ORF_ID e_value Gene_name EC_number CAZy COGs Description
AAAAPHLE_00001 2.7e-79 T Universal stress protein family
AAAAPHLE_00002 2.2e-99 padR K Virulence activator alpha C-term
AAAAPHLE_00003 1.7e-104 padC Q Phenolic acid decarboxylase
AAAAPHLE_00004 8.5e-145 tesE Q hydratase
AAAAPHLE_00005 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
AAAAPHLE_00006 1.2e-157 degV S DegV family
AAAAPHLE_00007 2.9e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
AAAAPHLE_00008 1.5e-255 pepC 3.4.22.40 E aminopeptidase
AAAAPHLE_00010 4.7e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AAAAPHLE_00011 3.6e-301
AAAAPHLE_00013 1.2e-159 S Bacterial protein of unknown function (DUF916)
AAAAPHLE_00014 6.9e-93 S Cell surface protein
AAAAPHLE_00015 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AAAAPHLE_00016 1.3e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AAAAPHLE_00017 2.5e-130 jag S R3H domain protein
AAAAPHLE_00018 9.3e-239 Q Imidazolonepropionase and related amidohydrolases
AAAAPHLE_00019 2.7e-310 E ABC transporter, substratebinding protein
AAAAPHLE_00020 1.2e-104 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AAAAPHLE_00021 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AAAAPHLE_00022 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AAAAPHLE_00023 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AAAAPHLE_00024 5e-37 yaaA S S4 domain protein YaaA
AAAAPHLE_00025 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AAAAPHLE_00026 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAAAPHLE_00027 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAAAPHLE_00028 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
AAAAPHLE_00029 6.4e-60 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AAAAPHLE_00030 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AAAAPHLE_00031 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AAAAPHLE_00032 1.4e-67 rplI J Binds to the 23S rRNA
AAAAPHLE_00033 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AAAAPHLE_00034 8.8e-226 yttB EGP Major facilitator Superfamily
AAAAPHLE_00035 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AAAAPHLE_00036 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AAAAPHLE_00037 1.9e-276 E ABC transporter, substratebinding protein
AAAAPHLE_00038 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AAAAPHLE_00039 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AAAAPHLE_00040 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
AAAAPHLE_00041 2.8e-279 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
AAAAPHLE_00042 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AAAAPHLE_00043 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
AAAAPHLE_00045 4.5e-143 S haloacid dehalogenase-like hydrolase
AAAAPHLE_00046 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
AAAAPHLE_00047 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
AAAAPHLE_00048 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
AAAAPHLE_00049 1.6e-31 cspA K Cold shock protein domain
AAAAPHLE_00050 1.7e-37
AAAAPHLE_00051 2e-227 sip L Belongs to the 'phage' integrase family
AAAAPHLE_00052 5.5e-124 K sequence-specific DNA binding
AAAAPHLE_00054 1.7e-08
AAAAPHLE_00056 8.7e-34
AAAAPHLE_00058 5.2e-142 L DNA replication protein
AAAAPHLE_00059 5e-56 S Phage plasmid primase P4 family
AAAAPHLE_00060 3.9e-17
AAAAPHLE_00061 2e-23
AAAAPHLE_00062 9.9e-50 S head-tail joining protein
AAAAPHLE_00063 7.5e-70 L Phage-associated protein
AAAAPHLE_00064 1e-81 terS L overlaps another CDS with the same product name
AAAAPHLE_00065 0.0 terL S overlaps another CDS with the same product name
AAAAPHLE_00067 1.7e-204 S Phage portal protein
AAAAPHLE_00068 8.2e-277 S Caudovirus prohead serine protease
AAAAPHLE_00069 1.5e-40 S Phage gp6-like head-tail connector protein
AAAAPHLE_00070 1.9e-57
AAAAPHLE_00071 6e-31 cspA K Cold shock protein
AAAAPHLE_00072 3.1e-39
AAAAPHLE_00074 6.2e-131 K response regulator
AAAAPHLE_00075 0.0 vicK 2.7.13.3 T Histidine kinase
AAAAPHLE_00076 1.2e-244 yycH S YycH protein
AAAAPHLE_00077 2.2e-151 yycI S YycH protein
AAAAPHLE_00078 8.9e-158 vicX 3.1.26.11 S domain protein
AAAAPHLE_00079 6.8e-173 htrA 3.4.21.107 O serine protease
AAAAPHLE_00080 3.6e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AAAAPHLE_00081 2.4e-85 S membrane transporter protein
AAAAPHLE_00082 4.3e-91 ung2 3.2.2.27 L Uracil-DNA glycosylase
AAAAPHLE_00083 1.1e-121 pnb C nitroreductase
AAAAPHLE_00084 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
AAAAPHLE_00085 2.3e-116 S Elongation factor G-binding protein, N-terminal
AAAAPHLE_00086 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
AAAAPHLE_00087 1.6e-258 P Sodium:sulfate symporter transmembrane region
AAAAPHLE_00088 1.2e-155 K LysR family
AAAAPHLE_00089 3.9e-72 C FMN binding
AAAAPHLE_00090 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AAAAPHLE_00091 2.3e-164 ptlF S KR domain
AAAAPHLE_00092 7.1e-158 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
AAAAPHLE_00093 1.3e-122 drgA C Nitroreductase family
AAAAPHLE_00094 1.1e-289 QT PucR C-terminal helix-turn-helix domain
AAAAPHLE_00095 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
AAAAPHLE_00096 5.1e-195 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AAAAPHLE_00097 9.6e-250 yjjP S Putative threonine/serine exporter
AAAAPHLE_00098 1.7e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
AAAAPHLE_00099 2.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
AAAAPHLE_00100 2.9e-81 6.3.3.2 S ASCH
AAAAPHLE_00101 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
AAAAPHLE_00102 5.5e-172 yobV1 K WYL domain
AAAAPHLE_00103 1.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AAAAPHLE_00104 0.0 tetP J elongation factor G
AAAAPHLE_00105 1.2e-126 S Protein of unknown function
AAAAPHLE_00106 1.4e-151 EG EamA-like transporter family
AAAAPHLE_00107 6.7e-50 MA20_25245 K FR47-like protein
AAAAPHLE_00108 2e-126 hchA S DJ-1/PfpI family
AAAAPHLE_00109 5.2e-184 1.1.1.1 C nadph quinone reductase
AAAAPHLE_00110 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
AAAAPHLE_00111 3.9e-235 mepA V MATE efflux family protein
AAAAPHLE_00112 8.1e-81 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
AAAAPHLE_00113 5.5e-64 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
AAAAPHLE_00114 1.5e-138 S Belongs to the UPF0246 family
AAAAPHLE_00115 6e-76
AAAAPHLE_00116 1.6e-277 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
AAAAPHLE_00117 2.4e-141
AAAAPHLE_00119 4.6e-143 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
AAAAPHLE_00120 4.8e-40
AAAAPHLE_00121 3.9e-128 cbiO P ABC transporter
AAAAPHLE_00122 6.9e-150 P Cobalt transport protein
AAAAPHLE_00123 4.8e-182 nikMN P PDGLE domain
AAAAPHLE_00124 4.2e-121 K Crp-like helix-turn-helix domain
AAAAPHLE_00125 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
AAAAPHLE_00126 5.3e-125 larB S AIR carboxylase
AAAAPHLE_00127 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AAAAPHLE_00128 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
AAAAPHLE_00129 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AAAAPHLE_00130 8.3e-151 larE S NAD synthase
AAAAPHLE_00131 2.1e-177 1.6.5.5 C Zinc-binding dehydrogenase
AAAAPHLE_00132 5.8e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AAAAPHLE_00133 1.6e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AAAAPHLE_00134 9.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
AAAAPHLE_00135 7.6e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
AAAAPHLE_00136 4.3e-135 S peptidase C26
AAAAPHLE_00137 2e-302 L HIRAN domain
AAAAPHLE_00138 9.9e-85 F NUDIX domain
AAAAPHLE_00139 2.6e-250 yifK E Amino acid permease
AAAAPHLE_00140 1.7e-120
AAAAPHLE_00141 5.6e-149 ydjP I Alpha/beta hydrolase family
AAAAPHLE_00142 0.0 pacL1 P P-type ATPase
AAAAPHLE_00143 1.6e-28 KT PspC domain
AAAAPHLE_00144 1.5e-109 S NADPH-dependent FMN reductase
AAAAPHLE_00145 1.2e-74 papX3 K Transcriptional regulator
AAAAPHLE_00146 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
AAAAPHLE_00147 5.8e-82 S Protein of unknown function (DUF3021)
AAAAPHLE_00148 4.7e-227 mdtG EGP Major facilitator Superfamily
AAAAPHLE_00149 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
AAAAPHLE_00150 2.3e-215 yeaN P Transporter, major facilitator family protein
AAAAPHLE_00152 3.4e-160 S reductase
AAAAPHLE_00153 1.2e-165 1.1.1.65 C Aldo keto reductase
AAAAPHLE_00154 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
AAAAPHLE_00155 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
AAAAPHLE_00156 3.7e-47
AAAAPHLE_00157 3.8e-255
AAAAPHLE_00158 6.4e-207 C Oxidoreductase
AAAAPHLE_00159 7.1e-150 cbiQ P cobalt transport
AAAAPHLE_00160 0.0 ykoD P ABC transporter, ATP-binding protein
AAAAPHLE_00161 2.5e-98 S UPF0397 protein
AAAAPHLE_00162 1.6e-129 K UbiC transcription regulator-associated domain protein
AAAAPHLE_00163 8.3e-54 K Transcriptional regulator PadR-like family
AAAAPHLE_00164 3.9e-142
AAAAPHLE_00165 4.7e-151
AAAAPHLE_00166 9.1e-89
AAAAPHLE_00167 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
AAAAPHLE_00168 6.7e-170 yjjC V ABC transporter
AAAAPHLE_00169 4.6e-299 M Exporter of polyketide antibiotics
AAAAPHLE_00170 1.2e-115 K Transcriptional regulator
AAAAPHLE_00171 1.2e-275 C Electron transfer flavoprotein FAD-binding domain
AAAAPHLE_00172 1.1e-73 folT 2.7.13.3 T ECF transporter, substrate-specific component
AAAAPHLE_00174 1.1e-92 K Bacterial regulatory proteins, tetR family
AAAAPHLE_00175 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
AAAAPHLE_00176 1.5e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
AAAAPHLE_00177 1.9e-101 dhaL 2.7.1.121 S Dak2
AAAAPHLE_00178 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
AAAAPHLE_00179 8.6e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AAAAPHLE_00180 1e-190 malR K Transcriptional regulator, LacI family
AAAAPHLE_00181 2e-180 yvdE K helix_turn _helix lactose operon repressor
AAAAPHLE_00182 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
AAAAPHLE_00183 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
AAAAPHLE_00184 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
AAAAPHLE_00185 1.4e-161 malD P ABC transporter permease
AAAAPHLE_00186 5.3e-150 malA S maltodextrose utilization protein MalA
AAAAPHLE_00187 1.5e-258 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
AAAAPHLE_00188 4e-209 msmK P Belongs to the ABC transporter superfamily
AAAAPHLE_00189 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
AAAAPHLE_00190 0.0 3.2.1.96 G Glycosyl hydrolase family 85
AAAAPHLE_00191 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
AAAAPHLE_00192 3.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
AAAAPHLE_00193 0.0 rafA 3.2.1.22 G alpha-galactosidase
AAAAPHLE_00194 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
AAAAPHLE_00195 1.5e-304 scrB 3.2.1.26 GH32 G invertase
AAAAPHLE_00196 9.1e-173 scrR K Transcriptional regulator, LacI family
AAAAPHLE_00197 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
AAAAPHLE_00198 1.3e-165 3.5.1.10 C nadph quinone reductase
AAAAPHLE_00199 1.1e-217 nhaC C Na H antiporter NhaC
AAAAPHLE_00200 6.7e-200 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
AAAAPHLE_00201 1.8e-101 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
AAAAPHLE_00202 7.2e-164 mleR K LysR substrate binding domain
AAAAPHLE_00203 0.0 3.6.4.13 M domain protein
AAAAPHLE_00205 6.6e-156 hipB K Helix-turn-helix
AAAAPHLE_00206 1.3e-151 oppA E ABC transporter, substratebinding protein
AAAAPHLE_00207 1.7e-128 oppA E ABC transporter, substratebinding protein
AAAAPHLE_00208 1.8e-309 oppA E ABC transporter, substratebinding protein
AAAAPHLE_00209 1.3e-78 yiaC K Acetyltransferase (GNAT) domain
AAAAPHLE_00210 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAAAPHLE_00211 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AAAAPHLE_00212 8.7e-113 pgm1 G phosphoglycerate mutase
AAAAPHLE_00213 2.2e-179 yghZ C Aldo keto reductase family protein
AAAAPHLE_00214 4.9e-34
AAAAPHLE_00215 1.3e-60 S Domain of unknown function (DU1801)
AAAAPHLE_00216 4e-164 FbpA K Domain of unknown function (DUF814)
AAAAPHLE_00217 1.7e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AAAAPHLE_00219 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AAAAPHLE_00220 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AAAAPHLE_00221 8e-261 S ATPases associated with a variety of cellular activities
AAAAPHLE_00222 1.8e-116 P cobalt transport
AAAAPHLE_00223 5.3e-259 P ABC transporter
AAAAPHLE_00224 3.1e-101 S ABC transporter permease
AAAAPHLE_00225 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
AAAAPHLE_00226 4.1e-158 dkgB S reductase
AAAAPHLE_00227 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AAAAPHLE_00228 2.4e-66
AAAAPHLE_00229 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AAAAPHLE_00230 1e-173 P Major Facilitator Superfamily
AAAAPHLE_00231 6.6e-223 1.3.5.4 C FAD dependent oxidoreductase
AAAAPHLE_00232 3.1e-98 K Helix-turn-helix domain
AAAAPHLE_00233 2.6e-277 pipD E Dipeptidase
AAAAPHLE_00234 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
AAAAPHLE_00235 0.0 mtlR K Mga helix-turn-helix domain
AAAAPHLE_00236 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_00237 9.5e-222 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
AAAAPHLE_00238 2.9e-75
AAAAPHLE_00239 6.2e-57 trxA1 O Belongs to the thioredoxin family
AAAAPHLE_00240 1.2e-49
AAAAPHLE_00241 2.5e-95
AAAAPHLE_00242 2.9e-61
AAAAPHLE_00243 3.9e-81 ndk 2.7.4.6 F Belongs to the NDK family
AAAAPHLE_00244 9.9e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
AAAAPHLE_00245 3.5e-97 yieF S NADPH-dependent FMN reductase
AAAAPHLE_00246 7.2e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
AAAAPHLE_00247 4.9e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AAAAPHLE_00248 2.2e-165 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AAAAPHLE_00249 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
AAAAPHLE_00250 9.5e-141 pnuC H nicotinamide mononucleotide transporter
AAAAPHLE_00251 7.3e-43 S Protein of unknown function (DUF2089)
AAAAPHLE_00252 3.7e-42
AAAAPHLE_00253 3.5e-129 treR K UTRA
AAAAPHLE_00254 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
AAAAPHLE_00255 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
AAAAPHLE_00256 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
AAAAPHLE_00257 1.4e-144
AAAAPHLE_00258 6.3e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
AAAAPHLE_00259 1.6e-70
AAAAPHLE_00260 1.8e-72 K Transcriptional regulator
AAAAPHLE_00261 4.3e-121 K Bacterial regulatory proteins, tetR family
AAAAPHLE_00262 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
AAAAPHLE_00263 5.5e-118
AAAAPHLE_00264 5.2e-42
AAAAPHLE_00265 1e-40
AAAAPHLE_00266 9.7e-253 ydiC1 EGP Major facilitator Superfamily
AAAAPHLE_00267 9.5e-65 K helix_turn_helix, mercury resistance
AAAAPHLE_00268 2.3e-251 T PhoQ Sensor
AAAAPHLE_00269 4.4e-129 K Transcriptional regulatory protein, C terminal
AAAAPHLE_00270 1.8e-49
AAAAPHLE_00271 1.3e-128 yidA K Helix-turn-helix domain, rpiR family
AAAAPHLE_00272 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_00273 9.9e-57
AAAAPHLE_00274 2.1e-41
AAAAPHLE_00275 5.4e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AAAAPHLE_00276 7.6e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
AAAAPHLE_00277 1.3e-47
AAAAPHLE_00278 7.9e-123 2.7.6.5 S RelA SpoT domain protein
AAAAPHLE_00279 3.1e-104 K transcriptional regulator
AAAAPHLE_00280 0.0 ydgH S MMPL family
AAAAPHLE_00281 1e-107 tag 3.2.2.20 L glycosylase
AAAAPHLE_00282 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
AAAAPHLE_00283 1.7e-183 yclI V MacB-like periplasmic core domain
AAAAPHLE_00284 3.5e-120 yclH V ABC transporter
AAAAPHLE_00285 2.5e-114 V CAAX protease self-immunity
AAAAPHLE_00286 1e-120 S CAAX protease self-immunity
AAAAPHLE_00287 8.5e-52 M Lysin motif
AAAAPHLE_00288 1.2e-37 lytE M LysM domain protein
AAAAPHLE_00289 6.3e-66 gcvH E Glycine cleavage H-protein
AAAAPHLE_00290 1.1e-177 sepS16B
AAAAPHLE_00291 1.3e-131
AAAAPHLE_00292 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
AAAAPHLE_00293 2.2e-55
AAAAPHLE_00294 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AAAAPHLE_00295 6.5e-78 elaA S GNAT family
AAAAPHLE_00296 1.7e-75 K Transcriptional regulator
AAAAPHLE_00297 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
AAAAPHLE_00298 4.3e-40
AAAAPHLE_00299 4e-206 potD P ABC transporter
AAAAPHLE_00300 3.4e-141 potC P ABC transporter permease
AAAAPHLE_00301 2.3e-148 potB P ABC transporter permease
AAAAPHLE_00302 1.2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AAAAPHLE_00303 5e-96 puuR K Cupin domain
AAAAPHLE_00304 3.2e-83 6.3.3.2 S ASCH
AAAAPHLE_00305 1e-84 K GNAT family
AAAAPHLE_00306 1.8e-90 K acetyltransferase
AAAAPHLE_00307 8.1e-22
AAAAPHLE_00308 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
AAAAPHLE_00309 2e-163 ytrB V ABC transporter
AAAAPHLE_00310 4.9e-190
AAAAPHLE_00311 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
AAAAPHLE_00312 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
AAAAPHLE_00314 3.4e-239 xylP1 G MFS/sugar transport protein
AAAAPHLE_00315 3e-122 qmcA O prohibitin homologues
AAAAPHLE_00316 1.5e-29
AAAAPHLE_00317 1.7e-281 pipD E Dipeptidase
AAAAPHLE_00318 3e-40
AAAAPHLE_00319 6.8e-96 bioY S BioY family
AAAAPHLE_00320 1.9e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AAAAPHLE_00321 6.5e-111 metQ P NLPA lipoprotein
AAAAPHLE_00322 6.7e-126 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AAAAPHLE_00323 1.1e-86 metI U Binding-protein-dependent transport system inner membrane component
AAAAPHLE_00324 7.7e-148 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AAAAPHLE_00325 3.3e-222 mtnE 2.6.1.83 E Aminotransferase
AAAAPHLE_00326 1.1e-217
AAAAPHLE_00327 3.5e-154 tagG U Transport permease protein
AAAAPHLE_00328 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AAAAPHLE_00329 8.4e-44
AAAAPHLE_00330 3.9e-93 K Transcriptional regulator PadR-like family
AAAAPHLE_00331 3.5e-258 P Major Facilitator Superfamily
AAAAPHLE_00332 4.7e-241 amtB P ammonium transporter
AAAAPHLE_00333 2e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
AAAAPHLE_00334 3.7e-44
AAAAPHLE_00335 6.3e-102 zmp1 O Zinc-dependent metalloprotease
AAAAPHLE_00336 1.8e-119 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
AAAAPHLE_00337 1.5e-310 mco Q Multicopper oxidase
AAAAPHLE_00338 1.1e-54 ypaA S Protein of unknown function (DUF1304)
AAAAPHLE_00339 3.3e-94 yxkA S Phosphatidylethanolamine-binding protein
AAAAPHLE_00340 1.6e-232 flhF N Uncharacterized conserved protein (DUF2075)
AAAAPHLE_00341 1.6e-82 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
AAAAPHLE_00342 9.3e-80
AAAAPHLE_00343 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AAAAPHLE_00344 4.5e-174 rihC 3.2.2.1 F Nucleoside
AAAAPHLE_00345 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
AAAAPHLE_00346 0.0
AAAAPHLE_00347 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
AAAAPHLE_00348 1.8e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AAAAPHLE_00349 3e-47 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
AAAAPHLE_00350 3.3e-118 proV E ABC transporter, ATP-binding protein
AAAAPHLE_00351 2.2e-254 gshR 1.8.1.7 C Pyridine nucleotide-disulphide oxidoreductase
AAAAPHLE_00352 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AAAAPHLE_00353 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
AAAAPHLE_00354 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AAAAPHLE_00355 0.0 M domain protein
AAAAPHLE_00356 9.8e-32 M self proteolysis
AAAAPHLE_00357 2.1e-54 ankB S ankyrin repeats
AAAAPHLE_00358 5.6e-37
AAAAPHLE_00359 2.4e-38
AAAAPHLE_00360 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
AAAAPHLE_00361 1.1e-196 uhpT EGP Major facilitator Superfamily
AAAAPHLE_00362 1.2e-146 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
AAAAPHLE_00363 1.6e-165 K Transcriptional regulator
AAAAPHLE_00364 1.4e-150 S hydrolase
AAAAPHLE_00365 2e-255 brnQ U Component of the transport system for branched-chain amino acids
AAAAPHLE_00366 3.6e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AAAAPHLE_00367 2.3e-30
AAAAPHLE_00368 5e-114
AAAAPHLE_00369 8.8e-57 2.7.13.3 T GHKL domain
AAAAPHLE_00370 2.5e-130 plnD K LytTr DNA-binding domain
AAAAPHLE_00371 9.1e-128 S CAAX protease self-immunity
AAAAPHLE_00372 2.4e-22 plnF
AAAAPHLE_00373 6.7e-23
AAAAPHLE_00374 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AAAAPHLE_00375 1.7e-241 mesE M Transport protein ComB
AAAAPHLE_00376 5.9e-110 S CAAX protease self-immunity
AAAAPHLE_00377 1.7e-15 ypbD S CAAX protease self-immunity
AAAAPHLE_00378 5.8e-68 ypbD S CAAX protease self-immunity
AAAAPHLE_00379 8.4e-100 V CAAX protease self-immunity
AAAAPHLE_00380 3.6e-112 S CAAX protease self-immunity
AAAAPHLE_00381 6.9e-36 S RelE-like toxin of type II toxin-antitoxin system HigB
