ORF_ID e_value Gene_name EC_number CAZy COGs Description
LCAHJLOB_00001 1.1e-80 L Helix-turn-helix domain
LCAHJLOB_00002 3.2e-145 L Integrase core domain protein
LCAHJLOB_00003 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LCAHJLOB_00004 3.1e-69 argR K Regulates arginine biosynthesis genes
LCAHJLOB_00005 5.7e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LCAHJLOB_00006 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LCAHJLOB_00007 5.1e-78 S Protein of unknown function (DUF3021)
LCAHJLOB_00008 4.2e-69 K LytTr DNA-binding domain
LCAHJLOB_00010 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LCAHJLOB_00012 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LCAHJLOB_00013 2.4e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
LCAHJLOB_00014 2e-228 cinA 3.5.1.42 S Belongs to the CinA family
LCAHJLOB_00015 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCAHJLOB_00016 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
LCAHJLOB_00022 2.6e-10
LCAHJLOB_00028 4.9e-111 mreC M Involved in formation and maintenance of cell shape
LCAHJLOB_00029 1e-82 mreD M rod shape-determining protein MreD
LCAHJLOB_00030 1.6e-83 usp 3.5.1.28 CBM50 S CHAP domain
LCAHJLOB_00031 4.7e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCAHJLOB_00032 1.8e-215 araT 2.6.1.1 E Aminotransferase
LCAHJLOB_00033 4.8e-137 recO L Involved in DNA repair and RecF pathway recombination
LCAHJLOB_00034 1.3e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LCAHJLOB_00035 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCAHJLOB_00036 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LCAHJLOB_00037 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCAHJLOB_00038 1.4e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LCAHJLOB_00039 9.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LCAHJLOB_00040 2.6e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LCAHJLOB_00041 1.4e-147
LCAHJLOB_00042 1.1e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LCAHJLOB_00043 4.2e-68
LCAHJLOB_00044 7.8e-157 S CHAP domain
LCAHJLOB_00045 6.7e-237 purD 6.3.4.13 F Belongs to the GARS family
LCAHJLOB_00046 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LCAHJLOB_00047 7.9e-202 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCAHJLOB_00048 1.6e-174 1.1.1.169 H Ketopantoate reductase
LCAHJLOB_00049 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LCAHJLOB_00050 1.9e-88 L COG1943 Transposase and inactivated derivatives
LCAHJLOB_00051 3.6e-31 L Integrase core domain protein
LCAHJLOB_00052 2.1e-78 sraP UW Hep Hag repeat protein
LCAHJLOB_00053 0.0 sraP UW Hep Hag repeat protein
LCAHJLOB_00054 9.5e-186 nss M transferase activity, transferring glycosyl groups
LCAHJLOB_00055 3.6e-16 S Accessory secretory protein Sec, Asp5
LCAHJLOB_00056 2.6e-17 S Accessory secretory protein Sec Asp4
LCAHJLOB_00057 4.6e-244 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
LCAHJLOB_00058 6.3e-282 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
LCAHJLOB_00059 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LCAHJLOB_00060 6.5e-78 asp3 S Accessory Sec system protein Asp3
LCAHJLOB_00061 1.6e-285 asp2 3.4.11.5 S Accessory Sec system protein Asp2
LCAHJLOB_00062 1.2e-288 asp1 S Accessory Sec system protein Asp1
LCAHJLOB_00063 1.2e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
LCAHJLOB_00064 0.0 M family 8
LCAHJLOB_00065 0.0 sbcC L ATPase involved in DNA repair
LCAHJLOB_00066 1e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LCAHJLOB_00067 0.0 GM domain, Protein
LCAHJLOB_00068 0.0 zmpB M signal peptide protein, YSIRK family
LCAHJLOB_00069 0.0 M domain protein
LCAHJLOB_00070 1.7e-10
LCAHJLOB_00071 8.2e-189 XK27_10075 S abc transporter atp-binding protein
LCAHJLOB_00072 0.0 V abc transporter atp-binding protein
LCAHJLOB_00073 5.2e-296 V abc transporter atp-binding protein
LCAHJLOB_00074 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
LCAHJLOB_00076 4.9e-282 S Protein of unknown function (DUF3114)
LCAHJLOB_00077 1.5e-100 2.3.1.128 K Acetyltransferase GNAT Family
LCAHJLOB_00078 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LCAHJLOB_00079 2.3e-281 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
LCAHJLOB_00080 5.4e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
LCAHJLOB_00081 6.4e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LCAHJLOB_00082 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LCAHJLOB_00083 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LCAHJLOB_00084 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LCAHJLOB_00085 6.2e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LCAHJLOB_00086 1.2e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LCAHJLOB_00087 4.9e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LCAHJLOB_00090 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LCAHJLOB_00091 6.3e-169 vraS 2.7.13.3 T Histidine kinase
LCAHJLOB_00092 1.9e-116 yvqF S Membrane
LCAHJLOB_00093 1e-94 kcsA P Ion transport protein
LCAHJLOB_00094 2.3e-294 prkC 2.7.11.1 KLT serine threonine protein kinase
LCAHJLOB_00095 2e-135 stp 3.1.3.16 T phosphatase
LCAHJLOB_00096 5e-243 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCAHJLOB_00097 2.4e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LCAHJLOB_00098 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCAHJLOB_00099 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
LCAHJLOB_00100 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LCAHJLOB_00101 3.8e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LCAHJLOB_00102 2.7e-146 XK27_02985 S overlaps another CDS with the same product name
LCAHJLOB_00103 2.6e-146 supH S overlaps another CDS with the same product name
LCAHJLOB_00104 5.6e-62 yvoA_1 K Transcriptional
LCAHJLOB_00105 2.4e-119 skfE V abc transporter atp-binding protein
LCAHJLOB_00106 5.3e-131 V Psort location CytoplasmicMembrane, score
LCAHJLOB_00107 2.1e-171 oppF P Belongs to the ABC transporter superfamily
LCAHJLOB_00108 4.6e-202 oppD P Belongs to the ABC transporter superfamily
LCAHJLOB_00109 3.8e-165 amiD P ABC transporter (Permease
LCAHJLOB_00110 2.7e-277 amiC P ABC transporter (Permease
LCAHJLOB_00111 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
LCAHJLOB_00112 0.0 amiA E ABC transporter, substrate-binding protein, family 5
LCAHJLOB_00113 2.4e-173 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LCAHJLOB_00114 4.5e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LCAHJLOB_00115 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LCAHJLOB_00116 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
LCAHJLOB_00117 2.4e-101 yjbK S Adenylate cyclase
LCAHJLOB_00118 8.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCAHJLOB_00119 6.4e-207 iscS 2.8.1.7 E Cysteine desulfurase
LCAHJLOB_00120 8.2e-60 XK27_04120 S Putative amino acid metabolism
LCAHJLOB_00121 1.5e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LCAHJLOB_00122 4.4e-129 puuD T peptidase C26
LCAHJLOB_00123 2.6e-118 radC E Belongs to the UPF0758 family
LCAHJLOB_00124 1.1e-287 rgpF M Rhamnan synthesis protein F
LCAHJLOB_00125 6.2e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LCAHJLOB_00126 4.4e-141 rgpC GM Transport permease protein
LCAHJLOB_00127 4.3e-172 rgpB GT2 M Glycosyltransferase, group 2 family protein
LCAHJLOB_00128 6.5e-223 rgpA GT4 M Domain of unknown function (DUF1972)
LCAHJLOB_00129 3.2e-223 GT4 M transferase activity, transferring glycosyl groups
LCAHJLOB_00130 3.6e-219 M Psort location CytoplasmicMembrane, score
LCAHJLOB_00131 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
LCAHJLOB_00132 6.9e-109
LCAHJLOB_00133 7.5e-154 2.4.1.60 S Glycosyltransferase group 2 family protein
LCAHJLOB_00134 1.6e-42 S Uncharacterized conserved protein (DUF2304)
LCAHJLOB_00135 4.1e-127 arnC M group 2 family protein
LCAHJLOB_00136 1.7e-179 cpsIaJ S Glycosyltransferase like family 2
LCAHJLOB_00137 3.2e-175 M Glycosyltransferase, group 2 family protein
LCAHJLOB_00138 3.9e-221 amrA S membrane protein involved in the export of O-antigen and teichoic acid
LCAHJLOB_00139 2.9e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LCAHJLOB_00140 3.1e-257 S Glucosyl transferase GtrII
LCAHJLOB_00141 1.2e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
LCAHJLOB_00142 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
LCAHJLOB_00143 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LCAHJLOB_00144 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LCAHJLOB_00145 4.2e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LCAHJLOB_00146 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LCAHJLOB_00147 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
LCAHJLOB_00148 1.3e-199 arcT 2.6.1.1 E Aminotransferase
LCAHJLOB_00149 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
LCAHJLOB_00150 2.2e-140 ET ABC transporter
LCAHJLOB_00151 1.8e-78 mutT 3.6.1.55 F Nudix family
LCAHJLOB_00152 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LCAHJLOB_00154 7.3e-164 S CAAX amino terminal protease family protein
LCAHJLOB_00155 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
LCAHJLOB_00156 1.1e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
LCAHJLOB_00157 1.7e-17 XK27_00735
LCAHJLOB_00158 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LCAHJLOB_00160 9.6e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LCAHJLOB_00161 3.4e-10 O ADP-ribosylglycohydrolase
LCAHJLOB_00162 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
LCAHJLOB_00163 1.9e-62 ycaO O OsmC-like protein
LCAHJLOB_00165 1.8e-151 EG Permeases of the drug metabolite transporter (DMT) superfamily
LCAHJLOB_00166 3.2e-07 N PFAM Uncharacterised protein family UPF0150
LCAHJLOB_00167 2.9e-111 serB 3.1.3.3 E phosphoserine phosphatase
LCAHJLOB_00168 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LCAHJLOB_00169 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCAHJLOB_00170 5.5e-98 3.1.3.18 S IA, variant 1
LCAHJLOB_00171 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LCAHJLOB_00172 3.5e-56 lrgA S Effector of murein hydrolase LrgA
LCAHJLOB_00174 1.6e-58 arsC 1.20.4.1 P Belongs to the ArsC family
LCAHJLOB_00175 8.3e-74 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
LCAHJLOB_00176 5.9e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCAHJLOB_00177 1.3e-104 wecD M Acetyltransferase (GNAT) domain
LCAHJLOB_00178 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LCAHJLOB_00179 7.3e-153 GK ROK family
LCAHJLOB_00180 6.9e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
LCAHJLOB_00181 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
LCAHJLOB_00182 4.1e-203 potD P spermidine putrescine ABC transporter
LCAHJLOB_00183 2.6e-130 potC P ABC-type spermidine putrescine transport system, permease component II
LCAHJLOB_00184 1.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
LCAHJLOB_00185 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LCAHJLOB_00186 3.4e-166 murB 1.3.1.98 M cell wall formation
LCAHJLOB_00187 2.1e-77 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LCAHJLOB_00188 5e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LCAHJLOB_00189 1.3e-292 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
LCAHJLOB_00190 9.4e-144 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LCAHJLOB_00191 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
LCAHJLOB_00192 0.0 ydaO E amino acid
LCAHJLOB_00193 1.8e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LCAHJLOB_00194 1.5e-36 ylqC L Belongs to the UPF0109 family
LCAHJLOB_00195 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LCAHJLOB_00197 1.7e-211 2.7.13.3 T protein histidine kinase activity
LCAHJLOB_00198 2.2e-123 agrA KT phosphorelay signal transduction system
LCAHJLOB_00199 1.7e-169 O protein import
LCAHJLOB_00200 6.2e-165 tehB 2.1.1.265 PQ tellurite resistance protein tehb
LCAHJLOB_00201 2.9e-17 yjdB S Domain of unknown function (DUF4767)
LCAHJLOB_00202 1.2e-102 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCAHJLOB_00204 2e-157 xth 3.1.11.2 L exodeoxyribonuclease III
LCAHJLOB_00205 1.1e-70 S QueT transporter
LCAHJLOB_00207 4.7e-169 yfjR K regulation of single-species biofilm formation
LCAHJLOB_00209 1.5e-183 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LCAHJLOB_00210 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LCAHJLOB_00211 2.8e-85 ccl S cog cog4708
LCAHJLOB_00212 2.2e-160 rbn E Belongs to the UPF0761 family
LCAHJLOB_00213 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
LCAHJLOB_00214 2.5e-231 ytoI K transcriptional regulator containing CBS domains
LCAHJLOB_00215 1.2e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
LCAHJLOB_00216 7.9e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCAHJLOB_00217 0.0 comEC S Competence protein ComEC
LCAHJLOB_00218 1.4e-90 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
LCAHJLOB_00219 1.1e-141 plsC 2.3.1.51 I Acyltransferase
LCAHJLOB_00220 1.3e-147 nodB3 G Polysaccharide deacetylase
LCAHJLOB_00221 3e-139 yabB 2.1.1.223 L Methyltransferase
LCAHJLOB_00222 4.3e-40 yazA L endonuclease containing a URI domain
LCAHJLOB_00225 1.7e-258 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LCAHJLOB_00226 1.8e-151 corA P CorA-like protein
LCAHJLOB_00227 9.6e-62 yjqA S Bacterial PH domain
LCAHJLOB_00228 1.8e-96 thiT S Thiamine transporter
LCAHJLOB_00229 2.9e-151 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LCAHJLOB_00230 1.8e-196 yjbB G Permeases of the major facilitator superfamily
LCAHJLOB_00231 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LCAHJLOB_00232 2.8e-117 ywaF S Integral membrane protein (intg_mem_TP0381)
LCAHJLOB_00233 1.5e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LCAHJLOB_00235 3.2e-145 L Integrase core domain protein
LCAHJLOB_00236 1.6e-123 L Helix-turn-helix domain
LCAHJLOB_00237 9.7e-228 L Transposase
LCAHJLOB_00238 0.0 U protein secretion
LCAHJLOB_00239 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LCAHJLOB_00240 7.1e-24
LCAHJLOB_00241 5e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
LCAHJLOB_00242 3.6e-236 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LCAHJLOB_00243 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
LCAHJLOB_00244 7.3e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LCAHJLOB_00245 6.8e-168 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
LCAHJLOB_00246 8.2e-171 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LCAHJLOB_00247 1.8e-140 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
LCAHJLOB_00248 1.7e-102 GBS0088 J protein conserved in bacteria
LCAHJLOB_00249 2e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCAHJLOB_00250 6.5e-137 E Alpha beta hydrolase
LCAHJLOB_00252 7.5e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
LCAHJLOB_00253 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LCAHJLOB_00254 2.7e-143 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LCAHJLOB_00255 1.7e-114 S VIT family
LCAHJLOB_00256 2.6e-135 deoD_1 2.4.2.3 F Phosphorylase superfamily
LCAHJLOB_00257 8.9e-20
LCAHJLOB_00258 1e-27 XK27_00085 K Transcriptional
LCAHJLOB_00259 1.4e-197 yceA S Belongs to the UPF0176 family
LCAHJLOB_00260 9e-49 S Protein conserved in bacteria
LCAHJLOB_00261 4.7e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LCAHJLOB_00262 2.1e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LCAHJLOB_00263 0.0 lmrA V abc transporter atp-binding protein
LCAHJLOB_00264 0.0 mdlB V abc transporter atp-binding protein
LCAHJLOB_00265 2.1e-272 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LCAHJLOB_00266 5.8e-106 abiGI K Transcriptional regulator, AbiEi antitoxin
LCAHJLOB_00267 4e-29 XK27_00530 M CHAP domain protein
LCAHJLOB_00268 2.1e-21 S Antitoxin component of a toxin-antitoxin (TA) module
LCAHJLOB_00270 6.5e-131 agrA KT Response regulator of the LytR AlgR family
LCAHJLOB_00271 1.6e-228 2.7.13.3 T GHKL domain
