ORF_ID e_value Gene_name EC_number CAZy COGs Description
HFOGIIHM_00001 1.8e-68
HFOGIIHM_00002 1.7e-238 pgaC GT2 M Glycosyl transferase
HFOGIIHM_00003 9.1e-139 T EAL domain
HFOGIIHM_00005 7.6e-82 L Integrase
HFOGIIHM_00006 3.6e-31 lytE M LysM domain protein
HFOGIIHM_00007 3.6e-58 tdk 2.7.1.21 F Thymidine kinase
HFOGIIHM_00009 2.3e-34 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HFOGIIHM_00010 1.8e-30
HFOGIIHM_00014 4.6e-07
HFOGIIHM_00022 2.2e-31 S Protein of unknown function (DUF1064)
HFOGIIHM_00023 3.7e-63 S DNA ligase (ATP) activity
HFOGIIHM_00025 1.6e-59 dnaE_2 2.7.7.7 L DNA polymerase
HFOGIIHM_00026 3.4e-44 1.1.98.6, 3.6.3.14, 3.6.3.15, 4.1.1.35 L Participates in initiation and elongation during chromosome replication
HFOGIIHM_00027 1.3e-152 dnaE_2 2.7.7.7 L DNA polymerase
HFOGIIHM_00028 4.1e-42 S PD-(D/E)XK nuclease superfamily
HFOGIIHM_00029 1e-36 S DNA primase activity
HFOGIIHM_00030 4.5e-103 M Glycosyl hydrolases family 25
HFOGIIHM_00031 3e-11 S DNA binding
HFOGIIHM_00032 2.6e-09
HFOGIIHM_00035 1.2e-07
HFOGIIHM_00036 9.2e-106 fliC N bacterial-type flagellum-dependent cell motility
HFOGIIHM_00037 1.1e-67
HFOGIIHM_00038 2.7e-52
HFOGIIHM_00040 2.2e-55 D Phage-related minor tail protein
HFOGIIHM_00041 4.7e-79 xerH L Belongs to the 'phage' integrase family
HFOGIIHM_00044 1.4e-11 hol S COG5546 Small integral membrane protein
HFOGIIHM_00046 1.3e-07
HFOGIIHM_00048 1.6e-17
HFOGIIHM_00049 2.8e-34 GT2,GT4 O gp58-like protein
HFOGIIHM_00050 2.1e-29
HFOGIIHM_00056 3e-162 tnpB L Putative transposase DNA-binding domain
HFOGIIHM_00057 1e-62
HFOGIIHM_00059 9.1e-56
HFOGIIHM_00060 8.2e-35
HFOGIIHM_00061 2.8e-138 gp17a S Terminase-like family
HFOGIIHM_00062 3.4e-27 1.1.98.6, 3.6.3.14, 3.6.3.15, 4.1.1.35 L Participates in initiation and elongation during chromosome replication
HFOGIIHM_00063 1.1e-08 gp17a S Terminase-like family
HFOGIIHM_00064 1.1e-16
HFOGIIHM_00069 1.8e-12 S Replication initiator protein A (RepA) N-terminus
HFOGIIHM_00070 2.1e-94 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HFOGIIHM_00072 6e-41
HFOGIIHM_00088 2e-08 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFOGIIHM_00094 6.8e-09
HFOGIIHM_00096 8.5e-11
HFOGIIHM_00097 7.7e-41 doc S Fic/DOC family
HFOGIIHM_00101 1.8e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFOGIIHM_00102 3.5e-35
HFOGIIHM_00104 1.2e-163 L transposase, IS605 OrfB family
HFOGIIHM_00105 3e-81 L Belongs to the 'phage' integrase family
HFOGIIHM_00107 1.5e-10 2.7.1.24 H dephospho-CoA kinase activity
HFOGIIHM_00109 3.7e-16
HFOGIIHM_00110 4.3e-21 L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFOGIIHM_00111 1.9e-163 tnpB L Putative transposase DNA-binding domain
HFOGIIHM_00112 8.5e-70 S hydrolase activity
HFOGIIHM_00113 8.8e-33
HFOGIIHM_00115 3.6e-96 3.6.4.12 L DnaB-like helicase C terminal domain
HFOGIIHM_00118 5.8e-122 recD 3.1.11.5 L Helix-hairpin-helix containing domain
HFOGIIHM_00123 4.1e-115 pnuC H nicotinamide mononucleotide transporter
HFOGIIHM_00133 1e-24 S RNA ligase
HFOGIIHM_00134 3.6e-46
HFOGIIHM_00135 1.2e-71 dck 2.7.1.74 F deoxynucleoside kinase
HFOGIIHM_00150 8.1e-55 ntd 2.4.2.6 F Nucleoside
HFOGIIHM_00157 4.7e-69 pldB 3.1.1.5 I Serine aminopeptidase, S33
HFOGIIHM_00158 1.9e-56 2.7.7.65 T GGDEF domain
HFOGIIHM_00159 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFOGIIHM_00160 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFOGIIHM_00161 7.1e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HFOGIIHM_00162 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFOGIIHM_00164 3.5e-16 L Transposase
HFOGIIHM_00165 2.2e-255 L Transposase
HFOGIIHM_00166 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFOGIIHM_00167 1.3e-46 glpT G Major Facilitator Superfamily
HFOGIIHM_00168 3.7e-157 glpT G Major Facilitator Superfamily
HFOGIIHM_00169 8.8e-15
HFOGIIHM_00171 3.1e-170 whiA K May be required for sporulation
HFOGIIHM_00172 4.2e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HFOGIIHM_00173 1.7e-162 rapZ S Displays ATPase and GTPase activities
HFOGIIHM_00174 2.4e-245 steT E amino acid
HFOGIIHM_00175 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFOGIIHM_00176 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFOGIIHM_00177 1.5e-13
HFOGIIHM_00178 2.3e-116 yfbR S HD containing hydrolase-like enzyme
HFOGIIHM_00179 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFOGIIHM_00180 9.1e-84 ykhA 3.1.2.20 I Thioesterase superfamily
HFOGIIHM_00181 1.6e-165 aatB ET PFAM extracellular solute-binding protein, family 3
HFOGIIHM_00182 7.6e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HFOGIIHM_00183 4.6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFOGIIHM_00184 1.9e-169 lutA C Cysteine-rich domain
HFOGIIHM_00185 1.3e-295 lutB C 4Fe-4S dicluster domain
HFOGIIHM_00186 2.4e-138 yrjD S LUD domain
HFOGIIHM_00187 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HFOGIIHM_00188 2.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HFOGIIHM_00189 1.3e-159 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFOGIIHM_00190 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFOGIIHM_00191 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HFOGIIHM_00192 2.4e-32 KT PspC domain protein
HFOGIIHM_00193 1.6e-79 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFOGIIHM_00194 1.1e-77 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFOGIIHM_00195 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFOGIIHM_00196 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFOGIIHM_00197 9e-124 comFC S Competence protein
HFOGIIHM_00198 2.3e-259 comFA L Helicase C-terminal domain protein
HFOGIIHM_00199 2.6e-112 yvyE 3.4.13.9 S YigZ family
HFOGIIHM_00200 1.3e-249 EGP Major facilitator Superfamily
HFOGIIHM_00201 3.3e-68 rmaI K Transcriptional regulator
HFOGIIHM_00202 9.2e-40
HFOGIIHM_00203 0.0 ydaO E amino acid
HFOGIIHM_00204 4.3e-305 ybeC E amino acid
HFOGIIHM_00205 4.2e-86 S Aminoacyl-tRNA editing domain
HFOGIIHM_00206 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFOGIIHM_00207 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFOGIIHM_00209 6.3e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFOGIIHM_00210 0.0 uup S ABC transporter, ATP-binding protein
HFOGIIHM_00211 1.7e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFOGIIHM_00212 4.3e-230 mtnE 2.6.1.83 E Aminotransferase
HFOGIIHM_00213 3.6e-148 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HFOGIIHM_00214 1.4e-139 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFOGIIHM_00215 3.9e-229 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFOGIIHM_00216 2.9e-134 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFOGIIHM_00217 1.9e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFOGIIHM_00218 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HFOGIIHM_00219 1.1e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HFOGIIHM_00220 7.8e-58 L Helix-turn-helix domain
HFOGIIHM_00221 5.1e-57 L Helix-turn-helix domain
HFOGIIHM_00222 7.3e-85 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFOGIIHM_00223 1.5e-71 ypuA S Protein of unknown function (DUF1002)
HFOGIIHM_00224 9.2e-45 S Putative peptidoglycan binding domain
HFOGIIHM_00225 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
HFOGIIHM_00226 3.3e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HFOGIIHM_00227 2.6e-119 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HFOGIIHM_00228 3.3e-166 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HFOGIIHM_00229 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HFOGIIHM_00230 4.8e-232 ndh 1.6.99.3 C NADH dehydrogenase
HFOGIIHM_00231 9.4e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HFOGIIHM_00232 1.2e-122 radC L DNA repair protein
HFOGIIHM_00233 3.9e-179 mreB D cell shape determining protein MreB
HFOGIIHM_00234 5.9e-152 mreC M Involved in formation and maintenance of cell shape
HFOGIIHM_00235 8.7e-93 mreD M rod shape-determining protein MreD
HFOGIIHM_00236 3.2e-102 glnP P ABC transporter permease
HFOGIIHM_00237 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFOGIIHM_00238 1.5e-160 aatB ET ABC transporter substrate-binding protein
HFOGIIHM_00239 2.1e-230 ymfF S Peptidase M16 inactive domain protein
HFOGIIHM_00240 2.4e-250 ymfH S Peptidase M16
HFOGIIHM_00241 2.5e-141 ymfM S Helix-turn-helix domain
HFOGIIHM_00242 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFOGIIHM_00243 3.4e-233 cinA 3.5.1.42 S Belongs to the CinA family
HFOGIIHM_00244 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFOGIIHM_00245 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
HFOGIIHM_00246 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFOGIIHM_00247 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFOGIIHM_00248 1.8e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFOGIIHM_00249 1.2e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFOGIIHM_00250 2.2e-204 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFOGIIHM_00251 1.5e-29 yajC U Preprotein translocase
HFOGIIHM_00252 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HFOGIIHM_00253 6.4e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFOGIIHM_00254 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFOGIIHM_00255 4.1e-43 yrzL S Belongs to the UPF0297 family
HFOGIIHM_00256 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFOGIIHM_00257 6.1e-48 yrzB S Belongs to the UPF0473 family
HFOGIIHM_00258 1.6e-86 cvpA S Colicin V production protein
HFOGIIHM_00259 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFOGIIHM_00260 6.1e-54 trxA O Belongs to the thioredoxin family
HFOGIIHM_00261 4.1e-98 yslB S Protein of unknown function (DUF2507)
HFOGIIHM_00262 1.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HFOGIIHM_00263 1.8e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFOGIIHM_00264 2.1e-96 S Phosphoesterase
HFOGIIHM_00265 2.7e-76 ykuL S (CBS) domain
HFOGIIHM_00266 1.2e-154 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HFOGIIHM_00267 2.1e-149 ykuT M mechanosensitive ion channel
HFOGIIHM_00268 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFOGIIHM_00269 1.8e-14
HFOGIIHM_00270 1.2e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFOGIIHM_00271 4.5e-183 ccpA K catabolite control protein A
HFOGIIHM_00272 1.8e-137
HFOGIIHM_00273 1.7e-131 yebC K Transcriptional regulatory protein
HFOGIIHM_00274 2.1e-42 O Bacterial dnaA protein
HFOGIIHM_00275 6e-18 L PFAM Integrase catalytic region
HFOGIIHM_00276 6.2e-260 S Putative peptidoglycan binding domain
HFOGIIHM_00277 1.8e-39
HFOGIIHM_00278 7.8e-214 bacI V MacB-like periplasmic core domain
HFOGIIHM_00279 2.8e-128 V ABC transporter
HFOGIIHM_00280 2.8e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFOGIIHM_00281 9.8e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HFOGIIHM_00282 5.4e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFOGIIHM_00283 1.9e-149 E Glyoxalase-like domain
HFOGIIHM_00284 7.5e-155 glcU U sugar transport
HFOGIIHM_00285 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HFOGIIHM_00286 2.9e-96 S reductase
HFOGIIHM_00288 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFOGIIHM_00289 1.3e-176 ABC-SBP S ABC transporter
HFOGIIHM_00290 3.5e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HFOGIIHM_00291 4.7e-214 htrA 3.4.21.107 O serine protease
HFOGIIHM_00292 2.3e-153 vicX 3.1.26.11 S domain protein
HFOGIIHM_00293 7.8e-149 yycI S YycH protein
HFOGIIHM_00294 2.4e-245 yycH S YycH protein
HFOGIIHM_00295 0.0 vicK 2.7.13.3 T Histidine kinase
HFOGIIHM_00296 3.1e-130 K response regulator
HFOGIIHM_00298 1.3e-307 lmrA 3.6.3.44 V ABC transporter
HFOGIIHM_00299 1.4e-72 K helix_turn_helix multiple antibiotic resistance protein
HFOGIIHM_00301 3.1e-101 K DNA-binding helix-turn-helix protein
HFOGIIHM_00302 2.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HFOGIIHM_00303 1.5e-60
HFOGIIHM_00304 1.2e-190 yttB EGP Major facilitator Superfamily
HFOGIIHM_00305 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HFOGIIHM_00306 2e-74 rplI J Binds to the 23S rRNA
HFOGIIHM_00307 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HFOGIIHM_00308 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFOGIIHM_00309 7.5e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFOGIIHM_00310 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HFOGIIHM_00311 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFOGIIHM_00312 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFOGIIHM_00313 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFOGIIHM_00314 1.7e-34 yaaA S S4 domain protein YaaA
HFOGIIHM_00315 2.9e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFOGIIHM_00316 1.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFOGIIHM_00317 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HFOGIIHM_00318 2.7e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFOGIIHM_00319 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFOGIIHM_00320 4.1e-136 jag S R3H domain protein
HFOGIIHM_00321 5.3e-56 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFOGIIHM_00322 3.5e-42 ybaN S Protein of unknown function (DUF454)
HFOGIIHM_00323 2e-28 S Protein of unknown function (DUF3290)
HFOGIIHM_00324 1.9e-29 S Protein of unknown function (DUF3290)
HFOGIIHM_00325 4.3e-115 yviA S Protein of unknown function (DUF421)
HFOGIIHM_00326 1.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HFOGIIHM_00327 7.5e-21
HFOGIIHM_00328 3.1e-89 ntd 2.4.2.6 F Nucleoside
HFOGIIHM_00329 3.7e-159 3.1.3.102, 3.1.3.104 S hydrolase
HFOGIIHM_00330 2.3e-36 S Lipopolysaccharide assembly protein A domain
HFOGIIHM_00332 1.4e-134 L Belongs to the 'phage' integrase family
HFOGIIHM_00333 1.9e-95 dam2 2.1.1.72 L DNA methyltransferase
HFOGIIHM_00334 1.5e-112 S AAA ATPase domain
HFOGIIHM_00335 3.5e-15
HFOGIIHM_00337 1.8e-79 3.4.21.88 K Peptidase S24-like
HFOGIIHM_00338 2.8e-10 K Helix-turn-helix XRE-family like proteins
HFOGIIHM_00341 5.2e-56
HFOGIIHM_00342 8e-15
HFOGIIHM_00345 9.1e-119 L DnaD domain protein
HFOGIIHM_00346 1.4e-86 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HFOGIIHM_00347 2.1e-16 L Belongs to the 'phage' integrase family
HFOGIIHM_00349 2e-68
HFOGIIHM_00350 6.1e-129
HFOGIIHM_00352 3.8e-17
HFOGIIHM_00356 7.2e-83 arpU S Phage transcriptional regulator, ArpU family
HFOGIIHM_00357 8.7e-09
HFOGIIHM_00360 4.9e-08
HFOGIIHM_00361 1.5e-150 L HNH nucleases
HFOGIIHM_00362 1.4e-75 terS L Phage terminase, small subunit
HFOGIIHM_00363 0.0 terL S overlaps another CDS with the same product name
HFOGIIHM_00366 1.9e-239 S Phage portal protein
HFOGIIHM_00367 5.4e-113 pi136 S Caudovirus prohead serine protease
