ORF_ID e_value Gene_name EC_number CAZy COGs Description
MGECLEDA_00001 5.8e-09 azoB GM NmrA-like family
MGECLEDA_00002 3.3e-163 azoB GM NmrA-like family
MGECLEDA_00003 5.4e-66 K Winged helix DNA-binding domain
MGECLEDA_00004 7e-71 spx4 1.20.4.1 P ArsC family
MGECLEDA_00005 6.3e-66 yeaO S Protein of unknown function, DUF488
MGECLEDA_00006 4e-53
MGECLEDA_00007 4.1e-214 mutY L A G-specific adenine glycosylase
MGECLEDA_00008 1.9e-62
MGECLEDA_00009 4.3e-86
MGECLEDA_00010 1.2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
MGECLEDA_00011 7e-56
MGECLEDA_00012 2.1e-14
MGECLEDA_00013 1.1e-115 GM NmrA-like family
MGECLEDA_00014 1.4e-80 elaA S GNAT family
MGECLEDA_00015 1.6e-158 EG EamA-like transporter family
MGECLEDA_00016 1.8e-119 S membrane
MGECLEDA_00017 6.8e-111 S VIT family
MGECLEDA_00018 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MGECLEDA_00019 0.0 copB 3.6.3.4 P P-type ATPase
MGECLEDA_00020 9.4e-74 copR K Copper transport repressor CopY TcrY
MGECLEDA_00021 7.4e-40
MGECLEDA_00022 7e-74 S COG NOG18757 non supervised orthologous group
MGECLEDA_00023 3.3e-248 lmrB EGP Major facilitator Superfamily
MGECLEDA_00024 3.4e-25
MGECLEDA_00025 1.1e-49
MGECLEDA_00026 9.4e-65 ycgX S Protein of unknown function (DUF1398)
MGECLEDA_00027 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
MGECLEDA_00028 5.9e-214 mdtG EGP Major facilitator Superfamily
MGECLEDA_00029 1.8e-181 D Alpha beta
MGECLEDA_00030 5.8e-77 M1-874 K Domain of unknown function (DUF1836)
MGECLEDA_00031 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MGECLEDA_00032 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
MGECLEDA_00033 2.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MGECLEDA_00034 3.8e-152 ywkB S Membrane transport protein
MGECLEDA_00035 5.2e-164 yvgN C Aldo keto reductase
MGECLEDA_00036 9.2e-133 thrE S Putative threonine/serine exporter
MGECLEDA_00037 2e-77 S Threonine/Serine exporter, ThrE
MGECLEDA_00038 5.2e-43 S Protein of unknown function (DUF1093)
MGECLEDA_00039 1.5e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MGECLEDA_00040 3e-90 ymdB S Macro domain protein
MGECLEDA_00041 9.9e-95 K transcriptional regulator
MGECLEDA_00042 5.5e-50 yvlA
MGECLEDA_00043 7.9e-161 ypuA S Protein of unknown function (DUF1002)
MGECLEDA_00044 0.0
MGECLEDA_00045 5.8e-186 S Bacterial protein of unknown function (DUF916)
MGECLEDA_00046 1.7e-129 S WxL domain surface cell wall-binding
MGECLEDA_00047 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
MGECLEDA_00048 3.5e-88 K Winged helix DNA-binding domain
MGECLEDA_00049 5.3e-116 luxT K Bacterial regulatory proteins, tetR family
MGECLEDA_00050 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MGECLEDA_00051 1.8e-27
MGECLEDA_00052 3.3e-285 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
MGECLEDA_00053 8.3e-71 mltD CBM50 M PFAM NLP P60 protein
MGECLEDA_00054 5.5e-53
MGECLEDA_00055 4.2e-62
MGECLEDA_00057 8.6e-13
MGECLEDA_00058 3.7e-65 XK27_09885 V VanZ like family
MGECLEDA_00059 2.2e-11 K Cro/C1-type HTH DNA-binding domain
MGECLEDA_00060 1.2e-106
MGECLEDA_00061 6.6e-53 S Uncharacterized protein conserved in bacteria (DUF2316)
MGECLEDA_00062 5.3e-160 4.1.1.46 S Amidohydrolase
MGECLEDA_00063 1.6e-100 K transcriptional regulator
MGECLEDA_00064 7.2e-183 yfeX P Peroxidase
MGECLEDA_00065 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MGECLEDA_00066 2.4e-127 ydcF S Gram-negative-bacterium-type cell wall biogenesis
MGECLEDA_00067 1.3e-179 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
MGECLEDA_00068 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
MGECLEDA_00069 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MGECLEDA_00070 1.5e-55 txlA O Thioredoxin-like domain
MGECLEDA_00071 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
MGECLEDA_00072 1.6e-18
MGECLEDA_00073 2.8e-94 dps P Belongs to the Dps family
MGECLEDA_00074 1.6e-32 copZ P Heavy-metal-associated domain
MGECLEDA_00075 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MGECLEDA_00076 0.0 pepO 3.4.24.71 O Peptidase family M13
MGECLEDA_00077 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MGECLEDA_00078 2.9e-262 nox C NADH oxidase
MGECLEDA_00079 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
MGECLEDA_00080 6.1e-164 S Cell surface protein
MGECLEDA_00081 1.5e-118 S WxL domain surface cell wall-binding
MGECLEDA_00082 2.3e-99 S WxL domain surface cell wall-binding
MGECLEDA_00083 4.6e-45
MGECLEDA_00084 5.4e-104 K Bacterial regulatory proteins, tetR family
MGECLEDA_00085 1.5e-49
MGECLEDA_00086 1.4e-248 S Putative metallopeptidase domain
MGECLEDA_00087 2.4e-220 3.1.3.1 S associated with various cellular activities
MGECLEDA_00088 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
MGECLEDA_00089 0.0 ubiB S ABC1 family
MGECLEDA_00090 6.9e-251 brnQ U Component of the transport system for branched-chain amino acids
MGECLEDA_00091 0.0 lacS G Transporter
MGECLEDA_00092 0.0 lacA 3.2.1.23 G -beta-galactosidase
MGECLEDA_00093 1.6e-188 lacR K Transcriptional regulator
MGECLEDA_00094 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MGECLEDA_00095 1.6e-230 mdtH P Sugar (and other) transporter
MGECLEDA_00096 3e-303 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MGECLEDA_00097 9.5e-231 EGP Major facilitator Superfamily
MGECLEDA_00098 2.8e-182 rhaR K helix_turn_helix, arabinose operon control protein
MGECLEDA_00099 2e-84 fic D Fic/DOC family
MGECLEDA_00100 1.6e-76 K Helix-turn-helix XRE-family like proteins
MGECLEDA_00101 2e-183 galR K Transcriptional regulator
MGECLEDA_00102 1.1e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MGECLEDA_00103 8.9e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MGECLEDA_00104 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MGECLEDA_00105 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MGECLEDA_00106 8.3e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MGECLEDA_00107 0.0 rafA 3.2.1.22 G alpha-galactosidase
MGECLEDA_00108 0.0 lacS G Transporter
MGECLEDA_00109 1.7e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MGECLEDA_00110 1.1e-173 galR K Transcriptional regulator
MGECLEDA_00111 1.8e-192 C Aldo keto reductase family protein
MGECLEDA_00112 2.4e-65 S pyridoxamine 5-phosphate
MGECLEDA_00113 0.0 1.3.5.4 C FAD binding domain
MGECLEDA_00114 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MGECLEDA_00115 8.7e-131 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MGECLEDA_00116 1.2e-214 ydiM G Transporter
MGECLEDA_00117 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MGECLEDA_00118 4.5e-163 K Transcriptional regulator, LysR family
MGECLEDA_00119 1.3e-210 ydiN G Major Facilitator Superfamily
MGECLEDA_00120 7.6e-64
MGECLEDA_00121 9.9e-154 estA S Putative esterase
MGECLEDA_00122 6.2e-134 K UTRA domain
MGECLEDA_00123 6.9e-248 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_00124 3.3e-164 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MGECLEDA_00125 4e-159 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
MGECLEDA_00126 1.1e-211 S Bacterial protein of unknown function (DUF871)
MGECLEDA_00127 1.6e-290 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MGECLEDA_00128 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
MGECLEDA_00129 4.8e-154 licT K CAT RNA binding domain
MGECLEDA_00130 0.0 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MGECLEDA_00131 3.2e-225 malY 4.4.1.8 E Aminotransferase class I and II
MGECLEDA_00132 4.5e-269 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
MGECLEDA_00133 6.7e-75 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MGECLEDA_00134 5.4e-78 ptsG 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MGECLEDA_00135 6.7e-148 yleF K Helix-turn-helix domain, rpiR family
MGECLEDA_00136 4.9e-203 sacX 2.7.1.193, 2.7.1.211 G phosphotransferase system
MGECLEDA_00137 2e-155 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MGECLEDA_00138 1.8e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MGECLEDA_00139 3.1e-294 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MGECLEDA_00140 3.6e-290 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MGECLEDA_00141 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
MGECLEDA_00142 1.4e-158 licT K CAT RNA binding domain
MGECLEDA_00143 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
MGECLEDA_00144 2.1e-174 K Transcriptional regulator, LacI family
MGECLEDA_00145 1.1e-242 G Major Facilitator
MGECLEDA_00146 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MGECLEDA_00148 9.9e-188 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MGECLEDA_00149 1.5e-144 yxeH S hydrolase
MGECLEDA_00150 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MGECLEDA_00151 2e-115 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MGECLEDA_00152 1.5e-126 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
MGECLEDA_00153 6.6e-172 G Phosphotransferase System
MGECLEDA_00154 8.6e-48 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
MGECLEDA_00155 4.5e-74 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MGECLEDA_00157 1.2e-237 manR K PRD domain
MGECLEDA_00158 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MGECLEDA_00159 1.9e-231 gatC G PTS system sugar-specific permease component
MGECLEDA_00160 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MGECLEDA_00161 1.3e-79 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MGECLEDA_00162 5.2e-123 K DeoR C terminal sensor domain
MGECLEDA_00163 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MGECLEDA_00164 2e-70 yueI S Protein of unknown function (DUF1694)
MGECLEDA_00165 9.6e-103 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
MGECLEDA_00166 7.8e-266 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MGECLEDA_00167 1e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MGECLEDA_00168 1.7e-306 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
MGECLEDA_00169 1.6e-255 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MGECLEDA_00170 1.4e-206 araR K Transcriptional regulator
MGECLEDA_00171 7.4e-136 K Helix-turn-helix domain, rpiR family
MGECLEDA_00172 2.4e-71 yueI S Protein of unknown function (DUF1694)
MGECLEDA_00173 1.3e-164 I alpha/beta hydrolase fold
MGECLEDA_00174 2e-160 I alpha/beta hydrolase fold
MGECLEDA_00175 2.6e-272 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MGECLEDA_00176 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MGECLEDA_00177 1.9e-135 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
MGECLEDA_00178 5.2e-156 nanK GK ROK family
MGECLEDA_00179 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MGECLEDA_00180 1.1e-121 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MGECLEDA_00181 4.9e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
MGECLEDA_00182 4.2e-70 S Pyrimidine dimer DNA glycosylase
MGECLEDA_00183 4.5e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
MGECLEDA_00184 3.6e-11
MGECLEDA_00185 9e-13 ytgB S Transglycosylase associated protein
MGECLEDA_00186 2.1e-290 katA 1.11.1.6 C Belongs to the catalase family
MGECLEDA_00187 1.9e-77 yneH 1.20.4.1 K ArsC family
MGECLEDA_00188 2.8e-134 K LytTr DNA-binding domain
MGECLEDA_00189 8.7e-160 2.7.13.3 T GHKL domain
MGECLEDA_00190 1.8e-12
MGECLEDA_00191 5.3e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
MGECLEDA_00192 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
MGECLEDA_00194 3e-201 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MGECLEDA_00195 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MGECLEDA_00196 8.7e-72 K Transcriptional regulator
MGECLEDA_00197 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MGECLEDA_00198 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MGECLEDA_00199 1.3e-174 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
MGECLEDA_00200 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
MGECLEDA_00201 2.5e-86 gutM K Glucitol operon activator protein (GutM)
MGECLEDA_00202 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
MGECLEDA_00203 1.5e-144 IQ NAD dependent epimerase/dehydratase family
MGECLEDA_00204 1.4e-45 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MGECLEDA_00205 1.6e-158 dcm 2.1.1.37 H Cytosine-specific methyltransferase
MGECLEDA_00206 4.8e-133 mutH L DNA mismatch repair enzyme MutH
MGECLEDA_00207 2.7e-160 rbsU U ribose uptake protein RbsU
MGECLEDA_00208 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MGECLEDA_00209 4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MGECLEDA_00210 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
MGECLEDA_00211 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MGECLEDA_00212 2.7e-79 T Universal stress protein family
MGECLEDA_00213 2.2e-99 padR K Virulence activator alpha C-term
MGECLEDA_00214 1.7e-104 padC Q Phenolic acid decarboxylase
MGECLEDA_00215 5.5e-144 tesE Q hydratase
MGECLEDA_00216 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
MGECLEDA_00217 1e-156 degV S DegV family
MGECLEDA_00218 2.4e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
MGECLEDA_00219 2.8e-254 pepC 3.4.22.40 E aminopeptidase
MGECLEDA_00221 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MGECLEDA_00222 3.8e-303
MGECLEDA_00224 3.6e-159 S Bacterial protein of unknown function (DUF916)
MGECLEDA_00225 6.9e-93 S Cell surface protein
MGECLEDA_00226 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MGECLEDA_00227 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MGECLEDA_00228 2.5e-130 jag S R3H domain protein
MGECLEDA_00229 9.3e-239 Q Imidazolonepropionase and related amidohydrolases
MGECLEDA_00230 2.7e-310 E ABC transporter, substratebinding protein
MGECLEDA_00231 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MGECLEDA_00232 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MGECLEDA_00233 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MGECLEDA_00234 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MGECLEDA_00235 5e-37 yaaA S S4 domain protein YaaA
MGECLEDA_00236 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MGECLEDA_00237 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MGECLEDA_00238 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MGECLEDA_00239 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
MGECLEDA_00240 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MGECLEDA_00241 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MGECLEDA_00242 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MGECLEDA_00243 1.4e-67 rplI J Binds to the 23S rRNA
MGECLEDA_00244 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MGECLEDA_00245 8.8e-226 yttB EGP Major facilitator Superfamily
MGECLEDA_00246 1e-142 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MGECLEDA_00247 5e-229 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MGECLEDA_00249 1.9e-276 E ABC transporter, substratebinding protein
MGECLEDA_00251 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MGECLEDA_00252 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MGECLEDA_00253 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
MGECLEDA_00254 6.2e-279 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
MGECLEDA_00255 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MGECLEDA_00256 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
MGECLEDA_00258 4.5e-143 S haloacid dehalogenase-like hydrolase
MGECLEDA_00259 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MGECLEDA_00260 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
MGECLEDA_00261 1.5e-77 S Pyridoxamine 5'-phosphate oxidase
MGECLEDA_00262 1.6e-31 cspA K Cold shock protein domain
MGECLEDA_00263 1.7e-37
MGECLEDA_00265 6.2e-131 K response regulator
MGECLEDA_00266 0.0 vicK 2.7.13.3 T Histidine kinase
MGECLEDA_00267 2e-244 yycH S YycH protein
MGECLEDA_00268 2.2e-151 yycI S YycH protein
MGECLEDA_00269 4.4e-157 vicX 3.1.26.11 S domain protein
MGECLEDA_00270 6.8e-173 htrA 3.4.21.107 O serine protease
MGECLEDA_00271 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MGECLEDA_00272 1.5e-95 K Bacterial regulatory proteins, tetR family
MGECLEDA_00273 5.8e-261 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
MGECLEDA_00274 6.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
MGECLEDA_00275 9.1e-121 pnb C nitroreductase
MGECLEDA_00276 2.6e-64 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MGECLEDA_00277 2e-115 S Elongation factor G-binding protein, N-terminal
MGECLEDA_00278 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
MGECLEDA_00279 1.6e-258 P Sodium:sulfate symporter transmembrane region
MGECLEDA_00280 5.7e-158 K LysR family
MGECLEDA_00281 1e-72 C FMN binding
MGECLEDA_00282 9.3e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MGECLEDA_00283 2.3e-164 ptlF S KR domain
MGECLEDA_00284 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
MGECLEDA_00285 1.3e-122 drgA C Nitroreductase family
MGECLEDA_00286 1.3e-290 QT PucR C-terminal helix-turn-helix domain
MGECLEDA_00287 5.5e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MGECLEDA_00288 1.1e-194 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MGECLEDA_00289 7.4e-250 yjjP S Putative threonine/serine exporter
MGECLEDA_00290 1.7e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
MGECLEDA_00291 1.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
MGECLEDA_00292 2.9e-81 6.3.3.2 S ASCH
MGECLEDA_00293 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
MGECLEDA_00294 5.5e-172 yobV1 K WYL domain
MGECLEDA_00295 1e-116 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MGECLEDA_00296 0.0 tetP J elongation factor G
MGECLEDA_00297 8.2e-39 S Protein of unknown function
MGECLEDA_00298 2.7e-61 S Protein of unknown function
MGECLEDA_00299 3.6e-152 EG EamA-like transporter family
MGECLEDA_00300 3.6e-93 MA20_25245 K FR47-like protein
MGECLEDA_00301 4.4e-126 hchA S DJ-1/PfpI family
MGECLEDA_00302 5.4e-181 1.1.1.1 C nadph quinone reductase
MGECLEDA_00303 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
MGECLEDA_00304 3.9e-235 mepA V MATE efflux family protein
MGECLEDA_00305 1e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
MGECLEDA_00306 1e-139 S Belongs to the UPF0246 family
MGECLEDA_00307 6e-76
MGECLEDA_00308 4.6e-311 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
MGECLEDA_00309 1.2e-140
MGECLEDA_00311 7e-110 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
MGECLEDA_00312 4.8e-40
MGECLEDA_00313 1.1e-127 cbiO P ABC transporter
MGECLEDA_00314 2.6e-149 P Cobalt transport protein
MGECLEDA_00315 4.8e-182 nikMN P PDGLE domain
MGECLEDA_00316 4.2e-121 K Crp-like helix-turn-helix domain
MGECLEDA_00317 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
MGECLEDA_00318 2.4e-125 larB S AIR carboxylase
MGECLEDA_00319 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MGECLEDA_00320 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
MGECLEDA_00321 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MGECLEDA_00322 2.8e-151 larE S NAD synthase
MGECLEDA_00323 8.7e-176 1.6.5.5 C Zinc-binding dehydrogenase
MGECLEDA_00325 2.2e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MGECLEDA_00326 9.1e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MGECLEDA_00327 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MGECLEDA_00328 2.1e-203 cytX U Belongs to the purine-cytosine permease (2.A.39) family
MGECLEDA_00329 5.1e-136 S peptidase C26
MGECLEDA_00330 8e-304 L HIRAN domain
MGECLEDA_00331 9.9e-85 F NUDIX domain
MGECLEDA_00332 2.6e-250 yifK E Amino acid permease
MGECLEDA_00333 2e-121
MGECLEDA_00334 4.3e-149 ydjP I Alpha/beta hydrolase family
MGECLEDA_00335 0.0 pacL1 P P-type ATPase
MGECLEDA_00336 1.6e-28 KT PspC domain
MGECLEDA_00337 1.5e-109 S NADPH-dependent FMN reductase
MGECLEDA_00338 1.9e-75 papX3 K Transcriptional regulator
MGECLEDA_00339 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
MGECLEDA_00340 1.1e-80 S Protein of unknown function (DUF3021)
MGECLEDA_00341 4.7e-227 mdtG EGP Major facilitator Superfamily
MGECLEDA_00342 1.9e-50 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
MGECLEDA_00343 1.5e-214 yeaN P Transporter, major facilitator family protein
MGECLEDA_00345 3.4e-160 S reductase
MGECLEDA_00346 1.2e-165 1.1.1.65 C Aldo keto reductase
MGECLEDA_00347 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
MGECLEDA_00348 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
MGECLEDA_00349 5e-52
MGECLEDA_00350 7.5e-259
MGECLEDA_00351 2.6e-208 C Oxidoreductase
MGECLEDA_00352 4.9e-151 cbiQ P cobalt transport
MGECLEDA_00353 0.0 ykoD P ABC transporter, ATP-binding protein
MGECLEDA_00354 2.5e-98 S UPF0397 protein
MGECLEDA_00356 1.6e-129 K UbiC transcription regulator-associated domain protein
MGECLEDA_00357 8.3e-54 K Transcriptional regulator PadR-like family
MGECLEDA_00358 4.6e-143
MGECLEDA_00359 2.2e-148
MGECLEDA_00360 9.1e-89
MGECLEDA_00361 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MGECLEDA_00362 2.2e-168 yjjC V ABC transporter
MGECLEDA_00363 7.2e-300 M Exporter of polyketide antibiotics
MGECLEDA_00364 1.6e-117 K Transcriptional regulator
MGECLEDA_00365 2.1e-277 C Electron transfer flavoprotein FAD-binding domain
MGECLEDA_00366 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
MGECLEDA_00368 1.1e-92 K Bacterial regulatory proteins, tetR family
MGECLEDA_00369 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MGECLEDA_00370 5e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MGECLEDA_00371 1.9e-101 dhaL 2.7.1.121 S Dak2
MGECLEDA_00372 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
MGECLEDA_00373 8.6e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MGECLEDA_00374 1e-190 malR K Transcriptional regulator, LacI family
