00248 3.3e-138 V ATPases associated with a variety of cellular activities
DONFEKIO_00249 1.6e-28 S Protein of unknown function (DUF1778)
DONFEKIO_00250 2e-91 K Acetyltransferase (GNAT) family
DONFEKIO_00251 1.7e-276 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
DONFEKIO_00252 2.7e-184 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DONFEKIO_00253 2.8e-238 hom 1.1.1.3 E Homoserine dehydrogenase
DONFEKIO_00254 5.6e-54 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
DONFEKIO_00255 3e-55 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DONFEKIO_00256 1.7e-301 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DONFEKIO_00257 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DONFEKIO_00258 8.1e-131 K Bacterial regulatory proteins, tetR family
DONFEKIO_00259 3.1e-193 G Transmembrane secretion effector
DONFEKIO_00260 2.5e-18 G Transmembrane secretion effector
DONFEKIO_00261 6.8e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DONFEKIO_00262 5.3e-256 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
DONFEKIO_00263 2.1e-157 ET Bacterial periplasmic substrate-binding proteins
DONFEKIO_00264 3.7e-120 ytmL P Binding-protein-dependent transport system inner membrane component
DONFEKIO_00265 3.6e-140 P Binding-protein-dependent transport system inner membrane component
DONFEKIO_00266 1.3e-104 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
DONFEKIO_00267 3.5e-132 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
DONFEKIO_00268 1.8e-220 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
DONFEKIO_00269 2.2e-21 2.7.13.3 T Histidine kinase
DONFEKIO_00270 1.3e-17 S Bacterial PH domain
DONFEKIO_00271 1.4e-132 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DONFEKIO_00272 1.3e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DONFEKIO_00273 1.7e-140 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
DONFEKIO_00274 8.4e-262 S Calcineurin-like phosphoesterase
DONFEKIO_00275 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DONFEKIO_00276 9.2e-235 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
DONFEKIO_00277 8.5e-132
DONFEKIO_00278 0.0 G N-terminal domain of (some) glycogen debranching enzymes
DONFEKIO_00279 2.7e-139 P Binding-protein-dependent transport system inner membrane component
DONFEKIO_00280 2.2e-208 U Binding-protein-dependent transport system inner membrane component
DONFEKIO_00281 2.9e-208 G Bacterial extracellular solute-binding protein
DONFEKIO_00282 5e-129 K helix_turn _helix lactose operon repressor
DONFEKIO_00283 3.9e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DONFEKIO_00284 2.8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DONFEKIO_00285 2.6e-216 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DONFEKIO_00286 1.5e-216 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
DONFEKIO_00288 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DONFEKIO_00289 6.2e-163 S Auxin Efflux Carrier
DONFEKIO_00290 1.8e-158 fahA Q Fumarylacetoacetate (FAA) hydrolase family
DONFEKIO_00291 8.3e-107 S Domain of unknown function (DUF4190)
DONFEKIO_00292 5.7e-161
DONFEKIO_00293 3e-234 glf 5.4.99.9 M UDP-galactopyranose mutase
DONFEKIO_00294 5.5e-45 5.3.1.27 G sugar phosphate isomerase involved in capsule formation
DONFEKIO_00295 2.2e-58 G Branched-chain amino acid transport system / permease component
DONFEKIO_00296 7.3e-72 P branched-chain amino acid ABC transporter, permease protein
DONFEKIO_00297 6.3e-120 G ATPases associated with a variety of cellular activities
DONFEKIO_00298 2.1e-79 G ABC-type sugar transport system periplasmic component
DONFEKIO_00299 3e-167 xylB 1.1.1.57, 2.7.1.17 G Belongs to the FGGY kinase family
DONFEKIO_00300 1e-75 xylR GK ROK family
DONFEKIO_00301 8.7e-37
DONFEKIO_00302 4.2e-200 M Glycosyltransferase like family 2
DONFEKIO_00303 7.8e-183 S Predicted membrane protein (DUF2142)
DONFEKIO_00304 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DONFEKIO_00305 0.0 GT2,GT4 M Glycosyl transferase family 2
DONFEKIO_00306 1.1e-164 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
DONFEKIO_00307 1.4e-118 rgpC U Transport permease protein
DONFEKIO_00308 4.7e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DONFEKIO_00309 4.6e-290 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DONFEKIO_00310 1.3e-206 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DONFEKIO_00311 0.0
DONFEKIO_00312 4.3e-167 rfbJ M Glycosyl transferase family 2
DONFEKIO_00313 4.8e-22 M nuclease
DONFEKIO_00314 3.8e-67 M L,D-transpeptidase catalytic domain
DONFEKIO_00315 4.1e-163 lytC 3.1.4.46, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
DONFEKIO_00316 3.8e-225 K Cell envelope-related transcriptional attenuator domain
DONFEKIO_00317 1.2e-261 V ABC transporter permease
DONFEKIO_00318 1.2e-184 V ABC transporter
DONFEKIO_00319 3.1e-144 T HD domain
DONFEKIO_00320 7.9e-160 S Glutamine amidotransferase domain
DONFEKIO_00321 0.0 kup P Transport of potassium into the cell
DONFEKIO_00322 8.3e-187 tatD L TatD related DNase
DONFEKIO_00323 0.0 yknV V ABC transporter
DONFEKIO_00324 0.0 mdlA2 V ABC transporter
DONFEKIO_00325 2.3e-23 S ATPase domain predominantly from Archaea
DONFEKIO_00326 7e-253 S Domain of unknown function (DUF4143)
DONFEKIO_00327 3e-194 G Glycosyl hydrolases family 43
DONFEKIO_00328 1.1e-153 U Binding-protein-dependent transport system inner membrane component
DONFEKIO_00329 5.9e-177 U Binding-protein-dependent transport system inner membrane component
DONFEKIO_00330 1.2e-241 G Bacterial extracellular solute-binding protein
DONFEKIO_00331 3.4e-194 K helix_turn _helix lactose operon repressor
DONFEKIO_00332 0.0 lacZ 3.2.1.23 G Beta-galactosidase trimerisation domain
DONFEKIO_00333 4.1e-264 S AAA domain
DONFEKIO_00334 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
DONFEKIO_00335 0.0 oppD P Belongs to the ABC transporter superfamily
DONFEKIO_00336 1.2e-172 dppC EP N-terminal TM domain of oligopeptide transport permease C
DONFEKIO_00337 1e-176 appB EP Binding-protein-dependent transport system inner membrane component
DONFEKIO_00338 5.2e-268 pepC 3.4.22.40 E Peptidase C1-like family
DONFEKIO_00339 6.7e-47
DONFEKIO_00340 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DONFEKIO_00341 2.3e-119
DONFEKIO_00342 3.1e-184 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DONFEKIO_00344 3.8e-257 G MFS/sugar transport protein
DONFEKIO_00345 1.1e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DONFEKIO_00346 0.0 lmrA2 V ABC transporter transmembrane region
DONFEKIO_00347 0.0 lmrA1 V ABC transporter, ATP-binding protein
DONFEKIO_00348 1.8e-90 ydgJ K helix_turn_helix multiple antibiotic resistance protein
DONFEKIO_00349 1.6e-277 cycA E Amino acid permease
DONFEKIO_00350 0.0 V FtsX-like permease family
DONFEKIO_00351 9.8e-129 V ABC transporter
DONFEKIO_00352 2e-269 aroP E aromatic amino acid transport protein AroP K03293
DONFEKIO_00353 1.7e-105 S Protein of unknown function, DUF624
DONFEKIO_00354 6.8e-153 rafG G ABC transporter permease
DONFEKIO_00355 4.4e-147 malC G Binding-protein-dependent transport system inner membrane component
DONFEKIO_00356 3.7e-185 K Psort location Cytoplasmic, score
DONFEKIO_00357 7.1e-253 amyE G Bacterial extracellular solute-binding protein
DONFEKIO_00358 3.6e-102 G Phosphoglycerate mutase family
DONFEKIO_00359 4.4e-59 S Protein of unknown function (DUF4235)
DONFEKIO_00360 5e-125 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
DONFEKIO_00361 0.0 pip S YhgE Pip domain protein
DONFEKIO_00362 5.3e-280 pip S YhgE Pip domain protein
DONFEKIO_00363 1.8e-40
DONFEKIO_00367 2.6e-98 L Phage integrase family
DONFEKIO_00370 1.3e-122 S Protein of unknown function DUF45
DONFEKIO_00372 3.6e-257 S Domain of unknown function (DUF4143)
DONFEKIO_00373 3.3e-83 dps P Belongs to the Dps family
DONFEKIO_00374 7.2e-117 L Transposase and inactivated derivatives IS30 family
DONFEKIO_00375 1.1e-88 amyE G Bacterial extracellular solute-binding protein
DONFEKIO_00376 1e-114 S Protein of unknown function, DUF624
DONFEKIO_00377 3.8e-201 K Periplasmic binding protein domain
DONFEKIO_00378 2.1e-292 3.2.1.26 GH32 G Glycosyl hydrolases family 32
DONFEKIO_00379 5.9e-252 amyE G Bacterial extracellular solute-binding protein
DONFEKIO_00380 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
DONFEKIO_00381 3e-187 K Psort location Cytoplasmic, score
DONFEKIO_00382 4.5e-213 L Transposase and inactivated derivatives IS30 family
DONFEKIO_00383 1e-147 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
DONFEKIO_00384 1.2e-51 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
DONFEKIO_00385 7e-75 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
DONFEKIO_00386 5.8e-152 rafG G ABC transporter permease
DONFEKIO_00387 4.2e-150 malC G Binding-protein-dependent transport system inner membrane component
DONFEKIO_00388 1.5e-30 K Psort location Cytoplasmic, score
DONFEKIO_00389 6.9e-72 K Psort location Cytoplasmic, score
DONFEKIO_00390 2e-76 amyE G Bacterial extracellular solute-binding protein
DONFEKIO_00391 4.8e-116 amyE G Bacterial extracellular solute-binding protein
DONFEKIO_00393 5.9e-229 M Protein of unknown function (DUF2961)
DONFEKIO_00394 3e-254 amyE G Bacterial extracellular solute-binding protein
DONFEKIO_00395 8.9e-187 K Periplasmic binding protein-like domain
DONFEKIO_00396 1.5e-266 amyE G Bacterial extracellular solute-binding protein
DONFEKIO_00397 5.6e-83 dps P Belongs to the Dps family
DONFEKIO_00398 2.7e-236 ytfL P Transporter associated domain
DONFEKIO_00399 4.8e-210 S AAA ATPase domain
DONFEKIO_00400 6.6e-122 cah 4.2.1.1 P Reversible hydration of carbon dioxide
DONFEKIO_00401 1e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
DONFEKIO_00402 0.0 trxB2 1.8.1.9 C Thioredoxin domain
DONFEKIO_00403 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
DONFEKIO_00404 4.8e-160
DONFEKIO_00405 1.5e-93 S Uncharacterised protein conserved in bacteria (DUF2194)
DONFEKIO_00406 8.4e-210 S Uncharacterised protein conserved in bacteria (DUF2194)
DONFEKIO_00407 3.6e-279 pelF GT4 M Domain of unknown function (DUF3492)
DONFEKIO_00408 3.8e-282 pelG S Putative exopolysaccharide Exporter (EPS-E)
DONFEKIO_00409 0.0 cotH M CotH kinase protein
DONFEKIO_00410 4.1e-158 P VTC domain
DONFEKIO_00411 8.5e-111 S Domain of unknown function (DUF4956)
DONFEKIO_00412 0.0 yliE T Putative diguanylate phosphodiesterase
DONFEKIO_00413 1.1e-124 S AAA domain
DONFEKIO_00414 2.3e-311 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DONFEKIO_00416 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DONFEKIO_00417 0.0 yjjP S Threonine/Serine exporter, ThrE
DONFEKIO_00418 8e-299 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DONFEKIO_00419 1.3e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DONFEKIO_00420 6.3e-288 S Amidohydrolase family
DONFEKIO_00421 5.5e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DONFEKIO_00422 1.2e-38 S Protein of unknown function (DUF3073)
DONFEKIO_00423 3.6e-112 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DONFEKIO_00424 2.7e-208 2.7.13.3 T Histidine kinase
DONFEKIO_00425 3e-222 EGP Major Facilitator Superfamily
DONFEKIO_00426 3.7e-102 I Sterol carrier protein
DONFEKIO_00427 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DONFEKIO_00428 2.6e-35
DONFEKIO_00429 1.6e-121 gluP 3.4.21.105 S Rhomboid family
DONFEKIO_00431 2.6e-69 crgA D Involved in cell division
DONFEKIO_00432 1.8e-118 S Bacterial protein of unknown function (DUF881)
DONFEKIO_00433 1.5e-230 srtA 3.4.22.70 M Sortase family
DONFEKIO_00434 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
DONFEKIO_00435 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
DONFEKIO_00436 5.7e-172 T Protein tyrosine kinase
DONFEKIO_00437 1.3e-263 pbpA M penicillin-binding protein
DONFEKIO_00438 1.2e-278 rodA D Belongs to the SEDS family
DONFEKIO_00439 3.7e-272 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
DONFEKIO_00440 1.6e-75 fhaB T Inner membrane component of T3SS, cytoplasmic domain
DONFEKIO_00441 2e-129 fhaA T Protein of unknown function (DUF2662)
DONFEKIO_00442 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
DONFEKIO_00443 8.6e-213 pldB 3.1.1.5 I Serine aminopeptidase, S33
DONFEKIO_00444 1.1e-86 hsp20 O Hsp20/alpha crystallin family
DONFEKIO_00445 2.1e-177 yddG EG EamA-like transporter family
DONFEKIO_00446 1.3e-23
DONFEKIO_00447 2.3e-254 S Putative esterase
DONFEKIO_00448 0.0 lysX S Uncharacterised conserved protein (DUF2156)
DONFEKIO_00449 4.8e-201 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DONFEKIO_00450 2e-132 S Pyridoxamine 5'-phosphate oxidase
DONFEKIO_00451 1.4e-198 S Fic/DOC family
DONFEKIO_00452 1.5e-160 M Glycosyltransferase like family 2
DONFEKIO_00453 0.0 KL Domain of unknown function (DUF3427)
DONFEKIO_00454 4.1e-74 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
DONFEKIO_00455 1.7e-51 ybjQ S Putative heavy-metal-binding
DONFEKIO_00456 4.1e-145 yplQ S Haemolysin-III related