LCAHJLOB_00273 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LCAHJLOB_00274 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LCAHJLOB_00275 2.1e-211 V permease protein
LCAHJLOB_00276 3.4e-121 macB V ABC transporter, ATP-binding protein
LCAHJLOB_00277 8.8e-181 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LCAHJLOB_00278 2.3e-128 2.1.1.223 S Putative SAM-dependent methyltransferase
LCAHJLOB_00279 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
LCAHJLOB_00280 4.6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
LCAHJLOB_00281 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LCAHJLOB_00282 1.8e-221 pyrP F uracil Permease
LCAHJLOB_00283 1.8e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LCAHJLOB_00284 7.2e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LCAHJLOB_00285 1.4e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LCAHJLOB_00286 9e-167 fhuR K transcriptional regulator (lysR family)
LCAHJLOB_00288 2.8e-97
LCAHJLOB_00289 1.2e-57 V ABC-2 type transporter
LCAHJLOB_00290 7.8e-155 V AAA domain, putative AbiEii toxin, Type IV TA system
LCAHJLOB_00294 1.2e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LCAHJLOB_00295 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LCAHJLOB_00296 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
LCAHJLOB_00297 1.1e-251 cycA E permease
LCAHJLOB_00298 1.3e-38 ynzC S UPF0291 protein
LCAHJLOB_00299 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LCAHJLOB_00300 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LCAHJLOB_00301 1.6e-66 S Glutathione-dependent formaldehyde-activating
LCAHJLOB_00302 6.9e-202 S membrane
LCAHJLOB_00303 1.2e-211 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LCAHJLOB_00304 5e-293 nptA P COG1283 Na phosphate symporter
LCAHJLOB_00305 1.6e-114 3.4.17.14, 3.5.1.28 NU amidase activity
LCAHJLOB_00306 1.2e-75 S Bacterial inner membrane protein
LCAHJLOB_00307 1.3e-140 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
LCAHJLOB_00308 1.7e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
LCAHJLOB_00309 9.5e-53 glnB K Belongs to the P(II) protein family
LCAHJLOB_00310 5e-229 amt P Ammonium Transporter
LCAHJLOB_00311 6.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LCAHJLOB_00312 1.2e-54 yabA L Involved in initiation control of chromosome replication
LCAHJLOB_00313 1.4e-131 yaaT S stage 0 sporulation protein
LCAHJLOB_00314 3e-159 holB 2.7.7.7 L dna polymerase iii
LCAHJLOB_00315 6.5e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LCAHJLOB_00317 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LCAHJLOB_00318 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LCAHJLOB_00319 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LCAHJLOB_00320 1e-216 ftsW D Belongs to the SEDS family
LCAHJLOB_00321 8e-105 L COG1943 Transposase and inactivated derivatives
LCAHJLOB_00322 3.2e-145 L Integrase core domain protein
LCAHJLOB_00323 1e-60 L Helix-turn-helix domain
LCAHJLOB_00324 2.5e-297 O MreB/Mbl protein
LCAHJLOB_00326 5.8e-146 V Psort location CytoplasmicMembrane, score
LCAHJLOB_00329 8.9e-14
LCAHJLOB_00330 5.5e-226 dcuS 2.7.13.3 T protein histidine kinase activity
LCAHJLOB_00331 8.1e-236 2.7.13.3 T protein histidine kinase activity
LCAHJLOB_00332 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LCAHJLOB_00333 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LCAHJLOB_00334 6.2e-126 S Protein of unknown function (DUF554)
LCAHJLOB_00335 8.1e-134 ecsA_2 V abc transporter atp-binding protein
LCAHJLOB_00336 3.2e-284 XK27_00765
LCAHJLOB_00337 1e-224 L the current gene model (or a revised gene model) may contain a frame shift
LCAHJLOB_00338 1.7e-18 S Domain of unknown function (DUF4649)
LCAHJLOB_00339 2.4e-176 XK27_08835 S ABC transporter substrate binding protein
LCAHJLOB_00340 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
LCAHJLOB_00341 8.9e-136 XK27_08845 S abc transporter atp-binding protein
LCAHJLOB_00342 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LCAHJLOB_00343 5e-150 estA CE1 S Esterase
LCAHJLOB_00344 1.4e-125 XK27_08875 O Zinc-dependent metalloprotease
LCAHJLOB_00345 2.2e-18 XK27_08880
LCAHJLOB_00346 1e-75 fld C Flavodoxin
LCAHJLOB_00347 7.3e-278 clcA P Chloride transporter, ClC family
LCAHJLOB_00348 2.8e-39 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
LCAHJLOB_00349 3.8e-213 XK27_05110 P Chloride transporter ClC family
LCAHJLOB_00350 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LCAHJLOB_00353 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
LCAHJLOB_00354 1.3e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LCAHJLOB_00355 8e-88 ytsP 1.8.4.14 T GAF domain-containing protein
LCAHJLOB_00356 5.1e-301 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCAHJLOB_00357 1.7e-173 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LCAHJLOB_00358 2.3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LCAHJLOB_00359 1.4e-277 5.1.3.2 GM Psort location CytoplasmicMembrane, score
LCAHJLOB_00360 3e-146
LCAHJLOB_00361 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
LCAHJLOB_00362 1.2e-271 pelF GT4 M Domain of unknown function (DUF3492)
LCAHJLOB_00363 1.7e-183 pelG M Putative exopolysaccharide Exporter (EPS-E)
LCAHJLOB_00364 7.7e-223 cotH M CotH kinase protein
LCAHJLOB_00365 3e-96 P VTC domain
LCAHJLOB_00366 6e-83 S membrane
LCAHJLOB_00367 3.7e-135 G Domain of unknown function (DUF4832)
LCAHJLOB_00368 5.6e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LCAHJLOB_00370 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCAHJLOB_00371 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
LCAHJLOB_00372 1.2e-152 endA F DNA RNA non-specific endonuclease
LCAHJLOB_00373 2.9e-111 tcyB_2 P ABC transporter (permease)
LCAHJLOB_00374 1.9e-116 gltJ P ABC transporter (Permease
LCAHJLOB_00375 5.7e-144 peb1A ET Belongs to the bacterial solute-binding protein 3 family
LCAHJLOB_00376 7.9e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
LCAHJLOB_00377 1.1e-110 tcyB_2 P ABC transporter (permease)
LCAHJLOB_00378 1.9e-116 gltJ P ABC transporter (Permease
LCAHJLOB_00379 3e-145 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LCAHJLOB_00380 1.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
LCAHJLOB_00381 6.4e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LCAHJLOB_00382 4e-232 vicK 2.7.13.3 T Histidine kinase
LCAHJLOB_00383 2.7e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
LCAHJLOB_00384 1.5e-56 S Protein of unknown function (DUF454)
LCAHJLOB_00385 2.3e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
LCAHJLOB_00386 7.8e-146 yidA S hydrolases of the HAD superfamily
LCAHJLOB_00387 3.7e-138 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
LCAHJLOB_00388 5.1e-131 XK27_00120 2.4.2.3 F Phosphorylase superfamily
LCAHJLOB_00389 1.7e-66 ywiB S Domain of unknown function (DUF1934)
LCAHJLOB_00390 0.0 pacL 3.6.3.8 P cation transport ATPase
LCAHJLOB_00391 1.9e-130 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LCAHJLOB_00392 4e-153 yjjH S Calcineurin-like phosphoesterase
LCAHJLOB_00393 3.5e-205 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LCAHJLOB_00394 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LCAHJLOB_00395 3.2e-124 ftsE D cell division ATP-binding protein FtsE
LCAHJLOB_00396 2.1e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LCAHJLOB_00397 4.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
LCAHJLOB_00398 1.2e-174 yubA S permease
LCAHJLOB_00399 7.8e-222 G COG0457 FOG TPR repeat
LCAHJLOB_00400 3.3e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LCAHJLOB_00401 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LCAHJLOB_00402 2.2e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LCAHJLOB_00403 9.6e-86 ebsA S Family of unknown function (DUF5322)
LCAHJLOB_00404 5.5e-17 M LysM domain
LCAHJLOB_00405 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LCAHJLOB_00406 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LCAHJLOB_00407 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LCAHJLOB_00408 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LCAHJLOB_00409 5.5e-75 XK27_03610 K Gnat family
LCAHJLOB_00410 1.5e-89 yybC
LCAHJLOB_00411 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LCAHJLOB_00412 2e-274 pepV 3.5.1.18 E Dipeptidase
LCAHJLOB_00413 5.5e-109 ung2 3.2.2.27 L Uracil-DNA glycosylase
LCAHJLOB_00414 2.9e-227 V Glucan-binding protein C
LCAHJLOB_00415 1.3e-252 V Glucan-binding protein C
LCAHJLOB_00416 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LCAHJLOB_00417 1.4e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LCAHJLOB_00418 2.7e-86 S Protein of unknown function (DUF1697)
LCAHJLOB_00419 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LCAHJLOB_00420 3.2e-50 S LemA family
LCAHJLOB_00421 4.5e-177 clcA_2 P Chloride transporter, ClC family
LCAHJLOB_00422 5.3e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
LCAHJLOB_00423 3.7e-131 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
LCAHJLOB_00424 1.2e-248 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
LCAHJLOB_00425 2.6e-132 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
LCAHJLOB_00426 3.5e-110 cps4C M biosynthesis protein
LCAHJLOB_00427 1.3e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
LCAHJLOB_00428 1.8e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
LCAHJLOB_00429 4.8e-221 rgpAc GT4 M group 1 family protein
LCAHJLOB_00430 6.8e-212 wcoF M Glycosyltransferase, group 1 family protein
LCAHJLOB_00431 2e-120 Z012_10770 M Domain of unknown function (DUF1919)
LCAHJLOB_00432 8.2e-166 M Glycosyltransferase, group 2 family protein
LCAHJLOB_00433 3.9e-155 M Glycosyltransferase like family 2
LCAHJLOB_00434 7.5e-174
LCAHJLOB_00435 7.5e-245 epsU S Polysaccharide biosynthesis protein
LCAHJLOB_00436 4.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
LCAHJLOB_00437 1.4e-173 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
LCAHJLOB_00438 1e-185 wbbI M transferase activity, transferring glycosyl groups
LCAHJLOB_00439 9.7e-228 L Transposase
LCAHJLOB_00440 1.3e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LCAHJLOB_00441 1.5e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
LCAHJLOB_00442 7.4e-80 hmpT S cog cog4720
LCAHJLOB_00443 6.3e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LCAHJLOB_00444 1.6e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LCAHJLOB_00445 2e-46 yhaI S Protein of unknown function (DUF805)
LCAHJLOB_00446 9.1e-39 yhaI J Protein of unknown function (DUF805)
LCAHJLOB_00447 3.5e-46 yhaI J Protein of unknown function (DUF805)
LCAHJLOB_00450 7.7e-98
LCAHJLOB_00451 3.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LCAHJLOB_00452 2.4e-45 ftsL D cell division protein FtsL
LCAHJLOB_00453 0.0 ftsI 3.4.16.4 M penicillin-binding protein
LCAHJLOB_00454 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LCAHJLOB_00455 1e-219 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LCAHJLOB_00456 5e-151 V ATPases associated with a variety of cellular activities
LCAHJLOB_00457 2.5e-122
LCAHJLOB_00458 4.1e-130 KT COG3279 Response regulator of the LytR AlgR family
LCAHJLOB_00459 7.9e-217 T GHKL domain
LCAHJLOB_00461 7.9e-252 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LCAHJLOB_00462 6.9e-61 yutD J protein conserved in bacteria
LCAHJLOB_00463 6.2e-221 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LCAHJLOB_00464 3.7e-88 XK27_09885 V Glycopeptide antibiotics resistance protein
LCAHJLOB_00466 0.0 mdlA V abc transporter atp-binding protein
LCAHJLOB_00467 0.0 mdlB V abc transporter atp-binding protein
LCAHJLOB_00474 5.9e-43 spiA K sequence-specific DNA binding
LCAHJLOB_00476 6.7e-07
LCAHJLOB_00477 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LCAHJLOB_00478 5.6e-150 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
LCAHJLOB_00479 1.5e-94 V CAAX protease self-immunity
LCAHJLOB_00480 4.7e-137 cppA E CppA N-terminal
LCAHJLOB_00481 4.3e-172 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
LCAHJLOB_00483 3.4e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LCAHJLOB_00484 2.3e-142 cah 4.2.1.1 P carbonic anhydrase
LCAHJLOB_00485 0.0 pflB 2.3.1.54 C formate acetyltransferase'
LCAHJLOB_00486 1e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCAHJLOB_00487 3.6e-35
LCAHJLOB_00488 4.7e-13
LCAHJLOB_00489 5.2e-33 S Domain of unknown function (DUF4176)
LCAHJLOB_00490 2.6e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LCAHJLOB_00491 1.4e-162 yxeN P ABC transporter (Permease
LCAHJLOB_00492 7.9e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
LCAHJLOB_00493 5e-10 S Protein of unknown function (DUF4059)
LCAHJLOB_00494 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LCAHJLOB_00495 9.6e-92 rsmD 2.1.1.171 L Methyltransferase
LCAHJLOB_00496 4.3e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LCAHJLOB_00497 8.4e-188 ylbL T Belongs to the peptidase S16 family
LCAHJLOB_00498 7.9e-182 yhcC S radical SAM protein
LCAHJLOB_00499 1.4e-93 ytqB 2.1.1.176 J (SAM)-dependent
LCAHJLOB_00501 0.0 yjcE P NhaP-type Na H and K H antiporters
LCAHJLOB_00502 1e-24
LCAHJLOB_00504 1.5e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
LCAHJLOB_00505 2.4e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
LCAHJLOB_00506 4.8e-09 MU outer membrane autotransporter barrel domain protein
LCAHJLOB_00507 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCAHJLOB_00509 1.2e-74 XK27_03180 T universal stress protein
LCAHJLOB_00510 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
LCAHJLOB_00511 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LCAHJLOB_00512 4.4e-100 pncA Q isochorismatase
LCAHJLOB_00513 1.1e-291 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LCAHJLOB_00514 3.3e-217 M lipopolysaccharide 3-alpha-galactosyltransferase activity
LCAHJLOB_00515 2.4e-156 H COG0463 Glycosyltransferases involved in cell wall biogenesis
LCAHJLOB_00516 1.2e-188 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
LCAHJLOB_00517 3.4e-232 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
LCAHJLOB_00518 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCAHJLOB_00519 5.5e-267 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LCAHJLOB_00520 1.1e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCAHJLOB_00522 1.2e-282 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LCAHJLOB_00523 3.2e-29 S PQ loop repeat
LCAHJLOB_00524 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
LCAHJLOB_00525 1.4e-276 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
LCAHJLOB_00526 1.7e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
LCAHJLOB_00527 5e-58
LCAHJLOB_00528 1.8e-216 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LCAHJLOB_00529 1.8e-60
LCAHJLOB_00530 1.5e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
LCAHJLOB_00531 7e-151 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LCAHJLOB_00532 5.1e-98 yqeG S hydrolase of the HAD superfamily
LCAHJLOB_00533 5.4e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LCAHJLOB_00534 7.7e-49 yhbY J RNA-binding protein
LCAHJLOB_00535 1e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LCAHJLOB_00536 2.4e-104 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LCAHJLOB_00537 3e-87 entB 3.5.1.19 Q Isochorismatase family
LCAHJLOB_00538 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LCAHJLOB_00539 3.8e-139 yqeM Q Methyltransferase domain protein
LCAHJLOB_00540 3.4e-197 ylbM S Belongs to the UPF0348 family
LCAHJLOB_00541 2.9e-38 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
LCAHJLOB_00542 1e-43 yoeB S Addiction module toxin, Txe YoeB family
LCAHJLOB_00545 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
LCAHJLOB_00546 4.1e-43
LCAHJLOB_00548 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LCAHJLOB_00549 1.9e-130 ecsA V abc transporter atp-binding protein
LCAHJLOB_00550 2.5e-173 ecsB U Bacterial ABC transporter protein EcsB
LCAHJLOB_00551 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