MGECLEDA_00375 2e-180 yvdE K helix_turn _helix lactose operon repressor
MGECLEDA_00376 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
MGECLEDA_00377 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
MGECLEDA_00378 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
MGECLEDA_00379 1.4e-161 malD P ABC transporter permease
MGECLEDA_00380 5.3e-150 malA S maltodextrose utilization protein MalA
MGECLEDA_00381 5.5e-258 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
MGECLEDA_00382 4e-209 msmK P Belongs to the ABC transporter superfamily
MGECLEDA_00383 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MGECLEDA_00384 0.0 3.2.1.96 G Glycosyl hydrolase family 85
MGECLEDA_00385 2e-45 ygbF S Sugar efflux transporter for intercellular exchange
MGECLEDA_00386 9.2e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MGECLEDA_00387 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
MGECLEDA_00388 1.4e-305 scrB 3.2.1.26 GH32 G invertase
MGECLEDA_00389 9.1e-173 scrR K Transcriptional regulator, LacI family
MGECLEDA_00390 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MGECLEDA_00391 1.3e-165 3.5.1.10 C nadph quinone reductase
MGECLEDA_00392 1.1e-217 nhaC C Na H antiporter NhaC
MGECLEDA_00393 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MGECLEDA_00394 7.7e-166 mleR K LysR substrate binding domain
MGECLEDA_00395 2.5e-200 3.6.4.13 M domain protein
MGECLEDA_00396 8.3e-136 3.6.4.13 M domain protein
MGECLEDA_00398 2.1e-157 hipB K Helix-turn-helix
MGECLEDA_00399 0.0 oppA E ABC transporter, substratebinding protein
MGECLEDA_00400 3.5e-310 oppA E ABC transporter, substratebinding protein
MGECLEDA_00401 1e-78 yiaC K Acetyltransferase (GNAT) domain
MGECLEDA_00402 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MGECLEDA_00403 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MGECLEDA_00404 3.3e-112 pgm1 G phosphoglycerate mutase
MGECLEDA_00405 1e-179 yghZ C Aldo keto reductase family protein
MGECLEDA_00406 4.9e-34
MGECLEDA_00407 1.3e-60 S Domain of unknown function (DU1801)
MGECLEDA_00408 3.8e-162 FbpA K Domain of unknown function (DUF814)
MGECLEDA_00409 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MGECLEDA_00411 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MGECLEDA_00412 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MGECLEDA_00413 1.1e-257 S ATPases associated with a variety of cellular activities
MGECLEDA_00414 4.8e-62
MGECLEDA_00415 1.5e-115 P cobalt transport
MGECLEDA_00416 2e-258 P ABC transporter
MGECLEDA_00417 3.1e-101 S ABC transporter permease
MGECLEDA_00418 6.9e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MGECLEDA_00419 4.1e-158 dkgB S reductase
MGECLEDA_00420 4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MGECLEDA_00421 5.1e-69
MGECLEDA_00422 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MGECLEDA_00423 4.5e-174 P Major Facilitator Superfamily
MGECLEDA_00424 1.3e-223 1.3.5.4 C FAD dependent oxidoreductase
MGECLEDA_00425 4.8e-99 K Helix-turn-helix domain
MGECLEDA_00426 2.6e-277 pipD E Dipeptidase
MGECLEDA_00427 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MGECLEDA_00428 0.0 mtlR K Mga helix-turn-helix domain
MGECLEDA_00429 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_00430 2.8e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MGECLEDA_00431 3.5e-73
MGECLEDA_00432 2e-55 trxA1 O Belongs to the thioredoxin family
MGECLEDA_00433 2.2e-46
MGECLEDA_00434 2.5e-95
MGECLEDA_00435 1.7e-61
MGECLEDA_00436 2.5e-80 ndk 2.7.4.6 F Belongs to the NDK family
MGECLEDA_00437 7.6e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
MGECLEDA_00438 5.4e-98 yieF S NADPH-dependent FMN reductase
MGECLEDA_00439 3.6e-123 K helix_turn_helix gluconate operon transcriptional repressor
MGECLEDA_00440 8.8e-229 pts3C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_00441 4.7e-39
MGECLEDA_00442 2.2e-212 S Bacterial protein of unknown function (DUF871)
MGECLEDA_00443 3e-212 dho 3.5.2.3 S Amidohydrolase family
MGECLEDA_00444 5.2e-201 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
MGECLEDA_00445 4.6e-129 4.1.2.14 S KDGP aldolase
MGECLEDA_00446 1.9e-189 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
MGECLEDA_00447 1.2e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
MGECLEDA_00448 3.7e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MGECLEDA_00449 5.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MGECLEDA_00450 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
MGECLEDA_00451 9.7e-138 pnuC H nicotinamide mononucleotide transporter
MGECLEDA_00452 7.3e-43 S Protein of unknown function (DUF2089)
MGECLEDA_00453 1.7e-42
MGECLEDA_00454 3.5e-129 treR K UTRA
MGECLEDA_00455 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MGECLEDA_00456 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
MGECLEDA_00457 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
MGECLEDA_00458 2.4e-144
MGECLEDA_00459 6.3e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MGECLEDA_00460 1.6e-70
MGECLEDA_00461 1.8e-72 K Transcriptional regulator
MGECLEDA_00462 4.3e-121 K Bacterial regulatory proteins, tetR family
MGECLEDA_00463 6.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
MGECLEDA_00464 5.5e-118
MGECLEDA_00465 5.2e-42
MGECLEDA_00466 1e-40
MGECLEDA_00467 9.7e-253 ydiC1 EGP Major facilitator Superfamily
MGECLEDA_00468 2.1e-64 K helix_turn_helix, mercury resistance
MGECLEDA_00469 2.3e-251 T PhoQ Sensor
MGECLEDA_00470 3.4e-129 K Transcriptional regulatory protein, C terminal
MGECLEDA_00471 1.8e-49
MGECLEDA_00472 1.3e-128 yidA K Helix-turn-helix domain, rpiR family
MGECLEDA_00473 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_00474 9.9e-57
MGECLEDA_00475 2.1e-41
MGECLEDA_00476 1.4e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MGECLEDA_00477 2e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
MGECLEDA_00478 1.3e-47
MGECLEDA_00479 2.7e-123 2.7.6.5 S RelA SpoT domain protein
MGECLEDA_00480 3.1e-104 K transcriptional regulator
MGECLEDA_00481 0.0 ydgH S MMPL family
MGECLEDA_00482 1e-107 tag 3.2.2.20 L glycosylase
MGECLEDA_00483 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
MGECLEDA_00484 1.8e-185 yclI V MacB-like periplasmic core domain
MGECLEDA_00485 7.1e-121 yclH V ABC transporter
MGECLEDA_00486 2.5e-114 V CAAX protease self-immunity
MGECLEDA_00487 2.5e-99 S CAAX protease self-immunity
MGECLEDA_00488 1.7e-52 M Lysin motif
MGECLEDA_00489 1.2e-29 lytE M LysM domain protein
MGECLEDA_00490 7.4e-67 gcvH E Glycine cleavage H-protein
MGECLEDA_00491 2.8e-176 sepS16B
MGECLEDA_00492 1.8e-130
MGECLEDA_00493 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
MGECLEDA_00494 6.8e-57
MGECLEDA_00495 1.2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MGECLEDA_00496 6.5e-78 elaA S GNAT family
MGECLEDA_00497 1.7e-75 K Transcriptional regulator
MGECLEDA_00498 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
MGECLEDA_00499 3.1e-38
MGECLEDA_00500 2.5e-08 S Motility quorum-sensing regulator, toxin of MqsA
MGECLEDA_00501 1.7e-30
MGECLEDA_00502 7.1e-21 U Preprotein translocase subunit SecB
MGECLEDA_00503 4e-206 potD P ABC transporter
MGECLEDA_00504 3.4e-141 potC P ABC transporter permease
MGECLEDA_00505 2e-149 potB P ABC transporter permease
MGECLEDA_00506 2.6e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MGECLEDA_00507 5e-96 puuR K Cupin domain
MGECLEDA_00508 1.1e-83 6.3.3.2 S ASCH
MGECLEDA_00509 1e-84 K GNAT family
MGECLEDA_00510 8e-91 K acetyltransferase
MGECLEDA_00511 8.1e-22
MGECLEDA_00512 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
MGECLEDA_00513 2e-163 ytrB V ABC transporter
MGECLEDA_00514 3.2e-189
MGECLEDA_00515 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
MGECLEDA_00516 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MGECLEDA_00518 2.3e-240 xylP1 G MFS/sugar transport protein
MGECLEDA_00519 3e-122 qmcA O prohibitin homologues
MGECLEDA_00520 3e-30
MGECLEDA_00521 1.7e-281 pipD E Dipeptidase
MGECLEDA_00522 3e-40
MGECLEDA_00523 6.8e-96 bioY S BioY family
MGECLEDA_00524 1.4e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MGECLEDA_00525 2.8e-60 S CHY zinc finger
MGECLEDA_00526 2.2e-111 metQ P NLPA lipoprotein
MGECLEDA_00527 8.7e-126 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MGECLEDA_00528 1.1e-86 metI U Binding-protein-dependent transport system inner membrane component
MGECLEDA_00529 7.7e-148 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MGECLEDA_00530 2.1e-224 mtnE 2.6.1.83 E Aminotransferase
MGECLEDA_00531 1.4e-217
MGECLEDA_00532 3.5e-154 tagG U Transport permease protein
MGECLEDA_00533 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MGECLEDA_00534 8.4e-44
MGECLEDA_00535 2.4e-90 K Transcriptional regulator PadR-like family
MGECLEDA_00536 2.1e-258 P Major Facilitator Superfamily
MGECLEDA_00537 1.2e-241 amtB P ammonium transporter
MGECLEDA_00538 2e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MGECLEDA_00539 3.7e-44
MGECLEDA_00540 6.3e-102 zmp1 O Zinc-dependent metalloprotease
MGECLEDA_00541 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MGECLEDA_00542 1.5e-310 mco Q Multicopper oxidase
MGECLEDA_00543 1.1e-54 ypaA S Protein of unknown function (DUF1304)
MGECLEDA_00544 6.4e-40 yxkA S Phosphatidylethanolamine-binding protein
MGECLEDA_00545 3.1e-113 flhF N Uncharacterized conserved protein (DUF2075)
MGECLEDA_00546 1.6e-82 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
MGECLEDA_00547 9.3e-80
MGECLEDA_00548 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MGECLEDA_00549 1.7e-173 rihC 3.2.2.1 F Nucleoside
MGECLEDA_00550 3.3e-161 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
MGECLEDA_00551 1.1e-77 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
MGECLEDA_00552 1.8e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MGECLEDA_00553 3.8e-179 proV E ABC transporter, ATP-binding protein
MGECLEDA_00554 7.5e-255 gshR 1.8.1.7 C Glutathione reductase
MGECLEDA_00555 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MGECLEDA_00556 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
MGECLEDA_00557 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MGECLEDA_00558 0.0 M domain protein
MGECLEDA_00559 2.2e-47 1.1.98.6, 3.6.3.14, 3.6.3.15, 4.1.1.35 L Participates in initiation and elongation during chromosome replication
MGECLEDA_00560 2.4e-51
MGECLEDA_00561 9.2e-127
MGECLEDA_00562 2.8e-28
MGECLEDA_00563 1.2e-64
MGECLEDA_00564 5.6e-68 S Immunity protein 63
MGECLEDA_00565 2.4e-38
MGECLEDA_00566 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MGECLEDA_00567 4.8e-197 uhpT EGP Major facilitator Superfamily
MGECLEDA_00568 6.9e-147 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
MGECLEDA_00569 3.3e-166 K Transcriptional regulator
MGECLEDA_00570 1.4e-150 S hydrolase
MGECLEDA_00571 3.5e-255 brnQ U Component of the transport system for branched-chain amino acids
MGECLEDA_00572 8e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MGECLEDA_00575 3.4e-115
MGECLEDA_00577 3.1e-99 2.7.13.3 T GHKL domain
MGECLEDA_00578 4.5e-132 plnD K LytTr DNA-binding domain
MGECLEDA_00579 9.1e-128 S CAAX protease self-immunity
MGECLEDA_00580 2.4e-22 plnF
MGECLEDA_00581 6.7e-23
MGECLEDA_00582 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MGECLEDA_00583 1.7e-241 mesE M Transport protein ComB
MGECLEDA_00584 4.1e-20 sagE V CAAX protease self-immunity
MGECLEDA_00585 2.4e-69 S CAAX protease self-immunity
MGECLEDA_00586 1.1e-118 ypbD S CAAX protease self-immunity
MGECLEDA_00587 8.1e-112 V CAAX protease self-immunity
MGECLEDA_00588 6.8e-99 S CAAX protease self-immunity
MGECLEDA_00589 1.8e-30
MGECLEDA_00590 0.0 helD 3.6.4.12 L DNA helicase
MGECLEDA_00591 1.2e-143 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MGECLEDA_00592 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MGECLEDA_00593 9e-130 K UbiC transcription regulator-associated domain protein
MGECLEDA_00594 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_00595 3.9e-24
MGECLEDA_00596 1.4e-74 S Domain of unknown function (DUF3284)
MGECLEDA_00597 2.6e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_00598 7.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MGECLEDA_00599 6.6e-162 GK ROK family
MGECLEDA_00600 4.1e-133 K Helix-turn-helix domain, rpiR family
MGECLEDA_00601 1.4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MGECLEDA_00602 2.9e-207
MGECLEDA_00603 7.9e-151 S Psort location Cytoplasmic, score
MGECLEDA_00604 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MGECLEDA_00605 2.9e-227 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MGECLEDA_00606 3.1e-178
MGECLEDA_00607 3.9e-133 cobB K SIR2 family
MGECLEDA_00608 2e-160 yunF F Protein of unknown function DUF72
MGECLEDA_00609 1.8e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
MGECLEDA_00610 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MGECLEDA_00611 9.2e-212 bcr1 EGP Major facilitator Superfamily
MGECLEDA_00612 5.7e-146 tatD L hydrolase, TatD family
MGECLEDA_00613 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MGECLEDA_00614 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MGECLEDA_00615 3.2e-37 veg S Biofilm formation stimulator VEG
MGECLEDA_00616 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MGECLEDA_00617 8.8e-31 S Prolyl oligopeptidase family
MGECLEDA_00618 1.1e-118 S Prolyl oligopeptidase family
MGECLEDA_00619 9.8e-129 fhuC 3.6.3.35 P ABC transporter
MGECLEDA_00620 9.2e-131 znuB U ABC 3 transport family
MGECLEDA_00621 6.7e-12 T Pre-toxin TG
MGECLEDA_00622 2.9e-43 ankB S ankyrin repeats
MGECLEDA_00623 6e-31
MGECLEDA_00624 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MGECLEDA_00625 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MGECLEDA_00626 3.4e-149 bla1 3.5.2.6 V Beta-lactamase enzyme family
MGECLEDA_00627 4.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MGECLEDA_00628 2.5e-181 S DUF218 domain
MGECLEDA_00629 4.1e-125
MGECLEDA_00630 1.7e-148 yxeH S hydrolase
MGECLEDA_00631 9e-264 ywfO S HD domain protein
MGECLEDA_00632 4.8e-154 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
MGECLEDA_00633 1.4e-77 ywiB S Domain of unknown function (DUF1934)
MGECLEDA_00634 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MGECLEDA_00635 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MGECLEDA_00636 1.1e-244 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MGECLEDA_00637 3.1e-229 tdcC E amino acid
MGECLEDA_00638 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MGECLEDA_00639 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MGECLEDA_00640 6.4e-131 S YheO-like PAS domain
MGECLEDA_00641 2.5e-26
MGECLEDA_00642 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MGECLEDA_00643 3e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MGECLEDA_00644 7.8e-41 rpmE2 J Ribosomal protein L31
MGECLEDA_00645 3.6e-213 J translation release factor activity
MGECLEDA_00646 3.5e-126 srtA 3.4.22.70 M sortase family
MGECLEDA_00647 1.7e-91 lemA S LemA family
MGECLEDA_00648 6e-139 htpX O Belongs to the peptidase M48B family
MGECLEDA_00649 2e-146
MGECLEDA_00650 5.6e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MGECLEDA_00651 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MGECLEDA_00652 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MGECLEDA_00653 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MGECLEDA_00654 2.3e-63 ndoA L Toxic component of a toxin-antitoxin (TA) module
MGECLEDA_00655 0.0 kup P Transport of potassium into the cell
MGECLEDA_00656 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MGECLEDA_00657 1.7e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MGECLEDA_00658 3.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MGECLEDA_00659 3.4e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MGECLEDA_00660 1e-15 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
MGECLEDA_00661 9.6e-104 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
MGECLEDA_00662 4e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine
MGECLEDA_00663 4.5e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MGECLEDA_00664 4.1e-84 S QueT transporter
MGECLEDA_00665 2.1e-114 S (CBS) domain
MGECLEDA_00666 4.2e-264 S Putative peptidoglycan binding domain
MGECLEDA_00667 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MGECLEDA_00668 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MGECLEDA_00669 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MGECLEDA_00670 3.3e-289 yabM S Polysaccharide biosynthesis protein
MGECLEDA_00671 2.2e-42 yabO J S4 domain protein
MGECLEDA_00673 1.1e-63 divIC D Septum formation initiator
MGECLEDA_00674 3.1e-74 yabR J RNA binding
MGECLEDA_00675 3.2e-253 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MGECLEDA_00676 8.5e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MGECLEDA_00677 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MGECLEDA_00678 4.5e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MGECLEDA_00679 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MGECLEDA_00680 1.9e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MGECLEDA_00683 3e-252 dtpT U amino acid peptide transporter
MGECLEDA_00684 1.3e-150 yjjH S Calcineurin-like phosphoesterase
MGECLEDA_00688 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
MGECLEDA_00689 2.5e-53 S Cupin domain
MGECLEDA_00690 1.1e-166 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
MGECLEDA_00691 2.2e-191 ybiR P Citrate transporter
MGECLEDA_00692 3.7e-151 pnuC H nicotinamide mononucleotide transporter
MGECLEDA_00693 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MGECLEDA_00694 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MGECLEDA_00695 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
MGECLEDA_00696 1.2e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MGECLEDA_00697 1.5e-288 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MGECLEDA_00698 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MGECLEDA_00699 0.0 pacL 3.6.3.8 P P-type ATPase
MGECLEDA_00700 8.9e-72
MGECLEDA_00701 0.0 yhgF K Tex-like protein N-terminal domain protein
MGECLEDA_00702 2.2e-81 ydcK S Belongs to the SprT family
MGECLEDA_00703 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MGECLEDA_00704 1.1e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MGECLEDA_00706 9.3e-155 G Peptidase_C39 like family
MGECLEDA_00707 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MGECLEDA_00708 3.4e-133 manY G PTS system
MGECLEDA_00709 3.6e-171 manN G system, mannose fructose sorbose family IID component
MGECLEDA_00710 4.7e-64 S Domain of unknown function (DUF956)
MGECLEDA_00711 0.0 levR K Sigma-54 interaction domain
MGECLEDA_00712 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
MGECLEDA_00713 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
MGECLEDA_00714 2.3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MGECLEDA_00715 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
MGECLEDA_00716 1.2e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
MGECLEDA_00717 3.7e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MGECLEDA_00718 1.8e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
MGECLEDA_00719 2.4e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MGECLEDA_00720 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MGECLEDA_00721 1.7e-177 EG EamA-like transporter family
MGECLEDA_00722 4.7e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MGECLEDA_00723 1.5e-112 zmp2 O Zinc-dependent metalloprotease
MGECLEDA_00724 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
MGECLEDA_00725 3.5e-123 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MGECLEDA_00726 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
MGECLEDA_00727 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MGECLEDA_00728 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MGECLEDA_00729 3.7e-205 yacL S domain protein
MGECLEDA_00730 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MGECLEDA_00731 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MGECLEDA_00732 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MGECLEDA_00733 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MGECLEDA_00734 5.4e-98 yacP S YacP-like NYN domain
MGECLEDA_00735 1.5e-100 sigH K Sigma-70 region 2
MGECLEDA_00736 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MGECLEDA_00737 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MGECLEDA_00738 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
MGECLEDA_00739 1.1e-158 S Alpha/beta hydrolase of unknown function (DUF915)
MGECLEDA_00740 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MGECLEDA_00741 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MGECLEDA_00742 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MGECLEDA_00743 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MGECLEDA_00744 5.5e-178 F DNA/RNA non-specific endonuclease
MGECLEDA_00745 9e-39 L nuclease
MGECLEDA_00746 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MGECLEDA_00747 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
MGECLEDA_00748 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MGECLEDA_00749 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MGECLEDA_00750 6.5e-37 nrdH O Glutaredoxin
MGECLEDA_00751 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
MGECLEDA_00752 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MGECLEDA_00753 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MGECLEDA_00754 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MGECLEDA_00755 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MGECLEDA_00756 2.2e-38 yaaL S Protein of unknown function (DUF2508)