HFOGIIHM_00368 2e-208 S Phage capsid family
HFOGIIHM_00369 8.8e-69 S Phage gp6-like head-tail connector protein
HFOGIIHM_00370 1.5e-39 S Phage head-tail joining protein
HFOGIIHM_00371 1.5e-62 S Bacteriophage HK97-gp10, putative tail-component
HFOGIIHM_00372 1.7e-75
HFOGIIHM_00373 3.4e-112
HFOGIIHM_00374 2.7e-23
HFOGIIHM_00375 1.5e-19
HFOGIIHM_00376 0.0 M Phage tail tape measure protein TP901
HFOGIIHM_00377 1.6e-154 S Phage tail protein
HFOGIIHM_00378 1.2e-250 3.4.24.40 M Peptidase family M23
HFOGIIHM_00380 2.1e-42 S Calcineurin-like phosphoesterase
HFOGIIHM_00381 8.3e-82 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HFOGIIHM_00382 6.1e-26 S GDSL-like Lipase/Acylhydrolase
HFOGIIHM_00386 1.6e-32
HFOGIIHM_00387 6.9e-34 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HFOGIIHM_00388 4.6e-189 ps461 3.5.1.104 M hydrolase, family 25
HFOGIIHM_00389 5.1e-16
HFOGIIHM_00391 1.9e-158 1.6.5.2 GM NAD(P)H-binding
HFOGIIHM_00392 2e-74 K Transcriptional regulator
HFOGIIHM_00393 7e-164 proX M ABC transporter, substrate-binding protein, QAT family
HFOGIIHM_00394 9.7e-110 proWZ P ABC transporter permease
HFOGIIHM_00395 1.3e-142 proV E ABC transporter, ATP-binding protein
HFOGIIHM_00396 5.8e-104 proW P ABC transporter, permease protein
HFOGIIHM_00397 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HFOGIIHM_00398 4.9e-254 clcA P chloride
HFOGIIHM_00399 4.4e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HFOGIIHM_00400 3.1e-103 metI P ABC transporter permease
HFOGIIHM_00401 2.1e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFOGIIHM_00402 1.9e-155 metQ1 P Belongs to the nlpA lipoprotein family
HFOGIIHM_00403 3.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HFOGIIHM_00404 9.2e-220 norA EGP Major facilitator Superfamily
HFOGIIHM_00405 8.3e-39 1.3.5.4 S FMN binding
HFOGIIHM_00406 2.1e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFOGIIHM_00407 1.6e-266 yfnA E amino acid
HFOGIIHM_00408 1.2e-238 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFOGIIHM_00410 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFOGIIHM_00411 0.0 helD 3.6.4.12 L DNA helicase
HFOGIIHM_00412 1.7e-81 ndk 2.7.4.6 F Belongs to the NDK family
HFOGIIHM_00413 1.3e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HFOGIIHM_00414 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFOGIIHM_00415 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HFOGIIHM_00416 6.5e-232 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HFOGIIHM_00417 1.1e-178
HFOGIIHM_00418 4.2e-132 cobB K SIR2 family
HFOGIIHM_00420 7.4e-163 yunF F Protein of unknown function DUF72
HFOGIIHM_00421 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFOGIIHM_00422 6.4e-156 tatD L hydrolase, TatD family
HFOGIIHM_00423 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFOGIIHM_00424 9.5e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFOGIIHM_00425 6.8e-37 veg S Biofilm formation stimulator VEG
HFOGIIHM_00426 2e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFOGIIHM_00427 2.8e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
HFOGIIHM_00428 3.2e-121 fhuC P ABC transporter
HFOGIIHM_00429 2.3e-126 znuB U ABC 3 transport family
HFOGIIHM_00430 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HFOGIIHM_00431 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFOGIIHM_00432 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFOGIIHM_00433 6.8e-48
HFOGIIHM_00436 1.8e-223 P ammonium transporter
HFOGIIHM_00437 8.6e-98 ureI S AmiS/UreI family transporter
HFOGIIHM_00438 4e-47 ureA 3.5.1.5 E Urease, gamma subunit
HFOGIIHM_00439 2.9e-63 ureB 3.5.1.5 E Urease beta subunit
HFOGIIHM_00440 0.0 ureC 3.5.1.5 E Amidohydrolase family
HFOGIIHM_00441 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HFOGIIHM_00442 1.9e-132 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HFOGIIHM_00443 3.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HFOGIIHM_00444 9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HFOGIIHM_00445 4.9e-42 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFOGIIHM_00446 2e-73 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFOGIIHM_00447 2.1e-185 nikMN P PDGLE domain
HFOGIIHM_00448 8.5e-135 P Cobalt transport protein
HFOGIIHM_00449 3.8e-136 cbiO P ABC transporter
HFOGIIHM_00450 2.8e-131 K Transcriptional regulatory protein, C-terminal domain protein
HFOGIIHM_00451 1.9e-158 pstS P Phosphate
HFOGIIHM_00452 5.8e-150 pstC P probably responsible for the translocation of the substrate across the membrane
HFOGIIHM_00453 7.9e-152 pstA P Phosphate transport system permease protein PstA
HFOGIIHM_00454 1.4e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFOGIIHM_00455 3.9e-125 phoU P Plays a role in the regulation of phosphate uptake
HFOGIIHM_00456 1.7e-135
HFOGIIHM_00457 1.2e-241 ydaM M Glycosyl transferase
HFOGIIHM_00458 2.8e-218 G Glycosyl hydrolases family 8
HFOGIIHM_00459 7.3e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HFOGIIHM_00460 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HFOGIIHM_00461 8.1e-241 ktrB P Potassium uptake protein
HFOGIIHM_00462 7.7e-115 ktrA P domain protein
HFOGIIHM_00463 1.9e-79 Q Methyltransferase
HFOGIIHM_00464 3.3e-231 mntH P H( )-stimulated, divalent metal cation uptake system
HFOGIIHM_00465 5.2e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HFOGIIHM_00466 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HFOGIIHM_00467 1.2e-94 S NADPH-dependent FMN reductase
HFOGIIHM_00468 8e-180 MA20_14895 S Conserved hypothetical protein 698
HFOGIIHM_00469 4.5e-137 I alpha/beta hydrolase fold
HFOGIIHM_00470 3e-162 lsa S ABC transporter
HFOGIIHM_00471 6.1e-102 lsa S ABC transporter
HFOGIIHM_00472 3e-181 yfeX P Peroxidase
HFOGIIHM_00473 1.5e-275 arcD S C4-dicarboxylate anaerobic carrier
HFOGIIHM_00474 6.4e-262 ytjP 3.5.1.18 E Dipeptidase
HFOGIIHM_00475 7e-215 uhpT EGP Major facilitator Superfamily
HFOGIIHM_00476 1.2e-282 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HFOGIIHM_00477 3.7e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFOGIIHM_00478 1.8e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HFOGIIHM_00479 4.8e-238 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HFOGIIHM_00480 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HFOGIIHM_00481 1.9e-172 deoR K sugar-binding domain protein
HFOGIIHM_00482 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFOGIIHM_00483 3.8e-125 K response regulator
HFOGIIHM_00484 2e-203 hpk31 2.7.13.3 T Histidine kinase
HFOGIIHM_00485 9.7e-137 azlC E AzlC protein
HFOGIIHM_00486 1.6e-52 azlD S branched-chain amino acid
HFOGIIHM_00487 2.9e-115 K DNA-binding transcription factor activity
HFOGIIHM_00488 4.4e-16 K LysR substrate binding domain
HFOGIIHM_00489 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HFOGIIHM_00490 2.5e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFOGIIHM_00491 1.1e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFOGIIHM_00492 4.6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFOGIIHM_00493 7.9e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFOGIIHM_00494 1.6e-117 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HFOGIIHM_00495 2.9e-237 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HFOGIIHM_00496 1.1e-173 K AI-2E family transporter
HFOGIIHM_00497 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HFOGIIHM_00498 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HFOGIIHM_00499 3.5e-134 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HFOGIIHM_00500 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFOGIIHM_00501 7.8e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFOGIIHM_00502 1.1e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFOGIIHM_00503 6.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HFOGIIHM_00504 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFOGIIHM_00505 4.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFOGIIHM_00506 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFOGIIHM_00507 2.8e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFOGIIHM_00508 6.6e-198 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HFOGIIHM_00509 1.6e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFOGIIHM_00510 4.9e-298 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HFOGIIHM_00511 1.2e-246 purD 6.3.4.13 F Belongs to the GARS family
HFOGIIHM_00512 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFOGIIHM_00513 3.2e-176
HFOGIIHM_00514 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFOGIIHM_00515 5.3e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
HFOGIIHM_00516 1.7e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFOGIIHM_00517 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFOGIIHM_00518 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HFOGIIHM_00519 2.7e-174 malR K Transcriptional regulator, LacI family
HFOGIIHM_00520 4.7e-216 phbA 2.3.1.9 I Belongs to the thiolase family
HFOGIIHM_00521 4.8e-16 malT G Major Facilitator
HFOGIIHM_00522 2.7e-202 malT G Major Facilitator
HFOGIIHM_00523 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HFOGIIHM_00524 4.2e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HFOGIIHM_00525 3.3e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HFOGIIHM_00526 5e-136 puuD S peptidase C26
HFOGIIHM_00527 5.9e-168 yvgN C Aldo keto reductase
HFOGIIHM_00528 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
HFOGIIHM_00529 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HFOGIIHM_00530 3.9e-87 hmpT S ECF-type riboflavin transporter, S component
HFOGIIHM_00531 4.2e-261 nox C NADH oxidase
HFOGIIHM_00532 8.1e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFOGIIHM_00533 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFOGIIHM_00534 1.9e-85
HFOGIIHM_00535 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFOGIIHM_00537 9e-113 K Transcriptional regulator, TetR family
HFOGIIHM_00538 2.2e-72
HFOGIIHM_00539 1.1e-273 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HFOGIIHM_00540 2.7e-277 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HFOGIIHM_00541 0.0 M domain protein
HFOGIIHM_00542 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HFOGIIHM_00543 2.3e-267 G Major Facilitator
HFOGIIHM_00544 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFOGIIHM_00545 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFOGIIHM_00546 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HFOGIIHM_00547 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HFOGIIHM_00548 8.9e-147 recO L Involved in DNA repair and RecF pathway recombination
HFOGIIHM_00549 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFOGIIHM_00550 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HFOGIIHM_00551 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFOGIIHM_00552 5.3e-184 phoH T phosphate starvation-inducible protein PhoH
HFOGIIHM_00553 1.7e-176 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFOGIIHM_00554 1.5e-90 bioY S BioY family
HFOGIIHM_00555 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
HFOGIIHM_00556 1.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFOGIIHM_00557 1.5e-183 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFOGIIHM_00558 7.3e-69 yqeY S YqeY-like protein
HFOGIIHM_00559 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HFOGIIHM_00560 1.1e-265 glnPH2 P ABC transporter permease
HFOGIIHM_00561 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFOGIIHM_00562 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFOGIIHM_00563 1.2e-165 yniA G Phosphotransferase enzyme family
HFOGIIHM_00564 5.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFOGIIHM_00565 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFOGIIHM_00566 9.3e-53
HFOGIIHM_00567 2.5e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFOGIIHM_00568 3.6e-182 prmA J Ribosomal protein L11 methyltransferase
HFOGIIHM_00569 7.5e-58
HFOGIIHM_00571 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFOGIIHM_00572 1.7e-201 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HFOGIIHM_00573 7.9e-279 pipD E Dipeptidase
HFOGIIHM_00574 9.2e-24 3.4.21.88 K Peptidase S24-like
HFOGIIHM_00575 1.4e-10 3.4.21.88 K Peptidase S24-like
HFOGIIHM_00576 1e-81
HFOGIIHM_00577 1.4e-75
HFOGIIHM_00578 6.4e-13
HFOGIIHM_00579 8.1e-142
HFOGIIHM_00580 7.5e-160 3.6.4.12 L Belongs to the 'phage' integrase family
HFOGIIHM_00581 1e-148 S Hydrolases of the alpha beta superfamily
HFOGIIHM_00584 9.7e-33 L DnaD domain protein
HFOGIIHM_00586 5.2e-27
HFOGIIHM_00587 4.3e-15 S Helix-turn-helix domain
HFOGIIHM_00588 1e-09 K transcriptional
HFOGIIHM_00589 5.6e-57 sip L Belongs to the 'phage' integrase family
HFOGIIHM_00595 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HFOGIIHM_00596 1.3e-276 lysP E amino acid
HFOGIIHM_00597 1.3e-09 2.3.1.128 J Acetyltransferase (GNAT) domain
HFOGIIHM_00598 2.7e-120 lssY 3.6.1.27 I phosphatase
HFOGIIHM_00599 7.2e-83 S Threonine/Serine exporter, ThrE
HFOGIIHM_00600 2.1e-132 thrE S Putative threonine/serine exporter
HFOGIIHM_00601 3.5e-31 cspC K Cold shock protein
HFOGIIHM_00602 4.8e-125 sirR K iron dependent repressor
HFOGIIHM_00603 5.9e-166 czcD P cation diffusion facilitator family transporter
HFOGIIHM_00604 7.7e-118 S membrane
HFOGIIHM_00605 1.3e-109 S VIT family
HFOGIIHM_00606 5.5e-83 usp1 T Belongs to the universal stress protein A family
HFOGIIHM_00607 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFOGIIHM_00608 1.5e-152 glnH ET ABC transporter
HFOGIIHM_00609 2.4e-110 gluC P ABC transporter permease
HFOGIIHM_00610 8e-109 glnP P ABC transporter permease
HFOGIIHM_00611 8.3e-221 S CAAX protease self-immunity
HFOGIIHM_00612 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFOGIIHM_00613 2.9e-57
HFOGIIHM_00614 2.6e-74 merR K MerR HTH family regulatory protein
HFOGIIHM_00615 7.2e-270 lmrB EGP Major facilitator Superfamily
HFOGIIHM_00616 5.8e-124 S Domain of unknown function (DUF4811)
HFOGIIHM_00617 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HFOGIIHM_00619 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFOGIIHM_00620 7.5e-58 ytzB S Small secreted protein
HFOGIIHM_00621 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HFOGIIHM_00622 2.9e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFOGIIHM_00623 1.2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HFOGIIHM_00624 1.4e-119 ybhL S Belongs to the BI1 family
HFOGIIHM_00625 1.8e-119 yoaK S Protein of unknown function (DUF1275)
