ORF_ID e_value Gene_name EC_number CAZy COGs Description
ONKNFHMO_00001 6.3e-90 entB 3.5.1.19 Q Isochorismatase family
ONKNFHMO_00002 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
ONKNFHMO_00003 1.2e-180 3.1.21.3 V Type I restriction modification DNA specificity domain
ONKNFHMO_00004 2.4e-178 L Belongs to the 'phage' integrase family
ONKNFHMO_00005 5.1e-196 3.1.21.3 V Type I restriction modification DNA specificity domain
ONKNFHMO_00006 3.1e-300 hsdM 2.1.1.72 V type I restriction-modification system
ONKNFHMO_00007 5.4e-236
ONKNFHMO_00008 6.1e-268 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ONKNFHMO_00010 3.5e-188 yegS 2.7.1.107 G Lipid kinase
ONKNFHMO_00011 2.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ONKNFHMO_00012 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ONKNFHMO_00013 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ONKNFHMO_00014 3.3e-203 camS S sex pheromone
ONKNFHMO_00015 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ONKNFHMO_00016 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
ONKNFHMO_00017 9.4e-214 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ONKNFHMO_00018 3.5e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ONKNFHMO_00019 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
ONKNFHMO_00020 5.5e-141 IQ reductase
ONKNFHMO_00021 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
ONKNFHMO_00022 9.1e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ONKNFHMO_00023 1.2e-143 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ONKNFHMO_00024 1.2e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ONKNFHMO_00025 1.5e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ONKNFHMO_00026 1.9e-147 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ONKNFHMO_00027 1.1e-62 rplQ J Ribosomal protein L17
ONKNFHMO_00028 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ONKNFHMO_00029 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ONKNFHMO_00030 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ONKNFHMO_00031 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
ONKNFHMO_00032 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ONKNFHMO_00033 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ONKNFHMO_00034 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ONKNFHMO_00035 6.8e-64 rplO J Binds to the 23S rRNA
ONKNFHMO_00036 2.9e-24 rpmD J Ribosomal protein L30
ONKNFHMO_00037 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ONKNFHMO_00038 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ONKNFHMO_00039 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ONKNFHMO_00040 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ONKNFHMO_00041 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ONKNFHMO_00042 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ONKNFHMO_00043 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ONKNFHMO_00044 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ONKNFHMO_00045 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ONKNFHMO_00046 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
ONKNFHMO_00047 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ONKNFHMO_00048 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ONKNFHMO_00049 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ONKNFHMO_00050 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ONKNFHMO_00051 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ONKNFHMO_00052 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ONKNFHMO_00053 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
ONKNFHMO_00054 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ONKNFHMO_00055 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
ONKNFHMO_00056 5.4e-200 L Transposase
ONKNFHMO_00057 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ONKNFHMO_00058 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ONKNFHMO_00059 5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ONKNFHMO_00060 2.7e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
ONKNFHMO_00061 1.5e-201 ykiI
ONKNFHMO_00062 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ONKNFHMO_00063 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ONKNFHMO_00064 1e-110 K Bacterial regulatory proteins, tetR family
ONKNFHMO_00065 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ONKNFHMO_00066 3.4e-77 ctsR K Belongs to the CtsR family
ONKNFHMO_00067 1.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
ONKNFHMO_00068 1e-148 S Hydrolases of the alpha beta superfamily
ONKNFHMO_00074 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
ONKNFHMO_00077 2.8e-19
ONKNFHMO_00078 1.3e-263 dtpT U amino acid peptide transporter
ONKNFHMO_00079 5.2e-161 yjjH S Calcineurin-like phosphoesterase
ONKNFHMO_00082 1.5e-115
ONKNFHMO_00083 9.7e-253 EGP Major facilitator Superfamily
ONKNFHMO_00084 2.9e-304 aspT P Predicted Permease Membrane Region
ONKNFHMO_00085 2.5e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
ONKNFHMO_00086 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
ONKNFHMO_00087 1.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ONKNFHMO_00088 3.9e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ONKNFHMO_00089 0.0 yhgF K Tex-like protein N-terminal domain protein
ONKNFHMO_00090 8.6e-86 ydcK S Belongs to the SprT family
ONKNFHMO_00092 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
ONKNFHMO_00093 7.5e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
ONKNFHMO_00094 0.0 S Bacterial membrane protein, YfhO
ONKNFHMO_00095 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ONKNFHMO_00096 6.3e-170 I alpha/beta hydrolase fold
ONKNFHMO_00097 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ONKNFHMO_00098 1.1e-119 tcyB E ABC transporter
ONKNFHMO_00099 2.6e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ONKNFHMO_00100 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
ONKNFHMO_00101 5.4e-269 pepC 3.4.22.40 E Peptidase C1-like family
ONKNFHMO_00102 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ONKNFHMO_00103 8.5e-50 HA62_12640 S GCN5-related N-acetyl-transferase
ONKNFHMO_00104 2.3e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
ONKNFHMO_00105 3.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ONKNFHMO_00106 1e-207 yacL S domain protein
ONKNFHMO_00107 2.6e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
ONKNFHMO_00108 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ONKNFHMO_00109 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ONKNFHMO_00110 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ONKNFHMO_00111 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ONKNFHMO_00112 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
ONKNFHMO_00113 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ONKNFHMO_00114 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ONKNFHMO_00115 7e-228 aadAT EK Aminotransferase, class I
ONKNFHMO_00117 2.1e-249 M Glycosyl transferase family group 2
ONKNFHMO_00118 2.7e-213 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ONKNFHMO_00119 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ONKNFHMO_00120 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ONKNFHMO_00121 3.4e-48
ONKNFHMO_00123 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ONKNFHMO_00124 1.1e-56 K transcriptional regulator PadR family
ONKNFHMO_00125 6.2e-79 XK27_06920 S Protein of unknown function (DUF1700)
ONKNFHMO_00126 1.1e-136 S Putative adhesin
ONKNFHMO_00127 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
ONKNFHMO_00128 1.2e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ONKNFHMO_00129 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ONKNFHMO_00130 3.4e-35 nrdH O Glutaredoxin
ONKNFHMO_00131 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ONKNFHMO_00132 7.3e-309 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ONKNFHMO_00133 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ONKNFHMO_00134 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ONKNFHMO_00135 9.7e-39 S Protein of unknown function (DUF2508)
ONKNFHMO_00136 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ONKNFHMO_00137 7.6e-52 yaaQ S Cyclic-di-AMP receptor
ONKNFHMO_00138 1.5e-186 holB 2.7.7.7 L DNA polymerase III
ONKNFHMO_00139 1.6e-58 yabA L Involved in initiation control of chromosome replication
ONKNFHMO_00140 1.5e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ONKNFHMO_00141 1.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
ONKNFHMO_00142 2.7e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ONKNFHMO_00143 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ONKNFHMO_00144 6.6e-176 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ONKNFHMO_00145 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ONKNFHMO_00146 2.2e-182 S YSIRK type signal peptide
ONKNFHMO_00147 2.8e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ONKNFHMO_00148 1.7e-221 ecsB U ABC transporter
ONKNFHMO_00149 1.2e-137 ecsA V ABC transporter, ATP-binding protein
ONKNFHMO_00150 8.3e-78 hit FG histidine triad
ONKNFHMO_00152 1.2e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ONKNFHMO_00153 0.0 L AAA domain
ONKNFHMO_00154 1.3e-229 yhaO L Ser Thr phosphatase family protein
ONKNFHMO_00155 2.6e-40 yheA S Belongs to the UPF0342 family
ONKNFHMO_00156 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ONKNFHMO_00157 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ONKNFHMO_00158 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ONKNFHMO_00159 8.4e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ONKNFHMO_00161 3.3e-40
ONKNFHMO_00162 1e-43
ONKNFHMO_00163 4.2e-217 folP 2.5.1.15 H dihydropteroate synthase
ONKNFHMO_00164 2.6e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
ONKNFHMO_00165 6.7e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ONKNFHMO_00166 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
ONKNFHMO_00167 1.2e-94 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
ONKNFHMO_00168 1.1e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ONKNFHMO_00169 8.7e-74
ONKNFHMO_00171 1.9e-43
ONKNFHMO_00172 2.8e-120 S CAAX protease self-immunity
ONKNFHMO_00173 2.1e-32
ONKNFHMO_00174 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ONKNFHMO_00175 4.6e-188 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
ONKNFHMO_00176 5.9e-114
ONKNFHMO_00177 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
ONKNFHMO_00178 3.2e-189 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ONKNFHMO_00179 1.9e-86 uspA T Belongs to the universal stress protein A family
ONKNFHMO_00180 8.7e-278 pepV 3.5.1.18 E dipeptidase PepV
ONKNFHMO_00181 1.2e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ONKNFHMO_00182 6.4e-304 ytgP S Polysaccharide biosynthesis protein
ONKNFHMO_00183 4.5e-42
ONKNFHMO_00184 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ONKNFHMO_00185 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ONKNFHMO_00186 2.5e-100 tag 3.2.2.20 L glycosylase
ONKNFHMO_00187 1.5e-29
ONKNFHMO_00188 4.2e-259 EGP Major facilitator Superfamily
ONKNFHMO_00189 4.3e-85 perR P Belongs to the Fur family
ONKNFHMO_00190 2.2e-233 cycA E Amino acid permease
ONKNFHMO_00191 2.6e-103 V VanZ like family
ONKNFHMO_00192 1e-23
ONKNFHMO_00193 2.2e-85 S Short repeat of unknown function (DUF308)
ONKNFHMO_00194 1.5e-79 S Psort location Cytoplasmic, score
ONKNFHMO_00195 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
ONKNFHMO_00196 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
ONKNFHMO_00197 1e-156 yeaE S Aldo keto
ONKNFHMO_00198 4e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
ONKNFHMO_00199 7.3e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
ONKNFHMO_00200 5.8e-151 xth 3.1.11.2 L exodeoxyribonuclease III
ONKNFHMO_00201 1.9e-95 lytE M LysM domain protein
ONKNFHMO_00202 0.0 oppD EP Psort location Cytoplasmic, score
ONKNFHMO_00203 6.8e-43 lytE M LysM domain protein
ONKNFHMO_00204 1.1e-166 sufD O Uncharacterized protein family (UPF0051)
ONKNFHMO_00205 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ONKNFHMO_00206 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
ONKNFHMO_00207 4.2e-240 lmrB EGP Major facilitator Superfamily
ONKNFHMO_00208 1.1e-101 2.3.1.128 K Acetyltransferase (GNAT) domain
ONKNFHMO_00218 1.7e-159 T EAL domain
ONKNFHMO_00219 4e-256 pgaC GT2 M Glycosyl transferase
ONKNFHMO_00220 7.5e-91
ONKNFHMO_00221 1.1e-206 2.7.7.65 T GGDEF domain
ONKNFHMO_00222 9.8e-126 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
ONKNFHMO_00223 6e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
ONKNFHMO_00224 1.7e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
ONKNFHMO_00225 6.3e-94 folT S ECF transporter, substrate-specific component
ONKNFHMO_00226 0.0 pepN 3.4.11.2 E aminopeptidase
ONKNFHMO_00227 9.6e-115 ylbE GM NAD dependent epimerase dehydratase family protein
ONKNFHMO_00228 4.7e-257 pepC 3.4.22.40 E aminopeptidase
ONKNFHMO_00229 2e-211 EGP Major facilitator Superfamily
ONKNFHMO_00230 8.5e-243
ONKNFHMO_00231 6.2e-84 K Transcriptional regulator, HxlR family
ONKNFHMO_00232 6.7e-110 XK27_02070 S Nitroreductase family
ONKNFHMO_00233 2.5e-52 hxlR K Transcriptional regulator, HxlR family
ONKNFHMO_00234 1.4e-121 GM NmrA-like family
ONKNFHMO_00235 2.4e-77 elaA S Gnat family
ONKNFHMO_00236 1.8e-39 S Cytochrome B5
ONKNFHMO_00237 5.4e-09 S Cytochrome B5
ONKNFHMO_00238 1.6e-41 S Cytochrome B5
ONKNFHMO_00239 4.2e-222 yxjG_1 E methionine synthase, vitamin-B12 independent
ONKNFHMO_00240 4.2e-15 S Protein of unknown function (DUF3278)
ONKNFHMO_00241 3.5e-28 WQ51_00220 K Helix-turn-helix XRE-family like proteins
ONKNFHMO_00243 3.2e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ONKNFHMO_00244 1.4e-240 E amino acid
ONKNFHMO_00245 9.2e-258 npp S type I phosphodiesterase nucleotide pyrophosphatase
ONKNFHMO_00246 4.9e-111 yxiO S Vacuole effluxer Atg22 like
ONKNFHMO_00247 2.7e-92 yxiO S Vacuole effluxer Atg22 like
