ORF_ID e_value Gene_name EC_number CAZy COGs Description
EKEPFMFD_00001 0.0 uvrA2 L ABC transporter
EKEPFMFD_00002 1.6e-15 L transposase and inactivated derivatives, IS30 family
EKEPFMFD_00007 1.7e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EKEPFMFD_00008 6.1e-117 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EKEPFMFD_00009 4.2e-167 whiA K May be required for sporulation
EKEPFMFD_00010 1.1e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EKEPFMFD_00011 8.6e-159 rapZ S Displays ATPase and GTPase activities
EKEPFMFD_00012 2.8e-70
EKEPFMFD_00013 1.1e-116
EKEPFMFD_00014 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EKEPFMFD_00015 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EKEPFMFD_00017 1.4e-113 yfbR S HD containing hydrolase-like enzyme
EKEPFMFD_00018 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EKEPFMFD_00019 1.6e-135 cof S haloacid dehalogenase-like hydrolase
EKEPFMFD_00020 1.7e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EKEPFMFD_00021 2.5e-197 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EKEPFMFD_00022 4.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EKEPFMFD_00023 6.2e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EKEPFMFD_00024 9.7e-132 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EKEPFMFD_00025 2.8e-40 yphH S Cupin domain
EKEPFMFD_00026 3.1e-10 yphH S Cupin domain
EKEPFMFD_00027 1.2e-185 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKEPFMFD_00028 4.8e-15 mtnE 2.6.1.83 E Aminotransferase
EKEPFMFD_00029 8.4e-199 mtnE 2.6.1.83 E Aminotransferase
EKEPFMFD_00030 5.7e-146 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
EKEPFMFD_00031 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EKEPFMFD_00032 1.2e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EKEPFMFD_00033 1.4e-161 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EKEPFMFD_00034 2.7e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EKEPFMFD_00035 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
EKEPFMFD_00036 4.1e-53 KT PspC domain protein
EKEPFMFD_00037 2.9e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EKEPFMFD_00038 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EKEPFMFD_00039 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EKEPFMFD_00040 1e-127 comFC S Competence protein
EKEPFMFD_00041 1.9e-250 comFA L Helicase C-terminal domain protein
EKEPFMFD_00042 3.2e-110 yvyE 3.4.13.9 S YigZ family
EKEPFMFD_00043 4.2e-37
EKEPFMFD_00044 0.0 ydaO E amino acid
EKEPFMFD_00045 2.6e-289 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EKEPFMFD_00046 1.6e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EKEPFMFD_00047 9.7e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EKEPFMFD_00048 0.0 uup S ABC transporter, ATP-binding protein
EKEPFMFD_00049 1.2e-169 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EKEPFMFD_00050 1.8e-90 bioY S BioY family
EKEPFMFD_00051 4.1e-111 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EKEPFMFD_00052 2e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
EKEPFMFD_00053 5.1e-90 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EKEPFMFD_00054 3.9e-60 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EKEPFMFD_00055 4.6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
EKEPFMFD_00056 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EKEPFMFD_00057 7.8e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EKEPFMFD_00058 5e-229 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EKEPFMFD_00059 2.7e-129 IQ reductase
EKEPFMFD_00060 3e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EKEPFMFD_00061 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKEPFMFD_00062 4.4e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKEPFMFD_00063 5.7e-74 marR K Transcriptional regulator, MarR family
EKEPFMFD_00064 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EKEPFMFD_00066 1.7e-193 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EKEPFMFD_00067 4.3e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
EKEPFMFD_00068 2.1e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
EKEPFMFD_00069 1.3e-212 arcT 2.6.1.1 E Aminotransferase
EKEPFMFD_00070 4e-217 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
EKEPFMFD_00071 2.8e-227 E Arginine ornithine antiporter
EKEPFMFD_00072 2.9e-10 E Arginine ornithine antiporter
EKEPFMFD_00073 9.1e-239 arcA 3.5.3.6 E Arginine
EKEPFMFD_00074 3.5e-166 arcC 2.7.2.2 E Belongs to the carbamate kinase family
EKEPFMFD_00075 8.6e-187 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EKEPFMFD_00076 3.7e-146 KT YcbB domain
EKEPFMFD_00077 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EKEPFMFD_00078 6.9e-140 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EKEPFMFD_00079 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EKEPFMFD_00080 1.5e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EKEPFMFD_00081 2.5e-138 fat 3.1.2.21 I Acyl-ACP thioesterase
EKEPFMFD_00082 3e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EKEPFMFD_00083 3.4e-55 yabA L Involved in initiation control of chromosome replication
EKEPFMFD_00084 1.3e-190 holB 2.7.7.7 L DNA polymerase III
EKEPFMFD_00085 1.2e-52 yaaQ S Cyclic-di-AMP receptor
EKEPFMFD_00086 5.7e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EKEPFMFD_00087 2.4e-21 S Protein of unknown function (DUF2508)
EKEPFMFD_00088 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EKEPFMFD_00089 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EKEPFMFD_00090 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKEPFMFD_00092 1.7e-72 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EKEPFMFD_00093 2e-35 nrdH O Glutaredoxin
EKEPFMFD_00094 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKEPFMFD_00095 4.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKEPFMFD_00096 9.7e-125 IQ reductase
EKEPFMFD_00097 4.6e-87 lacR K Transcriptional regulator
EKEPFMFD_00098 7.5e-208 lacS G Transporter
EKEPFMFD_00099 2.6e-251 lacZ 3.2.1.23 G -beta-galactosidase
EKEPFMFD_00100 8.1e-244 brnQ U Component of the transport system for branched-chain amino acids
EKEPFMFD_00101 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EKEPFMFD_00102 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EKEPFMFD_00103 2.9e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EKEPFMFD_00104 5.3e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
EKEPFMFD_00105 8.1e-271 cydA 1.10.3.14 C ubiquinol oxidase
EKEPFMFD_00106 5.9e-51 K TRANSCRIPTIONal
EKEPFMFD_00107 2.9e-262 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKEPFMFD_00108 3e-173 yegS 2.7.1.107 G Lipid kinase
EKEPFMFD_00109 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKEPFMFD_00110 1.3e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EKEPFMFD_00111 6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKEPFMFD_00112 1.8e-164 camS S sex pheromone
EKEPFMFD_00113 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EKEPFMFD_00114 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EKEPFMFD_00115 2.5e-217 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EKEPFMFD_00116 8e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EKEPFMFD_00117 2.9e-108 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
EKEPFMFD_00118 1.7e-137 IQ reductase
EKEPFMFD_00119 4.7e-186 S interspecies interaction between organisms
EKEPFMFD_00120 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
EKEPFMFD_00121 7.7e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EKEPFMFD_00122 5.9e-143 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EKEPFMFD_00123 1.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKEPFMFD_00124 7e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKEPFMFD_00125 1.5e-147 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKEPFMFD_00126 3.1e-60 rplQ J Ribosomal protein L17
EKEPFMFD_00127 4.5e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKEPFMFD_00128 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EKEPFMFD_00129 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EKEPFMFD_00130 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EKEPFMFD_00131 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EKEPFMFD_00132 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EKEPFMFD_00133 3.4e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EKEPFMFD_00134 2.1e-65 rplO J Binds to the 23S rRNA
EKEPFMFD_00135 2.5e-23 rpmD J Ribosomal protein L30
EKEPFMFD_00136 9.7e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EKEPFMFD_00137 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EKEPFMFD_00138 4.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EKEPFMFD_00139 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EKEPFMFD_00140 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKEPFMFD_00141 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EKEPFMFD_00142 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EKEPFMFD_00143 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EKEPFMFD_00144 4e-29 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EKEPFMFD_00145 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
EKEPFMFD_00146 3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EKEPFMFD_00147 3.5e-104 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EKEPFMFD_00148 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EKEPFMFD_00149 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EKEPFMFD_00150 6e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EKEPFMFD_00151 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EKEPFMFD_00152 2e-104 rplD J Forms part of the polypeptide exit tunnel
EKEPFMFD_00153 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EKEPFMFD_00154 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EKEPFMFD_00155 7e-65 yviA S Protein of unknown function (DUF421)
EKEPFMFD_00156 1.9e-29 S Protein of unknown function (DUF3290)
EKEPFMFD_00157 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKEPFMFD_00158 3.6e-58 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EKEPFMFD_00159 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EKEPFMFD_00160 9.6e-33 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
EKEPFMFD_00161 1.2e-211 ykiI
EKEPFMFD_00162 1.2e-134 puuD S peptidase C26
EKEPFMFD_00163 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKEPFMFD_00164 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKEPFMFD_00165 1.4e-104 K Bacterial regulatory proteins, tetR family
EKEPFMFD_00166 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EKEPFMFD_00167 4.8e-79 ctsR K Belongs to the CtsR family
EKEPFMFD_00168 5.5e-272 sufB O assembly protein SufB
EKEPFMFD_00169 7.9e-82 nifU C SUF system FeS assembly protein, NifU family
EKEPFMFD_00170 7.3e-228 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKEPFMFD_00171 1.4e-234 sufD O FeS assembly protein SufD
EKEPFMFD_00172 2.5e-144 sufC O FeS assembly ATPase SufC
EKEPFMFD_00173 3.9e-33 feoA P FeoA domain
EKEPFMFD_00174 1.2e-49 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EKEPFMFD_00175 2.5e-300 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EKEPFMFD_00176 8.7e-23 S Virus attachment protein p12 family
EKEPFMFD_00177 6.6e-154 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
EKEPFMFD_00178 4.8e-174 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EKEPFMFD_00179 1.2e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKEPFMFD_00180 5.1e-215 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
EKEPFMFD_00181 1.9e-89 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EKEPFMFD_00182 2.5e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EKEPFMFD_00183 4.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EKEPFMFD_00184 7.2e-103
EKEPFMFD_00185 4e-212 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EKEPFMFD_00186 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
EKEPFMFD_00187 3.9e-210 ydiN G Major Facilitator Superfamily
EKEPFMFD_00188 6e-25 dtpT U amino acid peptide transporter
EKEPFMFD_00189 1.1e-213 dtpT U amino acid peptide transporter
EKEPFMFD_00191 4e-150 S Sucrose-6F-phosphate phosphohydrolase
EKEPFMFD_00192 8e-48 1.6.5.2 GM NAD(P)H-binding
EKEPFMFD_00193 5.5e-89 1.6.5.2 GM NAD(P)H-binding
EKEPFMFD_00194 1.7e-154 S Alpha beta hydrolase
EKEPFMFD_00195 1.9e-235 lmrB EGP Major facilitator Superfamily
EKEPFMFD_00197 0.0 S Bacterial membrane protein YfhO
EKEPFMFD_00198 4.6e-13
EKEPFMFD_00199 8.1e-46
EKEPFMFD_00200 0.0 kup P Transport of potassium into the cell
EKEPFMFD_00202 7.4e-283 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EKEPFMFD_00203 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EKEPFMFD_00204 0.0 yjbQ P TrkA C-terminal domain protein
EKEPFMFD_00205 1.1e-275 pipD E Dipeptidase
EKEPFMFD_00206 3.8e-149 S Alpha/beta hydrolase of unknown function (DUF915)
EKEPFMFD_00207 4.5e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKEPFMFD_00208 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKEPFMFD_00209 2.2e-167 T Calcineurin-like phosphoesterase superfamily domain
EKEPFMFD_00210 7.6e-111 EGP Major facilitator Superfamily
EKEPFMFD_00211 5.7e-30 EGP Major facilitator Superfamily
EKEPFMFD_00212 1.1e-199 mdtG EGP Major facilitator Superfamily
EKEPFMFD_00213 1.7e-249 yhdP S Transporter associated domain
EKEPFMFD_00214 1.6e-211 naiP EGP Major facilitator Superfamily
EKEPFMFD_00215 3e-23 K LysR substrate binding domain protein
EKEPFMFD_00216 1.4e-34 K LysR substrate binding domain protein
EKEPFMFD_00217 2.1e-213 E GDSL-like Lipase/Acylhydrolase family
EKEPFMFD_00218 1.9e-194 lplA 6.3.1.20 H Lipoate-protein ligase
EKEPFMFD_00219 6.9e-259 lpdA 1.8.1.4 C Dehydrogenase
EKEPFMFD_00220 4.2e-202 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKEPFMFD_00221 2.9e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
EKEPFMFD_00222 5.3e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EKEPFMFD_00223 2.2e-24 K DNA-binding helix-turn-helix protein
EKEPFMFD_00224 3.4e-20 K Transcriptional regulator
EKEPFMFD_00226 8.2e-10 K Transcriptional regulator
EKEPFMFD_00227 1.2e-29 1.14.12.17 S Cupin 2, conserved barrel domain protein
EKEPFMFD_00228 3.8e-78 ubiE Q Mycolic acid cyclopropane synthetase
EKEPFMFD_00229 5.4e-90 deoR K sugar-binding domain protein
EKEPFMFD_00230 3.6e-115 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
EKEPFMFD_00231 2.1e-161 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
EKEPFMFD_00232 2.4e-196 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EKEPFMFD_00233 5.5e-89 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EKEPFMFD_00235 1.6e-57 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
EKEPFMFD_00236 9.3e-305 L Type III restriction enzyme, res subunit
EKEPFMFD_00237 5.7e-165 L Type III restriction enzyme, res subunit
EKEPFMFD_00239 1e-99 K DNA-templated transcription, initiation
EKEPFMFD_00240 4.7e-43 IQ reductase
EKEPFMFD_00241 7.5e-240 treB G phosphotransferase system
