ORF_ID e_value Gene_name EC_number CAZy COGs Description
NPPOIMGL_00001 1.1e-68 glnR K transcriptional
NPPOIMGL_00002 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NPPOIMGL_00003 1.6e-217 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPPOIMGL_00004 8.7e-69 spoVK O stage V sporulation protein K
NPPOIMGL_00005 9.7e-98 spoVK O stage V sporulation protein K
NPPOIMGL_00006 1.3e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPPOIMGL_00007 1.9e-107 ymaB
NPPOIMGL_00008 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPPOIMGL_00009 1.7e-99 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPPOIMGL_00010 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPPOIMGL_00011 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NPPOIMGL_00012 4.5e-22 ymzA
NPPOIMGL_00013 8.2e-23
NPPOIMGL_00014 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NPPOIMGL_00015 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPPOIMGL_00016 2.1e-46 ymaF S YmaF family
NPPOIMGL_00018 5.4e-50 ebrA P Small Multidrug Resistance protein
NPPOIMGL_00019 8.9e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NPPOIMGL_00020 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
NPPOIMGL_00021 2.1e-126 ymaC S Replication protein
NPPOIMGL_00022 1.9e-07 K Transcriptional regulator
NPPOIMGL_00023 1.3e-251 aprX O Belongs to the peptidase S8 family
NPPOIMGL_00024 2.1e-162 ymaE S Metallo-beta-lactamase superfamily
NPPOIMGL_00025 2.2e-60 ymzB
NPPOIMGL_00026 1.8e-231 cypA C Cytochrome P450
NPPOIMGL_00027 0.0 pks13 HQ Beta-ketoacyl synthase
NPPOIMGL_00028 0.0 dhbF IQ polyketide synthase
NPPOIMGL_00029 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NPPOIMGL_00030 0.0 pfaA Q Polyketide synthase of type I
NPPOIMGL_00031 0.0 rhiB IQ polyketide synthase
NPPOIMGL_00032 1.5e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NPPOIMGL_00033 5.5e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
NPPOIMGL_00034 1.5e-244 pksG 2.3.3.10 I synthase
NPPOIMGL_00035 3.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPPOIMGL_00036 1.4e-37 acpK IQ Phosphopantetheine attachment site
NPPOIMGL_00037 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NPPOIMGL_00038 2.3e-184 pksD Q Acyl transferase domain
NPPOIMGL_00039 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NPPOIMGL_00041 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
NPPOIMGL_00042 1.9e-107 pksA K Transcriptional regulator
NPPOIMGL_00043 6e-97 ymcC S Membrane
NPPOIMGL_00044 2.1e-69 S Regulatory protein YrvL
NPPOIMGL_00045 6.7e-139 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPPOIMGL_00046 2e-217 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPPOIMGL_00047 2e-26 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPPOIMGL_00048 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPPOIMGL_00049 2.2e-88 cotE S Spore coat protein
NPPOIMGL_00050 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NPPOIMGL_00051 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NPPOIMGL_00052 1.2e-211 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NPPOIMGL_00053 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NPPOIMGL_00054 1.2e-36 spoVS S Stage V sporulation protein S
NPPOIMGL_00055 1.9e-152 ymdB S protein conserved in bacteria
NPPOIMGL_00056 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NPPOIMGL_00057 8.8e-215 pbpX V Beta-lactamase
NPPOIMGL_00058 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPPOIMGL_00059 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
NPPOIMGL_00060 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPPOIMGL_00061 3.5e-118 ymfM S protein conserved in bacteria
NPPOIMGL_00062 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NPPOIMGL_00063 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NPPOIMGL_00064 3e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NPPOIMGL_00065 5.1e-240 ymfH S zinc protease
NPPOIMGL_00066 1.6e-233 ymfF S Peptidase M16
NPPOIMGL_00067 3.8e-205 ymfD EGP Major facilitator Superfamily
NPPOIMGL_00068 1.4e-133 ymfC K Transcriptional regulator
NPPOIMGL_00069 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NPPOIMGL_00070 4.4e-32 S YlzJ-like protein
NPPOIMGL_00071 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NPPOIMGL_00072 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPPOIMGL_00073 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPPOIMGL_00074 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NPPOIMGL_00075 4.1e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPPOIMGL_00076 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NPPOIMGL_00077 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NPPOIMGL_00078 2.6e-42 ymxH S YlmC YmxH family
NPPOIMGL_00079 4.4e-233 pepR S Belongs to the peptidase M16 family
NPPOIMGL_00080 1.4e-178 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NPPOIMGL_00081 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NPPOIMGL_00082 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPPOIMGL_00083 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NPPOIMGL_00084 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPPOIMGL_00085 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPPOIMGL_00086 3e-44 ylxP S protein conserved in bacteria
NPPOIMGL_00087 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPPOIMGL_00088 3.1e-47 ylxQ J ribosomal protein
NPPOIMGL_00089 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NPPOIMGL_00090 1.1e-203 nusA K Participates in both transcription termination and antitermination
NPPOIMGL_00091 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NPPOIMGL_00092 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPPOIMGL_00093 4.6e-302 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPPOIMGL_00094 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPPOIMGL_00095 7.7e-233 rasP M zinc metalloprotease
NPPOIMGL_00096 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NPPOIMGL_00097 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NPPOIMGL_00098 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPPOIMGL_00099 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPPOIMGL_00100 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NPPOIMGL_00101 1.4e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPPOIMGL_00102 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NPPOIMGL_00103 1.8e-76 ylxL
NPPOIMGL_00104 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPPOIMGL_00105 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NPPOIMGL_00106 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NPPOIMGL_00107 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NPPOIMGL_00108 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NPPOIMGL_00109 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NPPOIMGL_00110 3.3e-124 flhG D Belongs to the ParA family
NPPOIMGL_00111 1.3e-32 flhG D Belongs to the ParA family
NPPOIMGL_00112 1.1e-198 flhF N Flagellar biosynthesis regulator FlhF
NPPOIMGL_00113 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NPPOIMGL_00114 9.8e-182 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NPPOIMGL_00115 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NPPOIMGL_00116 2.2e-36 fliQ N Role in flagellar biosynthesis
NPPOIMGL_00117 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NPPOIMGL_00118 5.1e-95 fliZ N Flagellar biosynthesis protein, FliO
NPPOIMGL_00119 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NPPOIMGL_00120 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NPPOIMGL_00121 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NPPOIMGL_00122 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NPPOIMGL_00123 2.6e-32 flbD N protein, possibly involved in motility
NPPOIMGL_00124 1.3e-39 flgG N Flagellar basal body rod
NPPOIMGL_00125 1.7e-51 flgG N Flagellar basal body rod
NPPOIMGL_00126 2.3e-72 flgD N Flagellar basal body rod modification protein
NPPOIMGL_00127 4.4e-216 fliK N Flagellar hook-length control protein
NPPOIMGL_00128 2.2e-36 ylxF S MgtE intracellular N domain
NPPOIMGL_00129 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NPPOIMGL_00130 4.6e-97 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NPPOIMGL_00131 3.5e-149 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NPPOIMGL_00132 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NPPOIMGL_00133 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NPPOIMGL_00134 2.6e-254 fliF N The M ring may be actively involved in energy transduction
NPPOIMGL_00135 1.9e-31 fliE N Flagellar hook-basal body
NPPOIMGL_00136 9.9e-74 flgC N Belongs to the flagella basal body rod proteins family
NPPOIMGL_00137 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NPPOIMGL_00138 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NPPOIMGL_00139 4.6e-67 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPPOIMGL_00140 3.4e-162 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPPOIMGL_00141 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPPOIMGL_00142 2.5e-169 xerC L tyrosine recombinase XerC
NPPOIMGL_00143 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPPOIMGL_00144 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPPOIMGL_00145 4e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NPPOIMGL_00146 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NPPOIMGL_00147 4.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NPPOIMGL_00148 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NPPOIMGL_00149 2.4e-285 ylqG
NPPOIMGL_00150 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPPOIMGL_00151 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPPOIMGL_00152 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPPOIMGL_00153 6.9e-74 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NPPOIMGL_00154 7.3e-46 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NPPOIMGL_00155 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPPOIMGL_00156 6.3e-61 ylqD S YlqD protein
NPPOIMGL_00157 4.5e-36 ylqC S Belongs to the UPF0109 family
NPPOIMGL_00158 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NPPOIMGL_00159 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPPOIMGL_00160 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPPOIMGL_00165 1.6e-29 S Protein of unknown function (DUF1257)
NPPOIMGL_00167 1.9e-178 O ATPase family associated with various cellular activities (AAA)
NPPOIMGL_00171 1.6e-68
NPPOIMGL_00175 2.3e-92 nrdG 1.97.1.4 H queuosine metabolic process
NPPOIMGL_00179 1.1e-12
NPPOIMGL_00180 3.4e-54 S Prokaryotic E2 family D
NPPOIMGL_00183 2.6e-96 H ThiF family
NPPOIMGL_00184 2.2e-59
NPPOIMGL_00189 4.1e-22 dpo 3.2.2.27 L deaminated base DNA N-glycosylase activity
NPPOIMGL_00190 3.9e-122 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs
NPPOIMGL_00196 3e-31 DR0488 S 3D domain
NPPOIMGL_00198 4e-82 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NPPOIMGL_00201 1.1e-15
NPPOIMGL_00205 5.4e-10 S YopX protein
NPPOIMGL_00209 1.4e-16 S mRNA catabolic process
NPPOIMGL_00213 1.3e-228 rapA_2 L Superfamily II DNA RNA helicases, SNF2 family'
NPPOIMGL_00219 2.4e-39 rnhA 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
NPPOIMGL_00220 1.7e-32
NPPOIMGL_00222 2.2e-12 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPPOIMGL_00224 7.6e-27 smf LU Protein of unknown function (DUF2493)
NPPOIMGL_00240 3.9e-106 O Heat shock 70 kDa protein
NPPOIMGL_00242 1.3e-75
NPPOIMGL_00249 3.7e-241 S Mu-like prophage FluMu protein gp28
NPPOIMGL_00251 6.7e-205
NPPOIMGL_00252 2e-106
NPPOIMGL_00253 7.4e-156
NPPOIMGL_00254 1.4e-174
NPPOIMGL_00260 2.9e-12
NPPOIMGL_00262 3e-72 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPPOIMGL_00263 1.4e-89 ykoP G polysaccharide deacetylase
NPPOIMGL_00264 3.5e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NPPOIMGL_00265 0.0 ykoS
NPPOIMGL_00266 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NPPOIMGL_00267 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NPPOIMGL_00268 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NPPOIMGL_00269 3.5e-24 ydcR 2.7.7.65 T Diguanylate cyclase
NPPOIMGL_00270 4.2e-123
NPPOIMGL_00271 2.4e-37
NPPOIMGL_00272 8.9e-90 G SMI1-KNR4 cell-wall
NPPOIMGL_00274 5.5e-104 ynaC
NPPOIMGL_00275 8.3e-12 S Protein of unknown function (DUF1433)
NPPOIMGL_00276 3.5e-94 ynaD J Acetyltransferase (GNAT) domain
NPPOIMGL_00278 6.6e-77 S CAAX protease self-immunity
NPPOIMGL_00279 4.7e-08 S Uncharacterised protein family (UPF0715)
NPPOIMGL_00280 5.5e-20 K Cro/C1-type HTH DNA-binding domain
NPPOIMGL_00281 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NPPOIMGL_00282 0.0 yojO P Von Willebrand factor
NPPOIMGL_00283 5.4e-153 yojN S ATPase family associated with various cellular activities (AAA)
NPPOIMGL_00284 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NPPOIMGL_00285 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NPPOIMGL_00286 1.2e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NPPOIMGL_00287 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPPOIMGL_00293 1.1e-100 S response regulator aspartate phosphatase
NPPOIMGL_00295 4.8e-40 S Immunity protein 22
NPPOIMGL_00297 1.8e-78 yobL S Bacterial EndoU nuclease
NPPOIMGL_00298 1.7e-62 carD K Transcription factor
NPPOIMGL_00299 8.7e-30 cspL K Cold shock
NPPOIMGL_00300 3.2e-54 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NPPOIMGL_00301 3.7e-108 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NPPOIMGL_00302 7.2e-26
NPPOIMGL_00303 2.2e-09 K Helix-turn-helix XRE-family like proteins
NPPOIMGL_00304 5.6e-34 K Helix-turn-helix XRE-family like proteins
NPPOIMGL_00306 1.2e-27 K Helix-turn-helix domain
NPPOIMGL_00307 5.8e-10 K PFAM helix-turn-helix domain protein
NPPOIMGL_00308 7.7e-34 E Pfam:DUF955
NPPOIMGL_00309 7.6e-12
NPPOIMGL_00310 2.4e-13
NPPOIMGL_00314 9.3e-61 V abc transporter atp-binding protein
NPPOIMGL_00315 2e-76 K NB-ARC domain
NPPOIMGL_00316 3.3e-161 yyaM EG EamA-like transporter family
NPPOIMGL_00317 5.1e-61 yyaN K MerR HTH family regulatory protein
NPPOIMGL_00318 4e-14 S Putative amidase domain
NPPOIMGL_00320 5.6e-31 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NPPOIMGL_00321 6.6e-246 tetL EGP Major facilitator Superfamily
NPPOIMGL_00322 1.2e-64
NPPOIMGL_00323 6.7e-107 M lytic transglycosylase activity
NPPOIMGL_00326 2.2e-51
NPPOIMGL_00330 8.2e-105 S HTH-like domain
NPPOIMGL_00331 2.8e-42 S transposition, DNA-mediated
NPPOIMGL_00332 2.4e-07
NPPOIMGL_00334 8.8e-159 K Transcriptional regulator
NPPOIMGL_00335 1.5e-258 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPPOIMGL_00336 2.7e-277 cisA2 L Recombinase
NPPOIMGL_00337 1.5e-161 gltR K LysR substrate binding domain
NPPOIMGL_00338 1e-23 C COG2041 Sulfite oxidase and related enzymes
NPPOIMGL_00339 1.3e-211 brnQ E Component of the transport system for branched-chain amino acids
NPPOIMGL_00340 9.6e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NPPOIMGL_00341 1.8e-136 azlC E AzlC protein
NPPOIMGL_00342 6.3e-79 bkdR K helix_turn_helix ASNC type
NPPOIMGL_00343 4.2e-16 yrdF K ribonuclease inhibitor
NPPOIMGL_00344 2.6e-186 esaA S type VII secretion protein EsaA
NPPOIMGL_00345 1.1e-31 esaA S type VII secretion protein EsaA
NPPOIMGL_00346 3.3e-64 yueC S Family of unknown function (DUF5383)
NPPOIMGL_00347 8.4e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_00348 4.8e-96 yueE S phosphohydrolase
NPPOIMGL_00349 2.9e-24 S Protein of unknown function (DUF2642)
NPPOIMGL_00350 7.2e-37 S Protein of unknown function (DUF2283)
NPPOIMGL_00351 5.4e-190 yueF S transporter activity
NPPOIMGL_00352 6.6e-31 yueG S Spore germination protein gerPA/gerPF
NPPOIMGL_00353 7.4e-39 yueH S YueH-like protein
NPPOIMGL_00354 1.1e-43 yueI S Protein of unknown function (DUF1694)
NPPOIMGL_00355 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
NPPOIMGL_00356 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPPOIMGL_00357 1.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NPPOIMGL_00358 3.8e-23 yuzC
NPPOIMGL_00360 7.8e-137 comQ H Belongs to the FPP GGPP synthase family
NPPOIMGL_00362 0.0 comP 2.7.13.3 T Histidine kinase
NPPOIMGL_00363 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPPOIMGL_00364 8.2e-52 ydiI Q protein, possibly involved in aromatic compounds catabolism
NPPOIMGL_00365 2.8e-58 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NPPOIMGL_00366 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPPOIMGL_00367 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPPOIMGL_00368 2.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPPOIMGL_00369 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPPOIMGL_00370 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NPPOIMGL_00371 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NPPOIMGL_00372 5e-15
NPPOIMGL_00373 8.2e-233 maeN C COG3493 Na citrate symporter
NPPOIMGL_00374 2.9e-151 yufQ S Belongs to the binding-protein-dependent transport system permease family
NPPOIMGL_00375 1.9e-13 yufQ S Belongs to the binding-protein-dependent transport system permease family
NPPOIMGL_00376 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
NPPOIMGL_00377 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NPPOIMGL_00378 2.4e-183 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NPPOIMGL_00379 1.5e-123 dcuR T COG4565 Response regulator of citrate malate metabolism
NPPOIMGL_00380 4.9e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NPPOIMGL_00381 6.3e-78 yufK S Family of unknown function (DUF5366)
NPPOIMGL_00382 5.3e-74 yuxK S protein conserved in bacteria
NPPOIMGL_00383 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NPPOIMGL_00384 1.9e-184 yuxJ EGP Major facilitator Superfamily
NPPOIMGL_00386 4.6e-114 kapD L the KinA pathway to sporulation
NPPOIMGL_00387 3.3e-70 kapB G Kinase associated protein B
NPPOIMGL_00388 3.9e-232 T PhoQ Sensor
NPPOIMGL_00389 8.4e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NPPOIMGL_00390 4.6e-39 yugE S Domain of unknown function (DUF1871)
NPPOIMGL_00391 4.9e-156 yugF I Hydrolase
NPPOIMGL_00392 1.6e-85 alaR K Transcriptional regulator
NPPOIMGL_00393 4.9e-20 yugH 2.6.1.1 E Aminotransferase
NPPOIMGL_00394 1.2e-169 yugH 2.6.1.1 E Aminotransferase
NPPOIMGL_00395 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NPPOIMGL_00396 1.1e-34 yuzA S Domain of unknown function (DUF378)
NPPOIMGL_00397 3.8e-187 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NPPOIMGL_00398 1.9e-43 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NPPOIMGL_00399 1.8e-228 yugK C Dehydrogenase
NPPOIMGL_00400 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NPPOIMGL_00402 6.3e-72 yugN S YugN-like family
NPPOIMGL_00403 1.1e-181 yugO P COG1226 Kef-type K transport systems
NPPOIMGL_00404 1.1e-53 mstX S Membrane-integrating protein Mistic
NPPOIMGL_00405 2.3e-38
NPPOIMGL_00406 1.4e-116 yugP S Zn-dependent protease
NPPOIMGL_00407 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NPPOIMGL_00408 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NPPOIMGL_00410 3.1e-71 yugU S Uncharacterised protein family UPF0047
NPPOIMGL_00411 9.2e-62 yugU S Uncharacterised protein family UPF0047
NPPOIMGL_00412 1e-35
NPPOIMGL_00413 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NPPOIMGL_00414 3.9e-82 mcpA NT chemotaxis protein
NPPOIMGL_00415 1e-164 mcpA NT chemotaxis protein
NPPOIMGL_00417 5e-180 mcpA NT chemotaxis protein
NPPOIMGL_00418 4.2e-38 mcpA NT chemotaxis protein
NPPOIMGL_00419 1.4e-79 mcpA NT chemotaxis protein
NPPOIMGL_00420 1.2e-201 mcpA NT chemotaxis protein
NPPOIMGL_00421 7.3e-238 mcpA NT chemotaxis protein
NPPOIMGL_00422 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NPPOIMGL_00423 3.8e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NPPOIMGL_00424 1.8e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NPPOIMGL_00425 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NPPOIMGL_00426 9.1e-250 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NPPOIMGL_00427 9.7e-183 ygjR S Oxidoreductase
NPPOIMGL_00428 6.2e-54 yubA S transporter activity
NPPOIMGL_00429 5.5e-35
NPPOIMGL_00430 1.8e-65
NPPOIMGL_00431 6.6e-60
NPPOIMGL_00432 1.4e-36
NPPOIMGL_00433 3.6e-44 xkdW S XkdW protein
NPPOIMGL_00434 6.7e-20
NPPOIMGL_00435 1.9e-148 xepA
NPPOIMGL_00436 3.3e-27 xhlA S Haemolysin XhlA
NPPOIMGL_00437 1.5e-20 xhlB S SPP1 phage holin
NPPOIMGL_00438 1.3e-52 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NPPOIMGL_00439 4.4e-52 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NPPOIMGL_00440 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPPOIMGL_00441 3.1e-95 yqaB E IrrE N-terminal-like domain
NPPOIMGL_00443 1.1e-11 S Protein of unknown function (DUF4064)
NPPOIMGL_00444 3e-33 K sequence-specific DNA binding
NPPOIMGL_00445 1.1e-09 K Helix-turn-helix XRE-family like proteins
NPPOIMGL_00447 2.2e-102
NPPOIMGL_00451 1.2e-174 yqaJ L YqaJ-like viral recombinase domain
NPPOIMGL_00452 6.1e-149 recT L RecT family
NPPOIMGL_00453 2e-109 3.1.3.16 L DnaD domain protein
NPPOIMGL_00454 4.3e-135 xkdC L IstB-like ATP binding protein
NPPOIMGL_00456 1.1e-71 rusA L Endodeoxyribonuclease RusA
NPPOIMGL_00457 1e-93 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NPPOIMGL_00458 7.8e-85 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NPPOIMGL_00459 1.5e-62 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NPPOIMGL_00460 3.6e-45 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_00461 4e-306 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_00462 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_00463 2.7e-88 M Glycosyltransferase like family 2
NPPOIMGL_00464 1.6e-99 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NPPOIMGL_00465 9.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NPPOIMGL_00466 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPPOIMGL_00467 7.9e-39 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NPPOIMGL_00469 1.5e-123 S P22 coat protein - gene protein 5
NPPOIMGL_00470 3.2e-58 S Domain of unknown function (DUF4355)
NPPOIMGL_00471 1e-161 S Phage portal protein, SPP1 Gp6-like
NPPOIMGL_00472 1.4e-162 S Terminase RNAseH like domain
NPPOIMGL_00473 1.6e-23 yqaS L DNA packaging
NPPOIMGL_00474 6.5e-97 D Phage tail tape measure protein
NPPOIMGL_00475 3e-40 3.5.1.28 M LysM domain
NPPOIMGL_00476 1.6e-08
NPPOIMGL_00477 2.3e-20
NPPOIMGL_00478 2.9e-11
NPPOIMGL_00479 8e-89
NPPOIMGL_00480 4.7e-23
NPPOIMGL_00481 4.8e-23 S Protein of unknown function (DUF2634)
NPPOIMGL_00482 1.7e-179 msbA2 3.6.3.44 V ABC transporter
NPPOIMGL_00483 7.6e-277 S COG0457 FOG TPR repeat
NPPOIMGL_00484 9.3e-58 usp CBM50 M protein conserved in bacteria
NPPOIMGL_00485 6.3e-23 usp CBM50 M protein conserved in bacteria
NPPOIMGL_00486 7.5e-33
NPPOIMGL_00487 2e-297 lytB 3.5.1.28 D Stage II sporulation protein
NPPOIMGL_00488 1.8e-233 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPPOIMGL_00489 1.3e-57 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NPPOIMGL_00490 9.6e-40
NPPOIMGL_00491 2e-221
NPPOIMGL_00492 4.1e-56 xkdW S XkdW protein
NPPOIMGL_00493 6.5e-23
NPPOIMGL_00494 8.3e-165 xepA
NPPOIMGL_00495 2.6e-68 S Bacteriophage holin family
NPPOIMGL_00496 5.2e-86 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NPPOIMGL_00497 1.3e-09
NPPOIMGL_00504 2e-08
NPPOIMGL_00507 2.5e-09 K Transcriptional regulator
NPPOIMGL_00508 3.1e-13
NPPOIMGL_00510 3.7e-135 S Histidine kinase
NPPOIMGL_00511 1.6e-14 S Histidine kinase
NPPOIMGL_00512 1.8e-125 yobL S Bacterial EndoU nuclease
NPPOIMGL_00513 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NPPOIMGL_00515 2.9e-66 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NPPOIMGL_00516 2.6e-103 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NPPOIMGL_00517 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NPPOIMGL_00519 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NPPOIMGL_00520 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
NPPOIMGL_00521 5.3e-205 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NPPOIMGL_00522 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
NPPOIMGL_00523 2.6e-129 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NPPOIMGL_00524 7.1e-120 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NPPOIMGL_00525 2.6e-52 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NPPOIMGL_00526 2.7e-132 kipR K Transcriptional regulator
NPPOIMGL_00527 3.5e-117 ycsK E anatomical structure formation involved in morphogenesis
NPPOIMGL_00529 1.4e-49 yczJ S biosynthesis
NPPOIMGL_00530 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NPPOIMGL_00531 4.2e-166 ydhF S Oxidoreductase
NPPOIMGL_00532 0.0 mtlR K transcriptional regulator, MtlR
NPPOIMGL_00533 2.2e-137 ydaB IQ acyl-CoA ligase
NPPOIMGL_00534 1e-61 ydaB IQ acyl-CoA ligase
NPPOIMGL_00535 1.3e-96 ydaB IQ acyl-CoA ligase
NPPOIMGL_00536 6.4e-97 ydaC Q Methyltransferase domain
NPPOIMGL_00537 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_00538 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NPPOIMGL_00539 6.8e-101 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPPOIMGL_00540 6.8e-77 ydaG 1.4.3.5 S general stress protein
NPPOIMGL_00541 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NPPOIMGL_00542 3.6e-45 ydzA EGP Major facilitator Superfamily
NPPOIMGL_00543 2.5e-74 lrpC K Transcriptional regulator
NPPOIMGL_00544 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPPOIMGL_00545 1.2e-36 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPPOIMGL_00546 4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NPPOIMGL_00547 2.5e-150 ydaK T Diguanylate cyclase, GGDEF domain
NPPOIMGL_00548 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NPPOIMGL_00549 4.5e-233 ydaM M Glycosyl transferase family group 2
NPPOIMGL_00550 0.0 ydaN S Bacterial cellulose synthase subunit
NPPOIMGL_00551 0.0 ydaO E amino acid
NPPOIMGL_00552 1.3e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NPPOIMGL_00553 1.9e-145 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NPPOIMGL_00554 1.2e-177 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NPPOIMGL_00555 2.1e-39
NPPOIMGL_00556 3.2e-125 mntH P H( )-stimulated, divalent metal cation uptake system
NPPOIMGL_00557 1.4e-89 mntH P H( )-stimulated, divalent metal cation uptake system
NPPOIMGL_00559 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NPPOIMGL_00560 1.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NPPOIMGL_00562 2.6e-58 ydbB G Cupin domain
NPPOIMGL_00563 1.8e-62 ydbC S Domain of unknown function (DUF4937
NPPOIMGL_00564 2.3e-153 ydbD P Catalase
NPPOIMGL_00565 3.9e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NPPOIMGL_00566 8.1e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NPPOIMGL_00567 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
NPPOIMGL_00568 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPPOIMGL_00569 6.6e-154 ydbI S AI-2E family transporter
NPPOIMGL_00570 2.7e-128 ydbJ V ABC transporter, ATP-binding protein
NPPOIMGL_00571 6.1e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPPOIMGL_00572 2.7e-52 ydbL
NPPOIMGL_00573 2.2e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NPPOIMGL_00574 1.1e-18 S Fur-regulated basic protein B
NPPOIMGL_00575 2.2e-07 S Fur-regulated basic protein A
NPPOIMGL_00576 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPPOIMGL_00577 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NPPOIMGL_00578 1.6e-163 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NPPOIMGL_00579 1.4e-35 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NPPOIMGL_00580 2.8e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPPOIMGL_00581 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPPOIMGL_00582 2.1e-82 ydbS S Bacterial PH domain
NPPOIMGL_00583 3.3e-259 ydbT S Membrane
NPPOIMGL_00584 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NPPOIMGL_00585 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPPOIMGL_00586 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NPPOIMGL_00587 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPPOIMGL_00588 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NPPOIMGL_00589 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NPPOIMGL_00590 1.3e-143 rsbR T Positive regulator of sigma-B
NPPOIMGL_00591 5.2e-57 rsbS T antagonist
NPPOIMGL_00592 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NPPOIMGL_00593 7.1e-189 rsbU 3.1.3.3 KT phosphatase
NPPOIMGL_00594 3.2e-19 rsbV T Belongs to the anti-sigma-factor antagonist family
NPPOIMGL_00595 1.8e-24 rsbV T Belongs to the anti-sigma-factor antagonist family
NPPOIMGL_00596 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NPPOIMGL_00597 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPPOIMGL_00598 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NPPOIMGL_00599 5.7e-15 S Polyketide cyclase / dehydrase and lipid transport
NPPOIMGL_00600 4.3e-82 ydcG S EVE domain
NPPOIMGL_00601 5.1e-75 ydcH K helix_turn_helix multiple antibiotic resistance protein
NPPOIMGL_00602 0.0 yhgF K COG2183 Transcriptional accessory protein
NPPOIMGL_00603 2.6e-39 yhgF K COG2183 Transcriptional accessory protein
NPPOIMGL_00604 1.5e-82 ydcK S Belongs to the SprT family
NPPOIMGL_00608 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NPPOIMGL_00609 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NPPOIMGL_00610 5.7e-166 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NPPOIMGL_00611 5e-09 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NPPOIMGL_00612 9.5e-155 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NPPOIMGL_00613 1.4e-56 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NPPOIMGL_00614 1.8e-110 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NPPOIMGL_00615 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NPPOIMGL_00616 9.9e-77 tspO T membrane
NPPOIMGL_00617 3.8e-96 cotI S Spore coat protein
NPPOIMGL_00618 8.4e-99 cotI S Spore coat protein
NPPOIMGL_00619 7.9e-132 cotSA M Glycosyl transferases group 1
NPPOIMGL_00620 1.3e-84 cotSA M Glycosyl transferases group 1
NPPOIMGL_00621 4.7e-118 cotS S Seems to be required for the assembly of the CotSA protein in spores
NPPOIMGL_00622 3.3e-106 cotS S Seems to be required for the assembly of the CotSA protein in spores
NPPOIMGL_00624 1.3e-232 ytcC M Glycosyltransferase Family 4
NPPOIMGL_00625 2.2e-176 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NPPOIMGL_00626 6.8e-10 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NPPOIMGL_00627 4.4e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPPOIMGL_00628 1.9e-152 galU 2.7.7.9 M Nucleotidyl transferase
NPPOIMGL_00629 4.5e-127 dksA T COG1734 DnaK suppressor protein
NPPOIMGL_00630 9.4e-272 menF 5.4.4.2 HQ Isochorismate synthase
NPPOIMGL_00631 2.5e-230 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NPPOIMGL_00632 2.6e-97 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NPPOIMGL_00633 1.1e-86 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NPPOIMGL_00634 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NPPOIMGL_00635 1.3e-67 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NPPOIMGL_00636 3.5e-202 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NPPOIMGL_00637 2.6e-129 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NPPOIMGL_00638 2e-76 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NPPOIMGL_00639 3.9e-170 troA P Belongs to the bacterial solute-binding protein 9 family
NPPOIMGL_00640 1.4e-76 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NPPOIMGL_00641 1.1e-53 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NPPOIMGL_00642 6.7e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NPPOIMGL_00643 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NPPOIMGL_00644 1.1e-24 S Domain of Unknown Function (DUF1540)
NPPOIMGL_00645 6.9e-136 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NPPOIMGL_00646 2.7e-36 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NPPOIMGL_00647 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
NPPOIMGL_00648 6.1e-41 rpmE2 J Ribosomal protein L31
NPPOIMGL_00649 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NPPOIMGL_00650 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPPOIMGL_00651 2.4e-72 ytkA S YtkA-like
NPPOIMGL_00653 2.1e-76 dps P Belongs to the Dps family
NPPOIMGL_00654 1.7e-61 ytkC S Bacteriophage holin family
NPPOIMGL_00655 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NPPOIMGL_00656 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NPPOIMGL_00657 1.4e-144 ytlC P ABC transporter
NPPOIMGL_00658 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NPPOIMGL_00659 3.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NPPOIMGL_00660 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NPPOIMGL_00661 8.8e-89 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NPPOIMGL_00662 1.4e-228 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NPPOIMGL_00663 4.7e-224 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPPOIMGL_00664 0.0 asnB 6.3.5.4 E Asparagine synthase
NPPOIMGL_00665 5.1e-245 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NPPOIMGL_00666 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NPPOIMGL_00667 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NPPOIMGL_00668 4.7e-106 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NPPOIMGL_00669 1.3e-122 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NPPOIMGL_00670 9.3e-95 ytqB J Putative rRNA methylase
NPPOIMGL_00671 2.3e-189 yhcC S Fe-S oxidoreductase
NPPOIMGL_00672 1.5e-40 ytzC S Protein of unknown function (DUF2524)
NPPOIMGL_00674 5.9e-47 S YolD-like protein
NPPOIMGL_00675 3.6e-63 K Protein of unknown function (DUF4065)
NPPOIMGL_00676 1.5e-10 S Motility quorum-sensing regulator, toxin of MqsA
NPPOIMGL_00677 2.3e-66 M NLP P60 protein
NPPOIMGL_00679 1e-91 xkdO L Transglycosylase SLT domain
NPPOIMGL_00680 2.3e-117 xkdP S Lysin motif
NPPOIMGL_00681 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NPPOIMGL_00682 1.4e-38 xkdR S Protein of unknown function (DUF2577)
NPPOIMGL_00683 1.9e-43 xkdS S Protein of unknown function (DUF2634)
NPPOIMGL_00684 5.8e-29 xkdS S Protein of unknown function (DUF2634)
NPPOIMGL_00685 3.7e-27 xkdS S Protein of unknown function (DUF2634)
NPPOIMGL_00686 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NPPOIMGL_00687 5.2e-196 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NPPOIMGL_00688 9.3e-48 S SMI1-KNR4 cell-wall
NPPOIMGL_00690 1.4e-42
NPPOIMGL_00691 2.1e-66 K Transcriptional regulator
NPPOIMGL_00693 2.7e-180 L Replication protein
NPPOIMGL_00695 7.4e-150 oppA E ABC transporter substrate-binding protein
NPPOIMGL_00696 4.7e-92 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NPPOIMGL_00697 6.1e-61 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NPPOIMGL_00698 5e-147 yjbA S Belongs to the UPF0736 family
NPPOIMGL_00699 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPPOIMGL_00700 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPPOIMGL_00701 8.2e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NPPOIMGL_00702 3.2e-267 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NPPOIMGL_00703 1.9e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPPOIMGL_00704 1.4e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPPOIMGL_00706 7.9e-96 ydiP 2.1.1.37 H C-5 cytosine-specific DNA methylase
NPPOIMGL_00709 7.1e-27 yqaO S Phage-like element PBSX protein XtrA
NPPOIMGL_00710 4.7e-19 S HNH endonuclease
NPPOIMGL_00711 3e-25 yqaO S Phage-like element PBSX protein XtrA
NPPOIMGL_00713 6.9e-26
NPPOIMGL_00716 4.7e-09 S dUTPase
NPPOIMGL_00717 1.5e-12 S dUTPase
NPPOIMGL_00723 9.5e-55 ynaE S Domain of unknown function (DUF3885)
NPPOIMGL_00724 3.5e-44 ynaE S Domain of unknown function (DUF3885)
NPPOIMGL_00725 3.5e-54 ynaD J Acetyltransferase (GNAT) domain
NPPOIMGL_00726 4e-36 L Transposase
NPPOIMGL_00727 1.2e-138 L HTH-like domain
NPPOIMGL_00728 4.6e-36 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
NPPOIMGL_00729 1.8e-161 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
NPPOIMGL_00730 2.3e-193 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NPPOIMGL_00731 2.9e-76 ctsR K Belongs to the CtsR family
NPPOIMGL_00732 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NPPOIMGL_00733 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NPPOIMGL_00734 0.0 clpC O Belongs to the ClpA ClpB family
NPPOIMGL_00735 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPPOIMGL_00736 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NPPOIMGL_00737 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NPPOIMGL_00738 4.8e-36 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NPPOIMGL_00739 1.3e-85 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NPPOIMGL_00740 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NPPOIMGL_00741 1.6e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPPOIMGL_00742 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NPPOIMGL_00743 2.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPPOIMGL_00744 4e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPPOIMGL_00745 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPPOIMGL_00746 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NPPOIMGL_00747 4.4e-115 sigH K Belongs to the sigma-70 factor family
