ORF_ID e_value Gene_name EC_number CAZy COGs Description
PIKHPIBO_00001 2.3e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PIKHPIBO_00002 3.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PIKHPIBO_00003 2.4e-33 yaaA S S4 domain
PIKHPIBO_00004 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PIKHPIBO_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
PIKHPIBO_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIKHPIBO_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIKHPIBO_00008 2.2e-38 S COG NOG14552 non supervised orthologous group
PIKHPIBO_00011 6.7e-184 yaaC S YaaC-like Protein
PIKHPIBO_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PIKHPIBO_00013 1.2e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PIKHPIBO_00014 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PIKHPIBO_00015 1.6e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PIKHPIBO_00016 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PIKHPIBO_00017 1.7e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PIKHPIBO_00018 1.3e-09
PIKHPIBO_00019 5.4e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
PIKHPIBO_00020 6.1e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
PIKHPIBO_00021 1e-208 yaaH M Glycoside Hydrolase Family
PIKHPIBO_00022 3.7e-99 yaaI Q COG1335 Amidases related to nicotinamidase
PIKHPIBO_00023 1e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PIKHPIBO_00024 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIKHPIBO_00025 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PIKHPIBO_00026 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PIKHPIBO_00027 3.6e-32 yaaL S Protein of unknown function (DUF2508)
PIKHPIBO_00028 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
PIKHPIBO_00029 3.4e-39 S COG NOG14552 non supervised orthologous group
PIKHPIBO_00032 2.2e-30 csfB S Inhibitor of sigma-G Gin
PIKHPIBO_00033 1e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PIKHPIBO_00034 1.3e-188 yaaN P Belongs to the TelA family
PIKHPIBO_00035 5.6e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
PIKHPIBO_00036 4.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PIKHPIBO_00037 7.5e-55 yaaQ S protein conserved in bacteria
PIKHPIBO_00038 3.4e-71 yaaR S protein conserved in bacteria
PIKHPIBO_00039 1.3e-182 holB 2.7.7.7 L DNA polymerase III
PIKHPIBO_00040 8.8e-145 yaaT S stage 0 sporulation protein
PIKHPIBO_00041 7.7e-37 yabA L Involved in initiation control of chromosome replication
PIKHPIBO_00042 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
PIKHPIBO_00043 4.7e-48 yazA L endonuclease containing a URI domain
PIKHPIBO_00044 8.4e-162 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PIKHPIBO_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
PIKHPIBO_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PIKHPIBO_00047 1.5e-143 tatD L hydrolase, TatD
PIKHPIBO_00048 1.8e-232 rpfB GH23 T protein conserved in bacteria
PIKHPIBO_00049 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PIKHPIBO_00050 4.3e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PIKHPIBO_00051 8.4e-146 yabG S peptidase
PIKHPIBO_00052 7.8e-39 veg S protein conserved in bacteria
PIKHPIBO_00053 2.9e-27 sspF S DNA topological change
PIKHPIBO_00054 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PIKHPIBO_00055 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PIKHPIBO_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
PIKHPIBO_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PIKHPIBO_00058 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PIKHPIBO_00059 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIKHPIBO_00060 1.7e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PIKHPIBO_00061 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PIKHPIBO_00062 3.7e-40 yabK S Peptide ABC transporter permease
PIKHPIBO_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PIKHPIBO_00064 6.2e-91 spoVT K stage V sporulation protein
PIKHPIBO_00065 4.5e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIKHPIBO_00066 1.1e-275 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PIKHPIBO_00067 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PIKHPIBO_00068 1.9e-49 yabP S Sporulation protein YabP
PIKHPIBO_00069 1.4e-102 yabQ S spore cortex biosynthesis protein
PIKHPIBO_00070 1.8e-52 divIC D Septum formation initiator
PIKHPIBO_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
PIKHPIBO_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
PIKHPIBO_00075 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
PIKHPIBO_00076 2e-183 KLT serine threonine protein kinase
PIKHPIBO_00077 7.2e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PIKHPIBO_00078 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PIKHPIBO_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PIKHPIBO_00080 1.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PIKHPIBO_00081 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PIKHPIBO_00082 4.5e-155 yacD 5.2.1.8 O peptidyl-prolyl isomerase
PIKHPIBO_00083 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PIKHPIBO_00084 1.2e-269 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PIKHPIBO_00085 1.2e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
PIKHPIBO_00086 1.9e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
PIKHPIBO_00087 3.6e-157 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PIKHPIBO_00088 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PIKHPIBO_00089 1.9e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PIKHPIBO_00090 4.5e-29 yazB K transcriptional
PIKHPIBO_00091 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PIKHPIBO_00092 4.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PIKHPIBO_00093 2.2e-38 S COG NOG14552 non supervised orthologous group
PIKHPIBO_00095 1.3e-07
PIKHPIBO_00098 2e-08
PIKHPIBO_00103 2.2e-38 S COG NOG14552 non supervised orthologous group
PIKHPIBO_00104 7.5e-77 ctsR K Belongs to the CtsR family
PIKHPIBO_00105 2.1e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
PIKHPIBO_00106 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PIKHPIBO_00107 0.0 clpC O Belongs to the ClpA ClpB family
PIKHPIBO_00108 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PIKHPIBO_00109 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PIKHPIBO_00110 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
PIKHPIBO_00111 4.7e-123 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PIKHPIBO_00112 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PIKHPIBO_00113 2.2e-276 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PIKHPIBO_00114 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
PIKHPIBO_00115 1.8e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PIKHPIBO_00116 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PIKHPIBO_00117 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIKHPIBO_00118 4.2e-89 yacP S RNA-binding protein containing a PIN domain
PIKHPIBO_00119 8.9e-116 sigH K Belongs to the sigma-70 factor family
PIKHPIBO_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PIKHPIBO_00121 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
PIKHPIBO_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PIKHPIBO_00123 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PIKHPIBO_00124 2.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PIKHPIBO_00125 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PIKHPIBO_00126 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
PIKHPIBO_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIKHPIBO_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIKHPIBO_00129 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
PIKHPIBO_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PIKHPIBO_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PIKHPIBO_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PIKHPIBO_00133 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PIKHPIBO_00134 4.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
PIKHPIBO_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PIKHPIBO_00136 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PIKHPIBO_00137 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
PIKHPIBO_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PIKHPIBO_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PIKHPIBO_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PIKHPIBO_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PIKHPIBO_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PIKHPIBO_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PIKHPIBO_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
PIKHPIBO_00145 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PIKHPIBO_00146 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PIKHPIBO_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PIKHPIBO_00148 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PIKHPIBO_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIKHPIBO_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PIKHPIBO_00151 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PIKHPIBO_00152 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PIKHPIBO_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PIKHPIBO_00154 1.9e-23 rpmD J Ribosomal protein L30
PIKHPIBO_00155 4.1e-72 rplO J binds to the 23S rRNA
PIKHPIBO_00156 1.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PIKHPIBO_00157 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PIKHPIBO_00158 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
PIKHPIBO_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PIKHPIBO_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PIKHPIBO_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PIKHPIBO_00162 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PIKHPIBO_00163 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIKHPIBO_00164 4.7e-58 rplQ J Ribosomal protein L17
PIKHPIBO_00165 8.7e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIKHPIBO_00166 2.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIKHPIBO_00167 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIKHPIBO_00168 2.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PIKHPIBO_00169 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PIKHPIBO_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
PIKHPIBO_00171 8.2e-145 ybaJ Q Methyltransferase domain
PIKHPIBO_00172 3e-81 yizA S Damage-inducible protein DinB
PIKHPIBO_00173 1.7e-78 ybaK S Protein of unknown function (DUF2521)
PIKHPIBO_00174 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PIKHPIBO_00175 1.3e-196 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PIKHPIBO_00176 1.7e-75 gerD
PIKHPIBO_00177 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
PIKHPIBO_00178 1.1e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
PIKHPIBO_00179 3.4e-39 S COG NOG14552 non supervised orthologous group
PIKHPIBO_00182 1.6e-08
PIKHPIBO_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
PIKHPIBO_00186 1.9e-217 glcP G Major Facilitator Superfamily
PIKHPIBO_00187 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PIKHPIBO_00188 2.5e-180 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
PIKHPIBO_00189 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
PIKHPIBO_00190 2.7e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
PIKHPIBO_00191 2.2e-174 ybaS 1.1.1.58 S Na -dependent transporter
PIKHPIBO_00192 2.4e-112 ybbA S Putative esterase
PIKHPIBO_00193 2.3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIKHPIBO_00194 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIKHPIBO_00195 2e-172 feuA P Iron-uptake system-binding protein
PIKHPIBO_00196 7e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
PIKHPIBO_00197 1.5e-236 ybbC 3.2.1.52 S protein conserved in bacteria
PIKHPIBO_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
PIKHPIBO_00199 3.1e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
PIKHPIBO_00200 1.5e-237 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PIKHPIBO_00201 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PIKHPIBO_00202 9.1e-86 ybbJ J acetyltransferase
PIKHPIBO_00203 8.7e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
PIKHPIBO_00209 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
PIKHPIBO_00210 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PIKHPIBO_00211 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PIKHPIBO_00212 4.4e-224 ybbR S protein conserved in bacteria
PIKHPIBO_00213 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PIKHPIBO_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PIKHPIBO_00215 3.8e-154 V ATPases associated with a variety of cellular activities
PIKHPIBO_00216 1.1e-105 S ABC-2 family transporter protein
PIKHPIBO_00217 5.9e-65 ybdN
PIKHPIBO_00219 4.6e-131 ybdO S Domain of unknown function (DUF4885)
PIKHPIBO_00220 7.3e-163 dkgB S Aldo/keto reductase family
PIKHPIBO_00221 1e-93 yxaC M effector of murein hydrolase
PIKHPIBO_00222 1.2e-51 S LrgA family
PIKHPIBO_00223 4e-72 yxaD K helix_turn_helix multiple antibiotic resistance protein
PIKHPIBO_00225 4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
PIKHPIBO_00226 2.1e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PIKHPIBO_00227 3.1e-201 T COG4585 Signal transduction histidine kinase
PIKHPIBO_00228 1.1e-107 KT LuxR family transcriptional regulator
PIKHPIBO_00229 9.2e-167 V COG1131 ABC-type multidrug transport system, ATPase component
PIKHPIBO_00230 5.8e-206 V COG0842 ABC-type multidrug transport system, permease component
PIKHPIBO_00231 1e-199 V ABC-2 family transporter protein
PIKHPIBO_00232 5.8e-25
PIKHPIBO_00233 4.5e-77 S Domain of unknown function (DUF4879)
PIKHPIBO_00234 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
PIKHPIBO_00235 1e-106 yqeB
PIKHPIBO_00236 9.2e-40 ybyB
PIKHPIBO_00237 9.5e-292 ybeC E amino acid
PIKHPIBO_00238 1.1e-45 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PIKHPIBO_00239 6.1e-54
PIKHPIBO_00240 3.4e-15 S Protein of unknown function (DUF2651)
PIKHPIBO_00241 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PIKHPIBO_00242 1.7e-259 glpT G -transporter
PIKHPIBO_00243 1.3e-16 S Protein of unknown function (DUF2651)
PIKHPIBO_00244 2.5e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
PIKHPIBO_00246 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
PIKHPIBO_00247 7.8e-31
PIKHPIBO_00248 1.2e-82 K Helix-turn-helix XRE-family like proteins
PIKHPIBO_00249 2.1e-199 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
PIKHPIBO_00250 2.3e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PIKHPIBO_00251 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PIKHPIBO_00252 1.9e-86 ybfM S SNARE associated Golgi protein
PIKHPIBO_00253 2.5e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
PIKHPIBO_00254 2.3e-41 ybfN
PIKHPIBO_00255 1.9e-191 yceA S Belongs to the UPF0176 family
PIKHPIBO_00256 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIKHPIBO_00257 1.2e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PIKHPIBO_00258 1.3e-255 mmuP E amino acid
PIKHPIBO_00259 4.3e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
PIKHPIBO_00260 1.3e-257 agcS E Sodium alanine symporter
PIKHPIBO_00261 1.8e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
PIKHPIBO_00262 6.5e-211 phoQ 2.7.13.3 T Histidine kinase
PIKHPIBO_00263 1.9e-172 glnL T Regulator
PIKHPIBO_00265 6e-126 ycbJ S Macrolide 2'-phosphotransferase
PIKHPIBO_00266 5.3e-25 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
PIKHPIBO_00267 5.6e-62 ycbP S Protein of unknown function (DUF2512)
PIKHPIBO_00268 5.3e-77 sleB 3.5.1.28 M Cell wall
PIKHPIBO_00269 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
PIKHPIBO_00270 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PIKHPIBO_00271 4.7e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PIKHPIBO_00272 2.1e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PIKHPIBO_00273 2.7e-205 ycbU E Selenocysteine lyase
PIKHPIBO_00274 4.8e-239 lmrB EGP the major facilitator superfamily
PIKHPIBO_00275 5.9e-100 yxaF K Transcriptional regulator
PIKHPIBO_00276 3.2e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PIKHPIBO_00277 3.7e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
PIKHPIBO_00278 5.4e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
PIKHPIBO_00279 1.8e-170 yccK C Aldo keto reductase
PIKHPIBO_00280 2.3e-176 ycdA S Domain of unknown function (DUF5105)
PIKHPIBO_00281 1.3e-254 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
PIKHPIBO_00282 5.3e-264 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
PIKHPIBO_00283 1.3e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
PIKHPIBO_00284 6.7e-188 S response regulator aspartate phosphatase
PIKHPIBO_00285 5.2e-139 IQ Enoyl-(Acyl carrier protein) reductase
PIKHPIBO_00286 1e-35 EGP Major facilitator Superfamily
PIKHPIBO_00287 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
PIKHPIBO_00288 1e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
PIKHPIBO_00289 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PIKHPIBO_00290 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PIKHPIBO_00291 1.4e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIKHPIBO_00292 2.8e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
PIKHPIBO_00293 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
PIKHPIBO_00294 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
PIKHPIBO_00295 9.7e-138 terC P Protein of unknown function (DUF475)
PIKHPIBO_00296 0.0 yceG S Putative component of 'biosynthetic module'
PIKHPIBO_00297 2.3e-193 yceH P Belongs to the TelA family
PIKHPIBO_00298 1.4e-215 naiP P Uncharacterised MFS-type transporter YbfB
PIKHPIBO_00299 3.9e-229 proV 3.6.3.32 E glycine betaine
PIKHPIBO_00300 1.6e-138 opuAB P glycine betaine
PIKHPIBO_00301 3.1e-164 opuAC E glycine betaine
PIKHPIBO_00302 6.6e-212 amhX S amidohydrolase
PIKHPIBO_00303 1.1e-230 ycgA S Membrane
PIKHPIBO_00304 4.1e-81 ycgB
PIKHPIBO_00305 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
PIKHPIBO_00306 3.7e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PIKHPIBO_00307 1.1e-260 mdr EGP Major facilitator Superfamily
PIKHPIBO_00308 1.8e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
PIKHPIBO_00309 4.7e-114 ycgF E Lysine exporter protein LysE YggA
PIKHPIBO_00310 2.9e-150 yqcI S YqcI/YcgG family
PIKHPIBO_00311 2.2e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
PIKHPIBO_00312 1.3e-113 ycgI S Domain of unknown function (DUF1989)
PIKHPIBO_00313 1.8e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PIKHPIBO_00315 6.2e-108 tmrB S AAA domain
PIKHPIBO_00316 1.1e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
PIKHPIBO_00317 1.8e-221 G COG0477 Permeases of the major facilitator superfamily
PIKHPIBO_00318 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PIKHPIBO_00319 1.3e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
PIKHPIBO_00320 1.1e-147 ycgL S Predicted nucleotidyltransferase
PIKHPIBO_00321 2.3e-170 ycgM E Proline dehydrogenase
PIKHPIBO_00322 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
PIKHPIBO_00323 1.7e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PIKHPIBO_00324 6.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
PIKHPIBO_00325 4.6e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PIKHPIBO_00326 3.6e-279 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
PIKHPIBO_00327 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
PIKHPIBO_00328 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PIKHPIBO_00329 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PIKHPIBO_00330 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
PIKHPIBO_00331 3.4e-222 nasA P COG2223 Nitrate nitrite transporter
PIKHPIBO_00332 3.2e-228 yciC S GTPases (G3E family)
PIKHPIBO_00333 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PIKHPIBO_00334 1.4e-72 yckC S membrane
PIKHPIBO_00335 2.2e-51 S Protein of unknown function (DUF2680)
PIKHPIBO_00336 9.5e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PIKHPIBO_00337 2.9e-69 nin S Competence protein J (ComJ)
PIKHPIBO_00338 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
PIKHPIBO_00339 6.2e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
PIKHPIBO_00340 2.8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
PIKHPIBO_00341 6.3e-63 hxlR K transcriptional
PIKHPIBO_00342 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_00343 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_00344 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
PIKHPIBO_00345 1.7e-139 srfAD Q thioesterase
PIKHPIBO_00346 2.7e-249 bamJ E Aminotransferase class I and II
PIKHPIBO_00347 1.5e-129 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
PIKHPIBO_00348 4.5e-109 yczE S membrane
PIKHPIBO_00349 3.4e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PIKHPIBO_00350 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
PIKHPIBO_00351 6.1e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PIKHPIBO_00352 3.9e-159 bsdA K LysR substrate binding domain
PIKHPIBO_00353 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PIKHPIBO_00354 3.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
PIKHPIBO_00355 5.8e-38 bsdD 4.1.1.61 S response to toxic substance
PIKHPIBO_00356 1.7e-76 yclD
PIKHPIBO_00357 3.2e-270 dtpT E amino acid peptide transporter
PIKHPIBO_00358 2.3e-280 yclG M Pectate lyase superfamily protein
PIKHPIBO_00360 1e-293 gerKA EG Spore germination protein
PIKHPIBO_00361 1.6e-235 gerKC S spore germination
PIKHPIBO_00362 5.1e-196 gerKB F Spore germination protein
PIKHPIBO_00363 8.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIKHPIBO_00364 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIKHPIBO_00365 7.9e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
PIKHPIBO_00366 7.7e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
PIKHPIBO_00367 2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
PIKHPIBO_00368 4.1e-217 yxeP 3.5.1.47 E hydrolase activity
PIKHPIBO_00369 1.6e-252 yxeQ S MmgE/PrpD family
PIKHPIBO_00370 1.7e-122 yclH P ABC transporter
PIKHPIBO_00371 2e-229 yclI V ABC transporter (permease) YclI
PIKHPIBO_00372 5.2e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_00373 1.2e-258 T PhoQ Sensor
PIKHPIBO_00374 1.6e-80 S aspartate phosphatase
PIKHPIBO_00376 6.1e-252 lysC 2.7.2.4 E Belongs to the aspartokinase family
PIKHPIBO_00377 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIKHPIBO_00378 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIKHPIBO_00379 8.1e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
PIKHPIBO_00380 1.9e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
PIKHPIBO_00381 2.5e-248 ycnB EGP Major facilitator Superfamily
PIKHPIBO_00382 2.7e-152 ycnC K Transcriptional regulator
PIKHPIBO_00383 5.2e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
PIKHPIBO_00384 2.3e-44 ycnE S Monooxygenase
PIKHPIBO_00385 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
PIKHPIBO_00386 2.6e-266 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIKHPIBO_00387 3.8e-219 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PIKHPIBO_00388 4.6e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PIKHPIBO_00389 3.6e-149 glcU U Glucose uptake
PIKHPIBO_00390 1.9e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIKHPIBO_00391 7.8e-98 ycnI S protein conserved in bacteria
PIKHPIBO_00392 2.3e-298 ycnJ P protein, homolog of Cu resistance protein CopC
PIKHPIBO_00393 2.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
PIKHPIBO_00394 1.6e-55
PIKHPIBO_00395 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
PIKHPIBO_00396 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
PIKHPIBO_00397 2.2e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
PIKHPIBO_00398 6.6e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
PIKHPIBO_00400 2.3e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PIKHPIBO_00401 7.9e-140 ycsF S Belongs to the UPF0271 (lamB) family
PIKHPIBO_00402 1e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
PIKHPIBO_00403 1.6e-148 ycsI S Belongs to the D-glutamate cyclase family
PIKHPIBO_00404 5.1e-136 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
PIKHPIBO_00405 1.4e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
PIKHPIBO_00406 1.5e-130 kipR K Transcriptional regulator
PIKHPIBO_00407 6e-117 ycsK E anatomical structure formation involved in morphogenesis
PIKHPIBO_00409 2.5e-55 yczJ S biosynthesis
PIKHPIBO_00410 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
PIKHPIBO_00411 3.4e-174 ydhF S Oxidoreductase
PIKHPIBO_00412 0.0 mtlR K transcriptional regulator, MtlR
PIKHPIBO_00413 7.2e-286 ydaB IQ acyl-CoA ligase
PIKHPIBO_00414 9.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIKHPIBO_00415 1.3e-93 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
PIKHPIBO_00416 2.3e-113 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PIKHPIBO_00417 1.4e-77 ydaG 1.4.3.5 S general stress protein
PIKHPIBO_00418 4.6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PIKHPIBO_00419 2.7e-48 ydzA EGP Major facilitator Superfamily
PIKHPIBO_00420 4.3e-74 lrpC K Transcriptional regulator
PIKHPIBO_00421 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PIKHPIBO_00422 1.2e-197 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
PIKHPIBO_00423 1.1e-147 ydaK T Diguanylate cyclase, GGDEF domain
PIKHPIBO_00424 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
PIKHPIBO_00425 2.5e-231 ydaM M Glycosyl transferase family group 2
PIKHPIBO_00426 0.0 ydaN S Bacterial cellulose synthase subunit
PIKHPIBO_00427 0.0 ydaO E amino acid
PIKHPIBO_00428 6.3e-73 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PIKHPIBO_00429 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PIKHPIBO_00430 5.6e-50 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PIKHPIBO_00431 1.5e-50 V HNH endonuclease
PIKHPIBO_00432 6e-89 yokH G SMI1 / KNR4 family
PIKHPIBO_00433 3.1e-25
PIKHPIBO_00434 2e-208 S Histidine kinase
PIKHPIBO_00436 9.4e-12
PIKHPIBO_00438 9e-77
PIKHPIBO_00439 8.4e-100
PIKHPIBO_00440 2.1e-39
PIKHPIBO_00441 2e-225 mntH P H( )-stimulated, divalent metal cation uptake system
PIKHPIBO_00443 6.5e-34 ydaT
PIKHPIBO_00444 6e-70 yvaD S Family of unknown function (DUF5360)
PIKHPIBO_00445 7e-54 yvaE P Small Multidrug Resistance protein
PIKHPIBO_00446 4e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
PIKHPIBO_00448 9.8e-58 ydbB G Cupin domain
PIKHPIBO_00449 1.7e-60 ydbC S Domain of unknown function (DUF4937
PIKHPIBO_00450 4.2e-155 ydbD P Catalase
PIKHPIBO_00451 3.2e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PIKHPIBO_00452 5.5e-300 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PIKHPIBO_00453 6.7e-119 dctR T COG4565 Response regulator of citrate malate metabolism
PIKHPIBO_00454 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIKHPIBO_00455 5.7e-157 ydbI S AI-2E family transporter
PIKHPIBO_00456 5e-173 ydbJ V ABC transporter, ATP-binding protein
PIKHPIBO_00457 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PIKHPIBO_00458 2.1e-52 ydbL
PIKHPIBO_00459 1.8e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
PIKHPIBO_00460 3.3e-10 S Fur-regulated basic protein B
PIKHPIBO_00461 5.8e-09 S Fur-regulated basic protein A
PIKHPIBO_00462 8.1e-120 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PIKHPIBO_00463 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PIKHPIBO_00464 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PIKHPIBO_00465 6.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PIKHPIBO_00466 2.9e-247 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PIKHPIBO_00467 1.3e-60 ydbS S Bacterial PH domain
PIKHPIBO_00468 2e-261 ydbT S Membrane
PIKHPIBO_00469 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
PIKHPIBO_00470 2e-56 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PIKHPIBO_00471 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
PIKHPIBO_00472 6.9e-220 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PIKHPIBO_00473 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PIKHPIBO_00474 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
PIKHPIBO_00475 6.1e-146 rsbR T Positive regulator of sigma-B
PIKHPIBO_00476 6.8e-57 rsbS T antagonist
PIKHPIBO_00477 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PIKHPIBO_00478 1.7e-187 rsbU 3.1.3.3 KT phosphatase
PIKHPIBO_00479 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
PIKHPIBO_00480 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PIKHPIBO_00481 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIKHPIBO_00482 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