EKEPFMFD_00242 5e-72 treR K UTRA
EKEPFMFD_00243 1.5e-239 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
EKEPFMFD_00249 6.9e-11 D nuclear chromosome segregation
EKEPFMFD_00250 1.7e-68 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EKEPFMFD_00251 4.6e-52 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKEPFMFD_00252 1.2e-53 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKEPFMFD_00253 1.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKEPFMFD_00254 5.1e-104 wecD3 K Acetyltransferase (GNAT) family
EKEPFMFD_00255 1e-309 ubiB S ABC1 family
EKEPFMFD_00256 8.3e-128 1.14.12.17 C Oxidoreductase NAD-binding domain
EKEPFMFD_00257 2.4e-167 GK ROK family
EKEPFMFD_00258 7.4e-40
EKEPFMFD_00259 9.9e-77 copY K Copper transport repressor CopY TcrY
EKEPFMFD_00261 5.7e-53 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
EKEPFMFD_00263 9e-170 mutR K Transcriptional activator, Rgg GadR MutR family
EKEPFMFD_00264 3.8e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
EKEPFMFD_00265 3.6e-228 gntT EG Gluconate
EKEPFMFD_00266 2.2e-182 K Transcriptional regulator, LacI family
EKEPFMFD_00267 2.8e-60 yneR
EKEPFMFD_00268 9.8e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EKEPFMFD_00269 2.2e-96 V VanZ like family
EKEPFMFD_00270 1.1e-262 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EKEPFMFD_00271 1.8e-57 ydgH S MMPL family
EKEPFMFD_00272 3.1e-52 ywnB S NAD(P)H-binding
EKEPFMFD_00273 1e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EKEPFMFD_00274 5e-134 XK27_01040 S Protein of unknown function (DUF1129)
EKEPFMFD_00275 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EKEPFMFD_00276 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
EKEPFMFD_00277 3e-145 spo0J K Belongs to the ParB family
EKEPFMFD_00278 1.7e-157 noc K Belongs to the ParB family
EKEPFMFD_00279 4.6e-42 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
EKEPFMFD_00280 5.6e-78 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
EKEPFMFD_00281 2.2e-144 rihC 3.2.2.1 F Nucleoside
EKEPFMFD_00282 3.2e-212 nupG F Nucleoside transporter
EKEPFMFD_00283 1.3e-249 cycA E Amino acid permease
EKEPFMFD_00284 1.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EKEPFMFD_00285 4.4e-224 glnP P ABC transporter
EKEPFMFD_00287 2.6e-172 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
EKEPFMFD_00289 1.3e-227 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EKEPFMFD_00290 0.0 sbcC L Putative exonuclease SbcCD, C subunit
EKEPFMFD_00291 1.8e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EKEPFMFD_00293 2.4e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKEPFMFD_00294 7e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
EKEPFMFD_00295 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKEPFMFD_00296 1.4e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EKEPFMFD_00297 1.1e-41 iolS C Aldo keto reductase
EKEPFMFD_00298 2.6e-55 iolS C Aldo keto reductase
EKEPFMFD_00299 2.2e-117 brnQ U Component of the transport system for branched-chain amino acids
EKEPFMFD_00300 2.5e-56 brnQ U Component of the transport system for branched-chain amino acids
EKEPFMFD_00301 4.4e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKEPFMFD_00302 5e-215 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
EKEPFMFD_00303 8.4e-96 metI P ABC transporter permease
EKEPFMFD_00304 2.8e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EKEPFMFD_00305 5.1e-148 metQ1 P Belongs to the nlpA lipoprotein family
EKEPFMFD_00306 8.7e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
EKEPFMFD_00307 6e-272 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
EKEPFMFD_00308 1.5e-46
EKEPFMFD_00309 1.1e-107 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EKEPFMFD_00310 1.2e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EKEPFMFD_00311 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EKEPFMFD_00312 5.4e-256 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
EKEPFMFD_00313 3.9e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EKEPFMFD_00314 7.4e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EKEPFMFD_00315 1.3e-91 K transcriptional regulator
EKEPFMFD_00316 4.4e-124 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
EKEPFMFD_00317 3.3e-179 ybhR V ABC transporter
EKEPFMFD_00318 8.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
EKEPFMFD_00319 5e-288 3.2.1.21 GH3 G hydrolase, family 3
EKEPFMFD_00320 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
EKEPFMFD_00321 0.0 trxB2 1.8.1.9 C Thioredoxin domain
EKEPFMFD_00322 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
EKEPFMFD_00324 3.9e-84 K GNAT family
EKEPFMFD_00325 7e-119 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
EKEPFMFD_00326 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
EKEPFMFD_00327 9.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EKEPFMFD_00328 2e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
EKEPFMFD_00330 1e-56
EKEPFMFD_00332 3.5e-08
EKEPFMFD_00333 1.5e-77 K Winged helix DNA-binding domain
EKEPFMFD_00334 0.0 lmrA V ABC transporter, ATP-binding protein
EKEPFMFD_00335 0.0 yfiC V ABC transporter
EKEPFMFD_00336 2e-191 ampC V Beta-lactamase
EKEPFMFD_00337 1.6e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKEPFMFD_00338 2.7e-46
EKEPFMFD_00339 5.8e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
EKEPFMFD_00340 1.9e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
EKEPFMFD_00341 5.5e-109 tdk 2.7.1.21 F thymidine kinase
EKEPFMFD_00342 1.2e-154 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EKEPFMFD_00343 3.9e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EKEPFMFD_00344 1.4e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EKEPFMFD_00345 7.8e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EKEPFMFD_00346 3.6e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EKEPFMFD_00347 2.3e-180 yibE S overlaps another CDS with the same product name
EKEPFMFD_00348 9.5e-125 yibF S overlaps another CDS with the same product name
EKEPFMFD_00349 5.4e-218 pyrP F Permease
EKEPFMFD_00350 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
EKEPFMFD_00351 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKEPFMFD_00352 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EKEPFMFD_00353 2.2e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKEPFMFD_00354 1.9e-209 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EKEPFMFD_00355 7.4e-65 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EKEPFMFD_00356 3.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EKEPFMFD_00357 3.7e-252 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EKEPFMFD_00358 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EKEPFMFD_00359 2.8e-29 S Protein of unknown function (DUF1146)
EKEPFMFD_00360 1.9e-215 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
EKEPFMFD_00361 2.9e-182 mbl D Cell shape determining protein MreB Mrl
EKEPFMFD_00362 7.9e-32 S Protein of unknown function (DUF2969)
EKEPFMFD_00363 2.4e-220 rodA D Belongs to the SEDS family
EKEPFMFD_00365 2.7e-177 S Protein of unknown function (DUF2785)
EKEPFMFD_00366 1.2e-213 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EKEPFMFD_00367 9.2e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
EKEPFMFD_00368 0.0 comEC S Competence protein ComEC
EKEPFMFD_00369 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
EKEPFMFD_00370 3.8e-90 comEA L Competence protein ComEA
EKEPFMFD_00371 6.7e-193 ylbL T Belongs to the peptidase S16 family
EKEPFMFD_00372 9.6e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EKEPFMFD_00373 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
EKEPFMFD_00374 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
EKEPFMFD_00375 8.7e-210 ftsW D Belongs to the SEDS family
EKEPFMFD_00376 0.0 typA T GTP-binding protein TypA
EKEPFMFD_00377 1.5e-135 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EKEPFMFD_00378 1.2e-48 yktA S Belongs to the UPF0223 family
EKEPFMFD_00379 4.9e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EKEPFMFD_00380 8.4e-14
EKEPFMFD_00381 1.4e-48
EKEPFMFD_00382 2.2e-31 ykzG S Belongs to the UPF0356 family
EKEPFMFD_00383 5.6e-26 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
EKEPFMFD_00384 5.8e-140 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
EKEPFMFD_00385 4.2e-74 spx4 1.20.4.1 P ArsC family
EKEPFMFD_00386 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EKEPFMFD_00387 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EKEPFMFD_00388 6e-123 S Repeat protein
EKEPFMFD_00389 2e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
EKEPFMFD_00390 8.9e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EKEPFMFD_00391 1.6e-304 S amidohydrolase
EKEPFMFD_00392 9.3e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EKEPFMFD_00393 7.6e-58 XK27_04120 S Putative amino acid metabolism
EKEPFMFD_00394 3.3e-74 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EKEPFMFD_00395 6.4e-36 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EKEPFMFD_00397 2.5e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
EKEPFMFD_00398 1.2e-32 cspB K Cold shock protein
EKEPFMFD_00399 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EKEPFMFD_00401 1.2e-99 divIVA D DivIVA domain protein
EKEPFMFD_00402 2.2e-145 ylmH S S4 domain protein
EKEPFMFD_00403 1.2e-40 yggT S YGGT family
EKEPFMFD_00404 2.5e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EKEPFMFD_00405 4.3e-215 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EKEPFMFD_00406 3.7e-85 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EKEPFMFD_00407 3.9e-109 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EKEPFMFD_00408 2.8e-146 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EKEPFMFD_00409 3.4e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKEPFMFD_00410 1.2e-258 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EKEPFMFD_00411 5.4e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKEPFMFD_00412 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
EKEPFMFD_00413 2e-08 ftsL D Cell division protein FtsL
EKEPFMFD_00414 9e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EKEPFMFD_00415 9.6e-79 mraZ K Belongs to the MraZ family
EKEPFMFD_00416 2.8e-205 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EKEPFMFD_00417 1.9e-245 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EKEPFMFD_00418 1.4e-86 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EKEPFMFD_00419 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EKEPFMFD_00420 3.6e-134 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EKEPFMFD_00421 1.9e-28 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EKEPFMFD_00422 5.4e-155 recO L Involved in DNA repair and RecF pathway recombination
EKEPFMFD_00423 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EKEPFMFD_00424 2.3e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EKEPFMFD_00425 2.8e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EKEPFMFD_00426 2.1e-91 phoH T phosphate starvation-inducible protein PhoH
EKEPFMFD_00427 2.1e-77 phoH T phosphate starvation-inducible protein PhoH
EKEPFMFD_00428 2.1e-71 yqeY S YqeY-like protein
EKEPFMFD_00429 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EKEPFMFD_00430 1.8e-127 yfeJ 6.3.5.2 F glutamine amidotransferase
EKEPFMFD_00431 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EKEPFMFD_00432 8.7e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
EKEPFMFD_00433 5.7e-194 6.3.1.20 H Lipoate-protein ligase
EKEPFMFD_00434 6.3e-146 lytH 3.5.1.28 M Ami_3
EKEPFMFD_00435 2.2e-167 yniA G Phosphotransferase enzyme family
EKEPFMFD_00436 8.3e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
EKEPFMFD_00437 1e-241 mmuP E amino acid
EKEPFMFD_00438 1.2e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EKEPFMFD_00439 9.5e-25 hom1 1.1.1.3 E Homoserine dehydrogenase
EKEPFMFD_00440 6.1e-169 hom1 1.1.1.3 E Homoserine dehydrogenase
EKEPFMFD_00441 3.7e-134 IQ KR domain
EKEPFMFD_00442 9.1e-153 cjaA ET ABC transporter substrate-binding protein
EKEPFMFD_00443 1.5e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EKEPFMFD_00444 2e-91 P ABC transporter permease
EKEPFMFD_00445 2.3e-111 papP P ABC transporter, permease protein
EKEPFMFD_00447 1.2e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
EKEPFMFD_00448 1.8e-218 metC1 2.5.1.48, 4.4.1.8 E cystathionine
EKEPFMFD_00449 3.3e-83 slyA K Transcriptional regulator
EKEPFMFD_00450 2.1e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EKEPFMFD_00451 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EKEPFMFD_00452 5.7e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EKEPFMFD_00453 3.2e-178 prmA J Ribosomal protein L11 methyltransferase
EKEPFMFD_00454 8e-54
EKEPFMFD_00456 2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EKEPFMFD_00457 1.4e-92 S integral membrane protein
EKEPFMFD_00458 1.7e-75 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKEPFMFD_00459 1.5e-183 argE 3.5.1.16 E Acetylornithine deacetylase
EKEPFMFD_00460 2.8e-14 S Domain of unknown function DUF1829
EKEPFMFD_00461 4.4e-49 tnp L MULE transposase domain
EKEPFMFD_00462 1.3e-63
EKEPFMFD_00465 1.2e-112 K Transcriptional regulator
EKEPFMFD_00466 1.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
EKEPFMFD_00467 9e-53 ysxB J Cysteine protease Prp
EKEPFMFD_00468 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EKEPFMFD_00469 2.3e-206 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EKEPFMFD_00470 4.1e-72 yqhY S Asp23 family, cell envelope-related function
EKEPFMFD_00471 4.4e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKEPFMFD_00472 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EKEPFMFD_00473 2.5e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EKEPFMFD_00474 2.9e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EKEPFMFD_00475 7.6e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EKEPFMFD_00476 1.9e-48 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EKEPFMFD_00477 1.5e-80 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EKEPFMFD_00478 6.2e-76 argR K Regulates arginine biosynthesis genes
EKEPFMFD_00479 5.5e-303 recN L May be involved in recombinational repair of damaged DNA
EKEPFMFD_00480 3.3e-15
EKEPFMFD_00481 6.7e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EKEPFMFD_00482 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EKEPFMFD_00483 2.2e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EKEPFMFD_00484 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKEPFMFD_00485 2.5e-21 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKEPFMFD_00486 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EKEPFMFD_00487 7.6e-56 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EKEPFMFD_00488 1.9e-175 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EKEPFMFD_00489 6.7e-128 stp 3.1.3.16 T phosphatase
EKEPFMFD_00490 0.0 KLT serine threonine protein kinase
