ORF_ID e_value Gene_name EC_number CAZy COGs Description
HKPMIKFJ_00001 5.8e-141 U Binding-protein-dependent transport system inner membrane component
HKPMIKFJ_00002 7.7e-152 U Binding-protein-dependent transport system inner membrane component
HKPMIKFJ_00003 3.3e-247 G Bacterial extracellular solute-binding protein
HKPMIKFJ_00004 3.6e-213 P Belongs to the ABC transporter superfamily
HKPMIKFJ_00005 5.3e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
HKPMIKFJ_00006 1.9e-259 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKPMIKFJ_00007 4.2e-103 pncA Q Isochorismatase family
HKPMIKFJ_00008 2.4e-44 L Transposase and inactivated derivatives, IS30 family
HKPMIKFJ_00009 1.2e-160 L Integrase core domain
HKPMIKFJ_00010 4.7e-167 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HKPMIKFJ_00011 5.7e-91 perR P Belongs to the Fur family
HKPMIKFJ_00012 1.9e-113 S VIT family
HKPMIKFJ_00013 2.3e-117 S membrane
HKPMIKFJ_00014 1.2e-294 E amino acid
HKPMIKFJ_00015 8.5e-78 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKPMIKFJ_00016 1.9e-197 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HKPMIKFJ_00017 7.4e-177 sepS16B
HKPMIKFJ_00018 2.5e-124
HKPMIKFJ_00019 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HKPMIKFJ_00020 1.8e-43
HKPMIKFJ_00021 8e-31
HKPMIKFJ_00022 5e-57
HKPMIKFJ_00023 1.2e-152 pstS P Phosphate
HKPMIKFJ_00024 1e-168 pstC P probably responsible for the translocation of the substrate across the membrane
HKPMIKFJ_00025 1e-143 pstA P Phosphate transport system permease protein PstA
HKPMIKFJ_00026 4.8e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKPMIKFJ_00027 7.8e-202 potD P ABC transporter
HKPMIKFJ_00028 2e-133 potC P ABC transporter permease
HKPMIKFJ_00029 5e-148 potB P ABC transporter permease
HKPMIKFJ_00030 3.1e-209 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKPMIKFJ_00033 4.9e-43 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
HKPMIKFJ_00034 9.4e-178 hoxN U High-affinity nickel-transport protein
HKPMIKFJ_00035 2.2e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HKPMIKFJ_00036 2.3e-148 larE S NAD synthase
HKPMIKFJ_00037 6.6e-229 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HKPMIKFJ_00038 2.1e-132 cpmA S AIR carboxylase
HKPMIKFJ_00039 2.1e-238 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HKPMIKFJ_00040 1.7e-125 K Crp-like helix-turn-helix domain
HKPMIKFJ_00041 1.2e-282 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HKPMIKFJ_00042 1.5e-67 yqeB S Pyrimidine dimer DNA glycosylase
HKPMIKFJ_00043 3.4e-64 S Protein of unknown function (DUF1722)
HKPMIKFJ_00044 1.3e-153 1.1.1.2, 1.1.1.307 C Aldo keto reductase
HKPMIKFJ_00045 8.3e-154 degV S Uncharacterised protein, DegV family COG1307
HKPMIKFJ_00046 5.1e-251 yjjP S Putative threonine/serine exporter
HKPMIKFJ_00048 4.7e-211 natB CP ABC-2 family transporter protein
HKPMIKFJ_00049 1.8e-167 natA S ABC transporter, ATP-binding protein
HKPMIKFJ_00050 1.6e-247 pbuX F xanthine permease
HKPMIKFJ_00051 3.2e-24
HKPMIKFJ_00052 3e-187 ansA 3.5.1.1 EJ Asparaginase
HKPMIKFJ_00053 3e-215
HKPMIKFJ_00054 2.3e-30
HKPMIKFJ_00056 1.1e-08
HKPMIKFJ_00057 1.9e-59
HKPMIKFJ_00058 2.7e-120 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKPMIKFJ_00059 7.5e-115 P Cobalt transport protein
HKPMIKFJ_00060 1.5e-256 P ABC transporter
HKPMIKFJ_00061 2.2e-94 S ABC transporter permease
HKPMIKFJ_00062 9.8e-169 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKPMIKFJ_00063 1.1e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKPMIKFJ_00064 4.3e-126 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HKPMIKFJ_00065 1.2e-55 S LuxR family transcriptional regulator
HKPMIKFJ_00066 1.2e-135 S Uncharacterized protein conserved in bacteria (DUF2087)
HKPMIKFJ_00067 6.8e-73 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HKPMIKFJ_00068 1.6e-233 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKPMIKFJ_00069 9.9e-149 S Alpha/beta hydrolase of unknown function (DUF915)
HKPMIKFJ_00070 2.4e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HKPMIKFJ_00071 9.7e-86
HKPMIKFJ_00072 1.6e-07 yvlA
HKPMIKFJ_00073 2.7e-177 iunH2 3.2.2.1, 3.2.2.8 F nucleoside hydrolase
HKPMIKFJ_00074 1e-190 S Protease prsW family
HKPMIKFJ_00075 6.8e-144 S Alpha/beta hydrolase of unknown function (DUF915)
HKPMIKFJ_00076 3.5e-180 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HKPMIKFJ_00077 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKPMIKFJ_00078 9e-124 pgm3 G phosphoglycerate mutase family
HKPMIKFJ_00079 1.3e-75 yjcF K protein acetylation
HKPMIKFJ_00080 1.5e-61 iap CBM50 M NlpC P60 family
HKPMIKFJ_00081 2.7e-82 merR K MerR family regulatory protein
HKPMIKFJ_00082 1.6e-91 K Transcriptional regulator PadR-like family
HKPMIKFJ_00083 1.4e-254 ydiC1 EGP Major facilitator Superfamily
HKPMIKFJ_00084 0.0 ydgH S MMPL family
HKPMIKFJ_00085 7.1e-15
HKPMIKFJ_00086 1.3e-134 IQ reductase
HKPMIKFJ_00087 9e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKPMIKFJ_00088 1.8e-181 S DUF218 domain
HKPMIKFJ_00089 4.5e-109 NU mannosyl-glycoprotein
HKPMIKFJ_00090 4.2e-242 pbpX1 V SH3-like domain
HKPMIKFJ_00091 1.5e-127 terC P integral membrane protein, YkoY family
HKPMIKFJ_00092 3.6e-157 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HKPMIKFJ_00094 2.2e-137 XK27_08845 S ABC transporter, ATP-binding protein
HKPMIKFJ_00095 3.9e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HKPMIKFJ_00096 2.9e-179 XK27_08835 S ABC transporter
HKPMIKFJ_00097 4.5e-163 degV S Uncharacterised protein, DegV family COG1307
HKPMIKFJ_00098 2.8e-166 XK27_00670 S ABC transporter
HKPMIKFJ_00099 1.1e-167 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HKPMIKFJ_00100 1.1e-119 cmpC S ATPases associated with a variety of cellular activities
HKPMIKFJ_00101 1.6e-11 M domain protein
HKPMIKFJ_00103 2e-126 XK27_07075 S CAAX protease self-immunity
HKPMIKFJ_00104 2e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKPMIKFJ_00105 6.7e-295 S ABC transporter, ATP-binding protein
HKPMIKFJ_00106 3.9e-86 M ErfK YbiS YcfS YnhG
HKPMIKFJ_00108 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HKPMIKFJ_00109 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKPMIKFJ_00110 1.4e-240 yfnA E Amino Acid
HKPMIKFJ_00111 7.1e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HKPMIKFJ_00112 2.3e-75 gmk2 2.7.4.8 F Guanylate kinase
HKPMIKFJ_00113 4.7e-79 zur P Belongs to the Fur family
HKPMIKFJ_00114 5.3e-13 3.2.1.14 GH18
HKPMIKFJ_00115 8.9e-170
HKPMIKFJ_00116 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKPMIKFJ_00117 1.2e-149 glnH ET ABC transporter substrate-binding protein
HKPMIKFJ_00118 1.1e-110 gluC P ABC transporter permease
HKPMIKFJ_00119 2.1e-109 glnP P ABC transporter permease
HKPMIKFJ_00120 3.9e-224 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKPMIKFJ_00121 3.1e-303 oppA E ABC transporter, substratebinding protein
HKPMIKFJ_00122 5.3e-295 oppA E ABC transporter, substratebinding protein
HKPMIKFJ_00123 2.2e-152 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKPMIKFJ_00124 9.8e-186 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKPMIKFJ_00125 3.8e-204 oppD P Belongs to the ABC transporter superfamily
HKPMIKFJ_00126 4.4e-180 oppF P Belongs to the ABC transporter superfamily
HKPMIKFJ_00127 1.5e-118 G phosphoglycerate mutase
HKPMIKFJ_00128 1e-289 yjbQ P TrkA C-terminal domain protein
HKPMIKFJ_00129 0.0 helD 3.6.4.12 L DNA helicase
HKPMIKFJ_00130 7e-175 coaA 2.7.1.33 F Pantothenic acid kinase
HKPMIKFJ_00131 2.7e-100 aacA4_1 4.1.1.17 K acetyltransferase
HKPMIKFJ_00132 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HKPMIKFJ_00133 2.9e-57 bipA 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Leucine-rich repeat (LRR) protein
HKPMIKFJ_00134 0.0 rafA 3.2.1.22 G alpha-galactosidase
HKPMIKFJ_00135 2.8e-72 S Iron-sulphur cluster biosynthesis
HKPMIKFJ_00136 0.0 pepN 3.4.11.2 E aminopeptidase
HKPMIKFJ_00137 1.4e-263 arcD E Arginine ornithine antiporter
HKPMIKFJ_00138 1.5e-277 pipD E Dipeptidase
HKPMIKFJ_00139 1.3e-91 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HKPMIKFJ_00140 9e-69 K Transcriptional regulator
HKPMIKFJ_00141 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HKPMIKFJ_00142 3.4e-296 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HKPMIKFJ_00143 2e-236 lacY G Oligosaccharide H symporter
HKPMIKFJ_00144 4.6e-201 abf G Belongs to the glycosyl hydrolase 43 family
HKPMIKFJ_00145 2.9e-146 K transcriptional regulator, ArsR family
HKPMIKFJ_00146 8.7e-177 araR K Transcriptional regulator
HKPMIKFJ_00147 5.8e-213 melB G symporter
HKPMIKFJ_00148 2.5e-10
HKPMIKFJ_00149 6.5e-255 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HKPMIKFJ_00150 8.8e-72 K sequence-specific DNA binding
HKPMIKFJ_00151 2.4e-216 G symporter
HKPMIKFJ_00152 2.7e-131 yisR K helix_turn_helix, arabinose operon control protein
HKPMIKFJ_00153 0.0
HKPMIKFJ_00154 4.1e-263 araB 2.7.1.16 G carbohydrate kinase FGGY
HKPMIKFJ_00155 9.2e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKPMIKFJ_00156 2.3e-278 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HKPMIKFJ_00157 1.7e-86 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HKPMIKFJ_00160 2e-49 S Glycine cleavage H-protein
HKPMIKFJ_00161 1.4e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HKPMIKFJ_00162 4e-139 yejC S Protein of unknown function (DUF1003)
HKPMIKFJ_00163 2.4e-104 3.2.2.20 K acetyltransferase
HKPMIKFJ_00164 9.6e-89 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HKPMIKFJ_00165 1e-69
HKPMIKFJ_00166 2.8e-216 EGP Major facilitator Superfamily
HKPMIKFJ_00167 1.3e-232 pyrP F Permease
HKPMIKFJ_00168 1.4e-48 azlD S Branched-chain amino acid transport protein (AzlD)
HKPMIKFJ_00169 3.7e-107 azlC E branched-chain amino acid
HKPMIKFJ_00170 1e-37 yyaN K MerR HTH family regulatory protein
HKPMIKFJ_00171 6.2e-102 S Domain of unknown function (DUF4811)
HKPMIKFJ_00172 6.7e-268 lmrB EGP Major facilitator Superfamily
HKPMIKFJ_00173 9.3e-77 merR K MerR HTH family regulatory protein
HKPMIKFJ_00174 4.3e-103 K Acetyltransferase (GNAT) domain
HKPMIKFJ_00175 1.2e-158 czcD P cation diffusion facilitator family transporter
HKPMIKFJ_00176 5.3e-121 sirR K iron dependent repressor
HKPMIKFJ_00177 3.1e-120 thrE S Putative threonine/serine exporter
HKPMIKFJ_00178 1.2e-71 S Threonine/Serine exporter, ThrE
HKPMIKFJ_00179 1e-119 lssY 3.6.1.27 I phosphatase
HKPMIKFJ_00180 2.6e-130 I alpha/beta hydrolase fold
HKPMIKFJ_00181 1.4e-24 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKPMIKFJ_00182 1.8e-276 lysP E amino acid
HKPMIKFJ_00183 9.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HKPMIKFJ_00184 2e-212 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKPMIKFJ_00193 9.9e-77 ctsR K Belongs to the CtsR family
HKPMIKFJ_00194 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKPMIKFJ_00195 4.7e-103 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_00196 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKPMIKFJ_00197 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKPMIKFJ_00198 4.5e-112 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HKPMIKFJ_00199 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKPMIKFJ_00200 3.2e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKPMIKFJ_00201 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKPMIKFJ_00202 2e-231 mepA V MATE efflux family protein
HKPMIKFJ_00203 8.9e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
HKPMIKFJ_00204 6.1e-117 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKPMIKFJ_00205 3.2e-107 rplD J Forms part of the polypeptide exit tunnel
HKPMIKFJ_00206 2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKPMIKFJ_00207 6e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKPMIKFJ_00208 1.8e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKPMIKFJ_00209 2.4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKPMIKFJ_00210 5.1e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKPMIKFJ_00211 7.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKPMIKFJ_00212 4.8e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HKPMIKFJ_00213 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKPMIKFJ_00214 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKPMIKFJ_00215 1.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKPMIKFJ_00216 2.1e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKPMIKFJ_00217 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKPMIKFJ_00218 3.9e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKPMIKFJ_00219 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKPMIKFJ_00220 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKPMIKFJ_00221 3.8e-24 rpmD J Ribosomal protein L30
HKPMIKFJ_00222 1.9e-69 rplO J Binds to the 23S rRNA
HKPMIKFJ_00223 1.2e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKPMIKFJ_00224 3.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKPMIKFJ_00225 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKPMIKFJ_00226 1.3e-60 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKPMIKFJ_00227 7.5e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKPMIKFJ_00228 9.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKPMIKFJ_00229 7.4e-62 rplQ J Ribosomal protein L17
HKPMIKFJ_00230 4.1e-150 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKPMIKFJ_00231 9.2e-161 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKPMIKFJ_00232 6.1e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKPMIKFJ_00233 4.2e-152 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKPMIKFJ_00234 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKPMIKFJ_00235 1.4e-63 rpsI J Belongs to the universal ribosomal protein uS9 family
HKPMIKFJ_00236 4.1e-194 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKPMIKFJ_00237 3.1e-240 ktrB P Potassium uptake protein
HKPMIKFJ_00238 1.8e-116 ktrA P domain protein
HKPMIKFJ_00239 1.2e-196 asnA 6.3.1.1 F aspartate--ammonia ligase
HKPMIKFJ_00240 1.7e-252 yfnA E Amino Acid
HKPMIKFJ_00241 8.5e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HKPMIKFJ_00242 1.2e-157 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HKPMIKFJ_00243 1.4e-144 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKPMIKFJ_00244 1.3e-179 pdxB EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKPMIKFJ_00245 3.9e-281 cydA 1.10.3.14 C ubiquinol oxidase
HKPMIKFJ_00246 1.1e-173 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HKPMIKFJ_00247 3.1e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKPMIKFJ_00248 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKPMIKFJ_00249 2.3e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKPMIKFJ_00250 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HKPMIKFJ_00251 5.1e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKPMIKFJ_00252 2.5e-214 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKPMIKFJ_00253 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HKPMIKFJ_00254 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKPMIKFJ_00255 1.1e-193 camS S sex pheromone
HKPMIKFJ_00256 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKPMIKFJ_00257 7.2e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKPMIKFJ_00258 6.5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKPMIKFJ_00259 1.3e-185 yegS 2.7.1.107 G Lipid kinase
HKPMIKFJ_00260 1.8e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKPMIKFJ_00261 2.5e-42 eutP E Ethanolamine utilisation - propanediol utilisation
HKPMIKFJ_00262 9.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HKPMIKFJ_00263 1.4e-125 K helix_turn_helix, arabinose operon control protein
HKPMIKFJ_00264 5.2e-41 pduA_4 CQ BMC
HKPMIKFJ_00265 1.2e-129 pduB E BMC
HKPMIKFJ_00266 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HKPMIKFJ_00267 8.5e-128 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HKPMIKFJ_00268 1.1e-89 pduE 4.2.1.28 Q Dehydratase small subunit
HKPMIKFJ_00269 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
HKPMIKFJ_00270 1.3e-57 pduH S Dehydratase medium subunit
HKPMIKFJ_00271 4.5e-80 pduK CQ BMC
HKPMIKFJ_00272 4.9e-42 pduA_4 CQ BMC
HKPMIKFJ_00273 6.1e-114 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HKPMIKFJ_00274 3e-90 S Putative propanediol utilisation
HKPMIKFJ_00275 3e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HKPMIKFJ_00276 7.6e-103 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HKPMIKFJ_00277 5.2e-81 pduO S Haem-degrading
HKPMIKFJ_00278 3e-265 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HKPMIKFJ_00279 1.8e-209 pduQ C Iron-containing alcohol dehydrogenase
HKPMIKFJ_00280 7e-220 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKPMIKFJ_00281 1.7e-54 pduU E BMC
HKPMIKFJ_00282 1.2e-191 C Oxidoreductase
HKPMIKFJ_00283 6.6e-142 3.1.3.48 T Pfam:Y_phosphatase3C
HKPMIKFJ_00284 8.7e-57 K Helix-turn-helix XRE-family like proteins
HKPMIKFJ_00285 2e-36 cro K Helix-turn-helix XRE-family like proteins