PIKHPIBO_00483 0.0 yhgF K COG2183 Transcriptional accessory protein
PIKHPIBO_00484 1.7e-14
PIKHPIBO_00485 5.6e-58 ydcK S Belongs to the SprT family
PIKHPIBO_00493 4.1e-95 ywrO S Flavodoxin-like fold
PIKHPIBO_00494 1.1e-227 proP EGP Transporter
PIKHPIBO_00495 7.1e-47 ohrR K Transcriptional regulator
PIKHPIBO_00496 4.2e-31 S Domain of unknown function with cystatin-like fold (DUF4467)
PIKHPIBO_00497 1.5e-29 S Domain of unknown function with cystatin-like fold (DUF4467)
PIKHPIBO_00498 1.2e-73 maoC I N-terminal half of MaoC dehydratase
PIKHPIBO_00499 1.4e-64 yyaQ S YjbR
PIKHPIBO_00500 2.3e-66 ywnA K Transcriptional regulator
PIKHPIBO_00501 3.8e-111 ywnB S NAD(P)H-binding
PIKHPIBO_00502 4.2e-132 EGP Major Facilitator Superfamily
PIKHPIBO_00503 1.1e-56 K Transcriptional regulator
PIKHPIBO_00504 1.8e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
PIKHPIBO_00505 1.4e-30 cspL K Cold shock
PIKHPIBO_00506 5.2e-78 carD K Transcription factor
PIKHPIBO_00507 5e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PIKHPIBO_00508 2e-100 S Protein of unknown function (DUF2812)
PIKHPIBO_00509 1.3e-51 K Transcriptional regulator PadR-like family
PIKHPIBO_00510 3.5e-171 ybfA 3.4.15.5 K FR47-like protein
PIKHPIBO_00511 5.2e-232 ybfB G COG0477 Permeases of the major facilitator superfamily
PIKHPIBO_00512 7.3e-183 S Patatin-like phospholipase
PIKHPIBO_00513 1.4e-78 S DinB superfamily
PIKHPIBO_00514 5e-117 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
PIKHPIBO_00515 7.8e-67 K COG1802 Transcriptional regulators
PIKHPIBO_00516 1.1e-38 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
PIKHPIBO_00517 1.4e-141 sdaC E Serine transporter
PIKHPIBO_00518 1.2e-163 E Peptidase dimerisation domain
PIKHPIBO_00519 1.7e-125 rhaS5 K helix_turn_helix, arabinose operon control protein
PIKHPIBO_00520 2.9e-176 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PIKHPIBO_00521 2.9e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIKHPIBO_00522 6.1e-193 ydeG EGP Major facilitator superfamily
PIKHPIBO_00523 2e-52 3.6.1.55 F Belongs to the Nudix hydrolase family
PIKHPIBO_00526 1.3e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
PIKHPIBO_00527 6.5e-168 czcD P COG1230 Co Zn Cd efflux system component
PIKHPIBO_00528 7e-200 trkA P Oxidoreductase
PIKHPIBO_00531 5e-85 ykkA S Protein of unknown function (DUF664)
PIKHPIBO_00532 3.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
PIKHPIBO_00533 9e-195 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
PIKHPIBO_00534 3.1e-52 ydeH
PIKHPIBO_00535 6.8e-165 S Sodium Bile acid symporter family
PIKHPIBO_00536 5.8e-202 adhA 1.1.1.1 C alcohol dehydrogenase
PIKHPIBO_00537 1.4e-66 yraB K helix_turn_helix, mercury resistance
PIKHPIBO_00538 4.8e-214 mleN_2 C antiporter
PIKHPIBO_00539 2.3e-262 K helix_turn_helix gluconate operon transcriptional repressor
PIKHPIBO_00540 1.6e-114 paiB K Transcriptional regulator
PIKHPIBO_00542 7.6e-182 ydeR EGP Major facilitator Superfamily
PIKHPIBO_00543 1.3e-102 ydeS K Transcriptional regulator
PIKHPIBO_00544 6.3e-157 ydeK EG -transporter
PIKHPIBO_00545 4.4e-266 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIKHPIBO_00546 9.5e-49 yraD M Spore coat protein
PIKHPIBO_00547 5.1e-25 yraE
PIKHPIBO_00548 6.1e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PIKHPIBO_00549 8.4e-63 yraF M Spore coat protein
PIKHPIBO_00550 1.2e-36 yraG
PIKHPIBO_00551 4.3e-215 ydfH 2.7.13.3 T Histidine kinase
PIKHPIBO_00552 3.2e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIKHPIBO_00553 0.0 ydfJ S drug exporters of the RND superfamily
PIKHPIBO_00554 1e-133 puuD S Peptidase C26
PIKHPIBO_00555 1e-301 expZ S ABC transporter
PIKHPIBO_00556 1.2e-99 ynaD J Acetyltransferase (GNAT) domain
PIKHPIBO_00557 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
PIKHPIBO_00558 3.9e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
PIKHPIBO_00559 5.1e-210 tcaB EGP Major facilitator Superfamily
PIKHPIBO_00560 6.8e-226 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PIKHPIBO_00561 5.6e-155 K Helix-turn-helix XRE-family like proteins
PIKHPIBO_00562 6.5e-123 ydhB S membrane transporter protein
PIKHPIBO_00563 2.9e-81 bltD 2.3.1.57 K FR47-like protein
PIKHPIBO_00564 4.1e-150 bltR K helix_turn_helix, mercury resistance
PIKHPIBO_00565 1.1e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PIKHPIBO_00566 1.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
PIKHPIBO_00567 1.2e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
PIKHPIBO_00568 1.4e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
PIKHPIBO_00569 2e-118 ydhC K FCD
PIKHPIBO_00570 9.2e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PIKHPIBO_00573 3.8e-262 pbpE V Beta-lactamase
PIKHPIBO_00575 1.2e-97 ydhK M Protein of unknown function (DUF1541)
PIKHPIBO_00576 1.2e-195 pbuE EGP Major facilitator Superfamily
PIKHPIBO_00577 1.3e-133 ydhQ K UTRA
PIKHPIBO_00578 4.9e-117 K FCD
PIKHPIBO_00579 7.4e-217 yeaN P COG2807 Cyanate permease
PIKHPIBO_00580 2.6e-49 sugE P Small Multidrug Resistance protein
PIKHPIBO_00581 2.3e-51 ykkC P Small Multidrug Resistance protein
PIKHPIBO_00582 5.3e-104 yvdT K Transcriptional regulator
PIKHPIBO_00583 1.2e-296 yveA E amino acid
PIKHPIBO_00584 5.1e-164 ydhU P Catalase
PIKHPIBO_00585 3.5e-82 yndB S Activator of Hsp90 ATPase homolog 1-like protein
PIKHPIBO_00586 1.8e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
PIKHPIBO_00587 1.5e-248 iolT EGP Major facilitator Superfamily
PIKHPIBO_00590 1.2e-39 S COG NOG14552 non supervised orthologous group
PIKHPIBO_00591 7.8e-08
PIKHPIBO_00593 1.3e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PIKHPIBO_00594 2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
PIKHPIBO_00595 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
PIKHPIBO_00596 5.8e-82 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PIKHPIBO_00597 5.1e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PIKHPIBO_00598 0.0 ydiF S ABC transporter
PIKHPIBO_00599 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PIKHPIBO_00600 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PIKHPIBO_00601 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PIKHPIBO_00602 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PIKHPIBO_00603 1.7e-27 ydiK S Domain of unknown function (DUF4305)
PIKHPIBO_00604 2.1e-126 ydiL S CAAX protease self-immunity
PIKHPIBO_00605 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PIKHPIBO_00606 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PIKHPIBO_00607 1.5e-24 S Protein of unknown function (DUF4064)
PIKHPIBO_00609 0.0 K NB-ARC domain
PIKHPIBO_00610 2.5e-200 gutB 1.1.1.14 E Dehydrogenase
PIKHPIBO_00611 4.4e-250 gutA G MFS/sugar transport protein
PIKHPIBO_00612 1.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
PIKHPIBO_00613 7.3e-31 yjdJ S Domain of unknown function (DUF4306)
PIKHPIBO_00614 6.7e-114 pspA KT Phage shock protein A
PIKHPIBO_00615 6.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PIKHPIBO_00616 3.1e-120 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
PIKHPIBO_00617 4.5e-151 ydjI S virion core protein (lumpy skin disease virus)
PIKHPIBO_00618 0.0 yrhL I Acyltransferase family
PIKHPIBO_00619 1.2e-147 rsiV S Protein of unknown function (DUF3298)
PIKHPIBO_00620 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
PIKHPIBO_00621 4.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
PIKHPIBO_00622 7.1e-62 ydjM M Lytic transglycolase
PIKHPIBO_00623 4.7e-135 ydjN U Involved in the tonB-independent uptake of proteins
PIKHPIBO_00625 7.2e-35 ydjO S Cold-inducible protein YdjO
PIKHPIBO_00626 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
PIKHPIBO_00627 7.3e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
PIKHPIBO_00628 2.2e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PIKHPIBO_00629 3.5e-177 yeaC S COG0714 MoxR-like ATPases
PIKHPIBO_00630 5.4e-212 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PIKHPIBO_00631 0.0 yebA E COG1305 Transglutaminase-like enzymes
PIKHPIBO_00632 9.6e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PIKHPIBO_00633 1e-139 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
PIKHPIBO_00634 8.7e-117 F ATP-grasp domain
PIKHPIBO_00635 3.9e-106 pphA 5.4.2.9 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PIKHPIBO_00636 4.1e-135 aspC 2.6.1.1 E DegT/DnrJ/EryC1/StrS aminotransferase family
PIKHPIBO_00637 3.9e-149 yqjV G Major Facilitator Superfamily
PIKHPIBO_00638 1.3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
PIKHPIBO_00639 2.1e-247 S Domain of unknown function (DUF4179)
PIKHPIBO_00640 6.2e-209 pbuG S permease
PIKHPIBO_00641 7.3e-125 yebC M Membrane
PIKHPIBO_00643 2e-92 yebE S UPF0316 protein
PIKHPIBO_00644 6.1e-28 yebG S NETI protein
PIKHPIBO_00645 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PIKHPIBO_00646 4e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PIKHPIBO_00647 3.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PIKHPIBO_00648 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PIKHPIBO_00649 6.4e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIKHPIBO_00650 1.9e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIKHPIBO_00651 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIKHPIBO_00652 1.1e-270 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PIKHPIBO_00653 1e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PIKHPIBO_00654 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PIKHPIBO_00655 2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PIKHPIBO_00656 2.4e-234 purD 6.3.4.13 F Belongs to the GARS family
PIKHPIBO_00657 1.2e-25 S Protein of unknown function (DUF2892)
PIKHPIBO_00658 0.0 yerA 3.5.4.2 F adenine deaminase
PIKHPIBO_00659 4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
PIKHPIBO_00660 2.4e-50 yerC S protein conserved in bacteria
PIKHPIBO_00661 7.9e-304 yerD 1.4.7.1 E Belongs to the glutamate synthase family
PIKHPIBO_00662 4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PIKHPIBO_00663 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PIKHPIBO_00664 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PIKHPIBO_00665 1.4e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
PIKHPIBO_00666 5e-195 yerI S homoserine kinase type II (protein kinase fold)
PIKHPIBO_00667 1.3e-120 sapB S MgtC SapB transporter
PIKHPIBO_00668 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PIKHPIBO_00669 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIKHPIBO_00670 4.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PIKHPIBO_00671 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIKHPIBO_00672 1.5e-152 yerO K Transcriptional regulator
PIKHPIBO_00673 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PIKHPIBO_00674 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PIKHPIBO_00675 1.3e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIKHPIBO_00676 1.8e-91 V ABC transporter, ATP-binding protein
PIKHPIBO_00677 1.1e-158 V FtsX-like permease family
PIKHPIBO_00678 1.7e-160 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
PIKHPIBO_00679 3.8e-138 cylB V ABC-2 type transporter
PIKHPIBO_00680 1.9e-12 S Protein of unknown function, DUF600
PIKHPIBO_00681 3.3e-80 S Protein of unknown function, DUF600
PIKHPIBO_00682 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
PIKHPIBO_00683 8.4e-21
PIKHPIBO_00684 8.7e-257 yobL S Bacterial EndoU nuclease
PIKHPIBO_00685 9.4e-127 yeeN K transcriptional regulatory protein
PIKHPIBO_00688 2.4e-108 aadK G Streptomycin adenylyltransferase
PIKHPIBO_00689 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
PIKHPIBO_00690 3.3e-45 cotJB S CotJB protein
PIKHPIBO_00691 8.9e-104 cotJC P Spore Coat
PIKHPIBO_00692 2.1e-91 yesJ K Acetyltransferase (GNAT) family
PIKHPIBO_00694 4.1e-119 yetF S membrane
PIKHPIBO_00695 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
PIKHPIBO_00696 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIKHPIBO_00697 4.1e-153 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PIKHPIBO_00698 2.9e-137 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
PIKHPIBO_00699 7.6e-112 cysT O COG0555 ABC-type sulfate transport system, permease component
PIKHPIBO_00700 3.5e-104 cysW P COG4208 ABC-type sulfate transport system, permease component
PIKHPIBO_00701 5.9e-133 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PIKHPIBO_00702 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
PIKHPIBO_00703 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
PIKHPIBO_00704 8.2e-106 yetJ S Belongs to the BI1 family
PIKHPIBO_00705 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
PIKHPIBO_00706 2.4e-206 yetM CH FAD binding domain
PIKHPIBO_00707 7.5e-197 yetN S Protein of unknown function (DUF3900)
PIKHPIBO_00708 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
PIKHPIBO_00710 6.9e-50 MA20_23570 K Winged helix DNA-binding domain
PIKHPIBO_00711 1.6e-163 V ATPases associated with a variety of cellular activities
PIKHPIBO_00712 3.7e-126 V ABC-2 type transporter
PIKHPIBO_00714 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PIKHPIBO_00715 7.9e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
PIKHPIBO_00716 2.4e-172 yfnG 4.2.1.45 M dehydratase
PIKHPIBO_00717 1.8e-178 yfnF M Nucleotide-diphospho-sugar transferase
PIKHPIBO_00718 1.9e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
PIKHPIBO_00719 2.4e-186 yfnD M Nucleotide-diphospho-sugar transferase
PIKHPIBO_00720 2.3e-218 fsr P COG0477 Permeases of the major facilitator superfamily
PIKHPIBO_00721 5.6e-245 yfnA E amino acid
PIKHPIBO_00722 2e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PIKHPIBO_00723 6e-104 yfmS NT chemotaxis protein
PIKHPIBO_00724 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
PIKHPIBO_00725 5.5e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PIKHPIBO_00726 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PIKHPIBO_00727 1.8e-69 yfmP K transcriptional
PIKHPIBO_00728 2.1e-208 yfmO EGP Major facilitator Superfamily
PIKHPIBO_00729 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PIKHPIBO_00730 2.1e-205 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
PIKHPIBO_00731 1e-41 yfmK 2.3.1.128 K acetyltransferase
PIKHPIBO_00732 2.1e-188 yfmJ S N-terminal domain of oxidoreductase
PIKHPIBO_00733 1.2e-24 S Protein of unknown function (DUF3212)
PIKHPIBO_00734 1.3e-57 yflT S Heat induced stress protein YflT
PIKHPIBO_00735 6.5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
PIKHPIBO_00736 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
PIKHPIBO_00737 1e-27 Q PFAM Collagen triple helix
PIKHPIBO_00740 9.2e-15 Q calcium- and calmodulin-responsive adenylate cyclase activity
PIKHPIBO_00741 7.3e-78 M1-820 Q Collagen triple helix repeat (20 copies)
PIKHPIBO_00742 0.0 ywpD T PhoQ Sensor
PIKHPIBO_00743 2.2e-151 M1-574 T Transcriptional regulatory protein, C terminal
PIKHPIBO_00744 0.0 M1-568 M cell wall anchor domain
PIKHPIBO_00745 4.6e-80 srtA 3.4.22.70 M Sortase family
PIKHPIBO_00746 3.8e-269 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PIKHPIBO_00747 1.8e-119 citT T response regulator
PIKHPIBO_00748 1.2e-177 yflP S Tripartite tricarboxylate transporter family receptor
PIKHPIBO_00749 1.4e-226 citM C Citrate transporter
PIKHPIBO_00750 3.3e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
PIKHPIBO_00751 7.9e-218 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PIKHPIBO_00752 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PIKHPIBO_00753 1.1e-121 yflK S protein conserved in bacteria
PIKHPIBO_00754 1.5e-14 yflJ S Protein of unknown function (DUF2639)
PIKHPIBO_00755 7e-19 yflI
PIKHPIBO_00756 3.1e-50 yflH S Protein of unknown function (DUF3243)
PIKHPIBO_00757 2.3e-136 map 3.4.11.18 E Methionine aminopeptidase
PIKHPIBO_00758 3.3e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
PIKHPIBO_00759 3.7e-73 yfmQ S Uncharacterised protein from bacillus cereus group
PIKHPIBO_00760 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PIKHPIBO_00761 7.8e-64 yhdN S Domain of unknown function (DUF1992)
PIKHPIBO_00762 9.8e-79 cotP O Belongs to the small heat shock protein (HSP20) family
PIKHPIBO_00763 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
PIKHPIBO_00764 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
PIKHPIBO_00765 1.5e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PIKHPIBO_00766 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PIKHPIBO_00767 1.1e-127 treR K transcriptional
PIKHPIBO_00768 1.2e-123 yfkO C nitroreductase
PIKHPIBO_00769 4.2e-125 yibF S YibE/F-like protein
PIKHPIBO_00770 1.5e-198 yibE S YibE/F-like protein
PIKHPIBO_00771 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
PIKHPIBO_00772 7.8e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
PIKHPIBO_00773 9.8e-186 K helix_turn _helix lactose operon repressor
PIKHPIBO_00774 5.3e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PIKHPIBO_00775 3.4e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PIKHPIBO_00776 5.3e-191 ydiM EGP Major facilitator Superfamily
PIKHPIBO_00777 2.7e-29 yfkK S Belongs to the UPF0435 family
PIKHPIBO_00778 3.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIKHPIBO_00779 2e-52 yfkI S gas vesicle protein
PIKHPIBO_00780 6.8e-145 yihY S Belongs to the UPF0761 family
PIKHPIBO_00781 2.5e-07
PIKHPIBO_00782 6.5e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
PIKHPIBO_00783 1.7e-185 cax P COG0387 Ca2 H antiporter
PIKHPIBO_00784 1.6e-143 yfkD S YfkD-like protein
PIKHPIBO_00785 5.7e-144 yfkC M Mechanosensitive ion channel
PIKHPIBO_00786 1.9e-219 yfkA S YfkB-like domain
PIKHPIBO_00787 4.9e-27 yfjT
PIKHPIBO_00788 9.9e-154 pdaA G deacetylase
PIKHPIBO_00789 1.8e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PIKHPIBO_00790 8.5e-184 corA P Mediates influx of magnesium ions
PIKHPIBO_00791 6.3e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PIKHPIBO_00792 1.3e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIKHPIBO_00794 1e-44 S YfzA-like protein
PIKHPIBO_00795 1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PIKHPIBO_00796 1.2e-88 yfjM S Psort location Cytoplasmic, score
PIKHPIBO_00797 6.4e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PIKHPIBO_00798 4.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PIKHPIBO_00799 3.5e-211 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PIKHPIBO_00800 1.5e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PIKHPIBO_00801 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
PIKHPIBO_00802 4.2e-15 sspH S Belongs to the SspH family
PIKHPIBO_00803 5.5e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PIKHPIBO_00804 1.5e-138 glvR F Helix-turn-helix domain, rpiR family
PIKHPIBO_00805 5.4e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PIKHPIBO_00806 0.0 yfiB3 V ABC transporter
PIKHPIBO_00807 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
PIKHPIBO_00808 2.4e-63 mhqP S DoxX
PIKHPIBO_00809 3.5e-160 yfiE 1.13.11.2 S glyoxalase
PIKHPIBO_00810 1.4e-167 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PIKHPIBO_00811 1.7e-96 padR K transcriptional
PIKHPIBO_00812 4.2e-112 1.6.5.2 S NADPH-dependent FMN reductase
PIKHPIBO_00813 2.9e-180 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PIKHPIBO_00814 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
PIKHPIBO_00815 9.9e-45 yrdF K ribonuclease inhibitor
PIKHPIBO_00816 2.2e-96 yfiT S Belongs to the metal hydrolase YfiT family
PIKHPIBO_00817 3.6e-288 yfiU EGP Major facilitator Superfamily
PIKHPIBO_00818 9.5e-83 yfiV K transcriptional
PIKHPIBO_00819 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PIKHPIBO_00820 2.6e-163 yfhB 5.3.3.17 S PhzF family
PIKHPIBO_00821 3.3e-106 yfhC C nitroreductase
PIKHPIBO_00822 2.1e-25 yfhD S YfhD-like protein
PIKHPIBO_00824 2.6e-166 yfhF S nucleoside-diphosphate sugar epimerase
PIKHPIBO_00825 3.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
PIKHPIBO_00826 8.8e-53 yfhH S Protein of unknown function (DUF1811)
PIKHPIBO_00827 4.5e-206 yfhI EGP Major facilitator Superfamily
PIKHPIBO_00829 1.4e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
PIKHPIBO_00830 2.2e-44 yfhJ S WVELL protein
PIKHPIBO_00831 1e-93 batE T Bacterial SH3 domain homologues
PIKHPIBO_00832 5.7e-34 yfhL S SdpI/YhfL protein family
PIKHPIBO_00833 7e-169 yfhM S Alpha/beta hydrolase family
PIKHPIBO_00834 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PIKHPIBO_00835 0.0 yfhO S Bacterial membrane protein YfhO
PIKHPIBO_00836 1e-184 yfhP S membrane-bound metal-dependent
PIKHPIBO_00837 4.7e-210 mutY L A G-specific
PIKHPIBO_00838 8.2e-37 yfhS
PIKHPIBO_00839 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIKHPIBO_00841 1.5e-37 ygaB S YgaB-like protein
PIKHPIBO_00842 2.2e-104 ygaC J Belongs to the UPF0374 family
PIKHPIBO_00843 4.2e-306 ygaD V ABC transporter
PIKHPIBO_00844 3.2e-179 ygaE S Membrane
PIKHPIBO_00845 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
PIKHPIBO_00846 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
PIKHPIBO_00847 1.8e-80 perR P Belongs to the Fur family
PIKHPIBO_00848 1.5e-56 ygzB S UPF0295 protein
PIKHPIBO_00849 8.2e-165 ygxA S Nucleotidyltransferase-like
PIKHPIBO_00850 3.4e-39 S COG NOG14552 non supervised orthologous group
PIKHPIBO_00855 7.8e-08
PIKHPIBO_00863 1.6e-08
PIKHPIBO_00867 5.3e-284 C Na+/H+ antiporter family
PIKHPIBO_00868 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
PIKHPIBO_00869 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PIKHPIBO_00870 1.2e-263 ygaK C Berberine and berberine like
PIKHPIBO_00872 4.4e-231 oppA5 E PFAM extracellular solute-binding protein family 5
PIKHPIBO_00873 9.2e-138 appB P Binding-protein-dependent transport system inner membrane component
PIKHPIBO_00874 3.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIKHPIBO_00875 5.8e-135 oppD3 P Belongs to the ABC transporter superfamily
PIKHPIBO_00876 7.4e-135 oppF3 E Belongs to the ABC transporter superfamily
PIKHPIBO_00877 1.7e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PIKHPIBO_00878 2.4e-183 S Amidohydrolase
PIKHPIBO_00879 4.2e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PIKHPIBO_00880 7.7e-180 ssuA M Sulfonate ABC transporter
PIKHPIBO_00881 2.6e-144 ssuC P ABC transporter (permease)
PIKHPIBO_00882 5.5e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
PIKHPIBO_00883 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIKHPIBO_00884 3.3e-80 ygaO
PIKHPIBO_00886 1.1e-112 yhzB S B3/4 domain
PIKHPIBO_00887 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PIKHPIBO_00888 5.3e-175 yhbB S Putative amidase domain
PIKHPIBO_00889 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PIKHPIBO_00890 7.8e-109 yhbD K Protein of unknown function (DUF4004)
PIKHPIBO_00891 2.3e-29 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
PIKHPIBO_00892 3.3e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
PIKHPIBO_00894 0.0 prkA T Ser protein kinase
PIKHPIBO_00895 2.7e-216 yhbH S Belongs to the UPF0229 family
PIKHPIBO_00896 4.6e-74 yhbI K DNA-binding transcription factor activity
PIKHPIBO_00897 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
PIKHPIBO_00898 8.4e-285 yhcA EGP Major facilitator Superfamily
PIKHPIBO_00899 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
PIKHPIBO_00900 3.8e-55 yhcC
PIKHPIBO_00901 1.3e-52
PIKHPIBO_00902 1.6e-61 yhcF K Transcriptional regulator
PIKHPIBO_00903 3.6e-126 yhcG V ABC transporter, ATP-binding protein
PIKHPIBO_00904 4.1e-167 yhcH V ABC transporter, ATP-binding protein
PIKHPIBO_00905 3.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PIKHPIBO_00906 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
PIKHPIBO_00907 4.2e-147 metQ M Belongs to the nlpA lipoprotein family
PIKHPIBO_00908 6e-186 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
PIKHPIBO_00909 9.2e-221 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIKHPIBO_00910 1e-54 yhcM
PIKHPIBO_00911 9.6e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PIKHPIBO_00912 7.3e-161 yhcP
PIKHPIBO_00913 5.8e-115 yhcQ M Spore coat protein
PIKHPIBO_00914 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
PIKHPIBO_00915 3.4e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
PIKHPIBO_00916 1.1e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PIKHPIBO_00917 1.3e-69 yhcU S Family of unknown function (DUF5365)
PIKHPIBO_00918 2.6e-68 yhcV S COG0517 FOG CBS domain
PIKHPIBO_00919 5.5e-124 yhcW 5.4.2.6 S hydrolase
PIKHPIBO_00920 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PIKHPIBO_00921 3.2e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PIKHPIBO_00922 1.5e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PIKHPIBO_00923 4.5e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
PIKHPIBO_00924 6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PIKHPIBO_00925 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PIKHPIBO_00926 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PIKHPIBO_00927 3.6e-205 yhcY 2.7.13.3 T Histidine kinase
PIKHPIBO_00928 1e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIKHPIBO_00929 4.3e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
PIKHPIBO_00930 7.3e-39 yhdB S YhdB-like protein
PIKHPIBO_00931 1.5e-52 yhdC S Protein of unknown function (DUF3889)
PIKHPIBO_00932 5.4e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PIKHPIBO_00933 5.6e-74 nsrR K Transcriptional regulator
PIKHPIBO_00934 4.5e-256 ygxB M Conserved TM helix
PIKHPIBO_00935 1.2e-271 ycgB S Stage V sporulation protein R
PIKHPIBO_00936 8.9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
PIKHPIBO_00937 1.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PIKHPIBO_00938 9e-164 citR K Transcriptional regulator
PIKHPIBO_00939 4.9e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
PIKHPIBO_00940 1.6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIKHPIBO_00941 9.1e-251 yhdG E amino acid
PIKHPIBO_00942 2.6e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PIKHPIBO_00943 8.1e-45 yhdK S Sigma-M inhibitor protein
PIKHPIBO_00944 6.6e-201 yhdL S Sigma factor regulator N-terminal
PIKHPIBO_00945 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
PIKHPIBO_00946 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PIKHPIBO_00947 1.6e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PIKHPIBO_00948 4.3e-71 cueR K transcriptional
PIKHPIBO_00949 7.2e-225 yhdR 2.6.1.1 E Aminotransferase
PIKHPIBO_00950 4.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PIKHPIBO_00951 2.9e-257 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
PIKHPIBO_00952 6.1e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIKHPIBO_00953 4.9e-61 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIKHPIBO_00954 6.5e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PIKHPIBO_00956 4.6e-205 yhdY M Mechanosensitive ion channel
PIKHPIBO_00957 4.5e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PIKHPIBO_00958 3e-156 yheN G deacetylase
PIKHPIBO_00959 6.9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PIKHPIBO_00960 5.1e-87 pksA K Transcriptional regulator
PIKHPIBO_00961 1.8e-93 ymcC S Membrane
PIKHPIBO_00962 3.6e-85 T universal stress protein
PIKHPIBO_00964 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
PIKHPIBO_00965 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
PIKHPIBO_00966 6.2e-111 yheG GM NAD(P)H-binding
PIKHPIBO_00968 5.8e-29 sspB S spore protein
PIKHPIBO_00969 1.7e-36 yheE S Family of unknown function (DUF5342)
PIKHPIBO_00970 5.1e-259 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
PIKHPIBO_00971 1.8e-214 yheC HJ YheC/D like ATP-grasp
PIKHPIBO_00972 4.2e-206 yheB S Belongs to the UPF0754 family
PIKHPIBO_00973 4.4e-53 yheA S Belongs to the UPF0342 family
PIKHPIBO_00974 3.2e-198 yhaZ L DNA alkylation repair enzyme
PIKHPIBO_00975 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
PIKHPIBO_00976 1.2e-293 hemZ H coproporphyrinogen III oxidase
PIKHPIBO_00977 7.5e-252 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
PIKHPIBO_00978 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
PIKHPIBO_00979 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
PIKHPIBO_00981 2e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
PIKHPIBO_00982 7.3e-15 S YhzD-like protein
PIKHPIBO_00983 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
PIKHPIBO_00984 4e-205 yhaP CP COG1668 ABC-type Na efflux pump, permease component
PIKHPIBO_00985 1e-237 yhaO L DNA repair exonuclease
PIKHPIBO_00986 0.0 yhaN L AAA domain
PIKHPIBO_00987 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
PIKHPIBO_00988 1.6e-32 yhaL S Sporulation protein YhaL
PIKHPIBO_00989 8e-109 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PIKHPIBO_00990 7e-95 yhaK S Putative zincin peptidase