EKEPFMFD_00491 1.6e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EKEPFMFD_00492 1e-76 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EKEPFMFD_00493 7.3e-29 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EKEPFMFD_00494 2.3e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
EKEPFMFD_00495 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EKEPFMFD_00496 3.6e-58 asp S Asp23 family, cell envelope-related function
EKEPFMFD_00497 5.4e-295 yloV S DAK2 domain fusion protein YloV
EKEPFMFD_00498 9.4e-290 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EKEPFMFD_00499 4.1e-43 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EKEPFMFD_00500 4.5e-162 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EKEPFMFD_00501 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKEPFMFD_00502 3.4e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EKEPFMFD_00503 0.0 smc D Required for chromosome condensation and partitioning
EKEPFMFD_00504 5.1e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EKEPFMFD_00505 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EKEPFMFD_00506 1.1e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EKEPFMFD_00507 3.2e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EKEPFMFD_00508 4.4e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EKEPFMFD_00509 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EKEPFMFD_00510 8.5e-115 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EKEPFMFD_00511 5.4e-239 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EKEPFMFD_00512 3.2e-50 ylxQ J ribosomal protein
EKEPFMFD_00513 1.4e-47 ylxR K Protein of unknown function (DUF448)
EKEPFMFD_00514 8.3e-224 nusA K Participates in both transcription termination and antitermination
EKEPFMFD_00515 9.5e-83 rimP J Required for maturation of 30S ribosomal subunits
EKEPFMFD_00516 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EKEPFMFD_00517 7.8e-219 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EKEPFMFD_00518 5.8e-79 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EKEPFMFD_00519 9.5e-107 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EKEPFMFD_00520 3.8e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EKEPFMFD_00521 1.3e-205 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EKEPFMFD_00522 3.3e-135 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
EKEPFMFD_00523 2.4e-39 argD 2.6.1.11, 2.6.1.17 E acetylornithine
EKEPFMFD_00524 7.2e-150 argD 2.6.1.11, 2.6.1.17 E acetylornithine
EKEPFMFD_00525 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKEPFMFD_00526 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EKEPFMFD_00527 7.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EKEPFMFD_00528 1.8e-134 cdsA 2.7.7.41 I Belongs to the CDS family
EKEPFMFD_00529 3.6e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKEPFMFD_00530 4.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EKEPFMFD_00531 3.8e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EKEPFMFD_00532 5.5e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EKEPFMFD_00533 3.3e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
EKEPFMFD_00534 4.4e-29 yazA L GIY-YIG catalytic domain protein
EKEPFMFD_00535 6e-08 yazA L GIY-YIG catalytic domain protein
EKEPFMFD_00536 1.1e-133 yabB 2.1.1.223 L Methyltransferase small domain
EKEPFMFD_00537 3e-113 plsC 2.3.1.51 I Acyltransferase
EKEPFMFD_00538 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
EKEPFMFD_00539 5.4e-37 ynzC S UPF0291 protein
EKEPFMFD_00540 1.2e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EKEPFMFD_00541 2.2e-213 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
EKEPFMFD_00542 8.9e-52 lutA C Cysteine-rich domain
EKEPFMFD_00543 6.7e-232 lutB C 4Fe-4S dicluster domain
EKEPFMFD_00545 1.6e-25 yitW S Iron-sulfur cluster assembly protein
EKEPFMFD_00546 1e-90 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
EKEPFMFD_00547 1.3e-64 sdaAB 4.3.1.17 E Serine dehydratase beta chain
EKEPFMFD_00550 6.8e-130 K response regulator
EKEPFMFD_00551 6.7e-98 vicK 2.7.13.3 T Histidine kinase
EKEPFMFD_00552 6.1e-227 vicK 2.7.13.3 T Histidine kinase
EKEPFMFD_00553 1.9e-239 yycH S YycH protein
EKEPFMFD_00554 8e-143 yycI S YycH protein
EKEPFMFD_00555 6e-154 vicX 3.1.26.11 S domain protein
EKEPFMFD_00556 3e-208 htrA 3.4.21.107 O serine protease
EKEPFMFD_00557 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EKEPFMFD_00558 1.3e-70 K Transcriptional regulator
EKEPFMFD_00559 3.2e-175 malR K Transcriptional regulator, LacI family
EKEPFMFD_00560 2.8e-249 malT G Major Facilitator
EKEPFMFD_00561 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
EKEPFMFD_00562 1.5e-94 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
EKEPFMFD_00563 1.7e-88 ysdA CP transmembrane transport
EKEPFMFD_00564 8.3e-72 natA S ABC transporter, ATP-binding protein
EKEPFMFD_00565 4e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EKEPFMFD_00566 5.4e-183 D Alpha beta
EKEPFMFD_00567 2.7e-180 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKEPFMFD_00568 2e-214 patA 2.6.1.1 E Aminotransferase
EKEPFMFD_00569 1e-34
EKEPFMFD_00570 0.0 clpL O associated with various cellular activities
EKEPFMFD_00571 2.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKEPFMFD_00572 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EKEPFMFD_00573 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EKEPFMFD_00574 5.7e-163 yvgN C Aldo keto reductase
EKEPFMFD_00575 7.7e-286 glpQ 3.1.4.46 C phosphodiesterase
EKEPFMFD_00576 1.7e-133 manR K PRD domain
EKEPFMFD_00577 1.5e-18 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EKEPFMFD_00578 2.6e-53 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EKEPFMFD_00579 2.5e-39 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
EKEPFMFD_00580 1.4e-126 G Phosphotransferase System
EKEPFMFD_00581 1.1e-108 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
EKEPFMFD_00582 1.2e-131 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EKEPFMFD_00583 6.1e-44 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EKEPFMFD_00584 2.8e-40 ulaB 2.7.1.194 G Phosphotransferase system galactitol-specific IIB component
EKEPFMFD_00585 3.7e-193 ulaA 2.7.1.194 S PTS system sugar-specific permease component
EKEPFMFD_00586 2e-259 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EKEPFMFD_00587 7.8e-123 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EKEPFMFD_00588 2e-135 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
EKEPFMFD_00589 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EKEPFMFD_00590 2.1e-244 glpT G Major Facilitator Superfamily
EKEPFMFD_00591 9.7e-130 qmcA O prohibitin homologues
EKEPFMFD_00593 3.1e-75 uspA T universal stress protein
EKEPFMFD_00594 1.8e-58
EKEPFMFD_00595 2.5e-19
EKEPFMFD_00596 1e-156
EKEPFMFD_00597 8.4e-75 K Transcriptional regulator
EKEPFMFD_00598 1.1e-183 D Alpha beta
EKEPFMFD_00599 3.9e-72 O OsmC-like protein
EKEPFMFD_00600 1.5e-191 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
EKEPFMFD_00601 0.0 yjcE P Sodium proton antiporter
EKEPFMFD_00602 2.1e-08 yvlA
EKEPFMFD_00603 2.4e-113 P Cobalt transport protein
EKEPFMFD_00604 2.8e-252 cbiO1 S ABC transporter, ATP-binding protein
EKEPFMFD_00605 2.3e-99 S ABC-type cobalt transport system, permease component
EKEPFMFD_00606 7.5e-180 iunH2 3.2.2.1 F nucleoside hydrolase
EKEPFMFD_00607 1.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
EKEPFMFD_00608 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
EKEPFMFD_00609 2.8e-32 copZ P Heavy-metal-associated domain
EKEPFMFD_00610 2.6e-100 dps P Belongs to the Dps family
EKEPFMFD_00611 1.6e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
EKEPFMFD_00612 3.2e-56
EKEPFMFD_00613 2.3e-14
EKEPFMFD_00614 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EKEPFMFD_00615 3.6e-125 pgm3 G phosphoglycerate mutase family
EKEPFMFD_00616 1.3e-146 qorB 1.6.5.2 GM NmrA-like family
EKEPFMFD_00617 5.6e-96 L PFAM Integrase catalytic region
EKEPFMFD_00619 9.3e-229 pbuX F xanthine permease
EKEPFMFD_00620 1.8e-170 corA P CorA-like Mg2+ transporter protein
EKEPFMFD_00621 2.2e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EKEPFMFD_00622 2.3e-142 terC P membrane
EKEPFMFD_00623 1e-56 trxA1 O Belongs to the thioredoxin family
EKEPFMFD_00624 6.5e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKEPFMFD_00625 4.8e-157 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
EKEPFMFD_00626 3.3e-183 fruR3 K Transcriptional regulator, LacI family
EKEPFMFD_00627 5.3e-256 pgi 5.3.1.9 G Belongs to the GPI family
EKEPFMFD_00628 2.5e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
EKEPFMFD_00629 4.4e-164 mepA V MATE efflux family protein
EKEPFMFD_00630 8.5e-56 mepA V MATE efflux family protein
EKEPFMFD_00631 2.6e-54 amtB P ammonium transporter
EKEPFMFD_00632 1.8e-150 amtB P ammonium transporter
EKEPFMFD_00633 9.3e-133 XK27_08845 S ABC transporter, ATP-binding protein
EKEPFMFD_00634 3.3e-137 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
EKEPFMFD_00635 5e-179 ABC-SBP S ABC transporter
EKEPFMFD_00636 1.9e-289 S ABC transporter, ATP-binding protein
EKEPFMFD_00637 2.9e-204 nrnB S DHHA1 domain
EKEPFMFD_00638 1.3e-108 M ErfK YbiS YcfS YnhG
EKEPFMFD_00639 1.3e-75 nrdI F NrdI Flavodoxin like
EKEPFMFD_00640 3.7e-106 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
EKEPFMFD_00641 6.7e-181 1.17.4.1 F Ribonucleotide reductase, small chain
EKEPFMFD_00642 5e-267 S Uncharacterized protein conserved in bacteria (DUF2325)
EKEPFMFD_00643 3.3e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
EKEPFMFD_00644 9.9e-177 3.4.11.5 E Releases the N-terminal proline from various substrates
EKEPFMFD_00645 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EKEPFMFD_00646 2.3e-206 yfnA E Amino Acid
EKEPFMFD_00647 3.8e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
EKEPFMFD_00648 9.1e-104 gmk2 2.7.4.8 F Guanylate kinase
EKEPFMFD_00649 4e-83 zur P Belongs to the Fur family
EKEPFMFD_00651 9.1e-167
EKEPFMFD_00652 1.7e-185 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EKEPFMFD_00653 7.3e-92 K Transcriptional regulator (TetR family)
EKEPFMFD_00654 5.5e-16 V domain protein
EKEPFMFD_00655 1.8e-172 V domain protein
EKEPFMFD_00656 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
EKEPFMFD_00657 2.6e-76 EGP Major facilitator Superfamily
EKEPFMFD_00658 3.6e-45 EGP Major facilitator Superfamily
EKEPFMFD_00659 0.0 copA 3.6.3.54 P P-type ATPase
EKEPFMFD_00660 9.5e-52 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EKEPFMFD_00661 1.4e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EKEPFMFD_00662 2.4e-173
EKEPFMFD_00663 1.3e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
EKEPFMFD_00664 6.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EKEPFMFD_00665 2.1e-238 purD 6.3.4.13 F Belongs to the GARS family
EKEPFMFD_00666 8e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EKEPFMFD_00667 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EKEPFMFD_00668 7.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EKEPFMFD_00669 1.8e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EKEPFMFD_00670 2.5e-214 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKEPFMFD_00671 8.5e-191 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKEPFMFD_00672 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKEPFMFD_00673 8.9e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKEPFMFD_00674 2e-100 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EKEPFMFD_00675 1.2e-17 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EKEPFMFD_00676 1.7e-18 K HxlR-like helix-turn-helix
EKEPFMFD_00677 4.3e-66 IQ Dehydrogenase
EKEPFMFD_00678 2e-96 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
EKEPFMFD_00679 2e-230 S response to antibiotic
EKEPFMFD_00680 7.5e-99 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
EKEPFMFD_00681 1.2e-254 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EKEPFMFD_00682 2.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EKEPFMFD_00683 3.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EKEPFMFD_00684 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EKEPFMFD_00685 1.9e-57 K AI-2E family transporter
EKEPFMFD_00686 4.1e-75 K AI-2E family transporter
EKEPFMFD_00687 1.4e-15 K transcriptional regulator
EKEPFMFD_00688 6.3e-229 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
EKEPFMFD_00689 4.5e-91 pstS P Phosphate ABC transporter substrate-binding protein, PhoT family
EKEPFMFD_00690 2.4e-98 pstC P probably responsible for the translocation of the substrate across the membrane
EKEPFMFD_00691 1.3e-103 pstA P Phosphate transport system permease protein PstA
EKEPFMFD_00692 1.6e-95 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EKEPFMFD_00693 1.1e-203 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EKEPFMFD_00694 3.6e-210 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
EKEPFMFD_00695 5.3e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EKEPFMFD_00696 3.9e-165 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EKEPFMFD_00697 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EKEPFMFD_00698 6.2e-88 ypmB S Protein conserved in bacteria
EKEPFMFD_00699 6e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
EKEPFMFD_00700 1.7e-131 dnaD L DnaD domain protein
EKEPFMFD_00701 3.7e-121 ypuA S Protein of unknown function (DUF1002)
EKEPFMFD_00702 1.7e-176 C Aldo keto reductase family protein
EKEPFMFD_00703 1.8e-159 EG EamA-like transporter family
EKEPFMFD_00704 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
EKEPFMFD_00705 1.9e-115 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EKEPFMFD_00706 1.1e-107 ypsA S Belongs to the UPF0398 family
EKEPFMFD_00707 2.3e-57 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EKEPFMFD_00708 0.0 tetP J elongation factor G
EKEPFMFD_00709 2.6e-48 tetP J elongation factor G
EKEPFMFD_00710 3.4e-211 S Type IV secretion-system coupling protein DNA-binding domain
EKEPFMFD_00711 8.9e-83 F Hydrolase, NUDIX family
EKEPFMFD_00712 1.9e-91 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EKEPFMFD_00713 3.9e-96 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EKEPFMFD_00714 2.4e-192 ytjP 3.5.1.18 E Dipeptidase
EKEPFMFD_00715 2.4e-204 arcD S C4-dicarboxylate anaerobic carrier
EKEPFMFD_00716 8e-258 nylA 3.5.1.4 J Belongs to the amidase family
EKEPFMFD_00717 3.3e-40 L Phage terminase, small subunit
EKEPFMFD_00718 1.8e-267 S Phage Terminase
EKEPFMFD_00720 2.3e-144 S portal protein
EKEPFMFD_00721 1.2e-79 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
EKEPFMFD_00722 2.5e-121 S Phage capsid family
EKEPFMFD_00723 1.3e-29 S Phage gp6-like head-tail connector protein
EKEPFMFD_00724 5.1e-33 S Phage head-tail joining protein
EKEPFMFD_00725 2.4e-23
EKEPFMFD_00726 9.4e-49 S Phage tail tube protein
EKEPFMFD_00727 4.8e-27
EKEPFMFD_00728 3.4e-187 M Phage tail tape measure protein TP901
EKEPFMFD_00729 1e-79 S Phage tail protein
EKEPFMFD_00730 6.1e-138 rny D peptidase
