ORF_ID e_value Gene_name EC_number CAZy COGs Description
KCIBCFLH_00001 4e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KCIBCFLH_00002 4.7e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KCIBCFLH_00003 1.2e-32 yaaA S S4 domain
KCIBCFLH_00004 1.6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCIBCFLH_00005 7.3e-11 yaaB S Domain of unknown function (DUF370)
KCIBCFLH_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCIBCFLH_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCIBCFLH_00008 8.9e-198 M1-161 T HD domain
KCIBCFLH_00009 4.3e-42 S COG NOG14552 non supervised orthologous group
KCIBCFLH_00012 1.7e-41
KCIBCFLH_00013 1.9e-35 csfB S Inhibitor of sigma-G Gin
KCIBCFLH_00014 1.8e-289 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KCIBCFLH_00015 2e-120 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCIBCFLH_00016 9.8e-55 yaaQ S protein conserved in bacteria
KCIBCFLH_00017 1.8e-72 yaaR S protein conserved in bacteria
KCIBCFLH_00018 4.3e-186 holB 2.7.7.7 L DNA polymerase III
KCIBCFLH_00019 1.7e-148 yaaT S stage 0 sporulation protein
KCIBCFLH_00020 4.5e-67 yabA L Involved in initiation control of chromosome replication
KCIBCFLH_00021 2.2e-139 yabB 2.1.1.223 S Conserved hypothetical protein 95
KCIBCFLH_00022 1.6e-48 yazA L endonuclease containing a URI domain
KCIBCFLH_00023 1.8e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KCIBCFLH_00024 1.2e-56 abrB K COG2002 Regulators of stationary sporulation gene expression
KCIBCFLH_00025 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCIBCFLH_00026 1e-147 tatD L hydrolase, TatD
KCIBCFLH_00027 8.5e-105 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KCIBCFLH_00028 2.3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KCIBCFLH_00029 8.7e-167 yabG S peptidase
KCIBCFLH_00030 2.4e-37 veg S protein conserved in bacteria
KCIBCFLH_00031 2.2e-34 sspF S DNA topological change
KCIBCFLH_00032 1.6e-47 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KCIBCFLH_00033 4.4e-64 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KCIBCFLH_00034 2.9e-154 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KCIBCFLH_00035 3.2e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KCIBCFLH_00036 3.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KCIBCFLH_00038 2.9e-224 S Psort location CytoplasmicMembrane, score
KCIBCFLH_00039 2.1e-39 V Abc transporter
KCIBCFLH_00040 1e-81
KCIBCFLH_00041 2.3e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCIBCFLH_00042 3.6e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCIBCFLH_00043 2.4e-110 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KCIBCFLH_00044 1.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KCIBCFLH_00045 1.7e-37 yabK S Peptide ABC transporter permease
KCIBCFLH_00046 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCIBCFLH_00047 6.2e-91 spoVT K stage V sporulation protein
KCIBCFLH_00048 7.9e-291 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KCIBCFLH_00049 1.1e-195 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KCIBCFLH_00050 1.1e-41 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KCIBCFLH_00051 4.7e-51 yabP S Sporulation protein YabP
KCIBCFLH_00052 3.7e-111 yabQ S spore cortex biosynthesis protein
KCIBCFLH_00053 5.5e-60 divIC D Septum formation initiator
KCIBCFLH_00054 2.8e-54 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KCIBCFLH_00056 3.4e-150 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KCIBCFLH_00057 5.5e-300 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KCIBCFLH_00058 1.9e-108 yabS S protein containing a von Willebrand factor type A (vWA) domain
KCIBCFLH_00059 2.2e-142 KLT serine threonine protein kinase
KCIBCFLH_00060 4.3e-08 KLT serine threonine protein kinase
KCIBCFLH_00061 6.4e-221 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KCIBCFLH_00062 3.7e-26 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KCIBCFLH_00063 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KCIBCFLH_00064 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCIBCFLH_00065 3.8e-142 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KCIBCFLH_00066 3e-159 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCIBCFLH_00067 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KCIBCFLH_00068 1.3e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCIBCFLH_00069 4.2e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCIBCFLH_00070 1.6e-96 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCIBCFLH_00071 1e-284 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KCIBCFLH_00072 4.3e-42 S COG NOG14552 non supervised orthologous group
KCIBCFLH_00073 5.3e-43
KCIBCFLH_00076 1.6e-08
KCIBCFLH_00077 4e-08
KCIBCFLH_00081 4.3e-42 S COG NOG14552 non supervised orthologous group
KCIBCFLH_00082 5.3e-43
KCIBCFLH_00083 2.7e-182 yaaC S YaaC-like Protein
KCIBCFLH_00084 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KCIBCFLH_00085 3.2e-250 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCIBCFLH_00086 1.6e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KCIBCFLH_00087 4.4e-103 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KCIBCFLH_00088 2.9e-211 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KCIBCFLH_00089 2.9e-09
KCIBCFLH_00090 1.3e-125 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KCIBCFLH_00091 5.4e-118 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KCIBCFLH_00092 2.4e-250 yaaH M Glycoside Hydrolase Family
KCIBCFLH_00093 1e-87 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KCIBCFLH_00094 7e-311 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCIBCFLH_00095 1.3e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KCIBCFLH_00096 1.5e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KCIBCFLH_00097 6.9e-09 S Protein of unknown function (DUF2508)
KCIBCFLH_00098 5.7e-37 bofA S Sigma-K factor-processing regulatory protein BofA
KCIBCFLH_00099 1.6e-41 S COG NOG14552 non supervised orthologous group
KCIBCFLH_00102 1.7e-41
KCIBCFLH_00103 5.3e-44 S Protein of unknown function (DUF3969)
KCIBCFLH_00105 5.4e-75 ctsR K Belongs to the CtsR family
KCIBCFLH_00106 1.3e-99 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KCIBCFLH_00107 8e-191 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KCIBCFLH_00108 0.0 clpC O Belongs to the ClpA ClpB family
KCIBCFLH_00109 5.5e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KCIBCFLH_00110 3.4e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KCIBCFLH_00111 1.1e-119 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KCIBCFLH_00112 1.1e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KCIBCFLH_00113 7.2e-283 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCIBCFLH_00114 1.1e-108 cysE 2.3.1.30 E Serine acetyltransferase
KCIBCFLH_00115 2.4e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCIBCFLH_00116 4.4e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KCIBCFLH_00117 4.8e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCIBCFLH_00118 8.7e-90 yacP S RNA-binding protein containing a PIN domain
KCIBCFLH_00119 1.1e-113 sigH K Belongs to the sigma-70 factor family
KCIBCFLH_00121 1e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KCIBCFLH_00122 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
KCIBCFLH_00123 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCIBCFLH_00124 9.5e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KCIBCFLH_00126 5.4e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KCIBCFLH_00127 1.3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KCIBCFLH_00128 4.2e-112 rsmC 2.1.1.172 J Methyltransferase
KCIBCFLH_00129 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCIBCFLH_00130 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCIBCFLH_00131 2.6e-36 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
KCIBCFLH_00132 8.6e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KCIBCFLH_00133 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KCIBCFLH_00134 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCIBCFLH_00135 2.7e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCIBCFLH_00136 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KCIBCFLH_00137 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KCIBCFLH_00138 1.1e-104 rplD J Forms part of the polypeptide exit tunnel
KCIBCFLH_00139 5.7e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KCIBCFLH_00140 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCIBCFLH_00141 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KCIBCFLH_00142 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KCIBCFLH_00143 2.3e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KCIBCFLH_00144 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KCIBCFLH_00145 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KCIBCFLH_00146 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCIBCFLH_00147 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KCIBCFLH_00148 1.7e-57 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCIBCFLH_00149 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCIBCFLH_00150 5.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCIBCFLH_00151 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KCIBCFLH_00152 6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KCIBCFLH_00153 6.1e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KCIBCFLH_00154 4.7e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KCIBCFLH_00155 7e-23 rpmD J Ribosomal protein L30
KCIBCFLH_00156 1.2e-71 rplO J binds to the 23S rRNA
KCIBCFLH_00157 1.4e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KCIBCFLH_00158 1.7e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KCIBCFLH_00159 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KCIBCFLH_00160 1.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KCIBCFLH_00161 5.2e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KCIBCFLH_00162 6.9e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCIBCFLH_00163 2.8e-59 rplQ J Ribosomal protein L17
KCIBCFLH_00165 2.7e-157 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCIBCFLH_00166 6.4e-162 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCIBCFLH_00167 6e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCIBCFLH_00168 2.7e-137 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KCIBCFLH_00169 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KCIBCFLH_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KCIBCFLH_00171 3.5e-24 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KCIBCFLH_00172 0.0 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KCIBCFLH_00173 2.7e-188 S type I phosphodiesterase nucleotide pyrophosphatase
KCIBCFLH_00174 1.5e-145 S type I phosphodiesterase nucleotide pyrophosphatase
KCIBCFLH_00176 4.4e-227 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KCIBCFLH_00177 7.2e-112 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
KCIBCFLH_00178 1.9e-275 lysP E amino acid
KCIBCFLH_00179 8.8e-83 ybaK S Protein of unknown function (DUF2521)
KCIBCFLH_00180 6.2e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KCIBCFLH_00181 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KCIBCFLH_00182 4.8e-70 gerD S Spore gernimation protein
KCIBCFLH_00183 3.9e-108 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KCIBCFLH_00184 1.5e-10 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KCIBCFLH_00185 2.3e-181 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
KCIBCFLH_00186 6.5e-173 K Transcriptional regulator
KCIBCFLH_00187 5.5e-138 pdaB 3.5.1.104 G xylanase chitin deacetylase
KCIBCFLH_00188 2.6e-30
KCIBCFLH_00189 7.1e-256 cydA 1.10.3.14 C oxidase, subunit
KCIBCFLH_00190 2.2e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KCIBCFLH_00191 0.0 cydD V ATP-binding
KCIBCFLH_00192 0.0 cydD V ATP-binding protein
KCIBCFLH_00193 4.3e-42 S COG NOG14552 non supervised orthologous group
KCIBCFLH_00194 5.3e-43
KCIBCFLH_00199 1.7e-07
KCIBCFLH_00200 1.5e-07
KCIBCFLH_00204 1.6e-168 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KCIBCFLH_00206 1.9e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KCIBCFLH_00207 1.9e-115 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KCIBCFLH_00208 5.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KCIBCFLH_00209 6e-222 ybbR S protein conserved in bacteria
KCIBCFLH_00210 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCIBCFLH_00211 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KCIBCFLH_00213 1.2e-94 M1-431 S Protein of unknown function (DUF1706)
KCIBCFLH_00214 6.8e-144 3.1.2.21 I Acyl-ACP thioesterase
KCIBCFLH_00215 5.1e-87
KCIBCFLH_00216 4.1e-82 S cellulose binding
KCIBCFLH_00217 4.8e-66 L PFAM Transposase, IS4-like
KCIBCFLH_00218 5.8e-132 L PFAM Transposase, IS4-like
KCIBCFLH_00219 3.3e-217 G Major facilitator Superfamily
KCIBCFLH_00220 1.5e-83 S Pfam:DUF1399
KCIBCFLH_00221 1.3e-199 EGP Major facilitator Superfamily
KCIBCFLH_00222 3.8e-143 K Bacterial regulatory helix-turn-helix protein, lysR family
KCIBCFLH_00223 0.0 L Domain of unknown function (DUF4277)
KCIBCFLH_00224 1.1e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KCIBCFLH_00225 1.6e-260 NT Chemoreceptor zinc-binding domain
KCIBCFLH_00226 8.3e-114 S Putative adhesin
KCIBCFLH_00227 3.9e-96 S Protein of unknown function (DUF1700)
KCIBCFLH_00228 1.3e-54 K PadR family transcriptional regulator
KCIBCFLH_00229 9.5e-181 NT chemotaxis protein
KCIBCFLH_00230 7.4e-253 EGP Major facilitator superfamily
KCIBCFLH_00231 1.3e-102 Q Isochorismatase family
KCIBCFLH_00232 1.1e-107 K Transcriptional regulator
KCIBCFLH_00233 6.4e-60
KCIBCFLH_00234 4.6e-127
KCIBCFLH_00235 5.2e-44 ltaA 4.1.2.48 E L-allo-threonine aldolase activity
KCIBCFLH_00236 1.4e-212 EGP Major Facilitator Superfamily
KCIBCFLH_00237 1.4e-133 F ATP-grasp domain
KCIBCFLH_00238 6.3e-21 F ATP-grasp domain
KCIBCFLH_00239 3.2e-211 K helix_turn_helix, Arsenical Resistance Operon Repressor
KCIBCFLH_00240 1.7e-51 ykvR S Protein of unknown function (DUF3219)
KCIBCFLH_00241 7.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCIBCFLH_00243 1.2e-217 yjbB G Major Facilitator Superfamily
KCIBCFLH_00245 3.4e-97 rimJ 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KCIBCFLH_00247 1e-87 2.3.1.128 J Acetyltransferase (GNAT) domain
KCIBCFLH_00248 2.3e-248 L PFAM Transposase, IS4-like
KCIBCFLH_00249 1.3e-72 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
KCIBCFLH_00251 1.7e-116 E lactoylglutathione lyase activity
KCIBCFLH_00252 4.5e-233 lmrP E Transmembrane secretion effector
KCIBCFLH_00253 1.1e-74 yycN 2.3.1.128, 2.3.1.57 K FR47-like protein
KCIBCFLH_00254 2.2e-132 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KCIBCFLH_00255 1.3e-115 V CAAX protease self-immunity
KCIBCFLH_00256 2.9e-11
KCIBCFLH_00257 3.1e-237 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 I Hydroxymethylglutaryl-coenzyme A reductase
KCIBCFLH_00258 3.3e-222 mvaS 2.3.3.10 I synthase
KCIBCFLH_00259 1.1e-55 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_00260 1.4e-198 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_00261 7.4e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
KCIBCFLH_00262 2.9e-54 S DsrE/DsrF-like family
KCIBCFLH_00263 1.1e-77
KCIBCFLH_00264 3.5e-185 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCIBCFLH_00266 3.5e-177 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KCIBCFLH_00267 5.8e-275 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
KCIBCFLH_00268 2.8e-82 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KCIBCFLH_00269 2.9e-265 treP 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KCIBCFLH_00270 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCIBCFLH_00271 2.2e-131 treR K transcriptional
KCIBCFLH_00272 1.3e-230 EG COG2610 H gluconate symporter and related permeases
KCIBCFLH_00274 1.1e-308 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KCIBCFLH_00275 2.2e-125 gntR K transcriptional
KCIBCFLH_00276 6e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KCIBCFLH_00277 6.5e-81 fld C Flavodoxin
KCIBCFLH_00278 4.3e-200 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KCIBCFLH_00279 1.6e-153 T PhoQ Sensor
KCIBCFLH_00280 1.5e-100 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCIBCFLH_00281 1.5e-76 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KCIBCFLH_00282 4.4e-108 natA V COG1131 ABC-type multidrug transport system, ATPase component
KCIBCFLH_00284 3.3e-113 4.1.99.16, 4.2.3.22, 4.2.3.75 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KCIBCFLH_00285 0.0 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KCIBCFLH_00286 2.8e-29 P Heavy-metal-associated domain
KCIBCFLH_00287 1.7e-178 tnp4 L Transposase, Mutator family
KCIBCFLH_00290 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCIBCFLH_00291 1.6e-87 fld C Flavodoxin
KCIBCFLH_00292 5.2e-195 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCIBCFLH_00293 8.9e-110 plsY 2.3.1.15 I Belongs to the PlsY family
KCIBCFLH_00294 7.3e-208 crtQ M Glycosyl transferase family 21
KCIBCFLH_00295 4.6e-150 S transposase or invertase
KCIBCFLH_00296 6.9e-18 S transposase or invertase
KCIBCFLH_00297 3.2e-16 S transposase or invertase
KCIBCFLH_00298 6.1e-93 Q Thioesterase superfamily
KCIBCFLH_00299 2.8e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KCIBCFLH_00300 1e-48 sugE P Multidrug resistance protein
KCIBCFLH_00301 6.6e-54 ykkC P Multidrug resistance protein
KCIBCFLH_00302 2e-138 yfcA S membrane transporter protein
KCIBCFLH_00303 1.5e-181 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCIBCFLH_00304 7.4e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCIBCFLH_00305 2.6e-172 fhuD P Periplasmic binding protein
KCIBCFLH_00306 1.6e-151 fhuC 3.6.3.34 HP ABC transporter
KCIBCFLH_00307 7e-200 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KCIBCFLH_00308 1.6e-114
KCIBCFLH_00309 5.9e-106
KCIBCFLH_00310 2e-106
KCIBCFLH_00311 3.8e-128 yeeN K transcriptional regulatory protein
KCIBCFLH_00312 1.3e-190 T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
KCIBCFLH_00313 3.1e-242 MA20_26760 1.3.8.7 I COG1960 Acyl-CoA dehydrogenases
KCIBCFLH_00314 2.4e-136 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCIBCFLH_00315 1.6e-173 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KCIBCFLH_00316 1.5e-74 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KCIBCFLH_00317 6.7e-96 K Transcriptional regulator
KCIBCFLH_00319 5.6e-68 S Thioesterase-like superfamily
KCIBCFLH_00320 3.9e-198 S Phosphotransferase enzyme family
KCIBCFLH_00321 1.6e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KCIBCFLH_00322 1.1e-198 L COG3039 Transposase and inactivated derivatives, IS5 family
KCIBCFLH_00323 1.1e-269 yobO M Pectate lyase superfamily protein
KCIBCFLH_00324 1.9e-07
KCIBCFLH_00325 2.2e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KCIBCFLH_00326 6e-140 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KCIBCFLH_00327 7.6e-132 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KCIBCFLH_00328 7.7e-109 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KCIBCFLH_00329 7e-95 ywhH S Aminoacyl-tRNA editing domain
KCIBCFLH_00330 1.1e-203 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KCIBCFLH_00331 0.0 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KCIBCFLH_00332 5.1e-190 2.7.7.65 T Diguanylate cyclase, GGDEF domain
KCIBCFLH_00334 1.3e-165 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KCIBCFLH_00335 2.6e-158 S Nuclease-related domain
KCIBCFLH_00336 8.4e-45
KCIBCFLH_00337 9.8e-30
KCIBCFLH_00338 1.9e-164 czcD P COG1230 Co Zn Cd efflux system component
KCIBCFLH_00339 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KCIBCFLH_00340 2.2e-114 M Glycosyltransferase like family 2
KCIBCFLH_00341 8.8e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases C terminal
KCIBCFLH_00342 9.1e-173 mvaD 4.1.1.33 I GHMP kinases N terminal domain
KCIBCFLH_00343 3e-114 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases C terminal
KCIBCFLH_00344 2.9e-111 yhfK GM NmrA-like family
KCIBCFLH_00345 9e-267 L Transposase
KCIBCFLH_00346 8.5e-190 L ISXO2-like transposase domain
KCIBCFLH_00347 7.5e-103 yyaP 1.5.1.3 H RibD C-terminal domain
KCIBCFLH_00348 8.8e-248 L PFAM Transposase, IS4-like
KCIBCFLH_00349 5.8e-30 S protein conserved in bacteria
KCIBCFLH_00350 2.4e-240 L Transposase DDE domain group 1
KCIBCFLH_00351 2.8e-226 mtlF 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
KCIBCFLH_00352 1.7e-168 mtlR K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KCIBCFLH_00353 2.1e-136 mtlD 1.1.1.17 G Mannitol dehydrogenase Rossmann domain
KCIBCFLH_00354 1.9e-233 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KCIBCFLH_00355 1.1e-110 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCIBCFLH_00356 2.3e-38 gcvR T Belongs to the UPF0237 family
KCIBCFLH_00357 4.5e-247 XK27_08635 S UPF0210 protein
KCIBCFLH_00358 2.5e-269 L RNA-directed DNA polymerase (reverse transcriptase)
KCIBCFLH_00359 1.7e-190 ptxS K transcriptional
KCIBCFLH_00360 9.8e-135 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
KCIBCFLH_00361 2.5e-175 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KCIBCFLH_00362 7.4e-239 G Major Facilitator Superfamily
KCIBCFLH_00363 1.2e-93 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
KCIBCFLH_00364 1.4e-93 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
KCIBCFLH_00367 6.8e-84 cotF M Spore coat protein
KCIBCFLH_00368 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_00369 9.2e-175 iolS C Aldo keto reductase
KCIBCFLH_00370 2.5e-98 ydjA C Nitroreductase family
KCIBCFLH_00371 6.5e-254 E COG1113 Gamma-aminobutyrate permease and related permeases
KCIBCFLH_00372 8.5e-17
KCIBCFLH_00373 2.1e-274 dtpT E amino acid peptide transporter
KCIBCFLH_00374 4.9e-279 lysP E amino acid
KCIBCFLH_00376 2.3e-99 puuR K Cupin domain
KCIBCFLH_00377 2.5e-211 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KCIBCFLH_00378 9.6e-141 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
KCIBCFLH_00379 9.2e-139 potC E COG1177 ABC-type spermidine putrescine transport system, permease component II
KCIBCFLH_00380 2.2e-204 potD E COG0687 Spermidine putrescine-binding periplasmic protein
KCIBCFLH_00381 6.9e-267 H HemY protein
KCIBCFLH_00382 1.7e-178 tnp4 L Transposase, Mutator family
KCIBCFLH_00383 8.2e-252 E amino acid
KCIBCFLH_00384 2.7e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KCIBCFLH_00385 1.1e-272 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KCIBCFLH_00386 7.7e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KCIBCFLH_00387 3.6e-221 pucR QT Transcriptional regulator
KCIBCFLH_00388 1.7e-265 2.6.1.55 H Aminotransferase class-III
KCIBCFLH_00389 3.6e-213 C alcohol dehydrogenase
KCIBCFLH_00390 1.1e-231 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KCIBCFLH_00391 1.6e-293 FH COG1953 Cytosine uracil thiamine allantoin permeases
KCIBCFLH_00392 1.5e-255 gltD 1.3.1.1 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KCIBCFLH_00393 1.1e-231 preA 1.3.1.1 CF dihydroorotate dehydrogenase
KCIBCFLH_00394 3.8e-273 hyuA 3.5.2.2 F Amidohydrolase family
KCIBCFLH_00396 5.7e-253 E Amino acid permease
KCIBCFLH_00398 6e-224 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KCIBCFLH_00399 3.4e-233 amt P Ammonium transporter
KCIBCFLH_00400 5.4e-292 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KCIBCFLH_00401 1.6e-120 citT T response regulator
KCIBCFLH_00402 5e-238 citH C Citrate transporter
KCIBCFLH_00403 6.6e-96 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KCIBCFLH_00404 1.8e-75 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KCIBCFLH_00405 0.0 helD 3.6.4.12 L DNA helicase
KCIBCFLH_00407 3.9e-33
KCIBCFLH_00408 4.2e-17
KCIBCFLH_00410 2.5e-30 K Cro/C1-type HTH DNA-binding domain
KCIBCFLH_00411 2.2e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KCIBCFLH_00412 1.4e-147 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KCIBCFLH_00413 1.2e-290 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KCIBCFLH_00414 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KCIBCFLH_00415 1.8e-213 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KCIBCFLH_00416 6.6e-122 K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KCIBCFLH_00417 7.3e-199 L COG3039 Transposase and inactivated derivatives, IS5 family
KCIBCFLH_00418 3.6e-131 ric D Di-iron-containing protein involved in the repair of iron-sulfur clusters
KCIBCFLH_00419 6.4e-96 S Belongs to the UPF0312 family
KCIBCFLH_00420 7.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KCIBCFLH_00422 2.6e-191 T HD domain
KCIBCFLH_00423 2e-275 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
KCIBCFLH_00425 0.0 ydaO E amino acid
KCIBCFLH_00426 1.6e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KCIBCFLH_00427 3e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KCIBCFLH_00428 1.2e-172 ydbI S AI-2E family transporter
KCIBCFLH_00429 1.5e-132 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KCIBCFLH_00431 1.3e-135 glnH ET Belongs to the bacterial solute-binding protein 3 family
KCIBCFLH_00432 1.2e-109 gluC P ABC transporter
KCIBCFLH_00433 2.3e-117 glnP P ABC transporter
KCIBCFLH_00434 3.8e-69 K helix_turn_helix gluconate operon transcriptional repressor
KCIBCFLH_00435 7.6e-197 S Protein of unknown function (DUF1648)
KCIBCFLH_00436 3.3e-55 yodB K transcriptional
KCIBCFLH_00438 3.1e-234 S SNARE associated Golgi protein
KCIBCFLH_00439 2.6e-98 yngC S membrane-associated protein
KCIBCFLH_00440 9.5e-159 msrR K COG1316 Transcriptional regulator
KCIBCFLH_00441 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KCIBCFLH_00442 0.0 metH 2.1.1.13 E Methionine synthase
KCIBCFLH_00443 3.4e-12 csbD S Belongs to the UPF0337 (CsbD) family
KCIBCFLH_00444 1.4e-86 K ComK protein
KCIBCFLH_00445 6.4e-105 sigS 2.7.7.6 K Belongs to the sigma-70 factor family. ECF subfamily
KCIBCFLH_00446 1.7e-148 E lipolytic protein G-D-S-L family
KCIBCFLH_00447 9e-117 ywqC M biosynthesis protein
KCIBCFLH_00448 7.2e-108 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KCIBCFLH_00449 1.9e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KCIBCFLH_00450 3.2e-156 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KCIBCFLH_00451 3.7e-88 cpsE M Bacterial sugar transferase
KCIBCFLH_00452 3e-43 GT2 V Glycosyl transferase, family 2
KCIBCFLH_00453 1.2e-89 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KCIBCFLH_00454 2.2e-152 rgpAc GT4 M Domain of unknown function (DUF1972)
KCIBCFLH_00455 2e-125 S polysaccharide biosynthetic process
KCIBCFLH_00456 7.4e-104 G Glycosyl transferases group 1
KCIBCFLH_00457 3.2e-61
KCIBCFLH_00458 6.9e-148 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCIBCFLH_00459 1.3e-17 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KCIBCFLH_00460 2.6e-56 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KCIBCFLH_00461 8e-133 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KCIBCFLH_00462 3.5e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KCIBCFLH_00463 1.2e-142 D nuclear chromosome segregation
KCIBCFLH_00464 6.4e-117 xylR GK Transcriptional regulator
KCIBCFLH_00465 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
KCIBCFLH_00466 8.9e-198 xylP G COGs COG2211 Na melibiose symporter and related transporter
KCIBCFLH_00467 1.7e-259 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KCIBCFLH_00468 1.9e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
KCIBCFLH_00469 0.0 M Non-essential cell division protein that could be required for efficient cell constriction
KCIBCFLH_00470 3.2e-59 croE S Helix-turn-helix
KCIBCFLH_00471 3.5e-135 E IrrE N-terminal-like domain
KCIBCFLH_00472 1.9e-38
KCIBCFLH_00473 3.4e-247 yicJ G MFS/sugar transport protein
KCIBCFLH_00474 2.9e-303 2.7.1.12, 2.7.1.17 G xylulose kinase
KCIBCFLH_00475 1.1e-15 S Ribbon-helix-helix protein, copG family
KCIBCFLH_00476 2.5e-211 L Transposase
KCIBCFLH_00477 7.8e-83 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCIBCFLH_00478 1e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KCIBCFLH_00479 5.3e-110 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KCIBCFLH_00480 1.8e-55 L Transposase IS200 like
KCIBCFLH_00481 5.5e-99 L Transposase
KCIBCFLH_00482 6.5e-284 L Transposase
KCIBCFLH_00483 2.4e-80 rhaR K helix_turn_helix, arabinose operon control protein
KCIBCFLH_00484 1.1e-167 iolF EGP Major facilitator Superfamily
KCIBCFLH_00485 4.2e-130 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KCIBCFLH_00486 2.1e-41 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KCIBCFLH_00487 1.3e-43 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KCIBCFLH_00488 9.8e-204 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
KCIBCFLH_00489 7.2e-107 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
KCIBCFLH_00490 4.2e-161 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
KCIBCFLH_00491 0.0 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KCIBCFLH_00492 9e-197 yngA M GtrA-like protein
KCIBCFLH_00493 3.5e-124 ykoT GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KCIBCFLH_00495 8e-28 yodI
KCIBCFLH_00496 2.8e-148 yjaZ O Zn-dependent protease
KCIBCFLH_00497 3.4e-129 yodH Q Methyltransferase
KCIBCFLH_00499 8.3e-141 S PD-(D/E)XK nuclease family transposase
KCIBCFLH_00500 0.0 gtfC 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KCIBCFLH_00501 8.1e-162 S HipA-like C-terminal domain
KCIBCFLH_00502 1.6e-145 S HIRAN domain
KCIBCFLH_00503 2.8e-111 IQ Enoyl-(Acyl carrier protein) reductase
KCIBCFLH_00504 5.8e-192 srlR2 2.7.1.202 K transcriptional regulator, MtlR
KCIBCFLH_00505 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_00506 1e-44 gutM K Glucitol operon activator protein (GutM)
KCIBCFLH_00507 5.9e-81 srlA G PTS system enzyme II sorbitol-specific factor
KCIBCFLH_00508 1.8e-155 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
KCIBCFLH_00509 6.4e-39 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KCIBCFLH_00510 2.3e-77 tal 2.2.1.2 H COG0176 Transaldolase
KCIBCFLH_00511 5.2e-29 K Cro/C1-type HTH DNA-binding domain
KCIBCFLH_00512 5e-102 K Periplasmic binding protein domain
KCIBCFLH_00513 6e-52 fucU 5.1.3.29 G Belongs to the RbsD FucU family
KCIBCFLH_00514 5.8e-227 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KCIBCFLH_00515 2e-127 rbsC G Belongs to the binding-protein-dependent transport system permease family
KCIBCFLH_00516 2.3e-123 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KCIBCFLH_00517 1e-208 rhaB 2.7.1.189, 2.7.1.5 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KCIBCFLH_00518 0.0 fucI 5.3.1.25, 5.3.1.3 G Converts the aldose L-fucose into the corresponding ketose L-fuculose
KCIBCFLH_00519 4.7e-101 fucA 2.7.1.189, 4.1.2.17, 4.1.2.19, 5.1.3.4 G Aldolase
KCIBCFLH_00520 9e-186 araB G FGGY family of carbohydrate kinases, C-terminal domain
KCIBCFLH_00521 2.1e-42 araB G FGGY family of carbohydrate kinases, C-terminal domain
KCIBCFLH_00522 4.1e-79 S Uncharacterised protein family UPF0047
KCIBCFLH_00523 9.2e-98 tpiA 5.3.1.1 G triosephosphate isomerase
KCIBCFLH_00524 5e-79 4.1.2.13 G aldolase
KCIBCFLH_00525 2.5e-30 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
KCIBCFLH_00526 8.9e-153 G PTS system sugar-specific permease component
KCIBCFLH_00527 8.5e-33 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KCIBCFLH_00528 3.2e-16 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KCIBCFLH_00529 6.7e-119 manR K PRD domain
KCIBCFLH_00530 1.3e-30
KCIBCFLH_00531 9e-290 K COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KCIBCFLH_00532 1.5e-189 S Protein of unknown function (DUF917)
KCIBCFLH_00533 1e-279 apc3 3.5.2.9 EQ Hydantoinase oxoprolinase
KCIBCFLH_00534 1.9e-205 codB F cytosine purines uracil thiamine allantoin
KCIBCFLH_00535 5e-204 S Protein of unknown function (DUF917)
KCIBCFLH_00536 3.1e-284 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
KCIBCFLH_00537 1.4e-178 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KCIBCFLH_00538 5.4e-67 yjbR S YjbR
KCIBCFLH_00539 2e-29 S Protein of unknown function (DUF1648)
KCIBCFLH_00540 7.8e-244 L Metallo-beta-lactamase superfamily
KCIBCFLH_00541 2.8e-26 S Protein of unknown function (DUF3006)
KCIBCFLH_00543 9.9e-27 L Metal dependent phosphohydrolases with conserved 'HD' motif.
