ORF_ID e_value Gene_name EC_number CAZy COGs Description
MLOALDAC_00001 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_00002 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
MLOALDAC_00003 4.1e-65 yngL S Protein of unknown function (DUF1360)
MLOALDAC_00004 3.8e-303 yngK T Glycosyl hydrolase-like 10
MLOALDAC_00005 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MLOALDAC_00006 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLOALDAC_00007 1.9e-253 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MLOALDAC_00008 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MLOALDAC_00009 2.5e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MLOALDAC_00010 3.4e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MLOALDAC_00011 2.4e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLOALDAC_00012 3.2e-104 yngC S SNARE associated Golgi protein
MLOALDAC_00013 4.2e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLOALDAC_00014 1.1e-71 yngA S membrane
MLOALDAC_00015 4.8e-145 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MLOALDAC_00016 3.5e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MLOALDAC_00017 3.3e-77 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLOALDAC_00018 4.2e-125 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLOALDAC_00019 3e-130 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MLOALDAC_00020 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MLOALDAC_00021 1.5e-225 bioI 1.14.14.46 C Cytochrome P450
MLOALDAC_00022 3.6e-255 yxjC EG COG2610 H gluconate symporter and related permeases
MLOALDAC_00023 4.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLOALDAC_00024 7.1e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLOALDAC_00025 6.9e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLOALDAC_00026 5.3e-223 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLOALDAC_00027 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_00028 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_00029 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_00030 1.1e-289 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MLOALDAC_00031 5.1e-253 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
MLOALDAC_00032 2.6e-129 T Transcriptional regulatory protein, C terminal
MLOALDAC_00033 1.8e-235 T PhoQ Sensor
MLOALDAC_00034 2.4e-50 S Domain of unknown function (DUF4870)
MLOALDAC_00035 1.6e-293 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MLOALDAC_00036 6.7e-212 S Platelet-activating factor acetylhydrolase, isoform II
MLOALDAC_00037 3.8e-12
MLOALDAC_00039 2.8e-63 V ABC transporter
MLOALDAC_00040 3.9e-83 S Protein of unknown function (DUF1430)
MLOALDAC_00041 4.1e-303 yndJ S YndJ-like protein
MLOALDAC_00042 3.1e-78 yndH S Domain of unknown function (DUF4166)
MLOALDAC_00043 1.8e-158 yndG S DoxX-like family
MLOALDAC_00044 1.1e-223 exuT G Sugar (and other) transporter
MLOALDAC_00045 1.9e-181 kdgR_1 K transcriptional
MLOALDAC_00046 2e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLOALDAC_00047 1e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MLOALDAC_00048 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MLOALDAC_00049 5.3e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MLOALDAC_00050 1e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MLOALDAC_00051 3.2e-251 agcS E Sodium alanine symporter
MLOALDAC_00052 5.1e-41 ynfC
MLOALDAC_00053 4.6e-13
MLOALDAC_00054 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLOALDAC_00055 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MLOALDAC_00056 1.5e-68 yccU S CoA-binding protein
MLOALDAC_00057 1.4e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MLOALDAC_00058 1.3e-50 yneR S Belongs to the HesB IscA family
MLOALDAC_00059 7.5e-54 yneQ
MLOALDAC_00060 8.3e-75 yneP S Thioesterase-like superfamily
MLOALDAC_00061 2.7e-33 tlp S Belongs to the Tlp family
MLOALDAC_00063 3.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MLOALDAC_00064 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MLOALDAC_00065 7.5e-15 sspO S Belongs to the SspO family
MLOALDAC_00066 2.3e-19 sspP S Belongs to the SspP family
MLOALDAC_00067 3.2e-62 hspX O Spore coat protein
MLOALDAC_00068 8.5e-75 yneK S Protein of unknown function (DUF2621)
MLOALDAC_00069 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MLOALDAC_00070 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MLOALDAC_00071 1.7e-125 ccdA O cytochrome c biogenesis protein
MLOALDAC_00072 2.1e-23 ynzD S Spo0E like sporulation regulatory protein
MLOALDAC_00073 2.3e-28 yneF S UPF0154 protein
MLOALDAC_00074 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
MLOALDAC_00075 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MLOALDAC_00076 9.8e-33 ynzC S UPF0291 protein
MLOALDAC_00077 3.5e-112 yneB L resolvase
MLOALDAC_00078 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MLOALDAC_00079 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLOALDAC_00080 4.6e-12 yoaW
MLOALDAC_00081 2.4e-72 yndM S Protein of unknown function (DUF2512)
MLOALDAC_00082 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
MLOALDAC_00083 1.6e-07
MLOALDAC_00084 1.1e-144 yndL S Replication protein
MLOALDAC_00085 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MLOALDAC_00086 0.0 yobO M Pectate lyase superfamily protein
MLOALDAC_00088 1e-93 yvgO
MLOALDAC_00090 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
MLOALDAC_00091 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLOALDAC_00092 7.5e-54 ynaE S Domain of unknown function (DUF3885)
MLOALDAC_00093 1.6e-42 ynaE S Domain of unknown function (DUF3885)
MLOALDAC_00096 5.3e-36
MLOALDAC_00097 2.4e-98 J Acetyltransferase (GNAT) domain
MLOALDAC_00098 8.1e-145 yoaP 3.1.3.18 K YoaP-like
MLOALDAC_00100 1.1e-186 adhP 1.1.1.1 C alcohol dehydrogenase
MLOALDAC_00101 2.1e-52 dinB S DinB family
MLOALDAC_00102 3e-14
MLOALDAC_00108 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MLOALDAC_00109 2.4e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
MLOALDAC_00110 1.1e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MLOALDAC_00111 1.2e-216 xylR GK ROK family
MLOALDAC_00112 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MLOALDAC_00113 1.3e-252 xynT G MFS/sugar transport protein
MLOALDAC_00114 6.9e-214 mrjp G Major royal jelly protein
MLOALDAC_00116 3.2e-94
MLOALDAC_00117 1.3e-14
MLOALDAC_00118 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
MLOALDAC_00119 4.3e-68 glnR K transcriptional
MLOALDAC_00120 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MLOALDAC_00121 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLOALDAC_00122 1.3e-176 spoVK O stage V sporulation protein K
MLOALDAC_00123 6.2e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLOALDAC_00124 2.4e-110 ymaB S MutT family
MLOALDAC_00125 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLOALDAC_00126 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLOALDAC_00127 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MLOALDAC_00128 1.8e-20 ymzA
MLOALDAC_00129 8.5e-44
MLOALDAC_00130 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MLOALDAC_00131 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLOALDAC_00132 1.4e-47 ymaF S YmaF family
MLOALDAC_00134 3.1e-48 ebrA P Small Multidrug Resistance protein
MLOALDAC_00135 5.2e-54 ebrB P Small Multidrug Resistance protein
MLOALDAC_00136 6e-79 ymaD O redox protein, regulator of disulfide bond formation
MLOALDAC_00137 4.1e-127 ymaC S Replication protein
MLOALDAC_00139 8.9e-256 aprX O Belongs to the peptidase S8 family
MLOALDAC_00140 1.4e-62 ymzB
MLOALDAC_00141 1e-117 yoaK S Membrane
MLOALDAC_00142 4.1e-77 nucB M Deoxyribonuclease NucA/NucB
MLOALDAC_00143 9e-231 cypA C Cytochrome P450
MLOALDAC_00144 0.0 pks13 HQ Beta-ketoacyl synthase
MLOALDAC_00145 0.0 dhbF IQ polyketide synthase
MLOALDAC_00146 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
MLOALDAC_00147 0.0 Q Polyketide synthase of type I
MLOALDAC_00148 0.0 rhiB IQ polyketide synthase
MLOALDAC_00149 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
MLOALDAC_00150 5.3e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
MLOALDAC_00151 2.2e-243 pksG 2.3.3.10 I synthase
MLOALDAC_00152 2.9e-35 acpK IQ Phosphopantetheine attachment site
MLOALDAC_00153 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLOALDAC_00154 5.6e-183 pksD Q Acyl transferase domain
MLOALDAC_00155 3.7e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLOALDAC_00156 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
MLOALDAC_00158 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLOALDAC_00159 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLOALDAC_00160 1.7e-88 cotE S Spore coat protein
MLOALDAC_00161 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MLOALDAC_00162 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MLOALDAC_00163 6.1e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MLOALDAC_00164 1.7e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MLOALDAC_00165 1.2e-36 spoVS S Stage V sporulation protein S
MLOALDAC_00166 4.9e-153 ymdB S protein conserved in bacteria
MLOALDAC_00167 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
MLOALDAC_00168 2.1e-192 pbpX V Beta-lactamase
MLOALDAC_00169 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLOALDAC_00170 3.8e-232 cinA 3.5.1.42 S Belongs to the CinA family
MLOALDAC_00171 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLOALDAC_00172 1.7e-125 ymfM S protein conserved in bacteria
MLOALDAC_00173 3.5e-143 ymfK S Protein of unknown function (DUF3388)
MLOALDAC_00174 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
MLOALDAC_00175 3.9e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MLOALDAC_00176 6.4e-243 ymfH S zinc protease
MLOALDAC_00177 1.2e-238 ymfF S Peptidase M16
MLOALDAC_00178 0.0 ydgH S drug exporters of the RND superfamily
MLOALDAC_00179 4e-75 K helix_turn_helix multiple antibiotic resistance protein
MLOALDAC_00180 2.4e-229 ymfD EGP Major facilitator Superfamily
MLOALDAC_00181 1.8e-133 ymfC K Transcriptional regulator
MLOALDAC_00182 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MLOALDAC_00183 6.3e-31 S YlzJ-like protein
MLOALDAC_00184 2.9e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MLOALDAC_00185 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLOALDAC_00186 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLOALDAC_00187 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MLOALDAC_00188 7.6e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLOALDAC_00189 1.7e-105 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MLOALDAC_00190 1.2e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MLOALDAC_00191 2.6e-42 ymxH S YlmC YmxH family
MLOALDAC_00192 3.6e-235 pepR S Belongs to the peptidase M16 family
MLOALDAC_00193 8e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MLOALDAC_00194 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MLOALDAC_00195 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLOALDAC_00196 3.5e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MLOALDAC_00197 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLOALDAC_00198 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLOALDAC_00199 3.9e-44 ylxP S protein conserved in bacteria
MLOALDAC_00200 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLOALDAC_00201 1.8e-47 ylxQ J ribosomal protein
MLOALDAC_00202 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
MLOALDAC_00203 5.4e-206 nusA K Participates in both transcription termination and antitermination
MLOALDAC_00204 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
MLOALDAC_00205 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLOALDAC_00206 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MLOALDAC_00207 1.5e-233 rasP M zinc metalloprotease
MLOALDAC_00208 7.3e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MLOALDAC_00209 9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
MLOALDAC_00210 2.9e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLOALDAC_00211 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MLOALDAC_00212 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MLOALDAC_00213 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLOALDAC_00214 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MLOALDAC_00215 4e-54 ylxL
MLOALDAC_00216 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLOALDAC_00217 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MLOALDAC_00218 1.6e-109 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MLOALDAC_00219 2.5e-80 cheW NT COG0835 Chemotaxis signal transduction protein
MLOALDAC_00220 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MLOALDAC_00221 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MLOALDAC_00222 5.9e-155 flhG D Belongs to the ParA family
MLOALDAC_00223 6.7e-193 flhF N Flagellar biosynthesis regulator FlhF
MLOALDAC_00224 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLOALDAC_00225 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLOALDAC_00226 5.2e-131 fliR N Flagellar biosynthetic protein FliR
MLOALDAC_00227 2e-37 fliQ N Role in flagellar biosynthesis
MLOALDAC_00228 4.3e-110 fliP N Plays a role in the flagellum-specific transport system
MLOALDAC_00229 1.9e-110 fliZ N Flagellar biosynthesis protein, FliO
MLOALDAC_00230 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MLOALDAC_00231 1e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLOALDAC_00232 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLOALDAC_00233 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
MLOALDAC_00234 4e-139 flgG N Flagellar basal body rod
MLOALDAC_00235 4.2e-64 flgD N Flagellar basal body rod modification protein
MLOALDAC_00236 7.2e-205 fliK N Flagellar hook-length control protein
MLOALDAC_00237 4.4e-48 ylxF S MgtE intracellular N domain
MLOALDAC_00238 4.5e-71 fliJ N Flagellar biosynthesis chaperone
MLOALDAC_00239 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MLOALDAC_00240 1.4e-88 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MLOALDAC_00241 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MLOALDAC_00242 1.4e-263 fliF N The M ring may be actively involved in energy transduction
MLOALDAC_00243 2.5e-31 fliE N Flagellar hook-basal body
MLOALDAC_00244 2.4e-75 flgC N Belongs to the flagella basal body rod proteins family
MLOALDAC_00245 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MLOALDAC_00246 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MLOALDAC_00247 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MLOALDAC_00248 2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MLOALDAC_00249 7.2e-172 xerC L tyrosine recombinase XerC
MLOALDAC_00250 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLOALDAC_00251 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLOALDAC_00252 5.6e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MLOALDAC_00253 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MLOALDAC_00254 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MLOALDAC_00255 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MLOALDAC_00256 2.2e-307 ylqG
MLOALDAC_00257 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLOALDAC_00258 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MLOALDAC_00259 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MLOALDAC_00260 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MLOALDAC_00261 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLOALDAC_00262 1.3e-61 ylqD S YlqD protein
