ORF_ID e_value Gene_name EC_number CAZy COGs Description
GLFLGHEG_00001 1e-84 ydfO E COG0346 Lactoylglutathione lyase and related lyases
GLFLGHEG_00002 1.7e-11 mhqP S DoxX
GLFLGHEG_00003 1.1e-41 sleB 3.5.1.28 M Cell wall
GLFLGHEG_00004 4.7e-31 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
GLFLGHEG_00005 9.6e-28 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
GLFLGHEG_00006 5.5e-94 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
GLFLGHEG_00007 1.3e-25 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GLFLGHEG_00008 6.4e-53 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GLFLGHEG_00009 2e-48 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GLFLGHEG_00010 5.9e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GLFLGHEG_00011 1.8e-123 ycbU E Selenocysteine lyase
GLFLGHEG_00012 5.5e-26 ycbU E Selenocysteine lyase
GLFLGHEG_00013 9.8e-46 lmrB EGP the major facilitator superfamily
GLFLGHEG_00014 5.1e-30 lmrB EGP the major facilitator superfamily
GLFLGHEG_00015 1.6e-25 lmrB EGP the major facilitator superfamily
GLFLGHEG_00016 1.4e-30 lmrB EGP the major facilitator superfamily
GLFLGHEG_00017 5.6e-54 yxaF K Transcriptional regulator
GLFLGHEG_00018 1e-106 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GLFLGHEG_00019 1.5e-33 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GLFLGHEG_00020 5.1e-62 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
GLFLGHEG_00021 5.1e-123 yccF K DNA-templated transcriptional preinitiation complex assembly
GLFLGHEG_00022 6.2e-171 yccK C Aldo keto reductase
GLFLGHEG_00023 2.8e-51 ycdA S Domain of unknown function (DUF5105)
GLFLGHEG_00024 2.3e-112 ycdA S Domain of unknown function (DUF5105)
GLFLGHEG_00025 1.6e-263 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
GLFLGHEG_00026 1.6e-263 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
GLFLGHEG_00027 9e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
GLFLGHEG_00028 4.6e-189 S response regulator aspartate phosphatase
GLFLGHEG_00029 3.9e-63 IQ Enoyl-(Acyl carrier protein) reductase
GLFLGHEG_00030 6.5e-44 IQ Enoyl-(Acyl carrier protein) reductase
GLFLGHEG_00031 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
GLFLGHEG_00032 3.5e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
GLFLGHEG_00033 7.2e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GLFLGHEG_00034 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GLFLGHEG_00035 1.6e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLFLGHEG_00036 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
GLFLGHEG_00037 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
GLFLGHEG_00038 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
GLFLGHEG_00039 9.7e-138 terC P Protein of unknown function (DUF475)
GLFLGHEG_00040 0.0 yceG S Putative component of 'biosynthetic module'
GLFLGHEG_00041 8.7e-193 yceH P Belongs to the TelA family
GLFLGHEG_00042 1.2e-214 naiP P Uncharacterised MFS-type transporter YbfB
GLFLGHEG_00043 3.9e-229 proV 3.6.3.32 E glycine betaine
GLFLGHEG_00044 1.6e-138 opuAB P glycine betaine
GLFLGHEG_00045 3.1e-164 opuAC E glycine betaine
GLFLGHEG_00046 1.7e-212 amhX S amidohydrolase
GLFLGHEG_00047 3.1e-230 ycgA S Membrane
GLFLGHEG_00048 4.1e-81 ycgB
GLFLGHEG_00049 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
GLFLGHEG_00050 1.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GLFLGHEG_00051 8.1e-261 mdr EGP Major facilitator Superfamily
GLFLGHEG_00052 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
GLFLGHEG_00053 4.7e-114 ycgF E Lysine exporter protein LysE YggA
GLFLGHEG_00054 1.9e-149 yqcI S YqcI/YcgG family
GLFLGHEG_00055 9.8e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
GLFLGHEG_00056 7.6e-114 ycgI S Domain of unknown function (DUF1989)
GLFLGHEG_00057 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GLFLGHEG_00059 2.4e-84 tmrB S AAA domain
GLFLGHEG_00060 3.1e-16 tmrB S AAA domain
GLFLGHEG_00061 5.6e-149 4.2.1.118 G Xylose isomerase-like TIM barrel
GLFLGHEG_00062 1.4e-232 G COG0477 Permeases of the major facilitator superfamily
GLFLGHEG_00063 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GLFLGHEG_00064 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
GLFLGHEG_00065 1.5e-146 ycgL S Predicted nucleotidyltransferase
GLFLGHEG_00066 2.3e-170 ycgM E Proline dehydrogenase
GLFLGHEG_00067 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
GLFLGHEG_00068 6.4e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLFLGHEG_00069 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
GLFLGHEG_00070 1.3e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GLFLGHEG_00071 1.7e-281 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
GLFLGHEG_00072 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
GLFLGHEG_00073 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GLFLGHEG_00074 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GLFLGHEG_00075 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
GLFLGHEG_00076 2.4e-223 nasA P COG2223 Nitrate nitrite transporter
GLFLGHEG_00077 7.8e-227 yciC S GTPases (G3E family)
GLFLGHEG_00078 3.9e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GLFLGHEG_00079 1.2e-73 yckC S membrane
GLFLGHEG_00080 2.2e-51 S Protein of unknown function (DUF2680)
GLFLGHEG_00081 6.1e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GLFLGHEG_00082 1.8e-66 nin S Competence protein J (ComJ)
GLFLGHEG_00083 1.2e-76 nucA M Deoxyribonuclease NucA/NucB
GLFLGHEG_00084 1.3e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
GLFLGHEG_00085 2.5e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
GLFLGHEG_00086 6.3e-63 hxlR K transcriptional
GLFLGHEG_00087 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_00088 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_00089 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
GLFLGHEG_00090 2e-140 srfAD Q thioesterase
GLFLGHEG_00091 3.6e-249 bamJ E Aminotransferase class I and II
GLFLGHEG_00092 3.8e-64 S YcxB-like protein
GLFLGHEG_00093 6e-169 ycxC EG EamA-like transporter family
GLFLGHEG_00094 3.1e-245 ycxD K GntR family transcriptional regulator
GLFLGHEG_00095 1e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
GLFLGHEG_00096 4.1e-110 yczE S membrane
GLFLGHEG_00097 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GLFLGHEG_00098 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
GLFLGHEG_00099 1.6e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
GLFLGHEG_00100 1.1e-158 bsdA K LysR substrate binding domain
GLFLGHEG_00101 3.2e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GLFLGHEG_00102 2.4e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
GLFLGHEG_00103 2e-38 bsdD 4.1.1.61 S response to toxic substance
GLFLGHEG_00104 1.3e-76 yclD
GLFLGHEG_00105 1.2e-269 dtpT E amino acid peptide transporter
GLFLGHEG_00106 5.2e-280 yclG M Pectate lyase superfamily protein
GLFLGHEG_00108 4.1e-295 gerKA EG Spore germination protein
GLFLGHEG_00109 5.5e-236 gerKC S spore germination
GLFLGHEG_00110 8.7e-196 gerKB F Spore germination protein
GLFLGHEG_00111 7.5e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLFLGHEG_00112 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GLFLGHEG_00113 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
GLFLGHEG_00114 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
GLFLGHEG_00115 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
GLFLGHEG_00116 6.4e-218 yxeP 3.5.1.47 E hydrolase activity
GLFLGHEG_00117 3.2e-253 yxeQ S MmgE/PrpD family
GLFLGHEG_00118 5.6e-121 yclH P ABC transporter
GLFLGHEG_00119 3.6e-223 yclI V ABC transporter (permease) YclI
GLFLGHEG_00120 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GLFLGHEG_00121 1.1e-262 T PhoQ Sensor
GLFLGHEG_00122 1.9e-81 S aspartate phosphatase
GLFLGHEG_00124 5.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
GLFLGHEG_00125 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLFLGHEG_00126 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLFLGHEG_00127 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
GLFLGHEG_00128 2.1e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
GLFLGHEG_00129 2.3e-249 ycnB EGP Major facilitator Superfamily
GLFLGHEG_00130 2.7e-152 ycnC K Transcriptional regulator
GLFLGHEG_00131 8.8e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
GLFLGHEG_00132 1e-44 ycnE S Monooxygenase
GLFLGHEG_00133 1.1e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
GLFLGHEG_00134 3e-262 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GLFLGHEG_00135 5.3e-221 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GLFLGHEG_00136 5.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GLFLGHEG_00137 3.6e-149 glcU U Glucose uptake
GLFLGHEG_00138 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GLFLGHEG_00139 1.7e-97 ycnI S protein conserved in bacteria
GLFLGHEG_00140 4.7e-299 ycnJ P protein, homolog of Cu resistance protein CopC
GLFLGHEG_00141 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
GLFLGHEG_00142 1.6e-55
GLFLGHEG_00143 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
GLFLGHEG_00144 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
GLFLGHEG_00145 1.3e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
GLFLGHEG_00146 1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
GLFLGHEG_00148 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GLFLGHEG_00149 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
GLFLGHEG_00150 4.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
GLFLGHEG_00151 3.9e-150 ycsI S Belongs to the D-glutamate cyclase family
GLFLGHEG_00152 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
GLFLGHEG_00153 3.2e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
GLFLGHEG_00154 4e-131 kipR K Transcriptional regulator
GLFLGHEG_00155 9.3e-118 ycsK E anatomical structure formation involved in morphogenesis
GLFLGHEG_00157 5.1e-56 yczJ S biosynthesis
GLFLGHEG_00158 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
GLFLGHEG_00159 1.5e-174 ydhF S Oxidoreductase
GLFLGHEG_00160 0.0 mtlR K transcriptional regulator, MtlR
GLFLGHEG_00161 6.5e-287 ydaB IQ acyl-CoA ligase
GLFLGHEG_00162 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GLFLGHEG_00163 4.6e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
GLFLGHEG_00164 1.2e-114 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GLFLGHEG_00165 1.4e-77 ydaG 1.4.3.5 S general stress protein
GLFLGHEG_00166 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
GLFLGHEG_00167 1.3e-47 ydzA EGP Major facilitator Superfamily
GLFLGHEG_00168 4.3e-74 lrpC K Transcriptional regulator
GLFLGHEG_00169 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GLFLGHEG_00170 1.1e-200 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
GLFLGHEG_00171 1.3e-146 ydaK T Diguanylate cyclase, GGDEF domain
GLFLGHEG_00172 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
GLFLGHEG_00173 8.5e-232 ydaM M Glycosyl transferase family group 2
GLFLGHEG_00174 0.0 ydaN S Bacterial cellulose synthase subunit
GLFLGHEG_00176 0.0 ydaO E amino acid
GLFLGHEG_00177 8e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
GLFLGHEG_00178 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GLFLGHEG_00179 7.5e-66 K acetyltransferase
GLFLGHEG_00181 9.5e-15
GLFLGHEG_00183 1.3e-39 yqbQ 3.2.1.96 G NLP P60 protein
GLFLGHEG_00184 5.9e-34 xkdR S Protein of unknown function (DUF2577)
GLFLGHEG_00185 2.5e-108 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GLFLGHEG_00186 7.5e-16 xkdS S Protein of unknown function (DUF2634)
GLFLGHEG_00187 6.2e-21 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
GLFLGHEG_00189 2.5e-79
GLFLGHEG_00190 5.6e-98
GLFLGHEG_00191 2.1e-39
GLFLGHEG_00192 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
GLFLGHEG_00194 1.9e-33 ydaT
GLFLGHEG_00195 2.4e-71 yvaD S Family of unknown function (DUF5360)
GLFLGHEG_00196 4.1e-54 yvaE P Small Multidrug Resistance protein
GLFLGHEG_00197 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
GLFLGHEG_00199 1.7e-57 ydbB G Cupin domain
GLFLGHEG_00200 1.4e-62 ydbC S Domain of unknown function (DUF4937
GLFLGHEG_00201 2.5e-155 ydbD P Catalase
GLFLGHEG_00202 7.1e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
GLFLGHEG_00203 2.1e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GLFLGHEG_00204 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
GLFLGHEG_00205 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GLFLGHEG_00206 3.2e-160 ydbI S AI-2E family transporter
GLFLGHEG_00207 5e-173 ydbJ V ABC transporter, ATP-binding protein
GLFLGHEG_00208 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GLFLGHEG_00209 2.1e-52 ydbL
GLFLGHEG_00210 4.5e-205 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
GLFLGHEG_00211 1.5e-10 S Fur-regulated basic protein B
GLFLGHEG_00212 5.8e-09 S Fur-regulated basic protein A
GLFLGHEG_00213 1.1e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GLFLGHEG_00214 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GLFLGHEG_00215 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GLFLGHEG_00216 6.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GLFLGHEG_00217 5.3e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GLFLGHEG_00218 2.1e-82 ydbS S Bacterial PH domain
GLFLGHEG_00219 7.5e-264 ydbT S Membrane
GLFLGHEG_00220 4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
GLFLGHEG_00221 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GLFLGHEG_00222 7.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
GLFLGHEG_00223 1.8e-215 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GLFLGHEG_00224 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
GLFLGHEG_00225 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
GLFLGHEG_00226 6.1e-146 rsbR T Positive regulator of sigma-B
GLFLGHEG_00227 1.8e-57 rsbS T antagonist
GLFLGHEG_00228 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
GLFLGHEG_00229 4.6e-188 rsbU 3.1.3.3 KT phosphatase
GLFLGHEG_00230 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
GLFLGHEG_00231 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
GLFLGHEG_00232 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GLFLGHEG_00233 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
GLFLGHEG_00234 0.0 yhgF K COG2183 Transcriptional accessory protein
GLFLGHEG_00235 1.7e-14
GLFLGHEG_00236 7.3e-58 ydcK S Belongs to the SprT family
GLFLGHEG_00244 1.1e-08
GLFLGHEG_00245 3.5e-29 S Doxx family
GLFLGHEG_00246 3.3e-78 K Transcriptional regulator
GLFLGHEG_00247 1.4e-97 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GLFLGHEG_00248 2.8e-96 ywrO 1.6.5.2 S Flavodoxin-like fold
GLFLGHEG_00249 8.8e-230 proP EGP Transporter
GLFLGHEG_00250 1.3e-48 ohrR K Transcriptional regulator
GLFLGHEG_00251 3.9e-29 S Domain of unknown function with cystatin-like fold (DUF4467)
GLFLGHEG_00252 3.9e-33 S Domain of unknown function with cystatin-like fold (DUF4467)
GLFLGHEG_00253 5.1e-72 maoC I N-terminal half of MaoC dehydratase
GLFLGHEG_00254 4.5e-63 yyaQ S YjbR
GLFLGHEG_00255 3.1e-72 ywnA K Transcriptional regulator
GLFLGHEG_00256 5.3e-113 ywnB S NAD(P)H-binding
GLFLGHEG_00258 1.1e-88 K Bacterial regulatory proteins, tetR family
GLFLGHEG_00259 2.6e-111 C Enoyl-(Acyl carrier protein) reductase
GLFLGHEG_00260 2.5e-173 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GLFLGHEG_00261 2e-191 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
GLFLGHEG_00262 1.4e-30 cspL K Cold shock
GLFLGHEG_00263 1e-78 carD K Transcription factor
GLFLGHEG_00264 5.8e-118 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GLFLGHEG_00265 3.7e-102 S Protein of unknown function (DUF2812)
GLFLGHEG_00266 1.3e-51 K Transcriptional regulator PadR-like family
GLFLGHEG_00267 3.1e-181 S Patatin-like phospholipase
GLFLGHEG_00268 1.7e-84 S DinB superfamily
GLFLGHEG_00269 4.6e-61 G Cupin domain
GLFLGHEG_00272 1.3e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
GLFLGHEG_00273 8.9e-46 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GLFLGHEG_00274 6e-23 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GLFLGHEG_00275 9.3e-167 czcD P COG1230 Co Zn Cd efflux system component
GLFLGHEG_00276 1.3e-201 trkA P Oxidoreductase
GLFLGHEG_00278 2.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
GLFLGHEG_00280 2.7e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
GLFLGHEG_00281 3.5e-56 ydeH
GLFLGHEG_00282 1.4e-83 F nucleoside 2-deoxyribosyltransferase
GLFLGHEG_00283 6.2e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GLFLGHEG_00284 3e-147 Q ubiE/COQ5 methyltransferase family
GLFLGHEG_00285 1.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GLFLGHEG_00286 3.4e-233 3.1.3.41 G Haloacid dehalogenase-like hydrolase
GLFLGHEG_00287 2.7e-169 S Sodium Bile acid symporter family
GLFLGHEG_00288 1.2e-202 adhA 1.1.1.1 C alcohol dehydrogenase
GLFLGHEG_00289 3.6e-67 yraB K helix_turn_helix, mercury resistance
GLFLGHEG_00290 5.6e-223 mleN_2 C antiporter
GLFLGHEG_00291 2.7e-263 K helix_turn_helix gluconate operon transcriptional repressor
GLFLGHEG_00292 3.5e-114 paiB K Transcriptional regulator
GLFLGHEG_00294 3.8e-105 ksgA1 I Ribosomal RNA adenine dimethylase
GLFLGHEG_00295 3.5e-123 T Transcriptional regulator
GLFLGHEG_00296 6.4e-188 T PhoQ Sensor
GLFLGHEG_00297 3.5e-101 S SNARE associated Golgi protein
GLFLGHEG_00298 8.1e-176 ydeR EGP Major facilitator Superfamily
GLFLGHEG_00299 1.3e-102 ydeS K Transcriptional regulator
GLFLGHEG_00300 8.2e-157 ydeK EG -transporter
GLFLGHEG_00301 2.4e-259 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GLFLGHEG_00302 4.7e-48 yraD M Spore coat protein
GLFLGHEG_00303 3.1e-24 yraE
GLFLGHEG_00304 7.4e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GLFLGHEG_00305 1.4e-62 yraF M Spore coat protein
GLFLGHEG_00306 3.8e-35 yraG
GLFLGHEG_00307 2.5e-134 puuD S Peptidase C26
GLFLGHEG_00308 2.3e-298 expZ S ABC transporter
GLFLGHEG_00309 6.5e-101 ynaD J Acetyltransferase (GNAT) domain
GLFLGHEG_00310 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
GLFLGHEG_00311 3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
GLFLGHEG_00312 2.3e-210 tcaB EGP Major facilitator Superfamily
GLFLGHEG_00313 3.4e-225 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GLFLGHEG_00314 5e-156 K Helix-turn-helix XRE-family like proteins
GLFLGHEG_00315 1.3e-123 ydhB S membrane transporter protein
GLFLGHEG_00316 2.9e-81 bltD 2.3.1.57 K FR47-like protein
GLFLGHEG_00317 4.1e-150 bltR K helix_turn_helix, mercury resistance
GLFLGHEG_00318 5.3e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GLFLGHEG_00319 2.7e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
GLFLGHEG_00320 4.4e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
GLFLGHEG_00321 4e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
GLFLGHEG_00322 1.6e-120 ydhC K FCD
GLFLGHEG_00323 3.7e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GLFLGHEG_00326 4.3e-266 pbpE V Beta-lactamase
GLFLGHEG_00328 1.2e-97 ydhK M Protein of unknown function (DUF1541)
GLFLGHEG_00329 1.2e-195 pbuE EGP Major facilitator Superfamily
GLFLGHEG_00330 5.1e-133 ydhQ K UTRA
GLFLGHEG_00331 2.6e-118 K FCD
GLFLGHEG_00332 1.7e-216 yeaN P COG2807 Cyanate permease
GLFLGHEG_00333 2.6e-49 sugE P Small Multidrug Resistance protein
GLFLGHEG_00334 2.3e-51 ykkC P Small Multidrug Resistance protein
GLFLGHEG_00335 5.3e-104 yvdT K Transcriptional regulator
GLFLGHEG_00336 3.5e-296 yveA E amino acid
GLFLGHEG_00337 3.2e-166 ydhU P Catalase
GLFLGHEG_00338 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
GLFLGHEG_00339 1.1e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
GLFLGHEG_00340 1.2e-253 iolT EGP Major facilitator Superfamily
GLFLGHEG_00343 3.4e-39 S COG NOG14552 non supervised orthologous group
GLFLGHEG_00344 7.8e-08
GLFLGHEG_00346 3.9e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GLFLGHEG_00347 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
GLFLGHEG_00348 7.1e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
GLFLGHEG_00349 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GLFLGHEG_00350 3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GLFLGHEG_00351 0.0 ydiF S ABC transporter
GLFLGHEG_00352 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GLFLGHEG_00353 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GLFLGHEG_00354 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GLFLGHEG_00355 3.9e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GLFLGHEG_00356 1.7e-27 ydiK S Domain of unknown function (DUF4305)
GLFLGHEG_00357 2.5e-127 ydiL S CAAX protease self-immunity
GLFLGHEG_00358 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GLFLGHEG_00359 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GLFLGHEG_00360 9.1e-14
GLFLGHEG_00361 7.2e-167 2.1.1.72 L DNA methylase
GLFLGHEG_00362 1.2e-145 3.1.21.5 KL Type III restriction enzyme res subunit
GLFLGHEG_00363 7.6e-151 ydjC S Abhydrolase domain containing 18
GLFLGHEG_00364 0.0 K NB-ARC domain
GLFLGHEG_00365 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
GLFLGHEG_00366 1.3e-249 gutA G MFS/sugar transport protein
GLFLGHEG_00367 2.6e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
GLFLGHEG_00368 2.3e-29 yjdJ S Domain of unknown function (DUF4306)
GLFLGHEG_00369 3.3e-113 pspA KT Phage shock protein A
GLFLGHEG_00370 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GLFLGHEG_00371 2.6e-119 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
GLFLGHEG_00372 3.1e-144 ydjI S virion core protein (lumpy skin disease virus)
GLFLGHEG_00373 0.0 yrhL I Acyltransferase family
GLFLGHEG_00374 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
GLFLGHEG_00375 2.2e-54 L COG2963 Transposase and inactivated derivatives
GLFLGHEG_00376 1.2e-147 rsiV S Protein of unknown function (DUF3298)
GLFLGHEG_00377 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
GLFLGHEG_00378 1.3e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
GLFLGHEG_00379 4.2e-62 ydjM M Lytic transglycolase
GLFLGHEG_00380 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
GLFLGHEG_00382 7.2e-35 ydjO S Cold-inducible protein YdjO
GLFLGHEG_00383 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
GLFLGHEG_00384 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
GLFLGHEG_00385 1.7e-151 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GLFLGHEG_00386 4.6e-177 yeaC S COG0714 MoxR-like ATPases
GLFLGHEG_00387 4.4e-214 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
GLFLGHEG_00388 0.0 yebA E COG1305 Transglutaminase-like enzymes
GLFLGHEG_00389 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GLFLGHEG_00390 1e-187 2.7.7.49 L DNA polymerase
GLFLGHEG_00391 3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
GLFLGHEG_00392 1.6e-247 S Domain of unknown function (DUF4179)
GLFLGHEG_00393 1.8e-208 pbuG S permease
GLFLGHEG_00394 1.5e-125 yebC M Membrane
GLFLGHEG_00396 3.4e-92 yebE S UPF0316 protein
GLFLGHEG_00397 6.1e-28 yebG S NETI protein
GLFLGHEG_00398 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GLFLGHEG_00399 2.3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GLFLGHEG_00400 3.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GLFLGHEG_00401 8.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GLFLGHEG_00402 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GLFLGHEG_00403 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GLFLGHEG_00404 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GLFLGHEG_00405 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GLFLGHEG_00406 6.6e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GLFLGHEG_00407 2.2e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GLFLGHEG_00408 4.6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GLFLGHEG_00409 2.4e-234 purD 6.3.4.13 F Belongs to the GARS family
GLFLGHEG_00410 1.2e-25 S Protein of unknown function (DUF2892)
GLFLGHEG_00411 0.0 yerA 3.5.4.2 F adenine deaminase
GLFLGHEG_00412 4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
GLFLGHEG_00413 2.4e-50 yerC S protein conserved in bacteria
GLFLGHEG_00414 2.3e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
GLFLGHEG_00415 9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GLFLGHEG_00416 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GLFLGHEG_00417 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GLFLGHEG_00418 2.1e-211 camS S COG4851 Protein involved in sex pheromone biosynthesis
GLFLGHEG_00419 1.1e-194 yerI S homoserine kinase type II (protein kinase fold)
GLFLGHEG_00420 4.3e-121 sapB S MgtC SapB transporter
GLFLGHEG_00421 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLFLGHEG_00422 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GLFLGHEG_00423 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GLFLGHEG_00424 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GLFLGHEG_00425 7.6e-152 yerO K Transcriptional regulator
GLFLGHEG_00426 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GLFLGHEG_00427 6.2e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GLFLGHEG_00428 4.1e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GLFLGHEG_00429 2e-14 L Recombinase zinc beta ribbon domain
GLFLGHEG_00430 0.0 K SIR2-like domain
GLFLGHEG_00431 1.5e-41 S Immunity protein 22
GLFLGHEG_00432 8.2e-76 S Protein of unknown function, DUF600
GLFLGHEG_00433 4e-57 S Protein of unknown function, DUF600
GLFLGHEG_00434 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
GLFLGHEG_00435 9.4e-127 yeeN K transcriptional regulatory protein
GLFLGHEG_00437 2.4e-108 aadK G Streptomycin adenylyltransferase
GLFLGHEG_00438 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
GLFLGHEG_00439 3.3e-45 cotJB S CotJB protein
GLFLGHEG_00440 8.9e-104 cotJC P Spore Coat
GLFLGHEG_00441 7.5e-97 yesJ K Acetyltransferase (GNAT) family
GLFLGHEG_00443 1.1e-121 yetF S membrane
GLFLGHEG_00444 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
GLFLGHEG_00445 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GLFLGHEG_00446 3.4e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GLFLGHEG_00447 7.6e-138 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
GLFLGHEG_00448 1.1e-110 cysT O COG0555 ABC-type sulfate transport system, permease component
GLFLGHEG_00449 1e-103 cysW P COG4208 ABC-type sulfate transport system, permease component
GLFLGHEG_00450 4.5e-133 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GLFLGHEG_00451 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
GLFLGHEG_00452 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
GLFLGHEG_00453 8.2e-106 yetJ S Belongs to the BI1 family
GLFLGHEG_00455 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
GLFLGHEG_00456 6.9e-209 yetM CH FAD binding domain
GLFLGHEG_00457 8.3e-196 yetN S Protein of unknown function (DUF3900)
GLFLGHEG_00458 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
GLFLGHEG_00460 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GLFLGHEG_00461 2.7e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
GLFLGHEG_00462 2.1e-171 yfnG 4.2.1.45 M dehydratase
GLFLGHEG_00463 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
GLFLGHEG_00464 1.9e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
GLFLGHEG_00465 1.6e-187 yfnD M Nucleotide-diphospho-sugar transferase
GLFLGHEG_00466 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
GLFLGHEG_00467 7.8e-247 yfnA E amino acid
GLFLGHEG_00468 5.9e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GLFLGHEG_00469 9.8e-115 yfmS NT chemotaxis protein
GLFLGHEG_00470 9.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
GLFLGHEG_00471 3.2e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GLFLGHEG_00472 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GLFLGHEG_00473 1.8e-69 yfmP K transcriptional
GLFLGHEG_00474 2.1e-208 yfmO EGP Major facilitator Superfamily
GLFLGHEG_00475 4.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GLFLGHEG_00476 1.1e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
GLFLGHEG_00477 3.7e-65 yfmK 2.3.1.128 K acetyltransferase
GLFLGHEG_00478 3.2e-189 yfmJ S N-terminal domain of oxidoreductase
GLFLGHEG_00479 2.9e-24 S Protein of unknown function (DUF3212)
GLFLGHEG_00480 1.3e-57 yflT S Heat induced stress protein YflT
GLFLGHEG_00481 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
GLFLGHEG_00482 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
GLFLGHEG_00483 8.3e-35 Q PFAM Collagen triple helix
GLFLGHEG_00484 3.5e-104 Q PFAM Collagen triple helix
GLFLGHEG_00485 4.6e-131 Q calcium- and calmodulin-responsive adenylate cyclase activity
GLFLGHEG_00486 8.9e-22 M1-820 Q Collagen triple helix repeat (20 copies)
GLFLGHEG_00487 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
GLFLGHEG_00488 1.1e-273 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GLFLGHEG_00489 1.8e-119 citT T response regulator
GLFLGHEG_00490 9.2e-178 yflP S Tripartite tricarboxylate transporter family receptor
GLFLGHEG_00491 3.8e-227 citM C Citrate transporter
GLFLGHEG_00492 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
GLFLGHEG_00493 2.7e-218 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GLFLGHEG_00494 1.7e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GLFLGHEG_00495 4.4e-123 yflK S protein conserved in bacteria
GLFLGHEG_00496 1.5e-14 yflJ S Protein of unknown function (DUF2639)
GLFLGHEG_00497 7e-19 yflI
GLFLGHEG_00498 3.1e-50 yflH S Protein of unknown function (DUF3243)
GLFLGHEG_00499 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
GLFLGHEG_00500 2.5e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
GLFLGHEG_00501 3.1e-72 yfmQ S Uncharacterised protein from bacillus cereus group
GLFLGHEG_00502 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GLFLGHEG_00503 7.8e-64 yhdN S Domain of unknown function (DUF1992)
GLFLGHEG_00504 5.4e-77 cotP O Belongs to the small heat shock protein (HSP20) family
GLFLGHEG_00505 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
GLFLGHEG_00506 1.5e-37 ydgB S Spore germination protein gerPA/gerPF
GLFLGHEG_00507 1.2e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GLFLGHEG_00508 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
GLFLGHEG_00509 2.6e-129 treR K transcriptional
GLFLGHEG_00510 1.2e-123 yfkO C nitroreductase
GLFLGHEG_00511 4.2e-125 yibF S YibE/F-like protein
GLFLGHEG_00512 4.1e-201 yibE S YibE/F-like protein