EKEPFMFD_00731 4.7e-87 spoIVFA GT2,GT4 D peptidase
EKEPFMFD_00734 3.4e-32 S GDSL-like Lipase/Acylhydrolase
EKEPFMFD_00735 3.2e-57
EKEPFMFD_00737 6.5e-11
EKEPFMFD_00738 3.9e-29 S Bacteriophage holin of superfamily 6 (Holin_LLH)
EKEPFMFD_00739 6.3e-154 ps461 3.5.1.104 M hydrolase, family 25
EKEPFMFD_00740 1.7e-38
EKEPFMFD_00742 4.4e-09 tnp L MULE transposase domain
EKEPFMFD_00743 3.6e-45
EKEPFMFD_00744 6.2e-165 I alpha/beta hydrolase fold
EKEPFMFD_00745 5.7e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EKEPFMFD_00746 1.9e-167 mleP2 S Sodium Bile acid symporter family
EKEPFMFD_00747 1.5e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
EKEPFMFD_00748 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
EKEPFMFD_00750 1.6e-84 ydcK S Belongs to the SprT family
EKEPFMFD_00751 0.0 yhgF K Tex-like protein N-terminal domain protein
EKEPFMFD_00752 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EKEPFMFD_00753 9.4e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EKEPFMFD_00754 1.6e-126 gntR1 K UbiC transcription regulator-associated domain protein
EKEPFMFD_00755 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EKEPFMFD_00756 2e-112
EKEPFMFD_00759 2.1e-162 yjjH S Calcineurin-like phosphoesterase
EKEPFMFD_00760 4.5e-256 dtpT U amino acid peptide transporter
EKEPFMFD_00761 1.9e-133 D nuclear chromosome segregation
EKEPFMFD_00762 3.9e-29 L Transposase
EKEPFMFD_00766 9.2e-23 L Plasmid pRiA4b ORF-3-like protein
EKEPFMFD_00767 1.6e-111 IQ KR domain
EKEPFMFD_00768 7.2e-198 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
EKEPFMFD_00769 3.6e-165 luxE 6.2.1.19 H Acyl-protein synthetase, LuxE
EKEPFMFD_00770 1.1e-202 F Permease
EKEPFMFD_00771 2.2e-236 cycA E Amino acid permease
EKEPFMFD_00773 2.4e-28 M Glycosyltransferase like family 2
EKEPFMFD_00774 7.2e-116 yecS E ABC transporter permease
EKEPFMFD_00775 5.7e-155 yckB ET Belongs to the bacterial solute-binding protein 3 family
EKEPFMFD_00776 3.4e-106 XK27_02070 S Nitroreductase family
EKEPFMFD_00777 1.2e-70 rnhA 3.1.26.4 L Ribonuclease HI
EKEPFMFD_00778 1.7e-70 esbA S Family of unknown function (DUF5322)
EKEPFMFD_00779 5.6e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EKEPFMFD_00780 6.5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EKEPFMFD_00781 3.6e-207 carA 6.3.5.5 F Belongs to the CarA family
EKEPFMFD_00782 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EKEPFMFD_00783 3.8e-108 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
EKEPFMFD_00784 4.6e-163 K Bacterial regulatory helix-turn-helix protein, lysR family
EKEPFMFD_00785 2e-64 S Enoyl-(Acyl carrier protein) reductase
EKEPFMFD_00786 3.7e-74 akr5f 1.1.1.346 S aldo keto reductase
EKEPFMFD_00787 5.3e-36 S Bacterial transferase hexapeptide (six repeats)
EKEPFMFD_00788 8.6e-37 C Flavodoxin
EKEPFMFD_00789 1.3e-94 P nitric oxide dioxygenase activity
EKEPFMFD_00790 4.6e-120 FbpA K Fibronectin-binding protein
EKEPFMFD_00791 1e-162 FbpA K Fibronectin-binding protein
EKEPFMFD_00792 3.2e-161 degV S EDD domain protein, DegV family
EKEPFMFD_00793 1.2e-95
EKEPFMFD_00794 3.3e-72 S Belongs to the UPF0246 family
EKEPFMFD_00795 2.5e-40 S Belongs to the UPF0246 family
EKEPFMFD_00796 1.2e-115 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
EKEPFMFD_00797 4.5e-112 ylbE GM NAD(P)H-binding
EKEPFMFD_00798 3.3e-97 K Acetyltransferase (GNAT) domain
EKEPFMFD_00799 1.3e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EKEPFMFD_00800 3.6e-230 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EKEPFMFD_00801 2.2e-282 thrC 4.2.3.1 E Threonine synthase
EKEPFMFD_00802 1.1e-30 azlC E azaleucine resistance protein AzlC
EKEPFMFD_00803 1.2e-62 azlC E azaleucine resistance protein AzlC
EKEPFMFD_00804 5.3e-53 azlD E Branched-chain amino acid transport
EKEPFMFD_00805 1.6e-54 yphJ 4.1.1.44 S decarboxylase
EKEPFMFD_00806 7.5e-74 lytE M Lysin motif
EKEPFMFD_00807 4.9e-148 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
EKEPFMFD_00808 9.3e-211 oatA I Acyltransferase
EKEPFMFD_00809 7.3e-52
EKEPFMFD_00810 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EKEPFMFD_00811 2.1e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKEPFMFD_00812 7.7e-115 ybbR S YbbR-like protein
EKEPFMFD_00813 9.6e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EKEPFMFD_00814 5.7e-166 murB 1.3.1.98 M Cell wall formation
EKEPFMFD_00815 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
EKEPFMFD_00816 3.3e-89 K Acetyltransferase (GNAT) domain
EKEPFMFD_00817 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
EKEPFMFD_00818 5.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EKEPFMFD_00819 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EKEPFMFD_00820 1.4e-109 yxjI
EKEPFMFD_00821 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EKEPFMFD_00822 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EKEPFMFD_00823 4.5e-33 secG U Preprotein translocase
EKEPFMFD_00824 6.4e-290 clcA P chloride
EKEPFMFD_00825 1.6e-252 yifK E Amino acid permease
EKEPFMFD_00826 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EKEPFMFD_00827 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EKEPFMFD_00828 2.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EKEPFMFD_00829 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EKEPFMFD_00830 1.5e-14
EKEPFMFD_00831 4.4e-200 L Belongs to the 'phage' integrase family
EKEPFMFD_00832 2.9e-176 yobV1 K WYL domain
EKEPFMFD_00833 1.3e-241 XK27_08635 S UPF0210 protein
EKEPFMFD_00834 2.5e-40 gcvR T Belongs to the UPF0237 family
EKEPFMFD_00835 1.7e-99 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EKEPFMFD_00836 3.4e-52 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EKEPFMFD_00837 1.7e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EKEPFMFD_00838 6.9e-203 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
EKEPFMFD_00839 2.1e-216 G Transporter, major facilitator family protein
EKEPFMFD_00840 5.9e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EKEPFMFD_00841 6.9e-158 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EKEPFMFD_00842 5.7e-54 ydiI Q Thioesterase superfamily
EKEPFMFD_00844 6.5e-183 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
EKEPFMFD_00845 1.7e-107 citR K sugar-binding domain protein
EKEPFMFD_00846 6.8e-151 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
EKEPFMFD_00847 2.2e-110 S Membrane transport protein
EKEPFMFD_00848 3.3e-88 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EKEPFMFD_00849 7e-36 citD C Covalent carrier of the coenzyme of citrate lyase
EKEPFMFD_00850 2.5e-100 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
EKEPFMFD_00851 1.5e-27 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
EKEPFMFD_00852 2.5e-238 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
EKEPFMFD_00853 4.4e-136 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
EKEPFMFD_00854 1.8e-70 ydjP I Alpha/beta hydrolase family
EKEPFMFD_00855 5.7e-106 L Integrase
EKEPFMFD_00856 1.6e-44 K transcriptional regulator
EKEPFMFD_00857 4.6e-88 GM NmrA-like family
EKEPFMFD_00858 4.9e-36 C Flavodoxin
EKEPFMFD_00859 6.1e-122 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
EKEPFMFD_00860 5.2e-79
EKEPFMFD_00861 1.3e-186 ydaM M Glycosyl transferase family group 2
EKEPFMFD_00862 1.1e-121 G Glycosyl hydrolases family 8
EKEPFMFD_00863 7.2e-142 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
EKEPFMFD_00864 8.7e-107 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKEPFMFD_00865 2.4e-170 ybeC E amino acid
EKEPFMFD_00866 1.8e-93 ybeC E amino acid
EKEPFMFD_00867 4e-133 pnuC H nicotinamide mononucleotide transporter
EKEPFMFD_00868 8.6e-204 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EKEPFMFD_00869 4.4e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EKEPFMFD_00870 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
EKEPFMFD_00871 3.6e-117 dedA S SNARE associated Golgi protein
EKEPFMFD_00872 0.0 helD 3.6.4.12 L DNA helicase
EKEPFMFD_00873 7.3e-161 EG EamA-like transporter family
EKEPFMFD_00874 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EKEPFMFD_00875 8.3e-134 IQ Dehydrogenase reductase
EKEPFMFD_00876 1.8e-101 2.3.1.128 K acetyltransferase
EKEPFMFD_00877 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
EKEPFMFD_00878 8.4e-131 sptS 2.7.13.3 T Histidine kinase
EKEPFMFD_00879 1.4e-79 K response regulator
EKEPFMFD_00880 4.3e-112 2.7.6.5 T Region found in RelA / SpoT proteins
EKEPFMFD_00881 1.1e-268 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EKEPFMFD_00882 1.3e-209 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EKEPFMFD_00883 4.3e-53 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EKEPFMFD_00884 1.7e-153 yitU 3.1.3.104 S hydrolase
EKEPFMFD_00885 7.7e-166 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EKEPFMFD_00886 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EKEPFMFD_00887 9.6e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EKEPFMFD_00888 1.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EKEPFMFD_00889 4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EKEPFMFD_00890 2.3e-72 ycsI S Protein of unknown function (DUF1445)
EKEPFMFD_00893 8.7e-08 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EKEPFMFD_00894 2.4e-17 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EKEPFMFD_00899 2.2e-67 ubiD 4.1.1.98 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EKEPFMFD_00900 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EKEPFMFD_00901 3.7e-260 yfnA E Amino Acid
EKEPFMFD_00902 1.4e-141 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EKEPFMFD_00903 1.8e-87 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EKEPFMFD_00904 5.4e-40 ylqC S Belongs to the UPF0109 family
EKEPFMFD_00905 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EKEPFMFD_00906 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
EKEPFMFD_00907 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EKEPFMFD_00908 6.1e-152 pstA P Phosphate transport system permease protein PstA
EKEPFMFD_00909 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
EKEPFMFD_00910 5.1e-159 pstS P Phosphate
EKEPFMFD_00911 3.7e-128 K Transcriptional regulatory protein, C-terminal domain protein
EKEPFMFD_00912 1.6e-68
EKEPFMFD_00914 1.6e-42 tnp L MULE transposase domain
EKEPFMFD_00915 1.4e-245 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
EKEPFMFD_00916 3.7e-51 trxA O Belongs to the thioredoxin family
EKEPFMFD_00917 1.9e-151 mleP3 S Membrane transport protein
EKEPFMFD_00919 8.2e-241 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EKEPFMFD_00920 6.3e-239 yfnA E amino acid
EKEPFMFD_00921 4.6e-61 S NADPH-dependent FMN reductase
EKEPFMFD_00923 3.6e-154 L Thioesterase-like superfamily
EKEPFMFD_00924 3.6e-51 lacA S transferase hexapeptide repeat
EKEPFMFD_00925 6.2e-260 argH 4.3.2.1 E argininosuccinate lyase
EKEPFMFD_00926 1.6e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EKEPFMFD_00927 5.6e-259 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKEPFMFD_00928 7.1e-60 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKEPFMFD_00929 2.8e-97 K Transcriptional regulator
EKEPFMFD_00930 2e-78 L Transposase
EKEPFMFD_00932 4.4e-48 S FMN_bind
EKEPFMFD_00933 1.3e-272 yhcA V ABC transporter, ATP-binding protein
EKEPFMFD_00934 8.2e-61 yhcA V ABC transporter, ATP-binding protein
EKEPFMFD_00935 2e-115 bm3R1 K Bacterial regulatory proteins, tetR family
EKEPFMFD_00936 5.4e-50 ybjQ S Belongs to the UPF0145 family
EKEPFMFD_00938 3e-19 S Plasmid maintenance system killer
EKEPFMFD_00939 1.2e-27 rocF 3.5.3.1, 3.5.3.11 E Arginase family
EKEPFMFD_00940 1.3e-21 rocF 3.5.3.1, 3.5.3.11 E Arginase family
EKEPFMFD_00941 7.2e-17 rocF 3.5.3.1, 3.5.3.11 E Arginase family
EKEPFMFD_00942 2.2e-58 1.3.1.9 S Nitronate monooxygenase
EKEPFMFD_00943 4.3e-95 1.3.1.9 S Nitronate monooxygenase
EKEPFMFD_00944 1.5e-52 K Helix-turn-helix domain
EKEPFMFD_00945 8e-105 S Domain of unknown function (DUF4767)
EKEPFMFD_00946 1.1e-79
EKEPFMFD_00947 9.3e-09 S Domain of unknown function (DUF4767)
EKEPFMFD_00948 4.6e-149 S Phage integrase family
EKEPFMFD_00949 1.5e-92 dut S Protein conserved in bacteria
EKEPFMFD_00950 1.6e-174
EKEPFMFD_00951 9.2e-148
EKEPFMFD_00952 4.7e-13
EKEPFMFD_00953 2.4e-127 glnA 6.3.1.2 E glutamine synthetase
EKEPFMFD_00954 1.6e-95 glnA 6.3.1.2 E glutamine synthetase
EKEPFMFD_00955 5.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EKEPFMFD_00956 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
EKEPFMFD_00957 1.5e-71 yqhL P Rhodanese-like protein
EKEPFMFD_00958 1.7e-179 glk 2.7.1.2 G Glucokinase
EKEPFMFD_00959 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
EKEPFMFD_00960 1.8e-116 gluP 3.4.21.105 S Peptidase, S54 family
EKEPFMFD_00961 9.2e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EKEPFMFD_00962 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EKEPFMFD_00963 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
EKEPFMFD_00964 0.0 S membrane
EKEPFMFD_00965 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EKEPFMFD_00966 5.2e-116 udk 2.7.1.48 F Cytidine monophosphokinase
EKEPFMFD_00967 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EKEPFMFD_00968 5.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EKEPFMFD_00969 7.8e-60 yodB K Transcriptional regulator, HxlR family
EKEPFMFD_00970 2.9e-90 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
EKEPFMFD_00971 2.2e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKEPFMFD_00972 1.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EKEPFMFD_00973 1.4e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EKEPFMFD_00974 1.1e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EKEPFMFD_00975 1.3e-230 V MatE
EKEPFMFD_00976 5.8e-280 arlS 2.7.13.3 T Histidine kinase
EKEPFMFD_00977 1.6e-120 K response regulator
EKEPFMFD_00978 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EKEPFMFD_00979 2.7e-97 yceD S Uncharacterized ACR, COG1399
EKEPFMFD_00980 1.2e-213 ylbM S Belongs to the UPF0348 family
EKEPFMFD_00981 1.8e-98 yqeM Q Methyltransferase
EKEPFMFD_00982 6.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EKEPFMFD_00983 4.7e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
EKEPFMFD_00984 6e-93 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EKEPFMFD_00985 2.6e-49 yhbY J RNA-binding protein
EKEPFMFD_00986 4.2e-214 yqeH S Ribosome biogenesis GTPase YqeH
EKEPFMFD_00987 5.4e-95 yqeG S HAD phosphatase, family IIIA
EKEPFMFD_00988 2.6e-36 yoaK S Protein of unknown function (DUF1275)
EKEPFMFD_00989 1e-08 yoaK S Protein of unknown function (DUF1275)
EKEPFMFD_00990 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EKEPFMFD_00991 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EKEPFMFD_00992 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EKEPFMFD_00993 6.2e-171 dnaI L Primosomal protein DnaI
EKEPFMFD_00994 2.2e-246 dnaB L replication initiation and membrane attachment
