ORF_ID e_value Gene_name EC_number CAZy COGs Description
IFHFLOFL_00001 1.4e-158 lysR5 K LysR substrate binding domain
IFHFLOFL_00002 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
IFHFLOFL_00003 3e-251 G Major Facilitator
IFHFLOFL_00004 1.6e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IFHFLOFL_00005 9.4e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IFHFLOFL_00006 9.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IFHFLOFL_00007 1.1e-278 yjeM E Amino Acid
IFHFLOFL_00008 3e-08
IFHFLOFL_00010 2.7e-97 M lysozyme activity
IFHFLOFL_00013 3.7e-08
IFHFLOFL_00016 6.7e-113 S N-acetylmuramoyl-L-alanine amidase activity
IFHFLOFL_00017 3.3e-212 S Phage minor structural protein
IFHFLOFL_00018 1.5e-119 S Phage tail protein
IFHFLOFL_00019 0.0 M Phage tail tape measure protein TP901
IFHFLOFL_00021 2.1e-08 S Pfam:Phage_TTP_1
IFHFLOFL_00025 1.1e-36 S Phage gp6-like head-tail connector protein
IFHFLOFL_00026 7.3e-209 S peptidase activity
IFHFLOFL_00027 3.4e-113 S Clp protease
IFHFLOFL_00028 3e-162 S Phage portal protein
IFHFLOFL_00030 1.4e-227 S Phage Terminase
IFHFLOFL_00032 4.6e-66 L Phage terminase, small subunit
IFHFLOFL_00033 3e-87 S HNH endonuclease
IFHFLOFL_00034 1.9e-75 arpU S Phage transcriptional regulator, ArpU family
IFHFLOFL_00036 1e-42 L Belongs to the 'phage' integrase family
IFHFLOFL_00037 4e-07
IFHFLOFL_00040 2.4e-88 L Psort location Cytoplasmic, score
IFHFLOFL_00043 5.5e-33
IFHFLOFL_00051 1.2e-17
IFHFLOFL_00052 7e-13
IFHFLOFL_00054 1.7e-15 K Cro/C1-type HTH DNA-binding domain
IFHFLOFL_00056 9.6e-30
IFHFLOFL_00057 1.4e-106 K BRO family, N-terminal domain
IFHFLOFL_00058 2e-30 K Protein of unknown function (DUF739)
IFHFLOFL_00059 3.3e-79 3.4.21.88 K Peptidase S24-like
IFHFLOFL_00061 5.3e-46 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IFHFLOFL_00063 3.9e-09
IFHFLOFL_00064 5.8e-37
IFHFLOFL_00065 1.7e-33 S Domain of unknown function (DUF4393)
IFHFLOFL_00067 6.4e-38 S Phage integrase family
IFHFLOFL_00068 3.7e-104 S Phage integrase family
IFHFLOFL_00069 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IFHFLOFL_00070 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IFHFLOFL_00071 9.3e-124 srtA 3.4.22.70 M sortase family
IFHFLOFL_00072 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IFHFLOFL_00073 4.5e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IFHFLOFL_00074 0.0 dnaK O Heat shock 70 kDa protein
IFHFLOFL_00075 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IFHFLOFL_00076 2.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IFHFLOFL_00077 6.7e-121 S GyrI-like small molecule binding domain
IFHFLOFL_00078 1.6e-282 lsa S ABC transporter
IFHFLOFL_00079 7.6e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IFHFLOFL_00080 1.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IFHFLOFL_00081 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IFHFLOFL_00082 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IFHFLOFL_00083 6e-46 rplGA J ribosomal protein
IFHFLOFL_00084 2e-46 ylxR K Protein of unknown function (DUF448)
IFHFLOFL_00085 1.1e-217 nusA K Participates in both transcription termination and antitermination
IFHFLOFL_00086 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
IFHFLOFL_00087 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IFHFLOFL_00088 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IFHFLOFL_00089 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IFHFLOFL_00090 3.4e-138 cdsA 2.7.7.41 S Belongs to the CDS family
IFHFLOFL_00091 5.5e-135 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IFHFLOFL_00092 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IFHFLOFL_00093 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IFHFLOFL_00094 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IFHFLOFL_00095 2.8e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
IFHFLOFL_00096 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
IFHFLOFL_00097 9.8e-117 plsC 2.3.1.51 I Acyltransferase
IFHFLOFL_00098 8.6e-201 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IFHFLOFL_00099 6.1e-300 mdlB V ABC transporter
IFHFLOFL_00100 0.0 mdlA V ABC transporter
IFHFLOFL_00101 1.5e-30 yneF S Uncharacterised protein family (UPF0154)
IFHFLOFL_00102 1.5e-34 ynzC S UPF0291 protein
IFHFLOFL_00103 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IFHFLOFL_00104 1.1e-115 ung2 3.2.2.27 L Uracil-DNA glycosylase
IFHFLOFL_00105 6.5e-75 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IFHFLOFL_00106 9.3e-118 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IFHFLOFL_00107 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IFHFLOFL_00108 2.2e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IFHFLOFL_00109 7.4e-97 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IFHFLOFL_00110 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IFHFLOFL_00111 1.4e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IFHFLOFL_00112 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IFHFLOFL_00113 1.6e-287 pipD E Dipeptidase
IFHFLOFL_00114 7.8e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IFHFLOFL_00115 0.0 smc D Required for chromosome condensation and partitioning
IFHFLOFL_00116 1.6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IFHFLOFL_00117 0.0 oppA E ABC transporter substrate-binding protein
IFHFLOFL_00118 2.8e-298 oppA E ABC transporter substrate-binding protein
IFHFLOFL_00119 3.2e-30 oppA E ABC transporter substrate-binding protein
IFHFLOFL_00120 2.1e-163 oppC P Binding-protein-dependent transport system inner membrane component
IFHFLOFL_00121 7.5e-180 oppB P ABC transporter permease
IFHFLOFL_00122 4.4e-180 oppF P Belongs to the ABC transporter superfamily
IFHFLOFL_00123 1.1e-192 oppD P Belongs to the ABC transporter superfamily
IFHFLOFL_00124 2.6e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IFHFLOFL_00125 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IFHFLOFL_00126 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IFHFLOFL_00127 9.6e-308 yloV S DAK2 domain fusion protein YloV
IFHFLOFL_00128 1.4e-57 asp S Asp23 family, cell envelope-related function
IFHFLOFL_00129 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IFHFLOFL_00130 1e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
IFHFLOFL_00131 5.9e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IFHFLOFL_00132 1.4e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IFHFLOFL_00133 0.0 KLT serine threonine protein kinase
IFHFLOFL_00134 4.5e-140 stp 3.1.3.16 T phosphatase
IFHFLOFL_00135 1.2e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IFHFLOFL_00136 7.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IFHFLOFL_00137 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IFHFLOFL_00138 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IFHFLOFL_00139 4.7e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
IFHFLOFL_00140 4.6e-48
IFHFLOFL_00141 5e-264 recN L May be involved in recombinational repair of damaged DNA
IFHFLOFL_00142 3.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IFHFLOFL_00143 7.8e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IFHFLOFL_00144 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IFHFLOFL_00145 3.6e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IFHFLOFL_00146 8.1e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IFHFLOFL_00147 8e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IFHFLOFL_00148 3.7e-73 yqhY S Asp23 family, cell envelope-related function
IFHFLOFL_00149 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IFHFLOFL_00150 9.5e-195 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IFHFLOFL_00151 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IFHFLOFL_00152 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IFHFLOFL_00153 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
IFHFLOFL_00154 1.2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IFHFLOFL_00155 6.3e-246 S Uncharacterized protein conserved in bacteria (DUF2325)
IFHFLOFL_00156 1.2e-12
IFHFLOFL_00157 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IFHFLOFL_00158 1.2e-92 S ECF-type riboflavin transporter, S component
IFHFLOFL_00159 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IFHFLOFL_00160 1.4e-59
IFHFLOFL_00161 5.2e-56 K Acetyltransferase (GNAT) domain
IFHFLOFL_00162 1.3e-285 S Predicted membrane protein (DUF2207)
IFHFLOFL_00163 9.3e-08
IFHFLOFL_00164 9.3e-80
IFHFLOFL_00165 4.9e-67 S Putative adhesin
IFHFLOFL_00166 5e-79 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IFHFLOFL_00167 3.6e-78 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IFHFLOFL_00168 2.4e-22 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IFHFLOFL_00169 7.1e-40
IFHFLOFL_00170 3.3e-185 yfdV S Membrane transport protein
IFHFLOFL_00171 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IFHFLOFL_00172 1.8e-272 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IFHFLOFL_00173 1.3e-93
IFHFLOFL_00174 3.9e-98 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IFHFLOFL_00175 3.1e-58 yjdF S Protein of unknown function (DUF2992)
IFHFLOFL_00176 2.1e-50 S Domain of unknown function (DUF4160)
IFHFLOFL_00177 7.9e-51
IFHFLOFL_00179 5.7e-44 yjdF S Protein of unknown function (DUF2992)
IFHFLOFL_00180 1.8e-112 1.6.5.2 S Flavodoxin-like fold
IFHFLOFL_00181 6.5e-93 K Bacterial regulatory proteins, tetR family
IFHFLOFL_00182 3.6e-67 doc S Fic/DOC family
IFHFLOFL_00183 4.1e-37
IFHFLOFL_00184 5.5e-133 K Helix-turn-helix
IFHFLOFL_00186 1.6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IFHFLOFL_00187 6.6e-134 K DNA-binding helix-turn-helix protein
IFHFLOFL_00188 5.3e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IFHFLOFL_00189 6e-236 pbuX F xanthine permease
IFHFLOFL_00190 2.2e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IFHFLOFL_00191 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IFHFLOFL_00192 1.3e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IFHFLOFL_00193 6e-73 S Domain of unknown function (DUF1934)
IFHFLOFL_00194 3.3e-266 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
IFHFLOFL_00195 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
IFHFLOFL_00196 9.7e-155 malG P ABC transporter permease
IFHFLOFL_00197 1.4e-253 malF P Binding-protein-dependent transport system inner membrane component
IFHFLOFL_00198 5e-229 malE G Bacterial extracellular solute-binding protein
IFHFLOFL_00199 3.6e-210 msmX P Belongs to the ABC transporter superfamily
IFHFLOFL_00200 7.1e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IFHFLOFL_00201 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IFHFLOFL_00202 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IFHFLOFL_00203 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IFHFLOFL_00204 1.2e-174 yvdE K helix_turn _helix lactose operon repressor
IFHFLOFL_00205 2.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IFHFLOFL_00206 1.1e-219 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IFHFLOFL_00207 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IFHFLOFL_00208 7.4e-36 veg S Biofilm formation stimulator VEG
IFHFLOFL_00209 4.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IFHFLOFL_00210 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IFHFLOFL_00211 6.1e-148 tatD L hydrolase, TatD family
IFHFLOFL_00212 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IFHFLOFL_00213 6.1e-92 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IFHFLOFL_00214 4.7e-100 S TPM domain
IFHFLOFL_00215 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
IFHFLOFL_00216 2.6e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IFHFLOFL_00217 2.3e-113 E Belongs to the SOS response-associated peptidase family
IFHFLOFL_00219 1.3e-114
IFHFLOFL_00220 1.9e-158 ypbG 2.7.1.2 GK ROK family
IFHFLOFL_00221 1.2e-282 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFHFLOFL_00222 1.7e-268 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFHFLOFL_00223 2e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IFHFLOFL_00224 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
IFHFLOFL_00225 1e-133 gmuR K UTRA
IFHFLOFL_00226 5.6e-117 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFHFLOFL_00227 6.4e-167 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFHFLOFL_00228 3.4e-42 S Domain of unknown function (DUF3284)
IFHFLOFL_00229 1.4e-127 yydK K UTRA
IFHFLOFL_00230 1.4e-248 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFHFLOFL_00231 3.4e-56
IFHFLOFL_00232 3.4e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFHFLOFL_00233 9.5e-77 hsp O Belongs to the small heat shock protein (HSP20) family
IFHFLOFL_00234 2.7e-36
IFHFLOFL_00235 1.8e-292 hsdM 2.1.1.72 V type I restriction-modification system
IFHFLOFL_00236 4.1e-119 3.1.21.3 V Type I restriction modification DNA specificity domain
IFHFLOFL_00237 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
IFHFLOFL_00238 0.0 S Protein of unknown function DUF262
IFHFLOFL_00239 0.0 1.3.5.4 C FMN_bind
IFHFLOFL_00240 7.2e-92
IFHFLOFL_00241 9.2e-109
IFHFLOFL_00242 3.8e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IFHFLOFL_00243 6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IFHFLOFL_00244 7.6e-115 hlyIII S protein, hemolysin III
IFHFLOFL_00245 3.8e-151 DegV S Uncharacterised protein, DegV family COG1307
IFHFLOFL_00246 2e-35 yozE S Belongs to the UPF0346 family
IFHFLOFL_00247 1.1e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IFHFLOFL_00248 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IFHFLOFL_00249 9.8e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IFHFLOFL_00250 5.8e-152 dprA LU DNA protecting protein DprA