MLOALDAC_00263 1.7e-35 ylqC S Belongs to the UPF0109 family
MLOALDAC_00264 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MLOALDAC_00265 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLOALDAC_00266 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MLOALDAC_00267 4.7e-140 S Phosphotransferase enzyme family
MLOALDAC_00268 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MLOALDAC_00269 0.0 smc D Required for chromosome condensation and partitioning
MLOALDAC_00270 1.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MLOALDAC_00271 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLOALDAC_00272 4.6e-129 IQ reductase
MLOALDAC_00273 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLOALDAC_00274 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MLOALDAC_00275 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MLOALDAC_00276 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLOALDAC_00277 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
MLOALDAC_00278 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
MLOALDAC_00279 2.1e-302 yloV S kinase related to dihydroxyacetone kinase
MLOALDAC_00280 5.5e-59 asp S protein conserved in bacteria
MLOALDAC_00281 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MLOALDAC_00282 1.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
MLOALDAC_00283 1.7e-114 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MLOALDAC_00284 5.7e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MLOALDAC_00285 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MLOALDAC_00286 1.7e-139 stp 3.1.3.16 T phosphatase
MLOALDAC_00287 1.2e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MLOALDAC_00288 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLOALDAC_00289 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLOALDAC_00290 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLOALDAC_00291 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLOALDAC_00292 2.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLOALDAC_00293 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MLOALDAC_00294 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MLOALDAC_00295 1.5e-40 ylzA S Belongs to the UPF0296 family
MLOALDAC_00296 1e-154 yloC S stress-induced protein
MLOALDAC_00297 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MLOALDAC_00298 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MLOALDAC_00299 2.2e-79 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MLOALDAC_00300 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MLOALDAC_00301 1.4e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MLOALDAC_00302 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MLOALDAC_00303 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MLOALDAC_00304 1.7e-177 cysP P phosphate transporter
MLOALDAC_00305 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MLOALDAC_00306 4.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLOALDAC_00307 4.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MLOALDAC_00308 1.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MLOALDAC_00309 7.7e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MLOALDAC_00310 0.0 carB 6.3.5.5 F Belongs to the CarB family
MLOALDAC_00311 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MLOALDAC_00312 8.6e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MLOALDAC_00313 3.1e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MLOALDAC_00314 1.8e-232 pyrP F Xanthine uracil
MLOALDAC_00315 6.7e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MLOALDAC_00316 1.8e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLOALDAC_00317 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLOALDAC_00318 3.4e-64 dksA T COG1734 DnaK suppressor protein
MLOALDAC_00319 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLOALDAC_00320 8.9e-68 divIVA D Cell division initiation protein
MLOALDAC_00321 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MLOALDAC_00322 5.2e-41 yggT S membrane
MLOALDAC_00323 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MLOALDAC_00324 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLOALDAC_00325 3.4e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MLOALDAC_00326 2.2e-38 ylmC S sporulation protein
MLOALDAC_00327 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
MLOALDAC_00328 4.5e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MLOALDAC_00329 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLOALDAC_00330 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLOALDAC_00331 9.8e-161 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MLOALDAC_00332 0.0 bpr O COG1404 Subtilisin-like serine proteases
MLOALDAC_00333 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLOALDAC_00334 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MLOALDAC_00335 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MLOALDAC_00336 5.6e-169 murB 1.3.1.98 M cell wall formation
MLOALDAC_00337 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLOALDAC_00338 2.2e-185 spoVE D Belongs to the SEDS family
MLOALDAC_00339 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLOALDAC_00340 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLOALDAC_00341 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLOALDAC_00342 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MLOALDAC_00343 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MLOALDAC_00344 2.9e-52 ftsL D Essential cell division protein
MLOALDAC_00345 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MLOALDAC_00346 8.9e-78 mraZ K Belongs to the MraZ family
MLOALDAC_00347 2.3e-311 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MLOALDAC_00348 1.1e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLOALDAC_00349 1.2e-88 ylbP K n-acetyltransferase
MLOALDAC_00350 4.5e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MLOALDAC_00351 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MLOALDAC_00352 7.8e-91 yceD S metal-binding, possibly nucleic acid-binding protein
MLOALDAC_00353 5.4e-231 ylbM S Belongs to the UPF0348 family
MLOALDAC_00354 2.1e-188 ylbL T Belongs to the peptidase S16 family
MLOALDAC_00355 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
MLOALDAC_00356 9.8e-217 ylbJ S Sporulation integral membrane protein YlbJ
MLOALDAC_00357 3.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLOALDAC_00358 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
MLOALDAC_00360 7.2e-43 ylbG S UPF0298 protein
MLOALDAC_00361 1.2e-71 ylbF S Belongs to the UPF0342 family
MLOALDAC_00362 8.8e-37 ylbE S YlbE-like protein
MLOALDAC_00363 6.5e-56 ylbD S Putative coat protein
MLOALDAC_00364 2.1e-199 ylbC S protein with SCP PR1 domains
MLOALDAC_00365 2.2e-73 ylbB T COG0517 FOG CBS domain
MLOALDAC_00366 8.5e-60 ylbA S YugN-like family
MLOALDAC_00367 9.7e-166 ctaG S cytochrome c oxidase
MLOALDAC_00368 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MLOALDAC_00369 3.1e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MLOALDAC_00370 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLOALDAC_00371 1.5e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MLOALDAC_00372 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLOALDAC_00373 2.9e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MLOALDAC_00374 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MLOALDAC_00375 7.7e-214 ftsW D Belongs to the SEDS family
MLOALDAC_00376 8.7e-44 ylaN S Belongs to the UPF0358 family
MLOALDAC_00377 5.4e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
MLOALDAC_00378 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MLOALDAC_00379 3.7e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MLOALDAC_00380 5.1e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLOALDAC_00381 1e-33 ylaI S protein conserved in bacteria
MLOALDAC_00382 1.7e-48 ylaH S YlaH-like protein
MLOALDAC_00383 0.0 typA T GTP-binding protein TypA
MLOALDAC_00384 6.7e-24 S Family of unknown function (DUF5325)
MLOALDAC_00385 4.1e-38 ylaE
MLOALDAC_00386 2.8e-13 sigC S Putative zinc-finger
MLOALDAC_00387 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MLOALDAC_00388 4.4e-82 ykzC S Acetyltransferase (GNAT) family
MLOALDAC_00389 9.4e-152 suhB 3.1.3.25 G Inositol monophosphatase
MLOALDAC_00390 6.3e-24 ykzI
MLOALDAC_00391 4.9e-119 yktB S Belongs to the UPF0637 family
MLOALDAC_00392 1.6e-42 yktA S Belongs to the UPF0223 family
MLOALDAC_00393 4.1e-278 speA 4.1.1.19 E Arginine
MLOALDAC_00394 2.7e-138 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
MLOALDAC_00395 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MLOALDAC_00396 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLOALDAC_00397 3.4e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLOALDAC_00398 3.2e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLOALDAC_00399 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLOALDAC_00400 7.9e-210 V Beta-lactamase
MLOALDAC_00401 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
MLOALDAC_00402 0.0 Q Polyketide synthase of type I
MLOALDAC_00403 0.0 Q Polyketide synthase of type I
MLOALDAC_00404 0.0 Q Polyketide synthase of type I
MLOALDAC_00405 0.0 Q Polyketide synthase of type I
MLOALDAC_00406 0.0 Q polyketide synthase
MLOALDAC_00407 0.0 Q Polyketide synthase of type I
MLOALDAC_00408 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLOALDAC_00409 6.5e-103 recN L Putative cell-wall binding lipoprotein
MLOALDAC_00411 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MLOALDAC_00412 3.9e-147 ykrA S hydrolases of the HAD superfamily
MLOALDAC_00413 8.2e-31 ykzG S Belongs to the UPF0356 family
MLOALDAC_00414 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MLOALDAC_00415 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MLOALDAC_00416 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
MLOALDAC_00417 2e-149 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MLOALDAC_00418 3.7e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MLOALDAC_00419 2.1e-45 abrB K of stationary sporulation gene expression
MLOALDAC_00420 6.9e-184 mreB D Rod-share determining protein MreBH
MLOALDAC_00421 7.2e-12 S Uncharacterized protein YkpC
MLOALDAC_00422 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MLOALDAC_00423 5.3e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLOALDAC_00424 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLOALDAC_00425 9.8e-37 ykoA
MLOALDAC_00426 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLOALDAC_00427 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MLOALDAC_00428 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MLOALDAC_00429 4.1e-133 fruR K Transcriptional regulator
MLOALDAC_00430 2.4e-212 yknZ V ABC transporter (permease)
MLOALDAC_00431 6.1e-123 macB V ABC transporter, ATP-binding protein
MLOALDAC_00432 2.6e-171 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLOALDAC_00433 1.3e-104 yknW S Yip1 domain
MLOALDAC_00434 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MLOALDAC_00435 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MLOALDAC_00436 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MLOALDAC_00437 3.2e-242 moeA 2.10.1.1 H molybdopterin
MLOALDAC_00438 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLOALDAC_00439 5.7e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MLOALDAC_00440 4.3e-162 yknT
MLOALDAC_00441 1.5e-98 rok K Repressor of ComK
MLOALDAC_00442 5.5e-80 ykuV CO thiol-disulfide
MLOALDAC_00443 4.9e-140 ykuT M Mechanosensitive ion channel
MLOALDAC_00444 4.8e-38 ykuS S Belongs to the UPF0180 family
MLOALDAC_00445 5.3e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MLOALDAC_00446 1.7e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MLOALDAC_00447 1e-78 fld C Flavodoxin
MLOALDAC_00448 1.9e-169 ykuO
MLOALDAC_00449 1.3e-89 fld C Flavodoxin
MLOALDAC_00450 2.3e-167 ccpC K Transcriptional regulator
MLOALDAC_00451 2.3e-75 ykuL S CBS domain
MLOALDAC_00452 2.5e-26 ykzF S Antirepressor AbbA
MLOALDAC_00453 1.7e-93 ykuK S Ribonuclease H-like
MLOALDAC_00454 3.9e-37 ykuJ S protein conserved in bacteria
MLOALDAC_00455 1.5e-233 ykuI T Diguanylate phosphodiesterase
MLOALDAC_00456 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLOALDAC_00457 6.1e-157 ykuE S Metallophosphoesterase
MLOALDAC_00458 1.3e-87 ykuD S protein conserved in bacteria
MLOALDAC_00459 1.7e-240 ykuC EGP Major facilitator Superfamily
MLOALDAC_00460 1.4e-83 ykyB S YkyB-like protein
MLOALDAC_00461 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
MLOALDAC_00462 2.3e-09
MLOALDAC_00463 3.9e-215 patA 2.6.1.1 E Aminotransferase
MLOALDAC_00464 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
MLOALDAC_00465 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MLOALDAC_00466 2.4e-112 ykwD J protein with SCP PR1 domains
MLOALDAC_00467 4.3e-49
MLOALDAC_00468 2.8e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MLOALDAC_00469 1.9e-262 mcpC NT chemotaxis protein
MLOALDAC_00470 7.2e-189 splB 4.1.99.14 L Spore photoproduct lyase
MLOALDAC_00471 6.1e-38 splA S Transcriptional regulator
MLOALDAC_00472 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLOALDAC_00473 2.1e-39 ptsH G phosphocarrier protein HPr
MLOALDAC_00474 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLOALDAC_00475 5.1e-156 glcT K antiterminator
MLOALDAC_00476 3.9e-176 ykvZ 5.1.1.1 K Transcriptional regulator
MLOALDAC_00478 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MLOALDAC_00479 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MLOALDAC_00480 2.7e-88 stoA CO thiol-disulfide
MLOALDAC_00481 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLOALDAC_00482 6.3e-111 ykvT 3.5.1.28 M Cell Wall Hydrolase
MLOALDAC_00483 2.3e-27
MLOALDAC_00484 7.8e-25 ykvS S protein conserved in bacteria
MLOALDAC_00485 3.5e-45 ykvR S Protein of unknown function (DUF3219)
MLOALDAC_00487 6.9e-162 G Glycosyl hydrolases family 18
MLOALDAC_00488 3e-34 3.5.1.104 M LysM domain
MLOALDAC_00489 2.1e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
MLOALDAC_00490 1.4e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLOALDAC_00491 1.6e-132 IQ Enoyl-(Acyl carrier protein) reductase
MLOALDAC_00492 6.4e-60 ykvN K HxlR-like helix-turn-helix
MLOALDAC_00494 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLOALDAC_00495 1.9e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MLOALDAC_00496 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MLOALDAC_00497 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MLOALDAC_00498 1.2e-189
MLOALDAC_00499 1.4e-184 ykvI S membrane
MLOALDAC_00500 0.0 clpE O Belongs to the ClpA ClpB family
MLOALDAC_00501 1.1e-136 motA N flagellar motor
MLOALDAC_00502 2.7e-127 motB N Flagellar motor protein
MLOALDAC_00503 1.5e-77 ykvE K transcriptional
MLOALDAC_00504 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MLOALDAC_00505 3.4e-10 S Spo0E like sporulation regulatory protein
MLOALDAC_00506 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MLOALDAC_00507 6.1e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MLOALDAC_00508 3.7e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MLOALDAC_00509 2.3e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MLOALDAC_00510 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
MLOALDAC_00511 2.9e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLOALDAC_00512 3.5e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MLOALDAC_00513 4.4e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MLOALDAC_00515 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLOALDAC_00516 0.0 kinE 2.7.13.3 T Histidine kinase