PIKHPIBO_00991 9.9e-55 yhaI S Protein of unknown function (DUF1878)
PIKHPIBO_00992 8.6e-113 hpr K Negative regulator of protease production and sporulation
PIKHPIBO_00993 6.2e-39 yhaH S YtxH-like protein
PIKHPIBO_00994 2e-17
PIKHPIBO_00995 2.4e-76 trpP S Tryptophan transporter TrpP
PIKHPIBO_00996 9.2e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PIKHPIBO_00997 2.6e-79 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PIKHPIBO_00998 1.1e-135 ecsA V transporter (ATP-binding protein)
PIKHPIBO_00999 1.9e-220 ecsB U ABC transporter
PIKHPIBO_01000 3.6e-123 ecsC S EcsC protein family
PIKHPIBO_01001 1e-223 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PIKHPIBO_01002 5.3e-243 yhfA C membrane
PIKHPIBO_01003 6.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PIKHPIBO_01004 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PIKHPIBO_01005 9.5e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PIKHPIBO_01006 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PIKHPIBO_01007 2e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PIKHPIBO_01008 3.2e-101 yhgD K Transcriptional regulator
PIKHPIBO_01009 2.3e-275 yhgE S YhgE Pip N-terminal domain protein
PIKHPIBO_01010 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PIKHPIBO_01012 2.5e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
PIKHPIBO_01013 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIKHPIBO_01014 7.9e-11 yhfH S YhfH-like protein
PIKHPIBO_01015 1.7e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
PIKHPIBO_01016 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
PIKHPIBO_01017 1.7e-111 yhfK GM NmrA-like family
PIKHPIBO_01018 1.4e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
PIKHPIBO_01019 1.9e-65 yhfM
PIKHPIBO_01020 1.4e-234 yhfN 3.4.24.84 O Peptidase M48
PIKHPIBO_01021 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
PIKHPIBO_01022 5.1e-151 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PIKHPIBO_01023 2.6e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
PIKHPIBO_01024 8.7e-201 vraB 2.3.1.9 I Belongs to the thiolase family
PIKHPIBO_01025 2.3e-278 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
PIKHPIBO_01026 3.5e-89 bioY S BioY family
PIKHPIBO_01027 2.8e-198 hemAT NT chemotaxis protein
PIKHPIBO_01028 4.8e-298 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
PIKHPIBO_01029 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIKHPIBO_01030 1.8e-31 yhzC S IDEAL
PIKHPIBO_01031 1.9e-109 comK K Competence transcription factor
PIKHPIBO_01032 3.9e-68 frataxin S Domain of unknown function (DU1801)
PIKHPIBO_01033 2.4e-65 frataxin S Domain of unknown function (DU1801)
PIKHPIBO_01034 1.5e-91 mepB S MepB protein
PIKHPIBO_01035 2.5e-124 yrpD S Domain of unknown function, YrpD
PIKHPIBO_01036 6e-42 yhjA S Excalibur calcium-binding domain
PIKHPIBO_01037 3.3e-47 S Belongs to the UPF0145 family
PIKHPIBO_01038 1.2e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PIKHPIBO_01039 1.4e-27 yhjC S Protein of unknown function (DUF3311)
PIKHPIBO_01040 5e-60 yhjD
PIKHPIBO_01041 7.7e-109 yhjE S SNARE associated Golgi protein
PIKHPIBO_01042 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
PIKHPIBO_01043 1.5e-275 yhjG CH FAD binding domain
PIKHPIBO_01044 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
PIKHPIBO_01045 4.8e-189 abrB S membrane
PIKHPIBO_01046 2.1e-203 blt EGP Major facilitator Superfamily
PIKHPIBO_01047 2.2e-108 K QacR-like protein, C-terminal region
PIKHPIBO_01048 9.7e-94 yhjR S Rubrerythrin
PIKHPIBO_01049 6.5e-66 ydfS S Protein of unknown function (DUF421)
PIKHPIBO_01050 3.4e-36 ydfS S Protein of unknown function (DUF421)
PIKHPIBO_01051 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
PIKHPIBO_01052 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PIKHPIBO_01053 1.5e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PIKHPIBO_01054 0.0 sbcC L COG0419 ATPase involved in DNA repair
PIKHPIBO_01055 4.2e-49 yisB V COG1403 Restriction endonuclease
PIKHPIBO_01056 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
PIKHPIBO_01057 1.2e-62 gerPE S Spore germination protein GerPE
PIKHPIBO_01058 3.1e-23 gerPD S Spore germination protein
PIKHPIBO_01059 3.5e-61 gerPC S Spore germination protein
PIKHPIBO_01060 6.2e-35 gerPB S cell differentiation
PIKHPIBO_01061 8.4e-34 gerPA S Spore germination protein
PIKHPIBO_01062 5e-07 yisI S Spo0E like sporulation regulatory protein
PIKHPIBO_01063 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PIKHPIBO_01064 1.6e-58 yisL S UPF0344 protein
PIKHPIBO_01065 5.3e-98 yisN S Protein of unknown function (DUF2777)
PIKHPIBO_01066 0.0 asnO 6.3.5.4 E Asparagine synthase
PIKHPIBO_01067 1e-131 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
PIKHPIBO_01068 1.9e-245 yisQ V Mate efflux family protein
PIKHPIBO_01069 1.2e-157 yisR K Transcriptional regulator
PIKHPIBO_01070 2.1e-143 purR K helix_turn _helix lactose operon repressor
PIKHPIBO_01071 1.2e-156 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
PIKHPIBO_01072 1.2e-83 yisT S DinB family
PIKHPIBO_01073 4.6e-69 mcbG S Pentapeptide repeats (9 copies)
PIKHPIBO_01074 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
PIKHPIBO_01075 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PIKHPIBO_01076 1.8e-52 yajQ S Belongs to the UPF0234 family
PIKHPIBO_01077 1.2e-160 cvfB S protein conserved in bacteria
PIKHPIBO_01078 3.4e-172 yufN S ABC transporter substrate-binding protein PnrA-like
PIKHPIBO_01079 7.9e-230 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PIKHPIBO_01080 2.1e-243 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
PIKHPIBO_01082 1.9e-158 yitS S protein conserved in bacteria
PIKHPIBO_01083 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
PIKHPIBO_01084 2.9e-81 ipi S Intracellular proteinase inhibitor
PIKHPIBO_01085 4.4e-26 S Protein of unknown function (DUF3813)
PIKHPIBO_01086 3.5e-07
PIKHPIBO_01087 5.6e-152 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PIKHPIBO_01088 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
PIKHPIBO_01089 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
PIKHPIBO_01090 1.2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
PIKHPIBO_01091 4.6e-272 yitY C D-arabinono-1,4-lactone oxidase
PIKHPIBO_01092 1.2e-89 norB G Major Facilitator Superfamily
PIKHPIBO_01093 5.2e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PIKHPIBO_01094 4.6e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PIKHPIBO_01095 3.5e-135 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
PIKHPIBO_01096 1.7e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PIKHPIBO_01097 3.8e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PIKHPIBO_01098 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
PIKHPIBO_01099 2.7e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PIKHPIBO_01100 1.2e-27 yjzC S YjzC-like protein
PIKHPIBO_01101 1.5e-23 yjzD S Protein of unknown function (DUF2929)
PIKHPIBO_01102 6.4e-139 yjaU I carboxylic ester hydrolase activity
PIKHPIBO_01103 3.6e-105 yjaV
PIKHPIBO_01104 7.2e-166 med S Transcriptional activator protein med
PIKHPIBO_01105 1.1e-26 comZ S ComZ
PIKHPIBO_01106 5.9e-32 yjzB
PIKHPIBO_01107 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PIKHPIBO_01108 2.9e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PIKHPIBO_01109 5.6e-149 yjaZ O Zn-dependent protease
PIKHPIBO_01110 2.8e-182 appD P Belongs to the ABC transporter superfamily
PIKHPIBO_01111 8.5e-187 appF E Belongs to the ABC transporter superfamily
PIKHPIBO_01112 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
PIKHPIBO_01113 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIKHPIBO_01114 1.1e-161 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIKHPIBO_01115 5.5e-146 yjbA S Belongs to the UPF0736 family
PIKHPIBO_01116 1.4e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PIKHPIBO_01117 0.0 oppA E ABC transporter substrate-binding protein
PIKHPIBO_01118 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIKHPIBO_01119 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIKHPIBO_01120 2.7e-202 oppD P Belongs to the ABC transporter superfamily
PIKHPIBO_01121 1.1e-169 oppF E Belongs to the ABC transporter superfamily
PIKHPIBO_01122 8.3e-229 S Putative glycosyl hydrolase domain
PIKHPIBO_01123 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIKHPIBO_01124 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PIKHPIBO_01125 5.6e-110 yjbE P Integral membrane protein TerC family
PIKHPIBO_01126 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PIKHPIBO_01127 1.2e-219 yjbF S Competence protein
PIKHPIBO_01128 0.0 pepF E oligoendopeptidase F
PIKHPIBO_01129 5.8e-19
PIKHPIBO_01130 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PIKHPIBO_01131 4.8e-72 yjbI S Bacterial-like globin
PIKHPIBO_01132 2.1e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PIKHPIBO_01133 2.7e-100 yjbK S protein conserved in bacteria
PIKHPIBO_01134 1.6e-61 yjbL S Belongs to the UPF0738 family
PIKHPIBO_01135 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
PIKHPIBO_01136 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PIKHPIBO_01137 3.5e-163 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PIKHPIBO_01138 1.4e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PIKHPIBO_01139 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PIKHPIBO_01140 1.5e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PIKHPIBO_01141 3.2e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
PIKHPIBO_01142 1.4e-214 thiO 1.4.3.19 E Glycine oxidase
PIKHPIBO_01143 1.4e-30 thiS H Thiamine biosynthesis
PIKHPIBO_01144 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PIKHPIBO_01145 2.9e-190 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PIKHPIBO_01146 8.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PIKHPIBO_01147 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PIKHPIBO_01148 1e-83 yjbX S Spore coat protein
PIKHPIBO_01149 6.7e-83 cotZ S Spore coat protein
PIKHPIBO_01150 4.6e-93 cotY S Spore coat protein Z
PIKHPIBO_01151 4.4e-75 cotX S Spore Coat Protein X and V domain
PIKHPIBO_01152 1.1e-23 cotW
PIKHPIBO_01153 4.2e-57 cotV S Spore Coat Protein X and V domain
PIKHPIBO_01154 2.1e-55 yjcA S Protein of unknown function (DUF1360)
PIKHPIBO_01158 3.8e-38 spoVIF S Stage VI sporulation protein F
PIKHPIBO_01159 0.0 yjcD 3.6.4.12 L DNA helicase
PIKHPIBO_01160 6.7e-35
PIKHPIBO_01161 9.7e-143 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
PIKHPIBO_01162 1.2e-124 S ABC-2 type transporter
PIKHPIBO_01163 4e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
PIKHPIBO_01164 9.4e-36 K SpoVT / AbrB like domain
PIKHPIBO_01166 1.2e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIKHPIBO_01167 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
PIKHPIBO_01168 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
PIKHPIBO_01169 8.7e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PIKHPIBO_01170 7.7e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PIKHPIBO_01172 1.2e-170 L Belongs to the 'phage' integrase family
PIKHPIBO_01175 2.8e-38 S Helix-turn-helix domain
PIKHPIBO_01177 1.5e-36
PIKHPIBO_01182 8.2e-18
PIKHPIBO_01184 4.2e-83
PIKHPIBO_01186 3e-110 L DNA-dependent DNA replication
PIKHPIBO_01188 7.4e-09 yodN
PIKHPIBO_01190 7.3e-139 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
PIKHPIBO_01191 7.3e-133 dnaG L Toprim-like
PIKHPIBO_01192 3.9e-08 K Transcriptional regulator
PIKHPIBO_01193 5.4e-66
PIKHPIBO_01195 3.7e-15
PIKHPIBO_01199 2.5e-45
PIKHPIBO_01200 3.8e-46
PIKHPIBO_01202 1.2e-31
PIKHPIBO_01204 0.0 L 3'-5' exonuclease
PIKHPIBO_01205 1e-77 S RNA ligase
PIKHPIBO_01206 4e-106 2.7.7.7 L EXOIII
PIKHPIBO_01207 5.9e-162
PIKHPIBO_01209 2.6e-31 ruvC 3.1.22.4 L Crossover junction endodeoxyribonuclease RuvC
PIKHPIBO_01215 1.3e-39 nrdI 1.17.4.1 F Belongs to the NrdI family
PIKHPIBO_01216 1e-109 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIKHPIBO_01217 2e-46 S HNH endonuclease
PIKHPIBO_01218 4.8e-181 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIKHPIBO_01220 1.7e-150 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIKHPIBO_01222 7.8e-49 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
PIKHPIBO_01224 2.5e-93 thyX 2.1.1.148 H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
PIKHPIBO_01225 7.4e-34 S protein conserved in bacteria
PIKHPIBO_01227 2.6e-36
PIKHPIBO_01228 2.6e-63 2.7.1.24 H dephospho-CoA kinase activity
PIKHPIBO_01230 9e-143 L the current gene model (or a revised gene model) may contain a
PIKHPIBO_01231 6.2e-48 K Sigma-70, region 4
PIKHPIBO_01232 1.8e-49
PIKHPIBO_01233 1e-134
PIKHPIBO_01234 9.2e-23
PIKHPIBO_01235 2.2e-46
PIKHPIBO_01239 2.8e-116 3.2.1.15 M Right handed beta helix region
PIKHPIBO_01240 4.3e-56 yndL S Replication protein
PIKHPIBO_01241 1.1e-28 K Cro/C1-type HTH DNA-binding domain
PIKHPIBO_01242 4.8e-44 epsH GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
PIKHPIBO_01249 3.7e-67 L Phage integrase family
PIKHPIBO_01250 4e-256 S TIGRFAM Phage
PIKHPIBO_01251 5.4e-29 S Helix-turn-helix of insertion element transposase
PIKHPIBO_01252 1.4e-165
PIKHPIBO_01253 4.4e-80 S Phage minor capsid protein 2
PIKHPIBO_01254 3.6e-19
PIKHPIBO_01255 4.3e-147 S Family of unknown function (DUF5309)
PIKHPIBO_01258 1e-26
PIKHPIBO_01259 2.6e-10
PIKHPIBO_01260 5.1e-29
PIKHPIBO_01261 1.4e-20
PIKHPIBO_01262 7.9e-49 eae N domain, Protein
PIKHPIBO_01263 1e-23
PIKHPIBO_01265 2.6e-164 D phage tail tape measure protein
PIKHPIBO_01266 9.4e-62 S Phage tail protein
PIKHPIBO_01267 1.6e-77 L Prophage endopeptidase tail
PIKHPIBO_01268 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
PIKHPIBO_01269 4.1e-90
PIKHPIBO_01270 2.9e-12
PIKHPIBO_01272 4.5e-29 S BhlA holin family
PIKHPIBO_01273 3.7e-147 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
PIKHPIBO_01274 8.2e-33 S Bacteriophage A118-like holin, Hol118
PIKHPIBO_01276 6.5e-14 S YolD-like protein
PIKHPIBO_01277 3.8e-14
PIKHPIBO_01278 1.5e-13 K Transcriptional regulator
PIKHPIBO_01279 6.9e-99 K Helix-turn-helix domain
PIKHPIBO_01280 7.3e-21
PIKHPIBO_01281 2e-22
PIKHPIBO_01282 7.8e-38
PIKHPIBO_01283 2.9e-29
PIKHPIBO_01284 2e-202 M nucleic acid phosphodiester bond hydrolysis
PIKHPIBO_01286 1.9e-85 yqjL S Alpha beta hydrolase
PIKHPIBO_01288 1.3e-49 FG Scavenger mRNA decapping enzyme C-term binding
PIKHPIBO_01289 2.3e-73 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
PIKHPIBO_01291 2.2e-58 E Glyoxalase-like domain
PIKHPIBO_01292 2.1e-147 bla 3.5.2.6 V beta-lactamase
PIKHPIBO_01293 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
PIKHPIBO_01294 2.7e-250 yfjF EGP Belongs to the major facilitator superfamily
PIKHPIBO_01295 1.4e-81 napB K helix_turn_helix multiple antibiotic resistance protein
PIKHPIBO_01296 5.6e-219 ganA 3.2.1.89 G arabinogalactan
PIKHPIBO_01297 7.6e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PIKHPIBO_01298 6.5e-187 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PIKHPIBO_01299 1.3e-215 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PIKHPIBO_01300 8e-310 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIKHPIBO_01301 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
PIKHPIBO_01302 1.1e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
PIKHPIBO_01303 5.7e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
PIKHPIBO_01304 1.3e-125 5.4.2.6 S Haloacid dehalogenase-like hydrolase
PIKHPIBO_01305 5.9e-34
PIKHPIBO_01306 3.8e-51 K helix_turn_helix multiple antibiotic resistance protein
PIKHPIBO_01307 8.1e-106 yhiD S MgtC SapB transporter
PIKHPIBO_01309 8.3e-21 yjfB S Putative motility protein
PIKHPIBO_01310 2.9e-69 T PhoQ Sensor
PIKHPIBO_01311 4.9e-102 yjgB S Domain of unknown function (DUF4309)
PIKHPIBO_01312 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
PIKHPIBO_01313 7.4e-92 yjgD S Protein of unknown function (DUF1641)
PIKHPIBO_01314 7.2e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
PIKHPIBO_01315 3e-223 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PIKHPIBO_01316 6.8e-29
PIKHPIBO_01317 7.3e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PIKHPIBO_01318 1.5e-122 ybbM S transport system, permease component
PIKHPIBO_01319 1.9e-130 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
PIKHPIBO_01320 1.1e-178 yjlA EG Putative multidrug resistance efflux transporter
PIKHPIBO_01321 1.8e-92 yjlB S Cupin domain
PIKHPIBO_01322 7e-66 yjlC S Protein of unknown function (DUF1641)
PIKHPIBO_01323 4.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
PIKHPIBO_01324 3.3e-277 uxaC 5.3.1.12 G glucuronate isomerase
PIKHPIBO_01325 3.9e-254 yjmB G symporter YjmB
PIKHPIBO_01326 1.7e-182 exuR K transcriptional
PIKHPIBO_01327 3.7e-276 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
PIKHPIBO_01328 2.4e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
PIKHPIBO_01329 3.9e-131 MA20_18170 S membrane transporter protein
PIKHPIBO_01330 3.1e-78 yjoA S DinB family
PIKHPIBO_01331 1.4e-214 S response regulator aspartate phosphatase
PIKHPIBO_01333 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PIKHPIBO_01334 4.7e-61 yjqA S Bacterial PH domain
PIKHPIBO_01335 1.8e-110 yjqB S phage-related replication protein
PIKHPIBO_01336 1.1e-109 xkdA E IrrE N-terminal-like domain
PIKHPIBO_01337 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
PIKHPIBO_01339 8.5e-153 xkdC L Bacterial dnaA protein
PIKHPIBO_01342 2e-10 yqaO S Phage-like element PBSX protein XtrA
PIKHPIBO_01343 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PIKHPIBO_01344 6.1e-111 xtmA L phage terminase small subunit
PIKHPIBO_01345 6.1e-209 xtmB S phage terminase, large subunit
PIKHPIBO_01346 6e-242 yqbA S portal protein
PIKHPIBO_01347 5.7e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
PIKHPIBO_01348 1e-157 xkdG S Phage capsid family
PIKHPIBO_01349 2.8e-45 yqbG S Protein of unknown function (DUF3199)
PIKHPIBO_01350 5.5e-43 yqbH S Domain of unknown function (DUF3599)
PIKHPIBO_01351 3.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
PIKHPIBO_01352 8.3e-57 xkdJ
PIKHPIBO_01353 3.1e-14
PIKHPIBO_01354 1e-225 xkdK S Phage tail sheath C-terminal domain
PIKHPIBO_01355 2e-74 xkdM S Phage tail tube protein
PIKHPIBO_01356 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
PIKHPIBO_01357 3.4e-19
PIKHPIBO_01358 7.6e-199 xkdO L Transglycosylase SLT domain
PIKHPIBO_01359 1.5e-110 xkdP S Lysin motif
PIKHPIBO_01360 7.2e-162 xkdQ 3.2.1.96 G NLP P60 protein
PIKHPIBO_01361 1.2e-31 xkdR S Protein of unknown function (DUF2577)
PIKHPIBO_01362 1e-56 xkdS S Protein of unknown function (DUF2634)
PIKHPIBO_01363 1.5e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PIKHPIBO_01364 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
PIKHPIBO_01365 1.2e-26
PIKHPIBO_01366 5.8e-92
PIKHPIBO_01368 6.5e-30 xkdX
PIKHPIBO_01369 3.6e-137 xepA
PIKHPIBO_01370 8.7e-38 xhlA S Haemolysin XhlA
PIKHPIBO_01371 1.3e-38 xhlB S SPP1 phage holin
PIKHPIBO_01372 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PIKHPIBO_01373 1.9e-22 spoIISB S Stage II sporulation protein SB
PIKHPIBO_01374 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
PIKHPIBO_01375 5.8e-175 pit P phosphate transporter
PIKHPIBO_01376 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
PIKHPIBO_01377 5e-243 steT E amino acid
PIKHPIBO_01378 4.8e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
PIKHPIBO_01379 1.3e-301 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PIKHPIBO_01380 1.2e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PIKHPIBO_01382 1.8e-203 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PIKHPIBO_01383 2.7e-280 yubD P Major Facilitator Superfamily
PIKHPIBO_01385 2.5e-155 dppA E D-aminopeptidase
PIKHPIBO_01386 1.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIKHPIBO_01387 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PIKHPIBO_01388 4.5e-191 dppD P Belongs to the ABC transporter superfamily
PIKHPIBO_01389 0.0 dppE E ABC transporter substrate-binding protein
PIKHPIBO_01390 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
PIKHPIBO_01391 4.1e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
PIKHPIBO_01392 1.1e-169 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PIKHPIBO_01393 9.6e-183 ykfD E Belongs to the ABC transporter superfamily
PIKHPIBO_01394 1.3e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
PIKHPIBO_01395 1.9e-158 ykgA E Amidinotransferase
PIKHPIBO_01396 1.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
PIKHPIBO_01397 2.6e-100 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PIKHPIBO_01398 2.7e-52 ykkC P Multidrug resistance protein
PIKHPIBO_01399 3.4e-49 ykkD P Multidrug resistance protein
PIKHPIBO_01400 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
PIKHPIBO_01401 2.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PIKHPIBO_01402 4.8e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PIKHPIBO_01403 1.3e-70 ohrA O Organic hydroperoxide resistance protein
PIKHPIBO_01404 1.5e-86 ohrR K COG1846 Transcriptional regulators
PIKHPIBO_01405 9.3e-71 ohrB O Organic hydroperoxide resistance protein
PIKHPIBO_01406 9e-56 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PIKHPIBO_01408 2.2e-215 M Glycosyl transferase family 2
PIKHPIBO_01409 6.1e-112 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
PIKHPIBO_01410 5.5e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
PIKHPIBO_01411 2.6e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PIKHPIBO_01412 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PIKHPIBO_01413 3.8e-176 isp O Belongs to the peptidase S8 family
PIKHPIBO_01414 2.5e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PIKHPIBO_01415 8.7e-131 ykoC P Cobalt transport protein
PIKHPIBO_01416 4.8e-304 P ABC transporter, ATP-binding protein
PIKHPIBO_01417 3.4e-98 ykoE S ABC-type cobalt transport system, permease component
PIKHPIBO_01418 1e-245 ydhD M Glycosyl hydrolase
PIKHPIBO_01420 2.2e-238 mgtE P Acts as a magnesium transporter
PIKHPIBO_01421 5.4e-53 tnrA K transcriptional
PIKHPIBO_01422 1.9e-16
PIKHPIBO_01423 3.1e-26 ykoL
PIKHPIBO_01424 1.1e-80 ykoM K transcriptional
PIKHPIBO_01425 3.7e-99 ykoP G polysaccharide deacetylase
PIKHPIBO_01426 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
PIKHPIBO_01427 1.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PIKHPIBO_01428 2.7e-100 ykoX S membrane-associated protein
PIKHPIBO_01429 5.1e-134 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PIKHPIBO_01430 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIKHPIBO_01431 3.1e-119 rsgI S Anti-sigma factor N-terminus
PIKHPIBO_01432 2.5e-26 sspD S small acid-soluble spore protein
PIKHPIBO_01433 7.8e-126 ykrK S Domain of unknown function (DUF1836)
PIKHPIBO_01434 4.1e-156 htpX O Belongs to the peptidase M48B family
PIKHPIBO_01435 1.4e-240 ktrB P COG0168 Trk-type K transport systems, membrane components
PIKHPIBO_01436 1.5e-113 ydfR S Protein of unknown function (DUF421)
PIKHPIBO_01437 7.9e-24 ykzE
PIKHPIBO_01438 2.5e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
PIKHPIBO_01439 0.0 kinE 2.7.13.3 T Histidine kinase
PIKHPIBO_01440 1e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PIKHPIBO_01442 6.3e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PIKHPIBO_01443 2.2e-226 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PIKHPIBO_01444 2.5e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PIKHPIBO_01445 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
PIKHPIBO_01446 2.5e-225 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
PIKHPIBO_01447 3.5e-134 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PIKHPIBO_01448 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
PIKHPIBO_01449 6.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PIKHPIBO_01450 3.4e-10 S Spo0E like sporulation regulatory protein
PIKHPIBO_01451 2.1e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
PIKHPIBO_01452 5.5e-77 ykvE K transcriptional
PIKHPIBO_01453 4.6e-127 motB N Flagellar motor protein
PIKHPIBO_01454 1.1e-136 motA N flagellar motor
PIKHPIBO_01455 0.0 clpE O Belongs to the ClpA ClpB family
PIKHPIBO_01456 3.2e-184 ykvI S membrane
PIKHPIBO_01457 8.4e-191
PIKHPIBO_01458 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PIKHPIBO_01459 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
PIKHPIBO_01460 3.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PIKHPIBO_01461 5e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PIKHPIBO_01462 1e-60 ykvN K HxlR-like helix-turn-helix
PIKHPIBO_01463 1.3e-131 IQ Enoyl-(Acyl carrier protein) reductase
PIKHPIBO_01464 2.9e-30 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PIKHPIBO_01465 3.3e-152 3.6.4.12 L Putative ATP-dependent DNA helicase recG C-terminal
PIKHPIBO_01466 3.5e-45 ykvR S Protein of unknown function (DUF3219)
PIKHPIBO_01467 7.8e-25 ykvS S protein conserved in bacteria
PIKHPIBO_01468 7.9e-28
PIKHPIBO_01469 2.4e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
PIKHPIBO_01470 3.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIKHPIBO_01471 1.7e-87 stoA CO thiol-disulfide
PIKHPIBO_01472 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PIKHPIBO_01473 4.8e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
PIKHPIBO_01475 2.3e-176 ykvZ 5.1.1.1 K Transcriptional regulator
PIKHPIBO_01476 5.1e-156 glcT K antiterminator
PIKHPIBO_01477 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PIKHPIBO_01478 2.1e-39 ptsH G phosphocarrier protein HPr
PIKHPIBO_01479 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PIKHPIBO_01480 6.1e-38 splA S Transcriptional regulator
PIKHPIBO_01481 7.2e-189 splB 4.1.99.14 L Spore photoproduct lyase
PIKHPIBO_01482 1.9e-262 mcpC NT chemotaxis protein
PIKHPIBO_01483 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PIKHPIBO_01484 8e-64
PIKHPIBO_01485 1.5e-114 ykwD J protein with SCP PR1 domains
PIKHPIBO_01486 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
PIKHPIBO_01487 1.5e-144 pilS 2.7.13.3 T PAS fold
PIKHPIBO_01488 1.1e-154 pilS 2.7.13.3 T Histidine kinase
PIKHPIBO_01489 3.9e-215 patA 2.6.1.1 E Aminotransferase
PIKHPIBO_01490 2.3e-09
PIKHPIBO_01491 2.6e-166 cheV 2.7.13.3 T Chemotaxis protein CheV
PIKHPIBO_01492 3.2e-83 ykyB S YkyB-like protein
PIKHPIBO_01493 8.7e-240 ykuC EGP Major facilitator Superfamily
PIKHPIBO_01494 1.7e-87 ykuD S protein conserved in bacteria
PIKHPIBO_01495 2.6e-155 ykuE S Metallophosphoesterase
PIKHPIBO_01496 3.8e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIKHPIBO_01498 1.7e-232 ykuI T Diguanylate phosphodiesterase
PIKHPIBO_01499 3.9e-37 ykuJ S protein conserved in bacteria
PIKHPIBO_01500 4.9e-93 ykuK S Ribonuclease H-like
PIKHPIBO_01501 2.5e-26 ykzF S Antirepressor AbbA
PIKHPIBO_01502 1e-75 ykuL S CBS domain
PIKHPIBO_01503 4.6e-168 ccpC K Transcriptional regulator
PIKHPIBO_01504 1.3e-89 fld C Flavodoxin
PIKHPIBO_01505 5.9e-171 ykuO
PIKHPIBO_01506 1e-78 fld C Flavodoxin
PIKHPIBO_01507 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PIKHPIBO_01508 1.5e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PIKHPIBO_01509 4.8e-38 ykuS S Belongs to the UPF0180 family
PIKHPIBO_01510 1.9e-139 ykuT M Mechanosensitive ion channel
PIKHPIBO_01511 2.3e-78 ykuV CO thiol-disulfide
PIKHPIBO_01512 4.5e-98 rok K Repressor of ComK
PIKHPIBO_01513 3.6e-161 yknT
PIKHPIBO_01514 8.2e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PIKHPIBO_01515 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PIKHPIBO_01516 1.3e-243 moeA 2.10.1.1 H molybdopterin
PIKHPIBO_01517 3.8e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
PIKHPIBO_01518 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
PIKHPIBO_01519 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PIKHPIBO_01520 2.1e-107 yknW S Yip1 domain
PIKHPIBO_01521 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PIKHPIBO_01522 6.1e-123 macB V ABC transporter, ATP-binding protein
PIKHPIBO_01523 3.9e-210 yknZ V ABC transporter (permease)
PIKHPIBO_01524 4.6e-132 fruR K Transcriptional regulator
PIKHPIBO_01525 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
PIKHPIBO_01526 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PIKHPIBO_01527 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PIKHPIBO_01528 9.8e-37 ykoA
PIKHPIBO_01529 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PIKHPIBO_01530 2.9e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PIKHPIBO_01531 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PIKHPIBO_01532 5.5e-12 S Uncharacterized protein YkpC
PIKHPIBO_01533 6.9e-184 mreB D Rod-share determining protein MreBH
PIKHPIBO_01534 2.1e-45 abrB K of stationary sporulation gene expression