IFHFLOFL_00251 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IFHFLOFL_00252 1.8e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IFHFLOFL_00253 2e-169 xerC D Phage integrase, N-terminal SAM-like domain
IFHFLOFL_00254 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IFHFLOFL_00255 2e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IFHFLOFL_00256 4.2e-177 lacX 5.1.3.3 G Aldose 1-epimerase
IFHFLOFL_00257 2.6e-98 K LysR substrate binding domain
IFHFLOFL_00258 1.6e-97 S LexA-binding, inner membrane-associated putative hydrolase
IFHFLOFL_00259 8.9e-62
IFHFLOFL_00260 1.1e-179 MA20_14895 S Conserved hypothetical protein 698
IFHFLOFL_00261 2.2e-69 K Transcriptional regulator
IFHFLOFL_00262 5.4e-47
IFHFLOFL_00263 2.6e-42
IFHFLOFL_00264 1.8e-41 K peptidyl-tyrosine sulfation
IFHFLOFL_00265 1.7e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_00266 2e-74 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_00268 2.1e-109 ybbL S ABC transporter, ATP-binding protein
IFHFLOFL_00269 1.5e-130 ybbM S Uncharacterised protein family (UPF0014)
IFHFLOFL_00270 2.1e-96 K Acetyltransferase (GNAT) domain
IFHFLOFL_00271 3.7e-51 S Protein of unknown function (DUF3021)
IFHFLOFL_00272 8.7e-75 K LytTr DNA-binding domain
IFHFLOFL_00273 6.2e-104 S Protein of unknown function (DUF1211)
IFHFLOFL_00274 8.2e-25 L Transposase
IFHFLOFL_00275 5.5e-228 S domain, Protein
IFHFLOFL_00276 8.8e-66 S domain, Protein
IFHFLOFL_00278 3.9e-23 bamA UW LPXTG-motif cell wall anchor domain protein
IFHFLOFL_00279 0.0 bamA UW LPXTG-motif cell wall anchor domain protein
IFHFLOFL_00280 0.0 M domain protein
IFHFLOFL_00281 4.1e-301
IFHFLOFL_00282 1.8e-110 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IFHFLOFL_00283 3.9e-113 3.6.1.55 F NUDIX domain
IFHFLOFL_00284 5.8e-63 S Putative adhesin
IFHFLOFL_00285 9.2e-248 brnQ U Component of the transport system for branched-chain amino acids
IFHFLOFL_00286 1.4e-11 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IFHFLOFL_00287 2.7e-32 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IFHFLOFL_00288 4.5e-17 L Plasmid pRiA4b ORF-3-like protein
IFHFLOFL_00289 5.2e-68 K HxlR family
IFHFLOFL_00290 2.7e-48
IFHFLOFL_00291 5.1e-231 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
IFHFLOFL_00292 2.5e-11 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
IFHFLOFL_00293 3e-76 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
IFHFLOFL_00294 3e-181 dnaQ 2.7.7.7 L EXOIII
IFHFLOFL_00295 7.5e-141 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IFHFLOFL_00296 1.3e-111 yviA S Protein of unknown function (DUF421)
IFHFLOFL_00297 6.4e-73 S Protein of unknown function (DUF3290)
IFHFLOFL_00298 8.8e-245 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IFHFLOFL_00299 1.1e-78 S PAS domain
IFHFLOFL_00300 3.9e-110 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
IFHFLOFL_00302 1e-193 pts36C G iic component
IFHFLOFL_00303 2.1e-09 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IFHFLOFL_00304 3.5e-50 pts36A 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
IFHFLOFL_00305 1.8e-59 K DeoR C terminal sensor domain
IFHFLOFL_00306 1.1e-79 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IFHFLOFL_00307 2.4e-57 yxeH S hydrolase
IFHFLOFL_00308 1.5e-143 pnuC H nicotinamide mononucleotide transporter
IFHFLOFL_00309 0.0 M domain protein
IFHFLOFL_00310 9.3e-104 GM domain, Protein
IFHFLOFL_00311 7.5e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IFHFLOFL_00312 6.1e-43 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_00313 6.2e-126 S PAS domain
IFHFLOFL_00314 4.6e-181 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IFHFLOFL_00315 9.1e-206 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
IFHFLOFL_00316 1.1e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IFHFLOFL_00317 3e-58
IFHFLOFL_00318 0.0 uvrA3 L excinuclease ABC, A subunit
IFHFLOFL_00319 0.0 oppA E ABC transporter substrate-binding protein
IFHFLOFL_00320 3.6e-101 S PFAM Archaeal ATPase
IFHFLOFL_00321 4.7e-155 EG EamA-like transporter family
IFHFLOFL_00322 7.7e-102 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFHFLOFL_00323 1.9e-145 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFHFLOFL_00324 2e-49 bglP 2.7.1.211 G phosphotransferase system
IFHFLOFL_00325 4e-282 bglP 2.7.1.211 G phosphotransferase system
IFHFLOFL_00326 1.6e-132 licT K CAT RNA binding domain
IFHFLOFL_00327 0.0 fhaB M Rib/alpha-like repeat
IFHFLOFL_00328 3.7e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IFHFLOFL_00329 5.3e-161 coaA 2.7.1.33 F Pantothenic acid kinase
IFHFLOFL_00330 3.4e-103 E GDSL-like Lipase/Acylhydrolase
IFHFLOFL_00331 9.5e-242 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFHFLOFL_00332 3.8e-82 rarA L MgsA AAA+ ATPase C terminal
IFHFLOFL_00333 2.3e-122 K Helix-turn-helix domain, rpiR family
IFHFLOFL_00334 1.8e-130 yvpB S Peptidase_C39 like family
IFHFLOFL_00335 5.1e-146 S cog cog1373
IFHFLOFL_00336 0.0 helD 3.6.4.12 L DNA helicase
IFHFLOFL_00337 6.2e-80 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IFHFLOFL_00339 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
IFHFLOFL_00340 6e-61 yugI 5.3.1.9 J general stress protein
IFHFLOFL_00341 4.8e-179 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IFHFLOFL_00342 2.7e-117 dedA S SNARE-like domain protein
IFHFLOFL_00343 8.6e-105 S Protein of unknown function (DUF1461)
IFHFLOFL_00344 3.6e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IFHFLOFL_00345 9.1e-98 yutD S Protein of unknown function (DUF1027)
IFHFLOFL_00346 3.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IFHFLOFL_00347 2e-55
IFHFLOFL_00348 8e-268 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IFHFLOFL_00349 1.2e-274 pepV 3.5.1.18 E dipeptidase PepV
IFHFLOFL_00350 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
IFHFLOFL_00351 3.6e-177 ccpA K catabolite control protein A
IFHFLOFL_00352 5.9e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IFHFLOFL_00353 4e-51
IFHFLOFL_00355 2e-158 ykuT M mechanosensitive ion channel
IFHFLOFL_00356 5.9e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IFHFLOFL_00357 2.2e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IFHFLOFL_00358 6.5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IFHFLOFL_00359 2.4e-68 yslB S Protein of unknown function (DUF2507)
IFHFLOFL_00360 6.6e-53 trxA O Belongs to the thioredoxin family
IFHFLOFL_00361 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IFHFLOFL_00362 1.6e-91 cvpA S Colicin V production protein
IFHFLOFL_00363 1.8e-50 yrzB S Belongs to the UPF0473 family
IFHFLOFL_00364 1.4e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IFHFLOFL_00365 2.6e-42 yrzL S Belongs to the UPF0297 family
IFHFLOFL_00366 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IFHFLOFL_00367 1.5e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IFHFLOFL_00368 6.6e-184 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IFHFLOFL_00369 1.4e-209 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IFHFLOFL_00370 1.1e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IFHFLOFL_00371 4.5e-31 yajC U Preprotein translocase
IFHFLOFL_00372 1.4e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IFHFLOFL_00373 1.6e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IFHFLOFL_00374 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IFHFLOFL_00375 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IFHFLOFL_00376 0.0 nisT V ABC transporter
IFHFLOFL_00377 0.0 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
IFHFLOFL_00378 1.7e-62 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
IFHFLOFL_00379 8.2e-296 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IFHFLOFL_00380 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IFHFLOFL_00382 1.3e-123 liaI S membrane
IFHFLOFL_00383 1e-78 XK27_02470 K LytTr DNA-binding domain
IFHFLOFL_00384 1.3e-99 yvdD 3.2.2.10 S Belongs to the LOG family
IFHFLOFL_00385 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IFHFLOFL_00386 0.0 uup S ABC transporter, ATP-binding protein
IFHFLOFL_00387 8.3e-68
IFHFLOFL_00388 5.9e-94 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
IFHFLOFL_00389 1.6e-127 terC P Integral membrane protein TerC family
IFHFLOFL_00390 1.5e-64 yeaO S Protein of unknown function, DUF488
IFHFLOFL_00391 1.2e-106 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IFHFLOFL_00392 9.7e-281 glnP P ABC transporter permease
IFHFLOFL_00393 9.6e-138 glnQ E ABC transporter, ATP-binding protein
IFHFLOFL_00394 3.7e-162 L HNH nucleases
IFHFLOFL_00395 4.5e-120 yfbR S HD containing hydrolase-like enzyme
IFHFLOFL_00396 5.4e-214 G Glycosyl hydrolases family 8
IFHFLOFL_00397 3.7e-246 ydaM M Glycosyl transferase
IFHFLOFL_00399 1.7e-154
IFHFLOFL_00400 1.7e-16
IFHFLOFL_00401 1.3e-69 S Iron-sulphur cluster biosynthesis
IFHFLOFL_00402 5.4e-182 ybiR P Citrate transporter
IFHFLOFL_00403 9.9e-92 lemA S LemA family
IFHFLOFL_00404 3.8e-146 htpX O Belongs to the peptidase M48B family
IFHFLOFL_00405 1.5e-169 K helix_turn_helix, arabinose operon control protein
IFHFLOFL_00406 4.8e-94 S ABC-type cobalt transport system, permease component
IFHFLOFL_00407 4.3e-250 cbiO1 S ABC transporter, ATP-binding protein
IFHFLOFL_00408 2.1e-109 P Cobalt transport protein
IFHFLOFL_00409 9.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IFHFLOFL_00410 3.5e-182 htrA 3.4.21.107 O serine protease
IFHFLOFL_00411 3.3e-149 vicX 3.1.26.11 S domain protein
IFHFLOFL_00412 1.4e-142 yycI S YycH protein
IFHFLOFL_00413 3.5e-252 yycH S YycH protein
IFHFLOFL_00414 0.0 vicK 2.7.13.3 T Histidine kinase
IFHFLOFL_00415 1.2e-129 K response regulator
IFHFLOFL_00418 4.3e-149 arbV 2.3.1.51 I Acyl-transferase
IFHFLOFL_00419 3.2e-155 arbx M Glycosyl transferase family 8
IFHFLOFL_00420 9.4e-183 arbY M Glycosyl transferase family 8
IFHFLOFL_00421 2.5e-183 arbY M Glycosyl transferase family 8
IFHFLOFL_00422 3.3e-163 arbZ I Phosphate acyltransferases
IFHFLOFL_00423 4.6e-236 yhjX_2 P Major Facilitator Superfamily
IFHFLOFL_00424 1.7e-249 yhjX_2 P Major Facilitator Superfamily
IFHFLOFL_00425 1.2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IFHFLOFL_00426 3.2e-88 S Peptidase propeptide and YPEB domain
IFHFLOFL_00427 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IFHFLOFL_00428 2.5e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IFHFLOFL_00429 4.4e-242 brnQ U Component of the transport system for branched-chain amino acids
IFHFLOFL_00430 0.0 1.3.5.4 C FAD binding domain
IFHFLOFL_00431 2.4e-164 K LysR substrate binding domain
IFHFLOFL_00432 1.6e-266 E amino acid
IFHFLOFL_00433 0.0 3.1.31.1 M domain protein
IFHFLOFL_00434 0.0 infB UW LPXTG-motif cell wall anchor domain protein
IFHFLOFL_00435 1.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IFHFLOFL_00436 7.8e-216 iscS2 2.8.1.7 E Aminotransferase class V
IFHFLOFL_00437 5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IFHFLOFL_00438 7.8e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IFHFLOFL_00439 4.2e-211 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IFHFLOFL_00440 0.0 3.6.3.8 P P-type ATPase
IFHFLOFL_00441 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IFHFLOFL_00442 2.8e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IFHFLOFL_00443 9.2e-124 S Haloacid dehalogenase-like hydrolase
IFHFLOFL_00444 1.4e-110 radC L DNA repair protein
IFHFLOFL_00445 6.5e-166 mreB D cell shape determining protein MreB
IFHFLOFL_00446 1e-143 mreC M Involved in formation and maintenance of cell shape
IFHFLOFL_00447 5.4e-95 mreD
IFHFLOFL_00448 3.6e-13 S Protein of unknown function (DUF4044)
IFHFLOFL_00449 6.1e-52 S Protein of unknown function (DUF3397)
IFHFLOFL_00450 4.1e-77 mraZ K Belongs to the MraZ family
IFHFLOFL_00451 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IFHFLOFL_00452 6.3e-55 ftsL D Cell division protein FtsL
IFHFLOFL_00453 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IFHFLOFL_00454 1.6e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IFHFLOFL_00455 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IFHFLOFL_00456 3.6e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IFHFLOFL_00457 6.3e-154 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IFHFLOFL_00458 2.7e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IFHFLOFL_00459 4.1e-232 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IFHFLOFL_00460 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IFHFLOFL_00461 2e-27 yggT S YGGT family
IFHFLOFL_00462 4.8e-148 ylmH S S4 domain protein
IFHFLOFL_00463 2.4e-112 gpsB D DivIVA domain protein
IFHFLOFL_00464 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IFHFLOFL_00465 2e-32 cspA K 'Cold-shock' DNA-binding domain
IFHFLOFL_00466 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IFHFLOFL_00468 5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IFHFLOFL_00469 3.3e-214 iscS 2.8.1.7 E Aminotransferase class V
IFHFLOFL_00470 1.6e-57 XK27_04120 S Putative amino acid metabolism
IFHFLOFL_00471 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IFHFLOFL_00472 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IFHFLOFL_00473 5.1e-116 S Repeat protein
IFHFLOFL_00474 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IFHFLOFL_00475 9.9e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IFHFLOFL_00476 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IFHFLOFL_00477 3e-34 ykzG S Belongs to the UPF0356 family
