ORF_ID e_value Gene_name EC_number CAZy COGs Description
HDGFOPHL_00002 7.6e-52 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HDGFOPHL_00003 1.5e-297 dtpT U amino acid peptide transporter
HDGFOPHL_00004 7.2e-149 yjjH S Calcineurin-like phosphoesterase
HDGFOPHL_00007 3e-134 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDGFOPHL_00008 2.4e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDGFOPHL_00009 1.9e-124 gntR1 K UbiC transcription regulator-associated domain protein
HDGFOPHL_00010 9e-92 MA20_25245 K FR47-like protein
HDGFOPHL_00011 4.5e-140 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDGFOPHL_00012 4.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDGFOPHL_00013 3e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDGFOPHL_00014 1.4e-72
HDGFOPHL_00015 0.0 yhgF K Tex-like protein N-terminal domain protein
HDGFOPHL_00016 4e-89 ydcK S Belongs to the SprT family
HDGFOPHL_00017 3.1e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDGFOPHL_00019 1.1e-64 4.1.1.52 S Amidohydrolase
HDGFOPHL_00020 4.4e-73 4.1.1.52 S Amidohydrolase
HDGFOPHL_00021 3.3e-123 S Alpha/beta hydrolase family
HDGFOPHL_00022 4.8e-62 yobS K transcriptional regulator
HDGFOPHL_00023 1.8e-115 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HDGFOPHL_00024 2.6e-98 S Psort location CytoplasmicMembrane, score
HDGFOPHL_00025 1.1e-72 K MarR family
HDGFOPHL_00026 3e-246 dinF V MatE
HDGFOPHL_00027 4.9e-108 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HDGFOPHL_00028 1.6e-54 manL 2.7.1.191 G PTS system fructose IIA component
HDGFOPHL_00029 1.4e-60 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
HDGFOPHL_00030 1.9e-117 manM G PTS system
HDGFOPHL_00031 1.2e-154 manN G system, mannose fructose sorbose family IID component
HDGFOPHL_00032 2.9e-177 K AI-2E family transporter
HDGFOPHL_00033 1.5e-166 2.7.7.65 T diguanylate cyclase
HDGFOPHL_00034 5.5e-118 yliE T EAL domain
HDGFOPHL_00035 2.8e-102 K Bacterial regulatory proteins, tetR family
HDGFOPHL_00036 1e-200 XK27_06930 V domain protein
HDGFOPHL_00037 2.2e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
HDGFOPHL_00038 1.5e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDGFOPHL_00039 7.9e-166 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HDGFOPHL_00040 4.7e-172 EG EamA-like transporter family
HDGFOPHL_00041 5e-122 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDGFOPHL_00042 1.7e-229 V Beta-lactamase
HDGFOPHL_00043 5.6e-258 pepC 3.4.22.40 E Peptidase C1-like family
HDGFOPHL_00045 5.3e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDGFOPHL_00046 2e-55
HDGFOPHL_00047 9.6e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HDGFOPHL_00048 4.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDGFOPHL_00049 4.9e-213 yacL S domain protein
HDGFOPHL_00050 3.1e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDGFOPHL_00051 7.4e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDGFOPHL_00052 7.8e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDGFOPHL_00053 7.4e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDGFOPHL_00054 1.8e-90 yacP S YacP-like NYN domain
HDGFOPHL_00055 4.3e-98 sigH K Sigma-70 region 2
HDGFOPHL_00056 3.3e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDGFOPHL_00057 1.1e-98 nusG K Participates in transcription elongation, termination and antitermination
HDGFOPHL_00058 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDGFOPHL_00059 3.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDGFOPHL_00060 6.9e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDGFOPHL_00061 4e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDGFOPHL_00062 5.8e-94 K Transcriptional regulatory protein, C terminal
HDGFOPHL_00063 2.3e-113 T PhoQ Sensor
HDGFOPHL_00064 1.8e-117 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HDGFOPHL_00065 1.6e-21 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatase
HDGFOPHL_00066 1.2e-192 S membrane
HDGFOPHL_00067 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDGFOPHL_00068 2.4e-109 yvdD 3.2.2.10 S Belongs to the LOG family
HDGFOPHL_00069 3.2e-164 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HDGFOPHL_00070 1.9e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDGFOPHL_00071 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDGFOPHL_00072 6.4e-37 nrdH O Glutaredoxin
HDGFOPHL_00073 1.2e-109 rsmC 2.1.1.172 J Methyltransferase
HDGFOPHL_00074 2.5e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDGFOPHL_00075 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDGFOPHL_00076 3.6e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDGFOPHL_00077 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDGFOPHL_00078 1.3e-38 yaaL S Protein of unknown function (DUF2508)
HDGFOPHL_00079 6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDGFOPHL_00080 2.2e-54 yaaQ S Cyclic-di-AMP receptor
HDGFOPHL_00081 1.5e-178 holB 2.7.7.7 L DNA polymerase III
HDGFOPHL_00082 1.7e-38 yabA L Involved in initiation control of chromosome replication
HDGFOPHL_00083 4.9e-162 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDGFOPHL_00084 5.8e-140 fat 3.1.2.21 I Acyl-ACP thioesterase
HDGFOPHL_00085 1.6e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HDGFOPHL_00086 7.5e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HDGFOPHL_00087 1.4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDGFOPHL_00088 4.8e-213 yeaN P Transporter, major facilitator family protein
HDGFOPHL_00089 7.5e-46 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDGFOPHL_00090 0.0 uup S ABC transporter, ATP-binding protein
HDGFOPHL_00091 2e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDGFOPHL_00092 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDGFOPHL_00093 4.2e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDGFOPHL_00094 0.0 ydaO E amino acid
HDGFOPHL_00095 3.7e-140 lrgB M LrgB-like family
HDGFOPHL_00096 6.1e-60 lrgA S LrgA family
HDGFOPHL_00097 3.6e-178 tagO 2.7.8.33, 2.7.8.35 M transferase
HDGFOPHL_00098 3.5e-112 yvyE 3.4.13.9 S YigZ family
HDGFOPHL_00099 7.7e-252 comFA L Helicase C-terminal domain protein
HDGFOPHL_00100 1.2e-118 comFC S Competence protein
HDGFOPHL_00101 7.9e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDGFOPHL_00102 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDGFOPHL_00103 8e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDGFOPHL_00104 8.3e-218 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HDGFOPHL_00105 2e-129 K response regulator
HDGFOPHL_00106 7.9e-244 phoR 2.7.13.3 T Histidine kinase
HDGFOPHL_00107 5.1e-159 pstS P Phosphate
HDGFOPHL_00108 2e-158 pstC P probably responsible for the translocation of the substrate across the membrane
HDGFOPHL_00109 1e-154 pstA P Phosphate transport system permease protein PstA
HDGFOPHL_00110 1.8e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDGFOPHL_00111 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDGFOPHL_00112 6.8e-119 phoU P Plays a role in the regulation of phosphate uptake
HDGFOPHL_00113 1.7e-54 pspC KT PspC domain protein
HDGFOPHL_00114 1.2e-29 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HDGFOPHL_00115 1.4e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDGFOPHL_00116 1.6e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDGFOPHL_00117 3.4e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HDGFOPHL_00118 5.8e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDGFOPHL_00119 9.9e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDGFOPHL_00121 6.7e-116 yfbR S HD containing hydrolase-like enzyme
HDGFOPHL_00122 1.9e-92 K acetyltransferase
HDGFOPHL_00123 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDGFOPHL_00124 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDGFOPHL_00125 2.4e-90 S Short repeat of unknown function (DUF308)
HDGFOPHL_00126 4.8e-165 rapZ S Displays ATPase and GTPase activities
HDGFOPHL_00127 4.5e-191 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HDGFOPHL_00128 9.9e-169 whiA K May be required for sporulation
HDGFOPHL_00129 2.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDGFOPHL_00130 1.3e-70 XK27_02470 K LytTr DNA-binding domain
HDGFOPHL_00131 1.3e-120 liaI S membrane
HDGFOPHL_00133 1.4e-107 S ECF transporter, substrate-specific component
HDGFOPHL_00135 3.1e-184 cggR K Putative sugar-binding domain
HDGFOPHL_00136 9e-192 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDGFOPHL_00137 4.3e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HDGFOPHL_00138 6.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDGFOPHL_00139 8e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDGFOPHL_00141 6.5e-282 clcA P chloride
HDGFOPHL_00142 4.9e-32 secG U Preprotein translocase
HDGFOPHL_00143 1.6e-137 est 3.1.1.1 S Serine aminopeptidase, S33
HDGFOPHL_00144 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDGFOPHL_00145 2.3e-81 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDGFOPHL_00146 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDGFOPHL_00147 1.7e-99 yxjI
HDGFOPHL_00148 3e-141 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDGFOPHL_00149 3.5e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HDGFOPHL_00150 1.9e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HDGFOPHL_00151 8.4e-85 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
HDGFOPHL_00152 4.8e-193 C Aldo keto reductase family protein
HDGFOPHL_00153 2.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
HDGFOPHL_00154 2.6e-151 xth 3.1.11.2 L exodeoxyribonuclease III
HDGFOPHL_00155 8.5e-165 murB 1.3.1.98 M Cell wall formation
HDGFOPHL_00156 0.0 yjcE P Sodium proton antiporter
HDGFOPHL_00157 1.2e-123 S Protein of unknown function (DUF1361)
HDGFOPHL_00158 4.5e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDGFOPHL_00159 4.3e-135 ybbR S YbbR-like protein
HDGFOPHL_00160 7.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDGFOPHL_00161 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDGFOPHL_00162 1.7e-12
HDGFOPHL_00163 5e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDGFOPHL_00164 6e-250 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDGFOPHL_00165 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HDGFOPHL_00166 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HDGFOPHL_00167 1.2e-92 dps P Belongs to the Dps family
HDGFOPHL_00168 1.5e-25 copZ P Heavy-metal-associated domain
HDGFOPHL_00169 2.8e-199 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDGFOPHL_00170 1.8e-50
HDGFOPHL_00171 1.6e-81 S Iron Transport-associated domain
HDGFOPHL_00172 7.6e-174 M Iron Transport-associated domain
HDGFOPHL_00173 4.4e-90 M Iron Transport-associated domain
HDGFOPHL_00174 1.7e-162 isdE P Periplasmic binding protein
HDGFOPHL_00175 9.9e-172 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDGFOPHL_00176 2.7e-140 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
HDGFOPHL_00177 2e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HDGFOPHL_00178 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HDGFOPHL_00179 8.3e-290 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HDGFOPHL_00180 1.6e-151 licD M LicD family
HDGFOPHL_00181 1.9e-74 S Domain of unknown function (DUF5067)
HDGFOPHL_00182 3.7e-73 K Transcriptional regulator
HDGFOPHL_00183 1.9e-25
HDGFOPHL_00184 6e-79 O OsmC-like protein
HDGFOPHL_00185 3.2e-23
HDGFOPHL_00187 2e-56 ypaA S Protein of unknown function (DUF1304)
HDGFOPHL_00188 1.5e-86
HDGFOPHL_00189 3.6e-252 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDGFOPHL_00190 9.3e-46 sigM K Sigma-70 region 2
HDGFOPHL_00191 3.8e-72 S Sigma factor regulator C-terminal
HDGFOPHL_00192 1.1e-202 E Bacterial extracellular solute-binding proteins, family 5 Middle
HDGFOPHL_00193 2.8e-249 dapE 3.5.1.18 E Peptidase dimerisation domain
HDGFOPHL_00194 5.3e-209 G MFS/sugar transport protein
HDGFOPHL_00195 2.5e-119 K AraC family transcriptional regulator
HDGFOPHL_00196 0.0 rafA 3.2.1.22 G Melibiase
HDGFOPHL_00197 4.7e-106
HDGFOPHL_00198 3.5e-16
HDGFOPHL_00201 9e-147 K response regulator
HDGFOPHL_00202 2.1e-266 T PhoQ Sensor
HDGFOPHL_00203 1.4e-209 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
HDGFOPHL_00204 8.3e-154 glcU U sugar transport
HDGFOPHL_00205 7.1e-261 pgi 5.3.1.9 G Belongs to the GPI family
HDGFOPHL_00206 0.0 S Bacterial membrane protein YfhO
HDGFOPHL_00207 2.2e-79 tspO T TspO/MBR family
HDGFOPHL_00210 8.7e-160 S NAD:arginine ADP-ribosyltransferase
HDGFOPHL_00211 1e-196 ybiR P Citrate transporter
HDGFOPHL_00212 2.1e-120 yliE T Putative diguanylate phosphodiesterase
HDGFOPHL_00213 8.3e-146 2.7.7.65 T diguanylate cyclase
HDGFOPHL_00214 1.1e-08
HDGFOPHL_00215 8.9e-56
HDGFOPHL_00216 0.0 lmrA V ABC transporter, ATP-binding protein
HDGFOPHL_00217 0.0 yfiC V ABC transporter
HDGFOPHL_00218 3.3e-194 ampC V Beta-lactamase
HDGFOPHL_00219 4.3e-132 cobQ S glutamine amidotransferase
HDGFOPHL_00220 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HDGFOPHL_00221 8.5e-110 tdk 2.7.1.21 F thymidine kinase
HDGFOPHL_00222 3.5e-186 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDGFOPHL_00223 1.5e-152 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDGFOPHL_00224 7.9e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDGFOPHL_00225 5.6e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDGFOPHL_00226 1.5e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDGFOPHL_00227 6.1e-126 atpB C it plays a direct role in the translocation of protons across the membrane
HDGFOPHL_00228 7.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDGFOPHL_00229 3.4e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDGFOPHL_00230 2.6e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDGFOPHL_00231 1.6e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDGFOPHL_00232 7.3e-161 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDGFOPHL_00233 5.3e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDGFOPHL_00234 1.1e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HDGFOPHL_00235 1.3e-32 ywzB S Protein of unknown function (DUF1146)
HDGFOPHL_00236 4.8e-185 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDGFOPHL_00237 1e-44 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDGFOPHL_00238 6e-180 mbl D Cell shape determining protein MreB Mrl
HDGFOPHL_00239 5.4e-52 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HDGFOPHL_00240 1.1e-33 S Protein of unknown function (DUF2969)
HDGFOPHL_00241 1.1e-220 rodA D Belongs to the SEDS family
HDGFOPHL_00242 1.9e-49 gcsH2 E glycine cleavage
HDGFOPHL_00243 1.3e-140 f42a O Band 7 protein
HDGFOPHL_00244 3.9e-176 S Protein of unknown function (DUF2785)
HDGFOPHL_00245 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDGFOPHL_00246 2.9e-290 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HDGFOPHL_00247 2.2e-157 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HDGFOPHL_00248 1e-81 usp6 T universal stress protein
HDGFOPHL_00249 3.2e-41
HDGFOPHL_00250 2.2e-235 rarA L recombination factor protein RarA
HDGFOPHL_00251 7.1e-80 yueI S Protein of unknown function (DUF1694)
HDGFOPHL_00252 1.2e-111 yktB S Belongs to the UPF0637 family
HDGFOPHL_00253 9.3e-61 KLT serine threonine protein kinase
HDGFOPHL_00254 4.8e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDGFOPHL_00255 2.4e-83 ytsP 1.8.4.14 T GAF domain-containing protein
HDGFOPHL_00256 2.4e-311 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDGFOPHL_00257 1.1e-214 iscS2 2.8.1.7 E Aminotransferase class V
HDGFOPHL_00258 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDGFOPHL_00259 1e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDGFOPHL_00260 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDGFOPHL_00261 5.2e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDGFOPHL_00262 5.6e-118 radC L DNA repair protein
HDGFOPHL_00263 9.6e-162 mreB D cell shape determining protein MreB
HDGFOPHL_00264 9.7e-139 mreC M Involved in formation and maintenance of cell shape
HDGFOPHL_00265 3.2e-92 mreD M rod shape-determining protein MreD
HDGFOPHL_00266 1.8e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HDGFOPHL_00267 4.1e-147 minD D Belongs to the ParA family
HDGFOPHL_00268 2.5e-110 glnP P ABC transporter permease
HDGFOPHL_00269 4.2e-94 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDGFOPHL_00270 9.2e-158 aatB ET ABC transporter substrate-binding protein
HDGFOPHL_00271 5.5e-234 ymfF S Peptidase M16 inactive domain protein
HDGFOPHL_00272 3.4e-244 ymfH S Peptidase M16
HDGFOPHL_00273 6.4e-64 ymfM S Domain of unknown function (DUF4115)
HDGFOPHL_00274 2.3e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDGFOPHL_00275 1.1e-226 cinA 3.5.1.42 S Belongs to the CinA family
HDGFOPHL_00276 4e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDGFOPHL_00278 8.9e-223 rny S Endoribonuclease that initiates mRNA decay
HDGFOPHL_00279 5.1e-150 ymdB S YmdB-like protein
HDGFOPHL_00280 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDGFOPHL_00281 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDGFOPHL_00282 2.8e-108 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDGFOPHL_00283 1.2e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDGFOPHL_00284 4.1e-200 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDGFOPHL_00285 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDGFOPHL_00286 1.1e-26 yajC U Preprotein translocase