HFOGIIHM_00626 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFOGIIHM_00627 2e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFOGIIHM_00628 9.3e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFOGIIHM_00629 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFOGIIHM_00630 2.7e-207 dnaB L replication initiation and membrane attachment
HFOGIIHM_00631 1e-173 dnaI L Primosomal protein DnaI
HFOGIIHM_00632 6.3e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFOGIIHM_00633 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HFOGIIHM_00634 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFOGIIHM_00635 2.8e-96 yqeG S HAD phosphatase, family IIIA
HFOGIIHM_00636 5.6e-219 yqeH S Ribosome biogenesis GTPase YqeH
HFOGIIHM_00637 1.9e-47 yhbY J RNA-binding protein
HFOGIIHM_00638 7.9e-125 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFOGIIHM_00639 9.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HFOGIIHM_00640 1.3e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFOGIIHM_00641 1.4e-141 yqeM Q Methyltransferase
HFOGIIHM_00642 2.9e-215 ylbM S Belongs to the UPF0348 family
HFOGIIHM_00643 1.1e-98 yceD S Uncharacterized ACR, COG1399
HFOGIIHM_00644 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HFOGIIHM_00645 1.5e-121 K response regulator
HFOGIIHM_00646 2.4e-278 arlS 2.7.13.3 T Histidine kinase
HFOGIIHM_00647 1.8e-268 yjeM E Amino Acid
HFOGIIHM_00648 7.8e-236 V MatE
HFOGIIHM_00649 9.3e-71 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFOGIIHM_00650 1.5e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFOGIIHM_00651 8.2e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HFOGIIHM_00652 6.3e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFOGIIHM_00653 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFOGIIHM_00654 9.7e-58 yodB K Transcriptional regulator, HxlR family
HFOGIIHM_00655 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFOGIIHM_00656 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFOGIIHM_00657 6.9e-113 rlpA M PFAM NLP P60 protein
HFOGIIHM_00658 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
HFOGIIHM_00659 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFOGIIHM_00660 4e-71 yneR S Belongs to the HesB IscA family
HFOGIIHM_00661 0.0 S membrane
HFOGIIHM_00662 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HFOGIIHM_00663 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HFOGIIHM_00664 1.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFOGIIHM_00665 2.4e-113 gluP 3.4.21.105 S Peptidase, S54 family
HFOGIIHM_00666 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HFOGIIHM_00667 1.5e-183 glk 2.7.1.2 G Glucokinase
HFOGIIHM_00668 9.1e-68 yqhL P Rhodanese-like protein
HFOGIIHM_00669 5.9e-22 S Protein of unknown function (DUF3042)
HFOGIIHM_00670 1e-178 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFOGIIHM_00671 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
HFOGIIHM_00672 4e-297 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFOGIIHM_00673 1.1e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HFOGIIHM_00674 3.9e-12
HFOGIIHM_00675 1.3e-156 P Belongs to the nlpA lipoprotein family
HFOGIIHM_00676 5e-101 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFOGIIHM_00677 1.3e-51 S Iron-sulfur cluster assembly protein
HFOGIIHM_00678 2.7e-152
HFOGIIHM_00679 7.5e-178
HFOGIIHM_00680 6.5e-90 dut S Protein conserved in bacteria
HFOGIIHM_00683 2.6e-112 K Transcriptional regulator
HFOGIIHM_00684 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HFOGIIHM_00685 7.4e-55 ysxB J Cysteine protease Prp
HFOGIIHM_00686 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HFOGIIHM_00687 7.5e-208 L Belongs to the 'phage' integrase family
HFOGIIHM_00688 6.3e-51
HFOGIIHM_00691 6.3e-17
HFOGIIHM_00692 5.6e-68 S Pfam:DUF955
HFOGIIHM_00693 8.8e-30 3.4.21.88 K Helix-turn-helix domain
HFOGIIHM_00696 8.6e-11
HFOGIIHM_00701 4.3e-82 S Phage antirepressor protein KilAC domain
HFOGIIHM_00706 9.7e-12 S Domain of unknown function (DUF1508)
HFOGIIHM_00707 2.1e-13 K Cro/C1-type HTH DNA-binding domain
HFOGIIHM_00711 2.7e-78 recT L RecT family
HFOGIIHM_00712 1e-60 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HFOGIIHM_00713 1.3e-35 L Helix-turn-helix domain
HFOGIIHM_00714 9.2e-57 dnaC 3.4.21.53 L IstB-like ATP binding protein
HFOGIIHM_00716 2.4e-42 S ORF6C domain
HFOGIIHM_00718 1.1e-27
HFOGIIHM_00722 9.6e-21
HFOGIIHM_00725 9.8e-08 arpU S Phage transcriptional regulator, ArpU family
HFOGIIHM_00726 2.2e-122 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
HFOGIIHM_00728 2.9e-113 K Belongs to the N(4) N(6)-methyltransferase family
HFOGIIHM_00731 3.9e-72 S Phage terminase, large subunit
HFOGIIHM_00732 4.9e-19 L NUMOD4 motif
HFOGIIHM_00733 5e-167 S Phage terminase, large subunit
HFOGIIHM_00734 1.3e-299 S Phage portal protein, SPP1 Gp6-like
HFOGIIHM_00735 5.5e-175 S Phage Mu protein F like protein
HFOGIIHM_00736 5.3e-79 S Domain of unknown function (DUF4355)
HFOGIIHM_00737 1.3e-204 gpG
HFOGIIHM_00738 6.6e-60 S Phage gp6-like head-tail connector protein
HFOGIIHM_00739 2.5e-52
HFOGIIHM_00740 1.7e-83
HFOGIIHM_00741 7.9e-70
HFOGIIHM_00742 2.1e-80
HFOGIIHM_00743 1.2e-84 S Phage tail assembly chaperone protein, TAC
HFOGIIHM_00745 5.6e-311 D NLP P60 protein
HFOGIIHM_00746 1.2e-168 S Phage tail protein
HFOGIIHM_00747 0.0 M CHAP domain
HFOGIIHM_00750 5.3e-73 S Domain of unknown function (DUF2479)
HFOGIIHM_00753 3.2e-33
HFOGIIHM_00754 5.9e-74 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HFOGIIHM_00755 2.5e-156 M Glycosyl hydrolases family 25
HFOGIIHM_00756 1.2e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HFOGIIHM_00757 3.2e-203 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFOGIIHM_00758 4.5e-123 J 2'-5' RNA ligase superfamily
HFOGIIHM_00759 2.2e-70 yqhY S Asp23 family, cell envelope-related function
HFOGIIHM_00760 3.6e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFOGIIHM_00761 3.4e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFOGIIHM_00762 2e-202 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFOGIIHM_00763 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFOGIIHM_00764 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFOGIIHM_00765 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HFOGIIHM_00766 1e-78 argR K Regulates arginine biosynthesis genes
HFOGIIHM_00767 2.3e-264 recN L May be involved in recombinational repair of damaged DNA
HFOGIIHM_00768 1.7e-54
HFOGIIHM_00769 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HFOGIIHM_00770 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFOGIIHM_00771 5.1e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFOGIIHM_00772 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFOGIIHM_00773 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFOGIIHM_00774 2e-255 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFOGIIHM_00775 7.6e-132 stp 3.1.3.16 T phosphatase
HFOGIIHM_00776 0.0 KLT serine threonine protein kinase
HFOGIIHM_00777 2.6e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFOGIIHM_00778 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HFOGIIHM_00779 7.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
HFOGIIHM_00780 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HFOGIIHM_00781 4.7e-58 asp S Asp23 family, cell envelope-related function
HFOGIIHM_00782 0.0 yloV S DAK2 domain fusion protein YloV
HFOGIIHM_00783 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFOGIIHM_00784 7.3e-189 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFOGIIHM_00785 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFOGIIHM_00786 7.1e-147 S Uncharacterised protein family (UPF0236)
HFOGIIHM_00787 0.0 M domain protein
HFOGIIHM_00788 5.2e-62 M domain protein
HFOGIIHM_00789 4.5e-26
HFOGIIHM_00790 2.5e-197 ampC V Beta-lactamase
HFOGIIHM_00791 4.1e-239 arcA 3.5.3.6 E Arginine
HFOGIIHM_00792 2.7e-79 argR K Regulates arginine biosynthesis genes
HFOGIIHM_00793 6.8e-262 E Arginine ornithine antiporter
HFOGIIHM_00794 5.9e-226 arcD U Amino acid permease
HFOGIIHM_00795 5.4e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HFOGIIHM_00796 8.9e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HFOGIIHM_00797 6e-108 tdk 2.7.1.21 F thymidine kinase
HFOGIIHM_00798 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFOGIIHM_00799 5.4e-169 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFOGIIHM_00800 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFOGIIHM_00801 9.8e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFOGIIHM_00802 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFOGIIHM_00803 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFOGIIHM_00804 3.3e-195 yibE S overlaps another CDS with the same product name
HFOGIIHM_00805 1.8e-131 yibF S overlaps another CDS with the same product name
HFOGIIHM_00806 8.5e-232 pyrP F Permease
HFOGIIHM_00807 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HFOGIIHM_00808 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFOGIIHM_00809 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFOGIIHM_00810 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFOGIIHM_00811 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFOGIIHM_00812 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFOGIIHM_00813 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFOGIIHM_00814 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HFOGIIHM_00815 4.2e-222 yxjG_1 E methionine synthase, vitamin-B12 independent
HFOGIIHM_00816 4.1e-15 S Protein of unknown function (DUF3278)
HFOGIIHM_00817 3.5e-28 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HFOGIIHM_00819 3.2e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFOGIIHM_00820 3.2e-240 E amino acid
HFOGIIHM_00821 9.2e-258 npp S type I phosphodiesterase nucleotide pyrophosphatase
HFOGIIHM_00822 6.9e-226 yxiO S Vacuole effluxer Atg22 like
HFOGIIHM_00824 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFOGIIHM_00825 5.5e-36
HFOGIIHM_00826 4.3e-289 mntH P H( )-stimulated, divalent metal cation uptake system
HFOGIIHM_00827 1.3e-190 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HFOGIIHM_00828 1.9e-89 ygfC K transcriptional regulator (TetR family)
HFOGIIHM_00829 4e-174 hrtB V ABC transporter permease
HFOGIIHM_00830 3.7e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HFOGIIHM_00831 0.0 yhcA V ABC transporter, ATP-binding protein
HFOGIIHM_00832 3e-37
HFOGIIHM_00833 4.1e-50 czrA K Transcriptional regulator, ArsR family
HFOGIIHM_00834 3.8e-227 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFOGIIHM_00835 1.2e-174 scrR K Transcriptional regulator, LacI family
HFOGIIHM_00836 1e-24
HFOGIIHM_00837 1.8e-102
HFOGIIHM_00838 1.6e-216 yttB EGP Major facilitator Superfamily
HFOGIIHM_00839 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HFOGIIHM_00840 9.1e-89
HFOGIIHM_00841 2.7e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HFOGIIHM_00842 7.7e-44 S Putative peptidoglycan binding domain
HFOGIIHM_00845 4.9e-87
HFOGIIHM_00846 1.9e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
HFOGIIHM_00847 2.7e-274 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFOGIIHM_00848 1e-104 pncA Q Isochorismatase family
HFOGIIHM_00849 1.1e-208 yegU O ADP-ribosylglycohydrolase
HFOGIIHM_00850 1.8e-256 F Belongs to the purine-cytosine permease (2.A.39) family
HFOGIIHM_00851 3e-167 G Belongs to the carbohydrate kinase PfkB family
HFOGIIHM_00852 5.6e-39 hxlR K regulation of RNA biosynthetic process
HFOGIIHM_00853 4.3e-242 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HFOGIIHM_00854 2.6e-132 IQ Dehydrogenase reductase
HFOGIIHM_00855 4.4e-38
HFOGIIHM_00856 5.7e-115 ywnB S NAD(P)H-binding
HFOGIIHM_00857 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
HFOGIIHM_00858 1e-254 nhaC C Na H antiporter NhaC
HFOGIIHM_00859 2e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFOGIIHM_00861 2.1e-102 ydeN S Serine hydrolase
HFOGIIHM_00862 2e-62 psiE S Phosphate-starvation-inducible E
HFOGIIHM_00863 2.9e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFOGIIHM_00865 2.1e-182 S Aldo keto reductase
HFOGIIHM_00866 1.5e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HFOGIIHM_00867 0.0 L Helicase C-terminal domain protein
HFOGIIHM_00869 1.8e-256 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HFOGIIHM_00870 3.3e-55 S Sugar efflux transporter for intercellular exchange
HFOGIIHM_00871 1.7e-128
HFOGIIHM_00872 6.4e-131 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HFOGIIHM_00873 0.0 cadA P P-type ATPase
HFOGIIHM_00874 4.5e-227 5.4.2.7 G Metalloenzyme superfamily
HFOGIIHM_00875 1.5e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HFOGIIHM_00876 2e-22
HFOGIIHM_00877 2e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
HFOGIIHM_00878 4.7e-174 L PFAM plasmid pRiA4b ORF-3 family protein
HFOGIIHM_00879 1.5e-114 L PFAM plasmid pRiA4b ORF-3 family protein
HFOGIIHM_00880 2.7e-207 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HFOGIIHM_00881 7.8e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFOGIIHM_00882 5.5e-161 mleR K LysR family
HFOGIIHM_00883 3.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HFOGIIHM_00884 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFOGIIHM_00885 3.1e-267 frdC 1.3.5.4 C FAD binding domain
HFOGIIHM_00886 5.9e-129 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFOGIIHM_00887 5.5e-171 citP P Sodium:sulfate symporter transmembrane region
HFOGIIHM_00888 6.3e-123 citR K sugar-binding domain protein
HFOGIIHM_00889 1.2e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HFOGIIHM_00890 2.2e-148 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HFOGIIHM_00891 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
HFOGIIHM_00892 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HFOGIIHM_00893 2.1e-272 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HFOGIIHM_00894 5e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HFOGIIHM_00895 7.2e-112 ydjP I Alpha/beta hydrolase family
HFOGIIHM_00896 1e-159 mleR K LysR family
HFOGIIHM_00897 9.4e-253 yjjP S Putative threonine/serine exporter
HFOGIIHM_00898 7.2e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
HFOGIIHM_00899 4.8e-266 emrY EGP Major facilitator Superfamily
HFOGIIHM_00900 2.6e-188 I Alpha beta
HFOGIIHM_00901 1.6e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HFOGIIHM_00902 1.7e-88
HFOGIIHM_00903 4.2e-294 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HFOGIIHM_00904 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFOGIIHM_00905 3.6e-171 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFOGIIHM_00906 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFOGIIHM_00907 2.9e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFOGIIHM_00908 1.6e-268 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFOGIIHM_00909 9.8e-67 yabR J RNA binding