IFHFLOFL_00478 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IFHFLOFL_00479 0.0 typA T GTP-binding protein TypA
IFHFLOFL_00480 2.5e-209 ftsW D Belongs to the SEDS family
IFHFLOFL_00481 6.1e-52 ylbG S UPF0298 protein
IFHFLOFL_00482 1.6e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IFHFLOFL_00483 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IFHFLOFL_00484 2.5e-186 ylbL T Belongs to the peptidase S16 family
IFHFLOFL_00485 2.4e-79 comEA L Competence protein ComEA
IFHFLOFL_00486 2e-42 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
IFHFLOFL_00487 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
IFHFLOFL_00488 2.2e-139
IFHFLOFL_00489 2e-105 speG J Acetyltransferase (GNAT) domain
IFHFLOFL_00490 1e-09 K sequence-specific DNA binding
IFHFLOFL_00491 1.3e-54 K sequence-specific DNA binding
IFHFLOFL_00492 1.2e-141 S Protein of unknown function (DUF975)
IFHFLOFL_00493 1.6e-128 qmcA O prohibitin homologues
IFHFLOFL_00494 2.6e-149 ropB K Helix-turn-helix domain
IFHFLOFL_00495 2e-294 V ABC-type multidrug transport system, ATPase and permease components
IFHFLOFL_00496 1.7e-84 C nitroreductase
IFHFLOFL_00497 5e-282 V ABC transporter transmembrane region
IFHFLOFL_00498 1.1e-48
IFHFLOFL_00499 4.5e-36 K Acetyltransferase (GNAT) domain
IFHFLOFL_00500 1.2e-22 K Acetyltransferase (GNAT) domain
IFHFLOFL_00501 1.9e-152 S Protein of unknown function (DUF2785)
IFHFLOFL_00502 1.6e-48 S MazG-like family
IFHFLOFL_00503 2.1e-63
IFHFLOFL_00504 1.4e-135
IFHFLOFL_00506 6e-143 3.1.3.48 T Tyrosine phosphatase family
IFHFLOFL_00507 3.6e-151 S Fic/DOC family
IFHFLOFL_00508 2.7e-51 S endonuclease activity
IFHFLOFL_00509 2.5e-43
IFHFLOFL_00510 1.4e-98 rimL J Acetyltransferase (GNAT) domain
IFHFLOFL_00511 2.6e-88 2.3.1.57 K Acetyltransferase (GNAT) family
IFHFLOFL_00512 1.6e-137 2.4.2.3 F Phosphorylase superfamily
IFHFLOFL_00513 1.8e-83 6.3.3.2 S ASCH
IFHFLOFL_00514 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IFHFLOFL_00515 6.1e-160 rbsU U ribose uptake protein RbsU
IFHFLOFL_00516 1.4e-158 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
IFHFLOFL_00517 1.1e-289 V ABC-type multidrug transport system, ATPase and permease components
IFHFLOFL_00518 1.6e-272 V ABC-type multidrug transport system, ATPase and permease components
IFHFLOFL_00519 5.2e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IFHFLOFL_00520 4.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IFHFLOFL_00521 3e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IFHFLOFL_00522 4.4e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
IFHFLOFL_00523 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IFHFLOFL_00524 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IFHFLOFL_00525 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IFHFLOFL_00526 2.1e-77 ypmB S Protein conserved in bacteria
IFHFLOFL_00527 2.9e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IFHFLOFL_00528 6.7e-116 dnaD L DnaD domain protein
IFHFLOFL_00529 1.2e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IFHFLOFL_00530 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IFHFLOFL_00531 1.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IFHFLOFL_00532 4.2e-106 ypsA S Belongs to the UPF0398 family
IFHFLOFL_00533 7.3e-266 yxbA 6.3.1.12 S ATP-grasp enzyme
IFHFLOFL_00534 0.0 asnB 6.3.5.4 E Asparagine synthase
IFHFLOFL_00535 3.1e-275 S Calcineurin-like phosphoesterase
IFHFLOFL_00536 7.3e-83
IFHFLOFL_00537 5.4e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IFHFLOFL_00538 1.6e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IFHFLOFL_00539 1.6e-140 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IFHFLOFL_00540 9.8e-169 phnD P Phosphonate ABC transporter
IFHFLOFL_00542 3.8e-87 uspA T universal stress protein
IFHFLOFL_00543 5.7e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
IFHFLOFL_00544 1.5e-132 XK27_08440 K UTRA domain
IFHFLOFL_00545 4.9e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IFHFLOFL_00546 3.3e-88 ntd 2.4.2.6 F Nucleoside
IFHFLOFL_00547 1.4e-189
IFHFLOFL_00548 2.3e-207 S zinc-ribbon domain
IFHFLOFL_00549 1.3e-18 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_00550 9.3e-68 2.7.1.191 G PTS system fructose IIA component
IFHFLOFL_00551 5.5e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
IFHFLOFL_00552 1.9e-140 XK27_08455 G PTS system sorbose-specific iic component
IFHFLOFL_00553 8.7e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
IFHFLOFL_00554 1.8e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IFHFLOFL_00555 2.4e-217 agaS G SIS domain
IFHFLOFL_00556 5.3e-130 XK27_08435 K UTRA
IFHFLOFL_00557 0.0 G Belongs to the glycosyl hydrolase 31 family
IFHFLOFL_00558 2.2e-156 I alpha/beta hydrolase fold
IFHFLOFL_00559 4.9e-118 yibF S overlaps another CDS with the same product name
IFHFLOFL_00560 1.4e-187 yibE S overlaps another CDS with the same product name
IFHFLOFL_00561 1.3e-141 yjcE P Sodium proton antiporter
IFHFLOFL_00562 6.5e-117 yjcE P Sodium proton antiporter
IFHFLOFL_00563 3.3e-95
IFHFLOFL_00564 2.8e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IFHFLOFL_00565 7.2e-286 S Cysteine-rich secretory protein family
IFHFLOFL_00566 1.1e-139
IFHFLOFL_00567 6.4e-114 luxT K Bacterial regulatory proteins, tetR family
IFHFLOFL_00568 2.8e-241 cycA E Amino acid permease
IFHFLOFL_00569 4.2e-220 S CAAX protease self-immunity
IFHFLOFL_00570 4.5e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IFHFLOFL_00571 1.4e-62
IFHFLOFL_00572 6.9e-124 S Alpha/beta hydrolase family
IFHFLOFL_00573 2.2e-143 2.4.1.293 GT2 M Glycosyltransferase like family 2
IFHFLOFL_00574 2.4e-162 ypuA S Protein of unknown function (DUF1002)
IFHFLOFL_00575 6.2e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IFHFLOFL_00576 6.3e-176 S Alpha/beta hydrolase of unknown function (DUF915)
IFHFLOFL_00577 5.6e-124 yugP S Putative neutral zinc metallopeptidase
IFHFLOFL_00578 1.9e-272 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IFHFLOFL_00579 6.7e-81
IFHFLOFL_00580 6.9e-89 cobB K SIR2 family
IFHFLOFL_00581 8.9e-47 higA K Helix-turn-helix XRE-family like proteins
IFHFLOFL_00582 4.5e-48 S RelE-like toxin of type II toxin-antitoxin system HigB
IFHFLOFL_00583 1.2e-20
IFHFLOFL_00584 1.1e-192 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IFHFLOFL_00585 9.3e-74 nrdI F NrdI Flavodoxin like
IFHFLOFL_00586 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IFHFLOFL_00587 4.1e-121 L Transposase and inactivated derivatives, IS30 family
IFHFLOFL_00588 8.6e-23 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IFHFLOFL_00589 8.2e-204 gatC G PTS system sugar-specific permease component
IFHFLOFL_00590 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IFHFLOFL_00591 1e-56 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IFHFLOFL_00592 5.6e-119 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IFHFLOFL_00594 5.9e-77 S Fic/DOC family
IFHFLOFL_00595 2.4e-75 L Resolvase, N terminal domain
IFHFLOFL_00596 2.3e-30 K Antidote-toxin recognition MazE, bacterial antitoxin
IFHFLOFL_00597 2e-29
IFHFLOFL_00599 1.8e-66 V N-6 DNA Methylase
IFHFLOFL_00600 1.6e-24 S Type I restriction modification DNA specificity domain
IFHFLOFL_00601 7.4e-185 L N-6 DNA Methylase
IFHFLOFL_00603 2.4e-31 N PFAM Uncharacterised protein family UPF0150
IFHFLOFL_00605 1.3e-09 S Protein of unknown function (DUF669)
IFHFLOFL_00606 1.2e-118 res L Helicase C-terminal domain protein
IFHFLOFL_00612 9.5e-41 lemA S LemA family
IFHFLOFL_00614 1.9e-14 S TPM domain
IFHFLOFL_00615 3.3e-21
IFHFLOFL_00620 2e-14 S Domain of Unknown Function with PDB structure (DUF3850)
IFHFLOFL_00622 3.6e-45 ybl78 L DnaD domain protein
IFHFLOFL_00624 1e-12 2.6.1.2, 2.6.1.66 K sequence-specific DNA binding
IFHFLOFL_00626 2.5e-79
IFHFLOFL_00627 6.7e-25 S HicB_like antitoxin of bacterial toxin-antitoxin system
IFHFLOFL_00628 1.3e-30
IFHFLOFL_00629 1.2e-54 doc S Fic/DOC family
IFHFLOFL_00630 1.4e-43 gepA S Protein of unknown function (DUF4065)
IFHFLOFL_00631 8.1e-27
IFHFLOFL_00632 1.8e-223 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IFHFLOFL_00633 5.2e-57 gepA K Protein of unknown function (DUF4065)
IFHFLOFL_00634 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IFHFLOFL_00635 7.7e-43
IFHFLOFL_00636 3.9e-256 pepC 3.4.22.40 E aminopeptidase
IFHFLOFL_00637 8.8e-124 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IFHFLOFL_00638 3.7e-262 pepC 3.4.22.40 E aminopeptidase
IFHFLOFL_00640 6.3e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IFHFLOFL_00641 0.0 XK27_08315 M Sulfatase
IFHFLOFL_00642 1.1e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IFHFLOFL_00643 5.6e-195 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IFHFLOFL_00644 9e-172 yqhA G Aldose 1-epimerase
IFHFLOFL_00645 7.8e-152 glcU U sugar transport
IFHFLOFL_00646 9.3e-119
IFHFLOFL_00647 8e-179 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IFHFLOFL_00648 3.2e-69 2.4.1.83 GT2 S GtrA-like protein
IFHFLOFL_00649 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IFHFLOFL_00650 3.8e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IFHFLOFL_00651 1.4e-74 S PAS domain
IFHFLOFL_00652 2.9e-148
IFHFLOFL_00653 4e-131
IFHFLOFL_00654 1.7e-179 S Oxidoreductase family, NAD-binding Rossmann fold
IFHFLOFL_00655 0.0 yjbQ P TrkA C-terminal domain protein
IFHFLOFL_00656 1.1e-144 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
IFHFLOFL_00657 1.5e-250 lysA2 M Glycosyl hydrolases family 25
IFHFLOFL_00658 8.6e-265 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IFHFLOFL_00659 1.4e-34 S Protein of unknown function (DUF2922)
IFHFLOFL_00660 1.7e-28
IFHFLOFL_00661 2e-109
IFHFLOFL_00662 1.7e-72
IFHFLOFL_00663 0.0 kup P Transport of potassium into the cell
IFHFLOFL_00664 0.0 kup P Transport of potassium into the cell
IFHFLOFL_00665 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
IFHFLOFL_00666 3e-116 ywnB S NAD(P)H-binding
IFHFLOFL_00667 4.6e-224 S Sterol carrier protein domain
IFHFLOFL_00669 4.9e-201 S Aldo keto reductase
IFHFLOFL_00670 1.3e-85 S Protein of unknown function (DUF3278)
IFHFLOFL_00671 1.2e-20 WQ51_00220 K Helix-turn-helix XRE-family like proteins
IFHFLOFL_00672 7.9e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IFHFLOFL_00674 3.9e-117 yhiD S MgtC family
IFHFLOFL_00675 0.0
IFHFLOFL_00676 8.2e-218 I Protein of unknown function (DUF2974)
IFHFLOFL_00677 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IFHFLOFL_00678 1.1e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IFHFLOFL_00679 4.8e-76 rplI J Binds to the 23S rRNA
IFHFLOFL_00680 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IFHFLOFL_00681 1.6e-155 corA P CorA-like Mg2+ transporter protein
IFHFLOFL_00682 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IFHFLOFL_00683 1.7e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IFHFLOFL_00684 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
IFHFLOFL_00685 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IFHFLOFL_00686 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IFHFLOFL_00687 4.5e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IFHFLOFL_00688 3.9e-19 yaaA S S4 domain
IFHFLOFL_00689 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IFHFLOFL_00690 7e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IFHFLOFL_00691 9.4e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IFHFLOFL_00692 6.6e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IFHFLOFL_00693 3.7e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IFHFLOFL_00694 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IFHFLOFL_00695 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IFHFLOFL_00696 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IFHFLOFL_00697 6.6e-270 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IFHFLOFL_00698 5.2e-284 clcA P chloride
IFHFLOFL_00699 1.2e-201 EGP Major facilitator Superfamily
IFHFLOFL_00700 1.7e-151 ropB K Transcriptional regulator
IFHFLOFL_00701 1.3e-71
IFHFLOFL_00702 1.5e-115 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IFHFLOFL_00703 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IFHFLOFL_00704 6.5e-69 S Iron-sulphur cluster biosynthesis
IFHFLOFL_00705 2.3e-232 EGP Sugar (and other) transporter
IFHFLOFL_00706 2.3e-75 K Acetyltransferase (GNAT) domain
IFHFLOFL_00707 1e-248 ynbB 4.4.1.1 P aluminum resistance
IFHFLOFL_00708 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
IFHFLOFL_00709 4.1e-286 E Amino acid permease
IFHFLOFL_00710 0.0 pepO 3.4.24.71 O Peptidase family M13
IFHFLOFL_00711 4.4e-155 ropB K Helix-turn-helix XRE-family like proteins
IFHFLOFL_00712 0.0 copA 3.6.3.54 P P-type ATPase
IFHFLOFL_00713 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IFHFLOFL_00714 6.3e-66 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IFHFLOFL_00715 1.4e-77 atkY K Penicillinase repressor
IFHFLOFL_00716 5.5e-90
IFHFLOFL_00717 4.1e-90
IFHFLOFL_00718 3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IFHFLOFL_00719 1.1e-226 pbuG S permease
IFHFLOFL_00720 3.4e-46 I bis(5'-adenosyl)-triphosphatase activity
IFHFLOFL_00721 2.3e-232 pbuG S permease
IFHFLOFL_00722 4.1e-109 K helix_turn_helix, mercury resistance
IFHFLOFL_00724 3e-232 pbuG S permease
IFHFLOFL_00725 6e-238 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IFHFLOFL_00726 3.7e-125 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IFHFLOFL_00727 7.7e-120 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IFHFLOFL_00728 1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IFHFLOFL_00729 9.8e-160 yeaE S Aldo/keto reductase family