LCAHJLOB_00552 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LCAHJLOB_00554 1.4e-220 ytfP S Flavoprotein
LCAHJLOB_00555 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LCAHJLOB_00556 9.6e-64 XK27_02560 S cog cog2151
LCAHJLOB_00557 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
LCAHJLOB_00558 5.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
LCAHJLOB_00559 2.5e-127 K transcriptional regulator, MerR family
LCAHJLOB_00560 0.0 V ABC transporter (Permease
LCAHJLOB_00561 1.9e-124 V abc transporter atp-binding protein
LCAHJLOB_00563 5.6e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LCAHJLOB_00564 2.7e-51
LCAHJLOB_00565 1.9e-44
LCAHJLOB_00566 1.2e-78
LCAHJLOB_00568 0.0
LCAHJLOB_00569 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
LCAHJLOB_00570 1.1e-150 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
LCAHJLOB_00571 4.4e-162 T Diguanylate cyclase
LCAHJLOB_00572 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LCAHJLOB_00573 2.2e-60 fruR K transcriptional
LCAHJLOB_00574 6.7e-26 L Transposase
LCAHJLOB_00575 2.2e-45
LCAHJLOB_00576 0.0 ctpE P E1-E2 ATPase
LCAHJLOB_00577 1.1e-57
LCAHJLOB_00578 2.1e-19 S Bacteriocin (Lactococcin_972)
LCAHJLOB_00579 0.0 S bacteriocin-associated integral membrane protein
LCAHJLOB_00580 3.5e-120 yujD V lipoprotein transporter activity
LCAHJLOB_00581 8.9e-41 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
LCAHJLOB_00582 1.2e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LCAHJLOB_00583 4e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
LCAHJLOB_00584 1.3e-177 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LCAHJLOB_00585 7.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LCAHJLOB_00586 6.1e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
LCAHJLOB_00587 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LCAHJLOB_00588 3.3e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LCAHJLOB_00590 5e-162 EGP Major facilitator Superfamily
LCAHJLOB_00591 6.1e-73 copY K negative regulation of transcription, DNA-templated
LCAHJLOB_00592 0.0 copA 3.6.3.54 P P-type ATPase
LCAHJLOB_00593 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
LCAHJLOB_00594 1.5e-34 K Transcriptional regulator C-terminal region
LCAHJLOB_00595 2.2e-83 V ABC transporter
LCAHJLOB_00596 5.6e-56
LCAHJLOB_00597 3e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LCAHJLOB_00598 3.9e-114 papP P ABC transporter (Permease
LCAHJLOB_00599 3e-106 P ABC transporter (Permease
LCAHJLOB_00600 3.8e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
LCAHJLOB_00601 9.7e-155 cjaA ET ABC transporter substrate-binding protein
LCAHJLOB_00605 1.6e-123 L Helix-turn-helix domain
LCAHJLOB_00606 1.6e-123 L Helix-turn-helix domain
LCAHJLOB_00607 0.0 S the current gene model (or a revised gene model) may contain a frame shift
LCAHJLOB_00608 8.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LCAHJLOB_00609 4.1e-121 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LCAHJLOB_00610 1.1e-212 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCAHJLOB_00611 2.5e-245 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
LCAHJLOB_00612 6.5e-182 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
LCAHJLOB_00613 9e-153 rssA S Phospholipase, patatin family
LCAHJLOB_00614 7.2e-99 estA E Lysophospholipase L1 and related esterases
LCAHJLOB_00615 2.3e-279 S unusual protein kinase
LCAHJLOB_00616 2.1e-37 S granule-associated protein
LCAHJLOB_00617 5.4e-283 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LCAHJLOB_00618 1.4e-196 S hmm pf01594
LCAHJLOB_00619 2.8e-108 G Belongs to the phosphoglycerate mutase family
LCAHJLOB_00620 5.4e-107 G Belongs to the phosphoglycerate mutase family
LCAHJLOB_00621 6.9e-107 pgm G Belongs to the phosphoglycerate mutase family
LCAHJLOB_00622 2.9e-148 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LCAHJLOB_00626 5.2e-44
LCAHJLOB_00629 1.7e-130 clpB O C-terminal, D2-small domain, of ClpB protein
LCAHJLOB_00631 1.8e-45
LCAHJLOB_00632 8.9e-54 I mechanosensitive ion channel activity
LCAHJLOB_00633 1.9e-96 fic D nucleotidyltransferase activity
LCAHJLOB_00634 1.6e-25
LCAHJLOB_00636 6e-29
LCAHJLOB_00637 1.9e-113 U AAA-like domain
LCAHJLOB_00639 2.1e-14
LCAHJLOB_00641 4.1e-42 xisC L viral genome integration into host DNA
LCAHJLOB_00644 1.8e-260 hsdM 2.1.1.72 V N-6 DNA Methylase
LCAHJLOB_00645 1e-176 S Virulence protein RhuM family
LCAHJLOB_00646 7.3e-140 hsdS 3.1.21.3 V COG0732 Restriction endonuclease S subunits
LCAHJLOB_00647 9.5e-81 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
LCAHJLOB_00648 1.3e-218 prrC V Anti-codon nuclease
LCAHJLOB_00649 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
LCAHJLOB_00650 2.3e-30
LCAHJLOB_00651 8e-07
LCAHJLOB_00654 6.3e-81 S Protein conserved in bacteria
LCAHJLOB_00658 1.9e-14 dnaX 2.4.99.16, 2.7.7.7 GH13 D cell septum assembly
LCAHJLOB_00659 7.1e-129 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LCAHJLOB_00660 3.2e-30
LCAHJLOB_00661 1.2e-20
LCAHJLOB_00662 1e-60 L Transposase
LCAHJLOB_00663 6.2e-194
LCAHJLOB_00664 4.9e-95
LCAHJLOB_00665 2.1e-25 int L DNA integration
LCAHJLOB_00666 1.1e-81 2.3.1.128 J Acetyltransferase GNAT Family
LCAHJLOB_00668 9e-77
LCAHJLOB_00669 5.3e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCAHJLOB_00670 8.9e-54
LCAHJLOB_00672 1.1e-102 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
LCAHJLOB_00676 9.2e-41
LCAHJLOB_00677 3.4e-31 L Helix-turn-helix domain
LCAHJLOB_00678 1.6e-61 L COG1943 Transposase and inactivated derivatives
LCAHJLOB_00680 1.5e-185 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LCAHJLOB_00681 1.5e-218 Q Polyketide synthase of type I
LCAHJLOB_00682 3.7e-103 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LCAHJLOB_00684 4.6e-80 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LCAHJLOB_00685 1.8e-244 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LCAHJLOB_00686 3.9e-83 bacE_1 EGP Transmembrane secretion effector
LCAHJLOB_00687 7.9e-51 L Transposase
LCAHJLOB_00688 6e-27 F phosphoribosylamine-glycine ligase activity
LCAHJLOB_00689 1.9e-18 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
LCAHJLOB_00691 1.2e-173 XK27_00515 D Glucan-binding protein C
LCAHJLOB_00692 6.4e-101 V Abi-like protein
LCAHJLOB_00693 4.2e-182 XK27_00530 S CHAP domain
LCAHJLOB_00694 1.7e-154 hpaIIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
LCAHJLOB_00696 8.8e-46 repA S Replication initiator protein A
LCAHJLOB_00697 1.2e-17 L Transposase
LCAHJLOB_00698 2.7e-50 L Transposase IS116 IS110 IS902
LCAHJLOB_00701 2.2e-20 XK27_10050 K Peptidase S24-like
LCAHJLOB_00703 1.9e-20 L overlaps another CDS with the same product name
LCAHJLOB_00704 7e-69 S ABC-2 family transporter protein
LCAHJLOB_00705 3.4e-79 S ABC-2 family transporter protein
LCAHJLOB_00706 1.7e-117 bcrA V abc transporter atp-binding protein
LCAHJLOB_00707 2.3e-210 V Lantibiotic transport processing ATP-binding protein
LCAHJLOB_00708 2.7e-262 lcnDR2 V Domain of unknown function (DUF4135)
LCAHJLOB_00710 8.3e-96 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LCAHJLOB_00711 3.1e-163 T PhoQ Sensor
LCAHJLOB_00712 4.5e-63 L Transposase IS116 IS110 IS902
LCAHJLOB_00713 5.1e-41 L transposase IS116 IS110 IS902 family
LCAHJLOB_00714 3e-102 salR K helix_turn_helix, Lux Regulon
LCAHJLOB_00715 2.1e-240 salK 2.7.13.3 T Histidine kinase
LCAHJLOB_00716 2.1e-290 V FtsX-like permease family
LCAHJLOB_00717 4.6e-121 V ABC transporter
LCAHJLOB_00718 0.0 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LCAHJLOB_00719 0.0 salB V Lanthionine synthetase C-like protein
LCAHJLOB_00721 0.0 XK27_00500 L the current gene model (or a revised gene model) may contain a
LCAHJLOB_00723 1.1e-55 S PcfJ-like protein
LCAHJLOB_00724 5.8e-10 S PcfK-like protein
LCAHJLOB_00725 1.1e-38 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCAHJLOB_00727 2.5e-17
LCAHJLOB_00728 9.1e-75 S Region found in RelA / SpoT proteins
LCAHJLOB_00729 2.2e-28 dnaG L DNA primase activity
LCAHJLOB_00730 2.8e-26 soj D ATPases involved in chromosome partitioning
LCAHJLOB_00732 2.8e-08 L Psort location Cytoplasmic, score 8.96
LCAHJLOB_00733 3.3e-21 xerS L Belongs to the 'phage' integrase family
LCAHJLOB_00734 2.1e-51 spd F DNA RNA non-specific endonuclease
LCAHJLOB_00735 1.2e-49 L Helix-turn-helix domain
LCAHJLOB_00736 3.2e-145 L Integrase core domain protein
LCAHJLOB_00737 6.7e-224 2.7.13.3 T protein histidine kinase activity
LCAHJLOB_00738 7.7e-201 hpk9 2.7.13.3 T protein histidine kinase activity
LCAHJLOB_00739 5.6e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
LCAHJLOB_00740 4.1e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LCAHJLOB_00741 1.8e-211 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LCAHJLOB_00742 0.0 lpdA 1.8.1.4 C Dehydrogenase
LCAHJLOB_00743 0.0 3.5.1.28 NU amidase activity
LCAHJLOB_00744 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
LCAHJLOB_00745 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LCAHJLOB_00746 2.4e-145 ycdO P periplasmic lipoprotein involved in iron transport
LCAHJLOB_00747 6.2e-232 ycdB P peroxidase
LCAHJLOB_00748 2.2e-288 ywbL P COG0672 High-affinity Fe2 Pb2 permease
LCAHJLOB_00749 3e-117 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LCAHJLOB_00750 9.5e-23 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LCAHJLOB_00751 1.4e-212 msmX P Belongs to the ABC transporter superfamily
LCAHJLOB_00752 9.8e-152 malG P ABC transporter (Permease
LCAHJLOB_00753 5.7e-250 malF P ABC transporter (Permease
LCAHJLOB_00754 6.2e-227 malX G ABC transporter
LCAHJLOB_00755 2.1e-156 malR K Transcriptional regulator
LCAHJLOB_00756 3.6e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
LCAHJLOB_00757 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LCAHJLOB_00758 3e-39
LCAHJLOB_00759 2.6e-183 lplA 6.3.1.20 H Lipoate-protein ligase
LCAHJLOB_00760 1e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
LCAHJLOB_00761 0.0 pepN 3.4.11.2 E aminopeptidase
LCAHJLOB_00762 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
LCAHJLOB_00763 8.6e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LCAHJLOB_00764 3.4e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LCAHJLOB_00765 2.6e-155 pstA P phosphate transport system permease
LCAHJLOB_00766 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
LCAHJLOB_00767 4.9e-154 pstS P phosphate
LCAHJLOB_00768 7.7e-244 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
LCAHJLOB_00769 3.6e-140 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
LCAHJLOB_00770 1e-44 yktA S Belongs to the UPF0223 family
LCAHJLOB_00771 7.9e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LCAHJLOB_00772 3.3e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LCAHJLOB_00773 2.8e-146 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LCAHJLOB_00774 1.4e-237 XK27_04775 S hemerythrin HHE cation binding domain
LCAHJLOB_00775 6.8e-34 M1-755 P Hemerythrin HHE cation binding domain protein
LCAHJLOB_00776 9e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
LCAHJLOB_00777 1.2e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LCAHJLOB_00778 2.3e-136 S haloacid dehalogenase-like hydrolase
LCAHJLOB_00779 2.3e-240 metY 2.5.1.49 E o-acetylhomoserine
LCAHJLOB_00780 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LCAHJLOB_00781 5.3e-240 agcS E (Alanine) symporter
LCAHJLOB_00782 2e-242 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LCAHJLOB_00783 3.8e-171 bglC K Transcriptional regulator
LCAHJLOB_00784 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
LCAHJLOB_00785 9.3e-81 yecS P ABC transporter (Permease
LCAHJLOB_00786 6e-149 yckB ET Belongs to the bacterial solute-binding protein 3 family
LCAHJLOB_00787 1.4e-230 nylA 3.5.1.4 J Belongs to the amidase family
LCAHJLOB_00788 1.7e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LCAHJLOB_00789 5.9e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LCAHJLOB_00792 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LCAHJLOB_00793 3.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LCAHJLOB_00794 4.4e-92 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
LCAHJLOB_00795 4.2e-136 S TraX protein
LCAHJLOB_00796 1.2e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LCAHJLOB_00797 4e-276 S Psort location CytoplasmicMembrane, score
LCAHJLOB_00798 3.1e-232 dinF V Mate efflux family protein
LCAHJLOB_00799 4.1e-178 yclQ P ABC-type enterochelin transport system, periplasmic component
LCAHJLOB_00800 0.0 V Type III restriction enzyme, res subunit
LCAHJLOB_00801 1.1e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
LCAHJLOB_00802 5.9e-241 S the current gene model (or a revised gene model) may contain a frame shift
LCAHJLOB_00803 3.4e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
LCAHJLOB_00804 4.2e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LCAHJLOB_00805 1.9e-156 czcD P cation diffusion facilitator family transporter
LCAHJLOB_00806 2.7e-94 K Transcriptional regulator, TetR family
LCAHJLOB_00807 8.7e-65 S Protein of unknown function with HXXEE motif
LCAHJLOB_00808 4.5e-161 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
LCAHJLOB_00809 4.9e-23 3.1.21.3 V type I restriction modification DNA specificity domain
LCAHJLOB_00810 1.3e-148 cbiO2 P ABC transporter, ATP-binding protein
LCAHJLOB_00811 2.3e-156 P ATPase activity
LCAHJLOB_00812 2e-117 cbiQ P cobalt transport
LCAHJLOB_00813 3.7e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
LCAHJLOB_00814 3.5e-138 S Phenazine biosynthesis protein
LCAHJLOB_00815 8.3e-266 proWX P ABC transporter
LCAHJLOB_00816 8.3e-123 proV E abc transporter atp-binding protein
LCAHJLOB_00817 2.1e-150 C alcohol dehydrogenase
LCAHJLOB_00818 3.2e-64 mgrA K Transcriptional regulator, MarR family
LCAHJLOB_00819 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
LCAHJLOB_00820 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LCAHJLOB_00823 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LCAHJLOB_00825 8.2e-137 IQ Acetoin reductase
LCAHJLOB_00826 2.9e-42 pspE P Rhodanese-like protein
LCAHJLOB_00827 1.3e-70 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LCAHJLOB_00828 8e-221 XK27_05470 E Methionine synthase
LCAHJLOB_00829 1.5e-255 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LCAHJLOB_00830 2.6e-242 T PhoQ Sensor
LCAHJLOB_00831 1e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LCAHJLOB_00832 2e-144 S TraX protein
LCAHJLOB_00833 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCAHJLOB_00834 3e-156 dprA LU DNA protecting protein DprA
LCAHJLOB_00835 1.8e-162 GK ROK family
LCAHJLOB_00836 5.5e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCAHJLOB_00837 7.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LCAHJLOB_00838 4.8e-128 K DNA-binding helix-turn-helix protein
LCAHJLOB_00839 9.5e-89 niaR S small molecule binding protein (contains 3H domain)
LCAHJLOB_00840 5.3e-87
LCAHJLOB_00841 1.1e-273 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LCAHJLOB_00842 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LCAHJLOB_00843 1.9e-124 gntR1 K transcriptional
LCAHJLOB_00844 1.8e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LCAHJLOB_00845 2.2e-97 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LCAHJLOB_00846 1.6e-188 adhP 1.1.1.1 C alcohol dehydrogenase
LCAHJLOB_00847 1.5e-43
LCAHJLOB_00848 6.2e-53
LCAHJLOB_00849 2.9e-265 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCAHJLOB_00850 6.7e-156 aatB ET ABC transporter substrate-binding protein
LCAHJLOB_00851 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
LCAHJLOB_00852 3.1e-105 artQ P ABC transporter (Permease
LCAHJLOB_00853 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
LCAHJLOB_00854 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LCAHJLOB_00855 3.8e-165 cpsY K Transcriptional regulator
LCAHJLOB_00856 7.9e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
LCAHJLOB_00857 1e-166 yeiH S Membrane
LCAHJLOB_00859 8.9e-10