MLOALDAC_00517 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MLOALDAC_00518 7.9e-24 ykzE
MLOALDAC_00519 2.9e-114 ydfR S Protein of unknown function (DUF421)
MLOALDAC_00520 1.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
MLOALDAC_00521 4.1e-156 htpX O Belongs to the peptidase M48B family
MLOALDAC_00522 7.3e-124 ykrK S Domain of unknown function (DUF1836)
MLOALDAC_00523 2.5e-26 sspD S small acid-soluble spore protein
MLOALDAC_00524 3.1e-119 rsgI S Anti-sigma factor N-terminus
MLOALDAC_00525 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLOALDAC_00526 9.2e-136 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MLOALDAC_00527 4.5e-100 ykoX S membrane-associated protein
MLOALDAC_00528 4.2e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MLOALDAC_00529 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MLOALDAC_00530 2.2e-99 ykoP G polysaccharide deacetylase
MLOALDAC_00531 1.1e-80 ykoM K transcriptional
MLOALDAC_00532 3.1e-26 ykoL
MLOALDAC_00533 1.9e-16
MLOALDAC_00534 5.4e-53 tnrA K transcriptional
MLOALDAC_00535 2.2e-238 mgtE P Acts as a magnesium transporter
MLOALDAC_00537 1e-245 ydhD M Glycosyl hydrolase
MLOALDAC_00538 3.4e-98 ykoE S ABC-type cobalt transport system, permease component
MLOALDAC_00539 1.7e-304 P ABC transporter, ATP-binding protein
MLOALDAC_00540 3.5e-132 ykoC P Cobalt transport protein
MLOALDAC_00541 5.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLOALDAC_00542 1e-176 isp O Belongs to the peptidase S8 family
MLOALDAC_00543 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MLOALDAC_00544 1.6e-120 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MLOALDAC_00545 3.6e-216 hcaT 1.5.1.2 EGP Major facilitator Superfamily
MLOALDAC_00546 1.8e-129 M PFAM Collagen triple helix repeat (20 copies)
MLOALDAC_00547 3.1e-217 M Glycosyl transferase family 2
MLOALDAC_00549 8.9e-59 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MLOALDAC_00550 4.2e-71 ohrB O Organic hydroperoxide resistance protein
MLOALDAC_00551 2.2e-85 ohrR K COG1846 Transcriptional regulators
MLOALDAC_00552 1.3e-70 ohrA O Organic hydroperoxide resistance protein
MLOALDAC_00553 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLOALDAC_00554 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLOALDAC_00555 2.3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MLOALDAC_00556 3.4e-49 ykkD P Multidrug resistance protein
MLOALDAC_00557 9.4e-53 ykkC P Multidrug resistance protein
MLOALDAC_00558 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLOALDAC_00559 4.1e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MLOALDAC_00560 1e-159 ykgA E Amidinotransferase
MLOALDAC_00561 1.1e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
MLOALDAC_00562 4.3e-183 ykfD E Belongs to the ABC transporter superfamily
MLOALDAC_00563 1.6e-171 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLOALDAC_00564 1e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MLOALDAC_00565 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MLOALDAC_00566 0.0 dppE E ABC transporter substrate-binding protein
MLOALDAC_00567 1.3e-190 dppD P Belongs to the ABC transporter superfamily
MLOALDAC_00568 8.5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLOALDAC_00569 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLOALDAC_00570 6.5e-156 dppA E D-aminopeptidase
MLOALDAC_00572 1e-287 yubD P Major Facilitator Superfamily
MLOALDAC_00573 3.8e-206 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLOALDAC_00575 3.4e-180 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLOALDAC_00576 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLOALDAC_00577 1.4e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MLOALDAC_00578 4.2e-242 steT E amino acid
MLOALDAC_00579 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MLOALDAC_00580 2e-175 pit P phosphate transporter
MLOALDAC_00581 2.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MLOALDAC_00582 8.7e-23 spoIISB S Stage II sporulation protein SB
MLOALDAC_00583 3.9e-167 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLOALDAC_00584 1.3e-38 xhlB S SPP1 phage holin
MLOALDAC_00585 8.7e-38 xhlA S Haemolysin XhlA
MLOALDAC_00586 2.5e-138 xepA
MLOALDAC_00587 1.7e-30 xkdX
MLOALDAC_00589 1.4e-90
MLOALDAC_00590 4.2e-27
MLOALDAC_00591 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MLOALDAC_00592 5.1e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MLOALDAC_00593 2.1e-57 xkdS S Protein of unknown function (DUF2634)
MLOALDAC_00594 7.2e-32 xkdR S Protein of unknown function (DUF2577)
MLOALDAC_00595 8e-161 xkdQ 3.2.1.96 G NLP P60 protein
MLOALDAC_00596 3.9e-111 xkdP S Lysin motif
MLOALDAC_00597 3.7e-188 xkdO L Transglycosylase SLT domain
MLOALDAC_00598 3.4e-19
MLOALDAC_00599 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
MLOALDAC_00600 2e-74 xkdM S Phage tail tube protein
MLOALDAC_00601 1e-225 xkdK S Phage tail sheath C-terminal domain
MLOALDAC_00602 8.2e-15
MLOALDAC_00603 4.9e-57 xkdJ
MLOALDAC_00604 3.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
MLOALDAC_00605 4.2e-43 yqbH S Domain of unknown function (DUF3599)
MLOALDAC_00606 1.7e-45 yqbG S Protein of unknown function (DUF3199)
MLOALDAC_00607 1e-157 xkdG S Phage capsid family
MLOALDAC_00608 5.7e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
MLOALDAC_00609 7.9e-242 yqbA S portal protein
MLOALDAC_00610 7.9e-209 xtmB S phage terminase, large subunit
MLOALDAC_00611 6.8e-110 xtmA L phage terminase small subunit
MLOALDAC_00612 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLOALDAC_00613 2e-10 yqaO S Phage-like element PBSX protein XtrA
MLOALDAC_00616 1e-153 xkdC L Bacterial dnaA protein
MLOALDAC_00618 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
MLOALDAC_00619 2.5e-109 xkdA E IrrE N-terminal-like domain
MLOALDAC_00620 7.9e-08 xkdA E IrrE N-terminal-like domain
MLOALDAC_00621 3.6e-111 yjqB S phage-related replication protein
MLOALDAC_00622 4.7e-61 yjqA S Bacterial PH domain
MLOALDAC_00623 5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MLOALDAC_00625 4.9e-215 S response regulator aspartate phosphatase
MLOALDAC_00626 2.1e-79 yjoA S DinB family
MLOALDAC_00627 3.9e-131 MA20_18170 S membrane transporter protein
MLOALDAC_00628 2.2e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MLOALDAC_00629 1.6e-282 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MLOALDAC_00630 3.4e-183 exuR K transcriptional
MLOALDAC_00631 1.1e-253 yjmB G symporter YjmB
MLOALDAC_00632 4.3e-277 uxaC 5.3.1.12 G glucuronate isomerase
MLOALDAC_00633 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
MLOALDAC_00634 7e-66 yjlC S Protein of unknown function (DUF1641)
MLOALDAC_00635 1.5e-91 yjlB S Cupin domain
MLOALDAC_00636 1e-176 yjlA EG Putative multidrug resistance efflux transporter
MLOALDAC_00637 4.5e-132 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
MLOALDAC_00638 7e-123 ybbM S transport system, permease component
MLOALDAC_00639 9.5e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MLOALDAC_00640 6.8e-29
MLOALDAC_00641 3e-223 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLOALDAC_00642 9.4e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MLOALDAC_00643 4.3e-92 yjgD S Protein of unknown function (DUF1641)
MLOALDAC_00644 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
MLOALDAC_00645 2.4e-101 yjgB S Domain of unknown function (DUF4309)
MLOALDAC_00646 5.9e-70 T PhoQ Sensor
MLOALDAC_00647 7.5e-22 yjfB S Putative motility protein
MLOALDAC_00649 4e-105 yhiD S MgtC SapB transporter
MLOALDAC_00651 1.5e-145 N Kelch motif
MLOALDAC_00652 5.8e-126 5.4.2.6 S Haloacid dehalogenase-like hydrolase
MLOALDAC_00653 5.7e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
MLOALDAC_00654 1.2e-282 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
MLOALDAC_00655 3.4e-49 lacF 2.7.1.207 G phosphotransferase system
MLOALDAC_00656 2.4e-311 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLOALDAC_00657 8.4e-218 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLOALDAC_00658 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MLOALDAC_00659 3.6e-290 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MLOALDAC_00660 1.4e-222 ganA 3.2.1.89 G arabinogalactan
MLOALDAC_00661 2.3e-81 napB K helix_turn_helix multiple antibiotic resistance protein
MLOALDAC_00662 2.2e-252 yfjF EGP Belongs to the major facilitator superfamily
MLOALDAC_00663 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
MLOALDAC_00664 6.5e-165 bla 3.5.2.6 V beta-lactamase
MLOALDAC_00665 3.5e-59 E Glyoxalase-like domain
MLOALDAC_00667 3e-73 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MLOALDAC_00668 1.2e-49 FG Scavenger mRNA decapping enzyme C-term binding
MLOALDAC_00669 2.4e-12
MLOALDAC_00670 2.8e-10 S Uncharacterised protein family (UPF0715)
MLOALDAC_00671 3.6e-131
MLOALDAC_00674 2.1e-258 yobL S Bacterial EndoU nuclease
MLOALDAC_00675 6.9e-23
MLOALDAC_00676 3.1e-84
MLOALDAC_00677 4.3e-30
MLOALDAC_00678 6.4e-13
MLOALDAC_00679 1.5e-07
MLOALDAC_00680 1.3e-41 O Preprotein translocase subunit SecB
MLOALDAC_00682 0.0 yobL S Bacterial EndoU nuclease
MLOALDAC_00683 1.3e-54
MLOALDAC_00685 2.6e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLOALDAC_00686 5.4e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLOALDAC_00687 6.1e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
MLOALDAC_00688 7.8e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MLOALDAC_00689 1.9e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLOALDAC_00690 2.7e-35 K SpoVT / AbrB like domain
MLOALDAC_00691 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
MLOALDAC_00692 5.2e-125 S ABC-2 type transporter
MLOALDAC_00693 6.8e-136 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MLOALDAC_00694 5.1e-35
MLOALDAC_00695 0.0 yjcD 3.6.4.12 L DNA helicase
MLOALDAC_00696 3.8e-38 spoVIF S Stage VI sporulation protein F
MLOALDAC_00700 5.6e-56 yjcA S Protein of unknown function (DUF1360)
MLOALDAC_00701 1.1e-54 cotV S Spore Coat Protein X and V domain
MLOALDAC_00702 2.3e-21 cotW
MLOALDAC_00703 3.9e-71 cotX S Spore Coat Protein X and V domain
MLOALDAC_00704 8.1e-90 cotY S Spore coat protein Z
MLOALDAC_00705 2.6e-79 cotZ S Spore coat protein
MLOALDAC_00706 3e-89 yjbX S Spore coat protein
MLOALDAC_00707 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MLOALDAC_00708 2.9e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MLOALDAC_00709 3.5e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MLOALDAC_00710 2.9e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MLOALDAC_00711 1.4e-30 thiS H Thiamine biosynthesis
MLOALDAC_00712 2.5e-211 thiO 1.4.3.19 E Glycine oxidase
MLOALDAC_00713 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MLOALDAC_00714 5.8e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MLOALDAC_00715 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MLOALDAC_00716 1.7e-142 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MLOALDAC_00717 4.1e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLOALDAC_00718 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLOALDAC_00719 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
MLOALDAC_00720 1.6e-61 yjbL S Belongs to the UPF0738 family
MLOALDAC_00721 1.4e-96 yjbK S protein conserved in bacteria
MLOALDAC_00722 1.1e-116 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLOALDAC_00723 4.8e-72 yjbI S Bacterial-like globin
MLOALDAC_00724 6.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MLOALDAC_00725 5.8e-19
MLOALDAC_00726 0.0 pepF E oligoendopeptidase F
MLOALDAC_00727 8.1e-221 yjbF S Competence protein
MLOALDAC_00728 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLOALDAC_00729 3.6e-109 yjbE P Integral membrane protein TerC family
MLOALDAC_00730 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MLOALDAC_00731 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLOALDAC_00732 8e-232 S Putative glycosyl hydrolase domain
MLOALDAC_00733 2.5e-172 oppF E Belongs to the ABC transporter superfamily
MLOALDAC_00734 2.7e-202 oppD P Belongs to the ABC transporter superfamily
MLOALDAC_00735 5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLOALDAC_00736 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLOALDAC_00737 0.0 oppA E ABC transporter substrate-binding protein
MLOALDAC_00738 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MLOALDAC_00739 5.5e-146 yjbA S Belongs to the UPF0736 family
MLOALDAC_00740 2.7e-140 EGP Transmembrane secretion effector
MLOALDAC_00741 1.7e-86 2.1.1.265 H Tellurite resistance protein TehB
MLOALDAC_00742 6.1e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLOALDAC_00743 5.3e-170 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLOALDAC_00744 3.1e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MLOALDAC_00745 5e-187 appF E Belongs to the ABC transporter superfamily
MLOALDAC_00746 2.2e-182 appD P Belongs to the ABC transporter superfamily
MLOALDAC_00747 2.3e-147 yjaZ O Zn-dependent protease
MLOALDAC_00748 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLOALDAC_00749 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLOALDAC_00750 5.9e-32 yjzB
MLOALDAC_00751 4.3e-26 comZ S ComZ
MLOALDAC_00752 7.2e-166 med S Transcriptional activator protein med
MLOALDAC_00753 1.5e-106 yjaV
MLOALDAC_00754 4.4e-140 yjaU I carboxylic ester hydrolase activity
MLOALDAC_00755 1.5e-23 yjzD S Protein of unknown function (DUF2929)
MLOALDAC_00756 1.2e-27 yjzC S YjzC-like protein
MLOALDAC_00757 2.1e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLOALDAC_00758 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MLOALDAC_00759 1.2e-202 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MLOALDAC_00760 8.9e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MLOALDAC_00761 2.6e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
MLOALDAC_00762 6.1e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MLOALDAC_00763 6.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MLOALDAC_00764 1.2e-89 norB G Major Facilitator Superfamily
MLOALDAC_00765 2.1e-196 yitY C D-arabinono-1,4-lactone oxidase
MLOALDAC_00766 1.1e-44 yitY C D-arabinono-1,4-lactone oxidase
MLOALDAC_00767 4.1e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MLOALDAC_00768 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MLOALDAC_00769 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MLOALDAC_00770 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MLOALDAC_00771 3.5e-07
MLOALDAC_00772 4.4e-26 S Protein of unknown function (DUF3813)
MLOALDAC_00773 2.9e-81 ipi S Intracellular proteinase inhibitor
MLOALDAC_00774 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MLOALDAC_00775 4.9e-159 yitS S protein conserved in bacteria
MLOALDAC_00777 1.1e-244 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MLOALDAC_00778 1.5e-233 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MLOALDAC_00779 4.1e-173 yufN S ABC transporter substrate-binding protein PnrA-like
MLOALDAC_00780 5.3e-161 cvfB S protein conserved in bacteria
MLOALDAC_00781 6.6e-55 yajQ S Belongs to the UPF0234 family
MLOALDAC_00782 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MLOALDAC_00783 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
MLOALDAC_00784 9.5e-59 mcbG S Pentapeptide repeats (9 copies)
MLOALDAC_00785 5.7e-192 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLOALDAC_00786 1.2e-74 argO S Lysine exporter protein LysE YggA