NPPOIMGL_00748 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPPOIMGL_00749 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NPPOIMGL_00750 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPPOIMGL_00751 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPPOIMGL_00752 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPPOIMGL_00753 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPPOIMGL_00754 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NPPOIMGL_00755 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPPOIMGL_00756 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPPOIMGL_00757 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NPPOIMGL_00758 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPPOIMGL_00759 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPPOIMGL_00760 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPPOIMGL_00761 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPPOIMGL_00762 1.4e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NPPOIMGL_00763 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NPPOIMGL_00764 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPPOIMGL_00765 3e-105 rplD J Forms part of the polypeptide exit tunnel
NPPOIMGL_00766 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPPOIMGL_00767 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPPOIMGL_00768 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPPOIMGL_00769 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPPOIMGL_00770 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPPOIMGL_00771 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPPOIMGL_00772 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NPPOIMGL_00773 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPPOIMGL_00774 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPPOIMGL_00775 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPPOIMGL_00776 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPPOIMGL_00777 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPPOIMGL_00778 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPPOIMGL_00779 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPPOIMGL_00780 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPPOIMGL_00781 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPPOIMGL_00782 1.9e-23 rpmD J Ribosomal protein L30
NPPOIMGL_00783 1.8e-72 rplO J binds to the 23S rRNA
NPPOIMGL_00784 9.3e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPPOIMGL_00785 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPPOIMGL_00786 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NPPOIMGL_00787 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPPOIMGL_00788 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NPPOIMGL_00789 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPPOIMGL_00790 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPPOIMGL_00791 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPPOIMGL_00792 3.6e-58 rplQ J Ribosomal protein L17
NPPOIMGL_00793 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPPOIMGL_00794 2.2e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPPOIMGL_00795 3e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPPOIMGL_00796 2.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPPOIMGL_00797 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPPOIMGL_00798 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NPPOIMGL_00799 1.2e-143 ybaJ Q Methyltransferase domain
NPPOIMGL_00800 9.7e-66 ybaK S Protein of unknown function (DUF2521)
NPPOIMGL_00801 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPPOIMGL_00802 3.6e-152 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NPPOIMGL_00803 8.4e-47 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NPPOIMGL_00804 1.2e-84 gerD
NPPOIMGL_00805 2.1e-97 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NPPOIMGL_00806 2.5e-110 pdaB 3.5.1.104 G Polysaccharide deacetylase
NPPOIMGL_00808 7.7e-118 S Domain of unknown function, YrpD
NPPOIMGL_00810 3.6e-14 tatA U protein secretion
NPPOIMGL_00811 2.2e-21 tatA U protein secretion
NPPOIMGL_00812 6.9e-71
NPPOIMGL_00813 1.3e-78 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NPPOIMGL_00814 1.2e-50 S Protein of unknown function (DUF1433)
NPPOIMGL_00815 8.3e-244 I Pfam Lipase (class 3)
NPPOIMGL_00816 2.4e-41
NPPOIMGL_00817 1.5e-61 L Belongs to the 'phage' integrase family
NPPOIMGL_00818 3.5e-26 comP 2.7.13.3 T Histidine kinase
NPPOIMGL_00820 8.9e-63 comQ H Belongs to the FPP GGPP synthase family
NPPOIMGL_00821 4.9e-142 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
NPPOIMGL_00822 9.3e-64 K BetI-type transcriptional repressor, C-terminal
NPPOIMGL_00823 3e-97 S Phage portal protein, SPP1 Gp6-like
NPPOIMGL_00825 9.2e-56 S Domain of unknown function (DUF4355)
NPPOIMGL_00826 1.2e-123 S Phage capsid family
NPPOIMGL_00827 8.7e-48 xkdO L Transglycosylase SLT domain
NPPOIMGL_00828 5e-17
NPPOIMGL_00829 2e-39 S Phage XkdN-like tail assembly chaperone protein, TAC
NPPOIMGL_00830 9.3e-32 ps334 S Terminase-like family
NPPOIMGL_00831 2.8e-34 S Phage portal protein, SPP1 Gp6-like
NPPOIMGL_00832 5.2e-96 S Phage portal protein, SPP1 Gp6-like
NPPOIMGL_00833 6.4e-63 S Domain of unknown function (DUF4355)
NPPOIMGL_00834 1.9e-111 S Phage capsid family
NPPOIMGL_00835 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NPPOIMGL_00836 1.1e-130 yqeB
NPPOIMGL_00837 3.8e-51 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NPPOIMGL_00838 1.5e-55
NPPOIMGL_00839 8.2e-35 yxiG
NPPOIMGL_00840 4.8e-58
NPPOIMGL_00841 8.4e-84
NPPOIMGL_00842 1.5e-92 S Protein of unknown function (DUF4240)
NPPOIMGL_00843 2.5e-72
NPPOIMGL_00844 5.4e-58
NPPOIMGL_00845 9.4e-80 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NPPOIMGL_00846 2.4e-152 1.1.1.219 M NAD dependent epimerase dehydratase family
NPPOIMGL_00847 1.3e-27
NPPOIMGL_00849 1.8e-47 S Tetratricopeptide repeat
NPPOIMGL_00850 4.9e-65 phzA Q Isochorismatase family
NPPOIMGL_00851 2.1e-61
NPPOIMGL_00853 2.5e-225 amt P Ammonium transporter
NPPOIMGL_00854 1.6e-58 nrgB K Belongs to the P(II) protein family
NPPOIMGL_00855 1.3e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NPPOIMGL_00856 5.1e-72 ywnJ S VanZ like family
NPPOIMGL_00857 2e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NPPOIMGL_00858 2.6e-20 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NPPOIMGL_00859 1.7e-75 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NPPOIMGL_00860 1.9e-12 ywnC S Family of unknown function (DUF5362)
NPPOIMGL_00861 2.9e-70 ywnF S Family of unknown function (DUF5392)
NPPOIMGL_00862 3.3e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPPOIMGL_00863 5.3e-144 mta K transcriptional
NPPOIMGL_00864 2.6e-59 ywnC S Family of unknown function (DUF5362)
NPPOIMGL_00865 9e-113 ywnB S NAD(P)H-binding
NPPOIMGL_00866 1.7e-64 ywnA K Transcriptional regulator
NPPOIMGL_00867 1.7e-179 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NPPOIMGL_00868 2.1e-157 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NPPOIMGL_00869 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NPPOIMGL_00870 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NPPOIMGL_00871 1.4e-111 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NPPOIMGL_00872 6.1e-121 urtD S ATPases associated with a variety of cellular activities
NPPOIMGL_00873 1.2e-183 urtC E Belongs to the binding-protein-dependent transport system permease family
NPPOIMGL_00874 9.3e-148 urtB E Belongs to the binding-protein-dependent transport system permease family
NPPOIMGL_00875 1.2e-216 urtA E Receptor family ligand binding region
NPPOIMGL_00876 3.2e-10 csbD K CsbD-like
NPPOIMGL_00877 3e-84 ywmF S Peptidase M50
NPPOIMGL_00878 1.3e-103 S response regulator aspartate phosphatase
NPPOIMGL_00879 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NPPOIMGL_00880 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NPPOIMGL_00882 6.3e-57 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NPPOIMGL_00883 1.2e-36 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NPPOIMGL_00884 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NPPOIMGL_00885 5.6e-171 spoIID D Stage II sporulation protein D
NPPOIMGL_00886 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPPOIMGL_00887 1.2e-132 ywmB S TATA-box binding
NPPOIMGL_00888 1.3e-32 ywzB S membrane
NPPOIMGL_00889 4.8e-87 ywmA
NPPOIMGL_00890 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NPPOIMGL_00891 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPPOIMGL_00892 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPPOIMGL_00893 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPPOIMGL_00894 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPPOIMGL_00895 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPPOIMGL_00896 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPPOIMGL_00897 2.7e-122 atpB C it plays a direct role in the translocation of protons across the membrane
NPPOIMGL_00898 2.5e-62 atpI S ATP synthase
NPPOIMGL_00899 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPPOIMGL_00900 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPPOIMGL_00901 7.2e-95 ywlG S Belongs to the UPF0340 family
NPPOIMGL_00902 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NPPOIMGL_00903 1.9e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPPOIMGL_00904 2.9e-91 mntP P Probably functions as a manganese efflux pump
NPPOIMGL_00905 4.4e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPPOIMGL_00906 1e-72 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NPPOIMGL_00907 6.1e-112 spoIIR S stage II sporulation protein R
NPPOIMGL_00908 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
NPPOIMGL_00910 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPPOIMGL_00911 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPPOIMGL_00912 2.1e-64 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPPOIMGL_00913 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NPPOIMGL_00914 8.6e-160 ywkB S Membrane transport protein
NPPOIMGL_00915 0.0 sfcA 1.1.1.38 C malic enzyme
NPPOIMGL_00916 7e-104 tdk 2.7.1.21 F thymidine kinase
NPPOIMGL_00917 1.1e-32 rpmE J Binds the 23S rRNA
NPPOIMGL_00918 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NPPOIMGL_00919 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NPPOIMGL_00920 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPPOIMGL_00921 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NPPOIMGL_00922 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NPPOIMGL_00923 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NPPOIMGL_00924 1.8e-90 ywjG S Domain of unknown function (DUF2529)
NPPOIMGL_00925 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPPOIMGL_00926 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPPOIMGL_00927 6.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NPPOIMGL_00928 0.0 fadF C COG0247 Fe-S oxidoreductase
NPPOIMGL_00929 2.3e-128 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NPPOIMGL_00930 1.5e-100 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NPPOIMGL_00931 6.1e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NPPOIMGL_00932 2.7e-42 ywjC
NPPOIMGL_00933 2e-36 ywjB H RibD C-terminal domain
NPPOIMGL_00936 2.4e-11 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPPOIMGL_00937 1.1e-208 ltrA L DNA polymerase
NPPOIMGL_00938 6.7e-39
NPPOIMGL_00939 1.2e-136 3.4.24.40 CO amine dehydrogenase activity
NPPOIMGL_00940 1.7e-96 L endonuclease activity
NPPOIMGL_00943 4.3e-12 L Helix-turn-helix domain of resolvase
NPPOIMGL_00944 2.1e-137 L IstB-like ATP binding protein
NPPOIMGL_00945 2.5e-186 L Transposase
NPPOIMGL_00946 1.5e-78 T HPP family
NPPOIMGL_00947 8e-89 S CGNR zinc finger
NPPOIMGL_00949 5.3e-42
NPPOIMGL_00950 1.8e-92 xkdC L IstB-like ATP binding protein
NPPOIMGL_00952 5.3e-32 S YopX protein
NPPOIMGL_00954 8.9e-12 cwlJ 3.5.1.28 M Cell wall
NPPOIMGL_00955 6.4e-24
NPPOIMGL_00956 3.2e-77 O Hsp20/alpha crystallin family
NPPOIMGL_00957 1.1e-12 S Spore germination B3/ GerAC like, C-terminal
NPPOIMGL_00958 8.6e-31 M Peptidoglycan-binding domain 1 protein
NPPOIMGL_00959 7.9e-52 V HNH endonuclease
NPPOIMGL_00960 5.2e-93 yokH G SMI1 / KNR4 family
NPPOIMGL_00961 1.6e-136 ybbA S Putative esterase
NPPOIMGL_00962 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
NPPOIMGL_00964 9.6e-212 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NPPOIMGL_00965 8.5e-19 L Integrase core domain
NPPOIMGL_00966 1.9e-198 L COG3385 FOG Transposase and inactivated derivatives
NPPOIMGL_00968 9.5e-241 M Glycosyltransferase like family 2
NPPOIMGL_00970 1.2e-63 L Phage integrase, N-terminal SAM-like domain
NPPOIMGL_00977 7.8e-48 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NPPOIMGL_00978 6.4e-57 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NPPOIMGL_00979 1.1e-09
NPPOIMGL_00980 9.8e-36 O Glutaredoxin
NPPOIMGL_00981 6.9e-65 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPPOIMGL_00982 4.5e-86 L HNH endonuclease
NPPOIMGL_00983 7.3e-101 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPPOIMGL_00985 5.1e-203 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPPOIMGL_00986 8e-33 L GIY-YIG catalytic domain
NPPOIMGL_00987 2.6e-130 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPPOIMGL_00988 1.5e-65 S NrdI Flavodoxin like
NPPOIMGL_00992 6.6e-12 larC 4.99.1.12 FJ Protein conserved in bacteria
NPPOIMGL_00996 2.2e-10 S YopX protein
NPPOIMGL_01004 1.2e-25 S hydrolase activity
NPPOIMGL_01010 2.5e-161 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
NPPOIMGL_01011 9.6e-18 S C-5 cytosine-specific DNA methylase
NPPOIMGL_01012 7.2e-70 S C-5 cytosine-specific DNA methylase
NPPOIMGL_01014 1.7e-66 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
NPPOIMGL_01017 4.3e-23 S protein conserved in bacteria
NPPOIMGL_01018 4e-293 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
NPPOIMGL_01019 1.6e-170 S PD-(D/E)XK nuclease superfamily
NPPOIMGL_01020 2.7e-148 3.6.4.12 L DNA primase activity
NPPOIMGL_01021 3.6e-242 3.6.4.12 L DnaB-like helicase C terminal domain
NPPOIMGL_01023 5e-159 S AAA domain
NPPOIMGL_01024 2.3e-165
NPPOIMGL_01028 1.2e-38 M Parallel beta-helix repeats
NPPOIMGL_01030 2.2e-189
NPPOIMGL_01032 1e-127 yoqW S Belongs to the SOS response-associated peptidase family
NPPOIMGL_01033 2.4e-147 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
NPPOIMGL_01034 2e-73
NPPOIMGL_01035 4.5e-19 S Hypothetical protein (DUF2513)
NPPOIMGL_01037 1.3e-56
NPPOIMGL_01042 1.4e-95 S Protein of unknown function (DUF1273)
NPPOIMGL_01047 8e-65
NPPOIMGL_01053 3.2e-10 S YopX protein
NPPOIMGL_01054 1.4e-41
NPPOIMGL_01058 1.8e-15 K Transcriptional regulator
NPPOIMGL_01059 5.3e-32
NPPOIMGL_01060 3.3e-250
NPPOIMGL_01061 5.8e-40 L Belongs to the 'phage' integrase family
NPPOIMGL_01067 2.5e-81
NPPOIMGL_01069 1.4e-15
NPPOIMGL_01070 1.5e-20
NPPOIMGL_01074 3.8e-37 S Protein conserved in bacteria
NPPOIMGL_01079 1.4e-31 K Cro/C1-type HTH DNA-binding domain
NPPOIMGL_01080 2.8e-20
NPPOIMGL_01083 1.2e-69 Q Collagen triple helix repeat (20 copies)
NPPOIMGL_01084 4.4e-32 V ABC transporter, ATP-binding protein
NPPOIMGL_01085 1.1e-122 V ABC transporter, ATP-binding protein
NPPOIMGL_01086 4.8e-45 KT LuxR family transcriptional regulator
NPPOIMGL_01087 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
NPPOIMGL_01088 8.4e-54 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NPPOIMGL_01090 2.1e-13 K Transcriptional regulator
NPPOIMGL_01093 6.2e-22 S Inner spore coat protein D
NPPOIMGL_01096 3.5e-73 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NPPOIMGL_01097 6.3e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NPPOIMGL_01098 6.3e-57 arsR K transcriptional
NPPOIMGL_01100 1.4e-87 xkdO L Transglycosylase SLT domain
NPPOIMGL_01101 9.1e-53 S Phage XkdN-like tail assembly chaperone protein, TAC
NPPOIMGL_01102 1e-207
NPPOIMGL_01103 2.3e-22
NPPOIMGL_01104 3.1e-70 M nucleic acid phosphodiester bond hydrolysis
NPPOIMGL_01105 5.7e-181 M nucleic acid phosphodiester bond hydrolysis
NPPOIMGL_01107 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
NPPOIMGL_01108 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NPPOIMGL_01109 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPPOIMGL_01110 4.1e-30 yazB K transcriptional
NPPOIMGL_01111 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NPPOIMGL_01112 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NPPOIMGL_01113 8.7e-40 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NPPOIMGL_01114 5.5e-72 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NPPOIMGL_01115 1e-31 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NPPOIMGL_01116 2e-20 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NPPOIMGL_01117 6.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NPPOIMGL_01118 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NPPOIMGL_01119 1.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NPPOIMGL_01120 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPPOIMGL_01121 2e-158 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NPPOIMGL_01122 6.4e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPPOIMGL_01123 2.7e-141 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NPPOIMGL_01124 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPPOIMGL_01125 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPPOIMGL_01126 1.9e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPPOIMGL_01127 3.7e-185 KLT serine threonine protein kinase
NPPOIMGL_01128 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NPPOIMGL_01129 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NPPOIMGL_01132 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NPPOIMGL_01133 1.1e-44 divIC D Septum formation initiator
NPPOIMGL_01134 2.1e-106 yabQ S spore cortex biosynthesis protein
NPPOIMGL_01135 1.5e-49 yabP S Sporulation protein YabP
NPPOIMGL_01136 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NPPOIMGL_01137 9.5e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NPPOIMGL_01138 9.3e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPPOIMGL_01139 1.5e-92 spoVT K stage V sporulation protein
NPPOIMGL_01140 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPPOIMGL_01141 2.2e-53 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPPOIMGL_01142 7.9e-302 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPPOIMGL_01143 2.4e-39 yabK S Peptide ABC transporter permease
NPPOIMGL_01144 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPPOIMGL_01145 6.6e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NPPOIMGL_01146 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPPOIMGL_01147 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPPOIMGL_01148 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NPPOIMGL_01149 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NPPOIMGL_01150 1.6e-139 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NPPOIMGL_01151 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NPPOIMGL_01152 2e-26 sspF S DNA topological change
NPPOIMGL_01153 7.8e-39 veg S protein conserved in bacteria
NPPOIMGL_01154 1.6e-136 yabG S peptidase
NPPOIMGL_01155 1.5e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPPOIMGL_01156 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPPOIMGL_01157 1e-104 rpfB GH23 T protein conserved in bacteria
NPPOIMGL_01158 2.1e-48 rpfB GH23 T protein conserved in bacteria
NPPOIMGL_01159 1.8e-110 tatD L hydrolase, TatD
NPPOIMGL_01160 3.9e-176 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPPOIMGL_01161 7.3e-101 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPPOIMGL_01162 9.2e-115 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPPOIMGL_01163 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NPPOIMGL_01164 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPPOIMGL_01165 1.5e-49 yazA L endonuclease containing a URI domain
NPPOIMGL_01166 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NPPOIMGL_01167 4.8e-31 yabA L Involved in initiation control of chromosome replication
NPPOIMGL_01168 6.1e-146 yaaT S stage 0 sporulation protein
NPPOIMGL_01169 2.1e-177 holB 2.7.7.7 L DNA polymerase III
NPPOIMGL_01170 1.5e-71 yaaR S protein conserved in bacteria
NPPOIMGL_01171 2.2e-54 yaaQ S protein conserved in bacteria
NPPOIMGL_01172 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPPOIMGL_01173 1.9e-217 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NPPOIMGL_01174 7.4e-24 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NPPOIMGL_01175 7.8e-19 yaaN P Belongs to the TelA family
NPPOIMGL_01176 1.3e-171 yaaN P Belongs to the TelA family
NPPOIMGL_01177 5.8e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NPPOIMGL_01178 3.4e-31 csfB S Inhibitor of sigma-G Gin
NPPOIMGL_01179 2.5e-29 S response regulator aspartate phosphatase
NPPOIMGL_01180 2.6e-35 yjcS S Antibiotic biosynthesis monooxygenase
NPPOIMGL_01181 4e-45 yjcN
NPPOIMGL_01183 4.1e-40
NPPOIMGL_01184 1.9e-124 yobL S Bacterial EndoU nuclease
NPPOIMGL_01185 1.4e-74 yvmB K helix_turn_helix multiple antibiotic resistance protein
NPPOIMGL_01186 1.5e-196 yvmA EGP Major facilitator Superfamily
NPPOIMGL_01187 3.1e-41
NPPOIMGL_01188 1.3e-150 P ABC-2 family transporter protein
NPPOIMGL_01189 7.9e-117 ytrB P abc transporter atp-binding protein
NPPOIMGL_01190 9.3e-16 yqaO S Phage-like element PBSX protein XtrA
NPPOIMGL_01195 5.4e-50
NPPOIMGL_01196 8.4e-109 yobL S Bacterial EndoU nuclease
NPPOIMGL_01197 6.2e-50 S Aspartate phosphatase response regulator
NPPOIMGL_01198 1.9e-81 S Aspartate phosphatase response regulator
NPPOIMGL_01200 2.2e-96 msbA2 3.6.3.44 V ABC transporter
NPPOIMGL_01202 1.8e-220 L Transposase
NPPOIMGL_01203 3.2e-117 L PhoH-like protein
NPPOIMGL_01204 7.5e-175 yisQ V Mate efflux family protein
NPPOIMGL_01205 5.4e-53 yisQ V Mate efflux family protein
NPPOIMGL_01206 1.2e-160 yisR K Transcriptional regulator
NPPOIMGL_01207 6.9e-184 purR K helix_turn _helix lactose operon repressor
NPPOIMGL_01208 1.4e-31 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NPPOIMGL_01209 3.9e-124 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NPPOIMGL_01210 9.1e-92 yisT S DinB family
NPPOIMGL_01211 2.7e-106 argO S Lysine exporter protein LysE YggA
NPPOIMGL_01212 4.8e-279 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPPOIMGL_01213 1.7e-31 mcbG S Pentapeptide repeats (9 copies)
NPPOIMGL_01214 4.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPPOIMGL_01215 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NPPOIMGL_01216 1.9e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NPPOIMGL_01217 1.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NPPOIMGL_01218 5.3e-119 comB 3.1.3.71 H Belongs to the ComB family
NPPOIMGL_01219 5.4e-141 yitD 4.4.1.19 S synthase
NPPOIMGL_01220 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPPOIMGL_01221 1.6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NPPOIMGL_01222 2.6e-228 yitG EGP Major facilitator Superfamily
NPPOIMGL_01223 1.3e-148 yitH K Acetyltransferase (GNAT) domain
NPPOIMGL_01224 1e-70 yjcF S Acetyltransferase (GNAT) domain
NPPOIMGL_01225 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NPPOIMGL_01226 8.6e-55 yajQ S Belongs to the UPF0234 family
NPPOIMGL_01227 2e-160 cvfB S protein conserved in bacteria
NPPOIMGL_01228 8.5e-94
NPPOIMGL_01229 1.4e-170
NPPOIMGL_01230 1.5e-97 S Sporulation delaying protein SdpA
NPPOIMGL_01231 1.5e-58 K Transcriptional regulator PadR-like family
NPPOIMGL_01232 1e-94
NPPOIMGL_01233 1.4e-44 yitR S Domain of unknown function (DUF3784)
NPPOIMGL_01234 2.7e-307 nprB 3.4.24.28 E Peptidase M4
NPPOIMGL_01235 9e-36 yitR S Domain of unknown function (DUF3784)
NPPOIMGL_01236 3.5e-157 yitS S protein conserved in bacteria
NPPOIMGL_01237 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NPPOIMGL_01238 5e-73 ipi S Intracellular proteinase inhibitor
NPPOIMGL_01239 1.5e-26 S Protein of unknown function (DUF3813)
NPPOIMGL_01241 4.1e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NPPOIMGL_01242 2.9e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NPPOIMGL_01243 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NPPOIMGL_01244 3.3e-22 pilT S Proteolipid membrane potential modulator
NPPOIMGL_01245 2.7e-266 yitY C D-arabinono-1,4-lactone oxidase
NPPOIMGL_01246 1.7e-88 norB G Major Facilitator Superfamily
NPPOIMGL_01247 1.3e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NPPOIMGL_01248 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NPPOIMGL_01249 9.2e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NPPOIMGL_01250 2.4e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NPPOIMGL_01251 1.5e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPPOIMGL_01252 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NPPOIMGL_01253 1.9e-223 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NPPOIMGL_01254 5.1e-20 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPPOIMGL_01255 7.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPPOIMGL_01256 9.5e-28 yjzC S YjzC-like protein
NPPOIMGL_01257 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NPPOIMGL_01258 6.2e-142 yjaU I carboxylic ester hydrolase activity
NPPOIMGL_01259 9.1e-95 yjaV
NPPOIMGL_01260 2.5e-183 med S Transcriptional activator protein med
NPPOIMGL_01261 7.3e-26 comZ S ComZ
NPPOIMGL_01262 5e-21 yjzB
NPPOIMGL_01263 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPPOIMGL_01264 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPPOIMGL_01265 2.8e-148 yjaZ O Zn-dependent protease
NPPOIMGL_01266 5.1e-184 appD P Belongs to the ABC transporter superfamily
NPPOIMGL_01267 1.1e-52 yetL K helix_turn_helix multiple antibiotic resistance protein
NPPOIMGL_01268 7.5e-153 yetK EG EamA-like transporter family
NPPOIMGL_01269 2.7e-31 xhlB S SPP1 phage holin
NPPOIMGL_01270 1.4e-28 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NPPOIMGL_01271 1.4e-25 M Peptidoglycan-binding domain 1 protein
NPPOIMGL_01272 8.4e-37 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPPOIMGL_01273 1.5e-42 S YolD-like protein
NPPOIMGL_01274 5.2e-167 L Recombinase
NPPOIMGL_01275 3e-84 yfkR S spore germination
NPPOIMGL_01277 3.5e-82 S SMI1-KNR4 cell-wall
NPPOIMGL_01278 5.5e-119 EGP Necrosis inducing protein (NPP1)
NPPOIMGL_01279 5.7e-65 A Pre-toxin TG
NPPOIMGL_01280 1.3e-97 S Suppressor of fused protein (SUFU)
NPPOIMGL_01281 1.2e-32
NPPOIMGL_01282 3.6e-26 L COG1112 Superfamily I DNA and RNA helicases and helicase subunits
NPPOIMGL_01283 3.5e-59 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NPPOIMGL_01284 8.1e-92 L HKD family nuclease
NPPOIMGL_01285 2.4e-74
NPPOIMGL_01286 1.1e-10
NPPOIMGL_01288 3.8e-144 L nucleic acid phosphodiester bond hydrolysis
NPPOIMGL_01289 1.4e-18 yqaF K Helix-turn-helix XRE-family like proteins
NPPOIMGL_01293 1.4e-70 J Acetyltransferase (GNAT) domain
NPPOIMGL_01294 2.4e-98 padR K transcriptional
NPPOIMGL_01295 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NPPOIMGL_01296 1.7e-172 L COG3436 Transposase and inactivated derivatives
NPPOIMGL_01297 1.7e-182 E Hydrolase CocE NonD family
NPPOIMGL_01298 7.4e-126 S X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
NPPOIMGL_01300 2.2e-14 K dihydroxyacetone kinase regulator
NPPOIMGL_01301 7.2e-21 K dihydroxyacetone kinase regulator
NPPOIMGL_01302 6.5e-19 K transcriptional regulator
NPPOIMGL_01304 8.7e-113 yhzB S B3/4 domain
NPPOIMGL_01305 6e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NPPOIMGL_01306 4.8e-176 yhbB S Putative amidase domain
NPPOIMGL_01307 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPPOIMGL_01308 1.5e-101 yhbD K Protein of unknown function (DUF4004)
NPPOIMGL_01309 1.4e-58 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NPPOIMGL_01310 1.4e-69 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NPPOIMGL_01311 0.0 prkA T Ser protein kinase
NPPOIMGL_01312 2.5e-225 yhbH S Belongs to the UPF0229 family
NPPOIMGL_01313 2.2e-76 yhbI K DNA-binding transcription factor activity
NPPOIMGL_01314 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NPPOIMGL_01315 3.1e-271 yhcA EGP Major facilitator Superfamily
NPPOIMGL_01316 5.2e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NPPOIMGL_01317 2.8e-37 yhcC
NPPOIMGL_01318 2.3e-54
NPPOIMGL_01319 1.9e-59 yhcF K Transcriptional regulator
NPPOIMGL_01320 4e-122 yhcG V ABC transporter, ATP-binding protein
NPPOIMGL_01321 2.2e-165 yhcH V ABC transporter, ATP-binding protein
NPPOIMGL_01322 8.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPPOIMGL_01323 1e-30 cspB K Cold-shock protein
NPPOIMGL_01324 8.3e-151 metQ M Belongs to the nlpA lipoprotein family
NPPOIMGL_01325 7.3e-95 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NPPOIMGL_01326 1.1e-107 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NPPOIMGL_01327 2e-184 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPPOIMGL_01328 2.1e-36 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPPOIMGL_01329 5.7e-40 yhcM
NPPOIMGL_01330 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPPOIMGL_01331 5.6e-167 yhcP
NPPOIMGL_01332 1.5e-99 yhcQ M Spore coat protein
NPPOIMGL_01333 6.5e-22 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NPPOIMGL_01334 1.4e-55 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NPPOIMGL_01335 3.6e-65 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NPPOIMGL_01336 4.1e-127 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NPPOIMGL_01337 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NPPOIMGL_01338 3.2e-20 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NPPOIMGL_01339 3.5e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NPPOIMGL_01340 3e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPPOIMGL_01341 2.1e-67 yhcU S Family of unknown function (DUF5365)
NPPOIMGL_01342 9.9e-68 yhcV S COG0517 FOG CBS domain
NPPOIMGL_01343 2.3e-119 yhcW 5.4.2.6 S hydrolase
NPPOIMGL_01344 1.7e-273 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NPPOIMGL_01345 1e-259 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPPOIMGL_01346 1.2e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NPPOIMGL_01347 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NPPOIMGL_01348 4.3e-208 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPPOIMGL_01349 4e-78 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPPOIMGL_01350 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NPPOIMGL_01351 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NPPOIMGL_01352 3.5e-204 yhcY 2.7.13.3 T Histidine kinase
NPPOIMGL_01353 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPPOIMGL_01354 3.6e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
NPPOIMGL_01355 1.2e-38 yhdB S YhdB-like protein
NPPOIMGL_01356 2e-52 yhdC S Protein of unknown function (DUF3889)
NPPOIMGL_01357 1.7e-122 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NPPOIMGL_01358 2.2e-45 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NPPOIMGL_01359 6.9e-66 nsrR K Transcriptional regulator
NPPOIMGL_01360 2.1e-237 ygxB M Conserved TM helix
NPPOIMGL_01361 2.1e-276 ycgB S Stage V sporulation protein R
NPPOIMGL_01362 3.2e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NPPOIMGL_01363 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NPPOIMGL_01364 3.8e-162 citR K Transcriptional regulator
NPPOIMGL_01365 2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
NPPOIMGL_01366 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_01367 3.4e-250 yhdG E amino acid
NPPOIMGL_01368 7.4e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NPPOIMGL_01369 7.4e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPPOIMGL_01370 2.2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPPOIMGL_01371 8.1e-45 yhdK S Sigma-M inhibitor protein
NPPOIMGL_01372 6.6e-201 yhdL S Sigma factor regulator N-terminal
NPPOIMGL_01373 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_01374 1.7e-190 yhdN C Aldo keto reductase
NPPOIMGL_01375 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NPPOIMGL_01376 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NPPOIMGL_01377 4.7e-74 cueR K transcriptional
NPPOIMGL_01378 2e-222 yhdR 2.6.1.1 E Aminotransferase
NPPOIMGL_01379 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NPPOIMGL_01380 7.1e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPPOIMGL_01381 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPPOIMGL_01382 8.9e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPPOIMGL_01384 1.4e-182 yhdY M Mechanosensitive ion channel
NPPOIMGL_01385 8.9e-41 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NPPOIMGL_01386 6.4e-90 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NPPOIMGL_01387 6.3e-146 yheN G deacetylase
NPPOIMGL_01388 9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NPPOIMGL_01389 8.6e-230 nhaC C Na H antiporter
NPPOIMGL_01390 7.6e-84 nhaX T Belongs to the universal stress protein A family
NPPOIMGL_01391 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPPOIMGL_01392 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPPOIMGL_01393 1.7e-108 yheG GM NAD(P)H-binding
NPPOIMGL_01394 4.1e-27 sspB S spore protein
NPPOIMGL_01395 1.3e-36 yheE S Family of unknown function (DUF5342)
NPPOIMGL_01396 9.7e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NPPOIMGL_01397 4.3e-216 yheC HJ YheC/D like ATP-grasp
NPPOIMGL_01398 1.1e-201 yheB S Belongs to the UPF0754 family
NPPOIMGL_01399 9.5e-48 yheA S Belongs to the UPF0342 family
NPPOIMGL_01400 1.9e-203 yhaZ L DNA alkylation repair enzyme
NPPOIMGL_01401 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NPPOIMGL_01402 1.5e-291 hemZ H coproporphyrinogen III oxidase
NPPOIMGL_01403 6.3e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NPPOIMGL_01404 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NPPOIMGL_01406 5.5e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
NPPOIMGL_01407 2.4e-26 S YhzD-like protein
NPPOIMGL_01408 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
NPPOIMGL_01409 6.9e-27 yhaQ S ABC transporter, ATP-binding protein
NPPOIMGL_01410 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NPPOIMGL_01411 1.8e-207 yhaO L DNA repair exonuclease
NPPOIMGL_01412 4.6e-158 yhaN L AAA domain
NPPOIMGL_01413 9.5e-309 yhaN L AAA domain
NPPOIMGL_01414 5.6e-89 yhaN L AAA domain
NPPOIMGL_01415 5.8e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NPPOIMGL_01416 1.6e-21 yhaL S Sporulation protein YhaL
NPPOIMGL_01417 1.5e-107 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPPOIMGL_01418 2e-83 yhaK S Putative zincin peptidase
NPPOIMGL_01419 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NPPOIMGL_01420 1e-113 hpr K Negative regulator of protease production and sporulation
NPPOIMGL_01421 7e-39 yhaH S YtxH-like protein
NPPOIMGL_01422 3.6e-80 trpP S Tryptophan transporter TrpP
NPPOIMGL_01423 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NPPOIMGL_01424 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NPPOIMGL_01425 8.8e-136 ecsA V transporter (ATP-binding protein)
NPPOIMGL_01426 2.9e-213 ecsB U ABC transporter
NPPOIMGL_01427 3.4e-113 ecsC S EcsC protein family
NPPOIMGL_01428 4.1e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NPPOIMGL_01429 3.5e-231 yhfA C membrane
NPPOIMGL_01430 1.7e-32 1.15.1.2 C Rubrerythrin
NPPOIMGL_01431 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NPPOIMGL_01432 3.4e-291 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPPOIMGL_01433 1.5e-126 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPPOIMGL_01434 2.4e-152 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NPPOIMGL_01435 2.3e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NPPOIMGL_01436 5e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NPPOIMGL_01437 5.4e-101 yhgD K Transcriptional regulator
NPPOIMGL_01438 4.4e-94 yhgE S YhgE Pip N-terminal domain protein
NPPOIMGL_01439 4e-108 yhgE S YhgE Pip N-terminal domain protein
NPPOIMGL_01440 7.6e-42 yhgE S YhgE Pip N-terminal domain protein
NPPOIMGL_01441 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPPOIMGL_01442 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
NPPOIMGL_01443 6.9e-149 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NPPOIMGL_01444 1.1e-55 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NPPOIMGL_01445 8.5e-66 3.4.13.21 S ASCH
NPPOIMGL_01446 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPPOIMGL_01447 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NPPOIMGL_01448 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NPPOIMGL_01449 1.9e-110 yhfK GM NmrA-like family
NPPOIMGL_01450 5.9e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NPPOIMGL_01451 1.4e-63 yhfM
NPPOIMGL_01452 9.5e-234 yhfN 3.4.24.84 O Peptidase M48
NPPOIMGL_01453 2.6e-55 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NPPOIMGL_01454 2.8e-152 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NPPOIMGL_01455 2.6e-74 VY92_01935 K acetyltransferase
NPPOIMGL_01456 1.8e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
NPPOIMGL_01457 7.4e-159 yfmC M Periplasmic binding protein
NPPOIMGL_01458 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NPPOIMGL_01459 2.1e-133 vraB 2.3.1.9 I Belongs to the thiolase family
NPPOIMGL_01460 5e-72 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NPPOIMGL_01461 2.3e-240 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NPPOIMGL_01462 7.2e-90 bioY S BioY family
NPPOIMGL_01463 1e-182 hemAT NT chemotaxis protein
NPPOIMGL_01464 8e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NPPOIMGL_01465 4.3e-81 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_01466 5e-63 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_01467 1.3e-32 yhzC S IDEAL
NPPOIMGL_01468 4.2e-109 comK K Competence transcription factor
NPPOIMGL_01469 2.3e-168 IQ Enoyl-(Acyl carrier protein) reductase
NPPOIMGL_01470 8.1e-39 yhjA S Excalibur calcium-binding domain
NPPOIMGL_01471 4e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPPOIMGL_01472 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NPPOIMGL_01473 6.7e-60 yhjD
NPPOIMGL_01474 9.1e-110 yhjE S SNARE associated Golgi protein
NPPOIMGL_01475 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NPPOIMGL_01476 2.8e-58 yhjG CH FAD binding domain