DONFEKIO_00458 1e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DONFEKIO_00459 3.3e-214 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
DONFEKIO_00460 0.0 cadA P E1-E2 ATPase
DONFEKIO_00461 3.8e-276 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
DONFEKIO_00462 1.5e-172 htpX O Belongs to the peptidase M48B family
DONFEKIO_00464 3e-173 yicL EG EamA-like transporter family
DONFEKIO_00465 6.1e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
DONFEKIO_00466 1.4e-245 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DONFEKIO_00467 2.2e-282 clcA P Voltage gated chloride channel
DONFEKIO_00468 1.2e-146 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DONFEKIO_00469 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DONFEKIO_00470 3.2e-203 K helix_turn _helix lactose operon repressor
DONFEKIO_00472 2.1e-301 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
DONFEKIO_00473 1.7e-277 scrT G Transporter major facilitator family protein
DONFEKIO_00474 6.9e-179 K helix_turn _helix lactose operon repressor
DONFEKIO_00475 4.7e-252 yhjE EGP Sugar (and other) transporter
DONFEKIO_00476 2.4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DONFEKIO_00477 3.7e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DONFEKIO_00478 1.5e-146 S Psort location Cytoplasmic, score
DONFEKIO_00479 2.2e-190 K Transcriptional regulator
DONFEKIO_00480 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
DONFEKIO_00481 1.2e-186 K Psort location Cytoplasmic, score
DONFEKIO_00482 0.0 M cell wall anchor domain protein
DONFEKIO_00483 0.0 M domain protein
DONFEKIO_00484 1.6e-174 3.4.22.70 M Sortase family
DONFEKIO_00485 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
DONFEKIO_00486 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
DONFEKIO_00487 2.9e-232 malE G Bacterial extracellular solute-binding protein
DONFEKIO_00488 2e-253 malF G Binding-protein-dependent transport system inner membrane component
DONFEKIO_00489 4e-162 malG G Binding-protein-dependent transport system inner membrane component
DONFEKIO_00490 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DONFEKIO_00491 1.1e-175 S HAD-hyrolase-like
DONFEKIO_00492 2.2e-145 traX S TraX protein
DONFEKIO_00493 3.7e-193 K Psort location Cytoplasmic, score
DONFEKIO_00494 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
DONFEKIO_00495 0.0 dnaK O Heat shock 70 kDa protein
DONFEKIO_00496 1e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DONFEKIO_00497 9.4e-157 dnaJ1 O DnaJ molecular chaperone homology domain
DONFEKIO_00498 1.2e-103 hspR K transcriptional regulator, MerR family
DONFEKIO_00499 3.1e-17 F Psort location CytoplasmicMembrane, score 10.00
DONFEKIO_00500 5.1e-115 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
DONFEKIO_00501 5.6e-141 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
DONFEKIO_00502 5.1e-127 S HAD hydrolase, family IA, variant 3
DONFEKIO_00503 2.8e-134 dedA S SNARE associated Golgi protein
DONFEKIO_00504 7.6e-125 cpaE D bacterial-type flagellum organization
DONFEKIO_00505 3.8e-190 cpaF U Type II IV secretion system protein
DONFEKIO_00506 2.8e-97 U Type ii secretion system
DONFEKIO_00507 2.6e-115 gspF NU Type II secretion system (T2SS), protein F
DONFEKIO_00508 1.1e-41 S Protein of unknown function (DUF4244)
DONFEKIO_00509 1.4e-57 U TadE-like protein
DONFEKIO_00510 6.5e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
DONFEKIO_00511 1.2e-216 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
DONFEKIO_00512 6.5e-97 K Bacterial regulatory proteins, tetR family
DONFEKIO_00513 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
DONFEKIO_00514 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DONFEKIO_00515 1.5e-196 3.4.22.70 M Sortase family
DONFEKIO_00516 4.1e-68 V Abi-like protein
DONFEKIO_00517 8e-105 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DONFEKIO_00518 7.6e-73 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DONFEKIO_00519 1.3e-134 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
DONFEKIO_00520 3e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
DONFEKIO_00521 2.6e-213 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DONFEKIO_00522 9.6e-112
DONFEKIO_00523 1.7e-173 L Domain of unknown function (DUF4862)
DONFEKIO_00524 1.4e-168 2.7.1.2 GK ROK family
DONFEKIO_00525 1.3e-125 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DONFEKIO_00526 8.3e-159 3.5.1.106 I carboxylic ester hydrolase activity
DONFEKIO_00527 7.9e-304 E Bacterial extracellular solute-binding proteins, family 5 Middle
DONFEKIO_00528 4.6e-153 oppB6 EP Binding-protein-dependent transport system inner membrane component
DONFEKIO_00529 0.0 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
DONFEKIO_00530 1.7e-148 oppF E ATPases associated with a variety of cellular activities
DONFEKIO_00531 2e-180 nanL 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
DONFEKIO_00532 3.7e-148 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DONFEKIO_00533 4.5e-13 nagA 3.5.1.25 G Amidohydrolase family
DONFEKIO_00534 0.0 nanI 3.2.1.18 GH33 G BNR repeat-like domain
DONFEKIO_00535 2.8e-243 P Domain of unknown function (DUF4143)
DONFEKIO_00536 9e-153 K FCD
DONFEKIO_00537 3.2e-275 S Calcineurin-like phosphoesterase
DONFEKIO_00538 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DONFEKIO_00539 6.8e-96 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DONFEKIO_00540 6.7e-290 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DONFEKIO_00541 4.2e-166 3.6.1.27 I PAP2 superfamily
DONFEKIO_00542 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DONFEKIO_00543 5.9e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DONFEKIO_00544 2.3e-207 holB 2.7.7.7 L DNA polymerase III
DONFEKIO_00545 5.2e-105 K helix_turn _helix lactose operon repressor
DONFEKIO_00546 3.3e-37 ptsH G PTS HPr component phosphorylation site
DONFEKIO_00548 7.8e-294 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DONFEKIO_00549 1.5e-104 S Phosphatidylethanolamine-binding protein
DONFEKIO_00550 2.2e-311 pepD E Peptidase family C69
DONFEKIO_00551 3.4e-288 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
DONFEKIO_00552 6.7e-62 S Macrophage migration inhibitory factor (MIF)
DONFEKIO_00553 8.4e-96 S GtrA-like protein
DONFEKIO_00554 9.7e-248 EGP Major facilitator Superfamily
DONFEKIO_00555 2.6e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
DONFEKIO_00556 2e-158
DONFEKIO_00557 1.4e-161 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
DONFEKIO_00558 1.3e-143 S Protein of unknown function (DUF805)
DONFEKIO_00559 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
DONFEKIO_00560 1.8e-170 V Abi-like protein
DONFEKIO_00561 6.5e-93 3.1.21.3 L PFAM restriction modification system DNA specificity domain
DONFEKIO_00563 3.1e-292 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
DONFEKIO_00564 3e-292 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DONFEKIO_00567 1.3e-109 L Phage integrase, N-terminal SAM-like domain
DONFEKIO_00569 3.7e-295 efeU_1 P Iron permease FTR1 family
DONFEKIO_00570 8e-99 tpd P Fe2+ transport protein
DONFEKIO_00571 7.7e-233 S Predicted membrane protein (DUF2318)
DONFEKIO_00572 7e-221 macB_2 V ABC transporter permease
DONFEKIO_00573 1.6e-199 Z012_06715 V FtsX-like permease family
DONFEKIO_00574 4.5e-146 macB V ABC transporter, ATP-binding protein
DONFEKIO_00575 1.7e-67 S FMN_bind
DONFEKIO_00576 3.2e-101 K Psort location Cytoplasmic, score 8.87
DONFEKIO_00577 8.1e-307 pip S YhgE Pip domain protein
DONFEKIO_00578 0.0 pip S YhgE Pip domain protein
DONFEKIO_00579 2.5e-253 S Putative ABC-transporter type IV
DONFEKIO_00580 1.5e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DONFEKIO_00581 4.8e-138 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
DONFEKIO_00582 3.7e-193 opcA G Glucose-6-phosphate dehydrogenase subunit
DONFEKIO_00583 7.8e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DONFEKIO_00584 3.1e-291 3.5.2.6 V Beta-lactamase enzyme family
DONFEKIO_00586 9.4e-302 pepD E Peptidase family C69
DONFEKIO_00587 1.1e-197 XK27_01805 M Glycosyltransferase like family 2
DONFEKIO_00588 1e-151 icaR K Bacterial regulatory proteins, tetR family
DONFEKIO_00589 2.2e-171 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DONFEKIO_00590 1e-227 amt U Ammonium Transporter Family
DONFEKIO_00591 1e-54 glnB K Nitrogen regulatory protein P-II
DONFEKIO_00592 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
DONFEKIO_00593 4.6e-239 dinF V MatE
DONFEKIO_00594 1.3e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DONFEKIO_00595 8e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
DONFEKIO_00596 1.6e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
DONFEKIO_00597 1.8e-36 S granule-associated protein
DONFEKIO_00598 0.0 ubiB S ABC1 family
DONFEKIO_00600 4.2e-72 K Periplasmic binding protein domain
DONFEKIO_00601 2.6e-63 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
DONFEKIO_00602 2.4e-28 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
DONFEKIO_00603 2.6e-48 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
DONFEKIO_00604 4.5e-155 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DONFEKIO_00605 1.3e-187 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DONFEKIO_00606 4.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
DONFEKIO_00607 4e-76 ssb1 L Single-stranded DNA-binding protein
DONFEKIO_00608 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DONFEKIO_00609 2.7e-71 rplI J Binds to the 23S rRNA
DONFEKIO_00611 6.9e-117 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
DONFEKIO_00612 0.0 pacS 1.9.3.1, 3.6.3.54 P E1-E2 ATPase
DONFEKIO_00613 2.1e-42 csoR S Metal-sensitive transcriptional repressor
DONFEKIO_00614 1.6e-210 rmuC S RmuC family
DONFEKIO_00615 3.1e-110 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DONFEKIO_00616 2.4e-170 spoU 2.1.1.185 J RNA methyltransferase TrmH family
DONFEKIO_00617 4.2e-167 V ABC transporter
DONFEKIO_00618 6.9e-179
DONFEKIO_00619 5.6e-55 K Psort location Cytoplasmic, score
DONFEKIO_00620 2.2e-53 K Psort location Cytoplasmic, score
DONFEKIO_00621 5.9e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DONFEKIO_00622 3.9e-287 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DONFEKIO_00623 7.4e-283 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DONFEKIO_00624 4e-195 2.3.1.57 J Acetyltransferase (GNAT) domain
DONFEKIO_00625 3.3e-52 S Protein of unknown function (DUF2469)
DONFEKIO_00626 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
DONFEKIO_00627 2.7e-293 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DONFEKIO_00629 1.9e-37 pabC 2.6.1.42, 4.1.3.38 EH Amino-transferase class IV
DONFEKIO_00630 2.5e-151 L Transposase
DONFEKIO_00631 5.1e-50 K helix_turn_helix, arabinose operon control protein
DONFEKIO_00632 2.6e-154 araN G Bacterial extracellular solute-binding protein
DONFEKIO_00633 1.6e-120 lacF P Binding-protein-dependent transport system inner membrane component
DONFEKIO_00634 1.3e-114 araQ U Binding-protein-dependent transport system inner membrane component
DONFEKIO_00635 1.1e-131 rafA 3.2.1.22 G alpha-galactosidase
DONFEKIO_00636 6.8e-63 tyrA 5.4.99.5 E Chorismate mutase type II
DONFEKIO_00637 0.0 S domain protein
DONFEKIO_00638 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DONFEKIO_00639 1.2e-280 E Bacterial extracellular solute-binding proteins, family 5 Middle
DONFEKIO_00640 1.3e-125 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DONFEKIO_00641 1.8e-139 KT Transcriptional regulatory protein, C terminal
DONFEKIO_00642 1.9e-116
DONFEKIO_00643 1e-86 mntP P Probably functions as a manganese efflux pump
DONFEKIO_00644 4e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DONFEKIO_00645 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
DONFEKIO_00646 0.0 K RNA polymerase II activating transcription factor binding
DONFEKIO_00648 1.6e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DONFEKIO_00649 6.4e-148 atpB C it plays a direct role in the translocation of protons across the membrane
DONFEKIO_00650 1.7e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DONFEKIO_00651 2.9e-61 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DONFEKIO_00652 2.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DONFEKIO_00653 1.3e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DONFEKIO_00654 5.5e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DONFEKIO_00655 6.1e-282 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DONFEKIO_00656 3.6e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DONFEKIO_00657 1.4e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DONFEKIO_00658 5.5e-159 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
DONFEKIO_00659 2.6e-185
DONFEKIO_00660 3e-179
DONFEKIO_00661 4.5e-172 trxA2 O Tetratricopeptide repeat
DONFEKIO_00662 1.2e-117 cyaA 4.6.1.1 S CYTH
DONFEKIO_00665 3.6e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
DONFEKIO_00666 8.8e-189 plsC2 2.3.1.51 I Phosphate acyltransferases
DONFEKIO_00667 2.7e-180 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