KCIBCFLH_00544 2.1e-243 L Metal dependent phosphohydrolases with conserved 'HD' motif.
KCIBCFLH_00545 2.7e-42 L Metal dependent phosphohydrolases with conserved 'HD' motif.
KCIBCFLH_00546 1e-116 S CRISPR-associated protein
KCIBCFLH_00547 0.0 csd1 S CRISPR-associated protein (Cas_Csd1)
KCIBCFLH_00548 1.5e-156 csd2 L CRISPR-associated protein Cas7
KCIBCFLH_00549 3.6e-27
KCIBCFLH_00550 0.0 ybeC E amino acid
KCIBCFLH_00551 0.0 3.2.1.78 GH26 O cellulase activity
KCIBCFLH_00552 8.6e-176 K cell envelope-related transcriptional attenuator
KCIBCFLH_00553 3.6e-50
KCIBCFLH_00554 5.5e-172 ydhF S Oxidoreductase
KCIBCFLH_00555 1.8e-149 S transposase or invertase
KCIBCFLH_00556 1.4e-20 S transposase or invertase
KCIBCFLH_00558 6.7e-52 S Domain of unknown function (DUF3870)
KCIBCFLH_00559 1.7e-229 B4168_2380 1.3.99.32 I Acyl-CoA dehydrogenase, N-terminal domain
KCIBCFLH_00560 5e-218 C acyl-CoA transferases carnitine dehydratase
KCIBCFLH_00561 3.8e-182 yfmJ S N-terminal domain of oxidoreductase
KCIBCFLH_00562 4.9e-213 EGP Major facilitator Superfamily
KCIBCFLH_00563 0.0 2.7.1.202 K transcriptional regulator, MtlR
KCIBCFLH_00564 9.3e-53 licB 2.7.1.196, 2.7.1.205 G phosphotransferase system
KCIBCFLH_00565 1.2e-52 chbA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KCIBCFLH_00566 8.7e-209 S Bacterial protein of unknown function (DUF871)
KCIBCFLH_00567 2.4e-234 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KCIBCFLH_00568 3.6e-255 gph G MFS/sugar transport protein
KCIBCFLH_00570 2e-237 E Amino acid permease
KCIBCFLH_00571 0.0 K helix_turn_helix, arabinose operon control protein
KCIBCFLH_00572 5.9e-219 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KCIBCFLH_00573 1.7e-179 tdh 4.2.1.45 GM GDP-mannose 4,6 dehydratase
KCIBCFLH_00574 8.6e-193 ydjE EGP Major facilitator superfamily
KCIBCFLH_00575 4.2e-74 K transcriptional
KCIBCFLH_00576 3e-210 EGP Major facilitator Superfamily
KCIBCFLH_00577 5.9e-180 K Transcriptional regulator
KCIBCFLH_00578 0.0 bga2 3.2.1.23 G beta-galactosidase
KCIBCFLH_00580 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KCIBCFLH_00581 1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KCIBCFLH_00582 1.7e-114 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KCIBCFLH_00583 1.8e-209 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KCIBCFLH_00584 1.3e-96 yvbF K Belongs to the GbsR family
KCIBCFLH_00585 1.6e-97 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
KCIBCFLH_00586 1.5e-147 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KCIBCFLH_00587 3.6e-34 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KCIBCFLH_00588 9.3e-46
KCIBCFLH_00589 1.3e-110 yjlB S Cupin domain
KCIBCFLH_00590 3.1e-150 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
KCIBCFLH_00591 1.9e-135 yflN_1 S Metallo-beta-lactamase superfamily
KCIBCFLH_00592 4.8e-295 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KCIBCFLH_00593 3.9e-303 comM O Mg chelatase subunit ChlI
KCIBCFLH_00594 1.1e-149 S transposase or invertase
KCIBCFLH_00595 4.6e-21
KCIBCFLH_00596 7.3e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KCIBCFLH_00597 7.9e-210 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KCIBCFLH_00598 1.4e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KCIBCFLH_00599 8e-304 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KCIBCFLH_00600 1.2e-205 nifS 2.8.1.7 E Cysteine desulfurase
KCIBCFLH_00601 9e-90 S NYN domain
KCIBCFLH_00602 4.6e-143 focA P Formate nitrite
KCIBCFLH_00603 9.7e-220 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KCIBCFLH_00604 6.3e-29 S UPF0397 protein
KCIBCFLH_00605 1.5e-163 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KCIBCFLH_00606 5.2e-123 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KCIBCFLH_00607 8.9e-254 EG COG2610 H gluconate symporter and related permeases
KCIBCFLH_00608 2.6e-277 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KCIBCFLH_00609 5.1e-218 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
KCIBCFLH_00610 4.6e-311 KT Transcriptional regulator
KCIBCFLH_00611 0.0 xylS 3.2.1.20 GH31 G Domain of unknown function (DUF5110)
KCIBCFLH_00612 1.5e-15 xylS 3.2.1.20 GH31 G Domain of unknown function (DUF5110)
KCIBCFLH_00613 7.2e-282 Otg1 S Predicted membrane protein (DUF2339)
KCIBCFLH_00614 2e-227 1.3.8.7 I Acyl-CoA dehydrogenase, N-terminal domain
KCIBCFLH_00615 5.7e-286 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KCIBCFLH_00616 1e-195 S Metallo-beta-lactamase superfamily
KCIBCFLH_00617 6.8e-107 K Bacterial regulatory proteins, tetR family
KCIBCFLH_00618 0.0 fldZ 1.3.1.31 C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KCIBCFLH_00619 1.6e-10 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_00620 2.1e-207 ysdC G COG1363 Cellulase M and related proteins
KCIBCFLH_00622 6.8e-44
KCIBCFLH_00623 6.2e-52 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KCIBCFLH_00624 1.6e-108
KCIBCFLH_00625 4.2e-43
KCIBCFLH_00627 3.9e-45 S double-stranded DNA endodeoxyribonuclease activity
KCIBCFLH_00628 1.5e-132 VVA0018 T Histidine kinase
KCIBCFLH_00629 2e-129 T helix_turn_helix, arabinose operon control protein
KCIBCFLH_00630 9.7e-08 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCIBCFLH_00631 1.7e-170 3.5.1.4 C Acetamidase
KCIBCFLH_00632 2.9e-225 puuP_1 E Amino acid permease
KCIBCFLH_00633 2.3e-21 S Zinc-ribbon containing domain
KCIBCFLH_00634 1.4e-298 yvfH C L-lactate permease
KCIBCFLH_00635 1.1e-122 yvfI K COG2186 Transcriptional regulators
KCIBCFLH_00636 5.1e-231 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KCIBCFLH_00637 3.9e-60
KCIBCFLH_00639 1.3e-168 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KCIBCFLH_00640 1.6e-219 EGP Major facilitator Superfamily
KCIBCFLH_00641 4.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KCIBCFLH_00642 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_00643 2.2e-16 S YvrJ protein family
KCIBCFLH_00644 9.8e-11 S Protein of unknown function (DUF2922)
KCIBCFLH_00645 5.8e-11 S Protein of unknown function (DUF1659)
KCIBCFLH_00646 0.0 O Belongs to the peptidase S8 family
KCIBCFLH_00647 3.3e-68 S Protein of unknown function (DUF2512)
KCIBCFLH_00648 2.9e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KCIBCFLH_00649 4.1e-53 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
KCIBCFLH_00650 1.9e-81
KCIBCFLH_00651 4.1e-248 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KCIBCFLH_00652 9.8e-293 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCIBCFLH_00653 0.0 2.7.1.202 K transcriptional regulator, MtlR
KCIBCFLH_00654 1e-156 kdsA 2.5.1.55 M Belongs to the KdsA family
KCIBCFLH_00655 1.8e-176 kdsD 5.3.1.13 M Belongs to the SIS family. GutQ KpsF subfamily
KCIBCFLH_00656 6.4e-92 L PFAM Transposase, IS4-like
KCIBCFLH_00657 4.3e-22 L PFAM Transposase, IS4-like
KCIBCFLH_00658 2.6e-55 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_00659 7.6e-197 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_00661 6.3e-229 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KCIBCFLH_00662 1.2e-216 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KCIBCFLH_00663 0.0 treP 2.4.1.64 GH65 G Glycoside hydrolase, family 65
KCIBCFLH_00664 1.1e-147 G Binding-protein-dependent transport system inner membrane component
KCIBCFLH_00665 1.7e-221 sugA G Binding-protein-dependent transport system inner membrane component
KCIBCFLH_00666 4.7e-227 G Bacterial extracellular solute-binding protein
KCIBCFLH_00667 1.3e-131 K helix_turn_helix, arabinose operon control protein
KCIBCFLH_00668 2.8e-139 gumM 2.4.1.187, 2.4.1.252 GT26,GT4 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KCIBCFLH_00669 3.4e-52 S Iron-sulphur cluster biosynthesis
KCIBCFLH_00670 2.2e-179 yhfP 1.1.1.1 C Quinone oxidoreductase
KCIBCFLH_00671 1.7e-159 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCIBCFLH_00672 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KCIBCFLH_00673 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
KCIBCFLH_00674 1e-87
KCIBCFLH_00675 4.1e-147 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KCIBCFLH_00676 1.8e-133 IQ Short-chain dehydrogenase reductase sdr
KCIBCFLH_00677 5.5e-30 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KCIBCFLH_00678 5.2e-110 cyoC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KCIBCFLH_00679 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCIBCFLH_00680 1.7e-160 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KCIBCFLH_00681 4.4e-123 yhcW 5.4.2.6 S hydrolase
KCIBCFLH_00682 2.6e-166 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KCIBCFLH_00683 1.1e-130 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCIBCFLH_00684 2e-129 macB V ABC transporter, ATP-binding protein
KCIBCFLH_00685 7.3e-153 V COG0577 ABC-type antimicrobial peptide transport system, permease component
KCIBCFLH_00686 2.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCIBCFLH_00687 3.8e-232 T PhoQ Sensor
KCIBCFLH_00688 1.3e-21
KCIBCFLH_00689 0.0 ppc 4.1.1.31 C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KCIBCFLH_00691 1.2e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KCIBCFLH_00692 8.3e-75 yabE S 3D domain
KCIBCFLH_00693 1e-96 relA_2 2.7.6.5, 3.1.7.2 KT HD domain
KCIBCFLH_00694 0.0 pip S YhgE Pip N-terminal domain protein
KCIBCFLH_00695 1.4e-47 yqgV S Thiamine-binding protein
KCIBCFLH_00696 1.3e-196 pgl 3.1.1.31 G 6-phosphogluconolactonase
KCIBCFLH_00697 0.0 S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KCIBCFLH_00698 0.0 levR K PTS system fructose IIA component
KCIBCFLH_00699 2.4e-84 manX 2.7.1.191 G PTS system sorbose subfamily IIB component
KCIBCFLH_00700 2.4e-178 manL 2.7.1.191 G PTS system mannose fructose sorbose family
KCIBCFLH_00701 3.6e-119 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KCIBCFLH_00702 1.9e-169 manN G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KCIBCFLH_00703 9.1e-65 manO S Domain of unknown function (DUF956)
KCIBCFLH_00704 1.1e-211 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KCIBCFLH_00705 5.6e-280 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KCIBCFLH_00706 4.5e-166 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KCIBCFLH_00707 1.2e-80 S Heat induced stress protein YflT
KCIBCFLH_00708 5.6e-275 nylA 3.5.1.4 J Belongs to the amidase family
KCIBCFLH_00709 4.5e-120 M1-594 S Thiamine-binding protein
KCIBCFLH_00710 1.3e-140 ssuC_1 P binding-protein-dependent transport systems inner membrane component
KCIBCFLH_00711 2.3e-187 M1-596 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KCIBCFLH_00712 1.6e-140 P ABC transporter, ATP-binding protein
KCIBCFLH_00713 1.2e-166 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KCIBCFLH_00714 6.3e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KCIBCFLH_00715 8.4e-243 hom 1.1.1.3 E homoserine dehydrogenase
KCIBCFLH_00716 9.8e-146 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KCIBCFLH_00717 1.5e-17 S Protein of unknown function (DUF4064)
KCIBCFLH_00718 4.5e-288 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KCIBCFLH_00719 5.7e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KCIBCFLH_00720 1.5e-45 yhdT S Sodium pantothenate symporter
KCIBCFLH_00721 1.2e-234 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCIBCFLH_00724 1.6e-171 corA P Mg2 transporter protein CorA family protein
KCIBCFLH_00725 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCIBCFLH_00726 1.7e-178 tnp4 L Transposase, Mutator family
KCIBCFLH_00727 1.6e-205 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KCIBCFLH_00728 5.4e-84
KCIBCFLH_00729 1.1e-77 lytE CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KCIBCFLH_00730 2.7e-137 map 3.4.11.18 E Methionine aminopeptidase
KCIBCFLH_00731 1.8e-99 bioY S Biotin biosynthesis protein
KCIBCFLH_00732 4.4e-62 cueR K transcriptional
KCIBCFLH_00733 4.1e-264 6.2.1.3, 6.2.1.34 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KCIBCFLH_00734 0.0 aidB I Acyl-CoA dehydrogenase, middle domain
KCIBCFLH_00735 4.1e-175 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCIBCFLH_00736 1.1e-155 aacC 2.3.1.81 V aminoglycoside
KCIBCFLH_00737 3e-235 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KCIBCFLH_00738 6.3e-70 yxiE T Belongs to the universal stress protein A family
KCIBCFLH_00739 8.4e-28
KCIBCFLH_00740 3.3e-69
KCIBCFLH_00741 1.4e-228 yfkA S YfkB-like domain
KCIBCFLH_00743 1.6e-285 K NB-ARC domain
KCIBCFLH_00744 1.1e-200 gutB 1.1.1.14 E Dehydrogenase
KCIBCFLH_00745 2.1e-88 gutA G MFS/sugar transport protein
KCIBCFLH_00746 1.1e-87 gutA G MFS/sugar transport protein
KCIBCFLH_00748 1.4e-181 ykvZ 5.1.1.1 K Transcriptional regulator
KCIBCFLH_00749 5.1e-93 hxlB 4.1.2.43, 5.3.1.27 M arabinose-5-phosphate isomerase activity
KCIBCFLH_00750 1.4e-147 ykrA S hydrolases of the HAD superfamily
KCIBCFLH_00752 1e-147 yvaK 3.1.1.1 S BAAT / Acyl-CoA thioester hydrolase C terminal
KCIBCFLH_00753 0.0 ubiE2 Q Methyltransferase domain
KCIBCFLH_00754 7.2e-183 tas 1.1.1.65 C Aldo/keto reductase family
KCIBCFLH_00755 1.8e-113 M Spore coat protein
KCIBCFLH_00756 2.1e-137 I alpha/beta hydrolase fold
KCIBCFLH_00757 2.1e-154 S Aldo/keto reductase family
KCIBCFLH_00758 3.6e-97 1.5.1.38 S FMN reductase
KCIBCFLH_00760 2.9e-114 K Helix-turn-helix XRE-family like proteins
KCIBCFLH_00761 5.5e-247 yhaO L Calcineurin-like phosphoesterase superfamily domain
KCIBCFLH_00762 0.0 L AAA domain
KCIBCFLH_00763 6.5e-154 mmgB 1.1.1.157 I Dehydrogenase
KCIBCFLH_00764 6.7e-246 yeeO V Mate efflux family protein
KCIBCFLH_00766 5e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KCIBCFLH_00767 5.3e-58 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KCIBCFLH_00768 1.6e-111 yhbD K Protein of unknown function (DUF4004)
KCIBCFLH_00769 7.2e-225 yhdR 2.6.1.1 E Aminotransferase
KCIBCFLH_00770 2.7e-98 proA_2 H Methyltransferase
KCIBCFLH_00771 0.0 rafA 3.2.1.22 G Alpha-galactosidase
KCIBCFLH_00772 3.2e-50 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCIBCFLH_00773 2.6e-266 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCIBCFLH_00774 3.4e-146 ubiE Q Methyltransferase type 11
KCIBCFLH_00775 7.8e-39
KCIBCFLH_00776 7.7e-163 S Acetyl xylan esterase (AXE1)
KCIBCFLH_00777 3.9e-153 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KCIBCFLH_00778 1.7e-85 thiW S Thiamine-precursor transporter protein (ThiW)
KCIBCFLH_00780 1e-270 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KCIBCFLH_00781 5.3e-254 pucI FH Permease for cytosine/purines, uracil, thiamine, allantoin
KCIBCFLH_00782 2.1e-79 yjhE S Phage tail protein
KCIBCFLH_00784 3.5e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCIBCFLH_00785 8.1e-252 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KCIBCFLH_00786 1e-271 EGP Major facilitator Superfamily
KCIBCFLH_00787 4e-113 K Bacterial regulatory proteins, tetR family
KCIBCFLH_00788 1.4e-260 L Transposase, IS4 family protein
KCIBCFLH_00789 1.3e-85 K Winged helix DNA-binding domain
KCIBCFLH_00790 0.0 ydgH S drug exporters of the RND superfamily
KCIBCFLH_00791 7.3e-149 hel M 5'-nucleotidase, lipoprotein e(P4)
KCIBCFLH_00794 7.2e-214 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KCIBCFLH_00795 2.5e-17 I acyl-CoA dehydrogenase activity
KCIBCFLH_00796 1.8e-12
KCIBCFLH_00797 3.2e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KCIBCFLH_00798 1.7e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCIBCFLH_00799 8.6e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KCIBCFLH_00800 1.7e-201 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
KCIBCFLH_00801 5.7e-183 K Transcriptional regulator
KCIBCFLH_00802 5.1e-32 S Cold-inducible protein YdjO
KCIBCFLH_00803 1.5e-14
KCIBCFLH_00805 2.3e-164 cvfB S protein conserved in bacteria
KCIBCFLH_00806 4e-71 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KCIBCFLH_00807 1.8e-96 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCIBCFLH_00808 1.6e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCIBCFLH_00809 1.2e-274 yusP P Major facilitator superfamily
KCIBCFLH_00810 8.3e-210 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCIBCFLH_00811 5.2e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KCIBCFLH_00812 5.6e-124 gntR1 K transcriptional
KCIBCFLH_00813 2.8e-187 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KCIBCFLH_00814 8.8e-228 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KCIBCFLH_00815 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KCIBCFLH_00816 2.7e-167 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KCIBCFLH_00817 1.4e-113 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KCIBCFLH_00818 1.3e-205 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KCIBCFLH_00819 5.4e-124 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KCIBCFLH_00820 2.2e-260 yfnA E amino acid
KCIBCFLH_00821 2.8e-154 degV S protein conserved in bacteria
KCIBCFLH_00823 3.6e-268 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KCIBCFLH_00824 3e-133 comFC S Phosphoribosyl transferase domain
KCIBCFLH_00825 4.4e-70 yvyF S flagellar protein
KCIBCFLH_00826 6.1e-39 flgM KNU Negative regulator of flagellin synthesis
KCIBCFLH_00827 2.6e-77 flgN NOU FlgN protein
KCIBCFLH_00828 2e-286 flgK N flagellar hook-associated protein
KCIBCFLH_00829 4.3e-153 flgL N Belongs to the bacterial flagellin family
KCIBCFLH_00830 4.3e-77 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KCIBCFLH_00831 4.3e-25 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KCIBCFLH_00832 4.2e-83 hag N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KCIBCFLH_00833 2e-138 M Glycosyl transferase family 2
KCIBCFLH_00834 1.7e-250 L Transposase, IS4 family protein
KCIBCFLH_00835 7.8e-09 ycbZ 3.4.21.53 O AAA domain
KCIBCFLH_00836 0.0 ycbZ 3.4.21.53 O AAA domain
KCIBCFLH_00838 2.9e-105 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KCIBCFLH_00840 6e-61 flaG N flagellar protein FlaG
KCIBCFLH_00841 3.7e-224 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KCIBCFLH_00842 3.9e-69 fliS N flagellar protein FliS
KCIBCFLH_00843 1.1e-56 fliT S bacterial-type flagellum organization
KCIBCFLH_00844 2.7e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KCIBCFLH_00845 3.9e-298 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KCIBCFLH_00846 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KCIBCFLH_00847 3.2e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KCIBCFLH_00848 6.1e-157 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KCIBCFLH_00849 2.9e-51 cccB C COG2010 Cytochrome c, mono- and diheme variants
KCIBCFLH_00851 1.4e-136 ftsE D cell division ATP-binding protein FtsE
KCIBCFLH_00852 1.4e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KCIBCFLH_00853 2.6e-93 D peptidase
KCIBCFLH_00854 9.3e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCIBCFLH_00855 1.3e-248 metY 2.5.1.49 E O-acetylhomoserine
KCIBCFLH_00856 3.7e-182 1.1.1.3 E homoserine dehydrogenase
KCIBCFLH_00857 7.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KCIBCFLH_00858 2e-222 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCIBCFLH_00859 3.6e-166 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCIBCFLH_00860 1.8e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCIBCFLH_00861 3.6e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KCIBCFLH_00862 1.1e-178 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KCIBCFLH_00863 2.1e-41 fdxA C 4Fe-4S binding domain
KCIBCFLH_00864 4.5e-46 S Family of unknown function (DUF5316)
KCIBCFLH_00865 1.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCIBCFLH_00866 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KCIBCFLH_00867 8.8e-262 hemY2 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KCIBCFLH_00868 2.5e-161 pstS P Phosphate
KCIBCFLH_00869 7.5e-164 pstC P probably responsible for the translocation of the substrate across the membrane
KCIBCFLH_00870 8.2e-157 pstA P Phosphate transport system permease
KCIBCFLH_00871 7.5e-152 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCIBCFLH_00872 6.4e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCIBCFLH_00874 4.6e-174 M Glycosyltransferase like family 2
KCIBCFLH_00875 0.0
KCIBCFLH_00876 7.8e-58 P EamA-like transporter family
KCIBCFLH_00877 8.6e-51 S EamA-like transporter family
KCIBCFLH_00878 9.3e-118 yfbR S HD containing hydrolase-like enzyme
KCIBCFLH_00879 2.7e-33 csbA S protein conserved in bacteria
KCIBCFLH_00880 1.6e-09 S Uncharacterized conserved protein (DUF2164)
KCIBCFLH_00881 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KCIBCFLH_00882 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KCIBCFLH_00883 2.8e-72 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KCIBCFLH_00884 4.7e-232 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KCIBCFLH_00885 4.7e-232 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KCIBCFLH_00886 2.7e-146 tagG GM Transport permease protein
KCIBCFLH_00887 0.0 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KCIBCFLH_00888 1.6e-173 yvlB S Putative adhesin
KCIBCFLH_00889 2.5e-32 yvlD S Membrane
KCIBCFLH_00890 4.7e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KCIBCFLH_00891 6e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCIBCFLH_00892 3.5e-120 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KCIBCFLH_00893 1.5e-73 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KCIBCFLH_00894 3e-268 S COG0457 FOG TPR repeat
KCIBCFLH_00895 1.2e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KCIBCFLH_00896 3e-86 yvcI 3.6.1.55 F Nudix hydrolase
KCIBCFLH_00897 4e-167 rapZ S Displays ATPase and GTPase activities
KCIBCFLH_00898 1e-179 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KCIBCFLH_00899 4e-173 whiA K May be required for sporulation
KCIBCFLH_00900 4.3e-40 crh G Phosphocarrier protein Chr
KCIBCFLH_00901 2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KCIBCFLH_00903 1.1e-151 S transposase or invertase
KCIBCFLH_00904 1.8e-14 S transposase or invertase
KCIBCFLH_00905 1.2e-263 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KCIBCFLH_00906 3.4e-29 sspB S spore protein
KCIBCFLH_00907 6.9e-206 msmK P Belongs to the ABC transporter superfamily
KCIBCFLH_00908 2.2e-165 lrp QT PucR C-terminal helix-turn-helix domain
KCIBCFLH_00909 5.7e-230 HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
KCIBCFLH_00910 5e-270 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KCIBCFLH_00911 1.3e-154 yheC HJ YheC/D like ATP-grasp
KCIBCFLH_00912 4.6e-252 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KCIBCFLH_00913 4.5e-208 yheB S Belongs to the UPF0754 family
KCIBCFLH_00914 5.1e-54 yheA S Belongs to the UPF0342 family
KCIBCFLH_00915 1.7e-159 yhaX S hydrolases of the HAD superfamily
KCIBCFLH_00916 1.2e-138 yhaR 5.3.3.18 I enoyl-CoA hydratase
KCIBCFLH_00917 2.9e-27 S YhzD-like protein
KCIBCFLH_00918 6.2e-124 P Integral membrane protein TerC family
KCIBCFLH_00920 4.9e-160 ycgR S permeases
KCIBCFLH_00921 3.3e-163 ycgQ S membrane
KCIBCFLH_00922 1.7e-237 yhaO L DNA repair exonuclease
KCIBCFLH_00923 0.0 L AAA domain
KCIBCFLH_00924 3.7e-179 yhaM L Shows a 3'-5' exoribonuclease activity
KCIBCFLH_00925 3e-27 yhaL S Sporulation protein YhaL
KCIBCFLH_00926 1.9e-153 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KCIBCFLH_00927 1.1e-53 yhaI S Protein of unknown function (DUF1878)
KCIBCFLH_00928 1.5e-103 hpr K Negative regulator of protease production and sporulation
KCIBCFLH_00929 1.2e-18 yhaH S YtxH-like protein
KCIBCFLH_00930 1.1e-84 trpP S Tryptophan transporter TrpP
KCIBCFLH_00931 1.4e-74 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KCIBCFLH_00932 1.9e-138 ecsA V transporter (ATP-binding protein)
KCIBCFLH_00933 2e-222 ecsB U ABC transporter
KCIBCFLH_00934 3.6e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KCIBCFLH_00935 4.5e-234 yhfA C membrane
KCIBCFLH_00936 8.8e-95 traP 1.14.99.57 S enzyme involved in biosynthesis of extracellular polysaccharides
KCIBCFLH_00937 6.2e-199 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KCIBCFLH_00938 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_00939 8.5e-184 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KCIBCFLH_00940 3.2e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KCIBCFLH_00941 5.4e-101 yhgD K Transcriptional regulator
KCIBCFLH_00942 2.8e-192 yhgE S YhgE Pip N-terminal domain protein
KCIBCFLH_00943 8.3e-179 arbF1 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
KCIBCFLH_00944 3.6e-143 ydjF K DeoR C terminal sensor domain
KCIBCFLH_00945 5.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KCIBCFLH_00946 1.5e-242 iolF EGP Major facilitator Superfamily
KCIBCFLH_00947 6.2e-166 EG EamA-like transporter family
KCIBCFLH_00948 3.7e-271 aldA 1.2.1.21, 1.2.1.22 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KCIBCFLH_00949 1.1e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KCIBCFLH_00950 3.6e-64 ytkA S YtkA-like
KCIBCFLH_00951 3e-21 yhfH S YhfH-like protein
KCIBCFLH_00952 3.2e-186 lplJ 6.3.1.20 H Lipoate-protein ligase
KCIBCFLH_00953 3.2e-297 fadD 6.2.1.3 IQ Activates fatty acids by binding to coenzyme A
KCIBCFLH_00955 2e-121 azlC E AzlC protein
KCIBCFLH_00956 3.9e-42 azlD S branched-chain amino acid
KCIBCFLH_00957 1.9e-220 yhfN 3.4.24.84 O Peptidase M48
KCIBCFLH_00958 3.4e-09 S IDEAL
KCIBCFLH_00959 1.6e-99 comK K Competence transcription factor
KCIBCFLH_00960 1.7e-145 S Mitochondrial biogenesis AIM24
KCIBCFLH_00962 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KCIBCFLH_00963 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KCIBCFLH_00964 6.3e-260 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KCIBCFLH_00965 4.2e-30 gerPF S Spore germination protein gerPA/gerPF
KCIBCFLH_00966 3.6e-73 gerPE S Spore germination protein GerPE
KCIBCFLH_00967 2e-25 gerPD S Spore germination protein
KCIBCFLH_00968 2.7e-101 gerPC S Spore germination protein
KCIBCFLH_00969 8.7e-31 gerPA S Spore germination protein
KCIBCFLH_00970 1.9e-222 P Protein of unknown function (DUF418)
KCIBCFLH_00971 2.4e-164 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KCIBCFLH_00972 5.1e-60 yisL S UPF0344 protein
KCIBCFLH_00973 9.3e-106 yisN S Protein of unknown function (DUF2777)