GLFLGHEG_00513 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
GLFLGHEG_00514 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
GLFLGHEG_00515 6.4e-185 K helix_turn _helix lactose operon repressor
GLFLGHEG_00516 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GLFLGHEG_00517 9.9e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GLFLGHEG_00518 4.3e-193 ydiM EGP Major facilitator Superfamily
GLFLGHEG_00519 2.7e-29 yfkK S Belongs to the UPF0435 family
GLFLGHEG_00520 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GLFLGHEG_00521 2e-52 yfkI S gas vesicle protein
GLFLGHEG_00522 6.8e-145 yihY S Belongs to the UPF0761 family
GLFLGHEG_00524 3.8e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
GLFLGHEG_00525 1.3e-185 cax P COG0387 Ca2 H antiporter
GLFLGHEG_00526 2.5e-144 yfkD S YfkD-like protein
GLFLGHEG_00527 1.2e-146 yfkC M Mechanosensitive ion channel
GLFLGHEG_00528 3e-220 yfkA S YfkB-like domain
GLFLGHEG_00529 4.9e-27 yfjT
GLFLGHEG_00530 4.5e-154 pdaA G deacetylase
GLFLGHEG_00531 1.5e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
GLFLGHEG_00532 3.9e-31
GLFLGHEG_00533 3.8e-184 corA P Mediates influx of magnesium ions
GLFLGHEG_00534 2e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GLFLGHEG_00535 5.6e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GLFLGHEG_00536 1.7e-50 S YfzA-like protein
GLFLGHEG_00538 4.6e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GLFLGHEG_00539 1.4e-92 yfjM S Psort location Cytoplasmic, score
GLFLGHEG_00540 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GLFLGHEG_00541 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GLFLGHEG_00542 2.6e-214 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GLFLGHEG_00543 5.4e-256 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GLFLGHEG_00544 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
GLFLGHEG_00545 4.2e-15 sspH S Belongs to the SspH family
GLFLGHEG_00546 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GLFLGHEG_00547 5.1e-139 glvR F Helix-turn-helix domain, rpiR family
GLFLGHEG_00548 2.4e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GLFLGHEG_00549 0.0 yfiB3 V ABC transporter
GLFLGHEG_00550 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
GLFLGHEG_00551 7e-63 mhqP S DoxX
GLFLGHEG_00552 2.6e-160 yfiE 1.13.11.2 S glyoxalase
GLFLGHEG_00553 3.8e-168 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GLFLGHEG_00554 1.7e-96 padR K transcriptional
GLFLGHEG_00555 4.6e-111 1.6.5.2 S NADPH-dependent FMN reductase
GLFLGHEG_00556 1.7e-183 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GLFLGHEG_00557 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
GLFLGHEG_00558 1.5e-45 yrdF K ribonuclease inhibitor
GLFLGHEG_00559 1.4e-98 yfiT S Belongs to the metal hydrolase YfiT family
GLFLGHEG_00560 2.3e-290 yfiU EGP Major facilitator Superfamily
GLFLGHEG_00561 5.6e-83 yfiV K transcriptional
GLFLGHEG_00562 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GLFLGHEG_00563 5.1e-167 yfhB 5.3.3.17 S PhzF family
GLFLGHEG_00564 7.4e-106 yfhC C nitroreductase
GLFLGHEG_00565 8e-25 yfhD S YfhD-like protein
GLFLGHEG_00567 2.6e-166 yfhF S nucleoside-diphosphate sugar epimerase
GLFLGHEG_00568 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
GLFLGHEG_00569 8.8e-53 yfhH S Protein of unknown function (DUF1811)
GLFLGHEG_00570 2.6e-206 yfhI EGP Major facilitator Superfamily
GLFLGHEG_00572 4e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
GLFLGHEG_00573 2.2e-44 yfhJ S WVELL protein
GLFLGHEG_00574 1.6e-94 batE T Bacterial SH3 domain homologues
GLFLGHEG_00575 2.6e-34 yfhL S SdpI/YhfL protein family
GLFLGHEG_00576 6.3e-170 yfhM S Alpha/beta hydrolase family
GLFLGHEG_00577 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GLFLGHEG_00578 0.0 yfhO S Bacterial membrane protein YfhO
GLFLGHEG_00579 1e-184 yfhP S membrane-bound metal-dependent
GLFLGHEG_00580 1.8e-209 mutY L A G-specific
GLFLGHEG_00581 8.2e-37 yfhS
GLFLGHEG_00582 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GLFLGHEG_00584 1.5e-37 ygaB S YgaB-like protein
GLFLGHEG_00585 2.2e-104 ygaC J Belongs to the UPF0374 family
GLFLGHEG_00586 4.2e-306 ygaD V ABC transporter
GLFLGHEG_00587 3.2e-179 ygaE S Membrane
GLFLGHEG_00588 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
GLFLGHEG_00589 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
GLFLGHEG_00590 1.8e-80 perR P Belongs to the Fur family
GLFLGHEG_00591 1.5e-56 ygzB S UPF0295 protein
GLFLGHEG_00592 3.7e-165 ygxA S Nucleotidyltransferase-like
GLFLGHEG_00593 3.4e-39 S COG NOG14552 non supervised orthologous group
GLFLGHEG_00598 7.8e-08
GLFLGHEG_00606 1.6e-08
GLFLGHEG_00610 1.6e-283 C Na+/H+ antiporter family
GLFLGHEG_00611 3e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
GLFLGHEG_00612 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GLFLGHEG_00613 5.3e-172 ygaK C Berberine and berberine like
GLFLGHEG_00614 8.7e-72 ygaK C Berberine and berberine like
GLFLGHEG_00616 5.4e-229 oppA5 E PFAM extracellular solute-binding protein family 5
GLFLGHEG_00617 5.4e-138 appB P Binding-protein-dependent transport system inner membrane component
GLFLGHEG_00618 2.4e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLFLGHEG_00619 3.7e-134 oppD3 P Belongs to the ABC transporter superfamily
GLFLGHEG_00620 7.6e-132 oppF3 E Belongs to the ABC transporter superfamily
GLFLGHEG_00621 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
GLFLGHEG_00622 2.2e-184 S Amidohydrolase
GLFLGHEG_00623 4.2e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
GLFLGHEG_00624 9.1e-181 ssuA M Sulfonate ABC transporter
GLFLGHEG_00625 3e-145 ssuC P ABC transporter (permease)
GLFLGHEG_00626 3.8e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
GLFLGHEG_00627 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GLFLGHEG_00628 3.3e-80 ygaO
GLFLGHEG_00630 1.9e-112 yhzB S B3/4 domain
GLFLGHEG_00631 1.9e-225 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GLFLGHEG_00632 5.5e-175 yhbB S Putative amidase domain
GLFLGHEG_00633 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GLFLGHEG_00634 1e-108 yhbD K Protein of unknown function (DUF4004)
GLFLGHEG_00635 2.8e-62 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
GLFLGHEG_00636 1.3e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
GLFLGHEG_00638 0.0 prkA T Ser protein kinase
GLFLGHEG_00639 2.7e-216 yhbH S Belongs to the UPF0229 family
GLFLGHEG_00640 4.6e-74 yhbI K DNA-binding transcription factor activity
GLFLGHEG_00641 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
GLFLGHEG_00642 8.4e-285 yhcA EGP Major facilitator Superfamily
GLFLGHEG_00643 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
GLFLGHEG_00644 3.8e-55 yhcC
GLFLGHEG_00645 9.6e-53
GLFLGHEG_00646 2.5e-62 yhcF K Transcriptional regulator
GLFLGHEG_00647 1e-125 yhcG V ABC transporter, ATP-binding protein
GLFLGHEG_00648 4.1e-167 yhcH V ABC transporter, ATP-binding protein
GLFLGHEG_00649 1.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GLFLGHEG_00650 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
GLFLGHEG_00651 4.2e-147 metQ M Belongs to the nlpA lipoprotein family
GLFLGHEG_00652 6.6e-193 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
GLFLGHEG_00653 3.5e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GLFLGHEG_00654 2e-55 yhcM
GLFLGHEG_00655 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GLFLGHEG_00656 3.3e-161 yhcP
GLFLGHEG_00657 5.8e-115 yhcQ M Spore coat protein
GLFLGHEG_00658 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
GLFLGHEG_00659 4.8e-108 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
GLFLGHEG_00660 2.8e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GLFLGHEG_00661 2.9e-69 yhcU S Family of unknown function (DUF5365)
GLFLGHEG_00662 7.6e-68 yhcV S COG0517 FOG CBS domain
GLFLGHEG_00663 5.5e-124 yhcW 5.4.2.6 S hydrolase
GLFLGHEG_00664 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GLFLGHEG_00665 1.9e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GLFLGHEG_00666 1.5e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GLFLGHEG_00667 4.5e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
GLFLGHEG_00668 7e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GLFLGHEG_00669 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GLFLGHEG_00670 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
GLFLGHEG_00671 1.7e-207 yhcY 2.7.13.3 T Histidine kinase
GLFLGHEG_00672 1e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GLFLGHEG_00673 8.8e-90 azr 1.7.1.6 S NADPH-dependent FMN reductase
GLFLGHEG_00674 2.5e-39 yhdB S YhdB-like protein
GLFLGHEG_00675 4e-53 yhdC S Protein of unknown function (DUF3889)
GLFLGHEG_00676 2.6e-216 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
GLFLGHEG_00677 1.9e-74 nsrR K Transcriptional regulator
GLFLGHEG_00678 4.5e-256 ygxB M Conserved TM helix
GLFLGHEG_00679 1.2e-271 ycgB S Stage V sporulation protein R
GLFLGHEG_00680 8.9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
GLFLGHEG_00681 4.8e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
GLFLGHEG_00682 5.8e-163 citR K Transcriptional regulator
GLFLGHEG_00683 4.9e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
GLFLGHEG_00684 1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GLFLGHEG_00685 3e-11 yhdG E amino acid
GLFLGHEG_00686 8e-191 yhdG E amino acid
GLFLGHEG_00687 2.6e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GLFLGHEG_00688 8.1e-45 yhdK S Sigma-M inhibitor protein
GLFLGHEG_00689 6.6e-201 yhdL S Sigma factor regulator N-terminal
GLFLGHEG_00690 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
GLFLGHEG_00691 1.3e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GLFLGHEG_00692 2.8e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
GLFLGHEG_00693 4.3e-71 cueR K transcriptional
GLFLGHEG_00694 7.7e-227 yhdR 2.6.1.1 E Aminotransferase
GLFLGHEG_00695 2.3e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GLFLGHEG_00696 1.1e-256 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
GLFLGHEG_00697 2.5e-51 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GLFLGHEG_00698 2e-62 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GLFLGHEG_00699 2e-129 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GLFLGHEG_00701 3.5e-205 yhdY M Mechanosensitive ion channel
GLFLGHEG_00702 6.5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GLFLGHEG_00703 1e-156 yheN G deacetylase
GLFLGHEG_00704 4.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
GLFLGHEG_00705 4.6e-88 pksA K Transcriptional regulator
GLFLGHEG_00706 1.2e-94 ymcC S Membrane
GLFLGHEG_00707 2.1e-85 T universal stress protein
GLFLGHEG_00709 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
GLFLGHEG_00710 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
GLFLGHEG_00711 7.4e-112 yheG GM NAD(P)H-binding
GLFLGHEG_00713 2.9e-28 sspB S spore protein
GLFLGHEG_00714 1.7e-36 yheE S Family of unknown function (DUF5342)
GLFLGHEG_00715 7.2e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
GLFLGHEG_00716 4.8e-215 yheC HJ YheC/D like ATP-grasp
GLFLGHEG_00717 7.2e-206 yheB S Belongs to the UPF0754 family
GLFLGHEG_00718 4.4e-53 yheA S Belongs to the UPF0342 family
GLFLGHEG_00719 1.3e-202 yhaZ L DNA alkylation repair enzyme
GLFLGHEG_00720 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
GLFLGHEG_00721 9.3e-294 hemZ H coproporphyrinogen III oxidase
GLFLGHEG_00722 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
GLFLGHEG_00723 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
GLFLGHEG_00724 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
GLFLGHEG_00726 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
GLFLGHEG_00727 2.8e-14 S YhzD-like protein
GLFLGHEG_00728 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
GLFLGHEG_00729 1e-205 yhaP CP COG1668 ABC-type Na efflux pump, permease component
GLFLGHEG_00730 7.9e-235 yhaO L DNA repair exonuclease
GLFLGHEG_00731 0.0 yhaN L AAA domain
GLFLGHEG_00732 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
GLFLGHEG_00733 1.1e-31 yhaL S Sporulation protein YhaL
GLFLGHEG_00734 3.3e-123 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GLFLGHEG_00735 7e-95 yhaK S Putative zincin peptidase
GLFLGHEG_00736 9.9e-55 yhaI S Protein of unknown function (DUF1878)
GLFLGHEG_00737 8.6e-113 hpr K Negative regulator of protease production and sporulation
GLFLGHEG_00738 6.2e-39 yhaH S YtxH-like protein
GLFLGHEG_00739 2e-17
GLFLGHEG_00740 2.9e-77 trpP S Tryptophan transporter TrpP
GLFLGHEG_00741 1.2e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GLFLGHEG_00742 5.2e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GLFLGHEG_00743 1.1e-135 ecsA V transporter (ATP-binding protein)
GLFLGHEG_00744 8.5e-221 ecsB U ABC transporter
GLFLGHEG_00745 7.3e-124 ecsC S EcsC protein family
GLFLGHEG_00746 2.1e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GLFLGHEG_00747 2.6e-242 yhfA C membrane
GLFLGHEG_00748 1.9e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
GLFLGHEG_00749 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GLFLGHEG_00750 6.2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GLFLGHEG_00751 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GLFLGHEG_00752 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GLFLGHEG_00753 3.2e-101 yhgD K Transcriptional regulator
GLFLGHEG_00754 3.2e-277 yhgE S YhgE Pip N-terminal domain protein
GLFLGHEG_00755 7.4e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GLFLGHEG_00757 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
GLFLGHEG_00758 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GLFLGHEG_00759 7.9e-11 yhfH S YhfH-like protein
GLFLGHEG_00760 9.9e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
GLFLGHEG_00761 3.5e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
GLFLGHEG_00762 1.3e-111 yhfK GM NmrA-like family
GLFLGHEG_00763 6.4e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
GLFLGHEG_00764 1.3e-64 yhfM
GLFLGHEG_00765 5.1e-237 yhfN 3.4.24.84 O Peptidase M48
GLFLGHEG_00766 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
GLFLGHEG_00767 3.8e-154 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
GLFLGHEG_00768 1.7e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
GLFLGHEG_00769 5.5e-203 vraB 2.3.1.9 I Belongs to the thiolase family
GLFLGHEG_00770 7.3e-280 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
GLFLGHEG_00771 1e-88 bioY S BioY family
GLFLGHEG_00772 9.1e-197 hemAT NT chemotaxis protein
GLFLGHEG_00773 1.1e-297 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
GLFLGHEG_00774 8.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GLFLGHEG_00775 1.4e-31 yhzC S IDEAL
GLFLGHEG_00776 1.9e-109 comK K Competence transcription factor
GLFLGHEG_00777 5.2e-65 frataxin S Domain of unknown function (DU1801)
GLFLGHEG_00778 2.6e-64 frataxin S Domain of unknown function (DU1801)
GLFLGHEG_00779 8.2e-93 mepB S MepB protein
GLFLGHEG_00780 1.2e-126 yrpD S Domain of unknown function, YrpD
GLFLGHEG_00781 1.6e-42 yhjA S Excalibur calcium-binding domain
GLFLGHEG_00782 3.3e-47 S Belongs to the UPF0145 family
GLFLGHEG_00783 8.6e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLFLGHEG_00784 1.4e-27 yhjC S Protein of unknown function (DUF3311)
GLFLGHEG_00785 1.1e-59 yhjD
GLFLGHEG_00786 1.4e-110 yhjE S SNARE associated Golgi protein
GLFLGHEG_00787 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
GLFLGHEG_00788 1.3e-265 yhjG CH FAD binding domain
GLFLGHEG_00789 1.7e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
GLFLGHEG_00790 4e-188 abrB S membrane
GLFLGHEG_00791 5.6e-209 blt EGP Major facilitator Superfamily
GLFLGHEG_00792 4.5e-109 K QacR-like protein, C-terminal region
GLFLGHEG_00793 9.7e-94 yhjR S Rubrerythrin
GLFLGHEG_00794 6.7e-125 ydfS S Protein of unknown function (DUF421)
GLFLGHEG_00795 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
GLFLGHEG_00796 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GLFLGHEG_00797 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GLFLGHEG_00798 0.0 sbcC L COG0419 ATPase involved in DNA repair
GLFLGHEG_00799 5e-50 yisB V COG1403 Restriction endonuclease
GLFLGHEG_00800 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
GLFLGHEG_00801 8.1e-64 gerPE S Spore germination protein GerPE
GLFLGHEG_00802 3.1e-23 gerPD S Spore germination protein
GLFLGHEG_00803 1.4e-62 gerPC S Spore germination protein
GLFLGHEG_00804 6.2e-35 gerPB S cell differentiation
GLFLGHEG_00805 8.4e-34 gerPA S Spore germination protein
GLFLGHEG_00806 5e-07 yisI S Spo0E like sporulation regulatory protein
GLFLGHEG_00807 7.8e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
GLFLGHEG_00808 1.1e-59 yisL S UPF0344 protein
GLFLGHEG_00809 3.8e-96 yisN S Protein of unknown function (DUF2777)
GLFLGHEG_00810 0.0 asnO 6.3.5.4 E Asparagine synthase
GLFLGHEG_00811 5.3e-133 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
GLFLGHEG_00812 3.3e-245 yisQ V Mate efflux family protein
GLFLGHEG_00813 5e-159 yisR K Transcriptional regulator
GLFLGHEG_00814 3.7e-90 yisT S DinB family
GLFLGHEG_00815 1.1e-70 mcbG S Pentapeptide repeats (9 copies)
GLFLGHEG_00816 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
GLFLGHEG_00817 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
GLFLGHEG_00818 6.6e-55 yajQ S Belongs to the UPF0234 family
GLFLGHEG_00819 9e-161 cvfB S protein conserved in bacteria
GLFLGHEG_00820 3.7e-174 yufN S ABC transporter substrate-binding protein PnrA-like
GLFLGHEG_00821 2.7e-230 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
GLFLGHEG_00822 5.8e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
GLFLGHEG_00824 3.6e-48 yitS S protein conserved in bacteria
GLFLGHEG_00825 4.5e-100 yitS S protein conserved in bacteria
GLFLGHEG_00826 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
GLFLGHEG_00827 2.9e-81 ipi S Intracellular proteinase inhibitor
GLFLGHEG_00828 4.4e-26 S Protein of unknown function (DUF3813)
GLFLGHEG_00829 3.5e-07
GLFLGHEG_00830 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GLFLGHEG_00831 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
GLFLGHEG_00832 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
GLFLGHEG_00833 5.9e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
GLFLGHEG_00834 2.1e-271 yitY C D-arabinono-1,4-lactone oxidase
GLFLGHEG_00835 4.1e-90 norB G Major Facilitator Superfamily
GLFLGHEG_00836 4.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GLFLGHEG_00837 7.9e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GLFLGHEG_00838 1.5e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
GLFLGHEG_00839 3.1e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
GLFLGHEG_00840 8.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GLFLGHEG_00841 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
GLFLGHEG_00842 4.6e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GLFLGHEG_00843 1.2e-27 yjzC S YjzC-like protein
GLFLGHEG_00844 3.3e-23 yjzD S Protein of unknown function (DUF2929)
GLFLGHEG_00845 4.6e-137 yjaU I carboxylic ester hydrolase activity
GLFLGHEG_00846 1.5e-106 yjaV
GLFLGHEG_00847 1.9e-166 med S Transcriptional activator protein med
GLFLGHEG_00848 1.9e-26 comZ S ComZ
GLFLGHEG_00849 5.9e-32 yjzB
GLFLGHEG_00850 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GLFLGHEG_00851 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GLFLGHEG_00852 3.6e-148 yjaZ O Zn-dependent protease
GLFLGHEG_00853 3.3e-183 appD P Belongs to the ABC transporter superfamily
GLFLGHEG_00854 5.9e-188 appF E Belongs to the ABC transporter superfamily
GLFLGHEG_00855 3.1e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
GLFLGHEG_00856 7e-170 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLFLGHEG_00857 6.1e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLFLGHEG_00858 3.8e-86 2.1.1.265 H Tellurite resistance protein TehB
GLFLGHEG_00859 4.6e-140 EGP Transmembrane secretion effector
GLFLGHEG_00860 5.5e-146 yjbA S Belongs to the UPF0736 family
GLFLGHEG_00861 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
GLFLGHEG_00862 0.0 oppA E ABC transporter substrate-binding protein
GLFLGHEG_00863 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLFLGHEG_00864 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLFLGHEG_00865 2.7e-202 oppD P Belongs to the ABC transporter superfamily
GLFLGHEG_00866 2.5e-172 oppF E Belongs to the ABC transporter superfamily
GLFLGHEG_00867 1.2e-227 S Putative glycosyl hydrolase domain
GLFLGHEG_00868 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GLFLGHEG_00869 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GLFLGHEG_00870 1.6e-109 yjbE P Integral membrane protein TerC family
GLFLGHEG_00871 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GLFLGHEG_00872 1.1e-220 yjbF S Competence protein
GLFLGHEG_00873 0.0 pepF E oligoendopeptidase F
GLFLGHEG_00874 5.8e-19
GLFLGHEG_00875 8.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
GLFLGHEG_00876 5.3e-71 yjbI S Bacterial-like globin
GLFLGHEG_00877 3.8e-117 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GLFLGHEG_00878 1.2e-100 yjbK S protein conserved in bacteria
GLFLGHEG_00879 6e-61 yjbL S Belongs to the UPF0738 family
GLFLGHEG_00880 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
GLFLGHEG_00881 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GLFLGHEG_00882 1.2e-163 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GLFLGHEG_00883 4e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
GLFLGHEG_00884 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GLFLGHEG_00885 2.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GLFLGHEG_00886 3.5e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
GLFLGHEG_00887 5.9e-213 thiO 1.4.3.19 E Glycine oxidase
GLFLGHEG_00888 1.4e-30 thiS H Thiamine biosynthesis
GLFLGHEG_00889 3.8e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
GLFLGHEG_00890 1.8e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GLFLGHEG_00891 7.1e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GLFLGHEG_00892 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
GLFLGHEG_00893 3e-89 yjbX S Spore coat protein
GLFLGHEG_00894 6.9e-80 cotZ S Spore coat protein
GLFLGHEG_00895 1.6e-90 cotY S Spore coat protein Z
GLFLGHEG_00896 4.4e-75 cotX S Spore Coat Protein X and V domain
GLFLGHEG_00897 1.1e-23 cotW
GLFLGHEG_00898 4.2e-57 cotV S Spore Coat Protein X and V domain
GLFLGHEG_00899 2.5e-56 yjcA S Protein of unknown function (DUF1360)
GLFLGHEG_00903 3.8e-38 spoVIF S Stage VI sporulation protein F
GLFLGHEG_00904 0.0 yjcD 3.6.4.12 L DNA helicase
GLFLGHEG_00905 4.6e-36
GLFLGHEG_00906 5.3e-141 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
GLFLGHEG_00907 1.5e-124 S ABC-2 type transporter
GLFLGHEG_00908 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
GLFLGHEG_00909 9.4e-36 K SpoVT / AbrB like domain
GLFLGHEG_00911 5e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GLFLGHEG_00912 1.2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
GLFLGHEG_00913 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
GLFLGHEG_00914 1.3e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GLFLGHEG_00915 2.6e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GLFLGHEG_00917 4.5e-177 L Belongs to the 'phage' integrase family
GLFLGHEG_00918 1.3e-48 xkdA E IrrE N-terminal-like domain
GLFLGHEG_00919 1.6e-07 S Short C-terminal domain
GLFLGHEG_00920 1.2e-45 xre K Helix-turn-helix XRE-family like proteins
GLFLGHEG_00921 1.2e-19 K Helix-turn-helix XRE-family like proteins
GLFLGHEG_00922 3.4e-15 S Helix-turn-helix domain
GLFLGHEG_00923 3.2e-85
GLFLGHEG_00927 1.2e-99
GLFLGHEG_00928 3.8e-68 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
GLFLGHEG_00930 1.2e-73 3.1.3.16 L DnaD domain protein
GLFLGHEG_00931 5.5e-122 xkdC L IstB-like ATP binding protein
GLFLGHEG_00933 3.8e-59 rusA L Endodeoxyribonuclease RusA
GLFLGHEG_00935 5e-17 yqaO S Phage-like element PBSX protein XtrA
GLFLGHEG_00941 1.7e-66 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GLFLGHEG_00942 6e-13 K Transcriptional regulator
GLFLGHEG_00943 5e-41 S Protein of unknown function (DUF2971)
GLFLGHEG_00945 1.4e-75 yqaS L DNA packaging
GLFLGHEG_00946 1.4e-178 S Pfam:Terminase_3C
GLFLGHEG_00947 3.5e-120 S Phage portal protein, SPP1 Gp6-like
GLFLGHEG_00948 2.8e-91 S Phage Mu protein F like protein
GLFLGHEG_00949 2.1e-43 S Phage minor structural protein GP20
GLFLGHEG_00950 2.9e-54 gpG
GLFLGHEG_00953 2.7e-27 S Phage gp6-like head-tail connector protein
GLFLGHEG_00954 1.6e-28 S Phage head-tail joining protein
GLFLGHEG_00955 4.7e-38 S Bacteriophage HK97-gp10, putative tail-component
GLFLGHEG_00956 7.7e-30 S Protein of unknown function (DUF3168)
GLFLGHEG_00957 7.4e-33 S Phage tail tube protein
GLFLGHEG_00958 3.3e-25 S Phage tail assembly chaperone protein, TAC
GLFLGHEG_00959 1.6e-130
GLFLGHEG_00960 1e-46
GLFLGHEG_00961 1.1e-225 S peptidoglycan catabolic process
GLFLGHEG_00966 7.1e-58 S Pfam:Phage_holin_4_1
GLFLGHEG_00967 1.3e-103 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GLFLGHEG_00969 8.1e-26
GLFLGHEG_00970 1.3e-30 S SMI1-KNR4 cell-wall
GLFLGHEG_00971 1.9e-192 M nucleic acid phosphodiester bond hydrolysis
GLFLGHEG_00975 2.5e-64
GLFLGHEG_00976 2.1e-31 L Belongs to the 'phage' integrase family
GLFLGHEG_00977 8.7e-31
GLFLGHEG_00978 1.2e-83
GLFLGHEG_00979 1.5e-22
GLFLGHEG_00980 3.5e-258 yobL S Bacterial EndoU nuclease
GLFLGHEG_00983 5.9e-59 E Glyoxalase-like domain
GLFLGHEG_00984 2.9e-165 bla 3.5.2.6 V beta-lactamase
GLFLGHEG_00985 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
GLFLGHEG_00986 1.3e-249 yfjF EGP Belongs to the major facilitator superfamily
GLFLGHEG_00987 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
GLFLGHEG_00988 3.5e-221 ganA 3.2.1.89 G arabinogalactan
GLFLGHEG_00989 6.2e-290 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GLFLGHEG_00990 6.3e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GLFLGHEG_00991 4.9e-218 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GLFLGHEG_00992 0.0 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GLFLGHEG_00993 2.2e-48 lacF 2.7.1.207 G phosphotransferase system
GLFLGHEG_00994 7.6e-282 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
GLFLGHEG_00995 5.7e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
GLFLGHEG_00996 4.9e-125 5.4.2.6 S Haloacid dehalogenase-like hydrolase
GLFLGHEG_00997 3.5e-34
GLFLGHEG_00998 2.2e-51 K helix_turn_helix multiple antibiotic resistance protein
GLFLGHEG_00999 8.1e-106 yhiD S MgtC SapB transporter
GLFLGHEG_01000 7.5e-22 yjfB S Putative motility protein
GLFLGHEG_01001 6.3e-47 T PhoQ Sensor
GLFLGHEG_01002 5e-99 yjgB S Domain of unknown function (DUF4309)
GLFLGHEG_01003 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
GLFLGHEG_01004 4.3e-92 yjgD S Protein of unknown function (DUF1641)
GLFLGHEG_01005 7.2e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
GLFLGHEG_01006 3.4e-222 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GLFLGHEG_01007 6.8e-29
GLFLGHEG_01008 2.8e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
GLFLGHEG_01009 3e-123 ybbM S transport system, permease component
GLFLGHEG_01010 1.7e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
GLFLGHEG_01011 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
GLFLGHEG_01012 1.8e-92 yjlB S Cupin domain
GLFLGHEG_01013 9.1e-66 yjlC S Protein of unknown function (DUF1641)
GLFLGHEG_01014 3.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
GLFLGHEG_01015 9.6e-277 uxaC 5.3.1.12 G glucuronate isomerase
GLFLGHEG_01016 6.6e-254 yjmB G symporter YjmB
GLFLGHEG_01017 3.4e-183 exuR K transcriptional
GLFLGHEG_01018 1.5e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
GLFLGHEG_01019 3.8e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
GLFLGHEG_01020 1.5e-130 MA20_18170 S membrane transporter protein
GLFLGHEG_01021 6.2e-79 yjoA S DinB family
GLFLGHEG_01022 4.9e-215 S response regulator aspartate phosphatase
GLFLGHEG_01024 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GLFLGHEG_01025 4.7e-61 yjqA S Bacterial PH domain
GLFLGHEG_01026 2.1e-111 yjqB S phage-related replication protein
GLFLGHEG_01028 1.3e-110 xkdA E IrrE N-terminal-like domain
GLFLGHEG_01029 1.2e-55 xre K Helix-turn-helix XRE-family like proteins
GLFLGHEG_01031 6.5e-153 xkdC L Bacterial dnaA protein
GLFLGHEG_01034 2e-10 yqaO S Phage-like element PBSX protein XtrA
GLFLGHEG_01035 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GLFLGHEG_01036 1.2e-109 xtmA L phage terminase small subunit
GLFLGHEG_01037 2.7e-209 xtmB S phage terminase, large subunit
GLFLGHEG_01038 4.6e-242 yqbA S portal protein
GLFLGHEG_01039 5.7e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
GLFLGHEG_01040 1.7e-157 xkdG S Phage capsid family
GLFLGHEG_01041 2.8e-45 yqbG S Protein of unknown function (DUF3199)
GLFLGHEG_01042 5.5e-43 yqbH S Domain of unknown function (DUF3599)
GLFLGHEG_01043 1.4e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
GLFLGHEG_01044 2.2e-57 xkdJ
GLFLGHEG_01045 3.1e-14
GLFLGHEG_01046 2.2e-225 xkdK S Phage tail sheath C-terminal domain
GLFLGHEG_01047 2e-74 xkdM S Phage tail tube protein
GLFLGHEG_01048 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
GLFLGHEG_01049 3.4e-19
GLFLGHEG_01050 7.6e-199 xkdO L Transglycosylase SLT domain
GLFLGHEG_01051 8.7e-111 xkdP S Lysin motif
GLFLGHEG_01052 1.4e-160 xkdQ 3.2.1.96 G NLP P60 protein
GLFLGHEG_01053 7.2e-32 xkdR S Protein of unknown function (DUF2577)
GLFLGHEG_01054 7.2e-58 xkdS S Protein of unknown function (DUF2634)
GLFLGHEG_01055 4.3e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
GLFLGHEG_01056 5.5e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
GLFLGHEG_01057 1.2e-26
GLFLGHEG_01058 3.4e-92
GLFLGHEG_01060 1.9e-29 xkdX
GLFLGHEG_01061 9.6e-138 xepA
GLFLGHEG_01062 8.7e-38 xhlA S Haemolysin XhlA
GLFLGHEG_01063 1.3e-38 xhlB S SPP1 phage holin
GLFLGHEG_01064 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GLFLGHEG_01065 8.7e-23 spoIISB S Stage II sporulation protein SB
GLFLGHEG_01066 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
GLFLGHEG_01067 7.5e-175 pit P phosphate transporter
GLFLGHEG_01068 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
GLFLGHEG_01069 5.2e-243 steT E amino acid
GLFLGHEG_01070 5e-184 mhqA E COG0346 Lactoylglutathione lyase and related lyases