NPPOIMGL_01477 1e-231 yhjG CH FAD binding domain
NPPOIMGL_01478 4.7e-91 yhjH K helix_turn_helix multiple antibiotic resistance protein
NPPOIMGL_01481 7.2e-212 glcP G Major Facilitator Superfamily
NPPOIMGL_01482 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NPPOIMGL_01483 3.8e-159 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NPPOIMGL_01484 5.4e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NPPOIMGL_01485 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
NPPOIMGL_01486 3.7e-194 abrB S membrane
NPPOIMGL_01487 5.2e-132 EGP Transmembrane secretion effector
NPPOIMGL_01488 1.4e-69 EGP Transmembrane secretion effector
NPPOIMGL_01489 0.0 S Sugar transport-related sRNA regulator N-term
NPPOIMGL_01490 2.2e-78 yhjR S Rubrerythrin
NPPOIMGL_01491 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NPPOIMGL_01492 1.1e-225 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NPPOIMGL_01493 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NPPOIMGL_01494 3.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NPPOIMGL_01495 2.6e-299 sbcC L COG0419 ATPase involved in DNA repair
NPPOIMGL_01496 8.5e-134 sbcC L COG0419 ATPase involved in DNA repair
NPPOIMGL_01497 2.5e-49 yisB V COG1403 Restriction endonuclease
NPPOIMGL_01498 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NPPOIMGL_01499 5.3e-63 gerPE S Spore germination protein GerPE
NPPOIMGL_01500 1.1e-23 gerPD S Spore germination protein
NPPOIMGL_01501 5.3e-54 gerPC S Spore germination protein
NPPOIMGL_01502 4e-34 gerPB S cell differentiation
NPPOIMGL_01503 1.9e-33 gerPA S Spore germination protein
NPPOIMGL_01504 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NPPOIMGL_01505 3.8e-158 cotH M Spore Coat
NPPOIMGL_01506 2.7e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NPPOIMGL_01507 6.6e-57 yisL S UPF0344 protein
NPPOIMGL_01508 0.0 wprA O Belongs to the peptidase S8 family
NPPOIMGL_01509 2.4e-101 yisN S Protein of unknown function (DUF2777)
NPPOIMGL_01510 3e-198 asnO 6.3.5.4 E Asparagine synthase
NPPOIMGL_01511 4.3e-129 asnO 6.3.5.4 E Asparagine synthase
NPPOIMGL_01512 2.2e-99 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NPPOIMGL_01514 3e-16 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPPOIMGL_01515 5.5e-75 ygaO
NPPOIMGL_01516 4.4e-29 K Transcriptional regulator
NPPOIMGL_01517 9.6e-212 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NPPOIMGL_01519 9e-93 H Methionine biosynthesis protein MetW
NPPOIMGL_01520 9.8e-94 M Glycosyltransferase like family
NPPOIMGL_01524 2.9e-08 S Cro/C1-type HTH DNA-binding domain
NPPOIMGL_01525 1.2e-238 L COG3328 Transposase and inactivated derivatives
NPPOIMGL_01526 4.2e-57 L Transposase C of IS166 homeodomain
NPPOIMGL_01527 1.2e-28 L transposase activity
NPPOIMGL_01529 3.9e-69 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NPPOIMGL_01532 3.5e-19 K Cro/C1-type HTH DNA-binding domain
NPPOIMGL_01533 7.2e-144
NPPOIMGL_01534 1.2e-116 P ABC-2 family transporter protein
NPPOIMGL_01535 9.4e-33 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NPPOIMGL_01536 2.3e-30 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPPOIMGL_01537 1.1e-235 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPPOIMGL_01538 3.7e-48 ywcB S Protein of unknown function, DUF485
NPPOIMGL_01540 1.1e-121 ywcC K transcriptional regulator
NPPOIMGL_01541 9.5e-60 gtcA S GtrA-like protein
NPPOIMGL_01542 3.8e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPPOIMGL_01543 5.9e-18 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NPPOIMGL_01544 9.9e-280 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NPPOIMGL_01545 1e-35 ywzA S membrane
NPPOIMGL_01546 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NPPOIMGL_01547 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NPPOIMGL_01548 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NPPOIMGL_01549 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NPPOIMGL_01550 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NPPOIMGL_01551 8.6e-202 rodA D Belongs to the SEDS family
NPPOIMGL_01552 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NPPOIMGL_01553 7.4e-98 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPPOIMGL_01554 3e-75 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPPOIMGL_01555 0.0 vpr O Belongs to the peptidase S8 family
NPPOIMGL_01557 4.7e-62 sacT K transcriptional antiterminator
NPPOIMGL_01558 1.8e-122 sacT K transcriptional antiterminator
NPPOIMGL_01559 4.4e-55 focA P Formate/nitrite transporter
NPPOIMGL_01560 3.7e-64 focA P Formate/nitrite transporter
NPPOIMGL_01561 3.2e-245 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPPOIMGL_01562 5.3e-236 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NPPOIMGL_01563 1.2e-60 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NPPOIMGL_01564 2e-28 ywdA
NPPOIMGL_01565 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NPPOIMGL_01566 1.3e-57 pex K Transcriptional regulator PadR-like family
NPPOIMGL_01567 2.9e-111 ywdD
NPPOIMGL_01569 1.6e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
NPPOIMGL_01570 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPPOIMGL_01571 7.1e-109 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NPPOIMGL_01572 8.1e-51 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NPPOIMGL_01573 8.6e-101 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NPPOIMGL_01574 5.7e-33 ywdI S Family of unknown function (DUF5327)
NPPOIMGL_01575 1.1e-237 ywdJ F Xanthine uracil
NPPOIMGL_01576 4.3e-59 ywdK S small membrane protein
NPPOIMGL_01577 6.3e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NPPOIMGL_01578 3.4e-143 spsA M Spore Coat
NPPOIMGL_01579 4.3e-269 spsB M Capsule polysaccharide biosynthesis protein
NPPOIMGL_01580 1.8e-223 spsC E Belongs to the DegT DnrJ EryC1 family
NPPOIMGL_01581 7.5e-163 spsD 2.3.1.210 K Spore Coat
NPPOIMGL_01582 3.5e-213 spsE 2.5.1.56 M acid synthase
NPPOIMGL_01583 9.7e-132 spsF M Spore Coat
NPPOIMGL_01584 3.6e-188 spsG M Spore Coat
NPPOIMGL_01585 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NPPOIMGL_01586 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NPPOIMGL_01587 4.9e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NPPOIMGL_01588 1.3e-86 spsL 5.1.3.13 M Spore Coat
NPPOIMGL_01589 2.7e-24
NPPOIMGL_01590 6.4e-76
NPPOIMGL_01591 1.7e-230 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NPPOIMGL_01592 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NPPOIMGL_01593 0.0 rocB E arginine degradation protein
NPPOIMGL_01594 5.7e-261 lysP E amino acid
NPPOIMGL_01595 1e-166 ywfA EGP Major facilitator Superfamily
NPPOIMGL_01596 2.2e-55 ywfA EGP Major facilitator Superfamily
NPPOIMGL_01597 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NPPOIMGL_01598 3.7e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NPPOIMGL_01599 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_01600 4.7e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NPPOIMGL_01601 8.6e-210 bacE EGP Major facilitator Superfamily
NPPOIMGL_01602 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
NPPOIMGL_01603 6.4e-137 IQ Enoyl-(Acyl carrier protein) reductase
NPPOIMGL_01604 1.1e-146 ywfI C May function as heme-dependent peroxidase
NPPOIMGL_01605 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NPPOIMGL_01606 1.1e-156 cysL K Transcriptional regulator
NPPOIMGL_01607 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NPPOIMGL_01608 1.6e-129 ywfM EG EamA-like transporter family
NPPOIMGL_01609 4e-91 rsfA_1
NPPOIMGL_01610 2.4e-34 rsfA_1
NPPOIMGL_01611 3.1e-36 ywzC S Belongs to the UPF0741 family
NPPOIMGL_01612 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
NPPOIMGL_01613 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NPPOIMGL_01614 6.2e-79 yffB K Transcriptional regulator
NPPOIMGL_01615 9.3e-226 mmr U Major Facilitator Superfamily
NPPOIMGL_01617 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPPOIMGL_01618 3.3e-71 ywhA K Transcriptional regulator
NPPOIMGL_01619 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NPPOIMGL_01620 6.2e-82 ywhC S Peptidase family M50
NPPOIMGL_01621 1.6e-74 ywhC S Peptidase family M50
NPPOIMGL_01623 2e-94 ywhD S YwhD family
NPPOIMGL_01624 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPPOIMGL_01625 1.6e-61 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NPPOIMGL_01626 8.9e-92 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NPPOIMGL_01627 1.5e-29 speB 3.5.3.11 E Belongs to the arginase family
NPPOIMGL_01628 1.4e-130 speB 3.5.3.11 E Belongs to the arginase family
NPPOIMGL_01629 1.2e-16 ywhH S Aminoacyl-tRNA editing domain
NPPOIMGL_01630 7.8e-12 ywhH S Cys-tRNA(Pro) hydrolase activity
NPPOIMGL_01632 1.1e-34 S response regulator aspartate phosphatase
NPPOIMGL_01634 6.8e-79 S aspartate phosphatase
NPPOIMGL_01635 6e-191 ywhK CO amine dehydrogenase activity
NPPOIMGL_01636 7.2e-225 ywhL CO amine dehydrogenase activity
NPPOIMGL_01638 1.3e-248 L Peptidase, M16
NPPOIMGL_01639 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
NPPOIMGL_01640 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NPPOIMGL_01641 3.3e-132 cbiO V ABC transporter
NPPOIMGL_01643 1.4e-262 C Fe-S oxidoreductases
NPPOIMGL_01644 1e-07 S Bacteriocin subtilosin A
NPPOIMGL_01645 4.7e-73 ywiB S protein conserved in bacteria
NPPOIMGL_01646 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NPPOIMGL_01647 2.3e-213 narK P COG2223 Nitrate nitrite transporter
NPPOIMGL_01648 5.9e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NPPOIMGL_01649 2.3e-130 ywiC S YwiC-like protein
NPPOIMGL_01650 7e-86 arfM T cyclic nucleotide binding
NPPOIMGL_01651 1.7e-80 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPPOIMGL_01652 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPPOIMGL_01653 1.4e-135 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPPOIMGL_01654 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
NPPOIMGL_01655 3.6e-94 narJ 1.7.5.1 C nitrate reductase
NPPOIMGL_01656 8.9e-91 narI 1.7.5.1 C nitrate reductase, gamma
NPPOIMGL_01657 7.9e-20 narI 1.7.5.1 C nitrate reductase, gamma
NPPOIMGL_01658 4.2e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPPOIMGL_01659 7.4e-211 ywjA V ABC transporter
NPPOIMGL_01660 9.1e-133 ywjA V ABC transporter
NPPOIMGL_01661 1e-41
NPPOIMGL_01662 1.8e-165 yxxF EG EamA-like transporter family
NPPOIMGL_01663 2.9e-53 L COG3385 FOG Transposase and inactivated derivatives
NPPOIMGL_01664 6.7e-90 L COG3385 FOG Transposase and inactivated derivatives
NPPOIMGL_01665 5e-09 S AAA domain
NPPOIMGL_01667 6.2e-104 V Domain of unknown function (DUF3578)
NPPOIMGL_01668 2.8e-128 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NPPOIMGL_01669 3.2e-125 S Phosphotransferase enzyme family
NPPOIMGL_01672 4e-27 S Protein of unknown function (DUF1433)
NPPOIMGL_01673 4e-31 S Protein of unknown function (DUF1433)
NPPOIMGL_01674 1.5e-117 aacC 2.3.1.81 V aminoglycoside
NPPOIMGL_01675 1.8e-38 S Protein of unknown function (DUF1643)
NPPOIMGL_01676 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NPPOIMGL_01677 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NPPOIMGL_01678 2.9e-196 gerM S COG5401 Spore germination protein
NPPOIMGL_01679 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NPPOIMGL_01680 2.2e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPPOIMGL_01681 1.4e-92 ysnB S Phosphoesterase
NPPOIMGL_01683 1.9e-73 ysnF S protein conserved in bacteria
NPPOIMGL_01684 3.8e-58 ysnF S protein conserved in bacteria
NPPOIMGL_01685 4e-75 ysnE K acetyltransferase
NPPOIMGL_01686 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NPPOIMGL_01687 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NPPOIMGL_01688 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NPPOIMGL_01689 9.3e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NPPOIMGL_01690 2.2e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NPPOIMGL_01691 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPPOIMGL_01692 4.3e-73 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPPOIMGL_01693 4.6e-38 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPPOIMGL_01694 4.8e-41 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NPPOIMGL_01695 5.1e-187 ysoA H Tetratricopeptide repeat
NPPOIMGL_01696 1.6e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPPOIMGL_01697 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPPOIMGL_01698 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NPPOIMGL_01699 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NPPOIMGL_01700 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NPPOIMGL_01701 4.1e-89 ysxD
NPPOIMGL_01702 1.3e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NPPOIMGL_01703 3.6e-146 hemX O cytochrome C
NPPOIMGL_01704 1.1e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NPPOIMGL_01705 7.9e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NPPOIMGL_01706 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
NPPOIMGL_01707 1.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NPPOIMGL_01708 1.9e-143 spoVID M stage VI sporulation protein D
NPPOIMGL_01709 2.3e-54 spoVID M stage VI sporulation protein D
NPPOIMGL_01710 6.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NPPOIMGL_01711 1.6e-25
NPPOIMGL_01712 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPPOIMGL_01713 2.2e-160 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPPOIMGL_01714 1.2e-70 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPPOIMGL_01715 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NPPOIMGL_01716 1.7e-61 spoIIB S Sporulation related domain
NPPOIMGL_01717 1.6e-56 spoIIB S Sporulation related domain
NPPOIMGL_01718 2.8e-102 maf D septum formation protein Maf
NPPOIMGL_01719 5.9e-126 radC E Belongs to the UPF0758 family
NPPOIMGL_01720 1.8e-184 mreB D Rod shape-determining protein MreB
NPPOIMGL_01721 1.1e-156 mreC M Involved in formation and maintenance of cell shape
NPPOIMGL_01722 1.4e-84 mreD M shape-determining protein
NPPOIMGL_01723 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NPPOIMGL_01724 2.5e-144 minD D Belongs to the ParA family
NPPOIMGL_01725 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NPPOIMGL_01726 5.9e-160 spoIVFB S Stage IV sporulation protein
NPPOIMGL_01727 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NPPOIMGL_01728 4.1e-56 ysxB J ribosomal protein
NPPOIMGL_01729 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NPPOIMGL_01730 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NPPOIMGL_01731 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPPOIMGL_01732 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NPPOIMGL_01733 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
NPPOIMGL_01734 1.1e-85 niaR S small molecule binding protein (contains 3H domain)
NPPOIMGL_01735 3.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
NPPOIMGL_01736 4e-284 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NPPOIMGL_01737 1.3e-38 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NPPOIMGL_01738 2.8e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NPPOIMGL_01739 2e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NPPOIMGL_01740 8.3e-157 safA M spore coat assembly protein SafA
NPPOIMGL_01741 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPPOIMGL_01742 1.6e-126 yebC K transcriptional regulatory protein
NPPOIMGL_01743 4.5e-261 alsT E Sodium alanine symporter
NPPOIMGL_01744 1.1e-50 S Family of unknown function (DUF5412)
NPPOIMGL_01746 2.3e-35 yrzF T serine threonine protein kinase
NPPOIMGL_01747 4e-38 yrzF T serine threonine protein kinase
NPPOIMGL_01748 9.4e-57 yrzF T serine threonine protein kinase
NPPOIMGL_01749 2.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NPPOIMGL_01750 1.1e-195 csbX EGP Major facilitator Superfamily
NPPOIMGL_01751 4.8e-93 bofC S BofC C-terminal domain
NPPOIMGL_01752 7.7e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPPOIMGL_01753 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPPOIMGL_01754 6.9e-19 yrzS S Protein of unknown function (DUF2905)
NPPOIMGL_01755 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NPPOIMGL_01756 1.2e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NPPOIMGL_01757 1.1e-38 yajC U Preprotein translocase subunit YajC
NPPOIMGL_01758 1.5e-62 yrzE S Protein of unknown function (DUF3792)
NPPOIMGL_01760 1.1e-19 yrbG S membrane
NPPOIMGL_01761 6.5e-102 yrbG S membrane
NPPOIMGL_01763 2.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPPOIMGL_01764 1.6e-48 yrzD S Post-transcriptional regulator
NPPOIMGL_01765 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NPPOIMGL_01766 2.3e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NPPOIMGL_01767 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NPPOIMGL_01768 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NPPOIMGL_01769 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPPOIMGL_01770 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPPOIMGL_01771 6.4e-66 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPPOIMGL_01772 1.2e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
NPPOIMGL_01774 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NPPOIMGL_01775 1.2e-40 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NPPOIMGL_01776 3e-79 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NPPOIMGL_01777 7.1e-34 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NPPOIMGL_01778 6.6e-67 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NPPOIMGL_01779 3.6e-74 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NPPOIMGL_01780 9.8e-129 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NPPOIMGL_01781 4.5e-135 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NPPOIMGL_01782 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NPPOIMGL_01783 1.2e-70 cymR K Transcriptional regulator
NPPOIMGL_01784 9.8e-211 iscS 2.8.1.7 E Cysteine desulfurase
NPPOIMGL_01785 1.6e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPPOIMGL_01786 1.4e-15 S COG0457 FOG TPR repeat
NPPOIMGL_01787 5.1e-262 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPPOIMGL_01788 1.2e-205 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPPOIMGL_01789 2.7e-82 yrrD S protein conserved in bacteria
NPPOIMGL_01790 9.8e-31 yrzR
NPPOIMGL_01791 8e-08 S Protein of unknown function (DUF3918)
NPPOIMGL_01792 7.6e-107 glnP P ABC transporter
NPPOIMGL_01793 1.8e-108 gluC P ABC transporter
NPPOIMGL_01794 4.3e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
NPPOIMGL_01795 4.5e-125 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NPPOIMGL_01796 3.9e-169 yrrI S AI-2E family transporter
NPPOIMGL_01797 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPPOIMGL_01798 1.7e-41 yrzL S Belongs to the UPF0297 family
NPPOIMGL_01799 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPPOIMGL_01800 1.2e-45 yrzB S Belongs to the UPF0473 family
NPPOIMGL_01801 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NPPOIMGL_01802 5.2e-112 yrrM 2.1.1.104 S O-methyltransferase
NPPOIMGL_01803 8.6e-173 yegQ O Peptidase U32
NPPOIMGL_01804 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NPPOIMGL_01805 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NPPOIMGL_01806 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPPOIMGL_01807 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NPPOIMGL_01808 2.5e-60 yrrS S Protein of unknown function (DUF1510)
NPPOIMGL_01809 1e-25 yrzA S Protein of unknown function (DUF2536)
NPPOIMGL_01810 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NPPOIMGL_01811 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPPOIMGL_01812 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NPPOIMGL_01813 9.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NPPOIMGL_01814 4.6e-35 yrhC S YrhC-like protein
NPPOIMGL_01815 7.1e-78 yrhD S Protein of unknown function (DUF1641)
NPPOIMGL_01816 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NPPOIMGL_01817 1.7e-179 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NPPOIMGL_01818 2.5e-36 yrhF S Uncharacterized conserved protein (DUF2294)
NPPOIMGL_01819 8.1e-12 yrhF S Uncharacterized conserved protein (DUF2294)
NPPOIMGL_01820 8.1e-12 yrhF S Uncharacterized conserved protein (DUF2294)
NPPOIMGL_01821 3e-142 focA P Formate nitrite
NPPOIMGL_01824 1.5e-47 yrhH Q methyltransferase
NPPOIMGL_01825 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NPPOIMGL_01826 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NPPOIMGL_01827 9.1e-44 yrhK S YrhK-like protein
NPPOIMGL_01828 1.4e-72 yrhL I Acyltransferase family
NPPOIMGL_01829 2.7e-38 yrhL I Acyltransferase family
NPPOIMGL_01830 1.7e-238 yrhL I Acyltransferase family
NPPOIMGL_01831 2.5e-139 rsiV S Protein of unknown function (DUF3298)
NPPOIMGL_01832 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_01833 3.5e-149 yrhO K Archaeal transcriptional regulator TrmB
NPPOIMGL_01834 1.1e-105 yrhP E LysE type translocator
NPPOIMGL_01835 3e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NPPOIMGL_01836 0.0 levR K PTS system fructose IIA component
NPPOIMGL_01837 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
NPPOIMGL_01838 8.2e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NPPOIMGL_01839 2.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NPPOIMGL_01840 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NPPOIMGL_01841 1.1e-18 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NPPOIMGL_01842 3.8e-128 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NPPOIMGL_01843 2.6e-72 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NPPOIMGL_01844 1.7e-240 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NPPOIMGL_01845 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NPPOIMGL_01846 1.6e-157 adhA 1.1.1.1 C alcohol dehydrogenase
NPPOIMGL_01847 1.5e-83 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPPOIMGL_01849 1.1e-206 S aspartate phosphatase
NPPOIMGL_01850 2.7e-36 S Bacteriophage holin
NPPOIMGL_01852 7.1e-75 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NPPOIMGL_01854 2.4e-248 M Right handed beta helix region
NPPOIMGL_01855 1e-116
NPPOIMGL_01856 0.0 S Pfam Transposase IS66
NPPOIMGL_01857 6.2e-145 S Phage tail protein
NPPOIMGL_01858 0.0 S peptidoglycan catabolic process
NPPOIMGL_01859 5.4e-46
NPPOIMGL_01863 3.2e-189 xerH A Belongs to the 'phage' integrase family
NPPOIMGL_01864 8.1e-54
NPPOIMGL_01865 8.9e-41
NPPOIMGL_01866 5.8e-104 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
NPPOIMGL_01868 2.6e-19
NPPOIMGL_01869 1.2e-44 S Domain of unknown function (DUF2479)
NPPOIMGL_01870 2.4e-46
NPPOIMGL_01873 1.6e-87
NPPOIMGL_01874 1.5e-129
NPPOIMGL_01875 2.9e-90
NPPOIMGL_01876 3e-119
NPPOIMGL_01878 2.1e-64
NPPOIMGL_01879 1.1e-80
NPPOIMGL_01880 1.3e-185
NPPOIMGL_01881 2.3e-93
NPPOIMGL_01882 6e-250
NPPOIMGL_01883 9.4e-278
NPPOIMGL_01884 0.0 gp17a S Terminase-like family
NPPOIMGL_01885 7e-175
NPPOIMGL_01888 2.7e-227 S hydrolase activity
NPPOIMGL_01890 7.5e-32 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPPOIMGL_01891 4.2e-11
NPPOIMGL_01892 0.0
NPPOIMGL_01896 1.8e-47
NPPOIMGL_01898 1.7e-229 S DNA replication origin binding
NPPOIMGL_01901 1.9e-34 S DNA binding
NPPOIMGL_01902 2.4e-34
NPPOIMGL_01903 5.4e-32
NPPOIMGL_01908 2.5e-15 K Helix-turn-helix domain
NPPOIMGL_01910 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPPOIMGL_01911 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NPPOIMGL_01912 7.4e-148 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NPPOIMGL_01914 2e-15 xkdX
NPPOIMGL_01915 3e-56 S Bacteriophage holin family
NPPOIMGL_01918 3.5e-08 S YopX protein
NPPOIMGL_01924 3.5e-180 sppA OU signal peptide peptidase SppA
NPPOIMGL_01925 5e-87 yteJ S RDD family
NPPOIMGL_01926 8.1e-115 ytfI S Protein of unknown function (DUF2953)
NPPOIMGL_01927 8.7e-70 ytfJ S Sporulation protein YtfJ
NPPOIMGL_01928 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPPOIMGL_01929 6.6e-163 ytxK 2.1.1.72 L DNA methylase
NPPOIMGL_01930 4.1e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPPOIMGL_01931 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NPPOIMGL_01932 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NPPOIMGL_01933 7.5e-266 argH 4.3.2.1 E argininosuccinate lyase
NPPOIMGL_01935 7.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_01936 1.7e-130 ytkL S Belongs to the UPF0173 family
NPPOIMGL_01937 1.9e-172 ytlI K LysR substrate binding domain
NPPOIMGL_01938 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
NPPOIMGL_01939 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
NPPOIMGL_01940 1.9e-147 tcyK M Bacterial periplasmic substrate-binding proteins
NPPOIMGL_01941 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
NPPOIMGL_01942 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
NPPOIMGL_01943 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NPPOIMGL_01944 3.1e-184 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPPOIMGL_01945 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
NPPOIMGL_01946 7.5e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPPOIMGL_01947 2.6e-14 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NPPOIMGL_01948 4.5e-97 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NPPOIMGL_01949 2.3e-237 ytnL 3.5.1.47 E hydrolase activity
NPPOIMGL_01950 7.1e-156 ytnM S membrane transporter protein
NPPOIMGL_01951 8e-241 ytoI K transcriptional regulator containing CBS domains
NPPOIMGL_01952 2.4e-47 ytpI S YtpI-like protein
NPPOIMGL_01953 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NPPOIMGL_01954 9.2e-29
NPPOIMGL_01955 8.2e-69 ytrI
NPPOIMGL_01956 3.2e-56 ytrH S Sporulation protein YtrH
NPPOIMGL_01957 0.0 dnaE 2.7.7.7 L DNA polymerase
NPPOIMGL_01958 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NPPOIMGL_01959 2.4e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPPOIMGL_01960 8.3e-29 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NPPOIMGL_01961 3.3e-158 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NPPOIMGL_01962 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPPOIMGL_01963 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NPPOIMGL_01964 7e-35 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NPPOIMGL_01965 4.9e-47 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NPPOIMGL_01966 3.4e-192 ytvI S sporulation integral membrane protein YtvI
NPPOIMGL_01967 4.7e-71 yeaL S membrane
NPPOIMGL_01968 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NPPOIMGL_01969 4.1e-242 icd 1.1.1.42 C isocitrate
NPPOIMGL_01970 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NPPOIMGL_01971 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_01972 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NPPOIMGL_01973 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPPOIMGL_01974 5e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPPOIMGL_01975 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NPPOIMGL_01976 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPPOIMGL_01977 8e-96 ytbE S reductase
NPPOIMGL_01978 7.6e-20 ytbE S reductase
NPPOIMGL_01979 2.8e-55 ytbD EGP Major facilitator Superfamily
NPPOIMGL_01980 1.3e-144 ytbD EGP Major facilitator Superfamily
NPPOIMGL_01981 9.9e-67 ytcD K Transcriptional regulator
NPPOIMGL_01982 3.7e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPPOIMGL_01983 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NPPOIMGL_01984 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPPOIMGL_01985 9.8e-158 dnaB L Membrane attachment protein
NPPOIMGL_01986 3.8e-114 dnaB L Membrane attachment protein
NPPOIMGL_01987 6.6e-173 dnaI L Primosomal protein DnaI
NPPOIMGL_01988 6e-102 ytxB S SNARE associated Golgi protein
NPPOIMGL_01989 7.5e-43 ytxB S SNARE associated Golgi protein
NPPOIMGL_01990 4.2e-158 ytxC S YtxC-like family
NPPOIMGL_01992 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPPOIMGL_01993 7.3e-149 ysaA S HAD-hyrolase-like
NPPOIMGL_01994 2.6e-58 lytS 2.7.13.3 T Histidine kinase
NPPOIMGL_01995 4.5e-247 lytS 2.7.13.3 T Histidine kinase
NPPOIMGL_01996 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
NPPOIMGL_01997 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NPPOIMGL_01998 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NPPOIMGL_02000 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPPOIMGL_02001 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NPPOIMGL_02002 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPPOIMGL_02003 7.5e-45 ysdA S Membrane
NPPOIMGL_02004 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NPPOIMGL_02005 3e-123 ysdC G COG1363 Cellulase M and related proteins
NPPOIMGL_02006 7.8e-42 ysdC G COG1363 Cellulase M and related proteins
NPPOIMGL_02007 6.2e-55 ysdC G COG1363 Cellulase M and related proteins
NPPOIMGL_02008 3.3e-22 ysdC G COG1363 Cellulase M and related proteins
NPPOIMGL_02009 3.6e-41 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NPPOIMGL_02010 1.1e-102 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NPPOIMGL_02011 5.3e-28 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NPPOIMGL_02012 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NPPOIMGL_02013 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NPPOIMGL_02014 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NPPOIMGL_02015 6.2e-127 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NPPOIMGL_02016 4.2e-14 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NPPOIMGL_02017 7.2e-103 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NPPOIMGL_02018 5.9e-103 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NPPOIMGL_02019 2.5e-80 araN G carbohydrate transport
NPPOIMGL_02020 2.5e-134 araN G carbohydrate transport
NPPOIMGL_02021 2.1e-54 araN G carbohydrate transport
NPPOIMGL_02022 1.4e-167 araP G carbohydrate transport
NPPOIMGL_02023 2.9e-143 araQ G transport system permease
NPPOIMGL_02024 1.7e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NPPOIMGL_02025 0.0 cstA T Carbon starvation protein
NPPOIMGL_02026 2.3e-52 ysfE 4.4.1.5 E Glyoxalase-like domain
NPPOIMGL_02027 3.8e-240 glcF C Glycolate oxidase
NPPOIMGL_02028 7e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
NPPOIMGL_02029 2.1e-202 ysfB KT regulator
NPPOIMGL_02030 5.8e-32 sspI S Belongs to the SspI family
NPPOIMGL_02031 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPPOIMGL_02032 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPPOIMGL_02033 1.4e-281 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPPOIMGL_02034 6.2e-140 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPPOIMGL_02035 4.1e-64 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPPOIMGL_02036 5.2e-38 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPPOIMGL_02037 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NPPOIMGL_02038 1.7e-85 cvpA S membrane protein, required for colicin V production
NPPOIMGL_02039 0.0 polX L COG1796 DNA polymerase IV (family X)
NPPOIMGL_02040 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPPOIMGL_02041 7.3e-68 yshE S membrane
NPPOIMGL_02042 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NPPOIMGL_02043 1.4e-99 fadR K Transcriptional regulator
NPPOIMGL_02044 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NPPOIMGL_02045 1.1e-133 etfB C Electron transfer flavoprotein
NPPOIMGL_02046 1.8e-169 etfA C Electron transfer flavoprotein
NPPOIMGL_02048 2.5e-299 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NPPOIMGL_02049 2e-52 trxA O Belongs to the thioredoxin family
NPPOIMGL_02050 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPPOIMGL_02051 2e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NPPOIMGL_02052 1.2e-79 yslB S Protein of unknown function (DUF2507)
NPPOIMGL_02053 2.4e-107 sdhC C succinate dehydrogenase
NPPOIMGL_02054 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NPPOIMGL_02055 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NPPOIMGL_02056 3.2e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NPPOIMGL_02057 1.2e-17 gerE K Transcriptional regulator
NPPOIMGL_02058 1.2e-48 yqaB E IrrE N-terminal-like domain
NPPOIMGL_02059 8.5e-20
NPPOIMGL_02061 4.4e-16 K sequence-specific DNA binding
NPPOIMGL_02062 3.2e-13 K Helix-turn-helix XRE-family like proteins
NPPOIMGL_02064 4.3e-92 recT L Recombinational DNA repair protein (RecE pathway)
NPPOIMGL_02065 1.1e-109 S YqaJ-like viral recombinase domain
NPPOIMGL_02068 1.7e-12 K Helix-turn-helix XRE-family like proteins
NPPOIMGL_02069 2e-49 MA20_18690 S Protein of unknown function (DUF3237)
NPPOIMGL_02070 1.7e-92 padC Q Phenolic acid decarboxylase
NPPOIMGL_02072 3.5e-76 spo0M S COG4326 Sporulation control protein
NPPOIMGL_02073 1.7e-54 yrdC 3.5.1.19 Q Isochorismatase family
NPPOIMGL_02077 7e-56
NPPOIMGL_02078 2.4e-47 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
NPPOIMGL_02079 2.7e-50 2.7.7.73, 2.7.7.80 H ThiF family
NPPOIMGL_02080 4.6e-45
NPPOIMGL_02081 2e-63 S Major Facilitator Superfamily
NPPOIMGL_02082 8.8e-57 1.14.11.27 S JmjC domain, hydroxylase
NPPOIMGL_02083 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_02084 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_02085 1.3e-163 feuA P Iron-uptake system-binding protein
NPPOIMGL_02086 3.8e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NPPOIMGL_02087 3.2e-234 ybbC 3.2.1.52 S protein conserved in bacteria
NPPOIMGL_02088 1.5e-104 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NPPOIMGL_02089 1.2e-250 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NPPOIMGL_02090 3.5e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NPPOIMGL_02091 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPPOIMGL_02092 1.4e-150 ybbH K transcriptional
NPPOIMGL_02093 8.8e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NPPOIMGL_02094 6e-83 ybbJ J acetyltransferase
NPPOIMGL_02095 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NPPOIMGL_02100 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_02101 1.2e-101 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NPPOIMGL_02102 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPPOIMGL_02103 3e-225 ybbR S protein conserved in bacteria
NPPOIMGL_02104 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPPOIMGL_02105 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPPOIMGL_02106 7.1e-46 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPPOIMGL_02107 6.7e-59 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPPOIMGL_02108 2.1e-80 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPPOIMGL_02109 1.2e-42 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPPOIMGL_02110 2.8e-25 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPPOIMGL_02111 9.8e-120 adaA 3.2.2.21 K Transcriptional regulator
NPPOIMGL_02112 5.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPPOIMGL_02113 2e-262 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NPPOIMGL_02114 0.0 ybcC S Belongs to the UPF0753 family
NPPOIMGL_02115 3.7e-187 ybcC S Belongs to the UPF0753 family
NPPOIMGL_02116 2.9e-71 can 4.2.1.1 P carbonic anhydrase
NPPOIMGL_02117 1.9e-46
NPPOIMGL_02118 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NPPOIMGL_02119 5.1e-50 ybzH K Helix-turn-helix domain
NPPOIMGL_02120 7.8e-119 ybcL EGP Major facilitator Superfamily
NPPOIMGL_02121 6.5e-79 ybcL EGP Major facilitator Superfamily
NPPOIMGL_02123 2e-238 J 4Fe-4S single cluster domain
NPPOIMGL_02124 2.5e-275 V CAAX protease self-immunity
NPPOIMGL_02125 6.7e-133 skfE V ABC transporter
NPPOIMGL_02126 1.5e-245 skfF S ABC transporter
NPPOIMGL_02127 7.8e-91 C HEAT repeats
NPPOIMGL_02128 9.6e-79 txn CO Thioredoxin-like
NPPOIMGL_02129 2.9e-179 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NPPOIMGL_02130 1e-114 T Transcriptional regulatory protein, C terminal
NPPOIMGL_02131 1.9e-34 T His Kinase A (phospho-acceptor) domain
NPPOIMGL_02132 1.1e-74 T His Kinase A (phospho-acceptor) domain
NPPOIMGL_02133 8.9e-43 T His Kinase A (phospho-acceptor) domain
NPPOIMGL_02135 6.1e-140 KLT Protein tyrosine kinase
NPPOIMGL_02136 1.8e-85 ybdN
NPPOIMGL_02137 2.9e-11 ybdN
NPPOIMGL_02138 1.3e-116 ybdO S Domain of unknown function (DUF4885)
NPPOIMGL_02139 2e-23 ybdO S Domain of unknown function (DUF4885)
NPPOIMGL_02140 1.9e-107 ybdO S Domain of unknown function (DUF4885)
NPPOIMGL_02141 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NPPOIMGL_02142 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
NPPOIMGL_02143 4.9e-30 ybxH S Family of unknown function (DUF5370)
NPPOIMGL_02144 4.8e-45 ybxI 3.5.2.6 V beta-lactamase
NPPOIMGL_02145 7.2e-94 ybxI 3.5.2.6 V beta-lactamase
NPPOIMGL_02146 1.7e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NPPOIMGL_02147 1.2e-20 ybyB
NPPOIMGL_02148 1.3e-31 ybyB
NPPOIMGL_02149 1.8e-20 ybyB
NPPOIMGL_02150 1.8e-228 ybeC E amino acid
NPPOIMGL_02151 6.1e-35 ybeC E amino acid
NPPOIMGL_02152 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPPOIMGL_02153 7.3e-258 glpT G -transporter
NPPOIMGL_02154 1.5e-34 S Protein of unknown function (DUF2651)
NPPOIMGL_02155 6.3e-168 ybfA 3.4.15.5 K FR47-like protein
NPPOIMGL_02156 6.6e-208 ybfB G COG0477 Permeases of the major facilitator superfamily
NPPOIMGL_02159 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NPPOIMGL_02160 4.1e-102 ybfH EG EamA-like transporter family
NPPOIMGL_02161 2.9e-83 ybfH EG EamA-like transporter family
NPPOIMGL_02162 1.1e-18 ybfH EG EamA-like transporter family
NPPOIMGL_02163 3.1e-64 msmR K AraC-like ligand binding domain
NPPOIMGL_02164 3.2e-77 msmR K AraC-like ligand binding domain
NPPOIMGL_02165 7.9e-152 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NPPOIMGL_02166 4.8e-70 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NPPOIMGL_02167 2.2e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NPPOIMGL_02169 2.6e-166 S Alpha/beta hydrolase family