ONKNFHMO_00249 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ONKNFHMO_00250 5.5e-36
ONKNFHMO_00251 1e-290 mntH P H( )-stimulated, divalent metal cation uptake system
ONKNFHMO_00252 1.3e-190 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
ONKNFHMO_00253 1.9e-89 ygfC K transcriptional regulator (TetR family)
ONKNFHMO_00254 4e-174 hrtB V ABC transporter permease
ONKNFHMO_00255 9.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
ONKNFHMO_00256 0.0 yhcA V ABC transporter, ATP-binding protein
ONKNFHMO_00257 2.1e-38
ONKNFHMO_00258 2.4e-50 czrA K Transcriptional regulator, ArsR family
ONKNFHMO_00259 2.5e-255 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ONKNFHMO_00260 5.5e-175 scrR K Transcriptional regulator, LacI family
ONKNFHMO_00261 1e-24
ONKNFHMO_00262 4.3e-104
ONKNFHMO_00263 5.1e-218 yttB EGP Major facilitator Superfamily
ONKNFHMO_00264 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
ONKNFHMO_00265 2.4e-89
ONKNFHMO_00266 9.9e-112 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
ONKNFHMO_00267 7.7e-44 S Putative peptidoglycan binding domain
ONKNFHMO_00268 8.8e-96 S Putative peptidoglycan binding domain
ONKNFHMO_00269 1.4e-124 yciB M ErfK YbiS YcfS YnhG
ONKNFHMO_00271 1.5e-103
ONKNFHMO_00272 7.1e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ONKNFHMO_00273 7e-126 S Alpha beta hydrolase
ONKNFHMO_00274 1.1e-211 gldA 1.1.1.6 C dehydrogenase
ONKNFHMO_00275 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ONKNFHMO_00276 1.3e-41
ONKNFHMO_00277 6.5e-127 pgm3 3.1.3.73 G phosphoglycerate mutase family
ONKNFHMO_00278 9.6e-286 S C4-dicarboxylate anaerobic carrier
ONKNFHMO_00279 2.8e-212 fhaB M Rib/alpha-like repeat
ONKNFHMO_00280 8e-74 L PFAM Integrase catalytic region
ONKNFHMO_00281 6.8e-297 fhaB M Rib/alpha-like repeat
ONKNFHMO_00282 2.2e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ONKNFHMO_00283 1e-265 glnP P ABC transporter
ONKNFHMO_00284 8.5e-139 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ONKNFHMO_00285 7.7e-223 cycA E Amino acid permease
ONKNFHMO_00286 1e-218 nupG F Nucleoside transporter
ONKNFHMO_00287 2.7e-171 rihC 3.2.2.1 F Nucleoside
ONKNFHMO_00288 1.5e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
ONKNFHMO_00289 5.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
ONKNFHMO_00290 7.4e-151 noc K Belongs to the ParB family
ONKNFHMO_00291 3.6e-140 soj D Sporulation initiation inhibitor
ONKNFHMO_00292 5.9e-155 spo0J K Belongs to the ParB family
ONKNFHMO_00293 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
ONKNFHMO_00294 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ONKNFHMO_00295 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
ONKNFHMO_00296 4.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ONKNFHMO_00297 1.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
ONKNFHMO_00298 9.6e-239 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
ONKNFHMO_00299 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
ONKNFHMO_00300 3.9e-173 deoR K sugar-binding domain protein
ONKNFHMO_00301 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ONKNFHMO_00302 3.8e-125 K response regulator
ONKNFHMO_00303 2e-203 hpk31 2.7.13.3 T Histidine kinase
ONKNFHMO_00304 9.7e-137 azlC E AzlC protein
ONKNFHMO_00305 1.6e-52 azlD S branched-chain amino acid
ONKNFHMO_00306 2.9e-115 K DNA-binding transcription factor activity
ONKNFHMO_00307 4.4e-16 K LysR substrate binding domain
ONKNFHMO_00308 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ONKNFHMO_00309 3e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ONKNFHMO_00310 1.1e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ONKNFHMO_00311 4.6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ONKNFHMO_00312 7.9e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ONKNFHMO_00313 1.6e-117 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
ONKNFHMO_00314 2.9e-237 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
ONKNFHMO_00315 1.1e-173 K AI-2E family transporter
ONKNFHMO_00316 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
ONKNFHMO_00317 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
ONKNFHMO_00318 3.5e-134 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
ONKNFHMO_00319 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ONKNFHMO_00320 7.8e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ONKNFHMO_00321 1.1e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ONKNFHMO_00322 6.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
ONKNFHMO_00323 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ONKNFHMO_00324 4.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ONKNFHMO_00325 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ONKNFHMO_00326 2.8e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ONKNFHMO_00327 6.6e-198 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
ONKNFHMO_00328 1.6e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ONKNFHMO_00329 2.2e-298 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
ONKNFHMO_00330 1.2e-246 purD 6.3.4.13 F Belongs to the GARS family
ONKNFHMO_00331 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ONKNFHMO_00332 3.2e-176
ONKNFHMO_00333 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ONKNFHMO_00334 1.9e-38 3.6.1.13, 3.6.1.55 F NUDIX domain
ONKNFHMO_00335 7.2e-183 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
ONKNFHMO_00336 1.5e-90 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
ONKNFHMO_00337 2.5e-36 copZ P PFAM Heavy metal transport detoxification protein
ONKNFHMO_00338 4.8e-99 dps P Belongs to the Dps family
ONKNFHMO_00339 7.6e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
ONKNFHMO_00341 8.6e-184 L Plasmid pRiA4b ORF-3-like protein
ONKNFHMO_00343 6.3e-61 S Protein of unknown function (DUF3021)
ONKNFHMO_00344 1.4e-75 K LytTr DNA-binding domain
ONKNFHMO_00345 1.7e-146 cylB V ABC-2 type transporter
ONKNFHMO_00346 1.1e-158 cylA V ABC transporter
ONKNFHMO_00347 5.7e-52
ONKNFHMO_00348 0.0 XK27_08510 L Type III restriction protein res subunit
ONKNFHMO_00349 3.1e-104 S PFAM Archaeal ATPase
ONKNFHMO_00350 7.9e-70 S PFAM Archaeal ATPase
ONKNFHMO_00351 4.4e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ONKNFHMO_00352 2.3e-207 amtB P ammonium transporter
ONKNFHMO_00353 3e-256 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
ONKNFHMO_00354 1e-84 yvbK 3.1.3.25 K GNAT family
ONKNFHMO_00355 2.5e-92
ONKNFHMO_00356 1.4e-124 pnb C nitroreductase
ONKNFHMO_00357 2.2e-84 ogt 2.1.1.63 L Methyltransferase
ONKNFHMO_00358 9.5e-132 L transposase, IS605 OrfB family
ONKNFHMO_00359 4.2e-77 XK27_00915 C Luciferase-like monooxygenase
ONKNFHMO_00360 1.1e-156 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
ONKNFHMO_00361 5.6e-69 S Protein of unknown function (DUF3021)
ONKNFHMO_00362 2.9e-78 K LytTr DNA-binding domain
ONKNFHMO_00363 2.5e-97 K Acetyltransferase (GNAT) family
ONKNFHMO_00364 3.7e-22
ONKNFHMO_00365 7.6e-121 ybhL S Belongs to the BI1 family
ONKNFHMO_00366 5.8e-82 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
ONKNFHMO_00367 6.3e-201 S Protein of unknown function (DUF3114)
ONKNFHMO_00368 1.3e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ONKNFHMO_00369 2.7e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ONKNFHMO_00370 1.3e-110 yvdD 3.2.2.10 S Belongs to the LOG family
ONKNFHMO_00371 7e-62 S Domain of unknown function (DUF4828)
ONKNFHMO_00372 1.2e-191 mocA S Oxidoreductase
ONKNFHMO_00373 3.6e-233 yfmL 3.6.4.13 L DEAD DEAH box helicase
ONKNFHMO_00375 3.3e-211 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ONKNFHMO_00376 3.6e-54
ONKNFHMO_00377 1.5e-74 gtcA S Teichoic acid glycosylation protein
ONKNFHMO_00378 2.1e-79 fld C Flavodoxin
ONKNFHMO_00379 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
ONKNFHMO_00380 8.4e-223 arcT 2.6.1.1 E Aminotransferase
ONKNFHMO_00381 1.7e-257 E Arginine ornithine antiporter
ONKNFHMO_00382 1.1e-281 yjeM E Amino Acid
ONKNFHMO_00383 8.5e-154 yihY S Belongs to the UPF0761 family
ONKNFHMO_00384 5e-34 S Protein of unknown function (DUF2922)
ONKNFHMO_00385 2.2e-31
ONKNFHMO_00386 9.3e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
ONKNFHMO_00387 1.1e-149 cps1D M Domain of unknown function (DUF4422)
ONKNFHMO_00388 9.8e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
ONKNFHMO_00389 1.7e-122 rfbP 2.7.8.6 M Bacterial sugar transferase
ONKNFHMO_00390 6e-221 glf 5.4.99.9 M UDP-galactopyranose mutase
ONKNFHMO_00391 4.3e-217 cps3F
ONKNFHMO_00392 1.4e-105 M biosynthesis protein
ONKNFHMO_00393 4.9e-260 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
ONKNFHMO_00394 9.3e-200 waaB GT4 M Glycosyl transferases group 1
ONKNFHMO_00395 9.6e-194 M transferase activity, transferring glycosyl groups
ONKNFHMO_00396 1.7e-196 S enterobacterial common antigen metabolic process
ONKNFHMO_00397 1.6e-141 acmD M repeat protein
ONKNFHMO_00398 3.1e-103 M NlpC P60 family protein
ONKNFHMO_00399 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
ONKNFHMO_00400 7.8e-38 L Helix-turn-helix domain
ONKNFHMO_00401 1.1e-115 L PFAM Integrase, catalytic core
ONKNFHMO_00402 1.1e-96 L Helix-turn-helix domain
ONKNFHMO_00403 1.7e-57 L PFAM Integrase catalytic region
ONKNFHMO_00404 2.1e-29 L Transposase
ONKNFHMO_00405 8.2e-250 L Transposase
ONKNFHMO_00406 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ONKNFHMO_00407 8.8e-15
ONKNFHMO_00409 2.4e-170 whiA K May be required for sporulation
ONKNFHMO_00410 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
ONKNFHMO_00411 1.7e-162 rapZ S Displays ATPase and GTPase activities
ONKNFHMO_00412 2.4e-245 steT E amino acid
ONKNFHMO_00413 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ONKNFHMO_00414 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ONKNFHMO_00415 1.5e-13
ONKNFHMO_00416 2.3e-116 yfbR S HD containing hydrolase-like enzyme
ONKNFHMO_00417 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
ONKNFHMO_00418 9.1e-84 ykhA 3.1.2.20 I Thioesterase superfamily
ONKNFHMO_00419 1.6e-165 aatB ET PFAM extracellular solute-binding protein, family 3
ONKNFHMO_00420 1.3e-221 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ONKNFHMO_00421 4.6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ONKNFHMO_00422 1.9e-169 lutA C Cysteine-rich domain
ONKNFHMO_00423 4.4e-296 lutB C 4Fe-4S dicluster domain
ONKNFHMO_00424 2.4e-138 yrjD S LUD domain
ONKNFHMO_00425 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ONKNFHMO_00426 2.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
ONKNFHMO_00427 1.3e-159 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ONKNFHMO_00428 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ONKNFHMO_00429 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
ONKNFHMO_00430 2.4e-32 KT PspC domain protein
ONKNFHMO_00431 9.2e-189 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ONKNFHMO_00432 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ONKNFHMO_00433 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ONKNFHMO_00434 2.6e-126 comFC S Competence protein
ONKNFHMO_00435 2.3e-259 comFA L Helicase C-terminal domain protein
ONKNFHMO_00436 2e-112 yvyE 3.4.13.9 S YigZ family
ONKNFHMO_00437 1.3e-249 EGP Major facilitator Superfamily
ONKNFHMO_00438 3.3e-68 rmaI K Transcriptional regulator
ONKNFHMO_00439 9.2e-40
ONKNFHMO_00440 0.0 ydaO E amino acid
ONKNFHMO_00441 4.3e-305 ybeC E amino acid
ONKNFHMO_00442 4.2e-86 S Aminoacyl-tRNA editing domain
ONKNFHMO_00443 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ONKNFHMO_00444 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ONKNFHMO_00446 6.3e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ONKNFHMO_00447 0.0 uup S ABC transporter, ATP-binding protein
ONKNFHMO_00448 2.9e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
ONKNFHMO_00449 2.8e-159 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ONKNFHMO_00450 5.4e-239 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
ONKNFHMO_00451 1.8e-30 S Protein of unknown function (DUF2929)
ONKNFHMO_00452 0.0 dnaE 2.7.7.7 L DNA polymerase
ONKNFHMO_00453 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
ONKNFHMO_00454 1.6e-168 cvfB S S1 domain
ONKNFHMO_00455 5.7e-166 xerD D recombinase XerD
ONKNFHMO_00456 1.1e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ONKNFHMO_00457 1.9e-141 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ONKNFHMO_00458 1.2e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ONKNFHMO_00459 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ONKNFHMO_00460 5.3e-104 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ONKNFHMO_00461 8e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
ONKNFHMO_00462 1e-273 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
ONKNFHMO_00463 2.5e-13 M Lysin motif
ONKNFHMO_00464 6.9e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
ONKNFHMO_00465 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
ONKNFHMO_00466 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
ONKNFHMO_00467 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ONKNFHMO_00468 3.9e-237 S Tetratricopeptide repeat protein
ONKNFHMO_00469 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ONKNFHMO_00470 0.0 yfmR S ABC transporter, ATP-binding protein
ONKNFHMO_00471 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ONKNFHMO_00472 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ONKNFHMO_00473 5.3e-113 hlyIII S protein, hemolysin III
ONKNFHMO_00474 8.1e-154 DegV S EDD domain protein, DegV family
ONKNFHMO_00475 3.3e-172 ypmR E lipolytic protein G-D-S-L family
ONKNFHMO_00476 7.4e-109 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
ONKNFHMO_00477 1.2e-35 yozE S Belongs to the UPF0346 family
ONKNFHMO_00478 6.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ONKNFHMO_00479 1.2e-143 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ONKNFHMO_00480 3.1e-164 dprA LU DNA protecting protein DprA