LCAHJLOB_00860 5.2e-284 adcA P Belongs to the bacterial solute-binding protein 9 family
LCAHJLOB_00861 1.3e-143 XK27_10720 D peptidase activity
LCAHJLOB_00862 3.6e-276 pepD E Dipeptidase
LCAHJLOB_00863 2.2e-160 whiA K May be required for sporulation
LCAHJLOB_00864 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LCAHJLOB_00865 2.2e-162 rapZ S Displays ATPase and GTPase activities
LCAHJLOB_00866 7.7e-135 yejC S cyclic nucleotide-binding protein
LCAHJLOB_00867 2.7e-200 D nuclear chromosome segregation
LCAHJLOB_00868 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
LCAHJLOB_00869 1.5e-132 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LCAHJLOB_00870 8.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
LCAHJLOB_00871 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LCAHJLOB_00872 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
LCAHJLOB_00873 1.1e-199 pmrB EGP Major facilitator Superfamily
LCAHJLOB_00874 8.2e-19
LCAHJLOB_00875 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LCAHJLOB_00876 7e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LCAHJLOB_00877 1.1e-81 ypmB S Protein conserved in bacteria
LCAHJLOB_00878 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LCAHJLOB_00879 8.9e-113 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LCAHJLOB_00880 2.3e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
LCAHJLOB_00881 8.6e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
LCAHJLOB_00882 3.5e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LCAHJLOB_00883 1.8e-190 tcsA S membrane
LCAHJLOB_00884 1.5e-65 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LCAHJLOB_00885 7.9e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LCAHJLOB_00886 4.9e-227 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
LCAHJLOB_00887 5.9e-103 rsmC 2.1.1.172 J Methyltransferase small domain protein
LCAHJLOB_00888 2.6e-169 coaA 2.7.1.33 F Pantothenic acid kinase
LCAHJLOB_00889 2.3e-29 rpsT J Binds directly to 16S ribosomal RNA
LCAHJLOB_00890 3.8e-233 T PhoQ Sensor
LCAHJLOB_00891 2.1e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LCAHJLOB_00892 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LCAHJLOB_00893 3.1e-111 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
LCAHJLOB_00894 2.4e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCAHJLOB_00895 7.8e-92 panT S ECF transporter, substrate-specific component
LCAHJLOB_00896 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LCAHJLOB_00897 1.6e-165 metF 1.5.1.20 E reductase
LCAHJLOB_00898 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LCAHJLOB_00900 1.7e-307 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
LCAHJLOB_00901 2.7e-112 apt 2.4.2.22, 2.4.2.7 F TRSP domain C terminus to PRTase_2
LCAHJLOB_00902 9.8e-144 stiP J Phosphoribosyl transferase (PRTase)
LCAHJLOB_00903 3.1e-199 yceG S Putative component of 'biosynthetic module'
LCAHJLOB_00904 9.5e-166 yceH P Belongs to the TelA family
LCAHJLOB_00905 1.2e-90 T proteins involved in stress response, homologs of TerZ and
LCAHJLOB_00906 6.8e-77 T proteins involved in stress response, homologs of TerZ and
LCAHJLOB_00907 1.8e-89 T proteins involved in stress response, homologs of TerZ and
LCAHJLOB_00908 0.0 3.6.3.8 P cation transport ATPase
LCAHJLOB_00909 5.3e-75 3.1.3.12 S hydrolases of the HAD superfamily
LCAHJLOB_00910 9.4e-91 G Citrate lyase beta subunit
LCAHJLOB_00911 4.5e-233 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LCAHJLOB_00912 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LCAHJLOB_00913 8.1e-235 dltB M Membrane protein involved in D-alanine export
LCAHJLOB_00914 2.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LCAHJLOB_00915 0.0 XK27_10035 V abc transporter atp-binding protein
LCAHJLOB_00916 1.9e-290 yfiB1 V abc transporter atp-binding protein
LCAHJLOB_00917 3.2e-99 pvaA M lytic transglycosylase activity
LCAHJLOB_00918 2.7e-177 ndpA S 37-kD nucleoid-associated bacterial protein
LCAHJLOB_00919 6.7e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LCAHJLOB_00920 3.6e-103 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LCAHJLOB_00921 2.2e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LCAHJLOB_00922 1.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LCAHJLOB_00923 3e-110 tdk 2.7.1.21 F thymidine kinase
LCAHJLOB_00924 6.9e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LCAHJLOB_00925 2.4e-152 gst O Glutathione S-transferase
LCAHJLOB_00926 6e-174 nrnA 3.1.13.3, 3.1.3.7 S domain protein
LCAHJLOB_00927 6.4e-168 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LCAHJLOB_00928 4.4e-45 rpmE2 J 50S ribosomal protein L31
LCAHJLOB_00929 2.4e-113 mntH P Mn2 and Fe2 transporters of the NRAMP family
LCAHJLOB_00930 1.2e-89 mntH P Mn2 and Fe2 transporters of the NRAMP family
LCAHJLOB_00931 6.4e-163 ypuA S secreted protein
LCAHJLOB_00932 8.2e-72 yaeR E COG0346 Lactoylglutathione lyase and related lyases
LCAHJLOB_00933 1e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
LCAHJLOB_00934 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCAHJLOB_00935 5.9e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LCAHJLOB_00936 3.9e-254 noxE P NADH oxidase
LCAHJLOB_00937 3.3e-294 yfmM S abc transporter atp-binding protein
LCAHJLOB_00938 2e-78 XK27_01265 S ECF-type riboflavin transporter, S component
LCAHJLOB_00939 2.4e-145 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
LCAHJLOB_00940 1.6e-83 S ECF-type riboflavin transporter, S component
LCAHJLOB_00942 2.6e-236 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LCAHJLOB_00943 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
LCAHJLOB_00945 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LCAHJLOB_00946 8.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LCAHJLOB_00947 3.3e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LCAHJLOB_00948 1.8e-22 WQ51_00220 K Helix-turn-helix domain
LCAHJLOB_00949 5.3e-90 S Protein of unknown function (DUF3278)
LCAHJLOB_00950 0.0 smc D Required for chromosome condensation and partitioning
LCAHJLOB_00951 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LCAHJLOB_00952 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LCAHJLOB_00953 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LCAHJLOB_00954 8.8e-124 alkD L DNA alkylation repair enzyme
LCAHJLOB_00955 5.7e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCAHJLOB_00956 5.2e-87 pat 2.3.1.183 M acetyltransferase
LCAHJLOB_00957 4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCAHJLOB_00958 2.6e-152 L PFAM Integrase catalytic region
LCAHJLOB_00959 7.4e-278 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LCAHJLOB_00960 2.6e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LCAHJLOB_00961 1.5e-36 L RePlication protein
LCAHJLOB_00962 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LCAHJLOB_00963 1.7e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
LCAHJLOB_00964 1.8e-119 sdaAB 4.3.1.17 E L-serine dehydratase
LCAHJLOB_00965 3.4e-147 sdaAA 4.3.1.17 E L-serine dehydratase
LCAHJLOB_00966 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
LCAHJLOB_00967 2.3e-162 yjlA EG membrane
LCAHJLOB_00968 3.6e-80 3.4.21.89 S RDD family
LCAHJLOB_00969 1.7e-141 K sequence-specific DNA binding
LCAHJLOB_00970 2.9e-151 V ABC transporter, ATP-binding protein
LCAHJLOB_00971 1.9e-95 S ABC-2 family transporter protein
LCAHJLOB_00972 2e-145 K sequence-specific DNA binding
LCAHJLOB_00973 1.5e-27
LCAHJLOB_00974 2e-77 yfiQ K Acetyltransferase (GNAT) domain
LCAHJLOB_00975 6.6e-142 S ABC-2 family transporter protein
LCAHJLOB_00976 2.4e-142 S ABC-2 family transporter protein
LCAHJLOB_00977 7.2e-186 S abc transporter atp-binding protein
LCAHJLOB_00980 4.3e-85 yfjR K regulation of single-species biofilm formation
LCAHJLOB_00981 2.1e-126 S Protein of unknown function DUF262
LCAHJLOB_00982 3.2e-209 S Protein of unknown function DUF262
LCAHJLOB_00983 3.3e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LCAHJLOB_00984 3.2e-187 desK 2.7.13.3 T Histidine kinase
LCAHJLOB_00985 1.5e-132 yvfS V ABC-2 type transporter
LCAHJLOB_00986 1.1e-156 XK27_09825 V 'abc transporter, ATP-binding protein
LCAHJLOB_00989 5.1e-165 yocS S Transporter
LCAHJLOB_00990 5.2e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
LCAHJLOB_00991 2.6e-116 yvfS V Transporter
LCAHJLOB_00992 6.9e-156 XK27_09825 V abc transporter atp-binding protein
LCAHJLOB_00993 2e-14 liaI KT membrane
LCAHJLOB_00994 4e-31 liaI KT membrane
LCAHJLOB_00995 6.1e-93 XK27_05000 S metal cluster binding
LCAHJLOB_00996 0.0 V ABC transporter (permease)
LCAHJLOB_00997 2.2e-134 macB2 V ABC transporter, ATP-binding protein
LCAHJLOB_00998 2.5e-162 T Histidine kinase
LCAHJLOB_00999 2.7e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LCAHJLOB_01000 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LCAHJLOB_01001 2.5e-223 pbuX F xanthine permease
LCAHJLOB_01002 2.2e-277 V (ABC) transporter
LCAHJLOB_01003 6.4e-143 K sequence-specific DNA binding
LCAHJLOB_01004 3e-243 norM V Multidrug efflux pump
LCAHJLOB_01006 1.2e-174 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCAHJLOB_01007 1.7e-230 brnQ E Component of the transport system for branched-chain amino acids
LCAHJLOB_01008 8.7e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
LCAHJLOB_01009 2e-58 S Protein of unknown function (DUF3290)
LCAHJLOB_01010 6e-101 S Protein of unknown function (DUF421)
LCAHJLOB_01011 5.9e-15 csbD K CsbD-like
LCAHJLOB_01012 3.2e-103 S Carbohydrate-binding domain-containing protein Cthe_2159
LCAHJLOB_01013 6.8e-51 XK27_01300 P Protein conserved in bacteria
LCAHJLOB_01014 1.4e-216 yfnA E amino acid
LCAHJLOB_01015 0.0 S dextransucrase activity
LCAHJLOB_01016 6.2e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
LCAHJLOB_01017 2.1e-112 yxeN P ABC transporter, permease protein
LCAHJLOB_01018 1e-109 ytmL P ABC transporter (Permease
LCAHJLOB_01019 1.8e-164 ET ABC transporter substrate-binding protein
LCAHJLOB_01020 3.6e-177 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
LCAHJLOB_01021 4.6e-85 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LCAHJLOB_01022 2e-42 S Sugar efflux transporter for intercellular exchange
LCAHJLOB_01023 6.1e-205 P FtsX-like permease family
LCAHJLOB_01024 3.5e-123 V abc transporter atp-binding protein
LCAHJLOB_01025 9.6e-98 K WHG domain
LCAHJLOB_01026 8e-171 ydhF S Aldo keto reductase
LCAHJLOB_01027 1.2e-08 S Protein of unknown function (DUF3169)
LCAHJLOB_01028 2.5e-27 XK27_07105 K transcriptional
LCAHJLOB_01029 2.1e-38
LCAHJLOB_01030 2.3e-53 S Bacterial protein of unknown function (DUF961)
LCAHJLOB_01031 1e-63 S Bacterial protein of unknown function (DUF961)
LCAHJLOB_01032 3.7e-265 D Domain of unknown function DUF87
LCAHJLOB_01033 1.2e-266 expZ S ATPases associated with a variety of cellular activities
LCAHJLOB_01034 4.1e-12 K Transcriptional
LCAHJLOB_01035 9.1e-88 L Replication initiation factor
LCAHJLOB_01036 1.2e-10 S Domain of unknown function (DUF3173)
LCAHJLOB_01037 1.4e-209 L Belongs to the 'phage' integrase family
LCAHJLOB_01038 1.6e-232 K Replication initiation factor
LCAHJLOB_01039 1.9e-30 S Psort location CytoplasmicMembrane, score
LCAHJLOB_01040 7.5e-91 S Antirestriction protein (ArdA)
LCAHJLOB_01041 3.8e-90 S TcpE family
LCAHJLOB_01042 0.0 S AAA-like domain
LCAHJLOB_01043 0.0 S the current gene model (or a revised gene model) may contain a frame shift
LCAHJLOB_01044 2.2e-190 yddH M NlpC p60 family protein
LCAHJLOB_01045 3.7e-168 S Conjugative transposon protein TcpC
LCAHJLOB_01046 0.0 tetM J elongation factor G
LCAHJLOB_01047 6e-58 K Helix-turn-helix domain
LCAHJLOB_01048 1.1e-71 phyR K Sigma-70, region 4
LCAHJLOB_01049 9.3e-36 S Helix-turn-helix domain
LCAHJLOB_01050 1.8e-30 xis S Excisionase from transposon Tn916
LCAHJLOB_01051 1.3e-232 L DNA binding domain of tn916 integrase
LCAHJLOB_01052 7.4e-109 XK27_02070 S nitroreductase
LCAHJLOB_01053 4.8e-149 1.13.11.2 S glyoxalase
LCAHJLOB_01054 8.9e-75 ywnA K Transcriptional regulator
LCAHJLOB_01055 6.3e-154 E Alpha/beta hydrolase of unknown function (DUF915)
LCAHJLOB_01056 8.7e-224 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LCAHJLOB_01057 2.7e-109 drgA C nitroreductase
LCAHJLOB_01058 1.6e-104 yoaK S Protein of unknown function (DUF1275)
LCAHJLOB_01059 2e-39 DJ nuclease activity
LCAHJLOB_01060 1.9e-30 XK27_10490
LCAHJLOB_01061 5.4e-158 yvgN C reductase
LCAHJLOB_01062 9.3e-209 S Tetratricopeptide repeat
LCAHJLOB_01063 0.0 lacL 3.2.1.23 G -beta-galactosidase
LCAHJLOB_01064 0.0 lacS G transporter
LCAHJLOB_01065 1.9e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LCAHJLOB_01066 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LCAHJLOB_01067 1.7e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
LCAHJLOB_01068 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LCAHJLOB_01069 4.9e-182 galR K Transcriptional regulator
LCAHJLOB_01070 8.4e-309 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
LCAHJLOB_01071 1.6e-225 vncS 2.7.13.3 T Histidine kinase
LCAHJLOB_01072 1.7e-114 K Response regulator receiver domain protein
LCAHJLOB_01073 8.6e-238 vex3 V Efflux ABC transporter, permease protein
LCAHJLOB_01074 2.8e-106 vex2 V abc transporter atp-binding protein
LCAHJLOB_01075 2.2e-179 vex1 V Efflux ABC transporter, permease protein
LCAHJLOB_01076 1.5e-283 XK27_07020 S Belongs to the UPF0371 family
LCAHJLOB_01078 2.2e-199 gldA 1.1.1.6 C glycerol dehydrogenase
LCAHJLOB_01079 7.7e-180 XK27_10475 S oxidoreductase
LCAHJLOB_01080 1.3e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
LCAHJLOB_01081 3.4e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
LCAHJLOB_01082 1e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
LCAHJLOB_01083 1.8e-226 thrE K Psort location CytoplasmicMembrane, score
LCAHJLOB_01084 0.0 M Putative cell wall binding repeat
LCAHJLOB_01085 3.5e-133 T Ser Thr phosphatase family protein
LCAHJLOB_01086 7.1e-34 S Immunity protein 41
LCAHJLOB_01087 0.0 pepO 3.4.24.71 O Peptidase family M13
LCAHJLOB_01088 7.6e-07 S Enterocin A Immunity
LCAHJLOB_01089 1e-14 S integral membrane protein
LCAHJLOB_01090 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
LCAHJLOB_01091 2.8e-107 yhfC S Putative membrane peptidase family (DUF2324)
LCAHJLOB_01092 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LCAHJLOB_01094 1.7e-258 S dextransucrase activity
LCAHJLOB_01095 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LCAHJLOB_01096 0.0 S dextransucrase activity
LCAHJLOB_01097 0.0 S dextransucrase activity
LCAHJLOB_01098 0.0 S dextransucrase activity
LCAHJLOB_01099 4.7e-88 M Putative cell wall binding repeat
LCAHJLOB_01100 0.0 S dextransucrase activity
LCAHJLOB_01101 1.1e-99 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LCAHJLOB_01102 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LCAHJLOB_01103 0.0 M Putative cell wall binding repeat
LCAHJLOB_01104 1.7e-303 S dextransucrase activity
LCAHJLOB_01105 1.4e-174 M Putative cell wall binding repeat
LCAHJLOB_01106 0.0 S dextransucrase activity
LCAHJLOB_01107 0.0 M Putative cell wall binding repeat
LCAHJLOB_01108 2.6e-263 S dextransucrase activity
LCAHJLOB_01109 0.0 M Putative cell wall binding repeat
LCAHJLOB_01111 1.7e-104 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LCAHJLOB_01112 2.9e-160 mleP S Sodium Bile acid symporter family
LCAHJLOB_01113 4.5e-311 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
LCAHJLOB_01114 1.5e-45 K Helix-turn-helix
LCAHJLOB_01115 2.2e-117 mleR K Transcriptional regulator
LCAHJLOB_01116 1.5e-111 XK27_00785 S CAAX protease self-immunity
LCAHJLOB_01117 1.4e-232 EGP Major facilitator Superfamily
LCAHJLOB_01118 7.9e-62 rmaI K Transcriptional regulator, MarR family
LCAHJLOB_01119 2.7e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
LCAHJLOB_01120 6.3e-134 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
LCAHJLOB_01121 0.0 3.5.1.28 M domain protein
LCAHJLOB_01122 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LCAHJLOB_01123 4.3e-15