HFOGIIHM_00910 2.3e-57 divIC D Septum formation initiator
HFOGIIHM_00911 1.6e-39 yabO J S4 domain protein
HFOGIIHM_00912 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFOGIIHM_00913 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFOGIIHM_00914 3.6e-114 S (CBS) domain
HFOGIIHM_00915 3.1e-147 tesE Q hydratase
HFOGIIHM_00916 2.1e-243 codA 3.5.4.1 F cytosine deaminase
HFOGIIHM_00917 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HFOGIIHM_00918 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
HFOGIIHM_00919 7.9e-213 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFOGIIHM_00920 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFOGIIHM_00922 2.6e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFOGIIHM_00923 1e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HFOGIIHM_00924 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFOGIIHM_00925 3.4e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFOGIIHM_00926 2.4e-276 A chlorophyll binding
HFOGIIHM_00927 1.1e-181 S YSIRK type signal peptide
HFOGIIHM_00928 2.8e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFOGIIHM_00929 8.4e-221 ecsB U ABC transporter
HFOGIIHM_00930 1.2e-137 ecsA V ABC transporter, ATP-binding protein
HFOGIIHM_00931 8.3e-78 hit FG histidine triad
HFOGIIHM_00933 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFOGIIHM_00934 0.0 L AAA domain
HFOGIIHM_00935 1.3e-229 yhaO L Ser Thr phosphatase family protein
HFOGIIHM_00936 2.6e-40 yheA S Belongs to the UPF0342 family
HFOGIIHM_00937 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HFOGIIHM_00938 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HFOGIIHM_00939 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFOGIIHM_00940 8.4e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFOGIIHM_00942 3.3e-40
HFOGIIHM_00943 1e-43
HFOGIIHM_00944 1.2e-216 folP 2.5.1.15 H dihydropteroate synthase
HFOGIIHM_00945 2.6e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HFOGIIHM_00946 6.7e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HFOGIIHM_00947 2.4e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HFOGIIHM_00948 1.2e-94 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HFOGIIHM_00949 1.1e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFOGIIHM_00950 8.7e-74
HFOGIIHM_00951 7.6e-31 L PFAM transposase IS200-family protein
HFOGIIHM_00952 4.5e-143 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFOGIIHM_00953 3.4e-138 cdsA 2.7.7.41 I Belongs to the CDS family
HFOGIIHM_00954 9.8e-236 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HFOGIIHM_00955 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFOGIIHM_00956 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFOGIIHM_00957 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
HFOGIIHM_00958 1.2e-216 nusA K Participates in both transcription termination and antitermination
HFOGIIHM_00959 1e-44 ylxR K Protein of unknown function (DUF448)
HFOGIIHM_00960 4.5e-49 ylxQ J ribosomal protein
HFOGIIHM_00961 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFOGIIHM_00962 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFOGIIHM_00963 1.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFOGIIHM_00964 1.9e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HFOGIIHM_00965 2e-64
HFOGIIHM_00966 2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFOGIIHM_00967 1.2e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFOGIIHM_00968 0.0 dnaK O Heat shock 70 kDa protein
HFOGIIHM_00969 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFOGIIHM_00970 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFOGIIHM_00971 7.7e-160 endA V DNA/RNA non-specific endonuclease
HFOGIIHM_00972 1e-254 yifK E Amino acid permease
HFOGIIHM_00974 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFOGIIHM_00975 1.3e-232 N Uncharacterized conserved protein (DUF2075)
HFOGIIHM_00976 6.1e-123 S SNARE associated Golgi protein
HFOGIIHM_00977 0.0 uvrA3 L excinuclease ABC, A subunit
HFOGIIHM_00978 2.9e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFOGIIHM_00979 4.9e-58 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFOGIIHM_00980 4.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFOGIIHM_00981 1.3e-143 S DUF218 domain
HFOGIIHM_00982 0.0 ubiB S ABC1 family
HFOGIIHM_00983 8.5e-246 yhdP S Transporter associated domain
HFOGIIHM_00984 5e-75 copY K Copper transport repressor CopY TcrY
HFOGIIHM_00985 6.9e-243 EGP Major facilitator Superfamily
HFOGIIHM_00986 1.7e-73 yeaL S UPF0756 membrane protein
HFOGIIHM_00987 8.8e-77 yphH S Cupin domain
HFOGIIHM_00988 1.5e-80 C Flavodoxin
HFOGIIHM_00989 8e-140 K LysR substrate binding domain protein
HFOGIIHM_00990 1.1e-161 1.1.1.346 C Aldo keto reductase
HFOGIIHM_00991 2.1e-39 gcvR T Belongs to the UPF0237 family
HFOGIIHM_00992 6e-244 XK27_08635 S UPF0210 protein
HFOGIIHM_00993 1.2e-96 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFOGIIHM_00994 4.7e-74 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFOGIIHM_00995 5.9e-120 L PFAM Integrase catalytic region
HFOGIIHM_00996 8.5e-174 fecB P Periplasmic binding protein
HFOGIIHM_00997 6.3e-137 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HFOGIIHM_00998 1.8e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFOGIIHM_00999 3.6e-76 S Flavodoxin
HFOGIIHM_01000 3.7e-64 moaE 2.8.1.12 H MoaE protein
HFOGIIHM_01001 4.9e-35 moaD 2.8.1.12 H ThiS family
HFOGIIHM_01002 3.9e-218 narK P Transporter, major facilitator family protein
HFOGIIHM_01003 1.7e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HFOGIIHM_01004 1.4e-181
HFOGIIHM_01005 1.6e-18
HFOGIIHM_01006 2.6e-115 nreC K PFAM regulatory protein LuxR
HFOGIIHM_01007 5.1e-190 comP 2.7.13.3 F Sensor histidine kinase
HFOGIIHM_01008 3e-44
HFOGIIHM_01009 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HFOGIIHM_01010 3e-84 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HFOGIIHM_01011 3.2e-228 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HFOGIIHM_01012 3.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HFOGIIHM_01013 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HFOGIIHM_01014 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFOGIIHM_01015 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HFOGIIHM_01016 7.9e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HFOGIIHM_01017 9.6e-129 narI 1.7.5.1 C Nitrate reductase
HFOGIIHM_01018 8.9e-77 S PAS domain
HFOGIIHM_01019 9.3e-103 dnaQ 2.7.7.7 L DNA polymerase III
HFOGIIHM_01020 7.3e-169 murB 1.3.1.98 M Cell wall formation
HFOGIIHM_01021 4.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFOGIIHM_01022 6e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFOGIIHM_01023 3.7e-249 fucP G Major Facilitator Superfamily
HFOGIIHM_01024 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFOGIIHM_01025 1.2e-126 ybbR S YbbR-like protein
HFOGIIHM_01026 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFOGIIHM_01027 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFOGIIHM_01028 8.7e-53
HFOGIIHM_01029 0.0 oatA I Acyltransferase
HFOGIIHM_01030 2.1e-79 K Transcriptional regulator
HFOGIIHM_01031 8.9e-150 XK27_02985 S Cof-like hydrolase
HFOGIIHM_01032 1.8e-78 lytE M Lysin motif
HFOGIIHM_01034 3.8e-136 K response regulator
HFOGIIHM_01035 8.1e-274 yclK 2.7.13.3 T Histidine kinase
HFOGIIHM_01036 5.7e-155 glcU U sugar transport
HFOGIIHM_01037 1.4e-102 lacA 2.3.1.79 S Transferase hexapeptide repeat
HFOGIIHM_01038 5.3e-264 pgi 5.3.1.9 G Belongs to the GPI family
HFOGIIHM_01039 2.1e-26
HFOGIIHM_01041 5.6e-32 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HFOGIIHM_01042 1e-110 K Bacterial regulatory proteins, tetR family
HFOGIIHM_01043 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFOGIIHM_01044 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFOGIIHM_01045 1.5e-201 ykiI
HFOGIIHM_01046 2.7e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HFOGIIHM_01047 5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFOGIIHM_01048 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFOGIIHM_01049 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFOGIIHM_01050 1.3e-198 L Transposase
HFOGIIHM_01051 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HFOGIIHM_01052 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFOGIIHM_01053 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HFOGIIHM_01054 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFOGIIHM_01055 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFOGIIHM_01056 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFOGIIHM_01057 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFOGIIHM_01058 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFOGIIHM_01059 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFOGIIHM_01060 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HFOGIIHM_01061 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFOGIIHM_01062 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFOGIIHM_01063 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFOGIIHM_01064 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFOGIIHM_01065 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFOGIIHM_01066 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFOGIIHM_01067 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFOGIIHM_01068 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFOGIIHM_01069 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFOGIIHM_01070 2.9e-24 rpmD J Ribosomal protein L30
HFOGIIHM_01071 6.8e-64 rplO J Binds to the 23S rRNA
HFOGIIHM_01072 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFOGIIHM_01073 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFOGIIHM_01074 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFOGIIHM_01075 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HFOGIIHM_01076 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFOGIIHM_01077 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFOGIIHM_01078 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFOGIIHM_01079 1.1e-62 rplQ J Ribosomal protein L17
HFOGIIHM_01080 1.9e-147 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFOGIIHM_01081 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFOGIIHM_01082 1.3e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFOGIIHM_01083 3.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFOGIIHM_01084 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFOGIIHM_01085 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HFOGIIHM_01086 9.4e-141 IQ reductase
HFOGIIHM_01087 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
HFOGIIHM_01088 4.6e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFOGIIHM_01089 9.4e-214 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFOGIIHM_01090 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HFOGIIHM_01091 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFOGIIHM_01092 2.1e-202 camS S sex pheromone
HFOGIIHM_01093 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFOGIIHM_01094 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFOGIIHM_01095 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFOGIIHM_01096 3e-187 yegS 2.7.1.107 G Lipid kinase
HFOGIIHM_01097 2e-12
HFOGIIHM_01098 3e-34 doc S Fic/DOC family
HFOGIIHM_01099 1.9e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFOGIIHM_01100 1.5e-47 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HFOGIIHM_01101 0.0 L Helicase C-terminal domain protein
HFOGIIHM_01102 1.6e-25
HFOGIIHM_01104 1.1e-170 L Plasmid pRiA4b ORF-3-like protein
HFOGIIHM_01106 6.3e-61 S Protein of unknown function (DUF3021)
HFOGIIHM_01107 6.4e-73 K LytTr DNA-binding domain
HFOGIIHM_01108 3.1e-145 cylB V ABC-2 type transporter
HFOGIIHM_01109 2.3e-156 cylA V ABC transporter
HFOGIIHM_01110 1.7e-43
HFOGIIHM_01111 2.1e-95 L PFAM Integrase catalytic region
HFOGIIHM_01112 4.4e-56 L PFAM Integrase catalytic region
HFOGIIHM_01113 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HFOGIIHM_01114 7.9e-35 copZ C Heavy-metal-associated domain
HFOGIIHM_01115 2.7e-94 dps P Belongs to the Dps family
HFOGIIHM_01116 2.6e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HFOGIIHM_01117 7.1e-16 ung2 3.2.2.27 L Uracil-DNA glycosylase
HFOGIIHM_01118 9.8e-15 L Helix-turn-helix domain
HFOGIIHM_01120 4e-207 amtB P ammonium transporter
HFOGIIHM_01121 2.2e-254 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HFOGIIHM_01122 1e-84 yvbK 3.1.3.25 K GNAT family
HFOGIIHM_01123 2.5e-92
HFOGIIHM_01124 1.4e-124 pnb C nitroreductase
HFOGIIHM_01125 6.3e-84 ogt 2.1.1.63 L Methyltransferase
HFOGIIHM_01126 9.8e-129 L transposase, IS605 OrfB family
HFOGIIHM_01127 4.2e-77 XK27_00915 C Luciferase-like monooxygenase
HFOGIIHM_01128 5.6e-156 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HFOGIIHM_01129 5.6e-69 S Protein of unknown function (DUF3021)
HFOGIIHM_01130 2.9e-78 K LytTr DNA-binding domain
HFOGIIHM_01131 2.5e-97 K Acetyltransferase (GNAT) family
HFOGIIHM_01132 3.7e-22
HFOGIIHM_01133 2.9e-120 ybhL S Belongs to the BI1 family
HFOGIIHM_01134 5.8e-82 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HFOGIIHM_01135 6.3e-201 S Protein of unknown function (DUF3114)
HFOGIIHM_01136 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HFOGIIHM_01137 2.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HFOGIIHM_01138 1.3e-110 yvdD 3.2.2.10 S Belongs to the LOG family
HFOGIIHM_01139 7e-62 S Domain of unknown function (DUF4828)
HFOGIIHM_01140 4.5e-191 mocA S Oxidoreductase
HFOGIIHM_01141 3.6e-233 yfmL 3.6.4.13 L DEAD DEAH box helicase
HFOGIIHM_01143 3.3e-211 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFOGIIHM_01144 3.6e-54
HFOGIIHM_01145 1.5e-74 gtcA S Teichoic acid glycosylation protein
HFOGIIHM_01146 2.1e-79 fld C Flavodoxin
HFOGIIHM_01147 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
HFOGIIHM_01148 8.4e-223 arcT 2.6.1.1 E Aminotransferase
HFOGIIHM_01149 1.7e-257 E Arginine ornithine antiporter
HFOGIIHM_01150 1.1e-281 yjeM E Amino Acid
HFOGIIHM_01151 8.5e-154 yihY S Belongs to the UPF0761 family
HFOGIIHM_01152 5e-34 S Protein of unknown function (DUF2922)
HFOGIIHM_01153 2.2e-31
HFOGIIHM_01154 9.3e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
HFOGIIHM_01155 3.2e-149 cps1D M Domain of unknown function (DUF4422)
HFOGIIHM_01156 9.8e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HFOGIIHM_01157 1.7e-122 rfbP 2.7.8.6 M Bacterial sugar transferase
HFOGIIHM_01158 6e-221 glf 5.4.99.9 M UDP-galactopyranose mutase
HFOGIIHM_01159 4.3e-217 cps3F
HFOGIIHM_01160 1.4e-105 M biosynthesis protein