ONKNFHMO_00481 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ONKNFHMO_00482 1.2e-171 lacX 5.1.3.3 G Aldose 1-epimerase
ONKNFHMO_00483 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ONKNFHMO_00484 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ONKNFHMO_00485 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ONKNFHMO_00486 8.9e-86 F NUDIX domain
ONKNFHMO_00487 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
ONKNFHMO_00488 4.5e-143 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ONKNFHMO_00489 3.4e-138 cdsA 2.7.7.41 I Belongs to the CDS family
ONKNFHMO_00490 9.8e-236 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
ONKNFHMO_00491 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ONKNFHMO_00492 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ONKNFHMO_00493 1.4e-83 rimP J Required for maturation of 30S ribosomal subunits
ONKNFHMO_00494 1.2e-216 nusA K Participates in both transcription termination and antitermination
ONKNFHMO_00495 1e-44 ylxR K Protein of unknown function (DUF448)
ONKNFHMO_00496 4.5e-49 ylxQ J ribosomal protein
ONKNFHMO_00497 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ONKNFHMO_00498 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ONKNFHMO_00499 1.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ONKNFHMO_00500 1.9e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
ONKNFHMO_00501 2e-64
ONKNFHMO_00502 1.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ONKNFHMO_00503 1.2e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ONKNFHMO_00504 0.0 dnaK O Heat shock 70 kDa protein
ONKNFHMO_00505 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ONKNFHMO_00506 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ONKNFHMO_00507 5.4e-225 3.6.4.12 L Belongs to the 'phage' integrase family
ONKNFHMO_00508 8.1e-142
ONKNFHMO_00509 6.4e-13
ONKNFHMO_00510 4.7e-76
ONKNFHMO_00511 1e-81
ONKNFHMO_00512 1.4e-10 3.4.21.88 K Peptidase S24-like
ONKNFHMO_00513 9.2e-24 3.4.21.88 K Peptidase S24-like
ONKNFHMO_00514 7.9e-279 pipD E Dipeptidase
ONKNFHMO_00515 1.7e-201 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
ONKNFHMO_00516 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ONKNFHMO_00518 7.5e-58
ONKNFHMO_00519 1.6e-182 prmA J Ribosomal protein L11 methyltransferase
ONKNFHMO_00520 1.3e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ONKNFHMO_00521 9.3e-53
ONKNFHMO_00522 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ONKNFHMO_00523 1.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ONKNFHMO_00524 2.8e-170 yniA G Phosphotransferase enzyme family
ONKNFHMO_00525 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
ONKNFHMO_00526 3.5e-137 puuD S peptidase C26
ONKNFHMO_00527 9.2e-169 yvgN C Aldo keto reductase
ONKNFHMO_00528 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
ONKNFHMO_00529 3e-87 hmpT S ECF-type riboflavin transporter, S component
ONKNFHMO_00530 5.3e-264 nox C NADH oxidase
ONKNFHMO_00531 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ONKNFHMO_00532 1.1e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ONKNFHMO_00533 2.6e-90
ONKNFHMO_00534 2.6e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ONKNFHMO_00536 4e-242 L transposase, IS605 OrfB family
ONKNFHMO_00537 1e-81 tlpA2 L Transposase IS200 like
ONKNFHMO_00538 6.4e-139 puuD S peptidase C26
ONKNFHMO_00539 5.5e-248 steT_1 E amino acid
ONKNFHMO_00540 3.3e-13 K Transcriptional regulator, TetR family
ONKNFHMO_00541 1.7e-73 K Transcriptional regulator, TetR family
ONKNFHMO_00542 2.2e-72
ONKNFHMO_00543 2e-275 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
ONKNFHMO_00544 2.7e-277 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
ONKNFHMO_00545 0.0 M domain protein
ONKNFHMO_00546 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
ONKNFHMO_00547 2.3e-267 G Major Facilitator
ONKNFHMO_00548 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ONKNFHMO_00549 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ONKNFHMO_00550 5.5e-261 G Major Facilitator
ONKNFHMO_00551 1.5e-183 K Transcriptional regulator, LacI family
ONKNFHMO_00552 1.3e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ONKNFHMO_00554 2.9e-102 nqr 1.5.1.36 S reductase
ONKNFHMO_00555 7.4e-204 XK27_09615 S reductase
ONKNFHMO_00556 1.9e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
ONKNFHMO_00557 7e-184 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
ONKNFHMO_00558 4.4e-163 rrmA 2.1.1.187 H Methyltransferase
ONKNFHMO_00559 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ONKNFHMO_00560 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
ONKNFHMO_00561 1.2e-10 S Protein of unknown function (DUF4044)
ONKNFHMO_00562 7.8e-58
ONKNFHMO_00563 3.1e-77 mraZ K Belongs to the MraZ family
ONKNFHMO_00564 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ONKNFHMO_00565 1.5e-56 ftsL D Cell division protein FtsL
ONKNFHMO_00566 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
ONKNFHMO_00567 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ONKNFHMO_00568 2.7e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ONKNFHMO_00569 9.2e-206 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ONKNFHMO_00570 3.2e-150 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ONKNFHMO_00571 2.9e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ONKNFHMO_00572 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ONKNFHMO_00573 1.2e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ONKNFHMO_00574 8.3e-41 yggT S YGGT family
ONKNFHMO_00575 1.3e-145 ylmH S S4 domain protein
ONKNFHMO_00576 6.4e-38 divIVA D DivIVA domain protein
ONKNFHMO_00577 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ONKNFHMO_00578 4.2e-32 cspA K Cold shock protein
ONKNFHMO_00579 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
ONKNFHMO_00581 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ONKNFHMO_00582 2.9e-218 iscS 2.8.1.7 E Aminotransferase class V
ONKNFHMO_00583 7.5e-58 XK27_04120 S Putative amino acid metabolism
ONKNFHMO_00584 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ONKNFHMO_00585 3.4e-123 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
ONKNFHMO_00586 3.4e-118 S Repeat protein
ONKNFHMO_00587 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ONKNFHMO_00588 2.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ONKNFHMO_00589 2.7e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ONKNFHMO_00590 7.2e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
ONKNFHMO_00591 1e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ONKNFHMO_00592 2.1e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ONKNFHMO_00593 7e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ONKNFHMO_00594 1.6e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ONKNFHMO_00595 2.3e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ONKNFHMO_00596 2.6e-222 patA 2.6.1.1 E Aminotransferase
ONKNFHMO_00597 6.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ONKNFHMO_00598 1.4e-32 KT Putative sugar diacid recognition
ONKNFHMO_00599 2.9e-27 KT Putative sugar diacid recognition
ONKNFHMO_00600 5.9e-220 EG GntP family permease
ONKNFHMO_00601 1.5e-211 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ONKNFHMO_00602 7.7e-58
ONKNFHMO_00604 3.7e-143 mltD CBM50 M NlpC P60 family protein
ONKNFHMO_00605 5.7e-29
ONKNFHMO_00606 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
ONKNFHMO_00607 9.8e-32 ykzG S Belongs to the UPF0356 family
ONKNFHMO_00608 3.6e-82
ONKNFHMO_00609 5.6e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ONKNFHMO_00610 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
ONKNFHMO_00611 6.2e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
ONKNFHMO_00612 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ONKNFHMO_00613 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
ONKNFHMO_00614 6.1e-48 yktA S Belongs to the UPF0223 family
ONKNFHMO_00615 5.7e-138 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
ONKNFHMO_00616 0.0 typA T GTP-binding protein TypA
ONKNFHMO_00617 8.2e-224 ftsW D Belongs to the SEDS family
ONKNFHMO_00618 1e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
ONKNFHMO_00619 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
ONKNFHMO_00620 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ONKNFHMO_00621 2.6e-163 ylbL T Belongs to the peptidase S16 family
ONKNFHMO_00622 8.1e-82 comEA L Competence protein ComEA
ONKNFHMO_00623 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
ONKNFHMO_00624 0.0 comEC S Competence protein ComEC
ONKNFHMO_00625 2.5e-149 holA 2.7.7.7 L DNA polymerase III delta subunit
ONKNFHMO_00626 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
ONKNFHMO_00627 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ONKNFHMO_00628 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ONKNFHMO_00629 4.9e-165 S Tetratricopeptide repeat
ONKNFHMO_00630 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ONKNFHMO_00631 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ONKNFHMO_00632 6.2e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ONKNFHMO_00633 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
ONKNFHMO_00634 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
ONKNFHMO_00635 7.6e-09
ONKNFHMO_00636 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ONKNFHMO_00637 1.2e-249 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ONKNFHMO_00638 9.8e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ONKNFHMO_00639 2e-157 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ONKNFHMO_00640 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
ONKNFHMO_00641 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ONKNFHMO_00642 2.5e-88
ONKNFHMO_00643 4.4e-46 sip L Belongs to the 'phage' integrase family
ONKNFHMO_00650 1.2e-274 S Phage plasmid primase, P4
ONKNFHMO_00651 5e-12 S head-tail joining protein
ONKNFHMO_00653 1.2e-85 L HNH nucleases
ONKNFHMO_00655 2.1e-79 terS L Phage terminase, small subunit
ONKNFHMO_00656 0.0 terL S overlaps another CDS with the same product name
ONKNFHMO_00658 3.4e-208 S Phage portal protein
ONKNFHMO_00659 2.3e-284 S Caudovirus prohead serine protease
ONKNFHMO_00660 1.5e-76 S Transcriptional regulator, RinA family
ONKNFHMO_00661 1.6e-45 S Phage gp6-like head-tail connector protein
ONKNFHMO_00663 8.4e-130 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ONKNFHMO_00664 1.5e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
ONKNFHMO_00665 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ONKNFHMO_00666 1.3e-35 ynzC S UPF0291 protein
ONKNFHMO_00667 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
ONKNFHMO_00668 1.6e-117 plsC 2.3.1.51 I Acyltransferase
ONKNFHMO_00669 3.7e-142 yabB 2.1.1.223 L Methyltransferase small domain
ONKNFHMO_00670 5.4e-49 yazA L GIY-YIG catalytic domain protein
ONKNFHMO_00671 5.2e-184 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ONKNFHMO_00672 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
ONKNFHMO_00673 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ONKNFHMO_00674 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ONKNFHMO_00675 7.4e-95 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ONKNFHMO_00676 1.9e-245 yifK E Amino acid permease
ONKNFHMO_00677 5.6e-294 clcA P chloride
ONKNFHMO_00678 1.8e-34 secG U Preprotein translocase
ONKNFHMO_00679 2.1e-148 est 3.1.1.1 S Serine aminopeptidase, S33
ONKNFHMO_00680 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ONKNFHMO_00681 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ONKNFHMO_00682 6.3e-105 yxjI
ONKNFHMO_00683 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ONKNFHMO_00684 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
ONKNFHMO_00685 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
ONKNFHMO_00686 6.1e-88 K Acetyltransferase (GNAT) domain
ONKNFHMO_00687 8.9e-77 S PAS domain
ONKNFHMO_00688 9.3e-103 dnaQ 2.7.7.7 L DNA polymerase III
ONKNFHMO_00689 7.3e-169 murB 1.3.1.98 M Cell wall formation
ONKNFHMO_00690 1.2e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ONKNFHMO_00691 6e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ONKNFHMO_00692 3.7e-249 fucP G Major Facilitator Superfamily
ONKNFHMO_00693 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ONKNFHMO_00694 1.2e-126 ybbR S YbbR-like protein
ONKNFHMO_00695 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ONKNFHMO_00696 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ONKNFHMO_00697 8.7e-53
ONKNFHMO_00698 0.0 oatA I Acyltransferase
ONKNFHMO_00699 2.1e-79 K Transcriptional regulator
ONKNFHMO_00700 8.9e-150 XK27_02985 S Cof-like hydrolase
ONKNFHMO_00701 1.8e-78 lytE M Lysin motif
ONKNFHMO_00703 3.8e-136 K response regulator
ONKNFHMO_00704 8.1e-274 yclK 2.7.13.3 T Histidine kinase
ONKNFHMO_00705 5.7e-155 glcU U sugar transport
ONKNFHMO_00706 1.4e-102 lacA 2.3.1.79 S Transferase hexapeptide repeat
ONKNFHMO_00707 5.3e-264 pgi 5.3.1.9 G Belongs to the GPI family
ONKNFHMO_00708 2.1e-26
ONKNFHMO_00710 5.6e-32 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ONKNFHMO_00711 1e-47 gcvH E glycine cleavage
ONKNFHMO_00712 1.1e-220 rodA D Belongs to the SEDS family
ONKNFHMO_00713 2.7e-32 S Protein of unknown function (DUF2969)
ONKNFHMO_00714 1.9e-178 mbl D Cell shape determining protein MreB Mrl
ONKNFHMO_00715 6.5e-243 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ONKNFHMO_00716 1.3e-33 ywzB S Protein of unknown function (DUF1146)
ONKNFHMO_00717 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ONKNFHMO_00718 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ONKNFHMO_00719 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ONKNFHMO_00720 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ONKNFHMO_00721 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ONKNFHMO_00722 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ONKNFHMO_00723 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ONKNFHMO_00724 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