PIKHPIBO_01535 3.7e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
PIKHPIBO_01536 5.9e-149 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
PIKHPIBO_01537 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
PIKHPIBO_01538 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PIKHPIBO_01539 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIKHPIBO_01540 8.2e-31 ykzG S Belongs to the UPF0356 family
PIKHPIBO_01541 3.9e-147 ykrA S hydrolases of the HAD superfamily
PIKHPIBO_01542 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PIKHPIBO_01544 6.5e-103 recN L Putative cell-wall binding lipoprotein
PIKHPIBO_01545 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PIKHPIBO_01546 0.0 Q Polyketide synthase of type I
PIKHPIBO_01547 0.0 Q polyketide synthase
PIKHPIBO_01548 0.0 Q Polyketide synthase of type I
PIKHPIBO_01549 0.0 Q Polyketide synthase of type I
PIKHPIBO_01550 0.0 Q Polyketide synthase of type I
PIKHPIBO_01551 0.0 Q Polyketide synthase of type I
PIKHPIBO_01552 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
PIKHPIBO_01553 1.3e-209 V Beta-lactamase
PIKHPIBO_01554 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PIKHPIBO_01555 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PIKHPIBO_01556 2.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PIKHPIBO_01557 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PIKHPIBO_01558 4.7e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
PIKHPIBO_01559 5.3e-139 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
PIKHPIBO_01560 3.5e-277 speA 4.1.1.19 E Arginine
PIKHPIBO_01561 1.6e-42 yktA S Belongs to the UPF0223 family
PIKHPIBO_01562 4.9e-119 yktB S Belongs to the UPF0637 family
PIKHPIBO_01563 6.3e-24 ykzI
PIKHPIBO_01564 2.3e-150 suhB 3.1.3.25 G Inositol monophosphatase
PIKHPIBO_01565 1.5e-82 ykzC S Acetyltransferase (GNAT) family
PIKHPIBO_01566 1.9e-294 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
PIKHPIBO_01567 2.3e-188 ylaA
PIKHPIBO_01568 1.1e-43 ylaB
PIKHPIBO_01569 1.7e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
PIKHPIBO_01570 2.8e-13 sigC S Putative zinc-finger
PIKHPIBO_01571 3.7e-39 ylaE
PIKHPIBO_01572 6.7e-24 S Family of unknown function (DUF5325)
PIKHPIBO_01573 0.0 typA T GTP-binding protein TypA
PIKHPIBO_01574 1.3e-48 ylaH S YlaH-like protein
PIKHPIBO_01575 1e-33 ylaI S protein conserved in bacteria
PIKHPIBO_01576 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PIKHPIBO_01577 3.2e-245 phoH T ATPase related to phosphate starvation-inducible protein PhoH
PIKHPIBO_01578 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PIKHPIBO_01579 2.1e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
PIKHPIBO_01580 8.7e-44 ylaN S Belongs to the UPF0358 family
PIKHPIBO_01581 5.5e-212 ftsW D Belongs to the SEDS family
PIKHPIBO_01582 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PIKHPIBO_01583 3.3e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PIKHPIBO_01584 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PIKHPIBO_01585 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PIKHPIBO_01586 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PIKHPIBO_01587 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PIKHPIBO_01588 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PIKHPIBO_01589 3.7e-165 ctaG S cytochrome c oxidase
PIKHPIBO_01590 8.5e-60 ylbA S YugN-like family
PIKHPIBO_01591 6.3e-73 ylbB T COG0517 FOG CBS domain
PIKHPIBO_01592 1.7e-198 ylbC S protein with SCP PR1 domains
PIKHPIBO_01593 2.5e-55 ylbD S Putative coat protein
PIKHPIBO_01594 8.8e-37 ylbE S YlbE-like protein
PIKHPIBO_01595 1.2e-71 ylbF S Belongs to the UPF0342 family
PIKHPIBO_01596 7.2e-43 ylbG S UPF0298 protein
PIKHPIBO_01598 4.2e-89 rsmD 2.1.1.171 L Methyltransferase
PIKHPIBO_01599 7.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PIKHPIBO_01600 4.9e-216 ylbJ S Sporulation integral membrane protein YlbJ
PIKHPIBO_01601 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
PIKHPIBO_01602 5.5e-189 ylbL T Belongs to the peptidase S16 family
PIKHPIBO_01603 2.9e-09 yqgA
PIKHPIBO_01604 1.6e-121 ylbM S Belongs to the UPF0348 family
PIKHPIBO_01605 8.7e-90 yceD S metal-binding, possibly nucleic acid-binding protein
PIKHPIBO_01606 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PIKHPIBO_01607 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PIKHPIBO_01608 3.1e-89 ylbP K n-acetyltransferase
PIKHPIBO_01609 1.6e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PIKHPIBO_01610 8.7e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PIKHPIBO_01611 8.9e-78 mraZ K Belongs to the MraZ family
PIKHPIBO_01612 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PIKHPIBO_01613 1.1e-51 ftsL D Essential cell division protein
PIKHPIBO_01614 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PIKHPIBO_01615 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
PIKHPIBO_01616 7.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PIKHPIBO_01617 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PIKHPIBO_01618 1.3e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PIKHPIBO_01619 2.2e-185 spoVE D Belongs to the SEDS family
PIKHPIBO_01620 3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PIKHPIBO_01621 3.7e-168 murB 1.3.1.98 M cell wall formation
PIKHPIBO_01622 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PIKHPIBO_01623 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PIKHPIBO_01624 5.8e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PIKHPIBO_01625 0.0 bpr O COG1404 Subtilisin-like serine proteases
PIKHPIBO_01626 8.9e-162 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PIKHPIBO_01627 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIKHPIBO_01628 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIKHPIBO_01629 4.5e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PIKHPIBO_01630 1.9e-255 argE 3.5.1.16 E Acetylornithine deacetylase
PIKHPIBO_01631 2.2e-38 ylmC S sporulation protein
PIKHPIBO_01632 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
PIKHPIBO_01633 6.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PIKHPIBO_01634 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PIKHPIBO_01635 5.2e-41 yggT S membrane
PIKHPIBO_01636 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
PIKHPIBO_01637 8.9e-68 divIVA D Cell division initiation protein
PIKHPIBO_01638 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PIKHPIBO_01639 1.6e-61 dksA T COG1734 DnaK suppressor protein
PIKHPIBO_01640 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PIKHPIBO_01641 1.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PIKHPIBO_01642 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIKHPIBO_01643 2.3e-232 pyrP F Xanthine uracil
PIKHPIBO_01644 4.8e-168 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PIKHPIBO_01645 1.5e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PIKHPIBO_01646 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PIKHPIBO_01647 0.0 carB 6.3.5.5 F Belongs to the CarB family
PIKHPIBO_01648 1.9e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PIKHPIBO_01649 6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PIKHPIBO_01650 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PIKHPIBO_01651 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PIKHPIBO_01653 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
PIKHPIBO_01654 1.8e-179 cysP P phosphate transporter
PIKHPIBO_01655 3.8e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
PIKHPIBO_01656 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
PIKHPIBO_01657 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
PIKHPIBO_01658 1.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
PIKHPIBO_01659 2e-80 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
PIKHPIBO_01660 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PIKHPIBO_01661 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
PIKHPIBO_01662 1e-154 yloC S stress-induced protein
PIKHPIBO_01663 1.5e-40 ylzA S Belongs to the UPF0296 family
PIKHPIBO_01664 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PIKHPIBO_01665 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PIKHPIBO_01666 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PIKHPIBO_01667 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PIKHPIBO_01668 8.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PIKHPIBO_01669 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PIKHPIBO_01670 2.3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PIKHPIBO_01671 2.6e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PIKHPIBO_01672 3.9e-139 stp 3.1.3.16 T phosphatase
PIKHPIBO_01673 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PIKHPIBO_01674 8.2e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PIKHPIBO_01675 2.3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PIKHPIBO_01676 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
PIKHPIBO_01677 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PIKHPIBO_01678 1.2e-58 asp S protein conserved in bacteria
PIKHPIBO_01679 3.8e-304 yloV S kinase related to dihydroxyacetone kinase
PIKHPIBO_01680 2.1e-117 sdaAB 4.3.1.17 E L-serine dehydratase
PIKHPIBO_01681 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
PIKHPIBO_01682 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PIKHPIBO_01683 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PIKHPIBO_01684 6.2e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PIKHPIBO_01685 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PIKHPIBO_01686 4.6e-129 IQ reductase
PIKHPIBO_01687 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIKHPIBO_01688 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PIKHPIBO_01689 0.0 smc D Required for chromosome condensation and partitioning
PIKHPIBO_01690 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PIKHPIBO_01691 2.3e-139 S Phosphotransferase enzyme family
PIKHPIBO_01692 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PIKHPIBO_01693 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PIKHPIBO_01694 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PIKHPIBO_01695 1.7e-35 ylqC S Belongs to the UPF0109 family
PIKHPIBO_01696 1.3e-61 ylqD S YlqD protein
PIKHPIBO_01697 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PIKHPIBO_01698 5.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PIKHPIBO_01699 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PIKHPIBO_01700 6.4e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PIKHPIBO_01701 1.2e-124 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIKHPIBO_01702 5.9e-305 ylqG
PIKHPIBO_01703 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
PIKHPIBO_01704 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PIKHPIBO_01705 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PIKHPIBO_01706 1.6e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
PIKHPIBO_01707 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PIKHPIBO_01708 4.8e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PIKHPIBO_01709 7.2e-172 xerC L tyrosine recombinase XerC
PIKHPIBO_01710 2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PIKHPIBO_01711 1.1e-232 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PIKHPIBO_01712 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PIKHPIBO_01713 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PIKHPIBO_01714 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
PIKHPIBO_01715 2.5e-31 fliE N Flagellar hook-basal body
PIKHPIBO_01716 2.3e-258 fliF N The M ring may be actively involved in energy transduction
PIKHPIBO_01717 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PIKHPIBO_01718 4.3e-90 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
PIKHPIBO_01719 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PIKHPIBO_01720 4.5e-71 fliJ N Flagellar biosynthesis chaperone
PIKHPIBO_01721 1.3e-47 ylxF S MgtE intracellular N domain
PIKHPIBO_01722 2.6e-199 fliK N Flagellar hook-length control protein
PIKHPIBO_01723 1.4e-72 flgD N Flagellar basal body rod modification protein
PIKHPIBO_01724 4e-139 flgG N Flagellar basal body rod
PIKHPIBO_01725 6e-57 fliL N Controls the rotational direction of flagella during chemotaxis
PIKHPIBO_01726 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PIKHPIBO_01727 8e-189 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PIKHPIBO_01728 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
PIKHPIBO_01729 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
PIKHPIBO_01730 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
PIKHPIBO_01731 2e-37 fliQ N Role in flagellar biosynthesis
PIKHPIBO_01732 8.9e-131 fliR N Flagellar biosynthetic protein FliR
PIKHPIBO_01733 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PIKHPIBO_01734 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PIKHPIBO_01735 6.1e-194 flhF N Flagellar biosynthesis regulator FlhF
PIKHPIBO_01736 4.5e-155 flhG D Belongs to the ParA family
PIKHPIBO_01737 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PIKHPIBO_01738 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
PIKHPIBO_01739 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
PIKHPIBO_01740 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PIKHPIBO_01741 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PIKHPIBO_01742 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIKHPIBO_01743 5.3e-54 ylxL
PIKHPIBO_01744 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
PIKHPIBO_01745 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PIKHPIBO_01746 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PIKHPIBO_01747 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PIKHPIBO_01748 1.1e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PIKHPIBO_01749 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
PIKHPIBO_01750 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PIKHPIBO_01751 5.9e-233 rasP M zinc metalloprotease
PIKHPIBO_01752 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PIKHPIBO_01753 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIKHPIBO_01754 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
PIKHPIBO_01755 5.4e-206 nusA K Participates in both transcription termination and antitermination
PIKHPIBO_01756 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
PIKHPIBO_01757 1.8e-47 ylxQ J ribosomal protein
PIKHPIBO_01758 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PIKHPIBO_01759 3.9e-44 ylxP S protein conserved in bacteria
PIKHPIBO_01760 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PIKHPIBO_01761 1.6e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PIKHPIBO_01762 2.3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PIKHPIBO_01763 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PIKHPIBO_01764 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PIKHPIBO_01765 1.3e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
PIKHPIBO_01766 1.4e-234 pepR S Belongs to the peptidase M16 family
PIKHPIBO_01767 2.6e-42 ymxH S YlmC YmxH family
PIKHPIBO_01768 3.6e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
PIKHPIBO_01769 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PIKHPIBO_01770 1.9e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PIKHPIBO_01771 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
PIKHPIBO_01772 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PIKHPIBO_01773 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIKHPIBO_01774 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
PIKHPIBO_01775 1.1e-30 S YlzJ-like protein
PIKHPIBO_01776 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PIKHPIBO_01777 1.8e-133 ymfC K Transcriptional regulator
PIKHPIBO_01778 3.2e-229 ymfD EGP Major facilitator Superfamily
PIKHPIBO_01779 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
PIKHPIBO_01780 0.0 ydgH S drug exporters of the RND superfamily
PIKHPIBO_01781 1.2e-238 ymfF S Peptidase M16
PIKHPIBO_01782 3.4e-244 ymfH S zinc protease
PIKHPIBO_01783 1.3e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PIKHPIBO_01784 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
PIKHPIBO_01785 1e-142 ymfK S Protein of unknown function (DUF3388)
PIKHPIBO_01786 4.2e-124 ymfM S protein conserved in bacteria
PIKHPIBO_01787 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PIKHPIBO_01788 2.7e-230 cinA 3.5.1.42 S Belongs to the CinA family
PIKHPIBO_01789 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PIKHPIBO_01790 8.3e-181 pbpX V Beta-lactamase
PIKHPIBO_01791 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
PIKHPIBO_01792 4.9e-153 ymdB S protein conserved in bacteria
PIKHPIBO_01793 1.2e-36 spoVS S Stage V sporulation protein S
PIKHPIBO_01794 6.9e-195 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
PIKHPIBO_01795 3.9e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PIKHPIBO_01796 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PIKHPIBO_01797 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PIKHPIBO_01798 1.7e-88 cotE S Spore coat protein
PIKHPIBO_01799 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PIKHPIBO_01800 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PIKHPIBO_01803 1.8e-117
PIKHPIBO_01805 2.2e-31
PIKHPIBO_01807 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
PIKHPIBO_01808 4.9e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PIKHPIBO_01809 8.7e-184 pksD Q Acyl transferase domain
PIKHPIBO_01810 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PIKHPIBO_01811 1.9e-34 acpK IQ Phosphopantetheine attachment site
PIKHPIBO_01812 3.7e-243 pksG 2.3.3.10 I synthase
PIKHPIBO_01813 5.9e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
PIKHPIBO_01814 8.5e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
PIKHPIBO_01815 0.0 rhiB IQ polyketide synthase
PIKHPIBO_01816 0.0 Q Polyketide synthase of type I
PIKHPIBO_01817 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
PIKHPIBO_01818 0.0 dhbF IQ polyketide synthase
PIKHPIBO_01819 0.0 pks13 HQ Beta-ketoacyl synthase
PIKHPIBO_01820 3.4e-230 cypA C Cytochrome P450
PIKHPIBO_01821 4.9e-78 nucB M Deoxyribonuclease NucA/NucB
PIKHPIBO_01822 3.6e-118 yoaK S Membrane
PIKHPIBO_01823 1.4e-62 ymzB
PIKHPIBO_01824 3.4e-255 aprX O Belongs to the peptidase S8 family
PIKHPIBO_01826 7.8e-126 ymaC S Replication protein
PIKHPIBO_01827 6e-79 ymaD O redox protein, regulator of disulfide bond formation
PIKHPIBO_01828 1.2e-53 ebrB P Small Multidrug Resistance protein
PIKHPIBO_01829 3.1e-48 ebrA P Small Multidrug Resistance protein
PIKHPIBO_01831 1.4e-47 ymaF S YmaF family
PIKHPIBO_01832 2.5e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PIKHPIBO_01833 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PIKHPIBO_01834 9.4e-43
PIKHPIBO_01835 1.8e-20 ymzA
PIKHPIBO_01836 1.7e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
PIKHPIBO_01837 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIKHPIBO_01838 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIKHPIBO_01839 2.4e-110 ymaB S MutT family
PIKHPIBO_01840 1.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PIKHPIBO_01841 1.3e-176 spoVK O stage V sporulation protein K
PIKHPIBO_01842 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PIKHPIBO_01843 5.3e-242 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PIKHPIBO_01844 1.6e-67 glnR K transcriptional
PIKHPIBO_01845 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
PIKHPIBO_01846 1.7e-30
PIKHPIBO_01847 3.1e-31 S nuclease activity
PIKHPIBO_01850 5.8e-22
PIKHPIBO_01851 3.2e-21
PIKHPIBO_01853 3.5e-210 mrjp G Major royal jelly protein
PIKHPIBO_01855 3.7e-252 xynT G MFS/sugar transport protein
PIKHPIBO_01856 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
PIKHPIBO_01857 3.3e-214 xylR GK ROK family
PIKHPIBO_01858 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
PIKHPIBO_01859 1.1e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
PIKHPIBO_01860 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
PIKHPIBO_01863 2e-16
PIKHPIBO_01864 1.3e-120 K WYL domain
PIKHPIBO_01865 1.3e-66 S DinB family
PIKHPIBO_01866 9.7e-186 adhP 1.1.1.1 C alcohol dehydrogenase
PIKHPIBO_01868 1.9e-16
PIKHPIBO_01869 5.6e-19 yoaW
PIKHPIBO_01871 5.2e-113 yoaP 3.1.3.18 K YoaP-like
PIKHPIBO_01872 8.5e-286 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PIKHPIBO_01873 1.4e-51 S SMI1-KNR4 cell-wall
PIKHPIBO_01874 1.8e-94 yokK S SMI1 / KNR4 family
PIKHPIBO_01875 8e-63 S Acetyltransferase (GNAT) domain
PIKHPIBO_01876 5e-22
PIKHPIBO_01878 4.5e-35
PIKHPIBO_01880 1.5e-117 ynaE S Domain of unknown function (DUF3885)
PIKHPIBO_01881 1.6e-202 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIKHPIBO_01882 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
PIKHPIBO_01884 4.6e-94 yvgO
PIKHPIBO_01886 0.0 yobO M Pectate lyase superfamily protein
PIKHPIBO_01887 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
PIKHPIBO_01888 1.3e-143 yndL S Replication protein
PIKHPIBO_01890 8e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
PIKHPIBO_01891 3.2e-72 yndM S Protein of unknown function (DUF2512)
PIKHPIBO_01892 7.8e-12 yoaW
PIKHPIBO_01893 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PIKHPIBO_01894 1.4e-50 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PIKHPIBO_01895 3.5e-112 yneB L resolvase
PIKHPIBO_01896 9.8e-33 ynzC S UPF0291 protein
PIKHPIBO_01897 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PIKHPIBO_01898 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
PIKHPIBO_01899 2.3e-28 yneF S UPF0154 protein
PIKHPIBO_01900 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
PIKHPIBO_01901 5.1e-125 ccdA O cytochrome c biogenesis protein
PIKHPIBO_01902 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
PIKHPIBO_01903 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
PIKHPIBO_01904 8.5e-75 yneK S Protein of unknown function (DUF2621)
PIKHPIBO_01905 2.1e-61 hspX O Spore coat protein
PIKHPIBO_01906 2.3e-19 sspP S Belongs to the SspP family
PIKHPIBO_01907 7.5e-15 sspO S Belongs to the SspO family
PIKHPIBO_01908 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PIKHPIBO_01909 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PIKHPIBO_01911 2.7e-33 tlp S Belongs to the Tlp family
PIKHPIBO_01912 8.3e-75 yneP S Thioesterase-like superfamily
PIKHPIBO_01913 3.7e-53 yneQ
PIKHPIBO_01914 1.3e-50 yneR S Belongs to the HesB IscA family
PIKHPIBO_01915 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIKHPIBO_01916 1.5e-68 yccU S CoA-binding protein
PIKHPIBO_01917 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIKHPIBO_01918 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIKHPIBO_01919 6e-13
PIKHPIBO_01920 5.1e-41 ynfC
PIKHPIBO_01921 1.6e-250 agcS E Sodium alanine symporter
PIKHPIBO_01922 5.2e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
PIKHPIBO_01923 6.9e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
PIKHPIBO_01924 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
PIKHPIBO_01925 4.1e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
PIKHPIBO_01926 4.6e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PIKHPIBO_01927 1.7e-182 kdgR_1 K transcriptional
PIKHPIBO_01928 1.6e-222 exuT G Sugar (and other) transporter
PIKHPIBO_01929 4.4e-157 yndG S DoxX-like family
PIKHPIBO_01930 2e-77 yndH S Domain of unknown function (DUF4166)
PIKHPIBO_01931 1.2e-302 yndJ S YndJ-like protein
PIKHPIBO_01932 6.4e-86
PIKHPIBO_01933 1.5e-64 V ABC transporter
PIKHPIBO_01935 1.4e-11
PIKHPIBO_01936 4.6e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
PIKHPIBO_01937 2.8e-51 S Domain of unknown function (DUF4870)
PIKHPIBO_01938 2.4e-235 T PhoQ Sensor
PIKHPIBO_01939 9.9e-129 T Transcriptional regulatory protein, C terminal
PIKHPIBO_01940 1.1e-252 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
PIKHPIBO_01941 2.7e-288 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
PIKHPIBO_01942 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_01943 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_01944 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_01945 4.3e-225 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PIKHPIBO_01946 3.4e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PIKHPIBO_01947 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PIKHPIBO_01948 2.9e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PIKHPIBO_01949 1.3e-252 yxjC EG COG2610 H gluconate symporter and related permeases
PIKHPIBO_01950 3.4e-222 bioI 1.14.14.46 C Cytochrome P450
PIKHPIBO_01951 2.8e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PIKHPIBO_01952 1.4e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PIKHPIBO_01953 1.5e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PIKHPIBO_01954 1.9e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
PIKHPIBO_01955 5.9e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
PIKHPIBO_01956 1.9e-71 yngA S membrane
PIKHPIBO_01957 1e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PIKHPIBO_01958 3.2e-104 yngC S SNARE associated Golgi protein
PIKHPIBO_01959 2.8e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PIKHPIBO_01960 8.9e-139 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
PIKHPIBO_01961 2.8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
PIKHPIBO_01962 3.2e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
PIKHPIBO_01963 2.1e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
PIKHPIBO_01964 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PIKHPIBO_01965 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
PIKHPIBO_01966 1.5e-302 yngK T Glycosyl hydrolase-like 10
PIKHPIBO_01967 4.1e-65 yngL S Protein of unknown function (DUF1360)
PIKHPIBO_01968 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
PIKHPIBO_01969 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_01970 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_01971 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_01972 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_01973 5.2e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
PIKHPIBO_01974 1.5e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
PIKHPIBO_01975 7.9e-247 yoeA V MATE efflux family protein
PIKHPIBO_01976 3.8e-96 yoeB S IseA DL-endopeptidase inhibitor
PIKHPIBO_01978 3.5e-97 L Integrase
PIKHPIBO_01979 1.8e-34 yoeD G Helix-turn-helix domain
PIKHPIBO_01980 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PIKHPIBO_01981 6.1e-200 ybcL EGP Major facilitator Superfamily
PIKHPIBO_01982 6.7e-50 ybzH K Helix-turn-helix domain
PIKHPIBO_01983 1.3e-271 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PIKHPIBO_01984 1.5e-155 gltR1 K Transcriptional regulator
PIKHPIBO_01985 8.4e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PIKHPIBO_01986 5.8e-52 1.16.3.1 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
PIKHPIBO_01987 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PIKHPIBO_01988 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
PIKHPIBO_01989 2.2e-149 gltC K Transcriptional regulator
PIKHPIBO_01990 8.1e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PIKHPIBO_01991 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIKHPIBO_01992 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PIKHPIBO_01993 4.4e-124 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PIKHPIBO_01994 2.8e-40 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PIKHPIBO_01995 1.4e-136 yoxB
PIKHPIBO_01996 8.5e-203 yoaB EGP Major facilitator Superfamily
PIKHPIBO_01997 1.8e-273 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
PIKHPIBO_01998 2.1e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIKHPIBO_01999 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PIKHPIBO_02000 6.3e-26 yoaF
PIKHPIBO_02002 4.3e-98 hpr K helix_turn_helix multiple antibiotic resistance protein
PIKHPIBO_02003 1.3e-44
PIKHPIBO_02004 1.8e-86 S SMI1-KNR4 cell-wall
PIKHPIBO_02005 7.5e-311 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PIKHPIBO_02006 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
PIKHPIBO_02007 1.9e-132 yobQ K helix_turn_helix, arabinose operon control protein
PIKHPIBO_02008 1.2e-92 yobS K Transcriptional regulator
PIKHPIBO_02009 4.5e-137 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
PIKHPIBO_02010 1.9e-92 yobW
PIKHPIBO_02011 1.7e-54 czrA K transcriptional
PIKHPIBO_02012 3.9e-119 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PIKHPIBO_02013 6.9e-90 yozB S membrane
PIKHPIBO_02014 2.3e-139 yocB J Protein required for attachment to host cells
PIKHPIBO_02015 3.6e-93 yocC
PIKHPIBO_02016 6.7e-184 yocD 3.4.17.13 V peptidase S66
PIKHPIBO_02018 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
PIKHPIBO_02019 0.0 recQ 3.6.4.12 L DNA helicase