NPPOIMGL_02170 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPPOIMGL_02171 2.7e-85 ybfM S SNARE associated Golgi protein
NPPOIMGL_02172 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NPPOIMGL_02173 1.2e-45 ybfN
NPPOIMGL_02174 2.4e-253 S Erythromycin esterase
NPPOIMGL_02175 3.9e-207 S Erythromycin esterase
NPPOIMGL_02176 2.1e-15 S Erythromycin esterase
NPPOIMGL_02177 6.7e-167 ybfP K Transcriptional regulator
NPPOIMGL_02178 3.4e-154 yceA S Belongs to the UPF0176 family
NPPOIMGL_02179 8.4e-59 yceA S Belongs to the UPF0176 family
NPPOIMGL_02180 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPPOIMGL_02181 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPPOIMGL_02182 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPPOIMGL_02183 3.2e-127 K UTRA
NPPOIMGL_02185 5.5e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NPPOIMGL_02186 3.1e-259 mmuP E amino acid
NPPOIMGL_02187 7.4e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NPPOIMGL_02189 2.1e-28 agcS E Sodium alanine symporter
NPPOIMGL_02190 4e-224 agcS E Sodium alanine symporter
NPPOIMGL_02191 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
NPPOIMGL_02192 1.1e-206 phoQ 2.7.13.3 T Histidine kinase
NPPOIMGL_02193 9e-170 glnL T Regulator
NPPOIMGL_02194 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NPPOIMGL_02195 3.4e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPPOIMGL_02196 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NPPOIMGL_02197 7.2e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NPPOIMGL_02198 2.1e-123 ycbG K FCD
NPPOIMGL_02199 9.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
NPPOIMGL_02200 3.8e-131 ycbJ S Macrolide 2'-phosphotransferase
NPPOIMGL_02201 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NPPOIMGL_02202 8.3e-168 eamA1 EG spore germination
NPPOIMGL_02203 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_02204 1.6e-166 T PhoQ Sensor
NPPOIMGL_02205 3.9e-158 ycbN V ABC transporter, ATP-binding protein
NPPOIMGL_02206 7.4e-113 S ABC-2 family transporter protein
NPPOIMGL_02207 4.1e-52 ycbP S Protein of unknown function (DUF2512)
NPPOIMGL_02208 7.7e-14 sleB 3.5.1.28 M Cell wall
NPPOIMGL_02209 3.3e-65 sleB 3.5.1.28 M Cell wall
NPPOIMGL_02210 4.7e-134 ycbR T vWA found in TerF C terminus
NPPOIMGL_02211 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NPPOIMGL_02212 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NPPOIMGL_02213 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NPPOIMGL_02214 2.5e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NPPOIMGL_02215 1.1e-203 ycbU E Selenocysteine lyase
NPPOIMGL_02216 6.9e-214 lmrB EGP the major facilitator superfamily
NPPOIMGL_02217 5.9e-100 yxaF K Transcriptional regulator
NPPOIMGL_02218 7.6e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NPPOIMGL_02219 9.3e-102 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NPPOIMGL_02220 4.5e-59 S RDD family
NPPOIMGL_02221 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
NPPOIMGL_02222 9.5e-151 2.7.13.3 T GHKL domain
NPPOIMGL_02223 1.2e-126 lytR_2 T LytTr DNA-binding domain
NPPOIMGL_02224 1.2e-50 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NPPOIMGL_02225 7.2e-80 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NPPOIMGL_02226 3.5e-200 natB CP ABC-2 family transporter protein
NPPOIMGL_02227 1.4e-168 yccK C Aldo keto reductase
NPPOIMGL_02228 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NPPOIMGL_02229 2.9e-07 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_02230 1.3e-262 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_02231 3.9e-260 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_02232 1.2e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
NPPOIMGL_02233 1.1e-164 S response regulator aspartate phosphatase
NPPOIMGL_02234 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
NPPOIMGL_02235 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NPPOIMGL_02236 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
NPPOIMGL_02237 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NPPOIMGL_02238 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NPPOIMGL_02239 1.9e-31 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPPOIMGL_02240 3.8e-154 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPPOIMGL_02241 1e-60 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NPPOIMGL_02242 2.4e-46 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NPPOIMGL_02243 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NPPOIMGL_02244 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NPPOIMGL_02245 6.3e-137 terC P Protein of unknown function (DUF475)
NPPOIMGL_02246 0.0 yceG S Putative component of 'biosynthetic module'
NPPOIMGL_02247 2e-192 yceH P Belongs to the TelA family
NPPOIMGL_02248 4.8e-200 naiP P Uncharacterised MFS-type transporter YbfB
NPPOIMGL_02249 2e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
NPPOIMGL_02250 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NPPOIMGL_02251 1.3e-227 proV 3.6.3.32 E glycine betaine
NPPOIMGL_02252 3.9e-26 proV 3.6.3.32 E glycine betaine
NPPOIMGL_02253 1.7e-12 opuAB P glycine betaine
NPPOIMGL_02254 8.5e-127 opuAB P glycine betaine
NPPOIMGL_02255 5.3e-164 opuAC E glycine betaine
NPPOIMGL_02256 4.1e-217 amhX S amidohydrolase
NPPOIMGL_02257 8.7e-257 ycgA S Membrane
NPPOIMGL_02258 2.4e-63 ycgB
NPPOIMGL_02259 5.5e-275 amyE 3.2.1.1 GH13 G alpha-amylase
NPPOIMGL_02260 2e-106 amyE 3.2.1.1 GH13 G alpha-amylase
NPPOIMGL_02261 1.3e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPPOIMGL_02262 9.2e-285 lctP C L-lactate permease
NPPOIMGL_02263 6.1e-18 lctP C L-lactate permease
NPPOIMGL_02264 3.9e-263 mdr EGP Major facilitator Superfamily
NPPOIMGL_02265 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
NPPOIMGL_02266 3.5e-38 ycgF E Lysine exporter protein LysE YggA
NPPOIMGL_02267 7.3e-29 ycgF E Lysine exporter protein LysE YggA
NPPOIMGL_02268 2.9e-150 yqcI S YqcI/YcgG family
NPPOIMGL_02269 2.1e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NPPOIMGL_02271 4.3e-94 ycgI S Domain of unknown function (DUF1989)
NPPOIMGL_02272 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPPOIMGL_02273 2.4e-69 tmrB S AAA domain
NPPOIMGL_02275 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NPPOIMGL_02276 2.4e-144 yafE Q ubiE/COQ5 methyltransferase family
NPPOIMGL_02277 7.9e-177 oxyR3 K LysR substrate binding domain
NPPOIMGL_02278 2.1e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NPPOIMGL_02279 2.4e-144 ycgL S Predicted nucleotidyltransferase
NPPOIMGL_02280 2.5e-169 ycgM E Proline dehydrogenase
NPPOIMGL_02281 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NPPOIMGL_02282 2e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPPOIMGL_02283 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NPPOIMGL_02284 2.6e-147 ycgQ S membrane
NPPOIMGL_02285 3.5e-139 ycgR S permeases
NPPOIMGL_02286 1e-159 I alpha/beta hydrolase fold
NPPOIMGL_02287 3.6e-126 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NPPOIMGL_02288 4.8e-57 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NPPOIMGL_02289 2.4e-147 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NPPOIMGL_02290 2.2e-121 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NPPOIMGL_02291 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NPPOIMGL_02292 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NPPOIMGL_02293 4.8e-140 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NPPOIMGL_02294 1.2e-103 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPPOIMGL_02295 3.2e-300 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPPOIMGL_02296 1.3e-199 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NPPOIMGL_02297 1.1e-239 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NPPOIMGL_02298 1.1e-210 nasA P COG2223 Nitrate nitrite transporter
NPPOIMGL_02299 7e-38 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NPPOIMGL_02300 2.3e-82 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NPPOIMGL_02301 5.7e-43 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NPPOIMGL_02302 1.7e-38 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NPPOIMGL_02303 1.8e-107 yciB M ErfK YbiS YcfS YnhG
NPPOIMGL_02304 8.6e-226 yciC S GTPases (G3E family)
NPPOIMGL_02305 3.2e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NPPOIMGL_02306 1.7e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NPPOIMGL_02308 1.2e-67 yckC S membrane
NPPOIMGL_02309 9.2e-11 yckD S Protein of unknown function (DUF2680)
NPPOIMGL_02310 8.8e-48 yckD S Protein of unknown function (DUF2680)
NPPOIMGL_02311 3.1e-45 K MarR family
NPPOIMGL_02312 9.3e-24
NPPOIMGL_02314 1.3e-97 S AAA domain
NPPOIMGL_02315 4e-294 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPPOIMGL_02316 1.1e-68 nin S Competence protein J (ComJ)
NPPOIMGL_02317 4.1e-39 nucA M Deoxyribonuclease NucA/NucB
NPPOIMGL_02318 4.1e-179 tlpC 2.7.13.3 NT chemotaxis protein
NPPOIMGL_02319 5.6e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NPPOIMGL_02320 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NPPOIMGL_02321 1.3e-63 hxlR K transcriptional
NPPOIMGL_02322 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_02323 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_02324 2.7e-85 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_02325 2.3e-24 3.1.3.16 L DnaD domain protein
NPPOIMGL_02326 1.2e-19 S Phage Mu protein F like protein
NPPOIMGL_02327 1.5e-18 S Phage gp6-like head-tail connector protein
NPPOIMGL_02328 2.7e-61 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPPOIMGL_02329 9.3e-16
NPPOIMGL_02334 7.1e-198 yxjM T Histidine kinase
NPPOIMGL_02335 2e-85 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPPOIMGL_02336 6.8e-34 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPPOIMGL_02337 4.3e-67 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPPOIMGL_02338 4.8e-85 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPPOIMGL_02339 1.5e-197 oppD P Belongs to the ABC transporter superfamily
NPPOIMGL_02340 4.5e-163 oppF E Belongs to the ABC transporter superfamily
NPPOIMGL_02341 7.1e-33 oppF E Belongs to the ABC transporter superfamily
NPPOIMGL_02342 4.5e-203 yjbB EGP Major Facilitator Superfamily
NPPOIMGL_02343 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPPOIMGL_02344 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPPOIMGL_02345 6e-112 yjbE P Integral membrane protein TerC family
NPPOIMGL_02346 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NPPOIMGL_02347 4.4e-219 yjbF S Competence protein
NPPOIMGL_02348 0.0 pepF E oligoendopeptidase F
NPPOIMGL_02349 1.8e-20
NPPOIMGL_02351 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NPPOIMGL_02352 3.7e-72 yjbI S Bacterial-like globin
NPPOIMGL_02353 9.8e-79 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NPPOIMGL_02354 4.1e-101 yjbK S protein conserved in bacteria
NPPOIMGL_02355 2.7e-61 yjbL S Belongs to the UPF0738 family
NPPOIMGL_02356 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NPPOIMGL_02357 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPPOIMGL_02358 5.7e-150 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPPOIMGL_02359 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NPPOIMGL_02360 6.4e-14 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPPOIMGL_02361 2.1e-65 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPPOIMGL_02362 5.3e-254 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPPOIMGL_02363 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NPPOIMGL_02364 7.3e-97 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NPPOIMGL_02365 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
NPPOIMGL_02366 6.7e-30 thiS H thiamine diphosphate biosynthetic process
NPPOIMGL_02367 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NPPOIMGL_02368 8.1e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NPPOIMGL_02369 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NPPOIMGL_02370 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NPPOIMGL_02371 1.7e-47 yjbX S Spore coat protein
NPPOIMGL_02372 5.2e-83 cotZ S Spore coat protein
NPPOIMGL_02373 3.4e-96 cotY S Spore coat protein Z
NPPOIMGL_02374 6.4e-77 cotX S Spore Coat Protein X and V domain
NPPOIMGL_02375 8.5e-32 cotW
NPPOIMGL_02376 2.3e-55 cotV S Spore Coat Protein X and V domain
NPPOIMGL_02377 4.3e-56 yjcA S Protein of unknown function (DUF1360)
NPPOIMGL_02380 2.9e-38 spoVIF S Stage VI sporulation protein F
NPPOIMGL_02381 0.0 yjcD 3.6.4.12 L DNA helicase
NPPOIMGL_02382 1.7e-38
NPPOIMGL_02383 1.1e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPPOIMGL_02384 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NPPOIMGL_02385 7.6e-45 yjcH P COG2382 Enterochelin esterase and related enzymes
NPPOIMGL_02386 4.7e-91 yjcH P COG2382 Enterochelin esterase and related enzymes
NPPOIMGL_02387 1.2e-213 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NPPOIMGL_02388 2.3e-135 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NPPOIMGL_02389 1.9e-40 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NPPOIMGL_02390 5.9e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
NPPOIMGL_02391 4.7e-95 yjcL S Protein of unknown function (DUF819)
NPPOIMGL_02392 1.2e-101 yjcL S Protein of unknown function (DUF819)
NPPOIMGL_02394 9.7e-21 recT L Recombinational DNA repair protein (RecE pathway)
NPPOIMGL_02397 1.3e-07
NPPOIMGL_02399 1.2e-90 tcaA S response to antibiotic
NPPOIMGL_02400 5.4e-75 yvbK 3.1.3.25 K acetyltransferase
NPPOIMGL_02401 1.9e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPPOIMGL_02402 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NPPOIMGL_02403 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPPOIMGL_02404 1.5e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NPPOIMGL_02405 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPPOIMGL_02406 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NPPOIMGL_02407 1.6e-252 araE EGP Major facilitator Superfamily
NPPOIMGL_02408 5.5e-203 araR K transcriptional
NPPOIMGL_02409 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPPOIMGL_02410 6.7e-159 yvbU K Transcriptional regulator
NPPOIMGL_02411 9.4e-156 yvbV EG EamA-like transporter family
NPPOIMGL_02412 6.3e-88 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NPPOIMGL_02413 3.7e-136 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NPPOIMGL_02414 9.8e-194 yvbX S Glycosyl hydrolase
NPPOIMGL_02415 6.7e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NPPOIMGL_02416 9.7e-206 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NPPOIMGL_02417 9.1e-47 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NPPOIMGL_02418 7.5e-45 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NPPOIMGL_02419 2.8e-102 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NPPOIMGL_02420 5e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPPOIMGL_02421 2.1e-197 desK 2.7.13.3 T Histidine kinase
NPPOIMGL_02422 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
NPPOIMGL_02423 2.9e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NPPOIMGL_02424 2.2e-156 rsbQ S Alpha/beta hydrolase family
NPPOIMGL_02425 2.3e-102 rsbU 3.1.3.3 T response regulator
NPPOIMGL_02426 4.2e-77 rsbU 3.1.3.3 T response regulator
NPPOIMGL_02427 8.2e-215 galA 3.2.1.89 G arabinogalactan
NPPOIMGL_02428 5.7e-190 lacA 3.2.1.23 G beta-galactosidase
NPPOIMGL_02429 7.6e-230 lacA 3.2.1.23 G beta-galactosidase
NPPOIMGL_02430 7.2e-150 ganQ P transport
NPPOIMGL_02431 1e-96 malC P COG1175 ABC-type sugar transport systems, permease components
NPPOIMGL_02432 2.8e-140 malC P COG1175 ABC-type sugar transport systems, permease components
NPPOIMGL_02433 7.6e-223 cycB G COG2182 Maltose-binding periplasmic proteins domains
NPPOIMGL_02434 1.8e-184 lacR K Transcriptional regulator
NPPOIMGL_02435 1e-112 yvfI K COG2186 Transcriptional regulators
NPPOIMGL_02436 3.3e-308 yvfH C L-lactate permease
NPPOIMGL_02437 3.3e-210 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NPPOIMGL_02438 1e-31 yvfG S YvfG protein
NPPOIMGL_02439 2.3e-148 yvfF GM Exopolysaccharide biosynthesis protein
NPPOIMGL_02440 7e-71 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NPPOIMGL_02441 2.2e-117 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NPPOIMGL_02442 6.4e-50 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NPPOIMGL_02443 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NPPOIMGL_02444 7.8e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPPOIMGL_02445 4.7e-186 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NPPOIMGL_02446 8.6e-40 epsI GM pyruvyl transferase
NPPOIMGL_02447 2.6e-132 epsI GM pyruvyl transferase
NPPOIMGL_02448 4.9e-193 epsH GT2 S Glycosyltransferase like family 2
NPPOIMGL_02449 1.1e-206 epsG S EpsG family
NPPOIMGL_02450 1.6e-52 epsF GT4 M Glycosyl transferases group 1
NPPOIMGL_02451 1e-148 epsF GT4 M Glycosyl transferases group 1
NPPOIMGL_02452 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NPPOIMGL_02453 8e-221 epsD GT4 M Glycosyl transferase 4-like
NPPOIMGL_02454 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NPPOIMGL_02455 3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NPPOIMGL_02456 8.6e-66 ywqC M biosynthesis protein
NPPOIMGL_02457 1.5e-48 ywqC M biosynthesis protein
NPPOIMGL_02458 6.3e-76 slr K transcriptional
NPPOIMGL_02459 5.2e-23
NPPOIMGL_02461 1.8e-81 ydcR 2.7.7.65 T Diguanylate cyclase
NPPOIMGL_02462 7.4e-80 ydcR 2.7.7.65 T Diguanylate cyclase
NPPOIMGL_02463 1.5e-135 L COG2801 Transposase and inactivated derivatives
NPPOIMGL_02466 1.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NPPOIMGL_02467 1.3e-81 mhqR K transcriptional
NPPOIMGL_02468 6.9e-26 ykoL
NPPOIMGL_02469 5.9e-18
NPPOIMGL_02470 1.4e-53 tnrA K transcriptional
NPPOIMGL_02471 2.2e-222 mgtE P Acts as a magnesium transporter
NPPOIMGL_02474 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
NPPOIMGL_02475 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
NPPOIMGL_02476 1.8e-142 ykoH 2.7.13.3 T Histidine kinase
NPPOIMGL_02477 2.5e-88 ykoH 2.7.13.3 T Histidine kinase
NPPOIMGL_02478 4.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_02479 5.1e-110 ykoF S YKOF-related Family
NPPOIMGL_02480 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
NPPOIMGL_02481 1.2e-305 P ABC transporter, ATP-binding protein
NPPOIMGL_02482 9.6e-17 ykoC P Cobalt transport protein
NPPOIMGL_02483 7.6e-135 ykoC P Cobalt transport protein
NPPOIMGL_02484 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPPOIMGL_02485 1.5e-175 isp O Belongs to the peptidase S8 family
NPPOIMGL_02486 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NPPOIMGL_02487 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NPPOIMGL_02488 8.4e-72 ohrB O Organic hydroperoxide resistance protein
NPPOIMGL_02489 1.2e-68 ohrR K COG1846 Transcriptional regulators
NPPOIMGL_02490 7.7e-18 ohrR K COG1846 Transcriptional regulators
NPPOIMGL_02491 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NPPOIMGL_02492 4.5e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NPPOIMGL_02493 1.8e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPPOIMGL_02494 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NPPOIMGL_02495 9.1e-50 ykkD P Multidrug resistance protein
NPPOIMGL_02496 1.7e-54 ykkC P Multidrug resistance protein
NPPOIMGL_02497 9.9e-94 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPPOIMGL_02498 5.7e-97 ykkA S Protein of unknown function (DUF664)
NPPOIMGL_02499 3.7e-119 ykjA S Protein of unknown function (DUF421)
NPPOIMGL_02501 2.8e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NPPOIMGL_02502 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NPPOIMGL_02503 5.4e-154 ykgA E Amidinotransferase
NPPOIMGL_02504 2.6e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
NPPOIMGL_02505 1.2e-84 ykfD E Belongs to the ABC transporter superfamily
NPPOIMGL_02506 9.3e-63 ykfD E Belongs to the ABC transporter superfamily
NPPOIMGL_02507 1.4e-31 ykfD E Belongs to the ABC transporter superfamily
NPPOIMGL_02508 1.3e-69 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPPOIMGL_02509 2.6e-47 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPPOIMGL_02510 2.3e-37 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPPOIMGL_02511 1.2e-56 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPPOIMGL_02512 3e-59 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPPOIMGL_02513 4.7e-189 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NPPOIMGL_02514 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NPPOIMGL_02516 0.0 dppE E ABC transporter substrate-binding protein
NPPOIMGL_02517 1.4e-182 dppD P Belongs to the ABC transporter superfamily
NPPOIMGL_02518 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPPOIMGL_02519 4.5e-155 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPPOIMGL_02520 5.1e-153 dppA E D-aminopeptidase
NPPOIMGL_02521 2.1e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NPPOIMGL_02522 8.9e-211 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPPOIMGL_02524 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NPPOIMGL_02525 5.4e-117 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPPOIMGL_02526 1.5e-80 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPPOIMGL_02527 4.8e-38 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPPOIMGL_02528 1.4e-105 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPPOIMGL_02530 3e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NPPOIMGL_02531 5.8e-147 steT E amino acid
NPPOIMGL_02532 1.1e-84 steT E amino acid
NPPOIMGL_02533 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NPPOIMGL_02534 6.9e-137 pit P phosphate transporter
NPPOIMGL_02535 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NPPOIMGL_02536 6.7e-23 spoIISB S Stage II sporulation protein SB
NPPOIMGL_02537 7.7e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPPOIMGL_02538 9.3e-40 xhlB S SPP1 phage holin
NPPOIMGL_02539 2.7e-36 xhlA S Haemolysin XhlA
NPPOIMGL_02540 3.6e-141 xepA
NPPOIMGL_02541 5.5e-22 xkdX
NPPOIMGL_02542 9.4e-18 xkdW S XkdW protein
NPPOIMGL_02543 6.3e-157
NPPOIMGL_02544 1.8e-36 padR K Transcriptional regulator PadR-like family
NPPOIMGL_02546 8.9e-38 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPPOIMGL_02547 2.4e-71 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPPOIMGL_02548 2.9e-31 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_02551 2.2e-63 rocB E arginine degradation protein
NPPOIMGL_02552 7.3e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPPOIMGL_02553 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NPPOIMGL_02554 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_02556 4.3e-65 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NPPOIMGL_02557 1e-182 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NPPOIMGL_02558 1.7e-26 coaA 2.7.1.33 F Pantothenic acid kinase
NPPOIMGL_02559 1.1e-155 coaA 2.7.1.33 F Pantothenic acid kinase
NPPOIMGL_02560 3.2e-26 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPPOIMGL_02561 7.1e-30 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPPOIMGL_02562 2.6e-33 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPPOIMGL_02564 5.9e-203 yqjV G Major Facilitator Superfamily
NPPOIMGL_02566 3.5e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPPOIMGL_02567 1.7e-49 S YolD-like protein
NPPOIMGL_02568 1.1e-86 yqjY K acetyltransferase
NPPOIMGL_02569 4.4e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NPPOIMGL_02570 1.1e-192 yqkA K GrpB protein
NPPOIMGL_02571 2.8e-54 yqkB S Belongs to the HesB IscA family
NPPOIMGL_02572 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NPPOIMGL_02573 9.4e-149 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NPPOIMGL_02574 1.8e-26 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NPPOIMGL_02575 3.1e-12 yqkE S Protein of unknown function (DUF3886)
NPPOIMGL_02576 1.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NPPOIMGL_02578 5.8e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NPPOIMGL_02579 1.4e-220 yqxK 3.6.4.12 L DNA helicase
NPPOIMGL_02580 4.5e-58 ansR K Transcriptional regulator
NPPOIMGL_02581 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase
NPPOIMGL_02582 1.4e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NPPOIMGL_02583 1.4e-133 mleN C Na H antiporter
NPPOIMGL_02584 8.6e-128 mleN C Na H antiporter
NPPOIMGL_02585 1.2e-239 mleA 1.1.1.38 C malic enzyme
NPPOIMGL_02586 3.2e-30 yqkK
NPPOIMGL_02587 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NPPOIMGL_02588 2.4e-80 fur P Belongs to the Fur family
NPPOIMGL_02589 3.7e-37 S Protein of unknown function (DUF4227)
NPPOIMGL_02590 7.6e-29 xerD L recombinase XerD
NPPOIMGL_02591 3.8e-122 xerD L recombinase XerD
NPPOIMGL_02592 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NPPOIMGL_02593 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NPPOIMGL_02594 1.1e-148 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NPPOIMGL_02595 1.2e-58 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NPPOIMGL_02596 1.5e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NPPOIMGL_02597 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NPPOIMGL_02598 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPPOIMGL_02599 9.6e-112 spoVAA S Stage V sporulation protein AA
NPPOIMGL_02600 1e-67 spoVAB S Stage V sporulation protein AB
NPPOIMGL_02601 2.3e-78 spoVAC S stage V sporulation protein AC
NPPOIMGL_02602 9e-192 spoVAD I Stage V sporulation protein AD
NPPOIMGL_02603 2.2e-57 spoVAEB S stage V sporulation protein
NPPOIMGL_02604 1.4e-110 spoVAEA S stage V sporulation protein
NPPOIMGL_02605 3.4e-267 spoVAF EG Stage V sporulation protein AF
NPPOIMGL_02606 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPPOIMGL_02607 1.5e-71 ypuA S Secreted protein
NPPOIMGL_02608 6.9e-37 ypuA S Secreted protein
NPPOIMGL_02609 1.7e-35 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPPOIMGL_02613 7.3e-07
NPPOIMGL_02615 5.6e-21 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NPPOIMGL_02616 1.7e-132 tagG GM Transport permease protein
NPPOIMGL_02617 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPPOIMGL_02618 5.3e-240 ggaA M Glycosyltransferase like family 2
NPPOIMGL_02619 1.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NPPOIMGL_02620 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NPPOIMGL_02621 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPPOIMGL_02622 1.1e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NPPOIMGL_02623 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NPPOIMGL_02624 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NPPOIMGL_02625 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPPOIMGL_02626 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPPOIMGL_02627 2.3e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPPOIMGL_02628 1.7e-93 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NPPOIMGL_02629 9.7e-39 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NPPOIMGL_02630 7.3e-112 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NPPOIMGL_02631 5.7e-264 gerBA EG Spore germination protein
NPPOIMGL_02632 4.3e-56 gerBB E Spore germination protein
NPPOIMGL_02633 1.2e-121 gerBB E Spore germination protein
NPPOIMGL_02634 7.9e-115 gerAC S Spore germination protein
NPPOIMGL_02635 2.5e-68 gerAC S Spore germination protein
NPPOIMGL_02636 1e-168 ywtG EGP Major facilitator Superfamily
NPPOIMGL_02637 6.3e-45 ywtG EGP Major facilitator Superfamily
NPPOIMGL_02638 2.1e-37 ywtG EGP Major facilitator Superfamily
NPPOIMGL_02639 2.4e-170 ywtF K Transcriptional regulator
NPPOIMGL_02640 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NPPOIMGL_02641 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NPPOIMGL_02642 9e-20 ywtC
NPPOIMGL_02643 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NPPOIMGL_02644 8.6e-70 pgsC S biosynthesis protein
NPPOIMGL_02645 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NPPOIMGL_02646 5.5e-178 rbsR K transcriptional
NPPOIMGL_02647 4.2e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPPOIMGL_02648 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NPPOIMGL_02649 9.8e-272 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NPPOIMGL_02650 7.3e-145 rbsC G Belongs to the binding-protein-dependent transport system permease family
NPPOIMGL_02651 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NPPOIMGL_02652 4e-20 batE T Sh3 type 3 domain protein
NPPOIMGL_02653 3.5e-71 batE T Sh3 type 3 domain protein
NPPOIMGL_02654 8e-48 ywsA S Protein of unknown function (DUF3892)
NPPOIMGL_02655 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NPPOIMGL_02656 2.4e-134 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NPPOIMGL_02657 5.3e-203 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NPPOIMGL_02658 7.3e-125 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NPPOIMGL_02659 1.1e-169 alsR K LysR substrate binding domain
NPPOIMGL_02660 1.5e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NPPOIMGL_02661 1.1e-124 ywrJ
NPPOIMGL_02662 2.6e-125 cotB
NPPOIMGL_02663 6.2e-207 cotH M Spore Coat
NPPOIMGL_02664 1.6e-12
NPPOIMGL_02665 7.2e-100 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NPPOIMGL_02666 1.1e-53 S Domain of unknown function (DUF4181)
NPPOIMGL_02667 1.8e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NPPOIMGL_02668 8e-82 ywrC K Transcriptional regulator
NPPOIMGL_02669 2.7e-103 ywrB P Chromate transporter
NPPOIMGL_02670 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
NPPOIMGL_02672 3.5e-97 ywqN S NAD(P)H-dependent
NPPOIMGL_02673 1.9e-161 K Transcriptional regulator
NPPOIMGL_02674 1.1e-37 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NPPOIMGL_02675 4.7e-115 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NPPOIMGL_02676 5.2e-100
NPPOIMGL_02677 4.2e-62
NPPOIMGL_02678 2.1e-66 fliD N LXG domain of WXG superfamily
NPPOIMGL_02679 2.2e-28 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NPPOIMGL_02680 1.7e-52 S MORN repeat variant
NPPOIMGL_02681 6.4e-142 ywqJ L nucleic acid phosphodiester bond hydrolysis
NPPOIMGL_02682 9e-171 ywqJ L nucleic acid phosphodiester bond hydrolysis
NPPOIMGL_02683 3.1e-38 ywqI S Family of unknown function (DUF5344)
NPPOIMGL_02684 1.7e-19 S Domain of unknown function (DUF5082)
NPPOIMGL_02685 4.4e-26
NPPOIMGL_02686 5.5e-112 ydfB J GNAT acetyltransferase
NPPOIMGL_02687 2.6e-29 ydfB J GNAT acetyltransferase
NPPOIMGL_02688 2.8e-149 lytR K Transcriptional regulator
NPPOIMGL_02689 1e-121 nodB1 G deacetylase
NPPOIMGL_02690 1.5e-158
NPPOIMGL_02691 7.5e-224 T GHKL domain
NPPOIMGL_02692 2e-122 T Transcriptional regulatory protein, C terminal
NPPOIMGL_02693 2.2e-149 ydfC EG EamA-like transporter family
NPPOIMGL_02694 7.9e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPPOIMGL_02695 8.9e-185 gadB 4.1.1.105, 4.1.1.28, 4.1.1.29 E Pyridoxal-dependent decarboxylase conserved domain
NPPOIMGL_02696 3.3e-55 ydfE S Flavin reductase like domain
NPPOIMGL_02697 7e-73 ydfE S Flavin reductase like domain
NPPOIMGL_02698 7.8e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NPPOIMGL_02699 1.1e-77 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NPPOIMGL_02701 4.6e-167 ydfH 2.7.13.3 T Histidine kinase
NPPOIMGL_02702 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPPOIMGL_02703 0.0 ydfJ S drug exporters of the RND superfamily
NPPOIMGL_02704 3.2e-172 S Alpha/beta hydrolase family
NPPOIMGL_02705 1.7e-117 S Protein of unknown function (DUF554)
NPPOIMGL_02706 5.1e-145 K Bacterial transcription activator, effector binding domain
NPPOIMGL_02707 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPPOIMGL_02708 8.9e-12 ydfN C nitroreductase
NPPOIMGL_02709 8.1e-111 ydfN C nitroreductase
NPPOIMGL_02710 6.8e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NPPOIMGL_02711 3.4e-62 mhqP S DoxX
NPPOIMGL_02712 1.7e-54 traF CO Thioredoxin
NPPOIMGL_02713 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NPPOIMGL_02714 4.4e-30
NPPOIMGL_02716 3e-85 ydfR S Protein of unknown function (DUF421)
NPPOIMGL_02718 1.3e-106 ydfS S Protein of unknown function (DUF421)
NPPOIMGL_02719 9e-65 cotP O Belongs to the small heat shock protein (HSP20) family
NPPOIMGL_02720 4.3e-19 ydgA S Spore germination protein gerPA/gerPF
NPPOIMGL_02721 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
NPPOIMGL_02722 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NPPOIMGL_02723 7.6e-98 K Bacterial regulatory proteins, tetR family
NPPOIMGL_02724 1.4e-51 S DoxX-like family
NPPOIMGL_02725 3.8e-14 yycN 2.3.1.128 K Acetyltransferase
NPPOIMGL_02726 2.5e-55 yycN 2.3.1.128 K Acetyltransferase
NPPOIMGL_02727 2.3e-48 FG HIT domain
NPPOIMGL_02729 8e-139 EGP Major facilitator Superfamily
NPPOIMGL_02730 1.1e-48 K Bacterial regulatory proteins, tetR family
NPPOIMGL_02731 1.1e-71 yyaK S CAAX protease self-immunity
NPPOIMGL_02732 4.3e-71 yyaK S CAAX protease self-immunity
NPPOIMGL_02733 3.1e-238 EGP Major facilitator superfamily
NPPOIMGL_02734 3.9e-85 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NPPOIMGL_02735 3.4e-58 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPPOIMGL_02736 1.7e-176 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NPPOIMGL_02737 2.2e-142 xth 3.1.11.2 L exodeoxyribonuclease III
NPPOIMGL_02738 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPPOIMGL_02739 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPPOIMGL_02740 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NPPOIMGL_02741 3.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPPOIMGL_02742 2.5e-175 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPPOIMGL_02743 3.1e-180 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPPOIMGL_02744 2.3e-33 yyzM S protein conserved in bacteria
NPPOIMGL_02745 3.1e-176 yyaD S Membrane
NPPOIMGL_02746 2.8e-94 yyaC S Sporulation protein YyaC
NPPOIMGL_02747 9.8e-61 yyaC S Sporulation protein YyaC
NPPOIMGL_02748 2.1e-149 spo0J K Belongs to the ParB family
NPPOIMGL_02749 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NPPOIMGL_02750 1.3e-73 S Bacterial PH domain
NPPOIMGL_02751 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NPPOIMGL_02752 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NPPOIMGL_02753 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPPOIMGL_02754 3e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPPOIMGL_02755 6.5e-108 jag S single-stranded nucleic acid binding R3H
NPPOIMGL_02756 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPPOIMGL_02757 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPPOIMGL_02758 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPPOIMGL_02759 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPPOIMGL_02760 2.4e-33 yaaA S S4 domain
NPPOIMGL_02761 2.3e-159 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPPOIMGL_02762 2.4e-56 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPPOIMGL_02763 1.8e-37 yaaB S Domain of unknown function (DUF370)
NPPOIMGL_02764 5.2e-122 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPPOIMGL_02765 4.6e-252 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPPOIMGL_02766 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPPOIMGL_02767 2e-44 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPPOIMGL_02768 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NPPOIMGL_02769 6.6e-123 ylaA
NPPOIMGL_02770 6.1e-263 ylaA
NPPOIMGL_02771 6.6e-41 ylaB
NPPOIMGL_02772 1.3e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_02773 1.2e-11 sigC S Putative zinc-finger
NPPOIMGL_02774 2.6e-37 ylaE
NPPOIMGL_02775 8.2e-22 S Family of unknown function (DUF5325)
NPPOIMGL_02776 0.0 typA T GTP-binding protein TypA
NPPOIMGL_02777 4.2e-47 ylaH S YlaH-like protein
NPPOIMGL_02778 2.5e-32 ylaI S protein conserved in bacteria
NPPOIMGL_02779 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPPOIMGL_02780 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NPPOIMGL_02781 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NPPOIMGL_02782 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NPPOIMGL_02783 8.7e-44 ylaN S Belongs to the UPF0358 family
NPPOIMGL_02784 2.1e-211 ftsW D Belongs to the SEDS family
NPPOIMGL_02785 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NPPOIMGL_02786 1.9e-105 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NPPOIMGL_02787 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NPPOIMGL_02788 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NPPOIMGL_02789 1.4e-109 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NPPOIMGL_02790 6.5e-237 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NPPOIMGL_02791 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NPPOIMGL_02792 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NPPOIMGL_02793 4.5e-121 ctaG S cytochrome c oxidase
NPPOIMGL_02794 1.4e-33 ctaG S cytochrome c oxidase
NPPOIMGL_02795 7e-62 ylbA S YugN-like family
NPPOIMGL_02796 2.6e-74 ylbB T COG0517 FOG CBS domain
NPPOIMGL_02797 9.6e-200 ylbC S protein with SCP PR1 domains
NPPOIMGL_02798 1.7e-61 ylbD S Putative coat protein
NPPOIMGL_02799 6.7e-37 ylbE S YlbE-like protein
NPPOIMGL_02800 1.8e-75 ylbF S Belongs to the UPF0342 family
NPPOIMGL_02801 3.7e-38 ylbG S UPF0298 protein
NPPOIMGL_02802 7.8e-97 rsmD 2.1.1.171 L Methyltransferase
NPPOIMGL_02803 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPPOIMGL_02804 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
NPPOIMGL_02805 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
NPPOIMGL_02806 7.5e-186 ylbL T Belongs to the peptidase S16 family
NPPOIMGL_02807 2.1e-230 ylbM S Belongs to the UPF0348 family