ONKNFHMO_00725 5.9e-233 pyrP F Permease
ONKNFHMO_00726 1.8e-131 yibF S overlaps another CDS with the same product name
ONKNFHMO_00727 3.3e-195 yibE S overlaps another CDS with the same product name
ONKNFHMO_00728 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ONKNFHMO_00729 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ONKNFHMO_00730 9.8e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ONKNFHMO_00731 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ONKNFHMO_00732 1.4e-169 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ONKNFHMO_00733 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ONKNFHMO_00734 6e-108 tdk 2.7.1.21 F thymidine kinase
ONKNFHMO_00735 8.9e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
ONKNFHMO_00736 1.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
ONKNFHMO_00737 1.6e-226 arcD U Amino acid permease
ONKNFHMO_00738 6.8e-262 E Arginine ornithine antiporter
ONKNFHMO_00739 1.2e-79 argR K Regulates arginine biosynthesis genes
ONKNFHMO_00740 4.1e-239 arcA 3.5.3.6 E Arginine
ONKNFHMO_00741 1.1e-197 ampC V Beta-lactamase
ONKNFHMO_00742 4.5e-26
ONKNFHMO_00743 2.5e-39 S Cytochrome B5
ONKNFHMO_00744 2e-27
ONKNFHMO_00745 3.4e-82 S Domain of unknown function (DUF4767)
ONKNFHMO_00746 3.3e-13
ONKNFHMO_00747 1.4e-212 cytX U Belongs to the purine-cytosine permease (2.A.39) family
ONKNFHMO_00748 1.9e-97 wecD3 K PFAM GCN5-related N-acetyltransferase
ONKNFHMO_00749 7.3e-80
ONKNFHMO_00750 4.2e-123 M Lysin motif
ONKNFHMO_00751 7.1e-201 EGP Major facilitator Superfamily
ONKNFHMO_00752 1.2e-85 ywlG S Belongs to the UPF0340 family
ONKNFHMO_00753 3.2e-161 spoU 2.1.1.185 J Methyltransferase
ONKNFHMO_00754 1.3e-224 oxlT P Major Facilitator Superfamily
ONKNFHMO_00755 3.8e-237 L Belongs to the 'phage' integrase family
ONKNFHMO_00756 1.1e-33 S Domain of unknown function (DUF3173)
ONKNFHMO_00758 0.0
ONKNFHMO_00759 1.4e-172
ONKNFHMO_00760 2.1e-85 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ONKNFHMO_00761 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
ONKNFHMO_00762 1.6e-260 G Major Facilitator Superfamily
ONKNFHMO_00763 4.2e-49 V DNA modification
ONKNFHMO_00764 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ONKNFHMO_00766 1.7e-226 S cog cog1373
ONKNFHMO_00767 3.3e-177 coaA 2.7.1.33 F Pantothenic acid kinase
ONKNFHMO_00768 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ONKNFHMO_00769 7e-161 EG EamA-like transporter family
ONKNFHMO_00770 5e-27 Q pyridine nucleotide-disulphide oxidoreductase
ONKNFHMO_00773 5.6e-255 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ONKNFHMO_00774 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ONKNFHMO_00775 2.7e-235 dltB M MBOAT, membrane-bound O-acyltransferase family
ONKNFHMO_00776 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ONKNFHMO_00778 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ONKNFHMO_00779 7.9e-213 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ONKNFHMO_00780 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
ONKNFHMO_00781 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
ONKNFHMO_00782 2.1e-243 codA 3.5.4.1 F cytosine deaminase
ONKNFHMO_00783 3.1e-147 tesE Q hydratase
ONKNFHMO_00784 3.6e-114 S (CBS) domain
ONKNFHMO_00785 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ONKNFHMO_00786 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ONKNFHMO_00787 1.6e-39 yabO J S4 domain protein
ONKNFHMO_00788 2.3e-57 divIC D Septum formation initiator
ONKNFHMO_00789 9.8e-67 yabR J RNA binding
ONKNFHMO_00790 4.3e-269 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ONKNFHMO_00791 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ONKNFHMO_00792 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ONKNFHMO_00793 3.6e-171 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ONKNFHMO_00794 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ONKNFHMO_00795 4.2e-294 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
ONKNFHMO_00796 1.7e-88
ONKNFHMO_00797 1.7e-23
ONKNFHMO_00798 2.8e-185
ONKNFHMO_00799 8.4e-31
ONKNFHMO_00800 1.5e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
ONKNFHMO_00801 2.2e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ONKNFHMO_00802 7.5e-103 fic D Fic/DOC family
ONKNFHMO_00803 5.1e-69
ONKNFHMO_00804 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
ONKNFHMO_00805 8.4e-93 L nuclease
ONKNFHMO_00806 0.0 sbcC L Putative exonuclease SbcCD, C subunit
ONKNFHMO_00807 3e-212 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ONKNFHMO_00808 1.7e-145 ywqE 3.1.3.48 GM PHP domain protein
ONKNFHMO_00809 6.6e-159 snf 2.7.11.1 KL domain protein
ONKNFHMO_00810 0.0 snf 2.7.11.1 KL domain protein
ONKNFHMO_00812 9.6e-149 S Protein of unknown function (DUF3800)
ONKNFHMO_00813 3.2e-11 K transcriptional regulator
ONKNFHMO_00815 4.8e-252 mmuP E amino acid
ONKNFHMO_00816 1.9e-175 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
ONKNFHMO_00817 1.3e-70 O Preprotein translocase subunit SecB
ONKNFHMO_00818 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ONKNFHMO_00819 7.7e-160 endA V DNA/RNA non-specific endonuclease
ONKNFHMO_00820 3.5e-255 yifK E Amino acid permease
ONKNFHMO_00822 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ONKNFHMO_00823 2e-233 N Uncharacterized conserved protein (DUF2075)
ONKNFHMO_00824 6.1e-123 S SNARE associated Golgi protein
ONKNFHMO_00825 0.0 uvrA3 L excinuclease ABC, A subunit
ONKNFHMO_00826 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ONKNFHMO_00827 2.3e-60 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ONKNFHMO_00828 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ONKNFHMO_00829 7.6e-149 S DUF218 domain
ONKNFHMO_00830 0.0 ubiB S ABC1 family
ONKNFHMO_00831 2.2e-246 yhdP S Transporter associated domain
ONKNFHMO_00832 5e-75 copY K Copper transport repressor CopY TcrY
ONKNFHMO_00833 2.3e-246 EGP Major facilitator Superfamily
ONKNFHMO_00834 4.5e-74 yeaL S UPF0756 membrane protein
ONKNFHMO_00835 1.7e-62 yphH S Cupin domain
ONKNFHMO_00836 2.8e-87 C Flavodoxin
ONKNFHMO_00837 2.9e-162 K LysR substrate binding domain protein
ONKNFHMO_00838 6.2e-176 1.1.1.346 C Aldo keto reductase
ONKNFHMO_00839 2.1e-39 gcvR T Belongs to the UPF0237 family
ONKNFHMO_00840 1.6e-244 XK27_08635 S UPF0210 protein
ONKNFHMO_00841 2.5e-129 narI 1.7.5.1 C Nitrate reductase
ONKNFHMO_00842 7.9e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
ONKNFHMO_00843 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
ONKNFHMO_00844 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ONKNFHMO_00845 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
ONKNFHMO_00846 3.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
ONKNFHMO_00847 3.2e-228 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
ONKNFHMO_00848 7.9e-85 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
ONKNFHMO_00849 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
ONKNFHMO_00850 5.1e-44
ONKNFHMO_00851 5.1e-190 comP 2.7.13.3 F Sensor histidine kinase
ONKNFHMO_00852 2.6e-115 nreC K PFAM regulatory protein LuxR
ONKNFHMO_00853 1.6e-18
ONKNFHMO_00854 1.4e-181
ONKNFHMO_00855 1.7e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
ONKNFHMO_00856 3.9e-218 narK P Transporter, major facilitator family protein
ONKNFHMO_00857 4.9e-35 moaD 2.8.1.12 H ThiS family
ONKNFHMO_00858 3.7e-64 moaE 2.8.1.12 H MoaE protein
ONKNFHMO_00859 3.6e-76 S Flavodoxin
ONKNFHMO_00860 1.8e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ONKNFHMO_00861 6.3e-137 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
ONKNFHMO_00862 8.5e-174 fecB P Periplasmic binding protein
ONKNFHMO_00863 6.2e-38 L PFAM Integrase catalytic region
ONKNFHMO_00864 9.6e-75 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
ONKNFHMO_00865 7.2e-81 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
ONKNFHMO_00866 0.0 S Peptidase family M23
ONKNFHMO_00867 3.9e-175 S Phage tail protein
ONKNFHMO_00868 0.0 D NLP P60 protein
ONKNFHMO_00869 9.4e-95 S Phage tail assembly chaperone protein, TAC
ONKNFHMO_00870 5.1e-124
ONKNFHMO_00871 1.1e-71
ONKNFHMO_00872 8.2e-86
ONKNFHMO_00873 3e-53
ONKNFHMO_00874 2.2e-63 S Phage gp6-like head-tail connector protein
ONKNFHMO_00875 8.9e-206 gpG
ONKNFHMO_00876 6.8e-108 S Domain of unknown function (DUF4355)
ONKNFHMO_00878 4.3e-180 S Phage Mu protein F like protein
ONKNFHMO_00879 0.0 S Phage portal protein, SPP1 Gp6-like
ONKNFHMO_00880 1.3e-264 S Phage terminase, large subunit
ONKNFHMO_00882 8e-140 K Belongs to the N(4) N(6)-methyltransferase family
ONKNFHMO_00883 5.7e-71
ONKNFHMO_00884 9.7e-126 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
ONKNFHMO_00887 4.4e-126 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
ONKNFHMO_00888 4.7e-163 mleP3 S Membrane transport protein
ONKNFHMO_00889 2.3e-228 4.4.1.8 E Aminotransferase, class I
ONKNFHMO_00890 5.5e-102 M Protein of unknown function (DUF3737)
ONKNFHMO_00891 8.6e-56 yphJ 4.1.1.44 S decarboxylase
ONKNFHMO_00892 6.3e-11 S Oxidoreductase, aldo keto reductase family protein
ONKNFHMO_00893 1.2e-88 C Flavodoxin
ONKNFHMO_00894 2.1e-160 K Transcriptional regulator
ONKNFHMO_00895 2.6e-89 lacA S transferase hexapeptide repeat
ONKNFHMO_00897 4e-133 S Alpha beta hydrolase
ONKNFHMO_00898 9.2e-155 tesE Q hydratase
ONKNFHMO_00899 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ONKNFHMO_00900 1.1e-228 aadAT EK Aminotransferase, class I
ONKNFHMO_00901 1e-155 ypuA S Protein of unknown function (DUF1002)
ONKNFHMO_00902 6.1e-185 ansA 3.5.1.1 EJ L-asparaginase, type I
ONKNFHMO_00903 2.8e-157 K Transcriptional regulator
ONKNFHMO_00904 2.4e-164 akr5f 1.1.1.346 S reductase
ONKNFHMO_00905 1.8e-104 K Transcriptional regulator C-terminal region
ONKNFHMO_00906 2.1e-189 S membrane
ONKNFHMO_00907 1.6e-114 GM NAD(P)H-binding
ONKNFHMO_00908 1.1e-64 yneR
ONKNFHMO_00909 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
ONKNFHMO_00910 1.4e-220 patA 2.6.1.1 E Aminotransferase
ONKNFHMO_00911 7.7e-208 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ONKNFHMO_00912 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ONKNFHMO_00913 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
ONKNFHMO_00914 7e-181 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
ONKNFHMO_00915 2.3e-147 recO L Involved in DNA repair and RecF pathway recombination
ONKNFHMO_00916 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ONKNFHMO_00917 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
ONKNFHMO_00918 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ONKNFHMO_00919 5.3e-184 phoH T phosphate starvation-inducible protein PhoH
ONKNFHMO_00920 2.4e-181 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ONKNFHMO_00921 4.6e-92 bioY S BioY family
ONKNFHMO_00922 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
ONKNFHMO_00923 9.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
ONKNFHMO_00924 1.7e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ONKNFHMO_00925 2.9e-70 yqeY S YqeY-like protein
ONKNFHMO_00926 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
ONKNFHMO_00927 2.8e-266 glnPH2 P ABC transporter permease
ONKNFHMO_00928 8.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ONKNFHMO_00929 4.2e-178 recT L RecT family
ONKNFHMO_00933 1.8e-17
ONKNFHMO_00934 5e-142 K BRO family, N-terminal domain
ONKNFHMO_00935 8e-31 K Helix-turn-helix XRE-family like proteins
ONKNFHMO_00936 5.3e-72 K Cro/C1-type HTH DNA-binding domain
ONKNFHMO_00937 1e-83 E IrrE N-terminal-like domain
ONKNFHMO_00938 7.6e-30 M Host cell surface-exposed lipoprotein
ONKNFHMO_00939 1.3e-51
ONKNFHMO_00940 2.5e-211 L Belongs to the 'phage' integrase family
ONKNFHMO_00941 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ONKNFHMO_00942 6.8e-262 yfnA E amino acid
ONKNFHMO_00943 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ONKNFHMO_00944 3.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ONKNFHMO_00945 4.1e-40 ylqC S Belongs to the UPF0109 family
ONKNFHMO_00946 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ONKNFHMO_00947 2.7e-250 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ONKNFHMO_00948 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ONKNFHMO_00949 2.2e-181 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ONKNFHMO_00950 0.0 smc D Required for chromosome condensation and partitioning
ONKNFHMO_00951 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ONKNFHMO_00952 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ONKNFHMO_00953 7.3e-189 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ONKNFHMO_00954 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ONKNFHMO_00955 0.0 yloV S DAK2 domain fusion protein YloV
ONKNFHMO_00956 4.7e-58 asp S Asp23 family, cell envelope-related function
ONKNFHMO_00957 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
ONKNFHMO_00958 7.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
ONKNFHMO_00959 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
ONKNFHMO_00960 2.6e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ONKNFHMO_00961 0.0 KLT serine threonine protein kinase
ONKNFHMO_00962 6.9e-133 stp 3.1.3.16 T phosphatase
ONKNFHMO_00963 2e-255 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ONKNFHMO_00964 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ONKNFHMO_00965 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ONKNFHMO_00966 5.1e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ONKNFHMO_00967 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ONKNFHMO_00968 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
ONKNFHMO_00969 1.7e-54
ONKNFHMO_00970 2.3e-264 recN L May be involved in recombinational repair of damaged DNA
ONKNFHMO_00971 1e-78 argR K Regulates arginine biosynthesis genes
ONKNFHMO_00972 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