EKEPFMFD_00995 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EKEPFMFD_00996 2.1e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EKEPFMFD_00997 4.7e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EKEPFMFD_00998 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKEPFMFD_00999 2.5e-138 aroD S Serine hydrolase (FSH1)
EKEPFMFD_01000 6.9e-114 ybhL S Belongs to the BI1 family
EKEPFMFD_01001 1e-248 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EKEPFMFD_01002 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EKEPFMFD_01003 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EKEPFMFD_01004 3.3e-58 ytzB S Small secreted protein
EKEPFMFD_01005 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EKEPFMFD_01006 5.7e-195 ecsB U ABC transporter
EKEPFMFD_01007 6.4e-34 ecsA V ABC transporter, ATP-binding protein
EKEPFMFD_01008 2.1e-88 ecsA V ABC transporter, ATP-binding protein
EKEPFMFD_01009 1.5e-76 hit FG histidine triad
EKEPFMFD_01011 1.3e-147 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EKEPFMFD_01012 2.8e-179 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
EKEPFMFD_01013 9.8e-56 yheA S Belongs to the UPF0342 family
EKEPFMFD_01014 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EKEPFMFD_01015 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EKEPFMFD_01017 7.2e-35
EKEPFMFD_01019 1e-199 folP 2.5.1.15 H dihydropteroate synthase
EKEPFMFD_01020 5.9e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
EKEPFMFD_01021 1.4e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EKEPFMFD_01022 3.4e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
EKEPFMFD_01023 9.2e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
EKEPFMFD_01024 8.4e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EKEPFMFD_01025 7.6e-118 S CAAX protease self-immunity
EKEPFMFD_01026 2.9e-182 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
EKEPFMFD_01027 3.6e-111
EKEPFMFD_01028 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
EKEPFMFD_01029 2e-160 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EKEPFMFD_01030 2e-250 S Putative peptidoglycan binding domain
EKEPFMFD_01031 2.1e-85 uspA T Belongs to the universal stress protein A family
EKEPFMFD_01032 2.3e-270 pepV 3.5.1.18 E dipeptidase PepV
EKEPFMFD_01033 1.2e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EKEPFMFD_01034 4.7e-154 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EKEPFMFD_01035 5.8e-61 3.2.1.23 S Domain of unknown function DUF302
EKEPFMFD_01036 5.8e-297 ytgP S Polysaccharide biosynthesis protein
EKEPFMFD_01037 2.6e-42
EKEPFMFD_01038 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EKEPFMFD_01039 3.5e-60
EKEPFMFD_01040 2.3e-207 lmrP E Major Facilitator Superfamily
EKEPFMFD_01041 2.7e-164 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EKEPFMFD_01042 1.2e-68 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EKEPFMFD_01043 2e-74 rplI J Binds to the 23S rRNA
EKEPFMFD_01044 1.3e-67 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EKEPFMFD_01045 1.3e-293 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EKEPFMFD_01046 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EKEPFMFD_01047 7.4e-87 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EKEPFMFD_01048 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
EKEPFMFD_01049 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKEPFMFD_01050 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKEPFMFD_01051 5.3e-201 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EKEPFMFD_01052 2.2e-34 yaaA S S4 domain protein YaaA
EKEPFMFD_01053 3e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EKEPFMFD_01054 1.5e-247 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EKEPFMFD_01056 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
EKEPFMFD_01057 1.9e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EKEPFMFD_01058 9.8e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EKEPFMFD_01059 2.1e-15 jag S R3H domain protein
EKEPFMFD_01060 1e-105 jag S R3H domain protein
EKEPFMFD_01061 1.3e-73 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EKEPFMFD_01062 3.8e-168 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EKEPFMFD_01063 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EKEPFMFD_01064 4.5e-31 L HNH nucleases
EKEPFMFD_01065 9.9e-33 doc S Fic/DOC family
EKEPFMFD_01066 1.5e-52 gepA K Protein of unknown function (DUF4065)
EKEPFMFD_01067 1e-20
EKEPFMFD_01073 2.9e-41 rusA L Endodeoxyribonuclease RusA
EKEPFMFD_01076 4.6e-42 dnaC 3.4.21.53 L IstB-like ATP binding protein
EKEPFMFD_01077 5.4e-106 S calcium ion binding
EKEPFMFD_01078 5.4e-71 S Putative HNHc nuclease
EKEPFMFD_01079 3.4e-34 S Single-strand binding protein family
EKEPFMFD_01080 3.9e-26 S Erf family
EKEPFMFD_01085 3.3e-10
EKEPFMFD_01086 7.2e-10 S Domain of unknown function (DUF771)
EKEPFMFD_01091 8.2e-113 S DNA binding
EKEPFMFD_01092 2e-09 S Domain of unknown function (DUF771)
EKEPFMFD_01093 2e-20
EKEPFMFD_01096 1.2e-17 ps115 K Helix-turn-helix XRE-family like proteins
EKEPFMFD_01097 6.4e-26 xkdA E Zn peptidase
EKEPFMFD_01099 3.3e-15 L nuclease
EKEPFMFD_01101 6e-116
EKEPFMFD_01103 9.8e-54
EKEPFMFD_01104 8.6e-81
EKEPFMFD_01106 1.8e-41 S Phage integrase family
EKEPFMFD_01107 1.3e-93 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKEPFMFD_01108 1e-156 P Belongs to the nlpA lipoprotein family
EKEPFMFD_01109 4.8e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKEPFMFD_01110 2.1e-115 S Protein of unknown function (DUF554)
EKEPFMFD_01111 3.1e-24 P Cadmium resistance transporter
EKEPFMFD_01112 4.7e-55 P Cadmium resistance transporter
EKEPFMFD_01113 4.8e-178 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
EKEPFMFD_01114 5.8e-58 iscS 2.8.1.7 E Aminotransferase class V
EKEPFMFD_01115 3.2e-147 iscS 2.8.1.7 E Aminotransferase class V
EKEPFMFD_01116 1e-52 C FMN binding
EKEPFMFD_01117 2.5e-200 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EKEPFMFD_01118 8.3e-108 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
EKEPFMFD_01119 1.7e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
EKEPFMFD_01120 5.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EKEPFMFD_01121 4.2e-217 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKEPFMFD_01122 1.3e-81 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EKEPFMFD_01123 2.8e-98 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EKEPFMFD_01124 4.3e-109 C aldo keto reductase
EKEPFMFD_01125 2.4e-110 3.1.3.73 G phosphoglycerate mutase
EKEPFMFD_01126 1.9e-09
EKEPFMFD_01127 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EKEPFMFD_01128 1.8e-193 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EKEPFMFD_01129 5.7e-51 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Histidine biosynthesis bifunctional protein hisIE
EKEPFMFD_01130 8.9e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EKEPFMFD_01131 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EKEPFMFD_01132 4.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EKEPFMFD_01133 2.6e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EKEPFMFD_01134 5e-211 EG GntP family permease
EKEPFMFD_01135 3.3e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EKEPFMFD_01136 2e-211 iscS2 2.8.1.7 E Aminotransferase class V
EKEPFMFD_01137 4.9e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EKEPFMFD_01138 1.8e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EKEPFMFD_01139 1.6e-08
EKEPFMFD_01140 2.8e-146 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKEPFMFD_01141 5.3e-133 S Membrane
EKEPFMFD_01142 3.7e-75 4.4.1.5 E Glyoxalase
EKEPFMFD_01143 7.2e-83 yueI S Protein of unknown function (DUF1694)
EKEPFMFD_01144 4.9e-235 rarA L recombination factor protein RarA
EKEPFMFD_01146 6.8e-81 usp6 T universal stress protein
EKEPFMFD_01147 2.4e-150 2.3.1.19 K Helix-turn-helix XRE-family like proteins
EKEPFMFD_01148 7.8e-61
EKEPFMFD_01149 4.9e-112 yicL EG EamA-like transporter family
EKEPFMFD_01150 3.2e-72 S Domain of unknown function (DUF4352)
EKEPFMFD_01151 0.0 1.3.5.4 C FAD binding domain
EKEPFMFD_01152 4.1e-167 K LysR substrate binding domain
EKEPFMFD_01153 1.6e-157 rssA S Phospholipase, patatin family
EKEPFMFD_01154 7.4e-214 phbA 2.3.1.9 I Belongs to the thiolase family
EKEPFMFD_01155 2e-176 S AI-2E family transporter
EKEPFMFD_01156 9.1e-125 S membrane transporter protein
EKEPFMFD_01157 3.5e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
EKEPFMFD_01158 1.2e-191 V Beta-lactamase
EKEPFMFD_01159 7.3e-225
EKEPFMFD_01161 2.9e-151 S Alpha/beta hydrolase of unknown function (DUF915)
EKEPFMFD_01162 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKEPFMFD_01163 2e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
EKEPFMFD_01164 2.9e-162 endA F DNA RNA non-specific endonuclease
EKEPFMFD_01165 3.7e-265 pipD E Dipeptidase
EKEPFMFD_01167 6.7e-140 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EKEPFMFD_01168 4.9e-44 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EKEPFMFD_01169 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EKEPFMFD_01170 7.1e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EKEPFMFD_01171 9.5e-242 steT E amino acid
EKEPFMFD_01172 1.7e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EKEPFMFD_01173 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EKEPFMFD_01174 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
EKEPFMFD_01175 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EKEPFMFD_01176 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EKEPFMFD_01177 2.5e-98 sigH K Belongs to the sigma-70 factor family
EKEPFMFD_01178 1.3e-134 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKEPFMFD_01179 1.2e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EKEPFMFD_01180 3.6e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EKEPFMFD_01181 2.8e-64 ywlG S Belongs to the UPF0340 family
EKEPFMFD_01182 2.8e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKEPFMFD_01183 2e-203 yacL S domain protein
EKEPFMFD_01184 8e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EKEPFMFD_01185 1.9e-95 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
EKEPFMFD_01186 3.5e-54 HA62_12640 S GCN5-related N-acetyl-transferase
EKEPFMFD_01187 8.7e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EKEPFMFD_01188 1.2e-93 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
EKEPFMFD_01189 9.8e-263 pepC 3.4.22.40 E Peptidase C1-like family
EKEPFMFD_01190 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
EKEPFMFD_01191 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EKEPFMFD_01192 4.5e-255 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EKEPFMFD_01193 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKEPFMFD_01194 3.1e-159 S Tetratricopeptide repeat
EKEPFMFD_01195 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EKEPFMFD_01196 3.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EKEPFMFD_01197 5.4e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EKEPFMFD_01198 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
EKEPFMFD_01199 9.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
EKEPFMFD_01201 1.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EKEPFMFD_01202 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EKEPFMFD_01203 3.3e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EKEPFMFD_01204 1.6e-174 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EKEPFMFD_01205 7.3e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EKEPFMFD_01206 1.5e-297 recJ L Single-stranded-DNA-specific exonuclease RecJ
EKEPFMFD_01207 5.3e-113 recJ L Single-stranded-DNA-specific exonuclease RecJ
EKEPFMFD_01208 7e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKEPFMFD_01209 4.7e-252 yifK E Amino acid permease
EKEPFMFD_01211 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EKEPFMFD_01212 1.4e-231 N Uncharacterized conserved protein (DUF2075)
EKEPFMFD_01213 4.1e-55 S SNARE associated Golgi protein
EKEPFMFD_01214 8.4e-78 ndk 2.7.4.6 F Belongs to the NDK family
EKEPFMFD_01215 1e-96 padR K Virulence activator alpha C-term
EKEPFMFD_01216 1.6e-95 padC Q Phenolic acid decarboxylase
EKEPFMFD_01218 6.2e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
EKEPFMFD_01220 1.4e-142 ET Bacterial periplasmic substrate-binding proteins
EKEPFMFD_01221 2.3e-158 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EKEPFMFD_01222 1e-164 aadAT EK Aminotransferase, class I
EKEPFMFD_01223 4.9e-17
EKEPFMFD_01224 9.3e-171 S Beta-lactamase superfamily domain
EKEPFMFD_01225 4.2e-30 2.7.1.194 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EKEPFMFD_01226 7.6e-183 S PTS system sugar-specific permease component
EKEPFMFD_01227 8.2e-39 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EKEPFMFD_01228 6.6e-71 gntR K rpiR family
EKEPFMFD_01229 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
EKEPFMFD_01230 2.5e-170 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKEPFMFD_01231 2.1e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
EKEPFMFD_01232 1.9e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EKEPFMFD_01233 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKEPFMFD_01234 8e-39 ptsH G phosphocarrier protein HPR
EKEPFMFD_01236 0.0 clpE O Belongs to the ClpA ClpB family
EKEPFMFD_01237 2.4e-57 clpE O Belongs to the ClpA ClpB family
EKEPFMFD_01238 8.7e-125 3.6.1.13, 3.6.1.55 F NUDIX domain
EKEPFMFD_01239 9.2e-109 pncA Q Isochorismatase family
EKEPFMFD_01240 2e-239 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EKEPFMFD_01241 3.8e-97 S Pfam:DUF3816
EKEPFMFD_01242 2.8e-64 L Resolvase, N-terminal domain
EKEPFMFD_01243 9.6e-95 L Probable transposase
EKEPFMFD_01244 3.9e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
EKEPFMFD_01245 2.1e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKEPFMFD_01246 1.1e-161 EG EamA-like transporter family
EKEPFMFD_01247 7.3e-244 yxbA 6.3.1.12 S ATP-grasp enzyme
EKEPFMFD_01249 1.2e-137 xth 3.1.11.2 L exodeoxyribonuclease III
EKEPFMFD_01250 3.7e-29
EKEPFMFD_01252 4.9e-07 S YSIRK type signal peptide
EKEPFMFD_01253 5e-235 kgtP EGP Sugar (and other) transporter
EKEPFMFD_01254 1.2e-140 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
EKEPFMFD_01255 2.9e-152 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKEPFMFD_01256 2.8e-149 isdE P Periplasmic binding protein
EKEPFMFD_01257 1e-94 M Iron Transport-associated domain
EKEPFMFD_01258 2.6e-90 isdH M Iron Transport-associated domain
EKEPFMFD_01260 1.7e-54 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EKEPFMFD_01261 2.1e-56 ydzE EG EamA-like transporter family
EKEPFMFD_01262 1.5e-90 P Cadmium resistance transporter
EKEPFMFD_01263 7.7e-97 C aldo keto reductase
EKEPFMFD_01264 6.4e-19 S Uncharacterized protein conserved in bacteria (DUF2255)
EKEPFMFD_01266 3.3e-83 C Aldo keto reductase
EKEPFMFD_01267 2.8e-30 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EKEPFMFD_01268 1.9e-35 S Cyclophilin-like
EKEPFMFD_01269 8e-56 C Flavodoxin
EKEPFMFD_01270 7.7e-91 K Bacterial regulatory helix-turn-helix protein, lysR family