PIKHPIBO_02020 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PIKHPIBO_02022 2.3e-60 dksA T general stress protein
PIKHPIBO_02023 1e-09 yocL
PIKHPIBO_02024 2.9e-08
PIKHPIBO_02025 5.8e-88 yocM O Belongs to the small heat shock protein (HSP20) family
PIKHPIBO_02026 1.4e-43 yozN
PIKHPIBO_02027 8.5e-37 yocN
PIKHPIBO_02028 2.4e-56 yozO S Bacterial PH domain
PIKHPIBO_02030 6.1e-31 yozC
PIKHPIBO_02031 2.9e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
PIKHPIBO_02032 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
PIKHPIBO_02033 3.2e-166 sodA 1.15.1.1 P Superoxide dismutase
PIKHPIBO_02034 5.1e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PIKHPIBO_02035 4.6e-161 yocS S -transporter
PIKHPIBO_02036 5e-139 S Metallo-beta-lactamase superfamily
PIKHPIBO_02037 7.2e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PIKHPIBO_02038 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PIKHPIBO_02039 0.0 yojO P Von Willebrand factor
PIKHPIBO_02040 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
PIKHPIBO_02041 1.2e-95 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PIKHPIBO_02042 6.8e-226 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PIKHPIBO_02043 1.9e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
PIKHPIBO_02044 4.8e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PIKHPIBO_02046 1.3e-241 norM V Multidrug efflux pump
PIKHPIBO_02047 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PIKHPIBO_02048 2.5e-126 yojG S deacetylase
PIKHPIBO_02049 9.7e-61 yojF S Protein of unknown function (DUF1806)
PIKHPIBO_02050 4.9e-23
PIKHPIBO_02051 9.2e-164 rarD S -transporter
PIKHPIBO_02052 3.3e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
PIKHPIBO_02054 1.6e-67 yodA S tautomerase
PIKHPIBO_02055 1.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
PIKHPIBO_02056 3e-56 yodB K transcriptional
PIKHPIBO_02057 4.5e-106 yodC C nitroreductase
PIKHPIBO_02058 3.9e-110 mhqD S Carboxylesterase
PIKHPIBO_02059 6.5e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
PIKHPIBO_02060 1.4e-19 S Protein of unknown function (DUF3311)
PIKHPIBO_02061 1e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PIKHPIBO_02062 4.1e-278 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
PIKHPIBO_02063 7.8e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PIKHPIBO_02064 3.4e-132 yydK K Transcriptional regulator
PIKHPIBO_02065 1.4e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
PIKHPIBO_02066 6.3e-128 yodH Q Methyltransferase
PIKHPIBO_02067 4.3e-34 yodI
PIKHPIBO_02068 1.1e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PIKHPIBO_02069 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
PIKHPIBO_02071 3.3e-55 yodL S YodL-like
PIKHPIBO_02072 2.3e-102 yodM 3.6.1.27 I Acid phosphatase homologues
PIKHPIBO_02073 6.2e-24 yozD S YozD-like protein
PIKHPIBO_02075 4.9e-125 yodN
PIKHPIBO_02076 9.1e-36 yozE S Belongs to the UPF0346 family
PIKHPIBO_02077 8.3e-47 yokU S YokU-like protein, putative antitoxin
PIKHPIBO_02078 2.6e-277 kamA 5.4.3.2 E lysine 2,3-aminomutase
PIKHPIBO_02079 3.6e-157 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
PIKHPIBO_02080 6.7e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
PIKHPIBO_02081 1.8e-122 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PIKHPIBO_02082 2.2e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PIKHPIBO_02083 1.2e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PIKHPIBO_02084 4.1e-64 yosT L Bacterial transcription activator, effector binding domain
PIKHPIBO_02086 1.4e-144 yiiD K acetyltransferase
PIKHPIBO_02087 4.5e-249 cgeD M maturation of the outermost layer of the spore
PIKHPIBO_02088 1.1e-41 cgeC
PIKHPIBO_02089 1.6e-52 cgeA
PIKHPIBO_02090 2.8e-179 cgeB S Spore maturation protein
PIKHPIBO_02091 9.8e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
PIKHPIBO_02092 5.3e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
PIKHPIBO_02093 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PIKHPIBO_02094 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PIKHPIBO_02095 4e-66 ypoP K transcriptional
PIKHPIBO_02096 1.6e-97 ypmS S protein conserved in bacteria
PIKHPIBO_02097 1.2e-135 ypmR E GDSL-like Lipase/Acylhydrolase
PIKHPIBO_02098 2.1e-114 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PIKHPIBO_02099 2.6e-39 ypmP S Protein of unknown function (DUF2535)
PIKHPIBO_02100 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PIKHPIBO_02101 4.2e-178 pspF K Transcriptional regulator
PIKHPIBO_02102 9.3e-110 hlyIII S protein, Hemolysin III
PIKHPIBO_02103 6.7e-113 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PIKHPIBO_02104 4.8e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PIKHPIBO_02105 1.9e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PIKHPIBO_02106 2.7e-114 ypjP S YpjP-like protein
PIKHPIBO_02107 7.4e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
PIKHPIBO_02108 1e-75 yphP S Belongs to the UPF0403 family
PIKHPIBO_02109 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PIKHPIBO_02110 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
PIKHPIBO_02111 2.7e-98 ypgQ S phosphohydrolase
PIKHPIBO_02112 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PIKHPIBO_02113 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PIKHPIBO_02114 8.5e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
PIKHPIBO_02115 1e-30 cspD K Cold-shock protein
PIKHPIBO_02116 3.3e-12 degR
PIKHPIBO_02117 6.1e-36 S Protein of unknown function (DUF2564)
PIKHPIBO_02118 1.5e-28 ypeQ S Zinc-finger
PIKHPIBO_02119 2.4e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
PIKHPIBO_02120 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PIKHPIBO_02121 5.4e-68 rnhA 3.1.26.4 L Ribonuclease
PIKHPIBO_02123 1.4e-164 polA 2.7.7.7 L 5'3' exonuclease
PIKHPIBO_02125 3.5e-39 ypbS S Protein of unknown function (DUF2533)
PIKHPIBO_02126 0.0 ypbR S Dynamin family
PIKHPIBO_02127 1.1e-89 ypbQ S protein conserved in bacteria
PIKHPIBO_02128 5.3e-206 bcsA Q Naringenin-chalcone synthase
PIKHPIBO_02129 1e-105 J Acetyltransferase (GNAT) domain
PIKHPIBO_02130 3.4e-49 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
PIKHPIBO_02132 1.5e-98 yrdC 3.5.1.19 Q Isochorismatase family
PIKHPIBO_02133 1.8e-232 pbuX F xanthine
PIKHPIBO_02134 1.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PIKHPIBO_02135 7.1e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PIKHPIBO_02136 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
PIKHPIBO_02138 6.6e-22 S YpzG-like protein
PIKHPIBO_02139 1.6e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PIKHPIBO_02140 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PIKHPIBO_02141 4.8e-99 ypsA S Belongs to the UPF0398 family
PIKHPIBO_02142 9.9e-33 cotD S Inner spore coat protein D
PIKHPIBO_02144 1.9e-236 yprB L RNase_H superfamily
PIKHPIBO_02145 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PIKHPIBO_02146 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
PIKHPIBO_02147 3.8e-72 hspX O Belongs to the small heat shock protein (HSP20) family
PIKHPIBO_02148 6.9e-46 yppG S YppG-like protein
PIKHPIBO_02150 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
PIKHPIBO_02153 7.5e-188 yppC S Protein of unknown function (DUF2515)
PIKHPIBO_02154 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PIKHPIBO_02155 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PIKHPIBO_02156 5.7e-91 ypoC
PIKHPIBO_02157 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PIKHPIBO_02158 4.4e-129 dnaD L DNA replication protein DnaD
PIKHPIBO_02159 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
PIKHPIBO_02160 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PIKHPIBO_02161 4e-81 ypmB S protein conserved in bacteria
PIKHPIBO_02162 6.7e-23 ypmA S Protein of unknown function (DUF4264)
PIKHPIBO_02163 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PIKHPIBO_02164 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PIKHPIBO_02165 1.9e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PIKHPIBO_02166 1.8e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PIKHPIBO_02167 2.4e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PIKHPIBO_02168 1.3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PIKHPIBO_02169 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
PIKHPIBO_02170 1.9e-132 bshB1 S proteins, LmbE homologs
PIKHPIBO_02171 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
PIKHPIBO_02172 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PIKHPIBO_02173 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
PIKHPIBO_02174 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
PIKHPIBO_02175 5.3e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
PIKHPIBO_02176 5.1e-142 ypjB S sporulation protein
PIKHPIBO_02177 1.2e-103 ypjA S membrane
PIKHPIBO_02178 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
PIKHPIBO_02179 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
PIKHPIBO_02180 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
PIKHPIBO_02181 2.5e-77 ypiF S Protein of unknown function (DUF2487)
PIKHPIBO_02182 2.1e-99 ypiB S Belongs to the UPF0302 family
PIKHPIBO_02183 1.2e-233 S COG0457 FOG TPR repeat
PIKHPIBO_02184 4.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PIKHPIBO_02185 2.3e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PIKHPIBO_02186 6.6e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PIKHPIBO_02187 3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PIKHPIBO_02188 4.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PIKHPIBO_02189 4.7e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
PIKHPIBO_02190 3.9e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PIKHPIBO_02191 3.8e-158 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PIKHPIBO_02192 2.4e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PIKHPIBO_02193 9e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PIKHPIBO_02194 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PIKHPIBO_02195 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PIKHPIBO_02196 7.2e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
PIKHPIBO_02197 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PIKHPIBO_02198 2.1e-196 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PIKHPIBO_02199 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PIKHPIBO_02200 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PIKHPIBO_02201 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PIKHPIBO_02202 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
PIKHPIBO_02203 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PIKHPIBO_02204 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PIKHPIBO_02205 1.1e-133 yphF
PIKHPIBO_02206 3.3e-16 yphE S Protein of unknown function (DUF2768)
PIKHPIBO_02207 1.1e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PIKHPIBO_02208 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PIKHPIBO_02209 1.1e-104 yphA
PIKHPIBO_02210 4.7e-08 S YpzI-like protein
PIKHPIBO_02211 3.4e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PIKHPIBO_02212 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
PIKHPIBO_02213 2.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PIKHPIBO_02214 1.4e-12 S Family of unknown function (DUF5359)
PIKHPIBO_02215 1.1e-62 ypfA M Flagellar protein YcgR
PIKHPIBO_02216 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
PIKHPIBO_02217 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
PIKHPIBO_02218 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
PIKHPIBO_02219 2.2e-187 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
PIKHPIBO_02220 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
PIKHPIBO_02221 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PIKHPIBO_02222 2.1e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
PIKHPIBO_02223 5.7e-85 ypbF S Protein of unknown function (DUF2663)
PIKHPIBO_02224 8.9e-75 ypbE M Lysin motif
PIKHPIBO_02225 9.9e-100 ypbD S metal-dependent membrane protease
PIKHPIBO_02226 9.4e-272 recQ 3.6.4.12 L DNA helicase
PIKHPIBO_02227 9.1e-195 ypbB 5.1.3.1 S protein conserved in bacteria
PIKHPIBO_02228 3.6e-41 fer C Ferredoxin
PIKHPIBO_02229 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PIKHPIBO_02230 2.2e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIKHPIBO_02231 1.3e-199 rsiX
PIKHPIBO_02232 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
PIKHPIBO_02233 0.0 resE 2.7.13.3 T Histidine kinase
PIKHPIBO_02234 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_02235 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PIKHPIBO_02236 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
PIKHPIBO_02237 1.6e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PIKHPIBO_02238 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PIKHPIBO_02239 2.9e-88 spmB S Spore maturation protein
PIKHPIBO_02240 4.6e-103 spmA S Spore maturation protein
PIKHPIBO_02241 2.5e-214 dacB 3.4.16.4 M Belongs to the peptidase S11 family
PIKHPIBO_02242 6e-85 ypuI S Protein of unknown function (DUF3907)
PIKHPIBO_02243 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PIKHPIBO_02244 4.7e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PIKHPIBO_02246 8.4e-93 ypuF S Domain of unknown function (DUF309)
PIKHPIBO_02247 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIKHPIBO_02248 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PIKHPIBO_02249 1.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PIKHPIBO_02250 1e-111 ribE 2.5.1.9 H Riboflavin synthase
PIKHPIBO_02251 6.2e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PIKHPIBO_02252 6.4e-49 ypuD
PIKHPIBO_02253 1.3e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PIKHPIBO_02254 2.4e-81 ccdC1 O Protein of unknown function (DUF1453)
PIKHPIBO_02255 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PIKHPIBO_02256 1.9e-153 ypuA S Secreted protein
PIKHPIBO_02257 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PIKHPIBO_02258 1.2e-269 spoVAF EG Stage V sporulation protein AF
PIKHPIBO_02259 1.8e-110 spoVAEA S stage V sporulation protein
PIKHPIBO_02260 3.8e-57 spoVAEB S stage V sporulation protein
PIKHPIBO_02261 5e-190 spoVAD I Stage V sporulation protein AD
PIKHPIBO_02262 1.3e-78 spoVAC S stage V sporulation protein AC
PIKHPIBO_02263 3.9e-60 spoVAB S Stage V sporulation protein AB
PIKHPIBO_02264 3.7e-111 spoVAA S Stage V sporulation protein AA
PIKHPIBO_02265 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIKHPIBO_02266 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PIKHPIBO_02267 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
PIKHPIBO_02268 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
PIKHPIBO_02269 7.1e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PIKHPIBO_02270 5.2e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PIKHPIBO_02271 1.7e-165 xerD L recombinase XerD
PIKHPIBO_02272 3.7e-37 S Protein of unknown function (DUF4227)
PIKHPIBO_02273 1.9e-80 fur P Belongs to the Fur family
PIKHPIBO_02274 1.6e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PIKHPIBO_02275 1.7e-34 yqkK
PIKHPIBO_02276 5.7e-22
PIKHPIBO_02277 7.7e-244 mleA 1.1.1.38 C malic enzyme
PIKHPIBO_02278 2.7e-239 mleN C Na H antiporter
PIKHPIBO_02279 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
PIKHPIBO_02280 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
PIKHPIBO_02281 1.9e-56 ansR K Transcriptional regulator
PIKHPIBO_02282 4e-220 yqxK 3.6.4.12 L DNA helicase
PIKHPIBO_02283 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
PIKHPIBO_02285 4.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
PIKHPIBO_02287 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
PIKHPIBO_02288 3.2e-39 yqkC S Protein of unknown function (DUF2552)
PIKHPIBO_02289 7.7e-61 yqkB S Belongs to the HesB IscA family
PIKHPIBO_02290 1.8e-173 yqkA K GrpB protein
PIKHPIBO_02291 4.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
PIKHPIBO_02292 3.9e-89 yqjY K acetyltransferase
PIKHPIBO_02293 9.4e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIKHPIBO_02294 3.4e-58 S YolD-like protein
PIKHPIBO_02296 2.5e-184 yueF S transporter activity
PIKHPIBO_02298 8e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIKHPIBO_02299 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
PIKHPIBO_02300 4.8e-257 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
PIKHPIBO_02301 5.5e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
PIKHPIBO_02302 3.3e-175 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
PIKHPIBO_02303 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIKHPIBO_02304 9.7e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
PIKHPIBO_02305 2.9e-240 pksG 2.3.3.10 I synthase
PIKHPIBO_02306 2.6e-219 eryK 1.14.13.154 C Cytochrome P450
PIKHPIBO_02307 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PIKHPIBO_02308 0.0 Q Polyketide synthase of type I
PIKHPIBO_02309 0.0 pfaA Q Polyketide synthase of type I
PIKHPIBO_02310 0.0 pksJ Q Polyketide synthase of type I
PIKHPIBO_02311 0.0 Q Polyketide synthase of type I
PIKHPIBO_02312 0.0 1.1.1.320 Q Polyketide synthase of type I
PIKHPIBO_02313 0.0 pksJ Q Polyketide synthase of type I
PIKHPIBO_02314 1.8e-128 IQ reductase
PIKHPIBO_02315 5.9e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PIKHPIBO_02318 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PIKHPIBO_02319 1e-93 nusG K Participates in transcription elongation, termination and antitermination
PIKHPIBO_02320 2.4e-164 K LysR substrate binding domain
PIKHPIBO_02321 1.4e-50 S GlpM protein
PIKHPIBO_02322 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PIKHPIBO_02323 1.1e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PIKHPIBO_02324 1.2e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PIKHPIBO_02325 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PIKHPIBO_02326 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PIKHPIBO_02327 1.9e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIKHPIBO_02328 3.1e-25 yqzJ
PIKHPIBO_02329 1.3e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIKHPIBO_02330 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
PIKHPIBO_02331 2.8e-290 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PIKHPIBO_02332 4.2e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
PIKHPIBO_02334 3.1e-95 yqjB S protein conserved in bacteria
PIKHPIBO_02335 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
PIKHPIBO_02336 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PIKHPIBO_02337 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
PIKHPIBO_02338 1.2e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
PIKHPIBO_02339 1.7e-75 yqiW S Belongs to the UPF0403 family
PIKHPIBO_02340 7.7e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PIKHPIBO_02341 1.1e-202 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PIKHPIBO_02342 2.3e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PIKHPIBO_02343 8.6e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PIKHPIBO_02344 1.8e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PIKHPIBO_02345 2e-208 buk 2.7.2.7 C Belongs to the acetokinase family
PIKHPIBO_02346 2e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
PIKHPIBO_02347 4.3e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
PIKHPIBO_02348 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
PIKHPIBO_02349 7e-34 yqzF S Protein of unknown function (DUF2627)
PIKHPIBO_02350 8.1e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PIKHPIBO_02351 7e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
PIKHPIBO_02352 1.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
PIKHPIBO_02353 4.2e-206 mmgC I acyl-CoA dehydrogenase
PIKHPIBO_02354 1.8e-148 hbdA 1.1.1.157 I Dehydrogenase
PIKHPIBO_02355 7.5e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
PIKHPIBO_02356 1.1e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PIKHPIBO_02357 1.4e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
PIKHPIBO_02358 2.5e-17
PIKHPIBO_02359 1.5e-101 ytaF P Probably functions as a manganese efflux pump
PIKHPIBO_02360 1.2e-112 K Protein of unknown function (DUF1232)
PIKHPIBO_02362 3.2e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PIKHPIBO_02365 5.2e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PIKHPIBO_02366 5.5e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PIKHPIBO_02367 4.7e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
PIKHPIBO_02368 1.2e-305 recN L May be involved in recombinational repair of damaged DNA
PIKHPIBO_02369 3.9e-78 argR K Regulates arginine biosynthesis genes
PIKHPIBO_02370 9.6e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
PIKHPIBO_02371 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PIKHPIBO_02372 6.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PIKHPIBO_02373 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIKHPIBO_02374 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIKHPIBO_02375 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PIKHPIBO_02376 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PIKHPIBO_02377 8.1e-67 yqhY S protein conserved in bacteria
PIKHPIBO_02378 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PIKHPIBO_02379 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PIKHPIBO_02380 2.5e-62 spoIIIAH S SpoIIIAH-like protein
PIKHPIBO_02381 1e-117 spoIIIAG S stage III sporulation protein AG
PIKHPIBO_02382 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
PIKHPIBO_02383 6.3e-200 spoIIIAE S stage III sporulation protein AE
PIKHPIBO_02384 3.3e-41 spoIIIAD S Stage III sporulation protein AD
PIKHPIBO_02385 7.6e-29 spoIIIAC S stage III sporulation protein AC
PIKHPIBO_02386 1.7e-85 spoIIIAB S Stage III sporulation protein
PIKHPIBO_02387 1.1e-172 spoIIIAA S stage III sporulation protein AA
PIKHPIBO_02388 1.8e-36 yqhV S Protein of unknown function (DUF2619)
PIKHPIBO_02389 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIKHPIBO_02390 2.1e-175 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
PIKHPIBO_02391 4.9e-88 yqhR S Conserved membrane protein YqhR
PIKHPIBO_02392 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
PIKHPIBO_02393 3.4e-62 yqhP
PIKHPIBO_02394 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
PIKHPIBO_02395 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PIKHPIBO_02396 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PIKHPIBO_02397 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
PIKHPIBO_02398 4.1e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PIKHPIBO_02399 8.7e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PIKHPIBO_02400 3.1e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
PIKHPIBO_02401 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PIKHPIBO_02402 8.4e-153 yqhG S Bacterial protein YqhG of unknown function
PIKHPIBO_02403 1.3e-21 sinI S Anti-repressor SinI
PIKHPIBO_02404 7.8e-55 sinR K transcriptional
PIKHPIBO_02405 3.3e-141 tasA S Cell division protein FtsN
PIKHPIBO_02406 3.5e-71 sipW 3.4.21.89 U Signal peptidase
PIKHPIBO_02407 7.2e-121 yqxM
PIKHPIBO_02408 1.3e-54 yqzG S Protein of unknown function (DUF3889)
PIKHPIBO_02409 2.3e-26 yqzE S YqzE-like protein
PIKHPIBO_02410 8e-61 S ComG operon protein 7
PIKHPIBO_02411 7.5e-77 comGF U Putative Competence protein ComGF
PIKHPIBO_02412 2e-20 comGE
PIKHPIBO_02413 6.9e-72 gspH NU Tfp pilus assembly protein FimT
PIKHPIBO_02414 7.5e-49 comGC U Required for transformation and DNA binding
PIKHPIBO_02415 4.6e-183 comGB NU COG1459 Type II secretory pathway, component PulF
PIKHPIBO_02416 8.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PIKHPIBO_02417 1.5e-185 corA P Mg2 transporter protein
PIKHPIBO_02418 6.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PIKHPIBO_02419 1e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PIKHPIBO_02421 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
PIKHPIBO_02422 3.1e-37 yqgY S Protein of unknown function (DUF2626)
PIKHPIBO_02423 3.6e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PIKHPIBO_02424 5.4e-20 yqgW S Protein of unknown function (DUF2759)
PIKHPIBO_02425 1.2e-49 yqgV S Thiamine-binding protein
PIKHPIBO_02426 3e-198 yqgU
PIKHPIBO_02427 2.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
PIKHPIBO_02428 4.9e-179 glcK 2.7.1.2 G Glucokinase
PIKHPIBO_02429 1e-28 yqgQ S Protein conserved in bacteria
PIKHPIBO_02430 1.6e-231 nhaC C Na H antiporter
PIKHPIBO_02432 4.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PIKHPIBO_02433 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PIKHPIBO_02434 1.2e-50 yqzD
PIKHPIBO_02435 1.6e-74 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PIKHPIBO_02436 2.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIKHPIBO_02437 2.3e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIKHPIBO_02438 1.8e-156 pstA P Phosphate transport system permease
PIKHPIBO_02439 5.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
PIKHPIBO_02440 1.7e-157 pstS P Phosphate
PIKHPIBO_02441 0.0 pbpA 3.4.16.4 M penicillin-binding protein
PIKHPIBO_02442 2e-228 yqgE EGP Major facilitator superfamily
PIKHPIBO_02443 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
PIKHPIBO_02444 6e-77 yqgC S protein conserved in bacteria
PIKHPIBO_02445 8.7e-131 yqgB S Protein of unknown function (DUF1189)
PIKHPIBO_02446 3.1e-47 yqfZ M LysM domain
PIKHPIBO_02447 4.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PIKHPIBO_02448 2.3e-52 yqfX S membrane
PIKHPIBO_02449 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
PIKHPIBO_02450 2.9e-72 zur P Belongs to the Fur family
PIKHPIBO_02451 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
PIKHPIBO_02452 1.6e-36 yqfT S Protein of unknown function (DUF2624)
PIKHPIBO_02453 3.7e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PIKHPIBO_02454 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PIKHPIBO_02455 6.2e-51 yqfQ S YqfQ-like protein
PIKHPIBO_02456 7.1e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PIKHPIBO_02457 2.5e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PIKHPIBO_02458 1.3e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
PIKHPIBO_02459 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
PIKHPIBO_02460 9e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PIKHPIBO_02461 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PIKHPIBO_02462 6.1e-88 yaiI S Belongs to the UPF0178 family
PIKHPIBO_02463 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PIKHPIBO_02464 4.5e-112 ccpN K CBS domain
PIKHPIBO_02465 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PIKHPIBO_02466 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PIKHPIBO_02467 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
PIKHPIBO_02468 1.8e-16 S YqzL-like protein
PIKHPIBO_02469 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PIKHPIBO_02470 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PIKHPIBO_02471 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PIKHPIBO_02472 5.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PIKHPIBO_02473 0.0 yqfF S membrane-associated HD superfamily hydrolase
PIKHPIBO_02474 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
PIKHPIBO_02475 4.2e-217 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
PIKHPIBO_02476 9.3e-46 yqfC S sporulation protein YqfC
PIKHPIBO_02477 3.4e-55 yqfB
PIKHPIBO_02478 1.6e-121 yqfA S UPF0365 protein
PIKHPIBO_02479 5.7e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
PIKHPIBO_02480 1.2e-68 yqeY S Yqey-like protein
PIKHPIBO_02481 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PIKHPIBO_02482 1e-157 yqeW P COG1283 Na phosphate symporter
PIKHPIBO_02483 1.2e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
PIKHPIBO_02484 3.9e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PIKHPIBO_02485 1.6e-174 prmA J Methylates ribosomal protein L11
PIKHPIBO_02486 1.9e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PIKHPIBO_02487 0.0 dnaK O Heat shock 70 kDa protein
PIKHPIBO_02488 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PIKHPIBO_02489 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PIKHPIBO_02490 1.8e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
PIKHPIBO_02491 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PIKHPIBO_02492 3.8e-54 yqxA S Protein of unknown function (DUF3679)
PIKHPIBO_02493 1.4e-220 spoIIP M stage II sporulation protein P
PIKHPIBO_02494 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PIKHPIBO_02495 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
PIKHPIBO_02496 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
PIKHPIBO_02497 0.0 comEC S Competence protein ComEC
PIKHPIBO_02498 8e-105 comEB 3.5.4.12 F ComE operon protein 2