IFHFLOFL_00730 3.6e-19 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_00731 4.6e-150 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
IFHFLOFL_00732 1.7e-92 agaC G PTS system sorbose-specific iic component
IFHFLOFL_00733 1.3e-121 G PTS system mannose/fructose/sorbose family IID component
IFHFLOFL_00734 2.2e-27 G PTS system fructose IIA component
IFHFLOFL_00735 1.2e-132 S membrane transporter protein
IFHFLOFL_00736 2e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IFHFLOFL_00737 4.1e-130 3.5.2.6 V Beta-lactamase enzyme family
IFHFLOFL_00738 5.7e-189 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IFHFLOFL_00739 3.2e-88 blaA6 V Beta-lactamase
IFHFLOFL_00740 1.3e-52 2.7.1.191 G PTS system sorbose subfamily IIB component
IFHFLOFL_00741 1e-119 G PTS system mannose/fructose/sorbose family IID component
IFHFLOFL_00742 2e-99 G PTS system sorbose-specific iic component
IFHFLOFL_00743 5.3e-177 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
IFHFLOFL_00744 4.8e-173 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
IFHFLOFL_00745 7.1e-195 tcsA S ABC transporter substrate-binding protein PnrA-like
IFHFLOFL_00746 1.2e-166 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
IFHFLOFL_00747 1.1e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IFHFLOFL_00748 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IFHFLOFL_00749 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IFHFLOFL_00750 2.2e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IFHFLOFL_00751 1.9e-269 cydA 1.10.3.14 C ubiquinol oxidase
IFHFLOFL_00752 0.0 macB_3 V ABC transporter, ATP-binding protein
IFHFLOFL_00753 1.5e-195 S DUF218 domain
IFHFLOFL_00754 6.5e-103 S CAAX protease self-immunity
IFHFLOFL_00755 2.2e-93 S Protein of unknown function (DUF1440)
IFHFLOFL_00756 4.5e-269 G PTS system Galactitol-specific IIC component
IFHFLOFL_00757 2.7e-234 G PTS system sugar-specific permease component
IFHFLOFL_00758 2.3e-114 S Protein of unknown function (DUF969)
IFHFLOFL_00759 3.8e-157 S Protein of unknown function (DUF979)
IFHFLOFL_00760 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IFHFLOFL_00761 2.1e-30
IFHFLOFL_00762 4.1e-31
IFHFLOFL_00763 6.2e-28
IFHFLOFL_00764 8.5e-159 mutR K Helix-turn-helix XRE-family like proteins
IFHFLOFL_00765 2.7e-280 V ABC transporter transmembrane region
IFHFLOFL_00767 3.5e-200 napA P Sodium/hydrogen exchanger family
IFHFLOFL_00768 0.0 cadA P P-type ATPase
IFHFLOFL_00769 1.9e-83 ykuL S (CBS) domain
IFHFLOFL_00770 5.9e-19
IFHFLOFL_00771 5.9e-40
IFHFLOFL_00772 4.6e-31
IFHFLOFL_00774 7.1e-56
IFHFLOFL_00776 1.8e-196 ywhK S Membrane
IFHFLOFL_00777 4.4e-43
IFHFLOFL_00779 4.3e-283 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFHFLOFL_00780 1.4e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
IFHFLOFL_00781 3.9e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFHFLOFL_00782 9.3e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IFHFLOFL_00783 1.7e-173 pbpX2 V Beta-lactamase
IFHFLOFL_00784 2e-214 lmrP E Major Facilitator Superfamily
IFHFLOFL_00785 2.1e-38
IFHFLOFL_00786 2.6e-239 pts13C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFHFLOFL_00787 1.1e-156 S Alpha/beta hydrolase of unknown function (DUF915)
IFHFLOFL_00788 0.0 clpE2 O AAA domain (Cdc48 subfamily)
IFHFLOFL_00789 9.7e-245 yfnA E Amino Acid
IFHFLOFL_00790 7.2e-68
IFHFLOFL_00791 1.6e-64 S Domain of unknown function DUF1828
IFHFLOFL_00792 7.4e-88 S Rib/alpha-like repeat
IFHFLOFL_00793 2.9e-246 yagE E amino acid
IFHFLOFL_00794 5.1e-116 GM NmrA-like family
IFHFLOFL_00795 1.9e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
IFHFLOFL_00796 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
IFHFLOFL_00797 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IFHFLOFL_00798 3.9e-240 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IFHFLOFL_00799 0.0 oatA I Acyltransferase
IFHFLOFL_00800 1.4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IFHFLOFL_00801 9.3e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IFHFLOFL_00802 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
IFHFLOFL_00803 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IFHFLOFL_00804 8.1e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IFHFLOFL_00805 2.1e-28 S Protein of unknown function (DUF2929)
IFHFLOFL_00806 0.0 dnaE 2.7.7.7 L DNA polymerase
IFHFLOFL_00808 2.7e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IFHFLOFL_00809 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IFHFLOFL_00810 1.5e-166 cvfB S S1 domain
IFHFLOFL_00811 2.5e-169 xerD D recombinase XerD
IFHFLOFL_00812 3.1e-62 ribT K acetyltransferase
IFHFLOFL_00813 1.1e-135 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IFHFLOFL_00814 2.9e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IFHFLOFL_00815 1.8e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IFHFLOFL_00816 1.9e-58 M Lysin motif
IFHFLOFL_00817 3.8e-97 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IFHFLOFL_00818 1.4e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IFHFLOFL_00819 2.3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
IFHFLOFL_00820 9.4e-242 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IFHFLOFL_00821 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IFHFLOFL_00822 1.1e-231 S Tetratricopeptide repeat protein
IFHFLOFL_00823 1.3e-111 L PFAM Integrase catalytic
IFHFLOFL_00825 2.2e-102 3.6.1.27 I Acid phosphatase homologues
IFHFLOFL_00826 8.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IFHFLOFL_00827 3.7e-18 S Sugar efflux transporter for intercellular exchange
IFHFLOFL_00828 3.4e-310 ybiT S ABC transporter, ATP-binding protein
IFHFLOFL_00829 2.7e-41 K Helix-turn-helix domain
IFHFLOFL_00830 2.8e-146 F DNA/RNA non-specific endonuclease
IFHFLOFL_00831 7.6e-60 L nuclease
IFHFLOFL_00832 1.8e-156 metQ1 P Belongs to the nlpA lipoprotein family
IFHFLOFL_00833 1.6e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IFHFLOFL_00834 2.8e-67 metI P ABC transporter permease
IFHFLOFL_00835 3.8e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IFHFLOFL_00836 2.1e-260 frdC 1.3.5.4 C FAD binding domain
IFHFLOFL_00837 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IFHFLOFL_00838 2.2e-257 yjjP S Putative threonine/serine exporter
IFHFLOFL_00839 2.5e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
IFHFLOFL_00840 0.0 aha1 P E1-E2 ATPase
IFHFLOFL_00841 0.0 S Bacterial membrane protein, YfhO
IFHFLOFL_00842 3e-87 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IFHFLOFL_00843 2.3e-173 prmA J Ribosomal protein L11 methyltransferase
IFHFLOFL_00844 1.4e-65
IFHFLOFL_00845 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IFHFLOFL_00846 7.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IFHFLOFL_00847 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
IFHFLOFL_00848 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IFHFLOFL_00849 3.1e-73
IFHFLOFL_00850 1.5e-82 mutT 3.6.1.55 F NUDIX domain
IFHFLOFL_00851 5.8e-35
IFHFLOFL_00856 4.8e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IFHFLOFL_00857 3.2e-259 qacA EGP Major facilitator Superfamily
IFHFLOFL_00858 2.5e-80 3.6.1.27 I Acid phosphatase homologues
IFHFLOFL_00859 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IFHFLOFL_00860 3.9e-301 ytgP S Polysaccharide biosynthesis protein
IFHFLOFL_00861 8.5e-215 I Protein of unknown function (DUF2974)
IFHFLOFL_00862 8.8e-120
IFHFLOFL_00863 4.3e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IFHFLOFL_00864 2.4e-124 M ErfK YbiS YcfS YnhG
IFHFLOFL_00865 1.7e-63 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IFHFLOFL_00866 4.6e-91 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IFHFLOFL_00867 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IFHFLOFL_00868 7.2e-172 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IFHFLOFL_00869 2.4e-50
IFHFLOFL_00870 9e-77 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
IFHFLOFL_00871 1.5e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IFHFLOFL_00873 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IFHFLOFL_00874 2.7e-128 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
IFHFLOFL_00875 3.9e-108 ylbE GM NAD(P)H-binding
IFHFLOFL_00876 6.9e-83 yebR 1.8.4.14 T GAF domain-containing protein
IFHFLOFL_00877 4.2e-194 S Bacteriocin helveticin-J
IFHFLOFL_00878 2.1e-105 tag 3.2.2.20 L glycosylase
IFHFLOFL_00879 6.9e-162 mleP3 S Membrane transport protein
IFHFLOFL_00880 2.3e-134 S CAAX amino terminal protease
IFHFLOFL_00881 1.4e-144 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IFHFLOFL_00882 6.4e-255 emrY EGP Major facilitator Superfamily
IFHFLOFL_00883 4.5e-261 emrY EGP Major facilitator Superfamily
IFHFLOFL_00884 7.6e-94 yxdD K Bacterial regulatory proteins, tetR family
IFHFLOFL_00885 0.0 4.2.1.53 S Myosin-crossreactive antigen
IFHFLOFL_00886 1.5e-76 2.3.1.128 K acetyltransferase
IFHFLOFL_00887 3.4e-37
IFHFLOFL_00888 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
IFHFLOFL_00889 2.3e-289 scrB 3.2.1.26 GH32 G invertase
IFHFLOFL_00890 1e-184 scrR K Transcriptional regulator, LacI family
IFHFLOFL_00891 4.4e-53 G polysaccharide catabolic process
IFHFLOFL_00892 3.4e-59 G PTS system mannose/fructose/sorbose family IID component
IFHFLOFL_00893 1.7e-36 G PTS system sorbose-specific iic component
IFHFLOFL_00894 9.3e-33 2.7.1.191 G PTS system sorbose subfamily IIB component
IFHFLOFL_00895 7.1e-21 2.7.1.191 G PTS system fructose IIA component
IFHFLOFL_00896 8.3e-194 K Sigma-54 interaction domain
IFHFLOFL_00897 1.2e-36 rpoN K Sigma-54 factor, core binding domain
IFHFLOFL_00898 9.1e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
IFHFLOFL_00899 3.5e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IFHFLOFL_00900 8.6e-130 cobQ S glutamine amidotransferase
IFHFLOFL_00901 1.8e-251 yfnA E Amino Acid
IFHFLOFL_00902 1.2e-161 EG EamA-like transporter family
IFHFLOFL_00903 4e-192 asnA 6.3.1.1 F aspartate--ammonia ligase
IFHFLOFL_00904 7.5e-193 S CAAX protease self-immunity
IFHFLOFL_00905 8.2e-236 steT_1 E amino acid
IFHFLOFL_00906 2.8e-134 puuD S peptidase C26
IFHFLOFL_00907 9e-219 yifK E Amino acid permease
IFHFLOFL_00908 1.3e-249 yifK E Amino acid permease
IFHFLOFL_00909 1.8e-65 manO S Domain of unknown function (DUF956)
IFHFLOFL_00910 5.6e-172 manN G system, mannose fructose sorbose family IID component
IFHFLOFL_00911 1.1e-123 manY G PTS system
IFHFLOFL_00912 2.6e-183 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IFHFLOFL_00914 9.5e-119 ybhL S Belongs to the BI1 family
IFHFLOFL_00915 5.5e-104 4.1.1.45 S Amidohydrolase
IFHFLOFL_00916 1.5e-33 4.1.1.45 S Amidohydrolase
IFHFLOFL_00917 6.8e-245 yrvN L AAA C-terminal domain
IFHFLOFL_00918 7.3e-58 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IFHFLOFL_00919 1.3e-53 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IFHFLOFL_00920 2.5e-86 XK27_09675 K Acetyltransferase (GNAT) domain
IFHFLOFL_00921 7.9e-69 ogt 2.1.1.63 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
IFHFLOFL_00922 6.2e-76 K Transcriptional regulator
IFHFLOFL_00923 5.5e-50 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
IFHFLOFL_00924 6.9e-80 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
IFHFLOFL_00925 2.1e-96 K Acetyltransferase (GNAT) family
IFHFLOFL_00926 1.5e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IFHFLOFL_00927 1.4e-93 dps P Belongs to the Dps family
IFHFLOFL_00928 7.4e-35 copZ C Heavy-metal-associated domain
IFHFLOFL_00929 1.3e-21 cylB V ABC-2 type transporter
IFHFLOFL_00930 2.4e-68 S pyridoxamine 5-phosphate
IFHFLOFL_00931 3.1e-77 yobV1 K WYL domain
IFHFLOFL_00932 1.3e-70 yobV1 K WYL domain
IFHFLOFL_00933 4.1e-30 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IFHFLOFL_00934 2.3e-63 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IFHFLOFL_00935 4.1e-264 npr 1.11.1.1 C NADH oxidase
IFHFLOFL_00936 1.9e-32 G Major facilitator Superfamily
IFHFLOFL_00937 4.9e-61 S Sulfite exporter TauE/SafE
IFHFLOFL_00938 1.2e-89 mdt(A) EGP Major facilitator Superfamily
IFHFLOFL_00939 7.2e-88 mdt(A) EGP Major facilitator Superfamily
IFHFLOFL_00940 2.1e-117 GM NAD(P)H-binding
IFHFLOFL_00941 1.7e-231 E Alpha/beta hydrolase of unknown function (DUF1100)
IFHFLOFL_00942 9.2e-101 K Transcriptional regulator C-terminal region
IFHFLOFL_00944 3.8e-156 C Aldo keto reductase
IFHFLOFL_00945 3.9e-126 lmrA 3.6.3.44 V ABC transporter
IFHFLOFL_00946 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IFHFLOFL_00947 1.7e-32 mta K helix_turn_helix, mercury resistance
IFHFLOFL_00948 4.4e-35 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
IFHFLOFL_00949 1.4e-189 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IFHFLOFL_00950 1.2e-41 yphH S Cupin domain
IFHFLOFL_00951 0.0 S Bacterial membrane protein, YfhO
IFHFLOFL_00952 0.0 pepO 3.4.24.71 O Peptidase family M13
IFHFLOFL_00953 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IFHFLOFL_00954 1.1e-164 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
IFHFLOFL_00955 2e-135 rpl K Helix-turn-helix domain, rpiR family
IFHFLOFL_00956 4.1e-173 D nuclear chromosome segregation
IFHFLOFL_00957 6.6e-187 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
IFHFLOFL_00958 4.2e-228 yttB EGP Major facilitator Superfamily
IFHFLOFL_00959 0.0 UW LPXTG-motif cell wall anchor domain protein
IFHFLOFL_00960 0.0 UW LPXTG-motif cell wall anchor domain protein
IFHFLOFL_00961 1.4e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IFHFLOFL_00962 1.1e-101 J Acetyltransferase (GNAT) domain