ONKNFHMO_00973 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ONKNFHMO_00974 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ONKNFHMO_00975 6.7e-203 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ONKNFHMO_00976 3.4e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ONKNFHMO_00977 3.6e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ONKNFHMO_00978 2.2e-70 yqhY S Asp23 family, cell envelope-related function
ONKNFHMO_00979 4.5e-123 J 2'-5' RNA ligase superfamily
ONKNFHMO_00980 1.7e-204 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ONKNFHMO_00981 8.6e-133 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ONKNFHMO_00982 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
ONKNFHMO_00983 7.4e-55 ysxB J Cysteine protease Prp
ONKNFHMO_00984 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
ONKNFHMO_00985 2.6e-112 K Transcriptional regulator
ONKNFHMO_00988 6.5e-90 dut S Protein conserved in bacteria
ONKNFHMO_00989 1.8e-187
ONKNFHMO_00990 2.7e-152
ONKNFHMO_00991 1.3e-51 S Iron-sulfur cluster assembly protein
ONKNFHMO_00992 5e-101 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ONKNFHMO_00993 1.3e-156 P Belongs to the nlpA lipoprotein family
ONKNFHMO_00994 3.9e-12
ONKNFHMO_00995 1.1e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
ONKNFHMO_00996 4e-297 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ONKNFHMO_00997 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
ONKNFHMO_00998 1e-178 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ONKNFHMO_00999 5.9e-22 S Protein of unknown function (DUF3042)
ONKNFHMO_01000 9.1e-68 yqhL P Rhodanese-like protein
ONKNFHMO_01001 1.5e-183 glk 2.7.1.2 G Glucokinase
ONKNFHMO_01002 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
ONKNFHMO_01003 2.2e-114 gluP 3.4.21.105 S Peptidase, S54 family
ONKNFHMO_01004 1.4e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ONKNFHMO_01005 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ONKNFHMO_01006 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
ONKNFHMO_01007 0.0 S membrane
ONKNFHMO_01008 4e-71 yneR S Belongs to the HesB IscA family
ONKNFHMO_01009 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ONKNFHMO_01010 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
ONKNFHMO_01011 6.9e-113 rlpA M PFAM NLP P60 protein
ONKNFHMO_01012 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ONKNFHMO_01013 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ONKNFHMO_01014 2.6e-58 yodB K Transcriptional regulator, HxlR family
ONKNFHMO_01015 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
ONKNFHMO_01016 2.2e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ONKNFHMO_01017 8.2e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
ONKNFHMO_01018 1.5e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ONKNFHMO_01019 9.3e-71 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
ONKNFHMO_01020 7.8e-236 V MatE
ONKNFHMO_01021 1.8e-268 yjeM E Amino Acid
ONKNFHMO_01022 9.8e-280 arlS 2.7.13.3 T Histidine kinase
ONKNFHMO_01023 1.5e-121 K response regulator
ONKNFHMO_01024 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ONKNFHMO_01025 2.9e-99 yceD S Uncharacterized ACR, COG1399
ONKNFHMO_01026 2.9e-215 ylbM S Belongs to the UPF0348 family
ONKNFHMO_01027 1.4e-141 yqeM Q Methyltransferase
ONKNFHMO_01028 1.3e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ONKNFHMO_01029 9.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
ONKNFHMO_01030 7.9e-125 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ONKNFHMO_01031 1.9e-47 yhbY J RNA-binding protein
ONKNFHMO_01032 5.6e-219 yqeH S Ribosome biogenesis GTPase YqeH
ONKNFHMO_01033 2.8e-96 yqeG S HAD phosphatase, family IIIA
ONKNFHMO_01034 4.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ONKNFHMO_01035 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
ONKNFHMO_01036 6.3e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ONKNFHMO_01037 1e-173 dnaI L Primosomal protein DnaI
ONKNFHMO_01038 3.2e-208 dnaB L replication initiation and membrane attachment
ONKNFHMO_01039 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ONKNFHMO_01040 9.3e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ONKNFHMO_01041 8.8e-161 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ONKNFHMO_01042 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ONKNFHMO_01043 1.8e-119 yoaK S Protein of unknown function (DUF1275)
ONKNFHMO_01044 1.4e-119 ybhL S Belongs to the BI1 family
ONKNFHMO_01045 1.2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
ONKNFHMO_01046 2.9e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ONKNFHMO_01047 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ONKNFHMO_01048 7.5e-58 ytzB S Small secreted protein
ONKNFHMO_01049 2.6e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
ONKNFHMO_01050 1.1e-186 iolS C Aldo keto reductase
ONKNFHMO_01051 3.5e-293 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
ONKNFHMO_01052 1.5e-09
ONKNFHMO_01053 3.8e-88 L HNH nucleases
ONKNFHMO_01054 5e-84 L Phage terminase, small subunit
ONKNFHMO_01056 1.5e-09
ONKNFHMO_01057 0.0 S Phage Terminase
ONKNFHMO_01058 4e-223 S Phage portal protein
ONKNFHMO_01059 2.3e-128 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
ONKNFHMO_01060 3.6e-208 S Phage capsid family
ONKNFHMO_01061 4.6e-61 S Phage gp6-like head-tail connector protein
ONKNFHMO_01062 1.2e-58 S Phage head-tail joining protein
ONKNFHMO_01063 5.5e-71 S Bacteriophage HK97-gp10, putative tail-component
ONKNFHMO_01064 3.4e-67 S Protein of unknown function (DUF806)
ONKNFHMO_01065 4.2e-135 S Phage tail tube protein
ONKNFHMO_01066 1.1e-62 S Phage tail assembly chaperone proteins, TAC
ONKNFHMO_01067 0.0 M Phage tail tape measure protein TP901
ONKNFHMO_01068 7.6e-160 S Phage tail protein
ONKNFHMO_01069 0.0 spr M Prophage endopeptidase tail
ONKNFHMO_01070 6.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ONKNFHMO_01071 1.6e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
ONKNFHMO_01072 5.2e-262 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ONKNFHMO_01073 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
ONKNFHMO_01074 3.7e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
ONKNFHMO_01075 8.8e-286 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
ONKNFHMO_01076 2e-100 maa 2.3.1.79 S Maltose O-acetyltransferase
ONKNFHMO_01077 2.2e-159 ytbE 1.1.1.346 S Aldo keto reductase
ONKNFHMO_01078 1.5e-208 araR K Transcriptional regulator
ONKNFHMO_01079 4.3e-83 usp6 T universal stress protein
ONKNFHMO_01080 4.4e-46
ONKNFHMO_01081 3.4e-244 rarA L recombination factor protein RarA
ONKNFHMO_01082 1.7e-87 yueI S Protein of unknown function (DUF1694)
ONKNFHMO_01083 1e-20
ONKNFHMO_01084 1.6e-75 4.4.1.5 E Glyoxalase
ONKNFHMO_01085 2.5e-138 S Membrane
ONKNFHMO_01086 1.1e-141 S Belongs to the UPF0246 family
ONKNFHMO_01087 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
ONKNFHMO_01088 6.7e-164 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
ONKNFHMO_01089 5e-84
ONKNFHMO_01090 2.2e-190 lacR K Transcriptional regulator
ONKNFHMO_01091 0.0 lacS G Transporter
ONKNFHMO_01092 0.0 lacZ 3.2.1.23 G -beta-galactosidase
ONKNFHMO_01093 1.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ONKNFHMO_01094 6.8e-159 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
ONKNFHMO_01095 1.3e-144 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
ONKNFHMO_01096 7.7e-224 yxjG_1 E methionine synthase, vitamin-B12 independent
ONKNFHMO_01097 2.8e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ONKNFHMO_01098 8.2e-224 mdtG EGP Major facilitator Superfamily
ONKNFHMO_01099 1.2e-168 T Calcineurin-like phosphoesterase superfamily domain
ONKNFHMO_01100 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ONKNFHMO_01103 1.2e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
ONKNFHMO_01104 3e-143 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
ONKNFHMO_01105 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
ONKNFHMO_01106 0.0 trxB2 1.8.1.9 C Thioredoxin domain
ONKNFHMO_01107 3.6e-45 L PFAM Integrase catalytic region
ONKNFHMO_01108 6.7e-40 S dextransucrase activity
ONKNFHMO_01109 3.5e-282 ganB 3.2.1.89 G arabinogalactan
ONKNFHMO_01110 2.1e-171 3.2.1.23, 3.2.1.89 G arabinogalactan endo-1,4-beta-galactosidase activity
ONKNFHMO_01111 1.2e-64 gntR1 K Transcriptional regulator, GntR family
ONKNFHMO_01112 7.7e-160 V ABC transporter, ATP-binding protein
ONKNFHMO_01113 2.6e-118
ONKNFHMO_01114 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
ONKNFHMO_01115 1.7e-100 S Pfam:DUF3816
ONKNFHMO_01116 0.0 clpE O Belongs to the ClpA ClpB family
ONKNFHMO_01117 2.2e-27
ONKNFHMO_01118 2.7e-39 ptsH G phosphocarrier protein HPR
ONKNFHMO_01119 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ONKNFHMO_01120 1.2e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
ONKNFHMO_01121 1.6e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
ONKNFHMO_01122 1.3e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ONKNFHMO_01123 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
ONKNFHMO_01124 8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ONKNFHMO_01125 4.6e-41 rpmE2 J Ribosomal protein L31
ONKNFHMO_01126 6.1e-241 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ONKNFHMO_01127 2.7e-168 S Alpha/beta hydrolase of unknown function (DUF915)
ONKNFHMO_01128 5.1e-125 srtA 3.4.22.70 M sortase family
ONKNFHMO_01129 1e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ONKNFHMO_01130 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
ONKNFHMO_01131 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
ONKNFHMO_01132 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ONKNFHMO_01133 7e-93 lemA S LemA family
ONKNFHMO_01134 8.9e-159 htpX O Belongs to the peptidase M48B family
ONKNFHMO_01135 5.2e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ONKNFHMO_01136 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ONKNFHMO_01137 1.4e-153 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ONKNFHMO_01138 2.4e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
ONKNFHMO_01139 1.3e-165 recT L RecT family
ONKNFHMO_01144 6.5e-33
ONKNFHMO_01147 4.7e-140 K BRO family, N-terminal domain
ONKNFHMO_01148 3.4e-32 K Helix-turn-helix XRE-family like proteins
ONKNFHMO_01149 3e-47 3.4.21.88 K Helix-turn-helix domain
ONKNFHMO_01150 1.6e-70 S Pfam:DUF955
ONKNFHMO_01151 8e-75
ONKNFHMO_01153 2.6e-139
ONKNFHMO_01154 2.7e-238 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
ONKNFHMO_01155 9.1e-201 gntT EG Gluconate
ONKNFHMO_01156 1.4e-184 K Transcriptional regulator, LacI family
ONKNFHMO_01157 1.8e-292 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ONKNFHMO_01158 2.9e-96
ONKNFHMO_01159 2.1e-25
ONKNFHMO_01160 1.1e-62 asp S Asp23 family, cell envelope-related function
ONKNFHMO_01161 4.4e-91 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
ONKNFHMO_01163 3.8e-32
ONKNFHMO_01164 8.3e-69 yqkB S Belongs to the HesB IscA family
ONKNFHMO_01165 1.2e-180
ONKNFHMO_01166 1.2e-76
ONKNFHMO_01167 5.9e-88 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
ONKNFHMO_01169 1.1e-52 XK27_01125 L PFAM IS66 Orf2 family protein
ONKNFHMO_01170 2.1e-293 L Transposase IS66 family
ONKNFHMO_01171 0.0 S SEC-C Motif Domain Protein
ONKNFHMO_01172 1.6e-51
ONKNFHMO_01173 4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ONKNFHMO_01174 4.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ONKNFHMO_01175 6.5e-119 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ONKNFHMO_01176 4.2e-231 clcA_2 P Chloride transporter, ClC family
ONKNFHMO_01177 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
ONKNFHMO_01178 8.7e-116 lssY 3.6.1.27 I Acid phosphatase homologues
ONKNFHMO_01195 4.9e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
ONKNFHMO_01196 1.6e-140 accA 2.1.3.15, 6.4.1.2 I alpha subunit
ONKNFHMO_01197 6.5e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ONKNFHMO_01198 3.2e-261 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
ONKNFHMO_01199 1e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ONKNFHMO_01200 2.1e-76 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ONKNFHMO_01201 5.6e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ONKNFHMO_01202 1.3e-131 IQ reductase
ONKNFHMO_01203 3.3e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
ONKNFHMO_01204 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ONKNFHMO_01205 3.8e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ONKNFHMO_01206 4.2e-77 marR K Transcriptional regulator, MarR family
ONKNFHMO_01207 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ONKNFHMO_01209 4.6e-202 xerS L Belongs to the 'phage' integrase family
ONKNFHMO_01210 2.5e-155 KT YcbB domain
ONKNFHMO_01211 2.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ONKNFHMO_01212 1.5e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
ONKNFHMO_01213 3.2e-164 EG EamA-like transporter family
ONKNFHMO_01214 2e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
ONKNFHMO_01215 7.6e-48 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ONKNFHMO_01216 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ONKNFHMO_01217 0.0 copA 3.6.3.54 P P-type ATPase
ONKNFHMO_01218 1.6e-90
ONKNFHMO_01220 3.6e-57
ONKNFHMO_01221 1.1e-240 yjcE P Sodium proton antiporter
ONKNFHMO_01226 6.2e-193
ONKNFHMO_01227 5.2e-98 2.3.1.128 K acetyltransferase
ONKNFHMO_01228 7.5e-114 manA 5.3.1.8 G mannose-6-phosphate isomerase
ONKNFHMO_01229 2.7e-163 K LysR substrate binding domain
ONKNFHMO_01230 5.2e-209 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
ONKNFHMO_01231 1.2e-54 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ONKNFHMO_01232 1.6e-183
ONKNFHMO_01233 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ONKNFHMO_01234 2e-184 S Phosphotransferase system, EIIC
ONKNFHMO_01235 1.7e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
ONKNFHMO_01236 7.1e-158 XK27_04590 S NADPH-dependent FMN reductase
ONKNFHMO_01237 1e-78 fld C Flavodoxin
ONKNFHMO_01238 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
ONKNFHMO_01239 3.1e-93 P Cadmium resistance transporter