HKPMIKFJ_00286 1.3e-120 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKPMIKFJ_00287 6.5e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKPMIKFJ_00288 1.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HKPMIKFJ_00289 1.2e-172 deoR K sugar-binding domain protein
HKPMIKFJ_00290 1.3e-238 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HKPMIKFJ_00291 4.9e-293 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HKPMIKFJ_00292 2.5e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKPMIKFJ_00293 4.1e-248 fucP G Major Facilitator Superfamily
HKPMIKFJ_00294 2.8e-233 potE E amino acid
HKPMIKFJ_00295 3.7e-209 gntP EG Gluconate
HKPMIKFJ_00296 5.6e-302 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
HKPMIKFJ_00297 4.4e-147 gntR K rpiR family
HKPMIKFJ_00298 2.5e-138 lys M Glycosyl hydrolases family 25
HKPMIKFJ_00299 5.7e-64 S Domain of unknown function (DUF4828)
HKPMIKFJ_00300 3.3e-186 mocA S Oxidoreductase
HKPMIKFJ_00301 5.8e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
HKPMIKFJ_00303 1.6e-76 T Universal stress protein family
HKPMIKFJ_00304 4.1e-232 gntP EG Gluconate
HKPMIKFJ_00305 4.2e-159 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
HKPMIKFJ_00306 5.9e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKPMIKFJ_00307 1.8e-156 S Nuclease-related domain
HKPMIKFJ_00308 9e-159 yihY S Belongs to the UPF0761 family
HKPMIKFJ_00309 1e-78 fld C Flavodoxin
HKPMIKFJ_00310 8e-143 recX 2.4.1.337 GT4 S Regulatory protein RecX
HKPMIKFJ_00311 3e-215 pbpX2 V Beta-lactamase
HKPMIKFJ_00312 5.6e-39 S Bacteriocin-protection, YdeI or OmpD-Associated
HKPMIKFJ_00313 4.4e-108 ygaC J Belongs to the UPF0374 family
HKPMIKFJ_00314 3.4e-179 yueF S AI-2E family transporter
HKPMIKFJ_00315 2.6e-76 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HKPMIKFJ_00316 5.2e-151
HKPMIKFJ_00317 0.0 2.7.8.12 M glycerophosphotransferase
HKPMIKFJ_00318 1.5e-87
HKPMIKFJ_00319 6.5e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKPMIKFJ_00320 7.3e-121 XK27_00720 S Leucine-rich repeat (LRR) protein
HKPMIKFJ_00321 1.4e-131 XK27_00720 S Leucine-rich repeat (LRR) protein
HKPMIKFJ_00322 3.7e-257 nox 1.6.3.4 C NADH oxidase
HKPMIKFJ_00323 2.5e-280 pipD E Dipeptidase
HKPMIKFJ_00324 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HKPMIKFJ_00325 1.1e-200 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HKPMIKFJ_00326 0.0 clpE O Belongs to the ClpA ClpB family
HKPMIKFJ_00327 4.5e-30
HKPMIKFJ_00328 7.2e-40 ptsH G phosphocarrier protein HPR
HKPMIKFJ_00329 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKPMIKFJ_00330 6.1e-224 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HKPMIKFJ_00331 1e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
HKPMIKFJ_00332 1.6e-183 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKPMIKFJ_00333 4.3e-36 ykuJ S Protein of unknown function (DUF1797)
HKPMIKFJ_00334 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKPMIKFJ_00335 6.7e-156 hipB K Helix-turn-helix
HKPMIKFJ_00336 1.8e-118 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HKPMIKFJ_00337 7.5e-70 yeaO S Protein of unknown function, DUF488
HKPMIKFJ_00338 1.5e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S HAD-hyrolase-like
HKPMIKFJ_00339 2e-77 usp1 T Universal stress protein family
HKPMIKFJ_00340 1.4e-263 U Belongs to the BCCT transporter (TC 2.A.15) family
HKPMIKFJ_00341 2.7e-114 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HKPMIKFJ_00342 2.5e-83 S 3-demethylubiquinone-9 3-methyltransferase
HKPMIKFJ_00343 7.9e-143 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKPMIKFJ_00344 6.6e-84
HKPMIKFJ_00345 3.2e-239 codA 3.5.4.1 F cytosine deaminase
HKPMIKFJ_00346 4.9e-45
HKPMIKFJ_00347 9.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKPMIKFJ_00348 8.9e-18
HKPMIKFJ_00349 7.9e-123 yrkL S Flavodoxin-like fold
HKPMIKFJ_00351 1.1e-29
HKPMIKFJ_00353 1e-37 S Cytochrome B5
HKPMIKFJ_00354 2.1e-31 cspC K Cold shock protein
HKPMIKFJ_00355 1.6e-106 XK27_00220 S Dienelactone hydrolase family
HKPMIKFJ_00356 4.4e-52
HKPMIKFJ_00357 1.1e-219 mutY L A G-specific adenine glycosylase
HKPMIKFJ_00358 4.7e-299 E Bacterial extracellular solute-binding proteins, family 5 Middle
HKPMIKFJ_00359 0.0 pelX M domain, Protein
HKPMIKFJ_00360 4.8e-51
HKPMIKFJ_00361 3.3e-189 6.3.1.20 H Lipoate-protein ligase
HKPMIKFJ_00362 4.5e-64 gcvH E glycine cleavage
HKPMIKFJ_00363 3.3e-183 tas C Aldo/keto reductase family
HKPMIKFJ_00364 1e-31
HKPMIKFJ_00365 2.1e-177 EG EamA-like transporter family
HKPMIKFJ_00366 2.1e-112 metI P ABC transporter permease
HKPMIKFJ_00367 2e-194 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKPMIKFJ_00368 1e-145 P Belongs to the nlpA lipoprotein family
HKPMIKFJ_00369 4.4e-100 tag 3.2.2.20 L glycosylase
HKPMIKFJ_00370 0.0 E ABC transporter, substratebinding protein
HKPMIKFJ_00372 0.0 3.2.1.21 GH3 G hydrolase, family 3
HKPMIKFJ_00373 1.5e-191 pva1 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HKPMIKFJ_00374 1.6e-292 sbcC L Putative exonuclease SbcCD, C subunit
HKPMIKFJ_00375 2.8e-210 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKPMIKFJ_00376 3.9e-104 tag 3.2.2.20 L glycosylase
HKPMIKFJ_00377 1.1e-146 S Zinc-dependent metalloprotease
HKPMIKFJ_00378 2.1e-166 XK27_00880 3.5.1.28 M hydrolase, family 25
HKPMIKFJ_00379 1.3e-204 G Glycosyl hydrolases family 8
HKPMIKFJ_00380 8.6e-56 yphJ 4.1.1.44 S decarboxylase
HKPMIKFJ_00381 5.6e-79 yphH S Cupin domain
HKPMIKFJ_00382 2.9e-75 K helix_turn_helix, mercury resistance
HKPMIKFJ_00383 2e-100 yobS K Bacterial regulatory proteins, tetR family
HKPMIKFJ_00384 1.2e-09 K MarR family
HKPMIKFJ_00385 1.9e-223
HKPMIKFJ_00386 2.4e-158 dkgB S reductase
HKPMIKFJ_00387 3.3e-201 EGP Major facilitator Superfamily
HKPMIKFJ_00388 6.7e-194 EGP Major facilitator Superfamily
HKPMIKFJ_00389 2.2e-134 C Oxidoreductase
HKPMIKFJ_00390 3.2e-40 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HKPMIKFJ_00391 9e-60 K helix_turn_helix, arabinose operon control protein
HKPMIKFJ_00392 1.5e-52 S Domain of unknown function (DUF4430)
HKPMIKFJ_00393 3.8e-177 U FFAT motif binding
HKPMIKFJ_00394 1.4e-113 S ECF-type riboflavin transporter, S component
HKPMIKFJ_00395 9.2e-295 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
HKPMIKFJ_00396 9.1e-156 P ABC-type cobalt transport system permease component CbiQ and related transporters
HKPMIKFJ_00397 1.3e-67
HKPMIKFJ_00398 2.8e-94 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKPMIKFJ_00399 3e-281 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HKPMIKFJ_00400 2.5e-158 K LysR substrate binding domain
HKPMIKFJ_00401 2.3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKPMIKFJ_00402 6.2e-294 epsA I PAP2 superfamily
HKPMIKFJ_00403 1e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
HKPMIKFJ_00404 9.9e-109 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKPMIKFJ_00405 0.0 lmrA 3.6.3.44 V ABC transporter
HKPMIKFJ_00406 2.4e-95 rmaB K Transcriptional regulator, MarR family
HKPMIKFJ_00407 5.3e-114 S membrane transporter protein
HKPMIKFJ_00408 2.4e-136 3.1.3.48 T Tyrosine phosphatase family
HKPMIKFJ_00409 9.6e-122
HKPMIKFJ_00410 1.1e-124 skfE V ATPases associated with a variety of cellular activities
HKPMIKFJ_00411 7.2e-62 yvoA_1 K Transcriptional regulator, GntR family
HKPMIKFJ_00412 1.5e-172 3.5.2.6 V Beta-lactamase enzyme family
HKPMIKFJ_00413 4.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HKPMIKFJ_00414 1.1e-128 S haloacid dehalogenase-like hydrolase
HKPMIKFJ_00415 1.1e-95 bcr1 EGP Major facilitator Superfamily
HKPMIKFJ_00416 3.5e-90 bcr1 EGP Major facilitator Superfamily
HKPMIKFJ_00417 6.6e-145 S Sucrose-6F-phosphate phosphohydrolase
HKPMIKFJ_00418 1.8e-155 map 3.4.11.18 E Methionine Aminopeptidase
HKPMIKFJ_00419 2.2e-93
HKPMIKFJ_00421 6.6e-128 ydfG S KR domain
HKPMIKFJ_00422 4.4e-64 hxlR K HxlR-like helix-turn-helix
HKPMIKFJ_00423 7.4e-60 asp2 S Asp23 family, cell envelope-related function
HKPMIKFJ_00424 3.6e-70 asp S Asp23 family, cell envelope-related function
HKPMIKFJ_00425 5.9e-25
HKPMIKFJ_00426 1.4e-90
HKPMIKFJ_00427 4.4e-18 S Transglycosylase associated protein
HKPMIKFJ_00428 4.2e-156
HKPMIKFJ_00429 1.9e-270 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HKPMIKFJ_00430 1.7e-181 chaT1 U Major Facilitator Superfamily
HKPMIKFJ_00431 2.9e-94 laaE K Transcriptional regulator PadR-like family
HKPMIKFJ_00432 3e-66 lysM M LysM domain
HKPMIKFJ_00434 6.8e-95 I NUDIX domain
HKPMIKFJ_00435 1.1e-113 yviA S Protein of unknown function (DUF421)
HKPMIKFJ_00436 3.7e-73 S Protein of unknown function (DUF3290)
HKPMIKFJ_00437 2.5e-161 ropB K Helix-turn-helix XRE-family like proteins
HKPMIKFJ_00438 5.4e-202 EGP Major facilitator Superfamily
HKPMIKFJ_00439 3.6e-249 gshR 1.8.1.7 C Glutathione reductase
HKPMIKFJ_00440 9.1e-36 ygbF S Sugar efflux transporter for intercellular exchange
HKPMIKFJ_00442 4.9e-197 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKPMIKFJ_00443 1e-35
HKPMIKFJ_00444 2.2e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
HKPMIKFJ_00445 2e-231 gntT EG Citrate transporter
HKPMIKFJ_00446 2e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HKPMIKFJ_00447 5.5e-107 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase HUMPS family
HKPMIKFJ_00448 3.2e-87 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M sugar phosphate isomerase involved in capsule formation
HKPMIKFJ_00449 5.2e-176 kdgR K helix_turn _helix lactose operon repressor
HKPMIKFJ_00450 1.3e-51
HKPMIKFJ_00451 1.8e-83
HKPMIKFJ_00452 0.0 helD 3.6.4.12 L DNA helicase
HKPMIKFJ_00453 1.2e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKPMIKFJ_00454 9.7e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKPMIKFJ_00455 9.1e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HKPMIKFJ_00456 4.9e-179
HKPMIKFJ_00457 1.2e-129 cobB K SIR2 family
HKPMIKFJ_00458 9.4e-50
HKPMIKFJ_00459 5.8e-160 yunF F Protein of unknown function DUF72
HKPMIKFJ_00460 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKPMIKFJ_00461 1.8e-147 tatD L hydrolase, TatD family
HKPMIKFJ_00462 4.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKPMIKFJ_00463 1.3e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKPMIKFJ_00464 4.3e-36 veg S Biofilm formation stimulator VEG
HKPMIKFJ_00465 1.3e-162 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKPMIKFJ_00466 8.4e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
HKPMIKFJ_00467 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
HKPMIKFJ_00468 2.8e-260 xylP G MFS/sugar transport protein
HKPMIKFJ_00469 3.5e-208 xylR GK ROK family
HKPMIKFJ_00470 7e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKPMIKFJ_00471 6.7e-162 2.7.1.2 GK ROK family
HKPMIKFJ_00472 1.7e-87
HKPMIKFJ_00474 6.5e-54 V Transport permease protein
HKPMIKFJ_00475 7.8e-88 V ABC transporter
HKPMIKFJ_00476 1.1e-85 KTV abc transporter atp-binding protein
HKPMIKFJ_00477 9.6e-154 S Prolyl oligopeptidase family
HKPMIKFJ_00478 8.9e-170 znuA P Belongs to the bacterial solute-binding protein 9 family
HKPMIKFJ_00479 1.8e-130 fhuC P ABC transporter
HKPMIKFJ_00480 1.4e-131 znuB U ABC 3 transport family
HKPMIKFJ_00483 1.5e-144 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HKPMIKFJ_00484 2.5e-216 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKPMIKFJ_00485 5.5e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKPMIKFJ_00486 3.7e-55 S Domain of unknown function (DUF3899)
HKPMIKFJ_00487 2e-68 racA K helix_turn_helix, mercury resistance
HKPMIKFJ_00488 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
HKPMIKFJ_00489 0.0 xpkA 4.1.2.22, 4.1.2.9 G Phosphoketolase
HKPMIKFJ_00490 1.3e-143 yxeH S hydrolase
HKPMIKFJ_00491 1.3e-265 ywfO S HD domain protein
HKPMIKFJ_00492 7.8e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HKPMIKFJ_00493 2.2e-78 ywiB S Domain of unknown function (DUF1934)
HKPMIKFJ_00494 5.8e-54 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKPMIKFJ_00495 1.3e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKPMIKFJ_00496 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HKPMIKFJ_00498 3.5e-223
HKPMIKFJ_00499 3.9e-72 K Transcriptional regulator
HKPMIKFJ_00500 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HKPMIKFJ_00501 1e-128 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HKPMIKFJ_00502 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HKPMIKFJ_00503 2.8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKPMIKFJ_00504 4.3e-42 rpmE2 J Ribosomal protein L31
HKPMIKFJ_00505 8.7e-117 srtA 3.4.22.70 M sortase family
HKPMIKFJ_00506 6.4e-17 S WxL domain surface cell wall-binding
HKPMIKFJ_00507 2.8e-10 S WxL domain surface cell wall-binding
HKPMIKFJ_00508 6e-279
HKPMIKFJ_00509 7.5e-15 E Zn peptidase
HKPMIKFJ_00510 8.6e-19
HKPMIKFJ_00512 5e-20 S AAA ATPase domain
HKPMIKFJ_00514 6.6e-101
HKPMIKFJ_00515 1.5e-32
HKPMIKFJ_00516 8.9e-60 K HxlR-like helix-turn-helix
HKPMIKFJ_00517 5.9e-39
HKPMIKFJ_00518 1.9e-82
HKPMIKFJ_00519 6.3e-44
HKPMIKFJ_00520 1.3e-111 GM NmrA-like family
HKPMIKFJ_00521 7.4e-152 5.4.2.7 G Metalloenzyme superfamily
HKPMIKFJ_00522 2e-225 nupG F Nucleoside
HKPMIKFJ_00523 9.8e-215 pbuO_1 S Permease family
HKPMIKFJ_00524 2.8e-168 rihC 3.2.2.1, 3.2.2.8 F Nucleoside
HKPMIKFJ_00525 2.5e-158 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HKPMIKFJ_00526 3.7e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HKPMIKFJ_00527 1.7e-143 noc K Belongs to the ParB family
HKPMIKFJ_00528 4.1e-136 soj D Sporulation initiation inhibitor
HKPMIKFJ_00529 3.4e-155 spo0J K Belongs to the ParB family
HKPMIKFJ_00530 8.5e-33 yyzM S Bacterial protein of unknown function (DUF951)
HKPMIKFJ_00531 9.8e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKPMIKFJ_00532 1.2e-132 XK27_01040 S Protein of unknown function (DUF1129)
HKPMIKFJ_00533 9.4e-74
HKPMIKFJ_00534 1.2e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKPMIKFJ_00535 3.5e-123 K response regulator
HKPMIKFJ_00536 5.3e-212 hpk31 2.7.13.3 T Histidine kinase
HKPMIKFJ_00537 1.9e-234 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKPMIKFJ_00538 8.7e-161 V domain protein
HKPMIKFJ_00539 5.6e-37 S Domain of unknown function (DUF4430)
HKPMIKFJ_00540 6.8e-248 gor 1.8.1.7 C Glutathione reductase
HKPMIKFJ_00541 1.9e-86 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HKPMIKFJ_00542 7.2e-136 azlC E AzlC protein
HKPMIKFJ_00543 1.3e-52 azlD S branched-chain amino acid
HKPMIKFJ_00544 1.2e-235 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HKPMIKFJ_00545 2.2e-120
HKPMIKFJ_00546 1.3e-210 xylR GK ROK family
HKPMIKFJ_00547 6.8e-169 K AI-2E family transporter
HKPMIKFJ_00548 1.6e-256 M domain protein
HKPMIKFJ_00549 1.2e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKPMIKFJ_00550 1.5e-83 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
HKPMIKFJ_00551 1.7e-38
HKPMIKFJ_00552 5.8e-34 S Protein of unknown function (DUF3781)
HKPMIKFJ_00554 2.2e-16 K helix_turn_helix, mercury resistance
HKPMIKFJ_00555 7.5e-68 yobT S PFAM Metallo-beta-lactamase superfamily
HKPMIKFJ_00556 5.1e-222 EGP Major facilitator Superfamily
HKPMIKFJ_00557 1.9e-159 3.1.3.48 T Tyrosine phosphatase family
HKPMIKFJ_00558 8.9e-191 yjcE P Sodium proton antiporter
HKPMIKFJ_00559 1.9e-23 thiJ-2 3.5.1.124 S DJ-1/PfpI family
HKPMIKFJ_00560 4.2e-68 thiJ-2 3.5.1.124 S DJ-1/PfpI family
HKPMIKFJ_00561 4.6e-208 ykiI
HKPMIKFJ_00563 3.2e-261 ytjP 3.5.1.18 E Dipeptidase
HKPMIKFJ_00564 1.2e-280 arcD S C4-dicarboxylate anaerobic carrier
HKPMIKFJ_00565 6.5e-148 KT YcbB domain
HKPMIKFJ_00566 5.3e-221 2.1.1.80, 2.7.13.3, 3.1.1.61 T histidine kinase DNA gyrase B
HKPMIKFJ_00567 5.7e-278 S C4-dicarboxylate anaerobic carrier
HKPMIKFJ_00568 7.7e-238 arcA 3.5.3.6 E Arginine
HKPMIKFJ_00569 1.2e-196 argF 2.1.3.3, 2.1.3.6, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKPMIKFJ_00570 8.5e-257 arcD E Arginine ornithine antiporter
HKPMIKFJ_00571 6.8e-217 arcT 2.6.1.1 E Aminotransferase
HKPMIKFJ_00572 1.8e-170 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HKPMIKFJ_00573 6.2e-120 iprA K Cyclic nucleotide-monophosphate binding domain
HKPMIKFJ_00574 3.1e-130 XK27_07210 6.1.1.6 S B3 4 domain
HKPMIKFJ_00575 1.6e-30 U Protein of unknown function DUF262
HKPMIKFJ_00576 3e-59 L Transposase
HKPMIKFJ_00577 1.1e-198 L Transposase
HKPMIKFJ_00578 7.3e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKPMIKFJ_00579 3.1e-192 htrA 3.4.21.107 O serine protease
HKPMIKFJ_00580 3.4e-157 vicX 3.1.26.11 S domain protein
HKPMIKFJ_00581 1.9e-150 yycI S YycH protein
HKPMIKFJ_00582 3.7e-238 yycH S YycH protein
HKPMIKFJ_00583 0.0 vicK 2.7.13.3 T Histidine kinase
HKPMIKFJ_00584 5.7e-132 K response regulator
HKPMIKFJ_00586 1.7e-129 E Matrixin
HKPMIKFJ_00587 1.3e-38
HKPMIKFJ_00588 9e-303 E ABC transporter, substratebinding protein
HKPMIKFJ_00589 1.8e-22
HKPMIKFJ_00590 3.5e-211 yttB EGP Major facilitator Superfamily
HKPMIKFJ_00591 4.2e-100 S NADPH-dependent FMN reductase
HKPMIKFJ_00592 6e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HKPMIKFJ_00594 2.1e-63 rplI J Binds to the 23S rRNA