IFHFLOFL_00963 1.5e-106 yjbF S SNARE associated Golgi protein
IFHFLOFL_00964 3.5e-151 I alpha/beta hydrolase fold
IFHFLOFL_00965 5.8e-144 hipB K Helix-turn-helix
IFHFLOFL_00966 7.2e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IFHFLOFL_00967 5.1e-179
IFHFLOFL_00968 2.1e-123 S SNARE associated Golgi protein
IFHFLOFL_00969 3.4e-133 cof S haloacid dehalogenase-like hydrolase
IFHFLOFL_00970 1.3e-283 ydgH S MMPL family
IFHFLOFL_00971 5.6e-133 ydgH S MMPL family
IFHFLOFL_00972 3.2e-98 yobS K Bacterial regulatory proteins, tetR family
IFHFLOFL_00973 1.4e-167 3.5.2.6 V Beta-lactamase enzyme family
IFHFLOFL_00974 5.4e-167 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
IFHFLOFL_00975 1.4e-80 yjcF S Acetyltransferase (GNAT) domain
IFHFLOFL_00976 6e-97 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IFHFLOFL_00977 1.1e-77 yybA 2.3.1.57 K Transcriptional regulator
IFHFLOFL_00978 8.7e-52 ypaA S Protein of unknown function (DUF1304)
IFHFLOFL_00979 3e-240 G Bacterial extracellular solute-binding protein
IFHFLOFL_00980 7.9e-257 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
IFHFLOFL_00981 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
IFHFLOFL_00982 9.5e-158 gtsB P ABC-type sugar transport systems, permease components
IFHFLOFL_00983 7.9e-202 malK P ATPases associated with a variety of cellular activities
IFHFLOFL_00984 4.3e-280 pipD E Dipeptidase
IFHFLOFL_00985 2.2e-122 endA F DNA RNA non-specific endonuclease
IFHFLOFL_00986 2.9e-148 dkg S reductase
IFHFLOFL_00987 9.3e-102 ltrA S Bacterial low temperature requirement A protein (LtrA)
IFHFLOFL_00988 2.7e-296 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IFHFLOFL_00989 8.9e-192 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IFHFLOFL_00990 4.2e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IFHFLOFL_00991 0.0 S membrane
IFHFLOFL_00992 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IFHFLOFL_00993 2.4e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IFHFLOFL_00994 9.9e-61 yabR J S1 RNA binding domain
IFHFLOFL_00995 2.3e-60 divIC D Septum formation initiator
IFHFLOFL_00996 1.8e-34 yabO J S4 domain protein
IFHFLOFL_00997 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IFHFLOFL_00998 3.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IFHFLOFL_00999 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IFHFLOFL_01000 2.4e-124 S (CBS) domain
IFHFLOFL_01001 1.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IFHFLOFL_01002 5.9e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IFHFLOFL_01003 7.7e-261 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IFHFLOFL_01004 2.9e-262 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IFHFLOFL_01005 8e-41 rpmE2 J Ribosomal protein L31
IFHFLOFL_01006 3.2e-284 ybeC E amino acid
IFHFLOFL_01007 6.9e-136 XK27_08845 S ABC transporter, ATP-binding protein
IFHFLOFL_01008 4.9e-141 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IFHFLOFL_01009 3e-187 ABC-SBP S ABC transporter
IFHFLOFL_01010 7.1e-132 S Protein of unknown function (DUF975)
IFHFLOFL_01011 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IFHFLOFL_01012 1.1e-153 yitS S EDD domain protein, DegV family
IFHFLOFL_01013 2.2e-19
IFHFLOFL_01014 0.0 tetP J elongation factor G
IFHFLOFL_01015 8.7e-63 P CorA-like Mg2+ transporter protein
IFHFLOFL_01016 1.2e-70 P CorA-like Mg2+ transporter protein
IFHFLOFL_01018 2.5e-40 S Transglycosylase associated protein
IFHFLOFL_01019 5.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
IFHFLOFL_01020 0.0 L Helicase C-terminal domain protein
IFHFLOFL_01021 2.2e-165 S Alpha beta hydrolase
IFHFLOFL_01022 1.8e-40
IFHFLOFL_01023 3.3e-165 K AI-2E family transporter
IFHFLOFL_01024 1e-251 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
IFHFLOFL_01025 6.2e-213 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IFHFLOFL_01026 1.8e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
IFHFLOFL_01027 5.3e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IFHFLOFL_01028 0.0 S domain, Protein
IFHFLOFL_01029 2.8e-113 S domain, Protein
IFHFLOFL_01030 4.9e-204 xerS L Belongs to the 'phage' integrase family
IFHFLOFL_01031 6.7e-167 K Transcriptional regulator
IFHFLOFL_01032 3.7e-151
IFHFLOFL_01033 3.8e-162 degV S EDD domain protein, DegV family
IFHFLOFL_01034 3.8e-64
IFHFLOFL_01035 0.0 FbpA K Fibronectin-binding protein
IFHFLOFL_01036 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
IFHFLOFL_01037 2.8e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IFHFLOFL_01038 1.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IFHFLOFL_01039 2.3e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IFHFLOFL_01040 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IFHFLOFL_01041 9.9e-58
IFHFLOFL_01042 2.2e-173 degV S DegV family
IFHFLOFL_01043 2.3e-223 cpdA S Calcineurin-like phosphoesterase
IFHFLOFL_01044 2.4e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IFHFLOFL_01045 2e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IFHFLOFL_01047 1.5e-24 S PFAM Archaeal ATPase
IFHFLOFL_01048 2.1e-241 pyrP F Permease
IFHFLOFL_01049 3.7e-137 lacR K DeoR C terminal sensor domain
IFHFLOFL_01050 9.4e-74 lacA 5.3.1.26 G Ribose/Galactose Isomerase
IFHFLOFL_01051 1.9e-106 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
IFHFLOFL_01052 1.6e-128 S Domain of unknown function (DUF4867)
IFHFLOFL_01053 7.2e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IFHFLOFL_01054 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
IFHFLOFL_01055 1.4e-267 gatC G PTS system sugar-specific permease component
IFHFLOFL_01056 1.3e-38
IFHFLOFL_01057 1e-148 lacT K CAT RNA binding domain
IFHFLOFL_01058 8.7e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
IFHFLOFL_01059 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
IFHFLOFL_01060 4.8e-292 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IFHFLOFL_01061 1e-201 S PFAM Archaeal ATPase
IFHFLOFL_01062 8.2e-165 K LysR family
IFHFLOFL_01063 0.0 1.3.5.4 C FMN_bind
IFHFLOFL_01064 8.3e-260 P Sodium:sulfate symporter transmembrane region
IFHFLOFL_01065 5.7e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
IFHFLOFL_01066 3.3e-112 3.6.1.27 I Acid phosphatase homologues
IFHFLOFL_01067 1.9e-217 mdtG EGP Major facilitator Superfamily
IFHFLOFL_01068 1.5e-32
IFHFLOFL_01069 6.1e-73 K helix_turn_helix multiple antibiotic resistance protein
IFHFLOFL_01070 5.8e-82
IFHFLOFL_01071 2.7e-210 pepA E M42 glutamyl aminopeptidase
IFHFLOFL_01073 5.9e-88 2.7.1.191 G PTS system sorbose subfamily IIB component
IFHFLOFL_01074 1.2e-103 G PTS system sorbose-specific iic component
IFHFLOFL_01075 3.4e-152 G PTS system mannose/fructose/sorbose family IID component
IFHFLOFL_01076 6.8e-72 2.7.1.191 G PTS system fructose IIA component
IFHFLOFL_01077 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IFHFLOFL_01078 8.2e-182 lacI3 K helix_turn _helix lactose operon repressor
IFHFLOFL_01079 4.4e-224 3.2.1.177 GH31 G Glycosyl hydrolases family 31
IFHFLOFL_01080 1e-169 3.2.1.177 GH31 G Glycosyl hydrolases family 31
IFHFLOFL_01081 1.6e-266 dtpT U amino acid peptide transporter
IFHFLOFL_01082 2.9e-208 naiP EGP Major facilitator Superfamily
IFHFLOFL_01083 3.8e-79 S Alpha beta hydrolase
IFHFLOFL_01084 1.8e-64 S Alpha beta hydrolase
IFHFLOFL_01085 4.6e-76 K Transcriptional regulator, MarR family
IFHFLOFL_01086 2.1e-52 XK27_09600 V ABC transporter, ATP-binding protein
IFHFLOFL_01087 7.1e-248 XK27_09600 V ABC transporter, ATP-binding protein
IFHFLOFL_01088 0.0 V ABC transporter transmembrane region
IFHFLOFL_01089 1.3e-148 glnH ET ABC transporter
IFHFLOFL_01090 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IFHFLOFL_01091 9.1e-150 glnH ET ABC transporter
IFHFLOFL_01092 7.8e-109 gluC P ABC transporter permease
IFHFLOFL_01093 2e-107 glnP P ABC transporter permease
IFHFLOFL_01094 4.8e-151 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_01095 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
IFHFLOFL_01096 1.1e-130 treR K UTRA
IFHFLOFL_01097 0.0 treB 2.7.1.211 G phosphotransferase system
IFHFLOFL_01098 8.3e-84 S Putative adhesin
IFHFLOFL_01099 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
IFHFLOFL_01100 1.9e-205 EGP Major facilitator superfamily
IFHFLOFL_01102 1.6e-35 S Enterocin A Immunity
IFHFLOFL_01103 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
IFHFLOFL_01104 5.7e-160 rssA S Phospholipase, patatin family
IFHFLOFL_01105 3.1e-257 glnPH2 P ABC transporter permease
IFHFLOFL_01106 1.7e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IFHFLOFL_01107 6.2e-96 K Acetyltransferase (GNAT) domain
IFHFLOFL_01108 1.3e-159 pstS P Phosphate
IFHFLOFL_01109 2.1e-161 pstC P probably responsible for the translocation of the substrate across the membrane
IFHFLOFL_01110 8.3e-157 pstA P Phosphate transport system permease protein PstA
IFHFLOFL_01111 4.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IFHFLOFL_01112 2.7e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IFHFLOFL_01113 7.6e-118 phoU P Plays a role in the regulation of phosphate uptake
IFHFLOFL_01114 1.7e-282 S C4-dicarboxylate anaerobic carrier
IFHFLOFL_01115 5.8e-85 dps P Belongs to the Dps family
IFHFLOFL_01117 3.2e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IFHFLOFL_01118 4.8e-128 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IFHFLOFL_01119 4.1e-175 rihB 3.2.2.1 F Nucleoside
IFHFLOFL_01120 4e-133 gntR K UbiC transcription regulator-associated domain protein
IFHFLOFL_01121 2e-52 S Enterocin A Immunity
IFHFLOFL_01122 1.8e-116 glcR K DeoR C terminal sensor domain
IFHFLOFL_01123 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IFHFLOFL_01124 1.6e-120 C nitroreductase
IFHFLOFL_01125 1.1e-132
IFHFLOFL_01126 3.6e-252 yhdP S Transporter associated domain
IFHFLOFL_01127 2.8e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IFHFLOFL_01128 5e-235 potE E amino acid
IFHFLOFL_01129 9.9e-137 M Glycosyl hydrolases family 25
IFHFLOFL_01130 4.1e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
IFHFLOFL_01131 2.1e-249 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFHFLOFL_01134 1.7e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IFHFLOFL_01135 2e-86 gtcA S Teichoic acid glycosylation protein
IFHFLOFL_01136 4.2e-77 fld C Flavodoxin
IFHFLOFL_01137 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
IFHFLOFL_01138 1.6e-166 yihY S Belongs to the UPF0761 family
IFHFLOFL_01139 8.7e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IFHFLOFL_01140 8.8e-153 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_01141 4.4e-180 E ABC transporter, ATP-binding protein
IFHFLOFL_01142 1.6e-288 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IFHFLOFL_01143 6.9e-66 O OsmC-like protein
IFHFLOFL_01144 8.3e-21 ltrA S Bacterial low temperature requirement A protein (LtrA)
IFHFLOFL_01145 1.9e-112 2.7.6.5 T Region found in RelA / SpoT proteins
IFHFLOFL_01146 5.3e-116 K response regulator
IFHFLOFL_01147 1.6e-233 sptS 2.7.13.3 T Histidine kinase
IFHFLOFL_01148 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IFHFLOFL_01149 1e-19
IFHFLOFL_01150 4.2e-50
IFHFLOFL_01151 0.0 pepN 3.4.11.2 E aminopeptidase
IFHFLOFL_01152 2.5e-141 S haloacid dehalogenase-like hydrolase
IFHFLOFL_01153 5.2e-122 S CAAX protease self-immunity
IFHFLOFL_01155 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IFHFLOFL_01156 6.6e-72
IFHFLOFL_01157 2.1e-108 fic D Fic/DOC family
IFHFLOFL_01158 1.8e-225 I transferase activity, transferring acyl groups other than amino-acyl groups
IFHFLOFL_01159 3.5e-128 pnb C nitroreductase
IFHFLOFL_01160 7.1e-98 S Domain of unknown function (DUF4811)
IFHFLOFL_01161 1.8e-265 lmrB EGP Major facilitator Superfamily
IFHFLOFL_01162 1.2e-76 K MerR HTH family regulatory protein
IFHFLOFL_01163 0.0 oppA E ABC transporter substrate-binding protein
IFHFLOFL_01164 5.5e-112 tdk 2.7.1.21 F thymidine kinase
IFHFLOFL_01165 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IFHFLOFL_01166 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IFHFLOFL_01167 1.2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IFHFLOFL_01168 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IFHFLOFL_01169 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
IFHFLOFL_01170 2.1e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IFHFLOFL_01171 5.9e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IFHFLOFL_01172 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IFHFLOFL_01173 5.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IFHFLOFL_01174 3.1e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IFHFLOFL_01175 3.3e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IFHFLOFL_01176 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IFHFLOFL_01177 2e-30 ywzB S Protein of unknown function (DUF1146)
IFHFLOFL_01178 2.2e-179 mbl D Cell shape determining protein MreB Mrl
IFHFLOFL_01179 2.5e-15 S DNA-directed RNA polymerase subunit beta
IFHFLOFL_01180 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IFHFLOFL_01181 1.3e-34 S Protein of unknown function (DUF2969)
IFHFLOFL_01182 3.6e-224 rodA D Belongs to the SEDS family
IFHFLOFL_01183 5.2e-81 usp6 T universal stress protein
IFHFLOFL_01185 7.4e-239 rarA L recombination factor protein RarA
IFHFLOFL_01186 1e-81 yueI S Protein of unknown function (DUF1694)
IFHFLOFL_01187 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IFHFLOFL_01189 1.8e-145 K SIS domain
IFHFLOFL_01190 1.2e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