GLFLGHEG_01071 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GLFLGHEG_01072 1.4e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GLFLGHEG_01074 7.3e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GLFLGHEG_01075 2.5e-286 yubD P Major Facilitator Superfamily
GLFLGHEG_01077 6.5e-156 dppA E D-aminopeptidase
GLFLGHEG_01078 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLFLGHEG_01079 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GLFLGHEG_01080 1.3e-190 dppD P Belongs to the ABC transporter superfamily
GLFLGHEG_01081 0.0 dppE E ABC transporter substrate-binding protein
GLFLGHEG_01082 6.4e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
GLFLGHEG_01083 1.6e-157 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
GLFLGHEG_01084 3.2e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GLFLGHEG_01085 1.2e-182 ykfD E Belongs to the ABC transporter superfamily
GLFLGHEG_01086 2.3e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
GLFLGHEG_01087 3.2e-158 ykgA E Amidinotransferase
GLFLGHEG_01088 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
GLFLGHEG_01089 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GLFLGHEG_01090 9.4e-53 ykkC P Multidrug resistance protein
GLFLGHEG_01091 3.4e-49 ykkD P Multidrug resistance protein
GLFLGHEG_01092 1.5e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
GLFLGHEG_01093 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GLFLGHEG_01094 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GLFLGHEG_01095 1.3e-70 ohrA O Organic hydroperoxide resistance protein
GLFLGHEG_01096 2.2e-85 ohrR K COG1846 Transcriptional regulators
GLFLGHEG_01097 4.2e-71 ohrB O Organic hydroperoxide resistance protein
GLFLGHEG_01098 2.2e-55 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GLFLGHEG_01100 1.1e-214 M Glycosyl transferase family 2
GLFLGHEG_01101 3e-132 M PFAM Collagen triple helix repeat (20 copies)
GLFLGHEG_01102 9.4e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
GLFLGHEG_01103 4e-119 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
GLFLGHEG_01104 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GLFLGHEG_01105 8.6e-176 isp O Belongs to the peptidase S8 family
GLFLGHEG_01106 1.2e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GLFLGHEG_01107 2.1e-132 ykoC P Cobalt transport protein
GLFLGHEG_01108 4.8e-304 P ABC transporter, ATP-binding protein
GLFLGHEG_01109 1.7e-97 ykoE S ABC-type cobalt transport system, permease component
GLFLGHEG_01110 3.9e-245 ydhD M Glycosyl hydrolase
GLFLGHEG_01112 2.2e-238 mgtE P Acts as a magnesium transporter
GLFLGHEG_01113 5.4e-53 tnrA K transcriptional
GLFLGHEG_01114 1.9e-16
GLFLGHEG_01115 3.1e-26 ykoL
GLFLGHEG_01116 5e-81 ykoM K transcriptional
GLFLGHEG_01117 2.2e-99 ykoP G polysaccharide deacetylase
GLFLGHEG_01118 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
GLFLGHEG_01119 9.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GLFLGHEG_01120 4.1e-101 ykoX S membrane-associated protein
GLFLGHEG_01121 1.2e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
GLFLGHEG_01122 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GLFLGHEG_01123 3.1e-119 rsgI S Anti-sigma factor N-terminus
GLFLGHEG_01124 2.5e-26 sspD S small acid-soluble spore protein
GLFLGHEG_01125 7.8e-126 ykrK S Domain of unknown function (DUF1836)
GLFLGHEG_01126 4.1e-156 htpX O Belongs to the peptidase M48B family
GLFLGHEG_01127 1.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
GLFLGHEG_01128 7.2e-113 ydfR S Protein of unknown function (DUF421)
GLFLGHEG_01129 2.5e-22 ykzE
GLFLGHEG_01130 2e-191 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
GLFLGHEG_01131 0.0 kinE 2.7.13.3 T Histidine kinase
GLFLGHEG_01132 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GLFLGHEG_01134 5.3e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GLFLGHEG_01135 2.5e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GLFLGHEG_01136 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GLFLGHEG_01137 8.3e-229 mtnE 2.6.1.83 E Aminotransferase
GLFLGHEG_01138 6.1e-227 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
GLFLGHEG_01139 4.4e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GLFLGHEG_01140 2.2e-116 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
GLFLGHEG_01141 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GLFLGHEG_01142 3.4e-10 S Spo0E like sporulation regulatory protein
GLFLGHEG_01143 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
GLFLGHEG_01144 1.5e-77 ykvE K transcriptional
GLFLGHEG_01145 2.7e-127 motB N Flagellar motor protein
GLFLGHEG_01146 1.1e-136 motA N flagellar motor
GLFLGHEG_01147 0.0 clpE O Belongs to the ClpA ClpB family
GLFLGHEG_01148 9.2e-184 ykvI S membrane
GLFLGHEG_01149 1.5e-187
GLFLGHEG_01150 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GLFLGHEG_01151 1.3e-78 queD 4.1.2.50, 4.2.3.12 H synthase
GLFLGHEG_01152 1.1e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GLFLGHEG_01153 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GLFLGHEG_01154 5.1e-60 ykvN K Transcriptional regulator
GLFLGHEG_01155 7e-133 IQ Enoyl-(Acyl carrier protein) reductase
GLFLGHEG_01156 1.1e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GLFLGHEG_01157 7.8e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
GLFLGHEG_01158 1.3e-34 3.5.1.104 M LysM domain
GLFLGHEG_01159 3.4e-161 G Glycosyl hydrolases family 18
GLFLGHEG_01160 1.3e-44 ykvR S Protein of unknown function (DUF3219)
GLFLGHEG_01161 7.8e-25 ykvS S protein conserved in bacteria
GLFLGHEG_01162 2.3e-27
GLFLGHEG_01163 2.4e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
GLFLGHEG_01164 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GLFLGHEG_01165 2.9e-87 stoA CO thiol-disulfide
GLFLGHEG_01166 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
GLFLGHEG_01167 7.4e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
GLFLGHEG_01169 7.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
GLFLGHEG_01170 5.1e-156 glcT K antiterminator
GLFLGHEG_01171 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GLFLGHEG_01172 2.1e-39 ptsH G phosphocarrier protein HPr
GLFLGHEG_01173 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GLFLGHEG_01174 6.1e-38 splA S Transcriptional regulator
GLFLGHEG_01175 9.5e-189 splB 4.1.99.14 L Spore photoproduct lyase
GLFLGHEG_01176 1.2e-264 mcpC NT chemotaxis protein
GLFLGHEG_01177 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
GLFLGHEG_01178 9.8e-114 ykwD J protein with SCP PR1 domains
GLFLGHEG_01179 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
GLFLGHEG_01180 2.2e-289 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
GLFLGHEG_01181 3.9e-215 patA 2.6.1.1 E Aminotransferase
GLFLGHEG_01182 2.3e-09
GLFLGHEG_01183 1.8e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
GLFLGHEG_01184 1.4e-83 ykyB S YkyB-like protein
GLFLGHEG_01185 3e-240 ykuC EGP Major facilitator Superfamily
GLFLGHEG_01186 1.2e-88 ykuD S protein conserved in bacteria
GLFLGHEG_01187 8.9e-156 ykuE S Metallophosphoesterase
GLFLGHEG_01188 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GLFLGHEG_01190 1.5e-233 ykuI T Diguanylate phosphodiesterase
GLFLGHEG_01191 3.9e-37 ykuJ S protein conserved in bacteria
GLFLGHEG_01192 1.4e-92 ykuK S Ribonuclease H-like
GLFLGHEG_01193 2.5e-26 ykzF S Antirepressor AbbA
GLFLGHEG_01194 1e-75 ykuL S CBS domain
GLFLGHEG_01195 6e-168 ccpC K Transcriptional regulator
GLFLGHEG_01196 3e-89 fld C Flavodoxin
GLFLGHEG_01197 2.9e-170 ykuO
GLFLGHEG_01198 2.5e-80 fld C Flavodoxin
GLFLGHEG_01199 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GLFLGHEG_01200 3.8e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GLFLGHEG_01201 4.8e-38 ykuS S Belongs to the UPF0180 family
GLFLGHEG_01202 5.8e-141 ykuT M Mechanosensitive ion channel
GLFLGHEG_01203 1.1e-80 ykuV CO thiol-disulfide
GLFLGHEG_01204 4.5e-98 rok K Repressor of ComK
GLFLGHEG_01205 1.1e-162 yknT
GLFLGHEG_01206 4.1e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GLFLGHEG_01207 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GLFLGHEG_01208 1.3e-243 moeA 2.10.1.1 H molybdopterin
GLFLGHEG_01209 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
GLFLGHEG_01210 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
GLFLGHEG_01211 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GLFLGHEG_01212 1.4e-103 yknW S Yip1 domain
GLFLGHEG_01213 8.9e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GLFLGHEG_01214 6.1e-123 macB V ABC transporter, ATP-binding protein
GLFLGHEG_01215 2.7e-211 yknZ V ABC transporter (permease)
GLFLGHEG_01216 1.1e-133 fruR K Transcriptional regulator
GLFLGHEG_01217 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
GLFLGHEG_01218 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
GLFLGHEG_01219 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
GLFLGHEG_01220 1.5e-37 ykoA
GLFLGHEG_01221 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GLFLGHEG_01222 1.3e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GLFLGHEG_01223 5e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
GLFLGHEG_01224 5.5e-12 S Uncharacterized protein YkpC
GLFLGHEG_01225 6.9e-184 mreB D Rod-share determining protein MreBH
GLFLGHEG_01226 2.1e-45 abrB K of stationary sporulation gene expression
GLFLGHEG_01227 3.1e-245 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
GLFLGHEG_01228 9.1e-150 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
GLFLGHEG_01229 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
GLFLGHEG_01230 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GLFLGHEG_01231 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GLFLGHEG_01232 8.2e-31 ykzG S Belongs to the UPF0356 family
GLFLGHEG_01233 3.9e-147 ykrA S hydrolases of the HAD superfamily
GLFLGHEG_01234 5.8e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GLFLGHEG_01236 5.9e-104 recN L Putative cell-wall binding lipoprotein
GLFLGHEG_01237 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GLFLGHEG_01238 0.0 Q Polyketide synthase of type I
GLFLGHEG_01239 0.0 Q polyketide synthase
GLFLGHEG_01240 0.0 Q Polyketide synthase of type I
GLFLGHEG_01241 0.0 Q Polyketide synthase of type I
GLFLGHEG_01242 0.0 Q Polyketide synthase of type I
GLFLGHEG_01243 0.0 Q Polyketide synthase of type I
GLFLGHEG_01244 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
GLFLGHEG_01245 8.4e-212 V Beta-lactamase
GLFLGHEG_01246 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GLFLGHEG_01247 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GLFLGHEG_01248 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GLFLGHEG_01249 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GLFLGHEG_01250 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
GLFLGHEG_01251 3.7e-140 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
GLFLGHEG_01252 1.3e-276 speA 4.1.1.19 E Arginine
GLFLGHEG_01253 1.6e-42 yktA S Belongs to the UPF0223 family
GLFLGHEG_01254 4.9e-119 yktB S Belongs to the UPF0637 family
GLFLGHEG_01255 6.3e-24 ykzI
GLFLGHEG_01256 2.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
GLFLGHEG_01257 5.2e-83 ykzC S Acetyltransferase (GNAT) family
GLFLGHEG_01258 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
GLFLGHEG_01259 1.7e-13 sigC S Putative zinc-finger
GLFLGHEG_01260 6.3e-39 ylaE
GLFLGHEG_01261 6.7e-24 S Family of unknown function (DUF5325)
GLFLGHEG_01262 0.0 typA T GTP-binding protein TypA
GLFLGHEG_01263 1.3e-48 ylaH S YlaH-like protein
GLFLGHEG_01264 1e-33 ylaI S protein conserved in bacteria
GLFLGHEG_01265 3.3e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GLFLGHEG_01266 2.8e-194 phoH T ATPase related to phosphate starvation-inducible protein PhoH
GLFLGHEG_01267 1.4e-33 phoH T ATPase related to phosphate starvation-inducible protein PhoH
GLFLGHEG_01268 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GLFLGHEG_01269 7e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
GLFLGHEG_01270 8.7e-44 ylaN S Belongs to the UPF0358 family
GLFLGHEG_01271 3.2e-212 ftsW D Belongs to the SEDS family
GLFLGHEG_01272 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GLFLGHEG_01273 3.8e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
GLFLGHEG_01274 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GLFLGHEG_01275 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
GLFLGHEG_01276 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GLFLGHEG_01277 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
GLFLGHEG_01278 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
GLFLGHEG_01279 1.1e-164 ctaG S cytochrome c oxidase
GLFLGHEG_01280 8.5e-60 ylbA S YugN-like family
GLFLGHEG_01281 8.2e-73 ylbB T COG0517 FOG CBS domain
GLFLGHEG_01282 4.6e-199 ylbC S protein with SCP PR1 domains
GLFLGHEG_01283 6.5e-56 ylbD S Putative coat protein
GLFLGHEG_01284 3.3e-36 ylbE S YlbE-like protein
GLFLGHEG_01285 1.2e-71 ylbF S Belongs to the UPF0342 family
GLFLGHEG_01286 5.5e-43 ylbG S UPF0298 protein
GLFLGHEG_01288 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
GLFLGHEG_01289 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GLFLGHEG_01290 4.4e-217 ylbJ S Sporulation integral membrane protein YlbJ
GLFLGHEG_01291 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
GLFLGHEG_01292 2.1e-188 ylbL T Belongs to the peptidase S16 family
GLFLGHEG_01293 2.3e-229 ylbM S Belongs to the UPF0348 family
GLFLGHEG_01294 7.8e-91 yceD S metal-binding, possibly nucleic acid-binding protein
GLFLGHEG_01295 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GLFLGHEG_01296 4.5e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
GLFLGHEG_01297 1.2e-88 ylbP K n-acetyltransferase
GLFLGHEG_01298 3.6e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GLFLGHEG_01299 2.3e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GLFLGHEG_01300 8.9e-78 mraZ K Belongs to the MraZ family
GLFLGHEG_01301 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GLFLGHEG_01302 2.9e-52 ftsL D Essential cell division protein
GLFLGHEG_01303 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
GLFLGHEG_01304 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
GLFLGHEG_01305 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GLFLGHEG_01306 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GLFLGHEG_01307 1.2e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GLFLGHEG_01308 2.2e-185 spoVE D Belongs to the SEDS family
GLFLGHEG_01309 7.9e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GLFLGHEG_01310 5.6e-169 murB 1.3.1.98 M cell wall formation
GLFLGHEG_01311 8.7e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GLFLGHEG_01312 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GLFLGHEG_01313 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GLFLGHEG_01314 0.0 bpr O COG1404 Subtilisin-like serine proteases
GLFLGHEG_01315 1.9e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
GLFLGHEG_01316 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GLFLGHEG_01317 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GLFLGHEG_01318 4.5e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
GLFLGHEG_01319 3.2e-255 argE 3.5.1.16 E Acetylornithine deacetylase
GLFLGHEG_01320 2.2e-38 ylmC S sporulation protein
GLFLGHEG_01321 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
GLFLGHEG_01322 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GLFLGHEG_01323 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GLFLGHEG_01324 5.2e-41 yggT S membrane
GLFLGHEG_01325 2.1e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
GLFLGHEG_01326 8.9e-68 divIVA D Cell division initiation protein
GLFLGHEG_01327 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GLFLGHEG_01328 3.4e-64 dksA T COG1734 DnaK suppressor protein
GLFLGHEG_01329 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GLFLGHEG_01330 3.9e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GLFLGHEG_01331 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GLFLGHEG_01332 8e-233 pyrP F Xanthine uracil
GLFLGHEG_01333 9e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GLFLGHEG_01334 2.7e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GLFLGHEG_01335 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GLFLGHEG_01336 0.0 carB 6.3.5.5 F Belongs to the CarB family
GLFLGHEG_01337 1.3e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GLFLGHEG_01338 1.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GLFLGHEG_01339 4.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GLFLGHEG_01340 3.8e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GLFLGHEG_01342 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
GLFLGHEG_01343 3.9e-177 cysP P phosphate transporter
GLFLGHEG_01344 2.9e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
GLFLGHEG_01345 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
GLFLGHEG_01346 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
GLFLGHEG_01347 5.8e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
GLFLGHEG_01348 5.9e-80 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
GLFLGHEG_01349 2.2e-54 L COG2963 Transposase and inactivated derivatives
GLFLGHEG_01350 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
GLFLGHEG_01351 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
GLFLGHEG_01352 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
GLFLGHEG_01353 1.3e-154 yloC S stress-induced protein
GLFLGHEG_01354 1.5e-40 ylzA S Belongs to the UPF0296 family
GLFLGHEG_01355 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GLFLGHEG_01356 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GLFLGHEG_01357 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GLFLGHEG_01358 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GLFLGHEG_01359 2.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GLFLGHEG_01360 3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GLFLGHEG_01361 4.6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GLFLGHEG_01362 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GLFLGHEG_01363 1.7e-139 stp 3.1.3.16 T phosphatase
GLFLGHEG_01364 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
GLFLGHEG_01365 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GLFLGHEG_01366 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GLFLGHEG_01367 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
GLFLGHEG_01368 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GLFLGHEG_01369 5.5e-59 asp S protein conserved in bacteria
GLFLGHEG_01370 4.5e-305 yloV S kinase related to dihydroxyacetone kinase
GLFLGHEG_01371 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
GLFLGHEG_01372 3.9e-154 sdaAA 4.3.1.17 E L-serine dehydratase
GLFLGHEG_01373 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GLFLGHEG_01374 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
GLFLGHEG_01375 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GLFLGHEG_01376 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GLFLGHEG_01377 1.8e-128 IQ reductase
GLFLGHEG_01378 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GLFLGHEG_01379 2.6e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GLFLGHEG_01380 0.0 smc D Required for chromosome condensation and partitioning
GLFLGHEG_01381 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GLFLGHEG_01382 1.9e-17 S Phosphotransferase enzyme family
GLFLGHEG_01383 1.5e-67 S Phosphotransferase enzyme family
GLFLGHEG_01384 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GLFLGHEG_01385 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GLFLGHEG_01386 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GLFLGHEG_01387 1.7e-35 ylqC S Belongs to the UPF0109 family
GLFLGHEG_01388 1.3e-61 ylqD S YlqD protein
GLFLGHEG_01389 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GLFLGHEG_01390 8.3e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GLFLGHEG_01391 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GLFLGHEG_01392 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GLFLGHEG_01393 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GLFLGHEG_01394 1.8e-306 ylqG
GLFLGHEG_01395 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
GLFLGHEG_01396 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
GLFLGHEG_01397 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GLFLGHEG_01398 1.9e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
GLFLGHEG_01399 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GLFLGHEG_01400 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GLFLGHEG_01401 7.2e-172 xerC L tyrosine recombinase XerC
GLFLGHEG_01402 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GLFLGHEG_01403 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GLFLGHEG_01404 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GLFLGHEG_01405 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
GLFLGHEG_01406 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
GLFLGHEG_01407 2.5e-31 fliE N Flagellar hook-basal body
GLFLGHEG_01408 1.4e-263 fliF N The M ring may be actively involved in energy transduction
GLFLGHEG_01409 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GLFLGHEG_01410 3.7e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
GLFLGHEG_01411 5.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
GLFLGHEG_01412 4.5e-71 fliJ N Flagellar biosynthesis chaperone
GLFLGHEG_01413 4.4e-48 ylxF S MgtE intracellular N domain
GLFLGHEG_01414 1.2e-204 fliK N Flagellar hook-length control protein
GLFLGHEG_01415 1.4e-72 flgD N Flagellar basal body rod modification protein
GLFLGHEG_01416 4e-139 flgG N Flagellar basal body rod
GLFLGHEG_01417 9.2e-58 fliL N Controls the rotational direction of flagella during chemotaxis
GLFLGHEG_01418 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GLFLGHEG_01419 9.6e-187 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GLFLGHEG_01420 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
GLFLGHEG_01421 1.9e-110 fliZ N Flagellar biosynthesis protein, FliO
GLFLGHEG_01422 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
GLFLGHEG_01423 2e-37 fliQ N Role in flagellar biosynthesis
GLFLGHEG_01424 3.4e-130 fliR N Flagellar biosynthetic protein FliR
GLFLGHEG_01425 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GLFLGHEG_01426 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GLFLGHEG_01427 3e-193 flhF N Flagellar biosynthesis regulator FlhF
GLFLGHEG_01428 1.6e-155 flhG D Belongs to the ParA family
GLFLGHEG_01429 2.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
GLFLGHEG_01430 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
GLFLGHEG_01431 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
GLFLGHEG_01432 5.4e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
GLFLGHEG_01433 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
GLFLGHEG_01434 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GLFLGHEG_01435 2.7e-50 ylxL
GLFLGHEG_01436 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
GLFLGHEG_01437 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GLFLGHEG_01438 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GLFLGHEG_01439 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GLFLGHEG_01440 2.2e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GLFLGHEG_01441 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
GLFLGHEG_01442 1.9e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
GLFLGHEG_01443 1.5e-233 rasP M zinc metalloprotease
GLFLGHEG_01444 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GLFLGHEG_01445 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GLFLGHEG_01446 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
GLFLGHEG_01447 5.4e-206 nusA K Participates in both transcription termination and antitermination
GLFLGHEG_01448 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
GLFLGHEG_01449 1.8e-47 ylxQ J ribosomal protein
GLFLGHEG_01450 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GLFLGHEG_01451 3.9e-44 ylxP S protein conserved in bacteria
GLFLGHEG_01452 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GLFLGHEG_01453 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GLFLGHEG_01454 1e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GLFLGHEG_01455 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GLFLGHEG_01456 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GLFLGHEG_01457 1.8e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
GLFLGHEG_01458 3.6e-235 pepR S Belongs to the peptidase M16 family
GLFLGHEG_01459 2.6e-42 ymxH S YlmC YmxH family
GLFLGHEG_01460 1.2e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
GLFLGHEG_01461 1.1e-22 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
GLFLGHEG_01462 4.7e-48 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
GLFLGHEG_01463 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GLFLGHEG_01464 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
GLFLGHEG_01465 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GLFLGHEG_01466 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GLFLGHEG_01467 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
GLFLGHEG_01468 6.3e-31 S YlzJ-like protein
GLFLGHEG_01469 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GLFLGHEG_01470 1.8e-133 ymfC K Transcriptional regulator
GLFLGHEG_01471 2.4e-229 ymfD EGP Major facilitator Superfamily
GLFLGHEG_01472 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
GLFLGHEG_01473 0.0 ydgH S drug exporters of the RND superfamily
GLFLGHEG_01474 1.2e-238 ymfF S Peptidase M16
GLFLGHEG_01475 7.5e-244 ymfH S zinc protease
GLFLGHEG_01476 8.6e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
GLFLGHEG_01477 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
GLFLGHEG_01478 3.5e-143 ymfK S Protein of unknown function (DUF3388)
GLFLGHEG_01479 1.7e-125 ymfM S protein conserved in bacteria
GLFLGHEG_01480 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GLFLGHEG_01481 1.7e-232 cinA 3.5.1.42 S Belongs to the CinA family
GLFLGHEG_01482 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GLFLGHEG_01483 5e-194 pbpX V Beta-lactamase
GLFLGHEG_01484 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
GLFLGHEG_01485 4.9e-153 ymdB S protein conserved in bacteria
GLFLGHEG_01486 1.2e-36 spoVS S Stage V sporulation protein S
GLFLGHEG_01487 1.5e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
GLFLGHEG_01488 6.7e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GLFLGHEG_01489 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GLFLGHEG_01490 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
GLFLGHEG_01491 1.7e-88 cotE S Spore coat protein
GLFLGHEG_01492 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GLFLGHEG_01493 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GLFLGHEG_01494 1.3e-68 L Belongs to the 'phage' integrase family
GLFLGHEG_01495 9.1e-31
GLFLGHEG_01497 2.2e-128 pksB 3.1.2.6 S Polyketide biosynthesis
GLFLGHEG_01498 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GLFLGHEG_01499 1.1e-183 pksD Q Acyl transferase domain
GLFLGHEG_01500 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GLFLGHEG_01501 1.9e-34 acpK IQ Phosphopantetheine attachment site
GLFLGHEG_01502 8.2e-243 pksG 2.3.3.10 I synthase
GLFLGHEG_01503 3.1e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
GLFLGHEG_01504 1.9e-138 pksI I Belongs to the enoyl-CoA hydratase isomerase family
GLFLGHEG_01505 0.0 rhiB IQ polyketide synthase
GLFLGHEG_01506 0.0 Q Polyketide synthase of type I
GLFLGHEG_01507 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
GLFLGHEG_01508 0.0 dhbF IQ polyketide synthase
GLFLGHEG_01509 0.0 pks13 HQ Beta-ketoacyl synthase
GLFLGHEG_01510 2.4e-231 cypA C Cytochrome P450
GLFLGHEG_01511 6.4e-78 nucB M Deoxyribonuclease NucA/NucB
GLFLGHEG_01512 3.6e-118 yoaK S Membrane
GLFLGHEG_01513 1.4e-62 ymzB
GLFLGHEG_01514 1.8e-256 aprX O Belongs to the peptidase S8 family
GLFLGHEG_01516 4.1e-127 ymaC S Replication protein
GLFLGHEG_01517 3.9e-78 ymaD O redox protein, regulator of disulfide bond formation
GLFLGHEG_01518 5.2e-54 ebrB P Small Multidrug Resistance protein
GLFLGHEG_01519 3.1e-48 ebrA P Small Multidrug Resistance protein
GLFLGHEG_01521 4.1e-47 ymaF S YmaF family
GLFLGHEG_01522 9.6e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GLFLGHEG_01523 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
GLFLGHEG_01524 8.5e-44
GLFLGHEG_01525 1.8e-20 ymzA
GLFLGHEG_01526 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
GLFLGHEG_01527 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GLFLGHEG_01528 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GLFLGHEG_01529 9e-110 ymaB S MutT family
GLFLGHEG_01530 1.9e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GLFLGHEG_01531 2.7e-79 spoVK O stage V sporulation protein K
GLFLGHEG_01532 3.9e-69 spoVK O stage V sporulation protein K
GLFLGHEG_01533 2.7e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GLFLGHEG_01534 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
GLFLGHEG_01535 4.3e-68 glnR K transcriptional
GLFLGHEG_01536 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
GLFLGHEG_01537 1.2e-213 mrjp G Major royal jelly protein
GLFLGHEG_01538 3e-182 xynT G MFS/sugar transport protein
GLFLGHEG_01539 1.5e-46 xynT G MFS/sugar transport protein
GLFLGHEG_01540 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
GLFLGHEG_01541 2.1e-216 xylR GK ROK family
GLFLGHEG_01542 3.2e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
GLFLGHEG_01543 2.7e-285 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
GLFLGHEG_01544 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
GLFLGHEG_01547 5.4e-17
GLFLGHEG_01548 1.9e-186 adhP 1.1.1.1 C alcohol dehydrogenase
GLFLGHEG_01549 8.6e-11 ccmM S Bacterial transferase hexapeptide (six repeats)
GLFLGHEG_01550 4.2e-16
GLFLGHEG_01552 1.8e-43
GLFLGHEG_01554 3.1e-144 yoaP 3.1.3.18 K YoaP-like
GLFLGHEG_01555 9.8e-88 J Acetyltransferase (GNAT) domain
GLFLGHEG_01556 1.9e-58
GLFLGHEG_01559 3.1e-118 ynaE S Domain of unknown function (DUF3885)
GLFLGHEG_01560 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLFLGHEG_01561 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
GLFLGHEG_01563 2.5e-63 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GLFLGHEG_01564 3.5e-94 yvgO
GLFLGHEG_01566 0.0 yobO M Pectate lyase superfamily protein