HKPMIKFJ_00595 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HKPMIKFJ_00596 5.5e-66 S membrane transporter protein
HKPMIKFJ_00597 1e-99 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_00598 4.9e-301 E ABC transporter, substratebinding protein
HKPMIKFJ_00599 1.2e-227 Q Imidazolonepropionase and related amidohydrolases
HKPMIKFJ_00600 7.5e-115
HKPMIKFJ_00601 1.7e-301 E ABC transporter, substratebinding protein
HKPMIKFJ_00602 3.1e-228 Q Imidazolonepropionase and related amidohydrolases
HKPMIKFJ_00603 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKPMIKFJ_00604 3e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKPMIKFJ_00605 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HKPMIKFJ_00606 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKPMIKFJ_00607 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKPMIKFJ_00608 1.7e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKPMIKFJ_00609 2e-35 yaaA S S4 domain protein YaaA
HKPMIKFJ_00610 4.7e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKPMIKFJ_00611 1.7e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKPMIKFJ_00612 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HKPMIKFJ_00613 3.2e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKPMIKFJ_00614 2.3e-145 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKPMIKFJ_00615 2.9e-110 jag S R3H domain protein
HKPMIKFJ_00616 3.2e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKPMIKFJ_00617 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKPMIKFJ_00618 5.7e-54
HKPMIKFJ_00619 3e-37
HKPMIKFJ_00620 2.6e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HKPMIKFJ_00621 3.7e-36
HKPMIKFJ_00622 5.5e-245 brnQ U Component of the transport system for branched-chain amino acids
HKPMIKFJ_00623 4.8e-114 ywnB S NAD(P)H-binding
HKPMIKFJ_00624 1.4e-98 J Acetyltransferase (GNAT) domain
HKPMIKFJ_00625 1.2e-91 ykhA 3.1.2.20 I Thioesterase superfamily
HKPMIKFJ_00626 1.6e-224 S module of peptide synthetase
HKPMIKFJ_00627 9.8e-206 tcaB EGP Major facilitator Superfamily
HKPMIKFJ_00628 4.2e-109 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HKPMIKFJ_00629 2.6e-77 K helix_turn_helix multiple antibiotic resistance protein
HKPMIKFJ_00630 1.6e-252 pepC 3.4.22.40 E aminopeptidase
HKPMIKFJ_00631 1.1e-110 L haloacid dehalogenase-like hydrolase
HKPMIKFJ_00632 8e-51
HKPMIKFJ_00634 3.3e-233 aguA 3.2.1.139 G Glycosyl hydrolase 67
HKPMIKFJ_00635 1.5e-67
HKPMIKFJ_00636 1.2e-32 ykzG S Belongs to the UPF0356 family
HKPMIKFJ_00637 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKPMIKFJ_00638 4.8e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HKPMIKFJ_00639 1.3e-28
HKPMIKFJ_00640 1.1e-116 mltD CBM50 M NlpC P60 family protein
HKPMIKFJ_00641 9.7e-165 ypuA S Protein of unknown function (DUF1002)
HKPMIKFJ_00642 4.2e-169 ykfC 3.4.14.13 M NlpC/P60 family
HKPMIKFJ_00643 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKPMIKFJ_00644 2.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKPMIKFJ_00645 4e-184 rbsR K helix_turn _helix lactose operon repressor
HKPMIKFJ_00646 3.1e-189 yghZ C Aldo keto reductase family protein
HKPMIKFJ_00647 8.4e-157 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKPMIKFJ_00648 8e-307 E ABC transporter, substratebinding protein
HKPMIKFJ_00649 4.1e-278 nylA 3.5.1.4 J Belongs to the amidase family
HKPMIKFJ_00650 1.9e-158 yckB ET Belongs to the bacterial solute-binding protein 3 family
HKPMIKFJ_00651 2.5e-121 yecS E ABC transporter permease
HKPMIKFJ_00652 5.9e-126 yoaK S Protein of unknown function (DUF1275)
HKPMIKFJ_00653 1.4e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKPMIKFJ_00654 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKPMIKFJ_00655 6.8e-119 S Repeat protein
HKPMIKFJ_00656 3.5e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HKPMIKFJ_00657 8.4e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKPMIKFJ_00659 1.5e-58 XK27_04120 S Putative amino acid metabolism
HKPMIKFJ_00660 5.8e-222 iscS 2.8.1.7 E Aminotransferase class V
HKPMIKFJ_00661 2.7e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKPMIKFJ_00662 3.2e-28
HKPMIKFJ_00663 2.5e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HKPMIKFJ_00664 2.2e-34 cspA K Cold shock protein
HKPMIKFJ_00665 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKPMIKFJ_00666 3.3e-92 divIVA D DivIVA domain protein
HKPMIKFJ_00667 5.4e-144 ylmH S S4 domain protein
HKPMIKFJ_00668 3.8e-39 yggT S YGGT family
HKPMIKFJ_00669 1.7e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKPMIKFJ_00670 1.1e-215 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKPMIKFJ_00671 2e-244 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKPMIKFJ_00672 1.4e-145 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKPMIKFJ_00673 3.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKPMIKFJ_00674 4.9e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKPMIKFJ_00675 1.9e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKPMIKFJ_00676 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HKPMIKFJ_00677 1.7e-61 ftsL D Cell division protein FtsL
HKPMIKFJ_00678 1.4e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKPMIKFJ_00679 2e-79 mraZ K Belongs to the MraZ family
HKPMIKFJ_00680 7.5e-61 S Protein of unknown function (DUF3397)
HKPMIKFJ_00681 2.2e-12 S Protein of unknown function (DUF4044)
HKPMIKFJ_00682 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HKPMIKFJ_00683 2.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKPMIKFJ_00684 2.2e-159 rrmA 2.1.1.187 H Methyltransferase
HKPMIKFJ_00685 1.6e-203 XK27_05220 S AI-2E family transporter
HKPMIKFJ_00686 6.2e-106 cutC P Participates in the control of copper homeostasis
HKPMIKFJ_00688 3.9e-58 N Cell shape-determining protein MreB
HKPMIKFJ_00689 2.9e-69 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKPMIKFJ_00690 0.0
HKPMIKFJ_00691 1.3e-37
HKPMIKFJ_00692 3.6e-271 pipD E Peptidase family C69
HKPMIKFJ_00693 1.1e-119 ntcA2 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HKPMIKFJ_00694 0.0 asnB 6.3.5.4 E Asparagine synthase
HKPMIKFJ_00695 9.6e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
HKPMIKFJ_00696 1.6e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HKPMIKFJ_00697 2.8e-52 S Protein of unknown function (DUF1516)
HKPMIKFJ_00698 2.4e-95 1.5.1.3 H RibD C-terminal domain
HKPMIKFJ_00699 5.5e-231 3.2.1.96, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HKPMIKFJ_00700 1.1e-17
HKPMIKFJ_00702 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HKPMIKFJ_00703 4.7e-79 argR K Regulates arginine biosynthesis genes
HKPMIKFJ_00704 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKPMIKFJ_00705 1.4e-51 yheA S Belongs to the UPF0342 family
HKPMIKFJ_00706 4.2e-228 yhaO L Ser Thr phosphatase family protein
HKPMIKFJ_00707 0.0 L AAA domain
HKPMIKFJ_00708 3.9e-184 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKPMIKFJ_00709 9.1e-151 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKPMIKFJ_00710 2.8e-46
HKPMIKFJ_00711 3.1e-83 hit FG histidine triad
HKPMIKFJ_00712 5.7e-134 ecsA V ABC transporter, ATP-binding protein
HKPMIKFJ_00713 5.7e-217 ecsB U ABC transporter
HKPMIKFJ_00714 4.3e-149 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HKPMIKFJ_00715 2.5e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKPMIKFJ_00716 1.6e-186 coiA 3.6.4.12 S Competence protein
HKPMIKFJ_00717 0.0 pepF E oligoendopeptidase F
HKPMIKFJ_00718 2.5e-158 degV S DegV family
HKPMIKFJ_00719 9.9e-112 yjbH Q Thioredoxin
HKPMIKFJ_00720 3.3e-118 yjbM 2.7.6.5 S RelA SpoT domain protein
HKPMIKFJ_00721 6.8e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKPMIKFJ_00722 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HKPMIKFJ_00723 8e-34 N Cell shape-determining protein MreB
HKPMIKFJ_00724 3.2e-153 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HKPMIKFJ_00725 2.3e-159 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HKPMIKFJ_00727 5.4e-164 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HKPMIKFJ_00729 9.5e-30 vat S acetyltransferase, isoleucine patch superfamily
HKPMIKFJ_00730 2e-72 vat S acetyltransferase, isoleucine patch superfamily
HKPMIKFJ_00731 3.2e-153 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HKPMIKFJ_00732 4e-188 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HKPMIKFJ_00733 1e-242 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HKPMIKFJ_00734 2.1e-68 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKPMIKFJ_00735 1.3e-114 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKPMIKFJ_00736 0.0 yhcA V ABC transporter, ATP-binding protein
HKPMIKFJ_00737 7.2e-101 bm3R1 K Psort location Cytoplasmic, score
HKPMIKFJ_00738 6.7e-66 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKPMIKFJ_00739 6.4e-38 S Mor transcription activator family
HKPMIKFJ_00740 1.1e-40 S Mor transcription activator family
HKPMIKFJ_00741 2.1e-19 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HKPMIKFJ_00742 4e-19 S Mor transcription activator family
HKPMIKFJ_00743 3.7e-123 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HKPMIKFJ_00744 7.5e-190 ybhR V ABC transporter
HKPMIKFJ_00745 1.3e-111 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_00746 6.8e-177 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKPMIKFJ_00747 8.6e-57 yqkB S Belongs to the HesB IscA family
HKPMIKFJ_00748 1.9e-193 yjcE P Sodium proton antiporter
HKPMIKFJ_00749 3e-23 yeaN P Major Facilitator Superfamily
HKPMIKFJ_00750 0.0 kup P Transport of potassium into the cell
HKPMIKFJ_00751 1.3e-49 S Alpha/beta hydrolase family
HKPMIKFJ_00752 9.2e-178 C Zinc-binding dehydrogenase
HKPMIKFJ_00753 1.8e-99 1.1.1.219 GM Male sterility protein
HKPMIKFJ_00754 1.4e-72 K helix_turn_helix, mercury resistance
HKPMIKFJ_00755 3.8e-32 P ATPases associated with a variety of cellular activities
HKPMIKFJ_00757 2.5e-197 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HKPMIKFJ_00758 1.3e-77 K Transcriptional regulator
HKPMIKFJ_00759 3.8e-162 akr5f 1.1.1.346 S reductase
HKPMIKFJ_00760 1e-164 S Oxidoreductase, aldo keto reductase family protein
HKPMIKFJ_00761 4.7e-79
HKPMIKFJ_00762 1.9e-214 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HKPMIKFJ_00763 3e-153 yitU 3.1.3.104 S hydrolase
HKPMIKFJ_00764 1.1e-266 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HKPMIKFJ_00765 2.3e-190 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKPMIKFJ_00766 6.4e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HKPMIKFJ_00767 4.2e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HKPMIKFJ_00768 1e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HKPMIKFJ_00769 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HKPMIKFJ_00770 2.6e-83 ypmB S Protein conserved in bacteria
HKPMIKFJ_00771 6.8e-207 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HKPMIKFJ_00772 1e-122 dnaD L Replication initiation and membrane attachment
HKPMIKFJ_00773 3.9e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HKPMIKFJ_00774 8.5e-60 P Rhodanese Homology Domain
HKPMIKFJ_00775 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HKPMIKFJ_00776 1e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKPMIKFJ_00777 8e-105 ypsA S Belongs to the UPF0398 family
HKPMIKFJ_00778 6.4e-28 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKPMIKFJ_00780 6.1e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HKPMIKFJ_00781 5.8e-67 FG Scavenger mRNA decapping enzyme C-term binding
HKPMIKFJ_00782 3.2e-245 amtB P ammonium transporter
HKPMIKFJ_00783 4.8e-28
HKPMIKFJ_00784 9.7e-84 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
HKPMIKFJ_00785 2e-53
HKPMIKFJ_00786 4.5e-123 S CAAX protease self-immunity
HKPMIKFJ_00787 7.2e-84 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_00788 1.9e-32 U Protein of unknown function DUF262
HKPMIKFJ_00789 2e-82
HKPMIKFJ_00791 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKPMIKFJ_00792 1.3e-74 K Acetyltransferase (GNAT) domain
HKPMIKFJ_00793 2.8e-165
HKPMIKFJ_00794 4e-106 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKPMIKFJ_00795 1e-11 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HKPMIKFJ_00797 2.2e-142 ydhO 3.4.14.13 M NlpC/P60 family
HKPMIKFJ_00798 1.7e-103 S regulation of response to stimulus
HKPMIKFJ_00799 9.7e-118 lsa S ABC transporter
HKPMIKFJ_00800 8.7e-81 argO S LysE type translocator
HKPMIKFJ_00801 7.8e-36 mgrA K helix_turn_helix multiple antibiotic resistance protein
HKPMIKFJ_00802 1.8e-141 nlhH I Esterase
HKPMIKFJ_00803 1.1e-175 draG 3.2.2.24 O ADP-ribosylglycohydrolase
HKPMIKFJ_00804 4.2e-96 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HKPMIKFJ_00806 2.4e-88 cadD P Cadmium resistance transporter
HKPMIKFJ_00807 9.1e-77 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
HKPMIKFJ_00808 2.4e-76 gtrA S GtrA-like protein
HKPMIKFJ_00809 4.5e-302 E Bacterial extracellular solute-binding proteins, family 5 Middle
HKPMIKFJ_00810 7.3e-115 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_00811 3.7e-227 XK27_06930 S ABC-2 family transporter protein
HKPMIKFJ_00812 5.1e-132 qmcA O prohibitin homologues
HKPMIKFJ_00813 5.7e-55 S protein encoded in hypervariable junctions of pilus gene clusters
HKPMIKFJ_00814 3.6e-22
HKPMIKFJ_00815 1.7e-99 GBS0088 S Nucleotidyltransferase
HKPMIKFJ_00816 3.7e-85 yybC S Protein of unknown function (DUF2798)
HKPMIKFJ_00817 3.4e-56 ydiI Q Thioesterase superfamily
HKPMIKFJ_00818 7.1e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HKPMIKFJ_00819 8.6e-265 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HKPMIKFJ_00820 1.3e-93 S Protein of unknown function (DUF1097)
HKPMIKFJ_00821 7.2e-167
HKPMIKFJ_00822 1.4e-286 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKPMIKFJ_00823 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HKPMIKFJ_00824 2.2e-210 lmrP E Major Facilitator Superfamily
HKPMIKFJ_00827 1.5e-106 dhaS K Bacterial regulatory proteins, tetR family
HKPMIKFJ_00828 5.8e-280 E amino acid
HKPMIKFJ_00829 5.5e-280 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HKPMIKFJ_00830 8.4e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKPMIKFJ_00831 5.5e-172
HKPMIKFJ_00832 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKPMIKFJ_00833 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKPMIKFJ_00834 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKPMIKFJ_00835 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKPMIKFJ_00836 3.8e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKPMIKFJ_00837 4.2e-71 yabR J RNA binding
HKPMIKFJ_00838 9.7e-44 divIC D Septum formation initiator
HKPMIKFJ_00839 1.6e-39 yabO J S4 domain protein
HKPMIKFJ_00840 9.1e-292 yabM S Polysaccharide biosynthesis protein
HKPMIKFJ_00841 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKPMIKFJ_00842 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKPMIKFJ_00843 2.2e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKPMIKFJ_00844 4.8e-252 S Putative peptidoglycan binding domain
HKPMIKFJ_00846 1.1e-113 S (CBS) domain
HKPMIKFJ_00847 8.1e-61 ndoA L Toxic component of a toxin-antitoxin (TA) module
HKPMIKFJ_00849 8.1e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKPMIKFJ_00850 2.9e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKPMIKFJ_00851 2.4e-209 S nuclear-transcribed mRNA catabolic process, no-go decay
HKPMIKFJ_00852 2.1e-240 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKPMIKFJ_00853 1e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKPMIKFJ_00854 1.9e-149
HKPMIKFJ_00855 6.8e-143 htpX O Belongs to the peptidase M48B family
HKPMIKFJ_00856 9.9e-95 lemA S LemA family
HKPMIKFJ_00857 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKPMIKFJ_00858 1.3e-251 XK27_00720 S Leucine-rich repeat (LRR) protein
HKPMIKFJ_00859 1.8e-109 XK27_00720 S regulation of response to stimulus
HKPMIKFJ_00860 4e-110 S Cell surface protein
HKPMIKFJ_00861 3.2e-28 S WxL domain surface cell wall-binding
HKPMIKFJ_00862 5.1e-13 S WxL domain surface cell wall-binding
HKPMIKFJ_00864 9.9e-80 XK27_00720 S regulation of response to stimulus
HKPMIKFJ_00865 7.1e-11 S WxL domain surface cell wall-binding
HKPMIKFJ_00866 3.6e-302 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HKPMIKFJ_00867 9.2e-116 yoaK S Protein of unknown function (DUF1275)
HKPMIKFJ_00868 3.9e-157 rihA F Inosine-uridine preferring nucleoside hydrolase
HKPMIKFJ_00870 1.2e-177 K helix_turn _helix lactose operon repressor
HKPMIKFJ_00871 6.1e-29 mcbG S Pentapeptide repeats (8 copies)
HKPMIKFJ_00872 1e-99 ywlG S Belongs to the UPF0340 family
HKPMIKFJ_00873 6.8e-84 hmpT S ECF-type riboflavin transporter, S component
HKPMIKFJ_00874 2.6e-138 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H Phosphomethylpyrimidine kinase
HKPMIKFJ_00875 2e-258 norG_2 K Aminotransferase class I and II
HKPMIKFJ_00876 6.8e-71 4.4.1.5 E Glyoxalase
HKPMIKFJ_00877 3.6e-140 S Membrane
HKPMIKFJ_00878 2.8e-185 tdh 1.1.1.14 C Zinc-binding dehydrogenase
HKPMIKFJ_00879 6.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HKPMIKFJ_00880 6.4e-75