IFHFLOFL_01193 1.4e-52 P Rhodanese Homology Domain
IFHFLOFL_01194 9.3e-190
IFHFLOFL_01195 9.5e-124 gntR1 K UTRA
IFHFLOFL_01196 1.5e-67 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IFHFLOFL_01197 1.2e-140 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IFHFLOFL_01198 2.9e-204 csaB M Glycosyl transferases group 1
IFHFLOFL_01199 0.0 tuaG GT2 M Glycosyltransferase like family 2
IFHFLOFL_01200 2e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IFHFLOFL_01201 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IFHFLOFL_01202 0.0 pacL 3.6.3.8 P P-type ATPase
IFHFLOFL_01203 1.2e-48 V ABC transporter transmembrane region
IFHFLOFL_01204 0.0 lhr L DEAD DEAH box helicase
IFHFLOFL_01205 5.4e-253 P P-loop Domain of unknown function (DUF2791)
IFHFLOFL_01206 0.0 S TerB-C domain
IFHFLOFL_01207 1.3e-99 4.1.1.44 S decarboxylase
IFHFLOFL_01208 5.1e-72
IFHFLOFL_01209 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IFHFLOFL_01210 2.4e-232 cycA E Amino acid permease
IFHFLOFL_01212 5.4e-09 L Initiator Replication protein
IFHFLOFL_01214 1.3e-95 D CobQ CobB MinD ParA nucleotide binding domain protein
IFHFLOFL_01218 1.3e-07 K sequence-specific DNA binding
IFHFLOFL_01219 3.6e-125 S Fic/DOC family
IFHFLOFL_01220 1.8e-26 2.1.1.72, 3.1.21.3 V restriction
IFHFLOFL_01221 1.8e-122 2.1.1.72, 3.1.21.3 V N-6 DNA Methylase
IFHFLOFL_01223 1.8e-150 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
IFHFLOFL_01224 1.7e-59 yjgN S Bacterial protein of unknown function (DUF898)
IFHFLOFL_01226 3.9e-93 M LysM domain protein
IFHFLOFL_01227 1.3e-110 M LysM domain protein
IFHFLOFL_01228 2.3e-133 S Putative ABC-transporter type IV
IFHFLOFL_01229 5.8e-49 psiE S Phosphate-starvation-inducible E
IFHFLOFL_01230 7.9e-75 K acetyltransferase
IFHFLOFL_01231 2.2e-180 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFHFLOFL_01232 3.9e-196 G Psort location CytoplasmicMembrane, score 10.00
IFHFLOFL_01233 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IFHFLOFL_01234 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IFHFLOFL_01235 8.9e-116 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IFHFLOFL_01236 2.6e-109 lacA 2.3.1.79 S Transferase hexapeptide repeat
IFHFLOFL_01237 1.8e-124 magIII L Base excision DNA repair protein, HhH-GPD family
IFHFLOFL_01238 3.3e-166 akr5f 1.1.1.346 S reductase
IFHFLOFL_01239 1.1e-74 C Aldo/keto reductase family
IFHFLOFL_01240 2.9e-14 C Aldo/keto reductase family
IFHFLOFL_01241 3.3e-77 S Fic/DOC family
IFHFLOFL_01242 1.7e-103 S Uncharacterised protein family (UPF0236)
IFHFLOFL_01243 3.5e-13 fhaB M Rib/alpha-like repeat
IFHFLOFL_01244 4.2e-238 fhaB M Rib/alpha-like repeat
IFHFLOFL_01245 5e-60
IFHFLOFL_01257 4.2e-217 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
IFHFLOFL_01258 3.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
IFHFLOFL_01259 4.5e-183 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IFHFLOFL_01260 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IFHFLOFL_01261 2.2e-189 yhjX P Major Facilitator Superfamily
IFHFLOFL_01262 6.9e-83 I Carboxylesterase family
IFHFLOFL_01263 2.7e-63 I Carboxylesterase family
IFHFLOFL_01264 3.6e-165 rhaS6 K helix_turn_helix, arabinose operon control protein
IFHFLOFL_01265 4.7e-168 2.7.1.2 GK ROK family
IFHFLOFL_01266 4.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
IFHFLOFL_01267 7.8e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
IFHFLOFL_01286 6.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IFHFLOFL_01287 4.8e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IFHFLOFL_01288 4.1e-130 ymfC K UTRA
IFHFLOFL_01289 8.2e-254 3.5.1.18 E Peptidase family M20/M25/M40
IFHFLOFL_01290 1.3e-179 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
IFHFLOFL_01291 2.9e-93 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
IFHFLOFL_01292 4.6e-196 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFHFLOFL_01293 1.2e-117 cutC P Participates in the control of copper homeostasis
IFHFLOFL_01294 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IFHFLOFL_01295 1.4e-75 K UTRA
IFHFLOFL_01296 5.9e-12
IFHFLOFL_01297 1.5e-50 rmaI K Transcriptional regulator
IFHFLOFL_01298 2e-210 EGP Major facilitator Superfamily
IFHFLOFL_01299 5.7e-230 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
IFHFLOFL_01300 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IFHFLOFL_01301 1.3e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IFHFLOFL_01302 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IFHFLOFL_01303 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IFHFLOFL_01304 2.3e-251 dnaB L Replication initiation and membrane attachment
IFHFLOFL_01305 2.7e-163 dnaI L Primosomal protein DnaI
IFHFLOFL_01306 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IFHFLOFL_01307 1.4e-72 K LytTr DNA-binding domain
IFHFLOFL_01308 1.9e-74 S Protein of unknown function (DUF3021)
IFHFLOFL_01309 4.8e-171 V ABC transporter
IFHFLOFL_01310 1.3e-131 S domain protein
IFHFLOFL_01311 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IFHFLOFL_01312 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IFHFLOFL_01313 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IFHFLOFL_01314 9.8e-191 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IFHFLOFL_01315 3.5e-91 yqeG S HAD phosphatase, family IIIA
IFHFLOFL_01316 4.7e-210 yqeH S Ribosome biogenesis GTPase YqeH
IFHFLOFL_01317 4.4e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IFHFLOFL_01318 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IFHFLOFL_01319 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IFHFLOFL_01320 2.2e-218 ylbM S Belongs to the UPF0348 family
IFHFLOFL_01321 2.9e-96 yceD S Uncharacterized ACR, COG1399
IFHFLOFL_01322 1.1e-130 K response regulator
IFHFLOFL_01323 1.9e-281 arlS 2.7.13.3 T Histidine kinase
IFHFLOFL_01324 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IFHFLOFL_01325 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IFHFLOFL_01326 9.6e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IFHFLOFL_01327 7.3e-64 yodB K Transcriptional regulator, HxlR family
IFHFLOFL_01328 8.1e-204 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IFHFLOFL_01329 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IFHFLOFL_01330 2.9e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IFHFLOFL_01331 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IFHFLOFL_01332 0.0 S membrane
IFHFLOFL_01333 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IFHFLOFL_01334 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IFHFLOFL_01335 5.6e-87 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IFHFLOFL_01336 2e-118 gluP 3.4.21.105 S Rhomboid family
IFHFLOFL_01337 6e-35 yqgQ S Bacterial protein of unknown function (DUF910)
IFHFLOFL_01338 1.5e-57 yqhL P Rhodanese-like protein
IFHFLOFL_01339 1.1e-18 S Protein of unknown function (DUF3042)
IFHFLOFL_01340 9.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IFHFLOFL_01341 1.1e-261 glnA 6.3.1.2 E glutamine synthetase
IFHFLOFL_01342 1.1e-204 EGP Major facilitator Superfamily
IFHFLOFL_01343 4.3e-152 S haloacid dehalogenase-like hydrolase
IFHFLOFL_01344 2.4e-07
IFHFLOFL_01345 8.1e-179 D Alpha beta
IFHFLOFL_01346 6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
IFHFLOFL_01347 3.9e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IFHFLOFL_01348 2.9e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IFHFLOFL_01349 9.2e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IFHFLOFL_01350 7.8e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
IFHFLOFL_01351 2.4e-112 ygaC J Belongs to the UPF0374 family
IFHFLOFL_01352 4.9e-90
IFHFLOFL_01353 3e-78
IFHFLOFL_01354 1.6e-157 hlyX S Transporter associated domain
IFHFLOFL_01355 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IFHFLOFL_01356 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
IFHFLOFL_01357 0.0 clpE O Belongs to the ClpA ClpB family
IFHFLOFL_01358 6.9e-26
IFHFLOFL_01359 1.2e-39 ptsH G phosphocarrier protein HPR
IFHFLOFL_01360 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IFHFLOFL_01361 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IFHFLOFL_01362 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IFHFLOFL_01363 1.7e-162 coiA 3.6.4.12 S Competence protein
IFHFLOFL_01364 7e-107 yjbH Q Thioredoxin
IFHFLOFL_01365 3.3e-112 yjbK S CYTH
IFHFLOFL_01366 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
IFHFLOFL_01367 5.2e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IFHFLOFL_01368 3.7e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IFHFLOFL_01369 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
IFHFLOFL_01370 3.9e-234 N Uncharacterized conserved protein (DUF2075)
IFHFLOFL_01371 4.8e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IFHFLOFL_01372 9.9e-67 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IFHFLOFL_01373 5.4e-212 yubA S AI-2E family transporter
IFHFLOFL_01374 2.7e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IFHFLOFL_01375 4.6e-76 WQ51_03320 S Protein of unknown function (DUF1149)
IFHFLOFL_01376 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IFHFLOFL_01377 7.2e-228 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
IFHFLOFL_01378 8.3e-232 S Peptidase M16
IFHFLOFL_01379 1.6e-129 IQ Enoyl-(Acyl carrier protein) reductase
IFHFLOFL_01380 4.3e-125 ymfM S Helix-turn-helix domain
IFHFLOFL_01381 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IFHFLOFL_01382 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IFHFLOFL_01383 1.2e-209 rny S Endoribonuclease that initiates mRNA decay
IFHFLOFL_01384 2.7e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
IFHFLOFL_01385 2.5e-118 yvyE 3.4.13.9 S YigZ family
IFHFLOFL_01386 1.6e-241 comFA L Helicase C-terminal domain protein
IFHFLOFL_01387 5.7e-126 comFC S Competence protein
IFHFLOFL_01388 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IFHFLOFL_01389 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IFHFLOFL_01390 6.2e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IFHFLOFL_01391 2.5e-35
IFHFLOFL_01392 3.8e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IFHFLOFL_01393 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IFHFLOFL_01394 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IFHFLOFL_01395 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IFHFLOFL_01396 7.6e-52 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
IFHFLOFL_01397 5.8e-155
IFHFLOFL_01398 2.8e-224 mdtG EGP Major facilitator Superfamily
IFHFLOFL_01399 1.9e-121 puuD S peptidase C26
IFHFLOFL_01400 1e-290 V ABC transporter transmembrane region
IFHFLOFL_01401 5.7e-86 ymdB S Macro domain protein
IFHFLOFL_01402 7.2e-124 yoaK S Protein of unknown function (DUF1275)
IFHFLOFL_01403 7.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IFHFLOFL_01404 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IFHFLOFL_01405 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
IFHFLOFL_01406 2.2e-179 K Transcriptional regulator
IFHFLOFL_01407 1.4e-228 XK27_04775 S PAS domain
IFHFLOFL_01408 6.4e-105 S Iron-sulfur cluster assembly protein
IFHFLOFL_01409 5.3e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IFHFLOFL_01410 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IFHFLOFL_01411 1.2e-64
IFHFLOFL_01412 5.6e-75 S Fic/DOC family
IFHFLOFL_01413 3.8e-70 Z012_06740 S Fic/DOC family
IFHFLOFL_01414 1.6e-62 L COG1961 Site-specific recombinases, DNA invertase Pin homologs
IFHFLOFL_01415 6.6e-57 higA K Helix-turn-helix XRE-family like proteins
IFHFLOFL_01416 5.7e-17 IQ reductase
IFHFLOFL_01417 8.1e-249 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IFHFLOFL_01418 2e-163 yvgN C Aldo keto reductase
IFHFLOFL_01420 4.8e-131 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_01421 1e-19 licT K transcriptional antiterminator
IFHFLOFL_01422 1.2e-26 licT K CAT RNA binding domain
IFHFLOFL_01423 7e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IFHFLOFL_01424 0.0 rafA 3.2.1.22 G alpha-galactosidase
IFHFLOFL_01425 2.1e-83
IFHFLOFL_01426 1.4e-122 KL domain protein
IFHFLOFL_01427 1.7e-75 KL domain protein
IFHFLOFL_01428 4.3e-195 KL domain protein
IFHFLOFL_01431 7.2e-197 ampC V Beta-lactamase
IFHFLOFL_01432 4.9e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
IFHFLOFL_01433 4.1e-147 S hydrolase
IFHFLOFL_01434 3.2e-103 yagU S Protein of unknown function (DUF1440)
IFHFLOFL_01435 1.2e-143 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IFHFLOFL_01436 6.3e-63 pipD E Dipeptidase
IFHFLOFL_01437 6.3e-122 pipD E Dipeptidase
IFHFLOFL_01438 3.1e-119 K Helix-turn-helix XRE-family like proteins
IFHFLOFL_01439 2e-227 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IFHFLOFL_01440 3.3e-52 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IFHFLOFL_01441 1.2e-48 L bacterial-type proximal promoter sequence-specific DNA binding
IFHFLOFL_01442 1.2e-74 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
IFHFLOFL_01443 5.4e-122 L oxidized base lesion DNA N-glycosylase activity
IFHFLOFL_01444 6e-13
IFHFLOFL_01445 1.7e-243 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IFHFLOFL_01446 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IFHFLOFL_01447 1.8e-120 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IFHFLOFL_01448 5.5e-49 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IFHFLOFL_01449 3.4e-97 S Protein of unknown function (DUF3990)
IFHFLOFL_01450 4.3e-46
IFHFLOFL_01451 7.5e-242 clcA P chloride
IFHFLOFL_01452 7.2e-107