MLOALDAC_00787 3.7e-90 yisT S DinB family
MLOALDAC_00788 1e-159 yisR K Transcriptional regulator
MLOALDAC_00789 1.5e-245 yisQ V Mate efflux family protein
MLOALDAC_00790 7.4e-135 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MLOALDAC_00791 0.0 asnO 6.3.5.4 E Asparagine synthase
MLOALDAC_00792 5.3e-98 yisN S Protein of unknown function (DUF2777)
MLOALDAC_00793 1.1e-59 yisL S UPF0344 protein
MLOALDAC_00794 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MLOALDAC_00795 5e-07 yisI S Spo0E like sporulation regulatory protein
MLOALDAC_00796 8.4e-34 gerPA S Spore germination protein
MLOALDAC_00797 6.2e-35 gerPB S cell differentiation
MLOALDAC_00798 9.1e-62 gerPC S Spore germination protein
MLOALDAC_00799 3.1e-23 gerPD S Spore germination protein
MLOALDAC_00800 1.2e-62 gerPE S Spore germination protein GerPE
MLOALDAC_00801 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
MLOALDAC_00802 1.3e-50 yisB V COG1403 Restriction endonuclease
MLOALDAC_00803 0.0 sbcC L COG0419 ATPase involved in DNA repair
MLOALDAC_00804 3.3e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MLOALDAC_00805 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MLOALDAC_00806 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MLOALDAC_00808 1.5e-50 ydfS S Protein of unknown function (DUF421)
MLOALDAC_00809 9.7e-94 yhjR S Rubrerythrin
MLOALDAC_00810 7.6e-109 K QacR-like protein, C-terminal region
MLOALDAC_00811 6.2e-208 blt EGP Major facilitator Superfamily
MLOALDAC_00812 2.8e-181 abrB S membrane
MLOALDAC_00813 9.7e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MLOALDAC_00814 8.6e-276 yhjG CH FAD binding domain
MLOALDAC_00816 1.6e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MLOALDAC_00817 1.8e-110 yhjE S SNARE associated Golgi protein
MLOALDAC_00818 3.2e-59 yhjD
MLOALDAC_00819 1.4e-27 yhjC S Protein of unknown function (DUF3311)
MLOALDAC_00820 5e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLOALDAC_00821 3.3e-47 S Belongs to the UPF0145 family
MLOALDAC_00822 1.6e-42 yhjA S Excalibur calcium-binding domain
MLOALDAC_00823 4.2e-127 yrpD S Domain of unknown function, YrpD
MLOALDAC_00824 7e-92 mepB S MepB protein
MLOALDAC_00825 8.2e-66 frataxin S Domain of unknown function (DU1801)
MLOALDAC_00826 2.1e-66 frataxin S Domain of unknown function (DU1801)
MLOALDAC_00827 1.9e-109 comK K Competence transcription factor
MLOALDAC_00828 1.3e-32 yhzC S IDEAL
MLOALDAC_00829 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLOALDAC_00830 9.7e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MLOALDAC_00831 9.1e-197 hemAT NT chemotaxis protein
MLOALDAC_00832 9.3e-90 bioY S BioY family
MLOALDAC_00833 4.3e-280 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MLOALDAC_00834 5.5e-203 vraB 2.3.1.9 I Belongs to the thiolase family
MLOALDAC_00835 2.6e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MLOALDAC_00836 1.2e-155 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MLOALDAC_00837 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MLOALDAC_00838 1.7e-237 yhfN 3.4.24.84 O Peptidase M48
MLOALDAC_00839 1.9e-65 yhfM
MLOALDAC_00840 3.4e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MLOALDAC_00841 3.1e-113 yhfK GM NmrA-like family
MLOALDAC_00842 2.3e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
MLOALDAC_00843 9.9e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MLOALDAC_00844 7.9e-11 yhfH S YhfH-like protein
MLOALDAC_00845 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLOALDAC_00846 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MLOALDAC_00848 7.4e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLOALDAC_00849 3.2e-277 yhgE S YhgE Pip N-terminal domain protein
MLOALDAC_00850 3.5e-100 yhgD K Transcriptional regulator
MLOALDAC_00851 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MLOALDAC_00852 2.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MLOALDAC_00853 8.6e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MLOALDAC_00854 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLOALDAC_00855 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MLOALDAC_00856 1.1e-243 yhfA C membrane
MLOALDAC_00857 2.5e-225 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MLOALDAC_00858 2.8e-123 ecsC S EcsC protein family
MLOALDAC_00859 9.5e-220 ecsB U ABC transporter
MLOALDAC_00860 1.1e-135 ecsA V transporter (ATP-binding protein)
MLOALDAC_00861 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MLOALDAC_00862 1.2e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MLOALDAC_00863 6.4e-77 trpP S Tryptophan transporter TrpP
MLOALDAC_00864 2e-17
MLOALDAC_00865 2.4e-38 yhaH S YtxH-like protein
MLOALDAC_00866 8.6e-113 hpr K Negative regulator of protease production and sporulation
MLOALDAC_00867 9.9e-55 yhaI S Protein of unknown function (DUF1878)
MLOALDAC_00868 9.1e-95 yhaK S Putative zincin peptidase
MLOALDAC_00869 1.7e-122 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MLOALDAC_00870 3.5e-129 IQ reductase
MLOALDAC_00871 5.9e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLOALDAC_00874 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MLOALDAC_00875 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
MLOALDAC_00876 2.6e-163 K LysR substrate binding domain
MLOALDAC_00877 8.4e-51 S GlpM protein
MLOALDAC_00878 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MLOALDAC_00879 1e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MLOALDAC_00880 1.9e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MLOALDAC_00881 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLOALDAC_00882 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLOALDAC_00883 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLOALDAC_00884 2.4e-25 yqzJ
MLOALDAC_00885 3.5e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLOALDAC_00886 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MLOALDAC_00887 1.3e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MLOALDAC_00888 5.5e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MLOALDAC_00890 1.4e-95 yqjB S protein conserved in bacteria
MLOALDAC_00891 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
MLOALDAC_00892 2.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLOALDAC_00893 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
MLOALDAC_00894 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
MLOALDAC_00895 1e-75 yqiW S Belongs to the UPF0403 family
MLOALDAC_00896 7.7e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLOALDAC_00897 2.4e-202 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLOALDAC_00898 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLOALDAC_00899 3e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLOALDAC_00900 2.7e-266 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLOALDAC_00901 3.7e-207 buk 2.7.2.7 C Belongs to the acetokinase family
MLOALDAC_00902 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLOALDAC_00903 6.1e-152 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MLOALDAC_00904 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MLOALDAC_00905 3.2e-34 yqzF S Protein of unknown function (DUF2627)
MLOALDAC_00906 1.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MLOALDAC_00907 7.5e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MLOALDAC_00908 4.1e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MLOALDAC_00909 1.2e-205 mmgC I acyl-CoA dehydrogenase
MLOALDAC_00910 7.4e-155 hbdA 1.1.1.157 I Dehydrogenase
MLOALDAC_00911 6.3e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
MLOALDAC_00912 3.3e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLOALDAC_00913 1.4e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MLOALDAC_00914 2.5e-17
MLOALDAC_00915 2.6e-101 ytaF P Probably functions as a manganese efflux pump
MLOALDAC_00916 4.4e-112 K Protein of unknown function (DUF1232)
MLOALDAC_00918 3.2e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MLOALDAC_00921 5.2e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLOALDAC_00922 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MLOALDAC_00923 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
MLOALDAC_00924 1.2e-305 recN L May be involved in recombinational repair of damaged DNA
MLOALDAC_00925 3.9e-78 argR K Regulates arginine biosynthesis genes
MLOALDAC_00926 9.6e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MLOALDAC_00927 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLOALDAC_00928 2.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MLOALDAC_00929 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLOALDAC_00930 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MLOALDAC_00931 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLOALDAC_00932 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLOALDAC_00933 8.1e-67 yqhY S protein conserved in bacteria
MLOALDAC_00934 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MLOALDAC_00935 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MLOALDAC_00936 2.5e-62 spoIIIAH S SpoIIIAH-like protein
MLOALDAC_00937 7.7e-118 spoIIIAG S stage III sporulation protein AG
MLOALDAC_00938 2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MLOALDAC_00939 1.1e-199 spoIIIAE S stage III sporulation protein AE
MLOALDAC_00940 2.5e-41 spoIIIAD S Stage III sporulation protein AD
MLOALDAC_00941 7.6e-29 spoIIIAC S stage III sporulation protein AC
MLOALDAC_00942 1.7e-85 spoIIIAB S Stage III sporulation protein
MLOALDAC_00943 4.2e-172 spoIIIAA S stage III sporulation protein AA
MLOALDAC_00944 1.8e-36 yqhV S Protein of unknown function (DUF2619)
MLOALDAC_00945 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLOALDAC_00946 1.1e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MLOALDAC_00947 3.7e-88 yqhR S Conserved membrane protein YqhR
MLOALDAC_00948 8e-174 yqhQ S Protein of unknown function (DUF1385)
MLOALDAC_00949 1.7e-61 yqhP
MLOALDAC_00950 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
MLOALDAC_00951 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MLOALDAC_00952 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MLOALDAC_00953 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
MLOALDAC_00954 1.5e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLOALDAC_00955 3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLOALDAC_00956 2.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MLOALDAC_00957 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLOALDAC_00958 8.4e-153 yqhG S Bacterial protein YqhG of unknown function
MLOALDAC_00959 5.2e-23 sinI S Anti-repressor SinI
MLOALDAC_00960 7.8e-55 sinR K transcriptional
MLOALDAC_00961 3.3e-141 tasA S Cell division protein FtsN
MLOALDAC_00962 1e-70 sipW 3.4.21.89 U Signal peptidase
MLOALDAC_00963 1.6e-120 yqxM
MLOALDAC_00964 1.3e-54 yqzG S Protein of unknown function (DUF3889)
MLOALDAC_00965 2.3e-26 yqzE S YqzE-like protein
MLOALDAC_00966 2.9e-63 S ComG operon protein 7
MLOALDAC_00967 3e-66 comGF U Putative Competence protein ComGF
MLOALDAC_00968 2.6e-20 comGE
MLOALDAC_00969 1.8e-72 gspH NU Tfp pilus assembly protein FimT
MLOALDAC_00970 8.9e-50 comGC U Required for transformation and DNA binding
MLOALDAC_00971 1.2e-183 comGB NU COG1459 Type II secretory pathway, component PulF
MLOALDAC_00972 6.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MLOALDAC_00973 4.1e-186 corA P Mg2 transporter protein
MLOALDAC_00974 7.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLOALDAC_00975 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLOALDAC_00977 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
MLOALDAC_00978 1.5e-36 yqgY S Protein of unknown function (DUF2626)
MLOALDAC_00979 8.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MLOALDAC_00980 5.4e-20 yqgW S Protein of unknown function (DUF2759)
MLOALDAC_00981 6.9e-50 yqgV S Thiamine-binding protein
MLOALDAC_00982 1e-198 yqgU
MLOALDAC_00983 6.7e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MLOALDAC_00984 2.2e-179 glcK 2.7.1.2 G Glucokinase
MLOALDAC_00985 1.8e-213 nhaC C Na H antiporter
MLOALDAC_00986 4e-07 yqgO
MLOALDAC_00987 4.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MLOALDAC_00988 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MLOALDAC_00989 1.2e-50 yqzD
MLOALDAC_00990 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLOALDAC_00991 1.1e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLOALDAC_00992 8.6e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MLOALDAC_00993 2.4e-156 pstA P Phosphate transport system permease
MLOALDAC_00994 5.2e-154 pstC P probably responsible for the translocation of the substrate across the membrane
MLOALDAC_00995 1.7e-157 pstS P Phosphate
MLOALDAC_00996 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MLOALDAC_00997 2e-228 yqgE EGP Major facilitator superfamily
MLOALDAC_00998 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MLOALDAC_00999 6e-77 yqgC S protein conserved in bacteria
MLOALDAC_01000 8.7e-131 yqgB S Protein of unknown function (DUF1189)
MLOALDAC_01001 8.2e-48 yqfZ M LysM domain
MLOALDAC_01002 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MLOALDAC_01003 2.3e-52 yqfX S membrane
MLOALDAC_01004 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MLOALDAC_01005 2.9e-72 zur P Belongs to the Fur family
MLOALDAC_01006 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MLOALDAC_01007 7.9e-36 yqfT S Protein of unknown function (DUF2624)
MLOALDAC_01008 4.4e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MLOALDAC_01009 3e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MLOALDAC_01010 3.7e-46 yqfQ S YqfQ-like protein
MLOALDAC_01011 2.5e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MLOALDAC_01012 4.3e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MLOALDAC_01013 8.4e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
MLOALDAC_01014 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
MLOALDAC_01015 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MLOALDAC_01016 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MLOALDAC_01017 6.1e-88 yaiI S Belongs to the UPF0178 family
MLOALDAC_01018 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MLOALDAC_01019 4.5e-112 ccpN K CBS domain
MLOALDAC_01020 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MLOALDAC_01021 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MLOALDAC_01022 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
MLOALDAC_01023 1.8e-16 S YqzL-like protein
MLOALDAC_01024 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLOALDAC_01025 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MLOALDAC_01026 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MLOALDAC_01027 2.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLOALDAC_01028 0.0 yqfF S membrane-associated HD superfamily hydrolase
MLOALDAC_01029 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
MLOALDAC_01030 4.4e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MLOALDAC_01031 9.3e-46 yqfC S sporulation protein YqfC
MLOALDAC_01032 3.4e-55 yqfB
MLOALDAC_01033 1.6e-121 yqfA S UPF0365 protein
MLOALDAC_01034 2.8e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MLOALDAC_01035 1.2e-68 yqeY S Yqey-like protein
MLOALDAC_01036 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MLOALDAC_01037 1.6e-158 yqeW P COG1283 Na phosphate symporter
MLOALDAC_01038 1e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MLOALDAC_01039 4.4e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MLOALDAC_01040 4.6e-174 prmA J Methylates ribosomal protein L11