MGECLEDA_00757 7.3e-191 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MGECLEDA_00758 3e-09 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MGECLEDA_00759 1.1e-50 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MGECLEDA_00760 1.1e-40 ulaB_1 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
MGECLEDA_00761 2e-220 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MGECLEDA_00762 2.5e-99 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MGECLEDA_00763 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MGECLEDA_00764 2.4e-53 yaaQ S Cyclic-di-AMP receptor
MGECLEDA_00765 3.3e-186 holB 2.7.7.7 L DNA polymerase III
MGECLEDA_00766 1e-57 yabA L Involved in initiation control of chromosome replication
MGECLEDA_00767 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MGECLEDA_00768 2.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
MGECLEDA_00769 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MGECLEDA_00770 1.2e-210 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
MGECLEDA_00771 3.2e-144 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
MGECLEDA_00772 5.9e-144 phnE1 3.6.1.63 U ABC transporter permease
MGECLEDA_00773 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
MGECLEDA_00774 2.8e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MGECLEDA_00775 5.1e-190 phnD P Phosphonate ABC transporter
MGECLEDA_00776 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MGECLEDA_00777 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MGECLEDA_00778 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MGECLEDA_00779 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MGECLEDA_00780 1.4e-305 uup S ABC transporter, ATP-binding protein
MGECLEDA_00781 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MGECLEDA_00782 6.1e-109 ydiL S CAAX protease self-immunity
MGECLEDA_00783 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MGECLEDA_00784 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MGECLEDA_00785 0.0 ydaO E amino acid
MGECLEDA_00786 3.5e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
MGECLEDA_00787 4.3e-145 pstS P Phosphate
MGECLEDA_00788 6.3e-114 yvyE 3.4.13.9 S YigZ family
MGECLEDA_00789 4.3e-258 comFA L Helicase C-terminal domain protein
MGECLEDA_00790 7.5e-126 comFC S Competence protein
MGECLEDA_00791 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MGECLEDA_00792 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MGECLEDA_00793 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MGECLEDA_00794 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
MGECLEDA_00795 1.5e-132 K response regulator
MGECLEDA_00796 3.5e-250 phoR 2.7.13.3 T Histidine kinase
MGECLEDA_00797 1.1e-150 pstS P Phosphate
MGECLEDA_00798 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
MGECLEDA_00799 1.5e-155 pstA P Phosphate transport system permease protein PstA
MGECLEDA_00800 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MGECLEDA_00801 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MGECLEDA_00802 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
MGECLEDA_00803 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
MGECLEDA_00804 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MGECLEDA_00805 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MGECLEDA_00806 2.3e-164 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MGECLEDA_00807 1.9e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MGECLEDA_00808 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MGECLEDA_00809 1.9e-124 yliE T Putative diguanylate phosphodiesterase
MGECLEDA_00810 1.4e-270 nox C NADH oxidase
MGECLEDA_00811 4.8e-162 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
MGECLEDA_00812 1.2e-245
MGECLEDA_00813 1.3e-205 S Protein conserved in bacteria
MGECLEDA_00814 4.4e-217 ydaM M Glycosyl transferase family group 2
MGECLEDA_00815 0.0 ydaN S Bacterial cellulose synthase subunit
MGECLEDA_00816 1e-132 2.7.7.65 T diguanylate cyclase activity
MGECLEDA_00817 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MGECLEDA_00818 2e-109 yviA S Protein of unknown function (DUF421)
MGECLEDA_00819 1.1e-61 S Protein of unknown function (DUF3290)
MGECLEDA_00820 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MGECLEDA_00821 3.3e-132 yliE T Putative diguanylate phosphodiesterase
MGECLEDA_00822 2.3e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MGECLEDA_00823 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MGECLEDA_00824 2.4e-207 norA EGP Major facilitator Superfamily
MGECLEDA_00825 1.2e-117 yfbR S HD containing hydrolase-like enzyme
MGECLEDA_00826 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MGECLEDA_00827 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MGECLEDA_00828 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MGECLEDA_00829 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MGECLEDA_00830 6.1e-263 argH 4.3.2.1 E argininosuccinate lyase
MGECLEDA_00831 9.3e-87 S Short repeat of unknown function (DUF308)
MGECLEDA_00832 1.1e-161 rapZ S Displays ATPase and GTPase activities
MGECLEDA_00833 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MGECLEDA_00834 3.7e-168 whiA K May be required for sporulation
MGECLEDA_00835 2.6e-305 oppA E ABC transporter, substratebinding protein
MGECLEDA_00836 3.9e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MGECLEDA_00837 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MGECLEDA_00839 4.2e-245 rpoN K Sigma-54 factor, core binding domain
MGECLEDA_00840 7.3e-189 cggR K Putative sugar-binding domain
MGECLEDA_00841 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MGECLEDA_00842 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MGECLEDA_00843 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MGECLEDA_00844 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MGECLEDA_00845 1.3e-133
MGECLEDA_00846 6.6e-295 clcA P chloride
MGECLEDA_00847 1.2e-30 secG U Preprotein translocase
MGECLEDA_00848 1.3e-139 est 3.1.1.1 S Serine aminopeptidase, S33
MGECLEDA_00849 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MGECLEDA_00850 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MGECLEDA_00851 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
MGECLEDA_00852 1.5e-256 glnP P ABC transporter
MGECLEDA_00853 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MGECLEDA_00854 6.1e-105 yxjI
MGECLEDA_00855 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
MGECLEDA_00856 6.3e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MGECLEDA_00857 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MGECLEDA_00858 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MGECLEDA_00859 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
MGECLEDA_00860 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
MGECLEDA_00861 1.6e-153 xth 3.1.11.2 L exodeoxyribonuclease III
MGECLEDA_00862 2.1e-160 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MGECLEDA_00863 6.2e-168 murB 1.3.1.98 M Cell wall formation
MGECLEDA_00864 0.0 yjcE P Sodium proton antiporter
MGECLEDA_00865 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
MGECLEDA_00866 7.1e-121 S Protein of unknown function (DUF1361)
MGECLEDA_00867 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MGECLEDA_00868 1.6e-129 ybbR S YbbR-like protein
MGECLEDA_00869 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MGECLEDA_00870 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MGECLEDA_00871 4.9e-122 yliE T EAL domain
MGECLEDA_00872 2.8e-143 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
MGECLEDA_00873 2e-103 K Bacterial regulatory proteins, tetR family
MGECLEDA_00874 6.9e-124 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MGECLEDA_00875 2.1e-73 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MGECLEDA_00876 1.5e-52
MGECLEDA_00877 3e-72
MGECLEDA_00878 3e-131 1.5.1.39 C nitroreductase
MGECLEDA_00879 1.5e-150 G Transmembrane secretion effector
MGECLEDA_00880 7e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MGECLEDA_00881 2.7e-143
MGECLEDA_00883 1.9e-71 spxA 1.20.4.1 P ArsC family
MGECLEDA_00884 1.5e-33
MGECLEDA_00885 1.1e-89 V VanZ like family
MGECLEDA_00886 2.3e-241 EGP Major facilitator Superfamily
MGECLEDA_00887 9.4e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MGECLEDA_00888 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MGECLEDA_00889 2e-288 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MGECLEDA_00890 5e-153 licD M LicD family
MGECLEDA_00891 1.3e-82 K Transcriptional regulator
MGECLEDA_00892 1.5e-19
MGECLEDA_00893 1.2e-225 pbuG S permease
MGECLEDA_00894 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MGECLEDA_00895 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MGECLEDA_00896 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MGECLEDA_00897 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MGECLEDA_00898 2e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MGECLEDA_00899 0.0 oatA I Acyltransferase
MGECLEDA_00900 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MGECLEDA_00901 5e-69 O OsmC-like protein
MGECLEDA_00902 7.6e-46
MGECLEDA_00903 1.1e-251 yfnA E Amino Acid
MGECLEDA_00904 2.5e-88
MGECLEDA_00905 9.9e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MGECLEDA_00906 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MGECLEDA_00907 1.8e-19
MGECLEDA_00908 6.3e-105 gmk2 2.7.4.8 F Guanylate kinase
MGECLEDA_00909 1.3e-81 zur P Belongs to the Fur family
MGECLEDA_00910 7.1e-12 3.2.1.14 GH18
MGECLEDA_00911 4.9e-148
MGECLEDA_00912 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MGECLEDA_00913 6e-211 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MGECLEDA_00914 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MGECLEDA_00915 3.6e-41
MGECLEDA_00917 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MGECLEDA_00918 7.8e-149 glnH ET ABC transporter substrate-binding protein
MGECLEDA_00919 1.6e-109 gluC P ABC transporter permease
MGECLEDA_00920 4e-108 glnP P ABC transporter permease
MGECLEDA_00921 3.9e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MGECLEDA_00922 4.7e-154 K CAT RNA binding domain
MGECLEDA_00923 9.7e-256 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
MGECLEDA_00924 2.4e-141 G YdjC-like protein
MGECLEDA_00925 2.4e-245 steT E amino acid
MGECLEDA_00926 4.8e-73 mgrA K helix_turn_helix multiple antibiotic resistance protein
MGECLEDA_00927 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
MGECLEDA_00928 2e-71 K MarR family
MGECLEDA_00929 4.9e-210 EGP Major facilitator Superfamily
MGECLEDA_00930 3.8e-85 S membrane transporter protein
MGECLEDA_00931 7.1e-98 K Bacterial regulatory proteins, tetR family
MGECLEDA_00932 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MGECLEDA_00933 2.9e-78 3.6.1.55 F NUDIX domain
MGECLEDA_00934 1.3e-48 sugE U Multidrug resistance protein
MGECLEDA_00935 1.2e-26
MGECLEDA_00936 5.5e-129 pgm3 G Phosphoglycerate mutase family
MGECLEDA_00937 4.7e-125 pgm3 G Phosphoglycerate mutase family
MGECLEDA_00938 0.0 yjbQ P TrkA C-terminal domain protein
MGECLEDA_00939 4.5e-177 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
MGECLEDA_00940 4.2e-110 dedA S SNARE associated Golgi protein
MGECLEDA_00941 0.0 helD 3.6.4.12 L DNA helicase
MGECLEDA_00942 4.6e-166 fabK 1.3.1.9 S Nitronate monooxygenase
MGECLEDA_00943 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
MGECLEDA_00944 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MGECLEDA_00945 6.2e-50
MGECLEDA_00946 3.2e-62 K Helix-turn-helix XRE-family like proteins
MGECLEDA_00948 0.0 L AAA domain
MGECLEDA_00949 9.4e-116 XK27_07075 V CAAX protease self-immunity
MGECLEDA_00950 1.9e-56 hxlR K HxlR-like helix-turn-helix
MGECLEDA_00951 2.5e-234 EGP Major facilitator Superfamily
MGECLEDA_00952 3e-156 S Cysteine-rich secretory protein family
MGECLEDA_00953 2.9e-48 K Cro/C1-type HTH DNA-binding domain
MGECLEDA_00954 3e-69 D nuclear chromosome segregation
MGECLEDA_00955 3.4e-66
MGECLEDA_00956 1.1e-152 S Domain of unknown function (DUF4767)
MGECLEDA_00957 1.9e-48
MGECLEDA_00958 7.4e-38 S MORN repeat
MGECLEDA_00959 0.0 XK27_09800 I Acyltransferase family
MGECLEDA_00960 7.1e-37 S Transglycosylase associated protein
MGECLEDA_00961 2.6e-84
MGECLEDA_00962 7.2e-23
MGECLEDA_00963 8.7e-72 asp S Asp23 family, cell envelope-related function
MGECLEDA_00964 5.3e-72 asp2 S Asp23 family, cell envelope-related function
MGECLEDA_00965 2.6e-146 Q Fumarylacetoacetate (FAA) hydrolase family
MGECLEDA_00966 2.7e-156 yjdB S Domain of unknown function (DUF4767)
MGECLEDA_00967 7.6e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MGECLEDA_00968 1.1e-101 G Glycogen debranching enzyme
MGECLEDA_00969 0.0 pepN 3.4.11.2 E aminopeptidase
MGECLEDA_00970 0.0 N Uncharacterized conserved protein (DUF2075)
MGECLEDA_00971 2.6e-44 S MazG-like family
MGECLEDA_00972 2e-89 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
MGECLEDA_00973 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
MGECLEDA_00975 1.2e-85 S AAA domain
MGECLEDA_00976 2.9e-139 K sequence-specific DNA binding
MGECLEDA_00977 7.8e-97 K Helix-turn-helix domain
MGECLEDA_00978 9.5e-172 K Transcriptional regulator
MGECLEDA_00979 0.0 1.3.5.4 C FMN_bind
MGECLEDA_00981 2.3e-81 rmaD K Transcriptional regulator
MGECLEDA_00982 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MGECLEDA_00983 2.8e-254 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MGECLEDA_00984 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
MGECLEDA_00985 6.7e-278 pipD E Dipeptidase
MGECLEDA_00986 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MGECLEDA_00987 1e-41
MGECLEDA_00988 4.1e-32 L leucine-zipper of insertion element IS481
MGECLEDA_00989 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MGECLEDA_00990 1e-162 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MGECLEDA_00991 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
MGECLEDA_00992 4.3e-138 S NADPH-dependent FMN reductase
MGECLEDA_00993 6.6e-179
MGECLEDA_00994 2.1e-219 yibE S overlaps another CDS with the same product name
MGECLEDA_00995 3.4e-127 yibF S overlaps another CDS with the same product name
MGECLEDA_00996 7.5e-103 3.2.2.20 K FR47-like protein
MGECLEDA_00997 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MGECLEDA_00998 2.1e-48
MGECLEDA_00999 3.4e-191 nlhH_1 I alpha/beta hydrolase fold
MGECLEDA_01000 1e-254 xylP2 G symporter
MGECLEDA_01001 5.2e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MGECLEDA_01002 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MGECLEDA_01003 0.0 asnB 6.3.5.4 E Asparagine synthase
MGECLEDA_01004 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
MGECLEDA_01005 2.2e-120 azlC E branched-chain amino acid
MGECLEDA_01006 4.4e-35 yyaN K MerR HTH family regulatory protein
MGECLEDA_01007 5e-106
MGECLEDA_01008 1.4e-117 S Domain of unknown function (DUF4811)
MGECLEDA_01009 7e-270 lmrB EGP Major facilitator Superfamily
MGECLEDA_01010 1.7e-84 merR K MerR HTH family regulatory protein
MGECLEDA_01011 2.6e-58
MGECLEDA_01012 2e-120 sirR K iron dependent repressor
MGECLEDA_01013 6e-31 cspC K Cold shock protein
MGECLEDA_01014 1.5e-130 thrE S Putative threonine/serine exporter
MGECLEDA_01015 2.2e-76 S Threonine/Serine exporter, ThrE
MGECLEDA_01016 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MGECLEDA_01017 2.3e-119 lssY 3.6.1.27 I phosphatase
MGECLEDA_01018 2e-154 I alpha/beta hydrolase fold
MGECLEDA_01019 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
MGECLEDA_01020 4.2e-92 K Transcriptional regulator
MGECLEDA_01021 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MGECLEDA_01022 1.5e-264 lysP E amino acid
MGECLEDA_01023 2.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MGECLEDA_01024 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MGECLEDA_01025 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MGECLEDA_01033 6.9e-78 ctsR K Belongs to the CtsR family
MGECLEDA_01034 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MGECLEDA_01035 1.5e-109 K Bacterial regulatory proteins, tetR family
MGECLEDA_01036 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MGECLEDA_01037 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MGECLEDA_01038 6.6e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MGECLEDA_01039 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MGECLEDA_01040 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MGECLEDA_01041 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MGECLEDA_01042 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MGECLEDA_01043 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MGECLEDA_01044 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
MGECLEDA_01045 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MGECLEDA_01046 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MGECLEDA_01047 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MGECLEDA_01048 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MGECLEDA_01049 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MGECLEDA_01050 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MGECLEDA_01051 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
MGECLEDA_01052 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MGECLEDA_01053 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MGECLEDA_01054 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MGECLEDA_01055 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MGECLEDA_01056 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MGECLEDA_01057 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MGECLEDA_01058 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MGECLEDA_01059 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MGECLEDA_01060 2.2e-24 rpmD J Ribosomal protein L30
MGECLEDA_01061 6.3e-70 rplO J Binds to the 23S rRNA
MGECLEDA_01062 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MGECLEDA_01063 6.2e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MGECLEDA_01064 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MGECLEDA_01065 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MGECLEDA_01066 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MGECLEDA_01067 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MGECLEDA_01068 2.1e-61 rplQ J Ribosomal protein L17
MGECLEDA_01069 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MGECLEDA_01070 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
MGECLEDA_01071 1.4e-86 ynhH S NusG domain II
MGECLEDA_01072 0.0 ndh 1.6.99.3 C NADH dehydrogenase
MGECLEDA_01073 3.5e-142 cad S FMN_bind
MGECLEDA_01074 1.5e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MGECLEDA_01075 4.7e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MGECLEDA_01076 2.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MGECLEDA_01077 3.2e-144 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MGECLEDA_01078 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MGECLEDA_01079 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MGECLEDA_01080 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MGECLEDA_01081 8.9e-164 degV S Uncharacterised protein, DegV family COG1307
MGECLEDA_01082 6.3e-183 ywhK S Membrane
MGECLEDA_01083 3.9e-54 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MGECLEDA_01084 9.6e-132 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MGECLEDA_01085 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MGECLEDA_01086 1.2e-163 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MGECLEDA_01087 3.1e-50 aroF 2.5.1.54 E DAHP synthetase I family
MGECLEDA_01088 5.4e-124 aroF 2.5.1.54 E DAHP synthetase I family
MGECLEDA_01089 4.9e-196 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MGECLEDA_01091 1.4e-262 P Sodium:sulfate symporter transmembrane region
MGECLEDA_01092 9.1e-53 yitW S Iron-sulfur cluster assembly protein
MGECLEDA_01093 5.4e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
MGECLEDA_01094 4.4e-177 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
MGECLEDA_01095 7.7e-199 K Helix-turn-helix domain
MGECLEDA_01096 2.4e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MGECLEDA_01097 4.5e-132 mntB 3.6.3.35 P ABC transporter
MGECLEDA_01098 4.8e-141 mtsB U ABC 3 transport family
MGECLEDA_01099 1.2e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
MGECLEDA_01100 3.1e-50
MGECLEDA_01101 6e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MGECLEDA_01102 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
MGECLEDA_01103 2.9e-179 citR K sugar-binding domain protein
MGECLEDA_01104 1.7e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
MGECLEDA_01105 9.7e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MGECLEDA_01106 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
MGECLEDA_01107 5.5e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
MGECLEDA_01108 4.6e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
MGECLEDA_01109 1.3e-143 L PFAM Integrase, catalytic core
MGECLEDA_01110 1.8e-170 L Transposase and inactivated derivatives, IS30 family
MGECLEDA_01112 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MGECLEDA_01113 3.9e-262 frdC 1.3.5.4 C FAD binding domain
MGECLEDA_01114 3.6e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MGECLEDA_01115 4.9e-162 mleR K LysR family transcriptional regulator
MGECLEDA_01116 4e-167 mleR K LysR family
MGECLEDA_01117 1.8e-306 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MGECLEDA_01118 1.4e-165 mleP S Sodium Bile acid symporter family
MGECLEDA_01119 5.8e-253 yfnA E Amino Acid
MGECLEDA_01120 3e-99 S ECF transporter, substrate-specific component
MGECLEDA_01121 1.8e-23