IFHFLOFL_01453 6.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IFHFLOFL_01454 1.3e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IFHFLOFL_01455 2.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IFHFLOFL_01456 5.8e-86 folT S ECF transporter, substrate-specific component
IFHFLOFL_01457 3.3e-127 fat 3.1.2.21 I Acyl-ACP thioesterase
IFHFLOFL_01458 8.2e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IFHFLOFL_01459 4.9e-57 yabA L Involved in initiation control of chromosome replication
IFHFLOFL_01460 1.5e-150 holB 2.7.7.7 L DNA polymerase III
IFHFLOFL_01461 1e-51 yaaQ S Cyclic-di-AMP receptor
IFHFLOFL_01462 1.6e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IFHFLOFL_01463 5.3e-26 S Protein of unknown function (DUF2508)
IFHFLOFL_01464 1.8e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IFHFLOFL_01465 1.7e-51 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IFHFLOFL_01466 5.5e-309 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IFHFLOFL_01467 8.4e-81 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IFHFLOFL_01468 1.9e-23
IFHFLOFL_01469 3.9e-113 rsmC 2.1.1.172 J Methyltransferase
IFHFLOFL_01470 5.3e-31
IFHFLOFL_01471 2e-94 L hmm pf00665
IFHFLOFL_01472 3.4e-67 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IFHFLOFL_01473 4.3e-40 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IFHFLOFL_01474 4.5e-199 G PTS system sugar-specific permease component
IFHFLOFL_01475 2.6e-35 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IFHFLOFL_01476 5.6e-73 S Uncharacterised protein family UPF0047
IFHFLOFL_01477 1.4e-62 kdsD 5.3.1.13 M SIS domain
IFHFLOFL_01478 1.3e-40 5.3.1.27 M SIS domain
IFHFLOFL_01479 3.2e-163 2.7.1.202 GKT Mga helix-turn-helix domain
IFHFLOFL_01481 2.1e-68 L PFAM transposase, IS4 family protein
IFHFLOFL_01482 3.1e-70 L PFAM transposase, IS4 family protein
IFHFLOFL_01483 8.2e-149 kcsA P Ion transport protein
IFHFLOFL_01484 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IFHFLOFL_01485 3.1e-96 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IFHFLOFL_01486 2.9e-145 aatB ET ABC transporter substrate-binding protein
IFHFLOFL_01487 4.4e-115 glnQ 3.6.3.21 E ABC transporter
IFHFLOFL_01488 2.5e-107 glnP P ABC transporter permease
IFHFLOFL_01489 1.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IFHFLOFL_01490 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IFHFLOFL_01491 5.8e-100 nusG K Participates in transcription elongation, termination and antitermination
IFHFLOFL_01492 9.1e-12 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IFHFLOFL_01493 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IFHFLOFL_01494 1.4e-189 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IFHFLOFL_01495 6.9e-226 G Major Facilitator Superfamily
IFHFLOFL_01496 1.9e-239 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IFHFLOFL_01497 2.4e-81 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IFHFLOFL_01498 3.7e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IFHFLOFL_01499 2.7e-285 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IFHFLOFL_01500 1.7e-34
IFHFLOFL_01501 4.6e-97 yvrI K sigma factor activity
IFHFLOFL_01502 2.3e-286 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IFHFLOFL_01503 2.3e-288 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
IFHFLOFL_01504 1.9e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
IFHFLOFL_01505 1.3e-151 lacT K PRD domain
IFHFLOFL_01506 1.2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IFHFLOFL_01507 3.8e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IFHFLOFL_01508 1.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IFHFLOFL_01509 9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IFHFLOFL_01510 9.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IFHFLOFL_01511 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IFHFLOFL_01512 1.8e-256 pepC 3.4.22.40 E Peptidase C1-like family
IFHFLOFL_01513 2.9e-184 S AAA domain
IFHFLOFL_01514 5.2e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IFHFLOFL_01515 1.6e-25
IFHFLOFL_01516 4.4e-42
IFHFLOFL_01517 3.4e-155 czcD P cation diffusion facilitator family transporter
IFHFLOFL_01518 2.6e-52 K Transcriptional regulator, ArsR family
IFHFLOFL_01519 9.6e-129 pgm3 G Belongs to the phosphoglycerate mutase family
IFHFLOFL_01520 3.8e-110 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
IFHFLOFL_01521 3.5e-160 1.6.5.2 GM NmrA-like family
IFHFLOFL_01522 1.2e-79
IFHFLOFL_01523 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IFHFLOFL_01524 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IFHFLOFL_01525 3.5e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IFHFLOFL_01526 3.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFHFLOFL_01527 7e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFHFLOFL_01528 5.1e-156 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFHFLOFL_01529 1.3e-61 rplQ J Ribosomal protein L17
IFHFLOFL_01530 1.3e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFHFLOFL_01531 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IFHFLOFL_01532 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IFHFLOFL_01533 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IFHFLOFL_01534 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IFHFLOFL_01535 5.9e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IFHFLOFL_01536 2.2e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IFHFLOFL_01537 1.3e-70 rplO J Binds to the 23S rRNA
IFHFLOFL_01538 1.4e-23 rpmD J Ribosomal protein L30
IFHFLOFL_01539 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IFHFLOFL_01540 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IFHFLOFL_01541 5e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IFHFLOFL_01542 2.7e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IFHFLOFL_01543 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IFHFLOFL_01544 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IFHFLOFL_01545 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IFHFLOFL_01546 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IFHFLOFL_01547 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IFHFLOFL_01548 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IFHFLOFL_01549 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IFHFLOFL_01550 3.9e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IFHFLOFL_01551 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IFHFLOFL_01552 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IFHFLOFL_01553 1.4e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IFHFLOFL_01554 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IFHFLOFL_01555 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
IFHFLOFL_01556 2.2e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IFHFLOFL_01557 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IFHFLOFL_01558 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IFHFLOFL_01559 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IFHFLOFL_01560 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IFHFLOFL_01561 2.4e-108 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IFHFLOFL_01562 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFHFLOFL_01563 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFHFLOFL_01564 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IFHFLOFL_01566 1.6e-08
IFHFLOFL_01568 1.5e-35 relB L RelB antitoxin
IFHFLOFL_01569 2.1e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IFHFLOFL_01570 5.3e-228 L Transposase
IFHFLOFL_01571 7.2e-158 L COG2963 Transposase and inactivated derivatives
IFHFLOFL_01572 6.6e-150 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IFHFLOFL_01576 2.1e-138 rpiR1 K Helix-turn-helix domain, rpiR family
IFHFLOFL_01577 2.4e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IFHFLOFL_01578 0.0 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
IFHFLOFL_01579 1.4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
IFHFLOFL_01580 2.4e-51
IFHFLOFL_01581 7.6e-24
IFHFLOFL_01582 5.3e-68 pgm3 G Phosphoglycerate mutase family
IFHFLOFL_01583 1.5e-40 pgm3 G Phosphoglycerate mutase family
IFHFLOFL_01584 0.0 V FtsX-like permease family
IFHFLOFL_01585 3.5e-132 cysA V ABC transporter, ATP-binding protein
IFHFLOFL_01586 4.7e-279 E amino acid
IFHFLOFL_01587 3.5e-121 V ABC-2 type transporter
IFHFLOFL_01588 8.4e-123 V Transport permease protein
IFHFLOFL_01589 4.5e-135 V ABC transporter
IFHFLOFL_01590 5.7e-26
IFHFLOFL_01591 1.5e-32
IFHFLOFL_01593 7.3e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IFHFLOFL_01594 2.5e-225 S Putative peptidoglycan binding domain
IFHFLOFL_01595 9.5e-102 M NlpC P60 family protein
IFHFLOFL_01596 2.7e-97 gmk2 2.7.4.8 F Guanylate kinase
IFHFLOFL_01597 9e-44
IFHFLOFL_01598 1.2e-264 S O-antigen ligase like membrane protein
IFHFLOFL_01599 1.3e-108
IFHFLOFL_01600 2.7e-79 nrdI F NrdI Flavodoxin like
IFHFLOFL_01601 1e-171 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IFHFLOFL_01602 2.1e-77
IFHFLOFL_01603 6.8e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IFHFLOFL_01604 3.1e-40
IFHFLOFL_01605 1.3e-79 S Threonine/Serine exporter, ThrE
IFHFLOFL_01606 1.1e-136 thrE S Putative threonine/serine exporter
IFHFLOFL_01607 3.4e-283 S ABC transporter, ATP-binding protein
IFHFLOFL_01608 3.5e-59
IFHFLOFL_01609 4.4e-37
IFHFLOFL_01610 7.4e-211 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IFHFLOFL_01611 0.0 pepF E oligoendopeptidase F
IFHFLOFL_01612 2e-70 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_01613 1.8e-249 lctP C L-lactate permease
IFHFLOFL_01614 2.2e-129 znuB U ABC 3 transport family
IFHFLOFL_01615 4.4e-115 fhuC P ABC transporter
IFHFLOFL_01616 4.4e-150 psaA P Belongs to the bacterial solute-binding protein 9 family
IFHFLOFL_01617 1.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
IFHFLOFL_01618 2.3e-134 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
IFHFLOFL_01619 0.0 M domain protein
IFHFLOFL_01620 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
IFHFLOFL_01621 3.4e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IFHFLOFL_01622 8.4e-134 fruR K DeoR C terminal sensor domain
IFHFLOFL_01623 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IFHFLOFL_01624 3.3e-204 natB CP ABC-2 family transporter protein
IFHFLOFL_01625 1.8e-159 natA S ABC transporter, ATP-binding protein
IFHFLOFL_01626 9.7e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IFHFLOFL_01627 1.1e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IFHFLOFL_01628 6.4e-202 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
IFHFLOFL_01629 7.4e-121 K response regulator
IFHFLOFL_01630 0.0 V ABC transporter
IFHFLOFL_01631 6.8e-41 V ABC transporter, ATP-binding protein
IFHFLOFL_01632 1.1e-219 V ABC transporter, ATP-binding protein
IFHFLOFL_01633 1.1e-121 XK27_01040 S Protein of unknown function (DUF1129)
IFHFLOFL_01634 5.7e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IFHFLOFL_01635 1.1e-42 yyzM S Bacterial protein of unknown function (DUF951)
IFHFLOFL_01636 2.2e-154 spo0J K Belongs to the ParB family
IFHFLOFL_01637 3.3e-138 soj D Sporulation initiation inhibitor
IFHFLOFL_01638 1.4e-140 noc K Belongs to the ParB family
IFHFLOFL_01639 4.4e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IFHFLOFL_01640 4.1e-95 cvpA S Colicin V production protein
IFHFLOFL_01641 2e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IFHFLOFL_01642 1.2e-146 3.1.3.48 T Tyrosine phosphatase family
IFHFLOFL_01643 1.4e-192 4.2.1.126 S Bacterial protein of unknown function (DUF871)
IFHFLOFL_01644 7.1e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
IFHFLOFL_01645 1.5e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
IFHFLOFL_01646 2.9e-108 K WHG domain
IFHFLOFL_01647 1e-37
IFHFLOFL_01648 3.2e-264 pipD E Dipeptidase
IFHFLOFL_01649 1.2e-293 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFHFLOFL_01650 2.1e-295 2.7.1.211 G phosphotransferase system
IFHFLOFL_01651 1.2e-157 K CAT RNA binding domain
IFHFLOFL_01652 6.2e-112 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IFHFLOFL_01653 1.7e-169 hrtB V ABC transporter permease
IFHFLOFL_01654 5.6e-89 ygfC K Bacterial regulatory proteins, tetR family
IFHFLOFL_01655 1.1e-107 G phosphoglycerate mutase
IFHFLOFL_01656 1.7e-111 G Phosphoglycerate mutase family
IFHFLOFL_01657 5.2e-136 aroD S Alpha/beta hydrolase family
IFHFLOFL_01658 2.6e-101 S Protein of unknown function (DUF975)
IFHFLOFL_01659 1.4e-128 S Belongs to the UPF0246 family
IFHFLOFL_01660 2.2e-52
IFHFLOFL_01661 1.6e-123
IFHFLOFL_01662 9.2e-156 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IFHFLOFL_01663 2.7e-308 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
IFHFLOFL_01664 7.3e-138 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
IFHFLOFL_01665 4.1e-153 ybbH_2 K Helix-turn-helix domain, rpiR family
IFHFLOFL_01666 2.3e-147 2.7.7.12 C Domain of unknown function (DUF4931)
IFHFLOFL_01667 1e-16 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_01668 3.4e-42 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IFHFLOFL_01669 1.7e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IFHFLOFL_01670 8.7e-226 ecsB U ABC transporter
IFHFLOFL_01671 2.4e-133 ecsA V ABC transporter, ATP-binding protein
IFHFLOFL_01672 2.4e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
IFHFLOFL_01673 2e-64
IFHFLOFL_01674 4.4e-37 S YtxH-like protein
IFHFLOFL_01675 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IFHFLOFL_01676 1.6e-185 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
IFHFLOFL_01677 0.0 L AAA domain