NPPOIMGL_02809 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NPPOIMGL_02810 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NPPOIMGL_02811 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NPPOIMGL_02812 4.7e-89 ylbP K n-acetyltransferase
NPPOIMGL_02813 4.4e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPPOIMGL_02814 4.6e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NPPOIMGL_02815 2.9e-78 mraZ K Belongs to the MraZ family
NPPOIMGL_02816 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPPOIMGL_02817 6.4e-44 ftsL D Essential cell division protein
NPPOIMGL_02818 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NPPOIMGL_02819 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NPPOIMGL_02820 1.2e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPPOIMGL_02821 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPPOIMGL_02822 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPPOIMGL_02823 1.9e-198 spoVE D Belongs to the SEDS family
NPPOIMGL_02824 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPPOIMGL_02825 5.3e-167 murB 1.3.1.98 M cell wall formation
NPPOIMGL_02826 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPPOIMGL_02827 2.4e-103 ylxW S protein conserved in bacteria
NPPOIMGL_02828 2.8e-117 ylxX S protein conserved in bacteria
NPPOIMGL_02829 6.2e-58 sbp S small basic protein
NPPOIMGL_02830 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPPOIMGL_02831 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPPOIMGL_02832 1.5e-308 bpr O COG1404 Subtilisin-like serine proteases
NPPOIMGL_02833 6.4e-176 bpr O COG1404 Subtilisin-like serine proteases
NPPOIMGL_02834 3.9e-162 bpr O COG1404 Subtilisin-like serine proteases
NPPOIMGL_02835 1.4e-43 bpr O COG1404 Subtilisin-like serine proteases
NPPOIMGL_02836 8.1e-137 bpr O COG1404 Subtilisin-like serine proteases
NPPOIMGL_02837 1.1e-170 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NPPOIMGL_02838 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPPOIMGL_02839 1.6e-132 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPPOIMGL_02840 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NPPOIMGL_02841 7.1e-250 argE 3.5.1.16 E Acetylornithine deacetylase
NPPOIMGL_02842 2.4e-37 ylmC S sporulation protein
NPPOIMGL_02843 1.7e-123 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NPPOIMGL_02844 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NPPOIMGL_02845 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPPOIMGL_02846 1.6e-39 yggT S membrane
NPPOIMGL_02847 3.3e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NPPOIMGL_02848 2.6e-67 divIVA D Cell division initiation protein
NPPOIMGL_02849 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPPOIMGL_02850 1.3e-63 dksA T COG1734 DnaK suppressor protein
NPPOIMGL_02851 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPPOIMGL_02852 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPPOIMGL_02853 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPPOIMGL_02854 1.9e-229 pyrP F Xanthine uracil
NPPOIMGL_02855 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NPPOIMGL_02856 2.9e-241 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPPOIMGL_02857 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPPOIMGL_02858 4.3e-90 carB 6.3.5.5 F Belongs to the CarB family
NPPOIMGL_02859 4.2e-152 carB 6.3.5.5 F Belongs to the CarB family
NPPOIMGL_02860 0.0 carB 6.3.5.5 F Belongs to the CarB family
NPPOIMGL_02861 2.6e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NPPOIMGL_02862 1.8e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPPOIMGL_02863 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPPOIMGL_02864 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPPOIMGL_02866 1.7e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NPPOIMGL_02867 4.1e-179 cysP P phosphate transporter
NPPOIMGL_02868 6.5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NPPOIMGL_02869 4.6e-100 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NPPOIMGL_02870 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NPPOIMGL_02871 1.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NPPOIMGL_02872 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NPPOIMGL_02873 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NPPOIMGL_02874 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NPPOIMGL_02875 2.4e-156 yloC S stress-induced protein
NPPOIMGL_02876 1.5e-40 ylzA S Belongs to the UPF0296 family
NPPOIMGL_02877 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NPPOIMGL_02878 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPPOIMGL_02879 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPPOIMGL_02880 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPPOIMGL_02881 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPPOIMGL_02882 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPPOIMGL_02883 4.2e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPPOIMGL_02884 5.6e-178 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NPPOIMGL_02885 2.7e-28 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NPPOIMGL_02886 2.3e-139 stp 3.1.3.16 T phosphatase
NPPOIMGL_02887 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NPPOIMGL_02888 1.9e-132 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPPOIMGL_02889 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NPPOIMGL_02890 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NPPOIMGL_02891 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NPPOIMGL_02892 5.5e-59 asp S protein conserved in bacteria
NPPOIMGL_02893 1.1e-300 yloV S kinase related to dihydroxyacetone kinase
NPPOIMGL_02894 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NPPOIMGL_02895 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NPPOIMGL_02896 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPPOIMGL_02897 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NPPOIMGL_02898 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPPOIMGL_02899 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NPPOIMGL_02900 5.1e-128 IQ reductase
NPPOIMGL_02901 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPPOIMGL_02902 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPPOIMGL_02903 0.0 smc D Required for chromosome condensation and partitioning
NPPOIMGL_02904 2e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPPOIMGL_02905 2.9e-87
NPPOIMGL_02906 9.3e-66
NPPOIMGL_02907 2.1e-181 sacB 2.4.1.10 GH68 M levansucrase activity
NPPOIMGL_02908 4.5e-85 sacB 2.4.1.10 GH68 M levansucrase activity
NPPOIMGL_02909 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NPPOIMGL_02910 1.8e-295 yveA E amino acid
NPPOIMGL_02911 9.7e-106 yvdT K Transcriptional regulator
NPPOIMGL_02912 1.5e-50 ykkC P Small Multidrug Resistance protein
NPPOIMGL_02913 5.8e-33 sugE P Small Multidrug Resistance protein
NPPOIMGL_02914 1.9e-30 sugE P Small Multidrug Resistance protein
NPPOIMGL_02915 1.1e-92 yvdQ S Protein of unknown function (DUF3231)
NPPOIMGL_02917 2.3e-173 S Patatin-like phospholipase
NPPOIMGL_02919 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPPOIMGL_02920 4.5e-111 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NPPOIMGL_02921 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NPPOIMGL_02922 1.3e-296 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NPPOIMGL_02923 1.8e-128 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NPPOIMGL_02924 3.5e-71 malA S Protein of unknown function (DUF1189)
NPPOIMGL_02925 1.4e-128 malD P transport
NPPOIMGL_02926 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
NPPOIMGL_02927 1.2e-66 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NPPOIMGL_02928 6.8e-40 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NPPOIMGL_02929 2.1e-119 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NPPOIMGL_02930 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NPPOIMGL_02931 3.6e-174 yvdE K Transcriptional regulator
NPPOIMGL_02932 1.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
NPPOIMGL_02933 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
NPPOIMGL_02934 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NPPOIMGL_02935 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NPPOIMGL_02936 1.8e-178 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPPOIMGL_02937 0.0 yxdM V ABC transporter (permease)
NPPOIMGL_02938 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NPPOIMGL_02939 9.8e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NPPOIMGL_02940 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_02941 2.8e-31
NPPOIMGL_02942 1.5e-32
NPPOIMGL_02943 5.2e-110 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NPPOIMGL_02944 4.1e-43 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NPPOIMGL_02945 1.6e-36 crh G Phosphocarrier protein Chr
NPPOIMGL_02946 1.4e-170 whiA K May be required for sporulation
NPPOIMGL_02947 2.5e-173 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NPPOIMGL_02948 5.7e-166 rapZ S Displays ATPase and GTPase activities
NPPOIMGL_02949 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NPPOIMGL_02950 1.5e-80 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPPOIMGL_02951 1.2e-54 L Recombinase
NPPOIMGL_02952 1.6e-155 pbuX F xanthine
NPPOIMGL_02953 7.4e-206 bcsA Q Naringenin-chalcone synthase
NPPOIMGL_02954 5.1e-87 ypbQ S protein conserved in bacteria
NPPOIMGL_02955 0.0 ypbR S Dynamin family
NPPOIMGL_02956 1e-38 ypbS S Protein of unknown function (DUF2533)
NPPOIMGL_02957 2e-07
NPPOIMGL_02958 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NPPOIMGL_02960 2.1e-67 rnhA 3.1.26.4 L Ribonuclease
NPPOIMGL_02961 1e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NPPOIMGL_02962 4.7e-135 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NPPOIMGL_02963 3e-29 ypeQ S Zinc-finger
NPPOIMGL_02964 8.1e-31 S Protein of unknown function (DUF2564)
NPPOIMGL_02965 3.8e-16 degR
NPPOIMGL_02966 7.9e-31 cspD K Cold-shock protein
NPPOIMGL_02967 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NPPOIMGL_02969 8.1e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NPPOIMGL_02970 1.4e-09 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NPPOIMGL_02971 3.2e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NPPOIMGL_02972 7e-95 ypgQ S phosphohydrolase
NPPOIMGL_02973 1.1e-30 ypgR C COG0694 Thioredoxin-like proteins and domains
NPPOIMGL_02974 1.1e-34 ypgR C COG0694 Thioredoxin-like proteins and domains
NPPOIMGL_02975 4.6e-138 ypgR C COG0694 Thioredoxin-like proteins and domains
NPPOIMGL_02976 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NPPOIMGL_02977 1.7e-75 yphP S Belongs to the UPF0403 family
NPPOIMGL_02978 1e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NPPOIMGL_02979 2.5e-112 ypjP S YpjP-like protein
NPPOIMGL_02980 1.2e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NPPOIMGL_02981 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPPOIMGL_02982 2.1e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPPOIMGL_02983 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NPPOIMGL_02984 4.2e-110 hlyIII S protein, Hemolysin III
NPPOIMGL_02985 1.8e-184 pspF K Transcriptional regulator
NPPOIMGL_02986 4.8e-40 pspF K Transcriptional regulator
NPPOIMGL_02987 3.6e-30 pspF K Transcriptional regulator
NPPOIMGL_02988 8.1e-92 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NPPOIMGL_02989 1.4e-110 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NPPOIMGL_02990 8.9e-40 ypmP S Protein of unknown function (DUF2535)
NPPOIMGL_02991 3.7e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NPPOIMGL_02992 1.1e-133 ypmR E GDSL-like Lipase/Acylhydrolase
NPPOIMGL_02993 1.2e-97 ypmS S protein conserved in bacteria
NPPOIMGL_02994 5.5e-29 ypmT S Uncharacterized ympT
NPPOIMGL_02995 5.5e-221 mepA V MATE efflux family protein
NPPOIMGL_02996 1.6e-70 ypoP K transcriptional
NPPOIMGL_02997 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPPOIMGL_02998 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NPPOIMGL_02999 7.4e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
NPPOIMGL_03000 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NPPOIMGL_03001 1.3e-176 cgeB S Spore maturation protein
NPPOIMGL_03002 8.2e-64 cgeA
NPPOIMGL_03003 1.3e-37 cgeC
NPPOIMGL_03004 6.2e-224 cgeD M maturation of the outermost layer of the spore
NPPOIMGL_03005 2.5e-61 cgeD M maturation of the outermost layer of the spore
NPPOIMGL_03006 8.6e-142 yiiD K acetyltransferase
NPPOIMGL_03008 5.3e-221 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPPOIMGL_03009 7.9e-123 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NPPOIMGL_03010 2.4e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NPPOIMGL_03011 5.1e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
NPPOIMGL_03012 2.3e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NPPOIMGL_03013 4.1e-270 kamA 5.4.3.2 E lysine 2,3-aminomutase
NPPOIMGL_03014 2.9e-47 yokU S YokU-like protein, putative antitoxin
NPPOIMGL_03015 1.4e-36 yozE S Belongs to the UPF0346 family
NPPOIMGL_03016 6e-123 yodN
NPPOIMGL_03018 2.8e-24 yozD S YozD-like protein
NPPOIMGL_03019 1.6e-106 yodM 3.6.1.27 I Acid phosphatase homologues
NPPOIMGL_03020 3.6e-54 yodL S YodL-like
NPPOIMGL_03021 5.3e-09
NPPOIMGL_03022 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NPPOIMGL_03023 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NPPOIMGL_03024 1.5e-23 yodI
NPPOIMGL_03025 6.3e-128 yodH Q Methyltransferase
NPPOIMGL_03026 1.1e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NPPOIMGL_03027 5.2e-119 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPPOIMGL_03028 5.7e-90 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPPOIMGL_03029 7.4e-113 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPPOIMGL_03030 1.2e-18 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPPOIMGL_03031 1.5e-14 S Protein of unknown function (DUF3311)
NPPOIMGL_03032 9.3e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
NPPOIMGL_03033 3.9e-57 mhqD S Carboxylesterase
NPPOIMGL_03034 6.7e-56 mhqD S Carboxylesterase
NPPOIMGL_03035 4.8e-108 yodC C nitroreductase
NPPOIMGL_03036 4.4e-55 yodB K transcriptional
NPPOIMGL_03037 8e-64 yodA S tautomerase
NPPOIMGL_03038 4.6e-40 gntP EG COG2610 H gluconate symporter and related permeases
NPPOIMGL_03039 6.7e-36 gntT EG COG2610 H gluconate symporter and related permeases
NPPOIMGL_03040 2.6e-73 gntP EG COG2610 H gluconate symporter and related permeases
NPPOIMGL_03041 2e-78 gntP EG COG2610 H gluconate symporter and related permeases
NPPOIMGL_03042 3.4e-09
NPPOIMGL_03043 6.5e-37 yozR S COG0071 Molecular chaperone (small heat shock protein)
NPPOIMGL_03044 2.3e-31 yozR S COG0071 Molecular chaperone (small heat shock protein)
NPPOIMGL_03045 6.6e-162 rarD S -transporter
NPPOIMGL_03046 1.5e-43
NPPOIMGL_03047 2.2e-60 yojF S Protein of unknown function (DUF1806)
NPPOIMGL_03048 2.1e-125 yojG S deacetylase
NPPOIMGL_03049 4.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPPOIMGL_03050 1.2e-86 norM V Multidrug efflux pump
NPPOIMGL_03051 4.9e-95 yfmO EGP Major facilitator Superfamily
NPPOIMGL_03052 2.4e-69 yfmP K transcriptional
NPPOIMGL_03053 4.9e-73 yfmQ S Uncharacterised protein from bacillus cereus group
NPPOIMGL_03054 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPPOIMGL_03055 2.4e-47 yfmS NT chemotaxis protein
NPPOIMGL_03056 5.4e-39 yfmS NT chemotaxis protein
NPPOIMGL_03057 3.1e-62 yfmS NT chemotaxis protein
NPPOIMGL_03058 2.2e-37 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPPOIMGL_03059 6e-213 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPPOIMGL_03060 3.1e-55 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPPOIMGL_03061 1.4e-240 yfnA E amino acid
NPPOIMGL_03062 9.5e-96 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPPOIMGL_03063 8.5e-40 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPPOIMGL_03064 5.1e-205 fsr P COG0477 Permeases of the major facilitator superfamily
NPPOIMGL_03065 1.2e-187 yfnD M Nucleotide-diphospho-sugar transferase
NPPOIMGL_03066 6e-199 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NPPOIMGL_03067 1.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
NPPOIMGL_03068 3.2e-172 yfnG 4.2.1.45 M dehydratase
NPPOIMGL_03069 1.5e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
NPPOIMGL_03070 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NPPOIMGL_03071 2.5e-71 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NPPOIMGL_03072 3.7e-126 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NPPOIMGL_03073 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NPPOIMGL_03074 3.4e-197 yetN S Protein of unknown function (DUF3900)
NPPOIMGL_03075 1.4e-236 mobC K Transcriptional regulator
NPPOIMGL_03076 2.2e-11 yetM CH FAD binding domain
NPPOIMGL_03077 5.3e-105 yetJ S Belongs to the BI1 family
NPPOIMGL_03078 2.6e-19 yezD S Uncharacterized small protein (DUF2292)
NPPOIMGL_03079 8.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPPOIMGL_03081 8.7e-19 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPPOIMGL_03082 2.1e-27 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPPOIMGL_03083 1.3e-13 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NPPOIMGL_03084 5.3e-53 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NPPOIMGL_03085 1.2e-108 yetF S membrane
NPPOIMGL_03086 1.1e-234 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NPPOIMGL_03087 4.7e-149 lplC G Binding-protein-dependent transport system inner membrane component
NPPOIMGL_03088 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NPPOIMGL_03089 6.2e-290 lplA G Bacterial extracellular solute-binding protein
NPPOIMGL_03090 1.9e-143 yetA
NPPOIMGL_03091 2.2e-245 yetA
NPPOIMGL_03092 1.7e-41 yetA
NPPOIMGL_03093 2.8e-103 yetA
NPPOIMGL_03094 4.6e-57 yetA
NPPOIMGL_03095 6e-63 yetA
NPPOIMGL_03096 6.8e-104 yesZ 3.2.1.23 G beta-galactosidase activity
NPPOIMGL_03097 4.7e-247 yesZ 3.2.1.23 G beta-galactosidase activity
NPPOIMGL_03098 2e-67 yesZ 3.2.1.23 G beta-galactosidase activity
NPPOIMGL_03099 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
NPPOIMGL_03100 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NPPOIMGL_03101 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NPPOIMGL_03102 3e-113 yesV S Protein of unknown function, DUF624
NPPOIMGL_03103 1.2e-128 yesU S Domain of unknown function (DUF1961)
NPPOIMGL_03104 3.8e-133 E GDSL-like Lipase/Acylhydrolase
NPPOIMGL_03105 8.9e-256 yesS K Transcriptional regulator
NPPOIMGL_03106 4.4e-130 yesS K Transcriptional regulator
NPPOIMGL_03107 4.6e-189 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NPPOIMGL_03108 2.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
NPPOIMGL_03109 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
NPPOIMGL_03110 1.5e-247 yesO G Bacterial extracellular solute-binding protein
NPPOIMGL_03111 2.1e-76 yesN K helix_turn_helix, arabinose operon control protein
NPPOIMGL_03112 8.9e-45 yesN K helix_turn_helix, arabinose operon control protein
NPPOIMGL_03113 3.7e-88 yesN K helix_turn_helix, arabinose operon control protein
NPPOIMGL_03114 7.5e-267 yesM 2.7.13.3 T Histidine kinase
NPPOIMGL_03115 1.8e-102 yesL S Protein of unknown function, DUF624
NPPOIMGL_03116 2.4e-65 yesJ K Acetyltransferase (GNAT) family
NPPOIMGL_03117 5.2e-104 cotJC P Spore Coat
NPPOIMGL_03118 1.5e-45 cotJB S CotJB protein
NPPOIMGL_03119 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NPPOIMGL_03120 1e-136 yesF GM NAD(P)H-binding
NPPOIMGL_03121 3.1e-80 yesE S SnoaL-like domain
NPPOIMGL_03122 9.4e-101 dhaR3 K Transcriptional regulator
NPPOIMGL_03124 1.2e-13 yeeN K transcriptional regulatory protein
NPPOIMGL_03125 2.1e-103 yeeN K transcriptional regulatory protein
NPPOIMGL_03127 8.9e-167 S Tetratricopeptide repeat
NPPOIMGL_03128 9.6e-85 yfjM S Psort location Cytoplasmic, score
NPPOIMGL_03129 1.9e-11 yfjM S Psort location Cytoplasmic, score
NPPOIMGL_03130 1.7e-96 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPPOIMGL_03131 7.9e-82 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPPOIMGL_03132 3.1e-53 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPPOIMGL_03133 3.9e-44 S YfzA-like protein
NPPOIMGL_03134 5.3e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPPOIMGL_03135 8.7e-147
NPPOIMGL_03136 1.5e-166 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NPPOIMGL_03137 1.7e-184 corA P Mediates influx of magnesium ions
NPPOIMGL_03138 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NPPOIMGL_03139 2.6e-154 pdaA G deacetylase
NPPOIMGL_03140 1.1e-26 yfjT
NPPOIMGL_03141 5.4e-222 yfkA S YfkB-like domain
NPPOIMGL_03142 6e-149 yfkC M Mechanosensitive ion channel
NPPOIMGL_03143 1.2e-146 yfkD S YfkD-like protein
NPPOIMGL_03144 6.1e-183 cax P COG0387 Ca2 H antiporter
NPPOIMGL_03145 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NPPOIMGL_03146 5e-08
NPPOIMGL_03147 1.3e-143 yihY S Belongs to the UPF0761 family
NPPOIMGL_03148 4.1e-50 yfkI S gas vesicle protein
NPPOIMGL_03149 3.8e-41 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPPOIMGL_03150 8.2e-09 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPPOIMGL_03151 2.1e-29 yfkK S Belongs to the UPF0435 family
NPPOIMGL_03152 8.9e-207 ydiM EGP Major facilitator Superfamily
NPPOIMGL_03153 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
NPPOIMGL_03154 1.2e-131 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NPPOIMGL_03155 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NPPOIMGL_03156 1.2e-73 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
NPPOIMGL_03157 1.3e-149 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NPPOIMGL_03158 5e-27 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NPPOIMGL_03159 1.1e-124 yfkO C nitroreductase
NPPOIMGL_03160 1.8e-133 treR K transcriptional
NPPOIMGL_03161 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NPPOIMGL_03162 5.3e-249 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPPOIMGL_03163 2.2e-25 yfkQ EG Spore germination protein
NPPOIMGL_03164 1.5e-192 agcS_1 E Sodium alanine symporter
NPPOIMGL_03165 3.3e-41 agcS_1 E Sodium alanine symporter
NPPOIMGL_03166 6e-67 yhdN S Domain of unknown function (DUF1992)
NPPOIMGL_03167 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NPPOIMGL_03168 2.6e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NPPOIMGL_03169 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NPPOIMGL_03170 4.5e-49 yflH S Protein of unknown function (DUF3243)
NPPOIMGL_03171 9.1e-19 yflI
NPPOIMGL_03172 4e-18 yflJ S Protein of unknown function (DUF2639)
NPPOIMGL_03173 1.1e-121 yflK S protein conserved in bacteria
NPPOIMGL_03174 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NPPOIMGL_03175 7.4e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NPPOIMGL_03176 2.1e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NPPOIMGL_03177 5.5e-226 citM C Citrate transporter
NPPOIMGL_03178 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
NPPOIMGL_03179 8.9e-119 citT T response regulator
NPPOIMGL_03180 1.8e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NPPOIMGL_03181 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
NPPOIMGL_03182 8.5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NPPOIMGL_03183 7.6e-58 yflT S Heat induced stress protein YflT
NPPOIMGL_03184 5.3e-14 S Protein of unknown function (DUF3212)
NPPOIMGL_03185 1.2e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NPPOIMGL_03186 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_03187 5.8e-167 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_03188 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NPPOIMGL_03189 7.9e-188 yfmJ S N-terminal domain of oxidoreductase
NPPOIMGL_03190 1.8e-75 yfmK 2.3.1.128 K acetyltransferase
NPPOIMGL_03191 2e-195 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NPPOIMGL_03192 3.1e-190 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPPOIMGL_03193 1.2e-82 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPPOIMGL_03194 6e-51 ywbC 4.4.1.5 E glyoxalase
NPPOIMGL_03195 4.5e-123 ywbB S Protein of unknown function (DUF2711)
NPPOIMGL_03196 2.1e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPPOIMGL_03197 4.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
NPPOIMGL_03198 2.6e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPPOIMGL_03199 4e-153 sacY K transcriptional antiterminator
NPPOIMGL_03200 4.5e-168 gspA M General stress
NPPOIMGL_03201 3.7e-123 ywaF S Integral membrane protein
NPPOIMGL_03202 4e-87 ywaE K Transcriptional regulator
NPPOIMGL_03203 5e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPPOIMGL_03204 2.9e-244 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NPPOIMGL_03205 5.3e-92 K Helix-turn-helix XRE-family like proteins
NPPOIMGL_03206 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
NPPOIMGL_03207 5.2e-130 ynfM EGP Major facilitator Superfamily
NPPOIMGL_03208 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NPPOIMGL_03209 3.5e-166 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NPPOIMGL_03210 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
NPPOIMGL_03211 2.6e-286 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_03212 3.8e-207 dltB M membrane protein involved in D-alanine export
NPPOIMGL_03213 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_03214 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPPOIMGL_03215 3.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_03216 2.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NPPOIMGL_03217 6e-199 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NPPOIMGL_03218 5.2e-43 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NPPOIMGL_03219 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NPPOIMGL_03220 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPPOIMGL_03221 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NPPOIMGL_03222 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NPPOIMGL_03223 1.1e-19 yxzF
NPPOIMGL_03224 8.8e-83 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NPPOIMGL_03225 1.2e-13 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NPPOIMGL_03226 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NPPOIMGL_03227 4.6e-211 yxlH EGP Major facilitator Superfamily
NPPOIMGL_03228 1.2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NPPOIMGL_03229 6.3e-165 yxlF V ABC transporter, ATP-binding protein
NPPOIMGL_03230 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NPPOIMGL_03231 2.2e-28
NPPOIMGL_03232 3e-25 yxlC S Family of unknown function (DUF5345)
NPPOIMGL_03233 3.6e-11 yxlC S Family of unknown function (DUF5345)
NPPOIMGL_03234 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_03235 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NPPOIMGL_03236 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPPOIMGL_03237 8.6e-123 cydD V ATP-binding protein
NPPOIMGL_03238 1.4e-171 cydD V ATP-binding protein
NPPOIMGL_03239 9.2e-89 cydD V ATP-binding
NPPOIMGL_03240 8.3e-146 cydD V ATP-binding
NPPOIMGL_03241 1.6e-39 cydD V ATP-binding
NPPOIMGL_03242 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NPPOIMGL_03243 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
NPPOIMGL_03244 1.5e-229 cimH C COG3493 Na citrate symporter
NPPOIMGL_03245 5e-24 3.4.24.84 O Peptidase family M48
NPPOIMGL_03246 1.2e-286 3.4.24.84 O Peptidase family M48
NPPOIMGL_03249 1.8e-78 yxkH G Polysaccharide deacetylase
NPPOIMGL_03250 8.3e-57 yxkH G Polysaccharide deacetylase
NPPOIMGL_03251 1.3e-23 yxkH G Polysaccharide deacetylase
NPPOIMGL_03252 4e-14 yxkH G Polysaccharide deacetylase
NPPOIMGL_03253 8.2e-111 msmK P Belongs to the ABC transporter superfamily
NPPOIMGL_03254 3.9e-123 msmK P Belongs to the ABC transporter superfamily
NPPOIMGL_03255 2e-156 lrp QT PucR C-terminal helix-turn-helix domain
NPPOIMGL_03256 5.6e-39 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPPOIMGL_03257 6.2e-39 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPPOIMGL_03258 6.7e-64 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPPOIMGL_03259 5.3e-181 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPPOIMGL_03260 1.1e-72 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPPOIMGL_03261 1.1e-70 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPPOIMGL_03262 9.3e-41 yxkC S Domain of unknown function (DUF4352)
NPPOIMGL_03263 5.2e-21 yxkC S Domain of unknown function (DUF4352)
NPPOIMGL_03264 2.5e-59 yxkC S Domain of unknown function (DUF4352)
NPPOIMGL_03265 8.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NPPOIMGL_03266 4.4e-63 S Protein of unknown function (DUF1453)
NPPOIMGL_03267 3.1e-24 yxjM T Signal transduction histidine kinase
NPPOIMGL_03268 4.5e-172 yxjM T Signal transduction histidine kinase
NPPOIMGL_03269 3.4e-115 K helix_turn_helix, Lux Regulon
NPPOIMGL_03270 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPPOIMGL_03273 1.3e-84 yxjI S LURP-one-related
NPPOIMGL_03274 3.6e-101 yxjG 2.1.1.14 E Methionine synthase
NPPOIMGL_03275 3e-116 yxjG 2.1.1.14 E Methionine synthase
NPPOIMGL_03276 4.5e-28 yxjG 2.1.1.14 E Methionine synthase
NPPOIMGL_03277 7.6e-103 yxjG 2.1.1.14 E Methionine synthase
NPPOIMGL_03278 1.9e-52 yxjG 2.1.1.14 E Methionine synthase
NPPOIMGL_03279 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NPPOIMGL_03280 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NPPOIMGL_03281 2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NPPOIMGL_03282 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NPPOIMGL_03283 3.2e-158 rlmA 2.1.1.187 Q Methyltransferase domain
NPPOIMGL_03284 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPPOIMGL_03285 2.3e-103 T Domain of unknown function (DUF4163)
NPPOIMGL_03286 3e-47 yxiS
NPPOIMGL_03287 1.5e-305 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NPPOIMGL_03288 1.7e-100 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NPPOIMGL_03289 2.9e-212 citH C Citrate transporter
NPPOIMGL_03290 1.2e-142 exoK GH16 M licheninase activity
NPPOIMGL_03291 2.8e-45 licT K transcriptional antiterminator
NPPOIMGL_03292 6.4e-62 licT K transcriptional antiterminator
NPPOIMGL_03293 1.9e-105
NPPOIMGL_03294 6e-60 yxiO S COG2270 Permeases of the major facilitator superfamily
NPPOIMGL_03295 3e-120 yxiO S COG2270 Permeases of the major facilitator superfamily
NPPOIMGL_03296 5.2e-60 yxiO S COG2270 Permeases of the major facilitator superfamily
NPPOIMGL_03297 3.9e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NPPOIMGL_03298 1.8e-99 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NPPOIMGL_03299 1.9e-122 ybbM S transport system, permease component
NPPOIMGL_03300 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NPPOIMGL_03301 1.1e-114 yjlA EG Putative multidrug resistance efflux transporter
NPPOIMGL_03303 3.4e-91 yjlB S Cupin domain
NPPOIMGL_03304 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NPPOIMGL_03305 8.5e-218 yjlD 1.6.99.3 C NADH dehydrogenase
NPPOIMGL_03306 9.8e-194 uxaC 5.3.1.12 G glucuronate isomerase
NPPOIMGL_03307 3.6e-137 uxaC 5.3.1.12 G glucuronate isomerase
NPPOIMGL_03308 1.6e-247 yjmB G symporter YjmB
NPPOIMGL_03309 1.4e-178 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NPPOIMGL_03310 2.1e-20 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NPPOIMGL_03311 1.2e-112 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NPPOIMGL_03312 1.1e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NPPOIMGL_03313 3.6e-108 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_03314 4.1e-226 exuT G Sugar (and other) transporter
NPPOIMGL_03315 1.1e-113 exuR K transcriptional
NPPOIMGL_03316 5.8e-77 exuR K transcriptional
NPPOIMGL_03317 1.6e-269 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NPPOIMGL_03318 4.7e-238 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NPPOIMGL_03319 2.2e-84 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NPPOIMGL_03320 7.4e-130 MA20_18170 S membrane transporter protein
NPPOIMGL_03321 2.3e-78 yjoA S DinB family
NPPOIMGL_03322 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NPPOIMGL_03323 1e-212 S response regulator aspartate phosphatase
NPPOIMGL_03325 5.2e-37 S YCII-related domain
NPPOIMGL_03326 7e-10 S YCII-related domain
NPPOIMGL_03327 2.7e-169 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NPPOIMGL_03328 1.8e-60 yjqA S Bacterial PH domain
NPPOIMGL_03329 2.1e-42 yjqB S Pfam:DUF867
NPPOIMGL_03330 5.2e-120 ydbD P Catalase
NPPOIMGL_03331 1.2e-79 xkdA E IrrE N-terminal-like domain
NPPOIMGL_03332 2.3e-110 xkdA E IrrE N-terminal-like domain
NPPOIMGL_03333 9.2e-56 xre K Helix-turn-helix XRE-family like proteins
NPPOIMGL_03335 5e-156 xkdB K sequence-specific DNA binding
NPPOIMGL_03336 1.2e-117 xkdC L Bacterial dnaA protein
NPPOIMGL_03340 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NPPOIMGL_03341 7e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NPPOIMGL_03342 1.5e-181 xtmB S phage terminase, large subunit
NPPOIMGL_03343 2.1e-67 xtmB S phage terminase, large subunit
NPPOIMGL_03344 2.2e-89 yqbA S portal protein
NPPOIMGL_03345 2.2e-193 yqbA S portal protein
NPPOIMGL_03346 1.1e-161 xkdG S Phage capsid family
NPPOIMGL_03347 3.3e-62 yqbG S Protein of unknown function (DUF3199)
NPPOIMGL_03348 7.3e-64 yqbH S Domain of unknown function (DUF3599)
NPPOIMGL_03349 8.4e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
NPPOIMGL_03350 1.9e-77 xkdJ
NPPOIMGL_03351 5.5e-256 xkdK S Phage tail sheath C-terminal domain
NPPOIMGL_03352 7.4e-226 pbuX F Permease family
NPPOIMGL_03353 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
NPPOIMGL_03354 2.3e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NPPOIMGL_03355 1.4e-59 yunG
NPPOIMGL_03356 4.3e-171 yunF S Protein of unknown function DUF72
NPPOIMGL_03357 4.5e-141 yunE S membrane transporter protein
NPPOIMGL_03358 7.4e-211 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPPOIMGL_03359 3.8e-47 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPPOIMGL_03360 3.1e-47 yunC S Domain of unknown function (DUF1805)
NPPOIMGL_03361 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
NPPOIMGL_03362 4.5e-196 lytH M Peptidase, M23
NPPOIMGL_03363 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NPPOIMGL_03364 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPPOIMGL_03365 9.7e-48 yutD S protein conserved in bacteria
NPPOIMGL_03366 8.6e-75 yutE S Protein of unknown function DUF86
NPPOIMGL_03367 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPPOIMGL_03368 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NPPOIMGL_03369 3.9e-60 yutH S Spore coat protein
NPPOIMGL_03370 2.8e-142 yutH S Spore coat protein
NPPOIMGL_03371 1.8e-240 hom 1.1.1.3 E homoserine dehydrogenase
NPPOIMGL_03372 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NPPOIMGL_03373 4.3e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPPOIMGL_03374 1.5e-135 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NPPOIMGL_03375 1.7e-187 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NPPOIMGL_03376 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NPPOIMGL_03377 1.1e-55 yuzD S protein conserved in bacteria
NPPOIMGL_03378 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NPPOIMGL_03379 1.2e-38 yuzB S Belongs to the UPF0349 family
NPPOIMGL_03380 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPPOIMGL_03381 1.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPPOIMGL_03382 3.7e-63 erpA S Belongs to the HesB IscA family
NPPOIMGL_03383 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPPOIMGL_03384 3.2e-115 paiB K Putative FMN-binding domain
NPPOIMGL_03385 9.4e-133 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPPOIMGL_03386 6.2e-35 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPPOIMGL_03388 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
NPPOIMGL_03389 1.4e-220 yumB 1.6.99.3 C NADH dehydrogenase
NPPOIMGL_03390 1.5e-39 yumB 1.6.99.3 C NADH dehydrogenase
NPPOIMGL_03391 8.4e-27 yuiB S Putative membrane protein
NPPOIMGL_03392 8e-117 yuiC S protein conserved in bacteria
NPPOIMGL_03393 1.2e-77 yuiD S protein conserved in bacteria
NPPOIMGL_03394 1.3e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NPPOIMGL_03395 3.9e-211 yuiF S antiporter
NPPOIMGL_03396 5.7e-93 bioY S Biotin biosynthesis protein
NPPOIMGL_03397 6.4e-121 yuiH S Oxidoreductase molybdopterin binding domain
NPPOIMGL_03398 3.4e-163 besA S Putative esterase
NPPOIMGL_03399 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_03400 8.1e-224 entC 5.4.4.2 HQ Isochorismate synthase
NPPOIMGL_03401 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NPPOIMGL_03402 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NPPOIMGL_03403 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_03404 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_03405 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_03406 8.5e-36 mbtH S MbtH-like protein
NPPOIMGL_03407 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NPPOIMGL_03408 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NPPOIMGL_03409 5.3e-218 yukF QT Transcriptional regulator
NPPOIMGL_03410 2.8e-45 esxA S Belongs to the WXG100 family
NPPOIMGL_03411 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NPPOIMGL_03412 3.7e-209 essB S WXG100 protein secretion system (Wss), protein YukC
NPPOIMGL_03413 2e-34 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPPOIMGL_03414 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPPOIMGL_03415 2.7e-67 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPPOIMGL_03416 9.3e-68 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NPPOIMGL_03418 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NPPOIMGL_03419 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NPPOIMGL_03421 3.8e-08 ywlA S Uncharacterised protein family (UPF0715)
NPPOIMGL_03422 5.7e-07 S HIRAN domain
NPPOIMGL_03425 7.3e-116
NPPOIMGL_03427 4.9e-63 yoaQ S Evidence 4 Homologs of previously reported genes of