MGECLEDA_01122 9.8e-302 S Alpha beta
MGECLEDA_01123 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
MGECLEDA_01124 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MGECLEDA_01125 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MGECLEDA_01126 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MGECLEDA_01127 5.9e-156 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
MGECLEDA_01128 2.8e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MGECLEDA_01129 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MGECLEDA_01130 3.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
MGECLEDA_01131 3.1e-113 acmA 3.2.1.17 NU mannosyl-glycoprotein
MGECLEDA_01132 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MGECLEDA_01133 1.5e-92 S UPF0316 protein
MGECLEDA_01134 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MGECLEDA_01135 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MGECLEDA_01136 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MGECLEDA_01137 2.6e-198 camS S sex pheromone
MGECLEDA_01138 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MGECLEDA_01139 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MGECLEDA_01140 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MGECLEDA_01141 1e-190 yegS 2.7.1.107 G Lipid kinase
MGECLEDA_01142 1.4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MGECLEDA_01143 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
MGECLEDA_01144 0.0 yfgQ P E1-E2 ATPase
MGECLEDA_01145 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_01146 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
MGECLEDA_01147 2.3e-151 gntR K rpiR family
MGECLEDA_01148 1.2e-143 lys M Glycosyl hydrolases family 25
MGECLEDA_01149 1.1e-62 S Domain of unknown function (DUF4828)
MGECLEDA_01150 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
MGECLEDA_01151 8.4e-190 mocA S Oxidoreductase
MGECLEDA_01152 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
MGECLEDA_01154 2.3e-75 T Universal stress protein family
MGECLEDA_01155 1e-243 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_01156 1.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
MGECLEDA_01158 1.3e-73
MGECLEDA_01159 5e-107
MGECLEDA_01160 9.9e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MGECLEDA_01161 6.9e-220 pbpX1 V Beta-lactamase
MGECLEDA_01162 6.8e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MGECLEDA_01163 1.4e-154 yihY S Belongs to the UPF0761 family
MGECLEDA_01164 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MGECLEDA_01165 1.5e-56 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MGECLEDA_01168 3.6e-62 xerC L Belongs to the 'phage' integrase family
MGECLEDA_01171 4.3e-27 6.3.2.2, 6.3.2.4 M Belongs to the D-alanine--D-alanine ligase family
MGECLEDA_01172 2.8e-21 M domain protein
MGECLEDA_01173 1.5e-26 M self proteolysis
MGECLEDA_01174 8.2e-22 S Barstar (barnase inhibitor)
MGECLEDA_01176 4.1e-167
MGECLEDA_01178 8.1e-80
MGECLEDA_01179 2.5e-15
MGECLEDA_01180 1.2e-46
MGECLEDA_01181 8.2e-14
MGECLEDA_01182 1.1e-23 S Barstar (barnase inhibitor)
MGECLEDA_01183 8.1e-55 S SMI1-KNR4 cell-wall
MGECLEDA_01184 6.2e-37 S Uncharacterized protein conserved in bacteria (DUF2247)
MGECLEDA_01185 2.2e-133 cps3A S Glycosyltransferase like family 2
MGECLEDA_01186 2.8e-179 cps3B S Glycosyltransferase like family 2
MGECLEDA_01187 6.1e-221 glf 5.4.99.9 M UDP-galactopyranose mutase
MGECLEDA_01188 7.9e-202 cps3D
MGECLEDA_01189 4.8e-111 cps3E
MGECLEDA_01190 5.6e-164 cps3F
MGECLEDA_01191 3.6e-202 cps3H
MGECLEDA_01192 3.9e-201 cps3I G Acyltransferase family
MGECLEDA_01193 8.8e-147 cps1D M Domain of unknown function (DUF4422)
MGECLEDA_01194 1e-241 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
MGECLEDA_01195 3.2e-121 rfbP M Bacterial sugar transferase
MGECLEDA_01196 3.2e-52
MGECLEDA_01197 7.3e-33 S Protein of unknown function (DUF2922)
MGECLEDA_01198 7e-30
MGECLEDA_01199 6.2e-25
MGECLEDA_01200 1.5e-100 K DNA-templated transcription, initiation
MGECLEDA_01201 3.9e-125
MGECLEDA_01202 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
MGECLEDA_01203 4.1e-106 ygaC J Belongs to the UPF0374 family
MGECLEDA_01204 7.9e-135 cwlO M NlpC/P60 family
MGECLEDA_01205 7.8e-48 K sequence-specific DNA binding
MGECLEDA_01206 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
MGECLEDA_01207 9.8e-152 pbpX V Beta-lactamase
MGECLEDA_01208 4.1e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MGECLEDA_01209 6e-187 yueF S AI-2E family transporter
MGECLEDA_01210 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MGECLEDA_01211 9.5e-213 gntP EG Gluconate
MGECLEDA_01212 4.6e-293 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MGECLEDA_01213 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
MGECLEDA_01214 9.8e-255 gor 1.8.1.7 C Glutathione reductase
MGECLEDA_01215 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MGECLEDA_01216 5.9e-274
MGECLEDA_01217 4.2e-197 M MucBP domain
MGECLEDA_01218 7.1e-161 lysR5 K LysR substrate binding domain
MGECLEDA_01219 5.5e-126 yxaA S membrane transporter protein
MGECLEDA_01220 3.2e-57 ywjH S Protein of unknown function (DUF1634)
MGECLEDA_01221 2.3e-311 oppA E ABC transporter, substratebinding protein
MGECLEDA_01222 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MGECLEDA_01223 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MGECLEDA_01224 9.2e-203 oppD P Belongs to the ABC transporter superfamily
MGECLEDA_01225 1.8e-181 oppF P Belongs to the ABC transporter superfamily
MGECLEDA_01226 1e-63 K Winged helix DNA-binding domain
MGECLEDA_01227 1.6e-102 L Integrase
MGECLEDA_01228 0.0 clpE O Belongs to the ClpA ClpB family
MGECLEDA_01229 6.5e-30
MGECLEDA_01230 2.7e-39 ptsH G phosphocarrier protein HPR
MGECLEDA_01231 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MGECLEDA_01232 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MGECLEDA_01233 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
MGECLEDA_01234 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MGECLEDA_01235 1.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MGECLEDA_01236 1.8e-228 patA 2.6.1.1 E Aminotransferase
MGECLEDA_01237 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
MGECLEDA_01238 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MGECLEDA_01244 5.1e-08
MGECLEDA_01250 1.4e-90 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
MGECLEDA_01251 1.8e-182 P secondary active sulfate transmembrane transporter activity
MGECLEDA_01252 5.8e-94
MGECLEDA_01253 2e-94 K Acetyltransferase (GNAT) domain
MGECLEDA_01254 1.1e-155 T Calcineurin-like phosphoesterase superfamily domain
MGECLEDA_01256 5.2e-232 mntH P H( )-stimulated, divalent metal cation uptake system
MGECLEDA_01257 7.6e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MGECLEDA_01258 1.7e-254 mmuP E amino acid
MGECLEDA_01259 1.7e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MGECLEDA_01260 9.3e-294 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
MGECLEDA_01261 3.1e-122
MGECLEDA_01262 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MGECLEDA_01263 1.4e-278 bmr3 EGP Major facilitator Superfamily
MGECLEDA_01265 1.8e-137 N Cell shape-determining protein MreB
MGECLEDA_01266 0.0 S Pfam Methyltransferase
MGECLEDA_01267 2.6e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
MGECLEDA_01268 9.1e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
MGECLEDA_01269 4.2e-29
MGECLEDA_01270 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
MGECLEDA_01271 3e-124 3.6.1.27 I Acid phosphatase homologues
MGECLEDA_01272 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MGECLEDA_01273 3e-301 ytgP S Polysaccharide biosynthesis protein
MGECLEDA_01274 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MGECLEDA_01275 6.4e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MGECLEDA_01276 2.2e-273 pepV 3.5.1.18 E dipeptidase PepV
MGECLEDA_01277 4.1e-84 uspA T Belongs to the universal stress protein A family
MGECLEDA_01278 1.8e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
MGECLEDA_01279 9.9e-172 ugpA U Binding-protein-dependent transport system inner membrane component
MGECLEDA_01280 1.1e-150 ugpE G ABC transporter permease
MGECLEDA_01281 4.2e-261 ugpB G Bacterial extracellular solute-binding protein
MGECLEDA_01282 1.3e-125 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MGECLEDA_01283 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
MGECLEDA_01284 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MGECLEDA_01285 4.6e-180 XK27_06930 V domain protein
MGECLEDA_01287 2.5e-127 V Transport permease protein
MGECLEDA_01288 7.4e-155 V ABC transporter
MGECLEDA_01289 3.7e-174 K LytTr DNA-binding domain
MGECLEDA_01291 1.2e-154 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MGECLEDA_01292 1.6e-64 K helix_turn_helix, mercury resistance
MGECLEDA_01293 3.5e-117 GM NAD(P)H-binding
MGECLEDA_01294 3.8e-160 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MGECLEDA_01295 3.2e-147 S Sucrose-6F-phosphate phosphohydrolase
MGECLEDA_01296 1.7e-108
MGECLEDA_01297 2.2e-224 pltK 2.7.13.3 T GHKL domain
MGECLEDA_01298 1.6e-137 pltR K LytTr DNA-binding domain
MGECLEDA_01299 4.5e-55
MGECLEDA_01300 2.5e-59
MGECLEDA_01301 3e-114 S CAAX protease self-immunity
MGECLEDA_01302 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
MGECLEDA_01303 1e-90
MGECLEDA_01304 2.5e-46
MGECLEDA_01305 0.0 uvrA2 L ABC transporter
MGECLEDA_01307 3.3e-211 S Phage integrase family
MGECLEDA_01310 2.4e-25 S Short C-terminal domain
MGECLEDA_01311 1.5e-36 S Pfam:Peptidase_M78
MGECLEDA_01312 6.1e-25 ps115 K Helix-turn-helix XRE-family like proteins
MGECLEDA_01314 2.4e-93 kilA K BRO family, N-terminal domain
MGECLEDA_01317 1.3e-51 S Domain of unknown function (DUF771)
MGECLEDA_01322 9.3e-08
MGECLEDA_01325 5.7e-72 L DnaD domain protein
MGECLEDA_01326 1.7e-162 dnaC L IstB-like ATP binding protein
MGECLEDA_01328 6e-46
MGECLEDA_01330 6.4e-106 2.1.1.37 L C-5 cytosine-specific DNA methylase
MGECLEDA_01331 6e-34
MGECLEDA_01332 1.1e-63 S Transcriptional regulator, RinA family
MGECLEDA_01333 4.2e-43
MGECLEDA_01334 4.1e-13 V HNH nucleases
MGECLEDA_01336 1.6e-72 L HNH nucleases
MGECLEDA_01337 9.3e-26 S HNH endonuclease
MGECLEDA_01338 8.2e-76 S Phage terminase, small subunit
MGECLEDA_01339 0.0 S Phage Terminase
MGECLEDA_01340 2.8e-25 S Protein of unknown function (DUF1056)
MGECLEDA_01341 3.1e-223 S Phage portal protein
MGECLEDA_01342 1.6e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MGECLEDA_01343 3.2e-215 S peptidase activity
MGECLEDA_01344 3.3e-50 S Phage gp6-like head-tail connector protein
MGECLEDA_01345 1.7e-57 S Phage head-tail joining protein
MGECLEDA_01346 7.1e-63 S Bacteriophage HK97-gp10, putative tail-component
MGECLEDA_01347 1.4e-57 S Protein of unknown function (DUF806)
MGECLEDA_01348 2.9e-106 S Phage tail tube protein
MGECLEDA_01349 1.6e-56 S Phage tail assembly chaperone proteins, TAC
MGECLEDA_01350 1.5e-23
MGECLEDA_01351 0.0 D NLP P60 protein
MGECLEDA_01352 1.7e-214 S Phage tail protein
MGECLEDA_01353 8.2e-292 S Phage minor structural protein
MGECLEDA_01354 1.3e-188
MGECLEDA_01357 1.8e-93
MGECLEDA_01358 8.6e-23
MGECLEDA_01359 3.8e-202 lys M Glycosyl hydrolases family 25
MGECLEDA_01360 1.3e-36 S Haemolysin XhlA
MGECLEDA_01361 1.1e-30 hol S Bacteriophage holin
MGECLEDA_01363 5.9e-52
MGECLEDA_01364 3.5e-10
MGECLEDA_01365 2.1e-180
MGECLEDA_01366 1.9e-89 gtcA S Teichoic acid glycosylation protein
MGECLEDA_01367 3.6e-58 S Protein of unknown function (DUF1516)
MGECLEDA_01368 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MGECLEDA_01369 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MGECLEDA_01370 1.6e-307 S Protein conserved in bacteria
MGECLEDA_01371 9.7e-230 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
MGECLEDA_01372 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
MGECLEDA_01373 1.4e-173 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
MGECLEDA_01374 1.1e-303 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
MGECLEDA_01375 0.0 yfbS P Sodium:sulfate symporter transmembrane region
MGECLEDA_01376 2.1e-244 dinF V MatE
MGECLEDA_01377 1.9e-31
MGECLEDA_01380 1.7e-78 elaA S Acetyltransferase (GNAT) domain
MGECLEDA_01381 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MGECLEDA_01382 6.7e-81
MGECLEDA_01383 0.0 yhcA V MacB-like periplasmic core domain
MGECLEDA_01384 7.6e-107
MGECLEDA_01385 0.0 K PRD domain
MGECLEDA_01386 3.1e-62 S Domain of unknown function (DUF3284)
MGECLEDA_01387 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MGECLEDA_01388 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MGECLEDA_01389 6.1e-220 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_01390 6.1e-290 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MGECLEDA_01391 4.4e-147 EGP Major facilitator Superfamily
MGECLEDA_01392 3.1e-56 EGP Major facilitator Superfamily
MGECLEDA_01393 2.7e-114 M ErfK YbiS YcfS YnhG
MGECLEDA_01394 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MGECLEDA_01395 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
MGECLEDA_01396 4e-102 argO S LysE type translocator
MGECLEDA_01397 7.1e-214 arcT 2.6.1.1 E Aminotransferase
MGECLEDA_01398 1.3e-76 argR K Regulates arginine biosynthesis genes
MGECLEDA_01399 2.9e-12
MGECLEDA_01400 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MGECLEDA_01401 1e-54 yheA S Belongs to the UPF0342 family
MGECLEDA_01402 1.8e-231 yhaO L Ser Thr phosphatase family protein
MGECLEDA_01403 0.0 L AAA domain
MGECLEDA_01404 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
MGECLEDA_01405 2.1e-216
MGECLEDA_01406 7.6e-91 3.4.21.102 M Peptidase family S41
MGECLEDA_01407 1.1e-56 3.4.21.102 M Peptidase family S41
MGECLEDA_01408 1.2e-177 K LysR substrate binding domain
MGECLEDA_01409 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
MGECLEDA_01410 0.0 1.3.5.4 C FAD binding domain
MGECLEDA_01411 3.8e-99
MGECLEDA_01412 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MGECLEDA_01413 7.6e-61 M domain protein
MGECLEDA_01414 8e-137 M domain protein
MGECLEDA_01415 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
MGECLEDA_01416 1e-200 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MGECLEDA_01417 4.6e-272 mutS L ATPase domain of DNA mismatch repair MUTS family
MGECLEDA_01418 1e-268 mutS L MutS domain V
MGECLEDA_01419 6.1e-185 ykoT GT2 M Glycosyl transferase family 2
MGECLEDA_01420 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MGECLEDA_01421 4.8e-67 S NUDIX domain
MGECLEDA_01422 0.0 S membrane
MGECLEDA_01423 3.2e-171 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MGECLEDA_01424 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MGECLEDA_01425 2.6e-222 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MGECLEDA_01426 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MGECLEDA_01427 9.3e-106 GBS0088 S Nucleotidyltransferase
MGECLEDA_01428 1.4e-106
MGECLEDA_01429 5.1e-116 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MGECLEDA_01430 3.3e-112 K Bacterial regulatory proteins, tetR family
MGECLEDA_01431 2.1e-241 npr 1.11.1.1 C NADH oxidase
MGECLEDA_01432 0.0
MGECLEDA_01433 7.9e-61
MGECLEDA_01434 1.4e-192 S Fn3-like domain
MGECLEDA_01435 4e-103 S WxL domain surface cell wall-binding
MGECLEDA_01436 7.9e-78 S WxL domain surface cell wall-binding
MGECLEDA_01437 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MGECLEDA_01438 2e-42
MGECLEDA_01439 9.9e-82 hit FG histidine triad
MGECLEDA_01440 1.6e-134 ecsA V ABC transporter, ATP-binding protein
MGECLEDA_01441 3.1e-223 ecsB U ABC transporter
MGECLEDA_01442 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
MGECLEDA_01443 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MGECLEDA_01444 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
MGECLEDA_01445 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MGECLEDA_01446 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MGECLEDA_01447 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MGECLEDA_01448 7.9e-21 S Virus attachment protein p12 family
MGECLEDA_01449 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MGECLEDA_01450 1.3e-34 feoA P FeoA domain
MGECLEDA_01451 4.2e-144 sufC O FeS assembly ATPase SufC
MGECLEDA_01452 2.6e-244 sufD O FeS assembly protein SufD
MGECLEDA_01453 4.4e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MGECLEDA_01454 1.6e-82 nifU C SUF system FeS assembly protein, NifU family
MGECLEDA_01455 1.2e-271 sufB O assembly protein SufB
MGECLEDA_01456 5.5e-45 yitW S Iron-sulfur cluster assembly protein
MGECLEDA_01457 2.3e-111 hipB K Helix-turn-helix
MGECLEDA_01458 4.5e-121 ybhL S Belongs to the BI1 family
MGECLEDA_01459 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MGECLEDA_01460 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MGECLEDA_01461 2.7e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MGECLEDA_01462 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MGECLEDA_01463 1.5e-250 dnaB L replication initiation and membrane attachment
MGECLEDA_01464 3.3e-172 dnaI L Primosomal protein DnaI
MGECLEDA_01465 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MGECLEDA_01466 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MGECLEDA_01467 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MGECLEDA_01468 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MGECLEDA_01469 9.9e-57
MGECLEDA_01470 5e-240 yrvN L AAA C-terminal domain
MGECLEDA_01471 2.5e-197 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MGECLEDA_01472 1e-62 hxlR K Transcriptional regulator, HxlR family
MGECLEDA_01473 2.6e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
MGECLEDA_01474 2.7e-249 pgaC GT2 M Glycosyl transferase
MGECLEDA_01475 1.3e-79
MGECLEDA_01476 1.4e-98 yqeG S HAD phosphatase, family IIIA
MGECLEDA_01477 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
MGECLEDA_01478 1.1e-50 yhbY J RNA-binding protein
MGECLEDA_01479 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MGECLEDA_01480 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MGECLEDA_01481 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MGECLEDA_01482 4.4e-140 yqeM Q Methyltransferase
MGECLEDA_01483 1.9e-217 ylbM S Belongs to the UPF0348 family
MGECLEDA_01484 1.6e-97 yceD S Uncharacterized ACR, COG1399
MGECLEDA_01485 2.2e-89 S Peptidase propeptide and YPEB domain
MGECLEDA_01486 2.5e-167 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MGECLEDA_01487 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MGECLEDA_01488 1.2e-244 rarA L recombination factor protein RarA
MGECLEDA_01489 4.3e-121 K response regulator
MGECLEDA_01490 8e-307 arlS 2.7.13.3 T Histidine kinase
MGECLEDA_01491 7.6e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MGECLEDA_01492 0.0 sbcC L Putative exonuclease SbcCD, C subunit
MGECLEDA_01493 5e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MGECLEDA_01494 1.1e-93 S SdpI/YhfL protein family
MGECLEDA_01495 1.4e-143 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MGECLEDA_01496 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MGECLEDA_01497 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MGECLEDA_01498 6.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MGECLEDA_01499 7.4e-64 yodB K Transcriptional regulator, HxlR family
MGECLEDA_01500 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MGECLEDA_01501 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MGECLEDA_01502 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MGECLEDA_01503 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
MGECLEDA_01504 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MGECLEDA_01505 2.8e-94 liaI S membrane
MGECLEDA_01506 2e-74 XK27_02470 K LytTr DNA-binding domain
MGECLEDA_01507 1.5e-54 yneR S Belongs to the HesB IscA family
MGECLEDA_01508 0.0 S membrane
MGECLEDA_01509 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MGECLEDA_01510 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MGECLEDA_01511 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MGECLEDA_01512 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
MGECLEDA_01513 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
MGECLEDA_01514 5.7e-180 glk 2.7.1.2 G Glucokinase
MGECLEDA_01515 1e-108 pepE 3.4.13.21 E Belongs to the peptidase S51 family
MGECLEDA_01516 4.4e-68 yqhL P Rhodanese-like protein
MGECLEDA_01517 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
MGECLEDA_01518 1.7e-139 glpQ 3.1.4.46 C phosphodiesterase
MGECLEDA_01519 2.7e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MGECLEDA_01520 4.6e-64 glnR K Transcriptional regulator
MGECLEDA_01521 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
MGECLEDA_01522 2.5e-161
MGECLEDA_01523 8.8e-181
MGECLEDA_01524 3.1e-98 dut S Protein conserved in bacteria
MGECLEDA_01525 5.3e-56
MGECLEDA_01526 1.7e-30
MGECLEDA_01529 5.4e-19
MGECLEDA_01530 1.8e-89 K Transcriptional regulator
MGECLEDA_01531 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MGECLEDA_01532 7.2e-53 ysxB J Cysteine protease Prp
MGECLEDA_01533 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MGECLEDA_01534 1.6e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MGECLEDA_01535 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MGECLEDA_01536 3.5e-74 yqhY S Asp23 family, cell envelope-related function
MGECLEDA_01537 5.8e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MGECLEDA_01538 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MGECLEDA_01539 9.3e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MGECLEDA_01540 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MGECLEDA_01541 6.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MGECLEDA_01542 9e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MGECLEDA_01543 7.4e-77 argR K Regulates arginine biosynthesis genes