GLFLGHEG_01567 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
GLFLGHEG_01568 8.7e-145 yndL S Replication protein
GLFLGHEG_01569 1.6e-07
GLFLGHEG_01570 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
GLFLGHEG_01571 2.4e-72 yndM S Protein of unknown function (DUF2512)
GLFLGHEG_01572 7.1e-13 yoaW
GLFLGHEG_01573 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GLFLGHEG_01574 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
GLFLGHEG_01575 2.2e-111 yneB L resolvase
GLFLGHEG_01576 9.8e-33 ynzC S UPF0291 protein
GLFLGHEG_01577 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GLFLGHEG_01578 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
GLFLGHEG_01579 2.3e-28 yneF S UPF0154 protein
GLFLGHEG_01580 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
GLFLGHEG_01581 1.7e-125 ccdA O cytochrome c biogenesis protein
GLFLGHEG_01582 1.4e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
GLFLGHEG_01583 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
GLFLGHEG_01584 8.5e-75 yneK S Protein of unknown function (DUF2621)
GLFLGHEG_01585 2.9e-63 hspX O Spore coat protein
GLFLGHEG_01586 2.3e-19 sspP S Belongs to the SspP family
GLFLGHEG_01587 7.5e-15 sspO S Belongs to the SspO family
GLFLGHEG_01588 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GLFLGHEG_01589 1.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GLFLGHEG_01591 2.7e-33 tlp S Belongs to the Tlp family
GLFLGHEG_01592 8.3e-75 yneP S Thioesterase-like superfamily
GLFLGHEG_01593 4.4e-54 yneQ
GLFLGHEG_01594 4.9e-50 yneR S Belongs to the HesB IscA family
GLFLGHEG_01595 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GLFLGHEG_01596 1.5e-68 yccU S CoA-binding protein
GLFLGHEG_01597 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GLFLGHEG_01598 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GLFLGHEG_01599 6e-13
GLFLGHEG_01600 5.1e-41 ynfC
GLFLGHEG_01601 1.6e-250 agcS E Sodium alanine symporter
GLFLGHEG_01602 1e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
GLFLGHEG_01603 6.9e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
GLFLGHEG_01604 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
GLFLGHEG_01605 1.9e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
GLFLGHEG_01606 6e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GLFLGHEG_01607 1.7e-182 kdgR_1 K transcriptional
GLFLGHEG_01608 1.5e-223 exuT G Sugar (and other) transporter
GLFLGHEG_01609 5.8e-157 yndG S DoxX-like family
GLFLGHEG_01610 1.1e-78 yndH S Domain of unknown function (DUF4166)
GLFLGHEG_01611 2e-302 yndJ S YndJ-like protein
GLFLGHEG_01612 1.9e-82
GLFLGHEG_01613 8.3e-63 V ABC transporter
GLFLGHEG_01614 3.2e-11
GLFLGHEG_01615 2.6e-216 S Platelet-activating factor acetylhydrolase, isoform II
GLFLGHEG_01616 1.2e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
GLFLGHEG_01617 2.8e-51 S Domain of unknown function (DUF4870)
GLFLGHEG_01618 1.9e-232 T PhoQ Sensor
GLFLGHEG_01619 7.6e-129 T Transcriptional regulatory protein, C terminal
GLFLGHEG_01620 5.1e-253 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
GLFLGHEG_01621 1.1e-289 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
GLFLGHEG_01622 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_01623 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_01624 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_01625 5.3e-223 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GLFLGHEG_01626 1.8e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
GLFLGHEG_01627 7.1e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GLFLGHEG_01628 3.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GLFLGHEG_01629 1.9e-256 yxjC EG COG2610 H gluconate symporter and related permeases
GLFLGHEG_01630 9.5e-225 bioI 1.14.14.46 C Cytochrome P450
GLFLGHEG_01631 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GLFLGHEG_01632 1.3e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GLFLGHEG_01633 1.2e-208 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GLFLGHEG_01634 1.7e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
GLFLGHEG_01635 3e-147 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GLFLGHEG_01636 3.7e-72 yngA S membrane
GLFLGHEG_01637 4.3e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GLFLGHEG_01638 4.1e-104 yngC S SNARE associated Golgi protein
GLFLGHEG_01639 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GLFLGHEG_01640 5.8e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
GLFLGHEG_01641 2.5e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
GLFLGHEG_01642 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
GLFLGHEG_01643 1.2e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
GLFLGHEG_01644 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GLFLGHEG_01645 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
GLFLGHEG_01646 2e-304 yngK T Glycosyl hydrolase-like 10
GLFLGHEG_01647 4.1e-65 yngL S Protein of unknown function (DUF1360)
GLFLGHEG_01648 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
GLFLGHEG_01649 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_01650 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_01651 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_01652 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_01653 2.5e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
GLFLGHEG_01654 2.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
GLFLGHEG_01655 1e-246 yoeA V MATE efflux family protein
GLFLGHEG_01656 5e-96 yoeB S IseA DL-endopeptidase inhibitor
GLFLGHEG_01657 4.4e-205 yobL S Bacterial EndoU nuclease
GLFLGHEG_01658 2.6e-26 S SMI1 / KNR4 family
GLFLGHEG_01660 6.7e-70 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GLFLGHEG_01661 6.9e-61 S Pfam:Phage_holin_4_1
GLFLGHEG_01664 1.8e-152 S Domain of unknown function (DUF2479)
GLFLGHEG_01665 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
GLFLGHEG_01666 1.6e-225 NU Prophage endopeptidase tail
GLFLGHEG_01667 7.1e-110 S Phage tail protein
GLFLGHEG_01668 0.0 S peptidoglycan catabolic process
GLFLGHEG_01669 5.7e-11
GLFLGHEG_01670 4.6e-23
GLFLGHEG_01671 3.4e-61
GLFLGHEG_01672 8.7e-31
GLFLGHEG_01673 4.6e-48 S Bacteriophage HK97-gp10, putative tail-component
GLFLGHEG_01674 3.6e-15 S Phage head-tail joining protein
GLFLGHEG_01675 1.5e-24 S Phage gp6-like head-tail connector protein
GLFLGHEG_01676 3.8e-33 S peptidoglycan catabolic process
GLFLGHEG_01678 4.2e-180 S capsid protein
GLFLGHEG_01679 1.2e-109 S peptidase activity
GLFLGHEG_01680 7.1e-239 S Phage portal protein
GLFLGHEG_01681 1e-10
GLFLGHEG_01682 3.7e-230 S Phage Terminase
GLFLGHEG_01683 3.9e-87 S Phage terminase, small subunit
GLFLGHEG_01684 2.2e-22
GLFLGHEG_01685 1.4e-68 S HNH endonuclease
GLFLGHEG_01686 2.2e-47
GLFLGHEG_01688 1e-72 L Phage integrase family
GLFLGHEG_01689 5.7e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
GLFLGHEG_01691 1.1e-55 D nuclear chromosome segregation
GLFLGHEG_01693 3.4e-47
GLFLGHEG_01695 8e-106 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
GLFLGHEG_01698 4.7e-15 yqaO S Phage-like element PBSX protein XtrA
GLFLGHEG_01701 7.6e-28
GLFLGHEG_01704 2.8e-42 dnaC L IstB-like ATP binding protein
GLFLGHEG_01705 3.7e-85 ybl78 L Conserved phage C-terminus (Phg_2220_C)
GLFLGHEG_01707 3.7e-38 S Domain of unknown function (DUF771)
GLFLGHEG_01709 7.8e-22 K Helix-turn-helix XRE-family like proteins
GLFLGHEG_01712 4.3e-70
GLFLGHEG_01713 6.5e-119 L Phage integrase family
GLFLGHEG_01715 2.2e-96 L Integrase
GLFLGHEG_01716 1.8e-34 yoeD G Helix-turn-helix domain
GLFLGHEG_01717 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
GLFLGHEG_01718 1.2e-200 ybcL EGP Major facilitator Superfamily
GLFLGHEG_01719 6.7e-50 ybzH K Helix-turn-helix domain
GLFLGHEG_01720 2.8e-271 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GLFLGHEG_01721 2.8e-157 gltR1 K Transcriptional regulator
GLFLGHEG_01722 1.1e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GLFLGHEG_01723 1.9e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
GLFLGHEG_01724 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
GLFLGHEG_01725 8.7e-146 gltC K Transcriptional regulator
GLFLGHEG_01726 1.3e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GLFLGHEG_01727 2e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GLFLGHEG_01728 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
GLFLGHEG_01729 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GLFLGHEG_01730 2.2e-40 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GLFLGHEG_01731 9.3e-141 yoxB
GLFLGHEG_01732 1.9e-204 yoaB EGP Major facilitator Superfamily
GLFLGHEG_01733 5.9e-277 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
GLFLGHEG_01734 4.3e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GLFLGHEG_01735 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GLFLGHEG_01737 1e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
GLFLGHEG_01738 3.9e-44
GLFLGHEG_01739 3.6e-55 S SMI1-KNR4 cell-wall
GLFLGHEG_01740 2.6e-298 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
GLFLGHEG_01741 5.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
GLFLGHEG_01742 3.5e-134 yobQ K helix_turn_helix, arabinose operon control protein
GLFLGHEG_01743 1.3e-94 yobS K Transcriptional regulator
GLFLGHEG_01744 1.9e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
GLFLGHEG_01745 3.2e-92 yobW
GLFLGHEG_01746 3.4e-55 czrA K transcriptional
GLFLGHEG_01747 6e-120 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GLFLGHEG_01748 2.8e-91 yozB S membrane
GLFLGHEG_01749 5.6e-141 yocB J Protein required for attachment to host cells
GLFLGHEG_01750 1.9e-94 yocC
GLFLGHEG_01751 1.1e-186 yocD 3.4.17.13 V peptidase S66
GLFLGHEG_01753 1.7e-114 yocH CBM50 M COG1388 FOG LysM repeat
GLFLGHEG_01754 0.0 recQ 3.6.4.12 L DNA helicase
GLFLGHEG_01755 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GLFLGHEG_01757 9.5e-54 dksA T general stress protein
GLFLGHEG_01758 5.9e-10 yocL
GLFLGHEG_01759 9.8e-09 yocN
GLFLGHEG_01760 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
GLFLGHEG_01761 3.8e-44 yozN
GLFLGHEG_01762 8.5e-37 yocN
GLFLGHEG_01763 2.4e-56 yozO S Bacterial PH domain
GLFLGHEG_01765 1.6e-31 yozC
GLFLGHEG_01766 9.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
GLFLGHEG_01767 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
GLFLGHEG_01768 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
GLFLGHEG_01769 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GLFLGHEG_01770 2.5e-159 yocS S -transporter
GLFLGHEG_01771 4.4e-143 S Metallo-beta-lactamase superfamily
GLFLGHEG_01772 1.9e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
GLFLGHEG_01773 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
GLFLGHEG_01774 0.0 yojO P Von Willebrand factor
GLFLGHEG_01775 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
GLFLGHEG_01776 3.6e-90 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GLFLGHEG_01777 9.5e-228 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
GLFLGHEG_01778 3e-226 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
GLFLGHEG_01779 7.4e-112 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GLFLGHEG_01781 4.8e-241 norM V Multidrug efflux pump
GLFLGHEG_01782 2.9e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GLFLGHEG_01783 4.3e-126 yojG S deacetylase
GLFLGHEG_01784 3.7e-60 yojF S Protein of unknown function (DUF1806)
GLFLGHEG_01785 4.9e-23
GLFLGHEG_01786 2.3e-162 rarD S -transporter
GLFLGHEG_01787 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
GLFLGHEG_01789 3.5e-67 yodA S tautomerase
GLFLGHEG_01790 5.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
GLFLGHEG_01791 4e-56 yodB K transcriptional
GLFLGHEG_01792 4.5e-106 yodC C nitroreductase
GLFLGHEG_01793 1.3e-110 mhqD S Carboxylesterase
GLFLGHEG_01794 3.5e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
GLFLGHEG_01795 1.4e-19 S Protein of unknown function (DUF3311)
GLFLGHEG_01796 4.6e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GLFLGHEG_01797 1.2e-282 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
GLFLGHEG_01798 7.8e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GLFLGHEG_01799 5.2e-133 yydK K Transcriptional regulator
GLFLGHEG_01800 1e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
GLFLGHEG_01801 2.8e-128 yodH Q Methyltransferase
GLFLGHEG_01802 1.1e-34 yodI
GLFLGHEG_01803 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
GLFLGHEG_01804 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
GLFLGHEG_01806 3.3e-55 yodL S YodL-like
GLFLGHEG_01807 1.1e-102 yodM 3.6.1.27 I Acid phosphatase homologues
GLFLGHEG_01808 6.2e-24 yozD S YozD-like protein
GLFLGHEG_01810 4.9e-125 yodN
GLFLGHEG_01811 4.1e-36 yozE S Belongs to the UPF0346 family
GLFLGHEG_01812 2e-45 yokU S YokU-like protein, putative antitoxin
GLFLGHEG_01813 7.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
GLFLGHEG_01814 4.3e-158 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
GLFLGHEG_01815 1.5e-255 yodQ 3.5.1.16 E Acetylornithine deacetylase
GLFLGHEG_01816 6.1e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GLFLGHEG_01817 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GLFLGHEG_01818 1.8e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GLFLGHEG_01820 3.2e-144 yiiD K acetyltransferase
GLFLGHEG_01821 3.2e-247 cgeD M maturation of the outermost layer of the spore
GLFLGHEG_01822 1.1e-41 cgeC
GLFLGHEG_01823 1.6e-52 cgeA
GLFLGHEG_01824 1.2e-180 cgeB S Spore maturation protein
GLFLGHEG_01825 1e-220 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
GLFLGHEG_01826 1.1e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
GLFLGHEG_01827 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GLFLGHEG_01828 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GLFLGHEG_01829 1.4e-66 ypoP K transcriptional
GLFLGHEG_01830 5.5e-98 ypmS S protein conserved in bacteria
GLFLGHEG_01831 8.9e-136 ypmR E GDSL-like Lipase/Acylhydrolase
GLFLGHEG_01832 3e-107 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
GLFLGHEG_01833 2.6e-39 ypmP S Protein of unknown function (DUF2535)
GLFLGHEG_01834 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GLFLGHEG_01835 5e-179 pspF K Transcriptional regulator
GLFLGHEG_01836 9.3e-110 hlyIII S protein, Hemolysin III
GLFLGHEG_01837 1.8e-113 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GLFLGHEG_01838 4.8e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GLFLGHEG_01839 1.5e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GLFLGHEG_01840 2.7e-114 ypjP S YpjP-like protein
GLFLGHEG_01841 1.3e-129 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
GLFLGHEG_01842 1e-75 yphP S Belongs to the UPF0403 family
GLFLGHEG_01843 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GLFLGHEG_01844 2.3e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
GLFLGHEG_01845 5.9e-98 ypgQ S phosphohydrolase
GLFLGHEG_01846 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
GLFLGHEG_01847 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GLFLGHEG_01848 3.2e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
GLFLGHEG_01849 1e-30 cspD K Cold-shock protein
GLFLGHEG_01850 1.3e-11 degR
GLFLGHEG_01851 1.2e-36 S Protein of unknown function (DUF2564)
GLFLGHEG_01852 1.5e-28 ypeQ S Zinc-finger
GLFLGHEG_01853 1.5e-123 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
GLFLGHEG_01854 8.9e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GLFLGHEG_01855 1.6e-67 rnhA 3.1.26.4 L Ribonuclease
GLFLGHEG_01857 4.1e-164 polA 2.7.7.7 L 5'3' exonuclease
GLFLGHEG_01859 3.5e-39 ypbS S Protein of unknown function (DUF2533)
GLFLGHEG_01860 0.0 ypbR S Dynamin family
GLFLGHEG_01861 2.5e-89 ypbQ S protein conserved in bacteria
GLFLGHEG_01862 2.5e-203 bcsA Q Naringenin-chalcone synthase
GLFLGHEG_01863 1.5e-109 J Acetyltransferase (GNAT) domain
GLFLGHEG_01864 5.8e-49 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
GLFLGHEG_01866 3.9e-61 ydfR S Protein of unknown function (DUF421)
GLFLGHEG_01867 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
GLFLGHEG_01869 1.3e-235 pbuX F xanthine
GLFLGHEG_01870 1.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GLFLGHEG_01871 5.4e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GLFLGHEG_01872 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
GLFLGHEG_01874 6.6e-22 S YpzG-like protein
GLFLGHEG_01875 4.2e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GLFLGHEG_01876 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GLFLGHEG_01877 4.8e-99 ypsA S Belongs to the UPF0398 family
GLFLGHEG_01878 9.9e-33 cotD S Inner spore coat protein D
GLFLGHEG_01880 1.1e-236 yprB L RNase_H superfamily
GLFLGHEG_01881 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
GLFLGHEG_01882 7.9e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
GLFLGHEG_01883 6.5e-72 hspX O Belongs to the small heat shock protein (HSP20) family
GLFLGHEG_01884 1.3e-44 yppG S YppG-like protein
GLFLGHEG_01886 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
GLFLGHEG_01889 7.5e-188 yppC S Protein of unknown function (DUF2515)
GLFLGHEG_01890 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GLFLGHEG_01891 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GLFLGHEG_01892 8.2e-90 ypoC
GLFLGHEG_01893 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GLFLGHEG_01894 3e-130 dnaD L DNA replication protein DnaD
GLFLGHEG_01895 2.9e-251 asnS 6.1.1.22 J asparaginyl-tRNA
GLFLGHEG_01896 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
GLFLGHEG_01897 4e-81 ypmB S protein conserved in bacteria
GLFLGHEG_01898 6.7e-23 ypmA S Protein of unknown function (DUF4264)
GLFLGHEG_01899 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GLFLGHEG_01900 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GLFLGHEG_01901 1e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GLFLGHEG_01902 3.8e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
GLFLGHEG_01903 4.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GLFLGHEG_01904 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GLFLGHEG_01905 2.2e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
GLFLGHEG_01906 6.2e-131 bshB1 S proteins, LmbE homologs
GLFLGHEG_01907 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
GLFLGHEG_01908 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GLFLGHEG_01909 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
GLFLGHEG_01910 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
GLFLGHEG_01911 1.2e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
GLFLGHEG_01912 5.1e-142 ypjB S sporulation protein
GLFLGHEG_01913 1.2e-103 ypjA S membrane
GLFLGHEG_01914 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
GLFLGHEG_01915 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
GLFLGHEG_01916 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
GLFLGHEG_01917 3.2e-77 ypiF S Protein of unknown function (DUF2487)
GLFLGHEG_01918 2.1e-99 ypiB S Belongs to the UPF0302 family
GLFLGHEG_01919 1.7e-232 S COG0457 FOG TPR repeat
GLFLGHEG_01920 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GLFLGHEG_01921 6.6e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
GLFLGHEG_01922 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GLFLGHEG_01923 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GLFLGHEG_01924 4.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GLFLGHEG_01925 4.7e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
GLFLGHEG_01926 7.3e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
GLFLGHEG_01927 4.1e-160 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GLFLGHEG_01928 4.7e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GLFLGHEG_01929 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
GLFLGHEG_01930 7.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GLFLGHEG_01931 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GLFLGHEG_01932 1.2e-139 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
GLFLGHEG_01933 1.2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GLFLGHEG_01934 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GLFLGHEG_01935 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GLFLGHEG_01936 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
GLFLGHEG_01937 6.6e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
GLFLGHEG_01938 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
GLFLGHEG_01939 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GLFLGHEG_01940 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GLFLGHEG_01941 3.6e-134 yphF
GLFLGHEG_01942 3.3e-16 yphE S Protein of unknown function (DUF2768)
GLFLGHEG_01943 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GLFLGHEG_01944 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GLFLGHEG_01945 1.4e-104 yphA
GLFLGHEG_01946 4.7e-08 S YpzI-like protein
GLFLGHEG_01947 5.9e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GLFLGHEG_01948 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
GLFLGHEG_01949 3.3e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GLFLGHEG_01950 1.4e-12 S Family of unknown function (DUF5359)
GLFLGHEG_01951 1.6e-61 ypfA M Flagellar protein YcgR
GLFLGHEG_01952 8.7e-251 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
GLFLGHEG_01953 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
GLFLGHEG_01954 6.9e-77 prsW S Involved in the degradation of specific anti-sigma factors
GLFLGHEG_01955 3.6e-27 prsW S Involved in the degradation of specific anti-sigma factors
GLFLGHEG_01956 9e-189 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
GLFLGHEG_01957 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
GLFLGHEG_01958 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GLFLGHEG_01959 5.3e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
GLFLGHEG_01960 1.7e-84 ypbF S Protein of unknown function (DUF2663)
GLFLGHEG_01961 3.3e-77 ypbE M Lysin motif
GLFLGHEG_01962 2.9e-99 ypbD S metal-dependent membrane protease
GLFLGHEG_01963 4.2e-272 recQ 3.6.4.12 L DNA helicase
GLFLGHEG_01964 2.7e-199 ypbB 5.1.3.1 S protein conserved in bacteria
GLFLGHEG_01965 3.6e-41 fer C Ferredoxin
GLFLGHEG_01966 1.4e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GLFLGHEG_01967 1.3e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GLFLGHEG_01968 1.2e-197 rsiX
GLFLGHEG_01969 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
GLFLGHEG_01970 0.0 resE 2.7.13.3 T Histidine kinase
GLFLGHEG_01971 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GLFLGHEG_01972 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
GLFLGHEG_01973 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
GLFLGHEG_01974 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
GLFLGHEG_01975 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GLFLGHEG_01976 2.9e-88 spmB S Spore maturation protein
GLFLGHEG_01977 2e-103 spmA S Spore maturation protein
GLFLGHEG_01978 6.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
GLFLGHEG_01979 1.3e-93 ypuI S Protein of unknown function (DUF3907)
GLFLGHEG_01980 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GLFLGHEG_01981 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GLFLGHEG_01983 6.4e-93 ypuF S Domain of unknown function (DUF309)
GLFLGHEG_01984 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GLFLGHEG_01985 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GLFLGHEG_01986 1.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GLFLGHEG_01987 2.9e-111 ribE 2.5.1.9 H Riboflavin synthase
GLFLGHEG_01988 2.8e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GLFLGHEG_01989 1.7e-49 ypuD
GLFLGHEG_01990 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
GLFLGHEG_01991 8.2e-82 ccdC1 O Protein of unknown function (DUF1453)
GLFLGHEG_01992 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GLFLGHEG_01993 6e-155 ypuA S Secreted protein
GLFLGHEG_01994 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GLFLGHEG_01995 1.4e-270 spoVAF EG Stage V sporulation protein AF
GLFLGHEG_01996 1.8e-110 spoVAEA S stage V sporulation protein
GLFLGHEG_01997 3.8e-57 spoVAEB S stage V sporulation protein
GLFLGHEG_01998 3.5e-70 spoVAD I Stage V sporulation protein AD
GLFLGHEG_01999 2.8e-89 spoVAD I Stage V sporulation protein AD
GLFLGHEG_02000 2.1e-79 spoVAC S stage V sporulation protein AC
GLFLGHEG_02001 3e-60 spoVAB S Stage V sporulation protein AB
GLFLGHEG_02002 3.7e-111 spoVAA S Stage V sporulation protein AA
GLFLGHEG_02003 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GLFLGHEG_02004 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
GLFLGHEG_02005 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
GLFLGHEG_02006 4.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
GLFLGHEG_02007 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GLFLGHEG_02008 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GLFLGHEG_02009 1.8e-164 xerD L recombinase XerD
GLFLGHEG_02010 9.2e-36 S Protein of unknown function (DUF4227)
GLFLGHEG_02011 1.9e-80 fur P Belongs to the Fur family
GLFLGHEG_02012 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
GLFLGHEG_02014 1.7e-34 yqkK
GLFLGHEG_02015 5.7e-22
GLFLGHEG_02016 7.7e-244 mleA 1.1.1.38 C malic enzyme
GLFLGHEG_02017 2.5e-240 mleN C Na H antiporter
GLFLGHEG_02018 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
GLFLGHEG_02019 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
GLFLGHEG_02020 3e-57 ansR K Transcriptional regulator
GLFLGHEG_02021 2.4e-220 yqxK 3.6.4.12 L DNA helicase
GLFLGHEG_02022 8.7e-72 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
GLFLGHEG_02024 3.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
GLFLGHEG_02026 6.2e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
GLFLGHEG_02027 3.2e-39 yqkC S Protein of unknown function (DUF2552)
GLFLGHEG_02028 2.9e-60 yqkB S Belongs to the HesB IscA family
GLFLGHEG_02029 7.7e-177 yqkA K GrpB protein
GLFLGHEG_02030 1.6e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
GLFLGHEG_02031 6.6e-89 yqjY K acetyltransferase
GLFLGHEG_02032 9.4e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GLFLGHEG_02033 7.6e-58 S YolD-like protein
GLFLGHEG_02035 2.5e-176 yueF S transporter activity
GLFLGHEG_02037 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GLFLGHEG_02038 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
GLFLGHEG_02039 1.8e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
GLFLGHEG_02040 4.2e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
GLFLGHEG_02041 7.2e-175 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
GLFLGHEG_02042 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GLFLGHEG_02043 7.5e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
GLFLGHEG_02044 6.4e-240 pksG 2.3.3.10 I synthase
GLFLGHEG_02045 1.7e-218 eryK 1.14.13.154 C Cytochrome P450
GLFLGHEG_02046 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GLFLGHEG_02047 0.0 Q Polyketide synthase of type I
GLFLGHEG_02048 0.0 pfaA Q Polyketide synthase of type I
GLFLGHEG_02049 0.0 pksJ Q Polyketide synthase of type I
GLFLGHEG_02050 0.0 Q Polyketide synthase of type I
GLFLGHEG_02051 0.0 1.1.1.320 Q Polyketide synthase of type I
GLFLGHEG_02052 0.0 pksJ Q Polyketide synthase of type I
GLFLGHEG_02053 5.5e-130 IQ reductase
GLFLGHEG_02054 4.1e-248 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GLFLGHEG_02057 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GLFLGHEG_02058 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
GLFLGHEG_02059 5.8e-163 K LysR substrate binding domain
GLFLGHEG_02060 2.5e-50 S GlpM protein
GLFLGHEG_02061 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
GLFLGHEG_02062 1.3e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GLFLGHEG_02063 3.3e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GLFLGHEG_02064 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GLFLGHEG_02065 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GLFLGHEG_02066 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GLFLGHEG_02067 2.4e-25 yqzJ
GLFLGHEG_02068 4.6e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GLFLGHEG_02069 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
GLFLGHEG_02070 4.8e-290 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GLFLGHEG_02071 1.1e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
GLFLGHEG_02073 5.4e-95 yqjB S protein conserved in bacteria
GLFLGHEG_02074 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
GLFLGHEG_02075 1e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GLFLGHEG_02076 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
GLFLGHEG_02077 9e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
GLFLGHEG_02078 1e-75 yqiW S Belongs to the UPF0403 family
GLFLGHEG_02079 1.6e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GLFLGHEG_02080 1.8e-202 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GLFLGHEG_02081 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GLFLGHEG_02082 7.5e-167 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GLFLGHEG_02083 1.8e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GLFLGHEG_02084 7.5e-208 buk 2.7.2.7 C Belongs to the acetokinase family
GLFLGHEG_02085 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
GLFLGHEG_02086 2.8e-152 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
GLFLGHEG_02087 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
GLFLGHEG_02088 3.2e-34 yqzF S Protein of unknown function (DUF2627)
GLFLGHEG_02089 1.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GLFLGHEG_02090 2e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
GLFLGHEG_02091 1.4e-161 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
GLFLGHEG_02092 9.9e-21 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
GLFLGHEG_02093 1.6e-205 mmgC I acyl-CoA dehydrogenase
GLFLGHEG_02094 4.8e-154 hbdA 1.1.1.157 I Dehydrogenase
GLFLGHEG_02095 1.7e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
GLFLGHEG_02096 3.3e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GLFLGHEG_02097 1.2e-104 amiC 3.5.1.28 M Cell wall hydrolase autolysin
GLFLGHEG_02098 2.5e-17
GLFLGHEG_02099 1.5e-101 ytaF P Probably functions as a manganese efflux pump
GLFLGHEG_02100 1.8e-113 K Protein of unknown function (DUF1232)
GLFLGHEG_02102 3.2e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
GLFLGHEG_02105 1.4e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GLFLGHEG_02106 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