AAAAPHLE_00382 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
AAAAPHLE_00383 0.0 helD 3.6.4.12 L DNA helicase
AAAAPHLE_00384 3.2e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
AAAAPHLE_00385 1.7e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
AAAAPHLE_00386 9e-130 K UbiC transcription regulator-associated domain protein
AAAAPHLE_00387 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_00388 1.1e-23
AAAAPHLE_00389 2.6e-76 S Domain of unknown function (DUF3284)
AAAAPHLE_00390 2.4e-34 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_00391 8.8e-201 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_00392 7.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_00393 2e-163 GK ROK family
AAAAPHLE_00394 4.1e-133 K Helix-turn-helix domain, rpiR family
AAAAPHLE_00395 1.4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AAAAPHLE_00396 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
AAAAPHLE_00397 6.8e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
AAAAPHLE_00398 1.6e-177
AAAAPHLE_00399 3.9e-133 cobB K SIR2 family
AAAAPHLE_00400 2e-160 yunF F Protein of unknown function DUF72
AAAAPHLE_00401 2.6e-70 mutT 3.6.1.55 F DNA mismatch repair protein MutT
AAAAPHLE_00402 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAAAPHLE_00403 1.3e-213 bcr1 EGP Major facilitator Superfamily
AAAAPHLE_00404 5.1e-106 mutR K sequence-specific DNA binding
AAAAPHLE_00406 1.5e-146 tatD L hydrolase, TatD family
AAAAPHLE_00407 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AAAAPHLE_00408 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AAAAPHLE_00409 3.2e-37 veg S Biofilm formation stimulator VEG
AAAAPHLE_00410 2.2e-162 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AAAAPHLE_00411 6.7e-181 S Prolyl oligopeptidase family
AAAAPHLE_00412 9.8e-129 fhuC 3.6.3.35 P ABC transporter
AAAAPHLE_00413 9.2e-131 znuB U ABC 3 transport family
AAAAPHLE_00414 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
AAAAPHLE_00415 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AAAAPHLE_00416 7.4e-152 bla1 3.5.2.6 V Beta-lactamase enzyme family
AAAAPHLE_00417 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AAAAPHLE_00418 7.2e-181 S DUF218 domain
AAAAPHLE_00419 4.1e-125
AAAAPHLE_00420 1.7e-148 yxeH S hydrolase
AAAAPHLE_00421 9e-264 ywfO S HD domain protein
AAAAPHLE_00422 1.8e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
AAAAPHLE_00423 3.8e-78 ywiB S Domain of unknown function (DUF1934)
AAAAPHLE_00424 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AAAAPHLE_00425 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AAAAPHLE_00426 1.8e-245 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AAAAPHLE_00427 3.1e-229 tdcC E amino acid
AAAAPHLE_00428 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
AAAAPHLE_00429 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
AAAAPHLE_00430 6.4e-131 S YheO-like PAS domain
AAAAPHLE_00431 2.5e-26
AAAAPHLE_00432 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAAAPHLE_00433 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AAAAPHLE_00434 7.8e-41 rpmE2 J Ribosomal protein L31
AAAAPHLE_00435 3.2e-214 J translation release factor activity
AAAAPHLE_00436 9.2e-127 srtA 3.4.22.70 M sortase family
AAAAPHLE_00437 1.7e-91 lemA S LemA family
AAAAPHLE_00438 1e-138 htpX O Belongs to the peptidase M48B family
AAAAPHLE_00439 2e-146
AAAAPHLE_00440 5.6e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AAAAPHLE_00441 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AAAAPHLE_00442 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AAAAPHLE_00443 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AAAAPHLE_00444 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
AAAAPHLE_00445 0.0 kup P Transport of potassium into the cell
AAAAPHLE_00446 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AAAAPHLE_00447 1.8e-203 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AAAAPHLE_00448 3.6e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AAAAPHLE_00449 6.9e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AAAAPHLE_00450 1e-128 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
AAAAPHLE_00451 1.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
AAAAPHLE_00452 2.7e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AAAAPHLE_00453 4.1e-84 S QueT transporter
AAAAPHLE_00454 2.1e-114 S (CBS) domain
AAAAPHLE_00455 6.4e-265 S Putative peptidoglycan binding domain
AAAAPHLE_00456 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AAAAPHLE_00457 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AAAAPHLE_00458 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AAAAPHLE_00459 7.3e-289 yabM S Polysaccharide biosynthesis protein
AAAAPHLE_00460 2.2e-42 yabO J S4 domain protein
AAAAPHLE_00462 1.1e-63 divIC D Septum formation initiator
AAAAPHLE_00463 3.1e-74 yabR J RNA binding
AAAAPHLE_00464 6.9e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AAAAPHLE_00465 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AAAAPHLE_00466 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AAAAPHLE_00467 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AAAAPHLE_00468 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AAAAPHLE_00469 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AAAAPHLE_00472 3e-252 dtpT U amino acid peptide transporter
AAAAPHLE_00473 2e-151 yjjH S Calcineurin-like phosphoesterase
AAAAPHLE_00477 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
AAAAPHLE_00478 2.5e-53 S Cupin domain
AAAAPHLE_00479 4.9e-167 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
AAAAPHLE_00480 1.2e-192 ybiR P Citrate transporter
AAAAPHLE_00481 8.2e-151 pnuC H nicotinamide mononucleotide transporter
AAAAPHLE_00482 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AAAAPHLE_00483 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AAAAPHLE_00484 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
AAAAPHLE_00485 1.2e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
AAAAPHLE_00486 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AAAAPHLE_00487 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AAAAPHLE_00488 0.0 pacL 3.6.3.8 P P-type ATPase
AAAAPHLE_00489 1.5e-71
AAAAPHLE_00490 0.0 yhgF K Tex-like protein N-terminal domain protein
AAAAPHLE_00491 1.2e-82 ydcK S Belongs to the SprT family
AAAAPHLE_00492 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AAAAPHLE_00493 2.9e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AAAAPHLE_00495 2.6e-54 sip L Belongs to the 'phage' integrase family
AAAAPHLE_00496 8.3e-93 S T5orf172
AAAAPHLE_00500 1e-34
AAAAPHLE_00501 4.8e-17 E Pfam:DUF955
AAAAPHLE_00502 2.8e-21 yvaO K Helix-turn-helix XRE-family like proteins
AAAAPHLE_00503 1.1e-76 sidC GT2,GT4 LM DNA recombination
AAAAPHLE_00504 3e-20 S Protein of unknown function (DUF1617)
AAAAPHLE_00509 4e-77 ps461 M Glycosyl hydrolases family 25
AAAAPHLE_00510 5.6e-152 G Peptidase_C39 like family
AAAAPHLE_00511 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
AAAAPHLE_00512 3.4e-133 manY G PTS system
AAAAPHLE_00513 4.4e-169 manN G system, mannose fructose sorbose family IID component
AAAAPHLE_00514 4.7e-64 S Domain of unknown function (DUF956)
AAAAPHLE_00515 0.0 levR K Sigma-54 interaction domain
AAAAPHLE_00516 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
AAAAPHLE_00517 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
AAAAPHLE_00518 7.8e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AAAAPHLE_00519 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
AAAAPHLE_00520 1.2e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
AAAAPHLE_00521 3.7e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AAAAPHLE_00522 9.1e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
AAAAPHLE_00523 4.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AAAAPHLE_00524 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
AAAAPHLE_00525 8.3e-177 EG EamA-like transporter family
AAAAPHLE_00526 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AAAAPHLE_00530 8.5e-11 S DNA/RNA non-specific endonuclease
AAAAPHLE_00531 3.6e-09 S Pfam:Peptidase_M78
AAAAPHLE_00532 7.5e-22 S protein disulfide oxidoreductase activity
AAAAPHLE_00536 8.9e-07
AAAAPHLE_00537 1.5e-17 K Cro/C1-type HTH DNA-binding domain
AAAAPHLE_00541 2.9e-53
AAAAPHLE_00542 1.6e-75
AAAAPHLE_00543 1.9e-14 S Domain of unknown function (DUF1508)
AAAAPHLE_00544 1.1e-70
AAAAPHLE_00545 3.5e-155 recT L RecT family
AAAAPHLE_00546 2.4e-134 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
AAAAPHLE_00547 9e-151 L DnaD domain protein
AAAAPHLE_00548 1.8e-49
AAAAPHLE_00549 1.9e-84
AAAAPHLE_00550 5.4e-65 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AAAAPHLE_00551 6.2e-15
AAAAPHLE_00553 3.8e-43
AAAAPHLE_00554 1.5e-19
AAAAPHLE_00555 1.8e-14
AAAAPHLE_00558 5.5e-19 S KTSC domain
AAAAPHLE_00561 2e-14
AAAAPHLE_00563 1.5e-84 ps333 L Terminase small subunit
AAAAPHLE_00564 2.7e-76 ps334 S Terminase-like family
AAAAPHLE_00565 1.6e-142 ps334 S Terminase-like family
AAAAPHLE_00566 8.8e-268 S Phage portal protein, SPP1 Gp6-like
AAAAPHLE_00567 9.4e-295 S Phage Mu protein F like protein
AAAAPHLE_00568 2.4e-30
AAAAPHLE_00570 3.1e-15 S Domain of unknown function (DUF4355)
AAAAPHLE_00571 1.1e-48
AAAAPHLE_00572 2e-175 S Phage major capsid protein E
AAAAPHLE_00574 1.3e-51
AAAAPHLE_00575 1.5e-50
AAAAPHLE_00576 2.7e-89
AAAAPHLE_00577 1.4e-54
AAAAPHLE_00578 6.9e-78 S Phage tail tube protein, TTP
AAAAPHLE_00579 6.3e-64
AAAAPHLE_00580 0.0 D NLP P60 protein
AAAAPHLE_00581 1.1e-59
AAAAPHLE_00582 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
AAAAPHLE_00583 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AAAAPHLE_00584 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
AAAAPHLE_00585 1.1e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
AAAAPHLE_00586 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AAAAPHLE_00587 3.7e-205 yacL S domain protein
AAAAPHLE_00588 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAAAPHLE_00589 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AAAAPHLE_00590 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AAAAPHLE_00591 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAAAPHLE_00592 5.3e-98 yacP S YacP-like NYN domain
AAAAPHLE_00593 2.4e-101 sigH K Sigma-70 region 2
AAAAPHLE_00594 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AAAAPHLE_00595 3.4e-28 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AAAAPHLE_00596 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
AAAAPHLE_00597 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
AAAAPHLE_00598 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AAAAPHLE_00599 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AAAAPHLE_00600 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AAAAPHLE_00601 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AAAAPHLE_00602 4.6e-177 F DNA/RNA non-specific endonuclease
AAAAPHLE_00603 1.2e-38 L nuclease
AAAAPHLE_00604 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AAAAPHLE_00605 2.1e-40 K Helix-turn-helix domain
AAAAPHLE_00606 2.1e-108 yvdD 3.2.2.10 S Belongs to the LOG family
AAAAPHLE_00607 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAAAPHLE_00608 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAAAPHLE_00609 6.5e-37 nrdH O Glutaredoxin
AAAAPHLE_00610 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
AAAAPHLE_00611 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AAAAPHLE_00612 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AAAAPHLE_00613 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AAAAPHLE_00614 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AAAAPHLE_00615 2.2e-38 yaaL S Protein of unknown function (DUF2508)
AAAAPHLE_00616 1.4e-239 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AAAAPHLE_00617 1.1e-50 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AAAAPHLE_00618 1.1e-40 ulaB_1 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
AAAAPHLE_00619 2e-220 ulaA 2.7.1.194 S PTS system sugar-specific permease component
AAAAPHLE_00620 1.4e-20 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
AAAAPHLE_00621 2e-37 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
AAAAPHLE_00622 8.7e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AAAAPHLE_00623 2.4e-53 yaaQ S Cyclic-di-AMP receptor
AAAAPHLE_00624 4.8e-180 holB 2.7.7.7 L DNA polymerase III
AAAAPHLE_00625 1e-57 yabA L Involved in initiation control of chromosome replication
AAAAPHLE_00626 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AAAAPHLE_00627 3.6e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
AAAAPHLE_00628 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AAAAPHLE_00629 1.5e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
AAAAPHLE_00630 8.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
AAAAPHLE_00631 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
AAAAPHLE_00632 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
AAAAPHLE_00633 6.3e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AAAAPHLE_00634 5.1e-190 phnD P Phosphonate ABC transporter
AAAAPHLE_00635 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
AAAAPHLE_00636 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
AAAAPHLE_00637 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
AAAAPHLE_00638 5.8e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AAAAPHLE_00639 2.8e-306 uup S ABC transporter, ATP-binding protein
AAAAPHLE_00640 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AAAAPHLE_00641 6.1e-109 ydiL S CAAX protease self-immunity
AAAAPHLE_00642 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AAAAPHLE_00643 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AAAAPHLE_00644 0.0 ydaO E amino acid
AAAAPHLE_00645 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
AAAAPHLE_00646 4.3e-145 pstS P Phosphate
AAAAPHLE_00647 1.7e-114 yvyE 3.4.13.9 S YigZ family
AAAAPHLE_00648 5.9e-255 comFA L Helicase C-terminal domain protein
AAAAPHLE_00649 7.5e-126 comFC S Competence protein
AAAAPHLE_00650 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AAAAPHLE_00651 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AAAAPHLE_00652 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AAAAPHLE_00653 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
AAAAPHLE_00654 1.5e-132 K response regulator
AAAAPHLE_00655 3.5e-250 phoR 2.7.13.3 T Histidine kinase
AAAAPHLE_00656 1.1e-150 pstS P Phosphate
AAAAPHLE_00657 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
AAAAPHLE_00658 1.5e-155 pstA P Phosphate transport system permease protein PstA
AAAAPHLE_00659 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AAAAPHLE_00660 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AAAAPHLE_00661 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
AAAAPHLE_00662 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
AAAAPHLE_00663 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
AAAAPHLE_00664 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AAAAPHLE_00665 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AAAAPHLE_00666 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AAAAPHLE_00667 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AAAAPHLE_00668 1.9e-124 yliE T Putative diguanylate phosphodiesterase
AAAAPHLE_00669 9.7e-269 nox C NADH oxidase
AAAAPHLE_00670 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AAAAPHLE_00671 2e-109 yviA S Protein of unknown function (DUF421)
AAAAPHLE_00672 1.1e-61 S Protein of unknown function (DUF3290)
AAAAPHLE_00673 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
AAAAPHLE_00674 3.3e-132 yliE T Putative diguanylate phosphodiesterase
AAAAPHLE_00675 2.3e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AAAAPHLE_00676 2.5e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AAAAPHLE_00677 9.2e-212 norA EGP Major facilitator Superfamily
AAAAPHLE_00678 1.2e-117 yfbR S HD containing hydrolase-like enzyme
AAAAPHLE_00679 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AAAAPHLE_00680 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AAAAPHLE_00681 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AAAAPHLE_00682 7e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AAAAPHLE_00683 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
AAAAPHLE_00684 9.3e-87 S Short repeat of unknown function (DUF308)
AAAAPHLE_00685 1.6e-160 rapZ S Displays ATPase and GTPase activities
AAAAPHLE_00686 1.1e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AAAAPHLE_00687 3.7e-168 whiA K May be required for sporulation
AAAAPHLE_00688 4e-306 oppA E ABC transporter, substratebinding protein
AAAAPHLE_00689 1e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAAAPHLE_00690 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AAAAPHLE_00692 2.1e-244 rpoN K Sigma-54 factor, core binding domain
AAAAPHLE_00693 7.3e-189 cggR K Putative sugar-binding domain
AAAAPHLE_00694 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AAAAPHLE_00695 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AAAAPHLE_00696 6.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AAAAPHLE_00697 6.2e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AAAAPHLE_00698 4.8e-133
AAAAPHLE_00699 6.6e-295 clcA P chloride
AAAAPHLE_00700 1.2e-30 secG U Preprotein translocase
AAAAPHLE_00701 8.5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
AAAAPHLE_00702 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AAAAPHLE_00703 4.2e-09 3.4.21.72 M Bacterial Ig-like domain (group 3)
AAAAPHLE_00704 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
AAAAPHLE_00705 1.5e-256 glnP P ABC transporter
AAAAPHLE_00706 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AAAAPHLE_00707 6.1e-105 yxjI
AAAAPHLE_00708 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
AAAAPHLE_00709 6.3e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AAAAPHLE_00710 4.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
AAAAPHLE_00711 1.5e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
AAAAPHLE_00712 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
AAAAPHLE_00713 2.5e-100 dnaQ 2.7.7.7 L DNA polymerase III
AAAAPHLE_00714 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
AAAAPHLE_00715 2.5e-161 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
AAAAPHLE_00716 6.2e-168 murB 1.3.1.98 M Cell wall formation
AAAAPHLE_00717 0.0 yjcE P Sodium proton antiporter
AAAAPHLE_00718 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
AAAAPHLE_00719 7.1e-121 S Protein of unknown function (DUF1361)
AAAAPHLE_00720 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AAAAPHLE_00721 1.6e-129 ybbR S YbbR-like protein
AAAAPHLE_00722 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AAAAPHLE_00723 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AAAAPHLE_00724 4.5e-123 yliE T EAL domain
AAAAPHLE_00725 1.7e-145 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
AAAAPHLE_00726 3.1e-104 K Bacterial regulatory proteins, tetR family
AAAAPHLE_00727 2.7e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AAAAPHLE_00728 3.3e-52
AAAAPHLE_00729 3e-72
AAAAPHLE_00730 3e-131 1.5.1.39 C nitroreductase
AAAAPHLE_00731 4e-154 G Transmembrane secretion effector
AAAAPHLE_00732 1.7e-298 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AAAAPHLE_00733 8.6e-142
AAAAPHLE_00735 1.9e-71 spxA 1.20.4.1 P ArsC family
AAAAPHLE_00736 1.5e-33
AAAAPHLE_00737 3.2e-89 V VanZ like family
AAAAPHLE_00738 6e-242 EGP Major facilitator Superfamily
AAAAPHLE_00739 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
AAAAPHLE_00740 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AAAAPHLE_00741 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
AAAAPHLE_00742 1.5e-152 licD M LicD family
AAAAPHLE_00743 1.3e-82 K Transcriptional regulator
AAAAPHLE_00744 1.5e-19
AAAAPHLE_00745 1.2e-225 pbuG S permease
AAAAPHLE_00746 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AAAAPHLE_00747 5.3e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AAAAPHLE_00748 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AAAAPHLE_00749 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
AAAAPHLE_00750 3.5e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AAAAPHLE_00751 0.0 oatA I Acyltransferase
AAAAPHLE_00752 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AAAAPHLE_00753 5.6e-68 O OsmC-like protein
AAAAPHLE_00754 5.8e-46
AAAAPHLE_00755 1.1e-251 yfnA E Amino Acid
AAAAPHLE_00756 2.5e-88
AAAAPHLE_00757 1.9e-147 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
AAAAPHLE_00758 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
AAAAPHLE_00759 1.8e-19
AAAAPHLE_00760 6.3e-105 gmk2 2.7.4.8 F Guanylate kinase
AAAAPHLE_00761 1.3e-81 zur P Belongs to the Fur family
AAAAPHLE_00762 7.1e-12 3.2.1.14 GH18
AAAAPHLE_00763 4.9e-148
AAAAPHLE_00764 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