DONFEKIO_00668 2.8e-229 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DONFEKIO_00669 9.9e-219 P Bacterial extracellular solute-binding protein
DONFEKIO_00670 2.9e-160 U Binding-protein-dependent transport system inner membrane component
DONFEKIO_00671 6.9e-151 U Binding-protein-dependent transport system inner membrane component
DONFEKIO_00672 8.2e-238 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DONFEKIO_00673 1.9e-184 S CAAX protease self-immunity
DONFEKIO_00674 1.7e-137 M Mechanosensitive ion channel
DONFEKIO_00675 2.5e-272 aspA 4.3.1.1 E Fumarase C C-terminus
DONFEKIO_00676 9.3e-11 L Transposase DDE domain
DONFEKIO_00677 9e-167 4.2.1.68 M Enolase C-terminal domain-like
DONFEKIO_00678 4.5e-146 IQ KR domain
DONFEKIO_00679 1.6e-154 S Amidohydrolase
DONFEKIO_00680 2.8e-165 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
DONFEKIO_00681 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
DONFEKIO_00682 2.2e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
DONFEKIO_00683 3.1e-53 acyP 3.6.1.7 C Acylphosphatase
DONFEKIO_00684 5.1e-254 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DONFEKIO_00685 1.8e-220 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DONFEKIO_00686 4.6e-111 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
DONFEKIO_00687 5e-99
DONFEKIO_00688 9.1e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DONFEKIO_00689 1.3e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
DONFEKIO_00690 8.1e-279 S Uncharacterized protein conserved in bacteria (DUF2252)
DONFEKIO_00691 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
DONFEKIO_00692 1.1e-217 EGP Major facilitator Superfamily
DONFEKIO_00693 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
DONFEKIO_00694 3.4e-123 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
DONFEKIO_00695 7e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DONFEKIO_00696 1.7e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
DONFEKIO_00697 2.6e-161 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DONFEKIO_00698 6.9e-130 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DONFEKIO_00699 3e-47 M Lysin motif
DONFEKIO_00700 8.4e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DONFEKIO_00701 7.5e-230 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DONFEKIO_00702 0.0 L DNA helicase
DONFEKIO_00703 1.3e-93 mraZ K Belongs to the MraZ family
DONFEKIO_00704 5.7e-189 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DONFEKIO_00705 4e-67 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DONFEKIO_00706 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
DONFEKIO_00707 2e-155 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DONFEKIO_00708 3e-241 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DONFEKIO_00709 1.2e-205 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DONFEKIO_00710 1.1e-272 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DONFEKIO_00711 9.7e-225 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
DONFEKIO_00712 5.9e-219 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DONFEKIO_00713 6.2e-285 murC 6.3.2.8 M Belongs to the MurCDEF family
DONFEKIO_00714 7.3e-173 ftsQ 6.3.2.4 D Cell division protein FtsQ
DONFEKIO_00715 7e-15
DONFEKIO_00716 2.2e-87 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DONFEKIO_00717 1.8e-99 G Major Facilitator Superfamily
DONFEKIO_00718 1.2e-168 2.7.1.4 G pfkB family carbohydrate kinase
DONFEKIO_00719 6.1e-227 GK ROK family
DONFEKIO_00720 2.2e-165 2.7.1.2 GK ROK family
DONFEKIO_00721 9e-209 GK ROK family
DONFEKIO_00722 6.2e-151 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DONFEKIO_00723 1.9e-247 nagA 3.5.1.25 G Amidohydrolase family
DONFEKIO_00724 6.6e-98 3.6.1.55 F NUDIX domain
DONFEKIO_00725 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
DONFEKIO_00726 2.3e-303 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
DONFEKIO_00727 0.0 smc D Required for chromosome condensation and partitioning
DONFEKIO_00728 2.3e-48 V Acetyltransferase (GNAT) domain
DONFEKIO_00729 1.3e-20 V Acetyltransferase (GNAT) domain
DONFEKIO_00730 1.6e-193 V Acetyltransferase (GNAT) domain
DONFEKIO_00731 6.6e-287 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DONFEKIO_00732 1.8e-136 sigH K Belongs to the sigma-70 factor family. ECF subfamily
DONFEKIO_00733 3.3e-52
DONFEKIO_00734 1.1e-188 galM 5.1.3.3 G Aldose 1-epimerase
DONFEKIO_00735 8.5e-192 galM 5.1.3.3 G Aldose 1-epimerase
DONFEKIO_00736 3.7e-182 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DONFEKIO_00737 4.2e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DONFEKIO_00738 1.3e-196 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DONFEKIO_00739 7.2e-135 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
DONFEKIO_00740 1.7e-113 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DONFEKIO_00741 6.2e-25 rpmI J Ribosomal protein L35
DONFEKIO_00742 1.3e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DONFEKIO_00743 3.8e-194 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DONFEKIO_00744 1.9e-159 xerD D recombinase XerD
DONFEKIO_00745 3.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
DONFEKIO_00746 8.5e-151 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DONFEKIO_00747 6.6e-114 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DONFEKIO_00748 3.4e-160 nrtR 3.6.1.55 F NUDIX hydrolase
DONFEKIO_00749 3.1e-250 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DONFEKIO_00750 3.3e-297 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
DONFEKIO_00751 5.5e-161 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
DONFEKIO_00752 1.8e-237 iscS1 2.8.1.7 E Aminotransferase class-V
DONFEKIO_00753 4.5e-19 naiP U Sugar (and other) transporter
DONFEKIO_00754 0.0 V FtsX-like permease family
DONFEKIO_00755 4.8e-137 V ATPases associated with a variety of cellular activities
DONFEKIO_00756 7e-107 K Virulence activator alpha C-term
DONFEKIO_00757 0.0 typA T Elongation factor G C-terminus
DONFEKIO_00758 1.1e-78
DONFEKIO_00759 4.5e-188 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
DONFEKIO_00760 7.2e-189 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
DONFEKIO_00761 2.9e-41
DONFEKIO_00762 0.0 MV MacB-like periplasmic core domain
DONFEKIO_00763 2.2e-148 V ABC transporter, ATP-binding protein
DONFEKIO_00764 3.6e-188 xerC D Belongs to the 'phage' integrase family. XerC subfamily
DONFEKIO_00765 0.0 E ABC transporter, substrate-binding protein, family 5
DONFEKIO_00766 8.9e-154 dppB EP Binding-protein-dependent transport system inner membrane component
DONFEKIO_00767 1.1e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
DONFEKIO_00768 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
DONFEKIO_00769 3.3e-171 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
DONFEKIO_00770 7.3e-155 S Protein of unknown function (DUF3710)
DONFEKIO_00771 3.8e-134 S Protein of unknown function (DUF3159)
DONFEKIO_00772 1.5e-241 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DONFEKIO_00773 8.2e-97
DONFEKIO_00774 0.0 ctpE P E1-E2 ATPase
DONFEKIO_00775 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DONFEKIO_00776 6.8e-121 E Psort location Cytoplasmic, score 8.87
DONFEKIO_00777 2.2e-82 K helix_turn_helix, Lux Regulon
DONFEKIO_00778 2.8e-135 ybhL S Belongs to the BI1 family
DONFEKIO_00779 3.6e-166 ydeD EG EamA-like transporter family
DONFEKIO_00780 5.2e-150 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
DONFEKIO_00781 2e-277 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DONFEKIO_00782 1.1e-181 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DONFEKIO_00783 1.7e-149 fic D Fic/DOC family
DONFEKIO_00784 0.0 ftsK D FtsK SpoIIIE family protein
DONFEKIO_00785 1.2e-117 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DONFEKIO_00786 4.6e-97 cinA 3.5.1.42 S Belongs to the CinA family
DONFEKIO_00787 1.2e-78 K Helix-turn-helix XRE-family like proteins
DONFEKIO_00788 7e-39 S Protein of unknown function (DUF3046)
DONFEKIO_00789 1.1e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DONFEKIO_00790 1.5e-101 recX S Modulates RecA activity
DONFEKIO_00791 2.4e-113 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DONFEKIO_00792 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DONFEKIO_00793 6e-191 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DONFEKIO_00794 5.9e-118
DONFEKIO_00795 6.2e-131 plsC2 2.3.1.51 I Phosphate acyltransferases
DONFEKIO_00796 0.0 pknL 2.7.11.1 KLT PASTA
DONFEKIO_00797 2.9e-196 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
DONFEKIO_00798 8.1e-114
DONFEKIO_00799 8.2e-191 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DONFEKIO_00800 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DONFEKIO_00801 1e-221 G Major Facilitator Superfamily
DONFEKIO_00802 1.1e-170 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DONFEKIO_00803 0.0 lhr L DEAD DEAH box helicase
DONFEKIO_00804 1.2e-48 K Psort location Cytoplasmic, score
DONFEKIO_00805 1.8e-43 K Psort location Cytoplasmic, score
DONFEKIO_00806 4.6e-43 K AraC-like ligand binding domain
DONFEKIO_00807 3e-110 G Bacterial extracellular solute-binding protein
DONFEKIO_00808 1.2e-08 E GDSL-like Lipase/Acylhydrolase
DONFEKIO_00809 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DONFEKIO_00810 5e-232 S Type I phosphodiesterase / nucleotide pyrophosphatase
DONFEKIO_00811 2.2e-148 S Protein of unknown function (DUF3071)
DONFEKIO_00812 1.4e-47 S Domain of unknown function (DUF4193)
DONFEKIO_00813 2.9e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DONFEKIO_00814 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DONFEKIO_00815 6e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DONFEKIO_00816 2.3e-74
DONFEKIO_00818 7.2e-250 S HipA-like C-terminal domain
DONFEKIO_00819 1e-171 S Fic/DOC family
DONFEKIO_00820 7e-39
DONFEKIO_00821 1.2e-17 L Phage integrase family
DONFEKIO_00823 6.7e-143 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
DONFEKIO_00824 5.3e-136 S UPF0126 domain
DONFEKIO_00825 5.8e-34 rpsT J Binds directly to 16S ribosomal RNA
DONFEKIO_00826 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DONFEKIO_00827 7.4e-255 hemN H Involved in the biosynthesis of porphyrin-containing compound
DONFEKIO_00829 1e-190 K helix_turn _helix lactose operon repressor
DONFEKIO_00830 1.4e-64 K helix_turn _helix lactose operon repressor
DONFEKIO_00831 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
DONFEKIO_00832 1.4e-305 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DONFEKIO_00833 5.4e-44
DONFEKIO_00834 0.0 E ABC transporter, substrate-binding protein, family 5
DONFEKIO_00835 0.0 S Glycosyl hydrolases related to GH101 family, GH129
DONFEKIO_00836 6.6e-81
DONFEKIO_00837 1.3e-243 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
DONFEKIO_00838 8.4e-159 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
DONFEKIO_00839 5.8e-160 S Sucrose-6F-phosphate phosphohydrolase
DONFEKIO_00841 4.3e-81 G transmembrane transporter activity
DONFEKIO_00843 1.9e-204 EGP Major facilitator Superfamily
DONFEKIO_00844 5.9e-127 L Transposase, Mutator family
DONFEKIO_00845 2.3e-93 bcp 1.11.1.15 O Redoxin
DONFEKIO_00846 4.1e-142
DONFEKIO_00847 2.6e-42 L Transposase, Mutator family
DONFEKIO_00848 1.5e-177 I alpha/beta hydrolase fold
DONFEKIO_00849 2.5e-89 S Appr-1'-p processing enzyme
DONFEKIO_00850 7.2e-146 S phosphoesterase or phosphohydrolase
DONFEKIO_00851 2e-140 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DONFEKIO_00853 1.6e-131 S Phospholipase/Carboxylesterase
DONFEKIO_00854 2.7e-202 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DONFEKIO_00855 1.3e-99 sixA 3.6.1.55 T Phosphoglycerate mutase family
DONFEKIO_00857 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DONFEKIO_00858 2.8e-162 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
DONFEKIO_00859 1.7e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DONFEKIO_00860 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
DONFEKIO_00861 8.3e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DONFEKIO_00862 7e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
DONFEKIO_00863 3.3e-291 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DONFEKIO_00864 7.7e-177 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
DONFEKIO_00865 6.3e-159 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
DONFEKIO_00866 3.3e-183 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DONFEKIO_00867 5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DONFEKIO_00868 3.5e-28
DONFEKIO_00869 2.8e-218 MA20_36090 S Psort location Cytoplasmic, score 8.87
DONFEKIO_00870 9.4e-172 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
DONFEKIO_00871 9.4e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DONFEKIO_00872 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DONFEKIO_00873 3.7e-301 ybiT S ABC transporter
DONFEKIO_00874 5.2e-130 S Enoyl-(Acyl carrier protein) reductase
DONFEKIO_00875 5.2e-56 P ABC transporter
DONFEKIO_00876 8.3e-59 P ABC transporter