GLFLGHEG_02107 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
GLFLGHEG_02108 2.7e-305 recN L May be involved in recombinational repair of damaged DNA
GLFLGHEG_02109 3.9e-78 argR K Regulates arginine biosynthesis genes
GLFLGHEG_02110 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
GLFLGHEG_02111 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GLFLGHEG_02112 2.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GLFLGHEG_02113 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GLFLGHEG_02114 5.1e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GLFLGHEG_02115 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GLFLGHEG_02116 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GLFLGHEG_02117 8.1e-67 yqhY S protein conserved in bacteria
GLFLGHEG_02118 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GLFLGHEG_02119 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GLFLGHEG_02120 2.5e-62 spoIIIAH S SpoIIIAH-like protein
GLFLGHEG_02121 3.4e-118 spoIIIAG S stage III sporulation protein AG
GLFLGHEG_02122 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
GLFLGHEG_02123 1.4e-199 spoIIIAE S stage III sporulation protein AE
GLFLGHEG_02124 2.5e-41 spoIIIAD S Stage III sporulation protein AD
GLFLGHEG_02125 7.6e-29 spoIIIAC S stage III sporulation protein AC
GLFLGHEG_02126 1.7e-85 spoIIIAB S Stage III sporulation protein
GLFLGHEG_02127 4.2e-172 spoIIIAA S stage III sporulation protein AA
GLFLGHEG_02128 1.8e-36 yqhV S Protein of unknown function (DUF2619)
GLFLGHEG_02129 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GLFLGHEG_02130 1.1e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
GLFLGHEG_02131 3.7e-88 yqhR S Conserved membrane protein YqhR
GLFLGHEG_02132 1e-173 yqhQ S Protein of unknown function (DUF1385)
GLFLGHEG_02133 3.4e-62 yqhP
GLFLGHEG_02134 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
GLFLGHEG_02135 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
GLFLGHEG_02136 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
GLFLGHEG_02137 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
GLFLGHEG_02138 1.5e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GLFLGHEG_02139 1.9e-250 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GLFLGHEG_02140 2.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
GLFLGHEG_02141 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
GLFLGHEG_02142 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
GLFLGHEG_02143 3.4e-22 sinI S Anti-repressor SinI
GLFLGHEG_02144 7.8e-55 sinR K transcriptional
GLFLGHEG_02145 3.3e-141 tasA S Cell division protein FtsN
GLFLGHEG_02146 1.3e-70 sipW 3.4.21.89 U Signal peptidase
GLFLGHEG_02147 3.8e-122 yqxM
GLFLGHEG_02148 8.3e-54 yqzG S Protein of unknown function (DUF3889)
GLFLGHEG_02149 2.3e-26 yqzE S YqzE-like protein
GLFLGHEG_02150 1.2e-61 S ComG operon protein 7
GLFLGHEG_02151 3e-66 comGF U Putative Competence protein ComGF
GLFLGHEG_02152 7.6e-20 comGE
GLFLGHEG_02153 6.2e-73 gspH NU Tfp pilus assembly protein FimT
GLFLGHEG_02154 8.9e-50 comGC U Required for transformation and DNA binding
GLFLGHEG_02155 4.1e-184 comGB NU COG1459 Type II secretory pathway, component PulF
GLFLGHEG_02156 7.8e-202 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GLFLGHEG_02157 9e-186 corA P Mg2 transporter protein
GLFLGHEG_02158 6.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
GLFLGHEG_02159 1.6e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GLFLGHEG_02161 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
GLFLGHEG_02162 3.1e-37 yqgY S Protein of unknown function (DUF2626)
GLFLGHEG_02163 1.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
GLFLGHEG_02164 5.4e-20 yqgW S Protein of unknown function (DUF2759)
GLFLGHEG_02165 6.9e-50 yqgV S Thiamine-binding protein
GLFLGHEG_02166 1.6e-199 yqgU
GLFLGHEG_02167 1.9e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
GLFLGHEG_02168 2.2e-179 glcK 2.7.1.2 G Glucokinase
GLFLGHEG_02169 1e-28 yqgQ S Protein conserved in bacteria
GLFLGHEG_02170 1.8e-213 nhaC C Na H antiporter
GLFLGHEG_02171 4e-07 yqgO
GLFLGHEG_02172 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GLFLGHEG_02173 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GLFLGHEG_02174 1.2e-50 yqzD
GLFLGHEG_02175 1.4e-72 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GLFLGHEG_02176 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GLFLGHEG_02177 3.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GLFLGHEG_02178 1.8e-156 pstA P Phosphate transport system permease
GLFLGHEG_02179 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
GLFLGHEG_02180 1.9e-156 pstS P Phosphate
GLFLGHEG_02181 0.0 pbpA 3.4.16.4 M penicillin-binding protein
GLFLGHEG_02182 4.5e-228 yqgE EGP Major facilitator superfamily
GLFLGHEG_02183 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
GLFLGHEG_02184 6e-77 yqgC S protein conserved in bacteria
GLFLGHEG_02185 8.7e-131 yqgB S Protein of unknown function (DUF1189)
GLFLGHEG_02186 3.7e-48 yqfZ M LysM domain
GLFLGHEG_02187 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GLFLGHEG_02188 2.3e-52 yqfX S membrane
GLFLGHEG_02189 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
GLFLGHEG_02190 2.9e-72 zur P Belongs to the Fur family
GLFLGHEG_02191 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
GLFLGHEG_02192 9.3e-37 yqfT S Protein of unknown function (DUF2624)
GLFLGHEG_02193 6.3e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GLFLGHEG_02194 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GLFLGHEG_02195 6.2e-51 yqfQ S YqfQ-like protein
GLFLGHEG_02196 4.9e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GLFLGHEG_02197 3.6e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GLFLGHEG_02198 2.2e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
GLFLGHEG_02199 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
GLFLGHEG_02200 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GLFLGHEG_02201 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GLFLGHEG_02202 6.1e-88 yaiI S Belongs to the UPF0178 family
GLFLGHEG_02203 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GLFLGHEG_02204 4.5e-112 ccpN K CBS domain
GLFLGHEG_02205 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GLFLGHEG_02206 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GLFLGHEG_02207 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
GLFLGHEG_02208 1.8e-16 S YqzL-like protein
GLFLGHEG_02209 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GLFLGHEG_02210 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GLFLGHEG_02211 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GLFLGHEG_02212 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GLFLGHEG_02213 0.0 yqfF S membrane-associated HD superfamily hydrolase
GLFLGHEG_02214 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
GLFLGHEG_02215 4.2e-217 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
GLFLGHEG_02216 9.3e-46 yqfC S sporulation protein YqfC
GLFLGHEG_02217 3.4e-55 yqfB
GLFLGHEG_02218 1.6e-121 yqfA S UPF0365 protein
GLFLGHEG_02219 2e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
GLFLGHEG_02220 1.2e-68 yqeY S Yqey-like protein
GLFLGHEG_02221 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GLFLGHEG_02222 1.3e-157 yqeW P COG1283 Na phosphate symporter
GLFLGHEG_02223 1.2e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
GLFLGHEG_02224 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GLFLGHEG_02225 1.6e-174 prmA J Methylates ribosomal protein L11
GLFLGHEG_02226 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GLFLGHEG_02227 0.0 dnaK O Heat shock 70 kDa protein
GLFLGHEG_02228 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GLFLGHEG_02229 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GLFLGHEG_02230 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
GLFLGHEG_02231 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GLFLGHEG_02232 3.8e-54 yqxA S Protein of unknown function (DUF3679)
GLFLGHEG_02233 1.4e-220 spoIIP M stage II sporulation protein P
GLFLGHEG_02234 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GLFLGHEG_02235 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
GLFLGHEG_02236 1.1e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
GLFLGHEG_02237 0.0 comEC S Competence protein ComEC
GLFLGHEG_02238 8e-105 comEB 3.5.4.12 F ComE operon protein 2
GLFLGHEG_02239 3.6e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
GLFLGHEG_02240 5e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GLFLGHEG_02241 2.2e-139 yqeM Q Methyltransferase
GLFLGHEG_02242 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GLFLGHEG_02243 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
GLFLGHEG_02244 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GLFLGHEG_02245 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
GLFLGHEG_02246 6e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GLFLGHEG_02247 1.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GLFLGHEG_02248 2.6e-94 yqeG S hydrolase of the HAD superfamily
GLFLGHEG_02250 7.7e-140 yqeF E GDSL-like Lipase/Acylhydrolase
GLFLGHEG_02251 4e-141 3.5.1.104 G Polysaccharide deacetylase
GLFLGHEG_02252 9.4e-107 yqeD S SNARE associated Golgi protein
GLFLGHEG_02253 7.4e-31 2.3.1.57 K Acetyltransferase (GNAT) domain
GLFLGHEG_02254 3.2e-215 EGP Major facilitator Superfamily
GLFLGHEG_02255 4e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GLFLGHEG_02256 1.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
GLFLGHEG_02257 4.4e-89 K Transcriptional regulator PadR-like family
GLFLGHEG_02258 3.1e-148 ydeE K AraC family transcriptional regulator
GLFLGHEG_02259 3.9e-21 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
GLFLGHEG_02260 1.5e-97 adk 2.7.4.3 F adenylate kinase activity
GLFLGHEG_02261 5.3e-219 tetL EGP Major facilitator Superfamily
GLFLGHEG_02262 1.3e-80 yyaR K Acetyltransferase (GNAT) domain
GLFLGHEG_02263 1.1e-92 yrdA S DinB family
GLFLGHEG_02265 9.1e-147 S hydrolase
GLFLGHEG_02266 1.2e-143 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
GLFLGHEG_02267 1.5e-127 glvR K Helix-turn-helix domain, rpiR family
GLFLGHEG_02268 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
GLFLGHEG_02269 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
GLFLGHEG_02270 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
GLFLGHEG_02271 3.1e-183 romA S Beta-lactamase superfamily domain
GLFLGHEG_02272 1.1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GLFLGHEG_02273 1.1e-164 yybE K Transcriptional regulator
GLFLGHEG_02274 2.5e-212 ynfM EGP Major facilitator Superfamily
GLFLGHEG_02275 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
GLFLGHEG_02276 9.1e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
GLFLGHEG_02277 3.9e-93 yrhH Q methyltransferase
GLFLGHEG_02279 8e-143 focA P Formate nitrite
GLFLGHEG_02280 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
GLFLGHEG_02281 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
GLFLGHEG_02282 1e-79 yrhD S Protein of unknown function (DUF1641)
GLFLGHEG_02283 1.8e-34 yrhC S YrhC-like protein
GLFLGHEG_02284 1.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GLFLGHEG_02285 4.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
GLFLGHEG_02286 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GLFLGHEG_02287 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
GLFLGHEG_02288 4.1e-27 yrzA S Protein of unknown function (DUF2536)
GLFLGHEG_02289 3.4e-68 yrrS S Protein of unknown function (DUF1510)
GLFLGHEG_02290 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
GLFLGHEG_02291 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GLFLGHEG_02292 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
GLFLGHEG_02293 1.6e-246 yegQ O COG0826 Collagenase and related proteases
GLFLGHEG_02294 1.7e-173 yegQ O Peptidase U32
GLFLGHEG_02295 2.1e-117 yrrM 2.1.1.104 S O-methyltransferase
GLFLGHEG_02296 9.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GLFLGHEG_02297 7.1e-46 yrzB S Belongs to the UPF0473 family
GLFLGHEG_02298 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GLFLGHEG_02299 8.5e-41 yrzL S Belongs to the UPF0297 family
GLFLGHEG_02300 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GLFLGHEG_02301 5.2e-166 yrrI S AI-2E family transporter
GLFLGHEG_02302 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GLFLGHEG_02303 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
GLFLGHEG_02304 1.2e-109 gluC P ABC transporter
GLFLGHEG_02305 4.4e-107 glnP P ABC transporter
GLFLGHEG_02306 2.1e-08 S Protein of unknown function (DUF3918)
GLFLGHEG_02307 2.9e-30 yrzR
GLFLGHEG_02308 1.8e-83 yrrD S protein conserved in bacteria
GLFLGHEG_02309 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GLFLGHEG_02310 1.7e-18 S COG0457 FOG TPR repeat
GLFLGHEG_02311 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GLFLGHEG_02312 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
GLFLGHEG_02313 7.8e-64 cymR K Transcriptional regulator
GLFLGHEG_02314 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
GLFLGHEG_02315 9.6e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
GLFLGHEG_02316 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GLFLGHEG_02317 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
GLFLGHEG_02320 3.8e-274 lytH 3.5.1.28 M COG3103 SH3 domain protein
GLFLGHEG_02321 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GLFLGHEG_02322 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GLFLGHEG_02323 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GLFLGHEG_02324 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
GLFLGHEG_02325 1.7e-46 yrvD S Lipopolysaccharide assembly protein A domain
GLFLGHEG_02326 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
GLFLGHEG_02327 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GLFLGHEG_02328 1.3e-50 yrzD S Post-transcriptional regulator
GLFLGHEG_02329 5e-32 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GLFLGHEG_02330 1.2e-228 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GLFLGHEG_02331 3.6e-109 yrbG S membrane
GLFLGHEG_02332 3.1e-60 yrzE S Protein of unknown function (DUF3792)
GLFLGHEG_02333 2.5e-37 yajC U Preprotein translocase subunit YajC
GLFLGHEG_02334 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GLFLGHEG_02335 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GLFLGHEG_02336 1.6e-20 yrzS S Protein of unknown function (DUF2905)
GLFLGHEG_02337 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GLFLGHEG_02338 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GLFLGHEG_02339 4.8e-93 bofC S BofC C-terminal domain
GLFLGHEG_02341 2.7e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GLFLGHEG_02342 1e-146 safA M spore coat assembly protein SafA
GLFLGHEG_02343 8.2e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GLFLGHEG_02344 7.4e-155 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
GLFLGHEG_02345 4.5e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
GLFLGHEG_02346 1.7e-223 nifS 2.8.1.7 E Cysteine desulfurase
GLFLGHEG_02347 1.1e-95 niaR S small molecule binding protein (contains 3H domain)
GLFLGHEG_02348 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
GLFLGHEG_02349 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
GLFLGHEG_02350 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GLFLGHEG_02351 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
GLFLGHEG_02352 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GLFLGHEG_02353 3.2e-56 ysxB J ribosomal protein
GLFLGHEG_02354 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
GLFLGHEG_02355 1.2e-160 spoIVFB S Stage IV sporulation protein
GLFLGHEG_02356 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
GLFLGHEG_02357 2.3e-142 minD D Belongs to the ParA family
GLFLGHEG_02358 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GLFLGHEG_02359 1.4e-84 mreD M shape-determining protein
GLFLGHEG_02360 1.2e-157 mreC M Involved in formation and maintenance of cell shape
GLFLGHEG_02361 4e-184 mreB D Rod shape-determining protein MreB
GLFLGHEG_02362 1.8e-127 radC E Belongs to the UPF0758 family
GLFLGHEG_02363 1.2e-100 maf D septum formation protein Maf
GLFLGHEG_02364 6.3e-137 spoIIB S Sporulation related domain
GLFLGHEG_02365 2.3e-131 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
GLFLGHEG_02366 3.9e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GLFLGHEG_02367 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GLFLGHEG_02368 2.1e-25
GLFLGHEG_02369 1.2e-196 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GLFLGHEG_02370 7e-222 spoVID M stage VI sporulation protein D
GLFLGHEG_02371 3.6e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
GLFLGHEG_02372 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
GLFLGHEG_02373 1e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
GLFLGHEG_02374 2.1e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GLFLGHEG_02375 3.6e-146 hemX O cytochrome C
GLFLGHEG_02376 2.4e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GLFLGHEG_02377 3.8e-87 ysxD
GLFLGHEG_02378 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
GLFLGHEG_02379 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GLFLGHEG_02380 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
GLFLGHEG_02381 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GLFLGHEG_02382 1.7e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GLFLGHEG_02383 5.4e-189 ysoA H Tetratricopeptide repeat
GLFLGHEG_02384 1.8e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GLFLGHEG_02385 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GLFLGHEG_02386 8.2e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GLFLGHEG_02387 3.5e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GLFLGHEG_02388 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GLFLGHEG_02389 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
GLFLGHEG_02390 0.0 ilvB 2.2.1.6 E Acetolactate synthase
GLFLGHEG_02395 1.5e-91 ysnB S Phosphoesterase
GLFLGHEG_02396 2.5e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GLFLGHEG_02397 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GLFLGHEG_02398 2.4e-198 gerM S COG5401 Spore germination protein
GLFLGHEG_02399 7.8e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GLFLGHEG_02400 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
GLFLGHEG_02401 2e-30 gerE K Transcriptional regulator
GLFLGHEG_02402 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
GLFLGHEG_02403 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
GLFLGHEG_02404 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
GLFLGHEG_02405 4.8e-108 sdhC C succinate dehydrogenase
GLFLGHEG_02406 7.7e-79 yslB S Protein of unknown function (DUF2507)
GLFLGHEG_02407 4.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
GLFLGHEG_02408 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GLFLGHEG_02409 2.5e-52 trxA O Belongs to the thioredoxin family
GLFLGHEG_02410 5.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
GLFLGHEG_02411 9.3e-178 etfA C Electron transfer flavoprotein
GLFLGHEG_02412 2e-138 etfB C Electron transfer flavoprotein
GLFLGHEG_02413 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
GLFLGHEG_02414 9.2e-104 fadR K Transcriptional regulator
GLFLGHEG_02415 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GLFLGHEG_02416 8.2e-125 ywbB S Protein of unknown function (DUF2711)
GLFLGHEG_02417 4.7e-67 yshE S membrane
GLFLGHEG_02418 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GLFLGHEG_02419 0.0 polX L COG1796 DNA polymerase IV (family X)
GLFLGHEG_02420 3.6e-83 cvpA S membrane protein, required for colicin V production
GLFLGHEG_02421 7.7e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GLFLGHEG_02422 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GLFLGHEG_02423 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GLFLGHEG_02424 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GLFLGHEG_02425 7e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GLFLGHEG_02426 2e-32 sspI S Belongs to the SspI family
GLFLGHEG_02427 4.9e-204 ysfB KT regulator
GLFLGHEG_02428 9.1e-259 glcD 1.1.3.15 C FAD binding domain
GLFLGHEG_02429 9.8e-255 glcF C Glycolate oxidase
GLFLGHEG_02430 0.0 cstA T Carbon starvation protein
GLFLGHEG_02431 3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
GLFLGHEG_02432 1.2e-144 araQ G transport system permease
GLFLGHEG_02433 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
GLFLGHEG_02434 5.2e-253 araN G carbohydrate transport
GLFLGHEG_02435 1.5e-225 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
GLFLGHEG_02436 4.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
GLFLGHEG_02437 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
GLFLGHEG_02438 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
GLFLGHEG_02439 8.1e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
GLFLGHEG_02440 5.2e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
GLFLGHEG_02441 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
GLFLGHEG_02442 9.2e-68 ysdB S Sigma-w pathway protein YsdB
GLFLGHEG_02443 7e-43 ysdA S Membrane
GLFLGHEG_02444 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GLFLGHEG_02445 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GLFLGHEG_02446 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GLFLGHEG_02447 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GLFLGHEG_02448 3.1e-40 lrgA S effector of murein hydrolase LrgA
GLFLGHEG_02449 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
GLFLGHEG_02450 0.0 lytS 2.7.13.3 T Histidine kinase
GLFLGHEG_02451 7.9e-151 ysaA S HAD-hyrolase-like
GLFLGHEG_02452 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GLFLGHEG_02453 6.7e-153 ytxC S YtxC-like family
GLFLGHEG_02454 2.7e-109 ytxB S SNARE associated Golgi protein
GLFLGHEG_02455 4.3e-172 dnaI L Primosomal protein DnaI
GLFLGHEG_02456 4.2e-256 dnaB L Membrane attachment protein
GLFLGHEG_02457 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GLFLGHEG_02458 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GLFLGHEG_02459 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GLFLGHEG_02460 2e-67 ytcD K Transcriptional regulator
GLFLGHEG_02461 1.4e-204 ytbD EGP Major facilitator Superfamily
GLFLGHEG_02462 1.5e-160 ytbE S reductase
GLFLGHEG_02463 2.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GLFLGHEG_02464 2.1e-106 ytaF P Probably functions as a manganese efflux pump
GLFLGHEG_02465 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GLFLGHEG_02466 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GLFLGHEG_02467 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
GLFLGHEG_02468 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GLFLGHEG_02469 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
GLFLGHEG_02470 3.1e-242 icd 1.1.1.42 C isocitrate
GLFLGHEG_02471 6.2e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
GLFLGHEG_02472 8.6e-48
GLFLGHEG_02473 2.5e-47 yjdF S Protein of unknown function (DUF2992)
GLFLGHEG_02474 1.5e-72 yeaL S membrane
GLFLGHEG_02475 3.6e-194 ytvI S sporulation integral membrane protein YtvI
GLFLGHEG_02476 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
GLFLGHEG_02477 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GLFLGHEG_02478 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GLFLGHEG_02479 1.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GLFLGHEG_02480 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GLFLGHEG_02481 1.7e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
GLFLGHEG_02482 0.0 dnaE 2.7.7.7 L DNA polymerase
GLFLGHEG_02483 3.2e-56 ytrH S Sporulation protein YtrH
GLFLGHEG_02484 5.1e-87 ytrI
GLFLGHEG_02485 4.4e-23
GLFLGHEG_02486 4.6e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
GLFLGHEG_02487 1.5e-46 ytpI S YtpI-like protein
GLFLGHEG_02488 4.1e-237 ytoI K transcriptional regulator containing CBS domains
GLFLGHEG_02489 2.5e-129 ytkL S Belongs to the UPF0173 family
GLFLGHEG_02490 4.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GLFLGHEG_02492 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
GLFLGHEG_02493 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GLFLGHEG_02494 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
GLFLGHEG_02495 7.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GLFLGHEG_02496 2.8e-182 ytxK 2.1.1.72 L DNA methylase
GLFLGHEG_02497 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GLFLGHEG_02498 1.5e-63 ytfJ S Sporulation protein YtfJ
GLFLGHEG_02499 3.8e-109 ytfI S Protein of unknown function (DUF2953)
GLFLGHEG_02500 4.5e-88 yteJ S RDD family
GLFLGHEG_02501 7.1e-181 sppA OU signal peptide peptidase SppA
GLFLGHEG_02502 5.7e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GLFLGHEG_02503 0.0 ytcJ S amidohydrolase
GLFLGHEG_02504 8.5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GLFLGHEG_02505 3.9e-31 sspB S spore protein
GLFLGHEG_02506 7.3e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GLFLGHEG_02507 3.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
GLFLGHEG_02508 6.9e-240 braB E Component of the transport system for branched-chain amino acids
GLFLGHEG_02509 1.2e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GLFLGHEG_02510 4.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
GLFLGHEG_02511 5e-108 yttP K Transcriptional regulator
GLFLGHEG_02512 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
GLFLGHEG_02513 4.7e-281 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
GLFLGHEG_02514 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GLFLGHEG_02515 3.7e-257 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
GLFLGHEG_02516 7.3e-64 yokH G SMI1 / KNR4 family
GLFLGHEG_02519 1.1e-58 UW Hep Hag repeat protein
GLFLGHEG_02520 2e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GLFLGHEG_02521 7.3e-09
GLFLGHEG_02522 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
GLFLGHEG_02524 1.3e-139 E GDSL-like Lipase/Acylhydrolase family
GLFLGHEG_02525 1.1e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GLFLGHEG_02526 4.4e-149 K Transcriptional regulator
GLFLGHEG_02527 5.2e-125 azlC E AzlC protein
GLFLGHEG_02528 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
GLFLGHEG_02529 7.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GLFLGHEG_02530 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GLFLGHEG_02531 8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
GLFLGHEG_02532 7.1e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
GLFLGHEG_02533 2.3e-231 acuC BQ histone deacetylase
GLFLGHEG_02534 2e-118 motS N Flagellar motor protein
GLFLGHEG_02535 5.1e-145 motA N flagellar motor
GLFLGHEG_02536 1.4e-181 ccpA K catabolite control protein A
GLFLGHEG_02537 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
GLFLGHEG_02538 2.9e-43 ytxJ O Protein of unknown function (DUF2847)
GLFLGHEG_02539 1.7e-16 ytxH S COG4980 Gas vesicle protein
GLFLGHEG_02540 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GLFLGHEG_02541 2.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GLFLGHEG_02542 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
GLFLGHEG_02543 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GLFLGHEG_02544 1.4e-147 ytpQ S Belongs to the UPF0354 family
GLFLGHEG_02545 2.7e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GLFLGHEG_02546 1.1e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
GLFLGHEG_02547 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
GLFLGHEG_02548 1.7e-51 ytzB S small secreted protein
GLFLGHEG_02549 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
GLFLGHEG_02550 1.5e-163 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
GLFLGHEG_02551 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GLFLGHEG_02552 3.5e-45 ytzH S YtzH-like protein
GLFLGHEG_02553 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
GLFLGHEG_02554 1.4e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
GLFLGHEG_02555 2.1e-166 ytlQ
GLFLGHEG_02556 9.8e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GLFLGHEG_02557 5e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GLFLGHEG_02558 5.1e-270 pepV 3.5.1.18 E Dipeptidase
GLFLGHEG_02559 4.1e-229 pbuO S permease
GLFLGHEG_02560 1.1e-217 ythQ U Bacterial ABC transporter protein EcsB
GLFLGHEG_02561 4.9e-128 ythP V ABC transporter
GLFLGHEG_02562 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
GLFLGHEG_02563 6.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GLFLGHEG_02564 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GLFLGHEG_02565 7.4e-236 ytfP S HI0933-like protein
GLFLGHEG_02566 4.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
GLFLGHEG_02567 9e-26 yteV S Sporulation protein Cse60
GLFLGHEG_02568 5.7e-186 msmR K Transcriptional regulator
GLFLGHEG_02569 7.5e-244 msmE G Bacterial extracellular solute-binding protein
GLFLGHEG_02570 2.6e-166 amyD G Binding-protein-dependent transport system inner membrane component
GLFLGHEG_02571 1.4e-142 amyC P ABC transporter (permease)
GLFLGHEG_02572 4.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
GLFLGHEG_02573 6e-85 M Acetyltransferase (GNAT) domain
GLFLGHEG_02574 5.6e-52 ytwF P Sulfurtransferase
GLFLGHEG_02575 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GLFLGHEG_02576 1.2e-52 ytvB S Protein of unknown function (DUF4257)
GLFLGHEG_02577 6.6e-140 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
GLFLGHEG_02578 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
GLFLGHEG_02579 1.1e-40 L transposase activity
GLFLGHEG_02580 7.3e-209 yttB EGP Major facilitator Superfamily
GLFLGHEG_02581 4.1e-130 ywaF S Integral membrane protein
GLFLGHEG_02582 0.0 bceB V ABC transporter (permease)
GLFLGHEG_02583 9.8e-135 bceA V ABC transporter, ATP-binding protein
GLFLGHEG_02584 9.2e-170 T PhoQ Sensor
GLFLGHEG_02585 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GLFLGHEG_02586 1.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
GLFLGHEG_02587 1.3e-125 ytrE V ABC transporter, ATP-binding protein
GLFLGHEG_02588 4.4e-159
GLFLGHEG_02589 2.9e-171 P ABC-2 family transporter protein
GLFLGHEG_02590 4e-168 S ABC-2 family transporter protein
GLFLGHEG_02591 4.2e-161 ytrB P abc transporter atp-binding protein