HKPMIKFJ_00881 9.5e-50 ykkC P Small Multidrug Resistance protein
HKPMIKFJ_00882 2.2e-51 sugE P Multidrug resistance protein
HKPMIKFJ_00883 1.6e-99 speG J Acetyltransferase (GNAT) domain
HKPMIKFJ_00884 3.6e-146 G Belongs to the phosphoglycerate mutase family
HKPMIKFJ_00885 1.1e-18 S integral membrane protein
HKPMIKFJ_00886 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
HKPMIKFJ_00887 9e-195 nlhH_1 I alpha/beta hydrolase fold
HKPMIKFJ_00888 5.8e-250 xylP2 G symporter
HKPMIKFJ_00889 8.3e-45 S CRISPR-associated protein (Cas_Csn2)
HKPMIKFJ_00890 4.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKPMIKFJ_00891 9.1e-95 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKPMIKFJ_00892 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKPMIKFJ_00893 3.8e-301 E ABC transporter, substratebinding protein
HKPMIKFJ_00894 4.9e-82
HKPMIKFJ_00895 1.2e-08
HKPMIKFJ_00896 5.2e-176 K Transcriptional regulator, LacI family
HKPMIKFJ_00897 1.1e-261 G Major Facilitator
HKPMIKFJ_00898 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HKPMIKFJ_00899 1.5e-115
HKPMIKFJ_00900 6.4e-75 K helix_turn_helix, mercury resistance
HKPMIKFJ_00901 1.6e-196 tra L COG2826 Transposase and inactivated derivatives, IS30 family
HKPMIKFJ_00902 1.8e-136 S NAD:arginine ADP-ribosyltransferase
HKPMIKFJ_00905 4.4e-80 tspO T TspO/MBR family
HKPMIKFJ_00906 0.0 S Bacterial membrane protein YfhO
HKPMIKFJ_00907 7.1e-261 pgi 5.3.1.9 G Belongs to the GPI family
HKPMIKFJ_00908 2.9e-154 glcU U sugar transport
HKPMIKFJ_00909 1.1e-209 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
HKPMIKFJ_00910 1.9e-267 T PhoQ Sensor
HKPMIKFJ_00911 9e-147 K response regulator
HKPMIKFJ_00914 3.5e-16
HKPMIKFJ_00915 4.7e-106
HKPMIKFJ_00916 0.0 rafA 3.2.1.22 G Melibiase
HKPMIKFJ_00917 2.5e-119 K AraC family transcriptional regulator
HKPMIKFJ_00918 3.7e-210 G MFS/sugar transport protein
HKPMIKFJ_00919 1.2e-252 dapE 3.5.1.18 E Peptidase dimerisation domain
HKPMIKFJ_00920 4.8e-203 E Bacterial extracellular solute-binding proteins, family 5 Middle
HKPMIKFJ_00921 3.8e-72 S Sigma factor regulator C-terminal
HKPMIKFJ_00922 9.3e-46 sigM K Sigma-70 region 2
HKPMIKFJ_00923 8.1e-252 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKPMIKFJ_00924 1.5e-86
HKPMIKFJ_00925 2e-56 ypaA S Protein of unknown function (DUF1304)
HKPMIKFJ_00927 3.2e-23
HKPMIKFJ_00928 6e-79 O OsmC-like protein
HKPMIKFJ_00929 1.9e-25
HKPMIKFJ_00930 3.3e-74 K Transcriptional regulator
HKPMIKFJ_00931 7.9e-76 S Domain of unknown function (DUF5067)
HKPMIKFJ_00932 1.6e-151 licD M LicD family
HKPMIKFJ_00933 8.3e-290 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKPMIKFJ_00934 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKPMIKFJ_00935 8.9e-170 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKPMIKFJ_00936 2.3e-139 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
HKPMIKFJ_00937 5.4e-170 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKPMIKFJ_00938 1.4e-159 isdE P Periplasmic binding protein
HKPMIKFJ_00939 6.6e-86 M Iron Transport-associated domain
HKPMIKFJ_00940 2.1e-176 M Iron Transport-associated domain
HKPMIKFJ_00941 1.1e-82 S Iron Transport-associated domain
HKPMIKFJ_00942 1.8e-50
HKPMIKFJ_00943 2.8e-199 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKPMIKFJ_00944 1.5e-25 copZ P Heavy-metal-associated domain
HKPMIKFJ_00945 1.2e-92 dps P Belongs to the Dps family
HKPMIKFJ_00946 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HKPMIKFJ_00947 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HKPMIKFJ_00948 1.6e-250 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKPMIKFJ_00949 5.9e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKPMIKFJ_00950 1.7e-12
HKPMIKFJ_00951 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKPMIKFJ_00952 7.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKPMIKFJ_00953 4.3e-135 ybbR S YbbR-like protein
HKPMIKFJ_00954 4.5e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKPMIKFJ_00955 1.2e-123 S Protein of unknown function (DUF1361)
HKPMIKFJ_00956 0.0 yjcE P Sodium proton antiporter
HKPMIKFJ_00957 5e-165 murB 1.3.1.98 M Cell wall formation
HKPMIKFJ_00958 8.4e-150 xth 3.1.11.2 L exodeoxyribonuclease III
HKPMIKFJ_00959 2.5e-100 dnaQ 2.7.7.7 L DNA polymerase III
HKPMIKFJ_00960 4.8e-193 C Aldo keto reductase family protein
HKPMIKFJ_00961 8.4e-85 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
HKPMIKFJ_00962 1.9e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HKPMIKFJ_00963 3.5e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HKPMIKFJ_00964 3e-141 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKPMIKFJ_00965 4.9e-102 yxjI
HKPMIKFJ_00966 1.3e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKPMIKFJ_00967 2.3e-81 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKPMIKFJ_00968 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKPMIKFJ_00969 2.5e-138 est 3.1.1.1 S Serine aminopeptidase, S33
HKPMIKFJ_00970 4.9e-32 secG U Preprotein translocase
HKPMIKFJ_00971 6.5e-282 clcA P chloride
HKPMIKFJ_00973 8e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKPMIKFJ_00974 2.1e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKPMIKFJ_00975 4.3e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HKPMIKFJ_00976 9e-192 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKPMIKFJ_00977 3.1e-184 cggR K Putative sugar-binding domain
HKPMIKFJ_00979 1.4e-107 S ECF transporter, substrate-specific component
HKPMIKFJ_00981 1.3e-120 liaI S membrane
HKPMIKFJ_00982 1.3e-70 XK27_02470 K LytTr DNA-binding domain
HKPMIKFJ_00983 2.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKPMIKFJ_00984 9.9e-169 whiA K May be required for sporulation
HKPMIKFJ_00985 4.5e-191 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HKPMIKFJ_00986 4.8e-165 rapZ S Displays ATPase and GTPase activities
HKPMIKFJ_00987 2.4e-90 S Short repeat of unknown function (DUF308)
HKPMIKFJ_00988 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKPMIKFJ_00989 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKPMIKFJ_00990 6.5e-93 K acetyltransferase
HKPMIKFJ_00991 1.9e-115 yfbR S HD containing hydrolase-like enzyme
HKPMIKFJ_00993 4.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKPMIKFJ_00994 5.8e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKPMIKFJ_00995 3.4e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HKPMIKFJ_00996 8e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKPMIKFJ_00997 1.4e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKPMIKFJ_00998 1.2e-29 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HKPMIKFJ_00999 1.7e-54 pspC KT PspC domain protein
HKPMIKFJ_01000 6.8e-119 phoU P Plays a role in the regulation of phosphate uptake
HKPMIKFJ_01001 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKPMIKFJ_01002 9.1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKPMIKFJ_01003 1e-154 pstA P Phosphate transport system permease protein PstA
HKPMIKFJ_01004 2e-158 pstC P probably responsible for the translocation of the substrate across the membrane
HKPMIKFJ_01005 6.1e-160 pstS P Phosphate
HKPMIKFJ_01006 3.2e-245 phoR 2.7.13.3 T Histidine kinase
HKPMIKFJ_01007 2e-129 K response regulator
HKPMIKFJ_01008 3.1e-220 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HKPMIKFJ_01009 8e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKPMIKFJ_01010 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKPMIKFJ_01011 7.9e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKPMIKFJ_01012 3.4e-118 comFC S Competence protein
HKPMIKFJ_01013 7.7e-252 comFA L Helicase C-terminal domain protein
HKPMIKFJ_01014 3.5e-112 yvyE 3.4.13.9 S YigZ family
HKPMIKFJ_01015 3.6e-178 tagO 2.7.8.33, 2.7.8.35 M transferase
HKPMIKFJ_01016 6.1e-60 lrgA S LrgA family
HKPMIKFJ_01017 3.7e-140 lrgB M LrgB-like family
HKPMIKFJ_01018 0.0 ydaO E amino acid
HKPMIKFJ_01019 4.2e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKPMIKFJ_01020 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKPMIKFJ_01021 2e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKPMIKFJ_01022 0.0 uup S ABC transporter, ATP-binding protein
HKPMIKFJ_01023 7.5e-46 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKPMIKFJ_01024 1.6e-211 yeaN P Transporter, major facilitator family protein
HKPMIKFJ_01025 1.4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKPMIKFJ_01026 2.6e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HKPMIKFJ_01027 1.8e-125 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HKPMIKFJ_01028 5.8e-140 fat 3.1.2.21 I Acyl-ACP thioesterase
HKPMIKFJ_01029 1.1e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKPMIKFJ_01030 3.3e-37 yabA L Involved in initiation control of chromosome replication
HKPMIKFJ_01031 1.5e-178 holB 2.7.7.7 L DNA polymerase III
HKPMIKFJ_01032 2.2e-54 yaaQ S Cyclic-di-AMP receptor
HKPMIKFJ_01033 6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKPMIKFJ_01034 1.3e-38 yaaL S Protein of unknown function (DUF2508)
HKPMIKFJ_01035 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKPMIKFJ_01036 3.6e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKPMIKFJ_01037 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKPMIKFJ_01038 2.5e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKPMIKFJ_01039 5.8e-109 rsmC 2.1.1.172 J Methyltransferase
HKPMIKFJ_01040 6.4e-37 nrdH O Glutaredoxin
HKPMIKFJ_01041 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKPMIKFJ_01042 5.5e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKPMIKFJ_01043 5.3e-167 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HKPMIKFJ_01044 2.4e-109 yvdD 3.2.2.10 S Belongs to the LOG family
HKPMIKFJ_01045 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKPMIKFJ_01046 4e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKPMIKFJ_01047 6.9e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKPMIKFJ_01048 1.2e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKPMIKFJ_01049 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKPMIKFJ_01050 1.1e-98 nusG K Participates in transcription elongation, termination and antitermination
HKPMIKFJ_01051 3.3e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKPMIKFJ_01052 1.5e-98 sigH K Sigma-70 region 2
HKPMIKFJ_01053 3.1e-90 yacP S YacP-like NYN domain
HKPMIKFJ_01054 2.5e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKPMIKFJ_01055 7.8e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKPMIKFJ_01056 7.4e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKPMIKFJ_01057 1.2e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKPMIKFJ_01058 4.9e-213 yacL S domain protein
HKPMIKFJ_01059 4.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKPMIKFJ_01060 2.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HKPMIKFJ_01061 2e-55
HKPMIKFJ_01062 5.3e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKPMIKFJ_01064 4.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
HKPMIKFJ_01065 2.3e-229 V Beta-lactamase
HKPMIKFJ_01066 7.7e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKPMIKFJ_01067 4.7e-172 EG EamA-like transporter family
HKPMIKFJ_01068 7.9e-166 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HKPMIKFJ_01069 1.5e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HKPMIKFJ_01070 2.2e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
HKPMIKFJ_01071 3e-197 XK27_06930 V domain protein
HKPMIKFJ_01072 2.8e-102 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_01073 5.5e-118 yliE T EAL domain
HKPMIKFJ_01074 5.3e-16 2.7.7.65 T diguanylate cyclase
HKPMIKFJ_01075 1.3e-159 2.7.7.65 T diguanylate cyclase
HKPMIKFJ_01076 2.9e-177 K AI-2E family transporter
HKPMIKFJ_01077 2.5e-155 manN G system, mannose fructose sorbose family IID component
HKPMIKFJ_01078 1.1e-117 manM G PTS system
HKPMIKFJ_01079 1.4e-60 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
HKPMIKFJ_01080 1.6e-54 manL 2.7.1.191 G PTS system fructose IIA component
HKPMIKFJ_01081 8.3e-108 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HKPMIKFJ_01082 3e-246 dinF V MatE
HKPMIKFJ_01083 7.3e-74 K MarR family
HKPMIKFJ_01084 2.6e-98 S Psort location CytoplasmicMembrane, score
HKPMIKFJ_01085 3e-115 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HKPMIKFJ_01086 2.4e-61 yobS K transcriptional regulator
HKPMIKFJ_01087 1.1e-123 S Alpha/beta hydrolase family
HKPMIKFJ_01088 1.9e-151 4.1.1.52 S Amidohydrolase
HKPMIKFJ_01090 3.7e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKPMIKFJ_01091 4e-89 ydcK S Belongs to the SprT family
HKPMIKFJ_01092 0.0 yhgF K Tex-like protein N-terminal domain protein
HKPMIKFJ_01093 1.4e-72
HKPMIKFJ_01094 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKPMIKFJ_01095 4.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKPMIKFJ_01096 4.5e-140 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKPMIKFJ_01097 6.9e-92 MA20_25245 K FR47-like protein
HKPMIKFJ_01098 1.9e-124 gntR1 K UbiC transcription regulator-associated domain protein
HKPMIKFJ_01099 2.4e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKPMIKFJ_01100 2.6e-133 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKPMIKFJ_01103 2e-64 yjjH S Calcineurin-like phosphoesterase
HKPMIKFJ_01104 5.5e-74 yjjH S Calcineurin-like phosphoesterase
HKPMIKFJ_01105 1.1e-297 dtpT U amino acid peptide transporter
HKPMIKFJ_01106 9.9e-52 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HKPMIKFJ_01109 6.1e-16 K toxin-antitoxin pair type II binding
HKPMIKFJ_01110 6.4e-23
HKPMIKFJ_01112 5e-93 K helix_turn_helix multiple antibiotic resistance protein
HKPMIKFJ_01113 2.1e-158 drrA V ABC transporter
HKPMIKFJ_01114 8.1e-116 drrB U ABC-2 type transporter
HKPMIKFJ_01115 2.1e-99 K LysR substrate binding domain
HKPMIKFJ_01116 1.3e-91 S Protein of unknown function (DUF554)
HKPMIKFJ_01117 2.8e-168 2.5.1.74 H UbiA prenyltransferase family
HKPMIKFJ_01118 0.0 S Bacterial membrane protein YfhO
HKPMIKFJ_01119 1.2e-86 ccl S QueT transporter
HKPMIKFJ_01121 2.9e-32 3.2.1.17 M hydrolase, family 25
HKPMIKFJ_01122 9.1e-29 S Bacterial SH3 domain
HKPMIKFJ_01123 5.1e-30
HKPMIKFJ_01124 1.1e-130 S Bacterial SH3 domain
HKPMIKFJ_01125 6.3e-29 M hydrolase, family 25
HKPMIKFJ_01126 0.0 S Predicted membrane protein (DUF2207)
HKPMIKFJ_01127 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HKPMIKFJ_01128 5.2e-281 xynT G MFS/sugar transport protein
HKPMIKFJ_01129 1.5e-150 rhaS2 K Transcriptional regulator, AraC family
HKPMIKFJ_01130 3.7e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKPMIKFJ_01131 7.5e-21
HKPMIKFJ_01132 1.1e-147 F DNA/RNA non-specific endonuclease
HKPMIKFJ_01133 4.5e-89
HKPMIKFJ_01136 4.2e-171 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HKPMIKFJ_01137 2.1e-152 xynB 3.2.1.37 GH43 K family 39
HKPMIKFJ_01138 6.7e-116 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
HKPMIKFJ_01139 1.6e-115 G MFS/sugar transport protein
HKPMIKFJ_01140 1.3e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HKPMIKFJ_01141 8.9e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKPMIKFJ_01142 4.6e-76 3.6.1.55 F NUDIX domain
HKPMIKFJ_01143 3.6e-199 xerS L Belongs to the 'phage' integrase family
HKPMIKFJ_01144 1.3e-64 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_01145 3.8e-17 S membrane
HKPMIKFJ_01146 5.6e-89 K Transcriptional regulator
HKPMIKFJ_01147 4.9e-51 yneE K Transcriptional regulator
HKPMIKFJ_01148 1e-14 yneE K Transcriptional regulator
HKPMIKFJ_01149 5.6e-120 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKPMIKFJ_01150 3.1e-122 Q Methyltransferase domain
HKPMIKFJ_01151 1.2e-125 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HKPMIKFJ_01152 2.6e-17
HKPMIKFJ_01154 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKPMIKFJ_01155 5.9e-91 V VanZ like family
HKPMIKFJ_01156 4.5e-83 ysaA V VanZ like family
HKPMIKFJ_01157 8.7e-75 gtcA S Teichoic acid glycosylation protein
HKPMIKFJ_01158 9.2e-87 folT S ECF transporter, substrate-specific component
HKPMIKFJ_01159 7.8e-160 degV S EDD domain protein, DegV family
HKPMIKFJ_01160 6.4e-232 yxiO S Vacuole effluxer Atg22 like
HKPMIKFJ_01161 2.1e-193 npp S type I phosphodiesterase nucleotide pyrophosphatase
HKPMIKFJ_01162 6.3e-70 K Transcriptional regulator
HKPMIKFJ_01163 0.0 FbpA K Fibronectin-binding protein
HKPMIKFJ_01164 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HKPMIKFJ_01165 1.5e-205 carA 6.3.5.5 F Belongs to the CarA family
HKPMIKFJ_01166 6.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKPMIKFJ_01167 5.5e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKPMIKFJ_01168 5.7e-81 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKPMIKFJ_01169 2.8e-307 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HKPMIKFJ_01170 2.4e-56 esbA S Family of unknown function (DUF5322)
HKPMIKFJ_01171 6.8e-66 rnhA 3.1.26.4 L Ribonuclease HI
HKPMIKFJ_01172 1.4e-206 yurR 1.4.5.1 E FAD dependent oxidoreductase
HKPMIKFJ_01173 6.1e-111 XK27_02070 S Nitroreductase family
HKPMIKFJ_01174 1.7e-27 entB 3.5.1.19 Q Isochorismatase family