KCIBCFLH_00974 3.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCIBCFLH_00975 5.9e-160 yitS S protein conserved in bacteria
KCIBCFLH_00976 5.7e-26 S Protein of unknown function (DUF3813)
KCIBCFLH_00977 3.8e-156 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KCIBCFLH_00978 9.5e-52 yitW S metal-sulfur cluster biosynthetic enzyme
KCIBCFLH_00979 1.2e-27 yjzC S YjzC-like protein
KCIBCFLH_00980 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KCIBCFLH_00982 1.4e-144 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
KCIBCFLH_00984 1.9e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCIBCFLH_00985 4.3e-236 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KCIBCFLH_00986 2.9e-153 yjaZ O Zn-dependent protease
KCIBCFLH_00987 6.8e-195 oppD P Belongs to the ABC transporter superfamily
KCIBCFLH_00988 7.5e-177 oppF P Belongs to the ABC transporter superfamily
KCIBCFLH_00989 5.2e-173 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCIBCFLH_00990 5.9e-134 oppC EP binding-protein-dependent transport systems inner membrane component
KCIBCFLH_00991 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
KCIBCFLH_00992 6.2e-125 yjbA S Belongs to the UPF0736 family
KCIBCFLH_00993 4e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KCIBCFLH_00995 4.2e-45 S Domain of unknown function (DUF3899)
KCIBCFLH_00996 2.3e-311 dppE_1 E ABC transporter substrate-binding protein
KCIBCFLH_00997 1.2e-153 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCIBCFLH_00998 3.7e-185 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCIBCFLH_00999 6.1e-199 oppD P Belongs to the ABC transporter superfamily
KCIBCFLH_01000 2e-177 oppF E Belongs to the ABC transporter superfamily
KCIBCFLH_01001 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KCIBCFLH_01002 1.2e-120 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KCIBCFLH_01003 2.2e-240 yjbF S Competence protein
KCIBCFLH_01004 0.0 pepF E oligoendopeptidase F
KCIBCFLH_01006 7e-161 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KCIBCFLH_01007 1.4e-74 yjbI S COG2346 Truncated hemoglobins
KCIBCFLH_01009 1.7e-178 tnp4 L Transposase, Mutator family
KCIBCFLH_01011 1.5e-85 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KCIBCFLH_01012 1.1e-106 yjbK S protein conserved in bacteria
KCIBCFLH_01013 1.2e-56 yjbL S Belongs to the UPF0738 family
KCIBCFLH_01014 3.8e-122 yjbM 2.7.6.5 S GTP pyrophosphokinase
KCIBCFLH_01015 4.9e-153 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KCIBCFLH_01016 9.2e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCIBCFLH_01017 2.1e-142 prpE 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KCIBCFLH_01018 4.3e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KCIBCFLH_01021 1.2e-84 cotY S Spore coat protein
KCIBCFLH_01022 8.4e-60 S Protein of unknown function (DUF1360)
KCIBCFLH_01024 6.6e-81 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KCIBCFLH_01025 1.5e-83 spoVAC S stage V sporulation protein AC
KCIBCFLH_01026 3.4e-191 spoVAD I Stage V sporulation protein AD
KCIBCFLH_01027 8.7e-57 spoVAE S stage V sporulation protein
KCIBCFLH_01029 7.1e-199 L COG3039 Transposase and inactivated derivatives, IS5 family
KCIBCFLH_01030 1.7e-178 tnp4 L Transposase, Mutator family
KCIBCFLH_01031 1.1e-198 L COG3039 Transposase and inactivated derivatives, IS5 family
KCIBCFLH_01032 4.5e-39 spoVIF S Stage VI sporulation protein F
KCIBCFLH_01034 3.8e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCIBCFLH_01035 1.5e-94 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KCIBCFLH_01036 1.8e-141 yjcH P COG2382 Enterochelin esterase and related enzymes
KCIBCFLH_01043 7.1e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KCIBCFLH_01044 1.3e-129 IQ Enoyl-(Acyl carrier protein) reductase
KCIBCFLH_01045 8.9e-167 yhaQ S ABC transporter, ATP-binding protein
KCIBCFLH_01046 1.2e-209 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KCIBCFLH_01047 5.4e-261 pepC 3.4.22.40 E Papain family cysteine protease
KCIBCFLH_01048 0.0 pepF2 E COG1164 Oligoendopeptidase F
KCIBCFLH_01049 5.7e-36 ykuS S Belongs to the UPF0180 family
KCIBCFLH_01050 2.1e-25
KCIBCFLH_01051 0.0 6.2.1.1, 6.2.1.16 I AMP-dependent synthetase
KCIBCFLH_01052 4.6e-94 ywrA P COG2059 Chromate transport protein ChrA
KCIBCFLH_01053 1.3e-102 chrA P Chromate transporter
KCIBCFLH_01054 7.2e-83 ywrC K Transcriptional regulator
KCIBCFLH_01055 1.9e-10 EGP Uncharacterised MFS-type transporter YbfB
KCIBCFLH_01056 1e-80 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KCIBCFLH_01057 1.6e-227 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
KCIBCFLH_01058 6.7e-248 L PFAM Transposase, IS4-like
KCIBCFLH_01059 1e-42 EGP Major facilitator Superfamily
KCIBCFLH_01060 1.3e-42 EGP Major facilitator Superfamily
KCIBCFLH_01062 4.3e-158 pocR K Sensory domain found in PocR
KCIBCFLH_01063 1.3e-232 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCIBCFLH_01064 1.2e-213 yxjG 2.1.1.14 E Methionine synthase
KCIBCFLH_01065 1.7e-44 esxA S Belongs to the WXG100 family
KCIBCFLH_01066 1.6e-39 esaA S domain protein
KCIBCFLH_01067 3.5e-37 esaA S domain protein
KCIBCFLH_01068 2.2e-171 esaA S domain protein
KCIBCFLH_01069 1.2e-255 esaA S domain protein
KCIBCFLH_01071 3e-133 S WLM domain
KCIBCFLH_01072 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KCIBCFLH_01073 6.7e-160 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KCIBCFLH_01074 1.5e-291 hsdM 2.1.1.72 V Type I restriction-modification system
KCIBCFLH_01075 6e-95 hsdS2 2.1.1.72 V type I restriction modification DNA specificity domain
KCIBCFLH_01076 2.4e-07 L PFAM Transposase, IS4-like
KCIBCFLH_01077 4.6e-224 L PFAM Transposase, IS4-like
KCIBCFLH_01079 1.2e-185 malR K Transcriptional regulator
KCIBCFLH_01080 4.7e-255 G Major facilitator Superfamily
KCIBCFLH_01081 0.0 mapA 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KCIBCFLH_01082 1.3e-125 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KCIBCFLH_01083 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KCIBCFLH_01084 4.2e-10 S Domain of unknown function (DUF5082)
KCIBCFLH_01085 4.5e-43
KCIBCFLH_01086 1.9e-42 S LXG domain of WXG superfamily
KCIBCFLH_01087 4.5e-180 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KCIBCFLH_01088 1.6e-258 proP EGP Transporter
KCIBCFLH_01089 1.5e-150 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KCIBCFLH_01090 2.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCIBCFLH_01091 1.5e-45
KCIBCFLH_01092 3e-139 tesE Q COG3971 2-keto-4-pentenoate hydratase
KCIBCFLH_01093 4e-146 L Transposase, IS4 family protein
KCIBCFLH_01094 4e-90 L Transposase, IS4 family protein
KCIBCFLH_01095 0.0 L Domain of unknown function (DUF4277)
KCIBCFLH_01096 2.4e-84 tetV EGP Major facilitator Superfamily
KCIBCFLH_01097 3.7e-109 tetV EGP Major facilitator Superfamily
KCIBCFLH_01098 3.3e-74 nsrR K Transcriptional regulator
KCIBCFLH_01099 9.7e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KCIBCFLH_01100 2.3e-48 S membrane transporter protein
KCIBCFLH_01101 6e-60 S membrane transporter protein
KCIBCFLH_01102 8.8e-75 dps P Ferritin-like domain
KCIBCFLH_01103 2.6e-180 mocA S Oxidoreductase
KCIBCFLH_01104 1.6e-207 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KCIBCFLH_01105 1e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KCIBCFLH_01106 3.8e-84
KCIBCFLH_01107 4.7e-143 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KCIBCFLH_01108 1.8e-27 sspD S small acid-soluble spore protein
KCIBCFLH_01109 7.3e-19 S Stage 0 Sporulation Regulatory protein
KCIBCFLH_01111 6.3e-290 kinE 2.7.13.3 T Histidine kinase
KCIBCFLH_01112 4.4e-85 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KCIBCFLH_01113 3.3e-71 XK27_09985 S Protein of unknown function (DUF1232)
KCIBCFLH_01115 0.0 clpE O Belongs to the ClpA ClpB family
KCIBCFLH_01116 4.3e-181 ykvI S membrane
KCIBCFLH_01117 2.7e-106 S Abortive infection protein
KCIBCFLH_01118 2.5e-26 ykvS S protein conserved in bacteria
KCIBCFLH_01119 3.5e-27
KCIBCFLH_01120 3.2e-40 ptsH G phosphocarrier protein HPr
KCIBCFLH_01121 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCIBCFLH_01122 1.4e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCIBCFLH_01123 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KCIBCFLH_01124 6.6e-215 patA 2.6.1.1 E Aminotransferase
KCIBCFLH_01125 1e-162 cheV 2.7.13.3 T Chemotaxis protein CheV
KCIBCFLH_01126 3.1e-86 ykyB S YkyB-like protein
KCIBCFLH_01127 0.0 ydgH S drug exporters of the RND superfamily
KCIBCFLH_01128 0.0 T Diguanylate cyclase
KCIBCFLH_01129 2e-32
KCIBCFLH_01130 3.5e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCIBCFLH_01131 3.9e-170 3.5.1.4 C Acetamidase
KCIBCFLH_01132 5.8e-39 ykuJ S protein conserved in bacteria
KCIBCFLH_01133 6.5e-78 ykuL S CBS domain
KCIBCFLH_01134 4.1e-158 ccpC K Transcriptional regulator
KCIBCFLH_01135 4.7e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KCIBCFLH_01136 1.9e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KCIBCFLH_01137 1.8e-18 S YhfH-like protein
KCIBCFLH_01138 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCIBCFLH_01139 6.8e-30 ykzG S Belongs to the UPF0356 family
KCIBCFLH_01140 9.2e-206 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KCIBCFLH_01141 1.3e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KCIBCFLH_01142 6.8e-232 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KCIBCFLH_01143 9.7e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KCIBCFLH_01144 9.2e-34
KCIBCFLH_01146 2.4e-278 speA 4.1.1.19 E Arginine
KCIBCFLH_01148 7.8e-48 yktA S Belongs to the UPF0223 family
KCIBCFLH_01149 1.4e-118 yktB S Belongs to the UPF0637 family
KCIBCFLH_01150 3.1e-24
KCIBCFLH_01151 5.3e-147 suhB 3.1.3.25 G Inositol monophosphatase
KCIBCFLH_01152 7.8e-25 S Family of unknown function (DUF5325)
KCIBCFLH_01153 0.0 typA T GTP-binding protein TypA
KCIBCFLH_01154 1.2e-52 ylaH S YlaH-like protein
KCIBCFLH_01155 2.8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KCIBCFLH_01156 2.2e-87 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KCIBCFLH_01157 1.5e-43 ylaN S Belongs to the UPF0358 family
KCIBCFLH_01158 3.9e-218 ftsW D Belongs to the SEDS family
KCIBCFLH_01159 1.4e-175 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KCIBCFLH_01160 3.4e-166 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KCIBCFLH_01161 2.4e-203 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KCIBCFLH_01162 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KCIBCFLH_01163 1.2e-114 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KCIBCFLH_01164 1.4e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KCIBCFLH_01165 1.9e-175 ctaG S cytochrome c oxidase
KCIBCFLH_01166 3.7e-63 ylbA S YugN-like family
KCIBCFLH_01167 3.6e-180 ylbC S protein with SCP PR1 domains
KCIBCFLH_01168 4.5e-85 yiiD Q protein, possibly involved in aromatic compounds catabolism
KCIBCFLH_01169 5.8e-70 ylbD S Putative coat protein
KCIBCFLH_01170 1.4e-37 ylbE S YlbE-like protein
KCIBCFLH_01171 2.4e-65
KCIBCFLH_01173 2.5e-15
KCIBCFLH_01174 1.3e-73 ylbF S Belongs to the UPF0342 family
KCIBCFLH_01175 5.3e-46 ylbG S UPF0298 protein
KCIBCFLH_01176 2e-67 S Methylthioribose kinase
KCIBCFLH_01177 1.5e-106 rsmD 2.1.1.171 L Methyltransferase
KCIBCFLH_01178 1.4e-33 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCIBCFLH_01179 1.4e-40 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCIBCFLH_01180 2.3e-218 ylbJ S Sporulation integral membrane protein YlbJ
KCIBCFLH_01181 2.4e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
KCIBCFLH_01182 1.3e-188 ylbL T Belongs to the peptidase S16 family
KCIBCFLH_01183 3.7e-246 ylbM S Belongs to the UPF0348 family
KCIBCFLH_01184 5.3e-97 yceD S metal-binding, possibly nucleic acid-binding protein
KCIBCFLH_01185 1e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KCIBCFLH_01186 7e-84 rsfA S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KCIBCFLH_01187 2.3e-92 ylbP K n-acetyltransferase
KCIBCFLH_01188 1.5e-158 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCIBCFLH_01189 2.2e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KCIBCFLH_01191 7.5e-79 mraZ K Belongs to the MraZ family
KCIBCFLH_01192 4.1e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KCIBCFLH_01193 1.3e-52 ftsL D Essential cell division protein
KCIBCFLH_01194 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KCIBCFLH_01195 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KCIBCFLH_01196 4.3e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KCIBCFLH_01197 5.8e-79 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KCIBCFLH_01198 4.9e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCIBCFLH_01199 2.3e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KCIBCFLH_01200 1.6e-189 spoVE D Belongs to the SEDS family
KCIBCFLH_01201 3.5e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCIBCFLH_01202 2.4e-120 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KCIBCFLH_01203 1.1e-221 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KCIBCFLH_01204 1.2e-189 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCIBCFLH_01205 2.3e-170 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KCIBCFLH_01206 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_01207 7.7e-113 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCIBCFLH_01208 4.9e-137 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCIBCFLH_01209 1.9e-43 ylmC S sporulation protein
KCIBCFLH_01210 2.6e-73 yocH CBM50 M 3D domain
KCIBCFLH_01211 6.9e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KCIBCFLH_01212 3e-119 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCIBCFLH_01213 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KCIBCFLH_01214 2.5e-40 yggT S membrane
KCIBCFLH_01215 1.7e-145 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KCIBCFLH_01216 4.3e-65 divIVA D Cell division initiation protein
KCIBCFLH_01217 3e-108 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KCIBCFLH_01218 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KCIBCFLH_01220 1.6e-266 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_01221 5.4e-81 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KCIBCFLH_01222 2.4e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCIBCFLH_01223 1.5e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KCIBCFLH_01224 3.2e-164 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KCIBCFLH_01225 2e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KCIBCFLH_01226 1e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KCIBCFLH_01227 0.0 carB 6.3.5.5 F Belongs to the CarB family
KCIBCFLH_01228 1.3e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KCIBCFLH_01229 1.6e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KCIBCFLH_01230 4.9e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KCIBCFLH_01231 3.1e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCIBCFLH_01232 2.1e-148 L COG2801 Transposase and inactivated derivatives
KCIBCFLH_01233 7.4e-46 L COG2963 Transposase and inactivated derivatives
KCIBCFLH_01234 3e-170 S Nuclease-related domain
KCIBCFLH_01235 1.2e-205 L Transposase IS4 family protein
KCIBCFLH_01236 5e-167 araC1 K AraC-like ligand binding domain
KCIBCFLH_01237 3.9e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KCIBCFLH_01238 2.5e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
KCIBCFLH_01239 5.2e-161 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
KCIBCFLH_01240 3.6e-31 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C hydroxyacid-oxoacid transhydrogenase activity
KCIBCFLH_01241 1.1e-74 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KCIBCFLH_01242 3.1e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCIBCFLH_01243 6.3e-225 EGP Major facilitator Superfamily
KCIBCFLH_01244 1.8e-265 lmrB EGP the major facilitator superfamily
KCIBCFLH_01245 8.4e-99 yxaF_1 K Transcriptional regulator
KCIBCFLH_01246 2.5e-103 yyaR K Acetyltransferase (GNAT) domain
KCIBCFLH_01247 4e-196 S AI-2E family transporter
KCIBCFLH_01248 7e-161 S hydrolases of the HAD superfamily
KCIBCFLH_01249 0.0 S FAD binding domain
KCIBCFLH_01250 2.4e-264 yihP G MFS/sugar transport protein
KCIBCFLH_01251 4e-53 L Transposase
KCIBCFLH_01252 2.5e-10 L DDE superfamily endonuclease
KCIBCFLH_01253 3.1e-89 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
KCIBCFLH_01254 8.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KCIBCFLH_01255 2e-164 yocS S -transporter
KCIBCFLH_01257 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KCIBCFLH_01258 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KCIBCFLH_01259 4.5e-155 yicC S stress-induced protein
KCIBCFLH_01260 7.7e-46 ylzA S Belongs to the UPF0296 family
KCIBCFLH_01261 1.3e-108 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KCIBCFLH_01262 3.4e-29 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KCIBCFLH_01263 4.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCIBCFLH_01264 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCIBCFLH_01265 1.3e-82 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KCIBCFLH_01266 5.3e-178 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCIBCFLH_01267 4.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCIBCFLH_01268 3.5e-140 stp 3.1.3.16 T phosphatase
KCIBCFLH_01269 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KCIBCFLH_01270 1.6e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KCIBCFLH_01271 5.9e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KCIBCFLH_01272 6.8e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
KCIBCFLH_01273 5e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KCIBCFLH_01274 3e-248 L PFAM Transposase, IS4-like
KCIBCFLH_01275 6.5e-60 asp S protein conserved in bacteria
KCIBCFLH_01276 1.5e-305 yloV S kinase related to dihydroxyacetone kinase
KCIBCFLH_01277 2.5e-118 sdaAB 4.3.1.17 E L-serine dehydratase
KCIBCFLH_01278 7.7e-155 sdaAA 4.3.1.17 E L-serine dehydratase
KCIBCFLH_01279 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCIBCFLH_01280 7.4e-98 fapR 5.3.1.23 Q Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KCIBCFLH_01281 7.8e-208 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KCIBCFLH_01282 4.3e-164 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KCIBCFLH_01283 1.4e-128 IQ reductase
KCIBCFLH_01284 3.7e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCIBCFLH_01285 2.4e-133 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KCIBCFLH_01286 0.0 smc D Required for chromosome condensation and partitioning
KCIBCFLH_01287 2.5e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KCIBCFLH_01288 2.6e-52 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KCIBCFLH_01289 5.1e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCIBCFLH_01290 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KCIBCFLH_01291 4.7e-35 ylqC S Belongs to the UPF0109 family
KCIBCFLH_01292 8.3e-61 ylqD S YlqD protein
KCIBCFLH_01293 1.7e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCIBCFLH_01294 8.9e-141 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KCIBCFLH_01295 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KCIBCFLH_01296 1.6e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KCIBCFLH_01297 2.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCIBCFLH_01298 8.7e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCIBCFLH_01299 4.4e-233 CP_1081 D nuclear chromosome segregation
KCIBCFLH_01300 3.6e-45 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KCIBCFLH_01301 2.1e-213 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KCIBCFLH_01302 2.8e-168 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KCIBCFLH_01303 6.2e-165 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KCIBCFLH_01304 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCIBCFLH_01306 5.1e-170 xerC L tyrosine recombinase XerC
KCIBCFLH_01307 2.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KCIBCFLH_01308 2.3e-225 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KCIBCFLH_01309 8.6e-134 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KCIBCFLH_01310 4.4e-62 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KCIBCFLH_01311 4e-75 flgC N Belongs to the flagella basal body rod proteins family
KCIBCFLH_01312 9.9e-41 fliE N Flagellar hook-basal body complex protein FliE
KCIBCFLH_01313 1.6e-248 fliF N The M ring may be actively involved in energy transduction
KCIBCFLH_01314 2.7e-164 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KCIBCFLH_01315 1.9e-130 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KCIBCFLH_01316 1.2e-247 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KCIBCFLH_01317 8.1e-73 fliJ N Flagellar biosynthesis chaperone
KCIBCFLH_01318 1.3e-47 ylxF S MgtE intracellular N domain
KCIBCFLH_01319 0.0 fliK N Flagellar hook-length control
KCIBCFLH_01320 1.3e-103 flgD N Required for flagellar hook formation. May act as a scaffolding protein
KCIBCFLH_01321 4e-75 flg N Putative flagellar
KCIBCFLH_01322 3.4e-135 flgG N Flagellar basal body rod
KCIBCFLH_01323 9.3e-66 fliL N Controls the rotational direction of flagella during chemotaxis
KCIBCFLH_01324 9.9e-183 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KCIBCFLH_01325 4.3e-195 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KCIBCFLH_01326 3.2e-59 cheB 3.1.1.61, 3.5.1.44 T response regulator
KCIBCFLH_01327 1.2e-115 fliZ N Flagellar biosynthesis protein, FliO
KCIBCFLH_01328 2e-107 fliP N Plays a role in the flagellum-specific transport system
KCIBCFLH_01329 1.5e-37 fliQ N Role in flagellar biosynthesis
KCIBCFLH_01330 2.5e-133 fliR N Flagellar biosynthetic protein FliR
KCIBCFLH_01331 3.4e-189 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCIBCFLH_01332 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KCIBCFLH_01333 8.4e-207 flhF N Flagellar biosynthesis regulator FlhF
KCIBCFLH_01334 3e-156 flhG D Belongs to the ParA family
KCIBCFLH_01335 9.6e-118 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KCIBCFLH_01336 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KCIBCFLH_01337 1.4e-69 cheW NT COG0835 Chemotaxis signal transduction protein
KCIBCFLH_01338 4e-113 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KCIBCFLH_01339 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KCIBCFLH_01340 1.8e-136 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCIBCFLH_01341 8e-86 ylxL
KCIBCFLH_01342 6.2e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KCIBCFLH_01343 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCIBCFLH_01344 1.5e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KCIBCFLH_01345 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KCIBCFLH_01346 1.6e-148 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCIBCFLH_01347 3.8e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KCIBCFLH_01348 7.2e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KCIBCFLH_01349 7.4e-236 rasP M zinc metalloprotease
KCIBCFLH_01350 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KCIBCFLH_01351 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCIBCFLH_01352 9.2e-83 rimP S Required for maturation of 30S ribosomal subunits
KCIBCFLH_01353 3.1e-223 nusA K Participates in both transcription termination and antitermination
KCIBCFLH_01354 8.2e-45 ylxR K nucleic-acid-binding protein implicated in transcription termination
KCIBCFLH_01355 2.9e-48 ylxQ J ribosomal protein
KCIBCFLH_01356 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KCIBCFLH_01357 1.1e-43 ylxP S protein conserved in bacteria
KCIBCFLH_01358 3.2e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KCIBCFLH_01359 5.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KCIBCFLH_01360 3.8e-184 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KCIBCFLH_01361 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KCIBCFLH_01362 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KCIBCFLH_01363 5.2e-209 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KCIBCFLH_01364 5.2e-234 pepR S Belongs to the peptidase M16 family
KCIBCFLH_01365 6.2e-38 ymxH S YlmC YmxH family
KCIBCFLH_01366 1.3e-190 dpaA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KCIBCFLH_01367 7.4e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KCIBCFLH_01368 3.7e-188 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCIBCFLH_01369 2e-225 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KCIBCFLH_01370 1.5e-158 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCIBCFLH_01371 0.0 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCIBCFLH_01372 2e-132 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KCIBCFLH_01373 3.3e-35 S YlzJ-like protein
KCIBCFLH_01374 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KCIBCFLH_01375 1.3e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KCIBCFLH_01376 7.8e-288 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KCIBCFLH_01377 9e-187 yufP S Belongs to the binding-protein-dependent transport system permease family
KCIBCFLH_01378 4.9e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KCIBCFLH_01379 9.4e-239 ymfF S Peptidase M16
KCIBCFLH_01380 1.2e-244 ymfH S zinc protease
KCIBCFLH_01381 1e-145 1.1.1.100 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KCIBCFLH_01382 6.4e-41 ymfJ S Protein of unknown function (DUF3243)
KCIBCFLH_01383 9.9e-146 ymfK S Protein of unknown function (DUF3388)
KCIBCFLH_01384 3.7e-158 ymfM S protein conserved in bacteria
KCIBCFLH_01385 1.1e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCIBCFLH_01386 2.1e-227 cinA 3.5.1.42 S Belongs to the CinA family
KCIBCFLH_01387 2.1e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCIBCFLH_01388 2.5e-217 rny S Endoribonuclease that initiates mRNA decay
KCIBCFLH_01389 6.5e-153 ymdB S protein conserved in bacteria
KCIBCFLH_01390 3.3e-37 spoVS S Stage V sporulation protein S
KCIBCFLH_01391 5.1e-170 yegQ O Peptidase U32
KCIBCFLH_01392 3.1e-250 yegQ O COG0826 Collagenase and related proteases
KCIBCFLH_01393 4.9e-210 E Amino acid permease