HDGFOPHL_00287 3.5e-181 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDGFOPHL_00288 2.2e-179 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HDGFOPHL_00289 1.4e-251 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDGFOPHL_00290 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDGFOPHL_00291 1.9e-43 yrzL S Belongs to the UPF0297 family
HDGFOPHL_00292 1.5e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDGFOPHL_00293 1.6e-51 yrzB S Belongs to the UPF0473 family
HDGFOPHL_00294 3.6e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDGFOPHL_00295 6.4e-88 cvpA S Colicin V production protein
HDGFOPHL_00296 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDGFOPHL_00297 2.7e-54 trxA O Belongs to the thioredoxin family
HDGFOPHL_00298 7.2e-92 yslB S Protein of unknown function (DUF2507)
HDGFOPHL_00299 2.7e-141 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDGFOPHL_00300 1.4e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDGFOPHL_00301 1.9e-100 S Phosphoesterase
HDGFOPHL_00302 4.6e-85 ykuL S (CBS) domain
HDGFOPHL_00304 1.8e-47 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDGFOPHL_00305 5.2e-243 U Major Facilitator Superfamily
HDGFOPHL_00306 4.1e-156 ykuT M mechanosensitive ion channel
HDGFOPHL_00307 6.9e-34 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDGFOPHL_00308 1.6e-42
HDGFOPHL_00309 2.7e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HDGFOPHL_00310 4.6e-180 ccpA K catabolite control protein A
HDGFOPHL_00311 3.7e-127
HDGFOPHL_00312 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDGFOPHL_00313 6.2e-266 glnPH2 P ABC transporter permease
HDGFOPHL_00314 2.6e-132 yebC K Transcriptional regulatory protein
HDGFOPHL_00315 2.9e-171 comGA NU Type II IV secretion system protein
HDGFOPHL_00316 1.4e-76 comGB NU type II secretion system
HDGFOPHL_00317 1.7e-38 comGB NU type II secretion system
HDGFOPHL_00318 2.4e-47 comGC U competence protein ComGC
HDGFOPHL_00319 2e-79
HDGFOPHL_00321 1.1e-74
HDGFOPHL_00322 7.4e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HDGFOPHL_00323 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDGFOPHL_00324 6.1e-255 cycA E Amino acid permease
HDGFOPHL_00325 1.5e-155 yeaE S Aldo keto
HDGFOPHL_00326 5.3e-115 S Calcineurin-like phosphoesterase
HDGFOPHL_00327 5.6e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDGFOPHL_00328 2.2e-85 yutD S Protein of unknown function (DUF1027)
HDGFOPHL_00329 1.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDGFOPHL_00330 4.2e-115 S Protein of unknown function (DUF1461)
HDGFOPHL_00331 5.9e-88 S WxL domain surface cell wall-binding
HDGFOPHL_00332 1.5e-268 XK27_00720 S Leucine-rich repeat (LRR) protein
HDGFOPHL_00333 2.1e-231 M domain protein
HDGFOPHL_00334 1.2e-250 yfnA E Amino Acid
HDGFOPHL_00335 7.4e-141 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HDGFOPHL_00336 4.5e-112 ytbE C Aldo keto reductase
HDGFOPHL_00337 1.3e-63 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDGFOPHL_00338 3.4e-13 K helix_turn_helix, mercury resistance
HDGFOPHL_00339 2.9e-122 dedA S SNARE-like domain protein
HDGFOPHL_00340 6.1e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HDGFOPHL_00341 2.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDGFOPHL_00342 5.2e-71 yugI 5.3.1.9 J general stress protein
HDGFOPHL_00343 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDGFOPHL_00344 4.3e-36 ykuJ S Protein of unknown function (DUF1797)
HDGFOPHL_00345 2.4e-184 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDGFOPHL_00346 1e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
HDGFOPHL_00347 6.1e-224 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HDGFOPHL_00348 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDGFOPHL_00349 7.2e-40 ptsH G phosphocarrier protein HPR
HDGFOPHL_00350 4.5e-30
HDGFOPHL_00351 0.0 clpE O Belongs to the ClpA ClpB family
HDGFOPHL_00352 2.9e-204 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HDGFOPHL_00353 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HDGFOPHL_00354 8.6e-281 pipD E Dipeptidase
HDGFOPHL_00355 3.7e-257 nox 1.6.3.4 C NADH oxidase
HDGFOPHL_00356 2.8e-272 XK27_00720 S Leucine-rich repeat (LRR) protein
HDGFOPHL_00357 6.5e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDGFOPHL_00358 5e-88
HDGFOPHL_00359 0.0 2.7.8.12 M glycerophosphotransferase
HDGFOPHL_00360 1e-151
HDGFOPHL_00361 2.6e-76 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HDGFOPHL_00362 2.6e-179 yueF S AI-2E family transporter
HDGFOPHL_00363 4.4e-108 ygaC J Belongs to the UPF0374 family
HDGFOPHL_00364 5.6e-39 S Bacteriocin-protection, YdeI or OmpD-Associated
HDGFOPHL_00365 3e-215 pbpX2 V Beta-lactamase
HDGFOPHL_00366 1.1e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
HDGFOPHL_00367 1e-78 fld C Flavodoxin
HDGFOPHL_00368 9e-159 yihY S Belongs to the UPF0761 family
HDGFOPHL_00369 1.8e-156 S Nuclease-related domain
HDGFOPHL_00370 5.9e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDGFOPHL_00371 3.2e-159 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
HDGFOPHL_00372 4.1e-232 gntP EG Gluconate
HDGFOPHL_00373 1.6e-76 T Universal stress protein family
HDGFOPHL_00375 3.6e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
HDGFOPHL_00376 1.5e-186 mocA S Oxidoreductase
HDGFOPHL_00377 5.7e-64 S Domain of unknown function (DUF4828)
HDGFOPHL_00378 1.1e-138 lys M Glycosyl hydrolases family 25
HDGFOPHL_00379 4.4e-147 gntR K rpiR family
HDGFOPHL_00380 1.2e-301 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
HDGFOPHL_00381 3.7e-209 gntP EG Gluconate
HDGFOPHL_00382 3.6e-233 potE E amino acid
HDGFOPHL_00383 5.3e-248 fucP G Major Facilitator Superfamily
HDGFOPHL_00384 2.5e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HDGFOPHL_00385 4.9e-293 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HDGFOPHL_00386 1.3e-238 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HDGFOPHL_00387 1.2e-172 deoR K sugar-binding domain protein
HDGFOPHL_00388 1.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HDGFOPHL_00389 3.8e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HDGFOPHL_00390 1.3e-120 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDGFOPHL_00391 5.1e-37 cro K Helix-turn-helix XRE-family like proteins
HDGFOPHL_00392 1e-57 K Helix-turn-helix XRE-family like proteins
HDGFOPHL_00393 1.7e-142 3.1.3.48 T Pfam:Y_phosphatase3C
HDGFOPHL_00394 2.5e-192 C Oxidoreductase
HDGFOPHL_00395 1.7e-54 pduU E BMC
HDGFOPHL_00396 1.6e-219 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDGFOPHL_00397 1.8e-209 pduQ C Iron-containing alcohol dehydrogenase
HDGFOPHL_00398 3e-265 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HDGFOPHL_00399 5.2e-81 pduO S Haem-degrading
HDGFOPHL_00400 7.6e-103 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HDGFOPHL_00401 3e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HDGFOPHL_00402 3e-90 S Putative propanediol utilisation
HDGFOPHL_00403 6.1e-114 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HDGFOPHL_00404 4.9e-42 pduA_4 CQ BMC
HDGFOPHL_00405 1.7e-79 pduK CQ BMC
HDGFOPHL_00406 1.3e-57 pduH S Dehydratase medium subunit
HDGFOPHL_00407 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
HDGFOPHL_00408 3e-90 pduE 4.2.1.28 Q Dehydratase small subunit
HDGFOPHL_00409 1e-128 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HDGFOPHL_00410 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HDGFOPHL_00411 1.2e-129 pduB E BMC
HDGFOPHL_00412 5.2e-41 pduA_4 CQ BMC
HDGFOPHL_00413 5.8e-205 K helix_turn_helix, arabinose operon control protein
HDGFOPHL_00414 9.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDGFOPHL_00415 1.9e-42 eutP E Ethanolamine utilisation - propanediol utilisation
HDGFOPHL_00416 9.1e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDGFOPHL_00417 1.3e-185 yegS 2.7.1.107 G Lipid kinase
HDGFOPHL_00418 6.5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDGFOPHL_00419 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDGFOPHL_00420 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDGFOPHL_00421 5.4e-193 camS S sex pheromone
HDGFOPHL_00422 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDGFOPHL_00423 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HDGFOPHL_00424 2.5e-214 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDGFOPHL_00425 5.1e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDGFOPHL_00426 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HDGFOPHL_00427 4.2e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDGFOPHL_00428 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HDGFOPHL_00429 5.3e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HDGFOPHL_00430 1.1e-173 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HDGFOPHL_00431 9.3e-283 cydA 1.10.3.14 C ubiquinol oxidase
HDGFOPHL_00432 3.3e-180 pdxB EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HDGFOPHL_00433 3.1e-144 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDGFOPHL_00434 4e-158 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDGFOPHL_00435 2.5e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HDGFOPHL_00436 8.8e-254 yfnA E Amino Acid
HDGFOPHL_00437 1.9e-194 asnA 6.3.1.1 F aspartate--ammonia ligase
HDGFOPHL_00438 1.5e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HDGFOPHL_00439 8.4e-221 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HDGFOPHL_00440 4.2e-104 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HDGFOPHL_00441 3.7e-196 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HDGFOPHL_00442 1.8e-116 ktrA P domain protein
HDGFOPHL_00443 1.4e-240 ktrB P Potassium uptake protein
HDGFOPHL_00444 1.6e-193 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDGFOPHL_00445 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HDGFOPHL_00446 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDGFOPHL_00447 4.2e-152 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDGFOPHL_00448 3e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDGFOPHL_00449 1.2e-160 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDGFOPHL_00450 2.9e-151 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDGFOPHL_00451 7.4e-62 rplQ J Ribosomal protein L17
HDGFOPHL_00452 9.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDGFOPHL_00453 7.5e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDGFOPHL_00454 1.3e-60 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDGFOPHL_00455 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDGFOPHL_00456 3.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDGFOPHL_00457 1.2e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDGFOPHL_00458 1.9e-69 rplO J Binds to the 23S rRNA
HDGFOPHL_00459 3.8e-24 rpmD J Ribosomal protein L30
HDGFOPHL_00460 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDGFOPHL_00461 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDGFOPHL_00462 3.9e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDGFOPHL_00463 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDGFOPHL_00464 2.1e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDGFOPHL_00465 1.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDGFOPHL_00466 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDGFOPHL_00467 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDGFOPHL_00468 4.8e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HDGFOPHL_00469 7.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDGFOPHL_00470 5.1e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDGFOPHL_00471 2.4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDGFOPHL_00472 1.8e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDGFOPHL_00473 6e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDGFOPHL_00474 2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDGFOPHL_00475 3.2e-107 rplD J Forms part of the polypeptide exit tunnel
HDGFOPHL_00476 6.1e-117 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDGFOPHL_00477 8.9e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
HDGFOPHL_00478 1.2e-231 mepA V MATE efflux family protein
HDGFOPHL_00479 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDGFOPHL_00480 3.2e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDGFOPHL_00481 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDGFOPHL_00482 5.9e-112 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HDGFOPHL_00483 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDGFOPHL_00484 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDGFOPHL_00485 4.7e-103 K Bacterial regulatory proteins, tetR family
HDGFOPHL_00486 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDGFOPHL_00487 9.9e-77 ctsR K Belongs to the CtsR family
HDGFOPHL_00496 2e-212 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDGFOPHL_00497 9.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HDGFOPHL_00498 1.8e-276 lysP E amino acid
HDGFOPHL_00499 1.4e-24 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDGFOPHL_00500 2.6e-130 I alpha/beta hydrolase fold
HDGFOPHL_00501 1e-119 lssY 3.6.1.27 I phosphatase
HDGFOPHL_00502 1.2e-71 S Threonine/Serine exporter, ThrE
HDGFOPHL_00503 3.1e-120 thrE S Putative threonine/serine exporter
HDGFOPHL_00504 5.3e-121 sirR K iron dependent repressor
HDGFOPHL_00505 4.4e-158 czcD P cation diffusion facilitator family transporter
HDGFOPHL_00506 4.3e-103 K Acetyltransferase (GNAT) domain
HDGFOPHL_00507 9.3e-77 merR K MerR HTH family regulatory protein
HDGFOPHL_00508 3.9e-268 lmrB EGP Major facilitator Superfamily
HDGFOPHL_00509 6.2e-102 S Domain of unknown function (DUF4811)
HDGFOPHL_00510 1e-37 yyaN K MerR HTH family regulatory protein
HDGFOPHL_00511 3.7e-107 azlC E branched-chain amino acid
HDGFOPHL_00512 1.4e-48 azlD S Branched-chain amino acid transport protein (AzlD)
HDGFOPHL_00513 2.3e-232 pyrP F Permease
HDGFOPHL_00514 8.1e-216 EGP Major facilitator Superfamily
HDGFOPHL_00515 1e-69
HDGFOPHL_00516 9.6e-89 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HDGFOPHL_00517 2.4e-104 3.2.2.20 K acetyltransferase
HDGFOPHL_00518 4e-139 yejC S Protein of unknown function (DUF1003)
HDGFOPHL_00519 1.3e-165 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HDGFOPHL_00520 2e-49 S Glycine cleavage H-protein
HDGFOPHL_00523 1.7e-86 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HDGFOPHL_00524 1e-278 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HDGFOPHL_00525 9.2e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HDGFOPHL_00526 1.5e-305 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
HDGFOPHL_00527 1.7e-249 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HDGFOPHL_00528 2.5e-195 araR K Transcriptional regulator
HDGFOPHL_00529 4.1e-88 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HDGFOPHL_00530 4e-167 K transcriptional regulator, ArsR family
HDGFOPHL_00531 4.6e-201 abf G Belongs to the glycosyl hydrolase 43 family
HDGFOPHL_00532 6.9e-237 lacY G Oligosaccharide H symporter
HDGFOPHL_00533 8.9e-297 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HDGFOPHL_00534 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HDGFOPHL_00535 9e-69 K Transcriptional regulator
HDGFOPHL_00536 1e-91 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HDGFOPHL_00537 1.5e-277 pipD E Dipeptidase
HDGFOPHL_00538 3.1e-263 arcD E Arginine ornithine antiporter
HDGFOPHL_00539 0.0 pepN 3.4.11.2 E aminopeptidase
HDGFOPHL_00540 2.8e-72 S Iron-sulphur cluster biosynthesis
HDGFOPHL_00541 0.0 rafA 3.2.1.22 G alpha-galactosidase
HDGFOPHL_00542 1.5e-58 bipA 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Leucine-rich repeat (LRR) protein
HDGFOPHL_00543 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HDGFOPHL_00544 2.3e-99 aacA4_1 4.1.1.17 K acetyltransferase
HDGFOPHL_00545 7e-175 coaA 2.7.1.33 F Pantothenic acid kinase
HDGFOPHL_00546 0.0 helD 3.6.4.12 L DNA helicase
HDGFOPHL_00547 3.4e-290 yjbQ P TrkA C-terminal domain protein
HDGFOPHL_00548 3.8e-119 G phosphoglycerate mutase
HDGFOPHL_00549 4.4e-180 oppF P Belongs to the ABC transporter superfamily
HDGFOPHL_00550 1.3e-204 oppD P Belongs to the ABC transporter superfamily
HDGFOPHL_00551 7.5e-186 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDGFOPHL_00552 2.2e-152 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDGFOPHL_00553 3.1e-295 oppA E ABC transporter, substratebinding protein
HDGFOPHL_00554 9.1e-303 oppA E ABC transporter, substratebinding protein
HDGFOPHL_00555 1.3e-224 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDGFOPHL_00556 1.1e-108 glnP P ABC transporter permease
HDGFOPHL_00557 1.1e-110 gluC P ABC transporter permease
HDGFOPHL_00558 2.4e-150 glnH ET ABC transporter substrate-binding protein
HDGFOPHL_00559 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDGFOPHL_00560 7.3e-172
HDGFOPHL_00561 5.3e-13 3.2.1.14 GH18
HDGFOPHL_00562 4.7e-79 zur P Belongs to the Fur family
HDGFOPHL_00563 2.3e-75 gmk2 2.7.4.8 F Guanylate kinase
HDGFOPHL_00564 7.1e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HDGFOPHL_00565 1.3e-241 yfnA E Amino Acid
HDGFOPHL_00566 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDGFOPHL_00567 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HDGFOPHL_00569 4.6e-87 M ErfK YbiS YcfS YnhG
HDGFOPHL_00570 6.7e-295 S ABC transporter, ATP-binding protein