MGECLEDA_01544 6.3e-307 recN L May be involved in recombinational repair of damaged DNA
MGECLEDA_01545 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
MGECLEDA_01546 1.2e-104 opuCB E ABC transporter permease
MGECLEDA_01547 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MGECLEDA_01548 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
MGECLEDA_01549 1.7e-54
MGECLEDA_01550 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MGECLEDA_01551 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MGECLEDA_01552 4e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MGECLEDA_01553 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MGECLEDA_01554 4.2e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MGECLEDA_01555 1.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MGECLEDA_01556 1.7e-134 stp 3.1.3.16 T phosphatase
MGECLEDA_01557 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MGECLEDA_01558 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MGECLEDA_01559 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MGECLEDA_01560 5.8e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
MGECLEDA_01561 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MGECLEDA_01562 1.8e-57 asp S Asp23 family, cell envelope-related function
MGECLEDA_01563 0.0 yloV S DAK2 domain fusion protein YloV
MGECLEDA_01564 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MGECLEDA_01565 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MGECLEDA_01566 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MGECLEDA_01567 1.3e-128 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MGECLEDA_01568 0.0 smc D Required for chromosome condensation and partitioning
MGECLEDA_01569 6.6e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MGECLEDA_01570 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MGECLEDA_01571 2.9e-220 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MGECLEDA_01572 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MGECLEDA_01573 2.6e-39 ylqC S Belongs to the UPF0109 family
MGECLEDA_01574 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MGECLEDA_01575 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MGECLEDA_01576 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MGECLEDA_01577 1.4e-50
MGECLEDA_01578 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
MGECLEDA_01579 1.4e-86
MGECLEDA_01580 8.7e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
MGECLEDA_01581 4.2e-268 XK27_00765
MGECLEDA_01583 1.9e-267 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
MGECLEDA_01584 4.2e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
MGECLEDA_01585 1.2e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MGECLEDA_01586 2.4e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MGECLEDA_01587 2.2e-108 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MGECLEDA_01588 6.6e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MGECLEDA_01589 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MGECLEDA_01590 3.5e-08 entB 3.5.1.19 Q Isochorismatase family
MGECLEDA_01591 4.1e-71 entB 3.5.1.19 Q Isochorismatase family
MGECLEDA_01592 6.5e-176 1.6.5.5 C Zinc-binding dehydrogenase
MGECLEDA_01593 4.5e-67 ybbJ K Acetyltransferase (GNAT) family
MGECLEDA_01594 1.7e-216 E glutamate:sodium symporter activity
MGECLEDA_01595 1.1e-214 3.5.1.47 E Peptidase family M20/M25/M40
MGECLEDA_01596 2.7e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MGECLEDA_01597 8.5e-60 S Protein of unknown function (DUF1648)
MGECLEDA_01598 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MGECLEDA_01599 3.8e-179 yneE K Transcriptional regulator
MGECLEDA_01600 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MGECLEDA_01601 1.7e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MGECLEDA_01602 1.3e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MGECLEDA_01603 2.9e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MGECLEDA_01604 1.2e-126 IQ reductase
MGECLEDA_01605 1.6e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MGECLEDA_01606 1.7e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MGECLEDA_01607 1e-69 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MGECLEDA_01608 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MGECLEDA_01609 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MGECLEDA_01610 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MGECLEDA_01611 9.9e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MGECLEDA_01612 4.9e-99 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MGECLEDA_01613 2.2e-123 S Protein of unknown function (DUF554)
MGECLEDA_01614 9.4e-161 K LysR substrate binding domain
MGECLEDA_01615 4.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
MGECLEDA_01616 3.8e-193 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MGECLEDA_01617 2.3e-93 K transcriptional regulator
MGECLEDA_01618 8.6e-304 norB EGP Major Facilitator
MGECLEDA_01619 1.2e-139 f42a O Band 7 protein
MGECLEDA_01620 1.9e-26 L Pfam:Integrase_AP2
MGECLEDA_01621 1.2e-25 L Phage integrase, N-terminal SAM-like domain
MGECLEDA_01623 4e-09
MGECLEDA_01625 8.5e-54
MGECLEDA_01626 7.7e-22
MGECLEDA_01627 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MGECLEDA_01628 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
MGECLEDA_01629 5.8e-48 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
MGECLEDA_01630 7.9e-41
MGECLEDA_01631 1.9e-67 tspO T TspO/MBR family
MGECLEDA_01632 6.3e-76 uspA T Belongs to the universal stress protein A family
MGECLEDA_01633 8e-66 S Protein of unknown function (DUF805)
MGECLEDA_01634 4.1e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
MGECLEDA_01635 3.5e-36
MGECLEDA_01636 3.1e-14
MGECLEDA_01637 6.5e-41 S transglycosylase associated protein
MGECLEDA_01638 4.8e-29 S CsbD-like
MGECLEDA_01639 9.4e-40
MGECLEDA_01640 8.6e-281 pipD E Dipeptidase
MGECLEDA_01641 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MGECLEDA_01642 1.3e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MGECLEDA_01643 6.1e-171 2.5.1.74 H UbiA prenyltransferase family
MGECLEDA_01644 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
MGECLEDA_01645 7.3e-49
MGECLEDA_01646 2.4e-43
MGECLEDA_01647 9.6e-258 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MGECLEDA_01648 1.4e-265 yfnA E Amino Acid
MGECLEDA_01649 1.2e-149 yitU 3.1.3.104 S hydrolase
MGECLEDA_01650 9.4e-269 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MGECLEDA_01651 1.5e-89 S Domain of unknown function (DUF4767)
MGECLEDA_01652 2.5e-250 malT G Major Facilitator
MGECLEDA_01653 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MGECLEDA_01654 1.5e-194 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MGECLEDA_01655 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MGECLEDA_01656 7.6e-205 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MGECLEDA_01657 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MGECLEDA_01658 1.2e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MGECLEDA_01659 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MGECLEDA_01660 2.1e-72 ypmB S protein conserved in bacteria
MGECLEDA_01661 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MGECLEDA_01662 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MGECLEDA_01663 1.3e-128 dnaD L Replication initiation and membrane attachment
MGECLEDA_01665 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MGECLEDA_01666 7.7e-99 metI P ABC transporter permease
MGECLEDA_01667 2.7e-157 metQ_4 P Belongs to the nlpA lipoprotein family
MGECLEDA_01668 7.6e-83 uspA T Universal stress protein family
MGECLEDA_01669 1.9e-303 ftpA P Binding-protein-dependent transport system inner membrane component
MGECLEDA_01670 4.5e-183 ftpB P Bacterial extracellular solute-binding protein
MGECLEDA_01671 2.8e-179 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
MGECLEDA_01672 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MGECLEDA_01673 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MGECLEDA_01674 8.3e-110 ypsA S Belongs to the UPF0398 family
MGECLEDA_01675 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MGECLEDA_01677 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MGECLEDA_01678 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
MGECLEDA_01679 6.1e-211 P Major Facilitator Superfamily
MGECLEDA_01680 4e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MGECLEDA_01681 2.6e-73 S SnoaL-like domain
MGECLEDA_01682 7.4e-242 M Glycosyltransferase, group 2 family protein
MGECLEDA_01683 5.6e-208 mccF V LD-carboxypeptidase
MGECLEDA_01684 1.4e-78 K Acetyltransferase (GNAT) domain
MGECLEDA_01685 6.9e-240 M hydrolase, family 25
MGECLEDA_01686 1.6e-182 mccF 3.4.17.13 V LD-carboxypeptidase
MGECLEDA_01687 9.2e-125
MGECLEDA_01688 6.6e-122 3.6.3.35 P ATPases associated with a variety of cellular activities
MGECLEDA_01689 2.1e-194
MGECLEDA_01690 1.5e-146 S hydrolase activity, acting on ester bonds
MGECLEDA_01691 2.1e-210 yurR 1.4.5.1 E FAD dependent oxidoreductase
MGECLEDA_01692 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
MGECLEDA_01693 3.3e-62 esbA S Family of unknown function (DUF5322)
MGECLEDA_01694 1.7e-293 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MGECLEDA_01695 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MGECLEDA_01696 1e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MGECLEDA_01697 1.3e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MGECLEDA_01698 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
MGECLEDA_01699 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MGECLEDA_01700 4e-288 S Bacterial membrane protein, YfhO
MGECLEDA_01701 6.4e-113 pgm5 G Phosphoglycerate mutase family
MGECLEDA_01702 5.8e-70 frataxin S Domain of unknown function (DU1801)
MGECLEDA_01705 5.5e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
MGECLEDA_01706 1.3e-68 S LuxR family transcriptional regulator
MGECLEDA_01707 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
MGECLEDA_01708 9.7e-91 3.6.1.55 F NUDIX domain
MGECLEDA_01709 8.6e-162 V ABC transporter, ATP-binding protein
MGECLEDA_01710 3.5e-132 S ABC-2 family transporter protein
MGECLEDA_01711 0.0 FbpA K Fibronectin-binding protein
MGECLEDA_01712 1.9e-66 K Transcriptional regulator
MGECLEDA_01713 7e-161 degV S EDD domain protein, DegV family
MGECLEDA_01714 1.9e-77 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
MGECLEDA_01715 3.4e-132 S Protein of unknown function (DUF975)
MGECLEDA_01716 1.6e-09
MGECLEDA_01717 1.6e-48
MGECLEDA_01718 1.4e-147 2.7.7.12 C Domain of unknown function (DUF4931)
MGECLEDA_01719 1.6e-211 pmrB EGP Major facilitator Superfamily
MGECLEDA_01720 4.6e-12
MGECLEDA_01721 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
MGECLEDA_01722 5.2e-129 yejC S Protein of unknown function (DUF1003)
MGECLEDA_01723 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
MGECLEDA_01724 5.4e-245 cycA E Amino acid permease
MGECLEDA_01725 8.6e-122
MGECLEDA_01726 4.1e-59
MGECLEDA_01727 1.8e-279 lldP C L-lactate permease
MGECLEDA_01728 1.3e-225
MGECLEDA_01729 3.7e-128 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MGECLEDA_01730 3.3e-195 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MGECLEDA_01731 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MGECLEDA_01732 8.5e-93 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MGECLEDA_01733 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
MGECLEDA_01734 4.1e-240 gshR1 1.8.1.7 C Glutathione reductase
MGECLEDA_01735 9e-50
MGECLEDA_01736 9.3e-242 M Glycosyl transferase family group 2
MGECLEDA_01737 9.8e-275 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MGECLEDA_01738 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain
MGECLEDA_01739 4.2e-32 S YozE SAM-like fold
MGECLEDA_01740 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MGECLEDA_01741 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MGECLEDA_01742 1.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
MGECLEDA_01743 3.8e-176 K Transcriptional regulator
MGECLEDA_01744 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MGECLEDA_01745 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MGECLEDA_01746 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MGECLEDA_01747 2.2e-170 lacX 5.1.3.3 G Aldose 1-epimerase
MGECLEDA_01748 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MGECLEDA_01749 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MGECLEDA_01750 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MGECLEDA_01751 2.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MGECLEDA_01752 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MGECLEDA_01753 3.3e-158 dprA LU DNA protecting protein DprA
MGECLEDA_01754 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MGECLEDA_01755 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MGECLEDA_01756 1.4e-228 XK27_05470 E Methionine synthase
MGECLEDA_01757 2.3e-170 cpsY K Transcriptional regulator, LysR family
MGECLEDA_01758 2.3e-173 L restriction endonuclease
MGECLEDA_01759 3.6e-123 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MGECLEDA_01760 7.4e-197 XK27_00915 C Luciferase-like monooxygenase
MGECLEDA_01761 7.3e-251 emrY EGP Major facilitator Superfamily
MGECLEDA_01762 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MGECLEDA_01763 3.4e-35 yozE S Belongs to the UPF0346 family
MGECLEDA_01764 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MGECLEDA_01765 1.4e-149 ypmR E GDSL-like Lipase/Acylhydrolase
MGECLEDA_01766 5.1e-148 DegV S EDD domain protein, DegV family
MGECLEDA_01767 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MGECLEDA_01768 1e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MGECLEDA_01769 0.0 yfmR S ABC transporter, ATP-binding protein
MGECLEDA_01770 9.6e-85
MGECLEDA_01771 7.2e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MGECLEDA_01772 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MGECLEDA_01773 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
MGECLEDA_01774 4.7e-206 S Tetratricopeptide repeat protein
MGECLEDA_01775 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MGECLEDA_01776 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MGECLEDA_01777 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
MGECLEDA_01778 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MGECLEDA_01779 2e-19 M Lysin motif
MGECLEDA_01780 2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
MGECLEDA_01781 9.9e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
MGECLEDA_01782 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MGECLEDA_01783 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MGECLEDA_01784 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MGECLEDA_01785 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MGECLEDA_01786 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MGECLEDA_01787 1.1e-164 xerD D recombinase XerD
MGECLEDA_01788 2.9e-170 cvfB S S1 domain
MGECLEDA_01789 1.5e-74 yeaL S Protein of unknown function (DUF441)
MGECLEDA_01790 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MGECLEDA_01791 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MGECLEDA_01792 0.0 dnaE 2.7.7.7 L DNA polymerase
MGECLEDA_01793 5.6e-29 S Protein of unknown function (DUF2929)
MGECLEDA_01795 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MGECLEDA_01796 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MGECLEDA_01797 8.5e-198 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MGECLEDA_01798 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
MGECLEDA_01799 1.1e-220 M O-Antigen ligase
MGECLEDA_01800 5.4e-120 drrB U ABC-2 type transporter
MGECLEDA_01801 1.8e-165 drrA V ABC transporter
MGECLEDA_01802 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
MGECLEDA_01803 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MGECLEDA_01804 1.9e-62 P Rhodanese Homology Domain
MGECLEDA_01805 2.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
MGECLEDA_01806 5.6e-206
MGECLEDA_01807 5.7e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
MGECLEDA_01808 6.2e-182 C Zinc-binding dehydrogenase
MGECLEDA_01809 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
MGECLEDA_01810 8.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MGECLEDA_01811 8.5e-241 EGP Major facilitator Superfamily
MGECLEDA_01812 2.8e-76 K Transcriptional regulator
MGECLEDA_01813 7e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MGECLEDA_01814 5.8e-176 tanA S alpha beta
MGECLEDA_01815 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MGECLEDA_01816 8e-137 K DeoR C terminal sensor domain
MGECLEDA_01817 1.7e-108 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
MGECLEDA_01818 9.1e-71 yneH 1.20.4.1 P ArsC family
MGECLEDA_01819 1.4e-68 S Protein of unknown function (DUF1722)
MGECLEDA_01820 8.9e-113 GM epimerase
MGECLEDA_01821 0.0 CP_1020 S Zinc finger, swim domain protein
MGECLEDA_01822 4.6e-81 K Bacterial regulatory proteins, tetR family
MGECLEDA_01823 6.2e-214 S membrane
MGECLEDA_01824 9.4e-15 K Bacterial regulatory proteins, tetR family
MGECLEDA_01825 1.9e-28 S Alpha/beta hydrolase of unknown function (DUF915)
MGECLEDA_01826 8.4e-13 S Alpha/beta hydrolase of unknown function (DUF915)
MGECLEDA_01827 8e-28 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_01828 3e-113 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
MGECLEDA_01829 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
MGECLEDA_01830 1.3e-128 K Helix-turn-helix domain, rpiR family
MGECLEDA_01831 4.1e-161 S Alpha beta hydrolase
MGECLEDA_01832 6.2e-114 GM NmrA-like family
MGECLEDA_01833 9.8e-79 S Uncharacterized protein conserved in bacteria (DUF2255)
MGECLEDA_01834 1.6e-160 K Transcriptional regulator
MGECLEDA_01835 8.7e-173 C nadph quinone reductase
MGECLEDA_01836 2.8e-14 S Alpha beta hydrolase
MGECLEDA_01837 5.7e-269 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MGECLEDA_01838 1.2e-103 desR K helix_turn_helix, Lux Regulon
MGECLEDA_01839 8.2e-207 desK 2.7.13.3 T Histidine kinase
MGECLEDA_01840 4.5e-135 yvfS V ABC-2 type transporter
MGECLEDA_01841 2.6e-158 yvfR V ABC transporter
MGECLEDA_01843 6.6e-81 K Acetyltransferase (GNAT) domain
MGECLEDA_01844 6.2e-73 K MarR family
MGECLEDA_01845 1e-114 S Psort location CytoplasmicMembrane, score
MGECLEDA_01846 2.6e-12 yjdF S Protein of unknown function (DUF2992)
MGECLEDA_01847 3.9e-162 V ABC transporter, ATP-binding protein
MGECLEDA_01848 9.8e-127 S ABC-2 family transporter protein
MGECLEDA_01849 1.1e-197
MGECLEDA_01850 3.5e-202
MGECLEDA_01851 4.8e-165 ytrB V ABC transporter, ATP-binding protein
MGECLEDA_01852 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
MGECLEDA_01853 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MGECLEDA_01854 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MGECLEDA_01855 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MGECLEDA_01856 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MGECLEDA_01857 3.4e-146 recO L Involved in DNA repair and RecF pathway recombination
MGECLEDA_01858 7.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MGECLEDA_01859 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MGECLEDA_01860 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MGECLEDA_01861 5.8e-180 phoH T phosphate starvation-inducible protein PhoH
MGECLEDA_01862 2.6e-71 yqeY S YqeY-like protein
MGECLEDA_01863 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MGECLEDA_01864 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MGECLEDA_01865 1.7e-128 C Enoyl-(Acyl carrier protein) reductase
MGECLEDA_01866 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MGECLEDA_01867 2.9e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MGECLEDA_01868 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MGECLEDA_01869 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MGECLEDA_01870 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MGECLEDA_01871 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
MGECLEDA_01872 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MGECLEDA_01873 3.5e-165 yniA G Fructosamine kinase
MGECLEDA_01874 7.9e-114 3.1.3.18 J HAD-hyrolase-like
MGECLEDA_01875 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MGECLEDA_01876 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MGECLEDA_01877 3.7e-57
MGECLEDA_01878 1.4e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MGECLEDA_01879 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
MGECLEDA_01880 3.6e-114 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MGECLEDA_01881 1.4e-49
MGECLEDA_01882 1.4e-49
MGECLEDA_01883 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MGECLEDA_01884 8.8e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MGECLEDA_01885 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MGECLEDA_01886 2.5e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
MGECLEDA_01887 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MGECLEDA_01888 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
MGECLEDA_01889 4.4e-198 pbpX2 V Beta-lactamase
MGECLEDA_01890 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MGECLEDA_01891 0.0 dnaK O Heat shock 70 kDa protein
MGECLEDA_01892 3e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MGECLEDA_01893 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MGECLEDA_01894 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MGECLEDA_01895 1.2e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MGECLEDA_01896 9.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MGECLEDA_01897 5.3e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MGECLEDA_01898 7.7e-197 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MGECLEDA_01899 1.4e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MGECLEDA_01900 1e-93