HFOGIIHM_01161 4.9e-260 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HFOGIIHM_01162 9.3e-200 waaB GT4 M Glycosyl transferases group 1
HFOGIIHM_01163 9.6e-194 M transferase activity, transferring glycosyl groups
HFOGIIHM_01164 1.7e-196 S enterobacterial common antigen metabolic process
HFOGIIHM_01165 1.6e-141 acmD M repeat protein
HFOGIIHM_01166 1e-23
HFOGIIHM_01167 2.6e-103 V VanZ like family
HFOGIIHM_01168 2.2e-233 cycA E Amino acid permease
HFOGIIHM_01169 4.3e-85 perR P Belongs to the Fur family
HFOGIIHM_01170 4.2e-259 EGP Major facilitator Superfamily
HFOGIIHM_01171 1.5e-29
HFOGIIHM_01172 2.5e-100 tag 3.2.2.20 L glycosylase
HFOGIIHM_01173 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFOGIIHM_01174 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFOGIIHM_01175 4.5e-42
HFOGIIHM_01176 6.4e-304 ytgP S Polysaccharide biosynthesis protein
HFOGIIHM_01177 1.2e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFOGIIHM_01178 8.7e-278 pepV 3.5.1.18 E dipeptidase PepV
HFOGIIHM_01179 1.9e-86 uspA T Belongs to the universal stress protein A family
HFOGIIHM_01180 2.5e-50 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFOGIIHM_01181 1.6e-111 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFOGIIHM_01182 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
HFOGIIHM_01183 5.9e-114
HFOGIIHM_01184 4.6e-188 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HFOGIIHM_01185 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFOGIIHM_01186 2.1e-32
HFOGIIHM_01187 2.8e-120 S CAAX protease self-immunity
HFOGIIHM_01188 1.9e-43
HFOGIIHM_01190 1e-198 V Beta-lactamase
HFOGIIHM_01191 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFOGIIHM_01192 1.7e-122 yhiD S MgtC family
HFOGIIHM_01193 4e-121 S GyrI-like small molecule binding domain
HFOGIIHM_01195 1.8e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HFOGIIHM_01196 3.2e-50 azlD E Branched-chain amino acid transport
HFOGIIHM_01197 2e-121 azlC E azaleucine resistance protein AzlC
HFOGIIHM_01198 2.6e-266 K Aminotransferase class I and II
HFOGIIHM_01199 1.6e-304 S amidohydrolase
HFOGIIHM_01200 1.6e-165 S reductase
HFOGIIHM_01201 1.6e-93 2.3.1.183 M Acetyltransferase GNAT family
HFOGIIHM_01202 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HFOGIIHM_01203 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
HFOGIIHM_01204 4.8e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFOGIIHM_01205 0.0 asnB 6.3.5.4 E Asparagine synthase
HFOGIIHM_01206 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFOGIIHM_01207 1.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFOGIIHM_01208 1.6e-41 S Cytochrome B5
HFOGIIHM_01209 5.4e-09 S Cytochrome B5
HFOGIIHM_01210 1.8e-39 S Cytochrome B5
HFOGIIHM_01211 2.4e-77 elaA S Gnat family
HFOGIIHM_01212 1.4e-121 GM NmrA-like family
HFOGIIHM_01213 2.5e-52 hxlR K Transcriptional regulator, HxlR family
HFOGIIHM_01214 1.1e-109 XK27_02070 S Nitroreductase family
HFOGIIHM_01215 6.2e-84 K Transcriptional regulator, HxlR family
HFOGIIHM_01216 5.5e-242
HFOGIIHM_01217 2e-211 EGP Major facilitator Superfamily
HFOGIIHM_01218 4.7e-257 pepC 3.4.22.40 E aminopeptidase
HFOGIIHM_01219 3.7e-114 ylbE GM NAD dependent epimerase dehydratase family protein
HFOGIIHM_01220 0.0 pepN 3.4.11.2 E aminopeptidase
HFOGIIHM_01221 6.3e-94 folT S ECF transporter, substrate-specific component
HFOGIIHM_01222 1.7e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
HFOGIIHM_01223 6e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HFOGIIHM_01224 3.8e-78 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HFOGIIHM_01225 1.8e-33 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HFOGIIHM_01226 2.1e-205 2.7.7.65 T GGDEF domain
HFOGIIHM_01227 7.5e-91
HFOGIIHM_01228 4e-256 pgaC GT2 M Glycosyl transferase
HFOGIIHM_01229 1.7e-159 T EAL domain
HFOGIIHM_01230 6.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HFOGIIHM_01231 1.8e-148 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HFOGIIHM_01232 5.2e-262 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFOGIIHM_01233 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
HFOGIIHM_01234 3.7e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HFOGIIHM_01235 8.8e-286 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HFOGIIHM_01236 2e-100 maa 2.3.1.79 S Maltose O-acetyltransferase
HFOGIIHM_01237 2.2e-159 ytbE 1.1.1.346 S Aldo keto reductase
HFOGIIHM_01238 1.5e-208 araR K Transcriptional regulator
HFOGIIHM_01239 4.3e-83 usp6 T universal stress protein
HFOGIIHM_01240 4.4e-46
HFOGIIHM_01241 3.4e-244 rarA L recombination factor protein RarA
HFOGIIHM_01242 1.7e-87 yueI S Protein of unknown function (DUF1694)
HFOGIIHM_01243 1e-20
HFOGIIHM_01244 8.1e-75 4.4.1.5 E Glyoxalase
HFOGIIHM_01245 2.5e-138 S Membrane
HFOGIIHM_01246 1.1e-141 S Belongs to the UPF0246 family
HFOGIIHM_01247 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HFOGIIHM_01248 6.7e-164 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFOGIIHM_01249 3.7e-235 L Transposase
HFOGIIHM_01250 2.4e-221 V domain protein
HFOGIIHM_01251 6e-94 K Transcriptional regulator (TetR family)
HFOGIIHM_01252 4.9e-38 pspC KT positive regulation of macromolecule biosynthetic process
HFOGIIHM_01253 5.8e-152
HFOGIIHM_01254 3.1e-17 3.2.1.14 GH18
HFOGIIHM_01255 1.5e-82 zur P Belongs to the Fur family
HFOGIIHM_01256 1.4e-101 gmk2 2.7.4.8 F Guanylate kinase
HFOGIIHM_01257 2.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HFOGIIHM_01258 3e-254 yfnA E Amino Acid
HFOGIIHM_01259 2.4e-229
HFOGIIHM_01260 3.6e-207 potD P ABC transporter
HFOGIIHM_01261 6.5e-140 potC P ABC transporter permease
HFOGIIHM_01262 4.5e-146 potB P ABC transporter permease
HFOGIIHM_01263 5.9e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFOGIIHM_01264 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFOGIIHM_01265 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HFOGIIHM_01266 5.9e-17 2.3.1.128 K Acetyltransferase (GNAT) domain
HFOGIIHM_01267 9.9e-46 2.3.1.128 K Acetyltransferase (GNAT) domain
HFOGIIHM_01268 7.2e-232 lmrB EGP Major facilitator Superfamily
HFOGIIHM_01269 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HFOGIIHM_01270 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFOGIIHM_01271 8.3e-149 sufD O Uncharacterized protein family (UPF0051)
HFOGIIHM_01272 5.7e-72 lytE M LysM domain protein
HFOGIIHM_01273 0.0 oppD EP Psort location Cytoplasmic, score
HFOGIIHM_01274 2.3e-93 lytE M LysM domain protein
HFOGIIHM_01275 1.2e-148 xth 3.1.11.2 L exodeoxyribonuclease III
HFOGIIHM_01276 7.3e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HFOGIIHM_01277 1.2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
HFOGIIHM_01278 1e-156 yeaE S Aldo keto
HFOGIIHM_01279 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HFOGIIHM_01280 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HFOGIIHM_01281 1.5e-79 S Psort location Cytoplasmic, score
HFOGIIHM_01282 2.2e-85 S Short repeat of unknown function (DUF308)
HFOGIIHM_01283 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
HFOGIIHM_01284 1.3e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFOGIIHM_01285 1.3e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
HFOGIIHM_01286 1.2e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HFOGIIHM_01287 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFOGIIHM_01288 2.7e-39 ptsH G phosphocarrier protein HPR
HFOGIIHM_01289 2.9e-27
HFOGIIHM_01290 0.0 clpE O Belongs to the ClpA ClpB family
HFOGIIHM_01291 1.7e-100 S Pfam:DUF3816
HFOGIIHM_01292 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HFOGIIHM_01293 5.1e-114
HFOGIIHM_01294 2.3e-156 V ABC transporter, ATP-binding protein
HFOGIIHM_01295 1.2e-64 gntR1 K Transcriptional regulator, GntR family
HFOGIIHM_01296 2.1e-171 3.2.1.23, 3.2.1.89 G arabinogalactan endo-1,4-beta-galactosidase activity
HFOGIIHM_01297 6.6e-281 ganB 3.2.1.89 G arabinogalactan
HFOGIIHM_01298 6.7e-40 S dextransucrase activity
HFOGIIHM_01299 3.6e-45 L PFAM Integrase catalytic region
HFOGIIHM_01300 7.1e-63
HFOGIIHM_01301 5.2e-14
HFOGIIHM_01302 5.8e-121
HFOGIIHM_01303 7.2e-137 V ABC transporter
HFOGIIHM_01304 2.4e-212 EGP Major facilitator Superfamily
HFOGIIHM_01305 5.5e-256 G PTS system Galactitol-specific IIC component
HFOGIIHM_01306 9.1e-181 1.6.5.5 C Zinc-binding dehydrogenase
HFOGIIHM_01307 9.7e-163
HFOGIIHM_01308 1e-72 K Transcriptional regulator
HFOGIIHM_01309 1.5e-188 D Alpha beta
HFOGIIHM_01310 3.2e-51 ypaA S Protein of unknown function (DUF1304)
HFOGIIHM_01311 0.0 yjcE P Sodium proton antiporter
HFOGIIHM_01312 1.6e-52 yvlA
HFOGIIHM_01313 1.7e-114 P Cobalt transport protein
HFOGIIHM_01314 1.7e-249 cbiO1 S ABC transporter, ATP-binding protein
HFOGIIHM_01315 5.1e-96 S ABC-type cobalt transport system, permease component
HFOGIIHM_01316 3.3e-133 S membrane transporter protein
HFOGIIHM_01317 4.3e-13
HFOGIIHM_01318 1.8e-75 S Domain of unknown function (DUF4767)
HFOGIIHM_01319 5.1e-198 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HFOGIIHM_01320 1.9e-115 S Membrane
HFOGIIHM_01321 2.7e-94 O Zinc-dependent metalloprotease
HFOGIIHM_01322 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFOGIIHM_01323 9.5e-158 metQ_4 P Belongs to the nlpA lipoprotein family
HFOGIIHM_01325 1.4e-182 S Phosphotransferase system, EIIC
HFOGIIHM_01326 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFOGIIHM_01327 2.1e-167
HFOGIIHM_01328 6.9e-40 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFOGIIHM_01329 1.6e-205 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HFOGIIHM_01330 1.3e-162 K LysR substrate binding domain
HFOGIIHM_01331 1.4e-141 manA 5.3.1.8 G mannose-6-phosphate isomerase
HFOGIIHM_01332 4.4e-97 2.3.1.128 K acetyltransferase
HFOGIIHM_01333 6.2e-185
HFOGIIHM_01334 1.1e-17 K Transcriptional regulator, HxlR family
HFOGIIHM_01335 1.4e-95 K Acetyltransferase (GNAT) domain
HFOGIIHM_01336 1.2e-160 S Alpha beta hydrolase
HFOGIIHM_01337 3.1e-161 gspA M family 8
HFOGIIHM_01338 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFOGIIHM_01339 9.4e-94
HFOGIIHM_01340 1.7e-162 degV S EDD domain protein, DegV family
HFOGIIHM_01341 0.0 FbpA K Fibronectin-binding protein
HFOGIIHM_01342 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HFOGIIHM_01343 4.3e-208 carA 6.3.5.5 F Belongs to the CarA family
HFOGIIHM_01344 4.8e-176 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFOGIIHM_01345 1.3e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFOGIIHM_01346 1.5e-65 esbA S Family of unknown function (DUF5322)
HFOGIIHM_01347 6.9e-71 rnhA 3.1.26.4 L Ribonuclease HI
HFOGIIHM_01348 1.2e-232 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HFOGIIHM_01349 2.5e-60 F Belongs to the NrdI family
HFOGIIHM_01350 1.4e-124 yciB M ErfK YbiS YcfS YnhG
HFOGIIHM_01352 8.3e-48
HFOGIIHM_01353 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HFOGIIHM_01354 3.6e-125 S Alpha beta hydrolase
HFOGIIHM_01355 2.2e-207 gldA 1.1.1.6 C dehydrogenase
HFOGIIHM_01356 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFOGIIHM_01357 1.3e-41
HFOGIIHM_01358 4e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
HFOGIIHM_01359 2.1e-285 S C4-dicarboxylate anaerobic carrier
HFOGIIHM_01360 7.2e-267 aaxC E Arginine ornithine antiporter
HFOGIIHM_01361 3.5e-182 4.1.1.22 H Histidine carboxylase PI chain
HFOGIIHM_01362 2.2e-93 S Family of unknown function (DUF5449)
HFOGIIHM_01363 2.2e-208 hisS 6.1.1.21 J histidyl-tRNA synthetase
HFOGIIHM_01364 1.6e-244 nhaC C Na H antiporter NhaC
HFOGIIHM_01365 7.3e-242 pbuX F xanthine permease
HFOGIIHM_01366 2.7e-282 pipD E Dipeptidase
HFOGIIHM_01367 9.7e-169 corA P CorA-like Mg2+ transporter protein
HFOGIIHM_01368 2e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFOGIIHM_01369 2.3e-131 terC P membrane
HFOGIIHM_01370 7.2e-55 trxA O Belongs to the thioredoxin family
HFOGIIHM_01371 6.4e-238 mepA V MATE efflux family protein
HFOGIIHM_01372 5.2e-56 K Transcriptional regulator, ArsR family
HFOGIIHM_01373 5.1e-96 P Cadmium resistance transporter
HFOGIIHM_01374 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
HFOGIIHM_01375 8.6e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HFOGIIHM_01376 2.9e-182 ABC-SBP S ABC transporter
HFOGIIHM_01377 2.2e-73 M PFAM NLP P60 protein
HFOGIIHM_01378 7.8e-14 relB L RelB antitoxin
HFOGIIHM_01379 1e-108 S Protein of unknown function (DUF3278)
HFOGIIHM_01381 2.9e-11
HFOGIIHM_01382 4.4e-275 S ABC transporter, ATP-binding protein
HFOGIIHM_01383 1.8e-147 S Putative ABC-transporter type IV
HFOGIIHM_01384 1.5e-106 NU mannosyl-glycoprotein
HFOGIIHM_01385 4.9e-249 brnQ U Component of the transport system for branched-chain amino acids
HFOGIIHM_01386 4.9e-232 S Uncharacterized protein conserved in bacteria (DUF2325)
HFOGIIHM_01387 1.4e-206 nrnB S DHHA1 domain
HFOGIIHM_01388 1.1e-49
HFOGIIHM_01389 2.4e-141 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFOGIIHM_01390 3.3e-18 S Domain of unknown function (DUF4767)
HFOGIIHM_01391 1.6e-54
HFOGIIHM_01392 6e-123 yrkL S Flavodoxin-like fold
HFOGIIHM_01394 1.4e-65 yeaO S Protein of unknown function, DUF488
HFOGIIHM_01395 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HFOGIIHM_01396 1.4e-209 3.1.3.1 S associated with various cellular activities
HFOGIIHM_01397 5.6e-247 S Putative metallopeptidase domain
HFOGIIHM_01398 3.6e-48
HFOGIIHM_01399 0.0 pepO 3.4.24.71 O Peptidase family M13
HFOGIIHM_01400 3.9e-113 K Helix-turn-helix XRE-family like proteins
HFOGIIHM_01401 3.4e-91 ymdB S Macro domain protein
HFOGIIHM_01402 3.9e-199 EGP Major facilitator Superfamily
HFOGIIHM_01403 8.4e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFOGIIHM_01404 8.8e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HFOGIIHM_01405 7.4e-160 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HFOGIIHM_01406 1.1e-141 L PFAM Integrase catalytic region
HFOGIIHM_01407 0.0 ysaB V FtsX-like permease family
HFOGIIHM_01408 3.4e-135 macB2 V ABC transporter, ATP-binding protein
HFOGIIHM_01409 8.7e-184 T Histidine kinase-like ATPases
HFOGIIHM_01410 7.5e-126 K response regulator
HFOGIIHM_01411 2.9e-159 ytbE 1.1.1.346 S Aldo keto reductase
HFOGIIHM_01412 1.8e-136 pnuC H nicotinamide mononucleotide transporter
HFOGIIHM_01413 1.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFOGIIHM_01414 4.6e-205
HFOGIIHM_01415 9.1e-53
HFOGIIHM_01416 9.1e-36
HFOGIIHM_01417 4.3e-94 yxkA S Phosphatidylethanolamine-binding protein
HFOGIIHM_01418 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HFOGIIHM_01419 2.2e-187 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HFOGIIHM_01420 1.2e-227 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFOGIIHM_01421 1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HFOGIIHM_01422 9.1e-181 galR K Transcriptional regulator