DONFEKIO_00877 3.6e-50 XK26_04485 P Cobalt transport protein
DONFEKIO_00878 3.4e-33 XK26_04485 P Cobalt transport protein
DONFEKIO_00879 5e-234 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
DONFEKIO_00880 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DONFEKIO_00881 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DONFEKIO_00882 5.6e-191 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
DONFEKIO_00883 2.6e-180 rapZ S Displays ATPase and GTPase activities
DONFEKIO_00884 3.5e-169 whiA K May be required for sporulation
DONFEKIO_00885 7.9e-219 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
DONFEKIO_00886 3.5e-146 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DONFEKIO_00887 2.5e-34 secG U Preprotein translocase SecG subunit
DONFEKIO_00888 1.9e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DONFEKIO_00889 2.9e-159 S Sucrose-6F-phosphate phosphohydrolase
DONFEKIO_00890 3.6e-301 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
DONFEKIO_00891 2.9e-189
DONFEKIO_00892 1.4e-240 brnQ U Component of the transport system for branched-chain amino acids
DONFEKIO_00893 3.6e-202 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DONFEKIO_00894 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
DONFEKIO_00895 3.7e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DONFEKIO_00896 2e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DONFEKIO_00897 9.6e-157 G Fructosamine kinase
DONFEKIO_00898 4.1e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DONFEKIO_00899 1.2e-133 S PAC2 family
DONFEKIO_00905 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DONFEKIO_00906 7.7e-111 hit 2.7.7.53 FG HIT domain
DONFEKIO_00907 2e-111 yebC K transcriptional regulatory protein
DONFEKIO_00908 2.7e-100 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DONFEKIO_00909 3.2e-107 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DONFEKIO_00910 9.4e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DONFEKIO_00911 1.2e-52 yajC U Preprotein translocase subunit
DONFEKIO_00912 2.7e-100 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DONFEKIO_00913 6.9e-223 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DONFEKIO_00914 1.4e-164 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DONFEKIO_00915 1.2e-228
DONFEKIO_00916 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DONFEKIO_00917 4.8e-32
DONFEKIO_00918 2.9e-120 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DONFEKIO_00919 4.5e-143 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DONFEKIO_00920 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
DONFEKIO_00922 2.5e-163 supH S Sucrose-6F-phosphate phosphohydrolase
DONFEKIO_00923 9.3e-294 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
DONFEKIO_00924 0.0 pafB K WYL domain
DONFEKIO_00925 6.8e-53
DONFEKIO_00926 0.0 helY L DEAD DEAH box helicase
DONFEKIO_00927 5.1e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
DONFEKIO_00928 5.7e-140 pgp 3.1.3.18 S HAD-hyrolase-like
DONFEKIO_00929 6.9e-36
DONFEKIO_00930 4.9e-64
DONFEKIO_00931 2.6e-112 K helix_turn_helix, mercury resistance
DONFEKIO_00932 6.7e-75 garA T Inner membrane component of T3SS, cytoplasmic domain
DONFEKIO_00933 5.9e-141 S Bacterial protein of unknown function (DUF881)
DONFEKIO_00934 3.9e-35 sbp S Protein of unknown function (DUF1290)
DONFEKIO_00935 1e-168 S Bacterial protein of unknown function (DUF881)
DONFEKIO_00936 3.9e-105 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DONFEKIO_00937 8.7e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
DONFEKIO_00938 9.9e-42 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
DONFEKIO_00939 9.4e-113 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
DONFEKIO_00940 3.1e-186 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DONFEKIO_00941 2.1e-160 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DONFEKIO_00942 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DONFEKIO_00943 1.6e-131 S SOS response associated peptidase (SRAP)
DONFEKIO_00944 1.4e-156 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DONFEKIO_00945 1.1e-259 mmuP E amino acid
DONFEKIO_00946 1.9e-50 EGP Major facilitator Superfamily
DONFEKIO_00947 9.3e-189 V VanZ like family
DONFEKIO_00948 6e-69 cefD 5.1.1.17 E Aminotransferase, class V
DONFEKIO_00949 3.3e-100 S Acetyltransferase (GNAT) domain
DONFEKIO_00950 1.5e-50
DONFEKIO_00951 5.2e-121
DONFEKIO_00954 2e-35 2.7.13.3 T Histidine kinase
DONFEKIO_00955 1.1e-193 2.7.13.3 T Histidine kinase
DONFEKIO_00956 5.3e-127 K helix_turn_helix, Lux Regulon
DONFEKIO_00957 3e-95
DONFEKIO_00958 2.8e-144 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DONFEKIO_00959 1.4e-124 lolD Q ATPases associated with a variety of cellular activities
DONFEKIO_00960 1.5e-177 V MacB-like periplasmic core domain
DONFEKIO_00961 3.2e-40 relB L RelB antitoxin
DONFEKIO_00962 3.8e-50 S Bacterial toxin of type II toxin-antitoxin system, YafQ
DONFEKIO_00963 8.4e-26 2.7.13.3 T Histidine kinase
DONFEKIO_00964 7.8e-97 rpoE4 K Sigma-70 region 2
DONFEKIO_00965 7.5e-19 S Psort location CytoplasmicMembrane, score
DONFEKIO_00966 2.1e-106
DONFEKIO_00967 8.3e-137
DONFEKIO_00968 4.4e-163 yfiL V ATPases associated with a variety of cellular activities
DONFEKIO_00969 2e-70
DONFEKIO_00970 9.1e-62
DONFEKIO_00971 5.3e-148 S EamA-like transporter family
DONFEKIO_00972 1.4e-102
DONFEKIO_00973 2.5e-127
DONFEKIO_00974 4.3e-97 V ATPases associated with a variety of cellular activities
DONFEKIO_00975 2.3e-64 L Transposase and inactivated derivatives IS30 family
DONFEKIO_00976 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DONFEKIO_00977 1e-77 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
DONFEKIO_00978 2.9e-176 L Phage integrase family
DONFEKIO_00979 4.6e-157 2.7.7.7 L Domain of unknown function (DUF4357)
DONFEKIO_00980 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
DONFEKIO_00981 2.4e-149 3.1.21.3 V type I restriction modification DNA specificity domain
DONFEKIO_00982 5.3e-268 K Putative DNA-binding domain
DONFEKIO_00983 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
DONFEKIO_00984 9.7e-150 G Fic/DOC family
DONFEKIO_00985 1.3e-229 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DONFEKIO_00986 4.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DONFEKIO_00987 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
DONFEKIO_00988 9.3e-189 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DONFEKIO_00989 4.3e-132 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DONFEKIO_00990 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DONFEKIO_00991 2.1e-118 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
DONFEKIO_00992 2.2e-117 apl 3.1.3.1 S SNARE associated Golgi protein
DONFEKIO_00993 2.3e-287 arc O AAA ATPase forming ring-shaped complexes
DONFEKIO_00994 9.6e-103 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DONFEKIO_00995 6.6e-130 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
DONFEKIO_00996 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
DONFEKIO_00997 8.9e-175 hisN 3.1.3.25 G Inositol monophosphatase family
DONFEKIO_00999 5.4e-286 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DONFEKIO_01000 8.1e-42 hup L Belongs to the bacterial histone-like protein family
DONFEKIO_01001 0.0 S Lysylphosphatidylglycerol synthase TM region
DONFEKIO_01002 3.3e-280 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
DONFEKIO_01003 1.3e-111 ykoE S ABC-type cobalt transport system, permease component
DONFEKIO_01004 2.2e-253 S PGAP1-like protein
DONFEKIO_01005 3.1e-56
DONFEKIO_01006 8.4e-153 S von Willebrand factor (vWF) type A domain
DONFEKIO_01007 3.3e-189 S von Willebrand factor (vWF) type A domain
DONFEKIO_01008 3.9e-85
DONFEKIO_01009 1.3e-163 S Protein of unknown function DUF58
DONFEKIO_01010 4.2e-187 moxR S ATPase family associated with various cellular activities (AAA)
DONFEKIO_01011 3.8e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DONFEKIO_01012 6.9e-84 S LytR cell envelope-related transcriptional attenuator
DONFEKIO_01013 6.1e-38 K 'Cold-shock' DNA-binding domain
DONFEKIO_01014 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DONFEKIO_01015 4.2e-33 S Proteins of 100 residues with WXG
DONFEKIO_01016 4.3e-99
DONFEKIO_01017 2e-132 KT Response regulator receiver domain protein
DONFEKIO_01018 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DONFEKIO_01019 1.7e-66 cspB K 'Cold-shock' DNA-binding domain
DONFEKIO_01020 1.4e-176 S Protein of unknown function (DUF3027)
DONFEKIO_01021 2.4e-178 uspA T Belongs to the universal stress protein A family
DONFEKIO_01022 0.0 clpC O ATPase family associated with various cellular activities (AAA)
DONFEKIO_01023 3e-26 K helix_turn_helix, arabinose operon control protein
DONFEKIO_01024 3e-132 xylE U Sugar (and other) transporter
DONFEKIO_01025 9.6e-59 lipA I Hydrolase, alpha beta domain protein
DONFEKIO_01026 0.0 3.1.3.5 F 5'-nucleotidase, C-terminal domain
DONFEKIO_01027 8.2e-223 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
DONFEKIO_01028 1.3e-260 hisS 6.1.1.21 J Histidyl-tRNA synthetase
DONFEKIO_01029 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DONFEKIO_01030 6.1e-102 S Aminoacyl-tRNA editing domain
DONFEKIO_01031 3.1e-153 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
DONFEKIO_01032 5.9e-146 gluB ET Belongs to the bacterial solute-binding protein 3 family
DONFEKIO_01033 4.4e-110 gluC E Binding-protein-dependent transport system inner membrane component
DONFEKIO_01034 1.2e-194 gluD E Binding-protein-dependent transport system inner membrane component
DONFEKIO_01035 3.4e-291 phoN I PAP2 superfamily
DONFEKIO_01036 8.7e-111 argO S LysE type translocator
DONFEKIO_01037 6.3e-287 ydfD EK Alanine-glyoxylate amino-transferase
DONFEKIO_01039 4e-198 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
DONFEKIO_01040 0.0 helY L DEAD DEAH box helicase
DONFEKIO_01041 1.8e-251 rarA L Recombination factor protein RarA
DONFEKIO_01042 6.9e-11 KT Transcriptional regulatory protein, C terminal
DONFEKIO_01043 2.3e-33 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DONFEKIO_01044 4.2e-251 EGP Major facilitator Superfamily
DONFEKIO_01045 3.8e-187 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DONFEKIO_01046 6.9e-52
DONFEKIO_01047 1.6e-53 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
DONFEKIO_01048 3.1e-47 yhbY J CRS1_YhbY
DONFEKIO_01049 0.0 ecfA GP ABC transporter, ATP-binding protein
DONFEKIO_01050 1.3e-93 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DONFEKIO_01051 6.4e-198 S Glycosyltransferase, group 2 family protein
DONFEKIO_01052 2.5e-149 C Putative TM nitroreductase
DONFEKIO_01053 3.2e-141 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
DONFEKIO_01054 3e-303 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
DONFEKIO_01055 6.2e-241 lacY P LacY proton/sugar symporter
DONFEKIO_01056 1.8e-195 K helix_turn _helix lactose operon repressor
DONFEKIO_01057 3.5e-258 O SERine Proteinase INhibitors
DONFEKIO_01058 7.2e-189
DONFEKIO_01059 6.1e-123 K helix_turn_helix, Lux Regulon
DONFEKIO_01060 2.5e-216 2.7.13.3 T Histidine kinase
DONFEKIO_01061 2.7e-247 ydjK G Sugar (and other) transporter
DONFEKIO_01062 5.6e-62 S Thiamine-binding protein
DONFEKIO_01063 8.7e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DONFEKIO_01064 7.6e-230 O AAA domain (Cdc48 subfamily)
DONFEKIO_01065 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DONFEKIO_01066 4.1e-154 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DONFEKIO_01067 6.7e-297 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
DONFEKIO_01068 5.7e-249 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DONFEKIO_01069 1.2e-211 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DONFEKIO_01070 5.9e-69 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DONFEKIO_01071 4.9e-45 yggT S YGGT family
DONFEKIO_01072 5.3e-22 tccB2 V DivIVA protein
DONFEKIO_01073 5.4e-90 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DONFEKIO_01074 9e-178 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DONFEKIO_01075 1.7e-201 K WYL domain
DONFEKIO_01076 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
DONFEKIO_01077 3e-34 yneG S Domain of unknown function (DUF4186)
DONFEKIO_01078 7.9e-168 dkgA 1.1.1.346 C Aldo/keto reductase family
DONFEKIO_01079 0.0 4.2.1.53 S MCRA family
DONFEKIO_01080 9.1e-253 3.2.1.14 GH18 S Carbohydrate binding domain
DONFEKIO_01081 0.0 M probably involved in cell wall
DONFEKIO_01083 7.4e-48 4.1.1.44 L Cupin 2, conserved barrel domain protein
DONFEKIO_01084 2.3e-185 S Membrane transport protein
DONFEKIO_01085 1.4e-40 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
DONFEKIO_01086 5.7e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
DONFEKIO_01088 3.2e-124 magIII L endonuclease III
DONFEKIO_01089 1.1e-242 vbsD V MatE
DONFEKIO_01090 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DONFEKIO_01091 3.8e-101 K LysR substrate binding domain
DONFEKIO_01092 4.7e-143 K LysR substrate binding domain