IFHFLOFL_01678 1.6e-230 yhaO L Ser Thr phosphatase family protein
IFHFLOFL_01679 3.3e-56 yheA S Belongs to the UPF0342 family
IFHFLOFL_01680 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IFHFLOFL_01681 1.8e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IFHFLOFL_01683 1.3e-259 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
IFHFLOFL_01684 1.3e-66
IFHFLOFL_01685 2e-94 3.6.1.55 L NUDIX domain
IFHFLOFL_01686 2.2e-153 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
IFHFLOFL_01687 3.9e-198 V Beta-lactamase
IFHFLOFL_01688 8.4e-63
IFHFLOFL_01689 0.0 L helicase activity
IFHFLOFL_01690 6.4e-227 K DNA binding
IFHFLOFL_01691 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
IFHFLOFL_01692 1.8e-127 mod 2.1.1.72, 3.1.21.5 L DNA methylase
IFHFLOFL_01693 1.5e-115 mod 2.1.1.72, 3.1.21.5 L DNA methylase
IFHFLOFL_01694 7.4e-39 K Cro/C1-type HTH DNA-binding domain
IFHFLOFL_01695 1.1e-77
IFHFLOFL_01696 6.2e-208
IFHFLOFL_01697 3.2e-36
IFHFLOFL_01698 7.4e-233
IFHFLOFL_01700 2.7e-23
IFHFLOFL_01701 3.4e-12
IFHFLOFL_01702 1.6e-221 L Protein of unknown function (DUF2800)
IFHFLOFL_01703 1.7e-99 S Protein of unknown function (DUF2815)
IFHFLOFL_01704 0.0 polA_2 2.7.7.7 L DNA polymerase
IFHFLOFL_01705 2.8e-69 S Psort location Cytoplasmic, score
IFHFLOFL_01706 0.0 S Phage plasmid primase, P4
IFHFLOFL_01707 2.4e-46 S VRR_NUC
IFHFLOFL_01708 1.3e-257 L SNF2 family N-terminal domain
IFHFLOFL_01709 2.8e-87
IFHFLOFL_01710 1.4e-36
IFHFLOFL_01711 2.2e-245 2.1.1.72 KL DNA methylase
IFHFLOFL_01712 2.3e-113 S Psort location Cytoplasmic, score
IFHFLOFL_01713 6.2e-31 S Domain of unknown function (DUF5049)
IFHFLOFL_01714 2.1e-299 S overlaps another CDS with the same product name
IFHFLOFL_01715 2.5e-247 S Phage portal protein
IFHFLOFL_01716 2.9e-122 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
IFHFLOFL_01717 6.3e-221 S Phage capsid family
IFHFLOFL_01718 4.3e-43 S Phage gp6-like head-tail connector protein
IFHFLOFL_01719 9e-68 S Phage head-tail joining protein
IFHFLOFL_01720 3e-69 S Bacteriophage holin family
IFHFLOFL_01721 2.5e-145 M Glycosyl hydrolases family 25
IFHFLOFL_01722 4.3e-36
IFHFLOFL_01723 3.1e-164 L Recombinase zinc beta ribbon domain
IFHFLOFL_01724 7.7e-100 L Recombinase zinc beta ribbon domain
IFHFLOFL_01725 3.8e-290 L Recombinase
IFHFLOFL_01726 2.7e-227
IFHFLOFL_01727 8.7e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IFHFLOFL_01728 9.6e-121 spaE S ABC-2 family transporter protein
IFHFLOFL_01729 1.6e-108 mutF V ABC transporter, ATP-binding protein
IFHFLOFL_01730 1.3e-241 nhaC C Na H antiporter NhaC
IFHFLOFL_01731 9.6e-163 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
IFHFLOFL_01732 3.3e-95 S UPF0397 protein
IFHFLOFL_01733 0.0 ykoD P ABC transporter, ATP-binding protein
IFHFLOFL_01734 3.1e-142 cbiQ P cobalt transport
IFHFLOFL_01735 2.7e-118 ybhL S Belongs to the BI1 family
IFHFLOFL_01736 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
IFHFLOFL_01737 4.7e-64 S Domain of unknown function (DUF4430)
IFHFLOFL_01738 8.1e-88 S ECF transporter, substrate-specific component
IFHFLOFL_01739 2.1e-94 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
IFHFLOFL_01740 4.4e-129 L Helix-turn-helix domain
IFHFLOFL_01741 2.3e-23 L hmm pf00665
IFHFLOFL_01742 1.2e-39 L hmm pf00665
IFHFLOFL_01743 9.6e-152 S hydrolase
IFHFLOFL_01745 7.3e-169 yegS 2.7.1.107 G Lipid kinase
IFHFLOFL_01746 1.5e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IFHFLOFL_01747 1.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IFHFLOFL_01748 4.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IFHFLOFL_01749 1.7e-207 camS S sex pheromone
IFHFLOFL_01750 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IFHFLOFL_01751 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IFHFLOFL_01752 1.8e-113 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
IFHFLOFL_01753 1.3e-100 S ECF transporter, substrate-specific component
IFHFLOFL_01755 7.4e-85 ydcK S Belongs to the SprT family
IFHFLOFL_01756 7e-135 M Glycosyltransferase sugar-binding region containing DXD motif
IFHFLOFL_01757 1.9e-256 epsU S Polysaccharide biosynthesis protein
IFHFLOFL_01758 4.7e-229 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IFHFLOFL_01759 3.7e-219 V ABC transporter transmembrane region
IFHFLOFL_01760 0.0 comEC S Competence protein ComEC
IFHFLOFL_01761 1.2e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
IFHFLOFL_01762 1.3e-33 rpsT J Binds directly to 16S ribosomal RNA
IFHFLOFL_01763 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IFHFLOFL_01764 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IFHFLOFL_01765 7.7e-160
IFHFLOFL_01766 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IFHFLOFL_01767 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IFHFLOFL_01768 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IFHFLOFL_01769 1.2e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
IFHFLOFL_01770 6.7e-89 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IFHFLOFL_01771 7.4e-78
IFHFLOFL_01772 1.2e-70 S Domain of unknown function (DUF4767)
IFHFLOFL_01773 2.2e-224
IFHFLOFL_01774 2.5e-121 frnE Q DSBA-like thioredoxin domain
IFHFLOFL_01775 9.6e-180 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IFHFLOFL_01777 4.9e-75 S HIRAN
IFHFLOFL_01779 7.2e-164 htpX O Peptidase family M48
IFHFLOFL_01780 7e-32
IFHFLOFL_01781 1.4e-223 patA 2.6.1.1 E Aminotransferase
IFHFLOFL_01782 6.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IFHFLOFL_01783 2.4e-144 E GDSL-like Lipase/Acylhydrolase family
IFHFLOFL_01784 3.8e-107 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IFHFLOFL_01785 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IFHFLOFL_01786 1e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IFHFLOFL_01787 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IFHFLOFL_01788 4.1e-40 yqeY S YqeY-like protein
IFHFLOFL_01789 4e-173 phoH T phosphate starvation-inducible protein PhoH
IFHFLOFL_01790 1.2e-91 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IFHFLOFL_01791 1.3e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IFHFLOFL_01792 1.6e-137 recO L Involved in DNA repair and RecF pathway recombination
IFHFLOFL_01793 1.8e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IFHFLOFL_01794 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IFHFLOFL_01795 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IFHFLOFL_01796 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IFHFLOFL_01797 2.5e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
IFHFLOFL_01798 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IFHFLOFL_01799 1.6e-246 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IFHFLOFL_01800 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
IFHFLOFL_01801 3.3e-124 skfE V ATPases associated with a variety of cellular activities
IFHFLOFL_01802 2.1e-138
IFHFLOFL_01803 2.3e-108
IFHFLOFL_01804 8.1e-22
IFHFLOFL_01805 1e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IFHFLOFL_01806 4e-133
IFHFLOFL_01807 1.1e-167
IFHFLOFL_01808 1.5e-229 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
IFHFLOFL_01809 3.5e-52 ybjQ S Belongs to the UPF0145 family
IFHFLOFL_01810 1.1e-160 XK27_05540 S DUF218 domain
IFHFLOFL_01811 5.1e-153 yxeH S hydrolase
IFHFLOFL_01812 2.3e-303 I Protein of unknown function (DUF2974)
IFHFLOFL_01813 2.7e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IFHFLOFL_01814 1.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IFHFLOFL_01815 6.8e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IFHFLOFL_01816 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IFHFLOFL_01817 2.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IFHFLOFL_01818 2.8e-32 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IFHFLOFL_01819 3.1e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IFHFLOFL_01820 1.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IFHFLOFL_01821 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IFHFLOFL_01822 3.3e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IFHFLOFL_01823 3.6e-27 pncA Q Isochorismatase family
IFHFLOFL_01824 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IFHFLOFL_01825 5.7e-126 alkD L DNA alkylation repair enzyme
IFHFLOFL_01827 2.9e-128 XK27_06785 V ABC transporter, ATP-binding protein
IFHFLOFL_01828 0.0 XK27_06780 V ABC transporter permease
IFHFLOFL_01829 0.0 pepO 3.4.24.71 O Peptidase family M13
IFHFLOFL_01830 4.8e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
IFHFLOFL_01831 2.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IFHFLOFL_01832 3.3e-283 thrC 4.2.3.1 E Threonine synthase
IFHFLOFL_01833 2.7e-230 hom1 1.1.1.3 E homoserine dehydrogenase
IFHFLOFL_01834 3.3e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IFHFLOFL_01835 1.1e-167 lysR7 K LysR substrate binding domain
IFHFLOFL_01836 0.0 1.3.5.4 C FMN_bind
IFHFLOFL_01837 8.4e-119 drgA C nitroreductase
IFHFLOFL_01838 2.8e-28
IFHFLOFL_01839 8.7e-23
IFHFLOFL_01840 6.5e-10
IFHFLOFL_01841 1.4e-72
IFHFLOFL_01842 2e-205 EGP Major facilitator Superfamily
IFHFLOFL_01843 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
IFHFLOFL_01844 1.4e-107 vanZ V VanZ like family
IFHFLOFL_01845 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IFHFLOFL_01846 5.3e-270 T PhoQ Sensor
IFHFLOFL_01847 9e-130 K Transcriptional regulatory protein, C terminal
IFHFLOFL_01848 9.2e-68 S SdpI/YhfL protein family
IFHFLOFL_01849 2.9e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
IFHFLOFL_01850 1.8e-80 patB 4.4.1.8 E Aminotransferase, class I
IFHFLOFL_01851 1e-76 M Protein of unknown function (DUF3737)
IFHFLOFL_01852 2.1e-226 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
IFHFLOFL_01853 1.8e-47 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
IFHFLOFL_01854 1.4e-132 sip L Belongs to the 'phage' integrase family
IFHFLOFL_01855 7.3e-13 S sequence-specific DNA binding
IFHFLOFL_01856 4.8e-20
IFHFLOFL_01858 1.5e-10
IFHFLOFL_01860 2.9e-28
IFHFLOFL_01861 1.9e-35 S Primase C terminal 1 (PriCT-1)
IFHFLOFL_01862 1.4e-84 S DNA primase
IFHFLOFL_01865 5e-09
IFHFLOFL_01867 3.6e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IFHFLOFL_01868 1.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
IFHFLOFL_01869 4.7e-88 comGF U Putative Competence protein ComGF
IFHFLOFL_01871 7e-66
IFHFLOFL_01872 1.1e-36 comGC U Required for transformation and DNA binding
IFHFLOFL_01873 4.7e-177 comGB NU type II secretion system
IFHFLOFL_01874 5.8e-180 comGA NU Type II IV secretion system protein
IFHFLOFL_01875 1.5e-132 yebC K Transcriptional regulatory protein
IFHFLOFL_01876 7.3e-97 S VanZ like family
IFHFLOFL_01877 3.7e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IFHFLOFL_01878 4.5e-163 znuA P Belongs to the bacterial solute-binding protein 9 family
IFHFLOFL_01879 8.5e-150 yisY 1.11.1.10 S Alpha/beta hydrolase family
IFHFLOFL_01880 4.8e-115
IFHFLOFL_01881 3.1e-178 S Putative adhesin
IFHFLOFL_01882 5.3e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IFHFLOFL_01883 2.3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IFHFLOFL_01884 3.8e-148 S Sucrose-6F-phosphate phosphohydrolase
IFHFLOFL_01885 2.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IFHFLOFL_01886 8.1e-174 ybbR S YbbR-like protein
IFHFLOFL_01887 3.4e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IFHFLOFL_01888 1.3e-209 potD P ABC transporter
IFHFLOFL_01889 8.5e-137 potC P ABC transporter permease
IFHFLOFL_01890 2.7e-130 potB P ABC transporter permease
IFHFLOFL_01891 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IFHFLOFL_01892 4.4e-166 murB 1.3.1.98 M Cell wall formation
IFHFLOFL_01893 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
IFHFLOFL_01894 1.3e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IFHFLOFL_01895 2.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IFHFLOFL_01896 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IFHFLOFL_01897 8e-157 ycsE S Sucrose-6F-phosphate phosphohydrolase
IFHFLOFL_01898 2.9e-93
IFHFLOFL_01899 6.6e-91
IFHFLOFL_01901 1e-107 3.2.2.20 K acetyltransferase
IFHFLOFL_01902 2.3e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IFHFLOFL_01903 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IFHFLOFL_01904 2.5e-28 secG U Preprotein translocase
IFHFLOFL_01905 1.2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IFHFLOFL_01906 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IFHFLOFL_01907 6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IFHFLOFL_01908 1.6e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IFHFLOFL_01909 2.3e-187 cggR K Putative sugar-binding domain
IFHFLOFL_01911 1.2e-277 ycaM E amino acid
IFHFLOFL_01912 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IFHFLOFL_01913 6.2e-171 whiA K May be required for sporulation
IFHFLOFL_01914 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IFHFLOFL_01915 6e-160 rapZ S Displays ATPase and GTPase activities
IFHFLOFL_01916 1.1e-90 S Short repeat of unknown function (DUF308)
IFHFLOFL_01917 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IFHFLOFL_01918 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IFHFLOFL_01919 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IFHFLOFL_01920 1.6e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IFHFLOFL_01921 5.2e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IFHFLOFL_01922 1.4e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IFHFLOFL_01923 9.2e-181 lacR K Transcriptional regulator

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)