HDGFOPHL_00571 2e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDGFOPHL_00572 1.2e-126 XK27_07075 S CAAX protease self-immunity
HDGFOPHL_00574 1.6e-11 M domain protein
HDGFOPHL_00575 1.8e-119 cmpC S ATPases associated with a variety of cellular activities
HDGFOPHL_00576 1.7e-168 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HDGFOPHL_00577 2.4e-165 XK27_00670 S ABC transporter
HDGFOPHL_00578 7.2e-161 degV S Uncharacterised protein, DegV family COG1307
HDGFOPHL_00579 2.9e-179 XK27_08835 S ABC transporter
HDGFOPHL_00580 3e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HDGFOPHL_00581 1.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
HDGFOPHL_00583 6.2e-157 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HDGFOPHL_00584 1.5e-127 terC P integral membrane protein, YkoY family
HDGFOPHL_00585 2.9e-243 pbpX1 V SH3-like domain
HDGFOPHL_00586 1.5e-109 NU mannosyl-glycoprotein
HDGFOPHL_00587 1.1e-181 S DUF218 domain
HDGFOPHL_00588 1.4e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDGFOPHL_00589 4.5e-135 IQ reductase
HDGFOPHL_00590 3.2e-15
HDGFOPHL_00591 0.0 ydgH S MMPL family
HDGFOPHL_00592 7.3e-256 ydiC1 EGP Major facilitator Superfamily
HDGFOPHL_00593 1.4e-90 K Transcriptional regulator PadR-like family
HDGFOPHL_00594 2.7e-82 merR K MerR family regulatory protein
HDGFOPHL_00595 1.5e-61 iap CBM50 M NlpC P60 family
HDGFOPHL_00596 5.4e-77 yjcF K protein acetylation
HDGFOPHL_00597 5.8e-123 pgm3 G phosphoglycerate mutase family
HDGFOPHL_00598 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDGFOPHL_00599 2.9e-182 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HDGFOPHL_00600 5.2e-144 S Alpha/beta hydrolase of unknown function (DUF915)
HDGFOPHL_00601 2.7e-191 S Protease prsW family
HDGFOPHL_00602 7e-178 iunH2 3.2.2.1, 3.2.2.8 F nucleoside hydrolase
HDGFOPHL_00603 1.6e-07 yvlA
HDGFOPHL_00604 9.7e-86
HDGFOPHL_00605 6.9e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HDGFOPHL_00606 3.3e-152 S Alpha/beta hydrolase of unknown function (DUF915)
HDGFOPHL_00607 2.4e-234 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGFOPHL_00608 6.8e-73 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HDGFOPHL_00609 8.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
HDGFOPHL_00610 8.9e-56 S LuxR family transcriptional regulator
HDGFOPHL_00611 4.8e-125 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HDGFOPHL_00612 7.7e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDGFOPHL_00613 5.7e-169 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDGFOPHL_00614 9.7e-95 S ABC transporter permease
HDGFOPHL_00615 1.6e-255 P ABC transporter
HDGFOPHL_00616 7.5e-115 P Cobalt transport protein
HDGFOPHL_00617 2.7e-120 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HDGFOPHL_00618 6.6e-60
HDGFOPHL_00619 1.1e-08
HDGFOPHL_00621 2.3e-30
HDGFOPHL_00622 6e-216
HDGFOPHL_00623 1.5e-186 ansA 3.5.1.1 EJ Asparaginase
HDGFOPHL_00624 3.2e-24
HDGFOPHL_00625 4.7e-247 pbuX F xanthine permease
HDGFOPHL_00626 7.2e-169 natA S ABC transporter, ATP-binding protein
HDGFOPHL_00627 1.2e-211 natB CP ABC-2 family transporter protein
HDGFOPHL_00629 5.7e-250 yjjP S Putative threonine/serine exporter
HDGFOPHL_00630 1.7e-151 degV S Uncharacterised protein, DegV family COG1307
HDGFOPHL_00631 1.3e-153 1.1.1.2, 1.1.1.307 C Aldo keto reductase
HDGFOPHL_00632 3.4e-64 S Protein of unknown function (DUF1722)
HDGFOPHL_00633 1.7e-68 yqeB S Pyrimidine dimer DNA glycosylase
HDGFOPHL_00634 5.8e-282 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HDGFOPHL_00635 1.7e-125 K Crp-like helix-turn-helix domain
HDGFOPHL_00636 2.1e-238 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HDGFOPHL_00637 2.1e-132 cpmA S AIR carboxylase
HDGFOPHL_00638 2.1e-227 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HDGFOPHL_00639 1.6e-149 larE S NAD synthase
HDGFOPHL_00640 2.2e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDGFOPHL_00641 1.4e-178 hoxN U High-affinity nickel-transport protein
HDGFOPHL_00642 2.6e-103 aroD S Serine hydrolase (FSH1)
HDGFOPHL_00643 4.2e-42 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
HDGFOPHL_00646 3.1e-209 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDGFOPHL_00647 3.8e-148 potB P ABC transporter permease
HDGFOPHL_00648 4.4e-133 potC P ABC transporter permease
HDGFOPHL_00649 9.2e-203 potD P ABC transporter
HDGFOPHL_00650 1.8e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDGFOPHL_00651 4.7e-144 pstA P Phosphate transport system permease protein PstA
HDGFOPHL_00652 2.9e-168 pstC P probably responsible for the translocation of the substrate across the membrane
HDGFOPHL_00653 1.2e-152 pstS P Phosphate
HDGFOPHL_00654 1.7e-57
HDGFOPHL_00655 8e-31
HDGFOPHL_00656 1.8e-43
HDGFOPHL_00657 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HDGFOPHL_00658 1.2e-123
HDGFOPHL_00659 2.8e-176 sepS16B
HDGFOPHL_00660 1.1e-284 V ABC transporter transmembrane region
HDGFOPHL_00661 0.0 KLT Protein kinase domain
HDGFOPHL_00663 0.0 yhcA V ABC transporter, ATP-binding protein
HDGFOPHL_00664 4.7e-100 bm3R1 K Psort location Cytoplasmic, score
HDGFOPHL_00665 4.3e-65 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDGFOPHL_00666 6.4e-38 S Mor transcription activator family
HDGFOPHL_00667 1.1e-40 S Mor transcription activator family
HDGFOPHL_00668 2.1e-19 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HDGFOPHL_00669 4e-19 S Mor transcription activator family
HDGFOPHL_00670 1.3e-123 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HDGFOPHL_00671 4.4e-190 ybhR V ABC transporter
HDGFOPHL_00672 1.6e-114 K Bacterial regulatory proteins, tetR family
HDGFOPHL_00673 4e-177 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HDGFOPHL_00674 8.6e-57 yqkB S Belongs to the HesB IscA family
HDGFOPHL_00675 9.6e-198 yjcE P Sodium proton antiporter
HDGFOPHL_00676 1.8e-23 yeaN P Major Facilitator Superfamily
HDGFOPHL_00677 0.0 kup P Transport of potassium into the cell
HDGFOPHL_00678 2e-180 C Zinc-binding dehydrogenase
HDGFOPHL_00679 1.1e-99 1.1.1.219 GM Male sterility protein
HDGFOPHL_00680 1.4e-72 K helix_turn_helix, mercury resistance
HDGFOPHL_00681 3.8e-32 P ATPases associated with a variety of cellular activities
HDGFOPHL_00683 1e-198 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HDGFOPHL_00684 2.2e-77 K Transcriptional regulator
HDGFOPHL_00685 9.3e-161 akr5f 1.1.1.346 S reductase
HDGFOPHL_00686 5.7e-163 S Oxidoreductase, aldo keto reductase family protein
HDGFOPHL_00687 1.5e-80
HDGFOPHL_00688 8.7e-215 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HDGFOPHL_00689 3e-153 yitU 3.1.3.104 S hydrolase
HDGFOPHL_00690 7.9e-268 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HDGFOPHL_00691 7.3e-189 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDGFOPHL_00692 2.4e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HDGFOPHL_00693 6.2e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HDGFOPHL_00694 1e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HDGFOPHL_00695 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HDGFOPHL_00696 2.6e-83 ypmB S Protein conserved in bacteria
HDGFOPHL_00697 8e-208 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HDGFOPHL_00698 2.7e-123 dnaD L Replication initiation and membrane attachment
HDGFOPHL_00699 1.5e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
HDGFOPHL_00700 2.2e-60 P Rhodanese Homology Domain
HDGFOPHL_00701 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HDGFOPHL_00702 5.2e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDGFOPHL_00703 1.6e-105 ypsA S Belongs to the UPF0398 family
HDGFOPHL_00704 6.4e-28 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDGFOPHL_00706 6.1e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HDGFOPHL_00707 2.9e-66 FG Scavenger mRNA decapping enzyme C-term binding
HDGFOPHL_00708 1.3e-243 amtB P ammonium transporter
HDGFOPHL_00709 4.8e-28
HDGFOPHL_00710 9.7e-84 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
HDGFOPHL_00711 2e-53
HDGFOPHL_00712 4.1e-124 S CAAX protease self-immunity
HDGFOPHL_00713 2.5e-84 K Bacterial regulatory proteins, tetR family
HDGFOPHL_00714 6.1e-111 XK27_02070 S Nitroreductase family
HDGFOPHL_00715 6.4e-207 yurR 1.4.5.1 E FAD dependent oxidoreductase
HDGFOPHL_00716 6.8e-66 rnhA 3.1.26.4 L Ribonuclease HI
HDGFOPHL_00717 2.4e-56 esbA S Family of unknown function (DUF5322)
HDGFOPHL_00718 2.8e-307 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HDGFOPHL_00719 5.7e-81 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDGFOPHL_00720 5.5e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDGFOPHL_00721 6.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDGFOPHL_00722 1.5e-205 carA 6.3.5.5 F Belongs to the CarA family
HDGFOPHL_00723 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HDGFOPHL_00724 0.0 FbpA K Fibronectin-binding protein
HDGFOPHL_00725 6.3e-70 K Transcriptional regulator
HDGFOPHL_00726 1.1e-194 npp S type I phosphodiesterase nucleotide pyrophosphatase
HDGFOPHL_00727 5.4e-231 yxiO S Vacuole effluxer Atg22 like
HDGFOPHL_00728 7.8e-160 degV S EDD domain protein, DegV family
HDGFOPHL_00729 4.1e-87 folT S ECF transporter, substrate-specific component
HDGFOPHL_00730 8.7e-75 gtcA S Teichoic acid glycosylation protein
HDGFOPHL_00731 2.9e-82 ysaA V VanZ like family
HDGFOPHL_00732 2e-91 V VanZ like family
HDGFOPHL_00733 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDGFOPHL_00735 2.6e-17
HDGFOPHL_00736 1.5e-125 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HDGFOPHL_00737 3.1e-122 Q Methyltransferase domain
HDGFOPHL_00738 3.1e-118 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDGFOPHL_00739 1.3e-46 yneE K Transcriptional regulator
HDGFOPHL_00740 3.2e-50 yneE K Transcriptional regulator
HDGFOPHL_00741 7.3e-89 K Transcriptional regulator
HDGFOPHL_00742 3.8e-17 S membrane
HDGFOPHL_00743 1.3e-64 K Bacterial regulatory proteins, tetR family
HDGFOPHL_00744 3.6e-199 xerS L Belongs to the 'phage' integrase family
HDGFOPHL_00745 3.9e-75 3.6.1.55 F NUDIX domain
HDGFOPHL_00746 5.8e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDGFOPHL_00747 1.3e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HDGFOPHL_00748 6.2e-97 zmp1 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HDGFOPHL_00749 4.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
HDGFOPHL_00750 4.7e-182 K Transcriptional regulator
HDGFOPHL_00751 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDGFOPHL_00752 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDGFOPHL_00753 3.2e-99 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDGFOPHL_00754 2.7e-168 lacX 5.1.3.3 G Aldose 1-epimerase
HDGFOPHL_00755 1.8e-262 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDGFOPHL_00756 1.8e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDGFOPHL_00757 8.3e-176 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HDGFOPHL_00758 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDGFOPHL_00759 1.5e-166 dprA LU DNA protecting protein DprA
HDGFOPHL_00760 7.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDGFOPHL_00761 1.4e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDGFOPHL_00762 2.7e-66 abiGI K Psort location Cytoplasmic, score
HDGFOPHL_00763 8.2e-120
HDGFOPHL_00764 5.8e-35 yozE S Belongs to the UPF0346 family
HDGFOPHL_00765 2.1e-103 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HDGFOPHL_00766 2.7e-158 ypmR E GDSL-like Lipase/Acylhydrolase
HDGFOPHL_00767 1e-148 DegV S EDD domain protein, DegV family
HDGFOPHL_00768 2.8e-114 hlyIII S protein, hemolysin III
HDGFOPHL_00769 9.1e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDGFOPHL_00770 1.1e-186 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDGFOPHL_00771 0.0 yfmR S ABC transporter, ATP-binding protein
HDGFOPHL_00772 6.4e-221 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDGFOPHL_00773 2.1e-171 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDGFOPHL_00774 7.2e-231 S Tetratricopeptide repeat protein
HDGFOPHL_00775 1.5e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDGFOPHL_00776 5.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HDGFOPHL_00777 1.1e-210 rpsA 1.17.7.4 J Ribosomal protein S1
HDGFOPHL_00778 6.4e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HDGFOPHL_00779 1.2e-24 M Lysin motif
HDGFOPHL_00780 4.1e-251 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HDGFOPHL_00781 1.4e-179 ypbB 5.1.3.1 S Helix-turn-helix domain
HDGFOPHL_00782 5.7e-84 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDGFOPHL_00783 7.7e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDGFOPHL_00784 3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDGFOPHL_00785 1.1e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDGFOPHL_00786 3.1e-71 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDGFOPHL_00787 2.7e-163 xerD D recombinase XerD
HDGFOPHL_00788 1.8e-167 cvfB S S1 domain
HDGFOPHL_00789 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HDGFOPHL_00790 4.4e-124 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HDGFOPHL_00791 0.0 dnaE 2.7.7.7 L DNA polymerase
HDGFOPHL_00792 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDGFOPHL_00793 2.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDGFOPHL_00794 1.6e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDGFOPHL_00795 2.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
HDGFOPHL_00796 0.0 ydgH S MMPL family
HDGFOPHL_00797 3.6e-88 K Transcriptional regulator
HDGFOPHL_00798 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDGFOPHL_00799 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDGFOPHL_00800 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HDGFOPHL_00801 1.5e-177 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HDGFOPHL_00802 1.2e-148 recO L Involved in DNA repair and RecF pathway recombination
HDGFOPHL_00803 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDGFOPHL_00804 3.4e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HDGFOPHL_00805 8.5e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDGFOPHL_00806 1.2e-180 phoH T phosphate starvation-inducible protein PhoH
HDGFOPHL_00807 7e-72 yqeY S YqeY-like protein
HDGFOPHL_00808 9.9e-67 hxlR K Transcriptional regulator, HxlR family
HDGFOPHL_00809 5.7e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HDGFOPHL_00810 1.3e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HDGFOPHL_00811 3.1e-150 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDGFOPHL_00812 7.3e-172 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HDGFOPHL_00813 3e-242 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
HDGFOPHL_00814 8e-151 tagG U Transport permease protein
HDGFOPHL_00815 1.1e-188 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDGFOPHL_00816 1.9e-161 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDGFOPHL_00817 8.2e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDGFOPHL_00818 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDGFOPHL_00819 2.5e-247 hisS 6.1.1.21 J histidyl-tRNA synthetase
HDGFOPHL_00820 2.9e-93
HDGFOPHL_00821 2.2e-159 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HDGFOPHL_00822 1.1e-155 yniA G Fructosamine kinase
HDGFOPHL_00823 6.9e-113 3.1.3.18 S HAD-hyrolase-like
HDGFOPHL_00824 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDGFOPHL_00825 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDGFOPHL_00826 2.3e-59
HDGFOPHL_00827 1.7e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDGFOPHL_00828 9.7e-180 prmA J Ribosomal protein L11 methyltransferase
HDGFOPHL_00829 1.2e-54
HDGFOPHL_00830 9.1e-28 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDGFOPHL_00831 1.8e-62
HDGFOPHL_00833 2.1e-41
HDGFOPHL_00834 4.5e-09
HDGFOPHL_00835 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDGFOPHL_00836 3.2e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDGFOPHL_00837 5.2e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDGFOPHL_00838 3.8e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
HDGFOPHL_00839 8.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDGFOPHL_00840 6.3e-17 dltX S D-Ala-teichoic acid biosynthesis protein
HDGFOPHL_00841 4.9e-178 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDGFOPHL_00842 0.0 dnaK O Heat shock 70 kDa protein
HDGFOPHL_00843 5.2e-83 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDGFOPHL_00844 7.8e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDGFOPHL_00845 4.3e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HDGFOPHL_00846 1.6e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDGFOPHL_00847 9.4e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDGFOPHL_00848 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDGFOPHL_00849 1.4e-44 ylxQ J ribosomal protein
HDGFOPHL_00850 2.3e-47 ylxR K Protein of unknown function (DUF448)
HDGFOPHL_00851 2.6e-190 nusA K Participates in both transcription termination and antitermination
HDGFOPHL_00852 1.8e-81 rimP J Required for maturation of 30S ribosomal subunits
HDGFOPHL_00853 1.4e-38
HDGFOPHL_00854 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDGFOPHL_00855 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDGFOPHL_00856 7.8e-233 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HDGFOPHL_00857 1.1e-136 cdsA 2.7.7.41 I Belongs to the CDS family