PIKHPIBO_02499 2.8e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PIKHPIBO_02500 8.7e-145 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIKHPIBO_02501 2.2e-139 yqeM Q Methyltransferase
PIKHPIBO_02502 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PIKHPIBO_02503 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PIKHPIBO_02504 5e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PIKHPIBO_02505 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
PIKHPIBO_02506 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PIKHPIBO_02507 5.9e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PIKHPIBO_02508 2e-94 yqeG S hydrolase of the HAD superfamily
PIKHPIBO_02510 1.9e-138 yqeF E GDSL-like Lipase/Acylhydrolase
PIKHPIBO_02511 2e-140 3.5.1.104 G Polysaccharide deacetylase
PIKHPIBO_02512 1.8e-105 yqeD S SNARE associated Golgi protein
PIKHPIBO_02513 6.9e-218 EGP Major facilitator Superfamily
PIKHPIBO_02514 9.8e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PIKHPIBO_02515 1.3e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
PIKHPIBO_02516 3.3e-77 K Transcriptional regulator PadR-like family
PIKHPIBO_02517 2.8e-149 ydeE K AraC family transcriptional regulator
PIKHPIBO_02518 1.8e-106 K Transcriptional regulator
PIKHPIBO_02519 7e-125 yecA E amino acid
PIKHPIBO_02520 7.7e-32 yyaR K acetyltransferase
PIKHPIBO_02521 2.1e-220 tetL EGP Major facilitator Superfamily
PIKHPIBO_02522 5.7e-81 yyaR K Acetyltransferase (GNAT) domain
PIKHPIBO_02523 1.1e-92 yrdA S DinB family
PIKHPIBO_02525 7.7e-146 S hydrolase
PIKHPIBO_02526 1.4e-98 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
PIKHPIBO_02527 1.3e-33 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
PIKHPIBO_02528 1.2e-129 glvR K Helix-turn-helix domain, rpiR family
PIKHPIBO_02529 1.2e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
PIKHPIBO_02530 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
PIKHPIBO_02531 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
PIKHPIBO_02532 2.2e-181 romA S Beta-lactamase superfamily domain
PIKHPIBO_02533 4e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PIKHPIBO_02534 2.4e-164 yybE K Transcriptional regulator
PIKHPIBO_02535 6.5e-213 ynfM EGP Major facilitator Superfamily
PIKHPIBO_02536 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
PIKHPIBO_02537 3.8e-99 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
PIKHPIBO_02538 3.9e-93 yrhH Q methyltransferase
PIKHPIBO_02540 8e-143 focA P Formate nitrite
PIKHPIBO_02541 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
PIKHPIBO_02542 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
PIKHPIBO_02543 4.5e-80 yrhD S Protein of unknown function (DUF1641)
PIKHPIBO_02544 4.6e-35 yrhC S YrhC-like protein
PIKHPIBO_02545 1.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PIKHPIBO_02546 1.4e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
PIKHPIBO_02547 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PIKHPIBO_02548 1.3e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
PIKHPIBO_02549 4.1e-27 yrzA S Protein of unknown function (DUF2536)
PIKHPIBO_02550 4e-69 yrrS S Protein of unknown function (DUF1510)
PIKHPIBO_02551 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
PIKHPIBO_02552 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIKHPIBO_02553 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
PIKHPIBO_02554 2.7e-246 yegQ O COG0826 Collagenase and related proteases
PIKHPIBO_02555 1.7e-173 yegQ O Peptidase U32
PIKHPIBO_02556 9.5e-118 yrrM 2.1.1.104 S O-methyltransferase
PIKHPIBO_02557 1.4e-185 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PIKHPIBO_02558 7.1e-46 yrzB S Belongs to the UPF0473 family
PIKHPIBO_02559 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PIKHPIBO_02560 8.5e-41 yrzL S Belongs to the UPF0297 family
PIKHPIBO_02561 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PIKHPIBO_02562 2.4e-163 yrrI S AI-2E family transporter
PIKHPIBO_02563 1.2e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PIKHPIBO_02564 7.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
PIKHPIBO_02565 1.2e-109 gluC P ABC transporter
PIKHPIBO_02566 3.7e-99 glnP P ABC transporter
PIKHPIBO_02567 2.1e-08 S Protein of unknown function (DUF3918)
PIKHPIBO_02568 2.9e-30 yrzR
PIKHPIBO_02569 1.8e-83 yrrD S protein conserved in bacteria
PIKHPIBO_02570 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PIKHPIBO_02571 1.7e-18 S COG0457 FOG TPR repeat
PIKHPIBO_02572 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PIKHPIBO_02573 2.3e-212 iscS 2.8.1.7 E Cysteine desulfurase
PIKHPIBO_02574 7.8e-64 cymR K Transcriptional regulator
PIKHPIBO_02575 7e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PIKHPIBO_02576 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PIKHPIBO_02577 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PIKHPIBO_02578 6.3e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
PIKHPIBO_02581 8.5e-274 lytH 3.5.1.28 M COG3103 SH3 domain protein
PIKHPIBO_02582 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PIKHPIBO_02583 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PIKHPIBO_02584 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PIKHPIBO_02585 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PIKHPIBO_02586 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
PIKHPIBO_02587 1.2e-85 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
PIKHPIBO_02588 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PIKHPIBO_02589 3.8e-50 yrzD S Post-transcriptional regulator
PIKHPIBO_02590 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIKHPIBO_02591 3.1e-108 yrbG S membrane
PIKHPIBO_02592 2.4e-60 yrzE S Protein of unknown function (DUF3792)
PIKHPIBO_02593 7.3e-37 yajC U Preprotein translocase subunit YajC
PIKHPIBO_02594 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PIKHPIBO_02595 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PIKHPIBO_02596 1.6e-20 yrzS S Protein of unknown function (DUF2905)
PIKHPIBO_02597 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PIKHPIBO_02598 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PIKHPIBO_02599 3.7e-93 bofC S BofC C-terminal domain
PIKHPIBO_02601 4.7e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PIKHPIBO_02602 7.4e-145 safA M spore coat assembly protein SafA
PIKHPIBO_02603 1.9e-211 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PIKHPIBO_02604 5.3e-153 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
PIKHPIBO_02605 7.6e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
PIKHPIBO_02606 1.7e-223 nifS 2.8.1.7 E Cysteine desulfurase
PIKHPIBO_02607 5.5e-95 niaR S small molecule binding protein (contains 3H domain)
PIKHPIBO_02608 2.6e-160 pheA 4.2.1.51 E Prephenate dehydratase
PIKHPIBO_02609 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
PIKHPIBO_02610 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PIKHPIBO_02611 3.3e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
PIKHPIBO_02612 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PIKHPIBO_02613 3.2e-56 ysxB J ribosomal protein
PIKHPIBO_02614 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
PIKHPIBO_02615 7.8e-160 spoIVFB S Stage IV sporulation protein
PIKHPIBO_02616 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
PIKHPIBO_02617 2.3e-142 minD D Belongs to the ParA family
PIKHPIBO_02618 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PIKHPIBO_02619 1.4e-84 mreD M shape-determining protein
PIKHPIBO_02620 1.2e-157 mreC M Involved in formation and maintenance of cell shape
PIKHPIBO_02621 4e-184 mreB D Rod shape-determining protein MreB
PIKHPIBO_02622 4.1e-127 radC E Belongs to the UPF0758 family
PIKHPIBO_02623 1.2e-100 maf D septum formation protein Maf
PIKHPIBO_02624 9.7e-138 spoIIB S Sporulation related domain
PIKHPIBO_02625 5.6e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PIKHPIBO_02626 9.6e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PIKHPIBO_02627 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PIKHPIBO_02628 2.1e-25
PIKHPIBO_02629 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PIKHPIBO_02630 1.1e-216 spoVID M stage VI sporulation protein D
PIKHPIBO_02631 1.8e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
PIKHPIBO_02632 1.7e-184 hemB 4.2.1.24 H Belongs to the ALAD family
PIKHPIBO_02633 5e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PIKHPIBO_02634 9.3e-175 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PIKHPIBO_02635 3.6e-146 hemX O cytochrome C
PIKHPIBO_02636 4.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PIKHPIBO_02637 3.2e-86 ysxD
PIKHPIBO_02638 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
PIKHPIBO_02639 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PIKHPIBO_02640 6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
PIKHPIBO_02641 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PIKHPIBO_02642 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PIKHPIBO_02643 2.1e-188 ysoA H Tetratricopeptide repeat
PIKHPIBO_02644 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PIKHPIBO_02645 3.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PIKHPIBO_02646 9.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PIKHPIBO_02647 1.8e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PIKHPIBO_02648 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PIKHPIBO_02649 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
PIKHPIBO_02650 0.0 ilvB 2.2.1.6 E Acetolactate synthase
PIKHPIBO_02653 3.7e-24
PIKHPIBO_02654 1e-76 pinR3 L Resolvase, N terminal domain
PIKHPIBO_02655 4e-121 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PIKHPIBO_02656 2.2e-244 hsdM 2.1.1.72 V Type I restriction-modification system
PIKHPIBO_02657 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
PIKHPIBO_02659 2.4e-36 L Phage integrase family
PIKHPIBO_02662 4.2e-89 ysnB S Phosphoesterase
PIKHPIBO_02663 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PIKHPIBO_02664 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PIKHPIBO_02665 8.1e-199 gerM S COG5401 Spore germination protein
PIKHPIBO_02666 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PIKHPIBO_02667 4.8e-73 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
PIKHPIBO_02668 2e-30 gerE K Transcriptional regulator
PIKHPIBO_02669 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
PIKHPIBO_02670 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
PIKHPIBO_02671 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
PIKHPIBO_02672 4.8e-108 sdhC C succinate dehydrogenase
PIKHPIBO_02673 1.2e-79 yslB S Protein of unknown function (DUF2507)
PIKHPIBO_02674 1.2e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
PIKHPIBO_02675 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PIKHPIBO_02676 2.5e-52 trxA O Belongs to the thioredoxin family
PIKHPIBO_02677 5.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
PIKHPIBO_02678 2.7e-177 etfA C Electron transfer flavoprotein
PIKHPIBO_02679 5.7e-138 etfB C Electron transfer flavoprotein
PIKHPIBO_02680 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
PIKHPIBO_02681 9.2e-104 fadR K Transcriptional regulator
PIKHPIBO_02682 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PIKHPIBO_02683 1.3e-125 ywbB S Protein of unknown function (DUF2711)
PIKHPIBO_02684 4.7e-67 yshE S membrane
PIKHPIBO_02685 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PIKHPIBO_02686 0.0 polX L COG1796 DNA polymerase IV (family X)
PIKHPIBO_02687 1.6e-83 cvpA S membrane protein, required for colicin V production
PIKHPIBO_02688 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PIKHPIBO_02689 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIKHPIBO_02690 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIKHPIBO_02691 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PIKHPIBO_02692 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIKHPIBO_02693 2e-32 sspI S Belongs to the SspI family
PIKHPIBO_02694 4.2e-203 ysfB KT regulator
PIKHPIBO_02695 1.8e-259 glcD 1.1.3.15 C FAD binding domain
PIKHPIBO_02696 3.7e-254 glcF C Glycolate oxidase
PIKHPIBO_02697 0.0 cstA T Carbon starvation protein
PIKHPIBO_02698 7.8e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
PIKHPIBO_02699 9.9e-144 araQ G transport system permease
PIKHPIBO_02700 1.1e-167 araP P PFAM binding-protein-dependent transport systems inner membrane component
PIKHPIBO_02701 7.6e-252 araN G carbohydrate transport
PIKHPIBO_02702 1.5e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PIKHPIBO_02703 3.2e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
PIKHPIBO_02704 7.1e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PIKHPIBO_02705 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
PIKHPIBO_02706 5.8e-296 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PIKHPIBO_02707 4.4e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
PIKHPIBO_02708 1.8e-206 ysdC G COG1363 Cellulase M and related proteins
PIKHPIBO_02709 1.7e-66 ysdB S Sigma-w pathway protein YsdB
PIKHPIBO_02710 8.2e-41 ysdA S Membrane
PIKHPIBO_02711 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PIKHPIBO_02712 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PIKHPIBO_02713 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PIKHPIBO_02714 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PIKHPIBO_02715 9.1e-40 lrgA S effector of murein hydrolase LrgA
PIKHPIBO_02716 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
PIKHPIBO_02717 0.0 lytS 2.7.13.3 T Histidine kinase
PIKHPIBO_02718 3.5e-151 ysaA S HAD-hyrolase-like
PIKHPIBO_02719 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PIKHPIBO_02720 6.7e-153 ytxC S YtxC-like family
PIKHPIBO_02721 2.7e-109 ytxB S SNARE associated Golgi protein
PIKHPIBO_02722 4.3e-172 dnaI L Primosomal protein DnaI
PIKHPIBO_02723 2.9e-257 dnaB L Membrane attachment protein
PIKHPIBO_02724 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PIKHPIBO_02725 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PIKHPIBO_02726 8.8e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PIKHPIBO_02727 2e-67 ytcD K Transcriptional regulator
PIKHPIBO_02728 1.7e-205 ytbD EGP Major facilitator Superfamily
PIKHPIBO_02729 2.2e-159 ytbE S reductase
PIKHPIBO_02730 1.3e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PIKHPIBO_02731 9.5e-107 ytaF P Probably functions as a manganese efflux pump
PIKHPIBO_02732 3.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PIKHPIBO_02733 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PIKHPIBO_02734 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
PIKHPIBO_02735 4.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_02736 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
PIKHPIBO_02737 3.1e-242 icd 1.1.1.42 C isocitrate
PIKHPIBO_02738 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
PIKHPIBO_02739 4.9e-106 S aspartate phosphatase
PIKHPIBO_02740 1.9e-36
PIKHPIBO_02741 9.3e-66
PIKHPIBO_02743 2.5e-47 yjdF S Protein of unknown function (DUF2992)
PIKHPIBO_02744 1.1e-72 yeaL S membrane
PIKHPIBO_02745 4.8e-194 ytvI S sporulation integral membrane protein YtvI
PIKHPIBO_02746 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
PIKHPIBO_02747 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PIKHPIBO_02748 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PIKHPIBO_02749 4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PIKHPIBO_02750 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PIKHPIBO_02751 9.8e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
PIKHPIBO_02752 0.0 dnaE 2.7.7.7 L DNA polymerase
PIKHPIBO_02753 3.2e-56 ytrH S Sporulation protein YtrH
PIKHPIBO_02754 5.1e-87 ytrI
PIKHPIBO_02755 5.8e-23
PIKHPIBO_02756 2.7e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
PIKHPIBO_02757 5.3e-47 ytpI S YtpI-like protein
PIKHPIBO_02758 2.8e-238 ytoI K transcriptional regulator containing CBS domains
PIKHPIBO_02759 2.5e-129 ytkL S Belongs to the UPF0173 family
PIKHPIBO_02760 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIKHPIBO_02762 2e-263 argH 4.3.2.1 E argininosuccinate lyase
PIKHPIBO_02763 2.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PIKHPIBO_02764 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PIKHPIBO_02765 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIKHPIBO_02766 4.4e-183 ytxK 2.1.1.72 L DNA methylase
PIKHPIBO_02767 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PIKHPIBO_02768 1.6e-60 ytfJ S Sporulation protein YtfJ
PIKHPIBO_02769 4.2e-108 ytfI S Protein of unknown function (DUF2953)
PIKHPIBO_02770 1.1e-86 yteJ S RDD family
PIKHPIBO_02771 6.4e-182 sppA OU signal peptide peptidase SppA
PIKHPIBO_02772 5.7e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PIKHPIBO_02773 1.1e-310 ytcJ S amidohydrolase
PIKHPIBO_02774 3.2e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PIKHPIBO_02775 3.9e-31 sspB S spore protein
PIKHPIBO_02776 1.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PIKHPIBO_02777 1.4e-209 iscS2 2.8.1.7 E Cysteine desulfurase
PIKHPIBO_02778 4e-240 braB E Component of the transport system for branched-chain amino acids
PIKHPIBO_02779 1.9e-263 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PIKHPIBO_02780 1.7e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
PIKHPIBO_02781 7.7e-109 yttP K Transcriptional regulator
PIKHPIBO_02782 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
PIKHPIBO_02783 4.7e-281 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
PIKHPIBO_02784 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PIKHPIBO_02785 1.1e-256 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
PIKHPIBO_02786 3.4e-100 yokH G SMI1 / KNR4 family
PIKHPIBO_02787 1.8e-13 V HNH endonuclease
PIKHPIBO_02788 1.1e-64 D nuclear chromosome segregation
PIKHPIBO_02791 1.1e-45 S HicB_like antitoxin of bacterial toxin-antitoxin system
PIKHPIBO_02792 1.5e-13 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PIKHPIBO_02794 1.3e-221 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PIKHPIBO_02795 7.3e-09
PIKHPIBO_02796 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
PIKHPIBO_02798 9.5e-138 E GDSL-like Lipase/Acylhydrolase family
PIKHPIBO_02799 1.1e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PIKHPIBO_02800 4.4e-149 K Transcriptional regulator
PIKHPIBO_02801 2e-124 azlC E AzlC protein
PIKHPIBO_02802 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
PIKHPIBO_02803 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PIKHPIBO_02804 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PIKHPIBO_02805 2.6e-120 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PIKHPIBO_02806 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
PIKHPIBO_02807 2.5e-230 acuC BQ histone deacetylase
PIKHPIBO_02808 3.7e-120 motS N Flagellar motor protein
PIKHPIBO_02809 5.1e-145 motA N flagellar motor
PIKHPIBO_02810 6.4e-182 ccpA K catabolite control protein A
PIKHPIBO_02811 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PIKHPIBO_02812 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
PIKHPIBO_02813 1.7e-16 ytxH S COG4980 Gas vesicle protein
PIKHPIBO_02814 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PIKHPIBO_02815 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PIKHPIBO_02816 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
PIKHPIBO_02817 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIKHPIBO_02818 3.7e-148 ytpQ S Belongs to the UPF0354 family
PIKHPIBO_02819 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PIKHPIBO_02820 1.1e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
PIKHPIBO_02821 6.4e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PIKHPIBO_02822 1.7e-51 ytzB S small secreted protein
PIKHPIBO_02823 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
PIKHPIBO_02824 5.1e-164 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
PIKHPIBO_02825 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PIKHPIBO_02826 3.5e-45 ytzH S YtzH-like protein
PIKHPIBO_02827 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
PIKHPIBO_02828 8e-179 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PIKHPIBO_02829 5.2e-170 ytlQ
PIKHPIBO_02830 2.8e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PIKHPIBO_02831 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PIKHPIBO_02832 2.3e-270 pepV 3.5.1.18 E Dipeptidase
PIKHPIBO_02833 5.3e-229 pbuO S permease
PIKHPIBO_02834 2.3e-215 ythQ U Bacterial ABC transporter protein EcsB
PIKHPIBO_02835 1.1e-127 ythP V ABC transporter
PIKHPIBO_02836 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
PIKHPIBO_02837 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PIKHPIBO_02838 7.7e-294 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIKHPIBO_02839 3.3e-236 ytfP S HI0933-like protein
PIKHPIBO_02840 9.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
PIKHPIBO_02841 9e-26 yteV S Sporulation protein Cse60
PIKHPIBO_02842 5.7e-186 msmR K Transcriptional regulator
PIKHPIBO_02843 1e-245 msmE G Bacterial extracellular solute-binding protein
PIKHPIBO_02844 3.7e-168 amyD G Binding-protein-dependent transport system inner membrane component
PIKHPIBO_02845 1.4e-142 amyC P ABC transporter (permease)
PIKHPIBO_02846 4.9e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
PIKHPIBO_02847 1.6e-85 M Acetyltransferase (GNAT) domain
PIKHPIBO_02848 1.3e-51 ytwF P Sulfurtransferase
PIKHPIBO_02849 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PIKHPIBO_02850 1.2e-52 ytvB S Protein of unknown function (DUF4257)
PIKHPIBO_02851 8e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
PIKHPIBO_02852 3e-207 yttB EGP Major facilitator Superfamily
PIKHPIBO_02853 2e-124 ywaF S Integral membrane protein
PIKHPIBO_02854 0.0 bceB V ABC transporter (permease)
PIKHPIBO_02855 9.8e-135 bceA V ABC transporter, ATP-binding protein
PIKHPIBO_02856 3.9e-168 T PhoQ Sensor
PIKHPIBO_02857 9.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_02858 2e-220 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
PIKHPIBO_02859 2.9e-125 ytrE V ABC transporter, ATP-binding protein
PIKHPIBO_02860 3.1e-157
PIKHPIBO_02861 5.4e-165 P ABC-2 family transporter protein
PIKHPIBO_02862 3.8e-163 S ABC-2 family transporter protein
PIKHPIBO_02863 1.9e-161 ytrB P abc transporter atp-binding protein
PIKHPIBO_02864 3.9e-66 ytrA K GntR family transcriptional regulator
PIKHPIBO_02865 1.3e-39 ytzC S Protein of unknown function (DUF2524)
PIKHPIBO_02866 4.7e-190 yhcC S Fe-S oxidoreductase
PIKHPIBO_02867 4.8e-105 ytqB J Putative rRNA methylase
PIKHPIBO_02869 1.8e-142 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
PIKHPIBO_02870 2.4e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
PIKHPIBO_02871 6.6e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
PIKHPIBO_02872 6.7e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PIKHPIBO_02873 9.1e-259 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
PIKHPIBO_02874 0.0 asnB 6.3.5.4 E Asparagine synthase
PIKHPIBO_02875 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PIKHPIBO_02876 6.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PIKHPIBO_02877 1.6e-38 ytmB S Protein of unknown function (DUF2584)
PIKHPIBO_02878 2.8e-145 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PIKHPIBO_02879 2.8e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PIKHPIBO_02880 3.2e-144 ytlC P ABC transporter
PIKHPIBO_02881 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PIKHPIBO_02882 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
PIKHPIBO_02883 1.7e-61 ytkC S Bacteriophage holin family
PIKHPIBO_02884 1.6e-76 dps P Belongs to the Dps family
PIKHPIBO_02886 1.6e-76 ytkA S YtkA-like
PIKHPIBO_02887 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PIKHPIBO_02888 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PIKHPIBO_02889 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
PIKHPIBO_02890 7.9e-41 rpmE2 J Ribosomal protein L31
PIKHPIBO_02891 2.6e-239 cydA 1.10.3.14 C oxidase, subunit
PIKHPIBO_02892 5.8e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
PIKHPIBO_02893 2.3e-24 S Domain of Unknown Function (DUF1540)
PIKHPIBO_02894 1.8e-124 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
PIKHPIBO_02895 2.6e-159 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PIKHPIBO_02896 3.3e-122 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PIKHPIBO_02897 5.8e-122 troA P Belongs to the bacterial solute-binding protein 9 family
PIKHPIBO_02898 3.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PIKHPIBO_02899 5e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PIKHPIBO_02900 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PIKHPIBO_02901 3.2e-155 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PIKHPIBO_02902 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PIKHPIBO_02903 4.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
PIKHPIBO_02904 4.8e-131 dksA T COG1734 DnaK suppressor protein
PIKHPIBO_02905 2.6e-77 tspO T membrane
PIKHPIBO_02914 7.8e-08
PIKHPIBO_02915 1.3e-09
PIKHPIBO_02922 1.6e-08
PIKHPIBO_02927 3.4e-39 S COG NOG14552 non supervised orthologous group
PIKHPIBO_02928 4.8e-97 thiT S Thiamine transporter protein (Thia_YuaJ)
PIKHPIBO_02929 4.7e-176 yuaG 3.4.21.72 S protein conserved in bacteria
PIKHPIBO_02930 5.6e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
PIKHPIBO_02931 2.9e-79 yuaE S DinB superfamily
PIKHPIBO_02932 7.1e-109 yuaD S MOSC domain
PIKHPIBO_02933 1.6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
PIKHPIBO_02934 5.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
PIKHPIBO_02935 1.5e-95 yuaC K Belongs to the GbsR family
PIKHPIBO_02936 1.1e-92 yuaB
PIKHPIBO_02937 5.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
PIKHPIBO_02938 1.8e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIKHPIBO_02939 3.4e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PIKHPIBO_02940 2.8e-122 G Cupin
PIKHPIBO_02941 2.4e-50 yjcN
PIKHPIBO_02943 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PIKHPIBO_02944 1.7e-194 yubA S transporter activity
PIKHPIBO_02945 8.8e-184 ygjR S Oxidoreductase
PIKHPIBO_02946 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
PIKHPIBO_02947 3.1e-236 mcpA NT chemotaxis protein
PIKHPIBO_02948 3.9e-223 mcpA NT chemotaxis protein
PIKHPIBO_02949 8.9e-236 mcpA NT chemotaxis protein
PIKHPIBO_02950 2.8e-221 mcpA NT chemotaxis protein
PIKHPIBO_02951 1.4e-138 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
PIKHPIBO_02952 1.8e-40
PIKHPIBO_02953 1e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PIKHPIBO_02954 1.2e-76 yugU S Uncharacterised protein family UPF0047
PIKHPIBO_02955 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
PIKHPIBO_02956 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
PIKHPIBO_02957 8.3e-117 yugP S Zn-dependent protease
PIKHPIBO_02958 1e-17
PIKHPIBO_02959 1.1e-26 mstX S Membrane-integrating protein Mistic
PIKHPIBO_02960 1.2e-180 yugO P COG1226 Kef-type K transport systems
PIKHPIBO_02961 2.2e-72 yugN S YugN-like family
PIKHPIBO_02963 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
PIKHPIBO_02964 1.2e-95 S NADPH-dependent FMN reductase
PIKHPIBO_02965 1.4e-118 ycaC Q Isochorismatase family
PIKHPIBO_02966 7.4e-230 yugK C Dehydrogenase
PIKHPIBO_02967 8.4e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
PIKHPIBO_02968 1.8e-34 yuzA S Domain of unknown function (DUF378)
PIKHPIBO_02969 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
PIKHPIBO_02970 2.1e-208 yugH 2.6.1.1 E Aminotransferase
PIKHPIBO_02971 2e-83 alaR K Transcriptional regulator
PIKHPIBO_02972 1.1e-155 yugF I Hydrolase
PIKHPIBO_02973 2.7e-39 yugE S Domain of unknown function (DUF1871)
PIKHPIBO_02974 3.5e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PIKHPIBO_02975 8.1e-230 T PhoQ Sensor
PIKHPIBO_02976 2.6e-67 kapB G Kinase associated protein B
PIKHPIBO_02977 4.5e-118 kapD L the KinA pathway to sporulation
PIKHPIBO_02978 2e-185 yuxJ EGP Major facilitator Superfamily
PIKHPIBO_02979 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
PIKHPIBO_02980 4.2e-71 yuxK S protein conserved in bacteria
PIKHPIBO_02981 9.3e-74 yufK S Family of unknown function (DUF5366)
PIKHPIBO_02982 6.4e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PIKHPIBO_02983 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
PIKHPIBO_02984 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
PIKHPIBO_02985 1.6e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PIKHPIBO_02986 1.1e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
PIKHPIBO_02987 1e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