HKPMIKFJ_01175 3.1e-75 S Protein of unknown function (DUF3021)
HKPMIKFJ_01176 4.1e-72 K LytTr DNA-binding domain
HKPMIKFJ_01177 7.9e-46 N PFAM Uncharacterised protein family UPF0150
HKPMIKFJ_01178 3.6e-92 ydeA 3.5.1.124 S DJ-1/PfpI family
HKPMIKFJ_01179 1.5e-32 yyaQ S YjbR
HKPMIKFJ_01180 6.2e-207 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HKPMIKFJ_01181 2.1e-144 K LysR substrate binding domain
HKPMIKFJ_01182 2.1e-23 adhR K MerR, DNA binding
HKPMIKFJ_01183 2.3e-179 C Aldo/keto reductase family
HKPMIKFJ_01184 7.7e-293 katA 1.11.1.6 C Belongs to the catalase family
HKPMIKFJ_01185 7.4e-100 rimL J Acetyltransferase (GNAT) domain
HKPMIKFJ_01186 4.2e-66
HKPMIKFJ_01187 1.9e-66 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKPMIKFJ_01188 1.1e-35 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_01189 4.8e-135 K Helix-turn-helix
HKPMIKFJ_01190 1.4e-52 S Alpha/beta hydrolase of unknown function (DUF915)
HKPMIKFJ_01191 7.2e-278 yjeM E Amino Acid
HKPMIKFJ_01192 3.2e-272 pipD E Dipeptidase
HKPMIKFJ_01193 4.7e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKPMIKFJ_01194 5.5e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HKPMIKFJ_01195 2.2e-295 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKPMIKFJ_01196 2.2e-46 S Protein of unknown function (DUF2975)
HKPMIKFJ_01197 3.7e-28 yozG K Transcriptional regulator
HKPMIKFJ_01198 4.2e-96
HKPMIKFJ_01199 2.8e-84
HKPMIKFJ_01200 1.8e-211 ica2 GT2 M Glycosyl transferase family group 2
HKPMIKFJ_01201 1.6e-60 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HKPMIKFJ_01202 1.5e-145 yfiQ I Acyltransferase family
HKPMIKFJ_01203 1e-178 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
HKPMIKFJ_01204 1.9e-114 ssuA P NMT1-like family
HKPMIKFJ_01205 6.6e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HKPMIKFJ_01206 0.0 yjcE P Sodium proton antiporter
HKPMIKFJ_01207 1.9e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKPMIKFJ_01208 8.8e-44
HKPMIKFJ_01209 5.8e-169 panE2 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKPMIKFJ_01210 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
HKPMIKFJ_01211 7.2e-59 K Helix-turn-helix domain
HKPMIKFJ_01213 9.6e-289 ytgP S Polysaccharide biosynthesis protein
HKPMIKFJ_01214 1.9e-83 iap CBM50 M NlpC P60 family
HKPMIKFJ_01215 3.7e-179 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKPMIKFJ_01216 2.6e-112
HKPMIKFJ_01217 1.3e-102 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HKPMIKFJ_01218 3.2e-110 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HKPMIKFJ_01219 2.5e-77 K Winged helix DNA-binding domain
HKPMIKFJ_01220 1.3e-49
HKPMIKFJ_01222 4.4e-228 L Transposase
HKPMIKFJ_01223 3.8e-159 akr5f 1.1.1.346 C Aldo keto reductase
HKPMIKFJ_01224 1.2e-244 rarA L recombination factor protein RarA
HKPMIKFJ_01225 1e-277 rny S Endoribonuclease that initiates mRNA decay
HKPMIKFJ_01226 3.3e-121 yoaK S Protein of unknown function (DUF1275)
HKPMIKFJ_01227 1.9e-175 D Alpha beta
HKPMIKFJ_01228 0.0 pepF2 E Oligopeptidase F
HKPMIKFJ_01229 1.2e-73 K Transcriptional regulator
HKPMIKFJ_01230 5.6e-163
HKPMIKFJ_01231 6.4e-180 S DUF218 domain
HKPMIKFJ_01232 1.5e-253 brnQ U Component of the transport system for branched-chain amino acids
HKPMIKFJ_01233 4.4e-158 nanK 2.7.1.2 GK ROK family
HKPMIKFJ_01234 6.1e-252 frlA E Amino acid permease
HKPMIKFJ_01235 4.9e-26
HKPMIKFJ_01236 2e-27
HKPMIKFJ_01238 5.2e-168 S DNA/RNA non-specific endonuclease
HKPMIKFJ_01239 4.7e-88 K Putative DNA-binding domain
HKPMIKFJ_01240 5.6e-65
HKPMIKFJ_01241 9.9e-217 EK Aminotransferase, class I
HKPMIKFJ_01242 3.1e-167 K LysR substrate binding domain
HKPMIKFJ_01243 3.7e-11 S Protein of unknown function (DUF2922)
HKPMIKFJ_01244 5.1e-27
HKPMIKFJ_01245 3.4e-100 K DNA-templated transcription, initiation
HKPMIKFJ_01246 1.3e-207
HKPMIKFJ_01247 4.5e-59
HKPMIKFJ_01248 3.1e-53
HKPMIKFJ_01249 9.1e-197 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HKPMIKFJ_01250 1.3e-287 macB3 V ABC transporter, ATP-binding protein
HKPMIKFJ_01251 4e-108 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKPMIKFJ_01252 1.1e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKPMIKFJ_01253 2e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKPMIKFJ_01254 7.3e-147 vdlC S Enoyl-(Acyl carrier protein) reductase
HKPMIKFJ_01255 2.8e-129 ybbM S Uncharacterised protein family (UPF0014)
HKPMIKFJ_01256 2.8e-114 ybbL S ABC transporter, ATP-binding protein
HKPMIKFJ_01257 4.7e-274 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKPMIKFJ_01258 4.4e-91
HKPMIKFJ_01262 2.4e-138 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKPMIKFJ_01263 1.9e-152 map 3.4.11.18 E Methionine Aminopeptidase
HKPMIKFJ_01264 2.3e-23
HKPMIKFJ_01265 1.4e-246 EGP Major facilitator Superfamily
HKPMIKFJ_01266 4.3e-09
HKPMIKFJ_01267 1.1e-80 6.3.3.2 S ASCH
HKPMIKFJ_01268 0.0 oppD EP Psort location Cytoplasmic, score
HKPMIKFJ_01269 1.8e-173 etfA C Electron transfer flavoprotein FAD-binding domain
HKPMIKFJ_01270 9.3e-144 etfB C Electron transfer flavoprotein domain
HKPMIKFJ_01271 2.4e-206 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
HKPMIKFJ_01272 1e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HKPMIKFJ_01273 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKPMIKFJ_01274 2.6e-36
HKPMIKFJ_01275 1.9e-248 gph G Transporter
HKPMIKFJ_01276 1.1e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKPMIKFJ_01277 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKPMIKFJ_01278 3.2e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HKPMIKFJ_01279 1.3e-185 galR K Transcriptional regulator
HKPMIKFJ_01280 6.2e-150 L Transposase and inactivated derivatives, IS30 family
HKPMIKFJ_01281 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HKPMIKFJ_01282 1.7e-22 S Family of unknown function (DUF5388)
HKPMIKFJ_01283 8.1e-119 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HKPMIKFJ_01286 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
HKPMIKFJ_01287 1.1e-84
HKPMIKFJ_01288 3.4e-40
HKPMIKFJ_01289 1.4e-25
HKPMIKFJ_01290 0.0 L MobA MobL family protein
HKPMIKFJ_01291 6.6e-130 EGP Major facilitator Superfamily
HKPMIKFJ_01292 6.7e-163 yxaB GM Polysaccharide pyruvyl transferase
HKPMIKFJ_01293 7.5e-242 iolT EGP Major facilitator Superfamily
HKPMIKFJ_01294 1.8e-13 ytgB S Transglycosylase associated protein
HKPMIKFJ_01295 2.2e-18
HKPMIKFJ_01296 2e-89 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKPMIKFJ_01297 1.6e-15 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKPMIKFJ_01299 1.3e-276 pipD E Dipeptidase
HKPMIKFJ_01300 4.9e-150
HKPMIKFJ_01301 1.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HKPMIKFJ_01302 6.1e-117 S Elongation factor G-binding protein, N-terminal
HKPMIKFJ_01303 3.8e-168 EG EamA-like transporter family
HKPMIKFJ_01304 0.0 copB 3.6.3.4 P P-type ATPase
HKPMIKFJ_01305 7.2e-77 copR K Copper transport repressor CopY TcrY
HKPMIKFJ_01306 3.4e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKPMIKFJ_01307 3.8e-159 S reductase
HKPMIKFJ_01308 0.0 ctpA 3.6.3.54 P P-type ATPase
HKPMIKFJ_01309 1.3e-63 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HKPMIKFJ_01311 2.1e-154 yxkH G Polysaccharide deacetylase
HKPMIKFJ_01312 1.6e-159 xerD L Phage integrase, N-terminal SAM-like domain
HKPMIKFJ_01313 1.7e-190 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HKPMIKFJ_01314 3.6e-189 L Psort location Cytoplasmic, score
HKPMIKFJ_01315 0.0 traA L MobA MobL family protein
HKPMIKFJ_01316 7.2e-27
HKPMIKFJ_01317 3.4e-40
HKPMIKFJ_01319 1.4e-75 cinA 3.5.1.42 S Competence-damaged protein
HKPMIKFJ_01320 4.7e-60 K helix_turn_helix, arabinose operon control protein
HKPMIKFJ_01321 3.2e-39 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HKPMIKFJ_01322 3.2e-45 tnp2PF3 L Transposase DDE domain
HKPMIKFJ_01323 3.6e-243 3.2.1.23 G Beta-galactosidase trimerisation domain
HKPMIKFJ_01324 8.3e-118 G MFS/sugar transport protein
HKPMIKFJ_01325 1e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HKPMIKFJ_01326 3.1e-56 tnp2PF3 L Transposase DDE domain
HKPMIKFJ_01327 1.4e-31 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKPMIKFJ_01328 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HKPMIKFJ_01329 1.2e-23 S Family of unknown function (DUF5388)
HKPMIKFJ_01330 1.2e-148 L Transposase and inactivated derivatives, IS30 family
HKPMIKFJ_01331 1.5e-95 zmp1 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HKPMIKFJ_01332 4.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
HKPMIKFJ_01333 4.7e-182 K Transcriptional regulator
HKPMIKFJ_01334 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKPMIKFJ_01335 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKPMIKFJ_01336 3.2e-99 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKPMIKFJ_01337 6e-168 lacX 5.1.3.3 G Aldose 1-epimerase
HKPMIKFJ_01338 8.9e-262 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKPMIKFJ_01339 1.8e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKPMIKFJ_01340 1.7e-176 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HKPMIKFJ_01341 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKPMIKFJ_01342 4e-167 dprA LU DNA protecting protein DprA
HKPMIKFJ_01343 1.6e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKPMIKFJ_01344 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKPMIKFJ_01345 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKPMIKFJ_01346 7e-214 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HKPMIKFJ_01347 2.8e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HKPMIKFJ_01348 9.2e-205 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKPMIKFJ_01349 2e-269 lpdA 1.8.1.4 C Dehydrogenase
HKPMIKFJ_01350 3.9e-162 1.1.1.27 C L-malate dehydrogenase activity
HKPMIKFJ_01351 3e-44 yktA S Belongs to the UPF0223 family
HKPMIKFJ_01352 6.7e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HKPMIKFJ_01353 0.0 typA T GTP-binding protein TypA
HKPMIKFJ_01354 1.6e-208 ftsW D Belongs to the SEDS family
HKPMIKFJ_01355 4.4e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HKPMIKFJ_01356 2.5e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HKPMIKFJ_01357 1.8e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKPMIKFJ_01358 2.8e-196 ylbL T Belongs to the peptidase S16 family
HKPMIKFJ_01359 1.1e-105 comEA L Competence protein ComEA
HKPMIKFJ_01360 8.8e-89 comEB 3.5.4.12 F ComE operon protein 2
HKPMIKFJ_01361 0.0 comEC S Competence protein ComEC
HKPMIKFJ_01362 1.6e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
HKPMIKFJ_01363 2.1e-33 rpsT J Binds directly to 16S ribosomal RNA
HKPMIKFJ_01364 1.3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKPMIKFJ_01365 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKPMIKFJ_01366 2e-166 S Tetratricopeptide repeat
HKPMIKFJ_01367 1.9e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKPMIKFJ_01368 2.2e-222 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKPMIKFJ_01369 6.9e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKPMIKFJ_01370 6.6e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HKPMIKFJ_01371 3.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HKPMIKFJ_01372 1.1e-15
HKPMIKFJ_01373 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKPMIKFJ_01374 3.3e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKPMIKFJ_01375 1.8e-104
HKPMIKFJ_01376 1.9e-27
HKPMIKFJ_01377 1.7e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKPMIKFJ_01378 2.6e-54 yrvD S Pfam:DUF1049
HKPMIKFJ_01379 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HKPMIKFJ_01380 3.2e-92 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKPMIKFJ_01381 3.3e-77 T Universal stress protein family
HKPMIKFJ_01383 1.1e-73
HKPMIKFJ_01384 1.2e-160 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HKPMIKFJ_01385 1.7e-69 S MTH538 TIR-like domain (DUF1863)
HKPMIKFJ_01389 1e-81 ndk 2.7.4.6 F Belongs to the NDK family
HKPMIKFJ_01390 7.7e-25 KT PspC domain
HKPMIKFJ_01391 5.3e-124 G phosphoglycerate mutase
HKPMIKFJ_01392 4.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HKPMIKFJ_01393 1.4e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HKPMIKFJ_01394 6e-79
HKPMIKFJ_01395 9.3e-77 F nucleoside 2-deoxyribosyltransferase
HKPMIKFJ_01396 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKPMIKFJ_01397 1.8e-37 ynzC S UPF0291 protein
HKPMIKFJ_01398 1.6e-32 yneF S Uncharacterised protein family (UPF0154)
HKPMIKFJ_01399 4.4e-287 mdlA V ABC transporter
HKPMIKFJ_01400 0.0 mdlB V ABC transporter
HKPMIKFJ_01401 1.5e-120 plsC 2.3.1.51 I Acyltransferase
HKPMIKFJ_01402 1.8e-136 yabB 2.1.1.223 L Methyltransferase small domain
HKPMIKFJ_01403 6.4e-44 yazA L GIY-YIG catalytic domain protein
HKPMIKFJ_01404 1.5e-183 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKPMIKFJ_01405 7.2e-135 S Haloacid dehalogenase-like hydrolase
HKPMIKFJ_01406 3.8e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HKPMIKFJ_01407 1.9e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKPMIKFJ_01408 1.7e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HKPMIKFJ_01409 6.9e-85 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKPMIKFJ_01410 3.2e-74
HKPMIKFJ_01411 2.1e-148 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKPMIKFJ_01412 4.5e-138 cdsA 2.7.7.41 I Belongs to the CDS family
HKPMIKFJ_01413 7.8e-233 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HKPMIKFJ_01414 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKPMIKFJ_01415 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKPMIKFJ_01416 1.4e-38
HKPMIKFJ_01417 1.8e-81 rimP J Required for maturation of 30S ribosomal subunits
HKPMIKFJ_01418 2e-190 nusA K Participates in both transcription termination and antitermination
HKPMIKFJ_01419 2.3e-47 ylxR K Protein of unknown function (DUF448)
HKPMIKFJ_01420 1.4e-44 ylxQ J ribosomal protein
HKPMIKFJ_01421 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKPMIKFJ_01422 9.4e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKPMIKFJ_01423 1.1e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKPMIKFJ_01424 4.3e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HKPMIKFJ_01425 7.8e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKPMIKFJ_01426 5.2e-83 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKPMIKFJ_01427 0.0 dnaK O Heat shock 70 kDa protein
HKPMIKFJ_01428 4.9e-178 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKPMIKFJ_01429 4.1e-16 dltX S D-Ala-teichoic acid biosynthesis protein
HKPMIKFJ_01430 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKPMIKFJ_01431 3.8e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
HKPMIKFJ_01432 5.2e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKPMIKFJ_01433 3.2e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKPMIKFJ_01434 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKPMIKFJ_01435 1.6e-27
HKPMIKFJ_01436 2.3e-24
HKPMIKFJ_01438 1.8e-62
HKPMIKFJ_01439 9.1e-28 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKPMIKFJ_01440 1.2e-54
HKPMIKFJ_01441 9.7e-180 prmA J Ribosomal protein L11 methyltransferase
HKPMIKFJ_01442 9.2e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKPMIKFJ_01443 2.1e-57
HKPMIKFJ_01444 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKPMIKFJ_01445 1.1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKPMIKFJ_01446 1.3e-55 3.1.3.18 S HAD-hyrolase-like
HKPMIKFJ_01447 2.8e-20 3.1.3.18 S HAD-hyrolase-like
HKPMIKFJ_01448 1e-164 yniA G Fructosamine kinase
HKPMIKFJ_01449 1.3e-156 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HKPMIKFJ_01450 2.2e-96
HKPMIKFJ_01451 2.5e-247 hisS 6.1.1.21 J histidyl-tRNA synthetase
HKPMIKFJ_01452 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKPMIKFJ_01453 8.2e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKPMIKFJ_01454 1.9e-161 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKPMIKFJ_01455 6.5e-189 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKPMIKFJ_01456 8e-151 tagG U Transport permease protein
HKPMIKFJ_01457 3e-242 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
HKPMIKFJ_01458 7.3e-172 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKPMIKFJ_01459 4.8e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKPMIKFJ_01460 1.3e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HKPMIKFJ_01461 5.7e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKPMIKFJ_01462 3.4e-67 hxlR K Transcriptional regulator, HxlR family
HKPMIKFJ_01463 1.2e-71 yqeY S YqeY-like protein
HKPMIKFJ_01464 7e-181 phoH T phosphate starvation-inducible protein PhoH
HKPMIKFJ_01465 8.5e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKPMIKFJ_01466 3.4e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HKPMIKFJ_01467 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKPMIKFJ_01468 3.3e-149 recO L Involved in DNA repair and RecF pathway recombination
HKPMIKFJ_01469 1.5e-177 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HKPMIKFJ_01470 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HKPMIKFJ_01471 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKPMIKFJ_01472 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKPMIKFJ_01473 3.6e-88 K Transcriptional regulator