HDGFOPHL_00858 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDGFOPHL_00859 3.2e-74
HDGFOPHL_00860 6.9e-85 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDGFOPHL_00861 1.7e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HDGFOPHL_00862 1.9e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDGFOPHL_00863 3.8e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HDGFOPHL_00864 7.2e-135 S Haloacid dehalogenase-like hydrolase
HDGFOPHL_00865 6.8e-184 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDGFOPHL_00866 6.4e-44 yazA L GIY-YIG catalytic domain protein
HDGFOPHL_00867 6.1e-137 yabB 2.1.1.223 L Methyltransferase small domain
HDGFOPHL_00868 1.5e-120 plsC 2.3.1.51 I Acyltransferase
HDGFOPHL_00869 0.0 mdlB V ABC transporter
HDGFOPHL_00870 2.2e-286 mdlA V ABC transporter
HDGFOPHL_00871 1.6e-32 yneF S Uncharacterised protein family (UPF0154)
HDGFOPHL_00872 1.8e-37 ynzC S UPF0291 protein
HDGFOPHL_00873 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDGFOPHL_00874 9.3e-77 F nucleoside 2-deoxyribosyltransferase
HDGFOPHL_00875 6e-79
HDGFOPHL_00876 3.2e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HDGFOPHL_00877 4.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HDGFOPHL_00878 5.3e-124 G phosphoglycerate mutase
HDGFOPHL_00879 7.7e-25 KT PspC domain
HDGFOPHL_00880 1e-81 ndk 2.7.4.6 F Belongs to the NDK family
HDGFOPHL_00883 7.7e-62
HDGFOPHL_00886 1.7e-69 S MTH538 TIR-like domain (DUF1863)
HDGFOPHL_00887 1.2e-160 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HDGFOPHL_00888 5.7e-73
HDGFOPHL_00890 3.3e-77 T Universal stress protein family
HDGFOPHL_00891 3.2e-92 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDGFOPHL_00892 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HDGFOPHL_00893 2.6e-54 yrvD S Pfam:DUF1049
HDGFOPHL_00894 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDGFOPHL_00895 5e-28
HDGFOPHL_00896 5.3e-104
HDGFOPHL_00897 3.3e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDGFOPHL_00898 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDGFOPHL_00899 1.1e-15
HDGFOPHL_00900 3.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HDGFOPHL_00901 6.6e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HDGFOPHL_00902 5e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDGFOPHL_00903 2.2e-222 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDGFOPHL_00904 1.9e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDGFOPHL_00905 2e-166 S Tetratricopeptide repeat
HDGFOPHL_00906 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDGFOPHL_00907 1.3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDGFOPHL_00908 2.1e-33 rpsT J Binds directly to 16S ribosomal RNA
HDGFOPHL_00909 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HDGFOPHL_00910 0.0 comEC S Competence protein ComEC
HDGFOPHL_00911 8.8e-89 comEB 3.5.4.12 F ComE operon protein 2
HDGFOPHL_00912 1.1e-119 comEA L Competence protein ComEA
HDGFOPHL_00913 2.8e-196 ylbL T Belongs to the peptidase S16 family
HDGFOPHL_00914 1.8e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDGFOPHL_00915 2.5e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HDGFOPHL_00916 4.4e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HDGFOPHL_00917 1.6e-208 ftsW D Belongs to the SEDS family
HDGFOPHL_00918 0.0 typA T GTP-binding protein TypA
HDGFOPHL_00919 1.8e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HDGFOPHL_00920 7.9e-45 yktA S Belongs to the UPF0223 family
HDGFOPHL_00921 1e-162 1.1.1.27 C L-malate dehydrogenase activity
HDGFOPHL_00922 2e-269 lpdA 1.8.1.4 C Dehydrogenase
HDGFOPHL_00923 2.1e-201 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDGFOPHL_00924 2.8e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HDGFOPHL_00925 7e-214 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HDGFOPHL_00926 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDGFOPHL_00927 2e-67
HDGFOPHL_00928 1.2e-32 ykzG S Belongs to the UPF0356 family
HDGFOPHL_00929 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDGFOPHL_00930 4.8e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HDGFOPHL_00931 1.3e-28
HDGFOPHL_00932 8.2e-115 mltD CBM50 M NlpC P60 family protein
HDGFOPHL_00933 3.1e-163 ypuA S Protein of unknown function (DUF1002)
HDGFOPHL_00934 4.2e-169 ykfC 3.4.14.13 M NlpC/P60 family
HDGFOPHL_00935 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDGFOPHL_00936 2.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDGFOPHL_00937 4e-184 rbsR K helix_turn _helix lactose operon repressor
HDGFOPHL_00938 7e-189 yghZ C Aldo keto reductase family protein
HDGFOPHL_00939 8.4e-157 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDGFOPHL_00940 2.5e-308 E ABC transporter, substratebinding protein
HDGFOPHL_00941 1.9e-275 nylA 3.5.1.4 J Belongs to the amidase family
HDGFOPHL_00942 1.9e-158 yckB ET Belongs to the bacterial solute-binding protein 3 family
HDGFOPHL_00943 2.5e-121 yecS E ABC transporter permease
HDGFOPHL_00944 1.2e-126 yoaK S Protein of unknown function (DUF1275)
HDGFOPHL_00945 6.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDGFOPHL_00946 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDGFOPHL_00947 6.8e-119 S Repeat protein
HDGFOPHL_00948 2.8e-117 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HDGFOPHL_00949 2.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDGFOPHL_00950 3.4e-58 XK27_04120 S Putative amino acid metabolism
HDGFOPHL_00951 4e-223 iscS 2.8.1.7 E Aminotransferase class V
HDGFOPHL_00952 2.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDGFOPHL_00953 3.4e-30
HDGFOPHL_00954 2.5e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HDGFOPHL_00955 2.2e-34 cspA K Cold shock protein
HDGFOPHL_00956 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDGFOPHL_00957 3.3e-92 divIVA D DivIVA domain protein
HDGFOPHL_00958 5.4e-144 ylmH S S4 domain protein
HDGFOPHL_00959 4.1e-41 yggT S YGGT family
HDGFOPHL_00960 6.5e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDGFOPHL_00961 1.1e-215 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDGFOPHL_00962 2e-244 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDGFOPHL_00963 1.4e-145 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDGFOPHL_00964 3.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDGFOPHL_00965 4.9e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDGFOPHL_00966 1.9e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDGFOPHL_00967 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HDGFOPHL_00968 1.7e-61 ftsL D Cell division protein FtsL
HDGFOPHL_00969 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDGFOPHL_00970 2e-79 mraZ K Belongs to the MraZ family
HDGFOPHL_00971 4.9e-60 S Protein of unknown function (DUF3397)
HDGFOPHL_00972 2.2e-12 S Protein of unknown function (DUF4044)
HDGFOPHL_00973 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HDGFOPHL_00974 2.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDGFOPHL_00975 4.2e-158 rrmA 2.1.1.187 H Methyltransferase
HDGFOPHL_00976 6e-203 XK27_05220 S AI-2E family transporter
HDGFOPHL_00977 1.5e-107 cutC P Participates in the control of copper homeostasis
HDGFOPHL_00980 4.8e-51
HDGFOPHL_00981 3.3e-189 6.3.1.20 H Lipoate-protein ligase
HDGFOPHL_00982 4.5e-64 gcvH E glycine cleavage
HDGFOPHL_00983 1.3e-182 tas C Aldo/keto reductase family
HDGFOPHL_00984 1e-31
HDGFOPHL_00985 2.1e-177 EG EamA-like transporter family
HDGFOPHL_00986 2.1e-112 metI P ABC transporter permease
HDGFOPHL_00987 2e-194 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDGFOPHL_00988 3.5e-146 P Belongs to the nlpA lipoprotein family
HDGFOPHL_00989 4.4e-100 tag 3.2.2.20 L glycosylase
HDGFOPHL_00990 0.0 E ABC transporter, substratebinding protein
HDGFOPHL_00992 0.0 3.2.1.21 GH3 G hydrolase, family 3
HDGFOPHL_00993 2.5e-191 pva1 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HDGFOPHL_00994 8.4e-305 sbcC L Putative exonuclease SbcCD, C subunit
HDGFOPHL_00995 4.3e-211 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDGFOPHL_00996 4.6e-105 tag 3.2.2.20 L glycosylase
HDGFOPHL_00997 3.1e-146 S Zinc-dependent metalloprotease
HDGFOPHL_00998 2.1e-166 XK27_00880 3.5.1.28 M hydrolase, family 25
HDGFOPHL_00999 1.2e-205 G Glycosyl hydrolases family 8
HDGFOPHL_01000 8.6e-56 yphJ 4.1.1.44 S decarboxylase
HDGFOPHL_01001 4.3e-79 yphH S Cupin domain
HDGFOPHL_01002 1.3e-75 K helix_turn_helix, mercury resistance
HDGFOPHL_01003 2e-100 yobS K Bacterial regulatory proteins, tetR family
HDGFOPHL_01004 2e-09 K MarR family
HDGFOPHL_01005 1.3e-224
HDGFOPHL_01006 1.7e-159 dkgB S reductase
HDGFOPHL_01007 8.6e-202 EGP Major facilitator Superfamily
HDGFOPHL_01008 1e-194 EGP Major facilitator Superfamily
HDGFOPHL_01009 4.1e-133 C Oxidoreductase
HDGFOPHL_01010 1.9e-40 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HDGFOPHL_01011 2.8e-59 K helix_turn_helix, arabinose operon control protein
HDGFOPHL_01012 1.5e-52 S Domain of unknown function (DUF4430)
HDGFOPHL_01013 3.8e-177 U FFAT motif binding
HDGFOPHL_01014 1.4e-113 S ECF-type riboflavin transporter, S component
HDGFOPHL_01015 7.8e-294 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
HDGFOPHL_01016 3.1e-156 P ABC-type cobalt transport system permease component CbiQ and related transporters
HDGFOPHL_01017 1.5e-68
HDGFOPHL_01018 2.6e-95 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HDGFOPHL_01019 2.3e-281 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HDGFOPHL_01020 5.1e-159 K LysR substrate binding domain
HDGFOPHL_01021 2.3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDGFOPHL_01022 2e-292 epsA I PAP2 superfamily
HDGFOPHL_01023 2.7e-109 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
HDGFOPHL_01024 1.2e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HDGFOPHL_01025 0.0 lmrA 3.6.3.44 V ABC transporter
HDGFOPHL_01026 1.1e-82 rmaB K Transcriptional regulator, MarR family
HDGFOPHL_01027 6.9e-114 S membrane transporter protein
HDGFOPHL_01028 2.4e-136 3.1.3.48 T Tyrosine phosphatase family
HDGFOPHL_01029 3.9e-123
HDGFOPHL_01030 1.1e-124 skfE V ATPases associated with a variety of cellular activities
HDGFOPHL_01031 3.2e-62 yvoA_1 K Transcriptional regulator, GntR family
HDGFOPHL_01032 3.6e-174 3.5.2.6 V Beta-lactamase enzyme family
HDGFOPHL_01033 1.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HDGFOPHL_01034 1.3e-126 S haloacid dehalogenase-like hydrolase
HDGFOPHL_01035 3.5e-203 bcr1 EGP Major facilitator Superfamily
HDGFOPHL_01036 6.6e-145 S Sucrose-6F-phosphate phosphohydrolase
HDGFOPHL_01037 5.2e-155 map 3.4.11.18 E Methionine Aminopeptidase
HDGFOPHL_01038 1.5e-92
HDGFOPHL_01040 2.2e-131 ydfG S KR domain
HDGFOPHL_01041 1.7e-63 hxlR K HxlR-like helix-turn-helix
HDGFOPHL_01042 7.4e-60 asp2 S Asp23 family, cell envelope-related function
HDGFOPHL_01043 3.6e-70 asp S Asp23 family, cell envelope-related function
HDGFOPHL_01044 5.9e-25
HDGFOPHL_01045 1.4e-90
HDGFOPHL_01046 7.8e-15 S Transglycosylase associated protein
HDGFOPHL_01047 3.2e-156
HDGFOPHL_01048 2.2e-269 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HDGFOPHL_01049 6.8e-183 chaT1 U Major Facilitator Superfamily
HDGFOPHL_01050 2.9e-94 laaE K Transcriptional regulator PadR-like family
HDGFOPHL_01051 1e-66 lysM M LysM domain
HDGFOPHL_01052 4.1e-130 XK27_07210 6.1.1.6 S B3 4 domain
HDGFOPHL_01053 3.3e-121 iprA K Cyclic nucleotide-monophosphate binding domain
HDGFOPHL_01054 1.8e-170 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HDGFOPHL_01055 2e-216 arcT 2.6.1.1 E Aminotransferase
HDGFOPHL_01056 5e-257 arcD E Arginine ornithine antiporter
HDGFOPHL_01057 3.3e-197 argF 2.1.3.3, 2.1.3.6, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDGFOPHL_01058 7.7e-238 arcA 3.5.3.6 E Arginine
HDGFOPHL_01059 5.7e-278 S C4-dicarboxylate anaerobic carrier
HDGFOPHL_01060 5.3e-221 2.1.1.80, 2.7.13.3, 3.1.1.61 T histidine kinase DNA gyrase B
HDGFOPHL_01061 6.5e-148 KT YcbB domain
HDGFOPHL_01062 1.2e-280 arcD S C4-dicarboxylate anaerobic carrier
HDGFOPHL_01063 3.5e-260 ytjP 3.5.1.18 E Dipeptidase
HDGFOPHL_01065 1.3e-207 ykiI
HDGFOPHL_01066 5.4e-46 thiJ-2 3.5.1.124 S DJ-1/PfpI family
HDGFOPHL_01067 1.1e-44 thiJ-2 3.5.1.124 S DJ-1/PfpI family
HDGFOPHL_01068 6.8e-191 yjcE P Sodium proton antiporter
HDGFOPHL_01069 1.9e-159 3.1.3.48 T Tyrosine phosphatase family
HDGFOPHL_01070 1.5e-221 EGP Major facilitator Superfamily
HDGFOPHL_01071 5.7e-68 yobT S PFAM Metallo-beta-lactamase superfamily
HDGFOPHL_01072 2.2e-16 K helix_turn_helix, mercury resistance
HDGFOPHL_01074 7.5e-34 S Protein of unknown function (DUF3781)
HDGFOPHL_01075 7.5e-39
HDGFOPHL_01076 1.5e-77 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
HDGFOPHL_01077 1.2e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDGFOPHL_01078 1.6e-256 M domain protein
HDGFOPHL_01079 2.3e-169 K AI-2E family transporter
HDGFOPHL_01080 1.3e-210 xylR GK ROK family
HDGFOPHL_01081 9.7e-121
HDGFOPHL_01082 7.7e-235 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HDGFOPHL_01083 1.3e-52 azlD S branched-chain amino acid
HDGFOPHL_01084 7.2e-136 azlC E AzlC protein
HDGFOPHL_01085 3e-87 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HDGFOPHL_01086 6.2e-249 gor 1.8.1.7 C Glutathione reductase
HDGFOPHL_01087 2.9e-33 S Domain of unknown function (DUF4430)
HDGFOPHL_01088 6.8e-174 V domain protein
HDGFOPHL_01089 1.2e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDGFOPHL_01090 4.9e-210 hpk31 2.7.13.3 T Histidine kinase
HDGFOPHL_01091 3.5e-123 K response regulator
HDGFOPHL_01092 3.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDGFOPHL_01093 1.7e-102
HDGFOPHL_01094 1.2e-132 XK27_01040 S Protein of unknown function (DUF1129)
HDGFOPHL_01095 2.2e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDGFOPHL_01096 3.2e-32 yyzM S Bacterial protein of unknown function (DUF951)
HDGFOPHL_01097 3.4e-155 spo0J K Belongs to the ParB family
HDGFOPHL_01098 4.1e-136 soj D Sporulation initiation inhibitor
HDGFOPHL_01099 1.7e-143 noc K Belongs to the ParB family
HDGFOPHL_01100 2.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HDGFOPHL_01101 2.5e-158 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HDGFOPHL_01102 2.8e-168 rihC 3.2.2.1, 3.2.2.8 F Nucleoside
HDGFOPHL_01103 9.8e-215 pbuO_1 S Permease family
HDGFOPHL_01104 2e-225 nupG F Nucleoside
HDGFOPHL_01105 7.4e-152 5.4.2.7 G Metalloenzyme superfamily
HDGFOPHL_01106 1.3e-111 GM NmrA-like family
HDGFOPHL_01107 8.2e-44
HDGFOPHL_01108 1.9e-82
HDGFOPHL_01109 1.6e-39
HDGFOPHL_01110 2.4e-60 K HxlR-like helix-turn-helix
HDGFOPHL_01111 2.7e-34
HDGFOPHL_01112 2.5e-99
HDGFOPHL_01114 3e-278
HDGFOPHL_01115 4.3e-59
HDGFOPHL_01116 1.6e-66
HDGFOPHL_01117 5.5e-220 EK Aminotransferase, class I
HDGFOPHL_01118 3.1e-167 K LysR substrate binding domain
HDGFOPHL_01119 3.7e-11 S Protein of unknown function (DUF2922)
HDGFOPHL_01120 5.1e-27
HDGFOPHL_01121 9.9e-100 K DNA-templated transcription, initiation
HDGFOPHL_01122 5.7e-208
HDGFOPHL_01123 1.5e-59
HDGFOPHL_01124 3.1e-53
HDGFOPHL_01125 2e-196 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HDGFOPHL_01126 2.2e-287 macB3 V ABC transporter, ATP-binding protein
HDGFOPHL_01127 1.2e-107 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HDGFOPHL_01128 5.1e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HDGFOPHL_01129 2e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HDGFOPHL_01130 7.3e-147 vdlC S Enoyl-(Acyl carrier protein) reductase
HDGFOPHL_01131 2.8e-129 ybbM S Uncharacterised protein family (UPF0014)
HDGFOPHL_01132 3.4e-115 ybbL S ABC transporter, ATP-binding protein
HDGFOPHL_01133 3.6e-274 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDGFOPHL_01134 2.6e-91
HDGFOPHL_01135 3.5e-88 rmeB K transcriptional regulator, MerR family
HDGFOPHL_01136 2.3e-95 J glyoxalase III activity
HDGFOPHL_01137 1.2e-133 XK27_00890 S Domain of unknown function (DUF368)
HDGFOPHL_01138 1.2e-132 K helix_turn_helix, mercury resistance
HDGFOPHL_01139 1.5e-222 xylR GK ROK family
HDGFOPHL_01140 3.8e-159 akr5f 1.1.1.346 C Aldo keto reductase
HDGFOPHL_01141 4.1e-245 rarA L recombination factor protein RarA
HDGFOPHL_01142 1e-277 rny S Endoribonuclease that initiates mRNA decay
HDGFOPHL_01143 3.3e-121 yoaK S Protein of unknown function (DUF1275)
HDGFOPHL_01144 7.6e-177 D Alpha beta
HDGFOPHL_01145 0.0 pepF2 E Oligopeptidase F
HDGFOPHL_01146 1.2e-73 K Transcriptional regulator
HDGFOPHL_01147 1.5e-163
HDGFOPHL_01148 9.5e-192 S DUF218 domain
HDGFOPHL_01149 1.5e-253 brnQ U Component of the transport system for branched-chain amino acids
HDGFOPHL_01150 2.8e-157 nanK 2.7.1.2 GK ROK family
HDGFOPHL_01151 3.2e-253 frlA E Amino acid permease
HDGFOPHL_01152 2.9e-26
HDGFOPHL_01153 2.6e-27
HDGFOPHL_01155 1.6e-164 S DNA/RNA non-specific endonuclease
HDGFOPHL_01157 4.2e-50
HDGFOPHL_01158 2.5e-77 K Winged helix DNA-binding domain
HDGFOPHL_01159 6.5e-111 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HDGFOPHL_01160 1.3e-102 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HDGFOPHL_01161 7.9e-114
HDGFOPHL_01162 1.8e-178 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDGFOPHL_01163 1.9e-83 iap CBM50 M NlpC P60 family
HDGFOPHL_01164 1.3e-288 ytgP S Polysaccharide biosynthesis protein
HDGFOPHL_01165 3.6e-58 K Helix-turn-helix domain
HDGFOPHL_01166 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