NPPOIMGL_03428 1.4e-24 yoqW S Belongs to the SOS response-associated peptidase family
NPPOIMGL_03430 6.9e-92 S aspartate phosphatase
NPPOIMGL_03432 6.9e-19
NPPOIMGL_03433 2.6e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NPPOIMGL_03434 1.4e-44 yokH G SMI1 / KNR4 family
NPPOIMGL_03435 6.2e-279 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NPPOIMGL_03436 0.0 yobO M Pectate lyase superfamily protein
NPPOIMGL_03437 3.5e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NPPOIMGL_03438 7.2e-135 yobQ K helix_turn_helix, arabinose operon control protein
NPPOIMGL_03439 7.7e-140 yobR 2.3.1.1 J FR47-like protein
NPPOIMGL_03440 1.4e-96 yobS K Transcriptional regulator
NPPOIMGL_03441 7.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NPPOIMGL_03442 3.5e-78 yobU K Bacterial transcription activator, effector binding domain
NPPOIMGL_03443 7.9e-167 yobV K WYL domain
NPPOIMGL_03444 5.2e-11 yobV K WYL domain
NPPOIMGL_03445 1.8e-90 yobW
NPPOIMGL_03446 8.4e-51 czrA K transcriptional
NPPOIMGL_03447 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NPPOIMGL_03448 1.5e-92 yozB S membrane
NPPOIMGL_03449 2.7e-133
NPPOIMGL_03450 8e-93 yocC
NPPOIMGL_03451 4.9e-25 yocD 3.4.17.13 V peptidase S66
NPPOIMGL_03452 4.2e-186 yocD 3.4.17.13 V peptidase S66
NPPOIMGL_03453 1.5e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NPPOIMGL_03454 7.1e-198 desK 2.7.13.3 T Histidine kinase
NPPOIMGL_03455 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPPOIMGL_03457 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NPPOIMGL_03458 0.0 recQ 3.6.4.12 L DNA helicase
NPPOIMGL_03459 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NPPOIMGL_03460 3.3e-83 dksA T general stress protein
NPPOIMGL_03461 3.4e-18 dksA T general stress protein
NPPOIMGL_03462 3.4e-29 yocL
NPPOIMGL_03463 6.2e-32
NPPOIMGL_03464 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NPPOIMGL_03465 5.9e-35 yocN
NPPOIMGL_03466 4.2e-56 yozO S Bacterial PH domain
NPPOIMGL_03467 2.7e-31 yozC
NPPOIMGL_03468 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NPPOIMGL_03469 2.6e-194 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NPPOIMGL_03470 5.1e-179 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NPPOIMGL_03471 6e-165 sodA 1.15.1.1 P Superoxide dismutase
NPPOIMGL_03472 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NPPOIMGL_03473 2.1e-53 yocS S -transporter
NPPOIMGL_03474 1.7e-108 yfiR K Transcriptional regulator
NPPOIMGL_03475 1.4e-194 yfiS EGP Major facilitator Superfamily
NPPOIMGL_03476 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
NPPOIMGL_03477 2.3e-76 yfiU EGP Major facilitator Superfamily
NPPOIMGL_03478 2.4e-225 yfiU EGP Major facilitator Superfamily
NPPOIMGL_03479 1.4e-78 yfiV K transcriptional
NPPOIMGL_03480 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPPOIMGL_03481 5.4e-59 yfiY P ABC transporter substrate-binding protein
NPPOIMGL_03482 7.7e-100 yfiY P ABC transporter substrate-binding protein
NPPOIMGL_03483 1.2e-92 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_03484 2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_03485 1.5e-86 yfhB 5.3.3.17 S PhzF family
NPPOIMGL_03486 2e-61 yfhB 5.3.3.17 S PhzF family
NPPOIMGL_03487 1.1e-106 yfhC C nitroreductase
NPPOIMGL_03488 8e-25 yfhD S YfhD-like protein
NPPOIMGL_03490 1.6e-114 yfhF S nucleoside-diphosphate sugar epimerase
NPPOIMGL_03491 1.8e-89 yfhF S nucleoside-diphosphate sugar epimerase
NPPOIMGL_03492 9.7e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NPPOIMGL_03493 1.7e-51 yfhH S Protein of unknown function (DUF1811)
NPPOIMGL_03495 3.1e-184 yfhI EGP Major facilitator Superfamily
NPPOIMGL_03496 6.2e-20 sspK S reproduction
NPPOIMGL_03497 1.3e-44 yfhJ S WVELL protein
NPPOIMGL_03498 9.3e-44 batE T Bacterial SH3 domain homologues
NPPOIMGL_03499 2.5e-29 batE T Bacterial SH3 domain homologues
NPPOIMGL_03500 2e-49 batE T Bacterial SH3 domain homologues
NPPOIMGL_03501 1e-47 yfhL S SdpI/YhfL protein family
NPPOIMGL_03502 2.5e-169 yfhM S Alpha beta hydrolase
NPPOIMGL_03503 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NPPOIMGL_03504 1.1e-243 yfhO S Bacterial membrane protein YfhO
NPPOIMGL_03505 1.1e-231 yfhO S Bacterial membrane protein YfhO
NPPOIMGL_03506 1.4e-83 yfhP S membrane-bound metal-dependent
NPPOIMGL_03507 1e-72 yfhP S membrane-bound metal-dependent
NPPOIMGL_03508 3.3e-210 mutY L A G-specific
NPPOIMGL_03509 6.9e-36 yfhS
NPPOIMGL_03510 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_03511 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NPPOIMGL_03512 4.9e-48 ygaB S YgaB-like protein
NPPOIMGL_03513 1.3e-104 ygaC J Belongs to the UPF0374 family
NPPOIMGL_03514 1.8e-301 ygaD V ABC transporter
NPPOIMGL_03515 7.1e-101 ygaE S Membrane
NPPOIMGL_03516 2e-100 ygaE S Membrane
NPPOIMGL_03517 5.8e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NPPOIMGL_03518 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
NPPOIMGL_03519 4e-80 perR P Belongs to the Fur family
NPPOIMGL_03520 9.5e-56 ygzB S UPF0295 protein
NPPOIMGL_03521 2.5e-166 ygxA S Nucleotidyltransferase-like
NPPOIMGL_03522 3.8e-16 K Helix-turn-helix domain
NPPOIMGL_03524 9.9e-46 M D-alanyl-D-alanine carboxypeptidase
NPPOIMGL_03525 1.1e-44 S Bacteriophage holin family
NPPOIMGL_03528 2.8e-73 S Domain of unknown function (DUF2479)
NPPOIMGL_03529 9.2e-104 E GDSL-like Lipase/Acylhydrolase family
NPPOIMGL_03531 7.4e-41 S Prophage endopeptidase tail
NPPOIMGL_03532 6.4e-50 S Phage tail protein
NPPOIMGL_03533 3.8e-64 M phage tail tape measure protein
NPPOIMGL_03537 1.5e-29 S Phage tail tube protein
NPPOIMGL_03539 1.3e-11 S Bacteriophage HK97-gp10, putative tail-component
NPPOIMGL_03541 1.4e-21 L Phage gp6-like head-tail connector protein
NPPOIMGL_03542 6.6e-117 S Phage capsid family
NPPOIMGL_03543 3e-72 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NPPOIMGL_03544 4.9e-83 S Phage portal protein
NPPOIMGL_03545 1.8e-280 S Terminase
NPPOIMGL_03546 3.3e-45 L phage terminase small subunit
NPPOIMGL_03547 3.5e-30 L HNH endonuclease
NPPOIMGL_03551 2.7e-44
NPPOIMGL_03560 6.9e-51 K BRO family, N-terminal domain
NPPOIMGL_03561 4e-22 K BRO family, N-terminal domain
NPPOIMGL_03562 2.7e-195
NPPOIMGL_03563 6.5e-47
NPPOIMGL_03566 6.6e-91 S serine-type endopeptidase activity
NPPOIMGL_03568 4.6e-52
NPPOIMGL_03569 3e-39 S DNA binding
NPPOIMGL_03570 8.1e-11 K Helix-turn-helix domain
NPPOIMGL_03571 3.3e-28 K Helix-turn-helix XRE-family like proteins
NPPOIMGL_03572 2.4e-71 L Phage integrase family
NPPOIMGL_03573 6.2e-192
NPPOIMGL_03574 1.2e-34
NPPOIMGL_03577 1.4e-72 S serine-type endopeptidase activity
NPPOIMGL_03579 2.1e-49
NPPOIMGL_03581 8.9e-63 pbuX F xanthine
NPPOIMGL_03582 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPPOIMGL_03583 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NPPOIMGL_03584 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NPPOIMGL_03585 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NPPOIMGL_03586 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NPPOIMGL_03587 4.4e-186 ptxS K transcriptional
NPPOIMGL_03588 6.5e-152 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NPPOIMGL_03589 2.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_03590 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NPPOIMGL_03592 5.8e-50 yqgA
NPPOIMGL_03593 1.1e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NPPOIMGL_03594 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPPOIMGL_03595 8.4e-91 ypsA S Belongs to the UPF0398 family
NPPOIMGL_03596 5.6e-236 yprB L RNase_H superfamily
NPPOIMGL_03597 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NPPOIMGL_03598 1.5e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NPPOIMGL_03599 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
NPPOIMGL_03600 1e-47 yppG S YppG-like protein
NPPOIMGL_03602 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
NPPOIMGL_03605 2e-185 yppC S Protein of unknown function (DUF2515)
NPPOIMGL_03606 4.6e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPPOIMGL_03607 1.5e-201 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NPPOIMGL_03608 3e-229 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NPPOIMGL_03609 1e-70 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NPPOIMGL_03610 4.7e-93 ypoC
NPPOIMGL_03611 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPPOIMGL_03612 5.7e-129 dnaD L DNA replication protein DnaD
NPPOIMGL_03613 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NPPOIMGL_03614 2.8e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NPPOIMGL_03615 2.2e-79 ypmB S protein conserved in bacteria
NPPOIMGL_03616 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NPPOIMGL_03617 3.8e-190 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NPPOIMGL_03618 1e-309 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NPPOIMGL_03619 1.4e-47 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NPPOIMGL_03620 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NPPOIMGL_03621 1e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NPPOIMGL_03622 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NPPOIMGL_03623 3.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPPOIMGL_03624 7.5e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPPOIMGL_03625 7.7e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NPPOIMGL_03626 1.9e-127 bshB1 S proteins, LmbE homologs
NPPOIMGL_03627 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NPPOIMGL_03628 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPPOIMGL_03629 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NPPOIMGL_03630 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NPPOIMGL_03631 1e-142 ypjB S sporulation protein
NPPOIMGL_03632 3.4e-98 ypjA S membrane
NPPOIMGL_03633 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NPPOIMGL_03634 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NPPOIMGL_03635 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NPPOIMGL_03636 6.1e-76 ypiF S Protein of unknown function (DUF2487)
NPPOIMGL_03637 8.1e-99 ypiB S Belongs to the UPF0302 family
NPPOIMGL_03638 5.9e-233 S COG0457 FOG TPR repeat
NPPOIMGL_03639 2.2e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NPPOIMGL_03640 6.4e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NPPOIMGL_03641 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NPPOIMGL_03642 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NPPOIMGL_03643 1.3e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NPPOIMGL_03644 3e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NPPOIMGL_03645 1.1e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NPPOIMGL_03646 2.3e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NPPOIMGL_03647 2.9e-96 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NPPOIMGL_03648 8.8e-154 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NPPOIMGL_03649 3.9e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NPPOIMGL_03650 1.9e-138 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NPPOIMGL_03651 5.4e-68 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NPPOIMGL_03652 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NPPOIMGL_03653 1.9e-143 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NPPOIMGL_03654 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NPPOIMGL_03655 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPPOIMGL_03656 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NPPOIMGL_03657 1.3e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NPPOIMGL_03658 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NPPOIMGL_03659 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NPPOIMGL_03660 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPPOIMGL_03661 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NPPOIMGL_03662 1.3e-136 yphF
NPPOIMGL_03663 1.2e-18 yphE S Protein of unknown function (DUF2768)
NPPOIMGL_03664 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NPPOIMGL_03665 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NPPOIMGL_03666 1.6e-28 ypzH
NPPOIMGL_03667 3.3e-161 seaA S YIEGIA protein
NPPOIMGL_03668 3.9e-102 yphA
NPPOIMGL_03669 1e-07 S YpzI-like protein
NPPOIMGL_03670 5.5e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPPOIMGL_03671 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NPPOIMGL_03672 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NPPOIMGL_03673 1.8e-23 S Family of unknown function (DUF5359)
NPPOIMGL_03674 7.9e-85 ypfA M Flagellar protein YcgR
NPPOIMGL_03675 2e-22 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NPPOIMGL_03676 7.1e-231 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NPPOIMGL_03677 9.7e-117 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NPPOIMGL_03679 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
NPPOIMGL_03680 4.7e-177 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NPPOIMGL_03681 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NPPOIMGL_03682 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NPPOIMGL_03683 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
NPPOIMGL_03684 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NPPOIMGL_03685 1.7e-78 ypbE M Lysin motif
NPPOIMGL_03686 5.3e-99 ypbD S metal-dependent membrane protease
NPPOIMGL_03687 7.8e-285 recQ 3.6.4.12 L DNA helicase
NPPOIMGL_03688 5.1e-153 ypbB 5.1.3.1 S protein conserved in bacteria
NPPOIMGL_03689 5.9e-41 ypbB 5.1.3.1 S protein conserved in bacteria
NPPOIMGL_03690 4.7e-41 fer C Ferredoxin
NPPOIMGL_03691 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPPOIMGL_03692 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPPOIMGL_03693 5.2e-47 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NPPOIMGL_03694 5.5e-78 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NPPOIMGL_03695 8e-58 rsiX
NPPOIMGL_03697 5.7e-163 yfiE 1.13.11.2 S glyoxalase
NPPOIMGL_03698 9.8e-65 mhqP S DoxX
NPPOIMGL_03699 1.7e-162 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPPOIMGL_03700 5e-133 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPPOIMGL_03701 2.4e-306 yfiB3 V ABC transporter
NPPOIMGL_03702 0.0 yobO M COG5434 Endopolygalacturonase
NPPOIMGL_03703 0.0 yobO M COG5434 Endopolygalacturonase
NPPOIMGL_03704 1.4e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPPOIMGL_03705 2.7e-140 glvR K Helix-turn-helix domain, rpiR family
NPPOIMGL_03706 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NPPOIMGL_03707 2.6e-44 yfjA S Belongs to the WXG100 family
NPPOIMGL_03708 2e-190 yfjB
NPPOIMGL_03709 1.5e-143 yfjC
NPPOIMGL_03710 1.8e-101 yfjD S Family of unknown function (DUF5381)
NPPOIMGL_03711 6.5e-80 S Family of unknown function (DUF5381)
NPPOIMGL_03712 4e-56 yfjF S UPF0060 membrane protein
NPPOIMGL_03713 1.3e-24 sspH S Belongs to the SspH family
NPPOIMGL_03714 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NPPOIMGL_03715 2.8e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPPOIMGL_03716 1.7e-124 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPPOIMGL_03717 2e-33 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPPOIMGL_03718 1.2e-43 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPPOIMGL_03719 2.2e-145 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPPOIMGL_03720 2.5e-35 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPPOIMGL_03721 6.5e-17 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPPOIMGL_03722 5.5e-186 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPPOIMGL_03723 9.9e-161 ycxC EG EamA-like transporter family
NPPOIMGL_03724 4.7e-249 ycxD K GntR family transcriptional regulator
NPPOIMGL_03725 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NPPOIMGL_03726 9.7e-115 yczE S membrane
NPPOIMGL_03727 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NPPOIMGL_03728 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NPPOIMGL_03729 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NPPOIMGL_03730 1.9e-161 bsdA K LysR substrate binding domain
NPPOIMGL_03731 3.2e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NPPOIMGL_03732 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NPPOIMGL_03733 4e-39 bsdD 4.1.1.61 S response to toxic substance
NPPOIMGL_03734 1.5e-80 yclD
NPPOIMGL_03735 8.9e-107 yclE 3.4.11.5 S Alpha beta hydrolase
NPPOIMGL_03736 2.2e-39 yclE 3.4.11.5 S Alpha beta hydrolase
NPPOIMGL_03737 1.5e-267 dtpT E amino acid peptide transporter
NPPOIMGL_03738 1.2e-292 yclG M Pectate lyase superfamily protein
NPPOIMGL_03740 7.5e-281 gerKA EG Spore germination protein
NPPOIMGL_03741 1.6e-230 gerKC S spore germination
NPPOIMGL_03742 3e-196 gerKB F Spore germination protein
NPPOIMGL_03743 7.3e-121 yclH P ABC transporter
NPPOIMGL_03744 4.3e-141 yclI V ABC transporter (permease) YclI
NPPOIMGL_03745 2.1e-50 yclI V ABC transporter (permease) YclI
NPPOIMGL_03746 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_03747 1.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NPPOIMGL_03748 1.6e-80 S aspartate phosphatase
NPPOIMGL_03751 1.5e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPPOIMGL_03752 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_03753 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_03754 2.4e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NPPOIMGL_03755 5.5e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NPPOIMGL_03756 3.2e-251 ycnB EGP Major facilitator Superfamily
NPPOIMGL_03757 6.5e-154 ycnC K Transcriptional regulator
NPPOIMGL_03758 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NPPOIMGL_03759 1.6e-45 ycnE S Monooxygenase
NPPOIMGL_03760 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NPPOIMGL_03761 3.9e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPPOIMGL_03762 9.1e-236 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NPPOIMGL_03763 2e-256 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPPOIMGL_03764 6.1e-149 glcU U Glucose uptake
NPPOIMGL_03765 6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_03766 1.4e-99 ycnI S protein conserved in bacteria
NPPOIMGL_03767 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NPPOIMGL_03768 3e-100 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NPPOIMGL_03769 3.7e-31
NPPOIMGL_03770 2.2e-26
NPPOIMGL_03771 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NPPOIMGL_03772 3e-87 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPPOIMGL_03773 8.4e-09 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPPOIMGL_03774 2.2e-63 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NPPOIMGL_03775 3.6e-59 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NPPOIMGL_03776 7.3e-155 yycI S protein conserved in bacteria
NPPOIMGL_03777 1.1e-62 yycH S protein conserved in bacteria
NPPOIMGL_03778 7.8e-62 yycH S protein conserved in bacteria
NPPOIMGL_03779 5.1e-96 yycH S protein conserved in bacteria
NPPOIMGL_03780 3.9e-40 vicK 2.7.13.3 T Histidine kinase
NPPOIMGL_03781 2.1e-13 yycH S protein conserved in bacteria
NPPOIMGL_03782 0.0 vicK 2.7.13.3 T Histidine kinase
NPPOIMGL_03783 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_03788 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPPOIMGL_03789 8.7e-65 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPPOIMGL_03790 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NPPOIMGL_03791 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NPPOIMGL_03793 1.9e-15 yycC K YycC-like protein
NPPOIMGL_03794 2.3e-193 yeaN P COG2807 Cyanate permease
NPPOIMGL_03795 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPPOIMGL_03796 4.9e-73 rplI J binds to the 23S rRNA
NPPOIMGL_03797 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NPPOIMGL_03798 1.1e-159 yybS S membrane
NPPOIMGL_03800 3.9e-84 cotF M Spore coat protein
NPPOIMGL_03801 1.5e-67 ydeP3 K Transcriptional regulator
NPPOIMGL_03802 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NPPOIMGL_03803 9.9e-52
NPPOIMGL_03805 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NPPOIMGL_03806 7.4e-111 K TipAS antibiotic-recognition domain
NPPOIMGL_03807 2e-122
NPPOIMGL_03808 2.3e-66 yybH S SnoaL-like domain
NPPOIMGL_03809 1.6e-122 yybG S Pentapeptide repeat-containing protein
NPPOIMGL_03810 2.3e-218 ynfM EGP Major facilitator Superfamily
NPPOIMGL_03811 4e-164 yybE K Transcriptional regulator
NPPOIMGL_03812 7.7e-79 yjcF S Acetyltransferase (GNAT) domain
NPPOIMGL_03813 7.3e-75 yybC
NPPOIMGL_03814 1.2e-71 S Metallo-beta-lactamase superfamily
NPPOIMGL_03815 5.6e-77 yybA 2.3.1.57 K transcriptional
NPPOIMGL_03816 5e-70 yjcF S Acetyltransferase (GNAT) domain
NPPOIMGL_03817 1.2e-68 yyaS S Membrane
NPPOIMGL_03818 4.9e-93 yyaR K Acetyltransferase (GNAT) domain
NPPOIMGL_03819 1.4e-58 yyaQ S YjbR
NPPOIMGL_03822 2.7e-280 gerAA EG Spore germination protein
NPPOIMGL_03823 3.8e-196 gerAB U Spore germination
NPPOIMGL_03824 6.3e-216 gerLC S Spore germination protein
NPPOIMGL_03825 2e-149 yndG S DoxX-like family
NPPOIMGL_03826 1.6e-112 yndH S Domain of unknown function (DUF4166)
NPPOIMGL_03827 8.3e-32 yndJ S YndJ-like protein
NPPOIMGL_03828 3.6e-260 yndJ S YndJ-like protein
NPPOIMGL_03830 8.1e-137 yndL S Replication protein
NPPOIMGL_03831 1.2e-88 yndM S Protein of unknown function (DUF2512)
NPPOIMGL_03832 4.3e-20 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NPPOIMGL_03833 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPPOIMGL_03834 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NPPOIMGL_03835 4.6e-25 yneB L resolvase
NPPOIMGL_03836 5.4e-47 yneB L resolvase
NPPOIMGL_03837 4.8e-32 ynzC S UPF0291 protein
NPPOIMGL_03838 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NPPOIMGL_03839 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NPPOIMGL_03840 1.8e-28 yneF S UPF0154 protein
NPPOIMGL_03841 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NPPOIMGL_03842 1.2e-126 ccdA O cytochrome c biogenesis protein
NPPOIMGL_03843 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NPPOIMGL_03844 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NPPOIMGL_03845 4.2e-74 yneK S Protein of unknown function (DUF2621)
NPPOIMGL_03846 1.2e-64 hspX O Spore coat protein
NPPOIMGL_03847 3.9e-19 sspP S Belongs to the SspP family
NPPOIMGL_03848 2.2e-14 sspO S Belongs to the SspO family
NPPOIMGL_03849 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NPPOIMGL_03850 6.8e-82 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NPPOIMGL_03852 3.1e-08 sspN S Small acid-soluble spore protein N family
NPPOIMGL_03853 8.6e-35 tlp S Belongs to the Tlp family
NPPOIMGL_03854 1.2e-73 yneP S Thioesterase-like superfamily
NPPOIMGL_03855 2.2e-53 yneQ
NPPOIMGL_03856 4.1e-49 yneR S Belongs to the HesB IscA family
NPPOIMGL_03857 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPPOIMGL_03858 6.6e-69 yccU S CoA-binding protein
NPPOIMGL_03859 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPPOIMGL_03860 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPPOIMGL_03861 2.3e-12
NPPOIMGL_03862 3.9e-57 ynfC
NPPOIMGL_03863 4.3e-99 agcS E Sodium alanine symporter
NPPOIMGL_03864 8.9e-162 agcS E Sodium alanine symporter
NPPOIMGL_03865 7.6e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NPPOIMGL_03867 1.8e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NPPOIMGL_03868 1.9e-121 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NPPOIMGL_03869 1.4e-67 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NPPOIMGL_03870 1.7e-102 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NPPOIMGL_03871 2.5e-107 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NPPOIMGL_03872 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPPOIMGL_03873 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPPOIMGL_03874 1.2e-30 csbA S protein conserved in bacteria
NPPOIMGL_03875 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NPPOIMGL_03876 1e-99 yvkB K Transcriptional regulator
NPPOIMGL_03877 4.3e-226 yvkA EGP Major facilitator Superfamily
NPPOIMGL_03878 5.4e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPPOIMGL_03879 1.8e-72 swrA S Swarming motility protein
NPPOIMGL_03880 4.5e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NPPOIMGL_03881 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NPPOIMGL_03882 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NPPOIMGL_03883 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
NPPOIMGL_03884 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NPPOIMGL_03885 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPPOIMGL_03886 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPPOIMGL_03887 4.2e-86 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPPOIMGL_03888 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPPOIMGL_03889 1.8e-65
NPPOIMGL_03890 6.5e-09 fliT S bacterial-type flagellum organization
NPPOIMGL_03891 6.5e-69 fliS N flagellar protein FliS
NPPOIMGL_03892 1.2e-110 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NPPOIMGL_03893 8.1e-213 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPPOIMGL_03894 7.6e-156 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NPPOIMGL_03895 1e-11
NPPOIMGL_03896 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NPPOIMGL_03897 7.7e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPPOIMGL_03898 2.8e-93 M Glycosyltransferase like family 2
NPPOIMGL_03899 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NPPOIMGL_03900 1.7e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPPOIMGL_03901 4e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NPPOIMGL_03902 3.9e-218 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPPOIMGL_03903 6.9e-30 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPPOIMGL_03904 6.3e-263 tuaE M Teichuronic acid biosynthesis protein
NPPOIMGL_03905 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
NPPOIMGL_03906 6.2e-145 tuaG GT2 M Glycosyltransferase like family 2
NPPOIMGL_03907 3.6e-169 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NPPOIMGL_03908 4.5e-46 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NPPOIMGL_03909 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NPPOIMGL_03910 5.6e-163 yvhJ K Transcriptional regulator
NPPOIMGL_03912 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NPPOIMGL_03913 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NPPOIMGL_03914 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPPOIMGL_03915 1.7e-137 degV S protein conserved in bacteria
NPPOIMGL_03916 1.2e-217 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NPPOIMGL_03917 3.7e-45 comFB S Late competence development protein ComFB
NPPOIMGL_03918 1.4e-125 comFC S Phosphoribosyl transferase domain
NPPOIMGL_03919 6.4e-73 yvyF S flagellar protein
NPPOIMGL_03920 1.8e-38 flgM KNU Negative regulator of flagellin synthesis
NPPOIMGL_03921 4.1e-78 flgN NOU FlgN protein
NPPOIMGL_03922 2.7e-264 flgK N flagellar hook-associated protein
NPPOIMGL_03923 7.8e-155 flgL N Belongs to the bacterial flagellin family
NPPOIMGL_03924 3.7e-49 yviE
NPPOIMGL_03925 4.3e-57 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NPPOIMGL_03926 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NPPOIMGL_03927 9e-81 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NPPOIMGL_03928 1.2e-58 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NPPOIMGL_03929 5.8e-77 ykzC S Acetyltransferase (GNAT) family
NPPOIMGL_03930 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
NPPOIMGL_03931 7.1e-26 ykzI
NPPOIMGL_03932 2.1e-117 yktB S Belongs to the UPF0637 family
NPPOIMGL_03933 5.9e-42 yktA S Belongs to the UPF0223 family
NPPOIMGL_03934 2.2e-276 speA 4.1.1.19 E Arginine
NPPOIMGL_03935 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NPPOIMGL_03936 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPPOIMGL_03937 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPPOIMGL_03938 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPPOIMGL_03939 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPPOIMGL_03940 8.5e-114 recN L Putative cell-wall binding lipoprotein
NPPOIMGL_03942 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPPOIMGL_03943 5.5e-147 ykrA S hydrolases of the HAD superfamily
NPPOIMGL_03944 8.2e-31 ykzG S Belongs to the UPF0356 family
NPPOIMGL_03945 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPPOIMGL_03946 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NPPOIMGL_03947 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NPPOIMGL_03948 6.6e-136 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NPPOIMGL_03949 1e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NPPOIMGL_03950 1.5e-43 abrB K of stationary sporulation gene expression
NPPOIMGL_03951 1.7e-182 mreB D Rod-share determining protein MreBH
NPPOIMGL_03952 1.1e-12 S Uncharacterized protein YkpC
NPPOIMGL_03953 5.9e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NPPOIMGL_03954 6.1e-120 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NPPOIMGL_03955 1.6e-27 S Protein of unknown function (DUF2892)
NPPOIMGL_03956 0.0 yerA 3.5.4.2 F adenine deaminase
NPPOIMGL_03957 3.7e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
NPPOIMGL_03958 4.8e-51 yerC S protein conserved in bacteria
NPPOIMGL_03959 3.7e-268 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NPPOIMGL_03962 1.8e-117 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NPPOIMGL_03963 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NPPOIMGL_03964 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPPOIMGL_03965 3e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
NPPOIMGL_03966 1e-195 yerI S homoserine kinase type II (protein kinase fold)
NPPOIMGL_03967 1.6e-123 sapB S MgtC SapB transporter
NPPOIMGL_03968 7.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPPOIMGL_03969 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPPOIMGL_03970 1.7e-160 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPPOIMGL_03971 1.1e-115 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPPOIMGL_03972 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPPOIMGL_03973 3e-141 yerO K Transcriptional regulator
NPPOIMGL_03974 2.4e-108 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NPPOIMGL_03975 6.7e-80 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NPPOIMGL_03976 4.8e-90 oxdC 4.1.1.2 G Oxalate decarboxylase
NPPOIMGL_03979 1.5e-32 yoqW S Belongs to the SOS response-associated peptidase family
NPPOIMGL_03980 3.2e-132 yoqW S Belongs to the SOS response-associated peptidase family
NPPOIMGL_03981 6.8e-195 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NPPOIMGL_03982 5.2e-111 yoaK S Membrane
NPPOIMGL_03983 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NPPOIMGL_03984 2.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NPPOIMGL_03985 2.7e-177 mcpU NT methyl-accepting chemotaxis protein
NPPOIMGL_03986 8.2e-37 S Protein of unknown function (DUF4025)
NPPOIMGL_03987 2.6e-13
NPPOIMGL_03988 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
NPPOIMGL_03989 1.1e-33 yoaF
NPPOIMGL_03990 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NPPOIMGL_03991 1.3e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPPOIMGL_03992 1.3e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NPPOIMGL_03993 3.4e-233 yoaB EGP Major facilitator Superfamily
NPPOIMGL_03994 3.8e-66 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPPOIMGL_03995 9.8e-13 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NPPOIMGL_03996 1.1e-133 yoxB
NPPOIMGL_03997 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
NPPOIMGL_03998 7.2e-116 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_03999 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NPPOIMGL_04000 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPPOIMGL_04001 1.4e-72 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPPOIMGL_04002 9.7e-121 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NPPOIMGL_04003 7.8e-155 gltC K Transcriptional regulator
NPPOIMGL_04004 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NPPOIMGL_04005 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NPPOIMGL_04006 3.7e-179 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NPPOIMGL_04007 3.4e-130 gltR1 K Transcriptional regulator
NPPOIMGL_04008 1.2e-55 gltR1 K Transcriptional regulator
NPPOIMGL_04009 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NPPOIMGL_04010 3e-34 yoeD G Helix-turn-helix domain
NPPOIMGL_04011 2.2e-96 L Integrase
NPPOIMGL_04013 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NPPOIMGL_04014 8.7e-246 yoeA V MATE efflux family protein
NPPOIMGL_04015 9.4e-130 yoxA 5.1.3.3 G Aldose 1-epimerase
NPPOIMGL_04016 6.9e-80 yoxA 5.1.3.3 G Aldose 1-epimerase
NPPOIMGL_04017 7.5e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NPPOIMGL_04018 2.1e-22 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_04019 7.3e-50 S YolD-like protein
NPPOIMGL_04022 2.5e-170
NPPOIMGL_04024 8.1e-38 S Domain of unknown function (DUF4062)
NPPOIMGL_04026 1.4e-97 S aspartate phosphatase
NPPOIMGL_04027 5.8e-40 S Protein of unknown function, DUF600
NPPOIMGL_04028 7.5e-142 L nucleic acid phosphodiester bond hydrolysis
NPPOIMGL_04029 4.5e-34 S DnaA N-terminal domain
NPPOIMGL_04031 2e-22 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NPPOIMGL_04032 2.9e-82 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NPPOIMGL_04039 7.5e-61 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPPOIMGL_04040 2.4e-14
NPPOIMGL_04043 0.0 5.99.1.2 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NPPOIMGL_04044 9.4e-91 L DNA restriction-modification system
NPPOIMGL_04050 6.6e-105 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPPOIMGL_04053 3.3e-214 pcrA 3.6.4.12 L UvrD/REP helicase N-terminal domain
NPPOIMGL_04055 9.4e-133 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
NPPOIMGL_04057 2.2e-22
NPPOIMGL_04061 4e-25 sspB S spore protein
NPPOIMGL_04063 3.6e-55 comGE
NPPOIMGL_04064 1e-42 gspH NU protein transport across the cell outer membrane
NPPOIMGL_04065 3e-47 comGC U Required for transformation and DNA binding
NPPOIMGL_04066 6.2e-172 comGB NU COG1459 Type II secretory pathway, component PulF
NPPOIMGL_04067 5e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NPPOIMGL_04068 7.2e-175 corA P Mg2 transporter protein
NPPOIMGL_04069 7.5e-105 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NPPOIMGL_04070 1.1e-150 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NPPOIMGL_04071 8.6e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NPPOIMGL_04073 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NPPOIMGL_04074 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NPPOIMGL_04075 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NPPOIMGL_04076 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NPPOIMGL_04077 6.9e-50 yqgV S Thiamine-binding protein
NPPOIMGL_04078 1.5e-197 yqgU
NPPOIMGL_04079 1.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NPPOIMGL_04080 3.2e-264 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NPPOIMGL_04081 9.8e-84 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NPPOIMGL_04082 5.2e-181 glcK 2.7.1.2 G Glucokinase
NPPOIMGL_04083 1.9e-29 yqgQ S Protein conserved in bacteria
NPPOIMGL_04084 4.6e-254 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NPPOIMGL_04085 2.5e-09 yqgO
NPPOIMGL_04086 2.1e-68 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPPOIMGL_04087 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPPOIMGL_04088 8.5e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NPPOIMGL_04090 9.2e-51 yqzD
NPPOIMGL_04091 4.7e-63 yqzC S YceG-like family
NPPOIMGL_04092 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPPOIMGL_04093 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPPOIMGL_04094 4.4e-158 pstA P Phosphate transport system permease
NPPOIMGL_04095 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NPPOIMGL_04096 5.4e-142 pstS P Phosphate
NPPOIMGL_04097 1.8e-61 pbpA 3.4.16.4 M penicillin-binding protein
NPPOIMGL_04098 4.2e-22 pbpA 3.4.16.4 M penicillin-binding protein
NPPOIMGL_04099 5.6e-268 pbpA 3.4.16.4 M penicillin-binding protein
NPPOIMGL_04100 2.5e-231 yqgE EGP Major facilitator superfamily
NPPOIMGL_04101 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NPPOIMGL_04102 4e-73 yqgC S protein conserved in bacteria
NPPOIMGL_04103 1.1e-130 yqgB S Protein of unknown function (DUF1189)
NPPOIMGL_04104 5.2e-47 yqfZ M LysM domain
NPPOIMGL_04105 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NPPOIMGL_04106 2.8e-61 yqfX S membrane
NPPOIMGL_04107 7.9e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NPPOIMGL_04108 1.9e-77 zur P Belongs to the Fur family
NPPOIMGL_04109 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NPPOIMGL_04110 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NPPOIMGL_04111 1.1e-164 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NPPOIMGL_04112 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPPOIMGL_04114 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NPPOIMGL_04115 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPPOIMGL_04116 1.6e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
NPPOIMGL_04117 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NPPOIMGL_04118 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPPOIMGL_04119 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPPOIMGL_04120 1.7e-87 yaiI S Belongs to the UPF0178 family
NPPOIMGL_04121 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPPOIMGL_04122 4.5e-112 ccpN K CBS domain
NPPOIMGL_04123 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NPPOIMGL_04124 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NPPOIMGL_04125 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
NPPOIMGL_04126 8.4e-19 S YqzL-like protein