HKPMIKFJ_01474 0.0 ydgH S MMPL family
HKPMIKFJ_01475 6.6e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
HKPMIKFJ_01476 1.6e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKPMIKFJ_01477 2.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HKPMIKFJ_01478 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKPMIKFJ_01479 0.0 dnaE 2.7.7.7 L DNA polymerase
HKPMIKFJ_01480 2.9e-123 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HKPMIKFJ_01481 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HKPMIKFJ_01482 1.8e-167 cvfB S S1 domain
HKPMIKFJ_01483 4.6e-163 xerD D recombinase XerD
HKPMIKFJ_01484 3.1e-71 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKPMIKFJ_01485 2.1e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKPMIKFJ_01486 3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKPMIKFJ_01487 1.3e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKPMIKFJ_01488 2.7e-92 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKPMIKFJ_01489 1.4e-179 ypbB 5.1.3.1 S Helix-turn-helix domain
HKPMIKFJ_01490 3e-249 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HKPMIKFJ_01491 1.2e-24 M Lysin motif
HKPMIKFJ_01492 6.4e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HKPMIKFJ_01493 1.1e-210 rpsA 1.17.7.4 J Ribosomal protein S1
HKPMIKFJ_01494 2.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HKPMIKFJ_01495 1.5e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKPMIKFJ_01496 3.4e-233 S Tetratricopeptide repeat protein
HKPMIKFJ_01497 1.6e-171 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKPMIKFJ_01498 1.4e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKPMIKFJ_01499 0.0 yfmR S ABC transporter, ATP-binding protein
HKPMIKFJ_01500 1.8e-186 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKPMIKFJ_01501 1e-87 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKPMIKFJ_01502 2.8e-114 hlyIII S protein, hemolysin III
HKPMIKFJ_01503 1e-148 DegV S EDD domain protein, DegV family
HKPMIKFJ_01504 3.7e-160 ypmR E GDSL-like Lipase/Acylhydrolase
HKPMIKFJ_01505 2.7e-103 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HKPMIKFJ_01506 2.9e-34 yozE S Belongs to the UPF0346 family
HKPMIKFJ_01507 1.2e-72
HKPMIKFJ_01508 2.7e-32
HKPMIKFJ_01510 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HKPMIKFJ_01511 2.1e-207 npr 1.11.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HKPMIKFJ_01512 1.8e-231 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
HKPMIKFJ_01513 4.7e-100 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HKPMIKFJ_01514 5.2e-38
HKPMIKFJ_01515 1e-08 asnB 6.3.5.4 E Protein of unknown function (DUF3923)
HKPMIKFJ_01516 5e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKPMIKFJ_01517 9.6e-166 L Helix-turn-helix domain
HKPMIKFJ_01520 7.7e-13
HKPMIKFJ_01521 1.3e-185 L Transposase
HKPMIKFJ_01522 1.1e-130 S haloacid dehalogenase-like hydrolase
HKPMIKFJ_01523 1.7e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HKPMIKFJ_01524 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HKPMIKFJ_01525 1.7e-50 L Transposase and inactivated derivatives, IS30 family
HKPMIKFJ_01528 0.0 uvrA3 L ABC transporter
HKPMIKFJ_01530 5.1e-47
HKPMIKFJ_01531 1.3e-82 V VanZ like family
HKPMIKFJ_01532 3.6e-82 ohrR K Transcriptional regulator
HKPMIKFJ_01533 5e-122 S CAAX protease self-immunity
HKPMIKFJ_01534 2.9e-35
HKPMIKFJ_01535 1.2e-174 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKPMIKFJ_01536 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HKPMIKFJ_01537 1.6e-107 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HKPMIKFJ_01538 2.1e-38 S haloacid dehalogenase-like hydrolase
HKPMIKFJ_01539 8.3e-182 L PFAM Integrase, catalytic core
HKPMIKFJ_01542 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HKPMIKFJ_01543 9.5e-92 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HKPMIKFJ_01544 0.0 pepO 3.4.24.71 O Peptidase family M13
HKPMIKFJ_01545 1.5e-86 K helix_turn_helix multiple antibiotic resistance protein
HKPMIKFJ_01546 1.3e-130
HKPMIKFJ_01547 9.6e-83 uspA T Belongs to the universal stress protein A family
HKPMIKFJ_01549 1.4e-201 yibE S overlaps another CDS with the same product name
HKPMIKFJ_01550 1e-126 yibF S overlaps another CDS with the same product name
HKPMIKFJ_01552 5.2e-29 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HKPMIKFJ_01554 2.4e-56
HKPMIKFJ_01555 5e-175 L transposase, IS605 OrfB family
HKPMIKFJ_01556 2.5e-65 L Transposase IS200 like
HKPMIKFJ_01558 2.2e-113 soj D AAA domain
HKPMIKFJ_01559 3.9e-26
HKPMIKFJ_01561 1.7e-68 L Integrase
HKPMIKFJ_01564 3.2e-11 L Transposase and inactivated derivatives, IS30 family
HKPMIKFJ_01566 4.5e-28 L Replication protein
HKPMIKFJ_01569 8.8e-75 S haloacid dehalogenase-like hydrolase
HKPMIKFJ_01570 2.2e-119 dck 2.7.1.74 F Deoxynucleoside kinase
HKPMIKFJ_01571 1.8e-56 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HKPMIKFJ_01572 3.9e-260 bmr3 EGP Major facilitator Superfamily
HKPMIKFJ_01573 3.7e-213 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKPMIKFJ_01574 3.7e-107
HKPMIKFJ_01575 3e-46
HKPMIKFJ_01576 5.4e-93
HKPMIKFJ_01577 1.7e-51 ybjQ S Belongs to the UPF0145 family
HKPMIKFJ_01578 1.6e-83 zmp2 O Zinc-dependent metalloprotease
HKPMIKFJ_01591 2e-106 L Integrase
HKPMIKFJ_01592 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HKPMIKFJ_01593 5.4e-59 yafQ S endonuclease activity
HKPMIKFJ_01595 7.4e-87 rlmI 2.1.1.191, 2.1.1.37, 2.1.1.72 L C-5 cytosine-specific DNA methylase
HKPMIKFJ_01596 2.4e-126 rlmI 2.1.1.191, 2.1.1.37, 2.1.1.72 H Methyltransferase
HKPMIKFJ_01597 3.6e-46 L HNH endonuclease
HKPMIKFJ_01598 1.8e-48
HKPMIKFJ_01599 4e-170 L Initiator Replication protein
HKPMIKFJ_01600 4.6e-28
HKPMIKFJ_01601 5.8e-64
HKPMIKFJ_01602 1.3e-44 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKPMIKFJ_01603 4.6e-64 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKPMIKFJ_01604 3.4e-112 ytbE C Aldo keto reductase
HKPMIKFJ_01605 1.9e-141 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HKPMIKFJ_01606 1.2e-250 yfnA E Amino Acid
HKPMIKFJ_01607 4.4e-250 M domain protein
HKPMIKFJ_01608 7.7e-230 XK27_00720 S Leucine-rich repeat (LRR) protein
HKPMIKFJ_01609 8.4e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKPMIKFJ_01610 6.9e-101 ahpC 1.11.1.15 O Peroxiredoxin
HKPMIKFJ_01611 2.7e-55
HKPMIKFJ_01612 9.3e-110 ylbE GM NAD(P)H-binding
HKPMIKFJ_01613 3.7e-44
HKPMIKFJ_01614 1.5e-70 K Helix-turn-helix XRE-family like proteins
HKPMIKFJ_01616 5.4e-20
HKPMIKFJ_01617 2.7e-34
HKPMIKFJ_01619 1.4e-27 K Helix-turn-helix XRE-family like proteins
HKPMIKFJ_01620 9.3e-82 P CorA-like Mg2+ transporter protein
HKPMIKFJ_01621 3.2e-134 XK27_00890 S Domain of unknown function (DUF368)
HKPMIKFJ_01622 3.4e-132 K helix_turn_helix, mercury resistance
HKPMIKFJ_01623 1.7e-221 xylR GK ROK family
HKPMIKFJ_01624 2e-218
HKPMIKFJ_01625 1.1e-42
HKPMIKFJ_01627 0.0 oatA I Acyltransferase
HKPMIKFJ_01628 6.6e-123
HKPMIKFJ_01629 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HKPMIKFJ_01630 4.5e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HKPMIKFJ_01631 1.7e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKPMIKFJ_01632 2.4e-34
HKPMIKFJ_01633 1.4e-93 K helix_turn_helix multiple antibiotic resistance protein
HKPMIKFJ_01634 1.1e-245 xylP1 G MFS/sugar transport protein
HKPMIKFJ_01635 1.3e-98 S Protein of unknown function (DUF1440)
HKPMIKFJ_01636 0.0 uvrA2 L ABC transporter
HKPMIKFJ_01637 1.9e-65 S Tautomerase enzyme
HKPMIKFJ_01638 6.9e-260
HKPMIKFJ_01639 9.3e-221
HKPMIKFJ_01640 2.1e-109 opuCD P Binding-protein-dependent transport system inner membrane component
HKPMIKFJ_01641 1.1e-175 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKPMIKFJ_01642 8e-106 opuCB E ABC transporter permease
HKPMIKFJ_01643 1.2e-222 opuCA E ABC transporter, ATP-binding protein
HKPMIKFJ_01644 4.6e-45
HKPMIKFJ_01645 5.9e-222 mdtG EGP Major facilitator Superfamily
HKPMIKFJ_01646 1.6e-182 yfeX P Peroxidase
HKPMIKFJ_01647 3.6e-229 patB 4.4.1.8 E Aminotransferase, class I
HKPMIKFJ_01648 6.2e-109 M Protein of unknown function (DUF3737)
HKPMIKFJ_01649 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKPMIKFJ_01650 8.8e-187 ykoT GT2 M Glycosyl transferase family 2
HKPMIKFJ_01651 2.4e-240 M hydrolase, family 25
HKPMIKFJ_01652 5.3e-105
HKPMIKFJ_01653 3.1e-196 yubA S AI-2E family transporter
HKPMIKFJ_01654 1.6e-160 yclI V FtsX-like permease family
HKPMIKFJ_01655 4.6e-120 yclH V ABC transporter
HKPMIKFJ_01656 0.0 malL 3.2.1.10, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G Alpha amylase, catalytic domain protein
HKPMIKFJ_01657 8.6e-57 K Winged helix DNA-binding domain
HKPMIKFJ_01658 6.1e-137 pnuC H nicotinamide mononucleotide transporter
HKPMIKFJ_01659 2.4e-151 corA P CorA-like Mg2+ transporter protein
HKPMIKFJ_01660 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKPMIKFJ_01661 4.1e-66
HKPMIKFJ_01662 6.5e-43
HKPMIKFJ_01663 2.3e-222 T PhoQ Sensor
HKPMIKFJ_01664 2e-126 K Transcriptional regulatory protein, C terminal
HKPMIKFJ_01665 3e-26
HKPMIKFJ_01666 8.1e-114 ylbE GM NAD(P)H-binding
HKPMIKFJ_01667 9.3e-228 ndh 1.6.99.3 C NADH dehydrogenase
HKPMIKFJ_01668 3.9e-90 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKPMIKFJ_01669 1.7e-102 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_01670 3.5e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HKPMIKFJ_01671 1.6e-100 K Bacterial transcriptional regulator
HKPMIKFJ_01672 1.8e-09
HKPMIKFJ_01673 9.6e-147 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HKPMIKFJ_01674 3.9e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKPMIKFJ_01675 4.5e-127 kdgT P 2-keto-3-deoxygluconate permease
HKPMIKFJ_01676 1.5e-111 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HKPMIKFJ_01677 9.3e-81 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HKPMIKFJ_01678 9e-39
HKPMIKFJ_01679 3.4e-127 IQ reductase
HKPMIKFJ_01680 2.4e-240 mntH P H( )-stimulated, divalent metal cation uptake system
HKPMIKFJ_01681 4.1e-153 S Uncharacterised protein, DegV family COG1307
HKPMIKFJ_01682 5.5e-264 nox C NADH oxidase
HKPMIKFJ_01683 9.4e-186 L PFAM Integrase, catalytic core
HKPMIKFJ_01684 2.3e-56 trxA1 O Belongs to the thioredoxin family
HKPMIKFJ_01685 5.1e-38 yrkD S Metal-sensitive transcriptional repressor
HKPMIKFJ_01686 1.3e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKPMIKFJ_01687 5.1e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKPMIKFJ_01688 9.6e-147 M1-1017
HKPMIKFJ_01689 3.7e-162 I Carboxylesterase family
HKPMIKFJ_01690 5.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKPMIKFJ_01691 1.7e-159
HKPMIKFJ_01692 2.3e-248 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKPMIKFJ_01693 5.2e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HKPMIKFJ_01694 2.8e-154 lysR5 K LysR substrate binding domain
HKPMIKFJ_01695 8.4e-143 yxaA S membrane transporter protein
HKPMIKFJ_01696 2e-56 ywjH S Protein of unknown function (DUF1634)
HKPMIKFJ_01697 7.8e-140 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HKPMIKFJ_01698 1.2e-225 mdtG EGP Major facilitator Superfamily
HKPMIKFJ_01699 2.8e-96 2.7.6.5 S RelA SpoT domain protein
HKPMIKFJ_01700 1.8e-27 S Protein of unknown function (DUF2929)
HKPMIKFJ_01701 7.2e-169 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKPMIKFJ_01703 0.0 S membrane
HKPMIKFJ_01704 9.1e-119 K cheY-homologous receiver domain
HKPMIKFJ_01705 2.5e-234 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HKPMIKFJ_01706 2e-180 malR K Transcriptional regulator, LacI family
HKPMIKFJ_01707 8.6e-254 malT G Major Facilitator
HKPMIKFJ_01708 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HKPMIKFJ_01709 4.6e-76
HKPMIKFJ_01710 2.3e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKPMIKFJ_01711 4.2e-152 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HKPMIKFJ_01712 2.2e-151 S Alpha/beta hydrolase of unknown function (DUF915)
HKPMIKFJ_01713 4.8e-151 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HKPMIKFJ_01714 4.6e-64 K MarR family
HKPMIKFJ_01715 3.9e-246 yclG M Parallel beta-helix repeats
HKPMIKFJ_01716 1.5e-71 spx4 1.20.4.1 P ArsC family
HKPMIKFJ_01717 5.2e-131 iap CBM50 M NlpC/P60 family
HKPMIKFJ_01718 7.2e-139 K acetyltransferase
HKPMIKFJ_01719 1e-287 E dipeptidase activity
HKPMIKFJ_01720 1e-96 S membrane transporter protein
HKPMIKFJ_01721 2.6e-124 IQ Enoyl-(Acyl carrier protein) reductase
HKPMIKFJ_01722 4.2e-133 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKPMIKFJ_01723 1.2e-152 1.6.5.2 GM NmrA-like family
HKPMIKFJ_01724 1.5e-69 K Transcriptional regulator
HKPMIKFJ_01725 0.0 2.7.8.12 M glycerophosphotransferase
HKPMIKFJ_01726 6.4e-168
HKPMIKFJ_01727 6.3e-63 K Transcriptional regulator, HxlR family
HKPMIKFJ_01728 5.1e-202 ytbD EGP Major facilitator Superfamily
HKPMIKFJ_01729 4.7e-182 S Aldo keto reductase
HKPMIKFJ_01730 1.8e-136 cysA V ABC transporter, ATP-binding protein
HKPMIKFJ_01731 0.0 Q FtsX-like permease family
HKPMIKFJ_01732 3.5e-61 gntR1 K Transcriptional regulator, GntR family
HKPMIKFJ_01733 1.3e-69 S Iron-sulphur cluster biosynthesis
HKPMIKFJ_01734 1e-187 sdrF M Collagen binding domain
HKPMIKFJ_01735 0.0 cadA P P-type ATPase
HKPMIKFJ_01736 6.9e-119 S SNARE associated Golgi protein
HKPMIKFJ_01737 0.0 mco Q Multicopper oxidase
HKPMIKFJ_01738 2.7e-52 czrA K Transcriptional regulator, ArsR family
HKPMIKFJ_01739 1.1e-102 P Cadmium resistance transporter
HKPMIKFJ_01740 1e-158 MA20_14895 S Conserved hypothetical protein 698
HKPMIKFJ_01741 2.9e-154 K LysR substrate binding domain
HKPMIKFJ_01742 1.9e-209 norA EGP Major facilitator Superfamily
HKPMIKFJ_01743 4.4e-155 K helix_turn_helix, arabinose operon control protein
HKPMIKFJ_01744 4.5e-311 ybiT S ABC transporter, ATP-binding protein
HKPMIKFJ_01745 2.7e-166 ydcZ S Putative inner membrane exporter, YdcZ
HKPMIKFJ_01746 1.3e-176 xopQ 3.2.2.1, 3.2.2.8 F inosine-uridine preferring nucleoside hydrolase
HKPMIKFJ_01747 1.5e-19
HKPMIKFJ_01748 0.0 2.8.2.22 M Arylsulfotransferase Ig-like domain
HKPMIKFJ_01749 9.6e-132 XK27_07210 6.1.1.6 S B3/4 domain
HKPMIKFJ_01750 3.5e-121 S Protein of unknown function (DUF975)
HKPMIKFJ_01751 2.1e-61 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HKPMIKFJ_01752 1.9e-161 ytrB V ABC transporter, ATP-binding protein
HKPMIKFJ_01753 6e-174
HKPMIKFJ_01754 8.4e-193 KT Putative sugar diacid recognition
HKPMIKFJ_01755 2.7e-212 EG GntP family permease
HKPMIKFJ_01756 5.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HKPMIKFJ_01757 8.4e-268 ydbT S Bacterial PH domain
HKPMIKFJ_01758 7.8e-85 S Bacterial PH domain
HKPMIKFJ_01759 4.9e-78 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HKPMIKFJ_01760 1.6e-255 U Belongs to the purine-cytosine permease (2.A.39) family
HKPMIKFJ_01761 9.8e-36
HKPMIKFJ_01762 8.6e-276 frvR K Mga helix-turn-helix domain
HKPMIKFJ_01763 2.3e-251 S Uncharacterized protein conserved in bacteria (DUF2252)
HKPMIKFJ_01764 6.6e-60 K Winged helix DNA-binding domain
HKPMIKFJ_01765 7.6e-30
HKPMIKFJ_01766 5.4e-240 mntH P H( )-stimulated, divalent metal cation uptake system
HKPMIKFJ_01767 5.8e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKPMIKFJ_01768 3.8e-73 3.6.4.12 L UvrD/REP helicase N-terminal domain
HKPMIKFJ_01769 2.8e-123 L AAA ATPase domain
HKPMIKFJ_01770 3.4e-13 K helix_turn_helix, mercury resistance
HKPMIKFJ_01771 2.9e-122 dedA S SNARE-like domain protein
HKPMIKFJ_01772 2.5e-65 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HKPMIKFJ_01773 7.2e-11 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HKPMIKFJ_01774 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKPMIKFJ_01775 5.2e-71 yugI 5.3.1.9 J general stress protein
HKPMIKFJ_01776 1.7e-156 L Integrase core domain
HKPMIKFJ_01777 1.7e-38 L Transposase and inactivated derivatives
HKPMIKFJ_01778 4.4e-18
HKPMIKFJ_01779 6e-09 S Transglycosylase associated protein
HKPMIKFJ_01782 4.5e-09 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKPMIKFJ_01791 1.2e-07
HKPMIKFJ_01801 2.8e-232 N Uncharacterized conserved protein (DUF2075)
HKPMIKFJ_01802 9e-92 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HKPMIKFJ_01803 6e-137 yhfI S Metallo-beta-lactamase superfamily
HKPMIKFJ_01804 1e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKPMIKFJ_01805 1e-112 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKPMIKFJ_01806 7.9e-106 T EAL domain
HKPMIKFJ_01807 4.2e-89
HKPMIKFJ_01808 2e-247 pgaC GT2 M Glycosyl transferase
HKPMIKFJ_01809 5.9e-100 ytqB J Putative rRNA methylase
HKPMIKFJ_01810 2.5e-115 pgpB1 3.6.1.27 I Acid phosphatase homologues
HKPMIKFJ_01811 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKPMIKFJ_01812 5.9e-47
HKPMIKFJ_01813 5.5e-121 P ABC-type multidrug transport system ATPase component
HKPMIKFJ_01814 7.6e-143 S NADPH-dependent FMN reductase
HKPMIKFJ_01815 1.6e-49
HKPMIKFJ_01816 2.4e-295 ytgP S Polysaccharide biosynthesis protein