HDGFOPHL_01167 1.7e-168 panE2 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDGFOPHL_01168 8.8e-44
HDGFOPHL_01169 1.9e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDGFOPHL_01170 0.0 yjcE P Sodium proton antiporter
HDGFOPHL_01171 2.2e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HDGFOPHL_01172 1.6e-113 ssuA P NMT1-like family
HDGFOPHL_01173 1.7e-178 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
HDGFOPHL_01174 5.8e-145 yfiQ I Acyltransferase family
HDGFOPHL_01175 1.5e-303 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HDGFOPHL_01176 2.2e-117 yoaK S Protein of unknown function (DUF1275)
HDGFOPHL_01177 3.9e-157 rihA F Inosine-uridine preferring nucleoside hydrolase
HDGFOPHL_01179 3.5e-177 K helix_turn _helix lactose operon repressor
HDGFOPHL_01180 6.1e-29 mcbG S Pentapeptide repeats (8 copies)
HDGFOPHL_01181 1e-99 ywlG S Belongs to the UPF0340 family
HDGFOPHL_01182 6.8e-84 hmpT S ECF-type riboflavin transporter, S component
HDGFOPHL_01183 2.6e-138 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H Phosphomethylpyrimidine kinase
HDGFOPHL_01184 4.5e-258 norG_2 K Aminotransferase class I and II
HDGFOPHL_01185 2.6e-70 4.4.1.5 E Glyoxalase
HDGFOPHL_01186 1.8e-139 S Membrane
HDGFOPHL_01187 2.8e-185 tdh 1.1.1.14 C Zinc-binding dehydrogenase
HDGFOPHL_01188 6.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HDGFOPHL_01189 3.2e-74
HDGFOPHL_01190 9.5e-50 ykkC P Small Multidrug Resistance protein
HDGFOPHL_01191 2.2e-51 sugE P Multidrug resistance protein
HDGFOPHL_01192 1e-98 speG J Acetyltransferase (GNAT) domain
HDGFOPHL_01193 1.8e-145 G Belongs to the phosphoglycerate mutase family
HDGFOPHL_01194 1.1e-18 S integral membrane protein
HDGFOPHL_01195 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
HDGFOPHL_01196 9e-195 nlhH_1 I alpha/beta hydrolase fold
HDGFOPHL_01197 5.8e-250 xylP2 G symporter
HDGFOPHL_01198 8.3e-45 S CRISPR-associated protein (Cas_Csn2)
HDGFOPHL_01199 4.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDGFOPHL_01200 5.4e-95 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDGFOPHL_01201 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HDGFOPHL_01202 2.3e-301 E ABC transporter, substratebinding protein
HDGFOPHL_01203 8.4e-82
HDGFOPHL_01204 2.1e-08
HDGFOPHL_01205 8.9e-176 K Transcriptional regulator, LacI family
HDGFOPHL_01206 1.1e-261 G Major Facilitator
HDGFOPHL_01207 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HDGFOPHL_01208 2.5e-135 C Zinc-binding dehydrogenase
HDGFOPHL_01209 1e-116
HDGFOPHL_01210 1.9e-74 K helix_turn_helix, mercury resistance
HDGFOPHL_01211 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HDGFOPHL_01212 0.0 yicI 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HDGFOPHL_01213 1.4e-259 gph G MFS/sugar transport protein
HDGFOPHL_01214 1.4e-283 uxaC 5.3.1.12 G glucuronate isomerase
HDGFOPHL_01215 1.5e-247 V Polysaccharide biosynthesis C-terminal domain
HDGFOPHL_01216 5.6e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDGFOPHL_01217 8.8e-167 yjjC V ABC transporter
HDGFOPHL_01218 4.7e-283 M Exporter of polyketide antibiotics
HDGFOPHL_01219 7.6e-51 DR0488 S 3D domain
HDGFOPHL_01220 6.6e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDGFOPHL_01221 6.7e-176 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HDGFOPHL_01222 6.4e-167 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HDGFOPHL_01223 1.9e-95 K Bacterial regulatory proteins, tetR family
HDGFOPHL_01225 6.1e-153 picA 3.2.1.67 G Glycosyl hydrolases family 28
HDGFOPHL_01226 1.2e-93 G Xylose isomerase-like TIM barrel
HDGFOPHL_01227 1.1e-246 melB1_1 G MFS/sugar transport protein
HDGFOPHL_01228 1.6e-160 yteR 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HDGFOPHL_01229 3.2e-56 M LysM domain
HDGFOPHL_01230 5.1e-55 M LysM domain protein
HDGFOPHL_01231 1.9e-40 M LysM domain protein
HDGFOPHL_01232 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDGFOPHL_01233 0.0 glpQ 3.1.4.46 C phosphodiesterase
HDGFOPHL_01234 2.2e-93 M1-874 K Domain of unknown function (DUF1836)
HDGFOPHL_01235 0.0 yfgQ P E1-E2 ATPase
HDGFOPHL_01237 1.1e-161 ytbE 1.1.1.346 S Aldo keto reductase
HDGFOPHL_01238 2.5e-259 yjeM E Amino Acid
HDGFOPHL_01239 1.4e-74 hsp O Belongs to the small heat shock protein (HSP20) family
HDGFOPHL_01240 7.6e-61
HDGFOPHL_01241 9.7e-242 yhdP S Transporter associated domain
HDGFOPHL_01242 4.4e-172 K Transcriptional regulator, LacI family
HDGFOPHL_01243 5e-142 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDGFOPHL_01245 3e-249 lmrB EGP Major facilitator Superfamily
HDGFOPHL_01246 3.5e-256 S ATPases associated with a variety of cellular activities
HDGFOPHL_01247 2.6e-85 nrdI F Belongs to the NrdI family
HDGFOPHL_01248 4.8e-134 nfrA 1.5.1.39 C nitroreductase
HDGFOPHL_01249 1.6e-244 glpT G Major Facilitator Superfamily
HDGFOPHL_01250 1.9e-214 yttB EGP Major facilitator Superfamily
HDGFOPHL_01251 4.9e-85
HDGFOPHL_01252 1.1e-155 1.1.1.65 C Aldo keto reductase
HDGFOPHL_01253 3.7e-39 N Uncharacterized conserved protein (DUF2075)
HDGFOPHL_01254 9e-68 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
HDGFOPHL_01255 5.2e-159 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M MucBP domain
HDGFOPHL_01256 7.5e-87 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDGFOPHL_01257 2.7e-63 1.6.5.2 S NADPH-dependent FMN reductase
HDGFOPHL_01258 5.2e-38 T Cyclic nucleotide-binding protein
HDGFOPHL_01259 1.8e-61 S Alpha/beta hydrolase family
HDGFOPHL_01260 3.3e-44 S Alpha/beta hydrolase family
HDGFOPHL_01262 2.6e-178 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HDGFOPHL_01263 5.2e-49 C Flavodoxin
HDGFOPHL_01264 4.2e-56 adhR K MerR, DNA binding
HDGFOPHL_01265 3.6e-77 GM NmrA-like family
HDGFOPHL_01266 1.6e-101 S Alpha beta hydrolase
HDGFOPHL_01267 7.6e-62 yliE T EAL domain
HDGFOPHL_01268 2.6e-27 K helix_turn_helix, mercury resistance
HDGFOPHL_01269 4.9e-50 K Bacterial regulatory proteins, tetR family
HDGFOPHL_01270 2e-80 1.1.1.219 GM Male sterility protein
HDGFOPHL_01271 2.4e-170 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HDGFOPHL_01272 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HDGFOPHL_01273 6.4e-70 K Transcriptional regulator
HDGFOPHL_01274 6.6e-95 qorB 1.6.5.2 GM NmrA-like family
HDGFOPHL_01276 3.3e-138 K Helix-turn-helix domain
HDGFOPHL_01277 2.9e-165
HDGFOPHL_01278 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HDGFOPHL_01279 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HDGFOPHL_01280 3.5e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HDGFOPHL_01281 2.6e-183 xynD 3.5.1.104 G polysaccharide deacetylase
HDGFOPHL_01282 4.1e-57
HDGFOPHL_01283 7.4e-101 GM NAD(P)H-binding
HDGFOPHL_01284 6.9e-181 iolS C Aldo keto reductase
HDGFOPHL_01285 2.2e-227 pbuG S permease
HDGFOPHL_01286 1.8e-15 K toxin-antitoxin pair type II binding
HDGFOPHL_01287 3.2e-22
HDGFOPHL_01289 7.2e-92 K helix_turn_helix multiple antibiotic resistance protein
HDGFOPHL_01290 2.1e-158 drrA V ABC transporter
HDGFOPHL_01291 8.1e-116 drrB U ABC-2 type transporter
HDGFOPHL_01292 5.5e-100 K LysR substrate binding domain
HDGFOPHL_01293 2.9e-88 S Protein of unknown function (DUF554)
HDGFOPHL_01294 2.4e-167 2.5.1.74 H UbiA prenyltransferase family
HDGFOPHL_01295 0.0 S Bacterial membrane protein YfhO
HDGFOPHL_01296 1.2e-86 ccl S QueT transporter
HDGFOPHL_01297 4.5e-18
HDGFOPHL_01298 2.6e-45 M hydrolase, family 25
HDGFOPHL_01299 1.4e-27
HDGFOPHL_01300 1.2e-127 S Bacterial SH3 domain
HDGFOPHL_01301 1.2e-26 M Glycosyl hydrolases family 25
HDGFOPHL_01302 2e-13 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HDGFOPHL_01303 0.0 S Predicted membrane protein (DUF2207)
HDGFOPHL_01304 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HDGFOPHL_01305 5.2e-281 xynT G MFS/sugar transport protein
HDGFOPHL_01306 1.7e-149 rhaS2 K Transcriptional regulator, AraC family
HDGFOPHL_01307 1.4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDGFOPHL_01308 5.2e-22
HDGFOPHL_01309 2.9e-148 F DNA/RNA non-specific endonuclease
HDGFOPHL_01310 4.5e-89
HDGFOPHL_01311 6.3e-10
HDGFOPHL_01313 1.2e-51
HDGFOPHL_01314 2.2e-111 L haloacid dehalogenase-like hydrolase
HDGFOPHL_01315 1.6e-252 pepC 3.4.22.40 E aminopeptidase
HDGFOPHL_01316 8.9e-78 K helix_turn_helix multiple antibiotic resistance protein
HDGFOPHL_01317 5.2e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDGFOPHL_01318 4.5e-217 tcaB EGP Major facilitator Superfamily
HDGFOPHL_01319 1.6e-224 S module of peptide synthetase
HDGFOPHL_01320 1.2e-91 ykhA 3.1.2.20 I Thioesterase superfamily
HDGFOPHL_01321 1.4e-98 J Acetyltransferase (GNAT) domain
HDGFOPHL_01322 4.8e-114 ywnB S NAD(P)H-binding
HDGFOPHL_01323 5.5e-245 brnQ U Component of the transport system for branched-chain amino acids
HDGFOPHL_01324 3.7e-36
HDGFOPHL_01325 2.7e-123 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HDGFOPHL_01326 3e-37
HDGFOPHL_01327 5.7e-54
HDGFOPHL_01328 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDGFOPHL_01329 9.3e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDGFOPHL_01330 1.7e-110 jag S R3H domain protein
HDGFOPHL_01331 1e-145 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDGFOPHL_01332 3.2e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDGFOPHL_01333 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HDGFOPHL_01334 1.7e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDGFOPHL_01335 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDGFOPHL_01336 4.6e-35 yaaA S S4 domain protein YaaA
HDGFOPHL_01337 1.9e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDGFOPHL_01338 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDGFOPHL_01339 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDGFOPHL_01340 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HDGFOPHL_01341 3e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDGFOPHL_01342 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDGFOPHL_01343 3.1e-228 Q Imidazolonepropionase and related amidohydrolases
HDGFOPHL_01344 8.4e-301 E ABC transporter, substratebinding protein
HDGFOPHL_01345 3.4e-138
HDGFOPHL_01346 2.7e-227 Q Imidazolonepropionase and related amidohydrolases
HDGFOPHL_01347 4.9e-301 E ABC transporter, substratebinding protein
HDGFOPHL_01348 2.2e-99 K Bacterial regulatory proteins, tetR family
HDGFOPHL_01349 5.5e-66 S membrane transporter protein
HDGFOPHL_01350 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HDGFOPHL_01351 2.1e-63 rplI J Binds to the 23S rRNA
HDGFOPHL_01353 6e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HDGFOPHL_01354 1.1e-100 S NADPH-dependent FMN reductase
HDGFOPHL_01355 3.5e-211 yttB EGP Major facilitator Superfamily
HDGFOPHL_01356 1.8e-22
HDGFOPHL_01357 2.4e-303 E ABC transporter, substratebinding protein
HDGFOPHL_01358 1.3e-38
HDGFOPHL_01359 6.3e-129 E Matrixin
HDGFOPHL_01361 5.7e-132 K response regulator
HDGFOPHL_01362 0.0 vicK 2.7.13.3 T Histidine kinase
HDGFOPHL_01363 1.1e-237 yycH S YycH protein
HDGFOPHL_01364 1.2e-149 yycI S YycH protein
HDGFOPHL_01365 3.8e-156 vicX 3.1.26.11 S domain protein
HDGFOPHL_01366 6.3e-193 htrA 3.4.21.107 O serine protease
HDGFOPHL_01367 7.3e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDGFOPHL_01368 7.9e-36
HDGFOPHL_01370 2.2e-08 M Mycoplasma protein of unknown function, DUF285
HDGFOPHL_01371 2.2e-71 M Mycoplasma protein of unknown function, DUF285
HDGFOPHL_01372 2.6e-20
HDGFOPHL_01374 1.5e-80
HDGFOPHL_01376 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDGFOPHL_01377 1.3e-74 K Acetyltransferase (GNAT) domain
HDGFOPHL_01378 4.2e-166
HDGFOPHL_01379 4e-39
HDGFOPHL_01380 1.4e-106 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDGFOPHL_01381 1.3e-11 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HDGFOPHL_01382 3.2e-22 S Mor transcription activator family
HDGFOPHL_01383 3.8e-142 ydhO 3.4.14.13 M NlpC/P60 family
HDGFOPHL_01384 2.4e-102 S regulation of response to stimulus
HDGFOPHL_01385 1e-119 lsa S ABC transporter
HDGFOPHL_01386 8.7e-81 argO S LysE type translocator
HDGFOPHL_01387 1.4e-35 mgrA K helix_turn_helix multiple antibiotic resistance protein
HDGFOPHL_01388 3.6e-142 nlhH I Esterase
HDGFOPHL_01389 7.1e-175 draG 3.2.2.24 O ADP-ribosylglycohydrolase
HDGFOPHL_01390 1.7e-97 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HDGFOPHL_01392 4.7e-89 cadD P Cadmium resistance transporter
HDGFOPHL_01393 8.3e-78 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
HDGFOPHL_01394 8.3e-77 gtrA S GtrA-like protein
HDGFOPHL_01395 8.9e-298 E Bacterial extracellular solute-binding proteins, family 5 Middle
HDGFOPHL_01396 8.3e-111 K Bacterial regulatory proteins, tetR family
HDGFOPHL_01397 4e-229 XK27_06930 S ABC-2 family transporter protein
HDGFOPHL_01398 4.3e-131 qmcA O prohibitin homologues
HDGFOPHL_01399 5.7e-55 S protein encoded in hypervariable junctions of pilus gene clusters
HDGFOPHL_01400 3.6e-22
HDGFOPHL_01401 8e-97 GBS0088 S Nucleotidyltransferase
HDGFOPHL_01402 1.8e-84 yybC S Protein of unknown function (DUF2798)
HDGFOPHL_01403 3.4e-56 ydiI Q Thioesterase superfamily
HDGFOPHL_01404 1.1e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HDGFOPHL_01405 2.6e-261 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HDGFOPHL_01406 6.4e-67 S Protein of unknown function (DUF1097)
HDGFOPHL_01407 3.4e-212 preA 1.3.1.1 C 4Fe-4S dicluster domain
HDGFOPHL_01408 5.6e-183 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HDGFOPHL_01412 1.3e-48
HDGFOPHL_01413 7.2e-90 P Cadmium resistance transporter
HDGFOPHL_01414 1.6e-120 sirR K Helix-turn-helix diphteria tox regulatory element
HDGFOPHL_01415 1.5e-71 T Universal stress protein family
HDGFOPHL_01416 8.3e-285 mntH P H( )-stimulated, divalent metal cation uptake system
HDGFOPHL_01417 8.5e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDGFOPHL_01418 2.4e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDGFOPHL_01419 3e-240 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDGFOPHL_01420 3e-122 GM NmrA-like family
HDGFOPHL_01421 4.3e-98 fadR K Bacterial regulatory proteins, tetR family
HDGFOPHL_01422 4.3e-180 D Alpha beta
HDGFOPHL_01423 6.9e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HDGFOPHL_01424 5.7e-166 I Alpha beta
HDGFOPHL_01425 0.0 O Pro-kumamolisin, activation domain
HDGFOPHL_01426 3.6e-114 S Membrane
HDGFOPHL_01427 2e-132 puuD S peptidase C26
HDGFOPHL_01428 3.7e-38
HDGFOPHL_01429 1.4e-113 magIII L Base excision DNA repair protein, HhH-GPD family
HDGFOPHL_01430 6.7e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDGFOPHL_01432 3.4e-76 ssuB P ATPases associated with a variety of cellular activities
HDGFOPHL_01433 2.3e-116 ssuC U Binding-protein-dependent transport system inner membrane component
HDGFOPHL_01434 8.6e-198 M NlpC/P60 family
HDGFOPHL_01435 9.2e-161 G Peptidase_C39 like family
HDGFOPHL_01436 3.8e-104 pncA Q Isochorismatase family
HDGFOPHL_01437 1e-53 K Transcriptional regulator PadR-like family
HDGFOPHL_01438 9.1e-73 XK27_06920 S Protein of unknown function (DUF1700)
HDGFOPHL_01439 5.5e-111 S Putative adhesin
HDGFOPHL_01440 1.6e-185 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDGFOPHL_01441 1.2e-216 fabV 1.3.1.44, 1.3.1.9 I NAD(P)H binding domain of trans-2-enoyl-CoA reductase
HDGFOPHL_01442 5.3e-72 fld C Flavodoxin
HDGFOPHL_01443 4.3e-97 K Acetyltransferase (GNAT) domain
HDGFOPHL_01444 6.2e-241 yifK E Amino acid permease
HDGFOPHL_01445 1.1e-108
HDGFOPHL_01446 4.7e-63 S WxL domain surface cell wall-binding
HDGFOPHL_01447 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HDGFOPHL_01448 5.8e-225 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HDGFOPHL_01449 2.7e-188 adhP 1.1.1.1 C alcohol dehydrogenase
HDGFOPHL_01450 2.2e-67 lrpA K AsnC family
HDGFOPHL_01451 2.8e-163 opuBA E ABC transporter, ATP-binding protein
HDGFOPHL_01452 1.2e-269 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDGFOPHL_01453 6.4e-12 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDGFOPHL_01454 2.3e-196 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HDGFOPHL_01455 1.1e-98 S NADPH-dependent FMN reductase
HDGFOPHL_01456 1.5e-70 K MarR family
HDGFOPHL_01457 0.0 pacL1 P P-type ATPase
HDGFOPHL_01458 3.8e-11 K Helix-turn-helix XRE-family like proteins
HDGFOPHL_01459 2.2e-18
HDGFOPHL_01460 1.7e-88 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HDGFOPHL_01462 3.7e-276 pipD E Dipeptidase
HDGFOPHL_01463 1.1e-149
HDGFOPHL_01464 2.1e-100 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HDGFOPHL_01465 6.1e-117 S Elongation factor G-binding protein, N-terminal
HDGFOPHL_01466 3.8e-168 EG EamA-like transporter family
HDGFOPHL_01467 0.0 copB 3.6.3.4 P P-type ATPase
HDGFOPHL_01468 1.5e-77 copR K Copper transport repressor CopY TcrY
HDGFOPHL_01469 3.4e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDGFOPHL_01470 3.8e-159 S reductase
HDGFOPHL_01471 0.0 ctpA 3.6.3.54 P P-type ATPase
HDGFOPHL_01472 1.3e-63 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HDGFOPHL_01474 2.5e-155 yxkH G Polysaccharide deacetylase
HDGFOPHL_01475 1.5e-157 xerD L Phage integrase, N-terminal SAM-like domain
HDGFOPHL_01476 8.7e-190 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HDGFOPHL_01477 0.0 oatA I Acyltransferase
HDGFOPHL_01478 3.9e-123