GLFLGHEG_02592 3.9e-66 ytrA K GntR family transcriptional regulator
GLFLGHEG_02594 6.2e-39 ytzC S Protein of unknown function (DUF2524)
GLFLGHEG_02595 3.6e-194 K helix_turn_helix, Arsenical Resistance Operon Repressor
GLFLGHEG_02596 4.3e-284 norB EGP COG0477 Permeases of the major facilitator superfamily
GLFLGHEG_02597 1.8e-189 yhcC S Fe-S oxidoreductase
GLFLGHEG_02598 1.9e-106 ytqB J Putative rRNA methylase
GLFLGHEG_02600 8.6e-145 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
GLFLGHEG_02601 9.9e-213 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
GLFLGHEG_02602 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
GLFLGHEG_02603 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GLFLGHEG_02604 1.9e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
GLFLGHEG_02605 0.0 asnB 6.3.5.4 E Asparagine synthase
GLFLGHEG_02606 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GLFLGHEG_02607 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GLFLGHEG_02608 1.6e-38 ytmB S Protein of unknown function (DUF2584)
GLFLGHEG_02609 6.1e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
GLFLGHEG_02610 3.3e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GLFLGHEG_02611 3.2e-144 ytlC P ABC transporter
GLFLGHEG_02612 5.8e-125 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GLFLGHEG_02613 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
GLFLGHEG_02614 1.7e-61 ytkC S Bacteriophage holin family
GLFLGHEG_02615 1.6e-76 dps P Belongs to the Dps family
GLFLGHEG_02617 1.8e-75 ytkA S YtkA-like
GLFLGHEG_02618 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GLFLGHEG_02619 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
GLFLGHEG_02620 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
GLFLGHEG_02621 3e-40 rpmE2 J Ribosomal protein L31
GLFLGHEG_02622 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
GLFLGHEG_02623 5.9e-183 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
GLFLGHEG_02624 2.3e-24 S Domain of Unknown Function (DUF1540)
GLFLGHEG_02625 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
GLFLGHEG_02626 1.7e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GLFLGHEG_02627 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GLFLGHEG_02628 1.7e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
GLFLGHEG_02629 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GLFLGHEG_02630 2.3e-270 menF 5.4.4.2 HQ Isochorismate synthase
GLFLGHEG_02631 2e-132 dksA T COG1734 DnaK suppressor protein
GLFLGHEG_02632 4.5e-77 tspO T membrane
GLFLGHEG_02641 7.8e-08
GLFLGHEG_02642 1.3e-09
GLFLGHEG_02649 1.6e-08
GLFLGHEG_02654 3.4e-39 S COG NOG14552 non supervised orthologous group
GLFLGHEG_02656 3.3e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
GLFLGHEG_02657 4e-175 yuaG 3.4.21.72 S protein conserved in bacteria
GLFLGHEG_02658 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
GLFLGHEG_02659 1.8e-81 yuaE S DinB superfamily
GLFLGHEG_02660 2.5e-109 yuaD S MOSC domain
GLFLGHEG_02661 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
GLFLGHEG_02662 7.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
GLFLGHEG_02663 2.7e-97 yuaC K Belongs to the GbsR family
GLFLGHEG_02664 2.1e-94 yuaB
GLFLGHEG_02665 7.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
GLFLGHEG_02666 5.6e-147 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GLFLGHEG_02667 4.5e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GLFLGHEG_02668 1.9e-123 G Cupin
GLFLGHEG_02669 1.8e-53 yjcN
GLFLGHEG_02671 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GLFLGHEG_02672 9e-196 yubA S transporter activity
GLFLGHEG_02673 2.1e-185 ygjR S Oxidoreductase
GLFLGHEG_02674 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
GLFLGHEG_02675 5.3e-236 mcpA NT chemotaxis protein
GLFLGHEG_02676 3.2e-225 mcpA NT chemotaxis protein
GLFLGHEG_02677 6.6e-239 mcpA NT chemotaxis protein
GLFLGHEG_02678 9.9e-219 mcpA NT chemotaxis protein
GLFLGHEG_02679 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
GLFLGHEG_02680 4.8e-41
GLFLGHEG_02681 5e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
GLFLGHEG_02682 9.7e-76 yugU S Uncharacterised protein family UPF0047
GLFLGHEG_02683 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
GLFLGHEG_02684 8.7e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
GLFLGHEG_02685 8.3e-117 yugP S Zn-dependent protease
GLFLGHEG_02686 4.5e-18
GLFLGHEG_02687 1.1e-26 mstX S Membrane-integrating protein Mistic
GLFLGHEG_02688 7e-181 yugO P COG1226 Kef-type K transport systems
GLFLGHEG_02689 2.8e-72 yugN S YugN-like family
GLFLGHEG_02691 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
GLFLGHEG_02693 6.1e-97 S NADPH-dependent FMN reductase
GLFLGHEG_02694 7.1e-118 ycaC Q Isochorismatase family
GLFLGHEG_02695 2.1e-229 yugK C Dehydrogenase
GLFLGHEG_02696 1.7e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
GLFLGHEG_02697 1.8e-34 yuzA S Domain of unknown function (DUF378)
GLFLGHEG_02698 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
GLFLGHEG_02699 7.2e-209 yugH 2.6.1.1 E Aminotransferase
GLFLGHEG_02700 2e-83 alaR K Transcriptional regulator
GLFLGHEG_02701 1.1e-155 yugF I Hydrolase
GLFLGHEG_02702 1.4e-40 yugE S Domain of unknown function (DUF1871)
GLFLGHEG_02703 9.3e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GLFLGHEG_02704 3.6e-230 T PhoQ Sensor
GLFLGHEG_02705 5.9e-67 kapB G Kinase associated protein B
GLFLGHEG_02706 4.5e-118 kapD L the KinA pathway to sporulation
GLFLGHEG_02707 1.7e-179 yuxJ EGP Major facilitator Superfamily
GLFLGHEG_02708 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
GLFLGHEG_02709 2.2e-72 yuxK S protein conserved in bacteria
GLFLGHEG_02710 9.3e-74 yufK S Family of unknown function (DUF5366)
GLFLGHEG_02711 2.2e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GLFLGHEG_02712 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
GLFLGHEG_02713 4.1e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
GLFLGHEG_02714 6.1e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
GLFLGHEG_02715 1.1e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
GLFLGHEG_02716 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
GLFLGHEG_02717 1.8e-12
GLFLGHEG_02718 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GLFLGHEG_02719 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GLFLGHEG_02720 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GLFLGHEG_02721 3.2e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GLFLGHEG_02722 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GLFLGHEG_02723 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GLFLGHEG_02724 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
GLFLGHEG_02725 6.7e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
GLFLGHEG_02726 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GLFLGHEG_02727 2.3e-275 comP 2.7.13.3 T Histidine kinase
GLFLGHEG_02729 1.5e-97 comQ H Belongs to the FPP GGPP synthase family
GLFLGHEG_02731 8.9e-51 yuzC
GLFLGHEG_02732 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
GLFLGHEG_02733 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GLFLGHEG_02734 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
GLFLGHEG_02735 7.2e-68 yueI S Protein of unknown function (DUF1694)
GLFLGHEG_02736 2.8e-38 yueH S YueH-like protein
GLFLGHEG_02737 6.4e-34 yueG S Spore germination protein gerPA/gerPF
GLFLGHEG_02738 1.9e-187 yueF S transporter activity
GLFLGHEG_02739 1.6e-22 S Protein of unknown function (DUF2642)
GLFLGHEG_02740 3.7e-96 yueE S phosphohydrolase
GLFLGHEG_02741 7.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GLFLGHEG_02742 6.9e-78 yueC S Family of unknown function (DUF5383)
GLFLGHEG_02743 0.0 esaA S type VII secretion protein EsaA
GLFLGHEG_02744 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GLFLGHEG_02745 2.8e-206 essB S WXG100 protein secretion system (Wss), protein YukC
GLFLGHEG_02746 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
GLFLGHEG_02747 3.3e-46 esxA S Belongs to the WXG100 family
GLFLGHEG_02748 1.5e-228 yukF QT Transcriptional regulator
GLFLGHEG_02749 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
GLFLGHEG_02750 2.8e-133 yukJ S Uncharacterized conserved protein (DUF2278)
GLFLGHEG_02751 1.3e-34 mbtH S MbtH-like protein
GLFLGHEG_02752 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_02753 7e-175 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
GLFLGHEG_02754 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
GLFLGHEG_02755 5.6e-225 entC 5.4.4.2 HQ Isochorismate synthase
GLFLGHEG_02756 1.9e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GLFLGHEG_02757 3.6e-165 besA S Putative esterase
GLFLGHEG_02758 1.2e-119 yuiH S Oxidoreductase molybdopterin binding domain
GLFLGHEG_02759 1.1e-101 bioY S Biotin biosynthesis protein
GLFLGHEG_02760 1.2e-207 yuiF S antiporter
GLFLGHEG_02761 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GLFLGHEG_02762 1.2e-77 yuiD S protein conserved in bacteria
GLFLGHEG_02763 4.2e-118 yuiC S protein conserved in bacteria
GLFLGHEG_02764 9.9e-28 yuiB S Putative membrane protein
GLFLGHEG_02765 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
GLFLGHEG_02766 1.1e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
GLFLGHEG_02768 2.1e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GLFLGHEG_02769 4.8e-29
GLFLGHEG_02770 3.1e-71 CP Membrane
GLFLGHEG_02771 7.3e-124 V ABC transporter
GLFLGHEG_02773 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
GLFLGHEG_02775 6.7e-93 rimJ 2.3.1.128 J Alanine acetyltransferase
GLFLGHEG_02776 2.5e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
GLFLGHEG_02777 1.1e-62 erpA S Belongs to the HesB IscA family
GLFLGHEG_02778 5.7e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GLFLGHEG_02779 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GLFLGHEG_02780 2.4e-39 yuzB S Belongs to the UPF0349 family
GLFLGHEG_02781 1.9e-208 yutJ 1.6.99.3 C NADH dehydrogenase
GLFLGHEG_02782 3.3e-55 yuzD S protein conserved in bacteria
GLFLGHEG_02783 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
GLFLGHEG_02784 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
GLFLGHEG_02785 7.5e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GLFLGHEG_02786 4.4e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GLFLGHEG_02787 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
GLFLGHEG_02788 3.2e-197 yutH S Spore coat protein
GLFLGHEG_02789 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
GLFLGHEG_02790 7.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GLFLGHEG_02791 8.6e-75 yutE S Protein of unknown function DUF86
GLFLGHEG_02792 1.7e-47 yutD S protein conserved in bacteria
GLFLGHEG_02793 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GLFLGHEG_02794 6.4e-195 lytH M Peptidase, M23
GLFLGHEG_02795 8.7e-131 yunB S Sporulation protein YunB (Spo_YunB)
GLFLGHEG_02796 1.8e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
GLFLGHEG_02797 1.8e-145 yunE S membrane transporter protein
GLFLGHEG_02798 2.6e-168 yunF S Protein of unknown function DUF72
GLFLGHEG_02799 1.5e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
GLFLGHEG_02800 9.1e-264 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
GLFLGHEG_02801 3.1e-303 pucR QT COG2508 Regulator of polyketide synthase expression
GLFLGHEG_02804 1e-88 S Aspartate phosphatase response regulator
GLFLGHEG_02805 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
GLFLGHEG_02806 2.2e-54 L COG2963 Transposase and inactivated derivatives
GLFLGHEG_02808 9.8e-70
GLFLGHEG_02809 1.2e-211 blt EGP Major facilitator Superfamily
GLFLGHEG_02810 1.1e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
GLFLGHEG_02811 1.3e-237 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GLFLGHEG_02812 4.1e-169 bsn L Ribonuclease
GLFLGHEG_02813 4.1e-206 msmX P Belongs to the ABC transporter superfamily
GLFLGHEG_02814 1e-133 yurK K UTRA
GLFLGHEG_02815 1e-159 yurL 2.7.1.218 G pfkB family carbohydrate kinase
GLFLGHEG_02816 6.9e-164 yurM P COG0395 ABC-type sugar transport system, permease component
GLFLGHEG_02817 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
GLFLGHEG_02818 4e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
GLFLGHEG_02819 7.9e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
GLFLGHEG_02820 8.6e-165 K helix_turn_helix, mercury resistance
GLFLGHEG_02821 3e-14
GLFLGHEG_02822 2.6e-76
GLFLGHEG_02823 2.7e-22 S Sporulation delaying protein SdpA
GLFLGHEG_02825 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
GLFLGHEG_02826 2.5e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
GLFLGHEG_02827 1.4e-122 Q ubiE/COQ5 methyltransferase family
GLFLGHEG_02828 1.7e-81 yncE S Protein of unknown function (DUF2691)
GLFLGHEG_02829 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
GLFLGHEG_02830 3e-270 sufB O FeS cluster assembly
GLFLGHEG_02831 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
GLFLGHEG_02832 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GLFLGHEG_02833 1.2e-244 sufD O assembly protein SufD
GLFLGHEG_02834 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GLFLGHEG_02835 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GLFLGHEG_02836 1.5e-144 metQ P Belongs to the NlpA lipoprotein family
GLFLGHEG_02837 4.4e-94 metI P COG2011 ABC-type metal ion transport system, permease component
GLFLGHEG_02838 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GLFLGHEG_02839 5e-57 yusD S SCP-2 sterol transfer family
GLFLGHEG_02840 1.6e-54 yusE CO Thioredoxin
GLFLGHEG_02841 3.7e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
GLFLGHEG_02842 3.7e-40 yusG S Protein of unknown function (DUF2553)
GLFLGHEG_02843 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
GLFLGHEG_02844 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
GLFLGHEG_02845 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
GLFLGHEG_02846 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
GLFLGHEG_02847 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
GLFLGHEG_02848 1.7e-165 fadM E Proline dehydrogenase
GLFLGHEG_02849 1.8e-210 yusP P Major facilitator superfamily
GLFLGHEG_02850 3.9e-43
GLFLGHEG_02851 1.1e-53 yusN M Coat F domain
GLFLGHEG_02852 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
GLFLGHEG_02853 8.1e-288 yusP P Major facilitator superfamily
GLFLGHEG_02854 4.8e-157 ywbI2 K Transcriptional regulator
GLFLGHEG_02855 5.9e-140 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
GLFLGHEG_02856 1.4e-187 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GLFLGHEG_02857 3.3e-39 yusU S Protein of unknown function (DUF2573)
GLFLGHEG_02858 1.4e-150 yusV 3.6.3.34 HP ABC transporter
GLFLGHEG_02859 1.9e-45 S YusW-like protein
GLFLGHEG_02860 0.0 pepF2 E COG1164 Oligoendopeptidase F
GLFLGHEG_02861 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GLFLGHEG_02862 1.6e-79 dps P Belongs to the Dps family
GLFLGHEG_02863 8.3e-241 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GLFLGHEG_02864 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GLFLGHEG_02865 3.9e-251 cssS 2.7.13.3 T PhoQ Sensor
GLFLGHEG_02866 3.4e-24
GLFLGHEG_02867 2.7e-158 yuxN K Transcriptional regulator
GLFLGHEG_02868 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GLFLGHEG_02869 6.6e-24 S Protein of unknown function (DUF3970)
GLFLGHEG_02870 4.9e-260 gerAA EG Spore germination protein
GLFLGHEG_02871 2e-184 gerAB E Spore germination protein
GLFLGHEG_02872 9.6e-203 gerAC S Spore germination B3/ GerAC like, C-terminal
GLFLGHEG_02873 3.3e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GLFLGHEG_02874 2.3e-193 vraS 2.7.13.3 T Histidine kinase
GLFLGHEG_02875 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
GLFLGHEG_02876 2.3e-127 liaG S Putative adhesin
GLFLGHEG_02877 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
GLFLGHEG_02878 3.3e-46 liaI S membrane
GLFLGHEG_02879 7.5e-228 yvqJ EGP Major facilitator Superfamily
GLFLGHEG_02880 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
GLFLGHEG_02881 1.1e-223 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
GLFLGHEG_02882 3.3e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLFLGHEG_02883 9.3e-167 yvrC P ABC transporter substrate-binding protein
GLFLGHEG_02884 1.2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GLFLGHEG_02885 3.8e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
GLFLGHEG_02886 0.0 T PhoQ Sensor
GLFLGHEG_02887 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GLFLGHEG_02888 7.3e-36
GLFLGHEG_02889 2.2e-102 yvrI K RNA polymerase
GLFLGHEG_02890 1.6e-15 S YvrJ protein family
GLFLGHEG_02891 1.2e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
GLFLGHEG_02892 1.1e-66 yvrL S Regulatory protein YrvL
GLFLGHEG_02893 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
GLFLGHEG_02894 1.2e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLFLGHEG_02895 2.1e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLFLGHEG_02896 4e-178 fhuD P ABC transporter
GLFLGHEG_02897 1.8e-235 yvsH E Arginine ornithine antiporter
GLFLGHEG_02898 3.6e-14 S Small spore protein J (Spore_SspJ)
GLFLGHEG_02899 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
GLFLGHEG_02900 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GLFLGHEG_02901 5.9e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
GLFLGHEG_02902 1.2e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
GLFLGHEG_02903 2.3e-94 modB P COG4149 ABC-type molybdate transport system, permease component
GLFLGHEG_02904 2e-112 yfiK K Regulator
GLFLGHEG_02905 6.6e-180 T Histidine kinase
GLFLGHEG_02906 5.6e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
GLFLGHEG_02907 6.1e-194 yfiM V ABC-2 type transporter
GLFLGHEG_02908 3e-199 yfiN V COG0842 ABC-type multidrug transport system, permease component
GLFLGHEG_02909 5e-156 yvgN S reductase
GLFLGHEG_02910 4.6e-85 yvgO
GLFLGHEG_02911 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
GLFLGHEG_02912 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
GLFLGHEG_02913 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GLFLGHEG_02914 0.0 helD 3.6.4.12 L DNA helicase
GLFLGHEG_02915 3.1e-99 yvgT S membrane
GLFLGHEG_02916 1.5e-141 S Metallo-peptidase family M12
GLFLGHEG_02917 2e-73 bdbC O Required for disulfide bond formation in some proteins
GLFLGHEG_02918 1.2e-102 bdbD O Thioredoxin
GLFLGHEG_02919 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
GLFLGHEG_02920 0.0 copA 3.6.3.54 P P-type ATPase
GLFLGHEG_02921 2.6e-29 copZ P Heavy-metal-associated domain
GLFLGHEG_02922 6.3e-48 csoR S transcriptional
GLFLGHEG_02923 4e-195 yvaA 1.1.1.371 S Oxidoreductase
GLFLGHEG_02924 2.1e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GLFLGHEG_02925 5.7e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLFLGHEG_02926 2.1e-45 ytnI O COG0695 Glutaredoxin and related proteins
GLFLGHEG_02927 6.4e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLFLGHEG_02928 9.5e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GLFLGHEG_02929 2.9e-120 tcyM U Binding-protein-dependent transport system inner membrane component
GLFLGHEG_02930 2.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
GLFLGHEG_02931 1.9e-147 tcyK M Bacterial periplasmic substrate-binding proteins
GLFLGHEG_02932 3.5e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
GLFLGHEG_02933 6.6e-101 ytmI K Acetyltransferase (GNAT) domain
GLFLGHEG_02934 4.7e-160 ytlI K LysR substrate binding domain
GLFLGHEG_02935 7.7e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GLFLGHEG_02936 4e-50 yrdF K ribonuclease inhibitor
GLFLGHEG_02938 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GLFLGHEG_02939 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GLFLGHEG_02940 3.7e-142 est 3.1.1.1 S Carboxylesterase
GLFLGHEG_02941 4.8e-24 secG U Preprotein translocase subunit SecG
GLFLGHEG_02942 6e-35 yvzC K Transcriptional
GLFLGHEG_02943 1e-69 K transcriptional
GLFLGHEG_02944 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
GLFLGHEG_02945 8.8e-53 yodB K transcriptional
GLFLGHEG_02946 1.2e-258 T His Kinase A (phosphoacceptor) domain
GLFLGHEG_02947 2.6e-123 K Transcriptional regulatory protein, C terminal
GLFLGHEG_02948 3.3e-138 mutG S ABC-2 family transporter protein
GLFLGHEG_02949 1.1e-122 spaE S ABC-2 family transporter protein
GLFLGHEG_02950 1.2e-126 mutF V ABC transporter, ATP-binding protein
GLFLGHEG_02951 2.3e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
GLFLGHEG_02952 8.5e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GLFLGHEG_02953 1.6e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
GLFLGHEG_02954 1.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GLFLGHEG_02955 4.3e-76 yvbF K Belongs to the GbsR family
GLFLGHEG_02956 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
GLFLGHEG_02957 3.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GLFLGHEG_02958 5.9e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
GLFLGHEG_02959 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GLFLGHEG_02960 1.9e-98 yvbF K Belongs to the GbsR family
GLFLGHEG_02961 5.2e-105 yvbG U UPF0056 membrane protein
GLFLGHEG_02962 4.5e-121 exoY M Membrane
GLFLGHEG_02963 0.0 tcaA S response to antibiotic
GLFLGHEG_02964 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
GLFLGHEG_02965 8.6e-213 EGP Major facilitator Superfamily
GLFLGHEG_02966 9.4e-180
GLFLGHEG_02967 4.4e-126 S GlcNAc-PI de-N-acetylase
GLFLGHEG_02968 2.5e-143 C WbqC-like protein family
GLFLGHEG_02969 2.6e-150 M Protein involved in cellulose biosynthesis
GLFLGHEG_02970 1.8e-234 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GLFLGHEG_02971 2.8e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
GLFLGHEG_02972 4.8e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
GLFLGHEG_02973 1.2e-255 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GLFLGHEG_02974 2.1e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
GLFLGHEG_02975 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GLFLGHEG_02976 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
GLFLGHEG_02977 1.5e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GLFLGHEG_02978 3.8e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GLFLGHEG_02979 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GLFLGHEG_02980 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GLFLGHEG_02982 7.4e-253 araE EGP Major facilitator Superfamily
GLFLGHEG_02983 2.2e-204 araR K transcriptional
GLFLGHEG_02984 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLFLGHEG_02986 1.4e-156 yvbU K Transcriptional regulator
GLFLGHEG_02987 7.7e-158 yvbV EG EamA-like transporter family
GLFLGHEG_02988 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
GLFLGHEG_02989 2.9e-259
GLFLGHEG_02990 1.4e-181 purR7 5.1.1.1 K Transcriptional regulator
GLFLGHEG_02991 6.9e-116 yyaS S Membrane
GLFLGHEG_02992 3.9e-167 3.1.3.104 S hydrolases of the HAD superfamily
GLFLGHEG_02993 8.5e-151 ybbH_1 K RpiR family transcriptional regulator
GLFLGHEG_02994 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
GLFLGHEG_02995 3.6e-225 gntP EG COG2610 H gluconate symporter and related permeases
GLFLGHEG_02996 8.2e-17 S leucine-zipper of insertion element IS481
GLFLGHEG_02999 3.7e-148 yobL S Bacterial EndoU nuclease
GLFLGHEG_03000 2.3e-31
GLFLGHEG_03001 1.8e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GLFLGHEG_03002 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
GLFLGHEG_03003 3.5e-134 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GLFLGHEG_03004 6.8e-223 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GLFLGHEG_03005 7.8e-121 yvfI K COG2186 Transcriptional regulators
GLFLGHEG_03006 4.2e-303 yvfH C L-lactate permease
GLFLGHEG_03007 2.6e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
GLFLGHEG_03008 2.7e-32 yvfG S YvfG protein
GLFLGHEG_03009 1.4e-189 yvfF GM Exopolysaccharide biosynthesis protein
GLFLGHEG_03010 5.7e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
GLFLGHEG_03011 1.2e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
GLFLGHEG_03012 3.4e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GLFLGHEG_03013 1.4e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GLFLGHEG_03014 3.4e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
GLFLGHEG_03015 1.9e-203 epsI GM pyruvyl transferase
GLFLGHEG_03016 1.1e-192 epsH GT2 S Glycosyltransferase like family 2
GLFLGHEG_03017 1e-204 epsG S EpsG family
GLFLGHEG_03018 5e-215 epsF GT4 M Glycosyl transferases group 1
GLFLGHEG_03019 5.2e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GLFLGHEG_03020 7.4e-219 epsD GT4 M Glycosyl transferase 4-like
GLFLGHEG_03021 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
GLFLGHEG_03022 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
GLFLGHEG_03023 1.9e-119 ywqC M biosynthesis protein
GLFLGHEG_03024 5.1e-78 slr K transcriptional
GLFLGHEG_03025 1.4e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
GLFLGHEG_03027 6.8e-98 ywjB H RibD C-terminal domain
GLFLGHEG_03028 8.3e-111 yyaS S Membrane
GLFLGHEG_03029 1.9e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GLFLGHEG_03030 5.5e-94 padC Q Phenolic acid decarboxylase
GLFLGHEG_03031 5.4e-13 S Protein of unknown function (DUF1433)
GLFLGHEG_03032 3.5e-24 S Protein of unknown function (DUF1433)
GLFLGHEG_03033 4.8e-13 S Protein of unknown function (DUF1433)
GLFLGHEG_03034 9.8e-20 S Protein of unknown function (DUF1433)
GLFLGHEG_03035 2.6e-211 I Pfam Lipase (class 3)
GLFLGHEG_03036 3.1e-34
GLFLGHEG_03038 4.4e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
GLFLGHEG_03039 2.8e-219 rafB P LacY proton/sugar symporter
GLFLGHEG_03040 1.3e-184 scrR K transcriptional
GLFLGHEG_03041 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GLFLGHEG_03042 6.7e-164 yraN K Transcriptional regulator
GLFLGHEG_03043 7.1e-214 yraM S PrpF protein
GLFLGHEG_03044 6.8e-251 EGP Sugar (and other) transporter
GLFLGHEG_03045 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
GLFLGHEG_03046 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
GLFLGHEG_03047 5.6e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
GLFLGHEG_03048 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
GLFLGHEG_03049 8.6e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GLFLGHEG_03050 1.6e-79 M Ribonuclease
GLFLGHEG_03051 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
GLFLGHEG_03052 4.7e-36 crh G Phosphocarrier protein Chr
GLFLGHEG_03053 3.1e-170 whiA K May be required for sporulation
GLFLGHEG_03054 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GLFLGHEG_03055 1.1e-166 rapZ S Displays ATPase and GTPase activities
GLFLGHEG_03056 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GLFLGHEG_03057 1.3e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GLFLGHEG_03058 5e-124 usp CBM50 M protein conserved in bacteria
GLFLGHEG_03059 5e-276 S COG0457 FOG TPR repeat
GLFLGHEG_03060 3.2e-192 sasA T Histidine kinase
GLFLGHEG_03061 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GLFLGHEG_03062 0.0 msbA2 3.6.3.44 V ABC transporter
GLFLGHEG_03063 5.6e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
GLFLGHEG_03064 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GLFLGHEG_03065 7.6e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GLFLGHEG_03066 1.5e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GLFLGHEG_03067 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
GLFLGHEG_03068 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GLFLGHEG_03069 1.3e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GLFLGHEG_03070 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GLFLGHEG_03071 1.2e-137 yvpB NU protein conserved in bacteria
GLFLGHEG_03072 1.3e-77 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
GLFLGHEG_03073 2.4e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
GLFLGHEG_03074 2.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GLFLGHEG_03075 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GLFLGHEG_03076 3.9e-131 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GLFLGHEG_03077 9e-62 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GLFLGHEG_03078 2.8e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GLFLGHEG_03079 1.1e-133 yvoA K transcriptional
GLFLGHEG_03080 1.8e-104 yxaF K Transcriptional regulator
GLFLGHEG_03081 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
GLFLGHEG_03082 3.9e-41 yvlD S Membrane
GLFLGHEG_03083 9.6e-26 pspB KT PspC domain
GLFLGHEG_03084 3.2e-166 yvlB S Putative adhesin
GLFLGHEG_03085 6.1e-49 yvlA
GLFLGHEG_03086 2.5e-37 yvkN
GLFLGHEG_03087 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GLFLGHEG_03088 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GLFLGHEG_03089 7.6e-33 csbA S protein conserved in bacteria
GLFLGHEG_03090 0.0 yvkC 2.7.9.2 GT Phosphotransferase
GLFLGHEG_03091 2.4e-110 yvkB K Transcriptional regulator
GLFLGHEG_03092 3e-227 yvkA EGP Major facilitator Superfamily
GLFLGHEG_03093 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GLFLGHEG_03094 1.5e-55 swrA S Swarming motility protein
GLFLGHEG_03095 2.1e-255 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
GLFLGHEG_03096 6.3e-228 ywoF P Right handed beta helix region
GLFLGHEG_03097 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GLFLGHEG_03098 1e-122 ftsE D cell division ATP-binding protein FtsE
GLFLGHEG_03099 2.4e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
GLFLGHEG_03100 1.6e-149 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
GLFLGHEG_03101 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GLFLGHEG_03102 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GLFLGHEG_03103 4.8e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GLFLGHEG_03104 6.8e-68
GLFLGHEG_03105 9.1e-11 fliT S bacterial-type flagellum organization
GLFLGHEG_03106 3e-66 fliS N flagellar protein FliS
GLFLGHEG_03107 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GLFLGHEG_03108 2e-103 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GLFLGHEG_03109 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GLFLGHEG_03110 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GLFLGHEG_03111 4.4e-79 yviE
GLFLGHEG_03112 2.3e-162 flgL N Belongs to the bacterial flagellin family
GLFLGHEG_03113 2.8e-274 flgK N flagellar hook-associated protein
GLFLGHEG_03114 8.9e-81 flgN NOU FlgN protein