MGECLEDA_01901 9.3e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MGECLEDA_01902 4.6e-266 ydiN 5.4.99.5 G Major Facilitator
MGECLEDA_01903 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MGECLEDA_01904 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MGECLEDA_01905 1.1e-47 ylxQ J ribosomal protein
MGECLEDA_01906 9.5e-49 ylxR K Protein of unknown function (DUF448)
MGECLEDA_01907 3.3e-217 nusA K Participates in both transcription termination and antitermination
MGECLEDA_01908 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
MGECLEDA_01909 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MGECLEDA_01910 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MGECLEDA_01911 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MGECLEDA_01912 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
MGECLEDA_01913 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MGECLEDA_01914 3.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MGECLEDA_01915 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MGECLEDA_01916 3.9e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MGECLEDA_01917 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
MGECLEDA_01918 4.7e-134 S Haloacid dehalogenase-like hydrolase
MGECLEDA_01919 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MGECLEDA_01920 2e-49 yazA L GIY-YIG catalytic domain protein
MGECLEDA_01921 2.4e-133 yabB 2.1.1.223 L Methyltransferase small domain
MGECLEDA_01922 1.2e-117 plsC 2.3.1.51 I Acyltransferase
MGECLEDA_01923 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
MGECLEDA_01924 2.9e-36 ynzC S UPF0291 protein
MGECLEDA_01925 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MGECLEDA_01926 3.2e-86
MGECLEDA_01927 6.7e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MGECLEDA_01928 1.1e-76
MGECLEDA_01929 3.5e-67
MGECLEDA_01930 3.4e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
MGECLEDA_01933 2.1e-08 S Short C-terminal domain
MGECLEDA_01934 4.6e-26 S Short C-terminal domain
MGECLEDA_01936 2.9e-43 L HTH-like domain
MGECLEDA_01937 1.1e-34 L transposase activity
MGECLEDA_01938 8.5e-61 L Belongs to the 'phage' integrase family
MGECLEDA_01941 1.6e-31
MGECLEDA_01942 2.3e-139 Q Methyltransferase
MGECLEDA_01943 8.5e-57 ybjQ S Belongs to the UPF0145 family
MGECLEDA_01944 7.2e-212 EGP Major facilitator Superfamily
MGECLEDA_01945 1.5e-103 K Helix-turn-helix domain
MGECLEDA_01946 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MGECLEDA_01947 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MGECLEDA_01948 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
MGECLEDA_01949 4e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MGECLEDA_01950 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MGECLEDA_01951 3.2e-46
MGECLEDA_01952 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MGECLEDA_01953 1.5e-135 fruR K DeoR C terminal sensor domain
MGECLEDA_01954 4.6e-171 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MGECLEDA_01955 1.9e-291 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
MGECLEDA_01956 1.8e-253 cpdA S Calcineurin-like phosphoesterase
MGECLEDA_01957 1.9e-264 cps4J S Polysaccharide biosynthesis protein
MGECLEDA_01958 1.7e-176 cps4I M Glycosyltransferase like family 2
MGECLEDA_01959 1.6e-233
MGECLEDA_01960 5e-190 cps4G M Glycosyltransferase Family 4
MGECLEDA_01961 2.7e-202 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
MGECLEDA_01962 7.9e-128 tuaA M Bacterial sugar transferase
MGECLEDA_01963 5.2e-178 cps4D 5.1.3.2 M RmlD substrate binding domain
MGECLEDA_01964 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
MGECLEDA_01965 7.3e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MGECLEDA_01966 2.9e-126 epsB M biosynthesis protein
MGECLEDA_01967 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MGECLEDA_01968 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MGECLEDA_01969 9.2e-270 glnPH2 P ABC transporter permease
MGECLEDA_01970 4.3e-22
MGECLEDA_01971 9.9e-73 S Iron-sulphur cluster biosynthesis
MGECLEDA_01972 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MGECLEDA_01973 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
MGECLEDA_01974 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MGECLEDA_01975 4.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MGECLEDA_01976 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MGECLEDA_01977 3.1e-159 S Tetratricopeptide repeat
MGECLEDA_01978 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MGECLEDA_01979 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MGECLEDA_01980 1.3e-192 mdtG EGP Major Facilitator Superfamily
MGECLEDA_01981 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MGECLEDA_01982 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
MGECLEDA_01983 4.8e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
MGECLEDA_01984 0.0 comEC S Competence protein ComEC
MGECLEDA_01985 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
MGECLEDA_01986 4.7e-126 comEA L Competence protein ComEA
MGECLEDA_01987 9.6e-197 ylbL T Belongs to the peptidase S16 family
MGECLEDA_01988 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MGECLEDA_01989 1.1e-101 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MGECLEDA_01990 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MGECLEDA_01991 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MGECLEDA_01992 1.6e-205 ftsW D Belongs to the SEDS family
MGECLEDA_01993 1.4e-292
MGECLEDA_01994 3.3e-258 ica2 GT2 M Glycosyl transferase family group 2
MGECLEDA_01995 1.2e-103
MGECLEDA_01996 1.1e-197
MGECLEDA_01997 0.0 typA T GTP-binding protein TypA
MGECLEDA_01998 6.3e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MGECLEDA_01999 3.3e-46 yktA S Belongs to the UPF0223 family
MGECLEDA_02000 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
MGECLEDA_02001 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
MGECLEDA_02002 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MGECLEDA_02003 4.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MGECLEDA_02004 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MGECLEDA_02005 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MGECLEDA_02006 1.6e-85
MGECLEDA_02007 3.1e-33 ykzG S Belongs to the UPF0356 family
MGECLEDA_02008 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MGECLEDA_02009 1.7e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MGECLEDA_02010 3.7e-28
MGECLEDA_02011 4.9e-157 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MGECLEDA_02012 4.1e-108 mltD CBM50 M NlpC P60 family protein
MGECLEDA_02013 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MGECLEDA_02014 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MGECLEDA_02015 1.6e-120 S Repeat protein
MGECLEDA_02016 1.6e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MGECLEDA_02017 5.5e-267 N domain, Protein
MGECLEDA_02018 3.7e-193 S Bacterial protein of unknown function (DUF916)
MGECLEDA_02019 2.3e-120 N WxL domain surface cell wall-binding
MGECLEDA_02020 2.6e-115 ktrA P domain protein
MGECLEDA_02021 1.3e-241 ktrB P Potassium uptake protein
MGECLEDA_02022 9.1e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MGECLEDA_02023 3.7e-57 XK27_04120 S Putative amino acid metabolism
MGECLEDA_02024 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
MGECLEDA_02025 3.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MGECLEDA_02026 4.6e-28
MGECLEDA_02027 6.6e-96 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MGECLEDA_02028 3.7e-190 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MGECLEDA_02029 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MGECLEDA_02030 1.2e-86 divIVA D DivIVA domain protein
MGECLEDA_02031 3.4e-146 ylmH S S4 domain protein
MGECLEDA_02032 1.2e-36 yggT S YGGT family
MGECLEDA_02033 9.6e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MGECLEDA_02034 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MGECLEDA_02035 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MGECLEDA_02036 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MGECLEDA_02037 7.7e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MGECLEDA_02038 6.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MGECLEDA_02039 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MGECLEDA_02040 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MGECLEDA_02041 7.5e-54 ftsL D Cell division protein FtsL
MGECLEDA_02042 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MGECLEDA_02043 1.9e-77 mraZ K Belongs to the MraZ family
MGECLEDA_02044 1.9e-62 S Protein of unknown function (DUF3397)
MGECLEDA_02045 4.2e-175 corA P CorA-like Mg2+ transporter protein
MGECLEDA_02046 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MGECLEDA_02047 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MGECLEDA_02048 3.1e-113 ywnB S NAD(P)H-binding
MGECLEDA_02049 2.8e-209 brnQ U Component of the transport system for branched-chain amino acids
MGECLEDA_02050 5.5e-30 3.4.13.21, 3.4.15.6 E Belongs to the peptidase S51 family
MGECLEDA_02051 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
MGECLEDA_02052 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MGECLEDA_02053 4.3e-206 XK27_05220 S AI-2E family transporter
MGECLEDA_02054 2.5e-56 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MGECLEDA_02055 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MGECLEDA_02056 5.1e-116 cutC P Participates in the control of copper homeostasis
MGECLEDA_02057 7.5e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MGECLEDA_02058 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MGECLEDA_02059 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
MGECLEDA_02060 3.6e-114 yjbH Q Thioredoxin
MGECLEDA_02061 0.0 pepF E oligoendopeptidase F
MGECLEDA_02062 8.4e-204 coiA 3.6.4.12 S Competence protein
MGECLEDA_02063 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MGECLEDA_02064 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MGECLEDA_02065 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
MGECLEDA_02066 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MGECLEDA_02076 5.5e-08
MGECLEDA_02087 1e-44
MGECLEDA_02088 1.6e-75 yugI 5.3.1.9 J general stress protein
MGECLEDA_02089 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MGECLEDA_02090 3e-119 dedA S SNARE-like domain protein
MGECLEDA_02091 4.6e-117 S Protein of unknown function (DUF1461)
MGECLEDA_02092 3.4e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MGECLEDA_02093 1.5e-80 yutD S Protein of unknown function (DUF1027)
MGECLEDA_02094 8.7e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MGECLEDA_02095 4.4e-117 S Calcineurin-like phosphoesterase
MGECLEDA_02096 5.6e-253 cycA E Amino acid permease
MGECLEDA_02097 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MGECLEDA_02098 1.4e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
MGECLEDA_02100 4.5e-88 S Prokaryotic N-terminal methylation motif
MGECLEDA_02101 8.6e-20
MGECLEDA_02102 3.2e-83 gspG NU general secretion pathway protein
MGECLEDA_02103 5.5e-43 comGC U competence protein ComGC
MGECLEDA_02104 1.9e-189 comGB NU type II secretion system
MGECLEDA_02105 5.6e-175 comGA NU Type II IV secretion system protein
MGECLEDA_02106 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MGECLEDA_02107 8.3e-131 yebC K Transcriptional regulatory protein
MGECLEDA_02108 1.6e-49 S DsrE/DsrF-like family
MGECLEDA_02109 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
MGECLEDA_02110 1.9e-181 ccpA K catabolite control protein A
MGECLEDA_02111 6.3e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MGECLEDA_02112 1.1e-80 K helix_turn_helix, mercury resistance
MGECLEDA_02113 2.8e-56
MGECLEDA_02114 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MGECLEDA_02115 7.5e-158 ykuT M mechanosensitive ion channel
MGECLEDA_02116 1.1e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MGECLEDA_02117 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MGECLEDA_02118 6.5e-87 ykuL S (CBS) domain
MGECLEDA_02119 1.2e-94 S Phosphoesterase
MGECLEDA_02120 4e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MGECLEDA_02121 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MGECLEDA_02122 7.6e-126 yslB S Protein of unknown function (DUF2507)
MGECLEDA_02123 1.6e-51 trxA O Belongs to the thioredoxin family
MGECLEDA_02124 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MGECLEDA_02125 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MGECLEDA_02126 1.6e-48 yrzB S Belongs to the UPF0473 family
MGECLEDA_02127 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MGECLEDA_02128 2.4e-43 yrzL S Belongs to the UPF0297 family
MGECLEDA_02129 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MGECLEDA_02130 7.1e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MGECLEDA_02131 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MGECLEDA_02132 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MGECLEDA_02133 6.3e-29 yajC U Preprotein translocase
MGECLEDA_02134 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MGECLEDA_02135 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MGECLEDA_02136 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MGECLEDA_02137 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MGECLEDA_02138 2.7e-91
MGECLEDA_02139 0.0 S Bacterial membrane protein YfhO
MGECLEDA_02140 1.3e-72
MGECLEDA_02141 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MGECLEDA_02142 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MGECLEDA_02143 2.7e-154 ymdB S YmdB-like protein
MGECLEDA_02144 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
MGECLEDA_02145 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MGECLEDA_02146 7.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
MGECLEDA_02147 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MGECLEDA_02148 5.7e-110 ymfM S Helix-turn-helix domain
MGECLEDA_02149 2.9e-251 ymfH S Peptidase M16
MGECLEDA_02150 6.5e-232 ymfF S Peptidase M16 inactive domain protein
MGECLEDA_02151 1e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
MGECLEDA_02152 1.5e-155 aatB ET ABC transporter substrate-binding protein
MGECLEDA_02153 1.3e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MGECLEDA_02154 4.6e-109 glnP P ABC transporter permease
MGECLEDA_02155 1.2e-146 minD D Belongs to the ParA family
MGECLEDA_02156 1.4e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MGECLEDA_02157 1.2e-88 mreD M rod shape-determining protein MreD
MGECLEDA_02158 2.6e-144 mreC M Involved in formation and maintenance of cell shape
MGECLEDA_02159 2.8e-161 mreB D cell shape determining protein MreB
MGECLEDA_02160 1.3e-116 radC L DNA repair protein
MGECLEDA_02161 4.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MGECLEDA_02162 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MGECLEDA_02163 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MGECLEDA_02164 6.8e-234 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MGECLEDA_02165 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MGECLEDA_02166 1.7e-218 iscS2 2.8.1.7 E Aminotransferase class V
MGECLEDA_02167 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MGECLEDA_02168 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
MGECLEDA_02169 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MGECLEDA_02170 5.2e-113 yktB S Belongs to the UPF0637 family
MGECLEDA_02171 2.5e-80 yueI S Protein of unknown function (DUF1694)
MGECLEDA_02172 2e-109 S Protein of unknown function (DUF1648)
MGECLEDA_02173 8.6e-44 czrA K Helix-turn-helix domain
MGECLEDA_02174 9.6e-231 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MGECLEDA_02175 9.2e-42 2.7.1.191 G PTS system fructose IIA component
MGECLEDA_02176 2.7e-104 G PTS system mannose fructose sorbose family IID component
MGECLEDA_02177 3.6e-103 G PTS system sorbose-specific iic component
MGECLEDA_02178 6e-66 2.7.1.191 G PTS system sorbose subfamily IIB component
MGECLEDA_02179 2.7e-95 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
MGECLEDA_02180 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MGECLEDA_02181 8e-238 rarA L recombination factor protein RarA
MGECLEDA_02182 1.5e-38
MGECLEDA_02183 6.2e-82 usp6 T universal stress protein
MGECLEDA_02184 4.5e-08 bla2 3.5.2.6 V Beta-lactamase enzyme family
MGECLEDA_02185 8e-180 bla2 3.5.2.6 V Beta-lactamase enzyme family
MGECLEDA_02186 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MGECLEDA_02187 5.1e-295 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MGECLEDA_02188 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MGECLEDA_02189 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MGECLEDA_02190 6e-177 S Protein of unknown function (DUF2785)
MGECLEDA_02191 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
MGECLEDA_02192 6.5e-148 metQ M Belongs to the nlpA lipoprotein family
MGECLEDA_02193 1.4e-111 metI U ABC transporter permease
MGECLEDA_02194 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MGECLEDA_02195 3.6e-48 gcsH2 E glycine cleavage
MGECLEDA_02196 9.3e-220 rodA D Belongs to the SEDS family
MGECLEDA_02197 3.3e-33 S Protein of unknown function (DUF2969)
MGECLEDA_02198 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MGECLEDA_02199 2.7e-180 mbl D Cell shape determining protein MreB Mrl
MGECLEDA_02200 2.1e-102 J Acetyltransferase (GNAT) domain
MGECLEDA_02201 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MGECLEDA_02202 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MGECLEDA_02203 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MGECLEDA_02204 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MGECLEDA_02205 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MGECLEDA_02206 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MGECLEDA_02207 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MGECLEDA_02208 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MGECLEDA_02209 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
MGECLEDA_02210 1e-232 pyrP F Permease
MGECLEDA_02211 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MGECLEDA_02212 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MGECLEDA_02213 6.9e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MGECLEDA_02214 1e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MGECLEDA_02215 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MGECLEDA_02216 3.5e-108 tdk 2.7.1.21 F thymidine kinase
MGECLEDA_02217 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MGECLEDA_02218 1.7e-136 cobQ S glutamine amidotransferase
MGECLEDA_02219 9.8e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
MGECLEDA_02220 6.9e-192 ampC V Beta-lactamase
MGECLEDA_02221 5.2e-29
MGECLEDA_02222 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MGECLEDA_02223 1.9e-58
MGECLEDA_02224 5.3e-125
MGECLEDA_02225 0.0 yfiC V ABC transporter
MGECLEDA_02226 4.8e-311 ycfI V ABC transporter, ATP-binding protein
MGECLEDA_02227 3.3e-65 S Protein of unknown function (DUF1093)
MGECLEDA_02228 1.4e-134 yxkH G Polysaccharide deacetylase
MGECLEDA_02229 1.2e-27 hol S Bacteriophage holin
MGECLEDA_02230 1.6e-36 S Haemolysin XhlA
MGECLEDA_02231 8.4e-183 M hydrolase, family 25
MGECLEDA_02232 1.8e-08 S Phage uncharacterised protein (Phage_XkdX)
MGECLEDA_02235 5.5e-83 S Calcineurin-like phosphoesterase
MGECLEDA_02238 1.3e-170 M Prophage endopeptidase tail
MGECLEDA_02239 1.6e-139 S Phage tail protein
MGECLEDA_02241 1.3e-246 D NLP P60 protein
MGECLEDA_02243 5.8e-70 S Phage tail assembly chaperone protein, TAC
MGECLEDA_02244 5.4e-97
MGECLEDA_02245 5.3e-47
MGECLEDA_02246 1.5e-62
MGECLEDA_02247 3.8e-38
MGECLEDA_02248 7.4e-51 S Phage gp6-like head-tail connector protein
MGECLEDA_02249 1.1e-171 S Phage major capsid protein E
MGECLEDA_02250 2.6e-43
MGECLEDA_02251 4.5e-59 S Domain of unknown function (DUF4355)
MGECLEDA_02252 9.4e-132 S Phage Mu protein F like protein
MGECLEDA_02253 6.8e-272 S Phage portal protein, SPP1 Gp6-like
MGECLEDA_02254 1.2e-135 ps334 S Terminase-like family
MGECLEDA_02255 9.6e-57 S Terminase small subunit
MGECLEDA_02256 6e-11
MGECLEDA_02258 2.3e-17
MGECLEDA_02262 1.8e-14
MGECLEDA_02263 8.2e-11 S YopX protein
MGECLEDA_02266 5.3e-14
MGECLEDA_02269 9.1e-65 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MGECLEDA_02270 6.2e-64
MGECLEDA_02271 1.6e-94
MGECLEDA_02272 7e-49
MGECLEDA_02273 1.6e-147 3.1.3.16 L DnaD domain protein
MGECLEDA_02275 5.1e-76 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
MGECLEDA_02276 6.3e-79 recT L RecT family
MGECLEDA_02277 2.5e-70
MGECLEDA_02278 5.8e-11 S Domain of unknown function (DUF1508)
MGECLEDA_02279 6.1e-80
MGECLEDA_02280 2.2e-53
MGECLEDA_02283 5.7e-17 K sequence-specific DNA binding
MGECLEDA_02284 9.4e-10 E peptidase
MGECLEDA_02286 8.5e-11 S DNA/RNA non-specific endonuclease
MGECLEDA_02289 5.9e-44 S Domain of unknown function (DUF5067)
MGECLEDA_02290 1.6e-52
MGECLEDA_02294 1.4e-49
MGECLEDA_02296 1.8e-217 int L Belongs to the 'phage' integrase family
MGECLEDA_02298 8.9e-30
MGECLEDA_02300 1.4e-267 S Virulence-associated protein E
MGECLEDA_02301 4.1e-147 L DNA replication protein
MGECLEDA_02302 4.7e-29
MGECLEDA_02304 1.9e-07
MGECLEDA_02306 4.7e-10 K sequence-specific DNA binding
MGECLEDA_02307 2.7e-224 sip L Belongs to the 'phage' integrase family
MGECLEDA_02309 9.3e-57
MGECLEDA_02310 2.1e-39 S Phage gp6-like head-tail connector protein