HDGFOPHL_01479 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HDGFOPHL_01480 5.9e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDGFOPHL_01481 1.7e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HDGFOPHL_01482 2.4e-34
HDGFOPHL_01483 1.4e-93 K helix_turn_helix multiple antibiotic resistance protein
HDGFOPHL_01484 2e-247 xylP1 G MFS/sugar transport protein
HDGFOPHL_01485 2.3e-98 S Protein of unknown function (DUF1440)
HDGFOPHL_01486 0.0 uvrA2 L ABC transporter
HDGFOPHL_01487 1.9e-65 S Tautomerase enzyme
HDGFOPHL_01488 5.3e-260
HDGFOPHL_01489 1.4e-221
HDGFOPHL_01490 2.1e-109 opuCD P Binding-protein-dependent transport system inner membrane component
HDGFOPHL_01491 1.1e-175 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDGFOPHL_01492 8e-106 opuCB E ABC transporter permease
HDGFOPHL_01493 1.2e-222 opuCA E ABC transporter, ATP-binding protein
HDGFOPHL_01494 4.6e-45
HDGFOPHL_01495 5.9e-222 mdtG EGP Major facilitator Superfamily
HDGFOPHL_01496 1.6e-182 yfeX P Peroxidase
HDGFOPHL_01497 3.6e-229 patB 4.4.1.8 E Aminotransferase, class I
HDGFOPHL_01498 1.8e-108 M Protein of unknown function (DUF3737)
HDGFOPHL_01499 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDGFOPHL_01500 4.4e-186 ykoT GT2 M Glycosyl transferase family 2
HDGFOPHL_01501 2.8e-241 M hydrolase, family 25
HDGFOPHL_01502 4.9e-103
HDGFOPHL_01503 3.1e-196 yubA S AI-2E family transporter
HDGFOPHL_01504 2.7e-160 yclI V FtsX-like permease family
HDGFOPHL_01505 7.1e-121 yclH V ABC transporter
HDGFOPHL_01506 0.0 malL 3.2.1.10, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G Alpha amylase, catalytic domain protein
HDGFOPHL_01507 8.6e-57 K Winged helix DNA-binding domain
HDGFOPHL_01508 1.8e-136 pnuC H nicotinamide mononucleotide transporter
HDGFOPHL_01509 2.4e-151 corA P CorA-like Mg2+ transporter protein
HDGFOPHL_01510 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDGFOPHL_01511 4.1e-66
HDGFOPHL_01512 6.5e-43
HDGFOPHL_01513 3.2e-224 T PhoQ Sensor
HDGFOPHL_01514 2e-126 K Transcriptional regulatory protein, C terminal
HDGFOPHL_01515 3e-26
HDGFOPHL_01516 1.8e-113 ylbE GM NAD(P)H-binding
HDGFOPHL_01517 9.3e-228 ndh 1.6.99.3 C NADH dehydrogenase
HDGFOPHL_01518 4.6e-91 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDGFOPHL_01519 3.7e-102 K Bacterial regulatory proteins, tetR family
HDGFOPHL_01520 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HDGFOPHL_01521 3.5e-100 K Bacterial transcriptional regulator
HDGFOPHL_01522 1.8e-09
HDGFOPHL_01523 2.1e-146 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HDGFOPHL_01524 3.9e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDGFOPHL_01525 5.9e-127 kdgT P 2-keto-3-deoxygluconate permease
HDGFOPHL_01526 1.5e-111 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HDGFOPHL_01527 4.2e-81 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HDGFOPHL_01528 4.1e-39
HDGFOPHL_01529 3.4e-127 IQ reductase
HDGFOPHL_01530 2.4e-240 mntH P H( )-stimulated, divalent metal cation uptake system
HDGFOPHL_01531 4.1e-153 S Uncharacterised protein, DegV family COG1307
HDGFOPHL_01532 1.6e-263 nox C NADH oxidase
HDGFOPHL_01533 2.3e-56 trxA1 O Belongs to the thioredoxin family
HDGFOPHL_01534 5.1e-38 yrkD S Metal-sensitive transcriptional repressor
HDGFOPHL_01535 1.3e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDGFOPHL_01536 5.1e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDGFOPHL_01537 9.6e-147 M1-1017
HDGFOPHL_01538 2.4e-161 I Carboxylesterase family
HDGFOPHL_01539 5.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDGFOPHL_01540 1.7e-159
HDGFOPHL_01541 2.3e-248 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDGFOPHL_01542 5.2e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HDGFOPHL_01543 2.8e-154 lysR5 K LysR substrate binding domain
HDGFOPHL_01544 8.4e-143 yxaA S membrane transporter protein
HDGFOPHL_01545 2e-56 ywjH S Protein of unknown function (DUF1634)
HDGFOPHL_01546 7.8e-140 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HDGFOPHL_01547 1.2e-225 mdtG EGP Major facilitator Superfamily
HDGFOPHL_01548 2.8e-96 2.7.6.5 S RelA SpoT domain protein
HDGFOPHL_01549 8.1e-28 S Protein of unknown function (DUF2929)
HDGFOPHL_01550 5.5e-169 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDGFOPHL_01552 0.0 S membrane
HDGFOPHL_01553 1.8e-119 K cheY-homologous receiver domain
HDGFOPHL_01554 1.1e-234 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HDGFOPHL_01555 6.8e-181 malR K Transcriptional regulator, LacI family
HDGFOPHL_01556 8.6e-254 malT G Major Facilitator
HDGFOPHL_01557 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HDGFOPHL_01558 4.6e-76
HDGFOPHL_01559 6.6e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDGFOPHL_01560 1.2e-151 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HDGFOPHL_01561 1.3e-151 S Alpha/beta hydrolase of unknown function (DUF915)
HDGFOPHL_01562 6.9e-150 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HDGFOPHL_01563 4.6e-64 K MarR family
HDGFOPHL_01564 2.2e-249 yclG M Parallel beta-helix repeats
HDGFOPHL_01565 6.7e-72 spx4 1.20.4.1 P ArsC family
HDGFOPHL_01566 2.1e-132 iap CBM50 M NlpC/P60 family
HDGFOPHL_01567 3.1e-207 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDGFOPHL_01568 3.5e-60 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HDGFOPHL_01569 5.6e-213 ica2 GT2 M Glycosyl transferase family group 2
HDGFOPHL_01570 3.4e-98
HDGFOPHL_01571 5.2e-194
HDGFOPHL_01572 4.9e-295 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDGFOPHL_01573 1.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HDGFOPHL_01574 4.7e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDGFOPHL_01575 3.6e-271 pipD E Dipeptidase
HDGFOPHL_01576 2.5e-278 yjeM E Amino Acid
HDGFOPHL_01577 1.1e-52 S Alpha/beta hydrolase of unknown function (DUF915)
HDGFOPHL_01578 9.7e-136 K Helix-turn-helix
HDGFOPHL_01579 3.7e-36 K Bacterial regulatory proteins, tetR family
HDGFOPHL_01580 1.1e-66 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDGFOPHL_01581 3.1e-69
HDGFOPHL_01582 1.3e-99 rimL J Acetyltransferase (GNAT) domain
HDGFOPHL_01583 9.1e-294 katA 1.11.1.6 C Belongs to the catalase family
HDGFOPHL_01584 4.2e-181 C Aldo/keto reductase family
HDGFOPHL_01585 7.3e-32 adhR K MerR, DNA binding
HDGFOPHL_01586 1.6e-144 K LysR substrate binding domain
HDGFOPHL_01587 6.7e-185 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HDGFOPHL_01588 1.6e-31 yyaQ S YjbR
HDGFOPHL_01589 2.8e-92 ydeA 3.5.1.124 S DJ-1/PfpI family
HDGFOPHL_01590 2.1e-46 N PFAM Uncharacterised protein family UPF0150
HDGFOPHL_01591 1.2e-71 K LytTr DNA-binding domain
HDGFOPHL_01592 3.1e-75 S Protein of unknown function (DUF3021)
HDGFOPHL_01593 4.7e-88 entB 3.5.1.19 Q Isochorismatase family
HDGFOPHL_01594 1.5e-27 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDGFOPHL_01595 8.2e-141 yceJ EGP Major facilitator Superfamily
HDGFOPHL_01596 3.7e-51 yvdC S MazG nucleotide pyrophosphohydrolase domain
HDGFOPHL_01597 2.7e-83 bioY S BioY family
HDGFOPHL_01598 1.2e-138 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDGFOPHL_01599 6.4e-126 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HDGFOPHL_01600 1.6e-140 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HDGFOPHL_01601 4.2e-155 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDGFOPHL_01602 3.5e-266 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HDGFOPHL_01603 3.8e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HDGFOPHL_01604 6.7e-72 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDGFOPHL_01605 4.2e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDGFOPHL_01606 3.2e-122 IQ reductase
HDGFOPHL_01607 3.6e-163 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HDGFOPHL_01608 1.9e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDGFOPHL_01609 6.3e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDGFOPHL_01610 2.1e-79 marR K Transcriptional regulator
HDGFOPHL_01611 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDGFOPHL_01612 2.7e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDGFOPHL_01613 2e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HDGFOPHL_01614 3.5e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDGFOPHL_01615 1.9e-40 ylqC S Belongs to the UPF0109 family
HDGFOPHL_01616 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HDGFOPHL_01617 6.1e-48
HDGFOPHL_01618 3.1e-229 S Putative metallopeptidase domain
HDGFOPHL_01619 1.8e-212 3.1.3.1 S associated with various cellular activities
HDGFOPHL_01620 0.0 pacL 3.6.3.8 P P-type ATPase
HDGFOPHL_01621 8.3e-207 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDGFOPHL_01622 2.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDGFOPHL_01623 1.4e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDGFOPHL_01624 0.0 smc D Required for chromosome condensation and partitioning
HDGFOPHL_01625 2.8e-128 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDGFOPHL_01626 6.4e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDGFOPHL_01627 6.8e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDGFOPHL_01628 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDGFOPHL_01629 9.4e-311 yloV S DAK2 domain fusion protein YloV
HDGFOPHL_01630 5.2e-57 asp S Asp23 family, cell envelope-related function
HDGFOPHL_01631 8.3e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HDGFOPHL_01632 1.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HDGFOPHL_01633 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HDGFOPHL_01634 2.8e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDGFOPHL_01635 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HDGFOPHL_01636 5.2e-128 stp 3.1.3.16 T phosphatase
HDGFOPHL_01637 1.9e-226 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDGFOPHL_01638 8.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDGFOPHL_01639 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDGFOPHL_01640 2.2e-213 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDGFOPHL_01641 4.9e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDGFOPHL_01642 3.3e-104 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HDGFOPHL_01643 7.6e-52
HDGFOPHL_01645 2.9e-64 M domain protein
HDGFOPHL_01646 6.3e-307 recN L May be involved in recombinational repair of damaged DNA
HDGFOPHL_01647 3.7e-76 argR K Regulates arginine biosynthesis genes
HDGFOPHL_01648 2.6e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HDGFOPHL_01649 9.2e-164 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDGFOPHL_01650 8.4e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDGFOPHL_01651 1.2e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDGFOPHL_01652 5.2e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDGFOPHL_01653 7.2e-74 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDGFOPHL_01654 4.8e-73 yqhY S Asp23 family, cell envelope-related function
HDGFOPHL_01655 1.3e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDGFOPHL_01656 2.8e-188 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HDGFOPHL_01657 1.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HDGFOPHL_01658 2.2e-57 ysxB J Cysteine protease Prp
HDGFOPHL_01659 3.4e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HDGFOPHL_01660 5.9e-94 K Transcriptional regulator
HDGFOPHL_01661 5.5e-95 dut S Protein conserved in bacteria
HDGFOPHL_01662 1.8e-178
HDGFOPHL_01663 8.1e-157
HDGFOPHL_01664 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
HDGFOPHL_01665 2.8e-64 glnR K Transcriptional regulator
HDGFOPHL_01666 5.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDGFOPHL_01667 5.4e-141 glpQ 3.1.4.46 C phosphodiesterase
HDGFOPHL_01668 3.1e-23 WQ51_02665 S Protein of unknown function (DUF3042)
HDGFOPHL_01669 2.1e-70 yqhL P Rhodanese-like protein
HDGFOPHL_01670 8.9e-181 glk 2.7.1.2 G Glucokinase
HDGFOPHL_01671 9.3e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HDGFOPHL_01672 2e-118 gluP 3.4.21.105 S Peptidase, S54 family
HDGFOPHL_01673 1.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDGFOPHL_01674 2.5e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDGFOPHL_01675 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HDGFOPHL_01676 1.8e-25 CP_0775 S Domain of unknown function (DUF378)
HDGFOPHL_01677 0.0 S membrane
HDGFOPHL_01678 6.4e-56 yneR S Belongs to the HesB IscA family
HDGFOPHL_01679 6.3e-71 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDGFOPHL_01680 1e-119 udk 2.7.1.48 F Cytidine monophosphokinase
HDGFOPHL_01681 4.2e-206 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDGFOPHL_01682 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDGFOPHL_01683 5.8e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDGFOPHL_01684 8.8e-68 yodB K Transcriptional regulator, HxlR family
HDGFOPHL_01685 4e-92 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDGFOPHL_01686 2.7e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDGFOPHL_01687 8.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HDGFOPHL_01688 3.1e-135 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDGFOPHL_01689 1.7e-69 S Protein of unknown function (DUF1093)
HDGFOPHL_01690 3.2e-292 arlS 2.7.13.3 T Histidine kinase
HDGFOPHL_01691 2.8e-120 K response regulator
HDGFOPHL_01692 1.9e-194 adhP 1.1.1.1 C alcohol dehydrogenase
HDGFOPHL_01693 7.8e-112 zmp3 O Zinc-dependent metalloprotease
HDGFOPHL_01694 1.5e-52 K Transcriptional regulator, ArsR family
HDGFOPHL_01695 7.8e-146 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HDGFOPHL_01696 6.9e-29 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HDGFOPHL_01697 8.6e-96 yceD S Uncharacterized ACR, COG1399
HDGFOPHL_01698 1.9e-214 ylbM S Belongs to the UPF0348 family
HDGFOPHL_01699 2.2e-139 yqeM Q Methyltransferase
HDGFOPHL_01700 1.6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDGFOPHL_01701 1.8e-107 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HDGFOPHL_01702 5.9e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDGFOPHL_01703 1.3e-48 yhbY J RNA-binding protein
HDGFOPHL_01704 1.9e-222 yqeH S Ribosome biogenesis GTPase YqeH
HDGFOPHL_01705 3.2e-103 yqeG S HAD phosphatase, family IIIA
HDGFOPHL_01706 7.8e-113 S regulation of response to stimulus
HDGFOPHL_01707 3.7e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDGFOPHL_01708 5.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HDGFOPHL_01709 4.4e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDGFOPHL_01710 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDGFOPHL_01711 2.9e-165 dnaI L Primosomal protein DnaI
HDGFOPHL_01712 4e-243 dnaB L replication initiation and membrane attachment
HDGFOPHL_01713 7.8e-88 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDGFOPHL_01714 1.8e-110 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDGFOPHL_01715 3.3e-163 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDGFOPHL_01716 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDGFOPHL_01717 7.6e-263 guaD 3.5.4.3 F Amidohydrolase family
HDGFOPHL_01718 9.4e-237 F Permease
HDGFOPHL_01719 7.1e-119 ybhL S Belongs to the BI1 family
HDGFOPHL_01720 1e-133 pnuC H nicotinamide mononucleotide transporter
HDGFOPHL_01721 4.3e-258 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HDGFOPHL_01722 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HDGFOPHL_01723 3.1e-12
HDGFOPHL_01724 3.4e-67 K Transcriptional regulator, HxlR family
HDGFOPHL_01725 1.3e-212 mccF V LD-carboxypeptidase
HDGFOPHL_01726 3.7e-176 rihB 3.2.2.1, 3.2.2.8 F Nucleoside
HDGFOPHL_01727 5.8e-118 yeiL K Cyclic nucleotide-monophosphate binding domain
HDGFOPHL_01728 5.8e-172 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDGFOPHL_01729 6.3e-221 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HDGFOPHL_01730 4e-124 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HDGFOPHL_01731 3.4e-120 S GyrI-like small molecule binding domain
HDGFOPHL_01732 6.6e-222 EGP Major facilitator Superfamily
HDGFOPHL_01733 2.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HDGFOPHL_01734 4.1e-179 hrtB V ABC transporter permease
HDGFOPHL_01735 5.8e-86 ygfC K Bacterial regulatory proteins, tetR family
HDGFOPHL_01736 4.9e-205 ynfM EGP Major facilitator Superfamily
HDGFOPHL_01737 1.7e-82 thiW S Thiamine-precursor transporter protein (ThiW)
HDGFOPHL_01738 1.5e-167 mleP S Sodium Bile acid symporter family
HDGFOPHL_01739 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HDGFOPHL_01740 1.1e-161 mleR K LysR family
HDGFOPHL_01741 1e-145 K Helix-turn-helix domain, rpiR family
HDGFOPHL_01742 1.5e-216 aguA 3.5.3.12 E agmatine deiminase
HDGFOPHL_01743 3.2e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HDGFOPHL_01744 1.1e-216 aguA 3.5.3.12 E agmatine deiminase
HDGFOPHL_01745 1.6e-231 aguD E Amino Acid
HDGFOPHL_01746 2.8e-196 ptcA 2.1.3.3, 2.1.3.6 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDGFOPHL_01747 2.9e-236 nhaC C Na H antiporter NhaC
HDGFOPHL_01748 4.4e-261 E Amino acid permease
HDGFOPHL_01749 0.0 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
HDGFOPHL_01750 1.3e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDGFOPHL_01751 1.3e-38
HDGFOPHL_01754 1.1e-204 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HDGFOPHL_01755 4.3e-26
HDGFOPHL_01756 1.6e-155 EG EamA-like transporter family
HDGFOPHL_01757 3.9e-300 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HDGFOPHL_01758 3e-226 3.6.4.13 M domain protein
HDGFOPHL_01759 8.8e-38