GLFLGHEG_03115 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
GLFLGHEG_03116 1.4e-74 yvyF S flagellar protein
GLFLGHEG_03117 9.1e-78 comFC S Phosphoribosyl transferase domain
GLFLGHEG_03118 1.5e-43 comFB S Late competence development protein ComFB
GLFLGHEG_03119 2.1e-260 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GLFLGHEG_03120 3.5e-157 degV S protein conserved in bacteria
GLFLGHEG_03121 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GLFLGHEG_03122 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
GLFLGHEG_03123 2.2e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
GLFLGHEG_03124 1.1e-172 yvhJ K Transcriptional regulator
GLFLGHEG_03125 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
GLFLGHEG_03126 5.2e-239 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
GLFLGHEG_03127 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
GLFLGHEG_03128 1.6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
GLFLGHEG_03129 2.9e-257 tuaE M Teichuronic acid biosynthesis protein
GLFLGHEG_03130 6.6e-251 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GLFLGHEG_03131 7.3e-225 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
GLFLGHEG_03132 1e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GLFLGHEG_03133 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GLFLGHEG_03134 9.3e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GLFLGHEG_03135 0.0 lytB 3.5.1.28 D Stage II sporulation protein
GLFLGHEG_03136 5.9e-49
GLFLGHEG_03137 1.8e-143 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
GLFLGHEG_03138 9.7e-211 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GLFLGHEG_03139 6.3e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GLFLGHEG_03140 2.6e-283 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GLFLGHEG_03141 1.7e-151 tagG GM Transport permease protein
GLFLGHEG_03142 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GLFLGHEG_03143 3.3e-294 M Glycosyltransferase like family 2
GLFLGHEG_03144 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
GLFLGHEG_03145 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GLFLGHEG_03146 4.2e-217 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GLFLGHEG_03147 5.9e-235 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GLFLGHEG_03148 4.8e-187 pmi 5.3.1.8 G mannose-6-phosphate isomerase
GLFLGHEG_03149 1.3e-265 gerBA EG Spore germination protein
GLFLGHEG_03150 6.4e-199 gerBB E Spore germination protein
GLFLGHEG_03151 3.2e-214 gerAC S Spore germination protein
GLFLGHEG_03152 1.2e-266 GT2,GT4 J Glycosyl transferase family 2
GLFLGHEG_03153 3.7e-249 ywtG EGP Major facilitator Superfamily
GLFLGHEG_03154 3.8e-179 ywtF K Transcriptional regulator
GLFLGHEG_03155 6.5e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
GLFLGHEG_03156 4.5e-36 yttA 2.7.13.3 S Pfam Transposase IS66
GLFLGHEG_03157 6.3e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GLFLGHEG_03158 1.3e-20 ywtC
GLFLGHEG_03159 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
GLFLGHEG_03160 2.3e-70 pgsC S biosynthesis protein
GLFLGHEG_03161 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
GLFLGHEG_03162 7.7e-184 gerKA EG Spore germination protein
GLFLGHEG_03163 2.8e-191 gerKB E Spore germination protein
GLFLGHEG_03164 2e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
GLFLGHEG_03165 1.1e-178 rbsR K transcriptional
GLFLGHEG_03166 1.1e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GLFLGHEG_03167 9.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GLFLGHEG_03168 6.4e-279 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
GLFLGHEG_03169 3.2e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
GLFLGHEG_03170 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
GLFLGHEG_03171 5.2e-90 batE T Sh3 type 3 domain protein
GLFLGHEG_03172 4.8e-96 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
GLFLGHEG_03173 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
GLFLGHEG_03174 1.2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GLFLGHEG_03175 9e-167 alsR K LysR substrate binding domain
GLFLGHEG_03177 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GLFLGHEG_03178 4.4e-126 ywrJ
GLFLGHEG_03179 1.9e-129 cotB
GLFLGHEG_03180 3.4e-112 cotH M Spore Coat
GLFLGHEG_03181 2.2e-09
GLFLGHEG_03182 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GLFLGHEG_03184 3e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
GLFLGHEG_03185 1.1e-83 ywrC K Transcriptional regulator
GLFLGHEG_03186 4.6e-103 ywrB P Chromate transporter
GLFLGHEG_03187 8.4e-88 ywrA P COG2059 Chromate transport protein ChrA
GLFLGHEG_03188 1.5e-97 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
GLFLGHEG_03189 1.1e-24
GLFLGHEG_03190 2.1e-258 ywqJ S Pre-toxin TG
GLFLGHEG_03191 4.3e-37 ywqI S Family of unknown function (DUF5344)
GLFLGHEG_03192 1.1e-21 S Domain of unknown function (DUF5082)
GLFLGHEG_03194 1.4e-152 ywqG S Domain of unknown function (DUF1963)
GLFLGHEG_03195 1.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GLFLGHEG_03196 8.4e-142 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
GLFLGHEG_03197 1.5e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
GLFLGHEG_03198 5.2e-112 ywqC M biosynthesis protein
GLFLGHEG_03199 1.3e-14
GLFLGHEG_03200 9.3e-308 ywqB S SWIM zinc finger
GLFLGHEG_03201 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
GLFLGHEG_03202 1.1e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
GLFLGHEG_03203 3.7e-137 glcR K DeoR C terminal sensor domain
GLFLGHEG_03204 3.7e-57 ssbB L Single-stranded DNA-binding protein
GLFLGHEG_03205 4e-62 ywpG
GLFLGHEG_03206 3.9e-69 ywpF S YwpF-like protein
GLFLGHEG_03207 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GLFLGHEG_03208 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GLFLGHEG_03209 2.9e-201 S aspartate phosphatase
GLFLGHEG_03210 3.3e-144 flhP N flagellar basal body
GLFLGHEG_03211 4.7e-127 flhO N flagellar basal body
GLFLGHEG_03212 2.7e-180 mbl D Rod shape-determining protein
GLFLGHEG_03213 1.8e-44 spoIIID K Stage III sporulation protein D
GLFLGHEG_03214 8.5e-72 ywoH K transcriptional
GLFLGHEG_03215 2.4e-212 ywoG EGP Major facilitator Superfamily
GLFLGHEG_03216 5e-276 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
GLFLGHEG_03217 2e-242 ywoD EGP Major facilitator superfamily
GLFLGHEG_03218 2.4e-101 phzA Q Isochorismatase family
GLFLGHEG_03219 2.5e-228 amt P Ammonium transporter
GLFLGHEG_03220 2e-58 nrgB K Belongs to the P(II) protein family
GLFLGHEG_03221 2.4e-209 ftsW D Belongs to the SEDS family
GLFLGHEG_03222 4.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
GLFLGHEG_03223 5.1e-72 ywnJ S VanZ like family
GLFLGHEG_03224 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
GLFLGHEG_03225 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
GLFLGHEG_03226 1.2e-10 ywnC S Family of unknown function (DUF5362)
GLFLGHEG_03227 1.6e-68 ywnF S Family of unknown function (DUF5392)
GLFLGHEG_03228 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GLFLGHEG_03229 1.7e-53 ywnC S Family of unknown function (DUF5362)
GLFLGHEG_03230 4.5e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
GLFLGHEG_03231 6.1e-67 ywnA K Transcriptional regulator
GLFLGHEG_03232 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GLFLGHEG_03233 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
GLFLGHEG_03234 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
GLFLGHEG_03235 6.5e-11 csbD K CsbD-like
GLFLGHEG_03236 2.1e-82 ywmF S Peptidase M50
GLFLGHEG_03237 2.8e-93 S response regulator aspartate phosphatase
GLFLGHEG_03238 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GLFLGHEG_03239 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GLFLGHEG_03241 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
GLFLGHEG_03242 2.7e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
GLFLGHEG_03243 4.3e-189 spoIID D Stage II sporulation protein D
GLFLGHEG_03244 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GLFLGHEG_03245 4.8e-134 ywmB S TATA-box binding
GLFLGHEG_03246 4.8e-32 ywzB S membrane
GLFLGHEG_03247 1.2e-90 ywmA
GLFLGHEG_03248 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GLFLGHEG_03249 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GLFLGHEG_03250 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GLFLGHEG_03251 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GLFLGHEG_03252 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GLFLGHEG_03253 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GLFLGHEG_03254 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GLFLGHEG_03255 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
GLFLGHEG_03256 2.1e-61 atpI S ATP synthase
GLFLGHEG_03257 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GLFLGHEG_03258 3e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GLFLGHEG_03259 5.9e-97 ywlG S Belongs to the UPF0340 family
GLFLGHEG_03260 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
GLFLGHEG_03261 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GLFLGHEG_03262 9e-85 mntP P Probably functions as a manganese efflux pump
GLFLGHEG_03263 1e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GLFLGHEG_03264 1e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
GLFLGHEG_03265 1.5e-118 spoIIR S stage II sporulation protein R
GLFLGHEG_03266 4e-60 ywlA S Uncharacterised protein family (UPF0715)
GLFLGHEG_03268 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GLFLGHEG_03269 3.3e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GLFLGHEG_03270 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GLFLGHEG_03271 1.1e-93 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
GLFLGHEG_03272 3.6e-158 ywkB S Membrane transport protein
GLFLGHEG_03273 0.0 sfcA 1.1.1.38 C malic enzyme
GLFLGHEG_03274 1.4e-104 tdk 2.7.1.21 F thymidine kinase
GLFLGHEG_03275 1.1e-32 rpmE J Binds the 23S rRNA
GLFLGHEG_03276 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GLFLGHEG_03277 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
GLFLGHEG_03278 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GLFLGHEG_03279 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GLFLGHEG_03280 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
GLFLGHEG_03281 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
GLFLGHEG_03282 1.7e-93 ywjG S Domain of unknown function (DUF2529)
GLFLGHEG_03283 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GLFLGHEG_03284 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GLFLGHEG_03285 0.0 fadF C COG0247 Fe-S oxidoreductase
GLFLGHEG_03286 3.5e-219 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
GLFLGHEG_03287 1.2e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
GLFLGHEG_03288 4.2e-43 ywjC
GLFLGHEG_03289 0.0 ywjA V ABC transporter
GLFLGHEG_03290 9.6e-302 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GLFLGHEG_03291 1.4e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GLFLGHEG_03292 4.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
GLFLGHEG_03293 1.8e-96 narJ 1.7.5.1 C nitrate reductase
GLFLGHEG_03294 1.8e-294 narH 1.7.5.1 C Nitrate reductase, beta
GLFLGHEG_03295 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GLFLGHEG_03296 4.5e-85 arfM T cyclic nucleotide binding
GLFLGHEG_03297 1.7e-139 ywiC S YwiC-like protein
GLFLGHEG_03298 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
GLFLGHEG_03299 5.8e-214 narK P COG2223 Nitrate nitrite transporter
GLFLGHEG_03300 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GLFLGHEG_03301 1.2e-73 ywiB S protein conserved in bacteria
GLFLGHEG_03303 1.1e-229 ywhL CO amine dehydrogenase activity
GLFLGHEG_03304 1.5e-221 ywhK CO amine dehydrogenase activity
GLFLGHEG_03305 1.4e-76 S aspartate phosphatase
GLFLGHEG_03307 2.6e-29 ydcG K sequence-specific DNA binding
GLFLGHEG_03308 5e-33
GLFLGHEG_03309 1.3e-27 S Domain of unknown function (DUF4177)
GLFLGHEG_03311 3.1e-76 CP Membrane
GLFLGHEG_03314 2.7e-168 speB 3.5.3.11 E Belongs to the arginase family
GLFLGHEG_03315 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GLFLGHEG_03316 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GLFLGHEG_03317 8.5e-83
GLFLGHEG_03318 1.4e-95 ywhD S YwhD family
GLFLGHEG_03319 1.2e-117 ywhC S Peptidase family M50
GLFLGHEG_03320 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
GLFLGHEG_03321 5.2e-69 ywhA K Transcriptional regulator
GLFLGHEG_03322 1.3e-246 yhdG_1 E C-terminus of AA_permease
GLFLGHEG_03323 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
GLFLGHEG_03324 7.9e-257 ywfO S COG1078 HD superfamily phosphohydrolases
GLFLGHEG_03325 6.9e-36 ywzC S Belongs to the UPF0741 family
GLFLGHEG_03326 6.6e-110 rsfA_1
GLFLGHEG_03327 4.1e-50 padR K PadR family transcriptional regulator
GLFLGHEG_03328 1.5e-92 S membrane
GLFLGHEG_03329 1.6e-166 V ABC transporter, ATP-binding protein
GLFLGHEG_03330 4.5e-169 yhcI S ABC transporter (permease)
GLFLGHEG_03333 1.4e-186
GLFLGHEG_03335 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
GLFLGHEG_03336 3e-162 cysL K Transcriptional regulator
GLFLGHEG_03337 1.1e-157 MA20_14895 S Conserved hypothetical protein 698
GLFLGHEG_03338 1.1e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
GLFLGHEG_03339 1.1e-146 ywfI C May function as heme-dependent peroxidase
GLFLGHEG_03340 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
GLFLGHEG_03341 1.9e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
GLFLGHEG_03342 4.7e-208 bacE EGP Major facilitator Superfamily
GLFLGHEG_03343 2.2e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
GLFLGHEG_03344 1.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GLFLGHEG_03345 3.4e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
GLFLGHEG_03346 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
GLFLGHEG_03347 4.1e-223 ywfA EGP Major facilitator Superfamily
GLFLGHEG_03348 1.1e-196 tcaB EGP Major facilitator Superfamily
GLFLGHEG_03349 1.4e-259 lysP E amino acid
GLFLGHEG_03350 0.0 rocB E arginine degradation protein
GLFLGHEG_03351 3.9e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
GLFLGHEG_03352 9.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
GLFLGHEG_03353 3.2e-59
GLFLGHEG_03354 5.5e-88 spsL 5.1.3.13 M Spore Coat
GLFLGHEG_03355 8.1e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GLFLGHEG_03356 9.3e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GLFLGHEG_03357 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GLFLGHEG_03358 9.9e-183 spsG M Spore Coat
GLFLGHEG_03359 1.1e-133 spsF M Spore Coat
GLFLGHEG_03360 2.9e-215 spsE 2.5.1.56 M acid synthase
GLFLGHEG_03361 1e-159 spsD 2.3.1.210 K Spore Coat
GLFLGHEG_03362 3.3e-222 spsC E Belongs to the DegT DnrJ EryC1 family
GLFLGHEG_03363 1.7e-276 spsB M Capsule polysaccharide biosynthesis protein
GLFLGHEG_03364 3.4e-143 spsA M Spore Coat
GLFLGHEG_03365 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
GLFLGHEG_03366 1.6e-45 ywdK S small membrane protein
GLFLGHEG_03367 3.7e-230 ywdJ F Xanthine uracil
GLFLGHEG_03368 4.7e-41 ywdI S Family of unknown function (DUF5327)
GLFLGHEG_03369 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GLFLGHEG_03370 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
GLFLGHEG_03372 7.6e-88 ywdD
GLFLGHEG_03373 6.3e-57 pex K Transcriptional regulator PadR-like family
GLFLGHEG_03374 1.3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GLFLGHEG_03375 9.7e-20 ywdA
GLFLGHEG_03376 9.5e-288 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
GLFLGHEG_03377 6.2e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GLFLGHEG_03378 8.3e-151 sacT K transcriptional antiterminator
GLFLGHEG_03380 0.0 vpr O Belongs to the peptidase S8 family
GLFLGHEG_03381 8.9e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLFLGHEG_03382 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
GLFLGHEG_03383 2.9e-213 rodA D Belongs to the SEDS family
GLFLGHEG_03384 1.5e-78 ysnE K acetyltransferase
GLFLGHEG_03385 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
GLFLGHEG_03386 5.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
GLFLGHEG_03387 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
GLFLGHEG_03388 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GLFLGHEG_03389 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
GLFLGHEG_03390 8.4e-27 ywzA S membrane
GLFLGHEG_03391 3.5e-296 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GLFLGHEG_03392 8.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GLFLGHEG_03393 3.5e-62 gtcA S GtrA-like protein
GLFLGHEG_03394 4.3e-112 ywcC K Bacterial regulatory proteins, tetR family
GLFLGHEG_03396 4.3e-129 H Methionine biosynthesis protein MetW
GLFLGHEG_03397 6.3e-133 S Streptomycin biosynthesis protein StrF
GLFLGHEG_03398 1.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
GLFLGHEG_03399 1.1e-242 ywbN P Dyp-type peroxidase family protein
GLFLGHEG_03400 5.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GLFLGHEG_03401 4.3e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GLFLGHEG_03402 8.2e-152 ywbI K Transcriptional regulator
GLFLGHEG_03403 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
GLFLGHEG_03404 4.1e-108 ywbG M effector of murein hydrolase
GLFLGHEG_03405 1e-95 V ATPases associated with a variety of cellular activities
GLFLGHEG_03408 1.3e-105
GLFLGHEG_03410 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
GLFLGHEG_03411 2.2e-54 L COG2963 Transposase and inactivated derivatives
GLFLGHEG_03412 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
GLFLGHEG_03413 4.9e-142 mta K transcriptional
GLFLGHEG_03414 3.3e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
GLFLGHEG_03415 8.8e-223 ywbD 2.1.1.191 J Methyltransferase
GLFLGHEG_03416 9e-68 ywbC 4.4.1.5 E glyoxalase
GLFLGHEG_03417 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GLFLGHEG_03418 3.3e-266 epr 3.4.21.62 O Belongs to the peptidase S8 family
GLFLGHEG_03419 2.6e-163 gspA M General stress
GLFLGHEG_03420 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
GLFLGHEG_03421 1.7e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
GLFLGHEG_03422 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
GLFLGHEG_03423 5.5e-294 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_03424 3.7e-229 dltB M membrane protein involved in D-alanine export
GLFLGHEG_03425 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GLFLGHEG_03426 1.8e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GLFLGHEG_03427 1.3e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
GLFLGHEG_03428 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GLFLGHEG_03429 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
GLFLGHEG_03430 5.3e-248 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GLFLGHEG_03431 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
GLFLGHEG_03432 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
GLFLGHEG_03433 2.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
GLFLGHEG_03434 1.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLFLGHEG_03435 1.3e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLFLGHEG_03436 4e-167 cbrA3 P Periplasmic binding protein
GLFLGHEG_03437 4.5e-58 arsR K transcriptional
GLFLGHEG_03438 2.2e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GLFLGHEG_03439 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
GLFLGHEG_03440 9.1e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
GLFLGHEG_03441 3.2e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GLFLGHEG_03442 1.5e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GLFLGHEG_03443 1.9e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
GLFLGHEG_03444 3.3e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
GLFLGHEG_03445 4.2e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
GLFLGHEG_03446 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
GLFLGHEG_03447 2.2e-54 L COG2963 Transposase and inactivated derivatives
GLFLGHEG_03448 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
GLFLGHEG_03449 1.9e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
GLFLGHEG_03450 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
GLFLGHEG_03451 2e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GLFLGHEG_03452 1.3e-291 cydD V ATP-binding protein
GLFLGHEG_03453 2.4e-311 cydD V ATP-binding
GLFLGHEG_03454 5.7e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
GLFLGHEG_03455 1.2e-266 cydA 1.10.3.14 C oxidase, subunit
GLFLGHEG_03456 1.5e-215 cimH C COG3493 Na citrate symporter
GLFLGHEG_03457 7.1e-158 yxkH G Polysaccharide deacetylase
GLFLGHEG_03458 2.6e-205 msmK P Belongs to the ABC transporter superfamily
GLFLGHEG_03459 6.1e-168 lrp QT PucR C-terminal helix-turn-helix domain
GLFLGHEG_03460 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GLFLGHEG_03461 3.8e-87 yxkC S Domain of unknown function (DUF4352)
GLFLGHEG_03462 1.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GLFLGHEG_03463 4.7e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GLFLGHEG_03466 1.2e-69 yxjI S LURP-one-related
GLFLGHEG_03467 1.1e-217 yxjG 2.1.1.14 E Methionine synthase
GLFLGHEG_03468 2.2e-162 rlmA 2.1.1.187 Q Methyltransferase domain
GLFLGHEG_03469 4.6e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GLFLGHEG_03470 7.8e-75 T Domain of unknown function (DUF4163)
GLFLGHEG_03471 1.4e-50 yxiS
GLFLGHEG_03472 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
GLFLGHEG_03473 2.8e-222 citH C Citrate transporter
GLFLGHEG_03474 1.5e-143 exoK GH16 M licheninase activity
GLFLGHEG_03475 7.7e-149 licT K transcriptional antiterminator
GLFLGHEG_03476 2.9e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
GLFLGHEG_03477 3.4e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
GLFLGHEG_03480 4e-36 yxiG
GLFLGHEG_03481 5.9e-32
GLFLGHEG_03482 0.0 wapA M COG3209 Rhs family protein
GLFLGHEG_03483 1e-18 wapA M COG3209 Rhs family protein
GLFLGHEG_03484 1.3e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
GLFLGHEG_03485 1.2e-147 yxxF EG EamA-like transporter family
GLFLGHEG_03486 6.3e-73 yxiE T Belongs to the universal stress protein A family
GLFLGHEG_03487 2.7e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GLFLGHEG_03488 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GLFLGHEG_03489 0.0 L HKD family nuclease
GLFLGHEG_03490 1.4e-197 L HKD family nuclease
GLFLGHEG_03491 2.8e-64 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GLFLGHEG_03492 2.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
GLFLGHEG_03493 3.8e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
GLFLGHEG_03494 1.5e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
GLFLGHEG_03495 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GLFLGHEG_03496 8.8e-237 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
GLFLGHEG_03497 4.5e-177 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
GLFLGHEG_03498 2.9e-252 lysP E amino acid
GLFLGHEG_03499 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
GLFLGHEG_03500 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GLFLGHEG_03501 1.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GLFLGHEG_03502 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GLFLGHEG_03503 4e-150 yidA S hydrolases of the HAD superfamily
GLFLGHEG_03506 6.4e-13 yxeE
GLFLGHEG_03507 8.4e-23 yxeD
GLFLGHEG_03508 6e-35
GLFLGHEG_03509 3.9e-176 fhuD P Periplasmic binding protein
GLFLGHEG_03510 1.3e-57 yxeA S Protein of unknown function (DUF1093)
GLFLGHEG_03511 0.0 yxdM V ABC transporter (permease)
GLFLGHEG_03512 5.5e-141 yxdL V ABC transporter, ATP-binding protein
GLFLGHEG_03513 1.6e-174 T PhoQ Sensor
GLFLGHEG_03514 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GLFLGHEG_03515 1.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
GLFLGHEG_03516 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
GLFLGHEG_03517 1.1e-166 iolH G Xylose isomerase-like TIM barrel
GLFLGHEG_03518 5.6e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
GLFLGHEG_03519 3.9e-232 iolF EGP Major facilitator Superfamily
GLFLGHEG_03520 3.6e-176 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
GLFLGHEG_03521 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
GLFLGHEG_03522 4.4e-183 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
GLFLGHEG_03523 2.2e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
GLFLGHEG_03524 5.1e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GLFLGHEG_03525 6.8e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
GLFLGHEG_03526 4.9e-176 iolS C Aldo keto reductase
GLFLGHEG_03527 6.7e-246 csbC EGP Major facilitator Superfamily
GLFLGHEG_03528 0.0 htpG O Molecular chaperone. Has ATPase activity
GLFLGHEG_03530 3.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
GLFLGHEG_03531 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GLFLGHEG_03532 1.7e-199 desK 2.7.13.3 T Histidine kinase
GLFLGHEG_03533 2.6e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
GLFLGHEG_03534 2.1e-216 yxbF K Bacterial regulatory proteins, tetR family
GLFLGHEG_03535 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
GLFLGHEG_03536 1.2e-140 S PQQ-like domain
GLFLGHEG_03537 1.7e-59 S Family of unknown function (DUF5391)
GLFLGHEG_03538 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
GLFLGHEG_03539 2e-203 EGP Major facilitator Superfamily
GLFLGHEG_03540 7.6e-74 yxaI S membrane protein domain
GLFLGHEG_03541 2.4e-127 E Ring-cleavage extradiol dioxygenase
GLFLGHEG_03542 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
GLFLGHEG_03543 2.3e-287 ahpF O Alkyl hydroperoxide reductase
GLFLGHEG_03544 2.7e-230 XK27_00240 S Fic/DOC family
GLFLGHEG_03545 1.4e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
GLFLGHEG_03546 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
GLFLGHEG_03547 1.1e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
GLFLGHEG_03548 1.6e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
GLFLGHEG_03549 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
GLFLGHEG_03550 3.7e-95 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
GLFLGHEG_03551 7.2e-189 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GLFLGHEG_03552 6.1e-180 S Fusaric acid resistance protein-like
GLFLGHEG_03553 5.5e-247 L Uncharacterized conserved protein (DUF2075)
GLFLGHEG_03554 2.6e-115
GLFLGHEG_03555 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GLFLGHEG_03556 7.9e-08 S YyzF-like protein
GLFLGHEG_03558 2.9e-218 yycP
GLFLGHEG_03559 2.4e-133 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GLFLGHEG_03560 2.1e-185 C oxidoreductases (related to aryl-alcohol dehydrogenases)
GLFLGHEG_03561 3.7e-87 yycN 2.3.1.128 K Acetyltransferase
GLFLGHEG_03563 7.6e-200 S Histidine kinase
GLFLGHEG_03564 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
GLFLGHEG_03565 2.6e-258 rocE E amino acid
GLFLGHEG_03566 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
GLFLGHEG_03567 4.2e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
GLFLGHEG_03568 2.2e-42 sdpR K transcriptional
GLFLGHEG_03569 3.4e-261 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
GLFLGHEG_03570 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
GLFLGHEG_03571 5.7e-305 S ABC transporter
GLFLGHEG_03572 3.4e-198 S Major Facilitator Superfamily
GLFLGHEG_03573 1e-259
GLFLGHEG_03574 4.9e-190 2.7.7.73, 2.7.7.80 H ThiF family
GLFLGHEG_03575 1.1e-251 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
GLFLGHEG_03576 4.7e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GLFLGHEG_03577 1.3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GLFLGHEG_03578 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
GLFLGHEG_03579 6.4e-151 yycI S protein conserved in bacteria
GLFLGHEG_03580 1e-259 yycH S protein conserved in bacteria
GLFLGHEG_03581 0.0 vicK 2.7.13.3 T Histidine kinase
GLFLGHEG_03582 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GLFLGHEG_03587 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GLFLGHEG_03588 9.1e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GLFLGHEG_03589 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GLFLGHEG_03590 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
GLFLGHEG_03592 3.5e-17 yycC K YycC-like protein
GLFLGHEG_03593 4.6e-241 M Glycosyltransferase Family 4
GLFLGHEG_03594 5.1e-206 S Ecdysteroid kinase
GLFLGHEG_03595 7.7e-235 S Carbamoyl-phosphate synthase L chain, ATP binding domain
GLFLGHEG_03596 1.9e-242 M Glycosyltransferase Family 4
GLFLGHEG_03597 1.7e-122 S GlcNAc-PI de-N-acetylase
GLFLGHEG_03598 3.8e-122 KLT COG0515 Serine threonine protein kinase
GLFLGHEG_03599 1.4e-72 rplI J binds to the 23S rRNA
GLFLGHEG_03600 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GLFLGHEG_03601 1.6e-158 yybS S membrane
GLFLGHEG_03603 1.1e-83 cotF M Spore coat protein
GLFLGHEG_03604 8.2e-66 ydeP3 K Transcriptional regulator
GLFLGHEG_03605 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
GLFLGHEG_03606 4.4e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GLFLGHEG_03607 7.7e-274 sacB 2.4.1.10 GH68 M levansucrase activity
GLFLGHEG_03608 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
GLFLGHEG_03609 1.8e-116 K FCD domain
GLFLGHEG_03610 2.7e-75 dinB S PFAM DinB family protein
GLFLGHEG_03611 8.9e-162 G Major Facilitator Superfamily
GLFLGHEG_03612 8.4e-162 yfiE K LysR substrate binding domain
GLFLGHEG_03613 1.6e-100 E LysE type translocator
GLFLGHEG_03614 1.3e-55 ypaA S Protein of unknown function (DUF1304)
GLFLGHEG_03615 5.6e-115 drgA C nitroreductase
GLFLGHEG_03616 9.2e-69 ydgJ K Winged helix DNA-binding domain
GLFLGHEG_03617 9.3e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
GLFLGHEG_03618 2.5e-77 yybA 2.3.1.57 K transcriptional
GLFLGHEG_03619 3.5e-76 yjcF S Acetyltransferase (GNAT) domain
GLFLGHEG_03620 5.7e-163 eaeH M Domain of Unknown Function (DUF1259)
GLFLGHEG_03621 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
GLFLGHEG_03622 4.5e-166 K Transcriptional regulator
GLFLGHEG_03623 9.9e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
GLFLGHEG_03624 1.8e-249 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GLFLGHEG_03625 1.8e-130 ydfC EG EamA-like transporter family
GLFLGHEG_03626 4.3e-31 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
GLFLGHEG_03627 1.6e-77 S Protein of unknown function with HXXEE motif
GLFLGHEG_03628 1.7e-163 S Metal dependent phosphohydrolases with conserved 'HD' motif.