HKPMIKFJ_01817 1.6e-123 rluB 5.4.99.19, 5.4.99.20, 5.4.99.21, 5.4.99.22 J pseudouridine synthase activity
HKPMIKFJ_01818 3.6e-146 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKPMIKFJ_01819 3.1e-267 pepV 3.5.1.18 E dipeptidase PepV
HKPMIKFJ_01820 1e-82 uspA T Belongs to the universal stress protein A family
HKPMIKFJ_01821 1.2e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HKPMIKFJ_01822 1.8e-243 cycA E Amino acid permease
HKPMIKFJ_01823 2e-55 ytzB S Small secreted protein
HKPMIKFJ_01824 4e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKPMIKFJ_01825 1.4e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKPMIKFJ_01826 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HKPMIKFJ_01827 4.3e-258 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HKPMIKFJ_01828 1.5e-132 pnuC H nicotinamide mononucleotide transporter
HKPMIKFJ_01829 7.1e-119 ybhL S Belongs to the BI1 family
HKPMIKFJ_01830 9.4e-237 F Permease
HKPMIKFJ_01831 4.9e-262 guaD 3.5.4.3 F Amidohydrolase family
HKPMIKFJ_01832 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKPMIKFJ_01833 3.3e-163 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKPMIKFJ_01834 1.8e-110 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKPMIKFJ_01835 7.8e-88 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKPMIKFJ_01836 1e-243 dnaB L replication initiation and membrane attachment
HKPMIKFJ_01837 2.9e-165 dnaI L Primosomal protein DnaI
HKPMIKFJ_01838 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKPMIKFJ_01839 4.4e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKPMIKFJ_01840 5.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HKPMIKFJ_01841 3.7e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKPMIKFJ_01842 2.1e-113 S regulation of response to stimulus
HKPMIKFJ_01843 3.2e-103 yqeG S HAD phosphatase, family IIIA
HKPMIKFJ_01844 1.9e-222 yqeH S Ribosome biogenesis GTPase YqeH
HKPMIKFJ_01845 1.3e-48 yhbY J RNA-binding protein
HKPMIKFJ_01846 5.9e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKPMIKFJ_01847 1.8e-107 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HKPMIKFJ_01848 1.6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKPMIKFJ_01849 4.5e-140 yqeM Q Methyltransferase
HKPMIKFJ_01850 6.6e-215 ylbM S Belongs to the UPF0348 family
HKPMIKFJ_01851 1.9e-95 yceD S Uncharacterized ACR, COG1399
HKPMIKFJ_01852 6.9e-29 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HKPMIKFJ_01853 2.3e-145 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HKPMIKFJ_01854 1.5e-52 K Transcriptional regulator, ArsR family
HKPMIKFJ_01855 3.2e-113 zmp3 O Zinc-dependent metalloprotease
HKPMIKFJ_01856 1.9e-194 adhP 1.1.1.1 C alcohol dehydrogenase
HKPMIKFJ_01857 2.8e-120 K response regulator
HKPMIKFJ_01858 9.3e-292 arlS 2.7.13.3 T Histidine kinase
HKPMIKFJ_01859 1.2e-70 S Protein of unknown function (DUF1093)
HKPMIKFJ_01860 3.1e-135 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKPMIKFJ_01861 8.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HKPMIKFJ_01862 9.4e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKPMIKFJ_01863 5.2e-92 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKPMIKFJ_01864 3.9e-68 yodB K Transcriptional regulator, HxlR family
HKPMIKFJ_01865 5.8e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKPMIKFJ_01866 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKPMIKFJ_01867 1.9e-206 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKPMIKFJ_01868 1e-119 udk 2.7.1.48 F Cytidine monophosphokinase
HKPMIKFJ_01869 6.3e-71 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKPMIKFJ_01870 1.7e-56 yneR S Belongs to the HesB IscA family
HKPMIKFJ_01871 0.0 S membrane
HKPMIKFJ_01872 1.8e-25 CP_0775 S Domain of unknown function (DUF378)
HKPMIKFJ_01873 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HKPMIKFJ_01874 2.5e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKPMIKFJ_01875 1.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKPMIKFJ_01876 2e-118 gluP 3.4.21.105 S Peptidase, S54 family
HKPMIKFJ_01877 1.2e-35 yqgQ S Bacterial protein of unknown function (DUF910)
HKPMIKFJ_01878 8.9e-181 glk 2.7.1.2 G Glucokinase
HKPMIKFJ_01879 2.1e-70 yqhL P Rhodanese-like protein
HKPMIKFJ_01880 3.1e-23 WQ51_02665 S Protein of unknown function (DUF3042)
HKPMIKFJ_01881 1.9e-141 glpQ 3.1.4.46 C phosphodiesterase
HKPMIKFJ_01882 1e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKPMIKFJ_01883 2.1e-64 glnR K Transcriptional regulator
HKPMIKFJ_01884 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
HKPMIKFJ_01885 8.1e-157
HKPMIKFJ_01886 1.8e-178
HKPMIKFJ_01887 1.4e-95 dut S Protein conserved in bacteria
HKPMIKFJ_01888 5e-93 K Transcriptional regulator
HKPMIKFJ_01889 3.4e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HKPMIKFJ_01890 2.2e-57 ysxB J Cysteine protease Prp
HKPMIKFJ_01891 1.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HKPMIKFJ_01892 2e-189 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HKPMIKFJ_01893 1.3e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKPMIKFJ_01894 4.8e-73 yqhY S Asp23 family, cell envelope-related function
HKPMIKFJ_01895 7.2e-74 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKPMIKFJ_01896 1.5e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKPMIKFJ_01897 6.1e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKPMIKFJ_01898 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKPMIKFJ_01899 9.2e-164 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKPMIKFJ_01900 2.6e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HKPMIKFJ_01901 1.1e-75 argR K Regulates arginine biosynthesis genes
HKPMIKFJ_01902 1.7e-307 recN L May be involved in recombinational repair of damaged DNA
HKPMIKFJ_01903 5.4e-66 M domain protein
HKPMIKFJ_01905 7.6e-52
HKPMIKFJ_01906 3.3e-104 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HKPMIKFJ_01907 4.9e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKPMIKFJ_01908 3.8e-213 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKPMIKFJ_01909 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKPMIKFJ_01910 1.8e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKPMIKFJ_01911 1.9e-226 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKPMIKFJ_01912 1.4e-128 stp 3.1.3.16 T phosphatase
HKPMIKFJ_01913 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HKPMIKFJ_01914 4.7e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKPMIKFJ_01915 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HKPMIKFJ_01916 1.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HKPMIKFJ_01917 8.3e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HKPMIKFJ_01918 5.2e-57 asp S Asp23 family, cell envelope-related function
HKPMIKFJ_01919 2.4e-311 yloV S DAK2 domain fusion protein YloV
HKPMIKFJ_01920 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKPMIKFJ_01921 6.8e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKPMIKFJ_01922 6.4e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKPMIKFJ_01923 2.8e-128 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKPMIKFJ_01924 0.0 smc D Required for chromosome condensation and partitioning
HKPMIKFJ_01925 1.4e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKPMIKFJ_01926 2.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKPMIKFJ_01927 8.3e-207 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKPMIKFJ_01928 0.0 pacL 3.6.3.8 P P-type ATPase
HKPMIKFJ_01929 6.9e-212 3.1.3.1 S associated with various cellular activities
HKPMIKFJ_01930 2e-228 S Putative metallopeptidase domain
HKPMIKFJ_01931 6.1e-48
HKPMIKFJ_01932 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HKPMIKFJ_01933 1.9e-40 ylqC S Belongs to the UPF0109 family
HKPMIKFJ_01934 4.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKPMIKFJ_01935 4.5e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HKPMIKFJ_01936 2.7e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKPMIKFJ_01937 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKPMIKFJ_01938 6.2e-79 marR K Transcriptional regulator
HKPMIKFJ_01939 2.6e-180 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKPMIKFJ_01940 1.9e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKPMIKFJ_01941 1.8e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HKPMIKFJ_01942 3.2e-122 IQ reductase
HKPMIKFJ_01943 5.2e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKPMIKFJ_01944 6.7e-72 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKPMIKFJ_01945 5.5e-71 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HKPMIKFJ_01946 1.2e-266 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HKPMIKFJ_01947 2.8e-154 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKPMIKFJ_01948 1.6e-140 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HKPMIKFJ_01949 1.3e-126 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HKPMIKFJ_01950 2e-138 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKPMIKFJ_01951 9.3e-84 bioY S BioY family
HKPMIKFJ_01952 9.9e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HKPMIKFJ_01953 6.5e-138 yceJ EGP Major facilitator Superfamily
HKPMIKFJ_01954 1.5e-27 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKPMIKFJ_01955 3.4e-41 entB 3.5.1.19 Q Isochorismatase family
HKPMIKFJ_01956 2.3e-62 S Leucine-rich repeat (LRR) protein
HKPMIKFJ_01957 3.6e-127
HKPMIKFJ_01958 9.9e-91 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKPMIKFJ_01959 2e-132 gntR1 K UbiC transcription regulator-associated domain protein
HKPMIKFJ_01960 1.3e-109 O Zinc-dependent metalloprotease
HKPMIKFJ_01961 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKPMIKFJ_01962 3.3e-71
HKPMIKFJ_01963 3.4e-135 plnC K LytTr DNA-binding domain
HKPMIKFJ_01964 7.9e-204 2.7.13.3 T GHKL domain
HKPMIKFJ_01965 3e-211 2.1.1.80, 2.7.13.3, 3.1.1.61 T protein histidine kinase activity
HKPMIKFJ_01966 1.1e-127 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HKPMIKFJ_01968 1.1e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKPMIKFJ_01969 6.2e-76 uspA T universal stress protein
HKPMIKFJ_01970 1.5e-54 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKPMIKFJ_01971 2.8e-177 norB EGP Major Facilitator
HKPMIKFJ_01972 8.1e-51 K transcriptional regulator
HKPMIKFJ_01973 0.0 oppA1 E ABC transporter substrate-binding protein
HKPMIKFJ_01974 1e-173 oppC EP Binding-protein-dependent transport system inner membrane component
HKPMIKFJ_01975 9.8e-180 oppB P ABC transporter permease
HKPMIKFJ_01976 1.6e-177 oppF P Belongs to the ABC transporter superfamily
HKPMIKFJ_01977 6.9e-192 oppD P Belongs to the ABC transporter superfamily
HKPMIKFJ_01978 1.6e-79 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HKPMIKFJ_01979 3.9e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HKPMIKFJ_01980 2.3e-69
HKPMIKFJ_01981 2.4e-49
HKPMIKFJ_01982 6.8e-17
HKPMIKFJ_01984 3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HKPMIKFJ_01985 4.8e-290 xylB 2.7.1.12, 2.7.1.16, 2.7.1.17 G Xylulose kinase
HKPMIKFJ_01986 1.1e-224 xylT EGP Major facilitator Superfamily
HKPMIKFJ_01987 4.3e-141 IQ reductase
HKPMIKFJ_01988 2.6e-64 frataxin S Domain of unknown function (DU1801)
HKPMIKFJ_01989 0.0 S membrane
HKPMIKFJ_01990 1.3e-88 uspA T universal stress protein
HKPMIKFJ_01991 5.7e-94 yxkA S Phosphatidylethanolamine-binding protein
HKPMIKFJ_01992 1e-215 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HKPMIKFJ_01993 9.6e-122 kcsA P Ion channel
HKPMIKFJ_01994 2.3e-49
HKPMIKFJ_01995 3.5e-171 C Aldo keto reductase
HKPMIKFJ_01996 2.4e-68
HKPMIKFJ_01997 3e-93 Z012_06855 S Acetyltransferase (GNAT) family
HKPMIKFJ_01998 2.7e-250 nhaC C Na H antiporter NhaC
HKPMIKFJ_01999 2.3e-190 S Membrane transport protein
HKPMIKFJ_02000 2.7e-188 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKPMIKFJ_02001 4.6e-267 yufL 2.7.13.3 T Single cache domain 3
HKPMIKFJ_02002 1.3e-123 malR3 K cheY-homologous receiver domain
HKPMIKFJ_02003 1.2e-172 S ABC-2 family transporter protein
HKPMIKFJ_02004 9.3e-101 XK27_06935 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_02005 2.4e-95 yliE T Putative diguanylate phosphodiesterase
HKPMIKFJ_02006 1.3e-87 M Belongs to the glycosyl hydrolase 28 family
HKPMIKFJ_02007 2.9e-93 wecD K Acetyltransferase (GNAT) family
HKPMIKFJ_02009 9.8e-85 F NUDIX domain
HKPMIKFJ_02011 1.2e-102 padC Q Phenolic acid decarboxylase
HKPMIKFJ_02012 2.2e-82 padR K Virulence activator alpha C-term
HKPMIKFJ_02013 2e-74 elaA S Gnat family
HKPMIKFJ_02014 2.1e-79 yybA 2.3.1.57 K Transcriptional regulator
HKPMIKFJ_02020 1.9e-71
HKPMIKFJ_02021 4.4e-87 P Cadmium resistance transporter
HKPMIKFJ_02022 1e-119 sirR K Helix-turn-helix diphteria tox regulatory element
HKPMIKFJ_02023 1.5e-71 T Universal stress protein family
HKPMIKFJ_02024 8.3e-285 mntH P H( )-stimulated, divalent metal cation uptake system
HKPMIKFJ_02025 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKPMIKFJ_02026 1.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKPMIKFJ_02027 1.8e-240 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKPMIKFJ_02028 1.5e-121 GM NmrA-like family
HKPMIKFJ_02029 2.1e-97 fadR K Bacterial regulatory proteins, tetR family
HKPMIKFJ_02030 1.2e-179 D Alpha beta
HKPMIKFJ_02031 4.1e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HKPMIKFJ_02032 5.7e-166 I Alpha beta
HKPMIKFJ_02033 5.9e-127 O Pro-kumamolisin, activation domain
HKPMIKFJ_02034 6e-199 O Pro-kumamolisin, activation domain
HKPMIKFJ_02035 1.2e-114 S Membrane
HKPMIKFJ_02036 6.9e-133 puuD S peptidase C26
HKPMIKFJ_02037 3.7e-38
HKPMIKFJ_02038 1.4e-113 magIII L Base excision DNA repair protein, HhH-GPD family
HKPMIKFJ_02039 5.7e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKPMIKFJ_02041 1.2e-76 ssuB P ATPases associated with a variety of cellular activities
HKPMIKFJ_02042 6.6e-116 ssuC U Binding-protein-dependent transport system inner membrane component
HKPMIKFJ_02043 1e-195 M NlpC/P60 family
HKPMIKFJ_02044 9.2e-161 G Peptidase_C39 like family
HKPMIKFJ_02045 1.1e-242 3.2.1.21 GH3 G Fibronectin type III-like domain
HKPMIKFJ_02046 2.6e-78 K AraC-like ligand binding domain
HKPMIKFJ_02047 6.4e-250 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
HKPMIKFJ_02048 2.9e-147 blt G MFS/sugar transport protein
HKPMIKFJ_02049 2e-215 srfJ1 3.2.1.45 GH30 M Belongs to the glycosyl hydrolase 30 family
HKPMIKFJ_02050 3.8e-104 pncA Q Isochorismatase family
HKPMIKFJ_02051 1e-53 K Transcriptional regulator PadR-like family
HKPMIKFJ_02052 5.3e-73 XK27_06920 S Protein of unknown function (DUF1700)
HKPMIKFJ_02053 2.5e-111 S Putative adhesin
HKPMIKFJ_02054 1.2e-185 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKPMIKFJ_02055 4.9e-221 fabV 1.3.1.44, 1.3.1.9 I NAD(P)H binding domain of trans-2-enoyl-CoA reductase
HKPMIKFJ_02056 5.3e-72 fld C Flavodoxin
HKPMIKFJ_02057 4.3e-97 K Acetyltransferase (GNAT) domain
HKPMIKFJ_02058 6.2e-241 yifK E Amino acid permease
HKPMIKFJ_02059 4e-108
HKPMIKFJ_02060 4.7e-63 S WxL domain surface cell wall-binding
HKPMIKFJ_02061 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HKPMIKFJ_02062 2.9e-224 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HKPMIKFJ_02063 6e-188 adhP 1.1.1.1 C alcohol dehydrogenase
HKPMIKFJ_02064 8.1e-52 lrpA K AsnC family
HKPMIKFJ_02065 1.6e-163 opuBA E ABC transporter, ATP-binding protein
HKPMIKFJ_02066 5.5e-270 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKPMIKFJ_02067 6.4e-12 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKPMIKFJ_02068 1.1e-195 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HKPMIKFJ_02069 1.1e-98 S NADPH-dependent FMN reductase
HKPMIKFJ_02070 1.7e-71 K MarR family
HKPMIKFJ_02071 0.0 pacL1 P P-type ATPase
HKPMIKFJ_02072 1.9e-195 ybiR P Citrate transporter
HKPMIKFJ_02073 2.1e-120 yliE T Putative diguanylate phosphodiesterase
HKPMIKFJ_02074 1.3e-146 2.7.7.65 T diguanylate cyclase
HKPMIKFJ_02075 1.1e-08
HKPMIKFJ_02076 8.9e-56
HKPMIKFJ_02077 0.0 lmrA V ABC transporter, ATP-binding protein
HKPMIKFJ_02078 0.0 yfiC V ABC transporter
HKPMIKFJ_02079 3.1e-192 ampC V Beta-lactamase
HKPMIKFJ_02080 8.6e-133 cobQ S glutamine amidotransferase
HKPMIKFJ_02081 1.5e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HKPMIKFJ_02082 8.5e-110 tdk 2.7.1.21 F thymidine kinase
HKPMIKFJ_02083 3.5e-186 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKPMIKFJ_02084 1.8e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKPMIKFJ_02085 1.8e-187 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKPMIKFJ_02086 1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKPMIKFJ_02087 1.5e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKPMIKFJ_02088 6.1e-126 atpB C it plays a direct role in the translocation of protons across the membrane
HKPMIKFJ_02089 7.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKPMIKFJ_02090 3.4e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKPMIKFJ_02091 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKPMIKFJ_02092 1.6e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKPMIKFJ_02093 3.6e-160 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKPMIKFJ_02094 5.3e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKPMIKFJ_02095 1.1e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HKPMIKFJ_02096 1.3e-32 ywzB S Protein of unknown function (DUF1146)