LCAHJLOB_01130 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCAHJLOB_01131 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LCAHJLOB_01132 4.4e-228 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LCAHJLOB_01133 2.5e-231 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
LCAHJLOB_01135 8.7e-60 divIC D Septum formation initiator
LCAHJLOB_01136 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LCAHJLOB_01137 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LCAHJLOB_01138 5.2e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LCAHJLOB_01139 3.3e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LCAHJLOB_01140 1.6e-28 yyzM S Protein conserved in bacteria
LCAHJLOB_01141 1.6e-197 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LCAHJLOB_01142 2.2e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LCAHJLOB_01143 3.2e-133 parB K Belongs to the ParB family
LCAHJLOB_01144 1.5e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
LCAHJLOB_01145 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LCAHJLOB_01146 2.2e-117 yoaK S Protein of unknown function (DUF1275)
LCAHJLOB_01150 0.0 XK27_10405 S Bacterial membrane protein YfhO
LCAHJLOB_01151 1.1e-305 ybiT S abc transporter atp-binding protein
LCAHJLOB_01152 9.3e-153 yvjA S membrane
LCAHJLOB_01153 7.2e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LCAHJLOB_01154 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LCAHJLOB_01155 3.7e-199 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LCAHJLOB_01156 1.9e-57 yaaA S S4 domain protein YaaA
LCAHJLOB_01157 2.5e-228 ymfF S Peptidase M16
LCAHJLOB_01158 9.2e-234 ymfH S Peptidase M16
LCAHJLOB_01159 1e-127 S sequence-specific DNA binding
LCAHJLOB_01160 2.6e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LCAHJLOB_01161 3.5e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCAHJLOB_01162 1.2e-149 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCAHJLOB_01163 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCAHJLOB_01164 5.9e-71 lytE M LysM domain protein
LCAHJLOB_01165 3.5e-62 isaA GH23 M Immunodominant staphylococcal antigen A
LCAHJLOB_01166 2.1e-305 S Bacterial membrane protein, YfhO
LCAHJLOB_01167 4.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LCAHJLOB_01168 8.7e-97 yvbG U UPF0056 membrane protein
LCAHJLOB_01169 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LCAHJLOB_01170 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LCAHJLOB_01171 2.2e-73 rplI J binds to the 23S rRNA
LCAHJLOB_01172 1.9e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LCAHJLOB_01173 1.8e-47 veg S Biofilm formation stimulator VEG
LCAHJLOB_01174 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LCAHJLOB_01175 4.2e-10
LCAHJLOB_01176 4.5e-53 ypaA M Membrane
LCAHJLOB_01177 2.1e-94 XK27_06935 K transcriptional regulator
LCAHJLOB_01178 4.7e-159 XK27_06930 V domain protein
LCAHJLOB_01179 3.1e-105 S Putative adhesin
LCAHJLOB_01180 6.8e-59 XK27_06920 S Protein of unknown function (DUF1700)
LCAHJLOB_01181 1.6e-52 K transcriptional regulator, PadR family
LCAHJLOB_01182 2.2e-116 nudL L hydrolase
LCAHJLOB_01185 1.9e-07
LCAHJLOB_01186 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LCAHJLOB_01187 3.4e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LCAHJLOB_01188 4.7e-218 metE 2.1.1.14 E Methionine synthase
LCAHJLOB_01189 1.4e-07 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LCAHJLOB_01190 1.5e-28 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LCAHJLOB_01191 6.7e-57 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LCAHJLOB_01192 9.2e-24 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LCAHJLOB_01193 8e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
LCAHJLOB_01195 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LCAHJLOB_01196 9.3e-167 XK27_01785 S cog cog1284
LCAHJLOB_01197 1.5e-119 yaaA S Belongs to the UPF0246 family
LCAHJLOB_01198 2.6e-114 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCAHJLOB_01199 3.1e-84 XK27_10930 K acetyltransferase
LCAHJLOB_01200 2.8e-13
LCAHJLOB_01201 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LCAHJLOB_01202 3.4e-289 ccs S the current gene model (or a revised gene model) may contain a frame shift
LCAHJLOB_01203 3.2e-44 yrzB S Belongs to the UPF0473 family
LCAHJLOB_01204 1.5e-68 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LCAHJLOB_01205 6.3e-44 yrzL S Belongs to the UPF0297 family
LCAHJLOB_01206 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LCAHJLOB_01207 3.7e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
LCAHJLOB_01209 4.7e-213 int L Belongs to the 'phage' integrase family
LCAHJLOB_01210 1.4e-18 S Domain of unknown function (DUF3173)
LCAHJLOB_01211 1.5e-156 L Replication initiation factor
LCAHJLOB_01212 5e-90 K sequence-specific DNA binding
LCAHJLOB_01213 5.1e-82 S Short repeat of unknown function (DUF308)
LCAHJLOB_01214 4.5e-91 adk 2.7.4.3 F topology modulation protein
LCAHJLOB_01215 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LCAHJLOB_01216 2.2e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LCAHJLOB_01217 2.8e-35 XK27_09805 S MORN repeat protein
LCAHJLOB_01218 0.0 XK27_09800 I Acyltransferase
LCAHJLOB_01219 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LCAHJLOB_01220 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
LCAHJLOB_01221 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LCAHJLOB_01222 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
LCAHJLOB_01223 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LCAHJLOB_01224 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LCAHJLOB_01225 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LCAHJLOB_01226 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LCAHJLOB_01227 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LCAHJLOB_01228 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LCAHJLOB_01229 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
LCAHJLOB_01230 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LCAHJLOB_01231 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LCAHJLOB_01232 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LCAHJLOB_01233 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LCAHJLOB_01234 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LCAHJLOB_01235 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LCAHJLOB_01236 9.6e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LCAHJLOB_01237 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LCAHJLOB_01238 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LCAHJLOB_01239 1.9e-23 rpmD J ribosomal protein l30
LCAHJLOB_01240 3.7e-57 rplO J binds to the 23S rRNA
LCAHJLOB_01241 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LCAHJLOB_01242 7.3e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LCAHJLOB_01243 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LCAHJLOB_01244 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LCAHJLOB_01245 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LCAHJLOB_01246 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LCAHJLOB_01247 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCAHJLOB_01248 4.4e-62 rplQ J ribosomal protein l17
LCAHJLOB_01249 2.9e-243 6.3.2.2 H gamma-glutamylcysteine synthetase
LCAHJLOB_01251 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
LCAHJLOB_01252 9.1e-200 L DNA integration
LCAHJLOB_01253 1.5e-15
LCAHJLOB_01255 2.4e-169 isp2 S pathogenesis
LCAHJLOB_01256 6.7e-31
LCAHJLOB_01257 3.2e-259
LCAHJLOB_01258 0.0 yddE S AAA-like domain
LCAHJLOB_01259 5.1e-69 S TcpE family
LCAHJLOB_01260 3.2e-33
LCAHJLOB_01261 6.6e-163 S Conjugative transposon protein TcpC
LCAHJLOB_01262 7.4e-87
LCAHJLOB_01263 4.3e-33
LCAHJLOB_01264 3.2e-223 K Replication initiation factor
LCAHJLOB_01265 1.3e-280 ydcQ D Ftsk spoiiie family protein
LCAHJLOB_01266 7.7e-74
LCAHJLOB_01267 1.3e-42
LCAHJLOB_01268 1.2e-47 K Helix-turn-helix XRE-family like proteins
LCAHJLOB_01270 1.3e-127 E IrrE N-terminal-like domain
LCAHJLOB_01271 9.5e-108 K Peptidase S24-like protein
LCAHJLOB_01272 6.9e-23
LCAHJLOB_01273 6.7e-37 K Putative DNA-binding domain
LCAHJLOB_01274 2.5e-66 avaIR 3.1.21.4 J PFAM Restriction endonuclease BsobI
LCAHJLOB_01275 1.4e-127 2.1.1.113 L Belongs to the N(4) N(6)-methyltransferase family
LCAHJLOB_01276 4.9e-220 3.6.4.12 K Divergent AAA domain protein
LCAHJLOB_01278 1.9e-95 ywlG S Belongs to the UPF0340 family
LCAHJLOB_01279 2.3e-84 treR K trehalose operon
LCAHJLOB_01280 2e-180 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LCAHJLOB_01281 0.0 pepO 3.4.24.71 O Peptidase family M13
LCAHJLOB_01282 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LCAHJLOB_01285 2.1e-274 thrC 4.2.3.1 E Threonine synthase
LCAHJLOB_01286 6e-225 norN V Mate efflux family protein
LCAHJLOB_01287 1.4e-57 asp S cog cog1302
LCAHJLOB_01288 7.1e-303 yloV S kinase related to dihydroxyacetone kinase
LCAHJLOB_01289 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LCAHJLOB_01290 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
LCAHJLOB_01291 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
LCAHJLOB_01292 3.7e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LCAHJLOB_01293 5.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LCAHJLOB_01294 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LCAHJLOB_01295 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCAHJLOB_01296 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCAHJLOB_01297 1e-68 S cog cog4699
LCAHJLOB_01298 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCAHJLOB_01299 6.3e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCAHJLOB_01300 6.5e-43 comGC U Required for transformation and DNA binding
LCAHJLOB_01301 7.1e-69 cglD NU Competence protein
LCAHJLOB_01302 1.1e-15 NU Type II secretory pathway pseudopilin
LCAHJLOB_01303 3.8e-70 comGF U Competence protein ComGF
LCAHJLOB_01304 2.4e-13 comGF U Putative Competence protein ComGF
LCAHJLOB_01305 5.5e-175 ytxK 2.1.1.72 L DNA methylase
LCAHJLOB_01306 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LCAHJLOB_01307 1.5e-26 lanR K sequence-specific DNA binding
LCAHJLOB_01308 3.2e-105 V CAAX protease self-immunity
LCAHJLOB_01310 4e-100 S CAAX amino terminal protease family protein
LCAHJLOB_01311 2.6e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCAHJLOB_01312 1.3e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LCAHJLOB_01313 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
LCAHJLOB_01314 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LCAHJLOB_01315 9e-10 S NTF2 fold immunity protein
LCAHJLOB_01316 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LCAHJLOB_01317 4.7e-120 S CAAX protease self-immunity
LCAHJLOB_01318 1.5e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LCAHJLOB_01319 5.6e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LCAHJLOB_01323 1.7e-156 rrmA 2.1.1.187 Q methyltransferase
LCAHJLOB_01324 6.8e-128 S HAD hydrolase, family IA, variant
LCAHJLOB_01325 1.5e-57 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LCAHJLOB_01326 7.4e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LCAHJLOB_01327 7.7e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LCAHJLOB_01328 2.7e-115 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
LCAHJLOB_01329 1.9e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LCAHJLOB_01330 2.6e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LCAHJLOB_01331 1.9e-95 XK27_08585 S Psort location CytoplasmicMembrane, score
LCAHJLOB_01332 1.6e-140 fnt P Formate nitrite transporter
LCAHJLOB_01333 7.9e-230 XK27_09615 C reductase
LCAHJLOB_01334 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
LCAHJLOB_01335 3.2e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
LCAHJLOB_01336 2.6e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
LCAHJLOB_01337 7.5e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LCAHJLOB_01338 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
LCAHJLOB_01339 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
LCAHJLOB_01340 1.6e-50 S Protein of unknown function (DUF3397)
LCAHJLOB_01341 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LCAHJLOB_01342 5.3e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LCAHJLOB_01343 0.0 amiA E ABC transporter, substrate-binding protein, family 5
LCAHJLOB_01344 1.6e-271 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LCAHJLOB_01345 9.1e-229 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
LCAHJLOB_01346 9.5e-153 hpk9 2.7.13.3 T protein histidine kinase activity
LCAHJLOB_01347 5.6e-207 hpk9 2.7.13.3 T protein histidine kinase activity
LCAHJLOB_01348 2.8e-225 fasC T protein histidine kinase activity
LCAHJLOB_01349 4.7e-129 fasA KT Response regulator of the LytR AlgR family
LCAHJLOB_01350 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LCAHJLOB_01351 7.8e-263 argH 4.3.2.1 E Argininosuccinate lyase
LCAHJLOB_01352 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LCAHJLOB_01353 1.7e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LCAHJLOB_01354 3.5e-167 jag S RNA-binding protein
LCAHJLOB_01355 9.9e-98 K Transcriptional regulator
LCAHJLOB_01356 2.7e-97 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
LCAHJLOB_01357 3.4e-14 rpmH J Ribosomal protein L34
LCAHJLOB_01358 2.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LCAHJLOB_01359 4.6e-35 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LCAHJLOB_01360 4.7e-17
LCAHJLOB_01361 0.0 3.2.1.97, 4.2.2.1 GH101,PL8 N Leucine rich repeats (6 copies)
LCAHJLOB_01363 6.4e-20 S Ribosomal protein S1-like RNA-binding domain
LCAHJLOB_01365 2.1e-127 U TraM recognition site of TraD and TraG
LCAHJLOB_01372 1.7e-146 K sequence-specific DNA binding
LCAHJLOB_01373 3.8e-35 M Psort location Cytoplasmic, score 8.96
LCAHJLOB_01374 2.3e-22 JM COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LCAHJLOB_01376 1.8e-12
LCAHJLOB_01378 9.8e-13 S Oxidoreductase family, C-terminal alpha/beta domain
LCAHJLOB_01379 6e-20 IQ KR domain
LCAHJLOB_01381 4.9e-45
LCAHJLOB_01385 2.4e-139 natA V ATPases associated with a variety of cellular activities
LCAHJLOB_01386 1e-126 V ABC-2 type transporter
LCAHJLOB_01387 3.1e-131 V ABC-2 type transporter
LCAHJLOB_01389 6.2e-90
LCAHJLOB_01390 1.2e-15 L Transposase, IS605 OrfB family
LCAHJLOB_01393 2.1e-33 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LCAHJLOB_01394 6.4e-66 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
LCAHJLOB_01395 4.9e-09 S ERF superfamily
LCAHJLOB_01400 9.6e-30 radC E Belongs to the UPF0758 family
LCAHJLOB_01409 3.7e-105 abiGI K Transcriptional regulator, AbiEi antitoxin
LCAHJLOB_01410 2.1e-15 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
LCAHJLOB_01411 2.6e-180
LCAHJLOB_01412 8.6e-79 FNV0100 F Belongs to the Nudix hydrolase family
LCAHJLOB_01413 2.2e-78 XK27_01300 P Protein conserved in bacteria
LCAHJLOB_01415 1e-246 S Protein of unknown function DUF262
LCAHJLOB_01416 2e-25
LCAHJLOB_01418 5e-196 L the current gene model (or a revised gene model) may contain a frame shift
LCAHJLOB_01419 9.7e-66 ytxH S General stress protein
LCAHJLOB_01420 3.1e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LCAHJLOB_01421 2.9e-145 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LCAHJLOB_01422 1.9e-167 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LCAHJLOB_01423 2.2e-41 pspC KT PspC domain
LCAHJLOB_01424 1.1e-82 ydcK S Belongs to the SprT family
LCAHJLOB_01425 0.0 yhgF K Transcriptional accessory protein
LCAHJLOB_01427 6e-155 XK27_03015 S permease
LCAHJLOB_01428 1.2e-146 ycgQ S TIGR03943 family
LCAHJLOB_01429 2.1e-278 sulP P Sulfate permease and related transporters (MFS superfamily)
LCAHJLOB_01430 6.4e-100
LCAHJLOB_01431 4.6e-48 estA E GDSL-like Lipase/Acylhydrolase
LCAHJLOB_01432 1.4e-91 S CAAX protease self-immunity
LCAHJLOB_01434 1.6e-50
LCAHJLOB_01436 4.8e-63 yqeB S Pyrimidine dimer DNA glycosylase
LCAHJLOB_01437 1.9e-60 S Protein of unknown function (DUF1722)