DONFEKIO_01093 1.3e-190 K helix_turn _helix lactose operon repressor
DONFEKIO_01094 4.5e-161 P Phosphate transporter family
DONFEKIO_01095 2.3e-163 ugpA P Binding-protein-dependent transport system inner membrane component
DONFEKIO_01096 4e-142 ugpE G Binding-protein-dependent transport system inner membrane component
DONFEKIO_01097 2.6e-239 ugpB G Bacterial extracellular solute-binding protein
DONFEKIO_01098 6.4e-170 ugpQ 3.1.4.46 C Domain of unknown function
DONFEKIO_01099 3.4e-109 P Protein of unknown function DUF47
DONFEKIO_01100 1.4e-259 S Domain of unknown function (DUF4143)
DONFEKIO_01101 1.9e-197 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
DONFEKIO_01102 6.4e-76 K MerR family regulatory protein
DONFEKIO_01103 5.8e-89 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DONFEKIO_01104 1.2e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DONFEKIO_01105 2.7e-32 S Psort location CytoplasmicMembrane, score
DONFEKIO_01106 7.3e-184 MA20_14895 S Conserved hypothetical protein 698
DONFEKIO_01107 7.1e-147 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
DONFEKIO_01108 3e-128 tmp1 S Domain of unknown function (DUF4391)
DONFEKIO_01109 6.2e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DONFEKIO_01110 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DONFEKIO_01111 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DONFEKIO_01112 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DONFEKIO_01113 6.6e-111 yocS S SBF-like CPA transporter family (DUF4137)
DONFEKIO_01115 4.2e-197 ltaE 4.1.2.48 E Beta-eliminating lyase
DONFEKIO_01116 8.1e-221 M Glycosyl transferase 4-like domain
DONFEKIO_01117 1.6e-227 mtnE 2.6.1.83 E Aminotransferase class I and II
DONFEKIO_01118 7.4e-223 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DONFEKIO_01119 9.5e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DONFEKIO_01120 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
DONFEKIO_01121 6.3e-222 I alpha/beta hydrolase fold
DONFEKIO_01122 3e-251 Q D-alanine [D-alanyl carrier protein] ligase activity
DONFEKIO_01123 1.3e-109 Q D-alanine [D-alanyl carrier protein] ligase activity
DONFEKIO_01124 4.7e-102 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
DONFEKIO_01125 1.5e-13 C Aldo/keto reductase family
DONFEKIO_01126 2.3e-31
DONFEKIO_01127 5.5e-300 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
DONFEKIO_01128 2.7e-293 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DONFEKIO_01129 9.2e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DONFEKIO_01130 1.1e-242 purD 6.3.4.13 F Belongs to the GARS family
DONFEKIO_01131 1.9e-297 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
DONFEKIO_01132 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DONFEKIO_01133 7.3e-156 P Zinc-uptake complex component A periplasmic
DONFEKIO_01134 1.5e-98 S cobalamin synthesis protein
DONFEKIO_01135 3.9e-29 rpmB J Ribosomal L28 family
DONFEKIO_01136 1.4e-20 rpmG J Ribosomal protein L33
DONFEKIO_01137 2.5e-44 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DONFEKIO_01138 4.4e-34 rpmE2 J Ribosomal protein L31
DONFEKIO_01139 1.1e-14 rpmJ J Ribosomal protein L36
DONFEKIO_01140 1.3e-18 J Ribosomal L32p protein family
DONFEKIO_01141 2.3e-25 adcA P ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
DONFEKIO_01142 4.1e-169 ycgR S Predicted permease
DONFEKIO_01143 7.8e-140 S TIGRFAM TIGR03943 family protein
DONFEKIO_01144 2.4e-84 zur P Ferric uptake regulator family
DONFEKIO_01145 7.1e-64
DONFEKIO_01146 1.1e-70 XK27_06785 V ABC transporter
DONFEKIO_01147 1.2e-27 ylbB V FtsX-like permease family
DONFEKIO_01148 6.6e-79 ylbB V FtsX-like permease family
DONFEKIO_01149 1.2e-68 zur P Belongs to the Fur family
DONFEKIO_01150 1.1e-222 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DONFEKIO_01151 1.4e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DONFEKIO_01152 2.4e-181 adh3 C Zinc-binding dehydrogenase
DONFEKIO_01153 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DONFEKIO_01154 1.5e-275 macB_8 V MacB-like periplasmic core domain
DONFEKIO_01155 1e-184 M Conserved repeat domain
DONFEKIO_01156 1.7e-129 V ATPases associated with a variety of cellular activities
DONFEKIO_01157 8.5e-87 msrA 1.8.4.11, 1.8.4.12 O peptide-methionine (S)-S-oxide reductase activity
DONFEKIO_01158 0.0 E ABC transporter, substrate-binding protein, family 5
DONFEKIO_01159 3.6e-15 L Psort location Cytoplasmic, score 8.87
DONFEKIO_01160 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DONFEKIO_01161 9.9e-225 K helix_turn _helix lactose operon repressor
DONFEKIO_01162 4.3e-258 G Bacterial extracellular solute-binding protein
DONFEKIO_01165 5.1e-159 K Helix-turn-helix domain, rpiR family
DONFEKIO_01166 7e-43 G Alpha-L-arabinofuranosidase C-terminal domain
DONFEKIO_01167 3.3e-30
DONFEKIO_01168 8.5e-210 ybiR P Citrate transporter
DONFEKIO_01169 1.7e-295 EK Alanine-glyoxylate amino-transferase
DONFEKIO_01170 9.6e-115 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DONFEKIO_01171 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DONFEKIO_01172 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DONFEKIO_01173 6.8e-245 dgt 3.1.5.1 F Phosphohydrolase-associated domain
DONFEKIO_01174 4.1e-264 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DONFEKIO_01175 4.3e-272 yhdG E aromatic amino acid transport protein AroP K03293
DONFEKIO_01176 6.5e-104 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DONFEKIO_01177 8e-93 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DONFEKIO_01178 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DONFEKIO_01179 4.5e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DONFEKIO_01180 9.7e-194 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
DONFEKIO_01181 1.3e-137 sapF E ATPases associated with a variety of cellular activities
DONFEKIO_01182 6.5e-137 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
DONFEKIO_01183 2.4e-149 EP Binding-protein-dependent transport system inner membrane component
DONFEKIO_01184 2.5e-167 P Binding-protein-dependent transport system inner membrane component
DONFEKIO_01185 3.4e-289 E ABC transporter, substrate-binding protein, family 5
DONFEKIO_01186 6.9e-144 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DONFEKIO_01187 4e-278 G Bacterial extracellular solute-binding protein
DONFEKIO_01188 1.7e-259 G Bacterial extracellular solute-binding protein
DONFEKIO_01189 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DONFEKIO_01190 1.4e-123 insK L Integrase core domain
DONFEKIO_01191 1.9e-66 L Helix-turn-helix domain
DONFEKIO_01192 3.5e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DONFEKIO_01193 6.5e-66 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DONFEKIO_01194 2.7e-134 3.1.3.85 G Phosphoglycerate mutase family
DONFEKIO_01197 1.4e-156 S Sucrose-6F-phosphate phosphohydrolase
DONFEKIO_01198 2.7e-177 metQ P NLPA lipoprotein
DONFEKIO_01199 3.2e-220 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DONFEKIO_01200 7.4e-113 metI P Binding-protein-dependent transport system inner membrane component
DONFEKIO_01201 4.1e-225 S Peptidase dimerisation domain
DONFEKIO_01202 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DONFEKIO_01203 2.6e-38
DONFEKIO_01204 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
DONFEKIO_01205 8.7e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DONFEKIO_01206 9.8e-120 S Protein of unknown function (DUF3000)
DONFEKIO_01207 7.6e-252 rnd 3.1.13.5 J 3'-5' exonuclease
DONFEKIO_01208 4.4e-234 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DONFEKIO_01209 3.3e-245 clcA_2 P Voltage gated chloride channel
DONFEKIO_01210 2e-59
DONFEKIO_01211 6.5e-116 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DONFEKIO_01212 7.3e-121 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DONFEKIO_01213 2.1e-252 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DONFEKIO_01216 3.3e-241 patB 4.4.1.8 E Aminotransferase, class I II
DONFEKIO_01217 1.3e-238 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DONFEKIO_01218 3.6e-168 fmt2 3.2.2.10 S Belongs to the LOG family
DONFEKIO_01219 1.9e-113 safC S O-methyltransferase
DONFEKIO_01220 4.2e-183 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
DONFEKIO_01221 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
DONFEKIO_01222 0.0 dprA 5.99.1.2 LU DNA recombination-mediator protein A
DONFEKIO_01223 4.4e-291 comM O Magnesium chelatase, subunit ChlI C-terminal
DONFEKIO_01224 2.2e-75 yraN L Belongs to the UPF0102 family
DONFEKIO_01225 1.6e-23 L Transposase and inactivated derivatives IS30 family
DONFEKIO_01226 2.8e-165 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DONFEKIO_01227 2.5e-250 metY 2.5.1.49 E Aminotransferase class-V
DONFEKIO_01228 7.8e-166 V ABC transporter, ATP-binding protein
DONFEKIO_01229 0.0 MV MacB-like periplasmic core domain
DONFEKIO_01230 4.7e-132 K helix_turn_helix, Lux Regulon
DONFEKIO_01231 0.0 tcsS2 T Histidine kinase
DONFEKIO_01232 4.1e-294 pip 3.4.11.5 S alpha/beta hydrolase fold
DONFEKIO_01233 3.5e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DONFEKIO_01234 9.6e-155 cjaA ET Bacterial periplasmic substrate-binding proteins
DONFEKIO_01235 1.2e-138 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
DONFEKIO_01236 3.5e-118 E Binding-protein-dependent transport system inner membrane component
DONFEKIO_01237 6.7e-111 papP E Binding-protein-dependent transport system inner membrane component
DONFEKIO_01238 1.7e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DONFEKIO_01239 1.4e-164 K Arac family
DONFEKIO_01240 1.2e-28 S rRNA binding
DONFEKIO_01242 1.6e-44 V MatE
DONFEKIO_01243 1.3e-171 V MatE
DONFEKIO_01244 0.0 drrC L ABC transporter
DONFEKIO_01245 1.6e-14 2.7.7.7 L Transposase, Mutator family
DONFEKIO_01246 9.1e-234 XK27_00240 K Fic/DOC family
DONFEKIO_01247 1.1e-60 yccF S Inner membrane component domain
DONFEKIO_01248 1.3e-159 ksgA 2.1.1.182 J Methyltransferase domain
DONFEKIO_01249 2.5e-67 S Cupin 2, conserved barrel domain protein
DONFEKIO_01250 1.5e-52 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
DONFEKIO_01251 1.1e-37 L RelB antitoxin
DONFEKIO_01252 1.3e-243 S HipA-like C-terminal domain
DONFEKIO_01253 5.6e-18 higA K Helix-turn-helix
DONFEKIO_01254 8.9e-221 G Transmembrane secretion effector
DONFEKIO_01255 1.2e-118 K Bacterial regulatory proteins, tetR family
DONFEKIO_01256 5.9e-12
DONFEKIO_01257 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
DONFEKIO_01258 1.2e-13 EGP Transmembrane secretion effector
DONFEKIO_01259 3e-290 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DONFEKIO_01260 2.8e-243 nagA 3.5.1.25 G Amidohydrolase family
DONFEKIO_01261 1.9e-147 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DONFEKIO_01262 8.7e-176 2.7.1.2 GK ROK family
DONFEKIO_01263 3.1e-220 GK ROK family
DONFEKIO_01264 6.4e-159 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
DONFEKIO_01265 7.5e-253 gtr U Sugar (and other) transporter
DONFEKIO_01266 0.0 P Domain of unknown function (DUF4976)
DONFEKIO_01267 1.2e-271 aslB C Iron-sulfur cluster-binding domain
DONFEKIO_01268 3.2e-107 S Sulfite exporter TauE/SafE
DONFEKIO_01269 2.9e-57 L Helix-turn-helix domain
DONFEKIO_01270 8.9e-94 S Sulfite exporter TauE/SafE
DONFEKIO_01271 1.7e-63 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DONFEKIO_01273 1.6e-244 EGP Major facilitator Superfamily
DONFEKIO_01274 3e-107 3.1.3.27 E haloacid dehalogenase-like hydrolase
DONFEKIO_01275 1.4e-161 3.1.3.73 G Phosphoglycerate mutase family
DONFEKIO_01276 1.1e-234 rutG F Permease family
DONFEKIO_01277 4.6e-304 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
DONFEKIO_01278 4.6e-249 nplT G Alpha amylase, catalytic domain
DONFEKIO_01279 3.1e-187 pit P Phosphate transporter family
DONFEKIO_01280 1e-113 MA20_27875 P Protein of unknown function DUF47
DONFEKIO_01281 5.6e-110 K helix_turn_helix, Lux Regulon
DONFEKIO_01282 9.7e-226 T Histidine kinase
DONFEKIO_01283 1.8e-10 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
DONFEKIO_01284 2.9e-187 V ATPases associated with a variety of cellular activities
DONFEKIO_01285 7.5e-225 V ABC-2 family transporter protein
DONFEKIO_01286 4.2e-251 V ABC-2 family transporter protein
DONFEKIO_01287 4.5e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DONFEKIO_01288 3.2e-112 E GDSL-like Lipase/Acylhydrolase family
DONFEKIO_01289 7e-191
DONFEKIO_01290 1.2e-109 3.4.13.21 E Peptidase family S51
DONFEKIO_01291 2.4e-110 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
DONFEKIO_01292 7.6e-161 M pfam nlp p60
DONFEKIO_01293 3.3e-152 I Serine aminopeptidase, S33
DONFEKIO_01294 1.4e-30 yozG K Cro/C1-type HTH DNA-binding domain
DONFEKIO_01295 1.7e-53 S Protein of unknown function (DUF2975)
DONFEKIO_01296 1.3e-241 pbuX F Permease family
DONFEKIO_01297 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DONFEKIO_01298 0.0 pcrA 3.6.4.12 L DNA helicase
DONFEKIO_01299 3.4e-62 S Domain of unknown function (DUF4418)
DONFEKIO_01300 5.1e-218 V FtsX-like permease family
DONFEKIO_01301 9.7e-161 lolD V ABC transporter