KCIBCFLH_01394 0.0 KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KCIBCFLH_01395 2.8e-290 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KCIBCFLH_01396 1.6e-263 patA 2.6.1.11, 2.6.1.17, 2.6.1.82 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCIBCFLH_01397 1.8e-300 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KCIBCFLH_01398 6.8e-48 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KCIBCFLH_01399 3.6e-99 cotE S Outer spore coat protein E (CotE)
KCIBCFLH_01400 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCIBCFLH_01401 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCIBCFLH_01402 5.5e-40 yhjA S Excalibur calcium-binding domain
KCIBCFLH_01403 2.4e-22 2.1.1.80, 3.1.1.61 S protein secretion by the type IV secretion system
KCIBCFLH_01407 1.4e-192 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCIBCFLH_01408 1.2e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KCIBCFLH_01410 4.2e-175 spoVK O stage V sporulation protein K
KCIBCFLH_01411 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCIBCFLH_01412 7.5e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KCIBCFLH_01413 1.1e-167 polA 2.7.7.7 L 5'3' exonuclease
KCIBCFLH_01415 3.6e-27 ypeQ S Zinc-finger
KCIBCFLH_01416 1.2e-31 cspD K Cold-shock protein
KCIBCFLH_01417 1.2e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KCIBCFLH_01418 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KCIBCFLH_01419 4.4e-83
KCIBCFLH_01420 1.9e-118 ypgQ S phosphohydrolase
KCIBCFLH_01421 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KCIBCFLH_01422 6.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
KCIBCFLH_01423 5.6e-74 yphP S Belongs to the UPF0403 family
KCIBCFLH_01424 8.1e-105 ypjP S YpjP-like protein
KCIBCFLH_01425 3.1e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KCIBCFLH_01426 1.8e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCIBCFLH_01427 1.9e-110 hlyIII S protein, Hemolysin III
KCIBCFLH_01428 4.7e-140 ypmR E COG2755 Lysophospholipase L1 and related esterases
KCIBCFLH_01429 1.2e-97 ypmS S protein conserved in bacteria
KCIBCFLH_01430 2.5e-269 rsmF 2.1.1.176, 2.1.1.178 J RNA-binding PUA-like domain of methyltransferase RsmF
KCIBCFLH_01431 2.1e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCIBCFLH_01432 3.3e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KCIBCFLH_01433 8.8e-18 S Protein of unknown function (Tiny_TM_bacill)
KCIBCFLH_01434 6e-207 NT CHASE3 domain
KCIBCFLH_01435 3e-36 yozE S Belongs to the UPF0346 family
KCIBCFLH_01436 1.3e-116 yodN
KCIBCFLH_01437 1.3e-24 yozD S YozD-like protein
KCIBCFLH_01439 6.9e-147 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KCIBCFLH_01440 1.1e-278 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KCIBCFLH_01441 3.9e-67 ypoP K transcriptional
KCIBCFLH_01442 2e-100 ykwD J protein with SCP PR1 domains
KCIBCFLH_01443 5.4e-248 norM V Multidrug efflux pump
KCIBCFLH_01445 8.3e-190 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KCIBCFLH_01446 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KCIBCFLH_01447 9.2e-134 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KCIBCFLH_01448 6.3e-106 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KCIBCFLH_01450 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KCIBCFLH_01451 2e-103 K Transcriptional regulator
KCIBCFLH_01452 1.6e-58 4.4.1.5 E lactoylglutathione lyase activity
KCIBCFLH_01453 4.6e-238 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KCIBCFLH_01454 2.7e-141 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KCIBCFLH_01455 8.8e-229 ymfD EGP Major facilitator Superfamily
KCIBCFLH_01456 1.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCIBCFLH_01457 1.2e-255 arlS 2.7.13.3 T Histidine kinase
KCIBCFLH_01458 1.6e-52 yozR S COG0071 Molecular chaperone (small heat shock protein)
KCIBCFLH_01459 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KCIBCFLH_01460 9.5e-202 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KCIBCFLH_01461 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KCIBCFLH_01462 5.9e-92 rok S Repressor of ComK
KCIBCFLH_01463 4.4e-114 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCIBCFLH_01465 1.5e-161 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KCIBCFLH_01466 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCIBCFLH_01467 3.5e-193 yceA S Belongs to the UPF0176 family
KCIBCFLH_01468 1.6e-128 yoqW S Belongs to the SOS response-associated peptidase family
KCIBCFLH_01469 8.3e-105 thiT S Proton-coupled thiamine transporter YuaJ
KCIBCFLH_01470 5.7e-58 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KCIBCFLH_01471 2.1e-79 S Domain in cystathionine beta-synthase and other proteins.
KCIBCFLH_01472 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KCIBCFLH_01473 9.1e-107 yocH CBM50 M COG1388 FOG LysM repeat
KCIBCFLH_01474 0.0 topB2 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCIBCFLH_01475 3.8e-254 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KCIBCFLH_01476 2.6e-112 E Lysine exporter protein LysE YggA
KCIBCFLH_01477 1.1e-178 corA P Mg2 transporter protein
KCIBCFLH_01478 3.3e-69 S CHY zinc finger
KCIBCFLH_01479 9e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KCIBCFLH_01480 8.1e-111 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KCIBCFLH_01481 2.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCIBCFLH_01482 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KCIBCFLH_01483 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KCIBCFLH_01484 1.1e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KCIBCFLH_01485 6.6e-139 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KCIBCFLH_01486 1e-119 hisE 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KCIBCFLH_01487 5.9e-41 yedF O Belongs to the sulfur carrier protein TusA family
KCIBCFLH_01488 1.5e-241 yedE S Sulphur transport
KCIBCFLH_01489 3.2e-175 rarD S -transporter
KCIBCFLH_01490 9.1e-221 ktrB P COG0168 Trk-type K transport systems, membrane components
KCIBCFLH_01491 1.7e-122 P COG0569 K transport systems, NAD-binding component
KCIBCFLH_01492 3e-136 ykrK S Domain of unknown function (DUF1836)
KCIBCFLH_01493 1e-17
KCIBCFLH_01494 3.6e-48 yxcD S Protein of unknown function (DUF2653)
KCIBCFLH_01495 8.6e-218 yeaN P COG2807 Cyanate permease
KCIBCFLH_01496 0.0 ubiB S ABC1 family
KCIBCFLH_01497 4.7e-24 S ATP synthase, subunit b
KCIBCFLH_01498 2.1e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCIBCFLH_01501 2.7e-31 cspB K Cold shock
KCIBCFLH_01502 1.3e-196 L DDE superfamily endonuclease
KCIBCFLH_01503 9.4e-118 folE 3.5.4.16 H GTP cyclohydrolase
KCIBCFLH_01504 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_01505 6.7e-165 trxB_2 1.8.1.9 C FAD dependent oxidoreductase
KCIBCFLH_01506 5.3e-44 S Protein of unknown function (DUF1292)
KCIBCFLH_01507 8.1e-48 yxiS
KCIBCFLH_01508 0.0 bceB V ABC transporter (permease)
KCIBCFLH_01509 1.7e-134 bceA V ABC transporter, ATP-binding protein
KCIBCFLH_01510 4.7e-185 bceS 2.7.13.3 T Signal transduction histidine kinase
KCIBCFLH_01511 4.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCIBCFLH_01512 1.8e-170 S Protein of unknown function (DUF1672)
KCIBCFLH_01513 3.5e-114 S Protein of unknown function (DUF1672)
KCIBCFLH_01514 3.4e-11 S Protein of unknown function (DUF1672)
KCIBCFLH_01515 0.0
KCIBCFLH_01516 4.3e-18 L PFAM Transposase, IS4-like
KCIBCFLH_01517 1.1e-71 ybzH K Helix-turn-helix domain
KCIBCFLH_01518 2e-198 ybcL EGP Major facilitator Superfamily
KCIBCFLH_01520 2e-194 yxaB GM Polysaccharide pyruvyl transferase
KCIBCFLH_01521 1.3e-16
KCIBCFLH_01522 1.6e-239 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KCIBCFLH_01523 3.6e-202 yetN S Protein of unknown function (DUF3900)
KCIBCFLH_01524 1.1e-150
KCIBCFLH_01527 5.9e-239 ywoD EGP Major facilitator superfamily
KCIBCFLH_01528 2.5e-52 iscA S Heme biosynthesis protein HemY
KCIBCFLH_01529 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KCIBCFLH_01530 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KCIBCFLH_01531 7.2e-43 S Small, acid-soluble spore proteins, alpha/beta type
KCIBCFLH_01532 5.8e-62 S Effector of murein hydrolase LrgA
KCIBCFLH_01533 4.4e-110 M effector of murein hydrolase
KCIBCFLH_01534 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KCIBCFLH_01535 5.3e-115 M lytic transglycosylase activity
KCIBCFLH_01536 6.2e-09 S membrane
KCIBCFLH_01537 8.6e-19 sspP S Belongs to the SspP family
KCIBCFLH_01538 2.6e-39
KCIBCFLH_01539 6.4e-240 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KCIBCFLH_01540 2.6e-18 sspO S Belongs to the SspO family
KCIBCFLH_01541 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCIBCFLH_01543 1e-19 sspN S Small acid-soluble spore protein N family
KCIBCFLH_01544 4.1e-31 tlp S Belongs to the Tlp family
KCIBCFLH_01545 4.3e-64 yneP S thioesterase
KCIBCFLH_01546 2.5e-52 yneQ
KCIBCFLH_01547 3.7e-53 yneR S Belongs to the HesB IscA family
KCIBCFLH_01548 9.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KCIBCFLH_01549 1.9e-71 yccU S CoA-binding protein
KCIBCFLH_01550 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCIBCFLH_01551 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCIBCFLH_01552 2.8e-148
KCIBCFLH_01553 1.9e-29 yjjL G Major facilitator superfamily
KCIBCFLH_01554 1.3e-27 yjjL G Major facilitator superfamily
KCIBCFLH_01555 1e-23 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KCIBCFLH_01556 4.9e-108 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KCIBCFLH_01557 9.6e-37 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
KCIBCFLH_01558 3e-92 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
KCIBCFLH_01559 4.6e-307 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
KCIBCFLH_01560 7.9e-69 E Glyoxalase
KCIBCFLH_01565 1.3e-199 yrpB 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KCIBCFLH_01567 3.6e-102 5.1.3.34 S oxidoreductase activity
KCIBCFLH_01568 9.1e-95 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KCIBCFLH_01570 2.6e-197 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
KCIBCFLH_01571 2.7e-162 2.1.1.144, 2.1.1.197 S Methyltransferase domain
KCIBCFLH_01572 2.1e-08
KCIBCFLH_01575 4.2e-138 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KCIBCFLH_01576 2e-94 yvbK 3.1.3.25 K acetyltransferase
KCIBCFLH_01577 6.1e-93 VPA1573 J acetyltransferase
KCIBCFLH_01578 3.1e-69 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) family
KCIBCFLH_01579 1.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
KCIBCFLH_01580 6.4e-124 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KCIBCFLH_01581 7.8e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KCIBCFLH_01582 2.8e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KCIBCFLH_01583 3.4e-123 yflK S protein conserved in bacteria
KCIBCFLH_01584 4.3e-42 S COG NOG14552 non supervised orthologous group
KCIBCFLH_01585 2.6e-42
KCIBCFLH_01587 2.7e-82 2.3.1.57 K Acetyltransferase (GNAT) domain
KCIBCFLH_01588 1.2e-214 S Psort location CytoplasmicMembrane, score
KCIBCFLH_01589 1.8e-121 yfiR K Bacterial regulatory proteins, tetR family
KCIBCFLH_01590 3.4e-200 yfiS EGP Major facilitator Superfamily
KCIBCFLH_01591 2e-135 thiX 2.7.1.50 P binding-protein-dependent transport systems inner membrane component
KCIBCFLH_01592 1.5e-183 nrtA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KCIBCFLH_01593 4.3e-73 S Glyoxalase bleomycin resistance protein dioxygenase
KCIBCFLH_01594 3.3e-149 yitD 4.4.1.19 S synthase
KCIBCFLH_01595 3.3e-129 comB 3.1.3.71 H Belongs to the ComB family
KCIBCFLH_01596 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KCIBCFLH_01597 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KCIBCFLH_01598 7.4e-109
KCIBCFLH_01599 1.1e-133 mta K transcriptional
KCIBCFLH_01600 2.3e-270 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
KCIBCFLH_01601 1.1e-175 yjlA EG Putative multidrug resistance efflux transporter
KCIBCFLH_01602 2e-188 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KCIBCFLH_01603 1.1e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KCIBCFLH_01604 6.7e-72 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KCIBCFLH_01605 2.3e-111 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KCIBCFLH_01606 2.1e-260 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KCIBCFLH_01607 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KCIBCFLH_01608 2e-189 kefA M Mechanosensitive ion channel
KCIBCFLH_01609 3e-192 S COG0491 Zn-dependent hydrolases, including glyoxylases
KCIBCFLH_01610 4.1e-56 I SCP-2 sterol transfer family
KCIBCFLH_01611 1.3e-170 nrdB 1.17.4.1 F Ribonucleotide reductase, small chain
KCIBCFLH_01612 1.3e-16 nrdB 1.17.4.1 F Ribonucleotide reductase, small chain
KCIBCFLH_01613 1.2e-103 S Appr-1'-p processing enzyme
KCIBCFLH_01614 2e-25 sspH S small acid-soluble spore protein
KCIBCFLH_01615 3.1e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KCIBCFLH_01616 2.4e-209 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
KCIBCFLH_01617 4.5e-288 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KCIBCFLH_01618 1.9e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KCIBCFLH_01619 3.9e-150 S Sucrose-6F-phosphate phosphohydrolase
KCIBCFLH_01620 2.7e-97 yozB S membrane
KCIBCFLH_01621 2e-59
KCIBCFLH_01622 1.4e-78 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCIBCFLH_01623 1.8e-181 ldh1 1.1.1.27 C Belongs to the LDH MDH superfamily
KCIBCFLH_01624 2.9e-131 IQ Enoyl-(Acyl carrier protein) reductase
KCIBCFLH_01625 3.6e-216 fsr P COG0477 Permeases of the major facilitator superfamily
KCIBCFLH_01626 7.4e-79 sleB 3.5.1.28 M Cell wall
KCIBCFLH_01627 2e-148 xth 3.1.11.2 L exodeoxyribonuclease III
KCIBCFLH_01628 1.1e-156 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KCIBCFLH_01629 1.3e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KCIBCFLH_01630 2e-192 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KCIBCFLH_01631 6.8e-212 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCIBCFLH_01632 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCIBCFLH_01633 4.8e-198 G Glycosyl hydrolases family 15
KCIBCFLH_01635 3e-22 S YpzG-like protein
KCIBCFLH_01636 2.5e-89 Q protein disulfide oxidoreductase activity
KCIBCFLH_01637 1.8e-95 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KCIBCFLH_01638 7.4e-120 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KCIBCFLH_01639 1.5e-228 mntH P H( )-stimulated, divalent metal cation uptake system
KCIBCFLH_01640 1.4e-75 dps P Ferritin-like domain
KCIBCFLH_01641 1.6e-79 V VanZ like family
KCIBCFLH_01642 1.5e-169 yhcI S ABC-2 family transporter protein
KCIBCFLH_01643 8.2e-171 ydbJ V ABC transporter, ATP-binding protein
KCIBCFLH_01644 6.3e-57
KCIBCFLH_01645 1.4e-167 murB 1.3.1.98 M cell wall formation
KCIBCFLH_01646 7e-92 S Protein of unknown function (DUF1189)
KCIBCFLH_01647 2.4e-37 S Protein of unknown function (DUF1450)
KCIBCFLH_01648 2.7e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KCIBCFLH_01649 1.6e-70 I MaoC like domain
KCIBCFLH_01650 1.4e-80 I N-terminal half of MaoC dehydratase
KCIBCFLH_01651 1.8e-156 IQ Enoyl-(Acyl carrier protein) reductase
KCIBCFLH_01652 5.9e-263 dld 1.1.1.303, 1.1.1.4, 1.1.2.4 C Glycolate oxidase subunit
KCIBCFLH_01654 4.2e-200 selU S tRNA 2-selenouridine synthase
KCIBCFLH_01655 3.1e-195 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
KCIBCFLH_01656 6.5e-136 T Calcineurin-like phosphoesterase superfamily domain
KCIBCFLH_01657 2.9e-193 yraQ S Predicted permease
KCIBCFLH_01658 1.1e-231 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCIBCFLH_01659 3.2e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KCIBCFLH_01660 6.4e-73 yjlC S Protein of unknown function (DUF1641)
KCIBCFLH_01661 2.8e-221 yjlD 1.6.99.3 C NADH dehydrogenase
KCIBCFLH_01662 2e-230 nrnB S phosphohydrolase (DHH superfamily)
KCIBCFLH_01663 4.8e-128 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCIBCFLH_01664 2.7e-130 yvpB NU protein conserved in bacteria
KCIBCFLH_01665 1.1e-50 tnrA K transcriptional
KCIBCFLH_01666 1.4e-109 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KCIBCFLH_01667 1.1e-23 S Virus attachment protein p12 family
KCIBCFLH_01668 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KCIBCFLH_01669 1.3e-47 feoA P COG1918 Fe2 transport system protein A
KCIBCFLH_01670 5.9e-227 dapL 2.6.1.83 E Aminotransferase
KCIBCFLH_01671 2.2e-265 argH 4.3.2.1 E argininosuccinate lyase
KCIBCFLH_01672 4.8e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KCIBCFLH_01673 7.7e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCIBCFLH_01674 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KCIBCFLH_01675 6e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KCIBCFLH_01676 1.1e-225 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KCIBCFLH_01677 1.5e-141 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KCIBCFLH_01678 3.1e-234 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KCIBCFLH_01679 1.9e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCIBCFLH_01681 6.5e-81
KCIBCFLH_01682 1.2e-154 yjqC P Catalase
KCIBCFLH_01683 4e-86
KCIBCFLH_01684 2.3e-30 cspD K Cold shock
KCIBCFLH_01686 1.2e-174 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KCIBCFLH_01687 8.6e-284 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KCIBCFLH_01688 3.9e-107 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KCIBCFLH_01689 2.1e-76 yneK S Protein of unknown function (DUF2621)
KCIBCFLH_01690 4.6e-77 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KCIBCFLH_01691 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KCIBCFLH_01692 9.9e-129 ccdA O cytochrome c biogenesis protein
KCIBCFLH_01693 6.8e-28 yneF S UPF0154 protein
KCIBCFLH_01694 4.2e-77 yneE S Sporulation inhibitor of replication protein sirA
KCIBCFLH_01695 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KCIBCFLH_01696 2.8e-32 ynzC S UPF0291 protein
KCIBCFLH_01697 1.4e-116 yneB L resolvase
KCIBCFLH_01698 4.4e-58 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KCIBCFLH_01699 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCIBCFLH_01701 3.4e-51 3.5.1.28 M hmm pf01520
KCIBCFLH_01702 2.7e-22 S SPP1 phage holin
KCIBCFLH_01703 1.4e-14 S Haemolysin XhlA
KCIBCFLH_01704 2.5e-13
KCIBCFLH_01705 8.3e-10
KCIBCFLH_01708 1.9e-97 S Calcineurin-like phosphoesterase
KCIBCFLH_01709 3.9e-76 S Prophage endopeptidase tail
KCIBCFLH_01710 7.7e-48 S Phage tail protein
KCIBCFLH_01711 8.3e-175 D Phage tail tape measure protein
KCIBCFLH_01714 1e-28 S Phage tail tube protein
KCIBCFLH_01715 6.2e-08
KCIBCFLH_01716 4.8e-17
KCIBCFLH_01717 2.5e-21 S Phage head-tail joining protein
KCIBCFLH_01718 2.6e-24 S Phage gp6-like head-tail connector protein
KCIBCFLH_01719 4.3e-89 S Phage capsid family
KCIBCFLH_01720 1.3e-67 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
KCIBCFLH_01721 5.8e-135 S TIGRFAM phage portal protein, HK97 family
KCIBCFLH_01722 2.4e-252 S Terminase
KCIBCFLH_01723 3.2e-23
KCIBCFLH_01724 9.1e-17 V HNH nucleases
KCIBCFLH_01725 1.7e-21
KCIBCFLH_01726 4.7e-70 L Phage integrase family
KCIBCFLH_01727 1.4e-51 wecC 1.1.1.336 M UDP-N-acetyl-D-mannosamine dehydrogenase activity
KCIBCFLH_01728 7e-55 K BRO family, N-terminal domain
KCIBCFLH_01733 1.4e-09 S Phage-like element PBSX protein XtrA
KCIBCFLH_01734 9.5e-77 L Replication initiation and membrane attachment
KCIBCFLH_01739 1.3e-28
KCIBCFLH_01740 2e-57
KCIBCFLH_01741 6.6e-10 K Helix-turn-helix XRE-family like proteins
KCIBCFLH_01742 1.5e-28 K transcriptional
KCIBCFLH_01743 5.5e-71 ligA 2.7.7.7, 6.5.1.2 L PFAM BRCA1 C Terminus (BRCT) domain
KCIBCFLH_01744 8.3e-46 polC_1 2.7.7.7 L DNA polymerase III, epsilon subunit
KCIBCFLH_01745 3.9e-66 K DNA binding
KCIBCFLH_01746 4.8e-101 dam2 2.1.1.72 L DNA methyltransferase
KCIBCFLH_01747 8.3e-45 E IrrE N-terminal-like domain
KCIBCFLH_01748 1.1e-137 L Arm DNA-binding domain
KCIBCFLH_01749 4.4e-263 glnA 6.3.1.2 E glutamine synthetase
KCIBCFLH_01750 1.5e-65 glnR K transcriptional
KCIBCFLH_01751 0.0 S Dynamin family
KCIBCFLH_01752 2.6e-34
KCIBCFLH_01753 1.3e-131 f42a O prohibitin homologues
KCIBCFLH_01754 1.2e-233 pbuX F xanthine
KCIBCFLH_01755 2.5e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KCIBCFLH_01756 2.7e-301 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KCIBCFLH_01757 2.2e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KCIBCFLH_01758 9e-47 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KCIBCFLH_01759 1.4e-101 ypsA S Belongs to the UPF0398 family
KCIBCFLH_01760 8.3e-46 cotD S Inner spore coat protein D
KCIBCFLH_01761 5.1e-256 yprB L RNase_H superfamily
KCIBCFLH_01762 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KCIBCFLH_01763 4.2e-77 hspX O Belongs to the small heat shock protein (HSP20) family
KCIBCFLH_01764 1e-45 yppG S YppG-like protein
KCIBCFLH_01765 7e-62 yppE S Bacterial domain of unknown function (DUF1798)
KCIBCFLH_01769 1.9e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KCIBCFLH_01770 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCIBCFLH_01771 2.6e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCIBCFLH_01772 3.9e-130 dnaD L DNA replication protein DnaD
KCIBCFLH_01773 2.2e-262 asnS 6.1.1.22 J asparaginyl-tRNA
KCIBCFLH_01774 1.7e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KCIBCFLH_01775 1.7e-78 ypmB S protein conserved in bacteria
KCIBCFLH_01776 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KCIBCFLH_01777 7.9e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KCIBCFLH_01778 3.5e-160 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KCIBCFLH_01779 6.4e-151 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KCIBCFLH_01780 1.4e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KCIBCFLH_01781 1.9e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KCIBCFLH_01782 1.7e-221 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KCIBCFLH_01783 3.3e-132 bshB1 S proteins, LmbE homologs
KCIBCFLH_01784 2.6e-149 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KCIBCFLH_01785 9.9e-58 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KCIBCFLH_01786 7e-161 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KCIBCFLH_01787 3.1e-81 queT S QueT transporter
KCIBCFLH_01788 1.3e-101 yugP S Zn-dependent protease
KCIBCFLH_01789 1.8e-142 ypjB S sporulation protein
KCIBCFLH_01790 2.5e-109 ypjA S membrane
KCIBCFLH_01791 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KCIBCFLH_01792 1.2e-126 petB C COG1290 Cytochrome b subunit of the bc complex
KCIBCFLH_01793 1e-98 qcrA C Menaquinol-cytochrome c reductase
KCIBCFLH_01794 2e-85 ypiF S Protein of unknown function (DUF2487)
KCIBCFLH_01795 1.7e-99 ypiB S Belongs to the UPF0302 family
KCIBCFLH_01796 8.5e-240 S COG0457 FOG TPR repeat
KCIBCFLH_01797 2.3e-240 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KCIBCFLH_01798 1.3e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KCIBCFLH_01799 9.3e-211 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCIBCFLH_01800 2.9e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KCIBCFLH_01801 6.4e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KCIBCFLH_01802 2.9e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KCIBCFLH_01803 3.2e-144 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KCIBCFLH_01804 1.5e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KCIBCFLH_01805 1.5e-175 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KCIBCFLH_01806 7.5e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KCIBCFLH_01807 1.8e-142 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KCIBCFLH_01808 2.8e-32 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KCIBCFLH_01809 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KCIBCFLH_01810 4.1e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KCIBCFLH_01811 1.2e-137 yphF
KCIBCFLH_01812 3.3e-08 yphE S Protein of unknown function (DUF2768)
KCIBCFLH_01813 7.8e-191 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KCIBCFLH_01814 4.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KCIBCFLH_01815 1.2e-18 yphA
KCIBCFLH_01816 7.3e-14 S YpzI-like protein
KCIBCFLH_01817 1e-204 rpsA 1.17.7.4 J Ribosomal protein S1
KCIBCFLH_01818 1.2e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KCIBCFLH_01819 2.5e-118 ypfA M Flagellar protein YcgR
KCIBCFLH_01820 2.9e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KCIBCFLH_01821 3.9e-150 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KCIBCFLH_01822 2e-126 prsW S Involved in the degradation of specific anti-sigma factors
KCIBCFLH_01823 4.3e-191 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KCIBCFLH_01824 1.2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KCIBCFLH_01825 2.7e-111 mecB NOT Negative regulator of genetic competence (MecA)
KCIBCFLH_01826 2.4e-144 ypbG S Calcineurin-like phosphoesterase superfamily domain
KCIBCFLH_01827 2.8e-32 cotJA S Spore coat associated protein JA (CotJA)
KCIBCFLH_01828 9.5e-45 cotJB S CotJB protein
KCIBCFLH_01829 2.3e-104 cotJC P Spore Coat
KCIBCFLH_01830 2e-79 ypbF S Protein of unknown function (DUF2663)
KCIBCFLH_01832 2.9e-102 ypbD S metal-dependent membrane protease
KCIBCFLH_01833 4.1e-286 recQ 3.6.4.12 L DNA helicase
KCIBCFLH_01834 3.4e-205 ypbB 5.1.3.1 S protein conserved in bacteria
KCIBCFLH_01835 4.7e-41 fer C Ferredoxin
KCIBCFLH_01836 4.3e-98 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KCIBCFLH_01837 2.5e-135 M COG0739 Membrane proteins related to metalloendopeptidases
KCIBCFLH_01838 0.0 resE 2.7.13.3 T Histidine kinase
KCIBCFLH_01839 3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCIBCFLH_01840 5.4e-228 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KCIBCFLH_01841 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KCIBCFLH_01842 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KCIBCFLH_01843 9.9e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCIBCFLH_01844 6.4e-88 spmB S Spore maturation protein
KCIBCFLH_01845 5.2e-96 spmA S Spore maturation protein
KCIBCFLH_01846 1e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KCIBCFLH_01847 1.5e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCIBCFLH_01848 1.9e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCIBCFLH_01850 9e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCIBCFLH_01851 1.4e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KCIBCFLH_01852 4.9e-271 spoVAF EG Stage V sporulation protein AF
KCIBCFLH_01853 6.6e-107 spoVAEA S Stage V sporulation protein AE