EKEPFMFD_01272 5.1e-156 L hmm pf00665
EKEPFMFD_01273 1.8e-183 ycsG P Natural resistance-associated macrophage protein
EKEPFMFD_01274 2.3e-50 ycsF S LamB/YcsF family
EKEPFMFD_01275 1.1e-18 ycsF S LamB/YcsF family
EKEPFMFD_01276 4.5e-130 ycsI S Protein of unknown function (DUF1445)
EKEPFMFD_01277 4.7e-11 ycsF S LamB/YcsF family
EKEPFMFD_01278 7.1e-256 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
EKEPFMFD_01279 5.9e-52 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EKEPFMFD_01280 2.7e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
EKEPFMFD_01281 2.3e-133 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
EKEPFMFD_01282 1.9e-71 K helix_turn_helix, mercury resistance
EKEPFMFD_01283 4.2e-80 S Psort location Cytoplasmic, score
EKEPFMFD_01284 2.4e-281 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
EKEPFMFD_01285 1.1e-92 wecD K Acetyltransferase (GNAT) family
EKEPFMFD_01286 2.9e-102 3.2.1.17 NU mannosyl-glycoprotein
EKEPFMFD_01287 5.1e-127 asnA 6.3.1.1 F aspartate--ammonia ligase
EKEPFMFD_01288 2.7e-15 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EKEPFMFD_01289 4.6e-16 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
EKEPFMFD_01290 2.5e-211 2.1.1.14 E methionine synthase, vitamin-B12 independent
EKEPFMFD_01291 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EKEPFMFD_01292 1.9e-28 S Cytochrome B5
EKEPFMFD_01296 2.7e-172 lmrB EGP Major facilitator Superfamily
EKEPFMFD_01297 6.9e-67 lmrB EGP Major facilitator Superfamily
EKEPFMFD_01298 2.1e-94 K transcriptional regulator
EKEPFMFD_01299 3.6e-70 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
EKEPFMFD_01300 0.0 L Helicase C-terminal domain protein
EKEPFMFD_01301 7.3e-225 L Helicase C-terminal domain protein
EKEPFMFD_01302 4.6e-54 S MazG-like family
EKEPFMFD_01303 2.6e-106 lssY 3.6.1.27 I Acid phosphatase homologues
EKEPFMFD_01304 1.2e-196 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
EKEPFMFD_01305 2.2e-96
EKEPFMFD_01306 2.7e-222 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EKEPFMFD_01307 7.7e-150 ponA V Beta-lactamase enzyme family
EKEPFMFD_01308 8.4e-263 yjeM E Amino Acid
EKEPFMFD_01310 1.1e-109
EKEPFMFD_01311 6.8e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
EKEPFMFD_01312 7.1e-164 K LysR substrate binding domain
EKEPFMFD_01313 1.2e-61 GM NAD(P)H-binding
EKEPFMFD_01314 5.2e-259 S Uncharacterized protein conserved in bacteria (DUF2252)
EKEPFMFD_01315 2.7e-293 scrB 3.2.1.26 GH32 G invertase
EKEPFMFD_01316 6.4e-177 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
EKEPFMFD_01317 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
EKEPFMFD_01318 1.5e-106 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EKEPFMFD_01319 1e-08 nlhH_1 I acetylesterase activity
EKEPFMFD_01320 7e-21 nlhH_1 I Carboxylesterase family
EKEPFMFD_01321 8.1e-80 mleR K LysR family
EKEPFMFD_01322 2.3e-165 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
EKEPFMFD_01323 1.6e-46 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
EKEPFMFD_01324 5.4e-184 XK27_09615 S reductase
EKEPFMFD_01325 7.1e-91 XK27_09620 S NADPH-dependent FMN reductase
EKEPFMFD_01326 2.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EKEPFMFD_01327 2.6e-213 frdC 1.3.5.4 C FAD binding domain
EKEPFMFD_01328 1.9e-224 yflS P Sodium:sulfate symporter transmembrane region
EKEPFMFD_01329 3.8e-162 mleR K LysR family transcriptional regulator
EKEPFMFD_01330 3.2e-253 yjjP S Putative threonine/serine exporter
EKEPFMFD_01331 6.7e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
EKEPFMFD_01332 1.6e-188 I Alpha beta
EKEPFMFD_01333 3.1e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
EKEPFMFD_01334 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKEPFMFD_01336 5.1e-167 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EKEPFMFD_01337 9.8e-310 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
EKEPFMFD_01338 3.5e-137 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
EKEPFMFD_01339 1.7e-204 araR K Transcriptional regulator
EKEPFMFD_01340 1.3e-246 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EKEPFMFD_01341 8.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EKEPFMFD_01342 1.7e-112 S Domain of unknown function (DUF4811)
EKEPFMFD_01343 2.8e-266 lmrB EGP Major facilitator Superfamily
EKEPFMFD_01344 4.3e-74 merR K MerR HTH family regulatory protein
EKEPFMFD_01345 5.2e-59
EKEPFMFD_01346 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKEPFMFD_01347 1.8e-179 S CAAX protease self-immunity
EKEPFMFD_01348 4.9e-25 S CAAX protease self-immunity
EKEPFMFD_01349 1e-30 elaA S GNAT family
EKEPFMFD_01350 3.8e-84 usp1 T Belongs to the universal stress protein A family
EKEPFMFD_01351 1.1e-108 S VIT family
EKEPFMFD_01352 3.9e-58 S membrane
EKEPFMFD_01353 3.5e-46 S membrane
EKEPFMFD_01354 3.7e-75 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
EKEPFMFD_01355 6e-73 O OsmC-like protein
EKEPFMFD_01356 2.6e-74 K Transcriptional regulator
EKEPFMFD_01357 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
EKEPFMFD_01358 1.7e-106 proWZ P ABC transporter permease
EKEPFMFD_01359 3.2e-141 proV E ABC transporter, ATP-binding protein
EKEPFMFD_01360 1.3e-100 proW P ABC transporter, permease protein
EKEPFMFD_01361 4.8e-148 C Zinc-binding dehydrogenase
EKEPFMFD_01362 9e-195 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
EKEPFMFD_01363 1.4e-192 4.4.1.8 E Aminotransferase, class I
EKEPFMFD_01364 1.1e-172 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EKEPFMFD_01365 2.5e-200 xerS L Belongs to the 'phage' integrase family
EKEPFMFD_01366 1.2e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
EKEPFMFD_01367 2.2e-79 hmpT S ECF-type riboflavin transporter, S component
EKEPFMFD_01368 3.6e-165 1.1.1.346 C Aldo keto reductase
EKEPFMFD_01369 2e-158 S DUF218 domain
EKEPFMFD_01370 2.2e-11 S Uncharacterized protein conserved in bacteria (DUF2316)
EKEPFMFD_01371 6e-61 K Acetyltransferase (GNAT) domain
EKEPFMFD_01372 1.5e-160 I alpha/beta hydrolase fold
EKEPFMFD_01374 4.4e-123 sirR K iron dependent repressor
EKEPFMFD_01375 1.1e-29 cspA K Cold shock protein
EKEPFMFD_01376 6.5e-82 thrE S Putative threonine/serine exporter
EKEPFMFD_01377 1.4e-28 thrE S Putative threonine/serine exporter
EKEPFMFD_01378 6.9e-81 S Threonine/Serine exporter, ThrE
EKEPFMFD_01379 2.2e-114 lssY 3.6.1.27 I phosphatase
EKEPFMFD_01380 1.2e-154 I alpha/beta hydrolase fold
EKEPFMFD_01382 9.6e-267 lysP E amino acid
EKEPFMFD_01383 2.3e-116 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
EKEPFMFD_01389 8.3e-89 IQ reductase
EKEPFMFD_01390 4.2e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EKEPFMFD_01391 3e-53 S ABC-type cobalt transport system, permease component
EKEPFMFD_01392 1.5e-70 thiW S Thiamine-precursor transporter protein (ThiW)
EKEPFMFD_01393 6.4e-55 rmeB K transcriptional regulator, MerR family
EKEPFMFD_01394 2.9e-111 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
EKEPFMFD_01396 1.9e-10 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
EKEPFMFD_01397 6e-120 J 2'-5' RNA ligase superfamily
EKEPFMFD_01398 8.2e-131 XK27_07210 6.1.1.6 S B3 4 domain
EKEPFMFD_01399 1.1e-192 adhP 1.1.1.1 C alcohol dehydrogenase
EKEPFMFD_01400 5.5e-65 M repeat protein
EKEPFMFD_01401 2.8e-09
EKEPFMFD_01402 8.4e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
EKEPFMFD_01403 1.6e-141 yueF S AI-2E family transporter
EKEPFMFD_01404 8.5e-163 ykoT GT2 M Glycosyl transferase family 2
EKEPFMFD_01405 8.5e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EKEPFMFD_01406 3.7e-95 M transferase activity, transferring glycosyl groups
EKEPFMFD_01407 1.6e-102 glfT1 1.1.1.133 S Glycosyltransferase like family 2
EKEPFMFD_01408 3.1e-83 S Bacterial membrane protein, YfhO
EKEPFMFD_01409 2.6e-169 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EKEPFMFD_01410 2.3e-63 gntR1 K Transcriptional regulator, GntR family
EKEPFMFD_01411 5.2e-156 V ABC transporter, ATP-binding protein
EKEPFMFD_01412 3e-13
EKEPFMFD_01413 1.8e-34 S CRISPR-associated protein (Cas_Csn2)
EKEPFMFD_01414 8.4e-35 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EKEPFMFD_01415 6.6e-93 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EKEPFMFD_01416 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EKEPFMFD_01417 3.5e-23 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKEPFMFD_01418 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKEPFMFD_01419 6.2e-140 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EKEPFMFD_01420 2.7e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EKEPFMFD_01421 6.2e-103 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EKEPFMFD_01422 4.9e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EKEPFMFD_01423 2.5e-69 psiE S Phosphate-starvation-inducible E
EKEPFMFD_01424 1.5e-37 V CAAX protease self-immunity
EKEPFMFD_01425 4.4e-49 tnp L MULE transposase domain
EKEPFMFD_01445 1e-15 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EKEPFMFD_01446 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EKEPFMFD_01447 2.6e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EKEPFMFD_01448 3.8e-198 coiA 3.6.4.12 S Competence protein
EKEPFMFD_01449 3.9e-113 yjbH Q Thioredoxin
EKEPFMFD_01450 6.2e-117 yjbM 2.7.6.5 S RelA SpoT domain protein
EKEPFMFD_01451 8.6e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKEPFMFD_01452 7.2e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
EKEPFMFD_01453 3.7e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
EKEPFMFD_01454 1e-159 rrmA 2.1.1.187 H Methyltransferase
EKEPFMFD_01455 3.3e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EKEPFMFD_01456 1.6e-77 ftsK D Belongs to the FtsK SpoIIIE SftA family
EKEPFMFD_01457 4.1e-304 ftsK D Belongs to the FtsK SpoIIIE SftA family
EKEPFMFD_01458 1.6e-07 S Protein of unknown function (DUF4044)
EKEPFMFD_01459 1.1e-56
EKEPFMFD_01469 2.3e-24 K Bacterial regulatory proteins, tetR family
EKEPFMFD_01471 1.5e-141 ET Bacterial periplasmic substrate-binding proteins
EKEPFMFD_01472 4.5e-110 XK27_05795 P ABC transporter permease
EKEPFMFD_01473 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EKEPFMFD_01474 1.2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EKEPFMFD_01475 1.9e-158 sufD O Uncharacterized protein family (UPF0051)
EKEPFMFD_01476 4.6e-236 F Permease
EKEPFMFD_01477 2.1e-199 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
EKEPFMFD_01478 3.3e-43 lytE M LysM domain protein
EKEPFMFD_01479 4e-84 ykhA 3.1.2.20 I Thioesterase superfamily
EKEPFMFD_01480 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
EKEPFMFD_01481 1.1e-93 K Transcriptional regulator, TetR family
EKEPFMFD_01482 1.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EKEPFMFD_01483 8e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EKEPFMFD_01484 3.1e-93 K Helix-turn-helix domain, rpiR family
EKEPFMFD_01485 2.1e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EKEPFMFD_01486 6.6e-220 lysP E amino acid
EKEPFMFD_01487 0.0 asnB 6.3.5.4 E Asparagine synthase
EKEPFMFD_01488 2.2e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EKEPFMFD_01489 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EKEPFMFD_01490 6.6e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EKEPFMFD_01491 1.4e-153 F DNA/RNA non-specific endonuclease
EKEPFMFD_01492 2.6e-64 L nuclease
EKEPFMFD_01493 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKEPFMFD_01494 5.9e-22
EKEPFMFD_01495 1.7e-100 L Belongs to the 'phage' integrase family
EKEPFMFD_01497 2e-85
EKEPFMFD_01498 1e-12 F Nucleoside 2-deoxyribosyltransferase
EKEPFMFD_01499 2.9e-44 F Nucleoside 2-deoxyribosyltransferase
EKEPFMFD_01500 1.6e-180 scrR3 K Transcriptional regulator, LacI family
EKEPFMFD_01501 8e-12
EKEPFMFD_01502 5.7e-116 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
EKEPFMFD_01503 0.0 asnB 6.3.5.4 E Aluminium induced protein
EKEPFMFD_01504 3.8e-50 S Sugar efflux transporter for intercellular exchange
EKEPFMFD_01505 8.9e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
EKEPFMFD_01506 1.8e-41 S Protein conserved in bacteria
EKEPFMFD_01507 1.1e-95 ywrO S Flavodoxin-like fold
EKEPFMFD_01508 4e-150 tesE Q hydratase
EKEPFMFD_01509 1.5e-186 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKEPFMFD_01510 1.2e-61 S Domain of unknown function (DUF4440)
EKEPFMFD_01511 2.3e-27 GM Glycosyltransferase like family 2
EKEPFMFD_01512 9.4e-61 M Glycosyltransferase like family 2
EKEPFMFD_01513 1.1e-121 S Polysaccharide biosynthesis protein
EKEPFMFD_01514 5.5e-84 tagB 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
EKEPFMFD_01515 1.6e-91 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
EKEPFMFD_01516 9.3e-107 4.2.1.46 GM Male sterility protein
EKEPFMFD_01517 6.3e-93 S Cupin superfamily (DUF985)
EKEPFMFD_01518 2.3e-122 K response regulator
EKEPFMFD_01519 8e-205 hpk31 2.7.13.3 T Histidine kinase
EKEPFMFD_01520 9.8e-160 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EKEPFMFD_01521 5e-138 azlC E AzlC protein
EKEPFMFD_01522 9.9e-60 azlD S branched-chain amino acid
EKEPFMFD_01523 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKEPFMFD_01524 2.7e-244 fucP G Major Facilitator Superfamily
EKEPFMFD_01525 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EKEPFMFD_01526 2.2e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKEPFMFD_01527 1.6e-169 deoR K sugar-binding domain protein
EKEPFMFD_01528 4.9e-114 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EKEPFMFD_01529 5.8e-199 S Domain of unknown function (DUF4432)
EKEPFMFD_01530 1.2e-174 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKEPFMFD_01531 1.7e-260 G PTS system Galactitol-specific IIC component
EKEPFMFD_01532 1.1e-169 K helix_turn _helix lactose operon repressor
EKEPFMFD_01533 1.5e-166 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EKEPFMFD_01534 7.1e-173 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EKEPFMFD_01535 9.1e-127 lysC 2.7.2.4 E Belongs to the aspartokinase family
EKEPFMFD_01536 4.9e-117 lysC 2.7.2.4 E Belongs to the aspartokinase family
EKEPFMFD_01537 5.9e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EKEPFMFD_01538 3.3e-71 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EKEPFMFD_01539 1.9e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EKEPFMFD_01540 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKEPFMFD_01541 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EKEPFMFD_01542 1.9e-217 patA 2.6.1.1 E Aminotransferase
EKEPFMFD_01543 1.3e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EKEPFMFD_01544 5.7e-226 ktrB P Potassium uptake protein
EKEPFMFD_01545 1.7e-53 ktrA P domain protein
EKEPFMFD_01546 4.7e-48 ktrA P domain protein
EKEPFMFD_01547 1.5e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
EKEPFMFD_01548 1.3e-18 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EKEPFMFD_01549 1.6e-111 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EKEPFMFD_01550 7.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EKEPFMFD_01552 5.8e-100 dnaE 2.7.7.7 L DNA polymerase