HDGFOPHL_01760 1.2e-12 S Transglycosylase associated protein
HDGFOPHL_01761 8.1e-14 yjdF S Protein of unknown function (DUF2992)
HDGFOPHL_01762 8.3e-154 K Transcriptional regulator
HDGFOPHL_01763 1.6e-304 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HDGFOPHL_01764 3.9e-136 S Belongs to the UPF0246 family
HDGFOPHL_01765 1.6e-236 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDGFOPHL_01766 1.1e-66
HDGFOPHL_01767 3.3e-75 2.7.1.191 G PTS system sorbose subfamily IIB component
HDGFOPHL_01768 6.4e-59 2.7.1.191 G PTS system fructose IIA component
HDGFOPHL_01769 9.5e-153 G system, mannose fructose sorbose family IID component
HDGFOPHL_01770 3.8e-118 G PTS system sorbose-specific iic component
HDGFOPHL_01771 4e-68 G Phosphoglycerate mutase family
HDGFOPHL_01772 2.4e-103 K LysR substrate binding domain
HDGFOPHL_01773 1.7e-108 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDGFOPHL_01774 1.7e-120 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDGFOPHL_01775 2.8e-216 naiP EGP Major facilitator Superfamily
HDGFOPHL_01776 1.4e-130 S Protein of unknown function
HDGFOPHL_01777 6.6e-170 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HDGFOPHL_01778 5.3e-148 G Belongs to the carbohydrate kinase PfkB family
HDGFOPHL_01779 4.7e-252 F Belongs to the purine-cytosine permease (2.A.39) family
HDGFOPHL_01780 7.3e-186 yegU O ADP-ribosylglycohydrolase
HDGFOPHL_01781 4.8e-120 yihL K UTRA
HDGFOPHL_01782 5.2e-38 yhaZ L DNA alkylation repair enzyme
HDGFOPHL_01785 6.6e-13 yhaZ L DNA alkylation repair enzyme
HDGFOPHL_01786 4.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HDGFOPHL_01787 0.0 tetP J elongation factor G
HDGFOPHL_01788 3.4e-230 EK Aminotransferase, class I
HDGFOPHL_01789 1.1e-24
HDGFOPHL_01790 4.2e-207 G Major Facilitator
HDGFOPHL_01791 0.0 3.2.1.55 GH51 G Right handed beta helix region
HDGFOPHL_01792 3.9e-138 K helix_turn_helix, arabinose operon control protein
HDGFOPHL_01793 4.5e-73 S COG NOG18757 non supervised orthologous group
HDGFOPHL_01794 5.8e-203 pmrB EGP Major facilitator Superfamily
HDGFOPHL_01795 3.2e-107 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HDGFOPHL_01796 1.3e-122
HDGFOPHL_01797 3.9e-116 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HDGFOPHL_01798 1.9e-222 LO Uncharacterized conserved protein (DUF2075)
HDGFOPHL_01799 2e-26 K Transcriptional
HDGFOPHL_01800 4.7e-73
HDGFOPHL_01801 1.3e-303 M Mycoplasma protein of unknown function, DUF285
HDGFOPHL_01802 1.2e-100 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HDGFOPHL_01803 2.6e-35 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HDGFOPHL_01804 8.9e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDGFOPHL_01805 5.2e-46
HDGFOPHL_01806 3.9e-75 elaA S Gnat family
HDGFOPHL_01807 1.8e-69 K Transcriptional regulator
HDGFOPHL_01808 1.3e-116 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDGFOPHL_01809 3.8e-148 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDGFOPHL_01810 5.4e-20
HDGFOPHL_01812 1.5e-70 K Helix-turn-helix XRE-family like proteins
HDGFOPHL_01813 3.7e-44
HDGFOPHL_01814 9.3e-110 ylbE GM NAD(P)H-binding
HDGFOPHL_01815 2.7e-55
HDGFOPHL_01816 6.9e-101 ahpC 1.11.1.15 O Peroxiredoxin
HDGFOPHL_01817 8.4e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDGFOPHL_01818 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
HDGFOPHL_01819 1.5e-166 yqhA G Aldose 1-epimerase
HDGFOPHL_01820 1.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
HDGFOPHL_01821 5.3e-189 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDGFOPHL_01822 1.3e-303 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
HDGFOPHL_01823 1.1e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HDGFOPHL_01824 2.6e-129 kdgR K FCD domain
HDGFOPHL_01825 4.4e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HDGFOPHL_01826 1.7e-182 exuR K Periplasmic binding protein domain
HDGFOPHL_01827 1e-276 yjmB G MFS/sugar transport protein
HDGFOPHL_01828 4.8e-309 5.1.2.7 S tagaturonate epimerase
HDGFOPHL_01829 4e-294 uxaC 5.3.1.12 G glucuronate isomerase
HDGFOPHL_01830 6.4e-224 S module of peptide synthetase
HDGFOPHL_01832 2.6e-250 EGP Major facilitator Superfamily
HDGFOPHL_01833 2.5e-20 S Protein of unknown function (DUF3278)
HDGFOPHL_01834 2.2e-19 K Helix-turn-helix XRE-family like proteins
HDGFOPHL_01835 1.1e-63 S Leucine-rich repeat (LRR) protein
HDGFOPHL_01836 8.6e-129
HDGFOPHL_01837 9.9e-91 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDGFOPHL_01838 7.5e-132 gntR1 K UbiC transcription regulator-associated domain protein
HDGFOPHL_01839 6.3e-109 O Zinc-dependent metalloprotease
HDGFOPHL_01840 6.6e-76 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDGFOPHL_01841 3.3e-71
HDGFOPHL_01842 3.4e-135 plnC K LytTr DNA-binding domain
HDGFOPHL_01843 7.9e-204 2.7.13.3 T GHKL domain
HDGFOPHL_01844 7.9e-212 2.1.1.80, 2.7.13.3, 3.1.1.61 T protein histidine kinase activity
HDGFOPHL_01845 1.1e-127 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HDGFOPHL_01847 6.7e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDGFOPHL_01848 2.8e-76 uspA T universal stress protein
HDGFOPHL_01849 2.5e-44 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDGFOPHL_01850 6.9e-168 norB EGP Major Facilitator
HDGFOPHL_01851 1.3e-48 K transcriptional regulator
HDGFOPHL_01852 0.0 oppA1 E ABC transporter substrate-binding protein
HDGFOPHL_01853 1e-173 oppC EP Binding-protein-dependent transport system inner membrane component
HDGFOPHL_01854 9.8e-180 oppB P ABC transporter permease
HDGFOPHL_01855 3.5e-177 oppF P Belongs to the ABC transporter superfamily
HDGFOPHL_01856 6.9e-192 oppD P Belongs to the ABC transporter superfamily
HDGFOPHL_01857 1.6e-79 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HDGFOPHL_01858 3.9e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HDGFOPHL_01859 2.3e-69
HDGFOPHL_01860 2.2e-47
HDGFOPHL_01861 3.4e-16
HDGFOPHL_01863 3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HDGFOPHL_01864 4.8e-290 xylB 2.7.1.12, 2.7.1.16, 2.7.1.17 G Xylulose kinase
HDGFOPHL_01865 1.1e-224 xylT EGP Major facilitator Superfamily
HDGFOPHL_01866 4.3e-141 IQ reductase
HDGFOPHL_01867 1.1e-65 frataxin S Domain of unknown function (DU1801)
HDGFOPHL_01868 0.0 S membrane
HDGFOPHL_01869 4.3e-89 uspA T universal stress protein
HDGFOPHL_01870 3.9e-95 yxkA S Phosphatidylethanolamine-binding protein
HDGFOPHL_01871 1.5e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HDGFOPHL_01872 9.6e-122 kcsA P Ion channel
HDGFOPHL_01873 2.3e-49
HDGFOPHL_01874 3.5e-171 C Aldo keto reductase
HDGFOPHL_01875 4.1e-68
HDGFOPHL_01876 3e-93 Z012_06855 S Acetyltransferase (GNAT) family
HDGFOPHL_01877 2.7e-250 nhaC C Na H antiporter NhaC
HDGFOPHL_01878 2.3e-190 S Membrane transport protein
HDGFOPHL_01879 1.6e-188 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDGFOPHL_01880 2.7e-267 yufL 2.7.13.3 T Single cache domain 3
HDGFOPHL_01881 3.7e-123 malR3 K cheY-homologous receiver domain
HDGFOPHL_01882 8e-172 S ABC-2 family transporter protein
HDGFOPHL_01883 1.4e-101 XK27_06935 K Bacterial regulatory proteins, tetR family
HDGFOPHL_01884 4e-124 yliE T Putative diguanylate phosphodiesterase
HDGFOPHL_01885 1.7e-87 M Belongs to the glycosyl hydrolase 28 family
HDGFOPHL_01886 6.5e-93 wecD K Acetyltransferase (GNAT) family
HDGFOPHL_01888 9.8e-85 F NUDIX domain
HDGFOPHL_01890 1.2e-102 padC Q Phenolic acid decarboxylase
HDGFOPHL_01891 2.2e-82 padR K Virulence activator alpha C-term
HDGFOPHL_01892 2e-74 elaA S Gnat family
HDGFOPHL_01893 2.1e-79 yybA 2.3.1.57 K Transcriptional regulator
HDGFOPHL_01894 4.9e-128 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HDGFOPHL_01895 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HDGFOPHL_01896 3.9e-72 K Transcriptional regulator
HDGFOPHL_01897 8.5e-222
HDGFOPHL_01899 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HDGFOPHL_01900 1.3e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDGFOPHL_01901 5.8e-54 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDGFOPHL_01902 2.2e-78 ywiB S Domain of unknown function (DUF1934)
HDGFOPHL_01903 2.7e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HDGFOPHL_01904 4.8e-265 ywfO S HD domain protein
HDGFOPHL_01905 1.3e-143 yxeH S hydrolase
HDGFOPHL_01906 0.0 xpkA 4.1.2.22, 4.1.2.9 G Phosphoketolase
HDGFOPHL_01907 1.7e-131 gntR K UbiC transcription regulator-associated domain protein
HDGFOPHL_01908 2e-68 racA K helix_turn_helix, mercury resistance
HDGFOPHL_01909 4.8e-55 S Domain of unknown function (DUF3899)
HDGFOPHL_01910 5.5e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDGFOPHL_01911 2.5e-216 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDGFOPHL_01912 1.5e-144 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HDGFOPHL_01915 1.1e-131 znuB U ABC 3 transport family
HDGFOPHL_01916 5.2e-130 fhuC P ABC transporter
HDGFOPHL_01917 2.3e-170 znuA P Belongs to the bacterial solute-binding protein 9 family
HDGFOPHL_01918 9.2e-157 S Prolyl oligopeptidase family
HDGFOPHL_01919 6.4e-86 KTV abc transporter atp-binding protein
HDGFOPHL_01920 7.8e-88 V ABC transporter
HDGFOPHL_01921 5.8e-51 V Transport permease protein
HDGFOPHL_01923 5.5e-86
HDGFOPHL_01924 4.3e-161 2.7.1.2 GK ROK family
HDGFOPHL_01925 9.1e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDGFOPHL_01926 4.2e-209 xylR GK ROK family
HDGFOPHL_01927 2.8e-260 xylP G MFS/sugar transport protein
HDGFOPHL_01928 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
HDGFOPHL_01929 7.1e-109 ung2 3.2.2.27 L Uracil-DNA glycosylase
HDGFOPHL_01930 1.9e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDGFOPHL_01931 4.3e-36 veg S Biofilm formation stimulator VEG
HDGFOPHL_01932 8.5e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDGFOPHL_01933 4.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDGFOPHL_01934 1.8e-147 tatD L hydrolase, TatD family
HDGFOPHL_01935 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDGFOPHL_01936 1.8e-161 yunF F Protein of unknown function DUF72
HDGFOPHL_01937 3.8e-51
HDGFOPHL_01938 6.8e-130 cobB K SIR2 family
HDGFOPHL_01939 1.9e-178
HDGFOPHL_01940 1.2e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HDGFOPHL_01941 5.7e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HDGFOPHL_01942 1.2e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDGFOPHL_01944 0.0 helD 3.6.4.12 L DNA helicase
HDGFOPHL_01945 1.8e-83
HDGFOPHL_01946 1.3e-51
HDGFOPHL_01947 5.2e-176 kdgR K helix_turn _helix lactose operon repressor
HDGFOPHL_01948 3.2e-87 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M sugar phosphate isomerase involved in capsule formation
HDGFOPHL_01949 3.6e-106 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase HUMPS family
HDGFOPHL_01950 2e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HDGFOPHL_01951 8.5e-230 gntT EG Citrate transporter
HDGFOPHL_01952 2.2e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
HDGFOPHL_01953 6.7e-35
HDGFOPHL_01954 2.2e-189 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDGFOPHL_01956 9.1e-36 ygbF S Sugar efflux transporter for intercellular exchange
HDGFOPHL_01957 4.7e-249 gshR 1.8.1.7 C Glutathione reductase
HDGFOPHL_01958 3.6e-206 EGP Major facilitator Superfamily
HDGFOPHL_01959 1.9e-161 ropB K Helix-turn-helix XRE-family like proteins
HDGFOPHL_01960 1.3e-73 S Protein of unknown function (DUF3290)
HDGFOPHL_01961 1.1e-113 yviA S Protein of unknown function (DUF421)
HDGFOPHL_01962 3.4e-94 I NUDIX domain
HDGFOPHL_01963 5.8e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDGFOPHL_01964 5.4e-240 mntH P H( )-stimulated, divalent metal cation uptake system
HDGFOPHL_01965 4.5e-30
HDGFOPHL_01966 2.3e-60 K Winged helix DNA-binding domain
HDGFOPHL_01967 2.3e-251 S Uncharacterized protein conserved in bacteria (DUF2252)
HDGFOPHL_01968 9.2e-278 frvR K Mga helix-turn-helix domain
HDGFOPHL_01969 9.8e-36
HDGFOPHL_01970 1.6e-255 U Belongs to the purine-cytosine permease (2.A.39) family
HDGFOPHL_01971 4.9e-78 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HDGFOPHL_01972 1.7e-84 S Bacterial PH domain
HDGFOPHL_01973 1.3e-265 ydbT S Bacterial PH domain
HDGFOPHL_01974 5.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HDGFOPHL_01975 2.7e-212 EG GntP family permease
HDGFOPHL_01976 6.4e-193 KT Putative sugar diacid recognition
HDGFOPHL_01977 6e-174
HDGFOPHL_01978 1.2e-160 ytrB V ABC transporter, ATP-binding protein
HDGFOPHL_01979 6.1e-61 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HDGFOPHL_01980 3.5e-121 S Protein of unknown function (DUF975)
HDGFOPHL_01981 9.6e-132 XK27_07210 6.1.1.6 S B3/4 domain
HDGFOPHL_01982 0.0 2.8.2.22 M Arylsulfotransferase Ig-like domain
HDGFOPHL_01983 1.5e-19
HDGFOPHL_01984 1.3e-176 xopQ 3.2.2.1, 3.2.2.8 F inosine-uridine preferring nucleoside hydrolase
HDGFOPHL_01985 6.6e-165 ydcZ S Putative inner membrane exporter, YdcZ
HDGFOPHL_01986 4.5e-310 ybiT S ABC transporter, ATP-binding protein
HDGFOPHL_01987 4.4e-155 K helix_turn_helix, arabinose operon control protein
HDGFOPHL_01988 1.9e-209 norA EGP Major facilitator Superfamily
HDGFOPHL_01989 2.9e-154 K LysR substrate binding domain
HDGFOPHL_01990 1.4e-160 MA20_14895 S Conserved hypothetical protein 698
HDGFOPHL_01991 3.1e-102 P Cadmium resistance transporter
HDGFOPHL_01992 2.1e-52 czrA K Transcriptional regulator, ArsR family
HDGFOPHL_01993 0.0 mco Q Multicopper oxidase
HDGFOPHL_01994 2.2e-117 S SNARE associated Golgi protein
HDGFOPHL_01995 0.0 cadA P P-type ATPase
HDGFOPHL_01996 1.8e-195 sdrF M Collagen binding domain
HDGFOPHL_01997 2.7e-70 S Iron-sulphur cluster biosynthesis
HDGFOPHL_01998 3.5e-61 gntR1 K Transcriptional regulator, GntR family
HDGFOPHL_01999 0.0 Q FtsX-like permease family
HDGFOPHL_02000 1.8e-136 cysA V ABC transporter, ATP-binding protein
HDGFOPHL_02001 7.2e-183 S Aldo keto reductase
HDGFOPHL_02002 5.5e-196 ytbD EGP Major facilitator Superfamily
HDGFOPHL_02003 2.4e-62 K Transcriptional regulator, HxlR family
HDGFOPHL_02004 6.4e-168
HDGFOPHL_02005 0.0 2.7.8.12 M glycerophosphotransferase
HDGFOPHL_02006 6.5e-70 K Transcriptional regulator
HDGFOPHL_02007 3.5e-152 1.6.5.2 GM NmrA-like family
HDGFOPHL_02008 4.2e-133 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDGFOPHL_02009 1.7e-123 IQ Enoyl-(Acyl carrier protein) reductase
HDGFOPHL_02010 8e-97 S membrane transporter protein
HDGFOPHL_02011 1.4e-284 E dipeptidase activity
HDGFOPHL_02012 7.2e-139 K acetyltransferase
HDGFOPHL_02013 9.5e-92 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HDGFOPHL_02014 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HDGFOPHL_02015 2.2e-68 S hydrolase
HDGFOPHL_02016 1.9e-32 2.7.1.2 GK Transcriptional regulator
HDGFOPHL_02017 3.4e-102 EGP Major facilitator Superfamily
HDGFOPHL_02018 7.4e-186 galR K Transcriptional regulator
HDGFOPHL_02019 3.2e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HDGFOPHL_02020 3.1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDGFOPHL_02021 5.1e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDGFOPHL_02022 5.6e-248 gph G Transporter
HDGFOPHL_02023 2.6e-36
HDGFOPHL_02024 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HDGFOPHL_02025 1e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HDGFOPHL_02026 6.4e-207 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
HDGFOPHL_02027 7.2e-144 etfB C Electron transfer flavoprotein domain
HDGFOPHL_02028 4e-173 etfA C Electron transfer flavoprotein FAD-binding domain
HDGFOPHL_02029 0.0 oppD EP Psort location Cytoplasmic, score
HDGFOPHL_02030 5e-77 K Transcriptional regulator, LysR family
HDGFOPHL_02031 3e-189 oxlT G Major Facilitator Superfamily
HDGFOPHL_02032 1.5e-126 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDGFOPHL_02033 5.5e-131 IQ Enoyl-(Acyl carrier protein) reductase
HDGFOPHL_02034 1.1e-80 6.3.3.2 S ASCH
HDGFOPHL_02035 1.4e-246 EGP Major facilitator Superfamily
HDGFOPHL_02036 2.3e-23
HDGFOPHL_02037 1.9e-152 map 3.4.11.18 E Methionine Aminopeptidase
HDGFOPHL_02038 2.4e-138 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HDGFOPHL_02039 6.7e-156 hipB K Helix-turn-helix
HDGFOPHL_02040 4.1e-118 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HDGFOPHL_02041 7.5e-70 yeaO S Protein of unknown function, DUF488
HDGFOPHL_02042 3.3e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S HAD-hyrolase-like
HDGFOPHL_02043 2e-77 usp1 T Universal stress protein family
HDGFOPHL_02044 1.4e-263 U Belongs to the BCCT transporter (TC 2.A.15) family
HDGFOPHL_02045 2.7e-114 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HDGFOPHL_02046 2.5e-83 S 3-demethylubiquinone-9 3-methyltransferase
HDGFOPHL_02047 3.6e-143 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDGFOPHL_02048 6.6e-84
HDGFOPHL_02049 3.2e-239 codA 3.5.4.1 F cytosine deaminase
HDGFOPHL_02050 1.5e-46
HDGFOPHL_02051 9.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HDGFOPHL_02052 6.8e-18
HDGFOPHL_02053 1.2e-123 yrkL S Flavodoxin-like fold
HDGFOPHL_02055 6.2e-30
HDGFOPHL_02057 1.5e-36 S Cytochrome B5
HDGFOPHL_02058 2.1e-31 cspC K Cold shock protein
HDGFOPHL_02059 9.1e-107 XK27_00220 S Dienelactone hydrolase family
HDGFOPHL_02060 4.4e-52
HDGFOPHL_02061 1.1e-219 mutY L A G-specific adenine glycosylase
HDGFOPHL_02062 4.7e-299 E Bacterial extracellular solute-binding proteins, family 5 Middle
HDGFOPHL_02063 1.5e-235 pelX M domain, Protein