HFOGIIHM_01423 1.7e-97 dedA 3.1.3.1 S SNARE associated Golgi protein
HFOGIIHM_01424 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFOGIIHM_01425 1.8e-78 K AsnC family
HFOGIIHM_01426 1.6e-79 uspA T universal stress protein
HFOGIIHM_01427 2e-36 ltrA S Bacterial low temperature requirement A protein (LtrA)
HFOGIIHM_01428 3.2e-80 ltrA S Bacterial low temperature requirement A protein (LtrA)
HFOGIIHM_01429 0.0 lacS G Transporter
HFOGIIHM_01430 1.9e-40
HFOGIIHM_01431 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFOGIIHM_01432 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFOGIIHM_01433 3.1e-193 yeaN P Transporter, major facilitator family protein
HFOGIIHM_01434 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
HFOGIIHM_01435 2.2e-84 nrdI F Belongs to the NrdI family
HFOGIIHM_01436 2.8e-241 yhdP S Transporter associated domain
HFOGIIHM_01437 2.8e-154 ypdB V (ABC) transporter
HFOGIIHM_01438 5.7e-89 GM epimerase
HFOGIIHM_01439 6.1e-91 M1-874 K Domain of unknown function (DUF1836)
HFOGIIHM_01440 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
HFOGIIHM_01441 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
HFOGIIHM_01442 7.9e-173 S AI-2E family transporter
HFOGIIHM_01443 2e-160 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HFOGIIHM_01444 5.6e-161
HFOGIIHM_01445 2.7e-41 L PFAM Integrase catalytic region
HFOGIIHM_01446 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HFOGIIHM_01447 1.5e-147 eutJ E Hsp70 protein
HFOGIIHM_01448 4.8e-221 patA 2.6.1.1 E Aminotransferase
HFOGIIHM_01449 3.8e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
HFOGIIHM_01450 1.2e-157 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFOGIIHM_01451 2.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HFOGIIHM_01452 2.3e-30 S Protein of unknown function (DUF2929)
HFOGIIHM_01453 0.0 dnaE 2.7.7.7 L DNA polymerase
HFOGIIHM_01454 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HFOGIIHM_01455 9.3e-169 cvfB S S1 domain
HFOGIIHM_01456 1.7e-165 xerD D recombinase XerD
HFOGIIHM_01457 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFOGIIHM_01458 9e-139 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFOGIIHM_01459 6.5e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFOGIIHM_01460 6.5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFOGIIHM_01461 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
HFOGIIHM_01462 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFOGIIHM_01463 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
HFOGIIHM_01464 6.5e-154 spo0J K Belongs to the ParB family
HFOGIIHM_01465 3.6e-140 soj D Sporulation initiation inhibitor
HFOGIIHM_01466 7.4e-151 noc K Belongs to the ParB family
HFOGIIHM_01467 5.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HFOGIIHM_01468 1.5e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HFOGIIHM_01469 2.7e-171 rihC 3.2.2.1 F Nucleoside
HFOGIIHM_01470 1e-218 nupG F Nucleoside transporter
HFOGIIHM_01471 7.7e-223 cycA E Amino acid permease
HFOGIIHM_01472 8.5e-139 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFOGIIHM_01473 3e-265 glnP P ABC transporter
HFOGIIHM_01474 5.1e-116 frnE Q DSBA-like thioredoxin domain
HFOGIIHM_01475 8.1e-55
HFOGIIHM_01484 4.9e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HFOGIIHM_01485 1.6e-140 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HFOGIIHM_01486 6.5e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFOGIIHM_01487 1.6e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HFOGIIHM_01488 1e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFOGIIHM_01489 2.1e-76 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFOGIIHM_01490 5.6e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFOGIIHM_01491 1.3e-131 IQ reductase
HFOGIIHM_01492 3.3e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HFOGIIHM_01493 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFOGIIHM_01494 3.8e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFOGIIHM_01495 4.2e-77 marR K Transcriptional regulator, MarR family
HFOGIIHM_01496 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFOGIIHM_01498 3.5e-202 xerS L Belongs to the 'phage' integrase family
HFOGIIHM_01499 1.5e-64 L PFAM Integrase catalytic region
HFOGIIHM_01501 2.1e-120 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
HFOGIIHM_01502 4e-162 mleP3 S Membrane transport protein
HFOGIIHM_01503 2.3e-228 4.4.1.8 E Aminotransferase, class I
HFOGIIHM_01504 5.5e-102 M Protein of unknown function (DUF3737)
HFOGIIHM_01505 8.6e-56 yphJ 4.1.1.44 S decarboxylase
HFOGIIHM_01506 7.5e-12 S Oxidoreductase, aldo keto reductase family protein
HFOGIIHM_01507 1.2e-88 C Flavodoxin
HFOGIIHM_01508 1e-159 K Transcriptional regulator
HFOGIIHM_01509 2.3e-85 lacA S transferase hexapeptide repeat
HFOGIIHM_01511 4.3e-132 S Alpha beta hydrolase
HFOGIIHM_01512 2.7e-154 tesE Q hydratase
HFOGIIHM_01513 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HFOGIIHM_01514 7e-228 aadAT EK Aminotransferase, class I
HFOGIIHM_01515 1e-35 ypuA S Protein of unknown function (DUF1002)
HFOGIIHM_01517 0.0 sprD D Domain of Unknown Function (DUF1542)
HFOGIIHM_01518 9e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
HFOGIIHM_01519 3.5e-08 2.7.13.3 T GHKL domain
HFOGIIHM_01520 3.3e-53 L An automated process has identified a potential problem with this gene model
HFOGIIHM_01521 3.6e-85 K FR47-like protein
HFOGIIHM_01522 1.5e-135 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HFOGIIHM_01525 5e-75 osmC O OsmC-like protein
HFOGIIHM_01526 1.3e-171 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFOGIIHM_01527 6.1e-216 patA 2.6.1.1 E Aminotransferase
HFOGIIHM_01528 2.7e-32
HFOGIIHM_01529 0.0 clpL O associated with various cellular activities
HFOGIIHM_01531 0.0 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
HFOGIIHM_01532 6.3e-228 E Amino acid permease
HFOGIIHM_01533 5e-193 nhaC C Na H antiporter NhaC
HFOGIIHM_01534 2.1e-219 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFOGIIHM_01535 4.9e-194 EGP Major facilitator Superfamily
HFOGIIHM_01536 1.1e-120 M Lysin motif
HFOGIIHM_01537 1.6e-79
HFOGIIHM_01538 1.5e-86 P CorA-like Mg2+ transporter protein
HFOGIIHM_01539 6.1e-65 P CorA-like Mg2+ transporter protein
HFOGIIHM_01540 3.1e-95 wecD3 K PFAM GCN5-related N-acetyltransferase
HFOGIIHM_01541 2.5e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HFOGIIHM_01542 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFOGIIHM_01543 0.0 smc D Required for chromosome condensation and partitioning
HFOGIIHM_01544 2.2e-181 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFOGIIHM_01545 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFOGIIHM_01546 2.7e-250 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFOGIIHM_01547 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HFOGIIHM_01548 4.1e-40 ylqC S Belongs to the UPF0109 family
HFOGIIHM_01549 3.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFOGIIHM_01550 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HFOGIIHM_01551 6.8e-262 yfnA E amino acid
HFOGIIHM_01552 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFOGIIHM_01553 2.8e-93
HFOGIIHM_01555 3e-241 yjcE P Sodium proton antiporter
HFOGIIHM_01556 3.6e-57
HFOGIIHM_01558 8e-90
HFOGIIHM_01559 0.0 copA 3.6.3.54 P P-type ATPase
HFOGIIHM_01560 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HFOGIIHM_01561 7.6e-48 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HFOGIIHM_01562 2e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HFOGIIHM_01563 3.2e-164 EG EamA-like transporter family
HFOGIIHM_01564 1.5e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HFOGIIHM_01565 2.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFOGIIHM_01566 2.5e-155 KT YcbB domain
HFOGIIHM_01567 4.3e-98 ywlG S Belongs to the UPF0340 family
HFOGIIHM_01568 6.2e-157 spoU 2.1.1.185 J Methyltransferase
HFOGIIHM_01569 1.1e-223 oxlT P Major Facilitator Superfamily
HFOGIIHM_01570 1.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HFOGIIHM_01572 7.5e-222 S cog cog1373
HFOGIIHM_01573 3.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HFOGIIHM_01574 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFOGIIHM_01575 2.7e-160 EG EamA-like transporter family
HFOGIIHM_01577 7e-184 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HFOGIIHM_01578 4.4e-163 rrmA 2.1.1.187 H Methyltransferase
HFOGIIHM_01579 4.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFOGIIHM_01580 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HFOGIIHM_01581 1.2e-10 S Protein of unknown function (DUF4044)
HFOGIIHM_01582 7.8e-58
HFOGIIHM_01583 3.1e-77 mraZ K Belongs to the MraZ family
HFOGIIHM_01584 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFOGIIHM_01585 1.5e-56 ftsL D Cell division protein FtsL
HFOGIIHM_01586 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HFOGIIHM_01587 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFOGIIHM_01588 2.7e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFOGIIHM_01589 1e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFOGIIHM_01590 3.2e-150 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFOGIIHM_01591 2.9e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFOGIIHM_01592 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFOGIIHM_01593 1.2e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFOGIIHM_01594 8.3e-41 yggT S YGGT family
HFOGIIHM_01595 1.3e-145 ylmH S S4 domain protein
HFOGIIHM_01596 6.4e-38 divIVA D DivIVA domain protein
HFOGIIHM_01597 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFOGIIHM_01598 4.2e-32 cspA K Cold shock protein
HFOGIIHM_01599 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HFOGIIHM_01601 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFOGIIHM_01602 8.3e-218 iscS 2.8.1.7 E Aminotransferase class V
HFOGIIHM_01603 7.5e-58 XK27_04120 S Putative amino acid metabolism
HFOGIIHM_01604 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFOGIIHM_01605 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HFOGIIHM_01606 3.4e-118 S Repeat protein
HFOGIIHM_01607 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFOGIIHM_01608 2.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFOGIIHM_01609 6e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFOGIIHM_01610 7.2e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
HFOGIIHM_01611 1e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFOGIIHM_01612 2.1e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFOGIIHM_01613 7e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFOGIIHM_01614 1.6e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFOGIIHM_01615 2.3e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFOGIIHM_01616 1.3e-221 patA 2.6.1.1 E Aminotransferase
HFOGIIHM_01617 6.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFOGIIHM_01618 1.3e-23 KT Putative sugar diacid recognition
HFOGIIHM_01619 7.4e-42 KT Putative sugar diacid recognition
HFOGIIHM_01620 5.9e-220 EG GntP family permease
HFOGIIHM_01621 5.8e-211 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HFOGIIHM_01622 7.7e-58
HFOGIIHM_01624 4.3e-139 mltD CBM50 M NlpC P60 family protein
HFOGIIHM_01625 5.7e-29
HFOGIIHM_01626 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HFOGIIHM_01627 9.8e-32 ykzG S Belongs to the UPF0356 family
HFOGIIHM_01628 1.4e-81
HFOGIIHM_01629 5.6e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFOGIIHM_01630 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HFOGIIHM_01631 6.2e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HFOGIIHM_01632 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFOGIIHM_01633 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
HFOGIIHM_01634 6.1e-48 yktA S Belongs to the UPF0223 family
HFOGIIHM_01635 5.7e-138 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HFOGIIHM_01636 0.0 typA T GTP-binding protein TypA
HFOGIIHM_01637 8.2e-224 ftsW D Belongs to the SEDS family
HFOGIIHM_01638 1e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HFOGIIHM_01639 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HFOGIIHM_01640 1.1e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFOGIIHM_01641 1.3e-198 ylbL T Belongs to the peptidase S16 family
HFOGIIHM_01642 8.1e-82 comEA L Competence protein ComEA
HFOGIIHM_01643 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
HFOGIIHM_01644 0.0 comEC S Competence protein ComEC
HFOGIIHM_01645 2.5e-149 holA 2.7.7.7 L DNA polymerase III delta subunit
HFOGIIHM_01646 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HFOGIIHM_01647 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFOGIIHM_01648 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFOGIIHM_01649 4.9e-165 S Tetratricopeptide repeat
HFOGIIHM_01650 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFOGIIHM_01651 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFOGIIHM_01652 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFOGIIHM_01653 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HFOGIIHM_01654 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HFOGIIHM_01655 7.6e-09
HFOGIIHM_01656 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFOGIIHM_01657 4.7e-249 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFOGIIHM_01658 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFOGIIHM_01659 1.3e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HFOGIIHM_01660 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HFOGIIHM_01661 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFOGIIHM_01662 2.5e-88
HFOGIIHM_01664 8.4e-130 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFOGIIHM_01665 1.5e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HFOGIIHM_01666 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFOGIIHM_01667 1.3e-35 ynzC S UPF0291 protein
HFOGIIHM_01668 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HFOGIIHM_01669 1.6e-117 plsC 2.3.1.51 I Acyltransferase
HFOGIIHM_01670 3.7e-142 yabB 2.1.1.223 L Methyltransferase small domain
HFOGIIHM_01671 5.4e-49 yazA L GIY-YIG catalytic domain protein
HFOGIIHM_01672 5.2e-184 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFOGIIHM_01673 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HFOGIIHM_01674 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFOGIIHM_01675 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HFOGIIHM_01676 7.4e-95 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFOGIIHM_01677 6.1e-241 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFOGIIHM_01678 1.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HFOGIIHM_01679 5.1e-125 srtA 3.4.22.70 M sortase family