LCAHJLOB_01438 2.9e-19 M Bacterial lipoprotein
LCAHJLOB_01439 5.8e-10
LCAHJLOB_01440 5.2e-128 V CAAX protease self-immunity
LCAHJLOB_01441 1.2e-44
LCAHJLOB_01442 5.8e-66 K TetR family transcriptional regulator
LCAHJLOB_01443 3.5e-79 Q Methyltransferase domain
LCAHJLOB_01444 9.4e-143 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LCAHJLOB_01445 1.3e-174 acoB C dehydrogenase E1 component
LCAHJLOB_01446 2.8e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
LCAHJLOB_01447 4.3e-173 pdhD 1.8.1.4 C Dehydrogenase
LCAHJLOB_01448 3.3e-08 K CsbD-like
LCAHJLOB_01449 3.3e-08 K CsbD-like
LCAHJLOB_01450 7.7e-68 S Asp23 family, cell envelope-related function
LCAHJLOB_01451 1.5e-22 S Small integral membrane protein
LCAHJLOB_01452 4.7e-97
LCAHJLOB_01453 2.3e-29 S Membrane
LCAHJLOB_01455 6.8e-171 S Domain of unknown function (DUF389)
LCAHJLOB_01456 3.7e-157 yegS 2.7.1.107 I Diacylglycerol kinase
LCAHJLOB_01457 1.2e-123 ybbA S Putative esterase
LCAHJLOB_01458 2.5e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LCAHJLOB_01459 4.9e-134 fecE 3.6.3.34 HP ABC transporter
LCAHJLOB_01460 1.4e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCAHJLOB_01461 2.1e-116 V CAAX protease self-immunity
LCAHJLOB_01462 3.5e-149 S Domain of unknown function (DUF4300)
LCAHJLOB_01463 6.3e-91 tetR K transcriptional regulator
LCAHJLOB_01464 1.8e-280 norB P Major facilitator superfamily
LCAHJLOB_01465 7.1e-21 S Domain of unknown function (DUF4767)
LCAHJLOB_01467 2.5e-107 cutC P Participates in the control of copper homeostasis
LCAHJLOB_01468 2.9e-94 XK27_08140 K Bacterial regulatory proteins, tetR family
LCAHJLOB_01469 7.8e-149 yitS S EDD domain protein, DegV family
LCAHJLOB_01470 7e-204 yeaN P transporter
LCAHJLOB_01471 5.8e-132 S Domain of unknown function (DUF4336)
LCAHJLOB_01472 1.8e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LCAHJLOB_01473 1.7e-12
LCAHJLOB_01474 7.7e-297 V ABC transporter transmembrane region
LCAHJLOB_01475 7.9e-129 bcrA V abc transporter atp-binding protein
LCAHJLOB_01476 1e-115 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
LCAHJLOB_01477 8.8e-113 K Bacterial regulatory proteins, tetR family
LCAHJLOB_01478 4e-96
LCAHJLOB_01479 2e-97 J Acetyltransferase (GNAT) domain
LCAHJLOB_01480 1.5e-130 S CAAX protease self-immunity
LCAHJLOB_01481 8.3e-105 3.4.13.21, 3.4.15.6 E Belongs to the peptidase S51 family
LCAHJLOB_01482 1.1e-77 aacA7 2.3.1.82 K Acetyltransferase (GNAT) family
LCAHJLOB_01483 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCAHJLOB_01484 5.9e-55
LCAHJLOB_01485 8.7e-60
LCAHJLOB_01486 1.1e-49
LCAHJLOB_01487 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
LCAHJLOB_01488 2e-217 EGP Transmembrane secretion effector
LCAHJLOB_01489 4.3e-22
LCAHJLOB_01491 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LCAHJLOB_01492 1.6e-61 smtB K Transcriptional regulator
LCAHJLOB_01493 1.1e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
LCAHJLOB_01494 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
LCAHJLOB_01495 5e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCAHJLOB_01496 2e-97 mip S hydroperoxide reductase activity
LCAHJLOB_01497 8.5e-201 I acyl-CoA dehydrogenase
LCAHJLOB_01498 1e-149 ydiA P C4-dicarboxylate transporter malic acid transport
LCAHJLOB_01499 4.4e-245 msrR K Transcriptional regulator
LCAHJLOB_01500 8.8e-153 pheA 4.2.1.51 E Prephenate dehydratase
LCAHJLOB_01501 4.7e-77 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LCAHJLOB_01502 2.1e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LCAHJLOB_01503 1.4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LCAHJLOB_01504 4.2e-53 yheA S Belongs to the UPF0342 family
LCAHJLOB_01505 2e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LCAHJLOB_01506 4.9e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LCAHJLOB_01507 3.8e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LCAHJLOB_01508 3.3e-155 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LCAHJLOB_01509 4.4e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LCAHJLOB_01510 1.1e-214 ywbD 2.1.1.191 J Methyltransferase
LCAHJLOB_01511 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LCAHJLOB_01512 4.6e-25 WQ51_00785
LCAHJLOB_01513 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LCAHJLOB_01514 1.1e-75 yueI S Protein of unknown function (DUF1694)
LCAHJLOB_01515 1.5e-195 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LCAHJLOB_01516 4.3e-192 yyaQ S YjbR
LCAHJLOB_01517 1.2e-180 ccpA K Catabolite control protein A
LCAHJLOB_01518 1.1e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
LCAHJLOB_01519 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
LCAHJLOB_01520 4.1e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LCAHJLOB_01521 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LCAHJLOB_01522 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LCAHJLOB_01523 2e-33 secG U Preprotein translocase subunit SecG
LCAHJLOB_01524 2.9e-221 mdtG EGP Major facilitator Superfamily
LCAHJLOB_01525 2.6e-93 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LCAHJLOB_01526 2.2e-143 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LCAHJLOB_01527 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LCAHJLOB_01528 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LCAHJLOB_01529 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LCAHJLOB_01530 6.2e-146 licT K antiterminator
LCAHJLOB_01531 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LCAHJLOB_01532 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
LCAHJLOB_01533 4.4e-144 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LCAHJLOB_01534 6.3e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LCAHJLOB_01535 6.1e-148 I Alpha/beta hydrolase family
LCAHJLOB_01536 6.6e-08
LCAHJLOB_01537 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
LCAHJLOB_01538 2.9e-76 feoA P FeoA domain protein
LCAHJLOB_01539 3.2e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
LCAHJLOB_01540 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
LCAHJLOB_01541 1e-34 ykuJ S protein conserved in bacteria
LCAHJLOB_01542 3.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LCAHJLOB_01543 0.0 clpE O Belongs to the ClpA ClpB family
LCAHJLOB_01544 2.2e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LCAHJLOB_01545 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
LCAHJLOB_01546 1.5e-172 S oxidoreductase
LCAHJLOB_01547 2.5e-228 murN 2.3.2.16 V FemAB family
LCAHJLOB_01548 1.2e-115 M Pfam SNARE associated Golgi protein
LCAHJLOB_01549 2.1e-106 S Domain of Unknown Function with PDB structure (DUF3862)
LCAHJLOB_01552 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
LCAHJLOB_01555 4.8e-16 S Protein of unknown function (DUF2969)
LCAHJLOB_01556 4.5e-199 ilvE 2.6.1.42 E Aminotransferase
LCAHJLOB_01557 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LCAHJLOB_01558 8.1e-11
LCAHJLOB_01559 9.7e-07
LCAHJLOB_01560 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LCAHJLOB_01561 5.6e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LCAHJLOB_01562 1.4e-12 L Helix-hairpin-helix DNA-binding motif class 1
LCAHJLOB_01563 2.2e-30 S Domain of unknown function (DUF1912)
LCAHJLOB_01564 1.4e-167 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
LCAHJLOB_01565 2.1e-180 mmuP E amino acid
LCAHJLOB_01566 1.4e-50 mmuP E amino acid
LCAHJLOB_01567 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
LCAHJLOB_01568 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LCAHJLOB_01569 9.7e-22
LCAHJLOB_01570 4.9e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LCAHJLOB_01571 1.6e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LCAHJLOB_01572 1.1e-209 mvaS 2.3.3.10 I synthase
LCAHJLOB_01573 3.5e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LCAHJLOB_01574 3e-78 K hmm pf08876
LCAHJLOB_01575 1.2e-118 yqfA K protein, Hemolysin III
LCAHJLOB_01576 1.2e-28 pspC KT PspC domain protein
LCAHJLOB_01577 3.5e-194 S Protein of unknown function (DUF3114)
LCAHJLOB_01578 2.8e-147 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LCAHJLOB_01579 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LCAHJLOB_01580 8.8e-10
LCAHJLOB_01581 1.3e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
LCAHJLOB_01582 1.7e-190 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
LCAHJLOB_01583 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LCAHJLOB_01584 5e-98 comFC K competence protein
LCAHJLOB_01585 8.3e-238 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LCAHJLOB_01586 2.2e-108 yvyE 3.4.13.9 S YigZ family
LCAHJLOB_01587 7e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LCAHJLOB_01588 2.5e-110 acuB S CBS domain
LCAHJLOB_01589 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
LCAHJLOB_01590 4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
LCAHJLOB_01591 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
LCAHJLOB_01592 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
LCAHJLOB_01593 1.4e-209 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
LCAHJLOB_01594 1.6e-45 ylbG S UPF0298 protein
LCAHJLOB_01595 5.8e-74 ylbF S Belongs to the UPF0342 family
LCAHJLOB_01596 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LCAHJLOB_01597 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LCAHJLOB_01598 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
LCAHJLOB_01599 1.3e-296 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
LCAHJLOB_01600 5.3e-220 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LCAHJLOB_01601 3e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
LCAHJLOB_01602 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
LCAHJLOB_01603 2.6e-278 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
LCAHJLOB_01604 9.3e-267 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LCAHJLOB_01605 1.2e-97 yvdD 3.2.2.10 S Belongs to the LOG family
LCAHJLOB_01606 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LCAHJLOB_01607 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LCAHJLOB_01608 1.4e-41 ylxQ J ribosomal protein
LCAHJLOB_01609 2.3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
LCAHJLOB_01610 4e-199 nusA K Participates in both transcription termination and antitermination
LCAHJLOB_01611 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
LCAHJLOB_01612 2e-188 brpA K Transcriptional
LCAHJLOB_01613 8.7e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
LCAHJLOB_01614 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
LCAHJLOB_01615 4.7e-247 pbuO S permease
LCAHJLOB_01616 1.5e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LCAHJLOB_01617 2.3e-136 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
LCAHJLOB_01618 8.1e-169 manL 2.7.1.191 G pts system
LCAHJLOB_01619 4.7e-135 manY G pts system
LCAHJLOB_01620 3.6e-163 manN G PTS system mannose fructose sorbose family IID component
LCAHJLOB_01621 5.9e-67 manO S Protein conserved in bacteria
LCAHJLOB_01622 3.1e-173 manL 2.7.1.191 G pts system
LCAHJLOB_01623 1.3e-116 manM G pts system
LCAHJLOB_01624 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
LCAHJLOB_01625 2.5e-62 manO S protein conserved in bacteria
LCAHJLOB_01626 3.1e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LCAHJLOB_01627 6.8e-105
LCAHJLOB_01628 9.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LCAHJLOB_01629 2.4e-164 dnaI L Primosomal protein DnaI
LCAHJLOB_01630 2.5e-209 dnaB L Replication initiation and membrane attachment
LCAHJLOB_01631 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LCAHJLOB_01632 2.5e-278 T PhoQ Sensor
LCAHJLOB_01633 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LCAHJLOB_01634 5.2e-90 yceD K metal-binding, possibly nucleic acid-binding protein
LCAHJLOB_01635 2.5e-127 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
LCAHJLOB_01636 3.4e-234 P COG0168 Trk-type K transport systems, membrane components
LCAHJLOB_01637 8.2e-117 ktrA P COG0569 K transport systems, NAD-binding component
LCAHJLOB_01638 3.2e-147 cbiQ P cobalt transport
LCAHJLOB_01639 9.6e-308 ykoD P abc transporter atp-binding protein
LCAHJLOB_01640 6.7e-93 S UPF0397 protein
LCAHJLOB_01641 1.2e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
LCAHJLOB_01642 1.9e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LCAHJLOB_01643 1.2e-99 metI P ABC transporter (Permease
LCAHJLOB_01644 1.1e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LCAHJLOB_01645 7.2e-261 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
LCAHJLOB_01646 1.7e-162 metQ M Belongs to the NlpA lipoprotein family
LCAHJLOB_01647 1.8e-137 ET ABC transporter substrate-binding protein
LCAHJLOB_01648 2.9e-128 cbiO P ABC transporter
LCAHJLOB_01649 6.4e-137 P cobalt transport protein
LCAHJLOB_01650 2.1e-177 cbiM P PDGLE domain
LCAHJLOB_01651 3.7e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LCAHJLOB_01652 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LCAHJLOB_01653 2.9e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LCAHJLOB_01654 6.6e-78 ureE O enzyme active site formation
LCAHJLOB_01655 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LCAHJLOB_01656 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LCAHJLOB_01657 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LCAHJLOB_01658 6.8e-95 ureI S AmiS/UreI family transporter
LCAHJLOB_01659 7.8e-112 S Domain of unknown function (DUF4173)
LCAHJLOB_01660 1.7e-103 S Domain of unknown function (DUF4173)
LCAHJLOB_01661 3.2e-53 yhaI L Membrane
LCAHJLOB_01662 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LCAHJLOB_01663 2.7e-155 K sequence-specific DNA binding
LCAHJLOB_01664 4.9e-90 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
LCAHJLOB_01665 3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LCAHJLOB_01666 5.1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LCAHJLOB_01667 9.3e-245 trkA P Potassium transporter peripheral membrane component
LCAHJLOB_01668 6e-258 trkH P Cation transport protein
LCAHJLOB_01669 4.4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LCAHJLOB_01670 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LCAHJLOB_01671 9.1e-96 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LCAHJLOB_01672 3.4e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LCAHJLOB_01673 2.7e-127 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
LCAHJLOB_01674 3.5e-85 ykuL S CBS domain
LCAHJLOB_01675 1.3e-96 XK27_09740 S Phosphoesterase
LCAHJLOB_01676 2.8e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LCAHJLOB_01677 7.6e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LCAHJLOB_01678 1.6e-36 yneF S UPF0154 protein
LCAHJLOB_01679 4.5e-89 K transcriptional regulator
LCAHJLOB_01680 3.1e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LCAHJLOB_01681 3.2e-12 ycdA S Domain of unknown function (DUF4352)
LCAHJLOB_01682 5e-101 ybhL S Belongs to the BI1 family
LCAHJLOB_01683 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
LCAHJLOB_01684 1.5e-127 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCAHJLOB_01685 2.5e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LCAHJLOB_01686 1.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LCAHJLOB_01687 1.7e-76 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LCAHJLOB_01688 2.7e-293 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LCAHJLOB_01689 1.2e-85 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
LCAHJLOB_01690 3.4e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LCAHJLOB_01691 4.8e-22
LCAHJLOB_01692 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
LCAHJLOB_01693 2.6e-275 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
LCAHJLOB_01694 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LCAHJLOB_01695 2.1e-36 gpsB D regulation of cell shape
LCAHJLOB_01696 5.8e-94 ypsA S Belongs to the UPF0398 family
LCAHJLOB_01697 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LCAHJLOB_01698 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LCAHJLOB_01699 2.7e-252 pepC 3.4.22.40 E aminopeptidase