AAAAPHLE_00765 5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
AAAAPHLE_00766 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAAAPHLE_00767 8e-41
AAAAPHLE_00769 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AAAAPHLE_00770 7.8e-149 glnH ET ABC transporter substrate-binding protein
AAAAPHLE_00771 4.6e-109 gluC P ABC transporter permease
AAAAPHLE_00772 4e-108 glnP P ABC transporter permease
AAAAPHLE_00773 2.3e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AAAAPHLE_00774 3.2e-36 K CAT RNA binding domain
AAAAPHLE_00775 7.9e-258 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
AAAAPHLE_00776 1.4e-141 G YdjC-like protein
AAAAPHLE_00777 8.3e-246 steT E amino acid
AAAAPHLE_00778 5.7e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
AAAAPHLE_00779 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
AAAAPHLE_00780 2.8e-70 K MarR family
AAAAPHLE_00781 3.7e-210 EGP Major facilitator Superfamily
AAAAPHLE_00782 3.8e-85 S membrane transporter protein
AAAAPHLE_00783 1.5e-95 K Bacterial regulatory proteins, tetR family
AAAAPHLE_00784 1.9e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AAAAPHLE_00785 2.9e-78 3.6.1.55 F NUDIX domain
AAAAPHLE_00786 1.3e-48 sugE U Multidrug resistance protein
AAAAPHLE_00787 1.2e-26
AAAAPHLE_00788 5.5e-129 pgm3 G Phosphoglycerate mutase family
AAAAPHLE_00789 4.7e-125 pgm3 G Phosphoglycerate mutase family
AAAAPHLE_00790 0.0 yjbQ P TrkA C-terminal domain protein
AAAAPHLE_00791 1.6e-177 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
AAAAPHLE_00792 9.2e-158 bglG3 K CAT RNA binding domain
AAAAPHLE_00793 0.0 2.7.1.193, 2.7.1.211 G phosphotransferase system
AAAAPHLE_00794 5.1e-300 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_00795 1.4e-110 dedA S SNARE associated Golgi protein
AAAAPHLE_00796 0.0 helD 3.6.4.12 L DNA helicase
AAAAPHLE_00797 5e-165 fabK 1.3.1.9 S Nitronate monooxygenase
AAAAPHLE_00798 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
AAAAPHLE_00799 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AAAAPHLE_00800 6.2e-50
AAAAPHLE_00801 4.9e-63 K Helix-turn-helix XRE-family like proteins
AAAAPHLE_00802 0.0 L AAA domain
AAAAPHLE_00803 1.1e-116 XK27_07075 V CAAX protease self-immunity
AAAAPHLE_00804 3.8e-57 hxlR K HxlR-like helix-turn-helix
AAAAPHLE_00805 3.2e-234 EGP Major facilitator Superfamily
AAAAPHLE_00806 3.1e-153 S Cysteine-rich secretory protein family
AAAAPHLE_00807 2.2e-37 S MORN repeat
AAAAPHLE_00808 0.0 XK27_09800 I Acyltransferase family
AAAAPHLE_00809 7.1e-37 S Transglycosylase associated protein
AAAAPHLE_00810 2.6e-84
AAAAPHLE_00811 7.2e-23
AAAAPHLE_00812 8.7e-72 asp S Asp23 family, cell envelope-related function
AAAAPHLE_00813 5.3e-72 asp2 S Asp23 family, cell envelope-related function
AAAAPHLE_00814 2.4e-147 Q Fumarylacetoacetate (FAA) hydrolase family
AAAAPHLE_00815 3.7e-161 yjdB S Domain of unknown function (DUF4767)
AAAAPHLE_00816 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
AAAAPHLE_00817 4.1e-101 G Glycogen debranching enzyme
AAAAPHLE_00818 0.0 pepN 3.4.11.2 E aminopeptidase
AAAAPHLE_00819 0.0 N Uncharacterized conserved protein (DUF2075)
AAAAPHLE_00820 2.6e-44 S MazG-like family
AAAAPHLE_00821 8.9e-90 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
AAAAPHLE_00822 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
AAAAPHLE_00824 3.5e-88 S AAA domain
AAAAPHLE_00825 4.5e-140 K sequence-specific DNA binding
AAAAPHLE_00826 2.3e-96 K Helix-turn-helix domain
AAAAPHLE_00827 6.1e-171 K Transcriptional regulator
AAAAPHLE_00828 0.0 1.3.5.4 C FMN_bind
AAAAPHLE_00830 2.3e-81 rmaD K Transcriptional regulator
AAAAPHLE_00831 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AAAAPHLE_00832 2.8e-254 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
AAAAPHLE_00833 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
AAAAPHLE_00834 6.7e-278 pipD E Dipeptidase
AAAAPHLE_00835 2.3e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AAAAPHLE_00836 3.2e-40
AAAAPHLE_00837 4.1e-32 L leucine-zipper of insertion element IS481
AAAAPHLE_00838 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
AAAAPHLE_00839 8.4e-162 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
AAAAPHLE_00840 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
AAAAPHLE_00841 4.3e-138 S NADPH-dependent FMN reductase
AAAAPHLE_00842 3e-179
AAAAPHLE_00843 3.7e-219 yibE S overlaps another CDS with the same product name
AAAAPHLE_00844 3.4e-127 yibF S overlaps another CDS with the same product name
AAAAPHLE_00845 5.7e-103 3.2.2.20 K FR47-like protein
AAAAPHLE_00846 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
AAAAPHLE_00847 5.6e-49
AAAAPHLE_00848 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
AAAAPHLE_00849 6.1e-255 xylP2 G symporter
AAAAPHLE_00850 5.2e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AAAAPHLE_00851 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
AAAAPHLE_00852 0.0 asnB 6.3.5.4 E Asparagine synthase
AAAAPHLE_00853 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
AAAAPHLE_00854 1.3e-120 azlC E branched-chain amino acid
AAAAPHLE_00855 4.4e-35 yyaN K MerR HTH family regulatory protein
AAAAPHLE_00857 1.9e-106
AAAAPHLE_00859 1.4e-117 S Domain of unknown function (DUF4811)
AAAAPHLE_00860 7e-270 lmrB EGP Major facilitator Superfamily
AAAAPHLE_00861 1.7e-84 merR K MerR HTH family regulatory protein
AAAAPHLE_00862 5.8e-58
AAAAPHLE_00863 2e-120 sirR K iron dependent repressor
AAAAPHLE_00864 6e-31 cspC K Cold shock protein
AAAAPHLE_00865 1.5e-130 thrE S Putative threonine/serine exporter
AAAAPHLE_00866 3.3e-43 S Threonine/Serine exporter, ThrE
AAAAPHLE_00867 1.2e-21 S Threonine/Serine exporter, ThrE
AAAAPHLE_00868 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AAAAPHLE_00869 2.3e-119 lssY 3.6.1.27 I phosphatase
AAAAPHLE_00870 2e-154 I alpha/beta hydrolase fold
AAAAPHLE_00871 4.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
AAAAPHLE_00872 4.2e-92 K Transcriptional regulator
AAAAPHLE_00873 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
AAAAPHLE_00874 1.5e-264 lysP E amino acid
AAAAPHLE_00875 4.2e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
AAAAPHLE_00876 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AAAAPHLE_00877 1.6e-217 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AAAAPHLE_00886 6.9e-78 ctsR K Belongs to the CtsR family
AAAAPHLE_00887 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AAAAPHLE_00888 1.5e-109 K Bacterial regulatory proteins, tetR family
AAAAPHLE_00889 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAAAPHLE_00890 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAAAPHLE_00891 1.3e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
AAAAPHLE_00892 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AAAAPHLE_00893 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AAAAPHLE_00894 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AAAAPHLE_00895 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
AAAAPHLE_00896 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AAAAPHLE_00897 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
AAAAPHLE_00898 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AAAAPHLE_00899 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AAAAPHLE_00900 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AAAAPHLE_00901 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AAAAPHLE_00902 1.4e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AAAAPHLE_00903 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AAAAPHLE_00904 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
AAAAPHLE_00905 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AAAAPHLE_00906 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AAAAPHLE_00907 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AAAAPHLE_00908 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AAAAPHLE_00909 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AAAAPHLE_00910 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AAAAPHLE_00911 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AAAAPHLE_00912 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AAAAPHLE_00913 2.2e-24 rpmD J Ribosomal protein L30
AAAAPHLE_00914 6.3e-70 rplO J Binds to the 23S rRNA
AAAAPHLE_00915 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AAAAPHLE_00916 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AAAAPHLE_00917 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AAAAPHLE_00918 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AAAAPHLE_00919 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AAAAPHLE_00920 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAAAPHLE_00921 2.1e-61 rplQ J Ribosomal protein L17
AAAAPHLE_00922 7e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AAAAPHLE_00923 1.1e-93 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
AAAAPHLE_00924 1.4e-86 ynhH S NusG domain II
AAAAPHLE_00925 0.0 ndh 1.6.99.3 C NADH dehydrogenase
AAAAPHLE_00926 3.5e-142 cad S FMN_bind
AAAAPHLE_00927 1.5e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AAAAPHLE_00928 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AAAAPHLE_00929 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AAAAPHLE_00930 5e-145 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AAAAPHLE_00931 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AAAAPHLE_00932 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AAAAPHLE_00933 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
AAAAPHLE_00934 1.7e-162 degV S Uncharacterised protein, DegV family COG1307
AAAAPHLE_00935 2.2e-183 ywhK S Membrane
AAAAPHLE_00936 2.5e-203 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
AAAAPHLE_00937 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AAAAPHLE_00938 8.3e-165 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAAAPHLE_00939 5.2e-184 aroF 2.5.1.54 E DAHP synthetase I family
AAAAPHLE_00940 2.6e-197 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AAAAPHLE_00941 2.2e-200 P Sodium:sulfate symporter transmembrane region
AAAAPHLE_00942 4.1e-53 yitW S Iron-sulfur cluster assembly protein
AAAAPHLE_00943 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
AAAAPHLE_00944 4.4e-177 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
AAAAPHLE_00945 9.4e-197 K Helix-turn-helix domain
AAAAPHLE_00946 3.6e-154 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
AAAAPHLE_00947 4.5e-132 mntB 3.6.3.35 P ABC transporter
AAAAPHLE_00948 1.4e-140 mtsB U ABC 3 transport family
AAAAPHLE_00949 1.3e-173 sitA P Belongs to the bacterial solute-binding protein 9 family
AAAAPHLE_00950 3.1e-50
AAAAPHLE_00951 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AAAAPHLE_00952 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
AAAAPHLE_00953 2.9e-179 citR K sugar-binding domain protein
AAAAPHLE_00954 7.9e-208 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
AAAAPHLE_00955 3.3e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AAAAPHLE_00956 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
AAAAPHLE_00957 2.7e-163 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
AAAAPHLE_00958 7.8e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
AAAAPHLE_00959 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AAAAPHLE_00960 2.7e-263 frdC 1.3.5.4 C FAD binding domain
AAAAPHLE_00961 1.2e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
AAAAPHLE_00962 1.1e-161 mleR K LysR family transcriptional regulator
AAAAPHLE_00963 7.5e-166 mleR K LysR family
AAAAPHLE_00964 3.6e-307 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
AAAAPHLE_00965 1.4e-165 mleP S Sodium Bile acid symporter family
AAAAPHLE_00966 5.8e-253 yfnA E Amino Acid
AAAAPHLE_00967 3e-99 S ECF transporter, substrate-specific component
AAAAPHLE_00968 1.8e-23
AAAAPHLE_00969 7.5e-302 S Alpha beta
AAAAPHLE_00970 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
AAAAPHLE_00971 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
AAAAPHLE_00972 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
AAAAPHLE_00973 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AAAAPHLE_00974 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
AAAAPHLE_00975 2.3e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AAAAPHLE_00976 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
AAAAPHLE_00977 3.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
AAAAPHLE_00978 5.8e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
AAAAPHLE_00979 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AAAAPHLE_00980 1e-93 S UPF0316 protein
AAAAPHLE_00981 4.9e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AAAAPHLE_00982 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AAAAPHLE_00983 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AAAAPHLE_00984 1.8e-196 camS S sex pheromone
AAAAPHLE_00985 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAAAPHLE_00986 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AAAAPHLE_00987 2.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAAAPHLE_00988 1e-190 yegS 2.7.1.107 G Lipid kinase
AAAAPHLE_00989 1.2e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AAAAPHLE_00990 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
AAAAPHLE_00991 0.0 yfgQ P E1-E2 ATPase
AAAAPHLE_00992 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_00993 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
AAAAPHLE_00994 6.7e-151 gntR K rpiR family
AAAAPHLE_00995 1.1e-144 lys M Glycosyl hydrolases family 25
AAAAPHLE_00996 1.1e-62 S Domain of unknown function (DUF4828)
AAAAPHLE_00997 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
AAAAPHLE_00998 8.4e-190 mocA S Oxidoreductase
AAAAPHLE_00999 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
AAAAPHLE_01001 2.3e-75 T Universal stress protein family
AAAAPHLE_01002 3.6e-241 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_01003 2.3e-164 S Alpha/beta hydrolase of unknown function (DUF915)
AAAAPHLE_01005 1.3e-73
AAAAPHLE_01006 5e-107
AAAAPHLE_01007 5.1e-161 O Holliday junction DNA helicase ruvB N-terminus
AAAAPHLE_01008 1.5e-226 O Subtilase family
AAAAPHLE_01009 4.9e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
AAAAPHLE_01010 6.1e-216 pbpX1 V Beta-lactamase
AAAAPHLE_01011 1.3e-207 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AAAAPHLE_01012 1.3e-157 yihY S Belongs to the UPF0761 family
AAAAPHLE_01013 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AAAAPHLE_01014 3.4e-32 waaB GT4 M Glycosyl transferases group 1
AAAAPHLE_01016 6.5e-126 epsB M biosynthesis protein
AAAAPHLE_01017 3e-128 ywqD 2.7.10.1 D Capsular exopolysaccharide family
AAAAPHLE_01018 6.4e-137 ywqE 3.1.3.48 GM PHP domain protein
AAAAPHLE_01019 2.8e-85 rfbP M Bacterial sugar transferase
AAAAPHLE_01020 2e-121 traA L MobA MobL family protein
AAAAPHLE_01021 2.6e-147 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AAAAPHLE_01022 6.7e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AAAAPHLE_01023 5.5e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AAAAPHLE_01024 8.4e-151 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AAAAPHLE_01025 2.4e-64 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
AAAAPHLE_01026 3.2e-121 rfbP M Bacterial sugar transferase
AAAAPHLE_01027 3.8e-53
AAAAPHLE_01028 7.3e-33 S Protein of unknown function (DUF2922)
AAAAPHLE_01029 7e-30
AAAAPHLE_01030 6.2e-25
AAAAPHLE_01031 1.3e-99 K DNA-templated transcription, initiation
AAAAPHLE_01032 2.1e-126
AAAAPHLE_01033 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
AAAAPHLE_01034 4.1e-106 ygaC J Belongs to the UPF0374 family
AAAAPHLE_01035 1.5e-133 cwlO M NlpC/P60 family
AAAAPHLE_01036 7.8e-48 K sequence-specific DNA binding
AAAAPHLE_01037 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
AAAAPHLE_01038 4.3e-147 pbpX V Beta-lactamase
AAAAPHLE_01039 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
AAAAPHLE_01040 9.3e-188 yueF S AI-2E family transporter
AAAAPHLE_01041 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
AAAAPHLE_01042 9.5e-213 gntP EG Gluconate
AAAAPHLE_01043 4.6e-293 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
AAAAPHLE_01044 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
AAAAPHLE_01045 3.4e-255 gor 1.8.1.7 C Glutathione reductase
AAAAPHLE_01046 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AAAAPHLE_01047 5.9e-274
AAAAPHLE_01048 9.4e-197 M MucBP domain
AAAAPHLE_01049 7.1e-161 lysR5 K LysR substrate binding domain
AAAAPHLE_01050 5.5e-126 yxaA S membrane transporter protein
AAAAPHLE_01051 3.2e-57 ywjH S Protein of unknown function (DUF1634)
AAAAPHLE_01052 1.5e-308 oppA E ABC transporter, substratebinding protein
AAAAPHLE_01053 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAAAPHLE_01054 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AAAAPHLE_01055 9.2e-203 oppD P Belongs to the ABC transporter superfamily
AAAAPHLE_01056 6.8e-181 oppF P Belongs to the ABC transporter superfamily
AAAAPHLE_01057 1e-63 K Winged helix DNA-binding domain
AAAAPHLE_01058 1.6e-102 L Integrase
AAAAPHLE_01059 0.0 clpE O Belongs to the ClpA ClpB family
AAAAPHLE_01060 6.5e-30
AAAAPHLE_01061 2.7e-39 ptsH G phosphocarrier protein HPR
AAAAPHLE_01062 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AAAAPHLE_01063 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
AAAAPHLE_01064 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
AAAAPHLE_01065 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AAAAPHLE_01066 1.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AAAAPHLE_01067 7.7e-227 patA 2.6.1.1 E Aminotransferase
AAAAPHLE_01068 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
AAAAPHLE_01069 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AAAAPHLE_01075 5.1e-08
AAAAPHLE_01081 4.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
AAAAPHLE_01082 1.8e-182 P secondary active sulfate transmembrane transporter activity
AAAAPHLE_01083 9e-95
AAAAPHLE_01084 2e-94 K Acetyltransferase (GNAT) domain
AAAAPHLE_01085 8.6e-156 T Calcineurin-like phosphoesterase superfamily domain
AAAAPHLE_01086 3.4e-115 rhaS6 K helix_turn_helix, arabinose operon control protein
AAAAPHLE_01087 1.9e-145 I Carboxylesterase family
AAAAPHLE_01088 4.3e-156 yhjX P Major Facilitator Superfamily
AAAAPHLE_01089 7.3e-113 bglK_1 GK ROK family
AAAAPHLE_01090 3.4e-231 mntH P H( )-stimulated, divalent metal cation uptake system
AAAAPHLE_01091 3.8e-187 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
AAAAPHLE_01092 1.9e-256 mmuP E amino acid
AAAAPHLE_01093 2.2e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
AAAAPHLE_01094 1.3e-292 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
AAAAPHLE_01095 1.6e-121
AAAAPHLE_01096 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AAAAPHLE_01097 1.4e-278 bmr3 EGP Major facilitator Superfamily
AAAAPHLE_01098 1.7e-128 N Cell shape-determining protein MreB
AAAAPHLE_01099 0.0 S Pfam Methyltransferase
AAAAPHLE_01100 2.6e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
AAAAPHLE_01101 2e-296 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
AAAAPHLE_01102 4.2e-29
AAAAPHLE_01103 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
AAAAPHLE_01104 3e-124 3.6.1.27 I Acid phosphatase homologues
AAAAPHLE_01105 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AAAAPHLE_01106 4.3e-300 ytgP S Polysaccharide biosynthesis protein
AAAAPHLE_01107 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AAAAPHLE_01108 6.4e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AAAAPHLE_01109 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
AAAAPHLE_01110 4.1e-84 uspA T Belongs to the universal stress protein A family
AAAAPHLE_01111 1.8e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
AAAAPHLE_01112 6.4e-171 ugpA U Binding-protein-dependent transport system inner membrane component
AAAAPHLE_01113 5.4e-150 ugpE G ABC transporter permease
AAAAPHLE_01114 1.3e-259 ugpB G Bacterial extracellular solute-binding protein
AAAAPHLE_01115 3.8e-125 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AAAAPHLE_01116 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
AAAAPHLE_01117 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AAAAPHLE_01118 5.1e-179 XK27_06930 V domain protein
AAAAPHLE_01120 1.8e-125 V Transport permease protein
AAAAPHLE_01121 8.8e-156 V ABC transporter
AAAAPHLE_01122 1.7e-174 K LytTr DNA-binding domain
AAAAPHLE_01124 2.4e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAAAPHLE_01125 1.6e-64 K helix_turn_helix, mercury resistance
AAAAPHLE_01126 3.5e-117 GM NAD(P)H-binding
AAAAPHLE_01127 2.1e-158 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AAAAPHLE_01128 2.2e-148 S Sucrose-6F-phosphate phosphohydrolase
AAAAPHLE_01129 1.7e-108
AAAAPHLE_01130 2.2e-224 pltK 2.7.13.3 T GHKL domain
AAAAPHLE_01131 1.6e-137 pltR K LytTr DNA-binding domain
AAAAPHLE_01132 4.5e-55
AAAAPHLE_01133 2.5e-59