MLOALDAC_01041 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MLOALDAC_01042 0.0 dnaK O Heat shock 70 kDa protein
MLOALDAC_01043 7.9e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLOALDAC_01044 8.9e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MLOALDAC_01045 1.4e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
MLOALDAC_01046 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MLOALDAC_01047 7.9e-52 yqxA S Protein of unknown function (DUF3679)
MLOALDAC_01048 4.1e-220 spoIIP M stage II sporulation protein P
MLOALDAC_01049 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MLOALDAC_01050 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
MLOALDAC_01051 1.9e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
MLOALDAC_01052 0.0 comEC S Competence protein ComEC
MLOALDAC_01053 8e-105 comEB 3.5.4.12 F ComE operon protein 2
MLOALDAC_01054 2.8e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MLOALDAC_01055 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLOALDAC_01056 8.4e-139 yqeM Q Methyltransferase
MLOALDAC_01057 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MLOALDAC_01058 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MLOALDAC_01059 1.1e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLOALDAC_01060 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MLOALDAC_01061 2.1e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLOALDAC_01062 3.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MLOALDAC_01063 2e-94 yqeG S hydrolase of the HAD superfamily
MLOALDAC_01065 1.1e-138 yqeF E GDSL-like Lipase/Acylhydrolase
MLOALDAC_01066 4e-141 3.5.1.104 G Polysaccharide deacetylase
MLOALDAC_01067 4.2e-107 yqeD S SNARE associated Golgi protein
MLOALDAC_01068 8.4e-26 2.3.1.57 K Acetyltransferase (GNAT) domain
MLOALDAC_01069 6.5e-216 EGP Major facilitator Superfamily
MLOALDAC_01070 4e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLOALDAC_01071 1.9e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
MLOALDAC_01072 4.2e-92 K Transcriptional regulator PadR-like family
MLOALDAC_01073 2.4e-148 ydeE K AraC family transcriptional regulator
MLOALDAC_01074 1.1e-98 adk 2.7.4.3 F adenylate kinase activity
MLOALDAC_01075 7.7e-32 yyaR K acetyltransferase
MLOALDAC_01076 4.8e-32 tetL EGP Major facilitator Superfamily
MLOALDAC_01077 1.8e-79 yyaR K Acetyltransferase (GNAT) domain
MLOALDAC_01078 8.9e-92 yrdA S DinB family
MLOALDAC_01080 2.7e-146 S hydrolase
MLOALDAC_01081 1e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
MLOALDAC_01082 4.5e-129 glvR K Helix-turn-helix domain, rpiR family
MLOALDAC_01083 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MLOALDAC_01084 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MLOALDAC_01085 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MLOALDAC_01086 1.1e-183 romA S Beta-lactamase superfamily domain
MLOALDAC_01087 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MLOALDAC_01088 1.1e-164 yybE K Transcriptional regulator
MLOALDAC_01089 1.1e-212 ynfM EGP Major facilitator Superfamily
MLOALDAC_01090 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MLOALDAC_01091 1.7e-99 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MLOALDAC_01092 1.1e-92 yrhH Q methyltransferase
MLOALDAC_01094 8e-143 focA P Formate nitrite
MLOALDAC_01095 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
MLOALDAC_01096 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
MLOALDAC_01097 7e-81 yrhD S Protein of unknown function (DUF1641)
MLOALDAC_01098 4.6e-35 yrhC S YrhC-like protein
MLOALDAC_01099 5.2e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MLOALDAC_01100 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MLOALDAC_01101 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLOALDAC_01102 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MLOALDAC_01103 4.1e-27 yrzA S Protein of unknown function (DUF2536)
MLOALDAC_01104 3.1e-69 yrrS S Protein of unknown function (DUF1510)
MLOALDAC_01105 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MLOALDAC_01106 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MLOALDAC_01107 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
MLOALDAC_01108 1.6e-246 yegQ O COG0826 Collagenase and related proteases
MLOALDAC_01109 1.7e-173 yegQ O Peptidase U32
MLOALDAC_01110 2.1e-117 yrrM 2.1.1.104 S O-methyltransferase
MLOALDAC_01111 5.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLOALDAC_01112 7.1e-46 yrzB S Belongs to the UPF0473 family
MLOALDAC_01113 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLOALDAC_01114 8.5e-41 yrzL S Belongs to the UPF0297 family
MLOALDAC_01115 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLOALDAC_01116 6.4e-164 yrrI S AI-2E family transporter
MLOALDAC_01117 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLOALDAC_01118 5.5e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
MLOALDAC_01119 1.2e-109 gluC P ABC transporter
MLOALDAC_01120 2.2e-106 glnP P ABC transporter
MLOALDAC_01121 2.1e-08 S Protein of unknown function (DUF3918)
MLOALDAC_01122 2.9e-30 yrzR
MLOALDAC_01123 1.8e-83 yrrD S protein conserved in bacteria
MLOALDAC_01124 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MLOALDAC_01125 1.7e-18 S COG0457 FOG TPR repeat
MLOALDAC_01126 7e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MLOALDAC_01127 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
MLOALDAC_01128 7.8e-64 cymR K Transcriptional regulator
MLOALDAC_01129 2.8e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MLOALDAC_01130 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MLOALDAC_01131 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MLOALDAC_01132 2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MLOALDAC_01135 2.6e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
MLOALDAC_01136 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MLOALDAC_01137 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MLOALDAC_01138 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLOALDAC_01139 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MLOALDAC_01140 1.1e-45 yrvD S Lipopolysaccharide assembly protein A domain
MLOALDAC_01141 9.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MLOALDAC_01142 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MLOALDAC_01143 1.3e-50 yrzD S Post-transcriptional regulator
MLOALDAC_01144 2.1e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLOALDAC_01145 9.5e-110 yrbG S membrane
MLOALDAC_01146 2.4e-60 yrzE S Protein of unknown function (DUF3792)
MLOALDAC_01147 5.6e-37 yajC U Preprotein translocase subunit YajC
MLOALDAC_01148 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MLOALDAC_01149 1.8e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MLOALDAC_01150 1.6e-20 yrzS S Protein of unknown function (DUF2905)
MLOALDAC_01151 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MLOALDAC_01152 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MLOALDAC_01153 1.2e-91 bofC S BofC C-terminal domain
MLOALDAC_01155 3e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLOALDAC_01156 8.8e-146 safA M spore coat assembly protein SafA
MLOALDAC_01157 2.4e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MLOALDAC_01158 2.8e-154 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MLOALDAC_01159 1.2e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MLOALDAC_01160 2.7e-224 nifS 2.8.1.7 E Cysteine desulfurase
MLOALDAC_01161 3.2e-95 niaR S small molecule binding protein (contains 3H domain)
MLOALDAC_01162 3.5e-160 pheA 4.2.1.51 E Prephenate dehydratase
MLOALDAC_01163 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MLOALDAC_01164 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLOALDAC_01165 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MLOALDAC_01166 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MLOALDAC_01167 3.2e-56 ysxB J ribosomal protein
MLOALDAC_01168 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
MLOALDAC_01169 1.2e-160 spoIVFB S Stage IV sporulation protein
MLOALDAC_01170 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MLOALDAC_01171 8e-143 minD D Belongs to the ParA family
MLOALDAC_01172 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MLOALDAC_01173 1.4e-84 mreD M shape-determining protein
MLOALDAC_01174 1.2e-157 mreC M Involved in formation and maintenance of cell shape
MLOALDAC_01175 4e-184 mreB D Rod shape-determining protein MreB
MLOALDAC_01176 1.8e-127 radC E Belongs to the UPF0758 family
MLOALDAC_01177 1.2e-100 maf D septum formation protein Maf
MLOALDAC_01178 8.7e-139 spoIIB S Sporulation related domain
MLOALDAC_01179 3.5e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MLOALDAC_01180 1.9e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MLOALDAC_01181 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MLOALDAC_01182 2.1e-25
MLOALDAC_01183 3.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLOALDAC_01184 7.9e-220 spoVID M stage VI sporulation protein D
MLOALDAC_01185 2.3e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MLOALDAC_01186 2.3e-184 hemB 4.2.1.24 H Belongs to the ALAD family
MLOALDAC_01187 8.6e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MLOALDAC_01188 2.1e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MLOALDAC_01189 3.6e-146 hemX O cytochrome C
MLOALDAC_01190 7e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MLOALDAC_01191 2.9e-87 ysxD
MLOALDAC_01192 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
MLOALDAC_01193 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MLOALDAC_01194 1.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MLOALDAC_01195 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLOALDAC_01196 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MLOALDAC_01197 7.1e-189 ysoA H Tetratricopeptide repeat
MLOALDAC_01198 5.8e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLOALDAC_01199 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLOALDAC_01200 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MLOALDAC_01201 2.1e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MLOALDAC_01202 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MLOALDAC_01203 5.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
MLOALDAC_01204 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MLOALDAC_01207 5e-27
MLOALDAC_01208 6.2e-43 pinR3 L Resolvase, N terminal domain
MLOALDAC_01209 8.4e-12 pinR3 L Resolvase, N terminal domain
MLOALDAC_01210 9.2e-83 hsdS 3.1.21.3 L COG0732 Restriction endonuclease S subunits
MLOALDAC_01211 4.4e-245 hsdM 2.1.1.72 L type I restriction-modification system
MLOALDAC_01212 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
MLOALDAC_01215 2.6e-91 ysnB S Phosphoesterase
MLOALDAC_01216 2.1e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLOALDAC_01217 1.5e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MLOALDAC_01218 2.4e-198 gerM S COG5401 Spore germination protein
MLOALDAC_01219 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MLOALDAC_01220 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MLOALDAC_01221 2e-30 gerE K Transcriptional regulator
MLOALDAC_01222 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MLOALDAC_01223 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MLOALDAC_01224 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MLOALDAC_01225 4.8e-108 sdhC C succinate dehydrogenase
MLOALDAC_01226 5.9e-79 yslB S Protein of unknown function (DUF2507)
MLOALDAC_01227 7e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MLOALDAC_01228 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MLOALDAC_01229 2.5e-52 trxA O Belongs to the thioredoxin family
MLOALDAC_01230 2e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MLOALDAC_01231 1.9e-178 etfA C Electron transfer flavoprotein
MLOALDAC_01232 3.3e-138 etfB C Electron transfer flavoprotein
MLOALDAC_01233 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MLOALDAC_01234 9.2e-104 fadR K Transcriptional regulator
MLOALDAC_01235 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MLOALDAC_01236 2.7e-123 ywbB S Protein of unknown function (DUF2711)
MLOALDAC_01237 4.7e-67 yshE S membrane
MLOALDAC_01238 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MLOALDAC_01239 0.0 polX L COG1796 DNA polymerase IV (family X)
MLOALDAC_01240 1.6e-83 cvpA S membrane protein, required for colicin V production
MLOALDAC_01241 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MLOALDAC_01242 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLOALDAC_01243 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLOALDAC_01244 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLOALDAC_01245 1.4e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLOALDAC_01246 2e-32 sspI S Belongs to the SspI family
MLOALDAC_01247 2.6e-205 ysfB KT regulator
MLOALDAC_01248 1.4e-259 glcD 1.1.3.15 C FAD binding domain
MLOALDAC_01249 3.4e-255 glcF C Glycolate oxidase
MLOALDAC_01250 0.0 cstA T Carbon starvation protein
MLOALDAC_01251 1.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MLOALDAC_01252 4.4e-144 araQ G transport system permease
MLOALDAC_01253 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
MLOALDAC_01254 1.8e-253 araN G carbohydrate transport
MLOALDAC_01255 1.9e-225 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MLOALDAC_01256 4.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MLOALDAC_01257 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MLOALDAC_01258 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MLOALDAC_01259 2.8e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MLOALDAC_01260 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MLOALDAC_01261 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
MLOALDAC_01262 9.2e-68 ysdB S Sigma-w pathway protein YsdB
MLOALDAC_01263 2e-42 ysdA S Membrane
MLOALDAC_01264 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLOALDAC_01265 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MLOALDAC_01266 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLOALDAC_01267 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MLOALDAC_01268 3.1e-40 lrgA S effector of murein hydrolase LrgA
MLOALDAC_01269 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
MLOALDAC_01270 0.0 lytS 2.7.13.3 T Histidine kinase
MLOALDAC_01271 7.1e-152 ysaA S HAD-hyrolase-like
MLOALDAC_01272 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLOALDAC_01273 2.3e-153 ytxC S YtxC-like family
MLOALDAC_01274 2.7e-109 ytxB S SNARE associated Golgi protein
MLOALDAC_01275 4.3e-172 dnaI L Primosomal protein DnaI
MLOALDAC_01276 4.5e-258 dnaB L Membrane attachment protein
MLOALDAC_01277 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLOALDAC_01278 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MLOALDAC_01279 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLOALDAC_01280 2e-67 ytcD K Transcriptional regulator
MLOALDAC_01281 2.2e-205 ytbD EGP Major facilitator Superfamily
MLOALDAC_01282 1.5e-160 ytbE S reductase
MLOALDAC_01283 4e-99 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MLOALDAC_01284 9.5e-107 ytaF P Probably functions as a manganese efflux pump
MLOALDAC_01285 1.6e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MLOALDAC_01286 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLOALDAC_01287 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MLOALDAC_01288 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_01289 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MLOALDAC_01290 3.1e-242 icd 1.1.1.42 C isocitrate