NPPOIMGL_04127 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPPOIMGL_04128 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NPPOIMGL_04129 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NPPOIMGL_04130 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPPOIMGL_04131 2.5e-155 yqfF S membrane-associated HD superfamily hydrolase
NPPOIMGL_04132 1.3e-77 yqfF S membrane-associated HD superfamily hydrolase
NPPOIMGL_04133 1.6e-142 yqfF S membrane-associated HD superfamily hydrolase
NPPOIMGL_04135 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NPPOIMGL_04136 1.9e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NPPOIMGL_04137 2.7e-45 yqfC S sporulation protein YqfC
NPPOIMGL_04138 1.9e-23 yqfB
NPPOIMGL_04139 4.3e-122 yqfA S UPF0365 protein
NPPOIMGL_04140 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NPPOIMGL_04141 2.5e-61 yqeY S Yqey-like protein
NPPOIMGL_04142 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NPPOIMGL_04143 3.8e-138 yqeW P COG1283 Na phosphate symporter
NPPOIMGL_04144 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NPPOIMGL_04145 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NPPOIMGL_04146 5.4e-175 prmA J Methylates ribosomal protein L11
NPPOIMGL_04147 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPPOIMGL_04148 5.8e-309 dnaK O Heat shock 70 kDa protein
NPPOIMGL_04149 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPPOIMGL_04150 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPPOIMGL_04151 5.9e-191 hemN H Involved in the biosynthesis of porphyrin-containing compound
NPPOIMGL_04152 2.3e-32 hemN H Involved in the biosynthesis of porphyrin-containing compound
NPPOIMGL_04153 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPPOIMGL_04154 4.7e-52 yqxA S Protein of unknown function (DUF3679)
NPPOIMGL_04155 1.5e-222 spoIIP M stage II sporulation protein P
NPPOIMGL_04156 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NPPOIMGL_04157 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NPPOIMGL_04158 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NPPOIMGL_04159 4.1e-15 S YqzM-like protein
NPPOIMGL_04160 0.0 comEC S Competence protein ComEC
NPPOIMGL_04161 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NPPOIMGL_04162 5.5e-100 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NPPOIMGL_04163 7.1e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NPPOIMGL_04164 2.6e-116 yqeM Q Methyltransferase
NPPOIMGL_04165 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPPOIMGL_04166 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NPPOIMGL_04167 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPPOIMGL_04168 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NPPOIMGL_04169 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NPPOIMGL_04170 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NPPOIMGL_04171 5.3e-95 yqeG S hydrolase of the HAD superfamily
NPPOIMGL_04173 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NPPOIMGL_04174 1.8e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPPOIMGL_04175 3.5e-12 yqeD S SNARE associated Golgi protein
NPPOIMGL_04176 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPPOIMGL_04177 5.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPPOIMGL_04178 9e-37 ykuS S Belongs to the UPF0180 family
NPPOIMGL_04179 2.2e-67 ykuT M Mechanosensitive ion channel
NPPOIMGL_04180 1.4e-26 ykuT M Mechanosensitive ion channel
NPPOIMGL_04181 1.7e-73 ykuU O Alkyl hydroperoxide reductase
NPPOIMGL_04182 4e-25 ykuU O Alkyl hydroperoxide reductase
NPPOIMGL_04183 7e-80 ykuV CO thiol-disulfide
NPPOIMGL_04184 5.8e-95 rok K Repressor of ComK
NPPOIMGL_04185 1.3e-144 yknT
NPPOIMGL_04186 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NPPOIMGL_04187 1.3e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NPPOIMGL_04188 8.1e-246 moeA 2.10.1.1 H molybdopterin
NPPOIMGL_04189 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NPPOIMGL_04190 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NPPOIMGL_04191 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NPPOIMGL_04192 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPPOIMGL_04193 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NPPOIMGL_04194 2.5e-116 yknW S Yip1 domain
NPPOIMGL_04195 9.5e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NPPOIMGL_04196 9.4e-124 macB V ABC transporter, ATP-binding protein
NPPOIMGL_04197 1.2e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NPPOIMGL_04198 3.1e-136 fruR K Transcriptional regulator
NPPOIMGL_04199 1.2e-166 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NPPOIMGL_04200 1.2e-309 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NPPOIMGL_04201 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NPPOIMGL_04202 8.1e-39 ykoA
NPPOIMGL_04203 2.7e-266 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPPOIMGL_04204 8.6e-44 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NPPOIMGL_04205 3.7e-70 pcaC 4.1.1.44 S conserved protein, contains double-stranded beta-helix domain
NPPOIMGL_04206 2.8e-46 yraB K helix_turn_helix, mercury resistance
NPPOIMGL_04207 1.8e-13 rmeD K MerR family transcriptional regulator
NPPOIMGL_04208 3.2e-17 rmeD K MerR family transcriptional regulator
NPPOIMGL_04210 2.3e-114 K Transcriptional regulator
NPPOIMGL_04211 5.3e-165 yajO C Aldo/keto reductase family
NPPOIMGL_04212 8e-13 ptsH G phosphocarrier protein HPr
NPPOIMGL_04213 1.1e-47 yraD M Spore coat protein
NPPOIMGL_04214 7.5e-26 yraE
NPPOIMGL_04215 6.9e-62 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPPOIMGL_04216 1.1e-112 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPPOIMGL_04217 2.3e-14 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPPOIMGL_04218 6.4e-63 yraF M Spore coat protein
NPPOIMGL_04219 1.5e-36 yraG
NPPOIMGL_04220 2.1e-64 E Glyoxalase-like domain
NPPOIMGL_04221 5.4e-61 T sh3 domain protein
NPPOIMGL_04222 1.3e-40 T sh3 domain protein
NPPOIMGL_04223 1.8e-78 S Alpha beta hydrolase
NPPOIMGL_04224 1.1e-98 S Alpha beta hydrolase
NPPOIMGL_04225 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPPOIMGL_04226 8.5e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NPPOIMGL_04227 1.9e-186 yrpG C Aldo/keto reductase family
NPPOIMGL_04228 9.1e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_04229 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NPPOIMGL_04231 2.9e-26 epsA I Passenger-associated-transport-repeat
NPPOIMGL_04232 2.1e-49 yjbR S YjbR
NPPOIMGL_04233 7.2e-118 bmrR K helix_turn_helix, mercury resistance
NPPOIMGL_04234 1.9e-98 flr S Flavin reductase like domain
NPPOIMGL_04235 1.6e-123 yrpD S Domain of unknown function, YrpD
NPPOIMGL_04236 3.8e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NPPOIMGL_04237 5.4e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NPPOIMGL_04238 2.2e-13 aadK G Streptomycin adenylyltransferase
NPPOIMGL_04239 1.8e-164 aadK G Streptomycin adenylyltransferase
NPPOIMGL_04240 3.2e-89 yrdA S DinB family
NPPOIMGL_04241 4e-55 S Protein of unknown function (DUF2568)
NPPOIMGL_04242 5.7e-33 yvkN
NPPOIMGL_04243 8e-49 yvlA
NPPOIMGL_04244 2.4e-166 yvlB S Putative adhesin
NPPOIMGL_04245 2.6e-26 pspB KT PspC domain
NPPOIMGL_04246 1.2e-50 yvlD S Membrane
NPPOIMGL_04247 8.7e-101 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NPPOIMGL_04248 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NPPOIMGL_04249 6e-123 yvoA K transcriptional
NPPOIMGL_04250 8.2e-124 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPPOIMGL_04251 2.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPPOIMGL_04252 1.9e-66 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPPOIMGL_04253 2.7e-63 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPPOIMGL_04254 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPPOIMGL_04255 4.9e-160 yvoD P COG0370 Fe2 transport system protein B
NPPOIMGL_04256 4.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NPPOIMGL_04257 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NPPOIMGL_04258 5.8e-33 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NPPOIMGL_04259 1.2e-71 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NPPOIMGL_04260 1e-139 yvpB NU protein conserved in bacteria
NPPOIMGL_04261 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NPPOIMGL_04262 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NPPOIMGL_04263 9.9e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NPPOIMGL_04264 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NPPOIMGL_04265 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NPPOIMGL_04266 1.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NPPOIMGL_04267 3.3e-123 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NPPOIMGL_04268 2.2e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NPPOIMGL_04269 4e-77
NPPOIMGL_04270 5.3e-269
NPPOIMGL_04271 1.1e-62
NPPOIMGL_04272 1.5e-22 K Cro/C1-type HTH DNA-binding domain
NPPOIMGL_04273 1.3e-210 hsdM 2.1.1.72 V type I restriction-modification system
NPPOIMGL_04274 2.7e-91 2.1.1.72, 3.1.21.3 L Type I restriction modification DNA specificity domain
NPPOIMGL_04275 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NPPOIMGL_04276 1.9e-27 XK26_06125 S Transcriptional Coactivator p15 (PC4)
NPPOIMGL_04277 1e-19
NPPOIMGL_04278 0.0 E Zn peptidase
NPPOIMGL_04280 1.2e-31
NPPOIMGL_04281 1.1e-206 L Protein of unknown function (DUF2800)
NPPOIMGL_04282 1e-88 S Protein of unknown function (DUF2815)
NPPOIMGL_04283 0.0 2.7.7.7 L DNA polymerase A domain
NPPOIMGL_04284 4.5e-146 K BRO family, N-terminal domain
NPPOIMGL_04286 0.0 L Virulence-associated protein E
NPPOIMGL_04287 7e-38 S VRR_NUC
NPPOIMGL_04288 7.3e-68 KL SNF2 family N-terminal domain
NPPOIMGL_04289 3.8e-34 S Peptidase propeptide and YPEB domain
NPPOIMGL_04290 1.2e-73 S Peptidase propeptide and YPEB domain
NPPOIMGL_04291 3.4e-94 K PFAM response regulator receiver
NPPOIMGL_04292 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
NPPOIMGL_04293 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NPPOIMGL_04294 1.4e-198 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NPPOIMGL_04295 3.7e-41 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NPPOIMGL_04296 5.7e-209 rocE E amino acid
NPPOIMGL_04297 4.4e-10 rocE E amino acid
NPPOIMGL_04298 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NPPOIMGL_04300 2.3e-183 S aspartate phosphatase
NPPOIMGL_04301 7.5e-53 yycN 2.3.1.128 K Acetyltransferase
NPPOIMGL_04302 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NPPOIMGL_04303 2.7e-30 yycP
NPPOIMGL_04304 2.8e-196 yycP
NPPOIMGL_04305 8.2e-30 yycQ S Protein of unknown function (DUF2651)
NPPOIMGL_04308 3.2e-54 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPPOIMGL_04309 1.1e-99 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NPPOIMGL_04310 8.8e-31
NPPOIMGL_04311 7.1e-30
NPPOIMGL_04312 3.6e-09 S YyzF-like protein
NPPOIMGL_04313 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPPOIMGL_04315 3.2e-116 V PFAM AAA domain (dynein-related subfamily)
NPPOIMGL_04316 2.7e-133
NPPOIMGL_04321 7.5e-87
NPPOIMGL_04322 9.9e-74 K BRO family, N-terminal domain
NPPOIMGL_04323 2e-33
NPPOIMGL_04324 2.2e-13 K Helix-turn-helix domain
NPPOIMGL_04325 1.1e-16 xre K Helix-turn-helix XRE-family like proteins
NPPOIMGL_04327 1.1e-47
NPPOIMGL_04328 1.8e-27 S Protein of unknown function (DUF4064)
NPPOIMGL_04329 1.4e-47 xkdA E IrrE N-terminal-like domain
NPPOIMGL_04330 4.4e-145 L Belongs to the 'phage' integrase family
NPPOIMGL_04331 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPPOIMGL_04332 1.7e-11 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPPOIMGL_04333 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPPOIMGL_04334 7.9e-129 ydiL S CAAX protease self-immunity
NPPOIMGL_04335 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NPPOIMGL_04336 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NPPOIMGL_04337 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NPPOIMGL_04338 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPPOIMGL_04339 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NPPOIMGL_04340 3.5e-203 ydiF S ABC transporter
NPPOIMGL_04341 4e-101 ydiF S ABC transporter
NPPOIMGL_04342 5.2e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPPOIMGL_04343 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NPPOIMGL_04344 4.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NPPOIMGL_04345 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NPPOIMGL_04346 1.8e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NPPOIMGL_04348 7.8e-08
NPPOIMGL_04349 1.2e-13 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NPPOIMGL_04350 1.7e-162 rhaS5 K AraC-like ligand binding domain
NPPOIMGL_04351 2.2e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NPPOIMGL_04352 1.2e-163 ydeE K AraC family transcriptional regulator
NPPOIMGL_04353 5.2e-75 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPPOIMGL_04354 4e-153 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPPOIMGL_04355 1.5e-20 ydeG EGP Major facilitator superfamily
NPPOIMGL_04356 6.7e-170 ydeG EGP Major facilitator superfamily
NPPOIMGL_04357 2.7e-45 ydeH
NPPOIMGL_04358 1.3e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NPPOIMGL_04359 3.8e-32
NPPOIMGL_04360 1e-106
NPPOIMGL_04361 3.7e-15 ptsH G PTS HPr component phosphorylation site
NPPOIMGL_04362 8.8e-85 K Transcriptional regulator C-terminal region
NPPOIMGL_04363 1.8e-153 ydeK EG -transporter
NPPOIMGL_04364 2.6e-174 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPPOIMGL_04365 3e-48 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NPPOIMGL_04366 1.3e-72 maoC I N-terminal half of MaoC dehydratase
NPPOIMGL_04367 1.3e-12 ydeN S Serine hydrolase
NPPOIMGL_04368 4.5e-32 ydeN S Serine hydrolase
NPPOIMGL_04369 3.5e-49 K HxlR-like helix-turn-helix
NPPOIMGL_04370 8.7e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NPPOIMGL_04371 1.8e-68 ydeP K Transcriptional regulator
NPPOIMGL_04372 1.1e-109 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
NPPOIMGL_04373 1.2e-192 ydeR EGP Major facilitator Superfamily
NPPOIMGL_04374 3.2e-104 ydeS K Transcriptional regulator
NPPOIMGL_04375 1e-56 L Reverse transcriptase (RNA-dependent DNA polymerase)
NPPOIMGL_04376 3.3e-10 L reverse transcriptase
NPPOIMGL_04377 1.3e-87
NPPOIMGL_04378 2.6e-63
NPPOIMGL_04380 0.0 L helicase
NPPOIMGL_04381 2.3e-288 L helicase
NPPOIMGL_04383 2.8e-40
NPPOIMGL_04384 5.1e-25 S Ankyrin repeat
NPPOIMGL_04387 3.7e-10 S T5orf172
NPPOIMGL_04388 1.2e-98
NPPOIMGL_04390 3.6e-84 L Psort location Cytoplasmic, score
NPPOIMGL_04391 6.3e-61 yxaC M effector of murein hydrolase
NPPOIMGL_04392 4.9e-33 yxaC M effector of murein hydrolase
NPPOIMGL_04393 5.2e-50 S LrgA family
NPPOIMGL_04394 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NPPOIMGL_04395 1.6e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_04396 4.6e-100 yxaF K Transcriptional regulator
NPPOIMGL_04397 6.4e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
NPPOIMGL_04398 3.6e-222 P Protein of unknown function (DUF418)
NPPOIMGL_04399 1.4e-75 yxaI S membrane protein domain
NPPOIMGL_04400 1.1e-63 S Family of unknown function (DUF5391)
NPPOIMGL_04401 8.3e-91 S PQQ-like domain
NPPOIMGL_04402 6.4e-25 yxaI S membrane protein domain
NPPOIMGL_04403 1.2e-244 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NPPOIMGL_04404 4.5e-208 yxbF K Bacterial regulatory proteins, tetR family
NPPOIMGL_04405 3.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
NPPOIMGL_04407 4.9e-67 htpG O Molecular chaperone. Has ATPase activity
NPPOIMGL_04408 5.7e-220 htpG O Molecular chaperone. Has ATPase activity
NPPOIMGL_04409 4.6e-25 csbC EGP Major facilitator Superfamily
NPPOIMGL_04410 3e-85 csbC EGP Major facilitator Superfamily
NPPOIMGL_04411 8.7e-128 csbC EGP Major facilitator Superfamily
NPPOIMGL_04412 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NPPOIMGL_04414 2.7e-79 iolS C Aldo keto reductase
NPPOIMGL_04415 1.2e-119 iolS C Aldo keto reductase
NPPOIMGL_04416 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NPPOIMGL_04417 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NPPOIMGL_04418 2.1e-61 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NPPOIMGL_04419 7.8e-69 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NPPOIMGL_04420 6.7e-34 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NPPOIMGL_04421 7.9e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NPPOIMGL_04422 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NPPOIMGL_04423 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NPPOIMGL_04424 8.5e-26 iolF EGP Major facilitator Superfamily
NPPOIMGL_04425 2.8e-181 iolF EGP Major facilitator Superfamily
NPPOIMGL_04426 8.3e-189 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NPPOIMGL_04427 6.2e-46 ybbM S transport system, permease component
NPPOIMGL_04428 3.5e-112 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NPPOIMGL_04429 1.7e-31 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NPPOIMGL_04430 8.2e-30
NPPOIMGL_04431 1.1e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NPPOIMGL_04432 1.8e-207 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NPPOIMGL_04434 2.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NPPOIMGL_04435 2e-10 S Domain of unknown function (DUF4352)
NPPOIMGL_04436 3.7e-94 yjgD S Protein of unknown function (DUF1641)
NPPOIMGL_04437 2.4e-71 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NPPOIMGL_04438 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NPPOIMGL_04439 3.8e-102 yjgB S Domain of unknown function (DUF4309)
NPPOIMGL_04440 2.3e-68 T PhoQ Sensor
NPPOIMGL_04441 6.6e-156 yjfC O Predicted Zn-dependent protease (DUF2268)
NPPOIMGL_04442 2.3e-20 yjfB S Putative motility protein
NPPOIMGL_04443 1.8e-81 S Protein of unknown function (DUF2690)
NPPOIMGL_04444 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
NPPOIMGL_04446 7.5e-63 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NPPOIMGL_04447 6.9e-136 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NPPOIMGL_04448 1.5e-50 yjdJ S Domain of unknown function (DUF4306)
NPPOIMGL_04449 3e-44 yjdJ S Domain of unknown function (DUF4306)
NPPOIMGL_04450 2.7e-22 S Domain of unknown function (DUF4177)
NPPOIMGL_04451 2.2e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPPOIMGL_04453 5.9e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NPPOIMGL_04454 3e-45 yjdF S Protein of unknown function (DUF2992)
NPPOIMGL_04455 2.6e-94 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPPOIMGL_04456 2.1e-110 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPPOIMGL_04457 1.2e-246 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NPPOIMGL_04458 2e-48 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NPPOIMGL_04459 1.5e-36 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NPPOIMGL_04460 1.2e-33 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NPPOIMGL_04461 9.7e-56 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NPPOIMGL_04462 0.0 copA 3.6.3.54 P P-type ATPase
NPPOIMGL_04463 2.9e-288 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NPPOIMGL_04464 7.5e-50 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NPPOIMGL_04466 1.6e-104 bdbD O Thioredoxin
NPPOIMGL_04467 3.8e-46 bdbC O Required for disulfide bond formation in some proteins
NPPOIMGL_04468 1.6e-106 yvgT S membrane
NPPOIMGL_04470 1.8e-273 helD 3.6.4.12 L DNA helicase
NPPOIMGL_04471 4.5e-145 helD 3.6.4.12 L DNA helicase
NPPOIMGL_04472 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NPPOIMGL_04473 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NPPOIMGL_04474 1.4e-15 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NPPOIMGL_04476 5.7e-230 yjcE P COG0025 NhaP-type Na H and K H antiporters
NPPOIMGL_04477 7.3e-63 yjcE P COG0025 NhaP-type Na H and K H antiporters
NPPOIMGL_04478 2.4e-73 yvgO
NPPOIMGL_04479 5.9e-157 yvgN S reductase
NPPOIMGL_04480 3.3e-46 modB P COG4149 ABC-type molybdate transport system, permease component
NPPOIMGL_04481 3.2e-81 modB P COG4149 ABC-type molybdate transport system, permease component
NPPOIMGL_04482 3.2e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NPPOIMGL_04483 3.7e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NPPOIMGL_04484 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NPPOIMGL_04485 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NPPOIMGL_04486 6.5e-16 S Small spore protein J (Spore_SspJ)
NPPOIMGL_04487 4.9e-236 yvsH E Arginine ornithine antiporter
NPPOIMGL_04488 1e-176 fhuD P ABC transporter
NPPOIMGL_04489 7.9e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_04490 2.9e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_04491 3.7e-148 fhuC 3.6.3.34 HP ABC transporter
NPPOIMGL_04492 2e-174 M Efflux transporter rnd family, mfp subunit
NPPOIMGL_04493 2.1e-123 macB V ABC transporter, ATP-binding protein
NPPOIMGL_04494 1.2e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NPPOIMGL_04495 1.3e-64 yvrL S Regulatory protein YrvL
NPPOIMGL_04496 2.3e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
NPPOIMGL_04497 2.4e-19 S YvrJ protein family
NPPOIMGL_04498 9.5e-98 yvrI K RNA polymerase
NPPOIMGL_04499 3.6e-22
NPPOIMGL_04500 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_04501 0.0 T PhoQ Sensor
NPPOIMGL_04502 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NPPOIMGL_04503 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_04504 8.7e-82 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NPPOIMGL_04505 2.8e-39 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NPPOIMGL_04506 4.2e-49 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NPPOIMGL_04507 2.7e-162 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPPOIMGL_04508 4.9e-246 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NPPOIMGL_04509 6.1e-100 yvqK 2.5.1.17 S Adenosyltransferase
NPPOIMGL_04510 3.4e-148 yvqJ EGP Major facilitator Superfamily
NPPOIMGL_04511 1.9e-60 yvqJ EGP Major facilitator Superfamily
NPPOIMGL_04512 2.8e-61 liaI S membrane
NPPOIMGL_04513 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NPPOIMGL_04514 6e-128 liaG S Putative adhesin
NPPOIMGL_04515 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NPPOIMGL_04516 1.9e-174 vraS 2.7.13.3 T Histidine kinase
NPPOIMGL_04517 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NPPOIMGL_04518 8.8e-85 gerAC S Spore germination B3/ GerAC like, C-terminal
NPPOIMGL_04519 2.9e-87 gerAC S Spore germination B3/ GerAC like, C-terminal
NPPOIMGL_04520 1.2e-80 gerAB E Spore germination protein
NPPOIMGL_04521 7e-122 gerAB E Spore germination protein
NPPOIMGL_04522 4.3e-110 gerAA EG Spore germination protein
NPPOIMGL_04523 1.6e-124 gerAA EG Spore germination protein
NPPOIMGL_04524 3.9e-24 S Protein of unknown function (DUF3970)
NPPOIMGL_04525 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPPOIMGL_04526 4.3e-158 yuxN K Transcriptional regulator
NPPOIMGL_04527 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NPPOIMGL_04528 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_04529 1.2e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NPPOIMGL_04530 1.2e-79 dps P Ferritin-like domain
NPPOIMGL_04531 4.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_04532 1.2e-300 pepF2 E COG1164 Oligoendopeptidase F
NPPOIMGL_04533 1.9e-66 S YusW-like protein
NPPOIMGL_04534 1e-153 yusV 3.6.3.34 HP ABC transporter
NPPOIMGL_04535 1.5e-46 yusU S Protein of unknown function (DUF2573)
NPPOIMGL_04536 5.7e-158 yusT K LysR substrate binding domain
NPPOIMGL_04537 5.5e-106 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_04538 2.1e-64 yusQ S Tautomerase enzyme
NPPOIMGL_04539 1.2e-291 yusP P Major facilitator superfamily
NPPOIMGL_04540 2e-68 yusO K Iron dependent repressor, N-terminal DNA binding domain
NPPOIMGL_04541 5.4e-53 yusN M Coat F domain
NPPOIMGL_04542 5.1e-40
NPPOIMGL_04543 3.2e-164 fadM E Proline dehydrogenase
NPPOIMGL_04544 8.1e-09 S YuzL-like protein
NPPOIMGL_04545 8.2e-266 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NPPOIMGL_04546 5.6e-77 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NPPOIMGL_04547 1.8e-76 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NPPOIMGL_04548 2.4e-36 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NPPOIMGL_04549 5.2e-78 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NPPOIMGL_04550 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
NPPOIMGL_04551 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NPPOIMGL_04552 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NPPOIMGL_04553 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NPPOIMGL_04554 4.1e-39 yusG S Protein of unknown function (DUF2553)
NPPOIMGL_04555 4.8e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NPPOIMGL_04556 1.2e-54 traF CO Thioredoxin
NPPOIMGL_04557 3.2e-56 yusD S SCP-2 sterol transfer family
NPPOIMGL_04558 5.2e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPPOIMGL_04559 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NPPOIMGL_04560 9.4e-147 metQ P Belongs to the NlpA lipoprotein family
NPPOIMGL_04561 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NPPOIMGL_04562 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NPPOIMGL_04563 1.4e-245 sufD O assembly protein SufD
NPPOIMGL_04564 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPPOIMGL_04565 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NPPOIMGL_04566 3.5e-271 sufB O FeS cluster assembly
NPPOIMGL_04567 1.1e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
NPPOIMGL_04568 1.3e-63 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPPOIMGL_04569 1e-41
NPPOIMGL_04571 1.7e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NPPOIMGL_04574 5.8e-92 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NPPOIMGL_04575 1e-122 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NPPOIMGL_04576 2.3e-98 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NPPOIMGL_04577 4.8e-39 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NPPOIMGL_04578 3.8e-165 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NPPOIMGL_04579 2e-144 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NPPOIMGL_04580 2.9e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NPPOIMGL_04581 1e-171 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NPPOIMGL_04583 4.6e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NPPOIMGL_04584 2.2e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NPPOIMGL_04585 3.5e-168 bsn L Ribonuclease
NPPOIMGL_04586 5.9e-205 msmX P Belongs to the ABC transporter superfamily
NPPOIMGL_04587 2e-66 yurK K UTRA
NPPOIMGL_04588 2.7e-51 yurK K UTRA
NPPOIMGL_04589 1.2e-64 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NPPOIMGL_04590 6.8e-74 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NPPOIMGL_04591 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
NPPOIMGL_04592 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
NPPOIMGL_04593 1.2e-152 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NPPOIMGL_04594 7.2e-47 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NPPOIMGL_04595 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NPPOIMGL_04596 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NPPOIMGL_04597 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NPPOIMGL_04598 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NPPOIMGL_04599 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPPOIMGL_04600 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPPOIMGL_04601 1.1e-206 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPPOIMGL_04602 2.1e-103 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPPOIMGL_04603 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPPOIMGL_04604 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
NPPOIMGL_04605 3.9e-150 yaaH M Glycoside Hydrolase Family
NPPOIMGL_04606 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NPPOIMGL_04607 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NPPOIMGL_04608 1.3e-09
NPPOIMGL_04609 3.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPPOIMGL_04610 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NPPOIMGL_04611 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NPPOIMGL_04612 7.1e-65 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPPOIMGL_04613 1.7e-44 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPPOIMGL_04614 3.6e-129 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPPOIMGL_04615 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NPPOIMGL_04616 1.6e-179 yaaC S YaaC-like Protein
NPPOIMGL_04617 1.7e-91 lysP E amino acid
NPPOIMGL_04618 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NPPOIMGL_04619 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NPPOIMGL_04620 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NPPOIMGL_04621 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NPPOIMGL_04622 2.7e-143 yxxB S Domain of Unknown Function (DUF1206)
NPPOIMGL_04623 6e-107 eutH E Ethanolamine utilisation protein, EutH
NPPOIMGL_04624 4.9e-102 eutH E Ethanolamine utilisation protein, EutH
NPPOIMGL_04625 4.4e-247 yxeQ S MmgE/PrpD family
NPPOIMGL_04626 1.9e-214 yxeP 3.5.1.47 E hydrolase activity
NPPOIMGL_04627 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NPPOIMGL_04628 1.6e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
NPPOIMGL_04629 3.6e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
NPPOIMGL_04630 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPPOIMGL_04631 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPPOIMGL_04632 1.4e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NPPOIMGL_04633 7.6e-149 yidA S hydrolases of the HAD superfamily
NPPOIMGL_04636 1.3e-20 yxeE
NPPOIMGL_04637 9.6e-16 yxeD
NPPOIMGL_04638 8.5e-69
NPPOIMGL_04639 1.1e-175 fhuD P ABC transporter
NPPOIMGL_04640 1.3e-57 yxeA S Protein of unknown function (DUF1093)
NPPOIMGL_04641 4.1e-234 yxdM V ABC transporter (permease)
NPPOIMGL_04642 1.9e-42 yxdM V ABC transporter (permease)
NPPOIMGL_04643 5.2e-66 yxdM V ABC transporter (permease)
NPPOIMGL_04644 5.1e-78 yxdL V ABC transporter, ATP-binding protein
NPPOIMGL_04645 1.2e-71 yxdL V ABC transporter, ATP-binding protein
NPPOIMGL_04646 4e-181 T PhoQ Sensor
NPPOIMGL_04647 1.2e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_04648 5.4e-154 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NPPOIMGL_04649 2.5e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NPPOIMGL_04650 2.6e-70 iolH G Xylose isomerase-like TIM barrel
NPPOIMGL_04651 2.6e-42 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NPPOIMGL_04652 3.3e-253 xynT G MFS/sugar transport protein
NPPOIMGL_04653 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NPPOIMGL_04654 2.3e-212 xylR GK ROK family
NPPOIMGL_04655 2e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NPPOIMGL_04656 1.5e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NPPOIMGL_04657 5.8e-112 yokF 3.1.31.1 L RNA catabolic process
NPPOIMGL_04658 2e-253 iolT EGP Major facilitator Superfamily
NPPOIMGL_04659 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPPOIMGL_04661 1.3e-81 yncE S Protein of unknown function (DUF2691)
NPPOIMGL_04662 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NPPOIMGL_04663 5.2e-15
NPPOIMGL_04664 4.5e-23 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NPPOIMGL_04665 1.7e-112 L DDE domain
NPPOIMGL_04667 8.5e-226 I acetylesterase activity
NPPOIMGL_04668 1.4e-156 EGP Major facilitator Superfamily
NPPOIMGL_04669 1.2e-94 ligK 4.1.3.17 H Aldolase/RraA
NPPOIMGL_04670 2e-116 4.2.1.83 S GlcNAc-PI de-N-acetylase
NPPOIMGL_04671 1.5e-59 MA20_21375 3.5.99.10 J Endoribonuclease L-PSP
NPPOIMGL_04672 2.9e-63 K FCD
NPPOIMGL_04673 2.8e-166 MA20_26520 1.13.11.2 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NPPOIMGL_04674 5.9e-191 benK EGP Major facilitator Superfamily
NPPOIMGL_04675 2.5e-94 smtA 2.1.1.104 S O-methyltransferase
NPPOIMGL_04676 4.6e-35
NPPOIMGL_04677 4e-07 L COG3344 Retron-type reverse transcriptase
NPPOIMGL_04678 2.1e-145 L HNH nucleases
NPPOIMGL_04679 1.3e-75 umuC 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPPOIMGL_04680 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NPPOIMGL_04681 8.7e-38 xkdR S Protein of unknown function (DUF2577)
NPPOIMGL_04682 8.7e-176 yqbQ 3.2.1.96 G NLP P60 protein
NPPOIMGL_04683 2.9e-112 xkdP S Lysin motif
NPPOIMGL_04684 0.0 xkdO L Transglycosylase SLT domain
NPPOIMGL_04685 8.1e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
NPPOIMGL_04686 3.6e-76 xkdM S Phage tail tube protein
NPPOIMGL_04687 1e-249 xkdK S Phage tail sheath C-terminal domain
NPPOIMGL_04688 1.3e-24
NPPOIMGL_04689 1.9e-74
NPPOIMGL_04690 1.2e-86 S Bacteriophage HK97-gp10, putative tail-component
NPPOIMGL_04691 3.1e-62 yqbH S Domain of unknown function (DUF3599)
NPPOIMGL_04692 2.7e-67 S Protein of unknown function (DUF3199)
NPPOIMGL_04693 1.3e-45 S YqbF, hypothetical protein domain
NPPOIMGL_04694 3.2e-167 xkdG S Phage capsid family
NPPOIMGL_04695 3.1e-117 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NPPOIMGL_04696 1.3e-50 yrkC G Cupin domain
NPPOIMGL_04697 7.6e-23
NPPOIMGL_04698 7.8e-39 yrkD S protein conserved in bacteria
NPPOIMGL_04699 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
NPPOIMGL_04700 6.8e-46 P Rhodanese Homology Domain
NPPOIMGL_04701 1.4e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
NPPOIMGL_04702 1e-29 perX S DsrE/DsrF-like family
NPPOIMGL_04703 2.5e-206 yrkH P Rhodanese Homology Domain
NPPOIMGL_04704 1.6e-35 yrkI O Belongs to the sulfur carrier protein TusA family
NPPOIMGL_04705 6e-111 yrkJ S membrane transporter protein
NPPOIMGL_04706 1.9e-111 K COG1802 Transcriptional regulators
NPPOIMGL_04707 1e-179 yjlA EG Putative multidrug resistance efflux transporter
NPPOIMGL_04708 2.8e-79 S Protein of unknown function with HXXEE motif
NPPOIMGL_04709 1.5e-97 ywrO S Flavodoxin-like fold
NPPOIMGL_04710 1.6e-102 yrkN K Acetyltransferase (GNAT) family
NPPOIMGL_04711 7.7e-222 yrkO P Protein of unknown function (DUF418)
NPPOIMGL_04712 4.1e-127 T Transcriptional regulator
NPPOIMGL_04713 9.3e-234 yrkQ T Histidine kinase
NPPOIMGL_04714 2e-68 psiE S Protein PsiE homolog
NPPOIMGL_04715 1.2e-179 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPPOIMGL_04716 4.9e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NPPOIMGL_04717 1.1e-132 ydhQ K UTRA
NPPOIMGL_04718 9e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPPOIMGL_04719 4.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPPOIMGL_04720 5.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NPPOIMGL_04721 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NPPOIMGL_04722 4.6e-200 pbuE EGP Major facilitator Superfamily
NPPOIMGL_04723 2.4e-56 ydhK M Protein of unknown function (DUF1541)
NPPOIMGL_04724 2.3e-27 ydhK M Protein of unknown function (DUF1541)
NPPOIMGL_04725 4.9e-30 ydhK M Protein of unknown function (DUF1541)
NPPOIMGL_04726 8.1e-85 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPPOIMGL_04727 1.5e-35 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPPOIMGL_04728 1e-75 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPPOIMGL_04729 1.5e-14 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPPOIMGL_04730 8.6e-84 K Acetyltransferase (GNAT) domain
NPPOIMGL_04732 7.2e-61 frataxin S Domain of unknown function (DU1801)
NPPOIMGL_04733 4.4e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NPPOIMGL_04734 7.8e-89
NPPOIMGL_04735 2.8e-20
NPPOIMGL_04736 1.3e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NPPOIMGL_04737 5e-149 ydhD M Glycosyl hydrolase
NPPOIMGL_04738 1e-61 ydhD M Glycosyl hydrolase
NPPOIMGL_04739 3.2e-121 ydhC K FCD
NPPOIMGL_04740 1.2e-121 ydhB S membrane transporter protein
NPPOIMGL_04741 2.2e-208 tcaB EGP Major facilitator Superfamily
NPPOIMGL_04742 2.4e-69 ydgJ K Winged helix DNA-binding domain
NPPOIMGL_04743 1e-113 drgA C nitroreductase
NPPOIMGL_04744 0.0 ydgH S drug exporters of the RND superfamily
NPPOIMGL_04745 1.6e-60 K helix_turn_helix multiple antibiotic resistance protein
NPPOIMGL_04746 1.9e-41 dinB S DinB family
NPPOIMGL_04747 1.1e-47 dinB S DinB family
NPPOIMGL_04748 1.4e-69 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NPPOIMGL_04749 8.7e-178 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NPPOIMGL_04750 7.3e-298 expZ S ABC transporter
NPPOIMGL_04751 2e-55 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NPPOIMGL_04752 7.8e-55 ypuD
NPPOIMGL_04753 9.3e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NPPOIMGL_04754 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
NPPOIMGL_04755 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NPPOIMGL_04756 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NPPOIMGL_04757 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPPOIMGL_04758 1.4e-92 ypuF S Domain of unknown function (DUF309)
NPPOIMGL_04759 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPPOIMGL_04760 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPPOIMGL_04761 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NPPOIMGL_04762 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NPPOIMGL_04763 3.5e-103 spmA S Spore maturation protein
NPPOIMGL_04764 1.9e-87 spmB S Spore maturation protein
NPPOIMGL_04765 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPPOIMGL_04766 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NPPOIMGL_04767 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NPPOIMGL_04768 9.7e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NPPOIMGL_04769 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_04770 0.0 resE 2.7.13.3 T Histidine kinase
NPPOIMGL_04771 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_04772 1.1e-63 yngL S Protein of unknown function (DUF1360)
NPPOIMGL_04773 2e-304 yngK T Glycosyl hydrolase-like 10