AAAAPHLE_01134 8.7e-114 S CAAX protease self-immunity
AAAAPHLE_01135 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
AAAAPHLE_01136 1e-90
AAAAPHLE_01137 2.5e-46
AAAAPHLE_01138 0.0 uvrA2 L ABC transporter
AAAAPHLE_01141 3e-56
AAAAPHLE_01142 3.5e-10
AAAAPHLE_01143 2.1e-180
AAAAPHLE_01144 1.9e-89 gtcA S Teichoic acid glycosylation protein
AAAAPHLE_01145 1.3e-34 S Protein of unknown function (DUF1516)
AAAAPHLE_01146 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
AAAAPHLE_01147 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AAAAPHLE_01148 9.4e-308 S Protein conserved in bacteria
AAAAPHLE_01149 9.7e-230 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
AAAAPHLE_01150 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
AAAAPHLE_01151 4.2e-175 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
AAAAPHLE_01152 1.8e-304 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
AAAAPHLE_01153 0.0 yfbS P Sodium:sulfate symporter transmembrane region
AAAAPHLE_01154 2.1e-244 dinF V MatE
AAAAPHLE_01155 1.9e-31
AAAAPHLE_01158 2.7e-79 elaA S Acetyltransferase (GNAT) domain
AAAAPHLE_01159 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
AAAAPHLE_01160 7.2e-83
AAAAPHLE_01161 0.0 yhcA V MacB-like periplasmic core domain
AAAAPHLE_01162 9.9e-107
AAAAPHLE_01163 0.0 K PRD domain
AAAAPHLE_01164 2.4e-62 S Domain of unknown function (DUF3284)
AAAAPHLE_01165 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
AAAAPHLE_01166 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
AAAAPHLE_01167 6.1e-220 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_01168 9.7e-288 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_01169 1.5e-209 EGP Major facilitator Superfamily
AAAAPHLE_01170 1e-113 M ErfK YbiS YcfS YnhG
AAAAPHLE_01171 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AAAAPHLE_01172 3.5e-282 ydfD K Alanine-glyoxylate amino-transferase
AAAAPHLE_01173 4e-102 argO S LysE type translocator
AAAAPHLE_01174 3.2e-214 arcT 2.6.1.1 E Aminotransferase
AAAAPHLE_01175 4.4e-77 argR K Regulates arginine biosynthesis genes
AAAAPHLE_01176 2.9e-12
AAAAPHLE_01177 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AAAAPHLE_01178 1e-54 yheA S Belongs to the UPF0342 family
AAAAPHLE_01179 4.1e-231 yhaO L Ser Thr phosphatase family protein
AAAAPHLE_01180 0.0 L AAA domain
AAAAPHLE_01181 3.2e-186 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
AAAAPHLE_01182 9.7e-214
AAAAPHLE_01183 4e-181 3.4.21.102 M Peptidase family S41
AAAAPHLE_01184 1.2e-177 K LysR substrate binding domain
AAAAPHLE_01185 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
AAAAPHLE_01186 0.0 1.3.5.4 C FAD binding domain
AAAAPHLE_01187 1.7e-99
AAAAPHLE_01188 1.6e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
AAAAPHLE_01189 6.1e-185 ykoT GT2 M Glycosyl transferase family 2
AAAAPHLE_01190 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AAAAPHLE_01191 1.7e-19 S NUDIX domain
AAAAPHLE_01192 0.0 S membrane
AAAAPHLE_01193 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AAAAPHLE_01194 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
AAAAPHLE_01195 3.1e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
AAAAPHLE_01196 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
AAAAPHLE_01197 9.3e-106 GBS0088 S Nucleotidyltransferase
AAAAPHLE_01198 1.4e-106
AAAAPHLE_01199 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
AAAAPHLE_01200 1.3e-111 K Bacterial regulatory proteins, tetR family
AAAAPHLE_01201 4.7e-241 npr 1.11.1.1 C NADH oxidase
AAAAPHLE_01202 0.0
AAAAPHLE_01203 2.7e-61
AAAAPHLE_01204 4.2e-192 S Fn3-like domain
AAAAPHLE_01205 1.5e-102 S WxL domain surface cell wall-binding
AAAAPHLE_01206 3.5e-78 S WxL domain surface cell wall-binding
AAAAPHLE_01207 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AAAAPHLE_01208 2e-42
AAAAPHLE_01209 9.9e-82 hit FG histidine triad
AAAAPHLE_01210 1.6e-134 ecsA V ABC transporter, ATP-binding protein
AAAAPHLE_01211 9e-223 ecsB U ABC transporter
AAAAPHLE_01212 9.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
AAAAPHLE_01213 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AAAAPHLE_01214 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
AAAAPHLE_01215 6.2e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AAAAPHLE_01216 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
AAAAPHLE_01217 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AAAAPHLE_01218 7.9e-21 S Virus attachment protein p12 family
AAAAPHLE_01219 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
AAAAPHLE_01220 5e-34 feoA P FeoA domain
AAAAPHLE_01221 4.2e-144 sufC O FeS assembly ATPase SufC
AAAAPHLE_01222 3.8e-243 sufD O FeS assembly protein SufD
AAAAPHLE_01223 2.6e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AAAAPHLE_01224 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
AAAAPHLE_01225 1.4e-272 sufB O assembly protein SufB
AAAAPHLE_01226 3.2e-179 fecB P Periplasmic binding protein
AAAAPHLE_01227 1.3e-137 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
AAAAPHLE_01228 2.2e-166 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAAAPHLE_01229 5.8e-82 fld C NrdI Flavodoxin like
AAAAPHLE_01230 4.5e-70 moaE 2.8.1.12 H MoaE protein
AAAAPHLE_01231 2.7e-33 moaD 2.8.1.12 H ThiS family
AAAAPHLE_01232 1.3e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AAAAPHLE_01233 2.5e-217 narK P Transporter, major facilitator family protein
AAAAPHLE_01234 8.8e-59 yitW S Iron-sulfur cluster assembly protein
AAAAPHLE_01235 2.1e-157 hipB K Helix-turn-helix
AAAAPHLE_01236 1.1e-161 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
AAAAPHLE_01237 1.5e-183
AAAAPHLE_01238 1.5e-49
AAAAPHLE_01239 4e-116 nreC K PFAM regulatory protein LuxR
AAAAPHLE_01240 3.5e-191 comP 2.7.13.3 F Sensor histidine kinase
AAAAPHLE_01241 1.3e-75 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
AAAAPHLE_01242 7.8e-39
AAAAPHLE_01243 2.5e-99 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
AAAAPHLE_01244 7.2e-86 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
AAAAPHLE_01245 4.1e-89 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
AAAAPHLE_01246 8.2e-232 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
AAAAPHLE_01247 3.2e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
AAAAPHLE_01248 9.5e-197 moeB 2.7.7.73, 2.7.7.80 H ThiF family
AAAAPHLE_01249 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AAAAPHLE_01250 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
AAAAPHLE_01251 7.3e-98 narJ C Nitrate reductase delta subunit
AAAAPHLE_01252 2.7e-123 narI 1.7.5.1 C Nitrate reductase
AAAAPHLE_01253 3.9e-176
AAAAPHLE_01254 1.5e-73
AAAAPHLE_01255 7.3e-98 S Protein of unknown function (DUF2975)
AAAAPHLE_01256 1.7e-28 yozG K Transcriptional regulator
AAAAPHLE_01257 4.5e-121 ybhL S Belongs to the BI1 family
AAAAPHLE_01258 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAAAPHLE_01259 7.6e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AAAAPHLE_01260 6.6e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AAAAPHLE_01261 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AAAAPHLE_01262 5.5e-248 dnaB L replication initiation and membrane attachment
AAAAPHLE_01263 3.3e-172 dnaI L Primosomal protein DnaI
AAAAPHLE_01264 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AAAAPHLE_01265 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AAAAPHLE_01266 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AAAAPHLE_01267 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AAAAPHLE_01268 1.1e-55
AAAAPHLE_01269 1.9e-239 yrvN L AAA C-terminal domain
AAAAPHLE_01270 3.6e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
AAAAPHLE_01271 1e-62 hxlR K Transcriptional regulator, HxlR family
AAAAPHLE_01272 1.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
AAAAPHLE_01273 1e-248 pgaC GT2 M Glycosyl transferase
AAAAPHLE_01274 1.3e-79
AAAAPHLE_01275 1.4e-98 yqeG S HAD phosphatase, family IIIA
AAAAPHLE_01276 1.7e-215 yqeH S Ribosome biogenesis GTPase YqeH
AAAAPHLE_01277 1.1e-50 yhbY J RNA-binding protein
AAAAPHLE_01278 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AAAAPHLE_01279 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
AAAAPHLE_01280 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AAAAPHLE_01281 4.4e-140 yqeM Q Methyltransferase
AAAAPHLE_01282 2.2e-218 ylbM S Belongs to the UPF0348 family
AAAAPHLE_01283 1.6e-97 yceD S Uncharacterized ACR, COG1399
AAAAPHLE_01284 3.1e-88 S Peptidase propeptide and YPEB domain
AAAAPHLE_01285 2.9e-129 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AAAAPHLE_01286 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AAAAPHLE_01287 4.2e-245 rarA L recombination factor protein RarA
AAAAPHLE_01288 4.3e-121 K response regulator
AAAAPHLE_01289 3e-306 arlS 2.7.13.3 T Histidine kinase
AAAAPHLE_01290 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
AAAAPHLE_01291 0.0 sbcC L Putative exonuclease SbcCD, C subunit
AAAAPHLE_01292 1.3e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AAAAPHLE_01293 1.1e-93 S SdpI/YhfL protein family
AAAAPHLE_01294 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AAAAPHLE_01295 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AAAAPHLE_01296 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAAAPHLE_01297 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
AAAAPHLE_01298 7.4e-64 yodB K Transcriptional regulator, HxlR family
AAAAPHLE_01299 1.4e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AAAAPHLE_01300 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AAAAPHLE_01301 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AAAAPHLE_01302 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
AAAAPHLE_01303 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AAAAPHLE_01304 2.8e-94 liaI S membrane
AAAAPHLE_01305 4e-75 XK27_02470 K LytTr DNA-binding domain
AAAAPHLE_01306 1.5e-54 yneR S Belongs to the HesB IscA family
AAAAPHLE_01307 0.0 S membrane
AAAAPHLE_01308 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
AAAAPHLE_01309 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AAAAPHLE_01310 1.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AAAAPHLE_01311 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
AAAAPHLE_01312 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
AAAAPHLE_01313 5.7e-180 glk 2.7.1.2 G Glucokinase
AAAAPHLE_01314 6.4e-111 pepE 3.4.13.21 E Belongs to the peptidase S51 family
AAAAPHLE_01315 1.7e-67 yqhL P Rhodanese-like protein
AAAAPHLE_01316 1.2e-22 WQ51_02665 S Protein of unknown function (DUF3042)
AAAAPHLE_01317 2.9e-139 glpQ 3.1.4.46 C phosphodiesterase
AAAAPHLE_01318 9.2e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AAAAPHLE_01319 4.6e-64 glnR K Transcriptional regulator
AAAAPHLE_01320 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
AAAAPHLE_01321 2.6e-161
AAAAPHLE_01322 8.8e-181
AAAAPHLE_01323 4.5e-97 dut S Protein conserved in bacteria
AAAAPHLE_01324 1.6e-55
AAAAPHLE_01325 1.7e-30
AAAAPHLE_01328 5.4e-19
AAAAPHLE_01329 1.8e-89 K Transcriptional regulator
AAAAPHLE_01330 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
AAAAPHLE_01331 3.2e-53 ysxB J Cysteine protease Prp
AAAAPHLE_01332 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AAAAPHLE_01333 1.6e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AAAAPHLE_01334 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AAAAPHLE_01335 3.5e-74 yqhY S Asp23 family, cell envelope-related function
AAAAPHLE_01336 5.8e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAAAPHLE_01337 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AAAAPHLE_01338 9.3e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AAAAPHLE_01339 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AAAAPHLE_01340 6.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AAAAPHLE_01341 9e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AAAAPHLE_01342 7.4e-77 argR K Regulates arginine biosynthesis genes
AAAAPHLE_01343 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
AAAAPHLE_01344 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
AAAAPHLE_01345 1.2e-104 opuCB E ABC transporter permease
AAAAPHLE_01346 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AAAAPHLE_01347 6.4e-106 opuCD P Binding-protein-dependent transport system inner membrane component
AAAAPHLE_01348 4.5e-55
AAAAPHLE_01349 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AAAAPHLE_01350 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AAAAPHLE_01351 4e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AAAAPHLE_01352 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AAAAPHLE_01353 1.9e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AAAAPHLE_01354 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AAAAPHLE_01355 1.7e-134 stp 3.1.3.16 T phosphatase
AAAAPHLE_01356 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
AAAAPHLE_01357 9.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AAAAPHLE_01358 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AAAAPHLE_01359 1.7e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
AAAAPHLE_01360 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AAAAPHLE_01361 1.8e-57 asp S Asp23 family, cell envelope-related function
AAAAPHLE_01362 0.0 yloV S DAK2 domain fusion protein YloV
AAAAPHLE_01363 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AAAAPHLE_01364 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AAAAPHLE_01365 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAAAPHLE_01366 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AAAAPHLE_01367 0.0 smc D Required for chromosome condensation and partitioning
AAAAPHLE_01368 6.6e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AAAAPHLE_01369 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AAAAPHLE_01370 2.9e-220 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AAAAPHLE_01371 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AAAAPHLE_01372 2.6e-39 ylqC S Belongs to the UPF0109 family
AAAAPHLE_01373 2.4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AAAAPHLE_01374 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AAAAPHLE_01375 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AAAAPHLE_01376 1.4e-50
AAAAPHLE_01377 5.1e-161 pelX UW LPXTG-motif cell wall anchor domain protein
AAAAPHLE_01378 5.3e-86
AAAAPHLE_01379 2.4e-136 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
AAAAPHLE_01380 8.1e-272 XK27_00765
AAAAPHLE_01381 1.7e-207 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
AAAAPHLE_01382 2e-52 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
AAAAPHLE_01383 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
AAAAPHLE_01384 5.9e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AAAAPHLE_01385 4.9e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
AAAAPHLE_01386 4.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
AAAAPHLE_01387 2.1e-227 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AAAAPHLE_01388 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AAAAPHLE_01389 2e-97 entB 3.5.1.19 Q Isochorismatase family
AAAAPHLE_01390 1.3e-176 1.6.5.5 C Zinc-binding dehydrogenase
AAAAPHLE_01391 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
AAAAPHLE_01392 4.4e-217 E glutamate:sodium symporter activity
AAAAPHLE_01393 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
AAAAPHLE_01394 2.7e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
AAAAPHLE_01395 8.5e-60 S Protein of unknown function (DUF1648)
AAAAPHLE_01396 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AAAAPHLE_01397 3.8e-179 yneE K Transcriptional regulator
AAAAPHLE_01398 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AAAAPHLE_01399 1.1e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AAAAPHLE_01400 1.3e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAAAPHLE_01401 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
AAAAPHLE_01402 1.2e-126 IQ reductase
AAAAPHLE_01403 1.6e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AAAAPHLE_01404 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AAAAPHLE_01405 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
AAAAPHLE_01406 5.2e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
AAAAPHLE_01407 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AAAAPHLE_01408 6.7e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
AAAAPHLE_01409 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
AAAAPHLE_01410 1.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
AAAAPHLE_01411 2.2e-123 S Protein of unknown function (DUF554)
AAAAPHLE_01412 1.6e-160 K LysR substrate binding domain
AAAAPHLE_01413 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
AAAAPHLE_01414 6.5e-193 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AAAAPHLE_01415 4e-93 K transcriptional regulator
AAAAPHLE_01416 1e-301 norB EGP Major Facilitator
AAAAPHLE_01417 3.4e-139 f42a O Band 7 protein
AAAAPHLE_01418 4.7e-85 S Protein of unknown function with HXXEE motif
AAAAPHLE_01419 2.6e-75 S Protein of unknown function with HXXEE motif
AAAAPHLE_01420 1.7e-11 K Bacterial regulatory proteins, tetR family
AAAAPHLE_01422 3.6e-154 L Integrase core domain
AAAAPHLE_01423 9.8e-39 L Transposase and inactivated derivatives
AAAAPHLE_01426 1.1e-53
AAAAPHLE_01427 1e-150 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
AAAAPHLE_01428 2.9e-113 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
AAAAPHLE_01429 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
AAAAPHLE_01430 7.9e-41
AAAAPHLE_01431 1.9e-67 tspO T TspO/MBR family
AAAAPHLE_01432 6.3e-76 uspA T Belongs to the universal stress protein A family
AAAAPHLE_01433 8e-66 S Protein of unknown function (DUF805)
AAAAPHLE_01434 2e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
AAAAPHLE_01435 3.5e-36
AAAAPHLE_01436 3.1e-14
AAAAPHLE_01437 6.5e-41 S transglycosylase associated protein
AAAAPHLE_01438 4.8e-29 S CsbD-like
AAAAPHLE_01439 9.4e-40
AAAAPHLE_01440 8.6e-281 pipD E Dipeptidase
AAAAPHLE_01441 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
AAAAPHLE_01442 1.3e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AAAAPHLE_01443 1e-170 2.5.1.74 H UbiA prenyltransferase family
AAAAPHLE_01444 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
AAAAPHLE_01445 3.9e-50
AAAAPHLE_01446 2.4e-43
AAAAPHLE_01447 3.7e-257 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AAAAPHLE_01448 1.4e-265 yfnA E Amino Acid
AAAAPHLE_01449 1.2e-149 yitU 3.1.3.104 S hydrolase
AAAAPHLE_01450 1.8e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
AAAAPHLE_01451 7.7e-83 S Domain of unknown function (DUF4767)
AAAAPHLE_01452 1.3e-249 malT G Major Facilitator
AAAAPHLE_01453 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
AAAAPHLE_01454 6.7e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AAAAPHLE_01455 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AAAAPHLE_01456 7.6e-205 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
AAAAPHLE_01457 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AAAAPHLE_01458 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
AAAAPHLE_01459 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AAAAPHLE_01460 2.1e-72 ypmB S protein conserved in bacteria
AAAAPHLE_01461 4.3e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AAAAPHLE_01462 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
AAAAPHLE_01463 1.3e-128 dnaD L Replication initiation and membrane attachment
AAAAPHLE_01465 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AAAAPHLE_01466 2e-99 metI P ABC transporter permease
AAAAPHLE_01467 2.7e-157 metQ_4 P Belongs to the nlpA lipoprotein family
AAAAPHLE_01468 7.6e-83 uspA T Universal stress protein family
AAAAPHLE_01469 1.6e-302 ftpA P Binding-protein-dependent transport system inner membrane component
AAAAPHLE_01470 1.7e-182 ftpB P Bacterial extracellular solute-binding protein
AAAAPHLE_01471 7.5e-145 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
AAAAPHLE_01472 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
AAAAPHLE_01473 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AAAAPHLE_01474 8.3e-110 ypsA S Belongs to the UPF0398 family
AAAAPHLE_01475 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AAAAPHLE_01477 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AAAAPHLE_01478 3.4e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
AAAAPHLE_01479 3e-243 P Major Facilitator Superfamily
AAAAPHLE_01480 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
AAAAPHLE_01481 4.4e-73 S SnoaL-like domain
AAAAPHLE_01482 1.8e-243 M Glycosyltransferase, group 2 family protein
AAAAPHLE_01483 2.5e-26 mccF V LD-carboxypeptidase
AAAAPHLE_01484 1.1e-163 mccF V LD-carboxypeptidase
AAAAPHLE_01485 1.4e-78 K Acetyltransferase (GNAT) domain
AAAAPHLE_01486 6.9e-240 M hydrolase, family 25
AAAAPHLE_01487 6.2e-182 mccF 3.4.17.13 V LD-carboxypeptidase
AAAAPHLE_01488 9.2e-125
AAAAPHLE_01489 2.8e-120 3.6.3.35 P ATPases associated with a variety of cellular activities