PIKHPIBO_02989 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PIKHPIBO_02990 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PIKHPIBO_02991 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PIKHPIBO_02992 9.9e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PIKHPIBO_02993 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PIKHPIBO_02994 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PIKHPIBO_02995 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
PIKHPIBO_02996 3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
PIKHPIBO_02997 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIKHPIBO_02998 0.0 comP 2.7.13.3 T Histidine kinase
PIKHPIBO_03000 4.6e-94 comQ H Polyprenyl synthetase
PIKHPIBO_03002 4e-51 yuzC
PIKHPIBO_03003 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
PIKHPIBO_03004 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PIKHPIBO_03005 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
PIKHPIBO_03006 2.1e-67 yueI S Protein of unknown function (DUF1694)
PIKHPIBO_03007 2.8e-38 yueH S YueH-like protein
PIKHPIBO_03008 6.4e-34 yueG S Spore germination protein gerPA/gerPF
PIKHPIBO_03009 5.6e-187 yueF S transporter activity
PIKHPIBO_03010 1.6e-22 S Protein of unknown function (DUF2642)
PIKHPIBO_03011 3.7e-96 yueE S phosphohydrolase
PIKHPIBO_03012 3e-128 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIKHPIBO_03013 7.7e-77 yueC S Family of unknown function (DUF5383)
PIKHPIBO_03014 0.0 esaA S type VII secretion protein EsaA
PIKHPIBO_03015 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PIKHPIBO_03016 4.8e-206 essB S WXG100 protein secretion system (Wss), protein YukC
PIKHPIBO_03017 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
PIKHPIBO_03018 3.3e-46 esxA S Belongs to the WXG100 family
PIKHPIBO_03019 3.2e-228 yukF QT Transcriptional regulator
PIKHPIBO_03020 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
PIKHPIBO_03021 7.5e-134 yukJ S Uncharacterized conserved protein (DUF2278)
PIKHPIBO_03022 1.3e-34 mbtH S MbtH-like protein
PIKHPIBO_03023 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_03024 4.2e-172 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
PIKHPIBO_03025 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
PIKHPIBO_03026 2.6e-222 entC 5.4.4.2 HQ Isochorismate synthase
PIKHPIBO_03027 1e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PIKHPIBO_03028 3.6e-165 besA S Putative esterase
PIKHPIBO_03029 4.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
PIKHPIBO_03030 1.1e-101 bioY S Biotin biosynthesis protein
PIKHPIBO_03031 2.4e-208 yuiF S antiporter
PIKHPIBO_03032 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PIKHPIBO_03033 1.2e-77 yuiD S protein conserved in bacteria
PIKHPIBO_03034 6e-117 yuiC S protein conserved in bacteria
PIKHPIBO_03035 9.9e-28 yuiB S Putative membrane protein
PIKHPIBO_03036 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
PIKHPIBO_03037 1.5e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
PIKHPIBO_03039 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIKHPIBO_03040 4.8e-29
PIKHPIBO_03041 2e-70 CP Membrane
PIKHPIBO_03042 8.9e-122 V ABC transporter
PIKHPIBO_03044 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
PIKHPIBO_03046 7.2e-95 rimJ 2.3.1.128 J Alanine acetyltransferase
PIKHPIBO_03047 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
PIKHPIBO_03048 1.1e-62 erpA S Belongs to the HesB IscA family
PIKHPIBO_03049 1.6e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PIKHPIBO_03050 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PIKHPIBO_03051 2.4e-39 yuzB S Belongs to the UPF0349 family
PIKHPIBO_03052 7.2e-208 yutJ 1.6.99.3 C NADH dehydrogenase
PIKHPIBO_03053 6.7e-56 yuzD S protein conserved in bacteria
PIKHPIBO_03054 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
PIKHPIBO_03055 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
PIKHPIBO_03056 7.5e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PIKHPIBO_03057 2.2e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PIKHPIBO_03058 3.5e-241 hom 1.1.1.3 E homoserine dehydrogenase
PIKHPIBO_03059 1.2e-196 yutH S Spore coat protein
PIKHPIBO_03060 7.9e-87 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
PIKHPIBO_03061 1e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PIKHPIBO_03062 1.4e-72 yutE S Protein of unknown function DUF86
PIKHPIBO_03063 1.7e-47 yutD S protein conserved in bacteria
PIKHPIBO_03064 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PIKHPIBO_03065 3.8e-195 lytH M Peptidase, M23
PIKHPIBO_03066 4.8e-129 yunB S Sporulation protein YunB (Spo_YunB)
PIKHPIBO_03067 2.4e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PIKHPIBO_03068 1.8e-145 yunE S membrane transporter protein
PIKHPIBO_03069 3.1e-169 yunF S Protein of unknown function DUF72
PIKHPIBO_03070 1.5e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
PIKHPIBO_03071 7e-264 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
PIKHPIBO_03072 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
PIKHPIBO_03074 2.9e-213 blt EGP Major facilitator Superfamily
PIKHPIBO_03075 2.5e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PIKHPIBO_03076 8.9e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PIKHPIBO_03077 4.1e-169 bsn L Ribonuclease
PIKHPIBO_03078 3.1e-206 msmX P Belongs to the ABC transporter superfamily
PIKHPIBO_03079 1e-133 yurK K UTRA
PIKHPIBO_03080 1e-159 yurL 2.7.1.218 G pfkB family carbohydrate kinase
PIKHPIBO_03081 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
PIKHPIBO_03082 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
PIKHPIBO_03083 3.1e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
PIKHPIBO_03084 2e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PIKHPIBO_03085 2.5e-164 K helix_turn_helix, mercury resistance
PIKHPIBO_03086 8.8e-14
PIKHPIBO_03087 3.4e-76
PIKHPIBO_03088 2.1e-22 S Sporulation delaying protein SdpA
PIKHPIBO_03090 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
PIKHPIBO_03091 7.3e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
PIKHPIBO_03092 7.3e-34
PIKHPIBO_03093 9.4e-25
PIKHPIBO_03094 3.9e-24 yncE S Protein of unknown function (DUF2691)
PIKHPIBO_03095 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
PIKHPIBO_03096 3e-270 sufB O FeS cluster assembly
PIKHPIBO_03097 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
PIKHPIBO_03098 4.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PIKHPIBO_03099 1e-243 sufD O assembly protein SufD
PIKHPIBO_03100 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PIKHPIBO_03101 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PIKHPIBO_03102 1.1e-144 metQ P Belongs to the NlpA lipoprotein family
PIKHPIBO_03103 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
PIKHPIBO_03104 1.8e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PIKHPIBO_03105 5e-57 yusD S SCP-2 sterol transfer family
PIKHPIBO_03106 1.6e-54 yusE CO Thioredoxin
PIKHPIBO_03107 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
PIKHPIBO_03108 3.7e-40 yusG S Protein of unknown function (DUF2553)
PIKHPIBO_03109 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PIKHPIBO_03110 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
PIKHPIBO_03111 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
PIKHPIBO_03112 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
PIKHPIBO_03113 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
PIKHPIBO_03114 1.8e-167 fadM E Proline dehydrogenase
PIKHPIBO_03115 2.6e-42
PIKHPIBO_03116 1.1e-53 yusN M Coat F domain
PIKHPIBO_03117 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
PIKHPIBO_03118 8.1e-288 yusP P Major facilitator superfamily
PIKHPIBO_03119 7.4e-158 ywbI2 K Transcriptional regulator
PIKHPIBO_03120 1.5e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
PIKHPIBO_03121 4.3e-189 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PIKHPIBO_03122 3.3e-39 yusU S Protein of unknown function (DUF2573)
PIKHPIBO_03123 1.4e-150 yusV 3.6.3.34 HP ABC transporter
PIKHPIBO_03124 4.2e-45 S YusW-like protein
PIKHPIBO_03125 0.0 pepF2 E COG1164 Oligoendopeptidase F
PIKHPIBO_03126 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PIKHPIBO_03127 1.6e-79 dps P Belongs to the Dps family
PIKHPIBO_03128 2e-239 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PIKHPIBO_03129 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_03130 3.9e-251 cssS 2.7.13.3 T PhoQ Sensor
PIKHPIBO_03131 3.4e-24
PIKHPIBO_03132 4.3e-158 yuxN K Transcriptional regulator
PIKHPIBO_03133 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PIKHPIBO_03134 6.6e-24 S Protein of unknown function (DUF3970)
PIKHPIBO_03135 3.2e-259 gerAA EG Spore germination protein
PIKHPIBO_03136 8e-186 gerAB E Spore germination protein
PIKHPIBO_03137 2.1e-202 gerAC S Spore germination B3/ GerAC like, C-terminal
PIKHPIBO_03138 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIKHPIBO_03139 2.3e-193 vraS 2.7.13.3 T Histidine kinase
PIKHPIBO_03140 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
PIKHPIBO_03141 6.2e-141 liaG S Putative adhesin
PIKHPIBO_03142 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
PIKHPIBO_03143 3.3e-46 liaI S membrane
PIKHPIBO_03144 2.8e-227 yvqJ EGP Major facilitator Superfamily
PIKHPIBO_03145 8.3e-102 yvqK 2.5.1.17 S Adenosyltransferase
PIKHPIBO_03146 1.3e-224 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
PIKHPIBO_03147 1.1e-179 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIKHPIBO_03148 1.1e-167 yvrC P ABC transporter substrate-binding protein
PIKHPIBO_03149 3.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PIKHPIBO_03150 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
PIKHPIBO_03151 0.0 T PhoQ Sensor
PIKHPIBO_03152 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_03153 1.9e-36
PIKHPIBO_03154 7.1e-101 yvrI K RNA polymerase
PIKHPIBO_03155 1.2e-15 S YvrJ protein family
PIKHPIBO_03156 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
PIKHPIBO_03157 7.1e-66 yvrL S Regulatory protein YrvL
PIKHPIBO_03158 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
PIKHPIBO_03159 4e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIKHPIBO_03160 6.6e-185 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIKHPIBO_03161 8.9e-178 fhuD P ABC transporter
PIKHPIBO_03162 3.6e-123 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PIKHPIBO_03163 1.8e-235 yvsH E Arginine ornithine antiporter
PIKHPIBO_03164 6.1e-14 S Small spore protein J (Spore_SspJ)
PIKHPIBO_03165 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
PIKHPIBO_03166 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PIKHPIBO_03167 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
PIKHPIBO_03168 5.3e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
PIKHPIBO_03169 3.9e-98 modB P COG4149 ABC-type molybdate transport system, permease component
PIKHPIBO_03170 3.7e-114 yfiK K Regulator
PIKHPIBO_03171 9.6e-179 T Histidine kinase
PIKHPIBO_03172 2.4e-170 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
PIKHPIBO_03173 3.7e-191 yfiM V ABC-2 type transporter
PIKHPIBO_03174 4e-196 yfiN V COG0842 ABC-type multidrug transport system, permease component
PIKHPIBO_03175 5e-156 yvgN S reductase
PIKHPIBO_03176 3.2e-86 yvgO
PIKHPIBO_03177 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
PIKHPIBO_03178 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PIKHPIBO_03179 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PIKHPIBO_03180 0.0 helD 3.6.4.12 L DNA helicase
PIKHPIBO_03181 3.1e-99 yvgT S membrane
PIKHPIBO_03182 4.4e-141 S Metallo-peptidase family M12
PIKHPIBO_03183 7.3e-71 bdbC O Required for disulfide bond formation in some proteins
PIKHPIBO_03184 1.2e-102 bdbD O Thioredoxin
PIKHPIBO_03185 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PIKHPIBO_03186 0.0 copA 3.6.3.54 P P-type ATPase
PIKHPIBO_03187 3.4e-29 copZ P Heavy-metal-associated domain
PIKHPIBO_03188 3.7e-48 csoR S transcriptional
PIKHPIBO_03189 3.4e-194 yvaA 1.1.1.371 S Oxidoreductase
PIKHPIBO_03190 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PIKHPIBO_03191 1.8e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIKHPIBO_03192 1.6e-45 ytnI O COG0695 Glutaredoxin and related proteins
PIKHPIBO_03193 4.6e-180 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIKHPIBO_03194 6.2e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PIKHPIBO_03195 4.6e-118 tcyM U Binding-protein-dependent transport system inner membrane component
PIKHPIBO_03196 5.9e-121 tcyL P Binding-protein-dependent transport system inner membrane component
PIKHPIBO_03197 4.9e-148 tcyK M Bacterial periplasmic substrate-binding proteins
PIKHPIBO_03198 4.2e-131 ytmJ ET Bacterial periplasmic substrate-binding proteins
PIKHPIBO_03199 6.6e-101 ytmI K Acetyltransferase (GNAT) domain
PIKHPIBO_03200 2.1e-160 ytlI K LysR substrate binding domain
PIKHPIBO_03201 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PIKHPIBO_03202 2.7e-46 yrdF K ribonuclease inhibitor
PIKHPIBO_03204 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PIKHPIBO_03205 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PIKHPIBO_03206 7.4e-143 est 3.1.1.1 S Carboxylesterase
PIKHPIBO_03207 4.8e-24 secG U Preprotein translocase subunit SecG
PIKHPIBO_03208 6e-35 yvzC K Transcriptional
PIKHPIBO_03209 1.8e-69 K transcriptional
PIKHPIBO_03210 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
PIKHPIBO_03211 4.4e-52 yodB K transcriptional
PIKHPIBO_03212 7.7e-258 T His Kinase A (phosphoacceptor) domain
PIKHPIBO_03213 1.4e-121 K Transcriptional regulatory protein, C terminal
PIKHPIBO_03214 5.4e-136 mutG S ABC-2 family transporter protein
PIKHPIBO_03215 7.9e-121 spaE S ABC-2 family transporter protein
PIKHPIBO_03216 4.6e-126 mutF V ABC transporter, ATP-binding protein
PIKHPIBO_03217 8.9e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
PIKHPIBO_03218 5e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PIKHPIBO_03219 7e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
PIKHPIBO_03220 3.7e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PIKHPIBO_03221 7.3e-76 yvbF K Belongs to the GbsR family
PIKHPIBO_03222 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
PIKHPIBO_03223 1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PIKHPIBO_03224 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
PIKHPIBO_03225 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PIKHPIBO_03226 7.1e-98 yvbF K Belongs to the GbsR family
PIKHPIBO_03227 3.4e-104 yvbG U UPF0056 membrane protein
PIKHPIBO_03228 7.6e-121 exoY M Membrane
PIKHPIBO_03229 0.0 tcaA S response to antibiotic
PIKHPIBO_03230 3e-70 yvbK 3.1.3.25 K acetyltransferase
PIKHPIBO_03231 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PIKHPIBO_03232 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
PIKHPIBO_03233 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PIKHPIBO_03234 2.5e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PIKHPIBO_03235 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PIKHPIBO_03236 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PIKHPIBO_03238 2.1e-252 araE EGP Major facilitator Superfamily
PIKHPIBO_03239 1.3e-204 araR K transcriptional
PIKHPIBO_03240 1.1e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIKHPIBO_03241 4.9e-125 yvbU K Transcriptional regulator
PIKHPIBO_03242 8.5e-157 yvbV EG EamA-like transporter family
PIKHPIBO_03243 3.8e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
PIKHPIBO_03245 2.5e-150 ybbH_1 K RpiR family transcriptional regulator
PIKHPIBO_03246 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
PIKHPIBO_03247 3.1e-224 gntP EG COG2610 H gluconate symporter and related permeases
PIKHPIBO_03249 3.9e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PIKHPIBO_03250 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PIKHPIBO_03251 9.3e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PIKHPIBO_03252 9.8e-222 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIKHPIBO_03253 3e-120 yvfI K COG2186 Transcriptional regulators
PIKHPIBO_03254 4.2e-303 yvfH C L-lactate permease
PIKHPIBO_03255 1.1e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PIKHPIBO_03256 2.7e-32 yvfG S YvfG protein
PIKHPIBO_03257 2e-185 yvfF GM Exopolysaccharide biosynthesis protein
PIKHPIBO_03258 1.6e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
PIKHPIBO_03259 3.9e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
PIKHPIBO_03260 6.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PIKHPIBO_03261 1.2e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIKHPIBO_03262 4e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
PIKHPIBO_03263 4.1e-203 epsI GM pyruvyl transferase
PIKHPIBO_03264 1.3e-193 epsH GT2 S Glycosyltransferase like family 2
PIKHPIBO_03265 3.5e-205 epsG S EpsG family
PIKHPIBO_03266 1e-212 epsF GT4 M Glycosyl transferases group 1
PIKHPIBO_03267 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PIKHPIBO_03268 2e-219 epsD GT4 M Glycosyl transferase 4-like
PIKHPIBO_03269 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
PIKHPIBO_03270 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
PIKHPIBO_03271 2.7e-118 ywqC M biosynthesis protein
PIKHPIBO_03272 5.1e-78 slr K transcriptional
PIKHPIBO_03273 1e-281 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
PIKHPIBO_03275 6.3e-96 ywjB H RibD C-terminal domain
PIKHPIBO_03276 1.5e-112 yyaS S Membrane
PIKHPIBO_03277 2.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIKHPIBO_03278 1.6e-93 padC Q Phenolic acid decarboxylase
PIKHPIBO_03279 5.1e-54 MA20_18690 S Protein of unknown function (DUF3237)
PIKHPIBO_03280 1.3e-15 S Protein of unknown function (DUF1433)
PIKHPIBO_03281 7.1e-25 S Protein of unknown function (DUF1433)
PIKHPIBO_03282 1.1e-21 S Protein of unknown function (DUF1433)
PIKHPIBO_03283 4.9e-17 S Protein of unknown function (DUF1433)
PIKHPIBO_03284 2.6e-229 I Pfam Lipase (class 3)
PIKHPIBO_03285 3.1e-34
PIKHPIBO_03287 3.7e-295 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
PIKHPIBO_03288 4.7e-219 rafB P LacY proton/sugar symporter
PIKHPIBO_03289 1.1e-183 scrR K transcriptional
PIKHPIBO_03290 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PIKHPIBO_03291 5.2e-98 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
PIKHPIBO_03292 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
PIKHPIBO_03293 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
PIKHPIBO_03294 1.7e-109 malA S Protein of unknown function (DUF1189)
PIKHPIBO_03295 2.3e-140 malD P transport
PIKHPIBO_03296 7e-221 malC P COG1175 ABC-type sugar transport systems, permease components
PIKHPIBO_03297 2.3e-205 mdxE G COG2182 Maltose-binding periplasmic proteins domains
PIKHPIBO_03298 2.4e-311 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
PIKHPIBO_03299 1.6e-161 yvdE K Transcriptional regulator
PIKHPIBO_03300 3.4e-103 yvdD 3.2.2.10 S Belongs to the LOG family
PIKHPIBO_03301 9.9e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
PIKHPIBO_03302 1.2e-280 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
PIKHPIBO_03303 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
PIKHPIBO_03304 5e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIKHPIBO_03305 1.6e-79 M Ribonuclease
PIKHPIBO_03306 1.4e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
PIKHPIBO_03307 1.2e-36 crh G Phosphocarrier protein Chr
PIKHPIBO_03308 1.2e-169 whiA K May be required for sporulation
PIKHPIBO_03309 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PIKHPIBO_03310 1.1e-166 rapZ S Displays ATPase and GTPase activities
PIKHPIBO_03311 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PIKHPIBO_03312 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PIKHPIBO_03313 5e-124 usp CBM50 M protein conserved in bacteria
PIKHPIBO_03314 1e-273 S COG0457 FOG TPR repeat
PIKHPIBO_03315 1.2e-189 sasA T Histidine kinase
PIKHPIBO_03316 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_03317 0.0 msbA2 3.6.3.44 V ABC transporter
PIKHPIBO_03318 5.3e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
PIKHPIBO_03319 1.8e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PIKHPIBO_03320 2.2e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PIKHPIBO_03321 3.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PIKHPIBO_03322 9.7e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PIKHPIBO_03323 8.5e-235 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PIKHPIBO_03324 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PIKHPIBO_03325 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PIKHPIBO_03326 1.2e-137 yvpB NU protein conserved in bacteria
PIKHPIBO_03327 4.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
PIKHPIBO_03328 8.8e-108 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PIKHPIBO_03329 1.2e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PIKHPIBO_03330 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PIKHPIBO_03331 3e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PIKHPIBO_03332 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PIKHPIBO_03333 1.5e-132 yvoA K transcriptional
PIKHPIBO_03334 6.2e-105 yxaF K Transcriptional regulator
PIKHPIBO_03335 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
PIKHPIBO_03336 1.5e-40 yvlD S Membrane
PIKHPIBO_03337 3.1e-24 pspB KT PspC domain
PIKHPIBO_03338 9.2e-166 yvlB S Putative adhesin
PIKHPIBO_03339 6.1e-49 yvlA
PIKHPIBO_03340 2.2e-32 yvkN
PIKHPIBO_03341 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PIKHPIBO_03342 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PIKHPIBO_03343 7.6e-33 csbA S protein conserved in bacteria
PIKHPIBO_03344 0.0 yvkC 2.7.9.2 GT Phosphotransferase
PIKHPIBO_03345 1.6e-109 yvkB K Transcriptional regulator
PIKHPIBO_03346 9.6e-226 yvkA EGP Major facilitator Superfamily
PIKHPIBO_03347 5.5e-27 bacT Q Thioesterase domain
PIKHPIBO_03349 1e-177 S Psort location CytoplasmicMembrane, score
PIKHPIBO_03350 3.3e-51 E Saccharopine dehydrogenase
PIKHPIBO_03351 1.8e-99 V ABC transporter transmembrane region
PIKHPIBO_03352 0.0 Q TIGRFAM amino acid adenylation domain
PIKHPIBO_03353 0.0 fusAA Q Non-ribosomal peptide synthetase modules and related proteins
PIKHPIBO_03354 3e-20 L Transposase and inactivated derivatives
PIKHPIBO_03355 6.4e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PIKHPIBO_03356 1.5e-55 swrA S Swarming motility protein
PIKHPIBO_03357 5.5e-256 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
PIKHPIBO_03358 3.7e-228 ywoF P Right handed beta helix region
PIKHPIBO_03359 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PIKHPIBO_03360 1e-122 ftsE D cell division ATP-binding protein FtsE
PIKHPIBO_03361 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
PIKHPIBO_03362 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
PIKHPIBO_03363 2.4e-173 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PIKHPIBO_03364 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIKHPIBO_03365 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PIKHPIBO_03366 6.8e-68
PIKHPIBO_03367 5.9e-10 fliT S bacterial-type flagellum organization
PIKHPIBO_03368 3e-66 fliS N flagellar protein FliS
PIKHPIBO_03369 3.6e-245 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PIKHPIBO_03370 2.1e-100 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PIKHPIBO_03371 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PIKHPIBO_03372 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PIKHPIBO_03373 3.4e-79 yviE
PIKHPIBO_03374 6.1e-163 flgL N Belongs to the bacterial flagellin family
PIKHPIBO_03375 2.8e-274 flgK N flagellar hook-associated protein
PIKHPIBO_03376 8.9e-81 flgN NOU FlgN protein
PIKHPIBO_03377 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
PIKHPIBO_03378 9.2e-74 yvyF S flagellar protein
PIKHPIBO_03379 4.5e-77 comFC S Phosphoribosyl transferase domain
PIKHPIBO_03380 2.4e-41 comFB S Late competence development protein ComFB
PIKHPIBO_03381 1.8e-259 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PIKHPIBO_03382 1.4e-158 degV S protein conserved in bacteria
PIKHPIBO_03383 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIKHPIBO_03384 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PIKHPIBO_03385 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
PIKHPIBO_03386 3.9e-170 yvhJ K Transcriptional regulator
PIKHPIBO_03387 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PIKHPIBO_03388 7.5e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
PIKHPIBO_03389 1.5e-143 tuaG GT2 M Glycosyltransferase like family 2
PIKHPIBO_03390 1.2e-115 tuaF M protein involved in exopolysaccharide biosynthesis
PIKHPIBO_03391 5.9e-258 tuaE M Teichuronic acid biosynthesis protein
PIKHPIBO_03392 8.7e-251 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PIKHPIBO_03393 2.9e-221 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
PIKHPIBO_03394 6.1e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PIKHPIBO_03395 1.8e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PIKHPIBO_03396 2.7e-269 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PIKHPIBO_03397 0.0 lytB 3.5.1.28 D Stage II sporulation protein
PIKHPIBO_03398 8.6e-48
PIKHPIBO_03399 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PIKHPIBO_03400 2.9e-207 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PIKHPIBO_03401 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PIKHPIBO_03402 2.4e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PIKHPIBO_03403 1.7e-151 tagG GM Transport permease protein
PIKHPIBO_03404 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PIKHPIBO_03405 1.8e-292 M Glycosyltransferase like family 2
PIKHPIBO_03406 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
PIKHPIBO_03407 7.7e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PIKHPIBO_03408 1.5e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PIKHPIBO_03409 1.4e-231 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIKHPIBO_03410 1.4e-186 pmi 5.3.1.8 G mannose-6-phosphate isomerase
PIKHPIBO_03411 5.7e-264 gerBA EG Spore germination protein
PIKHPIBO_03412 1.5e-195 gerBB E Spore germination protein
PIKHPIBO_03413 2.8e-210 gerAC S Spore germination protein
PIKHPIBO_03414 4.4e-266 GT2,GT4 J Glycosyl transferase family 2
PIKHPIBO_03415 3.7e-249 ywtG EGP Major facilitator Superfamily
PIKHPIBO_03416 7.2e-178 ywtF K Transcriptional regulator
PIKHPIBO_03417 5.5e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
PIKHPIBO_03418 2.9e-35 yttA 2.7.13.3 S Pfam Transposase IS66
PIKHPIBO_03419 1.4e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PIKHPIBO_03420 1.3e-20 ywtC
PIKHPIBO_03421 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
PIKHPIBO_03422 2.3e-70 pgsC S biosynthesis protein
PIKHPIBO_03423 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
PIKHPIBO_03424 1e-183 gerKA EG Spore germination protein
PIKHPIBO_03425 6.7e-193 gerKB E Spore germination protein
PIKHPIBO_03426 1.3e-202 gerKC S Spore germination B3/ GerAC like, C-terminal
PIKHPIBO_03427 1.3e-179 rbsR K transcriptional
PIKHPIBO_03428 1.9e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PIKHPIBO_03429 4.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PIKHPIBO_03430 9.3e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PIKHPIBO_03431 2.9e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
PIKHPIBO_03432 2.2e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
PIKHPIBO_03433 5.2e-90 batE T Sh3 type 3 domain protein
PIKHPIBO_03434 1.8e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
PIKHPIBO_03435 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
PIKHPIBO_03436 8.9e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PIKHPIBO_03437 9e-167 alsR K LysR substrate binding domain
PIKHPIBO_03438 6.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PIKHPIBO_03439 4.4e-126 ywrJ
PIKHPIBO_03440 9.2e-132 cotB
PIKHPIBO_03441 5e-212 cotH M Spore Coat
PIKHPIBO_03442 2.2e-09
PIKHPIBO_03443 4.3e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PIKHPIBO_03444 3.6e-07 S Domain of unknown function (DUF4181)
PIKHPIBO_03445 1.4e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PIKHPIBO_03446 3.2e-83 ywrC K Transcriptional regulator
PIKHPIBO_03447 5.9e-103 ywrB P Chromate transporter
PIKHPIBO_03448 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
PIKHPIBO_03450 1.4e-93 ywqN S NAD(P)H-dependent
PIKHPIBO_03451 1.8e-156 K Transcriptional regulator
PIKHPIBO_03452 2.2e-131 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
PIKHPIBO_03453 1.7e-48
PIKHPIBO_03455 3.6e-50
PIKHPIBO_03456 1.2e-88
PIKHPIBO_03457 2.1e-33 M COG3209 Rhs family protein
PIKHPIBO_03458 6.5e-47 T DNase/tRNase domain of colicin-like bacteriocin
PIKHPIBO_03459 2e-49
PIKHPIBO_03460 1.8e-304 ywqJ S Pre-toxin TG