DONFEKIO_01302 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DONFEKIO_01303 1.7e-153 S Peptidase C26
DONFEKIO_01304 2.5e-91 3.5.4.5 F cytidine deaminase activity
DONFEKIO_01305 1.8e-46 sdpI S SdpI/YhfL protein family
DONFEKIO_01306 1.2e-111 E Transglutaminase-like superfamily
DONFEKIO_01307 7.1e-67 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
DONFEKIO_01308 1.2e-48 relB L RelB antitoxin
DONFEKIO_01309 1.9e-129 pgm3 G Phosphoglycerate mutase family
DONFEKIO_01310 2.4e-55 WQ51_05790 S Bacterial protein of unknown function (DUF948)
DONFEKIO_01311 1.6e-35
DONFEKIO_01312 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DONFEKIO_01313 2.7e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DONFEKIO_01314 5.4e-196 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DONFEKIO_01315 4.1e-70 3.4.23.43 S Type IV leader peptidase family
DONFEKIO_01316 7.3e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DONFEKIO_01317 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DONFEKIO_01318 1.3e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
DONFEKIO_01319 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DONFEKIO_01320 0.0 S L,D-transpeptidase catalytic domain
DONFEKIO_01321 1.5e-291 sufB O FeS assembly protein SufB
DONFEKIO_01322 1.2e-235 sufD O FeS assembly protein SufD
DONFEKIO_01323 7e-144 sufC O FeS assembly ATPase SufC
DONFEKIO_01324 2.5e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DONFEKIO_01325 8.1e-102 iscU C SUF system FeS assembly protein, NifU family
DONFEKIO_01326 3.2e-109 yitW S Iron-sulfur cluster assembly protein
DONFEKIO_01327 6.2e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DONFEKIO_01328 3.3e-166 spoU 2.1.1.185 J SpoU rRNA Methylase family
DONFEKIO_01330 3e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DONFEKIO_01331 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
DONFEKIO_01332 4.2e-217 phoH T PhoH-like protein
DONFEKIO_01333 4.7e-102 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DONFEKIO_01334 5.6e-248 corC S CBS domain
DONFEKIO_01335 4.3e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DONFEKIO_01336 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DONFEKIO_01337 4.8e-205 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
DONFEKIO_01338 2.1e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
DONFEKIO_01339 5.1e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DONFEKIO_01340 4.9e-235 yhjX EGP Major facilitator Superfamily
DONFEKIO_01341 1.7e-103 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DONFEKIO_01342 1.6e-226 ilvE 2.6.1.42 E Amino-transferase class IV
DONFEKIO_01343 1.6e-13
DONFEKIO_01344 3.1e-27 S Putative phage holin Dp-1
DONFEKIO_01345 3.6e-110 M Glycosyl hydrolases family 25
DONFEKIO_01346 3.1e-21
DONFEKIO_01351 1.2e-182 ebh 2.1.1.80, 3.1.1.61 S cellulase activity
DONFEKIO_01353 2e-117 MA20_18055 DNT domain protein
DONFEKIO_01356 4.7e-71
DONFEKIO_01359 1.2e-60
DONFEKIO_01360 4e-40
DONFEKIO_01361 2.4e-118 S Phage major capsid protein E
DONFEKIO_01362 1.5e-56
DONFEKIO_01364 4.6e-93
DONFEKIO_01365 9.6e-212
DONFEKIO_01366 0.0 S Terminase
DONFEKIO_01369 7.5e-34 V HNH endonuclease
DONFEKIO_01374 5.6e-14 K Helix-turn-helix domain
DONFEKIO_01385 3.7e-34 relB L RelB antitoxin
DONFEKIO_01386 2.4e-49 T Toxic component of a toxin-antitoxin (TA) module
DONFEKIO_01390 1.4e-151 S Fic/DOC family
DONFEKIO_01396 1.9e-72 K BRO family, N-terminal domain
DONFEKIO_01397 1.6e-35
DONFEKIO_01398 2.9e-31
DONFEKIO_01399 4.2e-27
DONFEKIO_01400 1.5e-51 L HNH endonuclease
DONFEKIO_01402 2.3e-16 S Protein of unknwon function (DUF3310)
DONFEKIO_01408 2.5e-20
DONFEKIO_01412 8.4e-39
DONFEKIO_01413 5.5e-28
DONFEKIO_01420 7.5e-45 D DNA N-6-adenine-methyltransferase (Dam)
DONFEKIO_01421 5.1e-38
DONFEKIO_01426 3.3e-32 V HNH endonuclease
DONFEKIO_01427 1.1e-10 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DONFEKIO_01428 4.3e-07 S ERF superfamily
DONFEKIO_01429 1.1e-70 L PDDEXK-like domain of unknown function (DUF3799)
DONFEKIO_01437 1.4e-17
DONFEKIO_01438 1.6e-22
DONFEKIO_01441 9.5e-17
DONFEKIO_01442 4.6e-52 gepA S Protein of unknown function (DUF4065)
DONFEKIO_01443 3.1e-58 int L Phage integrase family
DONFEKIO_01446 2.5e-27 D FtsK/SpoIIIE family
DONFEKIO_01447 1.1e-61
DONFEKIO_01448 5.1e-83 L Restriction endonuclease BglII
DONFEKIO_01449 1.4e-98 KT MT-A70
DONFEKIO_01450 7.2e-194 S Psort location CytoplasmicMembrane, score
DONFEKIO_01451 9.6e-258 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DONFEKIO_01453 1.1e-206 V VanZ like family
DONFEKIO_01454 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DONFEKIO_01455 4.2e-15 lacS G Psort location CytoplasmicMembrane, score 10.00
DONFEKIO_01456 2.6e-183 lacR K Transcriptional regulator, LacI family
DONFEKIO_01457 1.4e-50 S Transmembrane domain of unknown function (DUF3566)
DONFEKIO_01458 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DONFEKIO_01459 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DONFEKIO_01460 4.2e-83 S Protein of unknown function (DUF721)
DONFEKIO_01461 2.2e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DONFEKIO_01462 1.9e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DONFEKIO_01463 3.3e-280 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DONFEKIO_01464 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DONFEKIO_01465 1.6e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DONFEKIO_01466 5.8e-183 yidC U Membrane protein insertase, YidC Oxa1 family
DONFEKIO_01467 6.6e-93 jag S Putative single-stranded nucleic acids-binding domain
DONFEKIO_01468 1.2e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DONFEKIO_01469 1.1e-173 parA D CobQ CobB MinD ParA nucleotide binding domain protein
DONFEKIO_01470 1.4e-221 parB K Belongs to the ParB family
DONFEKIO_01471 1.2e-175 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DONFEKIO_01472 0.0 murJ KLT MviN-like protein
DONFEKIO_01473 0.0
DONFEKIO_01474 9e-165 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
DONFEKIO_01475 3.2e-283 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
DONFEKIO_01476 1.8e-110 S LytR cell envelope-related transcriptional attenuator
DONFEKIO_01477 8.5e-176 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DONFEKIO_01478 6.4e-168 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DONFEKIO_01479 4.5e-216 S G5
DONFEKIO_01481 4.2e-138 O Thioredoxin
DONFEKIO_01482 0.0 KLT Protein tyrosine kinase
DONFEKIO_01483 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
DONFEKIO_01484 2.9e-42 kcsA U Ion channel
DONFEKIO_01485 6.8e-127 S Protein of unknown function (DUF3990)
DONFEKIO_01486 8.5e-119 K Helix-turn-helix XRE-family like proteins
DONFEKIO_01487 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
DONFEKIO_01488 2.8e-122 S Psort location CytoplasmicMembrane, score
DONFEKIO_01489 3.1e-43 nrdH O Glutaredoxin
DONFEKIO_01490 1.6e-88 nrdI F Probably involved in ribonucleotide reductase function
DONFEKIO_01491 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DONFEKIO_01493 1.3e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DONFEKIO_01494 3.2e-229 T GHKL domain
DONFEKIO_01495 5.1e-142 K LytTr DNA-binding domain
DONFEKIO_01496 1.4e-220 2.4.1.166 GT2 M Glycosyltransferase like family 2
DONFEKIO_01497 2.1e-73 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DONFEKIO_01498 1.4e-44 ulaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
DONFEKIO_01499 4.9e-241 ulaA 2.7.1.194 S PTS system sugar-specific permease component
DONFEKIO_01500 3e-136 K UTRA domain
DONFEKIO_01501 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
DONFEKIO_01502 6.2e-48 S LPXTG-motif cell wall anchor domain protein
DONFEKIO_01503 1.2e-146 tnp3514b L Winged helix-turn helix
DONFEKIO_01504 1e-185
DONFEKIO_01505 5e-142 U Branched-chain amino acid transport system / permease component
DONFEKIO_01506 8.7e-178 3.6.3.17 G ATPases associated with a variety of cellular activities
DONFEKIO_01507 4.2e-146 G Periplasmic binding protein domain
DONFEKIO_01508 1.1e-131 K helix_turn _helix lactose operon repressor
DONFEKIO_01509 7.6e-18 tnp7109-21 L Integrase core domain
DONFEKIO_01510 4.4e-155
DONFEKIO_01511 1.6e-271 KLT Domain of unknown function (DUF4032)
DONFEKIO_01512 4.2e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DONFEKIO_01513 5.9e-168 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
DONFEKIO_01514 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DONFEKIO_01515 3.5e-206 EGP Major facilitator Superfamily
DONFEKIO_01516 6e-288 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
DONFEKIO_01517 7.5e-86 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DONFEKIO_01518 2e-16 K helix_turn _helix lactose operon repressor
DONFEKIO_01519 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
DONFEKIO_01520 2e-37
DONFEKIO_01521 2.2e-110 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
DONFEKIO_01522 1.4e-153
DONFEKIO_01523 8.1e-145 ypfH S Phospholipase/Carboxylesterase
DONFEKIO_01524 2.5e-120 S membrane transporter protein
DONFEKIO_01525 0.0 yjcE P Sodium/hydrogen exchanger family
DONFEKIO_01526 8.3e-78 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DONFEKIO_01527 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
DONFEKIO_01528 1.7e-229 nagC GK ROK family
DONFEKIO_01529 2.3e-245 msmE7 G Bacterial extracellular solute-binding protein
DONFEKIO_01530 8.8e-149 malC G Binding-protein-dependent transport system inner membrane component
DONFEKIO_01531 2.9e-154 G Binding-protein-dependent transport system inner membrane component
DONFEKIO_01532 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DONFEKIO_01533 1.5e-231 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
DONFEKIO_01534 3.6e-145 cobB2 K Sir2 family
DONFEKIO_01535 7.4e-25
DONFEKIO_01536 7.4e-30 L PFAM Integrase catalytic
DONFEKIO_01537 8.5e-44 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
DONFEKIO_01538 2.4e-32 relB L RelB antitoxin
DONFEKIO_01539 4.4e-280 argH 4.3.2.1 E argininosuccinate lyase
DONFEKIO_01540 1.2e-28 thiS 2.8.1.10 H ThiS family
DONFEKIO_01541 3.6e-157 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DONFEKIO_01542 6e-146 moeB 2.7.7.80 H ThiF family
DONFEKIO_01543 3.1e-71 M1-798 P Rhodanese Homology Domain
DONFEKIO_01544 4.6e-102 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
DONFEKIO_01545 7.4e-138 S Putative ABC-transporter type IV
DONFEKIO_01546 3.1e-239 S Protein of unknown function (DUF975)
DONFEKIO_01547 2.6e-255 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DONFEKIO_01548 1.1e-166 L Tetratricopeptide repeat
DONFEKIO_01549 9.3e-200 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
DONFEKIO_01551 1.4e-139 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DONFEKIO_01552 4.7e-96
DONFEKIO_01553 4e-69 trkA P TrkA-N domain
DONFEKIO_01554 8.3e-12 trkB P Cation transport protein
DONFEKIO_01555 7.4e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DONFEKIO_01556 0.0 recN L May be involved in recombinational repair of damaged DNA
DONFEKIO_01557 3.2e-118 S Haloacid dehalogenase-like hydrolase
DONFEKIO_01558 3.6e-56 J Acetyltransferase (GNAT) domain
DONFEKIO_01559 4.8e-58 K helix_turn_helix gluconate operon transcriptional repressor
DONFEKIO_01560 8.5e-173 V ATPases associated with a variety of cellular activities
DONFEKIO_01561 2.9e-120 S ABC-2 family transporter protein
DONFEKIO_01562 3.7e-107
DONFEKIO_01563 1.2e-40 S Psort location Cytoplasmic, score
DONFEKIO_01564 7.3e-283 thrC 4.2.3.1 E Threonine synthase N terminus
DONFEKIO_01565 7.1e-234 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DONFEKIO_01566 4.7e-97
DONFEKIO_01567 3.2e-138 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DONFEKIO_01568 3.3e-92 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
DONFEKIO_01569 1.9e-23 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
DONFEKIO_01570 0.0 S Uncharacterised protein family (UPF0182)
DONFEKIO_01571 4.1e-93 2.3.1.183 M Acetyltransferase (GNAT) domain
DONFEKIO_01572 1.5e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DONFEKIO_01573 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DONFEKIO_01574 7.9e-179 1.1.1.65 C Aldo/keto reductase family
DONFEKIO_01575 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DONFEKIO_01576 6.6e-70 divIC D Septum formation initiator
DONFEKIO_01577 1.3e-102 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
DONFEKIO_01578 1.3e-182 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DONFEKIO_01580 5.4e-93
DONFEKIO_01581 3e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
DONFEKIO_01582 1.4e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
DONFEKIO_01583 4.4e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DONFEKIO_01584 3.1e-146 yplQ S Haemolysin-III related
DONFEKIO_01585 1.1e-278 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DONFEKIO_01586 4.9e-47 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DONFEKIO_01587 0.0 D FtsK/SpoIIIE family
DONFEKIO_01588 7.4e-202 K Cell envelope-related transcriptional attenuator domain