AAAAPHLE_01490 2.1e-194
AAAAPHLE_01491 3.4e-146 S hydrolase activity, acting on ester bonds
AAAAPHLE_01492 3.2e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
AAAAPHLE_01493 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
AAAAPHLE_01494 3.3e-62 esbA S Family of unknown function (DUF5322)
AAAAPHLE_01495 4.1e-295 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AAAAPHLE_01496 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AAAAPHLE_01497 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AAAAPHLE_01498 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AAAAPHLE_01499 2.8e-207 carA 6.3.5.5 F Belongs to the CarA family
AAAAPHLE_01500 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AAAAPHLE_01501 4.4e-287 S Bacterial membrane protein, YfhO
AAAAPHLE_01502 6.4e-113 pgm5 G Phosphoglycerate mutase family
AAAAPHLE_01503 3.5e-32 frataxin S Domain of unknown function (DU1801)
AAAAPHLE_01505 1.1e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
AAAAPHLE_01506 1.7e-46 S LuxR family transcriptional regulator
AAAAPHLE_01507 8.6e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
AAAAPHLE_01509 1.2e-91 3.6.1.55 F NUDIX domain
AAAAPHLE_01510 2.4e-164 V ABC transporter, ATP-binding protein
AAAAPHLE_01511 3.2e-37 S ABC-2 family transporter protein
AAAAPHLE_01512 4.6e-56 S ABC-2 family transporter protein
AAAAPHLE_01513 0.0 FbpA K Fibronectin-binding protein
AAAAPHLE_01514 1.9e-66 K Transcriptional regulator
AAAAPHLE_01515 7e-161 degV S EDD domain protein, DegV family
AAAAPHLE_01516 3.2e-77 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
AAAAPHLE_01517 1.3e-131 S Protein of unknown function (DUF975)
AAAAPHLE_01518 4.3e-10
AAAAPHLE_01519 1.4e-49
AAAAPHLE_01520 3.3e-149 2.7.7.12 C Domain of unknown function (DUF4931)
AAAAPHLE_01521 8.9e-207 pmrB EGP Major facilitator Superfamily
AAAAPHLE_01522 4.6e-12
AAAAPHLE_01523 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
AAAAPHLE_01524 4.6e-129 yejC S Protein of unknown function (DUF1003)
AAAAPHLE_01525 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
AAAAPHLE_01526 2.1e-244 cycA E Amino acid permease
AAAAPHLE_01527 1.8e-116
AAAAPHLE_01528 4.1e-59
AAAAPHLE_01529 1.4e-279 lldP C L-lactate permease
AAAAPHLE_01530 7.4e-226
AAAAPHLE_01531 4.4e-109 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
AAAAPHLE_01532 8.6e-196 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
AAAAPHLE_01533 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
AAAAPHLE_01534 8.5e-93 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
AAAAPHLE_01535 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
AAAAPHLE_01536 1.2e-239 gshR1 1.8.1.7 C Glutathione reductase
AAAAPHLE_01537 2.1e-51
AAAAPHLE_01538 9.3e-242 M Glycosyl transferase family group 2
AAAAPHLE_01539 2.8e-274 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AAAAPHLE_01540 4.6e-157 xerD L Phage integrase, N-terminal SAM-like domain
AAAAPHLE_01541 4.2e-32 S YozE SAM-like fold
AAAAPHLE_01542 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAAAPHLE_01543 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
AAAAPHLE_01544 1.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
AAAAPHLE_01545 1.2e-177 K Transcriptional regulator
AAAAPHLE_01546 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AAAAPHLE_01547 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AAAAPHLE_01548 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AAAAPHLE_01549 1.1e-169 lacX 5.1.3.3 G Aldose 1-epimerase
AAAAPHLE_01550 1.5e-256 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AAAAPHLE_01551 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AAAAPHLE_01552 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
AAAAPHLE_01553 9.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AAAAPHLE_01554 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AAAAPHLE_01555 1.2e-157 dprA LU DNA protecting protein DprA
AAAAPHLE_01556 3.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AAAAPHLE_01557 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AAAAPHLE_01559 2e-227 XK27_05470 E Methionine synthase
AAAAPHLE_01560 2.3e-170 cpsY K Transcriptional regulator, LysR family
AAAAPHLE_01561 2.7e-174 L restriction endonuclease
AAAAPHLE_01562 9.4e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
AAAAPHLE_01563 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
AAAAPHLE_01564 5.6e-251 emrY EGP Major facilitator Superfamily
AAAAPHLE_01565 7.8e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
AAAAPHLE_01566 3.4e-35 yozE S Belongs to the UPF0346 family
AAAAPHLE_01567 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
AAAAPHLE_01568 5.1e-149 ypmR E GDSL-like Lipase/Acylhydrolase
AAAAPHLE_01569 5.1e-148 DegV S EDD domain protein, DegV family
AAAAPHLE_01570 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AAAAPHLE_01571 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AAAAPHLE_01572 0.0 yfmR S ABC transporter, ATP-binding protein
AAAAPHLE_01573 9.6e-85
AAAAPHLE_01574 2.5e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AAAAPHLE_01575 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AAAAPHLE_01576 2e-149 3.1.3.102, 3.1.3.104 S hydrolase
AAAAPHLE_01577 2.1e-206 S Tetratricopeptide repeat protein
AAAAPHLE_01578 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AAAAPHLE_01579 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AAAAPHLE_01580 8.4e-211 rpsA 1.17.7.4 J Ribosomal protein S1
AAAAPHLE_01581 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AAAAPHLE_01582 2e-19 M Lysin motif
AAAAPHLE_01583 5.8e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
AAAAPHLE_01584 4.4e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
AAAAPHLE_01585 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AAAAPHLE_01586 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AAAAPHLE_01587 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AAAAPHLE_01588 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AAAAPHLE_01589 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AAAAPHLE_01590 1.1e-164 xerD D recombinase XerD
AAAAPHLE_01591 2.9e-170 cvfB S S1 domain
AAAAPHLE_01592 1.5e-74 yeaL S Protein of unknown function (DUF441)
AAAAPHLE_01593 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AAAAPHLE_01594 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AAAAPHLE_01595 0.0 dnaE 2.7.7.7 L DNA polymerase
AAAAPHLE_01596 7.3e-29 S Protein of unknown function (DUF2929)
AAAAPHLE_01597 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AAAAPHLE_01598 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AAAAPHLE_01599 1.2e-196 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AAAAPHLE_01600 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
AAAAPHLE_01601 2.1e-219 M O-Antigen ligase
AAAAPHLE_01602 2e-119 drrB U ABC-2 type transporter
AAAAPHLE_01603 4.3e-164 drrA V ABC transporter
AAAAPHLE_01604 6.9e-84 K helix_turn_helix multiple antibiotic resistance protein
AAAAPHLE_01605 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
AAAAPHLE_01606 1.2e-38 P Rhodanese Homology Domain
AAAAPHLE_01607 8.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
AAAAPHLE_01608 7.2e-184
AAAAPHLE_01609 3.4e-179 I transferase activity, transferring acyl groups other than amino-acyl groups
AAAAPHLE_01610 5.1e-20 I transferase activity, transferring acyl groups other than amino-acyl groups
AAAAPHLE_01611 4.5e-180 C Zinc-binding dehydrogenase
AAAAPHLE_01612 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
AAAAPHLE_01613 6.8e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AAAAPHLE_01614 6.5e-241 EGP Major facilitator Superfamily
AAAAPHLE_01615 4.3e-77 K Transcriptional regulator
AAAAPHLE_01616 1.4e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
AAAAPHLE_01617 1.3e-54 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AAAAPHLE_01618 4.2e-158 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AAAAPHLE_01619 1.8e-136 K DeoR C terminal sensor domain
AAAAPHLE_01620 1e-89 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
AAAAPHLE_01621 9.1e-71 yneH 1.20.4.1 P ArsC family
AAAAPHLE_01622 4.1e-68 S Protein of unknown function (DUF1722)
AAAAPHLE_01623 2e-112 GM epimerase
AAAAPHLE_01624 0.0 CP_1020 S Zinc finger, swim domain protein
AAAAPHLE_01625 1.3e-117 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
AAAAPHLE_01626 6.4e-76 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
AAAAPHLE_01627 6.5e-128 K Helix-turn-helix domain, rpiR family
AAAAPHLE_01628 3.4e-160 S Alpha beta hydrolase
AAAAPHLE_01629 2e-112 GM NmrA-like family
AAAAPHLE_01630 9.8e-79 S Uncharacterized protein conserved in bacteria (DUF2255)
AAAAPHLE_01631 1.9e-161 K Transcriptional regulator
AAAAPHLE_01632 6.7e-173 C nadph quinone reductase
AAAAPHLE_01633 1.8e-13 S Alpha beta hydrolase
AAAAPHLE_01634 1.2e-137 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AAAAPHLE_01635 9.6e-118 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
AAAAPHLE_01636 1.2e-103 desR K helix_turn_helix, Lux Regulon
AAAAPHLE_01637 2.2e-204 desK 2.7.13.3 T Histidine kinase
AAAAPHLE_01638 1.3e-134 yvfS V ABC-2 type transporter
AAAAPHLE_01639 3.3e-158 yvfR V ABC transporter
AAAAPHLE_01641 6e-82 K Acetyltransferase (GNAT) domain
AAAAPHLE_01642 1.6e-79 K MarR family
AAAAPHLE_01643 3.8e-114 S Psort location CytoplasmicMembrane, score
AAAAPHLE_01644 3.9e-162 V ABC transporter, ATP-binding protein
AAAAPHLE_01645 7.5e-127 S ABC-2 family transporter protein
AAAAPHLE_01646 4.5e-194
AAAAPHLE_01647 2e-202
AAAAPHLE_01648 2.2e-165 ytrB V ABC transporter, ATP-binding protein
AAAAPHLE_01649 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
AAAAPHLE_01650 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AAAAPHLE_01651 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AAAAPHLE_01652 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AAAAPHLE_01653 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AAAAPHLE_01654 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
AAAAPHLE_01655 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AAAAPHLE_01656 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
AAAAPHLE_01657 6.6e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AAAAPHLE_01658 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
AAAAPHLE_01659 1.3e-70 yqeY S YqeY-like protein
AAAAPHLE_01660 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AAAAPHLE_01661 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AAAAPHLE_01662 1.7e-128 C Enoyl-(Acyl carrier protein) reductase
AAAAPHLE_01663 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AAAAPHLE_01664 2.9e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
AAAAPHLE_01665 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AAAAPHLE_01666 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAAAPHLE_01667 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AAAAPHLE_01668 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
AAAAPHLE_01669 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AAAAPHLE_01670 5.1e-164 yniA G Fructosamine kinase
AAAAPHLE_01671 2.2e-116 3.1.3.18 J HAD-hyrolase-like
AAAAPHLE_01672 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AAAAPHLE_01673 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AAAAPHLE_01674 2.1e-57
AAAAPHLE_01675 2.4e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AAAAPHLE_01676 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
AAAAPHLE_01677 8.8e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
AAAAPHLE_01678 1.4e-49
AAAAPHLE_01679 1.4e-49
AAAAPHLE_01680 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AAAAPHLE_01681 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AAAAPHLE_01682 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AAAAPHLE_01683 2.5e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
AAAAPHLE_01684 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AAAAPHLE_01685 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
AAAAPHLE_01686 4.4e-198 pbpX2 V Beta-lactamase
AAAAPHLE_01687 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AAAAPHLE_01688 0.0 dnaK O Heat shock 70 kDa protein
AAAAPHLE_01689 3e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AAAAPHLE_01690 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AAAAPHLE_01691 2.5e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
AAAAPHLE_01692 4.9e-190 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AAAAPHLE_01693 9.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AAAAPHLE_01694 1.7e-85 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AAAAPHLE_01695 7.2e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
AAAAPHLE_01696 6.5e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AAAAPHLE_01697 8.5e-93
AAAAPHLE_01698 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AAAAPHLE_01699 2.5e-264 ydiN 5.4.99.5 G Major Facilitator
AAAAPHLE_01700 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AAAAPHLE_01701 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AAAAPHLE_01702 1.1e-47 ylxQ J ribosomal protein
AAAAPHLE_01703 9.5e-49 ylxR K Protein of unknown function (DUF448)
AAAAPHLE_01704 3.3e-217 nusA K Participates in both transcription termination and antitermination
AAAAPHLE_01705 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
AAAAPHLE_01706 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AAAAPHLE_01707 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AAAAPHLE_01708 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AAAAPHLE_01709 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
AAAAPHLE_01710 6.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AAAAPHLE_01711 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AAAAPHLE_01712 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AAAAPHLE_01713 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AAAAPHLE_01714 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
AAAAPHLE_01715 4.7e-134 S Haloacid dehalogenase-like hydrolase
AAAAPHLE_01716 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAAAPHLE_01717 1.8e-39 yazA L GIY-YIG catalytic domain protein
AAAAPHLE_01718 4.2e-133 yabB 2.1.1.223 L Methyltransferase small domain
AAAAPHLE_01719 1.2e-117 plsC 2.3.1.51 I Acyltransferase
AAAAPHLE_01720 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
AAAAPHLE_01721 2.9e-36 ynzC S UPF0291 protein
AAAAPHLE_01722 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AAAAPHLE_01723 2.9e-87
AAAAPHLE_01724 9.3e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
AAAAPHLE_01725 5.4e-76
AAAAPHLE_01726 4.3e-65
AAAAPHLE_01727 2.1e-08 S Short C-terminal domain
AAAAPHLE_01728 2.6e-20 S Short C-terminal domain
AAAAPHLE_01731 2.9e-43 L HTH-like domain
AAAAPHLE_01732 3.4e-36 L transposase activity
AAAAPHLE_01733 3.8e-61 L Belongs to the 'phage' integrase family
AAAAPHLE_01736 1.6e-31
AAAAPHLE_01737 1.9e-141 Q Methyltransferase
AAAAPHLE_01738 8.5e-57 ybjQ S Belongs to the UPF0145 family
AAAAPHLE_01739 7.2e-212 EGP Major facilitator Superfamily
AAAAPHLE_01740 1e-102 K Helix-turn-helix domain
AAAAPHLE_01741 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AAAAPHLE_01742 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
AAAAPHLE_01743 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
AAAAPHLE_01744 2.8e-140 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AAAAPHLE_01745 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AAAAPHLE_01746 1.2e-45
AAAAPHLE_01747 6.9e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AAAAPHLE_01748 1.5e-135 fruR K DeoR C terminal sensor domain
AAAAPHLE_01749 5.1e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AAAAPHLE_01750 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
AAAAPHLE_01751 6.5e-251 cpdA S Calcineurin-like phosphoesterase
AAAAPHLE_01752 4.1e-262 cps4J S Polysaccharide biosynthesis protein
AAAAPHLE_01753 4.7e-174 cps4I M Glycosyltransferase like family 2
AAAAPHLE_01754 1.2e-228
AAAAPHLE_01755 8.9e-179 cps4G M Glycosyltransferase Family 4
AAAAPHLE_01756 4.6e-194 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
AAAAPHLE_01757 1.8e-127 tuaA M Bacterial sugar transferase
AAAAPHLE_01758 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
AAAAPHLE_01759 3.8e-90 ywqE 3.1.3.48 GM PHP domain protein
AAAAPHLE_01760 6.2e-39 ywqE 3.1.3.48 GM PHP domain protein
AAAAPHLE_01761 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
AAAAPHLE_01762 2.9e-126 epsB M biosynthesis protein
AAAAPHLE_01763 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AAAAPHLE_01764 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AAAAPHLE_01765 9.2e-270 glnPH2 P ABC transporter permease
AAAAPHLE_01766 4.3e-22
AAAAPHLE_01767 9.9e-73 S Iron-sulphur cluster biosynthesis
AAAAPHLE_01768 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
AAAAPHLE_01769 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
AAAAPHLE_01770 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AAAAPHLE_01771 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AAAAPHLE_01772 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AAAAPHLE_01773 2.5e-156 S Tetratricopeptide repeat
AAAAPHLE_01774 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AAAAPHLE_01775 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAAAPHLE_01776 3.7e-192 mdtG EGP Major Facilitator Superfamily
AAAAPHLE_01777 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AAAAPHLE_01778 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
AAAAPHLE_01779 1.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
AAAAPHLE_01780 0.0 comEC S Competence protein ComEC
AAAAPHLE_01781 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
AAAAPHLE_01782 1.2e-121 comEA L Competence protein ComEA
AAAAPHLE_01783 9.6e-197 ylbL T Belongs to the peptidase S16 family
AAAAPHLE_01784 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AAAAPHLE_01785 1.2e-100 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
AAAAPHLE_01786 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
AAAAPHLE_01787 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AAAAPHLE_01788 1.6e-205 ftsW D Belongs to the SEDS family
AAAAPHLE_01789 1.1e-271
AAAAPHLE_01790 5.1e-259 ica2 GT2 M Glycosyl transferase family group 2
AAAAPHLE_01791 1.2e-103
AAAAPHLE_01792 9.1e-197
AAAAPHLE_01793 0.0 typA T GTP-binding protein TypA
AAAAPHLE_01794 6.3e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
AAAAPHLE_01795 3.3e-46 yktA S Belongs to the UPF0223 family
AAAAPHLE_01796 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
AAAAPHLE_01797 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
AAAAPHLE_01798 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AAAAPHLE_01799 4.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
AAAAPHLE_01800 6.8e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
AAAAPHLE_01801 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AAAAPHLE_01802 1.6e-85
AAAAPHLE_01803 3.1e-33 ykzG S Belongs to the UPF0356 family
AAAAPHLE_01804 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AAAAPHLE_01805 1.7e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
AAAAPHLE_01806 1.7e-28
AAAAPHLE_01807 4.1e-108 mltD CBM50 M NlpC P60 family protein
AAAAPHLE_01808 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AAAAPHLE_01809 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AAAAPHLE_01810 1.6e-120 S Repeat protein
AAAAPHLE_01811 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
AAAAPHLE_01812 3.1e-262 N domain, Protein
AAAAPHLE_01813 6.4e-193 S Bacterial protein of unknown function (DUF916)
AAAAPHLE_01814 2.3e-120 N WxL domain surface cell wall-binding
AAAAPHLE_01815 2.6e-115 ktrA P domain protein
AAAAPHLE_01816 1.3e-241 ktrB P Potassium uptake protein
AAAAPHLE_01817 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AAAAPHLE_01818 4.9e-57 XK27_04120 S Putative amino acid metabolism
AAAAPHLE_01819 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
AAAAPHLE_01820 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AAAAPHLE_01821 4.6e-28
AAAAPHLE_01822 5.6e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
AAAAPHLE_01823 5.4e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AAAAPHLE_01824 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AAAAPHLE_01825 1.2e-86 divIVA D DivIVA domain protein
AAAAPHLE_01826 3.4e-146 ylmH S S4 domain protein
AAAAPHLE_01827 1.2e-36 yggT S YGGT family
AAAAPHLE_01828 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AAAAPHLE_01829 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AAAAPHLE_01830 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AAAAPHLE_01831 1.7e-162 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AAAAPHLE_01832 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AAAAPHLE_01833 1.4e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AAAAPHLE_01834 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AAAAPHLE_01835 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