MLOALDAC_01291 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MLOALDAC_01292 5.5e-53
MLOALDAC_01293 3.2e-47 yjdF S Protein of unknown function (DUF2992)
MLOALDAC_01294 4.3e-72 yeaL S membrane
MLOALDAC_01295 1.1e-193 ytvI S sporulation integral membrane protein YtvI
MLOALDAC_01296 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MLOALDAC_01297 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MLOALDAC_01298 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MLOALDAC_01299 3.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MLOALDAC_01300 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLOALDAC_01301 1.3e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
MLOALDAC_01302 0.0 dnaE 2.7.7.7 L DNA polymerase
MLOALDAC_01303 3.2e-56 ytrH S Sporulation protein YtrH
MLOALDAC_01304 2.5e-86 ytrI
MLOALDAC_01305 4.4e-23
MLOALDAC_01306 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MLOALDAC_01307 2.4e-47 ytpI S YtpI-like protein
MLOALDAC_01308 3.7e-238 ytoI K transcriptional regulator containing CBS domains
MLOALDAC_01309 2.5e-129 ytkL S Belongs to the UPF0173 family
MLOALDAC_01310 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLOALDAC_01312 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
MLOALDAC_01313 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MLOALDAC_01314 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MLOALDAC_01315 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MLOALDAC_01316 1.4e-184 ytxK 2.1.1.72 L DNA methylase
MLOALDAC_01317 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MLOALDAC_01318 1.6e-60 ytfJ S Sporulation protein YtfJ
MLOALDAC_01319 3.8e-109 ytfI S Protein of unknown function (DUF2953)
MLOALDAC_01320 1.7e-87 yteJ S RDD family
MLOALDAC_01321 4.2e-181 sppA OU signal peptide peptidase SppA
MLOALDAC_01322 1.7e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLOALDAC_01323 0.0 ytcJ S amidohydrolase
MLOALDAC_01324 6.5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLOALDAC_01325 3.9e-31 sspB S spore protein
MLOALDAC_01326 7.3e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLOALDAC_01327 1.2e-208 iscS2 2.8.1.7 E Cysteine desulfurase
MLOALDAC_01328 4e-240 braB E Component of the transport system for branched-chain amino acids
MLOALDAC_01329 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MLOALDAC_01330 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MLOALDAC_01331 1.7e-108 yttP K Transcriptional regulator
MLOALDAC_01332 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
MLOALDAC_01333 2.7e-284 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MLOALDAC_01334 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLOALDAC_01335 4.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MLOALDAC_01336 1.5e-100 yokH G SMI1 / KNR4 family
MLOALDAC_01337 1.1e-64 D nuclear chromosome segregation
MLOALDAC_01340 6.2e-46 S HicB_like antitoxin of bacterial toxin-antitoxin system
MLOALDAC_01341 7.5e-18 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLOALDAC_01342 1.9e-40 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MLOALDAC_01344 1.7e-221 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLOALDAC_01345 7.3e-09
MLOALDAC_01346 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
MLOALDAC_01348 5.9e-140 E GDSL-like Lipase/Acylhydrolase family
MLOALDAC_01349 1.9e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLOALDAC_01350 4.4e-149 K Transcriptional regulator
MLOALDAC_01351 2.6e-124 azlC E AzlC protein
MLOALDAC_01352 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
MLOALDAC_01353 9.4e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLOALDAC_01354 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MLOALDAC_01355 8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MLOALDAC_01356 2.5e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
MLOALDAC_01357 2.1e-229 acuC BQ histone deacetylase
MLOALDAC_01358 3.7e-120 motS N Flagellar motor protein
MLOALDAC_01359 5.1e-145 motA N flagellar motor
MLOALDAC_01360 2.9e-182 ccpA K catabolite control protein A
MLOALDAC_01361 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MLOALDAC_01362 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
MLOALDAC_01363 1.7e-16 ytxH S COG4980 Gas vesicle protein
MLOALDAC_01364 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLOALDAC_01365 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MLOALDAC_01366 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MLOALDAC_01367 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MLOALDAC_01368 3.7e-148 ytpQ S Belongs to the UPF0354 family
MLOALDAC_01369 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MLOALDAC_01370 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MLOALDAC_01371 2.2e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MLOALDAC_01372 1.7e-51 ytzB S small secreted protein
MLOALDAC_01373 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MLOALDAC_01374 1.6e-165 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MLOALDAC_01375 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MLOALDAC_01376 3.5e-45 ytzH S YtzH-like protein
MLOALDAC_01377 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
MLOALDAC_01378 1.2e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MLOALDAC_01379 5.8e-169 ytlQ
MLOALDAC_01380 6.1e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MLOALDAC_01381 3.9e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MLOALDAC_01382 1e-270 pepV 3.5.1.18 E Dipeptidase
MLOALDAC_01383 3.4e-228 pbuO S permease
MLOALDAC_01384 6.4e-218 ythQ U Bacterial ABC transporter protein EcsB
MLOALDAC_01385 1.7e-128 ythP V ABC transporter
MLOALDAC_01386 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MLOALDAC_01387 8.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLOALDAC_01388 7.7e-294 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLOALDAC_01389 1.3e-235 ytfP S HI0933-like protein
MLOALDAC_01390 5.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MLOALDAC_01391 9e-26 yteV S Sporulation protein Cse60
MLOALDAC_01392 4.4e-186 msmR K Transcriptional regulator
MLOALDAC_01393 9.4e-247 msmE G Bacterial extracellular solute-binding protein
MLOALDAC_01394 4.8e-168 amyD G Binding-protein-dependent transport system inner membrane component
MLOALDAC_01395 6.9e-142 amyC P ABC transporter (permease)
MLOALDAC_01396 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MLOALDAC_01397 4.6e-85 M Acetyltransferase (GNAT) domain
MLOALDAC_01398 5.6e-52 ytwF P Sulfurtransferase
MLOALDAC_01399 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MLOALDAC_01400 1.2e-52 ytvB S Protein of unknown function (DUF4257)
MLOALDAC_01401 6.9e-139 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MLOALDAC_01402 2e-206 yttB EGP Major facilitator Superfamily
MLOALDAC_01403 5.9e-129 ywaF S Integral membrane protein
MLOALDAC_01404 0.0 bceB V ABC transporter (permease)
MLOALDAC_01405 5.8e-135 bceA V ABC transporter, ATP-binding protein
MLOALDAC_01406 7e-170 T PhoQ Sensor
MLOALDAC_01407 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_01408 3.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MLOALDAC_01409 1.3e-125 ytrE V ABC transporter, ATP-binding protein
MLOALDAC_01410 1e-160
MLOALDAC_01411 2.7e-172 P ABC-2 family transporter protein
MLOALDAC_01412 3.2e-162 S ABC-2 family transporter protein
MLOALDAC_01413 3.8e-162 ytrB P abc transporter atp-binding protein
MLOALDAC_01414 3.9e-66 ytrA K GntR family transcriptional regulator
MLOALDAC_01416 1.3e-39 ytzC S Protein of unknown function (DUF2524)
MLOALDAC_01417 2.1e-190 yhcC S Fe-S oxidoreductase
MLOALDAC_01418 8.7e-107 ytqB J Putative rRNA methylase
MLOALDAC_01420 2.1e-143 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
MLOALDAC_01421 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MLOALDAC_01422 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
MLOALDAC_01423 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MLOALDAC_01424 1.9e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MLOALDAC_01425 0.0 asnB 6.3.5.4 E Asparagine synthase
MLOALDAC_01426 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLOALDAC_01427 1.7e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MLOALDAC_01428 1.6e-38 ytmB S Protein of unknown function (DUF2584)
MLOALDAC_01429 1.8e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MLOALDAC_01430 3.6e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MLOALDAC_01431 3.2e-144 ytlC P ABC transporter
MLOALDAC_01432 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MLOALDAC_01433 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MLOALDAC_01434 1.7e-61 ytkC S Bacteriophage holin family
MLOALDAC_01435 1.6e-76 dps P Belongs to the Dps family
MLOALDAC_01437 2.7e-76 ytkA S YtkA-like
MLOALDAC_01438 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MLOALDAC_01439 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MLOALDAC_01440 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MLOALDAC_01441 1.6e-41 rpmE2 J Ribosomal protein L31
MLOALDAC_01442 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
MLOALDAC_01443 2.6e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MLOALDAC_01444 2.3e-24 S Domain of Unknown Function (DUF1540)
MLOALDAC_01445 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MLOALDAC_01446 1.7e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MLOALDAC_01447 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MLOALDAC_01448 6.5e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MLOALDAC_01449 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MLOALDAC_01450 6.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
MLOALDAC_01451 2e-132 dksA T COG1734 DnaK suppressor protein
MLOALDAC_01452 9e-78 tspO T membrane
MLOALDAC_01461 7.8e-08
MLOALDAC_01462 1.3e-09
MLOALDAC_01469 1.6e-08
MLOALDAC_01474 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLOALDAC_01475 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLOALDAC_01476 8.1e-38 yaaB S Domain of unknown function (DUF370)
MLOALDAC_01477 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLOALDAC_01478 6.9e-33 yaaA S S4 domain
MLOALDAC_01479 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MLOALDAC_01480 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLOALDAC_01481 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MLOALDAC_01482 9.5e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MLOALDAC_01483 1.4e-110 jag S single-stranded nucleic acid binding R3H
MLOALDAC_01484 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLOALDAC_01485 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MLOALDAC_01486 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MLOALDAC_01487 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MLOALDAC_01488 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
MLOALDAC_01489 7.9e-149 spo0J K Belongs to the ParB family
MLOALDAC_01490 1.5e-109 yyaC S Sporulation protein YyaC
MLOALDAC_01491 1.1e-30 4.2.1.103 K FR47-like protein
MLOALDAC_01492 3.1e-176 yyaD S Membrane
MLOALDAC_01493 2.3e-33 yyzM S protein conserved in bacteria
MLOALDAC_01494 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLOALDAC_01495 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MLOALDAC_01496 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MLOALDAC_01497 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MLOALDAC_01498 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLOALDAC_01499 3.9e-107 adaA 3.2.2.21 K Transcriptional regulator
MLOALDAC_01500 1.8e-101 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLOALDAC_01501 3.1e-144 xth 3.1.11.2 L exodeoxyribonuclease III
MLOALDAC_01502 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MLOALDAC_01503 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLOALDAC_01504 6.2e-249 ydjK G Sugar (and other) transporter
MLOALDAC_01505 4.1e-164 yyaK S CAAX protease self-immunity
MLOALDAC_01506 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MLOALDAC_01507 3e-130 ydfC EG EamA-like transporter family
MLOALDAC_01508 3.9e-249 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLOALDAC_01509 5.4e-41 qacC U Small Multidrug Resistance protein
MLOALDAC_01510 1.7e-96
MLOALDAC_01511 5.8e-141 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MLOALDAC_01512 1.7e-165 K Transcriptional regulator
MLOALDAC_01513 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
MLOALDAC_01514 6.8e-164 eaeH M Domain of Unknown Function (DUF1259)
MLOALDAC_01515 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
MLOALDAC_01516 2.5e-77 yybA 2.3.1.57 K transcriptional
MLOALDAC_01517 3.8e-154 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MLOALDAC_01518 3.5e-68 ydgJ K Winged helix DNA-binding domain
MLOALDAC_01519 5.6e-115 drgA C nitroreductase
MLOALDAC_01520 1.3e-55 ypaA S Protein of unknown function (DUF1304)
MLOALDAC_01521 1.8e-164 gltC K Transcriptional regulator
MLOALDAC_01522 2.8e-216 ynfM EGP Major facilitator Superfamily
MLOALDAC_01523 1.1e-100 E LysE type translocator
MLOALDAC_01524 9.9e-163 yfiE K LysR substrate binding domain
MLOALDAC_01525 3.7e-77 H porphobilinogen synthase activity
MLOALDAC_01526 1.1e-77 eamA1 EG spore germination
MLOALDAC_01527 1.3e-243 trpE 2.6.1.85, 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLOALDAC_01528 1.9e-14 comA K response regulator
MLOALDAC_01529 2e-161 G Major Facilitator Superfamily
MLOALDAC_01530 5.4e-76 dinB S PFAM DinB family protein
MLOALDAC_01531 1.8e-116 K FCD domain
MLOALDAC_01532 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
MLOALDAC_01533 2.2e-273 sacB 2.4.1.10 GH68 M levansucrase activity
MLOALDAC_01534 2.8e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLOALDAC_01535 5e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MLOALDAC_01536 2.8e-66 ydeP3 K Transcriptional regulator
MLOALDAC_01537 6.5e-85 cotF M Spore coat protein
MLOALDAC_01539 1.6e-158 yybS S membrane
MLOALDAC_01540 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MLOALDAC_01541 4.9e-73 rplI J binds to the 23S rRNA
MLOALDAC_01542 7.2e-90 KLT COG0515 Serine threonine protein kinase
MLOALDAC_01543 2.7e-120 S GlcNAc-PI de-N-acetylase
MLOALDAC_01544 1.3e-235 M Glycosyltransferase Family 4
MLOALDAC_01545 9.1e-236 S Carbamoyl-phosphate synthase L chain, ATP binding domain
MLOALDAC_01546 1.9e-205 S Ecdysteroid kinase
MLOALDAC_01547 2.7e-241 M Glycosyltransferase Family 4
MLOALDAC_01548 3.5e-17 yycC K YycC-like protein
MLOALDAC_01550 8e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MLOALDAC_01551 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MLOALDAC_01552 9.1e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLOALDAC_01553 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLOALDAC_01558 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_01559 0.0 vicK 2.7.13.3 T Histidine kinase
MLOALDAC_01560 1.2e-260 yycH S protein conserved in bacteria
MLOALDAC_01561 1.3e-151 yycI S protein conserved in bacteria
MLOALDAC_01562 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MLOALDAC_01563 1.2e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLOALDAC_01564 1.6e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_01565 1.7e-252 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
MLOALDAC_01566 7.6e-191 2.7.7.73, 2.7.7.80 H ThiF family
MLOALDAC_01567 1.4e-261
MLOALDAC_01568 3.4e-198 S Major Facilitator Superfamily
MLOALDAC_01569 8.8e-306 S ABC transporter
MLOALDAC_01570 3.4e-145 1.14.11.27 P peptidyl-arginine hydroxylation