NPPOIMGL_04774 1.4e-41 S Family of unknown function (DUF5367)
NPPOIMGL_04775 4.9e-109 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NPPOIMGL_04776 3.8e-102 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NPPOIMGL_04777 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NPPOIMGL_04778 1.1e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NPPOIMGL_04779 6.6e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NPPOIMGL_04780 1.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NPPOIMGL_04781 2.7e-135 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NPPOIMGL_04782 6.8e-136 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NPPOIMGL_04783 1e-125 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NPPOIMGL_04784 3.4e-85 nrnB S phosphohydrolase (DHH superfamily)
NPPOIMGL_04785 1.8e-153 nrnB S phosphohydrolase (DHH superfamily)
NPPOIMGL_04786 5.5e-104 yngC S membrane-associated protein
NPPOIMGL_04787 6.8e-159 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPPOIMGL_04788 1.6e-79 yngA S membrane
NPPOIMGL_04789 3.1e-56 ykuO
NPPOIMGL_04790 3.9e-147 ykuO
NPPOIMGL_04791 2.9e-84 fld C Flavodoxin domain
NPPOIMGL_04792 3.5e-168 ccpC K Transcriptional regulator
NPPOIMGL_04793 1.6e-76 ykuL S CBS domain
NPPOIMGL_04794 3.9e-27 ykzF S Antirepressor AbbA
NPPOIMGL_04795 4.4e-94 ykuK S Ribonuclease H-like
NPPOIMGL_04796 3.9e-37 ykuJ S protein conserved in bacteria
NPPOIMGL_04797 5.2e-234 ykuI T Diguanylate phosphodiesterase
NPPOIMGL_04799 0.0 3.2.1.132 M Putative peptidoglycan binding domain
NPPOIMGL_04800 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_04801 7.4e-163 ykuE S Metallophosphoesterase
NPPOIMGL_04802 8.6e-84 ykuD S protein conserved in bacteria
NPPOIMGL_04803 2.8e-238 ykuC EGP Major facilitator Superfamily
NPPOIMGL_04804 4.9e-84 ykyB S YkyB-like protein
NPPOIMGL_04805 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NPPOIMGL_04806 2.2e-15
NPPOIMGL_04807 6.3e-221 patA 2.6.1.1 E Aminotransferase
NPPOIMGL_04808 0.0 pilS 2.7.13.3 T Histidine kinase
NPPOIMGL_04809 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NPPOIMGL_04810 1.8e-123 ykwD J protein with SCP PR1 domains
NPPOIMGL_04811 1.1e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NPPOIMGL_04812 1.3e-248 mcpC NT chemotaxis protein
NPPOIMGL_04813 1.9e-124 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPPOIMGL_04814 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
NPPOIMGL_04815 7.2e-39 splA S Transcriptional regulator
NPPOIMGL_04816 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPPOIMGL_04817 2.1e-39 ptsH G phosphocarrier protein HPr
NPPOIMGL_04818 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPPOIMGL_04819 7.6e-128 glcT K antiterminator
NPPOIMGL_04820 4.1e-178 ykvZ 5.1.1.1 K Transcriptional regulator
NPPOIMGL_04821 2.5e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NPPOIMGL_04822 5e-09
NPPOIMGL_04823 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NPPOIMGL_04824 9.2e-89 stoA CO thiol-disulfide
NPPOIMGL_04825 1.1e-237 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPPOIMGL_04826 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NPPOIMGL_04827 2.8e-28
NPPOIMGL_04828 6e-25 ykvS S protein conserved in bacteria
NPPOIMGL_04829 2.1e-45 ykvR S Protein of unknown function (DUF3219)
NPPOIMGL_04830 1.1e-162 G Glycosyl hydrolases family 18
NPPOIMGL_04831 3.5e-35 3.5.1.104 M LysM domain
NPPOIMGL_04832 6.2e-232 ykvP 3.5.1.28 M Glycosyl transferases group 1
NPPOIMGL_04833 7e-133 IQ Enoyl-(Acyl carrier protein) reductase
NPPOIMGL_04834 2.2e-60 ykvN K HxlR-like helix-turn-helix
NPPOIMGL_04835 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NPPOIMGL_04836 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NPPOIMGL_04837 1.8e-80 queD 4.1.2.50, 4.2.3.12 H synthase
NPPOIMGL_04838 7.8e-44 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NPPOIMGL_04839 2.9e-61 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NPPOIMGL_04840 3.3e-181 ykvI S membrane
NPPOIMGL_04841 0.0 clpE O Belongs to the ClpA ClpB family
NPPOIMGL_04842 1e-137 motA N flagellar motor
NPPOIMGL_04843 2.5e-125 motB N Flagellar motor protein
NPPOIMGL_04844 1.3e-75 ykvE K transcriptional
NPPOIMGL_04845 2.4e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NPPOIMGL_04846 1.8e-64 eag
NPPOIMGL_04847 7.5e-10 S Spo0E like sporulation regulatory protein
NPPOIMGL_04848 1.1e-50 XK27_09985 S Protein of unknown function (DUF1232)
NPPOIMGL_04849 5.4e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NPPOIMGL_04850 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NPPOIMGL_04851 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NPPOIMGL_04852 1.2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NPPOIMGL_04853 5.2e-231 mtnE 2.6.1.83 E Aminotransferase
NPPOIMGL_04854 1.7e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NPPOIMGL_04855 3.7e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NPPOIMGL_04856 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NPPOIMGL_04858 5.9e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPPOIMGL_04859 8.9e-184 kinE 2.7.13.3 T Histidine kinase
NPPOIMGL_04860 2.9e-238 kinE 2.7.13.3 T Histidine kinase
NPPOIMGL_04861 3.2e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NPPOIMGL_04862 1.4e-18 ykzE
NPPOIMGL_04863 1.2e-10 ydfR S Protein of unknown function (DUF421)
NPPOIMGL_04864 2.9e-228 ktrB P COG0168 Trk-type K transport systems, membrane components
NPPOIMGL_04865 3.5e-155 htpX O Belongs to the peptidase M48B family
NPPOIMGL_04866 2.5e-124 ykrK S Domain of unknown function (DUF1836)
NPPOIMGL_04867 1.9e-26 sspD S small acid-soluble spore protein
NPPOIMGL_04868 6.7e-111 rsgI S Anti-sigma factor N-terminus
NPPOIMGL_04869 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NPPOIMGL_04870 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NPPOIMGL_04871 1.4e-102 ykoX S membrane-associated protein
NPPOIMGL_04872 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_04873 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_04874 1.7e-257 iolT EGP Major facilitator Superfamily
NPPOIMGL_04875 2e-46 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NPPOIMGL_04876 1.8e-93 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NPPOIMGL_04877 4.5e-64 ydjM M Lytic transglycolase
NPPOIMGL_04878 9.1e-155 ydjN U Involved in the tonB-independent uptake of proteins
NPPOIMGL_04880 1.4e-34 ydjO S Cold-inducible protein YdjO
NPPOIMGL_04881 4.4e-157 ydjP I Alpha/beta hydrolase family
NPPOIMGL_04882 1.3e-174 yeaA S Protein of unknown function (DUF4003)
NPPOIMGL_04883 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NPPOIMGL_04884 9.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NPPOIMGL_04885 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NPPOIMGL_04886 3.9e-176 yeaC S COG0714 MoxR-like ATPases
NPPOIMGL_04887 3.8e-59 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NPPOIMGL_04888 2.7e-146 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NPPOIMGL_04889 0.0 yebA E COG1305 Transglutaminase-like enzymes
NPPOIMGL_04890 3.7e-176 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NPPOIMGL_04891 6.3e-87 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NPPOIMGL_04892 2e-38
NPPOIMGL_04893 1.1e-87 K Belongs to the sigma-70 factor family. ECF subfamily
NPPOIMGL_04894 9.8e-248 S Domain of unknown function (DUF4179)
NPPOIMGL_04895 1.8e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NPPOIMGL_04896 4e-97 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NPPOIMGL_04897 8.4e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NPPOIMGL_04898 2e-116 ywqC M biosynthesis protein
NPPOIMGL_04899 1.2e-17
NPPOIMGL_04900 2.7e-307 ywqB S SWIM zinc finger
NPPOIMGL_04901 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NPPOIMGL_04902 3.9e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NPPOIMGL_04903 9.2e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NPPOIMGL_04904 3.7e-57 ssbB L Single-stranded DNA-binding protein
NPPOIMGL_04905 3.8e-66 ywpG
NPPOIMGL_04906 1.1e-66 ywpF S YwpF-like protein
NPPOIMGL_04907 1.8e-84 srtA 3.4.22.70 M Sortase family
NPPOIMGL_04908 1.1e-95 M1-568 M cell wall anchor domain
NPPOIMGL_04909 2.7e-40 ywpD T PhoQ Sensor
NPPOIMGL_04910 1.7e-211 pbuG S permease
NPPOIMGL_04911 2.3e-118 yebC M Membrane
NPPOIMGL_04913 8.9e-93 yebE S UPF0316 protein
NPPOIMGL_04914 8e-28 yebG S NETI protein
NPPOIMGL_04915 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NPPOIMGL_04916 3e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NPPOIMGL_04917 3.3e-38 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPPOIMGL_04918 5.8e-194 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPPOIMGL_04919 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NPPOIMGL_04920 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPPOIMGL_04921 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPPOIMGL_04922 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NPPOIMGL_04923 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NPPOIMGL_04924 8.7e-167 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NPPOIMGL_04925 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NPPOIMGL_04926 1.1e-109 spaB S Lantibiotic dehydratase, C terminus
NPPOIMGL_04927 1.7e-86 spaB S Lantibiotic dehydratase, C terminus
NPPOIMGL_04928 4.2e-155 spaT V ABC transporter
NPPOIMGL_04929 7.1e-96 spaC2 V PFAM Lanthionine synthetase
NPPOIMGL_04930 1.1e-09 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
NPPOIMGL_04932 4.2e-103 mutF V ABC transporter, ATP-binding protein
NPPOIMGL_04933 1.3e-86 spaE S ABC-2 family transporter protein
NPPOIMGL_04934 7e-80 mutG S ABC-2 family transporter protein
NPPOIMGL_04935 2.5e-105 K Transcriptional regulatory protein, C terminal
NPPOIMGL_04936 9.2e-155 T His Kinase A (phosphoacceptor) domain
NPPOIMGL_04937 2.4e-209 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NPPOIMGL_04938 1e-225 ywoF P Right handed beta helix region
NPPOIMGL_04940 2.7e-211 ywoG EGP Major facilitator Superfamily
NPPOIMGL_04941 2.1e-70 ywoH K COG1846 Transcriptional regulators
NPPOIMGL_04942 3e-44 spoIIID K Stage III sporulation protein D
NPPOIMGL_04943 3.5e-180 mbl D Rod shape-determining protein
NPPOIMGL_04944 5.8e-125 flhO N flagellar basal body
NPPOIMGL_04945 1.1e-139 flhP N flagellar basal body
NPPOIMGL_04946 2.6e-197 S aspartate phosphatase
NPPOIMGL_04947 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NPPOIMGL_04948 1.9e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPPOIMGL_04949 1.4e-137 ywpD T Histidine kinase
NPPOIMGL_04950 3.8e-96 S Protein of unknown function (DUF421)
NPPOIMGL_04951 5.4e-286 clsA_1 I PLD-like domain
NPPOIMGL_04952 6.4e-41 S Protein of unknown function (DUF421)
NPPOIMGL_04953 1.9e-150 yetF1 S membrane
NPPOIMGL_04954 5.8e-29 S Protein of unknown function (DUF1657)
NPPOIMGL_04955 8.5e-57 spoVAE S stage V sporulation protein
NPPOIMGL_04956 1e-195 spoVAD I Stage V sporulation protein AD
NPPOIMGL_04957 2.6e-80 spoVAC S stage V sporulation protein AC
NPPOIMGL_04958 2.6e-77 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NPPOIMGL_04959 7.1e-27 S Protein of unknown function (DUF1657)
NPPOIMGL_04960 1.1e-23 cat P Catalase
NPPOIMGL_04961 9.4e-161 cat P Catalase
NPPOIMGL_04962 2.9e-25 S Protein of unknown function (DUF2642)
NPPOIMGL_04963 5.3e-67 S TIGRFAM germination protein, Ger(x)C family
NPPOIMGL_04964 3.3e-154 EG Spore germination protein
NPPOIMGL_04965 8.2e-32 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NPPOIMGL_04966 1.7e-76
NPPOIMGL_04967 2.4e-68 L Transposase and inactivated derivatives, TnpA family
NPPOIMGL_04968 6.3e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NPPOIMGL_04969 4.6e-121 1.14.11.45 E 2OG-Fe dioxygenase
NPPOIMGL_04970 1.8e-72 yxiE T Belongs to the universal stress protein A family
NPPOIMGL_04971 2.9e-273 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPPOIMGL_04972 3.3e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPPOIMGL_04973 3.2e-21 S Immunity protein 8
NPPOIMGL_04974 7.3e-84 S nuclease activity
NPPOIMGL_04975 5.5e-53
NPPOIMGL_04976 3.8e-158 S nuclease activity
NPPOIMGL_04977 9.3e-66 S nuclease activity
NPPOIMGL_04978 1.4e-38 yxiC S Family of unknown function (DUF5344)
NPPOIMGL_04979 4.6e-21 S Domain of unknown function (DUF5082)
NPPOIMGL_04980 0.0 L HKD family nuclease
NPPOIMGL_04981 6.9e-126 tcaA S response to antibiotic
NPPOIMGL_04982 1.4e-59 exoY M Membrane
NPPOIMGL_04983 8.6e-113 yvbH S YvbH-like oligomerisation region
NPPOIMGL_04984 2.4e-102 yvbG U UPF0056 membrane protein
NPPOIMGL_04985 3.5e-97 yvbF K Belongs to the GbsR family
NPPOIMGL_04986 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NPPOIMGL_04987 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NPPOIMGL_04988 4.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPPOIMGL_04989 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NPPOIMGL_04990 7.4e-60 yvbF K Belongs to the GbsR family
NPPOIMGL_04991 1.8e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NPPOIMGL_04992 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NPPOIMGL_04993 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPPOIMGL_04994 2.9e-100 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NPPOIMGL_04995 2.5e-209 ywbN P Dyp-type peroxidase family protein
NPPOIMGL_04996 2.1e-184 ycdO P periplasmic lipoprotein involved in iron transport
NPPOIMGL_04997 1.5e-191 P COG0672 High-affinity Fe2 Pb2 permease
NPPOIMGL_04998 1.1e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NPPOIMGL_04999 9e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NPPOIMGL_05000 1.6e-152 ywbI K Transcriptional regulator
NPPOIMGL_05001 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NPPOIMGL_05002 1.3e-109 ywbG M effector of murein hydrolase
NPPOIMGL_05003 3.2e-131 ywbF EGP Major facilitator Superfamily
NPPOIMGL_05004 1.5e-68 ywbF EGP Major facilitator Superfamily
NPPOIMGL_05005 2.9e-26 ywbE S Uncharacterized conserved protein (DUF2196)
NPPOIMGL_05006 2.5e-159 ywbD 2.1.1.191 J Methyltransferase
NPPOIMGL_05007 1.9e-303 ytcJ S amidohydrolase
NPPOIMGL_05008 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NPPOIMGL_05009 2e-29 sspB S spore protein
NPPOIMGL_05010 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPPOIMGL_05011 1.2e-208 iscS2 2.8.1.7 E Cysteine desulfurase
NPPOIMGL_05012 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NPPOIMGL_05013 1.3e-272 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPPOIMGL_05014 3.6e-79 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NPPOIMGL_05015 6.3e-81 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NPPOIMGL_05016 3.8e-108 yttP K Transcriptional regulator
NPPOIMGL_05017 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NPPOIMGL_05018 1.2e-267 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NPPOIMGL_05019 1.3e-54 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NPPOIMGL_05020 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPPOIMGL_05022 4.6e-230 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPPOIMGL_05023 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NPPOIMGL_05024 8.9e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NPPOIMGL_05025 1.2e-35 acuB S Domain in cystathionine beta-synthase and other proteins.
NPPOIMGL_05026 5.3e-62 acuB S Domain in cystathionine beta-synthase and other proteins.
NPPOIMGL_05027 9.3e-178 acuC BQ histone deacetylase
NPPOIMGL_05028 5.9e-46 acuC BQ histone deacetylase
NPPOIMGL_05029 5.2e-125 motS N Flagellar motor protein
NPPOIMGL_05030 2.1e-146 motA N flagellar motor
NPPOIMGL_05031 3.8e-182 ccpA K catabolite control protein A
NPPOIMGL_05032 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NPPOIMGL_05033 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
NPPOIMGL_05034 6.6e-17 ytxH S COG4980 Gas vesicle protein
NPPOIMGL_05035 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPPOIMGL_05036 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NPPOIMGL_05037 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NPPOIMGL_05038 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPPOIMGL_05039 9.8e-149 ytpQ S Belongs to the UPF0354 family
NPPOIMGL_05040 1.3e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NPPOIMGL_05041 3.7e-74 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NPPOIMGL_05042 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NPPOIMGL_05043 2.2e-51 ytzB S small secreted protein
NPPOIMGL_05044 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NPPOIMGL_05045 3.8e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NPPOIMGL_05046 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPPOIMGL_05047 2e-45 ytzH S YtzH-like protein
NPPOIMGL_05048 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NPPOIMGL_05049 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NPPOIMGL_05050 1.7e-137 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NPPOIMGL_05051 5.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NPPOIMGL_05052 6.5e-165 ytlQ
NPPOIMGL_05053 2.7e-32 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NPPOIMGL_05054 2.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPPOIMGL_05055 1.3e-87 pepV 3.5.1.18 E Dipeptidase
NPPOIMGL_05056 1.9e-176 pepV 3.5.1.18 E Dipeptidase
NPPOIMGL_05057 6.1e-225 pbuO S permease
NPPOIMGL_05058 5.6e-68 ythQ U Bacterial ABC transporter protein EcsB
NPPOIMGL_05059 5.7e-102 ythQ U Bacterial ABC transporter protein EcsB
NPPOIMGL_05060 1.8e-130 ythP V ABC transporter
NPPOIMGL_05061 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NPPOIMGL_05062 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPPOIMGL_05063 1.2e-80 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPPOIMGL_05064 4.1e-207 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NPPOIMGL_05065 1.7e-240 ytfP S HI0933-like protein
NPPOIMGL_05066 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NPPOIMGL_05067 3.1e-26 yteV S Sporulation protein Cse60
NPPOIMGL_05068 8.5e-114 yteU S Integral membrane protein
NPPOIMGL_05069 3e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NPPOIMGL_05070 2.3e-72 yteS G transport
NPPOIMGL_05071 1.4e-200 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NPPOIMGL_05072 3.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NPPOIMGL_05073 0.0 ytdP K Transcriptional regulator
NPPOIMGL_05074 4.4e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NPPOIMGL_05075 2e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
NPPOIMGL_05076 1.1e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NPPOIMGL_05077 2.4e-84 bioI 1.14.14.46 C Cytochrome P450
NPPOIMGL_05078 2.6e-56 bioI 1.14.14.46 C Cytochrome P450
NPPOIMGL_05079 2.1e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NPPOIMGL_05080 5.9e-94 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NPPOIMGL_05081 8.9e-25 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NPPOIMGL_05082 1.6e-74 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NPPOIMGL_05083 5.5e-29 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NPPOIMGL_05084 1.9e-155 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NPPOIMGL_05085 3.1e-93 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NPPOIMGL_05086 1.5e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NPPOIMGL_05087 1.2e-171 ytaP S Acetyl xylan esterase (AXE1)
NPPOIMGL_05088 1e-94 msmR K Transcriptional regulator
NPPOIMGL_05089 1.1e-47 msmR K Transcriptional regulator
NPPOIMGL_05090 1.1e-53 msmE G Bacterial extracellular solute-binding protein
NPPOIMGL_05091 2.7e-168 msmE G Bacterial extracellular solute-binding protein
NPPOIMGL_05092 1.8e-167 amyD P ABC transporter
NPPOIMGL_05093 1.3e-143 amyC P ABC transporter (permease)
NPPOIMGL_05094 2.5e-116 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NPPOIMGL_05095 3e-130 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NPPOIMGL_05096 2.1e-51 ytwF P Sulfurtransferase
NPPOIMGL_05097 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPPOIMGL_05098 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NPPOIMGL_05099 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NPPOIMGL_05100 3.8e-192 yttB EGP Major facilitator Superfamily
NPPOIMGL_05101 4.3e-42 yttA 2.7.13.3 S Pfam Transposase IS66
NPPOIMGL_05102 0.0 bceB V ABC transporter (permease)
NPPOIMGL_05103 1.1e-138 bceA V ABC transporter, ATP-binding protein
NPPOIMGL_05104 4e-184 T PhoQ Sensor
NPPOIMGL_05105 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NPPOIMGL_05106 1.5e-229 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NPPOIMGL_05107 8.6e-19 ytrE V ABC transporter, ATP-binding protein
NPPOIMGL_05108 1.6e-32 ytrE V ABC transporter, ATP-binding protein
NPPOIMGL_05109 3.4e-29 yqaO S Phage-like element PBSX protein XtrA
NPPOIMGL_05110 2.4e-54 S Psort location Cytoplasmic, score
NPPOIMGL_05111 2.6e-75 S Beta protein
NPPOIMGL_05112 2.1e-76 L Transposase
NPPOIMGL_05116 1.3e-58
NPPOIMGL_05117 8e-69 yqaS L DNA packaging
NPPOIMGL_05118 4.2e-250 S phage terminase, large subunit
NPPOIMGL_05119 4.1e-289 yqbA S portal protein
NPPOIMGL_05120 1.5e-148 S Phage Mu protein F like protein
NPPOIMGL_05122 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NPPOIMGL_05123 1.1e-12 yubD P Major Facilitator Superfamily
NPPOIMGL_05124 7.5e-267 yubD P Major Facilitator Superfamily
NPPOIMGL_05125 3.2e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPPOIMGL_05126 1e-38 yiaA S yiaA/B two helix domain
NPPOIMGL_05127 3.9e-99 ktrB P Potassium
NPPOIMGL_05128 6.2e-86 ktrB P Potassium
NPPOIMGL_05129 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NPPOIMGL_05130 2.2e-91 yuaB
NPPOIMGL_05131 5.5e-95 yuaC K Belongs to the GbsR family
NPPOIMGL_05132 1.2e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NPPOIMGL_05133 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
NPPOIMGL_05134 1.1e-106 yuaD
NPPOIMGL_05135 3.9e-84 yuaE S DinB superfamily
NPPOIMGL_05136 5e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NPPOIMGL_05137 3.5e-187 yuaG 3.4.21.72 S protein conserved in bacteria
NPPOIMGL_05138 2.4e-92 M1-753 M FR47-like protein
NPPOIMGL_05139 1.3e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
NPPOIMGL_05140 1e-20 K Acetyltransferase (GNAT) family
NPPOIMGL_05141 5.1e-64 K Transcriptional regulator
NPPOIMGL_05142 1.3e-163 scrR K transcriptional
NPPOIMGL_05143 3.4e-228 msmE G Bacterial extracellular solute-binding protein
NPPOIMGL_05144 3.9e-149 msmF P Binding-protein-dependent transport system inner membrane component
NPPOIMGL_05145 1.1e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
NPPOIMGL_05146 2.1e-198 rafB P LacY proton/sugar symporter
NPPOIMGL_05147 2.7e-253 cscA 3.2.1.26 GH32 G invertase
NPPOIMGL_05148 4.6e-148 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
NPPOIMGL_05149 7.2e-74 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
NPPOIMGL_05150 4.1e-99 K NB-ARC domain
NPPOIMGL_05151 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NPPOIMGL_05152 5e-104 3.1.21.3 V Type I restriction modification DNA specificity domain
NPPOIMGL_05153 1.4e-287 hsdM 2.1.1.72 V Type I restriction-modification system
NPPOIMGL_05154 1.1e-80 3.1.21.3 V Type I restriction modification DNA specificity domain
NPPOIMGL_05155 4.6e-65 yozB S Membrane
NPPOIMGL_05159 4.8e-92 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPPOIMGL_05160 5.7e-11 K Cro/C1-type HTH DNA-binding domain
NPPOIMGL_05170 5.7e-160 S Calcineurin-like phosphoesterase
NPPOIMGL_05171 4.7e-29 sspB S spore protein
NPPOIMGL_05176 4.3e-63
NPPOIMGL_05178 4.1e-49 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPPOIMGL_05179 7.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NPPOIMGL_05180 1.2e-126 gntR K transcriptional
NPPOIMGL_05181 1.7e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NPPOIMGL_05182 5e-230 gntP EG COG2610 H gluconate symporter and related permeases
NPPOIMGL_05183 3.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPPOIMGL_05184 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NPPOIMGL_05185 4.3e-136 ahpF O Alkyl hydroperoxide reductase
NPPOIMGL_05186 6.2e-131 ahpF O Alkyl hydroperoxide reductase
NPPOIMGL_05187 5.6e-189 wgaE S Polysaccharide pyruvyl transferase
NPPOIMGL_05188 1.3e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPPOIMGL_05189 4.8e-12 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
NPPOIMGL_05190 5.2e-84 yydK K Transcriptional regulator
NPPOIMGL_05191 1.5e-43 yydK K Transcriptional regulator
NPPOIMGL_05192 5.3e-23 yydK K Transcriptional regulator
NPPOIMGL_05193 9.5e-119 S ABC-2 family transporter protein
NPPOIMGL_05194 5.9e-109 prrC P ABC transporter
NPPOIMGL_05195 5.8e-82 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NPPOIMGL_05196 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_05197 9e-142 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_05198 4.3e-203 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_05199 1.2e-63 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_05200 3.7e-168 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_05201 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_05202 1.6e-78 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_05203 1.2e-18 yoaP 3.1.3.18 K YoaP-like
NPPOIMGL_05205 4e-84
NPPOIMGL_05206 7.1e-172 yoaR V vancomycin resistance protein
NPPOIMGL_05207 1.8e-73 yoaS S Protein of unknown function (DUF2975)
NPPOIMGL_05208 4.4e-30 yozG K Transcriptional regulator
NPPOIMGL_05209 8.2e-148 yoaT S Protein of unknown function (DUF817)
NPPOIMGL_05210 4.3e-158 yoaU K LysR substrate binding domain
NPPOIMGL_05211 1e-154 yijE EG EamA-like transporter family
NPPOIMGL_05212 4.1e-29 yoaW
NPPOIMGL_05213 5.1e-66 yoaW
NPPOIMGL_05214 2.9e-60 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NPPOIMGL_05215 2.7e-58 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NPPOIMGL_05216 4.1e-167 bla 3.5.2.6 V beta-lactamase
NPPOIMGL_05217 3.2e-53 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPPOIMGL_05218 3.5e-260
NPPOIMGL_05219 4.2e-214 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NPPOIMGL_05220 6.3e-113 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPPOIMGL_05221 5.4e-68 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NPPOIMGL_05222 1.6e-181 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NPPOIMGL_05223 0.0 tagF 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPPOIMGL_05224 4e-145 tagG GM Transport permease protein
NPPOIMGL_05225 5.6e-21 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NPPOIMGL_05226 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_05227 1.8e-165 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPPOIMGL_05228 2.9e-282 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPPOIMGL_05229 6.9e-147 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPPOIMGL_05230 2.6e-118 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPPOIMGL_05231 6.6e-142 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPPOIMGL_05232 2e-81 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPPOIMGL_05233 4.5e-24 yqzJ
NPPOIMGL_05234 5.9e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPPOIMGL_05235 8.4e-54 yqjF S Uncharacterized conserved protein (COG2071)
NPPOIMGL_05237 2.5e-39 yqjF S Uncharacterized conserved protein (COG2071)
NPPOIMGL_05238 1.1e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NPPOIMGL_05239 2.7e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NPPOIMGL_05240 1.5e-49 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NPPOIMGL_05241 8.2e-67 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NPPOIMGL_05242 1.8e-98 yqjB S protein conserved in bacteria
NPPOIMGL_05243 4.1e-163 yqjA S Putative aromatic acid exporter C-terminal domain
NPPOIMGL_05244 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NPPOIMGL_05245 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NPPOIMGL_05246 1e-134 artP ET Belongs to the bacterial solute-binding protein 3 family
NPPOIMGL_05247 9.3e-77 yqiW S Belongs to the UPF0403 family
NPPOIMGL_05248 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NPPOIMGL_05249 3.9e-207 norA EGP Major facilitator Superfamily
NPPOIMGL_05250 2.6e-152 bmrR K helix_turn_helix, mercury resistance
NPPOIMGL_05251 1.8e-159 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPPOIMGL_05252 2.5e-44 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NPPOIMGL_05253 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NPPOIMGL_05254 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NPPOIMGL_05255 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NPPOIMGL_05256 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NPPOIMGL_05257 8.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NPPOIMGL_05258 5.1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NPPOIMGL_05259 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NPPOIMGL_05260 4e-34 yqzF S Protein of unknown function (DUF2627)
NPPOIMGL_05261 1.1e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NPPOIMGL_05262 7e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NPPOIMGL_05263 2.5e-115 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NPPOIMGL_05264 4.8e-71 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NPPOIMGL_05265 2e-208 mmgC I acyl-CoA dehydrogenase
NPPOIMGL_05266 2e-155 hbdA 1.1.1.157 I Dehydrogenase
NPPOIMGL_05267 5.9e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
NPPOIMGL_05268 1.1e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPPOIMGL_05269 1.7e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NPPOIMGL_05270 6e-27
NPPOIMGL_05271 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NPPOIMGL_05273 7e-40 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NPPOIMGL_05274 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NPPOIMGL_05275 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NPPOIMGL_05276 1.1e-306 recN L May be involved in recombinational repair of damaged DNA
NPPOIMGL_05277 5.7e-16 argR K Regulates arginine biosynthesis genes
NPPOIMGL_05278 1.5e-37 argR K Regulates arginine biosynthesis genes
NPPOIMGL_05279 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NPPOIMGL_05280 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPPOIMGL_05281 1.3e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPPOIMGL_05282 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPPOIMGL_05283 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPPOIMGL_05284 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPPOIMGL_05285 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPPOIMGL_05286 2.1e-67 yqhY S protein conserved in bacteria
NPPOIMGL_05287 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NPPOIMGL_05288 2.6e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPPOIMGL_05289 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NPPOIMGL_05290 2.2e-109 spoIIIAG S stage III sporulation protein AG
NPPOIMGL_05291 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NPPOIMGL_05292 6.4e-197 spoIIIAE S stage III sporulation protein AE
NPPOIMGL_05293 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NPPOIMGL_05294 7.6e-29 spoIIIAC S stage III sporulation protein AC
NPPOIMGL_05295 1.1e-84 spoIIIAB S Stage III sporulation protein
NPPOIMGL_05296 1.2e-112 spoIIIAA S stage III sporulation protein AA
NPPOIMGL_05297 2.2e-58 spoIIIAA S stage III sporulation protein AA
NPPOIMGL_05298 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NPPOIMGL_05299 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPPOIMGL_05300 2.2e-172 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NPPOIMGL_05301 3.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NPPOIMGL_05302 6.6e-93 yqhR S Conserved membrane protein YqhR
NPPOIMGL_05303 8.8e-173 yqhQ S Protein of unknown function (DUF1385)
NPPOIMGL_05304 2.2e-61 yqhP
NPPOIMGL_05305 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
NPPOIMGL_05306 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NPPOIMGL_05307 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NPPOIMGL_05308 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NPPOIMGL_05309 5.3e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NPPOIMGL_05310 2.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NPPOIMGL_05311 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NPPOIMGL_05312 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NPPOIMGL_05313 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
NPPOIMGL_05314 1.2e-24 sinI S Anti-repressor SinI
NPPOIMGL_05315 1e-54 sinR K transcriptional
NPPOIMGL_05316 4.3e-141 tasA S Cell division protein FtsN
NPPOIMGL_05317 7.4e-58 sipW 3.4.21.89 U Signal peptidase
NPPOIMGL_05318 1.5e-114 yqxM
NPPOIMGL_05319 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NPPOIMGL_05320 5.2e-26 yqzE S YqzE-like protein
NPPOIMGL_05321 8.8e-44 S ComG operon protein 7
NPPOIMGL_05322 7.2e-130 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NPPOIMGL_05323 2.8e-26 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NPPOIMGL_05324 1.5e-25 ssuA M Sulfonate ABC transporter
NPPOIMGL_05325 3.6e-169 ssuA M Sulfonate ABC transporter
NPPOIMGL_05326 5.6e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NPPOIMGL_05327 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NPPOIMGL_05329 1.1e-261 ygaK C Berberine and berberine like
NPPOIMGL_05330 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NPPOIMGL_05331 3.2e-173 gutB 1.1.1.14 E Dehydrogenase
NPPOIMGL_05332 8.2e-30 gutA G MFS/sugar transport protein
NPPOIMGL_05333 1.8e-70 gutA G MFS/sugar transport protein
NPPOIMGL_05334 1.1e-27 gutA G MFS/sugar transport protein
NPPOIMGL_05335 5e-137 gutA G MFS/sugar transport protein
NPPOIMGL_05336 2.6e-170 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NPPOIMGL_05337 8.7e-114 pspA KT Phage shock protein A
NPPOIMGL_05338 1.3e-27 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPPOIMGL_05339 9.8e-123 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPPOIMGL_05340 2.3e-70 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NPPOIMGL_05341 3.2e-66 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NPPOIMGL_05343 6.6e-97 K Transcriptional regulator
NPPOIMGL_05344 2.8e-126 yecA E amino acid
NPPOIMGL_05345 4.2e-81 T NACHT domain
NPPOIMGL_05346 2.1e-32 G Toxic component of a toxin-antitoxin (TA) module. An RNase
NPPOIMGL_05349 8.1e-50 S response regulator aspartate phosphatase
NPPOIMGL_05350 7.9e-33 C Domain of unknown function (DUF4145)
NPPOIMGL_05351 0.0 wapA M COG3209 Rhs family protein
NPPOIMGL_05354 4.6e-17 yxiG
NPPOIMGL_05355 9.3e-147 bltR K helix_turn_helix, mercury resistance
NPPOIMGL_05356 7.4e-209 blt EGP Major facilitator Superfamily
NPPOIMGL_05357 1.4e-80 bltD 2.3.1.57 K FR47-like protein
NPPOIMGL_05358 4.4e-231 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NPPOIMGL_05359 3.9e-16 S YrzO-like protein
NPPOIMGL_05360 7.1e-170 yrdR EG EamA-like transporter family
NPPOIMGL_05361 4.3e-158 yrdQ K Transcriptional regulator
NPPOIMGL_05362 1.4e-161 trkA P Oxidoreductase
NPPOIMGL_05363 9.6e-87 czcD P COG1230 Co Zn Cd efflux system component
NPPOIMGL_05364 1.7e-43 czcD P COG1230 Co Zn Cd efflux system component
NPPOIMGL_05365 1.5e-29 copZ P Copper resistance protein CopZ
NPPOIMGL_05366 2.2e-48 csoR S transcriptional
NPPOIMGL_05367 1.1e-181 yvaA 1.1.1.371 S Oxidoreductase
NPPOIMGL_05368 7.5e-41 yvaA 1.1.1.371 S Oxidoreductase
NPPOIMGL_05369 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NPPOIMGL_05370 0.0 yvaC S Fusaric acid resistance protein-like
NPPOIMGL_05371 1.3e-72 yvaD S Family of unknown function (DUF5360)
NPPOIMGL_05372 2e-53 yvaE P Small Multidrug Resistance protein
NPPOIMGL_05373 8.6e-99 K Bacterial regulatory proteins, tetR family
NPPOIMGL_05374 3.8e-65 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_05375 3.1e-48 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NPPOIMGL_05376 2e-70 S B-1 B cell differentiation
NPPOIMGL_05378 2.4e-53 S SMI1 / KNR4 family
NPPOIMGL_05379 1.3e-104 yokF 3.1.31.1 L RNA catabolic process
NPPOIMGL_05380 3.9e-13
NPPOIMGL_05381 1.8e-293 UW nuclease activity
NPPOIMGL_05382 1.2e-93 yokJ S SMI1 / KNR4 family (SUKH-1)
NPPOIMGL_05383 2.3e-50 D nuclear chromosome segregation
NPPOIMGL_05384 1.6e-27 S YolD-like protein
NPPOIMGL_05386 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NPPOIMGL_05387 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPPOIMGL_05388 5.6e-143 est 3.1.1.1 S Carboxylesterase
NPPOIMGL_05389 2.4e-23 secG U Preprotein translocase subunit SecG
NPPOIMGL_05390 5.3e-152 yvaM S Serine aminopeptidase, S33
NPPOIMGL_05392 9.8e-36 yvzC K Transcriptional
NPPOIMGL_05393 4e-69 K transcriptional
NPPOIMGL_05394 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
NPPOIMGL_05395 2.2e-54 yodB K transcriptional
NPPOIMGL_05396 3.4e-37 NT chemotaxis protein
NPPOIMGL_05397 6.6e-47 lysP E amino acid
NPPOIMGL_05398 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NPPOIMGL_05399 6.5e-232 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NPPOIMGL_05400 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NPPOIMGL_05401 9.8e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
NPPOIMGL_05402 6.7e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NPPOIMGL_05403 1.5e-258 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NPPOIMGL_05404 8.9e-46 L AAA domain
NPPOIMGL_05405 8.1e-210 L COG3385 FOG Transposase and inactivated derivatives
NPPOIMGL_05406 2.2e-83 L COG1112 Superfamily I DNA and RNA helicases and helicase subunits
NPPOIMGL_05407 2.3e-237 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPPOIMGL_05408 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NPPOIMGL_05409 1.7e-139 srfAD Q thioesterase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)