AAAAPHLE_01836 7.5e-54 ftsL D Cell division protein FtsL
AAAAPHLE_01837 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AAAAPHLE_01838 1.9e-77 mraZ K Belongs to the MraZ family
AAAAPHLE_01839 1.9e-62 S Protein of unknown function (DUF3397)
AAAAPHLE_01840 1.2e-174 corA P CorA-like Mg2+ transporter protein
AAAAPHLE_01841 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
AAAAPHLE_01842 1.4e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AAAAPHLE_01843 5.3e-113 ywnB S NAD(P)H-binding
AAAAPHLE_01844 9.8e-210 brnQ U Component of the transport system for branched-chain amino acids
AAAAPHLE_01846 2.4e-161 rrmA 2.1.1.187 H Methyltransferase
AAAAPHLE_01847 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AAAAPHLE_01848 9.6e-206 XK27_05220 S AI-2E family transporter
AAAAPHLE_01849 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AAAAPHLE_01850 2.8e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
AAAAPHLE_01851 5.1e-116 cutC P Participates in the control of copper homeostasis
AAAAPHLE_01852 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
AAAAPHLE_01853 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AAAAPHLE_01854 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
AAAAPHLE_01855 3.6e-114 yjbH Q Thioredoxin
AAAAPHLE_01856 0.0 pepF E oligoendopeptidase F
AAAAPHLE_01857 7.6e-205 coiA 3.6.4.12 S Competence protein
AAAAPHLE_01858 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AAAAPHLE_01859 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AAAAPHLE_01860 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
AAAAPHLE_01861 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
AAAAPHLE_01871 5.5e-08
AAAAPHLE_01876 1e-63
AAAAPHLE_01877 1.6e-75 yugI 5.3.1.9 J general stress protein
AAAAPHLE_01878 9.4e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AAAAPHLE_01879 3e-119 dedA S SNARE-like domain protein
AAAAPHLE_01880 4.6e-117 S Protein of unknown function (DUF1461)
AAAAPHLE_01881 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AAAAPHLE_01882 1.5e-80 yutD S Protein of unknown function (DUF1027)
AAAAPHLE_01883 3.9e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
AAAAPHLE_01884 1.8e-115 S Calcineurin-like phosphoesterase
AAAAPHLE_01885 1.2e-252 cycA E Amino acid permease
AAAAPHLE_01886 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AAAAPHLE_01887 4.2e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
AAAAPHLE_01889 6.5e-87 S Prokaryotic N-terminal methylation motif
AAAAPHLE_01890 8.6e-20
AAAAPHLE_01891 7.9e-82 gspG NU general secretion pathway protein
AAAAPHLE_01892 5.5e-43 comGC U competence protein ComGC
AAAAPHLE_01893 1.9e-189 comGB NU type II secretion system
AAAAPHLE_01894 2.1e-174 comGA NU Type II IV secretion system protein
AAAAPHLE_01895 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAAAPHLE_01896 8.3e-131 yebC K Transcriptional regulatory protein
AAAAPHLE_01897 1.7e-48 S DsrE/DsrF-like family
AAAAPHLE_01898 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
AAAAPHLE_01899 1.9e-181 ccpA K catabolite control protein A
AAAAPHLE_01900 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AAAAPHLE_01901 1.1e-80 K helix_turn_helix, mercury resistance
AAAAPHLE_01902 2.8e-56
AAAAPHLE_01903 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AAAAPHLE_01904 2.6e-158 ykuT M mechanosensitive ion channel
AAAAPHLE_01905 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AAAAPHLE_01906 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AAAAPHLE_01907 6.5e-87 ykuL S (CBS) domain
AAAAPHLE_01908 1.7e-93 S Phosphoesterase
AAAAPHLE_01909 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AAAAPHLE_01910 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AAAAPHLE_01911 1.9e-92 yslB S Protein of unknown function (DUF2507)
AAAAPHLE_01912 3.3e-52 trxA O Belongs to the thioredoxin family
AAAAPHLE_01913 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AAAAPHLE_01914 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AAAAPHLE_01915 1.6e-48 yrzB S Belongs to the UPF0473 family
AAAAPHLE_01916 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AAAAPHLE_01917 2.4e-43 yrzL S Belongs to the UPF0297 family
AAAAPHLE_01918 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AAAAPHLE_01919 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AAAAPHLE_01920 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
AAAAPHLE_01921 2.6e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AAAAPHLE_01922 2.8e-29 yajC U Preprotein translocase
AAAAPHLE_01923 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AAAAPHLE_01924 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AAAAPHLE_01925 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AAAAPHLE_01926 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AAAAPHLE_01927 3.2e-92
AAAAPHLE_01928 0.0 S Bacterial membrane protein YfhO
AAAAPHLE_01929 1.3e-72
AAAAPHLE_01930 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AAAAPHLE_01931 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AAAAPHLE_01932 2.7e-154 ymdB S YmdB-like protein
AAAAPHLE_01933 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
AAAAPHLE_01934 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AAAAPHLE_01935 9.4e-231 cinA 3.5.1.42 S Belongs to the CinA family
AAAAPHLE_01936 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AAAAPHLE_01937 2e-110 ymfM S Helix-turn-helix domain
AAAAPHLE_01938 2.9e-251 ymfH S Peptidase M16
AAAAPHLE_01939 3.2e-231 ymfF S Peptidase M16 inactive domain protein
AAAAPHLE_01940 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
AAAAPHLE_01941 1.5e-155 aatB ET ABC transporter substrate-binding protein
AAAAPHLE_01942 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AAAAPHLE_01943 4.6e-109 glnP P ABC transporter permease
AAAAPHLE_01944 1.2e-146 minD D Belongs to the ParA family
AAAAPHLE_01945 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
AAAAPHLE_01946 1.6e-88 mreD M rod shape-determining protein MreD
AAAAPHLE_01947 2.6e-144 mreC M Involved in formation and maintenance of cell shape
AAAAPHLE_01948 2.8e-161 mreB D cell shape determining protein MreB
AAAAPHLE_01949 1.3e-116 radC L DNA repair protein
AAAAPHLE_01950 4.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AAAAPHLE_01951 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AAAAPHLE_01952 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AAAAPHLE_01953 7.5e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
AAAAPHLE_01954 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AAAAPHLE_01955 1.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
AAAAPHLE_01956 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AAAAPHLE_01957 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
AAAAPHLE_01958 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AAAAPHLE_01959 6.7e-113 yktB S Belongs to the UPF0637 family
AAAAPHLE_01960 2.5e-80 yueI S Protein of unknown function (DUF1694)
AAAAPHLE_01961 7e-110 S Protein of unknown function (DUF1648)
AAAAPHLE_01962 6.6e-44 czrA K Helix-turn-helix domain
AAAAPHLE_01963 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
AAAAPHLE_01964 8e-238 rarA L recombination factor protein RarA
AAAAPHLE_01965 1.5e-38
AAAAPHLE_01966 6.2e-82 usp6 T universal stress protein
AAAAPHLE_01967 2e-200 bla2 3.5.2.6 V Beta-lactamase enzyme family
AAAAPHLE_01968 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
AAAAPHLE_01969 1.5e-294 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
AAAAPHLE_01970 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AAAAPHLE_01971 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
AAAAPHLE_01972 1.6e-177 S Protein of unknown function (DUF2785)
AAAAPHLE_01973 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
AAAAPHLE_01974 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
AAAAPHLE_01975 1.4e-111 metI U ABC transporter permease
AAAAPHLE_01976 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AAAAPHLE_01977 3.6e-48 gcsH2 E glycine cleavage
AAAAPHLE_01978 9.3e-220 rodA D Belongs to the SEDS family
AAAAPHLE_01979 3.3e-33 S Protein of unknown function (DUF2969)
AAAAPHLE_01980 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AAAAPHLE_01981 2.7e-180 mbl D Cell shape determining protein MreB Mrl
AAAAPHLE_01982 2.1e-102 J Acetyltransferase (GNAT) domain
AAAAPHLE_01983 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAAAPHLE_01984 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AAAAPHLE_01985 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AAAAPHLE_01986 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AAAAPHLE_01987 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AAAAPHLE_01988 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAAAPHLE_01989 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AAAAPHLE_01990 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAAAPHLE_01991 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
AAAAPHLE_01992 5e-232 pyrP F Permease
AAAAPHLE_01993 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AAAAPHLE_01994 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AAAAPHLE_01995 1.3e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AAAAPHLE_01996 8.6e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AAAAPHLE_01997 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AAAAPHLE_01998 9.3e-109 tdk 2.7.1.21 F thymidine kinase
AAAAPHLE_01999 5.8e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
AAAAPHLE_02000 4.2e-135 cobQ S glutamine amidotransferase
AAAAPHLE_02001 9.8e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
AAAAPHLE_02002 4.1e-192 ampC V Beta-lactamase
AAAAPHLE_02003 1.2e-28
AAAAPHLE_02004 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
AAAAPHLE_02005 1.9e-58
AAAAPHLE_02006 2.8e-126
AAAAPHLE_02007 0.0 yfiC V ABC transporter
AAAAPHLE_02008 0.0 ycfI V ABC transporter, ATP-binding protein
AAAAPHLE_02009 1.2e-64 S Protein of unknown function (DUF1093)
AAAAPHLE_02010 3.8e-135 yxkH G Polysaccharide deacetylase
AAAAPHLE_02011 3.4e-35 V Abi-like protein
AAAAPHLE_02013 1.8e-09
AAAAPHLE_02020 1.5e-20
AAAAPHLE_02021 7.3e-219 int L Belongs to the 'phage' integrase family
AAAAPHLE_02023 3.4e-29
AAAAPHLE_02025 2e-38
AAAAPHLE_02026 7.1e-43
AAAAPHLE_02027 7.3e-83 K MarR family
AAAAPHLE_02028 0.0 bztC D nuclear chromosome segregation
AAAAPHLE_02029 0.0 M MucBP domain
AAAAPHLE_02030 2.7e-16
AAAAPHLE_02031 7.2e-17
AAAAPHLE_02032 1.6e-16
AAAAPHLE_02033 1.6e-16
AAAAPHLE_02034 1.9e-18
AAAAPHLE_02035 1.6e-16
AAAAPHLE_02036 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
AAAAPHLE_02037 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
AAAAPHLE_02038 0.0 macB3 V ABC transporter, ATP-binding protein
AAAAPHLE_02039 6.8e-24
AAAAPHLE_02040 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
AAAAPHLE_02041 9.7e-155 glcU U sugar transport
AAAAPHLE_02042 3.2e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
AAAAPHLE_02043 1.1e-286 yclK 2.7.13.3 T Histidine kinase
AAAAPHLE_02044 1.6e-134 K response regulator
AAAAPHLE_02045 3e-243 XK27_08635 S UPF0210 protein
AAAAPHLE_02046 2.3e-38 gcvR T Belongs to the UPF0237 family
AAAAPHLE_02047 1.5e-169 EG EamA-like transporter family
AAAAPHLE_02049 7.7e-92 S ECF-type riboflavin transporter, S component
AAAAPHLE_02050 8.6e-48
AAAAPHLE_02051 9.8e-214 yceI EGP Major facilitator Superfamily
AAAAPHLE_02052 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
AAAAPHLE_02053 3.8e-23
AAAAPHLE_02055 5.9e-160 S Alpha/beta hydrolase of unknown function (DUF915)
AAAAPHLE_02056 4.1e-172 ykfC 3.4.14.13 M NlpC/P60 family
AAAAPHLE_02057 8.6e-81 K AsnC family
AAAAPHLE_02058 2e-35
AAAAPHLE_02059 5.1e-34
AAAAPHLE_02060 1.9e-217 2.7.7.65 T diguanylate cyclase
AAAAPHLE_02061 3.9e-295 S ABC transporter, ATP-binding protein
AAAAPHLE_02062 2e-106 3.2.2.20 K acetyltransferase
AAAAPHLE_02063 5.8e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AAAAPHLE_02064 2.7e-39
AAAAPHLE_02065 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
AAAAPHLE_02066 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AAAAPHLE_02067 9.5e-161 degV S Uncharacterised protein, DegV family COG1307
AAAAPHLE_02068 1.5e-231 hom1 1.1.1.3 E Homoserine dehydrogenase
AAAAPHLE_02069 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
AAAAPHLE_02070 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
AAAAPHLE_02071 1.7e-174 XK27_08835 S ABC transporter
AAAAPHLE_02072 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
AAAAPHLE_02073 2.6e-138 XK27_08845 S ABC transporter, ATP-binding protein
AAAAPHLE_02074 2.8e-257 npr 1.11.1.1 C NADH oxidase
AAAAPHLE_02075 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
AAAAPHLE_02076 4.8e-137 terC P membrane
AAAAPHLE_02077 2.4e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
AAAAPHLE_02078 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAAAPHLE_02079 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
AAAAPHLE_02080 1.9e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AAAAPHLE_02081 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AAAAPHLE_02082 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AAAAPHLE_02083 1.8e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AAAAPHLE_02084 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
AAAAPHLE_02085 1.2e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AAAAPHLE_02086 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AAAAPHLE_02087 8.6e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AAAAPHLE_02088 2.9e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
AAAAPHLE_02089 9.6e-214 ysaA V RDD family
AAAAPHLE_02090 7.6e-166 corA P CorA-like Mg2+ transporter protein
AAAAPHLE_02091 3.4e-50 S Domain of unknown function (DU1801)
AAAAPHLE_02092 3.5e-13 rmeB K transcriptional regulator, MerR family
AAAAPHLE_02093 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AAAAPHLE_02094 2.6e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AAAAPHLE_02095 3.7e-34
AAAAPHLE_02096 3.2e-112 S Protein of unknown function (DUF1211)
AAAAPHLE_02097 0.0 ydgH S MMPL family
AAAAPHLE_02098 6.2e-288 M domain protein
AAAAPHLE_02099 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
AAAAPHLE_02100 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AAAAPHLE_02101 0.0 glpQ 3.1.4.46 C phosphodiesterase
AAAAPHLE_02102 2.6e-183 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
AAAAPHLE_02103 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
AAAAPHLE_02104 6.2e-182 3.6.4.13 S domain, Protein
AAAAPHLE_02105 6.7e-167 S Polyphosphate kinase 2 (PPK2)
AAAAPHLE_02106 2.5e-98 drgA C Nitroreductase family
AAAAPHLE_02107 2.7e-177 iunH2 3.2.2.1 F nucleoside hydrolase
AAAAPHLE_02108 1.7e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AAAAPHLE_02109 1.4e-104 glcU U sugar transport
AAAAPHLE_02110 6.2e-165 bglK_1 GK ROK family
AAAAPHLE_02111 5.3e-155 pflC 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AAAAPHLE_02112 3.7e-134 yciT K DeoR C terminal sensor domain
AAAAPHLE_02113 0.0 ybiW 2.3.1.54 C Pyruvate formate lyase-like
AAAAPHLE_02114 1.8e-178 K sugar-binding domain protein
AAAAPHLE_02115 1.5e-124 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
AAAAPHLE_02116 4.2e-141 S Sucrose-6F-phosphate phosphohydrolase
AAAAPHLE_02117 6.4e-176 ccpB 5.1.1.1 K lacI family
AAAAPHLE_02118 3.6e-157 K Helix-turn-helix domain, rpiR family
AAAAPHLE_02119 2.7e-177 S Oxidoreductase family, NAD-binding Rossmann fold
AAAAPHLE_02120 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
AAAAPHLE_02121 0.0 yjcE P Sodium proton antiporter
AAAAPHLE_02122 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AAAAPHLE_02123 3.7e-107 pncA Q Isochorismatase family
AAAAPHLE_02124 2.7e-132
AAAAPHLE_02125 5.1e-125 skfE V ABC transporter
AAAAPHLE_02126 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
AAAAPHLE_02127 1.6e-26 S Enterocin A Immunity
AAAAPHLE_02128 2e-174 D Alpha beta
AAAAPHLE_02129 0.0 pepF2 E Oligopeptidase F
AAAAPHLE_02130 1.3e-72 K Transcriptional regulator
AAAAPHLE_02131 2.3e-164
AAAAPHLE_02132 6e-58
AAAAPHLE_02133 5.5e-46
AAAAPHLE_02134 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AAAAPHLE_02135 6.4e-69
AAAAPHLE_02136 2.4e-144 yjfP S Dienelactone hydrolase family
AAAAPHLE_02137 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
AAAAPHLE_02138 3.9e-204 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
AAAAPHLE_02139 5.2e-47
AAAAPHLE_02140 6.3e-45
AAAAPHLE_02141 5e-82 yybC S Protein of unknown function (DUF2798)
AAAAPHLE_02142 1.7e-73
AAAAPHLE_02143 4e-60
AAAAPHLE_02144 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
AAAAPHLE_02145 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
AAAAPHLE_02146 3e-72 G PTS system fructose IIA component
AAAAPHLE_02147 3.2e-147 G PTS system mannose/fructose/sorbose family IID component
AAAAPHLE_02148 4.7e-143 agaC G PTS system sorbose-specific iic component
AAAAPHLE_02149 4.6e-85 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
AAAAPHLE_02150 2e-129 K UTRA domain
AAAAPHLE_02151 1.6e-79 uspA T universal stress protein
AAAAPHLE_02152 1.6e-155 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AAAAPHLE_02153 1.7e-48 K Cro/C1-type HTH DNA-binding domain
AAAAPHLE_02154 3.3e-21 S Protein of unknown function (DUF2929)
AAAAPHLE_02155 9.4e-225 lsgC M Glycosyl transferases group 1
AAAAPHLE_02156 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
AAAAPHLE_02157 2.3e-164 S Putative esterase
AAAAPHLE_02158 2.4e-130 gntR2 K Transcriptional regulator
AAAAPHLE_02159 9.9e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AAAAPHLE_02160 6.8e-139
AAAAPHLE_02161 1.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
AAAAPHLE_02162 5.5e-138 rrp8 K LytTr DNA-binding domain
AAAAPHLE_02163 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
AAAAPHLE_02164 7.7e-61
AAAAPHLE_02165 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
AAAAPHLE_02166 4.4e-58
AAAAPHLE_02167 1.2e-239 yhdP S Transporter associated domain
AAAAPHLE_02168 4.9e-87 nrdI F Belongs to the NrdI family
AAAAPHLE_02169 2.9e-269 yjcE P Sodium proton antiporter
AAAAPHLE_02170 5.7e-206 yttB EGP Major facilitator Superfamily
AAAAPHLE_02171 7.3e-62 K helix_turn_helix, mercury resistance
AAAAPHLE_02172 3.1e-65 C Zinc-binding dehydrogenase
AAAAPHLE_02173 2.5e-56 S SdpI/YhfL protein family
AAAAPHLE_02174 2.4e-294 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AAAAPHLE_02175 7.2e-261 gabR K Bacterial regulatory proteins, gntR family
AAAAPHLE_02176 4.1e-57 patA 2.6.1.1 E Aminotransferase
AAAAPHLE_02177 5.2e-110 patA 2.6.1.1 E Aminotransferase
AAAAPHLE_02178 5.1e-159 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAAAPHLE_02179 8.7e-18
AAAAPHLE_02180 1.7e-126 S membrane transporter protein
AAAAPHLE_02181 1.9e-161 mleR K LysR family
AAAAPHLE_02182 5.6e-115 ylbE GM NAD(P)H-binding
AAAAPHLE_02183 8.2e-96 wecD K Acetyltransferase (GNAT) family
AAAAPHLE_02184 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AAAAPHLE_02185 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
AAAAPHLE_02186 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
AAAAPHLE_02187 6.2e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AAAAPHLE_02188 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AAAAPHLE_02189 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AAAAPHLE_02190 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AAAAPHLE_02191 1.2e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AAAAPHLE_02192 9.9e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AAAAPHLE_02193 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AAAAPHLE_02194 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AAAAPHLE_02195 1e-298 pucR QT Purine catabolism regulatory protein-like family
AAAAPHLE_02196 2.7e-236 pbuX F xanthine permease
AAAAPHLE_02197 2.4e-221 pbuG S Permease family
AAAAPHLE_02198 5.6e-161 GM NmrA-like family
AAAAPHLE_02199 7.2e-155 T EAL domain
AAAAPHLE_02200 2.6e-94
AAAAPHLE_02201 2.7e-252 pgaC GT2 M Glycosyl transferase
AAAAPHLE_02202 8.7e-98 2.1.1.14 E Methionine synthase
AAAAPHLE_02203 2.8e-14 2.1.1.14 E Methionine synthase
AAAAPHLE_02204 9.3e-215 purD 6.3.4.13 F Belongs to the GARS family
AAAAPHLE_02205 5.9e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AAAAPHLE_02206 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AAAAPHLE_02207 7.2e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AAAAPHLE_02208 1.1e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AAAAPHLE_02209 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AAAAPHLE_02210 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AAAAPHLE_02211 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AAAAPHLE_02212 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AAAAPHLE_02213 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AAAAPHLE_02214 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AAAAPHLE_02215 1.5e-223 XK27_09615 1.3.5.4 S reductase