MLOALDAC_01571 2.2e-260 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MLOALDAC_01572 2.2e-42 sdpR K transcriptional
MLOALDAC_01573 8.8e-60 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MLOALDAC_01574 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MLOALDAC_01575 4.5e-258 rocE E amino acid
MLOALDAC_01576 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MLOALDAC_01577 8.9e-201 S Histidine kinase
MLOALDAC_01579 9.7e-88 yycN 2.3.1.128 K Acetyltransferase
MLOALDAC_01580 5.1e-184 C oxidoreductases (related to aryl-alcohol dehydrogenases)
MLOALDAC_01581 1.8e-133 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MLOALDAC_01582 1.7e-218 yycP
MLOALDAC_01584 7.9e-08 S YyzF-like protein
MLOALDAC_01585 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLOALDAC_01587 5.4e-08
MLOALDAC_01589 9.8e-93 S Uncharacterised protein conserved in bacteria (DUF2326)
MLOALDAC_01590 1e-179 S Fusaric acid resistance protein-like
MLOALDAC_01591 2.3e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MLOALDAC_01592 5.5e-91 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MLOALDAC_01593 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MLOALDAC_01594 3.9e-156 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MLOALDAC_01595 1.5e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MLOALDAC_01596 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MLOALDAC_01597 4.2e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
MLOALDAC_01598 1e-229 XK27_00240 S Fic/DOC family
MLOALDAC_01599 2.3e-287 ahpF O Alkyl hydroperoxide reductase
MLOALDAC_01600 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MLOALDAC_01601 1.3e-128 E Ring-cleavage extradiol dioxygenase
MLOALDAC_01602 2e-74 yxaI S membrane protein domain
MLOALDAC_01603 2.6e-203 EGP Major facilitator Superfamily
MLOALDAC_01604 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
MLOALDAC_01605 6e-65 S Family of unknown function (DUF5391)
MLOALDAC_01606 1.7e-139 S PQQ-like domain
MLOALDAC_01607 2.5e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MLOALDAC_01608 1.6e-216 yxbF K Bacterial regulatory proteins, tetR family
MLOALDAC_01609 9e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MLOALDAC_01610 1.7e-199 desK 2.7.13.3 T Histidine kinase
MLOALDAC_01611 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLOALDAC_01612 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
MLOALDAC_01614 0.0 htpG O Molecular chaperone. Has ATPase activity
MLOALDAC_01615 6.7e-246 csbC EGP Major facilitator Superfamily
MLOALDAC_01616 4.9e-176 iolS C Aldo keto reductase
MLOALDAC_01617 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
MLOALDAC_01618 2.1e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLOALDAC_01619 1.5e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MLOALDAC_01620 5.7e-183 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MLOALDAC_01621 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MLOALDAC_01622 3.8e-178 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MLOALDAC_01623 6e-233 iolF EGP Major facilitator Superfamily
MLOALDAC_01624 9.5e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MLOALDAC_01625 1.9e-166 iolH G Xylose isomerase-like TIM barrel
MLOALDAC_01626 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MLOALDAC_01627 1.9e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MLOALDAC_01628 4.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_01629 3.9e-176 T PhoQ Sensor
MLOALDAC_01630 3.6e-140 yxdL V ABC transporter, ATP-binding protein
MLOALDAC_01631 0.0 yxdM V ABC transporter (permease)
MLOALDAC_01632 7.6e-58 yxeA S Protein of unknown function (DUF1093)
MLOALDAC_01633 2.4e-178 fhuD P Periplasmic binding protein
MLOALDAC_01634 6e-35
MLOALDAC_01635 8.4e-23 yxeD
MLOALDAC_01636 6.4e-13 yxeE
MLOALDAC_01639 1.2e-149 yidA S hydrolases of the HAD superfamily
MLOALDAC_01640 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLOALDAC_01641 3.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLOALDAC_01642 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLOALDAC_01643 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MLOALDAC_01644 1.7e-252 lysP E amino acid
MLOALDAC_01645 3.8e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MLOALDAC_01646 5.5e-239 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MLOALDAC_01647 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MLOALDAC_01648 2.5e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
MLOALDAC_01649 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MLOALDAC_01650 1.3e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MLOALDAC_01651 1.1e-63 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MLOALDAC_01653 0.0 L HKD family nuclease
MLOALDAC_01654 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLOALDAC_01655 4.2e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLOALDAC_01656 9.8e-74 yxiE T Belongs to the universal stress protein A family
MLOALDAC_01657 1.2e-147 yxxF EG EamA-like transporter family
MLOALDAC_01658 1e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
MLOALDAC_01661 1e-64 yxxG
MLOALDAC_01662 2.6e-73 yxiG
MLOALDAC_01665 3.1e-31
MLOALDAC_01666 1e-78
MLOALDAC_01667 3.2e-110
MLOALDAC_01668 5.1e-15 S YxiJ-like protein
MLOALDAC_01669 2.3e-22
MLOALDAC_01671 1.1e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MLOALDAC_01672 6.4e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
MLOALDAC_01673 7e-150 licT K transcriptional antiterminator
MLOALDAC_01674 1.5e-143 exoK GH16 M licheninase activity
MLOALDAC_01675 6.2e-222 citH C Citrate transporter
MLOALDAC_01676 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MLOALDAC_01677 1.4e-50 yxiS
MLOALDAC_01678 3e-74 T Domain of unknown function (DUF4163)
MLOALDAC_01679 3.8e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLOALDAC_01680 7.6e-163 rlmA 2.1.1.187 Q Methyltransferase domain
MLOALDAC_01681 1.4e-217 yxjG 2.1.1.14 E Methionine synthase
MLOALDAC_01682 1.8e-86 yxjI S LURP-one-related
MLOALDAC_01685 1.9e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MLOALDAC_01686 1.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MLOALDAC_01687 3.8e-87 yxkC S Domain of unknown function (DUF4352)
MLOALDAC_01688 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLOALDAC_01689 8.8e-167 lrp QT PucR C-terminal helix-turn-helix domain
MLOALDAC_01690 1e-204 msmK P Belongs to the ABC transporter superfamily
MLOALDAC_01691 7.1e-158 yxkH G Polysaccharide deacetylase
MLOALDAC_01692 2.2e-214 cimH C COG3493 Na citrate symporter
MLOALDAC_01693 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
MLOALDAC_01694 5.5e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MLOALDAC_01695 0.0 cydD V ATP-binding
MLOALDAC_01696 4.1e-293 cydD V ATP-binding protein
MLOALDAC_01697 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLOALDAC_01698 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MLOALDAC_01699 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MLOALDAC_01700 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MLOALDAC_01701 3.8e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MLOALDAC_01702 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MLOALDAC_01703 1.3e-165 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MLOALDAC_01704 4.6e-287 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLOALDAC_01705 3.7e-230 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLOALDAC_01706 3.5e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLOALDAC_01707 2e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLOALDAC_01708 8.5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLOALDAC_01709 1.4e-59 arsR K transcriptional
MLOALDAC_01710 4e-167 cbrA3 P Periplasmic binding protein
MLOALDAC_01711 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLOALDAC_01712 1.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLOALDAC_01713 6.6e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MLOALDAC_01714 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MLOALDAC_01715 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MLOALDAC_01716 2.2e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLOALDAC_01717 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MLOALDAC_01718 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLOALDAC_01719 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MLOALDAC_01720 3.7e-229 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MLOALDAC_01721 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_01722 3.7e-229 dltB M membrane protein involved in D-alanine export
MLOALDAC_01723 4.2e-294 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_01724 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
MLOALDAC_01725 8.4e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MLOALDAC_01726 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
MLOALDAC_01727 1.9e-196 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLOALDAC_01728 1.7e-82 ywaE K Transcriptional regulator
MLOALDAC_01729 1.7e-197 aplB S Sodium:solute symporter family
MLOALDAC_01730 1.8e-111 1.1.1.1 C Iron-containing alcohol dehydrogenase
MLOALDAC_01731 1.4e-87 K Transcriptional regulator
MLOALDAC_01732 2.7e-142 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLOALDAC_01733 2.1e-237 hpaE 1.2.1.60 C Belongs to the aldehyde dehydrogenase family
MLOALDAC_01734 4.7e-242 hpaB 1.14.14.9 Q 4-hydroxyphenylacetate 3-hydroxylase C terminal
MLOALDAC_01735 1.4e-149 hpaD 1.13.11.2 E COG0346 Lactoylglutathione lyase and related lyases
MLOALDAC_01736 3.2e-174 gabD C Aldehyde dehydrogenase family
MLOALDAC_01737 7.2e-49 ribF 2.7.1.26, 2.7.7.2 H FAD synthetase
MLOALDAC_01738 1.2e-66 hpaG1 4.1.1.68 Q 4-hydroxyphenylacetate degradation bifunctional isomerase decarboxylase
MLOALDAC_01739 2.7e-111 4.1.1.68 Q 4-hydroxyphenylacetate degradation bifunctional isomerase
MLOALDAC_01740 2.5e-41 hpcD 4.1.1.68, 5.3.3.10 E 5-carboxymethyl-2-hydroxymuconate isomerase
MLOALDAC_01741 3.5e-101 drgA C nitroreductase
MLOALDAC_01742 3.3e-133 E Amino acid permease
MLOALDAC_01743 6.2e-212 2.6.1.113 H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLOALDAC_01744 1.6e-210 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MLOALDAC_01745 1.5e-130 KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MLOALDAC_01746 1.9e-111 ywaF S Integral membrane protein
MLOALDAC_01747 3.3e-163 gspA M General stress
MLOALDAC_01748 1.9e-266 epr 3.4.21.62 O Belongs to the peptidase S8 family
MLOALDAC_01749 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MLOALDAC_01750 7.6e-67 ywbC 4.4.1.5 E glyoxalase
MLOALDAC_01751 5.5e-225 ywbD 2.1.1.191 J Methyltransferase
MLOALDAC_01752 1e-170 yjfC O Predicted Zn-dependent protease (DUF2268)
MLOALDAC_01753 1.2e-140 mta K transcriptional
MLOALDAC_01754 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
MLOALDAC_01755 1.5e-110 ywbG M effector of murein hydrolase
MLOALDAC_01756 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MLOALDAC_01757 8.2e-152 ywbI K Transcriptional regulator
MLOALDAC_01758 2.1e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MLOALDAC_01759 1e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MLOALDAC_01760 4e-242 ywbN P Dyp-type peroxidase family protein
MLOALDAC_01761 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MLOALDAC_01762 1.7e-133 S Streptomycin biosynthesis protein StrF
MLOALDAC_01763 1.9e-129 H Methionine biosynthesis protein MetW
MLOALDAC_01765 4.3e-112 ywcC K Bacterial regulatory proteins, tetR family
MLOALDAC_01766 3.5e-62 gtcA S GtrA-like protein
MLOALDAC_01767 5.7e-230 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MLOALDAC_01768 9.2e-297 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MLOALDAC_01769 8.4e-27 ywzA S membrane
MLOALDAC_01770 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MLOALDAC_01771 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLOALDAC_01772 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MLOALDAC_01773 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MLOALDAC_01774 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
MLOALDAC_01775 1.4e-79 ysnE K acetyltransferase
MLOALDAC_01776 2.8e-208 rodA D Belongs to the SEDS family
MLOALDAC_01777 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MLOALDAC_01778 4.4e-183 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLOALDAC_01779 0.0 vpr O Belongs to the peptidase S8 family
MLOALDAC_01781 8.3e-151 sacT K transcriptional antiterminator
MLOALDAC_01782 1.5e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLOALDAC_01783 2.8e-287 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
MLOALDAC_01784 9.7e-20 ywdA
MLOALDAC_01785 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MLOALDAC_01786 1.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
MLOALDAC_01787 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLOALDAC_01788 2.3e-40 ywdI S Family of unknown function (DUF5327)
MLOALDAC_01789 7.5e-231 ywdJ F Xanthine uracil
MLOALDAC_01790 4.2e-46 ywdK S small membrane protein
MLOALDAC_01791 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MLOALDAC_01792 3.4e-143 spsA M Spore Coat
MLOALDAC_01793 3.4e-277 spsB M Capsule polysaccharide biosynthesis protein
MLOALDAC_01794 1.5e-222 spsC E Belongs to the DegT DnrJ EryC1 family
MLOALDAC_01795 2e-160 spsD 2.3.1.210 K Spore Coat
MLOALDAC_01796 3.4e-216 spsE 2.5.1.56 M acid synthase
MLOALDAC_01797 4.4e-135 spsF M Spore Coat
MLOALDAC_01798 3.9e-187 spsG M Spore Coat
MLOALDAC_01799 7.9e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLOALDAC_01800 6e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MLOALDAC_01801 2.8e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MLOALDAC_01802 6e-87 spsL 5.1.3.13 M Spore Coat
MLOALDAC_01803 2.1e-58
MLOALDAC_01804 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLOALDAC_01805 3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLOALDAC_01806 0.0 rocB E arginine degradation protein
MLOALDAC_01807 8.3e-260 lysP E amino acid
MLOALDAC_01808 2.4e-207 tcaB EGP Major facilitator Superfamily
MLOALDAC_01809 2.7e-222 ywfA EGP Major facilitator Superfamily
MLOALDAC_01810 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MLOALDAC_01811 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MLOALDAC_01812 4.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLOALDAC_01813 9.8e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MLOALDAC_01814 4.7e-208 bacE EGP Major facilitator Superfamily
MLOALDAC_01815 7.8e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
MLOALDAC_01816 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
MLOALDAC_01817 1.1e-146 ywfI C May function as heme-dependent peroxidase
MLOALDAC_01818 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MLOALDAC_01819 1.1e-159 MA20_14895 S Conserved hypothetical protein 698
MLOALDAC_01820 3e-162 cysL K Transcriptional regulator
MLOALDAC_01821 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MLOALDAC_01823 8.3e-187
MLOALDAC_01826 1.3e-168 yhcI S ABC transporter (permease)
MLOALDAC_01827 9.1e-167 V ABC transporter, ATP-binding protein
MLOALDAC_01828 8.1e-94 S membrane
MLOALDAC_01829 8.2e-51 padR K PadR family transcriptional regulator
MLOALDAC_01830 3e-110 rsfA_1
MLOALDAC_01831 6.9e-36 ywzC S Belongs to the UPF0741 family
MLOALDAC_01832 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
MLOALDAC_01833 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
MLOALDAC_01834 1.3e-246 yhdG_1 E C-terminus of AA_permease