HFOGIIHM_01680 1e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFOGIIHM_01681 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HFOGIIHM_01682 1.5e-118 pgm3 G Belongs to the phosphoglycerate mutase family
HFOGIIHM_01683 2.6e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFOGIIHM_01684 7e-93 lemA S LemA family
HFOGIIHM_01685 1.5e-158 htpX O Belongs to the peptidase M48B family
HFOGIIHM_01686 1.4e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFOGIIHM_01687 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFOGIIHM_01688 1.9e-245 yifK E Amino acid permease
HFOGIIHM_01689 5.6e-294 clcA P chloride
HFOGIIHM_01690 1.8e-34 secG U Preprotein translocase
HFOGIIHM_01691 2.1e-148 est 3.1.1.1 S Serine aminopeptidase, S33
HFOGIIHM_01692 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFOGIIHM_01693 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFOGIIHM_01694 6.3e-105 yxjI
HFOGIIHM_01695 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFOGIIHM_01696 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HFOGIIHM_01697 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HFOGIIHM_01698 6.1e-88 K Acetyltransferase (GNAT) domain
HFOGIIHM_01699 3.1e-181 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFOGIIHM_01701 8.6e-35 S Transglycosylase associated protein
HFOGIIHM_01702 9.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFOGIIHM_01703 4.2e-126 3.1.3.73 G phosphoglycerate mutase
HFOGIIHM_01704 7.5e-115 dedA S SNARE associated Golgi protein
HFOGIIHM_01705 0.0 helD 3.6.4.12 L DNA helicase
HFOGIIHM_01706 1.2e-71 nox C NADH oxidase
HFOGIIHM_01707 1.2e-155 nox C NADH oxidase
HFOGIIHM_01708 1.8e-251 nox C NADH oxidase
HFOGIIHM_01709 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFOGIIHM_01710 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFOGIIHM_01711 2.1e-288 S Psort location CytoplasmicMembrane, score
HFOGIIHM_01712 1.4e-164 yueF S AI-2E family transporter
HFOGIIHM_01713 3.2e-119 S dextransucrase activity
HFOGIIHM_01714 2.1e-224 S Uncharacterised protein family (UPF0236)
HFOGIIHM_01715 2e-120 L PFAM Integrase catalytic region
HFOGIIHM_01716 2.2e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFOGIIHM_01717 2e-127 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFOGIIHM_01718 2.9e-36 L Transposase
HFOGIIHM_01719 0.0 fhaB M Rib/alpha-like repeat
HFOGIIHM_01720 2.4e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HFOGIIHM_01721 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFOGIIHM_01722 4e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
HFOGIIHM_01723 5.1e-116 yjbH Q Thioredoxin
HFOGIIHM_01724 1.5e-269 pipD E Dipeptidase
HFOGIIHM_01725 3.8e-206 coiA 3.6.4.12 S Competence protein
HFOGIIHM_01726 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFOGIIHM_01727 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFOGIIHM_01728 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HFOGIIHM_01748 8.7e-116 lssY 3.6.1.27 I Acid phosphatase homologues
HFOGIIHM_01749 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HFOGIIHM_01750 4.2e-231 clcA_2 P Chloride transporter, ClC family
HFOGIIHM_01751 6.5e-119 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFOGIIHM_01752 4.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFOGIIHM_01753 4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFOGIIHM_01754 1.6e-51
HFOGIIHM_01755 0.0 S SEC-C Motif Domain Protein
HFOGIIHM_01756 7.9e-185 comGA NU Type II IV secretion system protein
HFOGIIHM_01757 2.3e-187 comGB NU type II secretion system
HFOGIIHM_01758 7.1e-47 comGC U competence protein ComGC
HFOGIIHM_01759 4.4e-79 NU general secretion pathway protein
HFOGIIHM_01760 4.8e-45
HFOGIIHM_01761 3.6e-73
HFOGIIHM_01763 7.7e-146 ytxK 2.1.1.72 L N-6 DNA Methylase
HFOGIIHM_01764 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFOGIIHM_01765 8.8e-118 S Calcineurin-like phosphoesterase
HFOGIIHM_01766 4.4e-100 yutD S Protein of unknown function (DUF1027)
HFOGIIHM_01767 2.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFOGIIHM_01768 2.8e-114 S Protein of unknown function (DUF1461)
HFOGIIHM_01769 5.5e-110 dedA S SNARE-like domain protein
HFOGIIHM_01770 2.5e-157 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFOGIIHM_01772 1.9e-36 K Transcriptional regulator, HxlR family
HFOGIIHM_01774 3e-37
HFOGIIHM_01775 1e-83 K DNA-templated transcription, initiation
HFOGIIHM_01776 2.9e-32
HFOGIIHM_01777 7.8e-80
HFOGIIHM_01778 3.9e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFOGIIHM_01779 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HFOGIIHM_01780 0.0 yjbQ P TrkA C-terminal domain protein
HFOGIIHM_01781 7.4e-277 pipD E Dipeptidase
HFOGIIHM_01782 3.1e-103 M NlpC P60 family protein
HFOGIIHM_01783 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HFOGIIHM_01784 7.8e-38 L Helix-turn-helix domain
HFOGIIHM_01785 1.1e-115 L PFAM Integrase, catalytic core
HFOGIIHM_01786 2.5e-96 L Helix-turn-helix domain
HFOGIIHM_01787 1.7e-57 L PFAM Integrase catalytic region
HFOGIIHM_01788 2.1e-29 L Transposase
HFOGIIHM_01789 1.3e-246 L Transposase
HFOGIIHM_01790 6.6e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFOGIIHM_01791 1.6e-105 ypsA S Belongs to the UPF0398 family
HFOGIIHM_01792 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFOGIIHM_01793 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HFOGIIHM_01794 1.4e-162 EG EamA-like transporter family
HFOGIIHM_01795 8.6e-125 dnaD L DnaD domain protein
HFOGIIHM_01796 1.8e-87 ypmB S Protein conserved in bacteria
HFOGIIHM_01797 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HFOGIIHM_01798 2.1e-174 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HFOGIIHM_01799 1.7e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HFOGIIHM_01800 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HFOGIIHM_01801 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFOGIIHM_01802 3.9e-87 S Protein of unknown function (DUF1440)
HFOGIIHM_01803 0.0 rafA 3.2.1.22 G alpha-galactosidase
HFOGIIHM_01804 2e-191 galR K Periplasmic binding protein-like domain
HFOGIIHM_01805 4.4e-47 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HFOGIIHM_01806 6.3e-87 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HFOGIIHM_01807 6.4e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFOGIIHM_01808 4.5e-124 lrgB M LrgB-like family
HFOGIIHM_01809 1.9e-66 lrgA S LrgA family
HFOGIIHM_01810 1.1e-130 lytT K response regulator receiver
HFOGIIHM_01811 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HFOGIIHM_01812 4e-148 f42a O Band 7 protein
HFOGIIHM_01813 1.1e-261 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HFOGIIHM_01814 6.4e-156 yitU 3.1.3.104 S hydrolase
HFOGIIHM_01815 9.2e-39 S Cytochrome B5
HFOGIIHM_01816 9.8e-115 nreC K PFAM regulatory protein LuxR
HFOGIIHM_01817 1.2e-160 hipB K Helix-turn-helix
HFOGIIHM_01818 2.8e-57 yitW S Iron-sulfur cluster assembly protein
HFOGIIHM_01819 1.4e-270 sufB O assembly protein SufB
HFOGIIHM_01820 3.2e-80 nifU C SUF system FeS assembly protein, NifU family
HFOGIIHM_01821 9.5e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFOGIIHM_01822 7.8e-241 sufD O FeS assembly protein SufD
HFOGIIHM_01823 6.5e-145 sufC O FeS assembly ATPase SufC
HFOGIIHM_01824 1.2e-31 feoA P FeoA domain
HFOGIIHM_01825 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HFOGIIHM_01826 1.6e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HFOGIIHM_01827 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HFOGIIHM_01828 8.5e-63 ydiI Q Thioesterase superfamily
HFOGIIHM_01829 2.4e-109 yvrI K sigma factor activity
HFOGIIHM_01830 2.1e-200 G Transporter, major facilitator family protein
HFOGIIHM_01831 0.0 S Bacterial membrane protein YfhO
HFOGIIHM_01832 3e-104 T Ion transport 2 domain protein
HFOGIIHM_01833 8.4e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HFOGIIHM_01835 0.0 L PLD-like domain
HFOGIIHM_01836 6.4e-61 mrr L restriction endonuclease
HFOGIIHM_01837 2.4e-151 L restriction endonuclease
HFOGIIHM_01838 2.1e-53 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
HFOGIIHM_01839 1.4e-44 S RelE-like toxin of type II toxin-antitoxin system HigB
HFOGIIHM_01840 2.6e-38 higA K Helix-turn-helix XRE-family like proteins
HFOGIIHM_01841 1.9e-121 3.1.21.3 L Type I restriction modification DNA specificity domain
HFOGIIHM_01842 8.9e-178 L Belongs to the 'phage' integrase family
HFOGIIHM_01843 1.6e-59 3.1.21.3 V Type I restriction modification DNA specificity domain
HFOGIIHM_01844 4.6e-294 hsdM 2.1.1.72 V type I restriction-modification system
HFOGIIHM_01845 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HFOGIIHM_01846 6.2e-140 IQ reductase
HFOGIIHM_01847 2.8e-58 yhaI S Protein of unknown function (DUF805)
HFOGIIHM_01848 2.2e-44
HFOGIIHM_01849 0.0 nylA 3.5.1.4 J Belongs to the amidase family
HFOGIIHM_01850 3.1e-22
HFOGIIHM_01851 4.2e-47
HFOGIIHM_01852 2.2e-96 K Acetyltransferase (GNAT) domain
HFOGIIHM_01853 4.5e-296 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HFOGIIHM_01854 1.3e-233 gntT EG Gluconate
HFOGIIHM_01855 5.2e-184 K Transcriptional regulator, LacI family
HFOGIIHM_01856 1.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HFOGIIHM_01857 7.2e-95
HFOGIIHM_01858 2.3e-24
HFOGIIHM_01859 8.7e-63 asp S Asp23 family, cell envelope-related function
HFOGIIHM_01860 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HFOGIIHM_01862 2.7e-49
HFOGIIHM_01863 8.3e-69 yqkB S Belongs to the HesB IscA family
HFOGIIHM_01864 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HFOGIIHM_01865 1.7e-84 F NUDIX domain
HFOGIIHM_01866 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFOGIIHM_01867 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFOGIIHM_01868 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFOGIIHM_01869 5.3e-61 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFOGIIHM_01870 5.8e-233 L transposase, IS605 OrfB family
HFOGIIHM_01871 6.7e-114 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFOGIIHM_01872 8.2e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HFOGIIHM_01873 4.7e-180 yagE E amino acid
HFOGIIHM_01874 2.6e-85 dps P Belongs to the Dps family
HFOGIIHM_01875 0.0 pacL 3.6.3.8 P P-type ATPase
HFOGIIHM_01876 8.4e-93 L nuclease
HFOGIIHM_01877 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HFOGIIHM_01878 5.1e-69
HFOGIIHM_01879 7.5e-103 fic D Fic/DOC family
HFOGIIHM_01880 1.1e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFOGIIHM_01881 1.5e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HFOGIIHM_01882 8.4e-31
HFOGIIHM_01883 2.8e-185
HFOGIIHM_01884 1.7e-23
HFOGIIHM_01885 1.4e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFOGIIHM_01886 9e-253 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFOGIIHM_01887 7e-217 iscS2 2.8.1.7 E Aminotransferase class V
HFOGIIHM_01888 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFOGIIHM_01889 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFOGIIHM_01890 7e-44 M Leucine-rich repeat (LRR) protein
HFOGIIHM_01891 1.6e-78 L PFAM Integrase catalytic region
HFOGIIHM_01892 2.8e-44 L transposase and inactivated derivatives, IS30 family
HFOGIIHM_01893 4.4e-180
HFOGIIHM_01894 1.2e-76
HFOGIIHM_01895 5.9e-88 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HFOGIIHM_01897 4.6e-41 rpmE2 J Ribosomal protein L31
HFOGIIHM_01898 8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFOGIIHM_01899 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFOGIIHM_01900 8.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFOGIIHM_01901 1.2e-67 ywiB S Domain of unknown function (DUF1934)
HFOGIIHM_01902 1.4e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HFOGIIHM_01903 1e-270 ywfO S HD domain protein
HFOGIIHM_01904 5e-148 yxeH S hydrolase
HFOGIIHM_01905 6.1e-185 ansA 3.5.1.1 EJ L-asparaginase, type I
HFOGIIHM_01906 1.1e-156 K Transcriptional regulator
HFOGIIHM_01907 1.2e-163 akr5f 1.1.1.346 S reductase
HFOGIIHM_01908 1.8e-104 K Transcriptional regulator C-terminal region
HFOGIIHM_01909 2.1e-189 S membrane
HFOGIIHM_01910 1.6e-114 GM NAD(P)H-binding
HFOGIIHM_01911 1.1e-64 yneR
HFOGIIHM_01912 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
HFOGIIHM_01913 5.5e-261 G Major Facilitator
HFOGIIHM_01914 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HFOGIIHM_01915 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HFOGIIHM_01916 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HFOGIIHM_01917 0.0 lacS G Transporter
HFOGIIHM_01918 5.1e-187 lacR K Transcriptional regulator
HFOGIIHM_01919 9.5e-83
HFOGIIHM_01920 1.9e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFOGIIHM_01921 2.1e-198 XK27_09615 S reductase
HFOGIIHM_01922 5.4e-101 nqr 1.5.1.36 S reductase
HFOGIIHM_01924 1.3e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFOGIIHM_01925 1.5e-183 K Transcriptional regulator, LacI family
HFOGIIHM_01926 5.1e-220 yxjG_1 E methionine synthase, vitamin-B12 independent
HFOGIIHM_01927 1.5e-143 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
HFOGIIHM_01928 6.8e-159 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HFOGIIHM_01929 1.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFOGIIHM_01930 1.1e-48 L Belongs to the 'phage' integrase family
HFOGIIHM_01934 8.1e-76 E IrrE N-terminal-like domain
HFOGIIHM_01935 1.4e-48 K Cro/C1-type HTH DNA-binding domain
HFOGIIHM_01936 1.3e-20
HFOGIIHM_01937 9.6e-111 S Protein of unknown function (DUF3102)
HFOGIIHM_01939 9.2e-08
HFOGIIHM_01943 6.4e-07
HFOGIIHM_01945 1.2e-54 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFOGIIHM_01946 6e-131 S Putative HNHc nuclease
HFOGIIHM_01947 8.1e-128 L Psort location Cytoplasmic, score
HFOGIIHM_01949 5.4e-24
HFOGIIHM_01950 9.3e-32
HFOGIIHM_01951 1.2e-74 rusA L Endodeoxyribonuclease RusA
HFOGIIHM_01958 1.1e-138
HFOGIIHM_01964 6.6e-72
HFOGIIHM_01965 6.8e-26
HFOGIIHM_01966 1.8e-130 dck 2.7.1.74 F deoxynucleoside kinase
HFOGIIHM_01971 1.9e-74 S Transcriptional regulator, RinA family
HFOGIIHM_01973 0.0
HFOGIIHM_01974 8.5e-211 XK27_11280 S Psort location CytoplasmicMembrane, score
HFOGIIHM_01986 2.1e-102 pnuC H nicotinamide mononucleotide transporter
HFOGIIHM_01988 3.7e-26 S AAA ATPase domain
HFOGIIHM_02002 3.2e-53 L HNH nucleases
HFOGIIHM_02003 2.7e-79 L Phage terminase, small subunit
HFOGIIHM_02004 3e-267 S Phage Terminase
HFOGIIHM_02006 2.3e-147 S portal protein
HFOGIIHM_02007 1.8e-82 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HFOGIIHM_02008 6.9e-140 S Phage capsid family
HFOGIIHM_02009 5.7e-45 S Phage gp6-like head-tail connector protein
HFOGIIHM_02010 6.9e-38 S Phage head-tail joining protein