EKEPFMFD_01553 0.0 dnaE 2.7.7.7 L DNA polymerase
EKEPFMFD_01554 9.1e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EKEPFMFD_01555 6.1e-168 cvfB S S1 domain
EKEPFMFD_01556 1.6e-157 xerD D recombinase XerD
EKEPFMFD_01557 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKEPFMFD_01558 8.7e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EKEPFMFD_01559 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EKEPFMFD_01560 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EKEPFMFD_01561 1.2e-79 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EKEPFMFD_01562 1.2e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
EKEPFMFD_01563 1e-276 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
EKEPFMFD_01564 4.2e-29 M Lysin motif
EKEPFMFD_01565 3.2e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EKEPFMFD_01566 8.3e-208 rpsA 1.17.7.4 J Ribosomal protein S1
EKEPFMFD_01567 1.8e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EKEPFMFD_01568 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EKEPFMFD_01569 5e-232 S Tetratricopeptide repeat protein
EKEPFMFD_01570 3.3e-155 xerD L Phage integrase, N-terminal SAM-like domain
EKEPFMFD_01571 2.1e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EKEPFMFD_01572 0.0 yfmR S ABC transporter, ATP-binding protein
EKEPFMFD_01573 2.3e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EKEPFMFD_01574 6.1e-93 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EKEPFMFD_01575 7.7e-109 hlyIII S protein, hemolysin III
EKEPFMFD_01576 7.6e-152 DegV S EDD domain protein, DegV family
EKEPFMFD_01577 5.2e-215 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
EKEPFMFD_01578 2.2e-108 cat S Bacterial transferase hexapeptide (six repeats)
EKEPFMFD_01579 1.3e-165 ypmR E lipolytic protein G-D-S-L family
EKEPFMFD_01580 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
EKEPFMFD_01581 3.1e-36 yozE S Belongs to the UPF0346 family
EKEPFMFD_01582 7.8e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EKEPFMFD_01583 2.3e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKEPFMFD_01584 2.9e-162 dprA LU DNA protecting protein DprA
EKEPFMFD_01585 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKEPFMFD_01586 2.4e-153 D DNA integration
EKEPFMFD_01587 9e-172 lacX 5.1.3.3 G Aldose 1-epimerase
EKEPFMFD_01588 4.7e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EKEPFMFD_01589 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EKEPFMFD_01590 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EKEPFMFD_01591 5.8e-94 S Protein of unknown function (DUF1440)
EKEPFMFD_01592 8.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
EKEPFMFD_01593 1.5e-70 yqkB S Belongs to the HesB IscA family
EKEPFMFD_01594 5.5e-74 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EKEPFMFD_01595 6.3e-75 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
EKEPFMFD_01596 8.4e-81 yebR 1.8.4.14 T GAF domain-containing protein
EKEPFMFD_01597 2e-242 U Belongs to the purine-cytosine permease (2.A.39) family
EKEPFMFD_01598 4.4e-241 codA 3.5.4.1 F cytosine deaminase
EKEPFMFD_01599 0.0 oppD EP Psort location Cytoplasmic, score
EKEPFMFD_01601 2.4e-253 rarA L recombination factor protein RarA
EKEPFMFD_01602 4.5e-41 S Protein of unknown function (DUF554)
EKEPFMFD_01603 1.8e-40 S Protein of unknown function (DUF554)
EKEPFMFD_01604 3.3e-242 yhjX P Major Facilitator Superfamily
EKEPFMFD_01605 2.6e-65 mutR K Transcriptional activator, Rgg GadR MutR family
EKEPFMFD_01606 5e-229 ndh 1.6.99.3 C NADH dehydrogenase
EKEPFMFD_01607 1.7e-117 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
EKEPFMFD_01608 2.1e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EKEPFMFD_01609 9.3e-56 S Flavodoxin
EKEPFMFD_01610 5.8e-64 moaE 2.8.1.12 H MoaE protein
EKEPFMFD_01611 2.4e-34 moaD 2.8.1.12 H ThiS family
EKEPFMFD_01612 2.3e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EKEPFMFD_01613 3.4e-214 narK P Major Facilitator Superfamily
EKEPFMFD_01614 7.5e-58 yitW S Iron-sulfur cluster assembly protein
EKEPFMFD_01615 5.5e-161 hipB K Helix-turn-helix
EKEPFMFD_01616 1.6e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EKEPFMFD_01618 1.9e-148 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
EKEPFMFD_01619 1.1e-124 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
EKEPFMFD_01620 5.4e-204 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EKEPFMFD_01621 1.1e-139 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKEPFMFD_01622 1.2e-208 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EKEPFMFD_01623 5.9e-52
EKEPFMFD_01624 5.8e-97 tag 3.2.2.20 L glycosylase
EKEPFMFD_01625 1.5e-248 EGP Major facilitator Superfamily
EKEPFMFD_01626 2.1e-84 perR P Belongs to the Fur family
EKEPFMFD_01627 1.6e-247 cycA E Amino acid permease
EKEPFMFD_01628 4e-22
EKEPFMFD_01630 3.5e-159 MA20_14895 S Conserved hypothetical protein 698
EKEPFMFD_01631 2.3e-162 K LysR substrate binding domain
EKEPFMFD_01632 9e-133 manA 5.3.1.8 G mannose-6-phosphate isomerase
EKEPFMFD_01633 8.1e-146 yitS S EDD domain protein, DegV family
EKEPFMFD_01634 1.6e-88 racA K Domain of unknown function (DUF1836)
EKEPFMFD_01635 1.6e-179 yfeX P Peroxidase
EKEPFMFD_01636 1e-179 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
EKEPFMFD_01637 3.5e-122 manY G PTS system
EKEPFMFD_01638 5.9e-166 manN G system, mannose fructose sorbose family IID component
EKEPFMFD_01639 1.5e-55 S Domain of unknown function (DUF956)
EKEPFMFD_01641 2e-25 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EKEPFMFD_01642 6.4e-154 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EKEPFMFD_01643 1.7e-126 epsB M biosynthesis protein
EKEPFMFD_01644 7.5e-119 ywqD 2.7.10.1 D Capsular exopolysaccharide family
EKEPFMFD_01645 1.4e-141 ywqE 3.1.3.48 GM PHP domain protein
EKEPFMFD_01646 1.1e-86 capM M Bacterial sugar transferase
EKEPFMFD_01647 1.4e-82 GT4 G Glycosyl transferase 4-like
EKEPFMFD_01648 9.2e-67 M Domain of unknown function (DUF4422)
EKEPFMFD_01649 7.2e-68 MA20_43635 M Capsular polysaccharide synthesis protein
EKEPFMFD_01650 1.6e-41 S glycosyl transferase family 2
EKEPFMFD_01652 2e-278 mntH P H( )-stimulated, divalent metal cation uptake system
EKEPFMFD_01653 9.3e-189 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
EKEPFMFD_01654 1.1e-107 ygfC K Bacterial regulatory proteins, tetR family
EKEPFMFD_01655 1.5e-157 hrtB V ABC transporter permease
EKEPFMFD_01656 1.8e-122 devA 3.6.3.25 V ABC transporter, ATP-binding protein
EKEPFMFD_01657 7e-75 argR K Regulates arginine biosynthesis genes
EKEPFMFD_01658 2.6e-46 czrA K Transcriptional regulator, ArsR family
EKEPFMFD_01659 1.5e-164 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EKEPFMFD_01660 1.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EKEPFMFD_01661 6.1e-66 L Transposase
EKEPFMFD_01662 2e-61
EKEPFMFD_01663 2.5e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EKEPFMFD_01664 1.2e-60 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EKEPFMFD_01665 0.0 dnaK O Heat shock 70 kDa protein
EKEPFMFD_01666 5.4e-124 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EKEPFMFD_01667 2.1e-38 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EKEPFMFD_01668 1.5e-96 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EKEPFMFD_01669 1.2e-68 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EKEPFMFD_01671 3.8e-43 K Bacterial regulatory proteins, tetR family
EKEPFMFD_01672 1.5e-221 norB EGP Major Facilitator
EKEPFMFD_01674 1.4e-178 L helicase activity
EKEPFMFD_01675 9.5e-25 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EKEPFMFD_01677 7.6e-280 2.4.1.5 GH13 G Glycosyl hydrolase family 70
EKEPFMFD_01678 1.1e-111 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase
EKEPFMFD_01680 3.9e-16 tnp L MULE transposase domain
EKEPFMFD_01681 1.2e-203 EGP Major facilitator Superfamily
EKEPFMFD_01682 2.6e-134 ycsG P Natural resistance-associated macrophage protein
EKEPFMFD_01683 5.5e-65
EKEPFMFD_01685 2.9e-190 ydaM M Glycosyl transferase family group 2
EKEPFMFD_01686 1.1e-126 G Glycosyl hydrolases family 8
EKEPFMFD_01687 2.1e-138 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
EKEPFMFD_01688 4.6e-177 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKEPFMFD_01689 2.3e-08 sucD 6.2.1.5 C CoA-ligase
EKEPFMFD_01690 4.8e-166 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
EKEPFMFD_01691 1e-35 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
EKEPFMFD_01692 9.4e-27 S Protein of unknown function (DUF2877)
EKEPFMFD_01693 2.2e-76 arcC 2.7.2.2 E Amino acid kinase family
EKEPFMFD_01694 2.1e-25 arcC 2.7.2.2 E Amino acid kinase family
EKEPFMFD_01695 3.9e-173 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EKEPFMFD_01696 8.8e-124 C nitroreductase
EKEPFMFD_01697 1.6e-134 E GDSL-like Lipase/Acylhydrolase family
EKEPFMFD_01698 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
EKEPFMFD_01699 8.1e-196 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
EKEPFMFD_01700 0.0 pepN 3.4.11.2 E aminopeptidase
EKEPFMFD_01701 5.6e-26 S Hexapeptide repeat of succinyl-transferase
EKEPFMFD_01702 2.1e-125 S Oxidoreductase, aldo keto reductase family protein
EKEPFMFD_01703 7.5e-67 akr5f 1.1.1.346 S reductase
EKEPFMFD_01704 1.8e-162 K Transcriptional regulator
EKEPFMFD_01705 2.3e-24 phaG GT1 I carboxylic ester hydrolase activity
EKEPFMFD_01706 2.8e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EKEPFMFD_01708 9e-153 metQ_4 P Belongs to the nlpA lipoprotein family
EKEPFMFD_01709 2.2e-202 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EKEPFMFD_01710 0.0 helD 3.6.4.12 L DNA helicase
EKEPFMFD_01711 2.8e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EKEPFMFD_01712 4.3e-215 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EKEPFMFD_01713 2.5e-186
EKEPFMFD_01714 5.5e-124 cobB K SIR2 family
EKEPFMFD_01715 1.9e-209 norA EGP Major facilitator Superfamily
EKEPFMFD_01716 4e-161 yunF F Protein of unknown function DUF72
EKEPFMFD_01717 1.1e-266 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKEPFMFD_01718 1.6e-115 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKEPFMFD_01719 3.4e-146 tatD L hydrolase, TatD family
EKEPFMFD_01720 5.6e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EKEPFMFD_01721 8.4e-67 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EKEPFMFD_01722 1.8e-72 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EKEPFMFD_01723 6e-157 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EKEPFMFD_01724 9.3e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
EKEPFMFD_01725 7.3e-92 fhuC P ABC transporter
EKEPFMFD_01726 3.2e-128 znuB U ABC 3 transport family
EKEPFMFD_01727 6.4e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
EKEPFMFD_01728 6.9e-203 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EKEPFMFD_01729 5e-94 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EKEPFMFD_01730 4.1e-66 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EKEPFMFD_01731 2e-31
EKEPFMFD_01732 3.8e-140 yxeH S hydrolase
EKEPFMFD_01733 5.3e-264 ywfO S HD domain protein
EKEPFMFD_01734 3.2e-74 ywiB S Domain of unknown function (DUF1934)
EKEPFMFD_01735 2.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EKEPFMFD_01736 5.8e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EKEPFMFD_01737 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKEPFMFD_01738 1.7e-40 rpmE2 J Ribosomal protein L31
EKEPFMFD_01739 2.7e-121 mdtG EGP Major facilitator Superfamily
EKEPFMFD_01740 4.6e-21 mdtG EGP Major facilitator Superfamily
EKEPFMFD_01741 3.6e-33 srtA 3.4.22.70 M sortase family
EKEPFMFD_01742 1.3e-76 srtA 3.4.22.70 M sortase family
EKEPFMFD_01743 1.4e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EKEPFMFD_01744 2.5e-87 lemA S LemA family
EKEPFMFD_01745 5.4e-156 htpX O Belongs to the peptidase M48B family
EKEPFMFD_01746 2.3e-259 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EKEPFMFD_01747 9.6e-150 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EKEPFMFD_01748 6.2e-90 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EKEPFMFD_01749 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EKEPFMFD_01750 2.6e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKEPFMFD_01751 7.3e-56 L Toxic component of a toxin-antitoxin (TA) module
EKEPFMFD_01752 2e-112 S (CBS) domain
EKEPFMFD_01753 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EKEPFMFD_01754 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EKEPFMFD_01755 1.6e-39 yabO J S4 domain protein
EKEPFMFD_01756 1.5e-56 divIC D Septum formation initiator
EKEPFMFD_01757 2.5e-86 yabR J RNA binding
EKEPFMFD_01758 6.5e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EKEPFMFD_01759 3.9e-66 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EKEPFMFD_01760 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKEPFMFD_01761 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EKEPFMFD_01762 9.4e-123 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EKEPFMFD_01763 3e-27 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EKEPFMFD_01764 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EKEPFMFD_01766 5.4e-41 L Helix-turn-helix domain
EKEPFMFD_01767 2.5e-242 ganB 3.2.1.89 G arabinogalactan
EKEPFMFD_01768 4.7e-29 S Domain of unknown function (DUF4767)
EKEPFMFD_01769 1.9e-44 S Tautomerase enzyme
EKEPFMFD_01770 3.4e-12 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
EKEPFMFD_01771 3.9e-119 pnb C nitroreductase
EKEPFMFD_01772 6.5e-81 S Alpha/beta hydrolase family
EKEPFMFD_01773 1.6e-18 S Alpha/beta hydrolase family
EKEPFMFD_01774 4.4e-49 tnp L MULE transposase domain
EKEPFMFD_01775 2.1e-13 L Transposase and inactivated derivatives IS30 family
EKEPFMFD_01776 3.8e-151 glcU U sugar transport
EKEPFMFD_01777 1.3e-250 yclK 2.7.13.3 T Histidine kinase
EKEPFMFD_01778 2.8e-131 K response regulator
EKEPFMFD_01779 1.3e-138 L helicase activity
EKEPFMFD_01780 2.5e-215 K DNA binding
EKEPFMFD_01781 5.9e-155 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
EKEPFMFD_01782 9.8e-77
EKEPFMFD_01783 4.4e-49 tnp L MULE transposase domain
EKEPFMFD_01784 1.3e-38 L Transposase
EKEPFMFD_01785 4e-15 K helix_turn_helix multiple antibiotic resistance protein
EKEPFMFD_01786 6.4e-27 3.4.21.72 M Bacterial Ig-like domain (group 3)
EKEPFMFD_01787 1.3e-34 ypaA S Protein of unknown function (DUF1304)
EKEPFMFD_01788 3.2e-48 L PFAM Integrase catalytic region
EKEPFMFD_01789 1.8e-88
EKEPFMFD_01790 2.1e-22 S Small integral membrane protein (DUF2273)
EKEPFMFD_01791 4.4e-76 S Asp23 family, cell envelope-related function
EKEPFMFD_01792 1.3e-11 S Transglycosylase associated protein
EKEPFMFD_01793 1.2e-14
EKEPFMFD_01794 1.5e-26 EGP Major Facilitator Superfamily
EKEPFMFD_01795 9.2e-26 EGP Major Facilitator Superfamily
EKEPFMFD_01796 6.4e-38 EGP Major Facilitator Superfamily
EKEPFMFD_01797 5.1e-215 L transposase, IS605 OrfB family
EKEPFMFD_01798 4.1e-56 S Sel1-like repeats.