AAAAPHLE_02216 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
AAAAPHLE_02217 1.3e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
AAAAPHLE_02218 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
AAAAPHLE_02219 9.2e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
AAAAPHLE_02220 7.5e-149 S Alpha/beta hydrolase of unknown function (DUF915)
AAAAPHLE_02221 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
AAAAPHLE_02222 8.6e-139 cysA V ABC transporter, ATP-binding protein
AAAAPHLE_02223 0.0 V FtsX-like permease family
AAAAPHLE_02224 8e-42
AAAAPHLE_02225 7.9e-61 gntR1 K Transcriptional regulator, GntR family
AAAAPHLE_02226 6.7e-151 V ABC transporter, ATP-binding protein
AAAAPHLE_02227 5.8e-149
AAAAPHLE_02228 6.7e-81 uspA T universal stress protein
AAAAPHLE_02229 3.6e-35
AAAAPHLE_02230 5.5e-71 gtcA S Teichoic acid glycosylation protein
AAAAPHLE_02232 5.6e-233 malY 4.4.1.8 E Aminotransferase, class I
AAAAPHLE_02233 2.1e-85 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
AAAAPHLE_02234 2.1e-117
AAAAPHLE_02235 1.5e-52
AAAAPHLE_02237 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
AAAAPHLE_02238 3.6e-282 thrC 4.2.3.1 E Threonine synthase
AAAAPHLE_02239 5e-145 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
AAAAPHLE_02240 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
AAAAPHLE_02241 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
AAAAPHLE_02242 1.1e-101 3.6.1.13 L Belongs to the Nudix hydrolase family
AAAAPHLE_02243 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
AAAAPHLE_02244 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
AAAAPHLE_02245 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
AAAAPHLE_02246 4.2e-211 S Bacterial protein of unknown function (DUF871)
AAAAPHLE_02247 2.1e-232 S Sterol carrier protein domain
AAAAPHLE_02248 2.7e-225 EGP Major facilitator Superfamily
AAAAPHLE_02249 3.6e-88 niaR S 3H domain
AAAAPHLE_02250 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AAAAPHLE_02251 2.8e-117 K Transcriptional regulator
AAAAPHLE_02252 9.2e-154 V ABC transporter
AAAAPHLE_02253 4.5e-132 V AAA domain, putative AbiEii toxin, Type IV TA system
AAAAPHLE_02254 3.7e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
AAAAPHLE_02255 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_02256 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_02257 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
AAAAPHLE_02258 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
AAAAPHLE_02259 1.8e-130 gntR K UTRA
AAAAPHLE_02260 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
AAAAPHLE_02261 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
AAAAPHLE_02262 1.8e-81
AAAAPHLE_02263 9.8e-152 S hydrolase
AAAAPHLE_02264 6.5e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AAAAPHLE_02265 8.3e-152 EG EamA-like transporter family
AAAAPHLE_02266 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
AAAAPHLE_02267 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
AAAAPHLE_02268 1e-232
AAAAPHLE_02269 9.4e-77 fld C Flavodoxin
AAAAPHLE_02270 0.0 M Bacterial Ig-like domain (group 3)
AAAAPHLE_02271 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
AAAAPHLE_02272 2.7e-32
AAAAPHLE_02273 3.1e-128 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
AAAAPHLE_02274 2.2e-268 ycaM E amino acid
AAAAPHLE_02275 1.1e-77 K Winged helix DNA-binding domain
AAAAPHLE_02276 5.6e-166 S Oxidoreductase, aldo keto reductase family protein
AAAAPHLE_02277 5.7e-163 akr5f 1.1.1.346 S reductase
AAAAPHLE_02278 4.6e-163 K Transcriptional regulator
AAAAPHLE_02280 1.8e-84 hmpT S Pfam:DUF3816
AAAAPHLE_02281 1.7e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AAAAPHLE_02282 1.1e-110
AAAAPHLE_02283 6.2e-153 M Glycosyl hydrolases family 25
AAAAPHLE_02284 2e-143 yvpB S Peptidase_C39 like family
AAAAPHLE_02285 4e-92 yueI S Protein of unknown function (DUF1694)
AAAAPHLE_02286 1.6e-115 S Protein of unknown function (DUF554)
AAAAPHLE_02287 1.9e-147 KT helix_turn_helix, mercury resistance
AAAAPHLE_02288 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AAAAPHLE_02289 6.6e-95 S Protein of unknown function (DUF1440)
AAAAPHLE_02290 5.2e-174 hrtB V ABC transporter permease
AAAAPHLE_02291 4.7e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
AAAAPHLE_02292 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
AAAAPHLE_02293 1.8e-184 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
AAAAPHLE_02294 8.1e-99 1.5.1.3 H RibD C-terminal domain
AAAAPHLE_02295 4.1e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AAAAPHLE_02296 7.5e-110 S Membrane
AAAAPHLE_02297 1.2e-155 mleP3 S Membrane transport protein
AAAAPHLE_02298 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
AAAAPHLE_02299 7.6e-190 ynfM EGP Major facilitator Superfamily
AAAAPHLE_02300 2.8e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AAAAPHLE_02301 1.1e-270 lmrB EGP Major facilitator Superfamily
AAAAPHLE_02302 2e-75 S Domain of unknown function (DUF4811)
AAAAPHLE_02303 1.8e-101 rimL J Acetyltransferase (GNAT) domain
AAAAPHLE_02304 9.3e-173 S Conserved hypothetical protein 698
AAAAPHLE_02305 3.7e-151 rlrG K Transcriptional regulator
AAAAPHLE_02306 2.4e-297 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
AAAAPHLE_02307 1.8e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
AAAAPHLE_02309 5.6e-51 lytE M LysM domain
AAAAPHLE_02310 1.2e-91 ogt 2.1.1.63 L Methyltransferase
AAAAPHLE_02312 2e-166 natA S ABC transporter, ATP-binding protein
AAAAPHLE_02313 4.7e-211 natB CP ABC-2 family transporter protein
AAAAPHLE_02314 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AAAAPHLE_02315 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
AAAAPHLE_02316 3.2e-76 yphH S Cupin domain
AAAAPHLE_02317 9.8e-79 K transcriptional regulator, MerR family
AAAAPHLE_02318 1.1e-234 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
AAAAPHLE_02319 0.0 ylbB V ABC transporter permease
AAAAPHLE_02320 1.9e-119 macB V ABC transporter, ATP-binding protein
AAAAPHLE_02322 3e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AAAAPHLE_02323 1.3e-21 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
AAAAPHLE_02324 7.7e-43 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
AAAAPHLE_02325 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AAAAPHLE_02326 2.2e-111 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AAAAPHLE_02327 1.3e-84
AAAAPHLE_02328 9.2e-59 yvbK 3.1.3.25 K GNAT family
AAAAPHLE_02329 1e-13 yvbK 3.1.3.25 K GNAT family
AAAAPHLE_02330 3.2e-37
AAAAPHLE_02331 8.2e-48
AAAAPHLE_02332 3.8e-111 pgm8 G Histidine phosphatase superfamily (branch 1)
AAAAPHLE_02333 8.4e-60 S Domain of unknown function (DUF4440)
AAAAPHLE_02334 2.6e-155 K LysR substrate binding domain
AAAAPHLE_02335 5.4e-104 GM NAD(P)H-binding
AAAAPHLE_02336 1.5e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
AAAAPHLE_02337 2.3e-148 IQ Enoyl-(Acyl carrier protein) reductase
AAAAPHLE_02338 1.3e-34
AAAAPHLE_02339 6.1e-76 T Belongs to the universal stress protein A family
AAAAPHLE_02340 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
AAAAPHLE_02341 2.2e-125 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AAAAPHLE_02342 2.1e-31
AAAAPHLE_02343 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
AAAAPHLE_02344 3.1e-220 patB 4.4.1.8 E Aminotransferase, class I
AAAAPHLE_02345 7.4e-102 M Protein of unknown function (DUF3737)
AAAAPHLE_02346 4.1e-164 C Aldo/keto reductase family
AAAAPHLE_02347 4.3e-22 C Aldo/keto reductase family
AAAAPHLE_02349 0.0 mdlB V ABC transporter
AAAAPHLE_02350 0.0 mdlA V ABC transporter
AAAAPHLE_02351 1.3e-246 EGP Major facilitator Superfamily
AAAAPHLE_02354 3.6e-09
AAAAPHLE_02355 2e-192 yhgE V domain protein
AAAAPHLE_02356 5.1e-96 K Transcriptional regulator (TetR family)
AAAAPHLE_02357 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
AAAAPHLE_02358 1e-136 endA F DNA RNA non-specific endonuclease
AAAAPHLE_02359 6.3e-99 speG J Acetyltransferase (GNAT) domain
AAAAPHLE_02360 3.7e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
AAAAPHLE_02361 1e-132 2.7.1.89 M Phosphotransferase enzyme family
AAAAPHLE_02362 4.5e-222 S CAAX protease self-immunity
AAAAPHLE_02363 9.3e-308 ybiT S ABC transporter, ATP-binding protein
AAAAPHLE_02364 3.4e-146 3.1.3.102, 3.1.3.104 S hydrolase
AAAAPHLE_02365 0.0 S Predicted membrane protein (DUF2207)
AAAAPHLE_02366 0.0 uvrA3 L excinuclease ABC
AAAAPHLE_02367 1.7e-208 EGP Major facilitator Superfamily
AAAAPHLE_02368 2.9e-173 ropB K Helix-turn-helix XRE-family like proteins
AAAAPHLE_02369 3e-175 pepR1 3.4.11.5 I Releases the N-terminal proline from various substrates
AAAAPHLE_02370 9.8e-250 puuP_1 E Amino acid permease
AAAAPHLE_02371 1.7e-233 yxiO S Vacuole effluxer Atg22 like
AAAAPHLE_02372 6.6e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
AAAAPHLE_02373 2e-160 I alpha/beta hydrolase fold
AAAAPHLE_02374 2.6e-129 treR K UTRA
AAAAPHLE_02375 1.5e-234
AAAAPHLE_02376 8.3e-15
AAAAPHLE_02377 5.6e-39 S Cytochrome B5
AAAAPHLE_02378 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AAAAPHLE_02379 6.2e-218 2.7.7.65 T Diguanylate cyclase, GGDEF domain
AAAAPHLE_02380 1.2e-126 yliE T EAL domain
AAAAPHLE_02381 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AAAAPHLE_02382 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AAAAPHLE_02383 2e-80
AAAAPHLE_02384 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
AAAAPHLE_02385 1.3e-190 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AAAAPHLE_02386 7.6e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AAAAPHLE_02387 8.3e-22
AAAAPHLE_02388 4.5e-40
AAAAPHLE_02389 9.9e-42
AAAAPHLE_02390 1.2e-163 K LysR substrate binding domain
AAAAPHLE_02391 2.4e-243 P Sodium:sulfate symporter transmembrane region
AAAAPHLE_02392 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AAAAPHLE_02393 7.4e-264 S response to antibiotic
AAAAPHLE_02394 8.2e-134 S zinc-ribbon domain
AAAAPHLE_02396 3.2e-37
AAAAPHLE_02397 2.4e-133 aroD S Alpha/beta hydrolase family
AAAAPHLE_02398 2.2e-175 S Phosphotransferase system, EIIC
AAAAPHLE_02399 2.5e-269 I acetylesterase activity
AAAAPHLE_02400 6.4e-224 sdrF M Collagen binding domain
AAAAPHLE_02401 1.8e-159 yicL EG EamA-like transporter family
AAAAPHLE_02402 1.1e-127 E lipolytic protein G-D-S-L family
AAAAPHLE_02403 2e-177 4.1.1.52 S Amidohydrolase
AAAAPHLE_02404 6.7e-113 K Transcriptional regulator C-terminal region
AAAAPHLE_02405 1.4e-47 3.6.4.12 K HxlR-like helix-turn-helix
AAAAPHLE_02406 3.8e-162 ypbG 2.7.1.2 GK ROK family
AAAAPHLE_02407 0.0 lmrA 3.6.3.44 V ABC transporter
AAAAPHLE_02408 1.1e-95 rmaB K Transcriptional regulator, MarR family
AAAAPHLE_02409 1.3e-119 drgA C Nitroreductase family
AAAAPHLE_02410 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
AAAAPHLE_02411 2.9e-117 cmpC S ATPases associated with a variety of cellular activities
AAAAPHLE_02412 8.7e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
AAAAPHLE_02413 2.3e-168 XK27_00670 S ABC transporter
AAAAPHLE_02414 1e-260
AAAAPHLE_02415 7.3e-62
AAAAPHLE_02416 5.1e-190 S Cell surface protein
AAAAPHLE_02417 1e-91 S WxL domain surface cell wall-binding
AAAAPHLE_02418 2e-96 acuB S Domain in cystathionine beta-synthase and other proteins.
AAAAPHLE_02419 3.3e-124 livF E ABC transporter
AAAAPHLE_02420 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
AAAAPHLE_02421 1.5e-140 livM E Branched-chain amino acid transport system / permease component
AAAAPHLE_02422 6.5e-154 livH U Branched-chain amino acid transport system / permease component
AAAAPHLE_02423 1.2e-211 livJ E Receptor family ligand binding region
AAAAPHLE_02425 7e-33
AAAAPHLE_02426 3.5e-114 zmp3 O Zinc-dependent metalloprotease
AAAAPHLE_02427 2.8e-82 gtrA S GtrA-like protein
AAAAPHLE_02428 2.2e-122 K Helix-turn-helix XRE-family like proteins
AAAAPHLE_02429 1.2e-283 mntH P H( )-stimulated, divalent metal cation uptake system
AAAAPHLE_02430 6.8e-72 T Belongs to the universal stress protein A family
AAAAPHLE_02431 4e-46
AAAAPHLE_02432 9.2e-116 S SNARE associated Golgi protein
AAAAPHLE_02433 1e-48 K Transcriptional regulator, ArsR family
AAAAPHLE_02434 3.4e-95 cadD P Cadmium resistance transporter
AAAAPHLE_02435 0.0 yhcA V ABC transporter, ATP-binding protein
AAAAPHLE_02436 0.0 P Concanavalin A-like lectin/glucanases superfamily
AAAAPHLE_02437 7.4e-64
AAAAPHLE_02438 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
AAAAPHLE_02439 3.2e-55
AAAAPHLE_02440 2e-149 dicA K Helix-turn-helix domain
AAAAPHLE_02441 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AAAAPHLE_02442 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
AAAAPHLE_02443 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_02444 7e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_02445 6.9e-184 1.1.1.219 GM Male sterility protein
AAAAPHLE_02446 5.1e-75 K helix_turn_helix, mercury resistance
AAAAPHLE_02447 8.7e-65 M LysM domain
AAAAPHLE_02448 2.3e-95 M Lysin motif
AAAAPHLE_02449 4e-107 S SdpI/YhfL protein family
AAAAPHLE_02450 1.8e-54 nudA S ASCH
AAAAPHLE_02451 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
AAAAPHLE_02452 1.1e-92
AAAAPHLE_02453 2.1e-82 tag 3.2.2.20 L Methyladenine glycosylase
AAAAPHLE_02454 5.7e-219 T diguanylate cyclase
AAAAPHLE_02455 3e-72 S Psort location Cytoplasmic, score
AAAAPHLE_02456 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
AAAAPHLE_02457 8.6e-218 ykiI
AAAAPHLE_02458 0.0 V ABC transporter
AAAAPHLE_02459 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
AAAAPHLE_02460 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
AAAAPHLE_02461 1.3e-162 IQ KR domain
AAAAPHLE_02463 3.7e-70
AAAAPHLE_02464 1.9e-144 K Helix-turn-helix XRE-family like proteins
AAAAPHLE_02465 9.6e-267 yjeM E Amino Acid
AAAAPHLE_02466 3.9e-66 lysM M LysM domain
AAAAPHLE_02467 6.7e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
AAAAPHLE_02468 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
AAAAPHLE_02469 0.0 ctpA 3.6.3.54 P P-type ATPase
AAAAPHLE_02470 1.7e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AAAAPHLE_02471 7e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AAAAPHLE_02472 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AAAAPHLE_02473 6e-140 K Helix-turn-helix domain
AAAAPHLE_02474 4.2e-37 S TfoX C-terminal domain
AAAAPHLE_02475 7.8e-228 hpk9 2.7.13.3 T GHKL domain
AAAAPHLE_02476 2.2e-263
AAAAPHLE_02477 1.3e-75
AAAAPHLE_02478 2.6e-189 S Cell surface protein
AAAAPHLE_02479 1.7e-101 S WxL domain surface cell wall-binding
AAAAPHLE_02480 1.2e-177 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
AAAAPHLE_02481 3.8e-69 S Iron-sulphur cluster biosynthesis
AAAAPHLE_02482 2.8e-114 S GyrI-like small molecule binding domain
AAAAPHLE_02483 6.2e-188 S Cell surface protein
AAAAPHLE_02484 7.5e-101 S WxL domain surface cell wall-binding
AAAAPHLE_02485 1.1e-62
AAAAPHLE_02486 6.6e-213 NU Mycoplasma protein of unknown function, DUF285
AAAAPHLE_02487 5.9e-117
AAAAPHLE_02488 1.5e-115 S Haloacid dehalogenase-like hydrolase
AAAAPHLE_02489 4.7e-57 K Transcriptional regulator PadR-like family
AAAAPHLE_02490 2.1e-120 M1-1017
AAAAPHLE_02491 2e-61 K Transcriptional regulator, HxlR family
AAAAPHLE_02492 1.6e-211 ytbD EGP Major facilitator Superfamily
AAAAPHLE_02493 1.4e-94 M ErfK YbiS YcfS YnhG
AAAAPHLE_02494 0.0 asnB 6.3.5.4 E Asparagine synthase
AAAAPHLE_02495 5.7e-135 K LytTr DNA-binding domain
AAAAPHLE_02496 2e-204 2.7.13.3 T GHKL domain
AAAAPHLE_02497 7.9e-100 fadR K Bacterial regulatory proteins, tetR family
AAAAPHLE_02498 1.1e-167 GM NmrA-like family
AAAAPHLE_02499 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
AAAAPHLE_02500 0.0 M Glycosyl hydrolases family 25
AAAAPHLE_02501 1e-47 S Domain of unknown function (DUF1905)
AAAAPHLE_02502 2.4e-62 hxlR K HxlR-like helix-turn-helix
AAAAPHLE_02503 9.8e-132 ydfG S KR domain
AAAAPHLE_02504 4.2e-98 K Bacterial regulatory proteins, tetR family
AAAAPHLE_02505 6e-191 1.1.1.219 GM Male sterility protein
AAAAPHLE_02506 5.9e-100 S Protein of unknown function (DUF1211)
AAAAPHLE_02507 4.4e-180 S Aldo keto reductase
AAAAPHLE_02509 7.8e-253 yfjF U Sugar (and other) transporter
AAAAPHLE_02510 7.4e-109 K Bacterial regulatory proteins, tetR family
AAAAPHLE_02511 4.9e-168 fhuD P Periplasmic binding protein
AAAAPHLE_02512 1.1e-144 fhuC 3.6.3.34 HP ABC transporter
AAAAPHLE_02513 2.8e-177 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAAAPHLE_02514 9.5e-170 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAAAPHLE_02515 5.4e-92 K Bacterial regulatory proteins, tetR family
AAAAPHLE_02516 2.1e-157 GM NmrA-like family
AAAAPHLE_02517 2.5e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AAAAPHLE_02518 1.3e-68 maa S transferase hexapeptide repeat
AAAAPHLE_02519 1.2e-146 IQ Enoyl-(Acyl carrier protein) reductase
AAAAPHLE_02520 4e-53 K helix_turn_helix, mercury resistance
AAAAPHLE_02521 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
AAAAPHLE_02522 6.9e-171 S Bacterial protein of unknown function (DUF916)
AAAAPHLE_02523 1.1e-88 S WxL domain surface cell wall-binding
AAAAPHLE_02524 4.6e-188 NU Mycoplasma protein of unknown function, DUF285
AAAAPHLE_02525 4e-116 K Bacterial regulatory proteins, tetR family
AAAAPHLE_02526 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AAAAPHLE_02527 2.3e-290 yjcE P Sodium proton antiporter
AAAAPHLE_02528 3.3e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
AAAAPHLE_02530 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
AAAAPHLE_02532 2.2e-115 K UTRA
AAAAPHLE_02533 1.2e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_02534 1.6e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_02535 4.1e-65
AAAAPHLE_02536 1.5e-11
AAAAPHLE_02537 9.4e-41 4.1.1.44 S Carboxymuconolactone decarboxylase family
AAAAPHLE_02538 2.2e-23 rmeD K helix_turn_helix, mercury resistance
AAAAPHLE_02539 4.9e-63 S Protein of unknown function (DUF1093)
AAAAPHLE_02540 3.6e-206 S Membrane
AAAAPHLE_02541 1e-41 S Protein of unknown function (DUF3781)
AAAAPHLE_02542 1e-95 ydeA S intracellular protease amidase
AAAAPHLE_02543 3e-51 K HxlR-like helix-turn-helix
AAAAPHLE_02544 3.1e-149 C Alcohol dehydrogenase GroES-like domain
AAAAPHLE_02545 5.8e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
AAAAPHLE_02546 2.2e-38
AAAAPHLE_02547 2.5e-22 Q Methyltransferase domain
AAAAPHLE_02548 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AAAAPHLE_02549 1.9e-171 K AI-2E family transporter
AAAAPHLE_02550 2.9e-210 xylR GK ROK family
AAAAPHLE_02551 2.4e-83
AAAAPHLE_02552 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
AAAAPHLE_02553 1.8e-162
AAAAPHLE_02554 6.2e-145 KLT Protein tyrosine kinase
AAAAPHLE_02555 2.3e-28 KLT Protein tyrosine kinase
AAAAPHLE_02556 1.1e-22 S Protein of unknown function (DUF4064)
AAAAPHLE_02557 1.7e-96 S Domain of unknown function (DUF4352)
AAAAPHLE_02558 1.5e-74 S Psort location Cytoplasmic, score
AAAAPHLE_02559 4.1e-54
AAAAPHLE_02560 1.8e-109 S membrane transporter protein
AAAAPHLE_02561 2.3e-54 azlD S branched-chain amino acid
AAAAPHLE_02562 5.1e-131 azlC E branched-chain amino acid
AAAAPHLE_02563 2.9e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
AAAAPHLE_02564 4.2e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AAAAPHLE_02565 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
AAAAPHLE_02566 3.2e-124 K response regulator
AAAAPHLE_02567 5.5e-124 yoaK S Protein of unknown function (DUF1275)
AAAAPHLE_02568 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AAAAPHLE_02569 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AAAAPHLE_02570 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
AAAAPHLE_02571 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AAAAPHLE_02572 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
AAAAPHLE_02573 4.8e-157 spo0J K Belongs to the ParB family
AAAAPHLE_02574 1.8e-136 soj D Sporulation initiation inhibitor
AAAAPHLE_02575 2.7e-149 noc K Belongs to the ParB family
AAAAPHLE_02576 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
AAAAPHLE_02577 4.1e-226 nupG F Nucleoside
AAAAPHLE_02578 5e-161 S Bacterial membrane protein, YfhO
AAAAPHLE_02579 1.5e-147 S Alpha/beta hydrolase of unknown function (DUF915)
AAAAPHLE_02580 2.1e-168 K LysR substrate binding domain
AAAAPHLE_02581 5.5e-236 EK Aminotransferase, class I
AAAAPHLE_02582 5.2e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
AAAAPHLE_02583 8.1e-123 tcyB E ABC transporter
AAAAPHLE_02584 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AAAAPHLE_02585 6.9e-119 tcyA ET Belongs to the bacterial solute-binding protein 3 family
AAAAPHLE_02586 2.2e-78 KT response to antibiotic
AAAAPHLE_02587 1.5e-52 K Transcriptional regulator
AAAAPHLE_02588 1.5e-83 XK27_06920 S Protein of unknown function (DUF1700)
AAAAPHLE_02589 1.8e-125 S Putative adhesin
AAAAPHLE_02590 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