ONKNFHMO_01240 3.1e-121 pgm1 3.1.3.73 G phosphoglycerate mutase
ONKNFHMO_01241 1.9e-149 3.1.3.48 T Pfam:Y_phosphatase3C
ONKNFHMO_01242 5.5e-56 pduU E BMC
ONKNFHMO_01243 2.2e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ONKNFHMO_01244 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
ONKNFHMO_01245 3.1e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
ONKNFHMO_01246 7.4e-80 pduO S Haem-degrading
ONKNFHMO_01247 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
ONKNFHMO_01248 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
ONKNFHMO_01249 6.4e-90 S Putative propanediol utilisation
ONKNFHMO_01250 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
ONKNFHMO_01251 7.6e-43 pduA_4 CQ BMC
ONKNFHMO_01252 5.1e-75 pduK CQ BMC
ONKNFHMO_01253 1.7e-60 pduH S Dehydratase medium subunit
ONKNFHMO_01254 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
ONKNFHMO_01255 2.1e-80 pduE 4.2.1.28 Q Dehydratase small subunit
ONKNFHMO_01256 3.8e-128 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
ONKNFHMO_01257 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
ONKNFHMO_01258 2.7e-134 pduB E BMC
ONKNFHMO_01259 6.2e-42 pduA_4 CQ BMC
ONKNFHMO_01260 3e-201 K helix_turn_helix, arabinose operon control protein
ONKNFHMO_01261 4.1e-150 eutJ E Hsp70 protein
ONKNFHMO_01262 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
ONKNFHMO_01263 9e-167
ONKNFHMO_01264 3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
ONKNFHMO_01265 1.8e-177 S AI-2E family transporter
ONKNFHMO_01266 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
ONKNFHMO_01267 1.7e-78 yybA 2.3.1.57 K Transcriptional regulator
ONKNFHMO_01268 6.1e-91 M1-874 K Domain of unknown function (DUF1836)
ONKNFHMO_01269 7.2e-92 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
ONKNFHMO_01270 4.7e-157 ypdB V (ABC) transporter
ONKNFHMO_01271 1.1e-242 yhdP S Transporter associated domain
ONKNFHMO_01272 9.9e-85 nrdI F Belongs to the NrdI family
ONKNFHMO_01273 1.4e-74 S 3-demethylubiquinone-9 3-methyltransferase
ONKNFHMO_01274 2.9e-194 yeaN P Transporter, major facilitator family protein
ONKNFHMO_01275 5.7e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ONKNFHMO_01276 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ONKNFHMO_01277 1.1e-40
ONKNFHMO_01278 0.0 lacS G Transporter
ONKNFHMO_01279 1.5e-80 uspA T universal stress protein
ONKNFHMO_01280 1.5e-80 K AsnC family
ONKNFHMO_01281 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ONKNFHMO_01282 1.7e-103 dedA 3.1.3.1 S SNARE associated Golgi protein
ONKNFHMO_01283 9.8e-82 L transposase and inactivated derivatives, IS30 family
ONKNFHMO_01284 2.8e-108 tra L Transposase and inactivated derivatives, IS30 family
ONKNFHMO_01285 3.7e-182 galR K Transcriptional regulator
ONKNFHMO_01286 1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ONKNFHMO_01287 1.2e-227 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ONKNFHMO_01288 2.2e-187 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
ONKNFHMO_01289 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
ONKNFHMO_01290 4.3e-94 yxkA S Phosphatidylethanolamine-binding protein
ONKNFHMO_01291 9.1e-36
ONKNFHMO_01292 9.1e-53
ONKNFHMO_01293 4.6e-205
ONKNFHMO_01294 1.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ONKNFHMO_01295 1.8e-136 pnuC H nicotinamide mononucleotide transporter
ONKNFHMO_01296 9.9e-160 ytbE 1.1.1.346 S Aldo keto reductase
ONKNFHMO_01297 3.4e-126 K response regulator
ONKNFHMO_01298 8.7e-184 T Histidine kinase-like ATPases
ONKNFHMO_01299 6.8e-136 macB2 V ABC transporter, ATP-binding protein
ONKNFHMO_01300 0.0 ysaB V FtsX-like permease family
ONKNFHMO_01301 7.4e-160 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
ONKNFHMO_01302 1.8e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ONKNFHMO_01303 2.2e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ONKNFHMO_01304 3.9e-199 EGP Major facilitator Superfamily
ONKNFHMO_01305 1.5e-91 ymdB S Macro domain protein
ONKNFHMO_01306 3.9e-113 K Helix-turn-helix XRE-family like proteins
ONKNFHMO_01307 0.0 pepO 3.4.24.71 O Peptidase family M13
ONKNFHMO_01308 3.6e-48
ONKNFHMO_01309 5.6e-247 S Putative metallopeptidase domain
ONKNFHMO_01310 1.4e-209 3.1.3.1 S associated with various cellular activities
ONKNFHMO_01311 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
ONKNFHMO_01312 1.4e-65 yeaO S Protein of unknown function, DUF488
ONKNFHMO_01314 6e-123 yrkL S Flavodoxin-like fold
ONKNFHMO_01315 1.6e-54
ONKNFHMO_01316 3.3e-18 S Domain of unknown function (DUF4767)
ONKNFHMO_01317 2.4e-141 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ONKNFHMO_01318 1.1e-49
ONKNFHMO_01319 1.4e-206 nrnB S DHHA1 domain
ONKNFHMO_01320 1.3e-232 S Uncharacterized protein conserved in bacteria (DUF2325)
ONKNFHMO_01321 9.9e-250 brnQ U Component of the transport system for branched-chain amino acids
ONKNFHMO_01322 1.5e-106 NU mannosyl-glycoprotein
ONKNFHMO_01323 1.8e-147 S Putative ABC-transporter type IV
ONKNFHMO_01324 4.4e-275 S ABC transporter, ATP-binding protein
ONKNFHMO_01325 2.9e-11
ONKNFHMO_01327 1e-108 S Protein of unknown function (DUF3278)
ONKNFHMO_01328 7.8e-14 relB L RelB antitoxin
ONKNFHMO_01330 1e-78 M PFAM NLP P60 protein
ONKNFHMO_01331 9.8e-183 ABC-SBP S ABC transporter
ONKNFHMO_01332 8.6e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
ONKNFHMO_01333 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
ONKNFHMO_01334 5.1e-96 P Cadmium resistance transporter
ONKNFHMO_01335 5.2e-56 K Transcriptional regulator, ArsR family
ONKNFHMO_01336 1e-240 mepA V MATE efflux family protein
ONKNFHMO_01337 1.5e-55 trxA O Belongs to the thioredoxin family
ONKNFHMO_01338 2.3e-131 terC P membrane
ONKNFHMO_01339 7.4e-177 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ONKNFHMO_01340 9.7e-169 corA P CorA-like Mg2+ transporter protein
ONKNFHMO_01341 2.6e-285 pipD E Dipeptidase
ONKNFHMO_01342 1.9e-242 pbuX F xanthine permease
ONKNFHMO_01343 1.9e-248 nhaC C Na H antiporter NhaC
ONKNFHMO_01344 7.1e-250 hisS 6.1.1.21 J histidyl-tRNA synthetase
ONKNFHMO_01345 2.5e-97 S Family of unknown function (DUF5449)
ONKNFHMO_01346 1.7e-184 4.1.1.22 H Histidine carboxylase PI chain
ONKNFHMO_01347 5.5e-267 aaxC E Arginine ornithine antiporter
ONKNFHMO_01351 2e-94
ONKNFHMO_01352 2.2e-69 K Transcriptional regulator, HxlR family
ONKNFHMO_01353 2.3e-171 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ONKNFHMO_01354 6e-22 epsB M biosynthesis protein
ONKNFHMO_01355 7.9e-168 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ONKNFHMO_01356 1.8e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ONKNFHMO_01357 2.8e-264 S Protein of unknown function (DUF2971)
ONKNFHMO_01358 6.3e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
ONKNFHMO_01359 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
ONKNFHMO_01360 1.9e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ONKNFHMO_01361 2.9e-134 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ONKNFHMO_01362 3.5e-230 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ONKNFHMO_01363 1.4e-139 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ONKNFHMO_01364 3.6e-148 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
ONKNFHMO_01365 4.3e-230 mtnE 2.6.1.83 E Aminotransferase
ONKNFHMO_01366 1.9e-186 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ONKNFHMO_01367 3.5e-58 L Helix-turn-helix domain
ONKNFHMO_01368 6.5e-57 L Helix-turn-helix domain
ONKNFHMO_01369 6.7e-278 pipD E Dipeptidase
ONKNFHMO_01370 0.0 yjbQ P TrkA C-terminal domain protein
ONKNFHMO_01371 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
ONKNFHMO_01372 5.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ONKNFHMO_01373 4e-92
ONKNFHMO_01374 1.7e-37
ONKNFHMO_01375 1.2e-105 K DNA-templated transcription, initiation
ONKNFHMO_01376 4e-28
ONKNFHMO_01377 2.4e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
ONKNFHMO_01378 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ONKNFHMO_01379 4e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
ONKNFHMO_01380 5.1e-116 yjbH Q Thioredoxin
ONKNFHMO_01381 1.5e-269 pipD E Dipeptidase
ONKNFHMO_01382 3.8e-206 coiA 3.6.4.12 S Competence protein
ONKNFHMO_01383 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
ONKNFHMO_01384 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ONKNFHMO_01385 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
ONKNFHMO_01386 2.3e-306 S AAA domain, putative AbiEii toxin, Type IV TA system
ONKNFHMO_01387 4.8e-207 3.6.4.12 L DNA helicase
ONKNFHMO_01388 3.1e-231 L Integrase core domain
ONKNFHMO_01389 1.3e-139 L Bacterial dnaA protein
ONKNFHMO_01390 7e-159
ONKNFHMO_01392 7.7e-160 metQ_4 P Belongs to the nlpA lipoprotein family
ONKNFHMO_01393 1.5e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ONKNFHMO_01394 6.9e-127 O Zinc-dependent metalloprotease
ONKNFHMO_01395 1.9e-115 S Membrane
ONKNFHMO_01396 1.9e-200 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
ONKNFHMO_01397 5.7e-174 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
ONKNFHMO_01400 5e-22 S Phage derived protein Gp49-like (DUF891)
ONKNFHMO_01401 1.7e-47 L Belongs to the 'phage' integrase family
ONKNFHMO_01403 2.3e-36 S Lipopolysaccharide assembly protein A domain
ONKNFHMO_01404 3.7e-159 3.1.3.102, 3.1.3.104 S hydrolase
ONKNFHMO_01405 1.2e-90 ntd 2.4.2.6 F Nucleoside
ONKNFHMO_01406 7.5e-21
ONKNFHMO_01407 1.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
ONKNFHMO_01408 4.3e-115 yviA S Protein of unknown function (DUF421)
ONKNFHMO_01409 1.9e-29 S Protein of unknown function (DUF3290)
ONKNFHMO_01410 2e-28 S Protein of unknown function (DUF3290)
ONKNFHMO_01411 3.5e-42 ybaN S Protein of unknown function (DUF454)
ONKNFHMO_01412 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ONKNFHMO_01413 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ONKNFHMO_01414 2.1e-288 S Psort location CytoplasmicMembrane, score
ONKNFHMO_01415 1.4e-164 yueF S AI-2E family transporter
ONKNFHMO_01416 8.9e-77
ONKNFHMO_01419 1.3e-07
ONKNFHMO_01428 3.8e-59
ONKNFHMO_01429 7e-153 L Psort location Cytoplasmic, score
ONKNFHMO_01430 9.1e-103 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
ONKNFHMO_01432 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ONKNFHMO_01433 7.1e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
ONKNFHMO_01434 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ONKNFHMO_01435 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ONKNFHMO_01436 1.8e-40 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
ONKNFHMO_01437 3e-24
ONKNFHMO_01438 1.1e-19 relB L Addiction module antitoxin, RelB DinJ family
ONKNFHMO_01439 7.5e-91 XK27_08850 J Aminoacyl-tRNA editing domain
ONKNFHMO_01440 1e-56 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
ONKNFHMO_01441 7.7e-199 V Beta-lactamase
ONKNFHMO_01442 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ONKNFHMO_01443 1.7e-122 yhiD S MgtC family
ONKNFHMO_01444 4e-121 S GyrI-like small molecule binding domain
ONKNFHMO_01446 6.1e-125 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
ONKNFHMO_01447 3.2e-50 azlD E Branched-chain amino acid transport
ONKNFHMO_01448 2e-121 azlC E azaleucine resistance protein AzlC
ONKNFHMO_01449 2.6e-266 K Aminotransferase class I and II
ONKNFHMO_01450 1.9e-305 S amidohydrolase
ONKNFHMO_01451 1.6e-165 S reductase
ONKNFHMO_01452 1.6e-93 2.3.1.183 M Acetyltransferase GNAT family
ONKNFHMO_01453 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
ONKNFHMO_01454 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
ONKNFHMO_01455 4.8e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ONKNFHMO_01456 0.0 asnB 6.3.5.4 E Asparagine synthase
ONKNFHMO_01457 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ONKNFHMO_01458 7.1e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ONKNFHMO_01459 4.1e-136 jag S R3H domain protein
ONKNFHMO_01460 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ONKNFHMO_01461 1.2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ONKNFHMO_01462 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
ONKNFHMO_01463 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ONKNFHMO_01464 2.9e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ONKNFHMO_01465 1.7e-34 yaaA S S4 domain protein YaaA
ONKNFHMO_01466 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ONKNFHMO_01467 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ONKNFHMO_01468 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ONKNFHMO_01469 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
ONKNFHMO_01470 7.5e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ONKNFHMO_01471 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ONKNFHMO_01472 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
ONKNFHMO_01473 2e-74 rplI J Binds to the 23S rRNA
ONKNFHMO_01474 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ONKNFHMO_01475 6.9e-207 yttB EGP Major facilitator Superfamily
ONKNFHMO_01476 1.5e-60
ONKNFHMO_01477 2.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
ONKNFHMO_01478 3.1e-101 K DNA-binding helix-turn-helix protein
ONKNFHMO_01480 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
ONKNFHMO_01481 0.0 lmrA 3.6.3.44 V ABC transporter
ONKNFHMO_01483 3.1e-130 K response regulator
ONKNFHMO_01484 0.0 vicK 2.7.13.3 T Histidine kinase
ONKNFHMO_01485 4.9e-251 yycH S YycH protein
ONKNFHMO_01486 2.6e-152 yycI S YycH protein
ONKNFHMO_01487 1.2e-154 vicX 3.1.26.11 S domain protein
ONKNFHMO_01488 6.4e-219 htrA 3.4.21.107 O serine protease
ONKNFHMO_01489 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
ONKNFHMO_01490 8.2e-182 ABC-SBP S ABC transporter
ONKNFHMO_01491 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ONKNFHMO_01493 2.9e-96 S reductase
ONKNFHMO_01494 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
ONKNFHMO_01495 7.5e-155 glcU U sugar transport
ONKNFHMO_01496 6.5e-150 E Glyoxalase-like domain