KCIBCFLH_01854 1.3e-67 spoVAB S Stage V sporulation protein AB
KCIBCFLH_01855 1.6e-111 spoVAA S Stage V sporulation protein AA
KCIBCFLH_01856 1.1e-133 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCIBCFLH_01857 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KCIBCFLH_01858 2.5e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KCIBCFLH_01859 3.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KCIBCFLH_01860 2.7e-168 xerD L recombinase XerD
KCIBCFLH_01861 1.6e-85 fur P Belongs to the Fur family
KCIBCFLH_01862 1.1e-105 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KCIBCFLH_01863 1.9e-225 yqxK 3.6.4.12 L DNA helicase
KCIBCFLH_01864 1.6e-97 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KCIBCFLH_01866 3e-162 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KCIBCFLH_01869 2.2e-106 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KCIBCFLH_01870 3.5e-211 yaaN P Belongs to the TelA family
KCIBCFLH_01871 6.3e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KCIBCFLH_01872 1.6e-242 yaaH_2 M Glycoside Hydrolase Family
KCIBCFLH_01873 2.7e-55 S YolD-like protein
KCIBCFLH_01874 2e-241 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCIBCFLH_01875 6.1e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KCIBCFLH_01876 7.7e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCIBCFLH_01877 2.2e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KCIBCFLH_01878 9.3e-294 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCIBCFLH_01879 1.8e-223 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCIBCFLH_01880 3.5e-77 cheW NT COG0835 Chemotaxis signal transduction protein
KCIBCFLH_01881 3.3e-203 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KCIBCFLH_01882 9e-92 yqjB S protein conserved in bacteria
KCIBCFLH_01883 9.3e-77 yqiW S Belongs to the UPF0403 family
KCIBCFLH_01884 2.9e-165 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KCIBCFLH_01885 3.3e-212 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KCIBCFLH_01886 3.9e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KCIBCFLH_01887 3.8e-187 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KCIBCFLH_01888 2.6e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KCIBCFLH_01889 1.5e-208 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KCIBCFLH_01890 7e-292 bkdR 2.7.13.3 KT Transcriptional regulator
KCIBCFLH_01891 1.2e-36 yqzF S Protein of unknown function (DUF2627)
KCIBCFLH_01892 5.1e-136 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KCIBCFLH_01893 2.8e-140 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KCIBCFLH_01895 1.2e-241 rseP 3.4.21.116 M Stage IV sporulation protein B
KCIBCFLH_01896 1.9e-295 recN L May be involved in recombinational repair of damaged DNA
KCIBCFLH_01897 1.2e-79 argR K Regulates arginine biosynthesis genes
KCIBCFLH_01898 1.1e-147 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KCIBCFLH_01899 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCIBCFLH_01900 3.3e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KCIBCFLH_01901 3.1e-31 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KCIBCFLH_01902 8.4e-238 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KCIBCFLH_01903 1.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCIBCFLH_01904 1.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCIBCFLH_01905 1.9e-68 yqhY S protein conserved in bacteria
KCIBCFLH_01906 3.7e-257 accC 6.3.4.14, 6.3.4.6, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KCIBCFLH_01907 5.2e-81 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KCIBCFLH_01908 5.5e-79 spoIIIAH S SpoIIIAH-like protein
KCIBCFLH_01909 2.5e-110 spoIIIAG S stage III sporulation protein AG
KCIBCFLH_01910 1.1e-107 spoIIIAF S stage III sporulation protein AF
KCIBCFLH_01911 3.4e-190 spoIIIAE S stage III sporulation protein AE
KCIBCFLH_01912 3.8e-58 spoIIIAD S Stage III sporulation protein AD
KCIBCFLH_01913 1.4e-27 spoIIIAC S stage III sporulation protein AC
KCIBCFLH_01914 1.7e-85 spoIIIAB S Stage III sporulation protein
KCIBCFLH_01915 1e-170 spoIIIAA S stage III sporulation protein AA
KCIBCFLH_01916 1.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCIBCFLH_01917 1.2e-162 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KCIBCFLH_01918 3.2e-80 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KCIBCFLH_01919 5.3e-86 yqhR S Conserved membrane protein YqhR
KCIBCFLH_01920 4e-162 yqhQ S Protein of unknown function (DUF1385)
KCIBCFLH_01921 1.3e-10 yqhP
KCIBCFLH_01922 6.9e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
KCIBCFLH_01923 2.1e-166 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KCIBCFLH_01924 4e-175 paaX K PaaX-like protein
KCIBCFLH_01925 2.3e-218 paaJ 2.3.1.16, 2.3.1.174, 2.3.1.223, 2.3.1.9 I Belongs to the thiolase family
KCIBCFLH_01926 5.1e-156 ditN 1.1.1.157, 1.1.1.35, 4.2.1.17, 5.1.2.3, 5.3.3.8 I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
KCIBCFLH_01927 8.5e-287 aldA 1.2.1.3, 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KCIBCFLH_01928 4.4e-90 paaG 5.3.3.18 I Enoyl-CoA hydratase/isomerase
KCIBCFLH_01929 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_01930 1.8e-83 paaF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KCIBCFLH_01931 1.3e-40 ethD S Ethyl tert-butyl ether degradation
KCIBCFLH_01932 8.4e-55 paaD S Phenylacetate-CoA oxygenase
KCIBCFLH_01933 8.3e-92 paaC 1.14.13.149 Q Phenylacetate-CoA oxygenase
KCIBCFLH_01934 7e-34 paaB Q Phenylacetate-CoA oxygenase subunit PaaH
KCIBCFLH_01935 2.6e-151 paaA 1.14.13.149 S With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA
KCIBCFLH_01936 3e-179 paaK 6.2.1.30 H AMP-binding enzyme
KCIBCFLH_01937 3e-21 fdxA C Ferredoxin
KCIBCFLH_01938 7.2e-117 yumC 1.18.1.2, 1.19.1.1 C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase
KCIBCFLH_01939 0.0 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
KCIBCFLH_01940 1e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KCIBCFLH_01941 7.7e-67 yqhL P COG0607 Rhodanese-related sulfurtransferase
KCIBCFLH_01942 6.9e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCIBCFLH_01943 5.1e-201 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCIBCFLH_01944 7.7e-34 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KCIBCFLH_01945 5.8e-216 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KCIBCFLH_01946 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KCIBCFLH_01947 5.3e-155 yqhG S Bacterial protein YqhG of unknown function
KCIBCFLH_01948 6.7e-10 yqzE S YqzE-like protein
KCIBCFLH_01949 2.6e-100 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCIBCFLH_01950 6e-61 S ComG operon protein 7
KCIBCFLH_01951 1.1e-83 comGF U COG4940 Competence protein ComGF
KCIBCFLH_01953 7.2e-77 gspH NU COG2165 Type II secretory pathway, pseudopilin PulG
KCIBCFLH_01954 1.5e-49 comGC U Required for transformation and DNA binding
KCIBCFLH_01955 5.8e-173 comGB NU COG1459 Type II secretory pathway, component PulF
KCIBCFLH_01956 9.5e-178 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCIBCFLH_01957 3.1e-130 K Helix-turn-helix domain
KCIBCFLH_01958 5.7e-36 yqgY S Protein of unknown function (DUF2626)
KCIBCFLH_01959 1e-124 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KCIBCFLH_01960 7.5e-22 yqgW S Protein of unknown function (DUF2759)
KCIBCFLH_01961 8.4e-179 glcK 2.7.1.2 G Glucokinase
KCIBCFLH_01962 3.3e-30 yqgQ S protein conserved in bacteria
KCIBCFLH_01963 1.3e-207 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KCIBCFLH_01965 1.6e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KCIBCFLH_01966 1.2e-53 yqzD
KCIBCFLH_01967 0.0 mrdA 3.4.16.4 M penicillin-binding protein
KCIBCFLH_01968 2e-217 yqgE EGP Major facilitator superfamily
KCIBCFLH_01969 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KCIBCFLH_01970 9.9e-55 fimV NU Tfp pilus assembly protein FimV
KCIBCFLH_01971 7.3e-203 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KCIBCFLH_01972 1.7e-109 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KCIBCFLH_01973 3.8e-75 zur P Belongs to the Fur family
KCIBCFLH_01974 1.8e-140 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KCIBCFLH_01975 6.4e-142 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KCIBCFLH_01976 1.3e-19 yqfT S Protein of unknown function (DUF2624)
KCIBCFLH_01977 4.9e-124 usp CBM50 M protein conserved in bacteria
KCIBCFLH_01978 6.6e-170 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KCIBCFLH_01979 2.7e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KCIBCFLH_01982 5.8e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KCIBCFLH_01983 1.6e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KCIBCFLH_01984 1.2e-112 trmK 2.1.1.217 S SAM-dependent methyltransferase
KCIBCFLH_01985 2.2e-63 cccA C Cytochrome C oxidase, cbb3-type, subunit III
KCIBCFLH_01986 2.1e-86
KCIBCFLH_01987 2e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KCIBCFLH_01988 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KCIBCFLH_01989 1.8e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KCIBCFLH_01990 4.5e-112 ccpN K CBS domain
KCIBCFLH_01991 3.1e-144 recO L Involved in DNA repair and RecF pathway recombination
KCIBCFLH_01992 3e-08 S YqzL-like protein
KCIBCFLH_01993 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCIBCFLH_01994 3e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KCIBCFLH_01995 9.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KCIBCFLH_01996 0.0 yqfF S membrane-associated HD superfamily hydrolase
KCIBCFLH_01997 5.2e-173 phoH T Phosphate starvation-inducible protein PhoH
KCIBCFLH_01998 2e-227 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KCIBCFLH_01999 4.2e-46 yqfC S sporulation protein YqfC
KCIBCFLH_02000 5.4e-72 yqeY S Yqey-like protein
KCIBCFLH_02001 9.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KCIBCFLH_02002 8.5e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KCIBCFLH_02003 3.3e-156 yqeW P COG1283 Na phosphate symporter
KCIBCFLH_02004 5.5e-261 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KCIBCFLH_02005 1.6e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KCIBCFLH_02006 1.7e-173 prmA J Methylates ribosomal protein L11
KCIBCFLH_02007 1.5e-206 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KCIBCFLH_02008 2.5e-309 dnaK O Heat shock 70 kDa protein
KCIBCFLH_02009 1.9e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCIBCFLH_02010 3.2e-189 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KCIBCFLH_02011 2.5e-219 hemN H Involved in the biosynthesis of porphyrin-containing compound
KCIBCFLH_02012 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KCIBCFLH_02013 1.6e-224 spoIIP M stage II sporulation protein P
KCIBCFLH_02014 1.1e-198 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KCIBCFLH_02015 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
KCIBCFLH_02016 1.4e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
KCIBCFLH_02017 3.1e-07 S YqzM-like protein
KCIBCFLH_02018 1.5e-140 comEC S Competence protein ComEC
KCIBCFLH_02019 3e-284 comEC S Competence protein ComEC
KCIBCFLH_02020 6.5e-113 comEB 3.5.4.12 F COG2131 Deoxycytidylate deaminase
KCIBCFLH_02021 4e-85 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KCIBCFLH_02022 1.1e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCIBCFLH_02023 8.5e-147 cmoA S Methyltransferase domain
KCIBCFLH_02024 2.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KCIBCFLH_02025 1.6e-100 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KCIBCFLH_02026 1.9e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCIBCFLH_02027 8.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KCIBCFLH_02028 3.1e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCIBCFLH_02029 7e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KCIBCFLH_02030 2.6e-94 yqeG S hydrolase of the HAD superfamily
KCIBCFLH_02031 1.5e-258 glcF C Glycolate oxidase
KCIBCFLH_02032 5.5e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
KCIBCFLH_02033 6.7e-193 ysfB KT regulator
KCIBCFLH_02034 1.9e-280 mco 1.16.3.3 Q multicopper oxidases
KCIBCFLH_02035 1.8e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
KCIBCFLH_02036 7.8e-67 perX S DsrE/DsrF-like family
KCIBCFLH_02037 5.3e-39 O Glutaredoxin
KCIBCFLH_02038 8.2e-55 P Rhodanese Homology Domain
KCIBCFLH_02039 0.0 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KCIBCFLH_02040 2.5e-18 S Short C-terminal domain
KCIBCFLH_02041 4.2e-236 mco 1.16.3.3 Q multicopper oxidases
KCIBCFLH_02042 3.9e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
KCIBCFLH_02043 5.4e-23 S Short C-terminal domain
KCIBCFLH_02044 1.6e-266 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_02045 2.9e-107 CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KCIBCFLH_02046 8.2e-116 S TPM domain
KCIBCFLH_02047 4.7e-76 lemA S LemA family
KCIBCFLH_02048 4.3e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KCIBCFLH_02049 8.8e-61 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KCIBCFLH_02050 9.1e-119 S VIT family
KCIBCFLH_02051 1.7e-152 czcD P COG1230 Co Zn Cd efflux system component
KCIBCFLH_02052 4.2e-15 sda S Sporulation inhibitor A
KCIBCFLH_02053 1.3e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCIBCFLH_02054 2.1e-126 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCIBCFLH_02055 9.9e-291 ahpF O Alkyl hydroperoxide reductase
KCIBCFLH_02056 3.8e-107 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KCIBCFLH_02058 5e-10 S YrhC-like protein
KCIBCFLH_02059 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCIBCFLH_02060 1.2e-29 yrzA S Protein of unknown function (DUF2536)
KCIBCFLH_02061 5.5e-59 yrrS S Protein of unknown function (DUF1510)
KCIBCFLH_02062 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KCIBCFLH_02063 6.8e-113 udk 2.7.1.48 F Cytidine monophosphokinase
KCIBCFLH_02064 1.1e-115 yrrM 2.1.1.104 S O-methyltransferase
KCIBCFLH_02065 5.9e-205 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCIBCFLH_02066 1.5e-41 yrzB S Belongs to the UPF0473 family
KCIBCFLH_02067 8.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCIBCFLH_02068 5.8e-45 yrzL S Belongs to the UPF0297 family
KCIBCFLH_02069 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KCIBCFLH_02070 8.2e-175 yrrI S AI-2E family transporter
KCIBCFLH_02072 1.8e-29 yrzR
KCIBCFLH_02073 1.8e-67 yndM S Protein of unknown function (DUF2512)
KCIBCFLH_02074 4.5e-58 K helix_turn_helix ASNC type
KCIBCFLH_02076 4.3e-61 pdh 1.4.1.20, 1.4.1.9 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
KCIBCFLH_02078 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KCIBCFLH_02079 7.4e-126 S COG0457 FOG TPR repeat
KCIBCFLH_02080 3.4e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KCIBCFLH_02081 1.5e-211 iscS 2.8.1.7 E Cysteine desulfurase
KCIBCFLH_02082 2.3e-72 cymR K Transcriptional regulator
KCIBCFLH_02083 1.5e-26
KCIBCFLH_02084 6.7e-136 IQ Short-chain dehydrogenase reductase sdr
KCIBCFLH_02085 3e-237 cshA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KCIBCFLH_02086 3.1e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KCIBCFLH_02087 5.5e-162 ybaS 1.1.1.58 S Na -dependent transporter
KCIBCFLH_02089 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KCIBCFLH_02090 1.7e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
KCIBCFLH_02092 6.3e-271 lytH 3.5.1.28, 6.1.1.12 M COG3103 SH3 domain protein
KCIBCFLH_02093 0.0 yhcA5 EGP Major facilitator Superfamily
KCIBCFLH_02094 1.2e-107 emrA V Barrel-sandwich domain of CusB or HlyD membrane-fusion
KCIBCFLH_02095 1.7e-70 K helix_turn_helix multiple antibiotic resistance protein
KCIBCFLH_02096 1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KCIBCFLH_02097 1.7e-298 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCIBCFLH_02098 4.4e-82 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCIBCFLH_02099 9e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCIBCFLH_02100 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KCIBCFLH_02101 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KCIBCFLH_02102 1.2e-54 yrzD S Post-transcriptional regulator
KCIBCFLH_02103 4.5e-275 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KCIBCFLH_02104 9.5e-110 yrbG S membrane
KCIBCFLH_02105 1.4e-63 yrzE S Protein of unknown function (DUF3792)
KCIBCFLH_02106 8.7e-51 yajC U Preprotein translocase subunit YajC
KCIBCFLH_02107 5.3e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KCIBCFLH_02108 9.8e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCIBCFLH_02109 3.2e-27 yrzS S Protein of unknown function (DUF2905)
KCIBCFLH_02110 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KCIBCFLH_02111 1.3e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KCIBCFLH_02112 3.8e-128 yebC K transcriptional regulatory protein
KCIBCFLH_02113 1.4e-189 1.1.1.34, 2.7.1.89 M choline kinase involved in LPS biosynthesis
KCIBCFLH_02114 2.9e-131 safA M spore coat assembly protein SafA
KCIBCFLH_02115 3.9e-96 niaR S small molecule binding protein (contains 3H domain)
KCIBCFLH_02116 1.1e-158 pheA 4.2.1.51 E Prephenate dehydratase
KCIBCFLH_02117 1.2e-74 pheB 5.4.99.5 S Belongs to the UPF0735 family
KCIBCFLH_02118 1.3e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCIBCFLH_02119 7e-95 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KCIBCFLH_02120 1.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KCIBCFLH_02121 3.5e-52 ysxB J ribosomal protein
KCIBCFLH_02122 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
KCIBCFLH_02123 2.9e-279 rng J ribonuclease, Rne Rng family
KCIBCFLH_02124 9.8e-163 spoIVFB S Stage IV sporulation protein
KCIBCFLH_02125 3e-136 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KCIBCFLH_02126 1e-145 minD D Belongs to the ParA family
KCIBCFLH_02127 2.3e-122 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KCIBCFLH_02128 2.8e-88 mreD M shape-determining protein
KCIBCFLH_02129 4.4e-139 mreC M Involved in formation and maintenance of cell shape
KCIBCFLH_02130 6.9e-184 mreB D Rod shape-determining protein MreB
KCIBCFLH_02131 2.4e-119 radC E Belongs to the UPF0758 family
KCIBCFLH_02132 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_02134 3.6e-169 spoIIB
KCIBCFLH_02135 3.1e-128 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KCIBCFLH_02136 7.3e-100
KCIBCFLH_02137 5.6e-81 pilN NU PFAM Fimbrial assembly family protein
KCIBCFLH_02138 4.9e-190 NU COG4972 Tfp pilus assembly protein, ATPase PilM
KCIBCFLH_02139 1.4e-45 NU cell adhesion
KCIBCFLH_02140 6.7e-202 pilC NU type II secretion system
KCIBCFLH_02141 1.5e-194 pilT NU twitching motility protein
KCIBCFLH_02142 7.9e-294 pilB NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCIBCFLH_02143 1.8e-222 V G5
KCIBCFLH_02144 1.5e-127 S PRC-barrel domain
KCIBCFLH_02145 2.3e-211
KCIBCFLH_02146 8.3e-235 NU Pilus assembly protein PilX
KCIBCFLH_02147 6.7e-87
KCIBCFLH_02149 1.1e-253 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KCIBCFLH_02150 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KCIBCFLH_02151 9.5e-26
KCIBCFLH_02152 1.6e-227 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KCIBCFLH_02153 6.8e-198 spoVID M stage VI sporulation protein D
KCIBCFLH_02154 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KCIBCFLH_02155 7.1e-186 hemB 4.2.1.24 H Belongs to the ALAD family
KCIBCFLH_02156 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KCIBCFLH_02157 4.9e-168 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KCIBCFLH_02158 7.7e-149 hemX O cytochrome C
KCIBCFLH_02159 1.2e-241 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KCIBCFLH_02160 4.5e-88 ysxD
KCIBCFLH_02161 4.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KCIBCFLH_02162 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KCIBCFLH_02163 1e-309 lonB 3.4.21.53 LO Belongs to the peptidase S16 family
KCIBCFLH_02164 1.7e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCIBCFLH_02165 4.3e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KCIBCFLH_02166 1.6e-185 S chaperone-mediated protein folding
KCIBCFLH_02167 1.4e-72 S Protein of unknown function (DUF2512)
KCIBCFLH_02168 1.2e-46
KCIBCFLH_02169 2.2e-08
KCIBCFLH_02171 2.8e-93 ysnB S Phosphoesterase
KCIBCFLH_02172 1.6e-106 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCIBCFLH_02173 7.8e-191 gerM S COG5401 Spore germination protein
KCIBCFLH_02174 4.3e-13
KCIBCFLH_02175 2.6e-46 M Spore coat protein
KCIBCFLH_02176 6.1e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KCIBCFLH_02177 6e-61 yraF M Spore coat protein
KCIBCFLH_02178 1.3e-31 yraG S Spore Coat Protein
KCIBCFLH_02179 5.8e-149 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KCIBCFLH_02180 2.7e-79 ysmB 2.4.2.28 K transcriptional
KCIBCFLH_02181 1.4e-92 S GDYXXLXY protein
KCIBCFLH_02182 2.5e-195 S Predicted membrane protein (DUF2157)
KCIBCFLH_02184 2.3e-31 gerE K Transcriptional regulator
KCIBCFLH_02185 6.7e-89 ysmA S thioesterase
KCIBCFLH_02186 1.3e-150 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KCIBCFLH_02187 1.2e-298 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KCIBCFLH_02188 1.2e-23 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KCIBCFLH_02189 2.5e-104 sdhC C succinate dehydrogenase
KCIBCFLH_02190 1.7e-81 yslB S Protein of unknown function (DUF2507)
KCIBCFLH_02191 5.6e-220 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KCIBCFLH_02192 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KCIBCFLH_02193 6.7e-53 trxA O Belongs to the thioredoxin family
KCIBCFLH_02194 1.1e-173 etfA C Electron transfer flavoprotein
KCIBCFLH_02195 1.6e-127 etfB C Electron transfer flavoprotein
KCIBCFLH_02196 3e-139 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KCIBCFLH_02197 1.6e-103 fadR K Transcriptional regulator
KCIBCFLH_02198 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KCIBCFLH_02199 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KCIBCFLH_02200 0.0 polX L COG1796 DNA polymerase IV (family X)
KCIBCFLH_02201 4.9e-88 cvpA S membrane protein, required for colicin V production
KCIBCFLH_02202 7.3e-46 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KCIBCFLH_02203 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCIBCFLH_02204 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCIBCFLH_02205 3.2e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCIBCFLH_02208 5e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCIBCFLH_02209 2.2e-31 sspI S Belongs to the SspI family
KCIBCFLH_02210 2.4e-77
KCIBCFLH_02211 7.9e-260 L Transposase
KCIBCFLH_02212 1.3e-232 L COG3547 Transposase and inactivated derivatives
KCIBCFLH_02213 2.9e-141 S Domain of unknown function (DUF4405)
KCIBCFLH_02214 1.4e-41
KCIBCFLH_02215 6.3e-57 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KCIBCFLH_02216 7.1e-199 L COG3039 Transposase and inactivated derivatives, IS5 family
KCIBCFLH_02217 6.1e-123 M1-1017 S Protein of unknown function (DUF1129)
KCIBCFLH_02218 1.8e-56 K Transcriptional regulator
KCIBCFLH_02219 2.3e-11 S NADPH-dependent FMN reductase
KCIBCFLH_02220 6.7e-127 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KCIBCFLH_02221 6.8e-178 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCIBCFLH_02222 4.7e-102 yieF S NAD(P)H-dependent FMN reductase
KCIBCFLH_02223 3.4e-122 mcpB3 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KCIBCFLH_02224 1.2e-180 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KCIBCFLH_02225 2.5e-94 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KCIBCFLH_02226 1.1e-259 M O-Antigen ligase
KCIBCFLH_02227 7.3e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KCIBCFLH_02229 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCIBCFLH_02230 3.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KCIBCFLH_02231 4.5e-112 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCIBCFLH_02232 2.3e-224 G Transmembrane secretion effector
KCIBCFLH_02233 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCIBCFLH_02234 2.3e-153 ytxC S YtxC-like family
KCIBCFLH_02235 2.1e-179 dnaI L Primosomal protein DnaI
KCIBCFLH_02236 7.4e-261 dnaB L Membrane attachment protein
KCIBCFLH_02237 2.1e-79 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCIBCFLH_02238 1.4e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KCIBCFLH_02239 1.3e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KCIBCFLH_02240 1.6e-109 ytaF P Probably functions as a manganese efflux pump
KCIBCFLH_02241 6.5e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KCIBCFLH_02242 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCIBCFLH_02243 2.6e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KCIBCFLH_02244 4e-245 icd 1.1.1.42 C isocitrate
KCIBCFLH_02245 1.5e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
KCIBCFLH_02246 1e-73 yeaL S Membrane
KCIBCFLH_02247 1.3e-159 ytvI S sporulation integral membrane protein YtvI
KCIBCFLH_02248 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KCIBCFLH_02249 3e-176 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KCIBCFLH_02250 1.1e-178 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KCIBCFLH_02251 4e-164 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCIBCFLH_02252 2.8e-227 ytsJ 1.1.1.38 C Malate dehydrogenase
KCIBCFLH_02253 0.0 dnaE 2.7.7.7 L DNA polymerase
KCIBCFLH_02254 5e-14 ytrH S Sporulation protein YtrH
KCIBCFLH_02255 4.2e-89 ytrI
KCIBCFLH_02256 5.2e-178 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KCIBCFLH_02257 1.8e-42 ytpI S YtpI-like protein
KCIBCFLH_02258 1.5e-239 ytoI K transcriptional regulator containing CBS domains
KCIBCFLH_02259 1.5e-129 ytkL S Belongs to the UPF0173 family
KCIBCFLH_02260 6.9e-136 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KCIBCFLH_02261 2.2e-44 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KCIBCFLH_02262 6.2e-202 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KCIBCFLH_02263 5.6e-80 uspA T Belongs to the universal stress protein A family
KCIBCFLH_02264 5e-156 S EcsC protein family
KCIBCFLH_02265 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCIBCFLH_02266 2.2e-182 ytxK 2.1.1.72 L DNA methylase
KCIBCFLH_02267 5.8e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KCIBCFLH_02268 5.8e-69 ytfJ S Sporulation protein YtfJ