DONFEKIO_01589 1.8e-55 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DONFEKIO_01590 0.0 S Glycosyl transferase, family 2
DONFEKIO_01591 1.6e-261
DONFEKIO_01592 6.3e-78 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
DONFEKIO_01593 2.2e-148 cof 5.2.1.8 T Eukaryotic phosphomannomutase
DONFEKIO_01594 1.5e-129 ctsW S Phosphoribosyl transferase domain
DONFEKIO_01595 4.4e-197 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DONFEKIO_01596 2.9e-128 T Response regulator receiver domain protein
DONFEKIO_01597 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DONFEKIO_01598 2.1e-100 carD K CarD-like/TRCF domain
DONFEKIO_01599 1.1e-87 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DONFEKIO_01600 9.8e-136 znuB U ABC 3 transport family
DONFEKIO_01601 3.8e-162 znuC P ATPases associated with a variety of cellular activities
DONFEKIO_01602 8e-184 P Zinc-uptake complex component A periplasmic
DONFEKIO_01603 1.5e-163 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DONFEKIO_01604 3.2e-254 rpsA J Ribosomal protein S1
DONFEKIO_01605 1.6e-115 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DONFEKIO_01606 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DONFEKIO_01607 1.5e-175 terC P Integral membrane protein, TerC family
DONFEKIO_01608 2.7e-274 pyk 2.7.1.40 G Pyruvate kinase
DONFEKIO_01609 1.1e-109 aspA 3.6.1.13 L NUDIX domain
DONFEKIO_01611 8.2e-124 pdtaR T Response regulator receiver domain protein
DONFEKIO_01612 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DONFEKIO_01613 4.7e-179 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
DONFEKIO_01614 1.5e-126 3.6.1.13 L NUDIX domain
DONFEKIO_01615 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DONFEKIO_01616 4.9e-25 zntR K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
DONFEKIO_01617 1.1e-89 K Putative zinc ribbon domain
DONFEKIO_01618 2.1e-125 S GyrI-like small molecule binding domain
DONFEKIO_01619 5.6e-21 tag 3.2.2.20 L Methyladenine glycosylase
DONFEKIO_01621 1.8e-26 S Polyketide cyclase / dehydrase and lipid transport
DONFEKIO_01623 5.9e-123
DONFEKIO_01624 1.9e-214 ykiI
DONFEKIO_01625 1.3e-251 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DONFEKIO_01626 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DONFEKIO_01627 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DONFEKIO_01629 3.2e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DONFEKIO_01630 0.0 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
DONFEKIO_01631 1.1e-118
DONFEKIO_01632 1.7e-48
DONFEKIO_01635 2.1e-125 O AAA domain (Cdc48 subfamily)
DONFEKIO_01636 1.7e-65
DONFEKIO_01638 5.3e-38 L Phage integrase, N-terminal SAM-like domain
DONFEKIO_01639 1.3e-301 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DONFEKIO_01640 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
DONFEKIO_01641 1.5e-186 K Periplasmic binding protein domain
DONFEKIO_01642 1.1e-141 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
DONFEKIO_01643 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DONFEKIO_01644 1.4e-150 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
DONFEKIO_01645 1.6e-153 yecS E Binding-protein-dependent transport system inner membrane component
DONFEKIO_01646 1.3e-168 pknD ET ABC transporter, substrate-binding protein, family 3
DONFEKIO_01647 5.6e-143 pknD ET ABC transporter, substrate-binding protein, family 3
DONFEKIO_01648 6.3e-79 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DONFEKIO_01649 4e-147 usp 3.5.1.28 CBM50 D CHAP domain protein
DONFEKIO_01650 9.8e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
DONFEKIO_01651 1.3e-202 ftsE D Cell division ATP-binding protein FtsE
DONFEKIO_01652 1.6e-205 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DONFEKIO_01653 3.9e-265 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
DONFEKIO_01654 7.5e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DONFEKIO_01655 1.2e-258 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DONFEKIO_01656 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
DONFEKIO_01657 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DONFEKIO_01658 1.5e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DONFEKIO_01659 6.4e-134 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DONFEKIO_01660 1.2e-233 G Major Facilitator Superfamily
DONFEKIO_01661 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
DONFEKIO_01662 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
DONFEKIO_01663 1.8e-220 KLT Protein tyrosine kinase
DONFEKIO_01664 0.0 S Fibronectin type 3 domain
DONFEKIO_01665 2.5e-239 S Protein of unknown function DUF58
DONFEKIO_01666 0.0 E Transglutaminase-like superfamily
DONFEKIO_01667 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DONFEKIO_01668 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DONFEKIO_01669 2.3e-128
DONFEKIO_01670 7e-186 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
DONFEKIO_01671 7.6e-115 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DONFEKIO_01672 3.2e-253 S UPF0210 protein
DONFEKIO_01673 6.4e-44 gcvR T Belongs to the UPF0237 family
DONFEKIO_01674 2e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
DONFEKIO_01675 6.6e-253 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
DONFEKIO_01676 2.8e-123 glpR K DeoR C terminal sensor domain
DONFEKIO_01677 8e-229 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
DONFEKIO_01678 5.7e-231 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
DONFEKIO_01679 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DONFEKIO_01680 2.1e-134 glxR K helix_turn_helix, cAMP Regulatory protein
DONFEKIO_01681 8.4e-218 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
DONFEKIO_01682 1.8e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DONFEKIO_01683 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
DONFEKIO_01684 5.5e-225 S Uncharacterized conserved protein (DUF2183)
DONFEKIO_01685 5.9e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
DONFEKIO_01686 4.4e-212 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
DONFEKIO_01687 1.4e-158 mhpC I Alpha/beta hydrolase family
DONFEKIO_01688 1.6e-120 F Domain of unknown function (DUF4916)
DONFEKIO_01689 1.9e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
DONFEKIO_01690 8.8e-160 S G5
DONFEKIO_01691 1.2e-162
DONFEKIO_01692 3.4e-237 wcoI DM Psort location CytoplasmicMembrane, score
DONFEKIO_01693 2.4e-69
DONFEKIO_01694 6.9e-245 S Psort location CytoplasmicMembrane, score 9.99
DONFEKIO_01695 5.8e-12 L transposase and inactivated derivatives, IS30 family
DONFEKIO_01696 2.5e-39 S Protein of unknown function (DUF3800)
DONFEKIO_01697 2.9e-30 L PFAM Integrase catalytic
DONFEKIO_01698 3e-67
DONFEKIO_01699 1.4e-86
DONFEKIO_01700 5e-21 L PFAM Integrase catalytic
DONFEKIO_01701 1.4e-10 L HTH-like domain
DONFEKIO_01703 3.9e-07
DONFEKIO_01704 1.2e-25 L Transposase, Mutator family
DONFEKIO_01705 4.1e-172 L PFAM Integrase catalytic
DONFEKIO_01706 1.6e-63 L PFAM Integrase catalytic
DONFEKIO_01707 0.0 T Diguanylate cyclase, GGDEF domain
DONFEKIO_01708 7.1e-136 ybbM V Uncharacterised protein family (UPF0014)
DONFEKIO_01709 4.2e-127 ybbL V ATPases associated with a variety of cellular activities
DONFEKIO_01710 3.9e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DONFEKIO_01711 1.1e-92 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DONFEKIO_01712 2e-241 carA 6.3.5.5 F Belongs to the CarA family
DONFEKIO_01713 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
DONFEKIO_01714 1.5e-169 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DONFEKIO_01715 1.4e-104 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DONFEKIO_01716 8.3e-136 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
DONFEKIO_01718 0.0 tetP J Elongation factor G, domain IV
DONFEKIO_01719 1.9e-126 ypfH S Phospholipase/Carboxylesterase
DONFEKIO_01720 4.9e-108 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DONFEKIO_01721 2.8e-108 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DONFEKIO_01722 2.5e-42 XAC3035 O Glutaredoxin
DONFEKIO_01723 2.7e-08 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
DONFEKIO_01724 7.2e-116 XK27_08050 O prohibitin homologues
DONFEKIO_01725 1.1e-58 S Domain of unknown function (DUF4143)
DONFEKIO_01726 2.9e-159 S Patatin-like phospholipase
DONFEKIO_01727 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DONFEKIO_01728 2.7e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
DONFEKIO_01729 1e-125 S Vitamin K epoxide reductase
DONFEKIO_01730 6.5e-170 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
DONFEKIO_01731 7.2e-33 S Protein of unknown function (DUF3107)
DONFEKIO_01732 2e-302 mphA S Aminoglycoside phosphotransferase
DONFEKIO_01733 4e-292 uvrD2 3.6.4.12 L DNA helicase
DONFEKIO_01734 3.9e-296 S Zincin-like metallopeptidase
DONFEKIO_01735 1.6e-155 lon T Belongs to the peptidase S16 family
DONFEKIO_01736 1.6e-73 S Protein of unknown function (DUF3052)
DONFEKIO_01738 8.8e-210 2.7.11.1 NU Tfp pilus assembly protein FimV
DONFEKIO_01739 3.2e-220 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DONFEKIO_01740 5.3e-231 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DONFEKIO_01741 0.0 I acetylesterase activity
DONFEKIO_01742 4.5e-129 recO L Involved in DNA repair and RecF pathway recombination
DONFEKIO_01743 3.1e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DONFEKIO_01744 4.5e-135 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
DONFEKIO_01745 5.2e-190 P NMT1/THI5 like
DONFEKIO_01746 6.7e-226 E Aminotransferase class I and II
DONFEKIO_01747 4.3e-141 bioM P ATPases associated with a variety of cellular activities
DONFEKIO_01749 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DONFEKIO_01750 0.0 S Tetratricopeptide repeat
DONFEKIO_01751 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DONFEKIO_01752 6e-205 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DONFEKIO_01753 2.3e-281 glnA 6.3.1.2 E glutamine synthetase
DONFEKIO_01754 2.1e-143 S Domain of unknown function (DUF4191)
DONFEKIO_01755 2.1e-277 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DONFEKIO_01756 6.9e-102 S Protein of unknown function (DUF3043)
DONFEKIO_01757 4e-259 argE E Peptidase dimerisation domain
DONFEKIO_01758 6.2e-108 ykoE S ABC-type cobalt transport system, permease component
DONFEKIO_01759 1.3e-279 ykoD P ATPases associated with a variety of cellular activities
DONFEKIO_01760 1.2e-158 cbiQ P Cobalt transport protein
DONFEKIO_01761 6e-160 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DONFEKIO_01762 1.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DONFEKIO_01763 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
DONFEKIO_01764 7.1e-105
DONFEKIO_01765 1e-201 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DONFEKIO_01766 1.2e-211 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DONFEKIO_01767 2.2e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DONFEKIO_01768 3.2e-250 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
DONFEKIO_01769 3.9e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DONFEKIO_01770 5.9e-83 argR K Regulates arginine biosynthesis genes
DONFEKIO_01771 1.2e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DONFEKIO_01772 1.2e-28 L Helix-turn-helix domain
DONFEKIO_01773 1.4e-182 P NMT1/THI5 like
DONFEKIO_01774 1.2e-146 P ATPases associated with a variety of cellular activities
DONFEKIO_01775 5.2e-115 U Binding-protein-dependent transport system inner membrane component
DONFEKIO_01776 1.9e-128 P Binding-protein-dependent transport systems inner membrane component
DONFEKIO_01777 2.5e-239 Q Amidohydrolase family
DONFEKIO_01778 2.5e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DONFEKIO_01779 5e-145 P ATPases associated with a variety of cellular activities
DONFEKIO_01780 1.3e-162 P ATPases associated with a variety of cellular activities
DONFEKIO_01781 4.5e-127 P Cobalt transport protein
DONFEKIO_01782 6.6e-89 2.7.7.65 T ECF transporter, substrate-specific component
DONFEKIO_01783 5.2e-170 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DONFEKIO_01784 1.5e-175 rbsR K helix_turn _helix lactose operon repressor
DONFEKIO_01785 8e-24 lacS G Psort location CytoplasmicMembrane, score 10.00
DONFEKIO_01787 0.0 V ABC transporter transmembrane region
DONFEKIO_01788 0.0 V ABC transporter, ATP-binding protein
DONFEKIO_01789 7.1e-87 K MarR family
DONFEKIO_01790 6.4e-176 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
DONFEKIO_01791 4e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
DONFEKIO_01792 1.3e-69 S Nucleotidyltransferase substrate binding protein like
DONFEKIO_01793 6.1e-45 S Nucleotidyltransferase domain
DONFEKIO_01795 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
DONFEKIO_01796 2.3e-141 K Bacterial regulatory proteins, tetR family
DONFEKIO_01797 1.2e-254 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
DONFEKIO_01798 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