EKEPFMFD_01799 1.8e-62 yjbR S YjbR
EKEPFMFD_01800 9.2e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EKEPFMFD_01801 4.4e-38 S Domain of unknown function (DUF3841)
EKEPFMFD_01802 4.5e-112 licT K CAT RNA binding domain
EKEPFMFD_01803 4.7e-269 bglP 2.7.1.211 G phosphotransferase system
EKEPFMFD_01804 1.4e-262 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EKEPFMFD_01805 7.2e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
EKEPFMFD_01806 1e-22 D mRNA cleavage
EKEPFMFD_01807 4.4e-171 S Phosphotransferase system, EIIC
EKEPFMFD_01809 5.1e-142 S Oxidoreductase family, NAD-binding Rossmann fold
EKEPFMFD_01811 2.1e-191 nhaC C Na H antiporter NhaC
EKEPFMFD_01813 1e-73 ddaH 3.5.3.18 E Amidinotransferase
EKEPFMFD_01814 1.6e-88 S Aminoacyl-tRNA editing domain
EKEPFMFD_01815 4.9e-306 mco Q Multicopper oxidase
EKEPFMFD_01816 9.1e-50 K 2 iron, 2 sulfur cluster binding
EKEPFMFD_01817 1.1e-68 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
EKEPFMFD_01818 4.3e-113 Q Methyltransferase domain
EKEPFMFD_01820 3.3e-101 S CAAX protease self-immunity
EKEPFMFD_01821 2.9e-93 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKEPFMFD_01822 5.4e-11 fsr EGP Major Facilitator Superfamily
EKEPFMFD_01823 1.4e-81 fsr EGP Major Facilitator Superfamily
EKEPFMFD_01824 4.7e-64 K helix_turn_helix, arabinose operon control protein
EKEPFMFD_01825 8.8e-101 K helix_turn_helix multiple antibiotic resistance protein
EKEPFMFD_01826 4e-181 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EKEPFMFD_01827 1e-104
EKEPFMFD_01828 2.4e-83 dps P Belongs to the Dps family
EKEPFMFD_01829 2e-302 ybiT S ABC transporter, ATP-binding protein
EKEPFMFD_01831 8.7e-33 yneR S Belongs to the HesB IscA family
EKEPFMFD_01832 1.7e-134 S NADPH-dependent FMN reductase
EKEPFMFD_01833 6.9e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EKEPFMFD_01834 1.3e-157 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EKEPFMFD_01835 1.3e-102 yvdD 3.2.2.10 S Belongs to the LOG family
EKEPFMFD_01836 4.9e-63 S Domain of unknown function (DUF4828)
EKEPFMFD_01837 1.3e-190 mocA S Oxidoreductase
EKEPFMFD_01838 1.7e-230 yfmL 3.6.4.13 L DEAD DEAH box helicase
EKEPFMFD_01840 3e-75 gtcA S Teichoic acid glycosylation protein
EKEPFMFD_01841 8.5e-78 fld C Flavodoxin
EKEPFMFD_01842 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
EKEPFMFD_01843 0.0 XK27_08315 M Sulfatase
EKEPFMFD_01844 7.8e-139 yihY S Belongs to the UPF0761 family
EKEPFMFD_01845 3.8e-31 S Protein of unknown function (DUF2922)
EKEPFMFD_01846 1.3e-07
EKEPFMFD_01847 5.1e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
EKEPFMFD_01848 1.1e-118 rfbP M Bacterial sugar transferase
EKEPFMFD_01849 5.1e-147 cps1D M Domain of unknown function (DUF4422)
EKEPFMFD_01850 4.2e-95 cps3F
EKEPFMFD_01851 4.5e-45 M biosynthesis protein
EKEPFMFD_01852 2.1e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
EKEPFMFD_01853 4.2e-203 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
EKEPFMFD_01854 9.7e-72 S enterobacterial common antigen metabolic process
EKEPFMFD_01855 2.5e-64 acmD M repeat protein
EKEPFMFD_01856 7.4e-76 S Psort location CytoplasmicMembrane, score
EKEPFMFD_01857 8.6e-243 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EKEPFMFD_01858 3.9e-134 L PFAM transposase, IS4 family protein
EKEPFMFD_01861 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
EKEPFMFD_01862 2.1e-114 L Integrase core domain
EKEPFMFD_01863 1.6e-166 scrR K Transcriptional regulator, LacI family
EKEPFMFD_01864 9.5e-26
EKEPFMFD_01865 1.7e-100
EKEPFMFD_01866 2.3e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EKEPFMFD_01867 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
EKEPFMFD_01868 1.3e-54
EKEPFMFD_01869 1.4e-124 yrkL S Flavodoxin-like fold
EKEPFMFD_01871 2e-64 yeaO S Protein of unknown function, DUF488
EKEPFMFD_01872 1.5e-85 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
EKEPFMFD_01873 4.5e-200 3.1.3.1 S associated with various cellular activities
EKEPFMFD_01874 8.7e-210 S Putative metallopeptidase domain
EKEPFMFD_01875 1e-44
EKEPFMFD_01876 1.8e-229 pbuG S permease
EKEPFMFD_01877 0.0 pepO 3.4.24.71 O Peptidase family M13
EKEPFMFD_01878 5e-90 ymdB S Macro domain protein
EKEPFMFD_01879 5e-145 pnuC H nicotinamide mononucleotide transporter
EKEPFMFD_01880 7.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EKEPFMFD_01881 7.6e-169 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKEPFMFD_01882 2e-52
EKEPFMFD_01883 1.4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EKEPFMFD_01884 6.3e-120 tcyB U Binding-protein-dependent transport system inner membrane component
EKEPFMFD_01885 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EKEPFMFD_01886 6.9e-36
EKEPFMFD_01887 1.8e-95 yxkA S Phosphatidylethanolamine-binding protein
EKEPFMFD_01888 8.8e-75 ptp3 3.1.3.48 T Tyrosine phosphatase family
EKEPFMFD_01889 2.4e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
EKEPFMFD_01890 3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EKEPFMFD_01891 1.9e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EKEPFMFD_01892 4.6e-180 galR K Transcriptional regulator
EKEPFMFD_01893 0.0 rafA 3.2.1.22 G alpha-galactosidase
EKEPFMFD_01894 2.1e-277 lacS G Transporter
EKEPFMFD_01895 2e-62 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EKEPFMFD_01896 7.7e-42 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EKEPFMFD_01897 3.1e-124 S Membrane
EKEPFMFD_01898 3.2e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKEPFMFD_01899 0.0 pepF E oligoendopeptidase F
EKEPFMFD_01900 4.7e-177 K helix_turn _helix lactose operon repressor
EKEPFMFD_01901 3.1e-101 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKEPFMFD_01902 9.3e-141 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EKEPFMFD_01903 2.7e-60 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
EKEPFMFD_01904 4.8e-158 C C4-dicarboxylate transmembrane transporter activity
EKEPFMFD_01905 2.9e-62 K AsnC family
EKEPFMFD_01906 6.7e-81 uspA T universal stress protein
EKEPFMFD_01907 1.1e-270 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EKEPFMFD_01908 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EKEPFMFD_01909 3.3e-206 yeaN P Transporter, major facilitator family protein
EKEPFMFD_01910 6.5e-75 S 3-demethylubiquinone-9 3-methyltransferase
EKEPFMFD_01911 5.4e-83 nrdI F Belongs to the NrdI family
EKEPFMFD_01912 3.5e-247 yhdP S Transporter associated domain
EKEPFMFD_01913 3e-90 GM epimerase
EKEPFMFD_01914 2.4e-84 M1-874 K Domain of unknown function (DUF1836)
EKEPFMFD_01915 4.1e-155 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
EKEPFMFD_01916 8.7e-265 pipD E Dipeptidase
EKEPFMFD_01917 2.7e-129
EKEPFMFD_01918 2.2e-54 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EKEPFMFD_01919 3.5e-129 gntR K UbiC transcription regulator-associated domain protein
EKEPFMFD_01920 6.3e-148 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
EKEPFMFD_01921 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
EKEPFMFD_01922 2.5e-102 dedA S SNARE-like domain protein
EKEPFMFD_01923 7.5e-25 S Protein of unknown function (DUF1461)
EKEPFMFD_01924 7.3e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EKEPFMFD_01925 5.6e-92 yutD S Protein of unknown function (DUF1027)
EKEPFMFD_01926 6.1e-106 S Calcineurin-like phosphoesterase
EKEPFMFD_01927 9.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EKEPFMFD_01928 2.8e-157 ytxK 2.1.1.72 L N-6 DNA Methylase
EKEPFMFD_01930 1.3e-14
EKEPFMFD_01933 1.1e-47 comGC U competence protein ComGC
EKEPFMFD_01934 2.5e-157 comGB NU type II secretion system
EKEPFMFD_01935 8.6e-176 comGA NU Type II IV secretion system protein
EKEPFMFD_01936 2.4e-175 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
EKEPFMFD_01937 2.4e-140 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
EKEPFMFD_01938 1.9e-80 mltD CBM50 M PFAM NLP P60 protein
EKEPFMFD_01939 3.7e-134 yebC K Transcriptional regulatory protein
EKEPFMFD_01940 4.5e-75
EKEPFMFD_01941 1e-182 ccpA K catabolite control protein A
EKEPFMFD_01942 1e-212 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EKEPFMFD_01943 1.7e-67
EKEPFMFD_01944 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EKEPFMFD_01945 5.8e-155 ykuT M mechanosensitive ion channel
EKEPFMFD_01946 7.7e-147 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
EKEPFMFD_01947 8.8e-95 S Phosphoesterase
EKEPFMFD_01948 1.5e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EKEPFMFD_01949 1.8e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EKEPFMFD_01950 8.7e-93 yslB S Protein of unknown function (DUF2507)
EKEPFMFD_01951 3.8e-224 clcA_2 P Chloride transporter, ClC family
EKEPFMFD_01952 3.9e-53 trxA O Belongs to the thioredoxin family
EKEPFMFD_01953 6.6e-78 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EKEPFMFD_01954 1.9e-262 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EKEPFMFD_01955 1.1e-27 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EKEPFMFD_01956 1.4e-90 cvpA S Colicin V production protein
EKEPFMFD_01957 4.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKEPFMFD_01958 5.7e-33 yrzB S Belongs to the UPF0473 family
EKEPFMFD_01959 1.6e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EKEPFMFD_01960 1.2e-42 yrzL S Belongs to the UPF0297 family
EKEPFMFD_01961 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EKEPFMFD_01962 8.6e-141 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EKEPFMFD_01963 3.6e-67 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EKEPFMFD_01964 2e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
EKEPFMFD_01965 9.3e-42 yajC U Preprotein translocase
EKEPFMFD_01966 1.7e-173 2.4.2.29 F queuine tRNA-ribosyltransferase activity
EKEPFMFD_01967 5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EKEPFMFD_01968 5.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EKEPFMFD_01969 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EKEPFMFD_01970 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EKEPFMFD_01971 3.6e-120 rny S Endoribonuclease that initiates mRNA decay
EKEPFMFD_01972 2.3e-63 rny S Endoribonuclease that initiates mRNA decay
EKEPFMFD_01973 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EKEPFMFD_01974 1.1e-226 cinA 3.5.1.42 S Belongs to the CinA family
EKEPFMFD_01975 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKEPFMFD_01976 3.2e-96 ymfM S Helix-turn-helix domain
EKEPFMFD_01977 1.8e-30 ymfH S Peptidase M16
EKEPFMFD_01978 5.7e-200 ymfH S Peptidase M16
EKEPFMFD_01979 4e-87 ymfF S Peptidase M16 inactive domain protein
EKEPFMFD_01980 1.9e-112 ymfF S Peptidase M16 inactive domain protein
EKEPFMFD_01981 3.5e-160 aatB ET ABC transporter substrate-binding protein
EKEPFMFD_01982 7.4e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EKEPFMFD_01983 6.7e-108 glnP P ABC transporter permease
EKEPFMFD_01984 2.5e-92 mreD M rod shape-determining protein MreD
EKEPFMFD_01985 2.4e-145 mreC M Involved in formation and maintenance of cell shape
EKEPFMFD_01986 1.9e-181 mreB D cell shape determining protein MreB
EKEPFMFD_01987 9.4e-115 radC L DNA repair protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)