MGECLEDA_02311 2.2e-258 S Caudovirus prohead serine protease
MGECLEDA_02312 2.7e-202 S Phage portal protein
MGECLEDA_02314 0.0 terL S overlaps another CDS with the same product name
MGECLEDA_02315 2.3e-81 terS L overlaps another CDS with the same product name
MGECLEDA_02316 9.8e-70 L Phage-associated protein
MGECLEDA_02317 4.8e-49 S head-tail joining protein
MGECLEDA_02319 2.3e-72
MGECLEDA_02320 2e-38
MGECLEDA_02321 1.4e-43
MGECLEDA_02322 7.3e-83 K MarR family
MGECLEDA_02323 0.0 bztC D nuclear chromosome segregation
MGECLEDA_02324 1.3e-299 M MucBP domain
MGECLEDA_02325 2.7e-16
MGECLEDA_02326 7.2e-17
MGECLEDA_02327 5.2e-15
MGECLEDA_02328 1.1e-18
MGECLEDA_02329 1.6e-16
MGECLEDA_02330 1.6e-16
MGECLEDA_02331 1.6e-16
MGECLEDA_02332 1.9e-18
MGECLEDA_02333 1.6e-16
MGECLEDA_02334 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
MGECLEDA_02335 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MGECLEDA_02336 0.0 macB3 V ABC transporter, ATP-binding protein
MGECLEDA_02337 6.8e-24
MGECLEDA_02338 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
MGECLEDA_02339 9.7e-155 glcU U sugar transport
MGECLEDA_02340 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
MGECLEDA_02341 2.9e-287 yclK 2.7.13.3 T Histidine kinase
MGECLEDA_02342 3.1e-133 K response regulator
MGECLEDA_02343 3e-243 XK27_08635 S UPF0210 protein
MGECLEDA_02344 8.9e-38 gcvR T Belongs to the UPF0237 family
MGECLEDA_02345 2e-169 EG EamA-like transporter family
MGECLEDA_02347 7.7e-92 S ECF-type riboflavin transporter, S component
MGECLEDA_02348 8.6e-48
MGECLEDA_02349 9.8e-214 yceI EGP Major facilitator Superfamily
MGECLEDA_02350 5.5e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
MGECLEDA_02351 3.8e-23
MGECLEDA_02353 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
MGECLEDA_02354 2.8e-173 ykfC 3.4.14.13 M NlpC/P60 family
MGECLEDA_02355 6.6e-81 K AsnC family
MGECLEDA_02356 2e-35
MGECLEDA_02357 5.1e-34
MGECLEDA_02358 7.8e-219 2.7.7.65 T diguanylate cyclase
MGECLEDA_02359 7.8e-296 S ABC transporter, ATP-binding protein
MGECLEDA_02360 2e-106 3.2.2.20 K acetyltransferase
MGECLEDA_02361 5.8e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MGECLEDA_02362 2.7e-39
MGECLEDA_02363 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
MGECLEDA_02364 3.4e-188 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MGECLEDA_02365 5e-162 degV S Uncharacterised protein, DegV family COG1307
MGECLEDA_02366 7.3e-231 hom1 1.1.1.3 E Homoserine dehydrogenase
MGECLEDA_02367 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MGECLEDA_02368 3.6e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MGECLEDA_02369 1.4e-176 XK27_08835 S ABC transporter
MGECLEDA_02370 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MGECLEDA_02371 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
MGECLEDA_02372 3.7e-257 npr 1.11.1.1 C NADH oxidase
MGECLEDA_02373 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MGECLEDA_02374 4.8e-137 terC P membrane
MGECLEDA_02375 2.4e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MGECLEDA_02376 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MGECLEDA_02377 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
MGECLEDA_02378 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MGECLEDA_02379 3.2e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MGECLEDA_02380 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MGECLEDA_02381 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MGECLEDA_02382 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MGECLEDA_02383 1.2e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MGECLEDA_02384 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MGECLEDA_02385 1.3e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MGECLEDA_02386 1.7e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
MGECLEDA_02387 1.8e-215 ysaA V RDD family
MGECLEDA_02388 9.9e-166 corA P CorA-like Mg2+ transporter protein
MGECLEDA_02389 2.1e-55 S Domain of unknown function (DU1801)
MGECLEDA_02390 5.9e-91 rmeB K transcriptional regulator, MerR family
MGECLEDA_02391 1.4e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
MGECLEDA_02392 8.6e-98 J glyoxalase III activity
MGECLEDA_02393 8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MGECLEDA_02394 1.1e-186 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MGECLEDA_02395 3.7e-34
MGECLEDA_02396 9.2e-112 S Protein of unknown function (DUF1211)
MGECLEDA_02397 0.0 ydgH S MMPL family
MGECLEDA_02398 3.6e-288 M domain protein
MGECLEDA_02399 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
MGECLEDA_02400 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MGECLEDA_02401 0.0 glpQ 3.1.4.46 C phosphodiesterase
MGECLEDA_02402 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MGECLEDA_02403 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
MGECLEDA_02404 3.6e-168 S Polyphosphate kinase 2 (PPK2)
MGECLEDA_02405 2.7e-97 drgA C Nitroreductase family
MGECLEDA_02406 3.1e-178 iunH2 3.2.2.1 F nucleoside hydrolase
MGECLEDA_02407 5.2e-151 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MGECLEDA_02408 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
MGECLEDA_02409 2.3e-157 ccpB 5.1.1.1 K lacI family
MGECLEDA_02410 8.1e-117 K Helix-turn-helix domain, rpiR family
MGECLEDA_02412 7.4e-175 S Oxidoreductase family, NAD-binding Rossmann fold
MGECLEDA_02413 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
MGECLEDA_02414 0.0 yjcE P Sodium proton antiporter
MGECLEDA_02415 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MGECLEDA_02416 3.7e-107 pncA Q Isochorismatase family
MGECLEDA_02417 2.7e-132
MGECLEDA_02418 5.1e-125 skfE V ABC transporter
MGECLEDA_02419 4.7e-64 yvoA_1 K Transcriptional regulator, GntR family
MGECLEDA_02420 1.2e-45 S Enterocin A Immunity
MGECLEDA_02421 7e-175 D Alpha beta
MGECLEDA_02422 0.0 pepF2 E Oligopeptidase F
MGECLEDA_02423 1.3e-72 K Transcriptional regulator
MGECLEDA_02424 3e-164
MGECLEDA_02425 1.3e-57
MGECLEDA_02426 2.2e-47
MGECLEDA_02427 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MGECLEDA_02428 1.2e-67
MGECLEDA_02429 8.4e-145 yjfP S Dienelactone hydrolase family
MGECLEDA_02430 6.6e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
MGECLEDA_02431 9.3e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MGECLEDA_02432 5.2e-47
MGECLEDA_02433 6.3e-45
MGECLEDA_02434 5e-82 yybC S Protein of unknown function (DUF2798)
MGECLEDA_02435 1.7e-73
MGECLEDA_02436 4e-60
MGECLEDA_02437 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
MGECLEDA_02438 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
MGECLEDA_02439 4.7e-79 uspA T universal stress protein
MGECLEDA_02440 8.7e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MGECLEDA_02441 5.7e-20
MGECLEDA_02442 4.2e-44 S zinc-ribbon domain
MGECLEDA_02443 3.7e-69 S response to antibiotic
MGECLEDA_02444 1.7e-48 K Cro/C1-type HTH DNA-binding domain
MGECLEDA_02445 5.6e-21 S Protein of unknown function (DUF2929)
MGECLEDA_02446 9.4e-225 lsgC M Glycosyl transferases group 1
MGECLEDA_02447 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MGECLEDA_02448 4.8e-162 S Putative esterase
MGECLEDA_02449 2.4e-130 gntR2 K Transcriptional regulator
MGECLEDA_02450 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MGECLEDA_02451 5.8e-138
MGECLEDA_02452 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MGECLEDA_02453 5.5e-138 rrp8 K LytTr DNA-binding domain
MGECLEDA_02454 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
MGECLEDA_02455 7.7e-61
MGECLEDA_02456 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
MGECLEDA_02457 4.4e-58
MGECLEDA_02458 1.2e-239 yhdP S Transporter associated domain
MGECLEDA_02459 4.9e-87 nrdI F Belongs to the NrdI family
MGECLEDA_02460 2.9e-269 yjcE P Sodium proton antiporter
MGECLEDA_02461 1.8e-212 yttB EGP Major facilitator Superfamily
MGECLEDA_02462 2.5e-62 K helix_turn_helix, mercury resistance
MGECLEDA_02463 1.8e-173 C Zinc-binding dehydrogenase
MGECLEDA_02464 8.5e-57 S SdpI/YhfL protein family
MGECLEDA_02465 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MGECLEDA_02466 5.5e-261 gabR K Bacterial regulatory proteins, gntR family
MGECLEDA_02467 2.1e-216 patA 2.6.1.1 E Aminotransferase
MGECLEDA_02468 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MGECLEDA_02469 3e-18
MGECLEDA_02470 1.7e-126 S membrane transporter protein
MGECLEDA_02471 1.9e-161 mleR K LysR family
MGECLEDA_02472 5.6e-115 ylbE GM NAD(P)H-binding
MGECLEDA_02473 8.2e-96 wecD K Acetyltransferase (GNAT) family
MGECLEDA_02474 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MGECLEDA_02475 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MGECLEDA_02476 4.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
MGECLEDA_02477 1.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MGECLEDA_02478 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MGECLEDA_02479 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MGECLEDA_02480 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MGECLEDA_02481 1.5e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MGECLEDA_02482 1.5e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MGECLEDA_02483 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MGECLEDA_02484 3.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MGECLEDA_02485 3.9e-298 pucR QT Purine catabolism regulatory protein-like family
MGECLEDA_02486 3.5e-236 pbuX F xanthine permease
MGECLEDA_02487 2.4e-221 pbuG S Permease family
MGECLEDA_02488 3.9e-162 GM NmrA-like family
MGECLEDA_02489 6.5e-156 T EAL domain
MGECLEDA_02490 2.6e-94
MGECLEDA_02491 1.2e-252 pgaC GT2 M Glycosyl transferase
MGECLEDA_02492 6.9e-124 2.1.1.14 E Methionine synthase
MGECLEDA_02493 6.4e-216 purD 6.3.4.13 F Belongs to the GARS family
MGECLEDA_02494 7.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MGECLEDA_02495 2.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MGECLEDA_02496 9.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MGECLEDA_02497 1.1e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MGECLEDA_02498 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MGECLEDA_02499 5.8e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MGECLEDA_02500 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MGECLEDA_02501 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MGECLEDA_02502 6.3e-210 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MGECLEDA_02503 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MGECLEDA_02504 1.5e-223 XK27_09615 1.3.5.4 S reductase
MGECLEDA_02505 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
MGECLEDA_02506 4.9e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
MGECLEDA_02507 4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
MGECLEDA_02508 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
MGECLEDA_02509 3.7e-148 S Alpha/beta hydrolase of unknown function (DUF915)
MGECLEDA_02510 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
MGECLEDA_02511 1.7e-139 cysA V ABC transporter, ATP-binding protein
MGECLEDA_02512 0.0 V FtsX-like permease family
MGECLEDA_02513 8e-42
MGECLEDA_02514 7.9e-61 gntR1 K Transcriptional regulator, GntR family
MGECLEDA_02515 6.9e-164 V ABC transporter, ATP-binding protein
MGECLEDA_02516 2.9e-148
MGECLEDA_02517 6.7e-81 uspA T universal stress protein
MGECLEDA_02518 1.2e-35
MGECLEDA_02519 4.2e-71 gtcA S Teichoic acid glycosylation protein
MGECLEDA_02520 1.1e-88
MGECLEDA_02521 2.1e-49
MGECLEDA_02523 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
MGECLEDA_02524 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
MGECLEDA_02525 1.6e-117
MGECLEDA_02526 1.5e-52
MGECLEDA_02528 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MGECLEDA_02529 1.5e-280 thrC 4.2.3.1 E Threonine synthase
MGECLEDA_02530 8.5e-145 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
MGECLEDA_02531 9.8e-11 mcbG S Pentapeptide repeats (8 copies)
MGECLEDA_02532 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MGECLEDA_02533 3.1e-101 3.6.1.13 L Belongs to the Nudix hydrolase family
MGECLEDA_02534 5.1e-68 FG Scavenger mRNA decapping enzyme C-term binding
MGECLEDA_02535 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
MGECLEDA_02536 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
MGECLEDA_02537 3.8e-212 S Bacterial protein of unknown function (DUF871)
MGECLEDA_02538 1.4e-231 S Sterol carrier protein domain
MGECLEDA_02539 3.6e-88 niaR S 3H domain
MGECLEDA_02540 8.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MGECLEDA_02541 1.3e-117 K Transcriptional regulator
MGECLEDA_02542 3.2e-154 V ABC transporter
MGECLEDA_02543 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
MGECLEDA_02544 1.1e-245 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MGECLEDA_02545 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MGECLEDA_02546 9.5e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MGECLEDA_02547 5.1e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MGECLEDA_02548 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MGECLEDA_02549 1.2e-129 gntR K UTRA
MGECLEDA_02550 2.6e-140 epsV 2.7.8.12 S glycosyl transferase family 2
MGECLEDA_02551 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MGECLEDA_02552 1.8e-81
MGECLEDA_02553 9.8e-152 S hydrolase
MGECLEDA_02554 6.5e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MGECLEDA_02555 1.9e-151 EG EamA-like transporter family
MGECLEDA_02556 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MGECLEDA_02557 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MGECLEDA_02558 5.9e-233
MGECLEDA_02559 1.1e-77 fld C Flavodoxin
MGECLEDA_02560 0.0 M Bacterial Ig-like domain (group 3)
MGECLEDA_02561 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
MGECLEDA_02562 2.7e-32
MGECLEDA_02563 8.3e-129 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
MGECLEDA_02564 1.1e-267 ycaM E amino acid
MGECLEDA_02565 7.9e-79 K Winged helix DNA-binding domain
MGECLEDA_02566 3.3e-166 S Oxidoreductase, aldo keto reductase family protein
MGECLEDA_02567 5.7e-163 akr5f 1.1.1.346 S reductase
MGECLEDA_02568 4.6e-163 K Transcriptional regulator
MGECLEDA_02570 1.8e-84 hmpT S Pfam:DUF3816
MGECLEDA_02571 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MGECLEDA_02572 3.9e-111
MGECLEDA_02573 3.5e-148 M Glycosyl hydrolases family 25
MGECLEDA_02574 2e-143 yvpB S Peptidase_C39 like family
MGECLEDA_02575 1.1e-92 yueI S Protein of unknown function (DUF1694)
MGECLEDA_02576 1.6e-115 S Protein of unknown function (DUF554)
MGECLEDA_02577 2.6e-149 KT helix_turn_helix, mercury resistance
MGECLEDA_02578 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MGECLEDA_02579 6.6e-95 S Protein of unknown function (DUF1440)
MGECLEDA_02580 2e-173 hrtB V ABC transporter permease
MGECLEDA_02581 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MGECLEDA_02582 1.4e-90 2.7.7.65 T phosphorelay sensor kinase activity
MGECLEDA_02583 1.8e-184 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MGECLEDA_02584 8.1e-99 1.5.1.3 H RibD C-terminal domain
MGECLEDA_02585 1.8e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MGECLEDA_02586 7.5e-118 S Membrane
MGECLEDA_02587 8e-155 mleP3 S Membrane transport protein
MGECLEDA_02588 5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
MGECLEDA_02589 3.8e-189 ynfM EGP Major facilitator Superfamily
MGECLEDA_02590 3.1e-71 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MGECLEDA_02591 1.4e-33 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MGECLEDA_02592 1.1e-270 lmrB EGP Major facilitator Superfamily
MGECLEDA_02593 3.1e-76 S Domain of unknown function (DUF4811)
MGECLEDA_02594 1.8e-101 rimL J Acetyltransferase (GNAT) domain
MGECLEDA_02595 9.3e-173 S Conserved hypothetical protein 698
MGECLEDA_02596 3.7e-151 rlrG K Transcriptional regulator
MGECLEDA_02597 2.4e-297 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
MGECLEDA_02598 1.8e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
MGECLEDA_02599 1.6e-33 lytE M LysM domain protein
MGECLEDA_02600 1.6e-53 lytE M LysM domain
MGECLEDA_02601 4e-92 ogt 2.1.1.63 L Methyltransferase
MGECLEDA_02602 3.6e-168 natA S ABC transporter, ATP-binding protein
MGECLEDA_02603 1.2e-211 natB CP ABC-2 family transporter protein
MGECLEDA_02604 1e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MGECLEDA_02605 6.6e-56 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
MGECLEDA_02606 4.6e-75 yphH S Cupin domain
MGECLEDA_02607 4.4e-79 K transcriptional regulator, MerR family
MGECLEDA_02608 2.3e-237 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MGECLEDA_02609 0.0 ylbB V ABC transporter permease
MGECLEDA_02610 7.5e-121 macB V ABC transporter, ATP-binding protein
MGECLEDA_02612 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MGECLEDA_02613 1.4e-99 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MGECLEDA_02614 4.2e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MGECLEDA_02615 1.1e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MGECLEDA_02616 2.4e-83
MGECLEDA_02617 7.3e-86 yvbK 3.1.3.25 K GNAT family
MGECLEDA_02618 7e-37
MGECLEDA_02619 8.2e-48
MGECLEDA_02620 3.4e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
MGECLEDA_02621 3.8e-63 S Domain of unknown function (DUF4440)
MGECLEDA_02622 1.3e-157 K LysR substrate binding domain
MGECLEDA_02623 6.4e-105 GM NAD(P)H-binding
MGECLEDA_02624 2e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MGECLEDA_02625 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
MGECLEDA_02627 6.1e-76 T Belongs to the universal stress protein A family
MGECLEDA_02628 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
MGECLEDA_02629 8.9e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MGECLEDA_02630 1.7e-62
MGECLEDA_02631 3e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MGECLEDA_02632 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
MGECLEDA_02633 1.9e-102 M Protein of unknown function (DUF3737)
MGECLEDA_02634 2.6e-194 C Aldo/keto reductase family
MGECLEDA_02636 0.0 mdlB V ABC transporter
MGECLEDA_02637 0.0 mdlA V ABC transporter
MGECLEDA_02638 1.1e-245 EGP Major facilitator Superfamily
MGECLEDA_02640 6.2e-09
MGECLEDA_02641 1.5e-189 yhgE V domain protein
MGECLEDA_02642 1.1e-95 K Transcriptional regulator (TetR family)
MGECLEDA_02643 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
MGECLEDA_02644 8.8e-141 endA F DNA RNA non-specific endonuclease
MGECLEDA_02645 3.1e-98 speG J Acetyltransferase (GNAT) domain
MGECLEDA_02646 1.3e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
MGECLEDA_02647 4.5e-222 S CAAX protease self-immunity
MGECLEDA_02648 3.2e-308 ybiT S ABC transporter, ATP-binding protein
MGECLEDA_02649 5.3e-147 3.1.3.102, 3.1.3.104 S hydrolase
MGECLEDA_02650 0.0 S Predicted membrane protein (DUF2207)
MGECLEDA_02651 0.0 uvrA3 L excinuclease ABC
MGECLEDA_02652 1.1e-209 EGP Major facilitator Superfamily
MGECLEDA_02653 7.6e-174 ropB K Helix-turn-helix XRE-family like proteins
MGECLEDA_02654 4e-175 pepR1 3.4.11.5 I Releases the N-terminal proline from various substrates
MGECLEDA_02655 9.8e-250 puuP_1 E Amino acid permease
MGECLEDA_02656 1.7e-233 yxiO S Vacuole effluxer Atg22 like
MGECLEDA_02657 1.7e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
MGECLEDA_02658 2e-160 I alpha/beta hydrolase fold
MGECLEDA_02659 4.8e-131 treR K UTRA
MGECLEDA_02660 1.9e-238
MGECLEDA_02661 5.6e-39 S Cytochrome B5
MGECLEDA_02662 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MGECLEDA_02663 3.1e-217 2.7.7.65 T Diguanylate cyclase, GGDEF domain
MGECLEDA_02664 3.1e-127 yliE T EAL domain
MGECLEDA_02665 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MGECLEDA_02666 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MGECLEDA_02667 2e-80
MGECLEDA_02668 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MGECLEDA_02669 5.8e-191 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MGECLEDA_02670 7.6e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MGECLEDA_02671 4.9e-22
MGECLEDA_02672 1e-50
MGECLEDA_02673 1.1e-164 K LysR substrate binding domain
MGECLEDA_02674 2.4e-243 P Sodium:sulfate symporter transmembrane region
MGECLEDA_02675 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MGECLEDA_02676 2.8e-263 S response to antibiotic
MGECLEDA_02677 2.8e-134 S zinc-ribbon domain
MGECLEDA_02679 3.2e-37
MGECLEDA_02680 8.2e-134 aroD S Alpha/beta hydrolase family
MGECLEDA_02681 5.2e-177 S Phosphotransferase system, EIIC
MGECLEDA_02682 2.8e-268 I acetylesterase activity
MGECLEDA_02683 3.3e-224 sdrF M Collagen binding domain
MGECLEDA_02684 1.1e-159 yicL EG EamA-like transporter family
MGECLEDA_02685 4.4e-129 E lipolytic protein G-D-S-L family
MGECLEDA_02686 1.1e-177 4.1.1.52 S Amidohydrolase
MGECLEDA_02687 2.1e-111 K Transcriptional regulator C-terminal region
MGECLEDA_02688 1.4e-47 3.6.4.12 K HxlR-like helix-turn-helix
MGECLEDA_02689 2.3e-159 ypbG 2.7.1.2 GK ROK family
MGECLEDA_02690 0.0 lmrA 3.6.3.44 V ABC transporter
MGECLEDA_02691 2.9e-96 rmaB K Transcriptional regulator, MarR family
MGECLEDA_02692 5e-119 drgA C Nitroreductase family
MGECLEDA_02693 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
MGECLEDA_02694 8.1e-109 cmpC S ATPases associated with a variety of cellular activities
MGECLEDA_02695 2.4e-152 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
MGECLEDA_02696 3.5e-169 XK27_00670 S ABC transporter
MGECLEDA_02697 1e-260
MGECLEDA_02698 8.6e-63
MGECLEDA_02699 3.6e-188 S Cell surface protein
MGECLEDA_02700 3.4e-79 S WxL domain surface cell wall-binding
MGECLEDA_02701 4e-07 S WxL domain surface cell wall-binding
MGECLEDA_02702 2.4e-97 acuB S Domain in cystathionine beta-synthase and other proteins.