KCIBCFLH_02269 4.8e-117 ytfI S Protein of unknown function (DUF2953)
KCIBCFLH_02270 3.3e-89 yteJ S RDD family
KCIBCFLH_02271 1.4e-184 sppA OU signal peptide peptidase SppA
KCIBCFLH_02272 8.2e-309 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KCIBCFLH_02273 1.4e-27 sspB S spore protein
KCIBCFLH_02274 5.6e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCIBCFLH_02275 6.8e-212 iscS2 2.8.1.7 E Cysteine desulfurase
KCIBCFLH_02276 1.7e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KCIBCFLH_02277 4.6e-117 yttP K Transcriptional regulator
KCIBCFLH_02278 1.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
KCIBCFLH_02279 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KCIBCFLH_02280 1.9e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KCIBCFLH_02281 5.7e-146
KCIBCFLH_02282 4e-72 K Helix-turn-helix XRE-family like proteins
KCIBCFLH_02283 4.4e-183 putA E Proline dehydrogenase
KCIBCFLH_02284 7.8e-296 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KCIBCFLH_02285 1.2e-244 prdR KT Transcriptional regulator
KCIBCFLH_02286 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCIBCFLH_02287 3.3e-152 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KCIBCFLH_02288 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_02289 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KCIBCFLH_02290 4.8e-88 yrhD S Protein of unknown function (DUF1641)
KCIBCFLH_02291 8e-193 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KCIBCFLH_02292 5.1e-84 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KCIBCFLH_02293 3e-34 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KCIBCFLH_02294 3.9e-78 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KCIBCFLH_02295 3.4e-88 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KCIBCFLH_02296 7.1e-239 moeA 2.10.1.1 H molybdopterin
KCIBCFLH_02297 1.9e-121 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KCIBCFLH_02298 8.1e-85 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KCIBCFLH_02299 5.4e-189 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KCIBCFLH_02300 4.1e-130 modC 3.6.3.29 P ATPases associated with a variety of cellular activities
KCIBCFLH_02301 1.1e-101 P COG4149 ABC-type molybdate transport system, permease component
KCIBCFLH_02302 1.2e-122 modA P Molybdenum ABC transporter
KCIBCFLH_02303 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KCIBCFLH_02304 1e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KCIBCFLH_02305 1.1e-118 acuB S Acetoin utilization protein AcuB
KCIBCFLH_02306 5.4e-233 acuC BQ histone deacetylase
KCIBCFLH_02307 1.3e-182 ccpA K catabolite control protein A
KCIBCFLH_02308 3.8e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KCIBCFLH_02309 4.2e-33 XK27_07760 S COG4980 Gas vesicle protein
KCIBCFLH_02310 5.6e-52 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KCIBCFLH_02311 3e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KCIBCFLH_02312 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KCIBCFLH_02313 8.8e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KCIBCFLH_02314 4.4e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCIBCFLH_02315 3.4e-146 ytpQ S Belongs to the UPF0354 family
KCIBCFLH_02316 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KCIBCFLH_02317 8e-205 rsbU 3.1.3.3 T response regulator
KCIBCFLH_02318 7.3e-155 cheR 2.1.1.80 NT chemotaxis
KCIBCFLH_02319 0.0 T PhoQ Sensor
KCIBCFLH_02320 2.2e-192 EGP Transmembrane secretion effector
KCIBCFLH_02322 3.8e-33
KCIBCFLH_02323 4.2e-92 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KCIBCFLH_02324 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KCIBCFLH_02325 3.3e-52 ytzB S small secreted protein
KCIBCFLH_02326 1.4e-171 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KCIBCFLH_02327 7.6e-134 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KCIBCFLH_02328 8.8e-59 ytzH S YtzH-like protein
KCIBCFLH_02329 2.8e-156 ytmP 2.7.1.89 M Phosphotransferase
KCIBCFLH_02330 4e-149 ytlQ
KCIBCFLH_02331 6.6e-107 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KCIBCFLH_02333 2.3e-159 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KCIBCFLH_02334 3.5e-274 pepV 3.5.1.18 E Dipeptidase
KCIBCFLH_02335 1.2e-32 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KCIBCFLH_02336 7e-287 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KCIBCFLH_02337 4.1e-26 yteV S Sporulation protein Cse60
KCIBCFLH_02338 1.7e-10
KCIBCFLH_02340 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCIBCFLH_02341 7.3e-185 yttB EGP Major facilitator Superfamily
KCIBCFLH_02342 1.6e-42 ytzC S Protein of unknown function (DUF2524)
KCIBCFLH_02343 5.2e-104 ytqB J Putative rRNA methylase
KCIBCFLH_02345 1e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KCIBCFLH_02346 2e-154 ytpA 3.1.1.5 I Alpha beta hydrolase
KCIBCFLH_02347 2.5e-73 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KCIBCFLH_02348 0.0 asnB 6.3.5.4 E Asparagine synthase
KCIBCFLH_02349 5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCIBCFLH_02350 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KCIBCFLH_02351 4.8e-69 3.6.1.13, 3.6.1.55 L NTP pyrophosphohydrolases including oxidative damage repair enzymes
KCIBCFLH_02352 1.9e-208 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KCIBCFLH_02353 1.3e-101 ywqN S NAD(P)H-dependent
KCIBCFLH_02354 1.9e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KCIBCFLH_02355 8e-126 tnp4 L Transposase, Mutator family
KCIBCFLH_02356 3.7e-268 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_02357 7.7e-42 tnp4 L Transposase, Mutator family
KCIBCFLH_02358 2.3e-38 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KCIBCFLH_02359 4.6e-97 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KCIBCFLH_02360 6.1e-140 ytlC P ABC transporter
KCIBCFLH_02361 1.6e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KCIBCFLH_02362 4.9e-84 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KCIBCFLH_02363 7.4e-39
KCIBCFLH_02364 5.6e-77 dps P Belongs to the Dps family
KCIBCFLH_02365 1.3e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KCIBCFLH_02367 6.3e-165 adcA P Belongs to the bacterial solute-binding protein 9 family
KCIBCFLH_02368 1.6e-23 S Domain of Unknown Function (DUF1540)
KCIBCFLH_02369 3.4e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KCIBCFLH_02370 2.3e-107 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KCIBCFLH_02371 1.3e-143 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KCIBCFLH_02372 7.1e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KCIBCFLH_02373 4.8e-148 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KCIBCFLH_02374 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KCIBCFLH_02375 7.7e-255 menF 5.4.4.2 HQ Isochorismate synthase
KCIBCFLH_02376 3.8e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KCIBCFLH_02386 3e-09
KCIBCFLH_02392 5.1e-08
KCIBCFLH_02393 1.6e-08
KCIBCFLH_02397 7.6e-39 S COG NOG15344 non supervised orthologous group
KCIBCFLH_02398 1.7e-41
KCIBCFLH_02399 4.3e-42 S COG NOG14552 non supervised orthologous group
KCIBCFLH_02400 6e-232 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
KCIBCFLH_02402 1.2e-56 V ATPases associated with a variety of cellular activities
KCIBCFLH_02403 8.5e-70 S Protein of unknown function (DUF1430)
KCIBCFLH_02404 4.4e-17
KCIBCFLH_02405 9e-151 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KCIBCFLH_02406 5.5e-116 sapB S MgtC SapB transporter
KCIBCFLH_02407 4.4e-165 S Protein of unknown function (DUF1646)
KCIBCFLH_02408 7e-60 EGP Major facilitator Superfamily
KCIBCFLH_02409 0.0 copA 3.6.3.54 P P-type ATPase
KCIBCFLH_02410 8.9e-30 P Copper resistance protein CopZ
KCIBCFLH_02411 8.4e-57 S protein conserved in bacteria
KCIBCFLH_02412 2.4e-243 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_02413 5.8e-82 L PFAM Transposase, IS4-like
KCIBCFLH_02414 3.8e-70 K Helix-turn-helix domain
KCIBCFLH_02415 9.9e-260 L PFAM Transposase, IS4-like
KCIBCFLH_02416 7.9e-30 csoR_2 S Metal-sensitive transcriptional repressor
KCIBCFLH_02417 4.3e-68 lrpC K Transcriptional regulator
KCIBCFLH_02418 1.2e-68 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KCIBCFLH_02419 4e-223 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KCIBCFLH_02420 1.3e-27 yhjC S Protein of unknown function (DUF3311)
KCIBCFLH_02421 1.4e-265 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCIBCFLH_02424 3.1e-33 S Protein of unknown function (DUF2933)
KCIBCFLH_02426 8.5e-249 T PhoQ Sensor
KCIBCFLH_02427 1.5e-126 KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCIBCFLH_02428 4.9e-91 ydhK M Protein of unknown function (DUF1541)
KCIBCFLH_02429 1.7e-99 VY92_08700 S Enoyl-(Acyl carrier protein) reductase
KCIBCFLH_02430 1.3e-10 recN L Putative cell-wall binding lipoprotein
KCIBCFLH_02431 4.1e-175 nodB1 G deacetylase
KCIBCFLH_02435 5.2e-90 P Voltage gated chloride channel
KCIBCFLH_02436 4.2e-142 P Voltage gated chloride channel
KCIBCFLH_02437 1.9e-49 P Rhodanese domain protein
KCIBCFLH_02438 7.6e-16
KCIBCFLH_02439 2.9e-129 yokF 3.1.31.1 L RNA catabolic process
KCIBCFLH_02440 7.3e-71 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
KCIBCFLH_02441 1.8e-262 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_02442 3.5e-307 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KCIBCFLH_02443 1.8e-254 araP EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KCIBCFLH_02444 2.7e-131 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KCIBCFLH_02445 3.5e-282 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KCIBCFLH_02446 6.1e-213 araR K transcriptional
KCIBCFLH_02447 4.2e-37 chvE G ABC transporter
KCIBCFLH_02448 3e-248 L PFAM Transposase, IS4-like
KCIBCFLH_02449 1.4e-150 chvE G ABC transporter
KCIBCFLH_02450 1e-284 araG 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KCIBCFLH_02451 3.5e-181 gguB G Belongs to the binding-protein-dependent transport system permease family
KCIBCFLH_02452 4.8e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KCIBCFLH_02453 0.0 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KCIBCFLH_02454 2.7e-241 araR K transcriptional
KCIBCFLH_02455 1.8e-215 NT chemotaxis protein
KCIBCFLH_02456 5.3e-127 plsB 2.3.1.15 I Acyl-transferase
KCIBCFLH_02457 2.3e-201 2.4.1.83 GT2 M Glycosyl transferase family 2
KCIBCFLH_02458 3.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
KCIBCFLH_02459 6e-74 yuiD S protein conserved in bacteria
KCIBCFLH_02460 1.9e-214 solA 1.5.3.1 E FAD dependent oxidoreductase
KCIBCFLH_02461 1.3e-218 FOXRED 1.5.3.1 E FAD dependent oxidoreductase
KCIBCFLH_02462 1.2e-280 ycbD 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KCIBCFLH_02463 6.2e-171 4.3.1.12 E ornithine cyclodeaminase
KCIBCFLH_02466 1.9e-181 yugO P COG1226 Kef-type K transport systems
KCIBCFLH_02467 7.9e-260 pgi 5.3.1.9 G Belongs to the GPI family
KCIBCFLH_02468 6.7e-34 yuzA S Domain of unknown function (DUF378)
KCIBCFLH_02469 1.5e-85 K Bacterial transcription activator, effector binding domain
KCIBCFLH_02471 7.2e-65 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KCIBCFLH_02472 1e-28 K Helix-turn-helix XRE-family like proteins
KCIBCFLH_02473 5.2e-195 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KCIBCFLH_02474 1.6e-165 S reductase
KCIBCFLH_02475 4.9e-159 dkgB S Aldo/keto reductase family
KCIBCFLH_02476 2.4e-239 S protein conserved in bacteria
KCIBCFLH_02478 2.3e-110 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCIBCFLH_02479 9.9e-67 kapB G Kinase associated protein B
KCIBCFLH_02480 2.1e-12 S transposase or invertase
KCIBCFLH_02481 1.3e-11 S transposase or invertase
KCIBCFLH_02482 8.8e-140 S transposase or invertase
KCIBCFLH_02483 9.1e-191 yuxJ EGP Major facilitator Superfamily
KCIBCFLH_02484 9.4e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
KCIBCFLH_02485 5.3e-62 yuzC
KCIBCFLH_02487 1.5e-184 E Spore germination protein
KCIBCFLH_02488 1.1e-220 gerKC S spore germination
KCIBCFLH_02489 7.6e-281 gerKA EG Spore germination protein
KCIBCFLH_02491 6e-304 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KCIBCFLH_02492 6.4e-108 yuiC S protein conserved in bacteria
KCIBCFLH_02493 1.2e-46 yuiB S Putative membrane protein
KCIBCFLH_02494 2.4e-231 yumB 1.6.99.3 C NADH dehydrogenase
KCIBCFLH_02495 3.3e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
KCIBCFLH_02496 6.3e-89 S response to antibiotic
KCIBCFLH_02497 7.7e-48 tcaA S response to antibiotic
KCIBCFLH_02498 2.9e-64 ycdA S Domain of unknown function (DUF4352)
KCIBCFLH_02499 2.2e-63 erpA S Belongs to the HesB IscA family
KCIBCFLH_02500 1.1e-59 yuzD S protein conserved in bacteria
KCIBCFLH_02501 8.6e-37 nifU O COG0694 Thioredoxin-like proteins and domains
KCIBCFLH_02502 9e-200 yutH S Spore coat protein
KCIBCFLH_02503 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KCIBCFLH_02504 3.3e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KCIBCFLH_02505 1.9e-74 yutE S Protein of unknown function DUF86
KCIBCFLH_02506 1.5e-48 yutD S protein conserved in bacteria
KCIBCFLH_02507 1e-173 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KCIBCFLH_02508 1.2e-196 lytH M Peptidase, M23
KCIBCFLH_02509 1.7e-120 yunB S Sporulation protein YunB (Spo_YunB)
KCIBCFLH_02510 8.2e-48 yunC S Domain of unknown function (DUF1805)
KCIBCFLH_02511 5.1e-286 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KCIBCFLH_02512 2.9e-273 sufB O FeS cluster assembly
KCIBCFLH_02513 6.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KCIBCFLH_02514 9.1e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCIBCFLH_02515 1.4e-242 sufD O assembly protein SufD
KCIBCFLH_02516 2.7e-143 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KCIBCFLH_02518 1.6e-51 traF CO Thioredoxin
KCIBCFLH_02519 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KCIBCFLH_02520 1.3e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KCIBCFLH_02521 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KCIBCFLH_02522 6.1e-216 fadA 2.3.1.16 I Belongs to the thiolase family
KCIBCFLH_02523 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KCIBCFLH_02524 2.6e-14 S YuzL-like protein
KCIBCFLH_02525 7.4e-42
KCIBCFLH_02526 1.6e-55 yusN M Coat F domain
KCIBCFLH_02527 8.1e-205 rodA D Belongs to the SEDS family
KCIBCFLH_02528 3.3e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KCIBCFLH_02529 5.1e-281 cls2 I PLD-like domain
KCIBCFLH_02531 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KCIBCFLH_02533 1.1e-198 L COG3039 Transposase and inactivated derivatives, IS5 family
KCIBCFLH_02534 4.1e-192 M1-600 T Putative diguanylate phosphodiesterase
KCIBCFLH_02535 1.7e-300 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KCIBCFLH_02536 1.6e-105 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KCIBCFLH_02537 1.3e-142 pgdA 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
KCIBCFLH_02538 5.2e-245 ugtP 2.4.1.315 GT28 M Monogalactosyldiacylglycerol (MGDG) synthase
KCIBCFLH_02539 1.5e-131
KCIBCFLH_02540 1.9e-86 S Putative zinc-finger
KCIBCFLH_02541 5e-93 K Belongs to the sigma-70 factor family. ECF subfamily
KCIBCFLH_02542 4.6e-224 ykoN 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KCIBCFLH_02543 0.0 M Dolichyl-phosphate-mannose-protein mannosyltransferase
KCIBCFLH_02544 1.6e-258 NU cell adhesion
KCIBCFLH_02545 1.3e-182 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KCIBCFLH_02546 1.1e-178 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KCIBCFLH_02547 4.9e-167 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KCIBCFLH_02548 3.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCIBCFLH_02549 1.7e-260 yjmB G MFS/sugar transport protein
KCIBCFLH_02550 1.8e-286 uxaC 5.3.1.12 G glucuronate isomerase
KCIBCFLH_02551 9.9e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KCIBCFLH_02552 1.4e-278 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KCIBCFLH_02553 1.4e-192 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
KCIBCFLH_02554 1.6e-120 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KCIBCFLH_02555 1.3e-137 K helix_turn_helix isocitrate lyase regulation
KCIBCFLH_02556 1.4e-198 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_02557 1.1e-55 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_02559 6e-219 O Peptidase S53
KCIBCFLH_02560 5.2e-36 S Transcriptional Coactivator p15 (PC4)
KCIBCFLH_02562 2.4e-27 sidE D nuclear chromosome segregation
KCIBCFLH_02563 1.2e-99
KCIBCFLH_02564 5.5e-100
KCIBCFLH_02565 1.2e-150 S transposase or invertase
KCIBCFLH_02567 1.5e-80 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KCIBCFLH_02568 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KCIBCFLH_02569 4.8e-142 est 3.1.1.1 S Carboxylesterase
KCIBCFLH_02570 2.5e-28 secG U Preprotein translocase subunit SecG
KCIBCFLH_02571 1.6e-241 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KCIBCFLH_02572 1.9e-302 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KCIBCFLH_02573 6.9e-120 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KCIBCFLH_02574 2.2e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KCIBCFLH_02575 9.6e-186 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KCIBCFLH_02576 1.5e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KCIBCFLH_02577 8.7e-40 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KCIBCFLH_02578 1.2e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KCIBCFLH_02580 2.6e-07 S Heavy-metal-associated domain
KCIBCFLH_02581 2.6e-57 S Protein of unknown function (DUF1641)
KCIBCFLH_02583 3.4e-49 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KCIBCFLH_02584 3e-102 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KCIBCFLH_02585 5.6e-49 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KCIBCFLH_02586 5.8e-137 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KCIBCFLH_02587 4.9e-23 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KCIBCFLH_02589 5.4e-20 S transposase or invertase
KCIBCFLH_02590 2e-158 S transposase or invertase
KCIBCFLH_02591 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCIBCFLH_02592 4.3e-86 uspF T Universal stress protein
KCIBCFLH_02594 2.6e-191 ykfD E Belongs to the ABC transporter superfamily
KCIBCFLH_02595 3.9e-178 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KCIBCFLH_02596 0.0 dppE E ABC transporter substrate-binding protein
KCIBCFLH_02597 6.4e-190 dppD P Belongs to the ABC transporter superfamily
KCIBCFLH_02598 1.4e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCIBCFLH_02599 1.3e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCIBCFLH_02600 6.2e-131 S Peptidase C26
KCIBCFLH_02601 1.3e-184 corA P Mediates influx of magnesium ions
KCIBCFLH_02602 3.9e-46 yhdB S YhdB-like protein
KCIBCFLH_02604 3.5e-279 ycgB S Stage V sporulation protein R
KCIBCFLH_02605 3.2e-186 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KCIBCFLH_02606 3.7e-136 3.2.1.18 GH33 E GDSL-like Lipase/Acylhydrolase
KCIBCFLH_02607 3.1e-77 bdbC O Required for disulfide bond formation in some proteins
KCIBCFLH_02608 2.9e-87 bdbA CO Thioredoxin
KCIBCFLH_02609 4.9e-90 yhcU S Family of unknown function (DUF5365)
KCIBCFLH_02610 3.3e-112 ykaA P Protein of unknown function DUF47
KCIBCFLH_02611 5.6e-178 pit P phosphate transporter
KCIBCFLH_02612 1.1e-103 2.3.1.128 J Acetyltransferase (GNAT) domain
KCIBCFLH_02614 9.6e-222 yhbH S Belongs to the UPF0229 family
KCIBCFLH_02615 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_02616 0.0 prkA T Ser protein kinase
KCIBCFLH_02617 2.6e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KCIBCFLH_02618 1.9e-166 yhbB S Putative amidase domain
KCIBCFLH_02619 1.2e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCIBCFLH_02620 1.3e-103 yvbG U UPF0056 membrane protein
KCIBCFLH_02621 6.6e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KCIBCFLH_02622 1.7e-84 S Rubrerythrin
KCIBCFLH_02623 1.4e-166 pip 3.4.11.5, 3.5.1.101 S Releases the N-terminal proline from various substrates
KCIBCFLH_02624 2.9e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KCIBCFLH_02625 1.9e-116 tcyB P COG0765 ABC-type amino acid transport system, permease component
KCIBCFLH_02626 5.3e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KCIBCFLH_02627 1.6e-149 focA P Formate/nitrite transporter
KCIBCFLH_02628 1.7e-215 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
KCIBCFLH_02629 0.0 pflB 2.3.1.54 C formate acetyltransferase
KCIBCFLH_02630 1.7e-144 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCIBCFLH_02631 5.8e-100 1.5.1.38 S FMN reductase
KCIBCFLH_02632 1.4e-90
KCIBCFLH_02633 4.8e-174 bcrB S ABC transporter (permease)
KCIBCFLH_02634 1.1e-169 bcrA V ABC transporter, ATP-binding protein
KCIBCFLH_02635 6.8e-142 ypmR1 E G-D-S-L family
KCIBCFLH_02636 6.2e-32
KCIBCFLH_02637 0.0 L Domain of unknown function (DUF4277)
KCIBCFLH_02639 9.7e-145 S High confidence in function and specificity
KCIBCFLH_02640 9.8e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCIBCFLH_02641 2.3e-220 ykoH3 T Histidine kinase
KCIBCFLH_02642 6e-109
KCIBCFLH_02643 1.7e-64 folT 2.7.13.3 T ECF transporter, substrate-specific component
KCIBCFLH_02644 3.2e-126 L PFAM Transposase, IS4-like
KCIBCFLH_02645 9.6e-62 L PFAM Transposase, IS4-like
KCIBCFLH_02646 2.9e-51 K UTRA domain
KCIBCFLH_02647 4.3e-166 dtpT E POT family
KCIBCFLH_02648 4.1e-129 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KCIBCFLH_02649 3.4e-15 V AAA domain, putative AbiEii toxin, Type IV TA system
KCIBCFLH_02650 9e-69 V AAA domain, putative AbiEii toxin, Type IV TA system
KCIBCFLH_02651 1.4e-260 L Transposase, IS4 family protein
KCIBCFLH_02652 5.1e-79 V Transport permease protein
KCIBCFLH_02653 7.5e-89 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KCIBCFLH_02654 4e-51 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KCIBCFLH_02655 6e-58 K MarR family
KCIBCFLH_02656 1.5e-229 L Transposase DDE domain group 1
KCIBCFLH_02657 7e-78 S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
KCIBCFLH_02658 1.5e-59 S Predicted membrane protein (DUF2243)
KCIBCFLH_02659 1.7e-66 V ATPases associated with a variety of cellular activities
KCIBCFLH_02660 1e-123
KCIBCFLH_02661 3e-248 L PFAM Transposase, IS4-like
KCIBCFLH_02662 1e-125 tetV EGP Transmembrane secretion effector
KCIBCFLH_02663 1.6e-255 ydjE EGP Major facilitator superfamily
KCIBCFLH_02664 4.1e-156 yxxF EG EamA-like transporter family
KCIBCFLH_02665 1.7e-207 adhC 1.1.1.1 C Zinc-binding dehydrogenase
KCIBCFLH_02667 2.6e-191 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCIBCFLH_02668 2e-29 yetF3 K membrane
KCIBCFLH_02669 9.4e-23 yetF3 K membrane
KCIBCFLH_02672 1.6e-08
KCIBCFLH_02676 8.7e-08
KCIBCFLH_02677 1.7e-07
KCIBCFLH_02685 5.3e-43
KCIBCFLH_02686 4.3e-42 S COG NOG14552 non supervised orthologous group
KCIBCFLH_02687 3.8e-162 ygxA S Nucleotidyltransferase-like
KCIBCFLH_02688 5e-57 ygzB S UPF0295 protein
KCIBCFLH_02689 1.3e-139 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
KCIBCFLH_02690 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KCIBCFLH_02691 2.6e-163 alsR K LysR substrate binding domain
KCIBCFLH_02692 2.5e-84 iprA K Transcriptional regulator
KCIBCFLH_02693 4.3e-111 arcC 2.7.2.2 E Belongs to the carbamate kinase family
KCIBCFLH_02694 8.5e-188 arcD E amino acid
KCIBCFLH_02695 7.5e-146 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCIBCFLH_02696 6.7e-176 arcA 3.5.3.6 E Arginine deiminase
KCIBCFLH_02697 9.8e-82 perR P Belongs to the Fur family
KCIBCFLH_02698 4.4e-100 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
KCIBCFLH_02699 1.5e-65 P Ion transport
KCIBCFLH_02700 2.5e-247 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KCIBCFLH_02701 9.2e-189 ssuA P ABC transporter substrate-binding protein
KCIBCFLH_02702 2.8e-140 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KCIBCFLH_02703 4.2e-144 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KCIBCFLH_02704 8.4e-90 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCIBCFLH_02705 5.2e-221 yitG EGP Major facilitator Superfamily
KCIBCFLH_02706 1.5e-52
KCIBCFLH_02707 4.9e-39 yqhV S Protein of unknown function (DUF2619)
KCIBCFLH_02708 2.2e-188 ygaE S Membrane
KCIBCFLH_02709 2.9e-154 K transcriptional
KCIBCFLH_02710 1.6e-253 sacX 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KCIBCFLH_02711 1.9e-153 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KCIBCFLH_02712 5.1e-209 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KCIBCFLH_02713 1.9e-40 ygaD V ABC transporter
KCIBCFLH_02714 3e-260 ygaD V ABC transporter
KCIBCFLH_02715 1.3e-104 ygaC J Belongs to the UPF0374 family
KCIBCFLH_02716 2.7e-36 ygaB S YgaB-like protein
KCIBCFLH_02717 1.7e-08 sspE S Small, acid-soluble spore protein, gamma-type
KCIBCFLH_02718 5.9e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCIBCFLH_02719 5.4e-164 gltC K Transcriptional regulator
KCIBCFLH_02720 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KCIBCFLH_02721 1.9e-283 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KCIBCFLH_02722 4.7e-51 S YfzA-like protein
KCIBCFLH_02723 3.5e-101 S ABC-2 family transporter protein
KCIBCFLH_02724 5.1e-159 V ABC transporter
KCIBCFLH_02726 3.1e-22 sspK S reproduction
KCIBCFLH_02727 1.7e-187 yfhP S membrane-bound metal-dependent
KCIBCFLH_02728 1.3e-215 mutY L A G-specific
KCIBCFLH_02729 7.1e-199 L COG3039 Transposase and inactivated derivatives, IS5 family
KCIBCFLH_02730 8.3e-51 yfhH S Protein of unknown function (DUF1811)
KCIBCFLH_02731 2.5e-144 recX 2.4.1.337 GT4 S Modulates RecA activity
KCIBCFLH_02733 8.5e-24 yfhD S YfhD-like protein
KCIBCFLH_02734 7.6e-146 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KCIBCFLH_02736 3.2e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KCIBCFLH_02737 3.5e-258 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
KCIBCFLH_02738 1.9e-181 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCIBCFLH_02739 1.3e-108 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KCIBCFLH_02740 2.1e-263 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCIBCFLH_02741 6.8e-207 bacI V COG0577 ABC-type antimicrobial peptide transport system, permease component
KCIBCFLH_02742 2.1e-120 V ATPases associated with a variety of cellular activities
KCIBCFLH_02743 2.2e-188 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCIBCFLH_02745 1.1e-07