ONKNFHMO_01497 4.1e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ONKNFHMO_01498 2.1e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
ONKNFHMO_01499 1.4e-145 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ONKNFHMO_01500 2e-129 V ABC transporter
ONKNFHMO_01501 2.8e-219 bacI V MacB-like periplasmic core domain
ONKNFHMO_01503 2.5e-20
ONKNFHMO_01504 2.5e-269 S Putative peptidoglycan binding domain
ONKNFHMO_01507 1.3e-28 2.7.13.3 T GHKL domain
ONKNFHMO_01508 5e-75 osmC O OsmC-like protein
ONKNFHMO_01509 3.2e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ONKNFHMO_01510 1.5e-222 patA 2.6.1.1 E Aminotransferase
ONKNFHMO_01511 2.7e-32
ONKNFHMO_01512 0.0 clpL O associated with various cellular activities
ONKNFHMO_01514 2.3e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
ONKNFHMO_01515 2.4e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ONKNFHMO_01516 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
ONKNFHMO_01517 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
ONKNFHMO_01518 7.1e-175 malR K Transcriptional regulator, LacI family
ONKNFHMO_01519 2.1e-216 phbA 2.3.1.9 I Belongs to the thiolase family
ONKNFHMO_01520 8.1e-257 malT G Major Facilitator
ONKNFHMO_01521 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
ONKNFHMO_01522 1.9e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
ONKNFHMO_01523 3e-72
ONKNFHMO_01524 8.2e-87 2.7.6.5 T Region found in RelA / SpoT proteins
ONKNFHMO_01525 1.9e-118 K response regulator
ONKNFHMO_01526 2.4e-226 sptS 2.7.13.3 T Histidine kinase
ONKNFHMO_01527 1.3e-218 yfeO P Voltage gated chloride channel
ONKNFHMO_01528 1.1e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ONKNFHMO_01529 3e-71 M repeat protein
ONKNFHMO_01530 3e-27
ONKNFHMO_01531 5.4e-178 M Glycosyltransferase like family 2
ONKNFHMO_01532 1.6e-238 L Integrase core domain
ONKNFHMO_01533 1.2e-132 O Bacterial dnaA protein
ONKNFHMO_01536 5.3e-08 L DnaD domain protein
ONKNFHMO_01538 4.8e-72
ONKNFHMO_01540 2.1e-66
ONKNFHMO_01541 2.8e-44 L transposase and inactivated derivatives, IS30 family
ONKNFHMO_01542 5.6e-126 L PFAM Integrase catalytic region
ONKNFHMO_01543 7.4e-177 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ONKNFHMO_01544 1.1e-59 hol S COG5546 Small integral membrane protein
ONKNFHMO_01545 4.5e-36
ONKNFHMO_01547 2.1e-67 ywiB S Domain of unknown function (DUF1934)
ONKNFHMO_01548 1.5e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ONKNFHMO_01549 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ONKNFHMO_01550 2.9e-154 EG EamA-like transporter family
ONKNFHMO_01551 2.5e-118 L Integrase
ONKNFHMO_01552 1.7e-159 rssA S Phospholipase, patatin family
ONKNFHMO_01553 1e-157 3.2.1.96, 3.5.1.28 GH73 M repeat protein
ONKNFHMO_01554 5e-167 I alpha/beta hydrolase fold
ONKNFHMO_01555 2.3e-116 frnE Q DSBA-like thioredoxin domain
ONKNFHMO_01556 3.6e-55
ONKNFHMO_01560 8.2e-32 S GDSL-like Lipase/Acylhydrolase
ONKNFHMO_01561 2.8e-210
ONKNFHMO_01562 0.0 helD 3.6.4.12 L DNA helicase
ONKNFHMO_01563 3.6e-117 dedA S SNARE associated Golgi protein
ONKNFHMO_01564 5e-127 3.1.3.73 G phosphoglycerate mutase
ONKNFHMO_01565 1.3e-235 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ONKNFHMO_01566 6.6e-35 S Transglycosylase associated protein
ONKNFHMO_01568 1.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ONKNFHMO_01569 9.5e-239 V domain protein
ONKNFHMO_01570 1.6e-94 K Transcriptional regulator (TetR family)
ONKNFHMO_01571 3.4e-39 pspC KT positive regulation of macromolecule biosynthetic process
ONKNFHMO_01572 2e-152
ONKNFHMO_01573 3.1e-17 3.2.1.14 GH18
ONKNFHMO_01574 1.5e-82 zur P Belongs to the Fur family
ONKNFHMO_01575 5.2e-104 gmk2 2.7.4.8 F Guanylate kinase
ONKNFHMO_01576 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
ONKNFHMO_01577 1.1e-256 yfnA E Amino Acid
ONKNFHMO_01578 3.9e-232 EGP Sugar (and other) transporter
ONKNFHMO_01579 1e-232
ONKNFHMO_01580 2.3e-209 potD P ABC transporter
ONKNFHMO_01581 4.9e-140 potC P ABC transporter permease
ONKNFHMO_01582 4.5e-146 potB P ABC transporter permease
ONKNFHMO_01583 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
ONKNFHMO_01584 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
ONKNFHMO_01585 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
ONKNFHMO_01586 0.0 pacL 3.6.3.8 P P-type ATPase
ONKNFHMO_01587 2.6e-85 dps P Belongs to the Dps family
ONKNFHMO_01588 3e-254 yagE E amino acid
ONKNFHMO_01589 2.5e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant
ONKNFHMO_01590 5.7e-30 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ONKNFHMO_01591 2e-25 L Helix-turn-helix domain
ONKNFHMO_01592 5.1e-87 L Helix-turn-helix domain
ONKNFHMO_01593 1e-127 L hmm pf00665
ONKNFHMO_01594 4.7e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
ONKNFHMO_01595 2.1e-182 iunH2 3.2.2.1 F nucleoside hydrolase
ONKNFHMO_01596 2.5e-138 IQ KR domain
ONKNFHMO_01597 6.6e-134 S membrane transporter protein
ONKNFHMO_01598 1.9e-98 S ABC-type cobalt transport system, permease component
ONKNFHMO_01599 1.6e-260 cbiO1 S ABC transporter, ATP-binding protein
ONKNFHMO_01600 2.6e-115 P Cobalt transport protein
ONKNFHMO_01601 1.6e-52 yvlA
ONKNFHMO_01602 0.0 yjcE P Sodium proton antiporter
ONKNFHMO_01603 2.2e-52 ypaA S Protein of unknown function (DUF1304)
ONKNFHMO_01604 5.9e-168 D Alpha beta
ONKNFHMO_01605 1e-72 K Transcriptional regulator
ONKNFHMO_01606 2.6e-163
ONKNFHMO_01607 8.8e-184 1.6.5.5 C Zinc-binding dehydrogenase
ONKNFHMO_01608 3.5e-258 G PTS system Galactitol-specific IIC component
ONKNFHMO_01609 8.2e-213 EGP Major facilitator Superfamily
ONKNFHMO_01610 1.5e-137 V ABC transporter
ONKNFHMO_01611 4.5e-121
ONKNFHMO_01612 5.2e-14
ONKNFHMO_01613 1.9e-63
ONKNFHMO_01614 3.9e-195 lplA 6.3.1.20 H Lipoate-protein ligase
ONKNFHMO_01615 5.1e-81 uspA T universal stress protein
ONKNFHMO_01616 0.0 tetP J elongation factor G
ONKNFHMO_01617 2.1e-168 GK ROK family
ONKNFHMO_01618 7.2e-245 brnQ U Component of the transport system for branched-chain amino acids
ONKNFHMO_01619 1.3e-81 tlpA2 L Transposase IS200 like
ONKNFHMO_01620 4.9e-240 L transposase, IS605 OrfB family
ONKNFHMO_01621 7e-141 aroD S Serine hydrolase (FSH1)
ONKNFHMO_01622 7.2e-245 yagE E amino acid
ONKNFHMO_01623 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
ONKNFHMO_01624 4.3e-135 gntR K UbiC transcription regulator-associated domain protein
ONKNFHMO_01625 4.2e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ONKNFHMO_01626 1.2e-285 pipD E Dipeptidase
ONKNFHMO_01627 0.0 yfiC V ABC transporter
ONKNFHMO_01628 4.8e-310 lmrA V ABC transporter, ATP-binding protein
ONKNFHMO_01629 2.9e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ONKNFHMO_01630 1.2e-81 S ECF transporter, substrate-specific component
ONKNFHMO_01631 2.5e-62 S Domain of unknown function (DUF4430)
ONKNFHMO_01632 5.9e-194 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
ONKNFHMO_01633 7.3e-132 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
ONKNFHMO_01634 5.4e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
ONKNFHMO_01635 4.8e-137 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ONKNFHMO_01636 1.6e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
ONKNFHMO_01637 3.4e-252 hemL 5.4.3.8 H Aminotransferase class-III
ONKNFHMO_01638 2.4e-181 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
ONKNFHMO_01639 2.3e-170 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
ONKNFHMO_01640 1.4e-237 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ONKNFHMO_01641 3.2e-80 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
ONKNFHMO_01642 3.3e-283 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
ONKNFHMO_01643 2e-149 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
ONKNFHMO_01644 4.4e-118 cbiQ P Cobalt transport protein
ONKNFHMO_01645 8.7e-53 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
ONKNFHMO_01646 2.4e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
ONKNFHMO_01647 6e-126 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
ONKNFHMO_01648 2.3e-147 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
ONKNFHMO_01649 3e-262 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
ONKNFHMO_01650 2.5e-138 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
ONKNFHMO_01651 5.7e-132 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
ONKNFHMO_01652 8.2e-196 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
ONKNFHMO_01653 4.8e-137 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
ONKNFHMO_01654 4.9e-99 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
ONKNFHMO_01655 1e-110 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
ONKNFHMO_01656 1.6e-208 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ONKNFHMO_01657 9.2e-124 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
ONKNFHMO_01658 5.7e-180 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ONKNFHMO_01659 4.1e-264 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
ONKNFHMO_01660 1.5e-208 cobD 4.1.1.81 E Aminotransferase class I and II
ONKNFHMO_01662 2.3e-65 XK27_01125 L PFAM IS66 Orf2 family protein
ONKNFHMO_01663 1.8e-289 L Transposase IS66 family
ONKNFHMO_01664 3.2e-119 S dextransucrase activity
ONKNFHMO_01665 7.7e-35
ONKNFHMO_01666 4.4e-55 S Mazg nucleotide pyrophosphohydrolase
ONKNFHMO_01667 8.8e-161 xth 3.1.11.2 L exodeoxyribonuclease III
ONKNFHMO_01668 2.5e-230 L transposase, IS605 OrfB family
ONKNFHMO_01669 9.6e-61 L PFAM transposase IS200-family protein
ONKNFHMO_01670 5.8e-106 L Helix-turn-helix domain
ONKNFHMO_01671 7.8e-157
ONKNFHMO_01673 1.7e-237 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ONKNFHMO_01674 4.9e-87
ONKNFHMO_01675 4.8e-96 K Acetyltransferase (GNAT) domain
ONKNFHMO_01676 1.2e-160 S Alpha beta hydrolase
ONKNFHMO_01677 3.1e-161 gspA M family 8
ONKNFHMO_01678 6e-120 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
ONKNFHMO_01679 9.4e-94
ONKNFHMO_01680 1.7e-162 degV S EDD domain protein, DegV family
ONKNFHMO_01681 0.0 FbpA K Fibronectin-binding protein
ONKNFHMO_01682 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ONKNFHMO_01683 1.5e-208 carA 6.3.5.5 F Belongs to the CarA family
ONKNFHMO_01684 4.8e-176 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ONKNFHMO_01685 1.3e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ONKNFHMO_01686 1.5e-65 esbA S Family of unknown function (DUF5322)
ONKNFHMO_01687 6.9e-71 rnhA 3.1.26.4 L Ribonuclease HI
ONKNFHMO_01688 1.2e-232 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
ONKNFHMO_01689 7.7e-85 F Belongs to the NrdI family
ONKNFHMO_01690 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ONKNFHMO_01691 1.6e-105 ypsA S Belongs to the UPF0398 family
ONKNFHMO_01692 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ONKNFHMO_01693 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
ONKNFHMO_01694 1.4e-162 EG EamA-like transporter family
ONKNFHMO_01695 5.1e-125 dnaD L DnaD domain protein
ONKNFHMO_01696 1.8e-87 ypmB S Protein conserved in bacteria
ONKNFHMO_01697 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
ONKNFHMO_01698 2.1e-174 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
ONKNFHMO_01699 4.6e-177 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
ONKNFHMO_01700 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
ONKNFHMO_01701 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ONKNFHMO_01702 1.9e-89 S Protein of unknown function (DUF1440)
ONKNFHMO_01703 0.0 rafA 3.2.1.22 G alpha-galactosidase
ONKNFHMO_01704 6.3e-193 galR K Periplasmic binding protein-like domain
ONKNFHMO_01705 1.4e-80 scrK 2.7.1.2, 2.7.1.4 GK ROK family
ONKNFHMO_01706 2.5e-80 scrK 2.7.1.2, 2.7.1.4 GK ROK family
ONKNFHMO_01707 6.4e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ONKNFHMO_01708 2.6e-124 lrgB M LrgB-like family
ONKNFHMO_01709 1.9e-66 lrgA S LrgA family
ONKNFHMO_01710 1.1e-130 lytT K response regulator receiver
ONKNFHMO_01711 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
ONKNFHMO_01712 3.4e-147 f42a O Band 7 protein
ONKNFHMO_01713 2e-266 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
ONKNFHMO_01714 2.9e-156 yitU 3.1.3.104 S hydrolase
ONKNFHMO_01715 3.2e-39 S Cytochrome B5
ONKNFHMO_01716 1.2e-117 nreC K PFAM regulatory protein LuxR
ONKNFHMO_01717 1.5e-161 hipB K Helix-turn-helix
ONKNFHMO_01718 2.8e-57 yitW S Iron-sulfur cluster assembly protein
ONKNFHMO_01719 4.2e-272 sufB O assembly protein SufB
ONKNFHMO_01720 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
ONKNFHMO_01721 1.6e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ONKNFHMO_01722 5.4e-242 sufD O FeS assembly protein SufD
ONKNFHMO_01723 6.5e-145 sufC O FeS assembly ATPase SufC
ONKNFHMO_01724 1.2e-31 feoA P FeoA domain
ONKNFHMO_01725 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
ONKNFHMO_01726 1.6e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
ONKNFHMO_01727 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ONKNFHMO_01728 1.6e-64 ydiI Q Thioesterase superfamily
ONKNFHMO_01729 2.4e-109 yvrI K sigma factor activity
ONKNFHMO_01730 5e-202 G Transporter, major facilitator family protein
ONKNFHMO_01731 0.0 S Bacterial membrane protein YfhO
ONKNFHMO_01732 3.9e-104 T Ion transport 2 domain protein
ONKNFHMO_01733 4.7e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
ONKNFHMO_01734 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
ONKNFHMO_01735 4.5e-106 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
ONKNFHMO_01736 1.8e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ONKNFHMO_01737 5.1e-181 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
ONKNFHMO_01739 0.0 L PLD-like domain
ONKNFHMO_01740 4.3e-36 higA K addiction module antidote protein HigA
ONKNFHMO_01741 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
ONKNFHMO_01742 2.3e-180 3.1.21.3 V Type I restriction modification DNA specificity domain
ONKNFHMO_01743 1.5e-180 xerC L Belongs to the 'phage' integrase family
ONKNFHMO_01744 6.8e-113 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