PIKHPIBO_03461 4.3e-37 ywqI S Family of unknown function (DUF5344)
PIKHPIBO_03462 8.5e-22 S Domain of unknown function (DUF5082)
PIKHPIBO_03464 1.6e-111 ywqG S Domain of unknown function (DUF1963)
PIKHPIBO_03465 3.6e-20 ywqG S Domain of unknown function (DUF1963)
PIKHPIBO_03466 9.8e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PIKHPIBO_03467 4.2e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
PIKHPIBO_03468 1.3e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
PIKHPIBO_03469 5.2e-112 ywqC M biosynthesis protein
PIKHPIBO_03470 1.3e-14
PIKHPIBO_03471 1e-306 ywqB S SWIM zinc finger
PIKHPIBO_03472 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PIKHPIBO_03473 3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
PIKHPIBO_03474 7.5e-138 glcR K DeoR C terminal sensor domain
PIKHPIBO_03475 1.3e-57 ssbB L Single-stranded DNA-binding protein
PIKHPIBO_03476 4e-62 ywpG
PIKHPIBO_03477 1.1e-68 ywpF S YwpF-like protein
PIKHPIBO_03478 4.1e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PIKHPIBO_03479 2.5e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PIKHPIBO_03480 1.5e-197 S aspartate phosphatase
PIKHPIBO_03481 4.1e-142 flhP N flagellar basal body
PIKHPIBO_03482 3.2e-128 flhO N flagellar basal body
PIKHPIBO_03483 2.7e-180 mbl D Rod shape-determining protein
PIKHPIBO_03484 1.8e-44 spoIIID K Stage III sporulation protein D
PIKHPIBO_03485 8.5e-72 ywoH K transcriptional
PIKHPIBO_03486 4.9e-213 ywoG EGP Major facilitator Superfamily
PIKHPIBO_03487 6.5e-276 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
PIKHPIBO_03488 1.6e-244 ywoD EGP Major facilitator superfamily
PIKHPIBO_03489 1.3e-102 phzA Q Isochorismatase family
PIKHPIBO_03490 2.5e-228 amt P Ammonium transporter
PIKHPIBO_03491 5e-57 nrgB K Belongs to the P(II) protein family
PIKHPIBO_03492 3.2e-209 ftsW D Belongs to the SEDS family
PIKHPIBO_03493 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
PIKHPIBO_03494 6.6e-72 ywnJ S VanZ like family
PIKHPIBO_03495 8.4e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
PIKHPIBO_03496 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
PIKHPIBO_03497 1.2e-10 ywnC S Family of unknown function (DUF5362)
PIKHPIBO_03498 6e-68 ywnF S Family of unknown function (DUF5392)
PIKHPIBO_03499 8.4e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIKHPIBO_03500 3.1e-52 ywnC S Family of unknown function (DUF5362)
PIKHPIBO_03501 2.6e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
PIKHPIBO_03502 1.8e-66 ywnA K Transcriptional regulator
PIKHPIBO_03503 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PIKHPIBO_03504 5.5e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PIKHPIBO_03505 5.9e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PIKHPIBO_03507 2.1e-82 ywmF S Peptidase M50
PIKHPIBO_03508 1.5e-94 S response regulator aspartate phosphatase
PIKHPIBO_03509 4.1e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PIKHPIBO_03510 8.4e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PIKHPIBO_03512 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
PIKHPIBO_03513 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
PIKHPIBO_03514 7.3e-189 spoIID D Stage II sporulation protein D
PIKHPIBO_03515 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIKHPIBO_03516 6.3e-134 ywmB S TATA-box binding
PIKHPIBO_03517 1.3e-32 ywzB S membrane
PIKHPIBO_03518 3.5e-90 ywmA
PIKHPIBO_03519 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PIKHPIBO_03520 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PIKHPIBO_03521 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PIKHPIBO_03522 4.1e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PIKHPIBO_03523 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIKHPIBO_03524 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PIKHPIBO_03525 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIKHPIBO_03526 9.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
PIKHPIBO_03527 2.1e-61 atpI S ATP synthase
PIKHPIBO_03528 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PIKHPIBO_03529 7.3e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PIKHPIBO_03530 5.9e-97 ywlG S Belongs to the UPF0340 family
PIKHPIBO_03531 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
PIKHPIBO_03532 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIKHPIBO_03533 2.6e-84 mntP P Probably functions as a manganese efflux pump
PIKHPIBO_03534 7.3e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PIKHPIBO_03535 1.8e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
PIKHPIBO_03536 4.4e-110 spoIIR S stage II sporulation protein R
PIKHPIBO_03537 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
PIKHPIBO_03539 8e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PIKHPIBO_03540 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PIKHPIBO_03541 5.8e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIKHPIBO_03542 4.4e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
PIKHPIBO_03543 3.6e-158 ywkB S Membrane transport protein
PIKHPIBO_03544 0.0 sfcA 1.1.1.38 C malic enzyme
PIKHPIBO_03545 4.6e-103 tdk 2.7.1.21 F thymidine kinase
PIKHPIBO_03546 1.1e-32 rpmE J Binds the 23S rRNA
PIKHPIBO_03547 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PIKHPIBO_03548 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
PIKHPIBO_03549 7.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIKHPIBO_03550 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PIKHPIBO_03551 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
PIKHPIBO_03552 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
PIKHPIBO_03553 1.7e-93 ywjG S Domain of unknown function (DUF2529)
PIKHPIBO_03554 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PIKHPIBO_03555 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PIKHPIBO_03556 0.0 fadF C COG0247 Fe-S oxidoreductase
PIKHPIBO_03557 1e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PIKHPIBO_03558 1.6e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
PIKHPIBO_03559 4.2e-43 ywjC
PIKHPIBO_03560 0.0 ywjA V ABC transporter
PIKHPIBO_03561 1.1e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIKHPIBO_03562 5.2e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIKHPIBO_03563 1.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
PIKHPIBO_03564 8.7e-96 narJ 1.7.5.1 C nitrate reductase
PIKHPIBO_03565 1.1e-294 narH 1.7.5.1 C Nitrate reductase, beta
PIKHPIBO_03566 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PIKHPIBO_03567 1.3e-84 arfM T cyclic nucleotide binding
PIKHPIBO_03568 2.8e-139 ywiC S YwiC-like protein
PIKHPIBO_03569 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
PIKHPIBO_03570 3.7e-213 narK P COG2223 Nitrate nitrite transporter
PIKHPIBO_03571 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PIKHPIBO_03572 1.1e-42 ywiB S protein conserved in bacteria
PIKHPIBO_03573 2.4e-76 S aspartate phosphatase
PIKHPIBO_03575 2.6e-29 ydcG K sequence-specific DNA binding
PIKHPIBO_03576 5e-33
PIKHPIBO_03577 2e-28 S Domain of unknown function (DUF4177)
PIKHPIBO_03579 3.1e-76 CP Membrane
PIKHPIBO_03582 3.5e-168 speB 3.5.3.11 E Belongs to the arginase family
PIKHPIBO_03583 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PIKHPIBO_03584 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PIKHPIBO_03585 8.5e-83
PIKHPIBO_03586 1.4e-95 ywhD S YwhD family
PIKHPIBO_03587 1.2e-117 ywhC S Peptidase family M50
PIKHPIBO_03588 2.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
PIKHPIBO_03589 5.2e-69 ywhA K Transcriptional regulator
PIKHPIBO_03590 1.3e-246 yhdG_1 E C-terminus of AA_permease
PIKHPIBO_03591 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
PIKHPIBO_03592 7.9e-257 ywfO S COG1078 HD superfamily phosphohydrolases
PIKHPIBO_03593 6.9e-36 ywzC S Belongs to the UPF0741 family
PIKHPIBO_03594 6.6e-110 rsfA_1
PIKHPIBO_03595 8.2e-51 padR K PadR family transcriptional regulator
PIKHPIBO_03596 5.2e-93 S membrane
PIKHPIBO_03597 1.6e-166 V ABC transporter, ATP-binding protein
PIKHPIBO_03598 1.3e-168 yhcI S ABC transporter (permease)
PIKHPIBO_03601 1.2e-185
PIKHPIBO_03603 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PIKHPIBO_03604 6e-163 cysL K Transcriptional regulator
PIKHPIBO_03605 6.2e-158 MA20_14895 S Conserved hypothetical protein 698
PIKHPIBO_03606 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
PIKHPIBO_03607 1.1e-146 ywfI C May function as heme-dependent peroxidase
PIKHPIBO_03608 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
PIKHPIBO_03609 2.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
PIKHPIBO_03610 4.7e-208 bacE EGP Major facilitator Superfamily
PIKHPIBO_03611 2.2e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
PIKHPIBO_03612 1.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PIKHPIBO_03613 3.4e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
PIKHPIBO_03614 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
PIKHPIBO_03615 1.9e-223 ywfA EGP Major facilitator Superfamily
PIKHPIBO_03616 9.9e-206 tcaB EGP Major facilitator Superfamily
PIKHPIBO_03617 1.4e-259 lysP E amino acid
PIKHPIBO_03618 0.0 rocB E arginine degradation protein
PIKHPIBO_03619 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
PIKHPIBO_03620 2.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
PIKHPIBO_03621 6.4e-160 T PhoQ Sensor
PIKHPIBO_03622 9.1e-98 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_03623 1.8e-12 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_03624 1.7e-77
PIKHPIBO_03625 3.2e-119 S ABC-2 family transporter protein
PIKHPIBO_03626 4.3e-172 bcrA5 V ABC transporter, ATP-binding protein
PIKHPIBO_03627 3.5e-87 spsL 5.1.3.13 M Spore Coat
PIKHPIBO_03628 3.6e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PIKHPIBO_03629 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PIKHPIBO_03630 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PIKHPIBO_03631 5.2e-184 spsG M Spore Coat
PIKHPIBO_03632 2.4e-133 spsF M Spore Coat
PIKHPIBO_03633 2.4e-214 spsE 2.5.1.56 M acid synthase
PIKHPIBO_03634 1.9e-158 spsD 2.3.1.210 K Spore Coat
PIKHPIBO_03635 7.4e-222 spsC E Belongs to the DegT DnrJ EryC1 family
PIKHPIBO_03636 3.1e-275 spsB M Capsule polysaccharide biosynthesis protein
PIKHPIBO_03637 2.2e-142 spsA M Spore Coat
PIKHPIBO_03638 2.3e-54 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PIKHPIBO_03639 4.2e-46 ywdK S small membrane protein
PIKHPIBO_03640 1.4e-229 ywdJ F Xanthine uracil
PIKHPIBO_03641 2.5e-37 ywdI S Family of unknown function (DUF5327)
PIKHPIBO_03642 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PIKHPIBO_03643 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
PIKHPIBO_03645 9.9e-88 ywdD
PIKHPIBO_03646 6.3e-57 pex K Transcriptional regulator PadR-like family
PIKHPIBO_03647 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PIKHPIBO_03648 9.7e-20 ywdA
PIKHPIBO_03649 8.6e-281 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
PIKHPIBO_03650 2.4e-248 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PIKHPIBO_03651 2e-07 sacT K transcriptional antiterminator
PIKHPIBO_03652 1.4e-150 sacT K transcriptional antiterminator
PIKHPIBO_03654 0.0 vpr O Belongs to the peptidase S8 family
PIKHPIBO_03655 1.9e-181 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIKHPIBO_03656 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
PIKHPIBO_03657 1.2e-211 rodA D Belongs to the SEDS family
PIKHPIBO_03658 5.4e-79 ysnE K acetyltransferase
PIKHPIBO_03659 3e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
PIKHPIBO_03660 9.9e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
PIKHPIBO_03661 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
PIKHPIBO_03662 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PIKHPIBO_03663 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PIKHPIBO_03664 4.2e-26 ywzA S membrane
PIKHPIBO_03665 9.5e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PIKHPIBO_03666 5e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PIKHPIBO_03667 2.3e-61 gtcA S GtrA-like protein
PIKHPIBO_03668 4.3e-112 ywcC K Bacterial regulatory proteins, tetR family
PIKHPIBO_03670 8e-128 H Methionine biosynthesis protein MetW
PIKHPIBO_03671 5.9e-131 S Streptomycin biosynthesis protein StrF
PIKHPIBO_03672 2.7e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PIKHPIBO_03673 1.6e-238 ywbN P Dyp-type peroxidase family protein
PIKHPIBO_03674 9.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PIKHPIBO_03675 3.7e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PIKHPIBO_03676 8.2e-152 ywbI K Transcriptional regulator
PIKHPIBO_03677 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PIKHPIBO_03678 3.4e-110 ywbG M effector of murein hydrolase
PIKHPIBO_03679 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
PIKHPIBO_03680 3.5e-140 mta K transcriptional
PIKHPIBO_03681 1.9e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
PIKHPIBO_03682 3e-223 ywbD 2.1.1.191 J Methyltransferase
PIKHPIBO_03683 1.1e-65 ywbC 4.4.1.5 E glyoxalase
PIKHPIBO_03684 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIKHPIBO_03685 5.2e-264 epr 3.4.21.62 O Belongs to the peptidase S8 family
PIKHPIBO_03686 1.1e-163 gspA M General stress
PIKHPIBO_03687 2.1e-48 ywaE K Transcriptional regulator
PIKHPIBO_03688 1.3e-195 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PIKHPIBO_03689 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
PIKHPIBO_03690 3.8e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
PIKHPIBO_03691 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
PIKHPIBO_03692 3e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_03693 3.7e-229 dltB M membrane protein involved in D-alanine export
PIKHPIBO_03694 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIKHPIBO_03695 1.8e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PIKHPIBO_03696 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PIKHPIBO_03697 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PIKHPIBO_03698 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
PIKHPIBO_03699 1.4e-248 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIKHPIBO_03700 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
PIKHPIBO_03701 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
PIKHPIBO_03703 6.1e-108 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PIKHPIBO_03704 4.3e-173 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIKHPIBO_03705 3.9e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIKHPIBO_03706 3e-167 cbrA3 P Periplasmic binding protein
PIKHPIBO_03707 1.6e-58 arsR K transcriptional
PIKHPIBO_03708 6.5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PIKHPIBO_03709 5.8e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
PIKHPIBO_03710 1.9e-47 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
PIKHPIBO_03711 1.1e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIKHPIBO_03712 1.6e-287 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PIKHPIBO_03713 5.3e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
PIKHPIBO_03714 8.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
PIKHPIBO_03715 9.2e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
PIKHPIBO_03716 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PIKHPIBO_03717 1.6e-193 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PIKHPIBO_03718 1e-251 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
PIKHPIBO_03719 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PIKHPIBO_03720 5e-291 cydD V ATP-binding protein
PIKHPIBO_03721 0.0 cydD V ATP-binding
PIKHPIBO_03722 5.5e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
PIKHPIBO_03723 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
PIKHPIBO_03724 1.5e-215 cimH C COG3493 Na citrate symporter
PIKHPIBO_03725 6e-157 yxkH G Polysaccharide deacetylase
PIKHPIBO_03726 1e-204 msmK P Belongs to the ABC transporter superfamily
PIKHPIBO_03727 8.3e-165 lrp QT PucR C-terminal helix-turn-helix domain
PIKHPIBO_03728 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIKHPIBO_03729 3.8e-87 yxkC S Domain of unknown function (DUF4352)
PIKHPIBO_03730 3.9e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PIKHPIBO_03731 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PIKHPIBO_03734 3.5e-85 yxjI S LURP-one-related
PIKHPIBO_03735 6.3e-218 yxjG 2.1.1.14 E Methionine synthase
PIKHPIBO_03736 1.5e-155 rlmA 2.1.1.187 Q Methyltransferase domain
PIKHPIBO_03737 1.1e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PIKHPIBO_03738 2.7e-75 T Domain of unknown function (DUF4163)
PIKHPIBO_03739 7.4e-46 yxiS
PIKHPIBO_03740 1.1e-177 L DNA synthesis involved in DNA repair
PIKHPIBO_03741 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
PIKHPIBO_03742 1.6e-222 citH C Citrate transporter
PIKHPIBO_03743 5.2e-141 exoK GH16 M licheninase activity
PIKHPIBO_03744 1.5e-144 licT K transcriptional antiterminator
PIKHPIBO_03745 9.3e-223 yxiO S COG2270 Permeases of the major facilitator superfamily
PIKHPIBO_03746 3.1e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
PIKHPIBO_03747 5.5e-200 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
PIKHPIBO_03748 4.7e-147 yxxF EG EamA-like transporter family
PIKHPIBO_03749 3.7e-73 yxiE T Belongs to the universal stress protein A family
PIKHPIBO_03750 0.0 L HKD family nuclease
PIKHPIBO_03751 1.1e-60 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PIKHPIBO_03752 9.6e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
PIKHPIBO_03753 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
PIKHPIBO_03754 7.3e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
PIKHPIBO_03755 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PIKHPIBO_03756 1.5e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
PIKHPIBO_03757 1.5e-177 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
PIKHPIBO_03758 2e-253 lysP E amino acid
PIKHPIBO_03759 5.1e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
PIKHPIBO_03760 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PIKHPIBO_03761 2.7e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PIKHPIBO_03762 4.8e-171 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PIKHPIBO_03763 4e-150 yidA S hydrolases of the HAD superfamily
PIKHPIBO_03766 2.3e-07 yxeE
PIKHPIBO_03767 8.4e-23 yxeD
PIKHPIBO_03768 6e-35
PIKHPIBO_03769 5.9e-177 fhuD P Periplasmic binding protein
PIKHPIBO_03770 1.3e-57 yxeA S Protein of unknown function (DUF1093)
PIKHPIBO_03771 0.0 yxdM V ABC transporter (permease)
PIKHPIBO_03772 5.5e-141 yxdL V ABC transporter, ATP-binding protein
PIKHPIBO_03773 1e-176 T PhoQ Sensor
PIKHPIBO_03774 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_03775 3.3e-272 T Histidine kinase
PIKHPIBO_03776 9.1e-138 T Transcriptional regulator
PIKHPIBO_03777 1.3e-162 bcrA V ABC transporter, ATP-binding protein
PIKHPIBO_03778 1.3e-131 S permease
PIKHPIBO_03779 3.9e-128 S ABC-2 family transporter protein
PIKHPIBO_03780 5.1e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
PIKHPIBO_03781 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
PIKHPIBO_03782 1.1e-166 iolH G Xylose isomerase-like TIM barrel
PIKHPIBO_03783 2.3e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PIKHPIBO_03784 2.5e-231 iolF EGP Major facilitator Superfamily
PIKHPIBO_03785 6.5e-178 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PIKHPIBO_03786 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PIKHPIBO_03787 4.8e-182 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PIKHPIBO_03788 7.6e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PIKHPIBO_03789 2.1e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PIKHPIBO_03790 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
PIKHPIBO_03791 4.9e-176 iolS C Aldo keto reductase
PIKHPIBO_03792 6.7e-246 csbC EGP Major facilitator Superfamily
PIKHPIBO_03793 0.0 htpG O Molecular chaperone. Has ATPase activity
PIKHPIBO_03795 2.1e-151 IQ Enoyl-(Acyl carrier protein) reductase
PIKHPIBO_03796 3.5e-103 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIKHPIBO_03797 2.9e-199 desK 2.7.13.3 T Histidine kinase
PIKHPIBO_03798 1.8e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
PIKHPIBO_03799 4.1e-217 yxbF K Bacterial regulatory proteins, tetR family
PIKHPIBO_03800 2.5e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
PIKHPIBO_03801 1.1e-141 S PQQ-like domain
PIKHPIBO_03802 1.9e-63 S Family of unknown function (DUF5391)
PIKHPIBO_03803 1.7e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
PIKHPIBO_03804 2.9e-202 EGP Major facilitator Superfamily
PIKHPIBO_03805 1.5e-74 yxaI S membrane protein domain
PIKHPIBO_03806 2.4e-119 E Ring-cleavage extradiol dioxygenase
PIKHPIBO_03807 7.8e-22 3.4.24.84 O metalloendopeptidase activity
PIKHPIBO_03808 4.7e-91 mrr V Mrr N-terminal domain
PIKHPIBO_03809 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
PIKHPIBO_03810 2.3e-287 ahpF O Alkyl hydroperoxide reductase
PIKHPIBO_03811 1.6e-227 XK27_00240 S Fic/DOC family
PIKHPIBO_03812 3.2e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
PIKHPIBO_03813 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
PIKHPIBO_03814 9.8e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
PIKHPIBO_03815 1.6e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
PIKHPIBO_03816 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PIKHPIBO_03817 2e-88 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
PIKHPIBO_03818 3.7e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PIKHPIBO_03819 1.2e-180 S Fusaric acid resistance protein-like
PIKHPIBO_03820 1.1e-18
PIKHPIBO_03821 2.2e-77 K SIR2-like domain
PIKHPIBO_03822 4.1e-96 D AAA domain
PIKHPIBO_03823 4.8e-93
PIKHPIBO_03824 2.6e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PIKHPIBO_03825 7.9e-08 S YyzF-like protein
PIKHPIBO_03827 4.9e-218 yycP
PIKHPIBO_03828 6.6e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PIKHPIBO_03829 2.5e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
PIKHPIBO_03830 3.7e-87 yycN 2.3.1.128 K Acetyltransferase
PIKHPIBO_03832 1.3e-199 S Histidine kinase
PIKHPIBO_03833 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
PIKHPIBO_03834 5e-257 rocE E amino acid
PIKHPIBO_03835 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
PIKHPIBO_03836 2.4e-259 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PIKHPIBO_03837 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
PIKHPIBO_03838 3e-306 S ABC transporter
PIKHPIBO_03839 4.5e-195 S Major Facilitator Superfamily
PIKHPIBO_03840 7.7e-260
PIKHPIBO_03841 1.3e-190 2.7.7.73, 2.7.7.80 H ThiF family
PIKHPIBO_03842 4.1e-251 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
PIKHPIBO_03843 2.2e-93 K PFAM response regulator receiver
PIKHPIBO_03844 2.1e-62 S Peptidase propeptide and YPEB domain
PIKHPIBO_03845 4.6e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PIKHPIBO_03846 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PIKHPIBO_03847 1.9e-150 yycI S protein conserved in bacteria
PIKHPIBO_03848 1.6e-260 yycH S protein conserved in bacteria
PIKHPIBO_03849 0.0 vicK 2.7.13.3 T Histidine kinase
PIKHPIBO_03850 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIKHPIBO_03855 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PIKHPIBO_03856 9.1e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIKHPIBO_03857 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PIKHPIBO_03858 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
PIKHPIBO_03860 3.5e-17 yycC K YycC-like protein
PIKHPIBO_03861 2.3e-37 M 4-amino-4-deoxy-L-arabinose transferase activity
PIKHPIBO_03862 1.7e-240 M Glycosyltransferase Family 4
PIKHPIBO_03863 5.1e-206 S Ecdysteroid kinase
PIKHPIBO_03864 9.1e-236 S Carbamoyl-phosphate synthase L chain, ATP binding domain
PIKHPIBO_03865 3.5e-236 M Glycosyltransferase Family 4
PIKHPIBO_03866 2.7e-120 S GlcNAc-PI de-N-acetylase
PIKHPIBO_03867 3.6e-89 KLT COG0515 Serine threonine protein kinase
PIKHPIBO_03868 4.9e-73 rplI J binds to the 23S rRNA
PIKHPIBO_03869 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PIKHPIBO_03870 5.4e-159 yybS S membrane
PIKHPIBO_03872 6.5e-85 cotF M Spore coat protein
PIKHPIBO_03873 2.8e-66 ydeP3 K Transcriptional regulator
PIKHPIBO_03874 8.6e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
PIKHPIBO_03875 8.2e-166 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PIKHPIBO_03876 6.5e-273 sacB 2.4.1.10 GH68 M levansucrase activity
PIKHPIBO_03877 4.9e-309 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
PIKHPIBO_03878 1.5e-115 K FCD domain
PIKHPIBO_03879 5.4e-76 dinB S PFAM DinB family protein
PIKHPIBO_03880 5.8e-161 G Major Facilitator Superfamily
PIKHPIBO_03881 7.3e-84 yijE EG EamA-like transporter family
PIKHPIBO_03882 2.9e-24 K MerR HTH family regulatory protein
PIKHPIBO_03883 3.3e-158 yfiE K LysR substrate binding domain
PIKHPIBO_03884 1.3e-99 E LysE type translocator
PIKHPIBO_03885 1.3e-189 ynfM EGP Major facilitator Superfamily
PIKHPIBO_03886 3.9e-159 gltC K Transcriptional regulator
PIKHPIBO_03887 1.4e-54 ypaA S Protein of unknown function (DUF1304)
PIKHPIBO_03888 9.6e-115 drgA C nitroreductase
PIKHPIBO_03889 4.1e-69 ydgJ K Winged helix DNA-binding domain
PIKHPIBO_03890 1.4e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
PIKHPIBO_03891 1e-76 yybA 2.3.1.57 K transcriptional
PIKHPIBO_03892 2.7e-76 yjcF S Acetyltransferase (GNAT) domain
PIKHPIBO_03893 2.6e-163 eaeH M Domain of Unknown Function (DUF1259)
PIKHPIBO_03894 5.4e-41 3.1.3.18 S glycolate biosynthetic process
PIKHPIBO_03895 1.7e-46 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
PIKHPIBO_03896 3.1e-60 S Pyridine nucleotide-disulphide oxidoreductase
PIKHPIBO_03897 1.6e-250 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIKHPIBO_03898 4e-130 ydfC EG EamA-like transporter family
PIKHPIBO_03900 8.2e-25 V VanZ like family
PIKHPIBO_03901 1.6e-27
PIKHPIBO_03902 1.2e-30 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
PIKHPIBO_03903 4.5e-54 L Recombinase
PIKHPIBO_03904 9.2e-119 S response regulator aspartate phosphatase
PIKHPIBO_03905 6.5e-54
PIKHPIBO_03906 7.5e-08
PIKHPIBO_03907 8.8e-55 S Domain of unknown function with cystatin-like fold (DUF4467)
PIKHPIBO_03908 1.5e-41 yddI
PIKHPIBO_03909 9.1e-160 yddH CBM50 M Lysozyme-like
PIKHPIBO_03910 3.2e-200 yddG S maturation of SSU-rRNA
PIKHPIBO_03911 1.2e-36 S Domain of unknown function (DUF1874)
PIKHPIBO_03912 0.0 yddE S AAA-like domain
PIKHPIBO_03913 1.6e-75 yddD S TcpE family
PIKHPIBO_03914 6.8e-24 yddC
PIKHPIBO_03915 5.3e-126 yddB S Conjugative transposon protein TcpC
PIKHPIBO_03917 5.4e-39 yddA
PIKHPIBO_03922 1.4e-36
PIKHPIBO_03923 6.3e-180 nicK L Replication initiation factor
PIKHPIBO_03924 1.2e-239 ydcQ D Ftsk spoiiie family protein
PIKHPIBO_03925 6e-68
PIKHPIBO_03926 1.6e-37 S Bacterial protein of unknown function (DUF961)
PIKHPIBO_03928 1.1e-24
PIKHPIBO_03929 3.6e-09
PIKHPIBO_03930 2.7e-32 yvaO K Transcriptional
PIKHPIBO_03931 6.6e-39 immA E Pfam:DUF955
PIKHPIBO_03932 5.1e-36
PIKHPIBO_03933 1.6e-60
PIKHPIBO_03934 7e-22 yyaL O Highly conserved protein containing a thioredoxin domain
PIKHPIBO_03935 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
PIKHPIBO_03936 5e-162 yyaK S CAAX protease self-immunity
PIKHPIBO_03937 2e-247 ydjK G Sugar (and other) transporter
PIKHPIBO_03938 2.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PIKHPIBO_03939 9.6e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
PIKHPIBO_03940 1.5e-143 xth 3.1.11.2 L exodeoxyribonuclease III
PIKHPIBO_03941 3.8e-99 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PIKHPIBO_03942 4.8e-105 adaA 3.2.2.21 K Transcriptional regulator
PIKHPIBO_03943 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PIKHPIBO_03944 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIKHPIBO_03945 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
PIKHPIBO_03946 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PIKHPIBO_03947 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PIKHPIBO_03948 2.3e-33 yyzM S protein conserved in bacteria
PIKHPIBO_03949 2.4e-176 yyaD S Membrane
PIKHPIBO_03950 6.2e-111 yyaC S Sporulation protein YyaC
PIKHPIBO_03951 5.1e-148 spo0J K Belongs to the ParB family
PIKHPIBO_03952 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
PIKHPIBO_03953 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PIKHPIBO_03954 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PIKHPIBO_03955 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PIKHPIBO_03956 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PIKHPIBO_03957 3.5e-109 jag S single-stranded nucleic acid binding R3H
PIKHPIBO_03958 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIKHPIBO_03959 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)