KCIBCFLH_02746 1.2e-86 S Stage II sporulation protein M
KCIBCFLH_02747 2e-126 V ABC transporter
KCIBCFLH_02749 6.1e-44 S Bacteriocin class IId cyclical uberolysin-like
KCIBCFLH_02751 0.0 XK27_10205
KCIBCFLH_02753 3.4e-61
KCIBCFLH_02754 7e-127 V AAA domain, putative AbiEii toxin, Type IV TA system
KCIBCFLH_02756 5.4e-113 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KCIBCFLH_02757 0.0 comP 2.7.13.3 T Histidine kinase
KCIBCFLH_02759 4e-164 comQ H Belongs to the FPP GGPP synthase family
KCIBCFLH_02760 1.9e-127 ywdH 1.2.1.3, 1.2.1.71 C Belongs to the aldehyde dehydrogenase family
KCIBCFLH_02761 1.4e-209 acrA1_1 Q Male sterility protein
KCIBCFLH_02762 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KCIBCFLH_02764 2.6e-243 mcpA NT chemotaxis protein
KCIBCFLH_02765 1.6e-182 serA1 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCIBCFLH_02766 1.1e-222 dhsS 1.12.1.2 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KCIBCFLH_02767 5e-301 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCIBCFLH_02768 5.9e-183 S Phosphotransferase system, EIIC
KCIBCFLH_02769 1e-220 2.6.1.9 S HAD-hyrolase-like
KCIBCFLH_02770 8.5e-193 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCIBCFLH_02771 1.6e-111 leuD 4.2.1.33, 4.2.1.35, 4.2.1.36 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCIBCFLH_02772 4.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCIBCFLH_02773 2.9e-204 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KCIBCFLH_02774 4e-284 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCIBCFLH_02775 3e-195 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCIBCFLH_02776 1.1e-84 ilvN 2.2.1.6 E Acetolactate synthase
KCIBCFLH_02777 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KCIBCFLH_02778 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KCIBCFLH_02779 2.5e-245 braB E Component of the transport system for branched-chain amino acids
KCIBCFLH_02780 4.8e-154 T STAS domain
KCIBCFLH_02781 8.7e-245
KCIBCFLH_02782 7.4e-252 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KCIBCFLH_02783 1.2e-104 yetJ S Belongs to the BI1 family
KCIBCFLH_02784 5.3e-214 yxjG 2.1.1.14 E Methionine synthase
KCIBCFLH_02785 6.8e-218 yhjX P Major facilitator superfamily
KCIBCFLH_02786 3.6e-137 ypdB T LytTr DNA-binding domain
KCIBCFLH_02787 0.0 ypdA 2.7.13.3 T Signal transduction histidine kinase
KCIBCFLH_02788 1.2e-196 ansA 3.5.1.1 EJ L-asparaginase
KCIBCFLH_02791 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KCIBCFLH_02792 7.4e-106 yhgD K Transcriptional regulator
KCIBCFLH_02793 2.6e-276 yhgE S YhgE Pip N-terminal domain protein
KCIBCFLH_02794 5.2e-265 S Protein of unknown function (DUF2397)
KCIBCFLH_02795 1.6e-229 S Protein of unknown function (DUF2398)
KCIBCFLH_02796 0.0 D Putative exonuclease SbcCD, C subunit
KCIBCFLH_02797 2e-252 S Protein of unknown function N-terminus (DUF3323)
KCIBCFLH_02798 5.5e-86
KCIBCFLH_02800 3.8e-195 NT chemotaxis protein
KCIBCFLH_02801 6.7e-156 yoaT S Protein of unknown function (DUF817)
KCIBCFLH_02802 1.2e-29 yozG K Transcriptional regulator
KCIBCFLH_02803 6.6e-76 yoaS S Protein of unknown function (DUF2975)
KCIBCFLH_02804 1.1e-54
KCIBCFLH_02805 5.6e-237 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KCIBCFLH_02806 1.8e-73 yqgC S protein conserved in bacteria
KCIBCFLH_02807 8.8e-265 ydbT S Bacterial PH domain
KCIBCFLH_02808 7.7e-88 S Bacterial PH domain
KCIBCFLH_02809 1.2e-88 S AAA domain
KCIBCFLH_02810 1.5e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
KCIBCFLH_02811 5.2e-262 proP EGP Transporter
KCIBCFLH_02812 7.9e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCIBCFLH_02813 1.9e-54 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCIBCFLH_02814 1.2e-143 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KCIBCFLH_02815 1.3e-126 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KCIBCFLH_02816 2.3e-187 2.3.1.180 I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
KCIBCFLH_02817 2.7e-58
KCIBCFLH_02819 2.5e-250 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KCIBCFLH_02822 1.6e-305 lmrA 3.6.3.44 V ABC transporter
KCIBCFLH_02823 1.3e-100 K Iron dependent repressor, N-terminal DNA binding domain
KCIBCFLH_02824 4.9e-41
KCIBCFLH_02825 7.5e-258 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCIBCFLH_02826 5.4e-153 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KCIBCFLH_02827 5.3e-147 pdaA G deacetylase
KCIBCFLH_02828 6.8e-27 yfjT
KCIBCFLH_02829 2.6e-146 yfkD S YfkD-like protein
KCIBCFLH_02830 1.7e-172 cax P COG0387 Ca2 H antiporter
KCIBCFLH_02831 3.1e-220 yfkF EGP Major facilitator Superfamily
KCIBCFLH_02832 2.8e-146 yihY S Belongs to the UPF0761 family
KCIBCFLH_02833 5.2e-31 yfkK S Belongs to the UPF0435 family
KCIBCFLH_02834 1.2e-143 map 3.4.11.18 E Methionine aminopeptidase
KCIBCFLH_02835 9.2e-92 yfkM 3.5.1.124 S protease
KCIBCFLH_02836 9.4e-123 motB N Flagellar motor protein
KCIBCFLH_02837 2.8e-135 motA N flagellar motor
KCIBCFLH_02838 7.9e-58 yhdN S Domain of unknown function (DUF1992)
KCIBCFLH_02840 3.1e-59 yeaO S Protein of unknown function, DUF488
KCIBCFLH_02841 3.7e-227 EGP Major facilitator Superfamily
KCIBCFLH_02842 1.4e-144 dksA T COG1734 DnaK suppressor protein
KCIBCFLH_02843 3.7e-85 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KCIBCFLH_02844 2.2e-182 mreB D Rod-share determining protein MreBH
KCIBCFLH_02845 2.7e-168 yuaG S protein conserved in bacteria
KCIBCFLH_02846 1e-88 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KCIBCFLH_02847 3e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KCIBCFLH_02848 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KCIBCFLH_02849 2.1e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KCIBCFLH_02850 4.2e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KCIBCFLH_02851 1.3e-102 4.2.1.1 P Reversible hydration of carbon dioxide
KCIBCFLH_02853 9e-127 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KCIBCFLH_02855 1e-295 K helix_turn_helix, Lux Regulon
KCIBCFLH_02856 3.1e-107 che
KCIBCFLH_02857 1.7e-67 S response to pH
KCIBCFLH_02858 1e-94
KCIBCFLH_02859 2.6e-252 L PFAM Transposase, IS4-like
KCIBCFLH_02861 5.5e-156 ypuA S Secreted protein
KCIBCFLH_02862 3.7e-218 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KCIBCFLH_02863 3.8e-219 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KCIBCFLH_02864 1.5e-109 cobC 3.1.3.3, 3.1.3.73, 5.4.2.12 G Histidine phosphatase superfamily (branch 1)
KCIBCFLH_02865 8.9e-69 K Transcriptional
KCIBCFLH_02866 4.4e-39 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCIBCFLH_02867 1.7e-161 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCIBCFLH_02868 1.3e-98 cas4 3.1.12.1 L RecB family exonuclease
KCIBCFLH_02869 1.2e-133 csd2 L CRISPR-associated protein
KCIBCFLH_02870 1.1e-270 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
KCIBCFLH_02871 1.2e-116 cas5d S CRISPR-associated protein (Cas_Cas5)
KCIBCFLH_02872 0.0 cas3 L Metal dependent phosphohydrolases with conserved 'HD' motif.
KCIBCFLH_02873 0.0 snf 2.7.11.1 L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KCIBCFLH_02874 5e-265 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_02875 3.6e-108 C Nitroreductase family
KCIBCFLH_02876 9.1e-89 1.8.5.2 S DoxX
KCIBCFLH_02877 7.8e-191 fni 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KCIBCFLH_02878 2.5e-118 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KCIBCFLH_02879 6e-35 yoeD G Helix-turn-helix domain
KCIBCFLH_02880 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KCIBCFLH_02881 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KCIBCFLH_02882 9.3e-133 fruR K Transcriptional regulator
KCIBCFLH_02883 1e-201 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KCIBCFLH_02884 1.6e-94 D Hemerythrin HHE cation binding
KCIBCFLH_02885 3.3e-152 yidA S hydrolases of the HAD superfamily
KCIBCFLH_02886 3.5e-57 ygbA S Nitrous oxide-stimulated promoter
KCIBCFLH_02887 1.7e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system
KCIBCFLH_02888 2.4e-273 iolT EGP Major facilitator Superfamily
KCIBCFLH_02889 6.3e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KCIBCFLH_02891 3.1e-72 ywnF S Family of unknown function (DUF5392)
KCIBCFLH_02892 2.4e-136 ywaC 2.7.6.5 S protein conserved in bacteria
KCIBCFLH_02893 2e-250 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KCIBCFLH_02895 1.4e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
KCIBCFLH_02896 1.6e-100 dhaL 2.7.1.121 S Dak2
KCIBCFLH_02897 3.5e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
KCIBCFLH_02898 1.3e-174 pfoS S Phosphotransferase system, EIIC
KCIBCFLH_02900 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KCIBCFLH_02901 2.1e-236 E COG1113 Gamma-aminobutyrate permease and related permeases
KCIBCFLH_02903 4.4e-150 ytnM S membrane transporter protein
KCIBCFLH_02904 1.6e-225 ywdJ F Xanthine uracil
KCIBCFLH_02905 0.0 yjcD 3.6.4.12 L DNA helicase
KCIBCFLH_02906 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_02907 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCIBCFLH_02909 9.4e-98 O HI0933-like protein
KCIBCFLH_02911 5.5e-77 K Acetyltransferase (GNAT) domain
KCIBCFLH_02912 5.3e-289 yngE I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KCIBCFLH_02913 3.6e-132 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KCIBCFLH_02915 9.9e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KCIBCFLH_02916 7.7e-13 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KCIBCFLH_02917 2.2e-246 yngH 6.3.4.14, 6.3.4.6, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KCIBCFLH_02918 7.7e-216 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KCIBCFLH_02919 0.0 6.2.1.1 I AMP-dependent synthetase
KCIBCFLH_02920 5.1e-303 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KCIBCFLH_02921 1.4e-251 zraR KT Transcriptional regulator
KCIBCFLH_02922 1.1e-231 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KCIBCFLH_02923 1e-243 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KCIBCFLH_02924 2.1e-133 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KCIBCFLH_02925 4.3e-272 hsdM 2.1.1.72 V Type I restriction-modification system
KCIBCFLH_02927 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
KCIBCFLH_02928 7.3e-275 lysP E amino acid
KCIBCFLH_02929 4e-108 K Transcriptional regulator
KCIBCFLH_02930 1.1e-199 ybhR V COG0842 ABC-type multidrug transport system, permease component
KCIBCFLH_02932 3.3e-127 V COG1131 ABC-type multidrug transport system, ATPase component
KCIBCFLH_02933 8e-70 S Hemerythrin HHE cation binding domain
KCIBCFLH_02934 3e-50
KCIBCFLH_02935 1.6e-42
KCIBCFLH_02936 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KCIBCFLH_02937 1.1e-223 sfcA 1.1.1.38 C Malate dehydrogenase
KCIBCFLH_02938 4.2e-33 yflS P Sodium:sulfate symporter transmembrane region
KCIBCFLH_02939 2.7e-160 yflS P Sodium:sulfate symporter transmembrane region
KCIBCFLH_02940 1.7e-162 fda 4.1.2.13 G Belongs to the class I fructose-bisphosphate aldolase family
KCIBCFLH_02941 1.1e-231 L PFAM transposase IS4 family protein
KCIBCFLH_02942 3.7e-260 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_02943 2.9e-239 hutH 4.3.1.3 E Histidine ammonia-lyase
KCIBCFLH_02944 2.6e-109 MA20_34180 P ATPases associated with a variety of cellular activities
KCIBCFLH_02945 1.1e-105 MA20_34185 P Binding-protein-dependent transport system inner membrane component
KCIBCFLH_02946 4.4e-151 hutI 3.5.2.7 Q Amidohydrolase family
KCIBCFLH_02947 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KCIBCFLH_02948 5.9e-135 MA20_34190 P NMT1-like family
KCIBCFLH_02949 1.4e-109 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCIBCFLH_02950 1.9e-52 S Protein of unknown function DUF126
KCIBCFLH_02951 2.5e-209 S Protein of unknown function (DUF521)
KCIBCFLH_02952 2e-178 3.5.4.28, 3.5.4.31 F Amidohydrolase family
KCIBCFLH_02953 2.4e-68 amaB 3.5.1.6, 3.5.1.87 E Peptidase family M28
KCIBCFLH_02954 5.8e-59 amaB 3.5.1.6, 3.5.1.87 E Peptidase family M28
KCIBCFLH_02955 7.8e-102 K Transcriptional regulator
KCIBCFLH_02956 2.4e-79 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KCIBCFLH_02957 1.8e-55 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KCIBCFLH_02958 7.5e-140 rbsC G Belongs to the binding-protein-dependent transport system permease family
KCIBCFLH_02959 4.3e-47 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KCIBCFLH_02960 3e-248 L PFAM Transposase, IS4-like
KCIBCFLH_02961 0.0 L Domain of unknown function (DUF4277)
KCIBCFLH_02962 1.5e-40 S Protein of unknown function, DUF600
KCIBCFLH_02965 8.9e-198 mcrC V McrBC 5-methylcytosine restriction system component
KCIBCFLH_02966 0.0 mcrB V AAA domain (dynein-related subfamily)
KCIBCFLH_02967 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KCIBCFLH_02968 4.8e-110 3.1.21.3 V PFAM restriction modification system DNA specificity domain
KCIBCFLH_02969 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
KCIBCFLH_02970 1.5e-26
KCIBCFLH_02971 4.1e-113 E LysE type translocator
KCIBCFLH_02972 1.7e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KCIBCFLH_02973 1e-79 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KCIBCFLH_02974 8.7e-150 3.2.1.122, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KCIBCFLH_02975 1.6e-266 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_02976 1.9e-258 L PFAM Transposase, IS4-like
KCIBCFLH_02977 2.3e-192 mccF 3.4.17.13 V peptidase S66
KCIBCFLH_02979 1.1e-286 L Transposase
KCIBCFLH_02980 1.2e-40 hsdM 2.1.1.72 V Type I restriction-modification system
KCIBCFLH_02981 9.7e-220 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KCIBCFLH_02982 5.2e-206 L PFAM Transposase, IS4-like
KCIBCFLH_02983 6.4e-104 S YqcI/YcgG family
KCIBCFLH_02984 2.5e-98 L Integrase
KCIBCFLH_02985 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KCIBCFLH_02986 1.1e-62 K transcriptional
KCIBCFLH_02989 6.5e-284 L Transposase
KCIBCFLH_02990 4.1e-164 mleR K LysR substrate binding domain
KCIBCFLH_02991 9.4e-91 nrdG 1.97.1.4 O 4Fe-4S single cluster domain
KCIBCFLH_02992 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KCIBCFLH_02993 2.8e-207 U protein localization to endoplasmic reticulum
KCIBCFLH_02994 2.2e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KCIBCFLH_02995 9.1e-75 KT Sugar diacid utilization regulator
KCIBCFLH_02996 8.3e-196 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KCIBCFLH_02997 1.7e-163 EG Gluconate proton symporter
KCIBCFLH_02999 2.9e-157 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KCIBCFLH_03000 8.8e-149 rbsC G Belongs to the binding-protein-dependent transport system permease family
KCIBCFLH_03001 1.2e-280 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KCIBCFLH_03002 3.2e-68 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KCIBCFLH_03003 1.7e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCIBCFLH_03004 2.6e-180 rbsR K transcriptional
KCIBCFLH_03008 2.3e-159 S transposase or invertase
KCIBCFLH_03009 9e-89 1.4.3.5 S Pyridoxamine 5'phosphate oxidase-like, FMN-binding
KCIBCFLH_03010 7.2e-08 S transposase or invertase
KCIBCFLH_03011 1.2e-153 S transposase or invertase
KCIBCFLH_03012 3.7e-108 ycnI S Domain of unkown function (DUF1775)
KCIBCFLH_03013 5.4e-303 ycnJ P protein, homolog of Cu resistance protein CopC
KCIBCFLH_03014 4.7e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCIBCFLH_03015 6.7e-130 5.1.3.1 G Ribulose-phosphate 3 epimerase family
KCIBCFLH_03016 1.1e-178 rbsR K transcriptional
KCIBCFLH_03017 1.8e-257 G PTS system sugar-specific permease component
KCIBCFLH_03018 1.7e-51
KCIBCFLH_03019 3.5e-09 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KCIBCFLH_03020 1.6e-233 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KCIBCFLH_03021 1.2e-216 2.3.1.179 IQ Beta-ketoacyl synthase, C-terminal domain
KCIBCFLH_03022 1.3e-28 cspL K Cold shock
KCIBCFLH_03023 3.6e-178 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KCIBCFLH_03024 1.9e-91 ydfC EG EamA-like transporter family
KCIBCFLH_03026 7.9e-145 G Major Facilitator Superfamily
KCIBCFLH_03028 9e-162 ydcZ S Putative inner membrane exporter, YdcZ
KCIBCFLH_03029 0.0 nagA 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KCIBCFLH_03030 0.0 ampC V Belongs to the UPF0214 family
KCIBCFLH_03031 3.9e-245 ybbC 3.2.1.52 S protein conserved in bacteria
KCIBCFLH_03033 1e-72
KCIBCFLH_03034 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KCIBCFLH_03035 2.4e-309 yfiB V ABC transporter
KCIBCFLH_03036 7.2e-80 K helix_turn_helix multiple antibiotic resistance protein
KCIBCFLH_03037 3.2e-109 3.1.3.18 S Haloacid dehalogenase-like hydrolase
KCIBCFLH_03038 6.9e-253 L PFAM Transposase, IS4-like
KCIBCFLH_03039 3e-105 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KCIBCFLH_03040 1.5e-60 QT Purine catabolism regulatory protein-like family
KCIBCFLH_03041 2.4e-84 QT Purine catabolism regulatory protein-like family
KCIBCFLH_03042 8.4e-113 S Protein of unknown function (DUF3237)
KCIBCFLH_03043 8e-282 estC CE10 I Belongs to the type-B carboxylesterase lipase family
KCIBCFLH_03044 7.2e-275 3.5.1.4 J Belongs to the amidase family
KCIBCFLH_03045 6.9e-181 EGP Major facilitator Superfamily
KCIBCFLH_03046 5.6e-39 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C belongs to the aldehyde dehydrogenase family
KCIBCFLH_03047 6.7e-111 P Integral membrane protein TerC family
KCIBCFLH_03048 2.7e-67
KCIBCFLH_03050 2e-145 XK27_04815 S Membrane transport protein
KCIBCFLH_03051 0.0
KCIBCFLH_03052 0.0 V COG1401 GTPase subunit of restriction endonuclease
KCIBCFLH_03053 3.9e-145
KCIBCFLH_03054 2.2e-306 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KCIBCFLH_03055 6.4e-24 S Uncharacterized small protein (DUF2292)
KCIBCFLH_03056 1.4e-95 ssuE 1.5.1.38 S FMN reductase
KCIBCFLH_03057 5.1e-139 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
KCIBCFLH_03058 6.6e-123 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KCIBCFLH_03059 2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KCIBCFLH_03060 6.1e-169 P ABC transporter substrate-binding protein
KCIBCFLH_03061 1e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KCIBCFLH_03063 1.1e-53 S SMI1-KNR4 cell-wall
KCIBCFLH_03064 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KCIBCFLH_03065 2e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KCIBCFLH_03066 1.3e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCIBCFLH_03067 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KCIBCFLH_03068 5.2e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KCIBCFLH_03069 2.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KCIBCFLH_03070 1.8e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KCIBCFLH_03071 6.4e-213 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KCIBCFLH_03072 8.6e-219 pbuO_1 S permease
KCIBCFLH_03073 8.8e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KCIBCFLH_03074 8e-166 S Protein of unknown function (DUF979)
KCIBCFLH_03075 6.5e-117 S Protein of unknown function (DUF969)
KCIBCFLH_03076 2.6e-135 ycsF S Belongs to the UPF0271 (lamB) family
KCIBCFLH_03077 1.2e-180 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KCIBCFLH_03078 2.4e-135 kipI 3.5.1.54, 6.3.4.6 E Allophanate hydrolase subunit 1
KCIBCFLH_03079 1.2e-214 EGP Major facilitator Superfamily
KCIBCFLH_03080 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
KCIBCFLH_03081 3.7e-131 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KCIBCFLH_03082 7.6e-115 artQ E COG0765 ABC-type amino acid transport system, permease component
KCIBCFLH_03083 2e-135 artP ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KCIBCFLH_03084 3.2e-217 hipO3 3.5.1.47 S amidohydrolase
KCIBCFLH_03085 4.3e-113 mdeA 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KCIBCFLH_03086 1.2e-47
KCIBCFLH_03087 0.0 L Domain of unknown function (DUF4277)
KCIBCFLH_03088 5.7e-104 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KCIBCFLH_03089 1.4e-93 S Psort location CytoplasmicMembrane, score
KCIBCFLH_03090 1.1e-56 I Domain of unknown function (DUF4430)
KCIBCFLH_03091 4.6e-107 M FFAT motif binding
KCIBCFLH_03092 2.3e-248 L PFAM Transposase, IS4-like
KCIBCFLH_03093 0.0 htpG O Molecular chaperone. Has ATPase activity
KCIBCFLH_03094 1.8e-42 S Protein of unknown function, DUF600
KCIBCFLH_03095 1.1e-197 L DDE superfamily endonuclease
KCIBCFLH_03096 3.8e-113 crtF 2.1.1.210, 2.1.1.281, 2.1.1.79 M Methyltransferase
KCIBCFLH_03097 2.9e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KCIBCFLH_03098 4.3e-37 S Protein of unknown function DUF86
KCIBCFLH_03099 4.2e-40 S Nucleotidyltransferase domain
KCIBCFLH_03100 2e-191 adhP 1.1.1.1 C alcohol dehydrogenase
KCIBCFLH_03102 4.1e-83 L Transposase
KCIBCFLH_03103 1.3e-136 L Transposase
KCIBCFLH_03104 3.1e-270 L Domain of unknown function (DUF4277)
KCIBCFLH_03105 5.2e-15 S Protein of unknown function (DUF2750)
KCIBCFLH_03106 8.5e-142 IQ Enoyl-(Acyl carrier protein) reductase
KCIBCFLH_03107 1.1e-158 S Protein of unknown function
KCIBCFLH_03108 2.3e-141 S Protein of unknown function (DUF2961)
KCIBCFLH_03109 0.0 L Domain of unknown function (DUF4277)
KCIBCFLH_03110 2.5e-73 3.2.1.20 GH31 S Protein of unknown function (DUF2961)
KCIBCFLH_03111 0.0
KCIBCFLH_03112 6.7e-50
KCIBCFLH_03113 1e-145 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
KCIBCFLH_03114 1e-129 G PTS system sorbose-specific iic component
KCIBCFLH_03115 9.7e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
KCIBCFLH_03116 1.2e-71 2.7.1.191 G PTS system fructose IIA component
KCIBCFLH_03117 3.4e-107 K PFAM sigma-54 factor interaction domain-containing protein
KCIBCFLH_03118 1.2e-266 K PTS system fructose IIA component
KCIBCFLH_03119 2.3e-259 L Transposase
KCIBCFLH_03120 1.5e-09 L DDE superfamily endonuclease
KCIBCFLH_03122 1e-53 3.5.1.19 Q Isochorismatase family
KCIBCFLH_03123 5.7e-94 S S4 RNA-binding domain
KCIBCFLH_03124 1.2e-191
KCIBCFLH_03125 4.1e-38 yxjI S LURP-one-related
KCIBCFLH_03126 3.5e-17 yxjI S LURP-one-related
KCIBCFLH_03128 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
KCIBCFLH_03129 5.4e-264 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCIBCFLH_03130 1.6e-266 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCIBCFLH_03131 4.2e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KCIBCFLH_03132 1.4e-155 Q N-acetyltransferase
KCIBCFLH_03135 3.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCIBCFLH_03136 2.9e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KCIBCFLH_03137 1.5e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCIBCFLH_03138 4.9e-246 aceA 4.1.3.1 C Isocitrate lyase
KCIBCFLH_03139 0.0 aceB 2.3.3.9 C Belongs to the malate synthase family
KCIBCFLH_03140 3.4e-219 camS S COG4851 Protein involved in sex pheromone biosynthesis
KCIBCFLH_03141 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCIBCFLH_03142 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KCIBCFLH_03143 1.4e-130 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KCIBCFLH_03144 1.1e-53 yerC S protein conserved in bacteria
KCIBCFLH_03145 1.9e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
KCIBCFLH_03146 0.0 yerA 3.5.4.2 F adenine deaminase
KCIBCFLH_03147 4.2e-36 S Protein of unknown function (DUF2892)
KCIBCFLH_03148 6.9e-226 purD 6.3.4.13 F Belongs to the GARS family
KCIBCFLH_03149 1.7e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KCIBCFLH_03150 3e-102 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCIBCFLH_03151 1.1e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KCIBCFLH_03152 2.3e-270 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KCIBCFLH_03153 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCIBCFLH_03154 2.8e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCIBCFLH_03155 9e-40 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCIBCFLH_03156 1e-125 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KCIBCFLH_03157 5.1e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCIBCFLH_03158 2.2e-218 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KCIBCFLH_03159 1.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KCIBCFLH_03160 5.4e-30 yebG S NETI protein
KCIBCFLH_03161 3.1e-90 yebE S UPF0316 protein
KCIBCFLH_03162 1.3e-131 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KCIBCFLH_03163 5.7e-43 nagE 2.7.1.193, 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KCIBCFLH_03165 2.9e-33 glvR K Helix-turn-helix domain, rpiR family
KCIBCFLH_03166 4.1e-199 glvC 2.7.1.199, 2.7.1.208 G pts system
KCIBCFLH_03167 6e-191 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
KCIBCFLH_03168 1.7e-41
KCIBCFLH_03169 4.3e-42 S COG NOG14552 non supervised orthologous group
KCIBCFLH_03170 2.7e-222 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KCIBCFLH_03171 0.0 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KCIBCFLH_03172 2.5e-155 glcT K antiterminator
KCIBCFLH_03173 2.6e-231 pbuG S permease
KCIBCFLH_03175 0.0 ywjA V ABC transporter
KCIBCFLH_03176 1.2e-214 ynfM EGP Major facilitator Superfamily
KCIBCFLH_03177 4.3e-118 yfiK K Regulator
KCIBCFLH_03178 5.4e-198 T Histidine kinase
KCIBCFLH_03179 4.4e-169 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
KCIBCFLH_03180 9.3e-198 yfiM V ABC-2 type transporter
KCIBCFLH_03181 1.5e-206 yfiN V COG0842 ABC-type multidrug transport system, permease component
KCIBCFLH_03182 4.7e-226 1.13.11.4 Q Cupin domain
KCIBCFLH_03183 1.2e-88 S DinB superfamily
KCIBCFLH_03184 1.4e-178 3.7.1.5 Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KCIBCFLH_03185 1.3e-142 K helix_turn_helix isocitrate lyase regulation
KCIBCFLH_03186 5.4e-98
KCIBCFLH_03187 1.1e-156 1.14.13.127 CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KCIBCFLH_03188 4.3e-76 ysmA 3.1.2.23 S Thioesterase-like superfamily
KCIBCFLH_03189 6.1e-307 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KCIBCFLH_03190 4.5e-219 bktB 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
KCIBCFLH_03191 2.5e-141 4.2.1.17 I Enoyl-CoA hydratase/isomerase
KCIBCFLH_03192 2.4e-156 hbd 1.1.1.157 I Dehydrogenase
KCIBCFLH_03193 6.4e-32 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 QT Domain present in phytochromes and cGMP-specific phosphodiesterases.