HDGFOPHL_02064 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDGFOPHL_02065 3.5e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDGFOPHL_02066 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDGFOPHL_02067 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDGFOPHL_02068 1.3e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDGFOPHL_02069 4.2e-71 yabR J RNA binding
HDGFOPHL_02070 9.7e-44 divIC D Septum formation initiator
HDGFOPHL_02071 1.6e-39 yabO J S4 domain protein
HDGFOPHL_02072 9.1e-292 yabM S Polysaccharide biosynthesis protein
HDGFOPHL_02073 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDGFOPHL_02074 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDGFOPHL_02075 2.2e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDGFOPHL_02076 1.1e-251 S Putative peptidoglycan binding domain
HDGFOPHL_02078 1.1e-113 S (CBS) domain
HDGFOPHL_02079 8.1e-61 ndoA L Toxic component of a toxin-antitoxin (TA) module
HDGFOPHL_02081 8.1e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDGFOPHL_02082 2.9e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDGFOPHL_02083 4.1e-209 S nuclear-transcribed mRNA catabolic process, no-go decay
HDGFOPHL_02084 2.1e-240 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDGFOPHL_02085 2.1e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDGFOPHL_02086 1.9e-149
HDGFOPHL_02087 2.6e-142 htpX O Belongs to the peptidase M48B family
HDGFOPHL_02088 9.9e-95 lemA S LemA family
HDGFOPHL_02089 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDGFOPHL_02090 6.2e-251 XK27_00720 S Leucine-rich repeat (LRR) protein
HDGFOPHL_02091 1.4e-109 XK27_00720 S regulation of response to stimulus
HDGFOPHL_02092 4e-110 S Cell surface protein
HDGFOPHL_02093 3.2e-28 S WxL domain surface cell wall-binding
HDGFOPHL_02094 3.8e-16 S WxL domain surface cell wall-binding
HDGFOPHL_02096 9.6e-83 XK27_00720 S regulation of response to stimulus
HDGFOPHL_02097 7.1e-11 S WxL domain surface cell wall-binding
HDGFOPHL_02098 2.8e-10 S WxL domain surface cell wall-binding
HDGFOPHL_02099 2.4e-16 S WxL domain surface cell wall-binding
HDGFOPHL_02100 8.7e-117 srtA 3.4.22.70 M sortase family
HDGFOPHL_02101 4.3e-42 rpmE2 J Ribosomal protein L31
HDGFOPHL_02102 2.8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDGFOPHL_02103 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HDGFOPHL_02106 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HDGFOPHL_02107 6.8e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDGFOPHL_02108 3.3e-118 yjbM 2.7.6.5 S RelA SpoT domain protein
HDGFOPHL_02109 9.9e-112 yjbH Q Thioredoxin
HDGFOPHL_02110 2.5e-158 degV S DegV family
HDGFOPHL_02111 0.0 pepF E oligoendopeptidase F
HDGFOPHL_02112 8.5e-180 coiA 3.6.4.12 S Competence protein
HDGFOPHL_02113 2.3e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDGFOPHL_02114 4.3e-149 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HDGFOPHL_02115 9.8e-217 ecsB U ABC transporter
HDGFOPHL_02116 2.1e-134 ecsA V ABC transporter, ATP-binding protein
HDGFOPHL_02117 2e-82 hit FG histidine triad
HDGFOPHL_02118 9.6e-47
HDGFOPHL_02119 3.8e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDGFOPHL_02120 3.9e-184 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDGFOPHL_02121 0.0 L AAA domain
HDGFOPHL_02122 1.8e-226 yhaO L Ser Thr phosphatase family protein
HDGFOPHL_02123 4.8e-52 yheA S Belongs to the UPF0342 family
HDGFOPHL_02124 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDGFOPHL_02125 1.4e-78 argR K Regulates arginine biosynthesis genes
HDGFOPHL_02126 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HDGFOPHL_02128 1.1e-17
HDGFOPHL_02129 3.7e-227 3.2.1.96, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HDGFOPHL_02130 1.4e-95 1.5.1.3 H RibD C-terminal domain
HDGFOPHL_02131 2.8e-52 S Protein of unknown function (DUF1516)
HDGFOPHL_02132 1.8e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HDGFOPHL_02133 3.3e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
HDGFOPHL_02134 0.0 asnB 6.3.5.4 E Asparagine synthase
HDGFOPHL_02135 1.1e-119 ntcA2 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HDGFOPHL_02136 2e-269 pipD E Peptidase family C69
HDGFOPHL_02137 1.3e-37
HDGFOPHL_02138 0.0
HDGFOPHL_02141 0.0 uvrA3 L ABC transporter
HDGFOPHL_02142 8.2e-104 L Belongs to the 'phage' integrase family
HDGFOPHL_02145 1.7e-45 E IrrE N-terminal-like domain
HDGFOPHL_02146 2.8e-42 yvaO K Helix-turn-helix XRE-family like proteins
HDGFOPHL_02147 2.2e-14
HDGFOPHL_02151 1.2e-24
HDGFOPHL_02152 8.5e-22 S Domain of unknown function (DUF771)
HDGFOPHL_02156 4.4e-28 S DNA protection
HDGFOPHL_02157 2e-69
HDGFOPHL_02158 8.6e-42 dnaD L Helix-turn-helix domain
HDGFOPHL_02159 6.6e-56 K AntA/AntB antirepressor
HDGFOPHL_02160 2.8e-43 S Endodeoxyribonuclease RusA
HDGFOPHL_02163 1.4e-22
HDGFOPHL_02164 4.8e-89 2.1.1.37 L C-5 cytosine-specific DNA methylase
HDGFOPHL_02167 2.9e-44 arpU S Phage transcriptional regulator, ArpU family
HDGFOPHL_02169 7.1e-12
HDGFOPHL_02172 3.8e-18 L Terminase, small subunit
HDGFOPHL_02173 4.1e-157 S phage terminase, large subunit
HDGFOPHL_02176 1e-142 S Phage portal protein, SPP1 Gp6-like
HDGFOPHL_02177 6.7e-22 S head morphogenesis protein, SPP1 gp7 family
HDGFOPHL_02178 2.3e-07 S Domain of unknown function (DUF4355)
HDGFOPHL_02179 2.6e-101 gpG
HDGFOPHL_02181 1.6e-42
HDGFOPHL_02184 5.2e-07 S Protein of unknown function (DUF3383)
HDGFOPHL_02185 2.1e-10
HDGFOPHL_02188 6.9e-125 M Phage tail tape measure protein TP901
HDGFOPHL_02189 2.5e-26 M LysM domain
HDGFOPHL_02190 5.6e-08
HDGFOPHL_02191 4.3e-58
HDGFOPHL_02192 3.8e-12
HDGFOPHL_02194 1.7e-67 Z012_12235 S Baseplate J-like protein
HDGFOPHL_02195 1.1e-07
HDGFOPHL_02196 1.7e-22
HDGFOPHL_02197 6.2e-33
HDGFOPHL_02199 1.7e-27
HDGFOPHL_02202 9.7e-189 M Glycosyl hydrolases family 25
HDGFOPHL_02203 1.2e-36
HDGFOPHL_02204 5.9e-83 K IrrE N-terminal-like domain
HDGFOPHL_02206 1.3e-15
HDGFOPHL_02208 6.2e-70 V Abi-like protein
HDGFOPHL_02209 2.2e-118 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HDGFOPHL_02210 1e-39
HDGFOPHL_02212 2e-17
HDGFOPHL_02219 8.8e-39
HDGFOPHL_02220 1.5e-43 S Uncharacterised protein conserved in bacteria (DUF2313)
HDGFOPHL_02221 5.5e-121 xkdT S Baseplate J-like protein
HDGFOPHL_02222 1.1e-50 S Protein of unknown function (DUF2634)
HDGFOPHL_02223 5.1e-40 S Protein of unknown function (DUF2577)
HDGFOPHL_02224 4.1e-147 yqbQ G PFAM Phage late control gene D protein (GPD)
HDGFOPHL_02225 3.8e-93 S protein containing LysM domain
HDGFOPHL_02226 2.3e-174 S phage tail tape measure protein
HDGFOPHL_02227 1.1e-42 xkdN S Phage XkdN-like tail assembly chaperone protein, TAC
HDGFOPHL_02228 9.8e-83 xkdM S Phage tail tube protein
HDGFOPHL_02229 6.2e-199 xkdK S Phage tail sheath C-terminal domain
HDGFOPHL_02231 3.3e-55
HDGFOPHL_02232 5.2e-66 S Bacteriophage HK97-gp10, putative tail-component
HDGFOPHL_02233 2.4e-51
HDGFOPHL_02234 5.4e-44
HDGFOPHL_02235 6.3e-11 N Bacterial Ig-like domain 2
HDGFOPHL_02236 2.2e-128
HDGFOPHL_02237 1.3e-35 S Phage minor structural protein GP20
HDGFOPHL_02238 9.3e-21 S YjcQ protein
HDGFOPHL_02241 1.6e-162 S Phage Mu protein F like protein
HDGFOPHL_02242 2.3e-233 S Phage portal protein, SPP1 Gp6-like
HDGFOPHL_02243 9.7e-204 S Terminase RNAseH like domain
HDGFOPHL_02244 4.6e-28 L Terminase small subunit
HDGFOPHL_02245 1.3e-34 S Domain of unknown function (DUF4393)
HDGFOPHL_02246 4.4e-51
HDGFOPHL_02249 5.1e-44 S Protein of unknwon function (DUF3310)
HDGFOPHL_02251 2.8e-11
HDGFOPHL_02252 1.2e-29 S VRR_NUC
HDGFOPHL_02253 0.0 S Phage plasmid primase, P4
HDGFOPHL_02254 2.9e-81 S Protein of unknown function (DUF669)
HDGFOPHL_02255 3.6e-200 res L Helicase C-terminal domain protein
HDGFOPHL_02256 4.5e-119 S AAA domain
HDGFOPHL_02257 1.9e-126 S Protein of unknown function (DUF1351)
HDGFOPHL_02262 9.5e-08
HDGFOPHL_02263 2.5e-26 ps115 K Helix-turn-helix XRE-family like proteins
HDGFOPHL_02264 6.9e-21 S Pfam:Peptidase_M78
HDGFOPHL_02265 7.1e-28 S Short C-terminal domain
HDGFOPHL_02266 6.4e-19
HDGFOPHL_02267 6.9e-71 int L Belongs to the 'phage' integrase family
HDGFOPHL_02269 5.1e-47
HDGFOPHL_02270 2.1e-83 V VanZ like family
HDGFOPHL_02271 3.9e-96 tnpR1 L Resolvase, N terminal domain
HDGFOPHL_02272 2.6e-247 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HDGFOPHL_02273 8.5e-93
HDGFOPHL_02274 3.5e-226 Z012_07420 3.1.21.5 V Z1 domain
HDGFOPHL_02275 1.6e-105 L NgoFVII restriction endonuclease
HDGFOPHL_02276 1e-188 2.1.1.37 H C-5 cytosine-specific DNA methylase
HDGFOPHL_02277 4.2e-226 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HDGFOPHL_02278 2.5e-47
HDGFOPHL_02279 1.5e-59
HDGFOPHL_02280 3.3e-143 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDGFOPHL_02281 1.3e-166 L Psort location Cytoplasmic, score
HDGFOPHL_02282 4.9e-31
HDGFOPHL_02283 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDGFOPHL_02284 5.7e-60
HDGFOPHL_02285 4.1e-150
HDGFOPHL_02286 5.6e-57
HDGFOPHL_02287 3.8e-263 traK U COG3505 Type IV secretory pathway, VirD4 components
HDGFOPHL_02288 6e-74
HDGFOPHL_02289 3.4e-56 CO COG0526, thiol-disulfide isomerase and thioredoxins
HDGFOPHL_02290 5.9e-85
HDGFOPHL_02291 9e-204 M CHAP domain
HDGFOPHL_02292 4.9e-220 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
HDGFOPHL_02293 0.0 traE U Psort location Cytoplasmic, score
HDGFOPHL_02294 2.9e-114
HDGFOPHL_02295 1.5e-35
HDGFOPHL_02296 2.3e-51 S Cag pathogenicity island, type IV secretory system
HDGFOPHL_02297 3.4e-101
HDGFOPHL_02298 4e-50
HDGFOPHL_02299 0.0 traA L MobA MobL family protein
HDGFOPHL_02300 8.1e-26
HDGFOPHL_02301 1.2e-37
HDGFOPHL_02302 2.8e-232 N Uncharacterized conserved protein (DUF2075)
HDGFOPHL_02303 9e-92 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HDGFOPHL_02304 8.7e-136 yhfI S Metallo-beta-lactamase superfamily
HDGFOPHL_02305 1e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDGFOPHL_02306 1e-112 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDGFOPHL_02307 3.6e-106 T EAL domain
HDGFOPHL_02308 3.3e-86
HDGFOPHL_02309 4.7e-249 pgaC GT2 M Glycosyl transferase
HDGFOPHL_02310 5.9e-100 ytqB J Putative rRNA methylase
HDGFOPHL_02311 1.3e-114 pgpB1 3.6.1.27 I Acid phosphatase homologues
HDGFOPHL_02312 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDGFOPHL_02313 7e-33
HDGFOPHL_02314 3.2e-121 P ABC-type multidrug transport system ATPase component
HDGFOPHL_02315 4.8e-145 S NADPH-dependent FMN reductase
HDGFOPHL_02316 7.1e-50
HDGFOPHL_02317 2e-297 ytgP S Polysaccharide biosynthesis protein
HDGFOPHL_02318 1.2e-123 rluB 5.4.99.19, 5.4.99.20, 5.4.99.21, 5.4.99.22 J pseudouridine synthase activity
HDGFOPHL_02319 4.3e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDGFOPHL_02320 1.5e-266 pepV 3.5.1.18 E dipeptidase PepV
HDGFOPHL_02321 7.7e-83 uspA T Belongs to the universal stress protein A family
HDGFOPHL_02322 5.8e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HDGFOPHL_02323 1.1e-242 cycA E Amino acid permease
HDGFOPHL_02324 2e-55 ytzB S Small secreted protein
HDGFOPHL_02325 4e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDGFOPHL_02326 1.4e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDGFOPHL_02327 2.3e-170
HDGFOPHL_02328 1.9e-294 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDGFOPHL_02329 6.5e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HDGFOPHL_02330 1.3e-279 E amino acid
HDGFOPHL_02331 8.9e-107 dhaS K Bacterial regulatory proteins, tetR family
HDGFOPHL_02332 5.4e-16 1.1.1.1 C nadph quinone reductase
HDGFOPHL_02335 2.2e-210 lmrP E Major Facilitator Superfamily
HDGFOPHL_02336 5.5e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HDGFOPHL_02337 1.1e-286 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDGFOPHL_02338 9.3e-167
HDGFOPHL_02339 2e-75 nreC K PFAM regulatory protein LuxR
HDGFOPHL_02340 1.8e-78 comP 2.7.13.3 F Sensor histidine kinase
HDGFOPHL_02341 2.9e-101 hipB K Helix-turn-helix
HDGFOPHL_02342 3.5e-36 yitW S Iron-sulfur cluster assembly protein
HDGFOPHL_02343 8.8e-254 sufB O assembly protein SufB
HDGFOPHL_02344 5.2e-60 nifU C SUF system FeS assembly protein, NifU family
HDGFOPHL_02345 5e-184 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDGFOPHL_02346 3e-136 sufD O FeS assembly protein SufD
HDGFOPHL_02347 1.1e-125 sufC O FeS assembly ATPase SufC
HDGFOPHL_02348 1.9e-12 feoA P FeoA domain
HDGFOPHL_02349 4.6e-256 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HDGFOPHL_02351 4.9e-154 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HDGFOPHL_02352 2.3e-159 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HDGFOPHL_02354 1.8e-164 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HDGFOPHL_02356 7e-81 vat S acetyltransferase, isoleucine patch superfamily
HDGFOPHL_02357 1.2e-72 vat S acetyltransferase, isoleucine patch superfamily
HDGFOPHL_02358 3.2e-153 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HDGFOPHL_02359 1.1e-188 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HDGFOPHL_02360 1e-242 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HDGFOPHL_02372 2.5e-84 zmp2 O Zinc-dependent metalloprotease
HDGFOPHL_02373 1.7e-51 ybjQ S Belongs to the UPF0145 family
HDGFOPHL_02374 5.4e-93
HDGFOPHL_02375 3e-46
HDGFOPHL_02376 3.7e-107
HDGFOPHL_02377 3.7e-213 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDGFOPHL_02378 9.5e-259 bmr3 EGP Major facilitator Superfamily
HDGFOPHL_02379 1.8e-56 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HDGFOPHL_02380 7.7e-120 dck 2.7.1.74 F Deoxynucleoside kinase
HDGFOPHL_02381 2.9e-142 S haloacid dehalogenase-like hydrolase
HDGFOPHL_02382 2.4e-108 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HDGFOPHL_02383 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HDGFOPHL_02384 9.5e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDGFOPHL_02385 2.9e-35
HDGFOPHL_02386 5e-122 S CAAX protease self-immunity
HDGFOPHL_02387 9.4e-83 ohrR K Transcriptional regulator
HDGFOPHL_02388 6.6e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HDGFOPHL_02389 7.7e-79 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDGFOPHL_02390 1e-295 E amino acid
HDGFOPHL_02391 2.3e-117 S membrane
HDGFOPHL_02392 1.9e-113 S VIT family
HDGFOPHL_02393 5.7e-91 perR P Belongs to the Fur family
HDGFOPHL_02394 4.7e-167 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HDGFOPHL_02396 1e-126 yibF S overlaps another CDS with the same product name
HDGFOPHL_02397 4e-201 yibE S overlaps another CDS with the same product name
HDGFOPHL_02399 2.8e-82 uspA T Belongs to the universal stress protein A family
HDGFOPHL_02400 5e-130
HDGFOPHL_02401 1.5e-86 K helix_turn_helix multiple antibiotic resistance protein
HDGFOPHL_02403 3.5e-32 K helix_turn_helix, arabinose operon control protein
HDGFOPHL_02404 1e-26 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HDGFOPHL_02405 1.1e-54 L recombinase activity
HDGFOPHL_02406 7.9e-66 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HDGFOPHL_02407 2.2e-63 arsD S Arsenical resistance operon trans-acting repressor ArsD
HDGFOPHL_02408 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
HDGFOPHL_02409 5.6e-231 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HDGFOPHL_02410 5e-51
HDGFOPHL_02411 9.3e-21 arsD S Arsenical resistance operon trans-acting repressor ArsD
HDGFOPHL_02412 7.9e-263 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDGFOPHL_02413 3.2e-62 K Transcriptional regulator
HDGFOPHL_02414 3.2e-102 cadD P Cadmium resistance transporter
HDGFOPHL_02416 4e-24
HDGFOPHL_02417 0.0 mco Q Multicopper oxidase
HDGFOPHL_02418 1e-238 EGP Major Facilitator Superfamily
HDGFOPHL_02419 4.9e-55
HDGFOPHL_02420 1.2e-23 S Family of unknown function (DUF5388)
HDGFOPHL_02421 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HDGFOPHL_02422 3.1e-41
HDGFOPHL_02423 7.2e-27
HDGFOPHL_02424 0.0 traA L MobA MobL family protein
HDGFOPHL_02425 2.2e-241 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDGFOPHL_02426 4.8e-34
HDGFOPHL_02427 1.7e-84 dps P Belongs to the Dps family
HDGFOPHL_02429 5.3e-136 K Helix-turn-helix domain
HDGFOPHL_02430 5.4e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HDGFOPHL_02431 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HDGFOPHL_02432 3.4e-106 L Integrase
HDGFOPHL_02433 4.1e-62
HDGFOPHL_02434 9.3e-29
HDGFOPHL_02436 5.6e-260 M domain protein
HDGFOPHL_02437 3.1e-119 D Cellulose biosynthesis protein BcsQ
HDGFOPHL_02439 7.9e-207 npr 1.11.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HDGFOPHL_02441 5.3e-11 M COG3209 Rhs family protein
HDGFOPHL_02443 2.7e-21
HDGFOPHL_02446 3.5e-45 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HDGFOPHL_02448 1.1e-230 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HDGFOPHL_02449 1.2e-87 S Protein of unknown function, DUF536
HDGFOPHL_02450 1.2e-171 L Initiator Replication protein
HDGFOPHL_02451 1.6e-196 tra L COG2826 Transposase and inactivated derivatives, IS30 family
HDGFOPHL_02453 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
HDGFOPHL_02454 4.7e-51 repA S Replication initiator protein A
HDGFOPHL_02456 1.4e-33 ydaT
HDGFOPHL_02457 1.2e-07
HDGFOPHL_02466 6.3e-93 L Transposase and inactivated derivatives, IS30 family
HDGFOPHL_02467 4.4e-80 L Transposase
HDGFOPHL_02468 2.7e-31 L Transposase
HDGFOPHL_02470 8.3e-37 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)