GLFLGHEG_03629 1.1e-30 yvdC S MazG nucleotide pyrophosphohydrolase domain
GLFLGHEG_03630 4.6e-100 yvdD 3.2.2.10 S Belongs to the LOG family
GLFLGHEG_03631 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
GLFLGHEG_03632 1.2e-163 yyaK S CAAX protease self-immunity
GLFLGHEG_03633 5.2e-248 ydjK G Sugar (and other) transporter
GLFLGHEG_03634 5.8e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GLFLGHEG_03635 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
GLFLGHEG_03636 1.6e-145 xth 3.1.11.2 L exodeoxyribonuclease III
GLFLGHEG_03637 1.8e-101 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GLFLGHEG_03638 3.9e-107 adaA 3.2.2.21 K Transcriptional regulator
GLFLGHEG_03639 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GLFLGHEG_03640 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GLFLGHEG_03641 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
GLFLGHEG_03642 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GLFLGHEG_03643 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GLFLGHEG_03644 2.3e-33 yyzM S protein conserved in bacteria
GLFLGHEG_03645 2.4e-176 yyaD S Membrane
GLFLGHEG_03646 9e-84 4.2.1.103 K FR47-like protein
GLFLGHEG_03647 6.2e-111 yyaC S Sporulation protein YyaC
GLFLGHEG_03648 7.9e-149 spo0J K Belongs to the ParB family
GLFLGHEG_03649 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
GLFLGHEG_03650 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
GLFLGHEG_03651 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
GLFLGHEG_03652 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GLFLGHEG_03653 3.6e-24 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GLFLGHEG_03654 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GLFLGHEG_03655 5.5e-110 jag S single-stranded nucleic acid binding R3H
GLFLGHEG_03656 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GLFLGHEG_03657 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GLFLGHEG_03658 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GLFLGHEG_03659 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GLFLGHEG_03660 2.4e-33 yaaA S S4 domain
GLFLGHEG_03661 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GLFLGHEG_03662 8.1e-38 yaaB S Domain of unknown function (DUF370)
GLFLGHEG_03663 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GLFLGHEG_03664 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GLFLGHEG_03665 3.4e-39 S COG NOG14552 non supervised orthologous group
GLFLGHEG_03668 4.4e-183 yaaC S YaaC-like Protein
GLFLGHEG_03669 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GLFLGHEG_03670 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GLFLGHEG_03671 1.3e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GLFLGHEG_03672 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GLFLGHEG_03673 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GLFLGHEG_03674 6.8e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GLFLGHEG_03675 1.3e-09
GLFLGHEG_03676 4.1e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
GLFLGHEG_03677 4.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
GLFLGHEG_03678 3.8e-211 yaaH M Glycoside Hydrolase Family
GLFLGHEG_03679 2.2e-99 yaaI Q COG1335 Amidases related to nicotinamidase
GLFLGHEG_03680 7.8e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GLFLGHEG_03681 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GLFLGHEG_03682 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GLFLGHEG_03683 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GLFLGHEG_03684 3.6e-32 yaaL S Protein of unknown function (DUF2508)
GLFLGHEG_03685 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
GLFLGHEG_03686 3.4e-39 S COG NOG14552 non supervised orthologous group
GLFLGHEG_03689 2.2e-30 csfB S Inhibitor of sigma-G Gin
GLFLGHEG_03690 8.6e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
GLFLGHEG_03691 1.2e-189 yaaN P Belongs to the TelA family
GLFLGHEG_03692 6.2e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
GLFLGHEG_03693 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GLFLGHEG_03694 7.5e-55 yaaQ S protein conserved in bacteria
GLFLGHEG_03695 1.2e-71 yaaR S protein conserved in bacteria
GLFLGHEG_03696 1.3e-182 holB 2.7.7.7 L DNA polymerase III
GLFLGHEG_03697 8.8e-145 yaaT S stage 0 sporulation protein
GLFLGHEG_03698 7.7e-37 yabA L Involved in initiation control of chromosome replication
GLFLGHEG_03699 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
GLFLGHEG_03700 4.7e-48 yazA L endonuclease containing a URI domain
GLFLGHEG_03701 5.3e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GLFLGHEG_03702 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
GLFLGHEG_03703 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GLFLGHEG_03704 2e-143 tatD L hydrolase, TatD
GLFLGHEG_03705 1.8e-232 rpfB GH23 T protein conserved in bacteria
GLFLGHEG_03706 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GLFLGHEG_03707 1.1e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GLFLGHEG_03708 8.4e-146 yabG S peptidase
GLFLGHEG_03709 7.8e-39 veg S protein conserved in bacteria
GLFLGHEG_03710 2.9e-27 sspF S DNA topological change
GLFLGHEG_03711 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GLFLGHEG_03712 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
GLFLGHEG_03713 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
GLFLGHEG_03714 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
GLFLGHEG_03715 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GLFLGHEG_03716 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GLFLGHEG_03717 2e-106 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GLFLGHEG_03718 9.4e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GLFLGHEG_03719 3.7e-40 yabK S Peptide ABC transporter permease
GLFLGHEG_03720 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GLFLGHEG_03721 6.2e-91 spoVT K stage V sporulation protein
GLFLGHEG_03722 2e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GLFLGHEG_03723 2.3e-276 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
GLFLGHEG_03724 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GLFLGHEG_03725 1.9e-49 yabP S Sporulation protein YabP
GLFLGHEG_03726 5.8e-104 yabQ S spore cortex biosynthesis protein
GLFLGHEG_03727 4.1e-57 divIC D Septum formation initiator
GLFLGHEG_03728 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
GLFLGHEG_03731 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
GLFLGHEG_03732 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
GLFLGHEG_03733 4.7e-185 KLT serine threonine protein kinase
GLFLGHEG_03734 1.1e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GLFLGHEG_03735 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GLFLGHEG_03736 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GLFLGHEG_03737 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GLFLGHEG_03738 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GLFLGHEG_03739 3.1e-156 yacD 5.2.1.8 O peptidyl-prolyl isomerase
GLFLGHEG_03740 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GLFLGHEG_03741 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GLFLGHEG_03742 1.4e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
GLFLGHEG_03743 1.2e-160 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
GLFLGHEG_03744 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GLFLGHEG_03745 2.9e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GLFLGHEG_03746 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GLFLGHEG_03747 4.5e-29 yazB K transcriptional
GLFLGHEG_03748 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GLFLGHEG_03749 9.3e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GLFLGHEG_03750 3.4e-39 S COG NOG14552 non supervised orthologous group
GLFLGHEG_03752 1.3e-07
GLFLGHEG_03755 2e-08
GLFLGHEG_03760 3.4e-39 S COG NOG14552 non supervised orthologous group
GLFLGHEG_03761 7.5e-77 ctsR K Belongs to the CtsR family
GLFLGHEG_03762 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
GLFLGHEG_03763 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
GLFLGHEG_03764 0.0 clpC O Belongs to the ClpA ClpB family
GLFLGHEG_03765 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GLFLGHEG_03766 6.4e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GLFLGHEG_03767 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
GLFLGHEG_03768 7.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GLFLGHEG_03769 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
GLFLGHEG_03770 8.1e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GLFLGHEG_03771 1e-116 cysE 2.3.1.30 E Serine acetyltransferase
GLFLGHEG_03772 5.3e-60 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GLFLGHEG_03773 2.2e-196 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GLFLGHEG_03774 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GLFLGHEG_03775 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GLFLGHEG_03776 2.8e-88 yacP S RNA-binding protein containing a PIN domain
GLFLGHEG_03777 8.9e-116 sigH K Belongs to the sigma-70 factor family
GLFLGHEG_03778 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GLFLGHEG_03779 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
GLFLGHEG_03780 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GLFLGHEG_03781 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GLFLGHEG_03782 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GLFLGHEG_03783 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GLFLGHEG_03784 9.7e-109 rsmC 2.1.1.172 J Methyltransferase
GLFLGHEG_03785 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GLFLGHEG_03786 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GLFLGHEG_03787 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
GLFLGHEG_03788 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GLFLGHEG_03789 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GLFLGHEG_03790 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GLFLGHEG_03791 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GLFLGHEG_03792 1.5e-188 ybaC 3.4.11.5 S Alpha/beta hydrolase family
GLFLGHEG_03793 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
GLFLGHEG_03794 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GLFLGHEG_03795 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
GLFLGHEG_03796 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GLFLGHEG_03797 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GLFLGHEG_03798 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GLFLGHEG_03799 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GLFLGHEG_03800 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GLFLGHEG_03801 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GLFLGHEG_03802 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
GLFLGHEG_03803 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GLFLGHEG_03804 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GLFLGHEG_03805 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GLFLGHEG_03806 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GLFLGHEG_03807 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GLFLGHEG_03808 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GLFLGHEG_03809 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GLFLGHEG_03810 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GLFLGHEG_03811 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GLFLGHEG_03812 1.9e-23 rpmD J Ribosomal protein L30
GLFLGHEG_03813 4.1e-72 rplO J binds to the 23S rRNA
GLFLGHEG_03814 1.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GLFLGHEG_03815 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GLFLGHEG_03816 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
GLFLGHEG_03817 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GLFLGHEG_03818 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GLFLGHEG_03819 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GLFLGHEG_03820 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GLFLGHEG_03821 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GLFLGHEG_03822 4.7e-58 rplQ J Ribosomal protein L17
GLFLGHEG_03823 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GLFLGHEG_03824 2.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GLFLGHEG_03825 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GLFLGHEG_03826 1.8e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GLFLGHEG_03827 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GLFLGHEG_03828 3.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
GLFLGHEG_03829 3.1e-144 ybaJ Q Methyltransferase domain
GLFLGHEG_03830 5.9e-85 yizA S Damage-inducible protein DinB
GLFLGHEG_03831 1.7e-78 ybaK S Protein of unknown function (DUF2521)
GLFLGHEG_03832 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GLFLGHEG_03833 1.5e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
GLFLGHEG_03834 1.7e-75 gerD
GLFLGHEG_03835 2.6e-86 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
GLFLGHEG_03836 7.1e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
GLFLGHEG_03837 3.4e-39 S COG NOG14552 non supervised orthologous group
GLFLGHEG_03840 1.6e-08
GLFLGHEG_03843 3.4e-39 S COG NOG14552 non supervised orthologous group
GLFLGHEG_03844 5e-221 glcP G Major Facilitator Superfamily
GLFLGHEG_03845 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GLFLGHEG_03846 1.1e-178 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
GLFLGHEG_03847 7.6e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
GLFLGHEG_03848 6e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
GLFLGHEG_03849 1.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
GLFLGHEG_03850 5.1e-115 ybbA S Putative esterase
GLFLGHEG_03851 8e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLFLGHEG_03852 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GLFLGHEG_03853 2e-172 feuA P Iron-uptake system-binding protein
GLFLGHEG_03854 2.2e-311 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
GLFLGHEG_03855 1.2e-238 ybbC 3.2.1.52 S protein conserved in bacteria
GLFLGHEG_03856 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
GLFLGHEG_03857 1.5e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
GLFLGHEG_03858 2.7e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GLFLGHEG_03859 2.8e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GLFLGHEG_03860 1.1e-86 ybbJ J acetyltransferase
GLFLGHEG_03861 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
GLFLGHEG_03867 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
GLFLGHEG_03868 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
GLFLGHEG_03869 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GLFLGHEG_03870 1.3e-223 ybbR S protein conserved in bacteria
GLFLGHEG_03871 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GLFLGHEG_03872 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GLFLGHEG_03873 3.8e-154 V ATPases associated with a variety of cellular activities
GLFLGHEG_03874 8.3e-106 S ABC-2 family transporter protein
GLFLGHEG_03875 7e-100 ybdN
GLFLGHEG_03876 1.9e-132 ybdO S Domain of unknown function (DUF4885)
GLFLGHEG_03877 1.5e-163 dkgB S Aldo/keto reductase family
GLFLGHEG_03878 1e-93 yxaC M effector of murein hydrolase
GLFLGHEG_03879 6.9e-52 S LrgA family
GLFLGHEG_03880 8.8e-72 yxaD K helix_turn_helix multiple antibiotic resistance protein
GLFLGHEG_03881 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
GLFLGHEG_03882 1.1e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GLFLGHEG_03883 1.8e-103 T Histidine kinase
GLFLGHEG_03884 4.9e-82 KT helix_turn_helix, Lux Regulon
GLFLGHEG_03885 3.5e-134 V ABC transporter, ATP-binding protein
GLFLGHEG_03886 3.4e-145 V ABC-2 type transporter
GLFLGHEG_03887 6e-123 V ABC-2 type transporter
GLFLGHEG_03888 4.4e-14
GLFLGHEG_03889 9.6e-60 bacT Q Thioesterase domain
GLFLGHEG_03890 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
GLFLGHEG_03891 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
GLFLGHEG_03892 4.6e-121 fabD 2.3.1.39 I PFAM Acyl transferase
GLFLGHEG_03893 0.0 Q Beta-ketoacyl synthase
GLFLGHEG_03894 0.0 Q Polyketide synthase modules and related proteins
GLFLGHEG_03895 1.5e-102 Q Flavin containing amine oxidoreductase
GLFLGHEG_03896 0.0 Q TIGRFAM amino acid adenylation domain
GLFLGHEG_03897 3.5e-50 crtF 2.1.1.210 Q PFAM O-methyltransferase
GLFLGHEG_03898 9.1e-78 S Domain of unknown function (DUF4879)
GLFLGHEG_03899 1.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
GLFLGHEG_03900 1.2e-33 yqeB
GLFLGHEG_03901 7.6e-57 yqeB
GLFLGHEG_03902 9.2e-40 ybyB
GLFLGHEG_03903 2.5e-292 ybeC E amino acid
GLFLGHEG_03904 2.4e-45 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GLFLGHEG_03905 1.9e-55
GLFLGHEG_03906 3.4e-15 S Protein of unknown function (DUF2651)
GLFLGHEG_03907 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GLFLGHEG_03908 3e-259 glpT G -transporter
GLFLGHEG_03909 1.3e-16 S Protein of unknown function (DUF2651)
GLFLGHEG_03910 4.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
GLFLGHEG_03912 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
GLFLGHEG_03913 1.3e-30
GLFLGHEG_03914 1.2e-82 K Helix-turn-helix XRE-family like proteins
GLFLGHEG_03915 1.1e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
GLFLGHEG_03916 1.8e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GLFLGHEG_03917 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GLFLGHEG_03918 1.9e-86 ybfM S SNARE associated Golgi protein
GLFLGHEG_03919 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
GLFLGHEG_03920 1.2e-42 ybfN
GLFLGHEG_03921 8.6e-192 yceA S Belongs to the UPF0176 family
GLFLGHEG_03922 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GLFLGHEG_03923 1.9e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
GLFLGHEG_03924 1.8e-257 mmuP E amino acid
GLFLGHEG_03925 7.1e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
GLFLGHEG_03926 2.7e-258 agcS E Sodium alanine symporter
GLFLGHEG_03927 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
GLFLGHEG_03928 1.5e-212 phoQ 2.7.13.3 T Histidine kinase
GLFLGHEG_03929 1.9e-172 glnL T Regulator
GLFLGHEG_03930 2.7e-29 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
GLFLGHEG_03931 9.8e-20 L Transposase
GLFLGHEG_03932 1.2e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GLFLGHEG_03933 9.6e-112 ydfN C nitroreductase
GLFLGHEG_03934 4e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
GLFLGHEG_03935 1.5e-62 mhqP S DoxX
GLFLGHEG_03936 1.6e-55 traF CO Thioredoxin
GLFLGHEG_03937 5.6e-62 ycbP S Protein of unknown function (DUF2512)
GLFLGHEG_03938 5.1e-80 sleB 3.5.1.28 M Cell wall
GLFLGHEG_03939 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
GLFLGHEG_03940 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GLFLGHEG_03941 3e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GLFLGHEG_03942 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GLFLGHEG_03943 3.1e-209 ycbU E Selenocysteine lyase
GLFLGHEG_03944 6.9e-238 lmrB EGP the major facilitator superfamily
GLFLGHEG_03945 1.2e-100 yxaF K Transcriptional regulator
GLFLGHEG_03946 1.2e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GLFLGHEG_03947 3.4e-112 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
GLFLGHEG_03948 1.3e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
GLFLGHEG_03949 6.2e-171 yccK C Aldo keto reductase
GLFLGHEG_03950 6.2e-177 ycdA S Domain of unknown function (DUF5105)
GLFLGHEG_03951 1.6e-263 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
GLFLGHEG_03952 2.4e-134 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
GLFLGHEG_03953 3.6e-102 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
GLFLGHEG_03954 7.6e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
GLFLGHEG_03955 2.5e-43 S response regulator aspartate phosphatase
GLFLGHEG_03956 3.2e-49 S response regulator aspartate phosphatase
GLFLGHEG_03957 3.9e-63 IQ Enoyl-(Acyl carrier protein) reductase
GLFLGHEG_03958 8.1e-18 IQ Enoyl-(Acyl carrier protein) reductase
GLFLGHEG_03959 1.3e-111 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
GLFLGHEG_03960 4.8e-46 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
GLFLGHEG_03961 1.5e-112 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
GLFLGHEG_03962 3.5e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
GLFLGHEG_03963 7.2e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GLFLGHEG_03964 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GLFLGHEG_03965 1.6e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GLFLGHEG_03966 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
GLFLGHEG_03967 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
GLFLGHEG_03968 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
GLFLGHEG_03969 9.7e-138 terC P Protein of unknown function (DUF475)
GLFLGHEG_03970 0.0 yceG S Putative component of 'biosynthetic module'
GLFLGHEG_03971 8.7e-193 yceH P Belongs to the TelA family
GLFLGHEG_03972 1.2e-214 naiP P Uncharacterised MFS-type transporter YbfB
GLFLGHEG_03975 5.3e-23 D minor tail protein
GLFLGHEG_03976 3.8e-15 D Phage-related minor tail protein
GLFLGHEG_03977 3.5e-25 D Phage tail tape measure protein
GLFLGHEG_03979 5.7e-10 D Phage tail tape measure protein
GLFLGHEG_03980 3e-07 D minor tail protein
GLFLGHEG_03982 2.1e-16 S Phage tail protein
GLFLGHEG_03983 1.7e-107 sidC L Phage minor structural protein
GLFLGHEG_03985 1.6e-44 sidC L Phage minor structural protein
GLFLGHEG_03987 6.2e-54 S Bacteriophage holin family
GLFLGHEG_03988 2.4e-69 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GLFLGHEG_03989 5.5e-45 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
GLFLGHEG_03990 8.9e-49 S Protein of unknown function (DUF3800)
GLFLGHEG_03991 6.3e-74 S Pfam:DUF867
GLFLGHEG_03992 3.2e-15
GLFLGHEG_03993 1.3e-24
GLFLGHEG_03995 2.2e-105 D Cellulose biosynthesis protein BcsQ
GLFLGHEG_03998 1.6e-35 K Helix-turn-helix
GLFLGHEG_04000 8.8e-10
GLFLGHEG_04002 1.6e-50 S Bacteriophage Mu Gam like protein
GLFLGHEG_04003 3e-79 S ERF superfamily
GLFLGHEG_04007 4.7e-38 S Recombination protein U
GLFLGHEG_04008 4.9e-57 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GLFLGHEG_04011 3.8e-07
GLFLGHEG_04017 1.2e-17
GLFLGHEG_04019 1.8e-24
GLFLGHEG_04022 2.6e-29 sigF K sigma factor activity
GLFLGHEG_04024 3.9e-34 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GLFLGHEG_04026 3.9e-31 xtmA L Terminase small subunit
GLFLGHEG_04027 1.3e-203 S Phage terminase, large subunit, PBSX family
GLFLGHEG_04028 6.7e-164 S portal protein
GLFLGHEG_04029 2.9e-90 S Phage minor capsid protein 2
GLFLGHEG_04031 2.6e-35
GLFLGHEG_04032 2.8e-120
GLFLGHEG_04034 7.4e-13
GLFLGHEG_04035 3.3e-28
GLFLGHEG_04036 1.4e-16 S Minor capsid protein
GLFLGHEG_04037 2.7e-31 S Minor capsid protein
GLFLGHEG_04038 1.2e-22 S Minor capsid protein from bacteriophage
GLFLGHEG_04039 5.4e-43 N Belongs to the glycosyl hydrolase family 6
GLFLGHEG_04040 1.8e-07 malS 3.2.1.1 GH13 G Carbohydrate binding domain
GLFLGHEG_04041 3.2e-09 chiB 3.2.1.14 GH18 G Carbohydrate binding domain
GLFLGHEG_04042 1.5e-14
GLFLGHEG_04043 5.6e-38 S Bacteriophage Gp15 protein
GLFLGHEG_04044 3.6e-115 D Phage-related minor tail protein
GLFLGHEG_04045 7.2e-34 S Phage tail protein
GLFLGHEG_04046 9.6e-161 sidC L Phage minor structural protein
GLFLGHEG_04048 6.2e-54 S Bacteriophage holin family
GLFLGHEG_04049 2.3e-90 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
GLFLGHEG_04050 8.9e-49 S Protein of unknown function (DUF3800)
GLFLGHEG_04051 6.3e-74 S Pfam:DUF867
GLFLGHEG_04052 3.2e-15
GLFLGHEG_04053 1.3e-24
GLFLGHEG_04055 2.2e-105 D Cellulose biosynthesis protein BcsQ
GLFLGHEG_04058 1.6e-35 K Helix-turn-helix
GLFLGHEG_04060 8.8e-10
GLFLGHEG_04062 1.6e-50 S Bacteriophage Mu Gam like protein
GLFLGHEG_04063 3e-79 S ERF superfamily
GLFLGHEG_04067 1.9e-26 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GLFLGHEG_04068 4.9e-57 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GLFLGHEG_04071 3.8e-07
GLFLGHEG_04078 9.1e-13
GLFLGHEG_04080 6.2e-24
GLFLGHEG_04083 2.6e-29 sigF K sigma factor activity
GLFLGHEG_04085 3.9e-34 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GLFLGHEG_04087 1.9e-23 L Terminase small subunit

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)