HKPMIKFJ_02097 9.4e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKPMIKFJ_02098 6e-180 mbl D Cell shape determining protein MreB Mrl
HKPMIKFJ_02099 1.1e-52 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HKPMIKFJ_02100 1.1e-33 S Protein of unknown function (DUF2969)
HKPMIKFJ_02101 1.1e-220 rodA D Belongs to the SEDS family
HKPMIKFJ_02102 9.6e-49 gcsH2 E glycine cleavage
HKPMIKFJ_02103 1.3e-140 f42a O Band 7 protein
HKPMIKFJ_02104 5.6e-175 S Protein of unknown function (DUF2785)
HKPMIKFJ_02105 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HKPMIKFJ_02106 9.3e-289 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HKPMIKFJ_02107 6.3e-157 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HKPMIKFJ_02108 1e-81 usp6 T universal stress protein
HKPMIKFJ_02109 3.2e-41
HKPMIKFJ_02110 8.3e-235 rarA L recombination factor protein RarA
HKPMIKFJ_02111 3.5e-79 yueI S Protein of unknown function (DUF1694)
HKPMIKFJ_02112 1.2e-111 yktB S Belongs to the UPF0637 family
HKPMIKFJ_02113 1.2e-60 KLT serine threonine protein kinase
HKPMIKFJ_02114 4.8e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKPMIKFJ_02115 1.2e-82 ytsP 1.8.4.14 T GAF domain-containing protein
HKPMIKFJ_02116 2.4e-311 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKPMIKFJ_02117 3.2e-214 iscS2 2.8.1.7 E Aminotransferase class V
HKPMIKFJ_02118 5.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKPMIKFJ_02119 1e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKPMIKFJ_02120 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKPMIKFJ_02121 8e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKPMIKFJ_02122 5.6e-118 radC L DNA repair protein
HKPMIKFJ_02123 9.6e-162 mreB D cell shape determining protein MreB
HKPMIKFJ_02124 9.7e-139 mreC M Involved in formation and maintenance of cell shape
HKPMIKFJ_02125 3.2e-92 mreD M rod shape-determining protein MreD
HKPMIKFJ_02126 5.3e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKPMIKFJ_02127 4.1e-147 minD D Belongs to the ParA family
HKPMIKFJ_02128 7.1e-110 glnP P ABC transporter permease
HKPMIKFJ_02129 7.1e-94 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKPMIKFJ_02130 1.4e-158 aatB ET ABC transporter substrate-binding protein
HKPMIKFJ_02131 6.4e-235 ymfF S Peptidase M16 inactive domain protein
HKPMIKFJ_02132 2.3e-245 ymfH S Peptidase M16
HKPMIKFJ_02133 2.6e-65 ymfM S Domain of unknown function (DUF4115)
HKPMIKFJ_02134 1e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKPMIKFJ_02135 2.8e-227 cinA 3.5.1.42 S Belongs to the CinA family
HKPMIKFJ_02136 1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKPMIKFJ_02138 2e-222 rny S Endoribonuclease that initiates mRNA decay
HKPMIKFJ_02139 3.3e-149 ymdB S YmdB-like protein
HKPMIKFJ_02140 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKPMIKFJ_02141 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKPMIKFJ_02142 2.8e-108 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKPMIKFJ_02143 2.5e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKPMIKFJ_02144 1.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKPMIKFJ_02145 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKPMIKFJ_02146 1.1e-26 yajC U Preprotein translocase
HKPMIKFJ_02147 3.5e-181 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKPMIKFJ_02148 2.2e-179 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HKPMIKFJ_02149 1.4e-251 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKPMIKFJ_02150 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKPMIKFJ_02151 1.9e-43 yrzL S Belongs to the UPF0297 family
HKPMIKFJ_02152 1.5e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKPMIKFJ_02153 1.6e-51 yrzB S Belongs to the UPF0473 family
HKPMIKFJ_02154 1.4e-38 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKPMIKFJ_02155 6.4e-88 cvpA S Colicin V production protein
HKPMIKFJ_02156 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKPMIKFJ_02157 2.7e-54 trxA O Belongs to the thioredoxin family
HKPMIKFJ_02158 7.2e-92 yslB S Protein of unknown function (DUF2507)
HKPMIKFJ_02159 1.5e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKPMIKFJ_02160 1.4e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKPMIKFJ_02161 1.9e-97 S Phosphoesterase
HKPMIKFJ_02162 4.6e-85 ykuL S (CBS) domain
HKPMIKFJ_02164 1.5e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKPMIKFJ_02165 8.6e-246 U Major Facilitator Superfamily
HKPMIKFJ_02166 4.1e-156 ykuT M mechanosensitive ion channel
HKPMIKFJ_02167 6.9e-34 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKPMIKFJ_02168 9.5e-43
HKPMIKFJ_02169 2.7e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HKPMIKFJ_02170 1e-179 ccpA K catabolite control protein A
HKPMIKFJ_02171 1.8e-126
HKPMIKFJ_02172 8.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKPMIKFJ_02173 1.2e-264 glnPH2 P ABC transporter permease
HKPMIKFJ_02174 2.6e-132 yebC K Transcriptional regulatory protein
HKPMIKFJ_02175 3.7e-171 comGA NU Type II IV secretion system protein
HKPMIKFJ_02176 7.7e-169 comGB NU type II secretion system
HKPMIKFJ_02177 7.6e-49 comGC U competence protein ComGC
HKPMIKFJ_02178 3.2e-80
HKPMIKFJ_02180 1.1e-74
HKPMIKFJ_02181 7.4e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HKPMIKFJ_02182 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKPMIKFJ_02183 6.1e-255 cycA E Amino acid permease
HKPMIKFJ_02184 1.5e-155 yeaE S Aldo keto
HKPMIKFJ_02185 5.3e-115 S Calcineurin-like phosphoesterase
HKPMIKFJ_02186 5.6e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKPMIKFJ_02187 2.2e-85 yutD S Protein of unknown function (DUF1027)
HKPMIKFJ_02188 1.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKPMIKFJ_02189 4.2e-115 S Protein of unknown function (DUF1461)
HKPMIKFJ_02190 5.9e-88 S WxL domain surface cell wall-binding
HKPMIKFJ_02191 9.9e-32 XK27_00720 S Leucine-rich repeat (LRR) protein
HKPMIKFJ_02192 1.9e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKPMIKFJ_02193 1.3e-30 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKPMIKFJ_02194 6.5e-227 pbuG S permease
HKPMIKFJ_02195 2e-180 iolS C Aldo keto reductase
HKPMIKFJ_02196 7.4e-101 GM NAD(P)H-binding
HKPMIKFJ_02197 7e-57
HKPMIKFJ_02198 3.4e-183 xynD 3.5.1.104 G polysaccharide deacetylase
HKPMIKFJ_02199 2.7e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HKPMIKFJ_02200 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKPMIKFJ_02201 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HKPMIKFJ_02202 2.9e-165
HKPMIKFJ_02203 3.3e-138 K Helix-turn-helix domain
HKPMIKFJ_02205 6.6e-95 qorB 1.6.5.2 GM NmrA-like family
HKPMIKFJ_02206 6.4e-70 K Transcriptional regulator
HKPMIKFJ_02207 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HKPMIKFJ_02208 2.4e-170 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HKPMIKFJ_02209 2e-80 1.1.1.219 GM Male sterility protein
HKPMIKFJ_02210 4.9e-50 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_02211 2.6e-27 K helix_turn_helix, mercury resistance
HKPMIKFJ_02212 7.6e-62 yliE T EAL domain
HKPMIKFJ_02213 1.6e-101 S Alpha beta hydrolase
HKPMIKFJ_02214 3.6e-77 GM NmrA-like family
HKPMIKFJ_02215 4.2e-56 adhR K MerR, DNA binding
HKPMIKFJ_02216 5.2e-49 C Flavodoxin
HKPMIKFJ_02217 2.6e-178 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HKPMIKFJ_02219 4.8e-138 S Alpha/beta hydrolase family
HKPMIKFJ_02220 2.3e-38 T Cyclic nucleotide-binding protein
HKPMIKFJ_02221 5.5e-64 1.6.5.2 S NADPH-dependent FMN reductase
HKPMIKFJ_02222 7.5e-87 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKPMIKFJ_02223 1.9e-38 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M MucBP domain
HKPMIKFJ_02224 9.2e-109 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M MucBP domain
HKPMIKFJ_02225 4.6e-72 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
HKPMIKFJ_02226 3.7e-39 N Uncharacterized conserved protein (DUF2075)
HKPMIKFJ_02227 2.1e-157 1.1.1.65 C Aldo keto reductase
HKPMIKFJ_02228 2.2e-87
HKPMIKFJ_02229 1.9e-214 yttB EGP Major facilitator Superfamily
HKPMIKFJ_02230 2.3e-243 glpT G Major Facilitator Superfamily
HKPMIKFJ_02231 1.7e-134 nfrA 1.5.1.39 C nitroreductase
HKPMIKFJ_02232 2.6e-85 nrdI F Belongs to the NrdI family
HKPMIKFJ_02233 5.4e-257 S ATPases associated with a variety of cellular activities
HKPMIKFJ_02234 1e-249 lmrB EGP Major facilitator Superfamily
HKPMIKFJ_02236 7.7e-143 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKPMIKFJ_02237 6.2e-174 K Transcriptional regulator, LacI family
HKPMIKFJ_02238 9.7e-242 yhdP S Transporter associated domain
HKPMIKFJ_02239 7.6e-61
HKPMIKFJ_02240 1.4e-74 hsp O Belongs to the small heat shock protein (HSP20) family
HKPMIKFJ_02241 9.2e-262 yjeM E Amino Acid
HKPMIKFJ_02242 1.1e-161 ytbE 1.1.1.346 S Aldo keto reductase
HKPMIKFJ_02244 0.0 yfgQ P E1-E2 ATPase
HKPMIKFJ_02245 2.2e-93 M1-874 K Domain of unknown function (DUF1836)
HKPMIKFJ_02248 0.0 glpQ 3.1.4.46 C phosphodiesterase
HKPMIKFJ_02249 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HKPMIKFJ_02250 6.2e-36 M LysM domain protein
HKPMIKFJ_02251 1.1e-54 M LysM domain protein
HKPMIKFJ_02253 2.5e-56 M LysM domain
HKPMIKFJ_02254 1.4e-161 yteR 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HKPMIKFJ_02255 1.1e-246 melB1_1 G MFS/sugar transport protein
HKPMIKFJ_02256 6.5e-95 G Xylose isomerase-like TIM barrel
HKPMIKFJ_02257 7.9e-153 picA 3.2.1.67 G Glycosyl hydrolases family 28
HKPMIKFJ_02259 1.9e-95 K Bacterial regulatory proteins, tetR family
HKPMIKFJ_02260 6.4e-167 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HKPMIKFJ_02261 2.2e-174 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HKPMIKFJ_02262 1.7e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKPMIKFJ_02263 7.6e-51 DR0488 S 3D domain
HKPMIKFJ_02264 8e-283 M Exporter of polyketide antibiotics
HKPMIKFJ_02265 8.8e-167 yjjC V ABC transporter
HKPMIKFJ_02266 1.6e-117 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKPMIKFJ_02267 1.5e-247 V Polysaccharide biosynthesis C-terminal domain
HKPMIKFJ_02268 7e-283 uxaC 5.3.1.12 G glucuronate isomerase
HKPMIKFJ_02269 1.4e-259 gph G MFS/sugar transport protein
HKPMIKFJ_02270 0.0 yicI 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HKPMIKFJ_02271 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HKPMIKFJ_02272 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
HKPMIKFJ_02273 5.6e-166 yqhA G Aldose 1-epimerase
HKPMIKFJ_02274 6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
HKPMIKFJ_02275 7e-189 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKPMIKFJ_02276 1.3e-303 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
HKPMIKFJ_02277 1.1e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HKPMIKFJ_02278 2.6e-129 kdgR K FCD domain
HKPMIKFJ_02279 1.8e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HKPMIKFJ_02280 1.7e-182 exuR K Periplasmic binding protein domain
HKPMIKFJ_02281 7.8e-277 yjmB G MFS/sugar transport protein
HKPMIKFJ_02282 4.8e-309 5.1.2.7 S tagaturonate epimerase
HKPMIKFJ_02283 4e-294 uxaC 5.3.1.12 G glucuronate isomerase
HKPMIKFJ_02284 1.8e-226 S module of peptide synthetase
HKPMIKFJ_02286 3.4e-250 EGP Major facilitator Superfamily
HKPMIKFJ_02287 2.5e-20 S Protein of unknown function (DUF3278)
HKPMIKFJ_02288 2.2e-19 K Helix-turn-helix XRE-family like proteins
HKPMIKFJ_02290 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HKPMIKFJ_02291 5.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKPMIKFJ_02292 1.8e-69 K Transcriptional regulator
HKPMIKFJ_02293 4.3e-74 elaA S Gnat family
HKPMIKFJ_02294 4e-46
HKPMIKFJ_02295 8.9e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKPMIKFJ_02296 1.5e-152 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HKPMIKFJ_02297 1.6e-301 M Mycoplasma protein of unknown function, DUF285
HKPMIKFJ_02298 4.7e-73
HKPMIKFJ_02299 1.3e-25 K Transcriptional
HKPMIKFJ_02300 1e-223 LO Uncharacterized conserved protein (DUF2075)
HKPMIKFJ_02301 0.0 cas3 L CRISPR-associated helicase cas3
HKPMIKFJ_02302 1.3e-198 casA L the current gene model (or a revised gene model) may contain a frame shift
HKPMIKFJ_02303 5.7e-56 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
HKPMIKFJ_02304 2.9e-132 casC L CT1975-like protein
HKPMIKFJ_02305 8.7e-77 casD S CRISPR-associated protein (Cas_Cas5)
HKPMIKFJ_02306 1.6e-80 casE S CRISPR_assoc
HKPMIKFJ_02307 3.9e-136 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKPMIKFJ_02308 2.6e-94 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
HKPMIKFJ_02309 2.3e-116 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HKPMIKFJ_02310 5.2e-26
HKPMIKFJ_02311 7.6e-123
HKPMIKFJ_02312 7.1e-107 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HKPMIKFJ_02313 7.4e-150 pmrB EGP Major facilitator Superfamily
HKPMIKFJ_02314 7.2e-34 pmrB EGP Major facilitator Superfamily
HKPMIKFJ_02315 2.2e-72 S COG NOG18757 non supervised orthologous group
HKPMIKFJ_02316 1.2e-128 K helix_turn_helix, arabinose operon control protein
HKPMIKFJ_02317 0.0 3.2.1.55 GH51 G Right handed beta helix region
HKPMIKFJ_02318 6.4e-208 G Major Facilitator
HKPMIKFJ_02319 1.1e-24
HKPMIKFJ_02320 2.8e-232 EK Aminotransferase, class I
HKPMIKFJ_02321 0.0 tetP J elongation factor G
HKPMIKFJ_02322 1.6e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
HKPMIKFJ_02323 8.3e-111 yhaZ L DNA alkylation repair enzyme
HKPMIKFJ_02324 2.6e-24 yhaZ L DNA alkylation repair enzyme
HKPMIKFJ_02325 2.8e-120 yihL K UTRA
HKPMIKFJ_02326 1.9e-186 yegU O ADP-ribosylglycohydrolase
HKPMIKFJ_02327 8e-252 F Belongs to the purine-cytosine permease (2.A.39) family
HKPMIKFJ_02328 1.8e-148 G Belongs to the carbohydrate kinase PfkB family
HKPMIKFJ_02329 3.5e-171 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HKPMIKFJ_02330 7e-130 S Protein of unknown function
HKPMIKFJ_02331 2.2e-216 naiP EGP Major facilitator Superfamily
HKPMIKFJ_02332 3.8e-120 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKPMIKFJ_02333 1.6e-109 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKPMIKFJ_02334 7.9e-137 S Belongs to the UPF0246 family
HKPMIKFJ_02335 4.6e-11
HKPMIKFJ_02337 1.4e-15 L Transposase
HKPMIKFJ_02338 1.5e-30 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKPMIKFJ_02339 5.9e-304 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HKPMIKFJ_02340 7.5e-155 K Transcriptional regulator
HKPMIKFJ_02341 8.1e-14 yjdF S Protein of unknown function (DUF2992)
HKPMIKFJ_02342 3.5e-12 S Transglycosylase associated protein
HKPMIKFJ_02343 8.8e-38
HKPMIKFJ_02344 9.3e-228 3.6.4.13 M domain protein
HKPMIKFJ_02345 1.9e-299 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HKPMIKFJ_02346 9.1e-156 EG EamA-like transporter family
HKPMIKFJ_02347 4.3e-26
HKPMIKFJ_02348 1.4e-204 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HKPMIKFJ_02351 1.3e-38
HKPMIKFJ_02352 1.3e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKPMIKFJ_02353 0.0 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
HKPMIKFJ_02354 3.3e-127 E Amino acid permease
HKPMIKFJ_02355 2.1e-118 E Amino acid permease
HKPMIKFJ_02356 2.9e-236 nhaC C Na H antiporter NhaC
HKPMIKFJ_02357 5.6e-197 ptcA 2.1.3.3, 2.1.3.6 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKPMIKFJ_02358 1.2e-231 aguD E Amino Acid
HKPMIKFJ_02359 1.1e-216 aguA 3.5.3.12 E agmatine deiminase
HKPMIKFJ_02360 3.7e-163 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HKPMIKFJ_02361 5.2e-217 aguA 3.5.3.12 E agmatine deiminase
HKPMIKFJ_02362 1.2e-146 K Helix-turn-helix domain, rpiR family
HKPMIKFJ_02363 1.1e-161 mleR K LysR family
HKPMIKFJ_02364 3.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HKPMIKFJ_02365 7.4e-167 mleP S Sodium Bile acid symporter family
HKPMIKFJ_02366 6.3e-82 thiW S Thiamine-precursor transporter protein (ThiW)
HKPMIKFJ_02367 5.8e-206 ynfM EGP Major facilitator Superfamily
HKPMIKFJ_02368 1.3e-85 ygfC K Bacterial regulatory proteins, tetR family
HKPMIKFJ_02369 2e-178 hrtB V ABC transporter permease
HKPMIKFJ_02370 5.1e-122 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HKPMIKFJ_02371 6.6e-222 EGP Major facilitator Superfamily
HKPMIKFJ_02372 5.4e-118 S GyrI-like small molecule binding domain
HKPMIKFJ_02373 1.1e-94 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HKPMIKFJ_02374 6.3e-221 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HKPMIKFJ_02375 1.4e-170 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKPMIKFJ_02376 5.8e-118 yeiL K Cyclic nucleotide-monophosphate binding domain
HKPMIKFJ_02377 9.9e-177 rihB 3.2.2.1, 3.2.2.8 F Nucleoside
HKPMIKFJ_02378 1.3e-212 mccF V LD-carboxypeptidase
HKPMIKFJ_02379 3.4e-67 K Transcriptional regulator, HxlR family
HKPMIKFJ_02380 2.4e-12
HKPMIKFJ_02381 4e-223 C Oxidoreductase
HKPMIKFJ_02382 3.9e-184 mdt(A) EGP Major facilitator Superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)