MGECLEDA_02703 3.3e-124 livF E ABC transporter
MGECLEDA_02704 1.8e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
MGECLEDA_02705 5.3e-141 livM E Branched-chain amino acid transport system / permease component
MGECLEDA_02706 6.5e-154 livH U Branched-chain amino acid transport system / permease component
MGECLEDA_02707 5.4e-212 livJ E Receptor family ligand binding region
MGECLEDA_02709 7e-33
MGECLEDA_02710 1.7e-113 zmp3 O Zinc-dependent metalloprotease
MGECLEDA_02711 2.8e-82 gtrA S GtrA-like protein
MGECLEDA_02712 6.1e-122 K Helix-turn-helix XRE-family like proteins
MGECLEDA_02713 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
MGECLEDA_02714 6.8e-72 T Belongs to the universal stress protein A family
MGECLEDA_02715 4e-46
MGECLEDA_02716 1.9e-116 S SNARE associated Golgi protein
MGECLEDA_02717 1.9e-47 K Transcriptional regulator, ArsR family
MGECLEDA_02718 1.2e-95 cadD P Cadmium resistance transporter
MGECLEDA_02719 0.0 yhcA V ABC transporter, ATP-binding protein
MGECLEDA_02720 0.0 P Concanavalin A-like lectin/glucanases superfamily
MGECLEDA_02721 7.4e-64
MGECLEDA_02722 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
MGECLEDA_02723 3.6e-54
MGECLEDA_02724 2e-149 dicA K Helix-turn-helix domain
MGECLEDA_02725 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MGECLEDA_02726 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MGECLEDA_02727 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_02728 3.1e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MGECLEDA_02729 1.8e-184 1.1.1.219 GM Male sterility protein
MGECLEDA_02730 2.7e-76 K helix_turn_helix, mercury resistance
MGECLEDA_02731 2.3e-65 M LysM domain
MGECLEDA_02732 2.3e-95 M Lysin motif
MGECLEDA_02733 4.7e-108 S SdpI/YhfL protein family
MGECLEDA_02734 1.8e-54 nudA S ASCH
MGECLEDA_02735 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
MGECLEDA_02736 4.2e-92
MGECLEDA_02737 2e-120 tag 3.2.2.20 L Methyladenine glycosylase
MGECLEDA_02738 3.3e-219 T diguanylate cyclase
MGECLEDA_02739 1.2e-73 S Psort location Cytoplasmic, score
MGECLEDA_02740 1.8e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
MGECLEDA_02741 2.6e-166 K Bacterial regulatory helix-turn-helix protein, lysR family
MGECLEDA_02742 2e-73
MGECLEDA_02743 2.5e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MGECLEDA_02744 1.3e-175 C C4-dicarboxylate transmembrane transporter activity
MGECLEDA_02745 3e-116 GM NAD(P)H-binding
MGECLEDA_02746 2.6e-91 S Phosphatidylethanolamine-binding protein
MGECLEDA_02747 2.3e-77 yphH S Cupin domain
MGECLEDA_02748 2.4e-59 I sulfurtransferase activity
MGECLEDA_02749 2.5e-138 IQ reductase
MGECLEDA_02750 1.1e-116 GM NAD(P)H-binding
MGECLEDA_02751 1.2e-216 ykiI
MGECLEDA_02752 0.0 V ABC transporter
MGECLEDA_02753 3.6e-310 XK27_09600 V ABC transporter, ATP-binding protein
MGECLEDA_02754 3.5e-42
MGECLEDA_02755 2.7e-227 amd 3.5.1.47 E Peptidase family M20/M25/M40
MGECLEDA_02756 5e-162 IQ KR domain
MGECLEDA_02758 1.1e-69
MGECLEDA_02759 1.5e-144 K Helix-turn-helix XRE-family like proteins
MGECLEDA_02760 3.6e-266 yjeM E Amino Acid
MGECLEDA_02761 3.9e-66 lysM M LysM domain
MGECLEDA_02762 3.9e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
MGECLEDA_02763 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MGECLEDA_02764 0.0 ctpA 3.6.3.54 P P-type ATPase
MGECLEDA_02765 3.2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MGECLEDA_02766 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MGECLEDA_02767 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MGECLEDA_02768 6e-140 K Helix-turn-helix domain
MGECLEDA_02769 2.9e-38 S TfoX C-terminal domain
MGECLEDA_02770 3.5e-228 hpk9 2.7.13.3 T GHKL domain
MGECLEDA_02771 8.4e-263
MGECLEDA_02772 3.8e-75
MGECLEDA_02773 8e-183 S Cell surface protein
MGECLEDA_02774 1.7e-101 S WxL domain surface cell wall-binding
MGECLEDA_02775 1.7e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
MGECLEDA_02776 9.3e-68 S Iron-sulphur cluster biosynthesis
MGECLEDA_02777 6.6e-116 S GyrI-like small molecule binding domain
MGECLEDA_02778 4.3e-189 S Cell surface protein
MGECLEDA_02780 2e-101 S WxL domain surface cell wall-binding
MGECLEDA_02781 1.1e-62
MGECLEDA_02782 3.1e-218 NU Mycoplasma protein of unknown function, DUF285
MGECLEDA_02783 5.9e-117
MGECLEDA_02784 3e-116 S Haloacid dehalogenase-like hydrolase
MGECLEDA_02785 2e-61 K Transcriptional regulator, HxlR family
MGECLEDA_02786 4.9e-213 ytbD EGP Major facilitator Superfamily
MGECLEDA_02787 1.4e-94 M ErfK YbiS YcfS YnhG
MGECLEDA_02788 0.0 asnB 6.3.5.4 E Asparagine synthase
MGECLEDA_02789 1.7e-134 K LytTr DNA-binding domain
MGECLEDA_02790 3e-205 2.7.13.3 T GHKL domain
MGECLEDA_02791 7.9e-100 fadR K Bacterial regulatory proteins, tetR family
MGECLEDA_02792 1.4e-167 GM NmrA-like family
MGECLEDA_02793 2e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MGECLEDA_02794 0.0 M Glycosyl hydrolases family 25
MGECLEDA_02795 1e-47 S Domain of unknown function (DUF1905)
MGECLEDA_02796 8.3e-63 hxlR K HxlR-like helix-turn-helix
MGECLEDA_02797 9.8e-132 ydfG S KR domain
MGECLEDA_02798 4e-96 K Bacterial regulatory proteins, tetR family
MGECLEDA_02799 1.2e-191 1.1.1.219 GM Male sterility protein
MGECLEDA_02800 4.1e-101 S Protein of unknown function (DUF1211)
MGECLEDA_02801 1.5e-180 S Aldo keto reductase
MGECLEDA_02802 1.6e-253 yfjF U Sugar (and other) transporter
MGECLEDA_02803 7.4e-109 K Bacterial regulatory proteins, tetR family
MGECLEDA_02804 2e-169 fhuD P Periplasmic binding protein
MGECLEDA_02805 5.5e-144 fhuC 3.6.3.34 HP ABC transporter
MGECLEDA_02806 2.3e-176 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MGECLEDA_02807 3.9e-171 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MGECLEDA_02808 5.4e-92 K Bacterial regulatory proteins, tetR family
MGECLEDA_02809 1.3e-162 GM NmrA-like family
MGECLEDA_02810 2.5e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MGECLEDA_02811 1.3e-68 maa S transferase hexapeptide repeat
MGECLEDA_02812 9.2e-150 IQ Enoyl-(Acyl carrier protein) reductase
MGECLEDA_02813 2.3e-63 K helix_turn_helix, mercury resistance
MGECLEDA_02814 7.3e-283 pelX UW LPXTG-motif cell wall anchor domain protein
MGECLEDA_02815 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
MGECLEDA_02816 6.8e-174 S Bacterial protein of unknown function (DUF916)
MGECLEDA_02817 8.7e-83 S WxL domain surface cell wall-binding
MGECLEDA_02818 2.8e-157 NU Mycoplasma protein of unknown function, DUF285
MGECLEDA_02819 5e-53 NU Mycoplasma protein of unknown function, DUF285
MGECLEDA_02820 1.4e-116 K Bacterial regulatory proteins, tetR family
MGECLEDA_02821 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MGECLEDA_02822 3.5e-291 yjcE P Sodium proton antiporter
MGECLEDA_02823 1.5e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MGECLEDA_02824 1.6e-160 K LysR substrate binding domain
MGECLEDA_02825 5.8e-280 1.3.5.4 C FAD binding domain
MGECLEDA_02826 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
MGECLEDA_02827 2.2e-115 K UTRA
MGECLEDA_02828 4.4e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MGECLEDA_02829 1.6e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGECLEDA_02830 4.1e-65
MGECLEDA_02831 1.5e-11
MGECLEDA_02832 9.4e-41 4.1.1.44 S Carboxymuconolactone decarboxylase family
MGECLEDA_02833 1.3e-23 rmeD K helix_turn_helix, mercury resistance
MGECLEDA_02834 7.6e-64 S Protein of unknown function (DUF1093)
MGECLEDA_02835 1.5e-207 S Membrane
MGECLEDA_02836 2.1e-78 yobS K transcriptional regulator
MGECLEDA_02837 1.2e-144 S Alpha/beta hydrolase family
MGECLEDA_02838 2.3e-165 4.1.1.52 S Amidohydrolase
MGECLEDA_02839 2.5e-45 K HxlR-like helix-turn-helix
MGECLEDA_02840 3.6e-144 C Alcohol dehydrogenase GroES-like domain
MGECLEDA_02841 1.7e-204 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MGECLEDA_02843 2.5e-36 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MGECLEDA_02844 2.1e-101 M ErfK YbiS YcfS YnhG
MGECLEDA_02845 5.9e-112 akr5f 1.1.1.346 S reductase
MGECLEDA_02846 3.1e-107 GM NAD(P)H-binding
MGECLEDA_02847 3.2e-77 3.5.4.1 GM SnoaL-like domain
MGECLEDA_02848 3.6e-258 qacA EGP Fungal trichothecene efflux pump (TRI12)
MGECLEDA_02849 9.2e-65 S Domain of unknown function (DUF4440)
MGECLEDA_02850 2.4e-104 K Bacterial regulatory proteins, tetR family
MGECLEDA_02851 1.2e-20 L HTH-like domain
MGECLEDA_02852 3.6e-32 L Integrase core domain
MGECLEDA_02854 6.8e-33 L transposase activity
MGECLEDA_02855 3.9e-31
MGECLEDA_02856 1e-31 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MGECLEDA_02857 1.8e-76 S Reverse transcriptase (RNA-dependent DNA polymerase)
MGECLEDA_02858 3.1e-83 K IrrE N-terminal-like domain
MGECLEDA_02859 7.8e-10
MGECLEDA_02860 1.8e-140 L Phage integrase SAM-like domain
MGECLEDA_02861 1.1e-35 3.1.3.16 S Protein of unknown function (DUF1643)
MGECLEDA_02863 8.5e-37
MGECLEDA_02864 4.9e-76
MGECLEDA_02865 1.6e-10 S Mor transcription activator family
MGECLEDA_02866 2.3e-29
MGECLEDA_02867 5.9e-23 S Mor transcription activator family
MGECLEDA_02868 3.5e-16
MGECLEDA_02869 6.6e-14 S Mor transcription activator family
MGECLEDA_02871 3e-43 L Transposase and inactivated derivatives, IS30 family
MGECLEDA_02872 2.1e-198 S Membrane
MGECLEDA_02873 5.2e-259 S Domain of unknown function DUF87
MGECLEDA_02874 1.9e-56 dptG
MGECLEDA_02875 6.8e-72 dptF L COG0433 Predicted ATPase
MGECLEDA_02876 9.8e-39 L Transposase and inactivated derivatives
MGECLEDA_02877 4.3e-155 L Integrase core domain
MGECLEDA_02878 1.6e-09
MGECLEDA_02879 5.9e-53 ydeA S intracellular protease amidase
MGECLEDA_02880 3.4e-37 K Bacterial regulatory proteins, tetR family
MGECLEDA_02881 6.3e-109 XK27_06930 S ABC-2 family transporter protein
MGECLEDA_02882 1.2e-10 S Domain of unknown function (DUF4260)
MGECLEDA_02883 1.3e-23 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MGECLEDA_02884 1.9e-29 yobT S PFAM Metallo-beta-lactamase superfamily
MGECLEDA_02885 4.4e-39
MGECLEDA_02886 3.9e-120 Q Methyltransferase domain
MGECLEDA_02887 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MGECLEDA_02888 4.9e-172 K AI-2E family transporter
MGECLEDA_02889 2.9e-210 xylR GK ROK family
MGECLEDA_02890 2.4e-83
MGECLEDA_02891 2.3e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MGECLEDA_02892 3.6e-163
MGECLEDA_02893 1e-201 KLT Protein tyrosine kinase
MGECLEDA_02894 6.8e-25 S Protein of unknown function (DUF4064)
MGECLEDA_02895 6e-97 S Domain of unknown function (DUF4352)
MGECLEDA_02896 3.9e-75 S Psort location Cytoplasmic, score
MGECLEDA_02898 4.1e-54
MGECLEDA_02899 1.8e-109 S membrane transporter protein
MGECLEDA_02900 2.3e-54 azlD S branched-chain amino acid
MGECLEDA_02901 5.1e-131 azlC E branched-chain amino acid
MGECLEDA_02902 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MGECLEDA_02903 4.9e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MGECLEDA_02904 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
MGECLEDA_02905 3.2e-124 K response regulator
MGECLEDA_02906 2e-121 yoaK S Protein of unknown function (DUF1275)
MGECLEDA_02907 2.2e-160 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MGECLEDA_02908 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MGECLEDA_02909 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
MGECLEDA_02910 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MGECLEDA_02911 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
MGECLEDA_02912 1.8e-156 spo0J K Belongs to the ParB family
MGECLEDA_02913 1.8e-136 soj D Sporulation initiation inhibitor
MGECLEDA_02914 1.4e-148 noc K Belongs to the ParB family
MGECLEDA_02915 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MGECLEDA_02916 4.1e-226 nupG F Nucleoside
MGECLEDA_02917 2.2e-161 S Bacterial membrane protein, YfhO
MGECLEDA_02918 1.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
MGECLEDA_02919 6.1e-168 K LysR substrate binding domain
MGECLEDA_02920 4e-234 EK Aminotransferase, class I
MGECLEDA_02921 1.8e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MGECLEDA_02922 8.1e-123 tcyB E ABC transporter
MGECLEDA_02923 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MGECLEDA_02924 2.2e-119 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MGECLEDA_02925 3.8e-78 KT response to antibiotic
MGECLEDA_02926 1.5e-52 K Transcriptional regulator
MGECLEDA_02927 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
MGECLEDA_02928 5.5e-127 S Putative adhesin
MGECLEDA_02929 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
MGECLEDA_02930 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MGECLEDA_02931 1.4e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
MGECLEDA_02932 2.6e-205 S DUF218 domain
MGECLEDA_02933 2e-127 ybbM S Uncharacterised protein family (UPF0014)
MGECLEDA_02934 1.4e-116 ybbL S ABC transporter, ATP-binding protein
MGECLEDA_02935 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MGECLEDA_02936 9.4e-77
MGECLEDA_02937 6.5e-151 qorB 1.6.5.2 GM NmrA-like family
MGECLEDA_02938 1.1e-147 cof S haloacid dehalogenase-like hydrolase
MGECLEDA_02939 1.1e-92 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MGECLEDA_02940 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
MGECLEDA_02941 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
MGECLEDA_02942 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
MGECLEDA_02943 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MGECLEDA_02944 2.2e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MGECLEDA_02945 2e-77 merR K MerR family regulatory protein
MGECLEDA_02946 2.6e-155 1.6.5.2 GM NmrA-like family
MGECLEDA_02947 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
MGECLEDA_02948 1.1e-126 magIII L Base excision DNA repair protein, HhH-GPD family
MGECLEDA_02949 1.4e-08
MGECLEDA_02950 5.8e-100 S NADPH-dependent FMN reductase
MGECLEDA_02951 7.9e-238 S module of peptide synthetase
MGECLEDA_02952 4.2e-104
MGECLEDA_02953 9.8e-88 perR P Belongs to the Fur family
MGECLEDA_02954 7.1e-59 S Enterocin A Immunity
MGECLEDA_02955 5.4e-36 S Phospholipase_D-nuclease N-terminal
MGECLEDA_02956 1.8e-169 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
MGECLEDA_02957 2.5e-103 J Acetyltransferase (GNAT) domain
MGECLEDA_02958 5.1e-64 lrgA S LrgA family
MGECLEDA_02959 7.3e-127 lrgB M LrgB-like family
MGECLEDA_02960 2.5e-145 DegV S EDD domain protein, DegV family
MGECLEDA_02961 4.1e-25
MGECLEDA_02962 3.5e-118 yugP S Putative neutral zinc metallopeptidase
MGECLEDA_02963 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
MGECLEDA_02964 6.2e-165 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
MGECLEDA_02965 1.7e-184 D Alpha beta
MGECLEDA_02966 4.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MGECLEDA_02967 8.1e-257 gor 1.8.1.7 C Glutathione reductase
MGECLEDA_02968 3.4e-55 S Enterocin A Immunity
MGECLEDA_02969 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MGECLEDA_02970 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MGECLEDA_02971 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MGECLEDA_02972 4.4e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
MGECLEDA_02973 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MGECLEDA_02975 6.2e-82
MGECLEDA_02976 1.5e-256 yhdG E C-terminus of AA_permease
MGECLEDA_02978 0.0 kup P Transport of potassium into the cell
MGECLEDA_02979 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MGECLEDA_02980 3.1e-179 K AI-2E family transporter
MGECLEDA_02981 4e-217 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
MGECLEDA_02982 9.9e-59 qacC P Small Multidrug Resistance protein
MGECLEDA_02983 1.1e-44 qacH U Small Multidrug Resistance protein
MGECLEDA_02984 3e-116 hly S protein, hemolysin III
MGECLEDA_02985 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
MGECLEDA_02986 2.7e-160 czcD P cation diffusion facilitator family transporter
MGECLEDA_02987 2.7e-103 K Helix-turn-helix XRE-family like proteins
MGECLEDA_02989 2.1e-21
MGECLEDA_02991 6.5e-96 tag 3.2.2.20 L glycosylase
MGECLEDA_02992 1.2e-213 folP 2.5.1.15 H dihydropteroate synthase
MGECLEDA_02993 1.7e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
MGECLEDA_02994 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MGECLEDA_02995 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
MGECLEDA_02996 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MGECLEDA_02997 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MGECLEDA_02998 4.7e-83 cvpA S Colicin V production protein
MGECLEDA_02999 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
MGECLEDA_03000 1.3e-249 EGP Major facilitator Superfamily
MGECLEDA_03002 1.2e-39
MGECLEDA_03003 1.4e-95 V VanZ like family
MGECLEDA_03004 3.2e-194 blaA6 V Beta-lactamase
MGECLEDA_03005 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MGECLEDA_03006 1.9e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MGECLEDA_03007 5.1e-53 yitW S Pfam:DUF59
MGECLEDA_03008 5.9e-174 S Aldo keto reductase
MGECLEDA_03009 3.3e-97 FG HIT domain
MGECLEDA_03010 6.9e-37 S Bacteriocin-protection, YdeI or OmpD-Associated
MGECLEDA_03011 1.4e-77
MGECLEDA_03012 6.2e-122 E GDSL-like Lipase/Acylhydrolase family
MGECLEDA_03013 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
MGECLEDA_03014 0.0 cadA P P-type ATPase
MGECLEDA_03016 4.8e-125 yyaQ S YjbR
MGECLEDA_03017 4e-57 S Uncharacterized protein conserved in bacteria (DUF2325)
MGECLEDA_03018 5.2e-150 S Uncharacterized protein conserved in bacteria (DUF2325)
MGECLEDA_03019 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MGECLEDA_03020 1.3e-199 frlB M SIS domain
MGECLEDA_03021 8e-27 3.2.2.10 S Belongs to the LOG family
MGECLEDA_03022 1.5e-253 nhaC C Na H antiporter NhaC
MGECLEDA_03023 1.8e-251 cycA E Amino acid permease
MGECLEDA_03024 3.6e-168 S Alpha/beta hydrolase of unknown function (DUF915)
MGECLEDA_03025 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)