DONFEKIO_01799 5e-136 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DONFEKIO_01800 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
DONFEKIO_01801 1.8e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DONFEKIO_01802 3.7e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DONFEKIO_01803 4.6e-91 ywrO 1.6.5.2 S Flavodoxin-like fold
DONFEKIO_01804 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DONFEKIO_01805 3.2e-65 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DONFEKIO_01806 3.1e-77 F Nucleoside 2-deoxyribosyltransferase
DONFEKIO_01808 1.6e-200 S Endonuclease/Exonuclease/phosphatase family
DONFEKIO_01809 3.4e-180 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DONFEKIO_01810 3e-234 aspB E Aminotransferase class-V
DONFEKIO_01811 2.2e-201 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
DONFEKIO_01812 2.2e-87 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
DONFEKIO_01813 1.2e-100 XK27_03610 K Acetyltransferase (GNAT) domain
DONFEKIO_01814 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
DONFEKIO_01815 4e-147 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
DONFEKIO_01816 2.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
DONFEKIO_01817 6e-151 map 3.4.11.18 E Methionine aminopeptidase
DONFEKIO_01818 5.2e-143 S Short repeat of unknown function (DUF308)
DONFEKIO_01819 0.0 pepO 3.4.24.71 O Peptidase family M13
DONFEKIO_01820 2.4e-116 L Single-strand binding protein family
DONFEKIO_01821 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DONFEKIO_01822 2.2e-100 pflA 1.97.1.4 O Radical SAM superfamily
DONFEKIO_01823 1.4e-262 recD2 3.6.4.12 L PIF1-like helicase
DONFEKIO_01824 7e-121 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
DONFEKIO_01825 1e-139 K Periplasmic binding protein-like domain
DONFEKIO_01826 9.4e-256 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
DONFEKIO_01827 6.8e-181 G Transporter major facilitator family protein
DONFEKIO_01828 3.2e-261 G Bacterial extracellular solute-binding protein
DONFEKIO_01829 0.0 cydD V ABC transporter transmembrane region
DONFEKIO_01831 1.7e-20 araE EGP Major facilitator Superfamily
DONFEKIO_01832 1.1e-40 araE EGP Major facilitator Superfamily
DONFEKIO_01833 1.3e-34 fadD 6.2.1.3 I AMP-binding enzyme
DONFEKIO_01834 4.4e-291 fadD 6.2.1.3 I AMP-binding enzyme
DONFEKIO_01835 1.2e-210 K helix_turn _helix lactose operon repressor
DONFEKIO_01836 1.4e-158 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DONFEKIO_01837 3.8e-165 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DONFEKIO_01838 8.1e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DONFEKIO_01840 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
DONFEKIO_01841 9.4e-264 abcT3 P ATPases associated with a variety of cellular activities
DONFEKIO_01842 0.0 pgi 5.3.1.9 G Belongs to the GPI family
DONFEKIO_01845 1.4e-176 S Auxin Efflux Carrier
DONFEKIO_01846 1.3e-137 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DONFEKIO_01847 1.1e-144 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DONFEKIO_01848 2.8e-249 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DONFEKIO_01849 3.7e-119
DONFEKIO_01850 1.1e-77 soxR K MerR, DNA binding
DONFEKIO_01851 1.6e-196 yghZ C Aldo/keto reductase family
DONFEKIO_01852 2.4e-49 S Protein of unknown function (DUF3039)
DONFEKIO_01853 6e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DONFEKIO_01854 3.6e-71
DONFEKIO_01855 7.6e-117 yceD S Uncharacterized ACR, COG1399
DONFEKIO_01856 9.3e-21 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DONFEKIO_01857 9.7e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DONFEKIO_01858 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
DONFEKIO_01859 4e-93 ilvN 2.2.1.6 E ACT domain
DONFEKIO_01860 3.9e-44 stbC S Plasmid stability protein
DONFEKIO_01861 3.9e-72 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
DONFEKIO_01862 0.0 yjjK S ABC transporter
DONFEKIO_01863 9.5e-135 guaA1 6.3.5.2 F Peptidase C26
DONFEKIO_01864 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
DONFEKIO_01865 1.9e-161 P Cation efflux family
DONFEKIO_01866 1.8e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DONFEKIO_01867 4.2e-205 S Endonuclease/Exonuclease/phosphatase family
DONFEKIO_01868 5.6e-62 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DONFEKIO_01869 1e-34 CP_0960 S Belongs to the UPF0109 family
DONFEKIO_01870 2.2e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DONFEKIO_01871 4.2e-200 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DONFEKIO_01872 7e-169 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
DONFEKIO_01873 1.5e-19
DONFEKIO_01874 3.8e-91 S Predicted membrane protein (DUF2207)
DONFEKIO_01875 2.2e-103 S Predicted membrane protein (DUF2207)
DONFEKIO_01876 1.9e-10 S Predicted membrane protein (DUF2207)
DONFEKIO_01877 0.0 S Predicted membrane protein (DUF2207)
DONFEKIO_01878 4.9e-89 lemA S LemA family
DONFEKIO_01879 2.4e-34 macB_7 V FtsX-like permease family
DONFEKIO_01880 8.7e-117 V ABC transporter, ATP-binding protein
DONFEKIO_01881 8.8e-16 fic D Fic/DOC family
DONFEKIO_01882 4.1e-23
DONFEKIO_01883 3.5e-109
DONFEKIO_01884 1.3e-45 K sequence-specific DNA binding
DONFEKIO_01885 8.3e-34 hipA 2.7.11.1 S kinase activity
DONFEKIO_01886 4.4e-42 2.6.1.76 EGP Major Facilitator Superfamily
DONFEKIO_01887 6.3e-20 G Major facilitator Superfamily
DONFEKIO_01888 8.3e-293 mmuP E amino acid
DONFEKIO_01890 7.4e-64 yeaO K Protein of unknown function, DUF488
DONFEKIO_01891 1.3e-75
DONFEKIO_01892 7.4e-170 3.6.4.12
DONFEKIO_01893 2e-93 yijF S Domain of unknown function (DUF1287)
DONFEKIO_01894 6.4e-298 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DONFEKIO_01895 5.3e-71 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DONFEKIO_01896 6.1e-140 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DONFEKIO_01897 3.6e-76 3.5.1.124 S DJ-1/PfpI family
DONFEKIO_01898 6.7e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DONFEKIO_01899 3.7e-174 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
DONFEKIO_01900 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DONFEKIO_01901 2.8e-134 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DONFEKIO_01902 1.4e-145 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DONFEKIO_01903 2.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
DONFEKIO_01904 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DONFEKIO_01905 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
DONFEKIO_01906 3.3e-91
DONFEKIO_01907 1.5e-208 guaB 1.1.1.205 F IMP dehydrogenase family protein
DONFEKIO_01908 4.6e-243 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
DONFEKIO_01909 1e-256 G ABC transporter substrate-binding protein
DONFEKIO_01910 2e-35 M Peptidase family M23
DONFEKIO_01912 3.9e-52 xerH L Phage integrase family
DONFEKIO_01913 1.5e-124 2.7.11.1 S HipA-like C-terminal domain
DONFEKIO_01917 2.7e-143 S Fic/DOC family
DONFEKIO_01918 5.3e-136 L PFAM Relaxase mobilization nuclease family protein
DONFEKIO_01919 5.8e-87 2.7.11.1 S HipA-like C-terminal domain
DONFEKIO_01921 8.9e-39
DONFEKIO_01922 1.2e-49 S Domain of unknown function (DUF4913)
DONFEKIO_01923 1.2e-231 U TraM recognition site of TraD and TraG
DONFEKIO_01924 2.5e-22
DONFEKIO_01925 7.4e-08
DONFEKIO_01928 5.7e-201 traD S COG0433 Predicted ATPase
DONFEKIO_01929 1.4e-185
DONFEKIO_01930 9.9e-142
DONFEKIO_01931 1.7e-29
DONFEKIO_01932 2.6e-32
DONFEKIO_01933 6.7e-08
DONFEKIO_01934 8e-21
DONFEKIO_01935 0.0 XK27_00515 D Cell surface antigen C-terminus
DONFEKIO_01936 6.3e-38
DONFEKIO_01937 1.3e-252 U Spy0128-like isopeptide containing domain
DONFEKIO_01938 6.6e-38
DONFEKIO_01939 4.3e-17
DONFEKIO_01941 1e-30 parA D VirC1 protein
DONFEKIO_01942 1.7e-15 S Transcription factor WhiB
DONFEKIO_01943 4.9e-15 S Helix-turn-helix domain
DONFEKIO_01948 3.8e-10
DONFEKIO_01950 6.2e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DONFEKIO_01951 3.8e-105 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
DONFEKIO_01952 1e-159 yeaZ 2.3.1.234 O Glycoprotease family
DONFEKIO_01953 4e-88 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
DONFEKIO_01954 9e-173 holA 2.7.7.7 L DNA polymerase III delta subunit
DONFEKIO_01955 2.6e-308 comE S Competence protein
DONFEKIO_01956 1.6e-44 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
DONFEKIO_01957 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DONFEKIO_01958 6.1e-160 ET Bacterial periplasmic substrate-binding proteins
DONFEKIO_01959 5.3e-170 corA P CorA-like Mg2+ transporter protein
DONFEKIO_01960 5.4e-166 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DONFEKIO_01961 1.2e-233 L ribosomal rna small subunit methyltransferase
DONFEKIO_01962 9.2e-71 pdxH S Pfam:Pyridox_oxidase
DONFEKIO_01963 1.8e-170 EG EamA-like transporter family
DONFEKIO_01964 2.1e-131 C Putative TM nitroreductase
DONFEKIO_01965 4.3e-31
DONFEKIO_01966 7.8e-257 S Metal-independent alpha-mannosidase (GH125)
DONFEKIO_01967 6.8e-242 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
DONFEKIO_01968 1e-41 L Transposase, Mutator family
DONFEKIO_01969 1.9e-105 K Bacterial regulatory proteins, tetR family
DONFEKIO_01970 1.9e-258 MA20_36090 S Psort location Cytoplasmic, score 8.87
DONFEKIO_01971 1.2e-85 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DONFEKIO_01972 2e-80 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DONFEKIO_01973 3.3e-71 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
DONFEKIO_01974 4.4e-17 P Sodium/hydrogen exchanger family
DONFEKIO_01976 1e-80
DONFEKIO_01977 0.0 1.3.98.1, 3.2.1.21 GH3 M Conserved repeat domain
DONFEKIO_01978 9e-276 M LPXTG cell wall anchor motif
DONFEKIO_01980 1.2e-50
DONFEKIO_01981 1.7e-18
DONFEKIO_01982 7.6e-110
DONFEKIO_01983 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DONFEKIO_01984 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DONFEKIO_01985 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DONFEKIO_01986 1.5e-189 K helix_turn _helix lactose operon repressor
DONFEKIO_01987 2.5e-87 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
DONFEKIO_01988 2.9e-142 L Protein of unknown function (DUF1524)
DONFEKIO_01989 1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
DONFEKIO_01990 4.3e-281 EGP Major facilitator Superfamily
DONFEKIO_01991 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
DONFEKIO_01992 6.6e-235 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
DONFEKIO_01993 3.3e-109 3.1.3.48 T Low molecular weight phosphatase family
DONFEKIO_01994 4.6e-114 S Psort location CytoplasmicMembrane, score 9.99
DONFEKIO_01996 2.3e-146 L Transposase and inactivated derivatives IS30 family
DONFEKIO_01997 1.5e-31 L Transposase and inactivated derivatives IS30 family
DONFEKIO_01998 3.6e-148 L IstB-like ATP binding protein
DONFEKIO_01999 2.8e-295 L PFAM Integrase catalytic
DONFEKIO_02000 2.6e-139 M Psort location Cytoplasmic, score 8.87
DONFEKIO_02001 6.6e-52 GT4 M Psort location Cytoplasmic, score 8.87
DONFEKIO_02002 2.6e-07
DONFEKIO_02003 8.9e-63 C Polysaccharide pyruvyl transferase
DONFEKIO_02004 2.9e-119 S Psort location CytoplasmicMembrane, score 9.99
DONFEKIO_02005 7.9e-47 M Glycosyltransferase like family 2
DONFEKIO_02006 5.3e-179 menD 2.2.1.9 H Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DONFEKIO_02007 9e-71 L Transposase, Mutator family
DONFEKIO_02008 3e-208 L PFAM Integrase catalytic
DONFEKIO_02009 0.0 tetP J elongation factor G
DONFEKIO_02010 1.4e-137 K helix_turn _helix lactose operon repressor
DONFEKIO_02011 1.8e-221 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
DONFEKIO_02012 5.9e-125 lacG G Binding-protein-dependent transport system inner membrane component
DONFEKIO_02013 1.3e-123 G Binding-protein-dependent transport system inner membrane component
DONFEKIO_02014 1.1e-178 srrA1 G Bacterial extracellular solute-binding protein
DONFEKIO_02015 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
DONFEKIO_02016 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
DONFEKIO_02017 4.7e-18 L Integrase core domain
DONFEKIO_02018 2.2e-237 S AAA domain
DONFEKIO_02019 1.6e-177 P Binding-protein-dependent transport system inner membrane component
DONFEKIO_02020 2.9e-165 malC P Binding-protein-dependent transport system inner membrane component
DONFEKIO_02021 4.1e-264 G Bacterial extracellular solute-binding protein
DONFEKIO_02022 2.1e-306 Z012_09690 P Domain of unknown function (DUF4976)
DONFEKIO_02023 3.8e-193 K helix_turn _helix lactose operon repressor
DONFEKIO_02024 2.8e-262 aslB C Iron-sulfur cluster-binding domain
DONFEKIO_02025 5.7e-133 S Sulfite exporter TauE/SafE
DONFEKIO_02026 5.8e-296 L PFAM Integrase catalytic
DONFEKIO_02027 4.1e-144 L IstB-like ATP binding protein
DONFEKIO_02028 1.5e-28 pslL G Acyltransferase family
DONFEKIO_02029 5.6e-54 S enterobacterial common antigen metabolic process
DONFEKIO_02030 5.7e-21 G ABC transporter permease
DONFEKIO_02031 8.5e-57 G ABC transporter permease
DONFEKIO_02032 3e-148 malC G Binding-protein-dependent transport system inner membrane component

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)