AAAAPHLE_02591 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
AAAAPHLE_02592 3.7e-182 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
AAAAPHLE_02593 1.3e-204 S DUF218 domain
AAAAPHLE_02594 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
AAAAPHLE_02595 1.6e-117 ybbL S ATPases associated with a variety of cellular activities
AAAAPHLE_02596 2.7e-274 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AAAAPHLE_02597 2.7e-76
AAAAPHLE_02598 8.7e-206 4.1.1.45 E amidohydrolase
AAAAPHLE_02599 0.0 2.7.1.193, 2.7.1.211 G phosphotransferase system
AAAAPHLE_02600 6.8e-242 S Neutral/alkaline non-lysosomal ceramidase, N-terminal
AAAAPHLE_02601 3.7e-232
AAAAPHLE_02602 1.5e-163 K LysR substrate binding domain
AAAAPHLE_02603 1.9e-150 qorB 1.6.5.2 GM NmrA-like family
AAAAPHLE_02604 9.4e-147 cof S haloacid dehalogenase-like hydrolase
AAAAPHLE_02605 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
AAAAPHLE_02606 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
AAAAPHLE_02607 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
AAAAPHLE_02608 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
AAAAPHLE_02609 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
AAAAPHLE_02610 2.2e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AAAAPHLE_02611 2e-77 merR K MerR family regulatory protein
AAAAPHLE_02612 2.6e-155 1.6.5.2 GM NmrA-like family
AAAAPHLE_02613 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
AAAAPHLE_02614 2.5e-126 magIII L Base excision DNA repair protein, HhH-GPD family
AAAAPHLE_02615 1.4e-08
AAAAPHLE_02616 2e-100 S NADPH-dependent FMN reductase
AAAAPHLE_02617 2.3e-237 S module of peptide synthetase
AAAAPHLE_02618 2e-106
AAAAPHLE_02619 9.8e-88 perR P Belongs to the Fur family
AAAAPHLE_02620 2.1e-58 S Enterocin A Immunity
AAAAPHLE_02621 5.4e-36 S Phospholipase_D-nuclease N-terminal
AAAAPHLE_02622 5e-167 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
AAAAPHLE_02623 3.8e-104 J Acetyltransferase (GNAT) domain
AAAAPHLE_02624 5.1e-64 lrgA S LrgA family
AAAAPHLE_02625 7.3e-127 lrgB M LrgB-like family
AAAAPHLE_02626 2.5e-145 DegV S EDD domain protein, DegV family
AAAAPHLE_02627 4.1e-25
AAAAPHLE_02628 3.5e-118 yugP S Putative neutral zinc metallopeptidase
AAAAPHLE_02629 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
AAAAPHLE_02630 6.2e-165 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
AAAAPHLE_02631 1.7e-184 D Alpha beta
AAAAPHLE_02632 2.7e-197 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AAAAPHLE_02633 4e-256 gor 1.8.1.7 C Glutathione reductase
AAAAPHLE_02634 3.4e-55 S Enterocin A Immunity
AAAAPHLE_02635 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AAAAPHLE_02636 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AAAAPHLE_02637 3.5e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AAAAPHLE_02638 5.8e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
AAAAPHLE_02639 8.1e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAAAPHLE_02641 1.3e-64 K Bacterial regulatory proteins, tetR family
AAAAPHLE_02642 3e-140 XK27_06930 S ABC-2 family transporter protein
AAAAPHLE_02643 4.3e-83
AAAAPHLE_02644 5.6e-256 yhdG E C-terminus of AA_permease
AAAAPHLE_02646 0.0 kup P Transport of potassium into the cell
AAAAPHLE_02647 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AAAAPHLE_02648 6.9e-179 K AI-2E family transporter
AAAAPHLE_02649 1.2e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
AAAAPHLE_02650 4.4e-59 qacC P Small Multidrug Resistance protein
AAAAPHLE_02651 1.1e-44 qacH U Small Multidrug Resistance protein
AAAAPHLE_02652 3e-116 hly S protein, hemolysin III
AAAAPHLE_02653 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
AAAAPHLE_02654 4.7e-160 czcD P cation diffusion facilitator family transporter
AAAAPHLE_02655 4.3e-101 K Helix-turn-helix XRE-family like proteins
AAAAPHLE_02657 2.1e-21
AAAAPHLE_02658 6.5e-96 tag 3.2.2.20 L glycosylase
AAAAPHLE_02659 6.8e-212 folP 2.5.1.15 H dihydropteroate synthase
AAAAPHLE_02660 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
AAAAPHLE_02661 2.7e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AAAAPHLE_02662 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
AAAAPHLE_02663 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
AAAAPHLE_02664 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AAAAPHLE_02665 4.7e-83 cvpA S Colicin V production protein
AAAAPHLE_02666 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
AAAAPHLE_02667 1.3e-249 EGP Major facilitator Superfamily
AAAAPHLE_02669 7e-40
AAAAPHLE_02670 6.2e-96 V VanZ like family
AAAAPHLE_02671 5e-195 blaA6 V Beta-lactamase
AAAAPHLE_02672 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
AAAAPHLE_02673 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AAAAPHLE_02674 3.3e-52 yitW S Pfam:DUF59
AAAAPHLE_02675 7.7e-174 S Aldo keto reductase
AAAAPHLE_02676 3.3e-97 FG HIT domain
AAAAPHLE_02677 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
AAAAPHLE_02678 1.4e-77
AAAAPHLE_02679 2.4e-121 E GDSL-like Lipase/Acylhydrolase family
AAAAPHLE_02680 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
AAAAPHLE_02681 0.0 cadA P P-type ATPase
AAAAPHLE_02683 4.8e-125 yyaQ S YjbR
AAAAPHLE_02684 1e-218 S Uncharacterized protein conserved in bacteria (DUF2325)
AAAAPHLE_02685 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AAAAPHLE_02686 4.8e-199 frlB M SIS domain
AAAAPHLE_02687 6.1e-27 3.2.2.10 S Belongs to the LOG family
AAAAPHLE_02688 1.2e-253 nhaC C Na H antiporter NhaC
AAAAPHLE_02689 2.6e-250 cycA E Amino acid permease
AAAAPHLE_02690 1.8e-167 S Alpha/beta hydrolase of unknown function (DUF915)
AAAAPHLE_02691 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
AAAAPHLE_02692 3.2e-138 azoB GM NmrA-like family
AAAAPHLE_02693 9.2e-66 K Winged helix DNA-binding domain
AAAAPHLE_02694 7e-71 spx4 1.20.4.1 P ArsC family
AAAAPHLE_02695 1.7e-66 yeaO S Protein of unknown function, DUF488
AAAAPHLE_02696 4e-53
AAAAPHLE_02697 4.1e-214 mutY L A G-specific adenine glycosylase
AAAAPHLE_02698 1.9e-62
AAAAPHLE_02699 1.6e-85
AAAAPHLE_02700 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
AAAAPHLE_02701 7e-56
AAAAPHLE_02702 2.1e-14
AAAAPHLE_02703 2.8e-114 GM NmrA-like family
AAAAPHLE_02704 3.8e-81 elaA S GNAT family
AAAAPHLE_02705 1.6e-158 EG EamA-like transporter family
AAAAPHLE_02706 1.8e-119 S membrane
AAAAPHLE_02707 1.4e-111 S VIT family
AAAAPHLE_02708 9.1e-189 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
AAAAPHLE_02709 0.0 copB 3.6.3.4 P P-type ATPase
AAAAPHLE_02710 4.7e-73 copR K Copper transport repressor CopY TcrY
AAAAPHLE_02711 2.1e-39
AAAAPHLE_02712 3.5e-73 S COG NOG18757 non supervised orthologous group
AAAAPHLE_02713 1.6e-247 lmrB EGP Major facilitator Superfamily
AAAAPHLE_02714 3.4e-25
AAAAPHLE_02715 4.6e-48
AAAAPHLE_02716 9.4e-65 ycgX S Protein of unknown function (DUF1398)
AAAAPHLE_02717 2.3e-251 U Belongs to the purine-cytosine permease (2.A.39) family
AAAAPHLE_02718 1e-213 mdtG EGP Major facilitator Superfamily
AAAAPHLE_02719 1.1e-180 D Alpha beta
AAAAPHLE_02720 5.8e-77 M1-874 K Domain of unknown function (DUF1836)
AAAAPHLE_02721 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
AAAAPHLE_02722 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
AAAAPHLE_02723 2.1e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
AAAAPHLE_02724 8.4e-152 ywkB S Membrane transport protein
AAAAPHLE_02725 1.8e-164 yvgN C Aldo keto reductase
AAAAPHLE_02726 9.2e-133 thrE S Putative threonine/serine exporter
AAAAPHLE_02727 2e-77 S Threonine/Serine exporter, ThrE
AAAAPHLE_02728 3.2e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AAAAPHLE_02729 2.7e-91 ymdB S Macro domain protein
AAAAPHLE_02730 1.2e-95 K transcriptional regulator
AAAAPHLE_02731 5.5e-50 yvlA
AAAAPHLE_02732 7.9e-161 ypuA S Protein of unknown function (DUF1002)
AAAAPHLE_02733 0.0
AAAAPHLE_02734 1.5e-186 S Bacterial protein of unknown function (DUF916)
AAAAPHLE_02735 7.3e-128 S WxL domain surface cell wall-binding
AAAAPHLE_02736 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
AAAAPHLE_02737 1.2e-88 K Winged helix DNA-binding domain
AAAAPHLE_02738 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
AAAAPHLE_02739 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
AAAAPHLE_02740 1.8e-27
AAAAPHLE_02741 1.8e-283 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
AAAAPHLE_02742 1.5e-75 mltD CBM50 M PFAM NLP P60 protein
AAAAPHLE_02743 2.5e-53
AAAAPHLE_02744 4.2e-62
AAAAPHLE_02746 5.6e-12
AAAAPHLE_02747 5.8e-12 K Cro/C1-type HTH DNA-binding domain
AAAAPHLE_02748 9.5e-109
AAAAPHLE_02749 1.3e-51 S Uncharacterized protein conserved in bacteria (DUF2316)
AAAAPHLE_02750 3.8e-158 4.1.1.46 S Amidohydrolase
AAAAPHLE_02751 1.6e-100 K transcriptional regulator
AAAAPHLE_02752 6.1e-182 yfeX P Peroxidase
AAAAPHLE_02753 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
AAAAPHLE_02754 7.4e-129 ydcF S Gram-negative-bacterium-type cell wall biogenesis
AAAAPHLE_02755 2.4e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
AAAAPHLE_02756 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
AAAAPHLE_02757 9.8e-143 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AAAAPHLE_02758 1.5e-55 txlA O Thioredoxin-like domain
AAAAPHLE_02759 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
AAAAPHLE_02760 1.6e-18
AAAAPHLE_02761 2.8e-94 dps P Belongs to the Dps family
AAAAPHLE_02762 1.6e-32 copZ P Heavy-metal-associated domain
AAAAPHLE_02763 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
AAAAPHLE_02764 0.0 pepO 3.4.24.71 O Peptidase family M13
AAAAPHLE_02765 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AAAAPHLE_02766 8.4e-262 nox C NADH oxidase
AAAAPHLE_02767 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
AAAAPHLE_02768 1.5e-162 S Cell surface protein
AAAAPHLE_02769 1.5e-118 S WxL domain surface cell wall-binding
AAAAPHLE_02770 2.3e-99 S WxL domain surface cell wall-binding
AAAAPHLE_02771 4.6e-45
AAAAPHLE_02772 5.4e-104 K Bacterial regulatory proteins, tetR family
AAAAPHLE_02773 1.5e-49
AAAAPHLE_02774 6.9e-248 S Putative metallopeptidase domain
AAAAPHLE_02775 7e-220 3.1.3.1 S associated with various cellular activities
AAAAPHLE_02776 6.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
AAAAPHLE_02777 0.0 ubiB S ABC1 family
AAAAPHLE_02778 2.9e-249 brnQ U Component of the transport system for branched-chain amino acids
AAAAPHLE_02779 0.0 lacS G Transporter
AAAAPHLE_02780 0.0 lacA 3.2.1.23 G -beta-galactosidase
AAAAPHLE_02781 1.6e-188 lacR K Transcriptional regulator
AAAAPHLE_02782 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
AAAAPHLE_02783 5.6e-231 mdtH P Sugar (and other) transporter
AAAAPHLE_02784 7.9e-304 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
AAAAPHLE_02785 3.6e-230 EGP Major facilitator Superfamily
AAAAPHLE_02786 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
AAAAPHLE_02787 3.5e-101 fic D Fic/DOC family
AAAAPHLE_02788 1.6e-76 K Helix-turn-helix XRE-family like proteins
AAAAPHLE_02789 9.9e-183 galR K Transcriptional regulator
AAAAPHLE_02790 2.7e-282 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
AAAAPHLE_02791 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AAAAPHLE_02792 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AAAAPHLE_02793 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
AAAAPHLE_02794 5.9e-185 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
AAAAPHLE_02795 0.0 rafA 3.2.1.22 G alpha-galactosidase
AAAAPHLE_02796 0.0 lacS G Transporter
AAAAPHLE_02797 1.7e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AAAAPHLE_02798 4.1e-173 galR K Transcriptional regulator
AAAAPHLE_02799 3.7e-193 C Aldo keto reductase family protein
AAAAPHLE_02800 2.4e-65 S pyridoxamine 5-phosphate
AAAAPHLE_02801 0.0 1.3.5.4 C FAD binding domain
AAAAPHLE_02802 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AAAAPHLE_02803 1.7e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AAAAPHLE_02804 2.5e-166 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAAAPHLE_02805 9.2e-175 K Transcriptional regulator, LysR family
AAAAPHLE_02806 1.2e-219 ydiN EGP Major Facilitator Superfamily
AAAAPHLE_02807 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAAAPHLE_02808 9.4e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAAAPHLE_02809 2.3e-156 IQ Enoyl-(Acyl carrier protein) reductase
AAAAPHLE_02810 2.1e-165 G Xylose isomerase-like TIM barrel
AAAAPHLE_02811 4.7e-168 K Transcriptional regulator, LysR family
AAAAPHLE_02812 3.2e-199 EGP Major Facilitator Superfamily
AAAAPHLE_02813 1e-63
AAAAPHLE_02814 4.9e-153 estA S Putative esterase
AAAAPHLE_02815 1.2e-134 K UTRA domain
AAAAPHLE_02816 3.6e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAAAPHLE_02817 3.3e-164 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AAAAPHLE_02818 4e-159 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
AAAAPHLE_02819 1.1e-211 S Bacterial protein of unknown function (DUF871)
AAAAPHLE_02820 1.4e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_02821 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
AAAAPHLE_02822 1.3e-154 licT K CAT RNA binding domain
AAAAPHLE_02823 0.0 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AAAAPHLE_02824 5.1e-223 malY 4.4.1.8 E Aminotransferase class I and II
AAAAPHLE_02825 7.7e-269 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
AAAAPHLE_02826 6.7e-75 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AAAAPHLE_02827 5.4e-78 ptsG 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AAAAPHLE_02828 1.5e-147 yleF K Helix-turn-helix domain, rpiR family
AAAAPHLE_02829 7.2e-246 sacX 2.7.1.193, 2.7.1.211 G phosphotransferase system
AAAAPHLE_02830 5.4e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AAAAPHLE_02831 7.9e-199 4.2.1.126 S Bacterial protein of unknown function (DUF871)
AAAAPHLE_02832 4.9e-292 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_02833 1.9e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_02834 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
AAAAPHLE_02835 3.8e-159 licT K CAT RNA binding domain
AAAAPHLE_02836 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
AAAAPHLE_02837 1.1e-173 K Transcriptional regulator, LacI family
AAAAPHLE_02838 6.1e-271 G Major Facilitator
AAAAPHLE_02839 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
AAAAPHLE_02840 1e-145 yxeH S hydrolase
AAAAPHLE_02841 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AAAAPHLE_02842 2e-115 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AAAAPHLE_02843 2.9e-241 ulaA 2.7.1.194 S PTS system sugar-specific permease component
AAAAPHLE_02844 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
AAAAPHLE_02845 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AAAAPHLE_02846 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AAAAPHLE_02847 1.3e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
AAAAPHLE_02848 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
AAAAPHLE_02849 1.1e-231 gatC G PTS system sugar-specific permease component
AAAAPHLE_02850 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
AAAAPHLE_02851 1.3e-79 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AAAAPHLE_02852 5.2e-123 K DeoR C terminal sensor domain
AAAAPHLE_02853 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
AAAAPHLE_02854 4.5e-70 yueI S Protein of unknown function (DUF1694)
AAAAPHLE_02855 8.2e-102 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
AAAAPHLE_02856 7.8e-266 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
AAAAPHLE_02857 2.3e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
AAAAPHLE_02858 7.8e-307 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
AAAAPHLE_02859 1.6e-255 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
AAAAPHLE_02860 3.1e-206 araR K Transcriptional regulator
AAAAPHLE_02861 7.4e-136 K Helix-turn-helix domain, rpiR family
AAAAPHLE_02862 5.4e-71 yueI S Protein of unknown function (DUF1694)
AAAAPHLE_02863 1.3e-164 I alpha/beta hydrolase fold
AAAAPHLE_02864 1.3e-159 I alpha/beta hydrolase fold
AAAAPHLE_02865 1e-271 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AAAAPHLE_02866 1.2e-206 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AAAAPHLE_02867 1.6e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
AAAAPHLE_02868 1e-148 nanK GK ROK family
AAAAPHLE_02869 3.2e-141 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
AAAAPHLE_02870 9.3e-124 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AAAAPHLE_02871 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
AAAAPHLE_02872 4.2e-70 S Pyrimidine dimer DNA glycosylase
AAAAPHLE_02873 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
AAAAPHLE_02874 3.6e-11
AAAAPHLE_02876 1.9e-291 katA 1.11.1.6 C Belongs to the catalase family
AAAAPHLE_02877 4.9e-78 yneH 1.20.4.1 K ArsC family
AAAAPHLE_02878 5.7e-135 K LytTr DNA-binding domain
AAAAPHLE_02879 1.7e-111 2.7.13.3 T GHKL domain
AAAAPHLE_02880 5.7e-16
AAAAPHLE_02881 1e-97 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
AAAAPHLE_02882 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
AAAAPHLE_02883 5.2e-201 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
AAAAPHLE_02884 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AAAAPHLE_02885 8.7e-72 K Transcriptional regulator
AAAAPHLE_02886 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AAAAPHLE_02887 4.2e-71 yueI S Protein of unknown function (DUF1694)
AAAAPHLE_02888 1e-125 S Membrane
AAAAPHLE_02889 4.6e-165 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
AAAAPHLE_02890 1.3e-256 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
AAAAPHLE_02891 5e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
AAAAPHLE_02892 1.8e-286 rhaB 2.7.1.12, 2.7.1.16, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
AAAAPHLE_02893 3.6e-241 iolF EGP Major facilitator Superfamily
AAAAPHLE_02894 3.8e-179 rhaR K helix_turn_helix, arabinose operon control protein
AAAAPHLE_02895 1.4e-139 K DeoR C terminal sensor domain
AAAAPHLE_02896 4.2e-80 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AAAAPHLE_02897 3.3e-52 sgcB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
AAAAPHLE_02898 1.1e-249 pts36C G PTS system sugar-specific permease component
AAAAPHLE_02900 9.4e-135 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
AAAAPHLE_02901 9.8e-43 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AAAAPHLE_02903 1.1e-24 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
AAAAPHLE_02905 3.8e-182 K Transcriptional regulator, LacI family
AAAAPHLE_02906 2.8e-252 G Major Facilitator
AAAAPHLE_02907 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
AAAAPHLE_02908 1.2e-100 U Protein of unknown function DUF262
AAAAPHLE_02909 5.6e-285 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAAAPHLE_02910 2.4e-156 ypbG 2.7.1.2 GK ROK family
AAAAPHLE_02911 0.0 mngB 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
AAAAPHLE_02912 7.5e-252 S Metal-independent alpha-mannosidase (GH125)
AAAAPHLE_02913 6.3e-196 rliB K Transcriptional regulator
AAAAPHLE_02914 0.0 ypdD G Glycosyl hydrolase family 92
AAAAPHLE_02915 9.1e-217 msmX P Belongs to the ABC transporter superfamily
AAAAPHLE_02916 2.1e-165 scrK 2.7.1.2, 2.7.1.4 GK ROK family
AAAAPHLE_02917 6.3e-271 yesN K helix_turn_helix, arabinose operon control protein
AAAAPHLE_02918 0.0 yesM 2.7.13.3 T Histidine kinase
AAAAPHLE_02919 1.6e-106 ypcB S integral membrane protein
AAAAPHLE_02920 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
AAAAPHLE_02921 9.8e-280 G Domain of unknown function (DUF3502)
AAAAPHLE_02922 1.5e-161 lplC U Binding-protein-dependent transport system inner membrane component
AAAAPHLE_02923 5.2e-181 U Binding-protein-dependent transport system inner membrane component
AAAAPHLE_02924 0.0 3.2.1.52 GH20 G Glycosyl hydrolase family 20, catalytic domain
AAAAPHLE_02925 1.9e-155 K AraC-like ligand binding domain
AAAAPHLE_02926 0.0 mdlA2 V ABC transporter
AAAAPHLE_02927 0.0 yknV V ABC transporter
AAAAPHLE_02928 4.9e-193 rliB K helix_turn_helix gluconate operon transcriptional repressor
AAAAPHLE_02929 6.8e-156 lrp QT PucR C-terminal helix-turn-helix domain
AAAAPHLE_02930 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AAAAPHLE_02931 1.3e-174 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
AAAAPHLE_02932 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
AAAAPHLE_02933 1.1e-86 gutM K Glucitol operon activator protein (GutM)
AAAAPHLE_02934 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
AAAAPHLE_02935 8.5e-145 IQ NAD dependent epimerase/dehydratase family
AAAAPHLE_02936 2.7e-160 rbsU U ribose uptake protein RbsU
AAAAPHLE_02937 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
AAAAPHLE_02938 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AAAAPHLE_02939 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
AAAAPHLE_02940 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)