ONKNFHMO_01745 9.5e-101 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
ONKNFHMO_01746 2.1e-301 2.1.1.72 V type I restriction-modification system
ONKNFHMO_01747 2.8e-58 yhaI S Protein of unknown function (DUF805)
ONKNFHMO_01748 2.2e-44
ONKNFHMO_01749 0.0 nylA 3.5.1.4 J Belongs to the amidase family
ONKNFHMO_01750 2.4e-22
ONKNFHMO_01751 6.5e-41
ONKNFHMO_01752 1.7e-96 K Acetyltransferase (GNAT) domain
ONKNFHMO_01753 5.3e-297 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ONKNFHMO_01754 1e-15 gntT EG Gluconate
ONKNFHMO_01755 8.8e-178 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ONKNFHMO_01756 2.9e-81 S Bacteriophage holin family
ONKNFHMO_01758 1.6e-66 XK27_01125 L PFAM IS66 Orf2 family protein
ONKNFHMO_01761 3.8e-08 M domain protein
ONKNFHMO_01764 3.3e-85 L PFAM transposase IS200-family protein
ONKNFHMO_01765 7.3e-85 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
ONKNFHMO_01766 1.3e-276 lysP E amino acid
ONKNFHMO_01767 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
ONKNFHMO_01768 2.7e-120 lssY 3.6.1.27 I phosphatase
ONKNFHMO_01769 7.2e-83 S Threonine/Serine exporter, ThrE
ONKNFHMO_01770 2.1e-132 thrE S Putative threonine/serine exporter
ONKNFHMO_01771 3.5e-31 cspC K Cold shock protein
ONKNFHMO_01772 4.8e-125 sirR K iron dependent repressor
ONKNFHMO_01773 5.9e-166 czcD P cation diffusion facilitator family transporter
ONKNFHMO_01774 7.7e-118 S membrane
ONKNFHMO_01775 1.3e-109 S VIT family
ONKNFHMO_01776 5.5e-83 usp1 T Belongs to the universal stress protein A family
ONKNFHMO_01777 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ONKNFHMO_01778 1.5e-152 glnH ET ABC transporter
ONKNFHMO_01779 2.4e-110 gluC P ABC transporter permease
ONKNFHMO_01780 3.6e-109 glnP P ABC transporter permease
ONKNFHMO_01781 8.3e-221 S CAAX protease self-immunity
ONKNFHMO_01782 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ONKNFHMO_01783 2.9e-57
ONKNFHMO_01784 2.6e-74 merR K MerR HTH family regulatory protein
ONKNFHMO_01785 7.2e-270 lmrB EGP Major facilitator Superfamily
ONKNFHMO_01786 5.8e-124 S Domain of unknown function (DUF4811)
ONKNFHMO_01787 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
ONKNFHMO_01789 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ONKNFHMO_01790 1.5e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
ONKNFHMO_01791 5.3e-189 I Alpha beta
ONKNFHMO_01792 1.9e-281 emrY EGP Major facilitator Superfamily
ONKNFHMO_01793 4.5e-120 ung2 3.2.2.27 L Uracil-DNA glycosylase
ONKNFHMO_01794 9.4e-253 yjjP S Putative threonine/serine exporter
ONKNFHMO_01795 8e-160 mleR K LysR family
ONKNFHMO_01796 1.2e-253 yflS P Sodium:sulfate symporter transmembrane region
ONKNFHMO_01797 5.6e-269 frdC 1.3.5.4 C FAD binding domain
ONKNFHMO_01798 2.1e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ONKNFHMO_01799 2e-310 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
ONKNFHMO_01800 2.5e-161 mleR K LysR family
ONKNFHMO_01801 7.8e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ONKNFHMO_01802 2.7e-207 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
ONKNFHMO_01803 2.3e-300 L PFAM plasmid pRiA4b ORF-3 family protein
ONKNFHMO_01804 2e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
ONKNFHMO_01805 2e-22
ONKNFHMO_01806 3.1e-203 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
ONKNFHMO_01807 3e-75
ONKNFHMO_01808 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ONKNFHMO_01809 1.8e-131 ponA V Beta-lactamase enzyme family
ONKNFHMO_01810 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
ONKNFHMO_01811 4.4e-217 uhpT EGP Major facilitator Superfamily
ONKNFHMO_01812 6.4e-262 ytjP 3.5.1.18 E Dipeptidase
ONKNFHMO_01813 1.5e-275 arcD S C4-dicarboxylate anaerobic carrier
ONKNFHMO_01814 3e-181 yfeX P Peroxidase
ONKNFHMO_01815 6.1e-102 lsa S ABC transporter
ONKNFHMO_01816 3.2e-164 lsa S ABC transporter
ONKNFHMO_01817 4.5e-137 I alpha/beta hydrolase fold
ONKNFHMO_01818 3.6e-180 MA20_14895 S Conserved hypothetical protein 698
ONKNFHMO_01819 7.6e-97 S NADPH-dependent FMN reductase
ONKNFHMO_01820 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ONKNFHMO_01821 3e-181 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
ONKNFHMO_01822 1.6e-233 mntH P H( )-stimulated, divalent metal cation uptake system
ONKNFHMO_01823 2e-83 Q Methyltransferase
ONKNFHMO_01824 1.4e-116 ktrA P domain protein
ONKNFHMO_01825 8.1e-241 ktrB P Potassium uptake protein
ONKNFHMO_01826 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
ONKNFHMO_01827 3.5e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
ONKNFHMO_01828 6.9e-225 G Glycosyl hydrolases family 8
ONKNFHMO_01829 4.8e-246 ydaM M Glycosyl transferase
ONKNFHMO_01830 5.2e-148
ONKNFHMO_01831 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
ONKNFHMO_01832 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ONKNFHMO_01833 2.6e-155 pstA P Phosphate transport system permease protein PstA
ONKNFHMO_01834 1.1e-153 pstC P probably responsible for the translocation of the substrate across the membrane
ONKNFHMO_01835 4.6e-160 pstS P Phosphate
ONKNFHMO_01836 1.6e-134 K Transcriptional regulatory protein, C-terminal domain protein
ONKNFHMO_01837 9e-30 A chlorophyll binding
ONKNFHMO_01838 1.5e-76
ONKNFHMO_01841 1.7e-156 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
ONKNFHMO_01842 2.4e-272 ywfO S HD domain protein
ONKNFHMO_01843 4.1e-150 yxeH S hydrolase
ONKNFHMO_01844 5.6e-50
ONKNFHMO_01845 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ONKNFHMO_01846 1.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ONKNFHMO_01847 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
ONKNFHMO_01848 3.2e-128 znuB U ABC 3 transport family
ONKNFHMO_01849 7.7e-123 fhuC P ABC transporter
ONKNFHMO_01850 1.3e-170 znuA P Belongs to the bacterial solute-binding protein 9 family
ONKNFHMO_01851 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ONKNFHMO_01852 6.8e-37 veg S Biofilm formation stimulator VEG
ONKNFHMO_01853 3.8e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ONKNFHMO_01854 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ONKNFHMO_01855 1.5e-157 tatD L hydrolase, TatD family
ONKNFHMO_01856 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ONKNFHMO_01857 7.4e-163 yunF F Protein of unknown function DUF72
ONKNFHMO_01859 4.2e-132 cobB K SIR2 family
ONKNFHMO_01860 1.1e-178
ONKNFHMO_01861 1.3e-232 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
ONKNFHMO_01862 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ONKNFHMO_01863 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
ONKNFHMO_01864 1.3e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
ONKNFHMO_01865 1.7e-81 ndk 2.7.4.6 F Belongs to the NDK family
ONKNFHMO_01866 0.0 helD 3.6.4.12 L DNA helicase
ONKNFHMO_01867 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ONKNFHMO_01869 6.3e-257 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ONKNFHMO_01870 1.2e-266 yfnA E amino acid
ONKNFHMO_01871 4.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ONKNFHMO_01872 8.6e-44 1.3.5.4 S FMN binding
ONKNFHMO_01873 1.7e-221 norA EGP Major facilitator Superfamily
ONKNFHMO_01874 3.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
ONKNFHMO_01875 3.9e-156 metQ1 P Belongs to the nlpA lipoprotein family
ONKNFHMO_01876 1.5e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ONKNFHMO_01877 3.1e-103 metI P ABC transporter permease
ONKNFHMO_01878 4.4e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ONKNFHMO_01879 4.9e-254 clcA P chloride
ONKNFHMO_01880 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ONKNFHMO_01881 5.8e-104 proW P ABC transporter, permease protein
ONKNFHMO_01882 1.3e-142 proV E ABC transporter, ATP-binding protein
ONKNFHMO_01883 9.7e-110 proWZ P ABC transporter permease
ONKNFHMO_01884 7e-164 proX M ABC transporter, substrate-binding protein, QAT family
ONKNFHMO_01885 2e-74 K Transcriptional regulator
ONKNFHMO_01886 3.8e-159 1.6.5.2 GM NAD(P)H-binding
ONKNFHMO_01888 3.1e-228 5.4.2.7 G Metalloenzyme superfamily
ONKNFHMO_01889 0.0 cadA P P-type ATPase
ONKNFHMO_01890 6.4e-131 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
ONKNFHMO_01891 4.4e-129
ONKNFHMO_01892 3.3e-55 S Sugar efflux transporter for intercellular exchange
ONKNFHMO_01893 1.8e-256 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
ONKNFHMO_01895 0.0 L Helicase C-terminal domain protein
ONKNFHMO_01896 1.5e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
ONKNFHMO_01897 2.1e-182 S Aldo keto reductase
ONKNFHMO_01899 2.9e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ONKNFHMO_01900 2e-62 psiE S Phosphate-starvation-inducible E
ONKNFHMO_01901 5.5e-103 ydeN S Serine hydrolase
ONKNFHMO_01903 1.9e-50 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ONKNFHMO_01904 1.7e-108 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ONKNFHMO_01905 2.3e-257 nhaC C Na H antiporter NhaC
ONKNFHMO_01906 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
ONKNFHMO_01907 5.7e-115 ywnB S NAD(P)H-binding
ONKNFHMO_01908 4.4e-38
ONKNFHMO_01909 2.6e-132 IQ Dehydrogenase reductase
ONKNFHMO_01910 3.3e-242 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
ONKNFHMO_01911 5.6e-39 hxlR K regulation of RNA biosynthetic process
ONKNFHMO_01912 7.9e-168 G Belongs to the carbohydrate kinase PfkB family
ONKNFHMO_01913 1.8e-256 F Belongs to the purine-cytosine permease (2.A.39) family
ONKNFHMO_01914 1.1e-208 yegU O ADP-ribosylglycohydrolase
ONKNFHMO_01915 2.7e-105 pncA Q Isochorismatase family
ONKNFHMO_01916 2.7e-274 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ONKNFHMO_01917 1.9e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
ONKNFHMO_01922 5.5e-110 dedA S SNARE-like domain protein
ONKNFHMO_01923 2.8e-114 S Protein of unknown function (DUF1461)
ONKNFHMO_01924 2.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ONKNFHMO_01925 4.4e-100 yutD S Protein of unknown function (DUF1027)
ONKNFHMO_01926 8.8e-118 S Calcineurin-like phosphoesterase
ONKNFHMO_01927 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ONKNFHMO_01928 5.9e-146 ytxK 2.1.1.72 L N-6 DNA Methylase
ONKNFHMO_01930 3.6e-73
ONKNFHMO_01931 4.8e-45
ONKNFHMO_01932 1.5e-79 NU general secretion pathway protein
ONKNFHMO_01933 7.1e-47 comGC U competence protein ComGC
ONKNFHMO_01934 1.2e-186 comGB NU type II secretion system
ONKNFHMO_01935 7.9e-185 comGA NU Type II IV secretion system protein
ONKNFHMO_01936 3.5e-132 yebC K Transcriptional regulatory protein
ONKNFHMO_01937 1.8e-137
ONKNFHMO_01938 4.5e-183 ccpA K catabolite control protein A
ONKNFHMO_01939 1.2e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ONKNFHMO_01940 1.8e-14
ONKNFHMO_01941 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ONKNFHMO_01942 2.1e-149 ykuT M mechanosensitive ion channel
ONKNFHMO_01943 1.2e-154 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
ONKNFHMO_01944 2.7e-76 ykuL S (CBS) domain
ONKNFHMO_01945 2.1e-96 S Phosphoesterase
ONKNFHMO_01946 1.8e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ONKNFHMO_01947 1.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ONKNFHMO_01948 4.1e-98 yslB S Protein of unknown function (DUF2507)
ONKNFHMO_01949 6.1e-54 trxA O Belongs to the thioredoxin family
ONKNFHMO_01950 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ONKNFHMO_01951 1.6e-86 cvpA S Colicin V production protein
ONKNFHMO_01952 6.1e-48 yrzB S Belongs to the UPF0473 family
ONKNFHMO_01953 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ONKNFHMO_01954 4.1e-43 yrzL S Belongs to the UPF0297 family
ONKNFHMO_01955 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ONKNFHMO_01956 1.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ONKNFHMO_01957 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
ONKNFHMO_01958 1.5e-29 yajC U Preprotein translocase
ONKNFHMO_01959 2.2e-204 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ONKNFHMO_01960 1.2e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ONKNFHMO_01961 1.8e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ONKNFHMO_01962 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ONKNFHMO_01963 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ONKNFHMO_01964 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
ONKNFHMO_01965 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ONKNFHMO_01966 3.4e-233 cinA 3.5.1.42 S Belongs to the CinA family
ONKNFHMO_01967 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ONKNFHMO_01968 1.9e-141 ymfM S Helix-turn-helix domain
ONKNFHMO_01969 2.4e-250 ymfH S Peptidase M16
ONKNFHMO_01970 4.2e-231 ymfF S Peptidase M16 inactive domain protein
ONKNFHMO_01971 1.5e-160 aatB ET ABC transporter substrate-binding protein
ONKNFHMO_01972 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ONKNFHMO_01973 3.2e-102 glnP P ABC transporter permease
ONKNFHMO_01974 8.7e-93 mreD M rod shape-determining protein MreD
ONKNFHMO_01975 5.9e-152 mreC M Involved in formation and maintenance of cell shape
ONKNFHMO_01976 1.7e-179 mreB D cell shape determining protein MreB
ONKNFHMO_01977 1.2e-122 radC L DNA repair protein
ONKNFHMO_01978 9.4e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ONKNFHMO_01979 4.8e-232 ndh 1.6.99.3 C NADH dehydrogenase
ONKNFHMO_01980 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ONKNFHMO_01981 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
ONKNFHMO_01982 3.3e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
ONKNFHMO_01983 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
ONKNFHMO_01984 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ONKNFHMO_01985 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ONKNFHMO_01986 7e-217 iscS2 2.8.1.7 E Aminotransferase class V
ONKNFHMO_01987 9e-253 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ONKNFHMO_01988 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ONKNFHMO_01989 1.1e-235 pbuG S permease

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)