HFOGIIHM_02011 4.8e-20
HFOGIIHM_02012 9.8e-25
HFOGIIHM_02013 1.8e-66 S Phage tail tube protein
HFOGIIHM_02014 4e-18
HFOGIIHM_02015 0.0 M Phage tail tape measure protein TP901
HFOGIIHM_02016 1.2e-141 S Phage tail protein
HFOGIIHM_02017 3e-294 M Prophage endopeptidase tail
HFOGIIHM_02018 2.8e-35
HFOGIIHM_02020 1.7e-74 S Domain of unknown function (DUF2479)
HFOGIIHM_02025 2e-14
HFOGIIHM_02026 4e-54 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HFOGIIHM_02027 1.3e-130 3.5.1.104 M hydrolase, family 25
HFOGIIHM_02029 2e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFOGIIHM_02030 8.2e-193 ypbB 5.1.3.1 S Helix-turn-helix domain
HFOGIIHM_02031 2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HFOGIIHM_02032 7.5e-18 M Lysin motif
HFOGIIHM_02033 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HFOGIIHM_02034 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HFOGIIHM_02035 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HFOGIIHM_02036 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFOGIIHM_02037 8.8e-237 S Tetratricopeptide repeat protein
HFOGIIHM_02038 3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFOGIIHM_02039 0.0 yfmR S ABC transporter, ATP-binding protein
HFOGIIHM_02040 7.7e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFOGIIHM_02041 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFOGIIHM_02042 5.3e-113 hlyIII S protein, hemolysin III
HFOGIIHM_02043 9.9e-152 DegV S EDD domain protein, DegV family
HFOGIIHM_02044 1.8e-170 ypmR E lipolytic protein G-D-S-L family
HFOGIIHM_02045 1.3e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HFOGIIHM_02046 4.4e-35 yozE S Belongs to the UPF0346 family
HFOGIIHM_02047 1.9e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFOGIIHM_02048 4.5e-143 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFOGIIHM_02049 1.7e-162 dprA LU DNA protecting protein DprA
HFOGIIHM_02050 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFOGIIHM_02051 1e-167 lacX 5.1.3.3 G Aldose 1-epimerase
HFOGIIHM_02053 5.4e-178 M Glycosyltransferase like family 2
HFOGIIHM_02054 3e-27
HFOGIIHM_02055 1.7e-134 M repeat protein
HFOGIIHM_02056 1.6e-156 3.2.1.96, 3.5.1.28 GH73 M repeat protein
HFOGIIHM_02057 1e-47 gcvH E glycine cleavage
HFOGIIHM_02058 1.1e-220 rodA D Belongs to the SEDS family
HFOGIIHM_02059 2.7e-32 S Protein of unknown function (DUF2969)
HFOGIIHM_02060 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HFOGIIHM_02061 7.2e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFOGIIHM_02062 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HFOGIIHM_02063 2.6e-219 L Transposase
HFOGIIHM_02065 1.6e-121 S Double zinc ribbon
HFOGIIHM_02066 4.7e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HFOGIIHM_02067 1.4e-181 iunH2 3.2.2.1 F nucleoside hydrolase
HFOGIIHM_02068 1.2e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HFOGIIHM_02069 3e-143 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HFOGIIHM_02070 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
HFOGIIHM_02071 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HFOGIIHM_02072 1.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HFOGIIHM_02073 3.4e-77 ctsR K Belongs to the CtsR family
HFOGIIHM_02074 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFOGIIHM_02075 3.1e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HFOGIIHM_02076 1.2e-141 mdtG EGP Major facilitator Superfamily
HFOGIIHM_02077 2.5e-68 mdtG EGP Major facilitator Superfamily
HFOGIIHM_02078 2.1e-165 T Calcineurin-like phosphoesterase superfamily domain
HFOGIIHM_02079 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFOGIIHM_02081 7e-192 L Transposase
HFOGIIHM_02082 3.9e-21 rnhA 3.1.26.4 L Caulimovirus viroplasmin
HFOGIIHM_02083 3.9e-90 D CobQ CobB MinD ParA nucleotide binding domain protein
HFOGIIHM_02085 1.4e-295 aspT P Predicted Permease Membrane Region
HFOGIIHM_02086 3.3e-310 asdA 4.1.1.12 E Aminotransferase
HFOGIIHM_02087 2.5e-124 glsA 3.5.1.2 E Belongs to the glutaminase family
HFOGIIHM_02088 1.1e-186 iolS C Aldo keto reductase
HFOGIIHM_02089 3.5e-293 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HFOGIIHM_02090 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
HFOGIIHM_02091 5.1e-81 uspA T universal stress protein
HFOGIIHM_02092 0.0 tetP J elongation factor G
HFOGIIHM_02093 4.4e-166 GK ROK family
HFOGIIHM_02094 2.8e-241 brnQ U Component of the transport system for branched-chain amino acids
HFOGIIHM_02095 1.7e-139 aroD S Serine hydrolase (FSH1)
HFOGIIHM_02096 1.1e-242 yagE E amino acid
HFOGIIHM_02097 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HFOGIIHM_02098 7.3e-126 I transferase activity, transferring acyl groups other than amino-acyl groups
HFOGIIHM_02099 3.4e-132 gntR K UbiC transcription regulator-associated domain protein
HFOGIIHM_02100 6.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFOGIIHM_02101 7.5e-285 pipD E Dipeptidase
HFOGIIHM_02102 0.0 yfiC V ABC transporter
HFOGIIHM_02103 1.1e-309 lmrA V ABC transporter, ATP-binding protein
HFOGIIHM_02104 1.4e-187 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFOGIIHM_02105 1.2e-81 S ECF transporter, substrate-specific component
HFOGIIHM_02106 9.6e-62 S Domain of unknown function (DUF4430)
HFOGIIHM_02107 6.5e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HFOGIIHM_02108 5.3e-130 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HFOGIIHM_02109 7e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
HFOGIIHM_02110 9.9e-135 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HFOGIIHM_02111 3e-102 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
HFOGIIHM_02112 9.3e-250 hemL 5.4.3.8 H Aminotransferase class-III
HFOGIIHM_02113 3.8e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
HFOGIIHM_02114 6.5e-165 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HFOGIIHM_02115 1.8e-229 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HFOGIIHM_02116 7.9e-79 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
HFOGIIHM_02117 2.2e-274 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HFOGIIHM_02118 6.3e-148 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
HFOGIIHM_02119 5.4e-116 cbiQ P Cobalt transport protein
HFOGIIHM_02120 1.9e-52 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HFOGIIHM_02121 2.4e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HFOGIIHM_02122 3.9e-125 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HFOGIIHM_02123 4.4e-146 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
HFOGIIHM_02124 1.1e-259 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HFOGIIHM_02125 6.4e-134 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
HFOGIIHM_02126 1.3e-131 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HFOGIIHM_02127 5.5e-192 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
HFOGIIHM_02128 6.4e-134 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HFOGIIHM_02129 5.1e-96 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HFOGIIHM_02130 3.3e-109 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HFOGIIHM_02131 1.6e-208 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HFOGIIHM_02132 9.2e-124 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
HFOGIIHM_02133 5.7e-180 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HFOGIIHM_02134 4.1e-264 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HFOGIIHM_02135 2.1e-207 cobD 4.1.1.81 E Aminotransferase class I and II
HFOGIIHM_02136 8.2e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
HFOGIIHM_02137 1.5e-155 XK27_04590 S NADPH-dependent FMN reductase
HFOGIIHM_02138 3.9e-78 fld C Flavodoxin
HFOGIIHM_02139 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
HFOGIIHM_02140 6.7e-80 P Cadmium resistance transporter
HFOGIIHM_02141 1.3e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
HFOGIIHM_02142 1.4e-147 3.1.3.48 T Pfam:Y_phosphatase3C
HFOGIIHM_02143 5.5e-56 pduU E BMC
HFOGIIHM_02144 2.2e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFOGIIHM_02145 2.4e-209 pduQ C Iron-containing alcohol dehydrogenase
HFOGIIHM_02146 3.4e-269 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HFOGIIHM_02147 7.4e-80 pduO S Haem-degrading
HFOGIIHM_02148 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HFOGIIHM_02149 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HFOGIIHM_02150 1.1e-89 S Putative propanediol utilisation
HFOGIIHM_02151 2.1e-117 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HFOGIIHM_02152 7.6e-43 pduA_4 CQ BMC
HFOGIIHM_02153 1.4e-72 pduK CQ BMC
HFOGIIHM_02154 3.2e-59 pduH S Dehydratase medium subunit
HFOGIIHM_02155 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
HFOGIIHM_02156 3.7e-77 pduE 4.2.1.28 Q Dehydratase small subunit
HFOGIIHM_02157 1.1e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HFOGIIHM_02158 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HFOGIIHM_02159 2.7e-134 pduB E BMC
HFOGIIHM_02160 6.2e-42 pduA_4 CQ BMC
HFOGIIHM_02161 4.7e-199 K helix_turn_helix, arabinose operon control protein
HFOGIIHM_02162 1.7e-159 rssA S Phospholipase, patatin family
HFOGIIHM_02163 2.5e-118 L Integrase
HFOGIIHM_02164 2.9e-154 EG EamA-like transporter family
HFOGIIHM_02165 3e-75
HFOGIIHM_02166 3e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HFOGIIHM_02167 3.1e-131 ponA V Beta-lactamase enzyme family
HFOGIIHM_02168 1.6e-280 L Transposase IS66 family
HFOGIIHM_02169 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
HFOGIIHM_02173 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFOGIIHM_02174 3.3e-46 L Belongs to the 'phage' integrase family
HFOGIIHM_02175 1e-25 S Phage derived protein Gp49-like (DUF891)
HFOGIIHM_02178 8.8e-161 xth 3.1.11.2 L exodeoxyribonuclease III
HFOGIIHM_02179 4.4e-55 S Mazg nucleotide pyrophosphohydrolase
HFOGIIHM_02180 7.7e-35
HFOGIIHM_02181 2.6e-234 pbuG S permease
HFOGIIHM_02182 3.2e-121 L hmm pf00665
HFOGIIHM_02183 1.9e-127 L Helix-turn-helix domain
HFOGIIHM_02184 1.3e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HFOGIIHM_02186 2.8e-19
HFOGIIHM_02187 1.3e-263 dtpT U amino acid peptide transporter
HFOGIIHM_02188 5.2e-161 yjjH S Calcineurin-like phosphoesterase
HFOGIIHM_02191 1.5e-115
HFOGIIHM_02192 1.3e-252 EGP Major facilitator Superfamily
HFOGIIHM_02193 3.2e-303 aspT P Predicted Permease Membrane Region
HFOGIIHM_02194 2.5e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HFOGIIHM_02195 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
HFOGIIHM_02196 1.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFOGIIHM_02197 6.7e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFOGIIHM_02198 0.0 yhgF K Tex-like protein N-terminal domain protein
HFOGIIHM_02199 8.6e-86 ydcK S Belongs to the SprT family
HFOGIIHM_02201 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HFOGIIHM_02202 2.8e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HFOGIIHM_02203 0.0 S Bacterial membrane protein, YfhO
HFOGIIHM_02204 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFOGIIHM_02205 7e-169 I alpha/beta hydrolase fold
HFOGIIHM_02206 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HFOGIIHM_02207 1.1e-119 tcyB E ABC transporter
HFOGIIHM_02208 2.6e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFOGIIHM_02209 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HFOGIIHM_02210 1.6e-268 pepC 3.4.22.40 E Peptidase C1-like family
HFOGIIHM_02211 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFOGIIHM_02212 8.5e-50 HA62_12640 S GCN5-related N-acetyl-transferase
HFOGIIHM_02213 2.3e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HFOGIIHM_02214 3.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFOGIIHM_02215 1e-207 yacL S domain protein
HFOGIIHM_02216 1.3e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFOGIIHM_02217 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFOGIIHM_02218 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFOGIIHM_02219 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HFOGIIHM_02220 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFOGIIHM_02221 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HFOGIIHM_02222 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFOGIIHM_02223 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFOGIIHM_02224 1.6e-227 aadAT EK Aminotransferase, class I
HFOGIIHM_02226 1.8e-248 M Glycosyl transferase family group 2
HFOGIIHM_02227 4e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFOGIIHM_02228 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFOGIIHM_02229 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFOGIIHM_02230 7.7e-48
HFOGIIHM_02232 9.4e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFOGIIHM_02233 2.4e-56 K transcriptional regulator PadR family
HFOGIIHM_02234 5.6e-80 XK27_06920 S Protein of unknown function (DUF1700)
HFOGIIHM_02235 8.3e-134 S Putative adhesin
HFOGIIHM_02236 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HFOGIIHM_02237 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFOGIIHM_02238 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFOGIIHM_02239 3.4e-35 nrdH O Glutaredoxin
HFOGIIHM_02240 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFOGIIHM_02241 4.9e-281 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFOGIIHM_02242 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFOGIIHM_02243 3.7e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFOGIIHM_02244 9.7e-39 S Protein of unknown function (DUF2508)
HFOGIIHM_02245 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFOGIIHM_02246 7.6e-52 yaaQ S Cyclic-di-AMP receptor
HFOGIIHM_02247 8.2e-185 holB 2.7.7.7 L DNA polymerase III
HFOGIIHM_02248 5.9e-58 yabA L Involved in initiation control of chromosome replication
HFOGIIHM_02249 1.4e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFOGIIHM_02250 2.8e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
HFOGIIHM_02251 2.7e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HFOGIIHM_02252 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFOGIIHM_02253 3.6e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HFOGIIHM_02254 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HFOGIIHM_02255 2.1e-79 L hmm pf00665
HFOGIIHM_02256 5.8e-106 L Helix-turn-helix domain
HFOGIIHM_02257 3.7e-157 isp2 L Transposase
HFOGIIHM_02258 1.6e-238 L Integrase core domain
HFOGIIHM_02259 5.6e-138 IQ KR domain
HFOGIIHM_02269 1.2e-197 L COG2826 Transposase and inactivated derivatives, IS30 family
HFOGIIHM_02270 5e-167 I alpha/beta hydrolase fold
HFOGIIHM_02271 1.2e-199 L COG2826 Transposase and inactivated derivatives, IS30 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)