LCAHJLOB_01700 1.1e-72 yhaI S Protein of unknown function (DUF805)
LCAHJLOB_01701 3.8e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LCAHJLOB_01702 8.7e-273 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCAHJLOB_01703 2.3e-216 macB_2 V FtsX-like permease family
LCAHJLOB_01704 4.7e-120 yhcA V abc transporter atp-binding protein
LCAHJLOB_01705 3.7e-123 mta K Transcriptional
LCAHJLOB_01706 2.3e-32 S Protein of unknown function (DUF3021)
LCAHJLOB_01707 9e-75 K COG3279 Response regulator of the LytR AlgR family
LCAHJLOB_01708 1.8e-132 cylB V ABC-2 type transporter
LCAHJLOB_01709 2.5e-150 cylA V abc transporter atp-binding protein
LCAHJLOB_01710 4e-53 K regulation of RNA biosynthetic process
LCAHJLOB_01711 3.9e-45 3.2.2.21 S YCII-related domain
LCAHJLOB_01712 6.1e-38 yjdF S Protein of unknown function (DUF2992)
LCAHJLOB_01713 8.8e-234 S COG1073 Hydrolases of the alpha beta superfamily
LCAHJLOB_01714 1e-73 K transcriptional
LCAHJLOB_01715 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LCAHJLOB_01716 5e-134 glcR K transcriptional regulator (DeoR family)
LCAHJLOB_01717 2.3e-145 cof S Sucrose-6F-phosphate phosphohydrolase
LCAHJLOB_01718 2e-72 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
LCAHJLOB_01719 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
LCAHJLOB_01720 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
LCAHJLOB_01721 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LCAHJLOB_01722 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LCAHJLOB_01723 8e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LCAHJLOB_01724 5.8e-55 S TM2 domain
LCAHJLOB_01725 5.5e-44
LCAHJLOB_01727 3.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LCAHJLOB_01728 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LCAHJLOB_01729 1.4e-142 cmpC S abc transporter atp-binding protein
LCAHJLOB_01730 0.0 WQ51_06230 S ABC transporter
LCAHJLOB_01731 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LCAHJLOB_01732 1.4e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LCAHJLOB_01733 4.6e-143 cdsA 2.7.7.41 S Belongs to the CDS family
LCAHJLOB_01734 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LCAHJLOB_01735 2e-47 yajC U protein transport
LCAHJLOB_01736 6.1e-126 yeeN K transcriptional regulatory protein
LCAHJLOB_01737 1.1e-276 V ABC transporter
LCAHJLOB_01738 1.4e-153 Z012_04635 K sequence-specific DNA binding
LCAHJLOB_01739 8.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
LCAHJLOB_01740 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LCAHJLOB_01741 1.1e-108 L Transposase IS116 IS110 IS902
LCAHJLOB_01742 9.2e-59 L MULE transposase domain
LCAHJLOB_01743 8.1e-16 tnp* L An automated process has identified a potential problem with this gene model
LCAHJLOB_01744 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
LCAHJLOB_01745 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
LCAHJLOB_01746 1.1e-95 srlA G PTS system glucitol sorbitol-specific
LCAHJLOB_01747 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
LCAHJLOB_01748 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
LCAHJLOB_01749 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LCAHJLOB_01750 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
LCAHJLOB_01751 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
LCAHJLOB_01752 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LCAHJLOB_01753 5.5e-159 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
LCAHJLOB_01754 1.9e-128 adcB P ABC transporter (Permease
LCAHJLOB_01755 7.1e-135 adcC P ABC transporter, ATP-binding protein
LCAHJLOB_01756 1e-70 adcR K transcriptional
LCAHJLOB_01757 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCAHJLOB_01758 1.8e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LCAHJLOB_01759 4.7e-26
LCAHJLOB_01760 2.9e-273 sufB O assembly protein SufB
LCAHJLOB_01761 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
LCAHJLOB_01762 1e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LCAHJLOB_01763 6.9e-234 sufD O assembly protein SufD
LCAHJLOB_01764 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LCAHJLOB_01765 1.5e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
LCAHJLOB_01766 1.6e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LCAHJLOB_01767 6.3e-18 S Protein of unknown function (DUF3021)
LCAHJLOB_01768 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LCAHJLOB_01769 5.5e-273 glnP P ABC transporter
LCAHJLOB_01770 2.2e-123 glnQ E abc transporter atp-binding protein
LCAHJLOB_01771 5.8e-179 D nuclear chromosome segregation
LCAHJLOB_01772 2.8e-84 V VanZ like family
LCAHJLOB_01773 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LCAHJLOB_01774 3e-191 yhjX P Major Facilitator
LCAHJLOB_01775 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LCAHJLOB_01776 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LCAHJLOB_01777 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LCAHJLOB_01778 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LCAHJLOB_01779 2e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LCAHJLOB_01780 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCAHJLOB_01781 5.9e-82 nrdI F Belongs to the NrdI family
LCAHJLOB_01782 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LCAHJLOB_01783 9.1e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LCAHJLOB_01784 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
LCAHJLOB_01785 3.8e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
LCAHJLOB_01786 6.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
LCAHJLOB_01787 2.9e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LCAHJLOB_01788 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LCAHJLOB_01789 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LCAHJLOB_01790 1.8e-134 ykuT M mechanosensitive ion channel
LCAHJLOB_01791 8.6e-87 sigH K DNA-templated transcription, initiation
LCAHJLOB_01793 1e-224 L the current gene model (or a revised gene model) may contain a frame shift
LCAHJLOB_01794 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
LCAHJLOB_01795 6e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LCAHJLOB_01796 3.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LCAHJLOB_01797 0.0 dnaE 2.7.7.7 L DNA polymerase
LCAHJLOB_01798 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LCAHJLOB_01799 5.2e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LCAHJLOB_01800 2.5e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LCAHJLOB_01801 7.1e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LCAHJLOB_01802 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LCAHJLOB_01803 2.3e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
LCAHJLOB_01805 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LCAHJLOB_01806 3.4e-95 ypmS S Protein conserved in bacteria
LCAHJLOB_01807 2.2e-154 ypmR E COG2755 Lysophospholipase L1 and related esterases
LCAHJLOB_01808 1.7e-148 DegV S DegV family
LCAHJLOB_01809 3e-301 recN L May be involved in recombinational repair of damaged DNA
LCAHJLOB_01810 2.8e-73 argR K Regulates arginine biosynthesis genes
LCAHJLOB_01811 8.5e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LCAHJLOB_01812 2.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LCAHJLOB_01813 1e-28 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LCAHJLOB_01814 3.9e-235 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LCAHJLOB_01816 3.5e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCAHJLOB_01817 1.1e-124 dnaD
LCAHJLOB_01818 1e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LCAHJLOB_01819 4.9e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCAHJLOB_01820 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
LCAHJLOB_01821 1.5e-65 GnaT 2.5.1.16 K acetyltransferase
LCAHJLOB_01822 1.2e-18 Q Methyltransferase domain
LCAHJLOB_01823 3.7e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LCAHJLOB_01824 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LCAHJLOB_01825 1.5e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
LCAHJLOB_01826 1.1e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCAHJLOB_01827 3.2e-227 rodA D Belongs to the SEDS family
LCAHJLOB_01828 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LCAHJLOB_01829 8.5e-163 L High confidence in function and specificity
LCAHJLOB_01830 2e-42 mccF V LD-carboxypeptidase
LCAHJLOB_01831 1.5e-14 L COG3547 Transposase and inactivated derivatives
LCAHJLOB_01832 4.1e-57 L transposase IS116 IS110 IS902 family
LCAHJLOB_01833 1.7e-100 L COG3547 Transposase and inactivated derivatives
LCAHJLOB_01834 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LCAHJLOB_01835 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
LCAHJLOB_01836 5.2e-179 XK27_08075 M glycosyl transferase family 2
LCAHJLOB_01837 1.8e-96 S Carbohydrate-binding domain-containing protein Cthe_2159
LCAHJLOB_01838 4.4e-146 P molecular chaperone
LCAHJLOB_01839 7.6e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
LCAHJLOB_01841 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
LCAHJLOB_01842 3e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LCAHJLOB_01843 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LCAHJLOB_01844 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LCAHJLOB_01845 2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LCAHJLOB_01846 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LCAHJLOB_01847 1.3e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LCAHJLOB_01848 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LCAHJLOB_01849 6.3e-182 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LCAHJLOB_01850 2.5e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCAHJLOB_01851 1.1e-60 XK27_08085
LCAHJLOB_01852 1.4e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
LCAHJLOB_01853 2.2e-134 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
LCAHJLOB_01854 2.3e-116 ylfI S tigr01906
LCAHJLOB_01855 1e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LCAHJLOB_01856 7.7e-140 fat 3.1.2.21 I Acyl-ACP thioesterase
LCAHJLOB_01857 1.4e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
LCAHJLOB_01858 2.2e-30 KT response to antibiotic
LCAHJLOB_01860 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LCAHJLOB_01861 1.6e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LCAHJLOB_01862 7e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LCAHJLOB_01863 5.8e-255 S phospholipase Carboxylesterase
LCAHJLOB_01864 1.1e-195 yurR 1.4.5.1 E oxidoreductase
LCAHJLOB_01865 5.3e-142 zupT P Mediates zinc uptake. May also transport other divalent cations
LCAHJLOB_01866 4.6e-143 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LCAHJLOB_01867 1.6e-120 trmK 2.1.1.217 S SAM-dependent methyltransferase
LCAHJLOB_01868 1.3e-64 gtrA S GtrA-like protein
LCAHJLOB_01869 1.3e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCAHJLOB_01870 3.2e-162 ybbR S Protein conserved in bacteria
LCAHJLOB_01871 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LCAHJLOB_01872 1.2e-252 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
LCAHJLOB_01873 8.1e-148 cobQ S glutamine amidotransferase
LCAHJLOB_01874 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LCAHJLOB_01875 9.7e-132 pip 1.11.1.10 S Alpha beta hydrolase
LCAHJLOB_01876 1.6e-39 MA20_06245 S yiaA/B two helix domain
LCAHJLOB_01877 0.0 uup S abc transporter atp-binding protein
LCAHJLOB_01878 8.9e-113 udk 2.7.1.48 F Cytidine monophosphokinase
LCAHJLOB_01879 2.2e-175 yfmL 3.6.4.13 L DEAD DEAH box helicase
LCAHJLOB_01880 7.8e-224 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
LCAHJLOB_01881 2.7e-153 XK27_05675 S Esterase
LCAHJLOB_01882 3.9e-161 XK27_05670 S Putative esterase
LCAHJLOB_01883 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
LCAHJLOB_01884 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LCAHJLOB_01885 3e-38 ptsH G phosphocarrier protein Hpr
LCAHJLOB_01886 2.9e-218 icd 1.1.1.42 C Isocitrate dehydrogenase
LCAHJLOB_01887 6.9e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
LCAHJLOB_01888 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LCAHJLOB_01889 6.5e-34 nrdH O Glutaredoxin
LCAHJLOB_01890 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCAHJLOB_01891 3.2e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCAHJLOB_01892 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LCAHJLOB_01893 5.5e-137 divIVA D Cell division initiation protein
LCAHJLOB_01894 3.5e-138 ylmH S conserved protein, contains S4-like domain
LCAHJLOB_01895 1.7e-30 yggT D integral membrane protein
LCAHJLOB_01896 5.6e-93 sepF D cell septum assembly
LCAHJLOB_01897 6.2e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LCAHJLOB_01898 2.8e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LCAHJLOB_01899 1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LCAHJLOB_01900 1.2e-136 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LCAHJLOB_01901 1.2e-197 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LCAHJLOB_01902 4.1e-248 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LCAHJLOB_01904 0.0 typA T GTP-binding protein TypA
LCAHJLOB_01905 2.5e-175 glk 2.7.1.2 G Glucokinase
LCAHJLOB_01906 4.2e-27 yqgQ S protein conserved in bacteria
LCAHJLOB_01907 1.7e-78 perR P Belongs to the Fur family
LCAHJLOB_01908 3.1e-79 dps P Belongs to the Dps family
LCAHJLOB_01909 1.6e-101 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
LCAHJLOB_01910 1.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
LCAHJLOB_01911 7.9e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
LCAHJLOB_01912 5.9e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
LCAHJLOB_01913 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LCAHJLOB_01914 6.2e-64 S Domain of unknown function (DUF4430)
LCAHJLOB_01915 2.1e-74 S Psort location CytoplasmicMembrane, score
LCAHJLOB_01916 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
LCAHJLOB_01917 8.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
LCAHJLOB_01918 9.5e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
LCAHJLOB_01919 9.4e-118 sirR K iron dependent repressor
LCAHJLOB_01920 4e-135 htpX O Belongs to the peptidase M48B family
LCAHJLOB_01921 7.7e-92 lemA S LemA family
LCAHJLOB_01922 1.2e-169 spd F DNA RNA non-specific endonuclease
LCAHJLOB_01923 0.0 M Right handed beta helix region
LCAHJLOB_01924 1.2e-134 S double-stranded DNA endodeoxyribonuclease activity
LCAHJLOB_01925 1.2e-188 L Uncharacterized conserved protein (DUF2075)
LCAHJLOB_01926 1e-43 S Nucleotide pyrophosphohydrolase
LCAHJLOB_01927 5.6e-133 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LCAHJLOB_01928 2.9e-194 MA20_36090 S Protein of unknown function (DUF2974)
LCAHJLOB_01929 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LCAHJLOB_01930 5.6e-155 5.2.1.8 G hydrolase
LCAHJLOB_01931 3e-26 P Hemerythrin HHE cation binding domain protein
LCAHJLOB_01932 9.3e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
LCAHJLOB_01933 3.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LCAHJLOB_01934 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
LCAHJLOB_01936 1.2e-174 S hydrolase
LCAHJLOB_01937 8.4e-23
LCAHJLOB_01938 2e-138 M LysM domain
LCAHJLOB_01939 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LCAHJLOB_01940 4.3e-15
LCAHJLOB_01941 0.0 L helicase
LCAHJLOB_01942 9.5e-65 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
LCAHJLOB_01943 3.3e-12
LCAHJLOB_01944 2.4e-232 mntH P H( )-stimulated, divalent metal cation uptake system
LCAHJLOB_01945 1.1e-33 XK27_12190 S protein conserved in bacteria
LCAHJLOB_01947 1e-85 bioY S biotin synthase
LCAHJLOB_01948 7.5e-252 yegQ O Peptidase U32
LCAHJLOB_01949 2.6e-177 yegQ O Peptidase U32
LCAHJLOB_01951 1e-224 L the current gene model (or a revised gene model) may contain a frame shift