KCIBCFLH_03194 3.8e-132 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 QT Domain present in phytochromes and cGMP-specific phosphodiesterases.
KCIBCFLH_03195 1.1e-216 benK EGP Major facilitator Superfamily
KCIBCFLH_03196 3.9e-142 K helix_turn_helix isocitrate lyase regulation
KCIBCFLH_03197 9.5e-163 3.7.1.20 Q Fumarylacetoacetate (FAA) hydrolase family
KCIBCFLH_03198 1.7e-59 1.13.11.4 Q AraC-like ligand binding domain
KCIBCFLH_03199 4e-139 1.13.11.4 Q AraC-like ligand binding domain
KCIBCFLH_03200 9.9e-256 ybhI P Sodium:sulfate symporter transmembrane region
KCIBCFLH_03201 1.3e-49 L deoxyribonuclease I activity
KCIBCFLH_03202 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
KCIBCFLH_03205 1.7e-178 tnp4 L Transposase, Mutator family
KCIBCFLH_03206 6.6e-140
KCIBCFLH_03207 9.2e-127 yhcG V ABC transporter, ATP-binding protein
KCIBCFLH_03208 1.6e-58 yhcF K Transcriptional regulator
KCIBCFLH_03209 4.6e-97 padR K transcriptional
KCIBCFLH_03210 5.1e-95 padC Q Phenolic acid decarboxylase
KCIBCFLH_03211 7.4e-115 ywnB S NAD(P)H-binding
KCIBCFLH_03212 1.4e-72 ywnA K Transcriptional regulator
KCIBCFLH_03213 9e-181 L Mu transposase, C-terminal
KCIBCFLH_03214 1.3e-63 L Mu transposase, C-terminal
KCIBCFLH_03215 2.6e-149 U AAA domain
KCIBCFLH_03216 2.1e-13 S transposase or invertase
KCIBCFLH_03217 1.3e-155 S transposase or invertase
KCIBCFLH_03218 6.9e-36 yeeD O Belongs to the sulfur carrier protein TusA family
KCIBCFLH_03219 6.5e-193 yeeE S Sulphur transport
KCIBCFLH_03220 6.6e-242 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KCIBCFLH_03221 2.7e-171 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCIBCFLH_03222 1.5e-08
KCIBCFLH_03223 6.3e-30 ybxH S Family of unknown function (DUF5370)
KCIBCFLH_03224 1.9e-189 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KCIBCFLH_03225 8.7e-139 fecE 3.6.3.34 HP ABC transporter
KCIBCFLH_03226 9e-174 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCIBCFLH_03227 3.1e-93
KCIBCFLH_03229 7.9e-149 emrB P Major facilitator superfamily
KCIBCFLH_03230 4.8e-60 EGP Major facilitator Superfamily
KCIBCFLH_03231 1.4e-27 K Helix-turn-helix domain
KCIBCFLH_03232 4.7e-31
KCIBCFLH_03233 2.7e-31 S Domain of unknown function (DUF4177)
KCIBCFLH_03234 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KCIBCFLH_03235 1.4e-153 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KCIBCFLH_03236 5.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCIBCFLH_03237 8.9e-109 pncA Q COG1335 Amidases related to nicotinamidase
KCIBCFLH_03238 1e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KCIBCFLH_03239 0.0 ykoS
KCIBCFLH_03240 1.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KCIBCFLH_03241 2e-67 yngA S GtrA-like protein
KCIBCFLH_03242 5.3e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KCIBCFLH_03243 9.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KCIBCFLH_03244 8.1e-126 ydiL S CAAX protease self-immunity
KCIBCFLH_03245 1.3e-27 S Domain of unknown function (DUF4305)
KCIBCFLH_03246 5.1e-131 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCIBCFLH_03247 2.7e-123 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KCIBCFLH_03248 1.6e-08 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KCIBCFLH_03249 0.0 ydiF S ABC transporter
KCIBCFLH_03250 7e-08 ydiF S ABC transporter
KCIBCFLH_03251 8.9e-184 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KCIBCFLH_03252 4.5e-82 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KCIBCFLH_03253 5.7e-129 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KCIBCFLH_03254 9e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KCIBCFLH_03256 5.3e-43
KCIBCFLH_03257 4.3e-42 S COG NOG14552 non supervised orthologous group
KCIBCFLH_03262 1.6e-08
KCIBCFLH_03270 5.1e-92 ydcK S Belongs to the SprT family
KCIBCFLH_03271 0.0 yhgF K COG2183 Transcriptional accessory protein
KCIBCFLH_03272 7.3e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KCIBCFLH_03273 1.3e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KCIBCFLH_03274 2.3e-81 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KCIBCFLH_03275 3.6e-61 rsbV T Belongs to the anti-sigma-factor antagonist family
KCIBCFLH_03276 6.4e-190 rsbU 3.1.3.3 KT phosphatase
KCIBCFLH_03277 2e-70 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KCIBCFLH_03278 2.1e-55 rsbS T antagonist
KCIBCFLH_03279 3e-153 rsbR T Positive regulator of sigma-B
KCIBCFLH_03280 7.2e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KCIBCFLH_03281 2e-40 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KCIBCFLH_03282 1.7e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KCIBCFLH_03283 8.4e-190 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KCIBCFLH_03284 1.2e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KCIBCFLH_03285 3.8e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KCIBCFLH_03286 1.7e-260 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KCIBCFLH_03287 2.7e-30
KCIBCFLH_03288 3.4e-38
KCIBCFLH_03289 2.1e-58
KCIBCFLH_03290 3.2e-107 E Lysine exporter protein LysE YggA
KCIBCFLH_03291 2.7e-123 otsB2 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KCIBCFLH_03292 2.7e-177 yvdE K Transcriptional regulator
KCIBCFLH_03293 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KCIBCFLH_03294 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KCIBCFLH_03295 1.1e-242 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KCIBCFLH_03296 2.2e-243 malC P COG1175 ABC-type sugar transport systems, permease components
KCIBCFLH_03297 5.1e-156 malD P transport
KCIBCFLH_03298 2.9e-143 malA S Protein of unknown function (DUF1189)
KCIBCFLH_03299 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KCIBCFLH_03300 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KCIBCFLH_03301 2.9e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KCIBCFLH_03302 4.8e-204 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KCIBCFLH_03303 2.1e-148
KCIBCFLH_03304 2.7e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KCIBCFLH_03305 7.8e-82 cueR K transcriptional
KCIBCFLH_03306 1.7e-249 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KCIBCFLH_03308 3.2e-267 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_03309 4.9e-309 ywqB S Zinc finger, swim domain protein
KCIBCFLH_03310 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KCIBCFLH_03312 3.3e-71 ywpF S YwpF-like protein
KCIBCFLH_03313 1.3e-63 ssbB L Single-stranded DNA-binding protein
KCIBCFLH_03315 3.5e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KCIBCFLH_03316 5.5e-147 flhP N flagellar basal body
KCIBCFLH_03317 4.9e-145 flhO N flagellar basal body
KCIBCFLH_03318 6.8e-93 mbl D Rod shape-determining protein
KCIBCFLH_03319 9.8e-62 mbl D Rod shape-determining protein
KCIBCFLH_03321 1.3e-41 spoIIID K Stage III sporulation protein D
KCIBCFLH_03322 1.6e-127 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KCIBCFLH_03323 3.4e-183 spoIID D Stage II sporulation protein D
KCIBCFLH_03324 8.8e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCIBCFLH_03325 2.5e-135 ywmB S TATA-box binding
KCIBCFLH_03327 1.4e-34 ywzB S membrane
KCIBCFLH_03328 6.3e-59 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KCIBCFLH_03329 2.7e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KCIBCFLH_03330 5e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KCIBCFLH_03331 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCIBCFLH_03332 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCIBCFLH_03333 1e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KCIBCFLH_03334 1.3e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCIBCFLH_03335 8.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
KCIBCFLH_03336 4.1e-57 atpI S ATP synthase I chain
KCIBCFLH_03337 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCIBCFLH_03338 1.2e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCIBCFLH_03339 9.1e-101 ywlG S Belongs to the UPF0340 family
KCIBCFLH_03340 1.4e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KCIBCFLH_03342 8.8e-176 mcpA NT Chemotaxis
KCIBCFLH_03343 7e-80 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCIBCFLH_03344 3.7e-91 mntP P Probably functions as a manganese efflux pump
KCIBCFLH_03345 2.2e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KCIBCFLH_03346 7.4e-122 spoIIR S stage II sporulation protein R
KCIBCFLH_03347 6.3e-162 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KCIBCFLH_03348 6.6e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCIBCFLH_03349 5.3e-07
KCIBCFLH_03350 1.7e-110 tdk 2.7.1.21 F thymidine kinase
KCIBCFLH_03351 2.2e-33 rpmE J Ribosomal protein L31
KCIBCFLH_03352 2.3e-248 L PFAM Transposase, IS4-like
KCIBCFLH_03353 2.7e-230 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KCIBCFLH_03354 7.8e-177 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KCIBCFLH_03355 5.6e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCIBCFLH_03356 1.3e-114 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KCIBCFLH_03357 3.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KCIBCFLH_03358 6e-61 spo0F T response regulator
KCIBCFLH_03359 9.8e-219
KCIBCFLH_03360 2.3e-148
KCIBCFLH_03361 4.9e-125 yhcG V ABC transporter, ATP-binding protein
KCIBCFLH_03362 1.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
KCIBCFLH_03363 2.2e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KCIBCFLH_03364 2.7e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KCIBCFLH_03365 1.6e-266 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_03366 9.2e-124 V ATPases associated with a variety of cellular activities
KCIBCFLH_03367 0.0 S FtsX-like permease family
KCIBCFLH_03368 3.9e-265 L Domain of unknown function (DUF4277)
KCIBCFLH_03369 0.0 L Domain of unknown function (DUF4277)
KCIBCFLH_03370 5.6e-22 L Domain of unknown function (DUF4277)
KCIBCFLH_03371 0.0 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KCIBCFLH_03372 5.2e-113 kstR2_2 K Transcriptional regulator
KCIBCFLH_03373 1.8e-212 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KCIBCFLH_03374 3.7e-210 mmgC I acyl-CoA dehydrogenase
KCIBCFLH_03375 9.4e-217 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
KCIBCFLH_03377 0.0 fadF C COG0247 Fe-S oxidoreductase
KCIBCFLH_03378 4.4e-222 cls I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KCIBCFLH_03379 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KCIBCFLH_03380 5.7e-74 ywiB S Domain of unknown function (DUF1934)
KCIBCFLH_03381 4.1e-169 speB 3.5.3.11 E Belongs to the arginase family
KCIBCFLH_03382 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCIBCFLH_03383 5.4e-92 ywhD S YwhD family
KCIBCFLH_03384 7.3e-118 ywhC S Peptidase M50
KCIBCFLH_03385 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KCIBCFLH_03386 3.3e-89 ywgA 2.1.1.72, 3.1.21.3
KCIBCFLH_03387 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
KCIBCFLH_03388 5.7e-100 rsfA S Transcriptional regulator
KCIBCFLH_03389 6.1e-126 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KCIBCFLH_03390 7.8e-177 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KCIBCFLH_03391 3.3e-146 ywfI C May function as heme-dependent peroxidase
KCIBCFLH_03392 1e-58 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KCIBCFLH_03393 3.3e-59 ywdK S small membrane protein
KCIBCFLH_03394 2.2e-38 S Family of unknown function (DUF5327)
KCIBCFLH_03395 1.2e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCIBCFLH_03396 2.5e-56 S Heat induced stress protein YflT
KCIBCFLH_03398 3.5e-19 S Circ_ocin_uber circular bacteriocin, circularin A uberolysin family protein
KCIBCFLH_03399 1.2e-291
KCIBCFLH_03400 2.7e-43 S Stage II sporulation protein M
KCIBCFLH_03401 3.3e-121 V ATPases associated with a variety of cellular activities
KCIBCFLH_03404 2.7e-101 S ABC-2 family transporter protein
KCIBCFLH_03405 2.6e-107 V AAA domain, putative AbiEii toxin, Type IV TA system
KCIBCFLH_03406 1.2e-261 L Transposase, IS4 family protein
KCIBCFLH_03408 8.1e-208
KCIBCFLH_03409 1.6e-266 S PFAM Uncharacterised protein family UPF0236
KCIBCFLH_03410 9.6e-152 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KCIBCFLH_03411 3.9e-62 yojF S Protein of unknown function (DUF1806)
KCIBCFLH_03412 1.1e-129 bshB2 S deacetylase
KCIBCFLH_03413 6.8e-164 ycsE S hydrolases of the HAD superfamily
KCIBCFLH_03414 0.0 recQ 3.6.4.12 L DNA helicase
KCIBCFLH_03415 4e-229 phoA 3.1.3.1 P Belongs to the alkaline phosphatase family
KCIBCFLH_03416 2.8e-154 ybbH_2 K Transcriptional regulator
KCIBCFLH_03417 1.1e-153 S Alpha/beta hydrolase of unknown function (DUF915)
KCIBCFLH_03418 1.3e-13
KCIBCFLH_03419 1.5e-75 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCIBCFLH_03421 2.2e-117 ywbG M effector of murein hydrolase
KCIBCFLH_03422 3.7e-58 ywbH S LrgA family
KCIBCFLH_03423 2.3e-181 ywbI K Transcriptional regulator
KCIBCFLH_03424 0.0 asnO 6.3.5.4 E Asparagine synthase
KCIBCFLH_03425 1.5e-109 S Protein of unknown function (DUF1646)
KCIBCFLH_03427 6.7e-259 L Transposase
KCIBCFLH_03428 8.8e-75 S Threonine/Serine exporter, ThrE
KCIBCFLH_03429 1.9e-130 thrE S Putative threonine/serine exporter
KCIBCFLH_03430 2.1e-207 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KCIBCFLH_03431 0.0 cstA T Carbon starvation protein
KCIBCFLH_03432 1.4e-127 lytT T COG3279 Response regulator of the LytR AlgR family
KCIBCFLH_03433 2.4e-83 lytS 2.7.13.3 T Histidine kinase
KCIBCFLH_03434 5.8e-231 lytS 2.7.13.3 T Histidine kinase
KCIBCFLH_03435 2.7e-141 metQ M Belongs to the nlpA lipoprotein family
KCIBCFLH_03436 4.8e-101 metI P COG2011 ABC-type metal ion transport system, permease component
KCIBCFLH_03437 1.4e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCIBCFLH_03438 1.4e-144 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KCIBCFLH_03439 1.1e-101
KCIBCFLH_03440 2.8e-221 pilM NU Pilus assembly protein
KCIBCFLH_03441 1.8e-240 yisQ V Mate efflux family protein
KCIBCFLH_03442 4.9e-153 M Glycosyl transferase family 8
KCIBCFLH_03443 2.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KCIBCFLH_03444 4.5e-272 EGP Major facilitator Superfamily
KCIBCFLH_03445 3.2e-226 uraA F Xanthine uracil
KCIBCFLH_03446 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KCIBCFLH_03447 2.1e-126 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCIBCFLH_03448 3.5e-300 msbA2 3.6.3.44 V ABC transporter
KCIBCFLH_03449 2.3e-111 yhhQ_2 S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KCIBCFLH_03450 6.4e-98 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KCIBCFLH_03451 0.0 S MMPL domain protein
KCIBCFLH_03452 1.1e-299 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KCIBCFLH_03453 1.3e-41 T diguanylate cyclase activity
KCIBCFLH_03454 1.9e-135 gntR2 K UTRA
KCIBCFLH_03455 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KCIBCFLH_03456 4.4e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KCIBCFLH_03457 5.3e-107 fliY ET Belongs to the bacterial solute-binding protein 3 family
KCIBCFLH_03458 1.5e-91 artQ_1 E amino acid transport system, permease
KCIBCFLH_03459 9.4e-106 glnQ2 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KCIBCFLH_03460 5.2e-239 LYS1 1.5.1.7 E Saccharopine dehydrogenase
KCIBCFLH_03461 3.6e-226 nspC 4.1.1.96 E Pyridoxal-dependent decarboxylase, C-terminal sheet domain
KCIBCFLH_03462 1.6e-207 S Domain of unknown function (DUF1611_N) Rossmann-like domain
KCIBCFLH_03463 3.5e-216 5.1.1.12 E Alanine racemase, N-terminal domain
KCIBCFLH_03464 5.4e-142 cjaA ET Belongs to the bacterial solute-binding protein 3 family
KCIBCFLH_03465 5.8e-132 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
KCIBCFLH_03466 2.6e-102 E amino acid ABC transporter
KCIBCFLH_03467 4.4e-115 papP E amino acid ABC transporter
KCIBCFLH_03468 4.3e-291 mqo 1.1.5.4 S malate quinone oxidoreductase
KCIBCFLH_03469 1.2e-239 kgtP EGP -transporter
KCIBCFLH_03470 1.2e-58 K PadR family transcriptional regulator
KCIBCFLH_03471 4.4e-55 S Protein of unknown function (DUF1048)
KCIBCFLH_03472 1.7e-49 S Protein of unknown function (DUF1048)
KCIBCFLH_03473 5.3e-35 S Protein of unknown function (DUF1048)
KCIBCFLH_03474 6.5e-71 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCIBCFLH_03475 6.8e-181 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KCIBCFLH_03476 1.7e-145 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KCIBCFLH_03477 5.4e-244 yycH S protein conserved in bacteria
KCIBCFLH_03478 0.0 vicK 2.7.13.3 T Histidine kinase
KCIBCFLH_03479 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCIBCFLH_03482 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCIBCFLH_03483 3.7e-249 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KCIBCFLH_03484 1.2e-71 rplI J binds to the 23S rRNA
KCIBCFLH_03485 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KCIBCFLH_03486 1.8e-146 yybS S membrane
KCIBCFLH_03487 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KCIBCFLH_03488 1.5e-86 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KCIBCFLH_03489 5e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KCIBCFLH_03490 7.4e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KCIBCFLH_03491 6.2e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KCIBCFLH_03492 2.6e-115 ribE 2.5.1.9 H Riboflavin synthase
KCIBCFLH_03493 2.3e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KCIBCFLH_03494 5.9e-205 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KCIBCFLH_03495 1.1e-32 yyzM S protein conserved in bacteria
KCIBCFLH_03496 1.1e-161 ykuT M Mechanosensitive ion channel
KCIBCFLH_03497 3.3e-112 yyaC S Sporulation protein YyaC
KCIBCFLH_03498 6.2e-118 ydfK S Protein of unknown function (DUF554)
KCIBCFLH_03499 1.2e-149 spo0J K Belongs to the ParB family
KCIBCFLH_03500 6.9e-136 soj D COG1192 ATPases involved in chromosome partitioning
KCIBCFLH_03501 5.9e-152 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KCIBCFLH_03502 1.8e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KCIBCFLH_03503 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KCIBCFLH_03504 5.8e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KCIBCFLH_03505 8.2e-111 jag S single-stranded nucleic acid binding R3H
KCIBCFLH_03506 1.4e-128 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCIBCFLH_03507 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)