LCAHJLOB_01953 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LCAHJLOB_01954 1.1e-195 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LCAHJLOB_01955 5.8e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LCAHJLOB_01956 1.6e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LCAHJLOB_01957 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LCAHJLOB_01958 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LCAHJLOB_01960 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
LCAHJLOB_01961 6.5e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
LCAHJLOB_01962 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
LCAHJLOB_01963 5.1e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
LCAHJLOB_01964 2.6e-180 scrR K Transcriptional regulator
LCAHJLOB_01965 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCAHJLOB_01966 4.9e-61 yqhY S protein conserved in bacteria
LCAHJLOB_01967 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCAHJLOB_01968 1.3e-84 comEB 3.5.4.12 F ComE operon protein 2
LCAHJLOB_01969 5.9e-186 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
LCAHJLOB_01971 1.9e-144 V 'abc transporter, ATP-binding protein
LCAHJLOB_01972 8e-32 blpT
LCAHJLOB_01977 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCAHJLOB_01978 3.2e-167 corA P COG0598 Mg2 and Co2 transporters
LCAHJLOB_01979 8.5e-122 XK27_01040 S Protein of unknown function (DUF1129)
LCAHJLOB_01981 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LCAHJLOB_01982 1.6e-80 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LCAHJLOB_01983 1.1e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
LCAHJLOB_01984 3.8e-43 XK27_05745
LCAHJLOB_01985 8.3e-218 mutY L A G-specific adenine glycosylase
LCAHJLOB_01988 7.6e-35
LCAHJLOB_01990 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCAHJLOB_01991 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LCAHJLOB_01992 1.8e-93 cvpA S toxin biosynthetic process
LCAHJLOB_01993 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LCAHJLOB_01994 1.9e-153 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCAHJLOB_01995 6.1e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LCAHJLOB_01996 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LCAHJLOB_01997 7.5e-47 azlD S branched-chain amino acid
LCAHJLOB_01998 2.2e-112 azlC E AzlC protein
LCAHJLOB_01999 6.2e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LCAHJLOB_02000 9e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LCAHJLOB_02001 1.4e-119 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
LCAHJLOB_02002 1.5e-33 ykzG S Belongs to the UPF0356 family
LCAHJLOB_02003 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LCAHJLOB_02004 1.5e-115 pscB M CHAP domain protein
LCAHJLOB_02005 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
LCAHJLOB_02006 8.5e-63 glnR K Transcriptional regulator
LCAHJLOB_02007 2.5e-86 S Fusaric acid resistance protein-like
LCAHJLOB_02008 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LCAHJLOB_02009 3.3e-124
LCAHJLOB_02010 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
LCAHJLOB_02011 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LCAHJLOB_02012 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LCAHJLOB_02013 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LCAHJLOB_02014 4e-142 purR 2.4.2.7 F operon repressor
LCAHJLOB_02015 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
LCAHJLOB_02016 7.9e-169 rmuC S RmuC domain protein
LCAHJLOB_02017 4e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
LCAHJLOB_02018 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LCAHJLOB_02019 9.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LCAHJLOB_02021 2.1e-152 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LCAHJLOB_02022 7.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LCAHJLOB_02023 4e-142 tatD L Hydrolase, tatd
LCAHJLOB_02024 1.7e-70 yccU S CoA-binding protein
LCAHJLOB_02025 2.4e-50 trxA O Belongs to the thioredoxin family
LCAHJLOB_02026 5.1e-142 S Macro domain protein
LCAHJLOB_02027 8.2e-59 L thioesterase
LCAHJLOB_02028 1.6e-49 bta 1.8.1.8 CO cell redox homeostasis
LCAHJLOB_02030 1.6e-123 L Helix-turn-helix domain
LCAHJLOB_02031 1.9e-88 L COG1943 Transposase and inactivated derivatives
LCAHJLOB_02032 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LCAHJLOB_02033 4.9e-103 thiJ-2 3.5.1.124 S DJ-1/PfpI family
LCAHJLOB_02034 6e-303 dnaK O Heat shock 70 kDa protein
LCAHJLOB_02035 5.9e-70 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LCAHJLOB_02036 2.4e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LCAHJLOB_02037 1.1e-98 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
LCAHJLOB_02038 4.8e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LCAHJLOB_02039 5.6e-132 ais G Phosphoglycerate mutase
LCAHJLOB_02040 2.8e-241 XK27_08635 S UPF0210 protein
LCAHJLOB_02041 1e-38 gcvR T UPF0237 protein
LCAHJLOB_02042 1.1e-233 capA M Bacterial capsule synthesis protein
LCAHJLOB_02043 4.6e-149 srtB 3.4.22.70 S Sortase family
LCAHJLOB_02045 1.5e-29 K Helix-turn-helix domain
LCAHJLOB_02046 1.3e-17
LCAHJLOB_02047 1.4e-50 yiiE S Protein of unknown function (DUF1211)
LCAHJLOB_02048 1.6e-16
LCAHJLOB_02049 4.5e-55 cadC K Bacterial regulatory protein, arsR family
LCAHJLOB_02050 2e-101 cadD P cadmium resistance
LCAHJLOB_02051 0.0 ctpC 3.6.3.10, 3.6.3.4 P p-ATPase superfamily P-type ATPase copper transporter
LCAHJLOB_02052 2.6e-40
LCAHJLOB_02053 1.6e-105 L Transposase
LCAHJLOB_02054 1e-31 yegS 2.7.1.107 I lipid kinase activity
LCAHJLOB_02055 9.3e-51 S membrane protein of uknown function UCP014873
LCAHJLOB_02056 1.6e-32 int L DNA integration
LCAHJLOB_02057 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
LCAHJLOB_02058 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LCAHJLOB_02059 5.1e-22 K Transcriptional
LCAHJLOB_02061 7e-153 degV S DegV family
LCAHJLOB_02062 6e-91 yacP S RNA-binding protein containing a PIN domain
LCAHJLOB_02063 1.3e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCAHJLOB_02065 1e-66 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LCAHJLOB_02066 4.9e-254 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LCAHJLOB_02067 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
LCAHJLOB_02068 2.7e-140 S SseB protein N-terminal domain
LCAHJLOB_02069 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LCAHJLOB_02070 9.9e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LCAHJLOB_02071 1.3e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LCAHJLOB_02072 0.0 clpC O Belongs to the ClpA ClpB family
LCAHJLOB_02073 2e-74 ctsR K Belongs to the CtsR family
LCAHJLOB_02074 1.6e-82 S Putative small multi-drug export protein
LCAHJLOB_02075 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LCAHJLOB_02076 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
LCAHJLOB_02077 2.7e-105 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
LCAHJLOB_02078 7.3e-286 ahpF O alkyl hydroperoxide reductase
LCAHJLOB_02080 8.8e-93 S reductase
LCAHJLOB_02081 3.9e-72 badR K Transcriptional regulator, marr family
LCAHJLOB_02082 7.9e-35 XK27_02060 S Transglycosylase associated protein
LCAHJLOB_02083 2.5e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LCAHJLOB_02084 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCAHJLOB_02085 3.6e-49 qacC P COG2076 Membrane transporters of cations and cationic drugs
LCAHJLOB_02086 1e-75 K Transcriptional
LCAHJLOB_02087 7.2e-75
LCAHJLOB_02088 2.1e-216 L Replication initiation factor
LCAHJLOB_02089 3.4e-67
LCAHJLOB_02090 3.5e-28 S Domain of unknown function (DUF3173)
LCAHJLOB_02091 1.4e-204 L Belongs to the 'phage' integrase family
LCAHJLOB_02096 1.9e-07
LCAHJLOB_02099 2.6e-10
LCAHJLOB_02111 3.2e-145 L Integrase core domain protein
LCAHJLOB_02112 1.6e-123 L Helix-turn-helix domain
LCAHJLOB_02113 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LCAHJLOB_02114 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LCAHJLOB_02115 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LCAHJLOB_02116 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LCAHJLOB_02117 3e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCAHJLOB_02118 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LCAHJLOB_02119 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
LCAHJLOB_02120 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCAHJLOB_02121 9.7e-86
LCAHJLOB_02122 7.8e-43 M1-386
LCAHJLOB_02123 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LCAHJLOB_02124 1e-94 F Shikimate kinase
LCAHJLOB_02125 1.3e-102 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
LCAHJLOB_02126 5.3e-104 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LCAHJLOB_02129 3e-14 coiA 3.6.4.12 S Competence protein
LCAHJLOB_02130 8.9e-17 T peptidase
LCAHJLOB_02131 1.4e-148 rarD S Transporter
LCAHJLOB_02132 3.5e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LCAHJLOB_02133 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LCAHJLOB_02134 7.9e-128 yxkH G deacetylase
LCAHJLOB_02135 8.8e-204 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LCAHJLOB_02136 8.2e-126 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LCAHJLOB_02137 3.9e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LCAHJLOB_02138 5.9e-183 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LCAHJLOB_02139 6.7e-136 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
LCAHJLOB_02140 5.5e-71 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
LCAHJLOB_02141 3.1e-139 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LCAHJLOB_02142 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
LCAHJLOB_02143 5.7e-14
LCAHJLOB_02144 7e-229 2.7.13.3 T GHKL domain
LCAHJLOB_02145 5.3e-133 agrA KT response regulator
LCAHJLOB_02146 1.9e-50 L transposase and inactivated derivatives, IS30 family
LCAHJLOB_02147 7.4e-40 L Integrase
LCAHJLOB_02148 2.9e-159 2.7.13.3 T Histidine kinase
LCAHJLOB_02149 3.3e-105 T Transcriptional regulatory protein, C terminal
LCAHJLOB_02150 5.5e-79
LCAHJLOB_02151 1.7e-121 S ABC-2 family transporter protein
LCAHJLOB_02152 2.8e-123 V AAA domain, putative AbiEii toxin, Type IV TA system
LCAHJLOB_02153 0.0 V ABC transporter transmembrane region
LCAHJLOB_02154 6.2e-33 S Coenzyme PQQ synthesis protein D (PqqD)
LCAHJLOB_02155 1.3e-201 6.3.5.4 E Asparagine synthase
LCAHJLOB_02157 2.6e-24 L Integrase core domain protein
LCAHJLOB_02158 3.5e-83 L Transposase
LCAHJLOB_02159 3.1e-07
LCAHJLOB_02160 5.4e-133 agrA KT phosphorelay signal transduction system
LCAHJLOB_02161 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LCAHJLOB_02163 1.2e-09
LCAHJLOB_02164 2.9e-165 K sequence-specific DNA binding
LCAHJLOB_02165 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LCAHJLOB_02166 1.7e-84 yxjI S LURP-one-related
LCAHJLOB_02167 4.3e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
LCAHJLOB_02168 6.7e-119 yrrM 2.1.1.104 S O-Methyltransferase
LCAHJLOB_02169 3.5e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
LCAHJLOB_02170 0.0 pepF E oligoendopeptidase F
LCAHJLOB_02171 5.9e-169 coiA 3.6.4.12 S Competence protein
LCAHJLOB_02172 8.9e-265 S Glucan-binding protein C
LCAHJLOB_02173 2e-108 S CAAX amino terminal protease family protein
LCAHJLOB_02174 4.7e-168 K transcriptional regulator (lysR family)
LCAHJLOB_02175 2.4e-161 S reductase
LCAHJLOB_02176 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCAHJLOB_02180 1.2e-186 phoH T phosphate starvation-inducible protein PhoH
LCAHJLOB_02181 9.4e-130 sip M LysM domain protein
LCAHJLOB_02182 3.7e-34 yozE S Belongs to the UPF0346 family
LCAHJLOB_02183 1.9e-158 cvfB S Protein conserved in bacteria
LCAHJLOB_02184 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LCAHJLOB_02185 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LCAHJLOB_02186 1.5e-209 sptS 2.7.13.3 T Histidine kinase
LCAHJLOB_02187 9.2e-116 T response regulator
LCAHJLOB_02188 1.3e-111 2.7.6.5 S Region found in RelA / SpoT proteins
LCAHJLOB_02189 1.3e-111 K Acetyltransferase (GNAT) family
LCAHJLOB_02190 0.0 lmrA2 V abc transporter atp-binding protein
LCAHJLOB_02191 5.5e-309 lmrA1 V abc transporter atp-binding protein
LCAHJLOB_02192 4.4e-74 K DNA-binding transcription factor activity
LCAHJLOB_02193 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LCAHJLOB_02194 2.1e-267 S Psort location CytoplasmicMembrane, score
LCAHJLOB_02195 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
LCAHJLOB_02196 1e-153 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
LCAHJLOB_02197 1.8e-43 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
LCAHJLOB_02198 2.4e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
LCAHJLOB_02199 5e-26 U response to pH
LCAHJLOB_02200 0.0 yfmR S abc transporter atp-binding protein
LCAHJLOB_02201 6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LCAHJLOB_02202 2.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LCAHJLOB_02203 2.4e-145 XK27_08360 S EDD domain protein, DegV family
LCAHJLOB_02204 5e-63 WQ51_03320 S cog cog4835
LCAHJLOB_02205 1.1e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCAHJLOB_02206 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LCAHJLOB_02207 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LCAHJLOB_02208 9.6e-92 2.3.1.128 K acetyltransferase
LCAHJLOB_02209 2.8e-254 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
LCAHJLOB_02210 1.8e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
LCAHJLOB_02211 2.2e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LCAHJLOB_02212 1.4e-209 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
LCAHJLOB_02214 1.2e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LCAHJLOB_02215 2.6e-255 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCAHJLOB_02216 0.0 fruA 2.7.1.202 G phosphotransferase system
LCAHJLOB_02217 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LCAHJLOB_02218 3e-112 fruR K transcriptional
LCAHJLOB_02219 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
LCAHJLOB_02220 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LCAHJLOB_02221 2e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LCAHJLOB_02222 1.7e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LCAHJLOB_02223 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LCAHJLOB_02224 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LCAHJLOB_02225 1.6e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LCAHJLOB_02226 1.3e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LCAHJLOB_02227 1.1e-125 IQ reductase
LCAHJLOB_02228 1e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LCAHJLOB_02229 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
LCAHJLOB_02230 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCAHJLOB_02231 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCAHJLOB_02232 5.2e-72 marR K Transcriptional regulator, MarR family
LCAHJLOB_02233 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
LCAHJLOB_02234 3.8e-111 S HAD hydrolase, family IA, variant 3
LCAHJLOB_02235 1.8e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
LCAHJLOB_02236 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
LCAHJLOB_02237 1.7e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCAHJLOB_02238 1.6e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
LCAHJLOB_02239 7.8e-102 ygaC J Belongs to the UPF0374 family
LCAHJLOB_02240 9.2e-99 S Domain of unknown function (DUF1803)
LCAHJLOB_02241 3.1e-162 ppaC 3.6.1.1 C inorganic pyrophosphatase
LCAHJLOB_02248 9.7e-228 L Transposase
LCAHJLOB_02249 5.4e-192 mccF V LD-carboxypeptidase
LCAHJLOB_02250 2.8e-120 liaI S membrane
LCAHJLOB_02251 5.7e-74 XK27_02470 K LytTr DNA-binding domain
LCAHJLOB_02252 6.2e-310 KT response to antibiotic
LCAHJLOB_02253 1.7e-109 yebC M Membrane
LCAHJLOB_02254 6.8e-259 XK27_03190 S hydrolases of the HAD superfamily
LCAHJLOB_02255 3e-170 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LCAHJLOB_02257 2.9e-31 yozG K Transcriptional regulator
LCAHJLOB_02260 1e-224 L the current gene model (or a revised gene model) may contain a frame shift

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)