MLOALDAC_01835 1.8e-69 ywhA K Transcriptional regulator
MLOALDAC_01836 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MLOALDAC_01837 1.2e-117 ywhC S Peptidase family M50
MLOALDAC_01838 1.4e-95 ywhD S YwhD family
MLOALDAC_01839 2.5e-82
MLOALDAC_01840 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLOALDAC_01841 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MLOALDAC_01842 6e-168 speB 3.5.3.11 E Belongs to the arginase family
MLOALDAC_01845 6.2e-77 CP Membrane
MLOALDAC_01847 2e-28 S Domain of unknown function (DUF4177)
MLOALDAC_01848 5e-33
MLOALDAC_01849 2.6e-29 ydcG K sequence-specific DNA binding
MLOALDAC_01851 4.1e-76 S aspartate phosphatase
MLOALDAC_01852 1.3e-214 ywhK CO amine dehydrogenase activity
MLOALDAC_01853 1.4e-227 ywhL CO amine dehydrogenase activity
MLOALDAC_01855 4.7e-73 ywiB S protein conserved in bacteria
MLOALDAC_01856 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MLOALDAC_01857 8.3e-213 narK P COG2223 Nitrate nitrite transporter
MLOALDAC_01858 5.9e-129 fnr K helix_turn_helix, cAMP Regulatory protein
MLOALDAC_01859 2.2e-139 ywiC S YwiC-like protein
MLOALDAC_01860 4.5e-85 arfM T cyclic nucleotide binding
MLOALDAC_01861 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLOALDAC_01862 2e-293 narH 1.7.5.1 C Nitrate reductase, beta
MLOALDAC_01863 2.1e-97 narJ 1.7.5.1 C nitrate reductase
MLOALDAC_01864 7.7e-123 narI 1.7.5.1 C nitrate reductase, gamma
MLOALDAC_01865 1.5e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MLOALDAC_01866 3.7e-301 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLOALDAC_01867 0.0 ywjA V ABC transporter
MLOALDAC_01868 4.2e-43 ywjC
MLOALDAC_01869 1.5e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MLOALDAC_01870 9.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MLOALDAC_01871 0.0 fadF C COG0247 Fe-S oxidoreductase
MLOALDAC_01872 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MLOALDAC_01873 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MLOALDAC_01874 1.7e-93 ywjG S Domain of unknown function (DUF2529)
MLOALDAC_01875 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
MLOALDAC_01876 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MLOALDAC_01877 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MLOALDAC_01878 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLOALDAC_01879 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MLOALDAC_01880 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MLOALDAC_01881 1.1e-32 rpmE J Binds the 23S rRNA
MLOALDAC_01882 4.1e-104 tdk 2.7.1.21 F thymidine kinase
MLOALDAC_01883 0.0 sfcA 1.1.1.38 C malic enzyme
MLOALDAC_01884 3.6e-158 ywkB S Membrane transport protein
MLOALDAC_01885 1.5e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MLOALDAC_01886 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLOALDAC_01887 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLOALDAC_01888 5.2e-156 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MLOALDAC_01890 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
MLOALDAC_01891 2e-118 spoIIR S stage II sporulation protein R
MLOALDAC_01892 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MLOALDAC_01893 1e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MLOALDAC_01894 5.8e-92 mntP P Probably functions as a manganese efflux pump
MLOALDAC_01895 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLOALDAC_01896 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MLOALDAC_01897 5.9e-97 ywlG S Belongs to the UPF0340 family
MLOALDAC_01898 3.5e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLOALDAC_01899 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLOALDAC_01900 2.1e-61 atpI S ATP synthase
MLOALDAC_01901 9.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
MLOALDAC_01902 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLOALDAC_01903 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLOALDAC_01904 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLOALDAC_01905 1.8e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLOALDAC_01906 5e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLOALDAC_01907 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLOALDAC_01908 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MLOALDAC_01909 1.2e-90 ywmA
MLOALDAC_01910 1.3e-32 ywzB S membrane
MLOALDAC_01911 1.3e-134 ywmB S TATA-box binding
MLOALDAC_01912 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLOALDAC_01913 8e-188 spoIID D Stage II sporulation protein D
MLOALDAC_01914 2.1e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MLOALDAC_01915 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MLOALDAC_01917 3.2e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MLOALDAC_01918 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MLOALDAC_01919 2.8e-93 S response regulator aspartate phosphatase
MLOALDAC_01920 8e-82 ywmF S Peptidase M50
MLOALDAC_01921 1.4e-10 csbD K CsbD-like
MLOALDAC_01922 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MLOALDAC_01923 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MLOALDAC_01924 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MLOALDAC_01925 6.1e-67 ywnA K Transcriptional regulator
MLOALDAC_01926 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MLOALDAC_01927 1.1e-52 ywnC S Family of unknown function (DUF5362)
MLOALDAC_01928 7.1e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLOALDAC_01929 9.3e-69 ywnF S Family of unknown function (DUF5392)
MLOALDAC_01930 1.5e-10 ywnC S Family of unknown function (DUF5362)
MLOALDAC_01931 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MLOALDAC_01932 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MLOALDAC_01933 1.1e-71 ywnJ S VanZ like family
MLOALDAC_01934 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MLOALDAC_01935 2.4e-209 ftsW D Belongs to the SEDS family
MLOALDAC_01936 2e-58 nrgB K Belongs to the P(II) protein family
MLOALDAC_01937 1.2e-227 amt P Ammonium transporter
MLOALDAC_01938 5.7e-103 phzA Q Isochorismatase family
MLOALDAC_01939 2e-242 ywoD EGP Major facilitator superfamily
MLOALDAC_01940 3.9e-273 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MLOALDAC_01941 3.8e-213 ywoG EGP Major facilitator Superfamily
MLOALDAC_01942 8.5e-72 ywoH K transcriptional
MLOALDAC_01943 1.8e-44 spoIIID K Stage III sporulation protein D
MLOALDAC_01944 2.7e-180 mbl D Rod shape-determining protein
MLOALDAC_01945 3.2e-128 flhO N flagellar basal body
MLOALDAC_01946 1.4e-145 flhP N flagellar basal body
MLOALDAC_01947 2.9e-201 S aspartate phosphatase
MLOALDAC_01948 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MLOALDAC_01949 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MLOALDAC_01950 1.1e-68 ywpF S YwpF-like protein
MLOALDAC_01951 4e-62 ywpG
MLOALDAC_01952 3.7e-57 ssbB L Single-stranded DNA-binding protein
MLOALDAC_01953 1.3e-137 glcR K DeoR C terminal sensor domain
MLOALDAC_01954 3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MLOALDAC_01955 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MLOALDAC_01956 2.4e-308 ywqB S SWIM zinc finger
MLOALDAC_01957 1.3e-14
MLOALDAC_01958 5.2e-112 ywqC M biosynthesis protein
MLOALDAC_01959 4.3e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MLOALDAC_01960 1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MLOALDAC_01961 9.5e-250 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLOALDAC_01962 1.1e-149 ywqG S Domain of unknown function (DUF1963)
MLOALDAC_01964 8.5e-22 S Domain of unknown function (DUF5082)
MLOALDAC_01965 9.5e-37 ywqI S Family of unknown function (DUF5344)
MLOALDAC_01966 0.0 ywqJ S Pre-toxin TG
MLOALDAC_01967 2e-49
MLOALDAC_01968 5e-64 T DNase/tRNase domain of colicin-like bacteriocin
MLOALDAC_01969 3.9e-81 S Protein of unknown function (DUF2004)
MLOALDAC_01970 3.7e-52 S protein secretion by the type VII secretion system
MLOALDAC_01971 8.7e-25
MLOALDAC_01972 4.7e-123 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MLOALDAC_01973 3.1e-156 K Transcriptional regulator
MLOALDAC_01974 6.7e-93 ywqN S NAD(P)H-dependent
MLOALDAC_01976 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
MLOALDAC_01977 1.2e-103 ywrB P Chromate transporter
MLOALDAC_01978 1.9e-83 ywrC K Transcriptional regulator
MLOALDAC_01979 6.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MLOALDAC_01980 2.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLOALDAC_01981 2.3e-09
MLOALDAC_01982 5e-212 cotH M Spore Coat
MLOALDAC_01983 7.3e-129 cotB
MLOALDAC_01984 4.4e-126 ywrJ
MLOALDAC_01985 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MLOALDAC_01987 2e-166 alsR K LysR substrate binding domain
MLOALDAC_01988 4e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MLOALDAC_01989 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MLOALDAC_01990 1.1e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
MLOALDAC_01991 2.2e-88 batE T Sh3 type 3 domain protein
MLOALDAC_01992 5.7e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MLOALDAC_01993 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
MLOALDAC_01994 3.4e-280 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MLOALDAC_01995 8.1e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MLOALDAC_01996 3.3e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLOALDAC_01997 4.7e-177 rbsR K transcriptional
MLOALDAC_01998 1.1e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
MLOALDAC_01999 1.4e-190 gerKB E Spore germination protein
MLOALDAC_02000 1e-183 gerKA EG Spore germination protein
MLOALDAC_02001 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MLOALDAC_02002 2.3e-70 pgsC S biosynthesis protein
MLOALDAC_02003 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MLOALDAC_02004 1.1e-19 ywtC
MLOALDAC_02005 5.7e-241 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MLOALDAC_02006 3.2e-34 yttA 2.7.13.3 S Pfam Transposase IS66
MLOALDAC_02007 5.5e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MLOALDAC_02008 1.9e-178 ywtF K Transcriptional regulator
MLOALDAC_02009 1.9e-248 ywtG EGP Major facilitator Superfamily
MLOALDAC_02010 7.3e-269 GT2,GT4 J Glycosyl transferase family 2
MLOALDAC_02011 1.4e-214 gerAC S Spore germination protein
MLOALDAC_02012 6.6e-196 gerBB E Spore germination protein
MLOALDAC_02013 2.8e-263 gerBA EG Spore germination protein
MLOALDAC_02014 3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MLOALDAC_02015 2.6e-243 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLOALDAC_02016 5.8e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLOALDAC_02017 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MLOALDAC_02018 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MLOALDAC_02019 8.6e-295 M Glycosyltransferase like family 2
MLOALDAC_02020 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MLOALDAC_02021 1.7e-151 tagG GM Transport permease protein
MLOALDAC_02022 2.6e-283 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MLOALDAC_02023 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MLOALDAC_02024 9.7e-211 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MLOALDAC_02025 4.3e-76 yvbF K Belongs to the GbsR family
MLOALDAC_02026 1.2e-208 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLOALDAC_02027 5.4e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLOALDAC_02028 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLOALDAC_02029 8e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLOALDAC_02030 2.3e-125 mutF V ABC transporter, ATP-binding protein
MLOALDAC_02031 1.9e-122 spaE S ABC-2 family transporter protein
MLOALDAC_02032 6.3e-137 mutG S ABC-2 family transporter protein
MLOALDAC_02033 2e-123 K Transcriptional regulatory protein, C terminal
MLOALDAC_02034 4.1e-259 T His Kinase A (phosphoacceptor) domain
MLOALDAC_02035 8.8e-53 yodB K transcriptional
MLOALDAC_02036 4e-72 yvaO K Cro/C1-type HTH DNA-binding domain
MLOALDAC_02037 7.4e-68 K transcriptional
MLOALDAC_02038 6e-35 yvzC K Transcriptional
MLOALDAC_02039 4.8e-24 secG U Preprotein translocase subunit SecG
MLOALDAC_02040 3.7e-142 est 3.1.1.1 S Carboxylesterase
MLOALDAC_02041 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MLOALDAC_02042 1.3e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MLOALDAC_02044 6.3e-48 yrdF K ribonuclease inhibitor
MLOALDAC_02045 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLOALDAC_02046 1.4e-164 ytlI K LysR substrate binding domain
MLOALDAC_02047 3e-101 ytmI K Acetyltransferase (GNAT) domain
MLOALDAC_02048 4.6e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
MLOALDAC_02049 9.9e-149 tcyK M Bacterial periplasmic substrate-binding proteins
MLOALDAC_02050 2.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
MLOALDAC_02051 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
MLOALDAC_02052 3.6e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLOALDAC_02053 2.4e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLOALDAC_02054 1.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
MLOALDAC_02055 1.7e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLOALDAC_02056 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLOALDAC_02057 4e-195 yvaA 1.1.1.371 S Oxidoreductase
MLOALDAC_02058 3.7e-48 csoR S transcriptional
MLOALDAC_02059 2.6e-29 copZ P Heavy-metal-associated domain
MLOALDAC_02060 0.0 copA 3.6.3.54 P P-type ATPase
MLOALDAC_02061 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MLOALDAC_02062 8.3e-101 bdbD O Thioredoxin
MLOALDAC_02063 6e-73 bdbC O Required for disulfide bond formation in some proteins
MLOALDAC_02064 2.6e-141 S Metallo-peptidase family M12
MLOALDAC_02065 3.1e-99 yvgT S membrane
MLOALDAC_02066 0.0 helD 3.6.4.12 L DNA helicase
MLOALDAC_02067 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MLOALDAC_02068 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MLOALDAC_02069 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MLOALDAC_02070 1.1e-86 yvgO
MLOALDAC_02071 5e-156 yvgN S reductase
MLOALDAC_02072 1.4e-201 yfiN V COG0842 ABC-type multidrug transport system, permease component
MLOALDAC_02073 1.4e-193 yfiM V ABC-2 type transporter
MLOALDAC_02074 5.6e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
MLOALDAC_02075 1.3e-180 T Histidine kinase
MLOALDAC_02076 1.1e-113 yfiK K Regulator
MLOALDAC_02077 2.3e-94 modB P COG4149 ABC-type molybdate transport system, permease component
MLOALDAC_02078 1.4e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MLOALDAC_02079 2.7e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MLOALDAC_02080 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLOALDAC_02081 3.9e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MLOALDAC_02082 3.6e-14 S Small spore protein J (Spore_SspJ)
MLOALDAC_02083 2.9e-236 yvsH E Arginine ornithine antiporter
MLOALDAC_02084 2e-126 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MLOALDAC_02085 4e-178 fhuD P ABC transporter
MLOALDAC_02086 5.6e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLOALDAC_02087 4e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLOALDAC_02088 5.4e-147 fhuC 3.6.3.34 HP ABC transporter
MLOALDAC_02089 8.4e-67 yvrL S Regulatory protein YrvL
MLOALDAC_02090 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
MLOALDAC_02091 1.6e-15 S YvrJ protein family
MLOALDAC_02092 9.9e-103 yvrI K RNA polymerase
MLOALDAC_02093 1.1e-36
MLOALDAC_02094 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_02095 0.0 T PhoQ Sensor
MLOALDAC_02096 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
MLOALDAC_02097 9e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLOALDAC_02098 1.1e-167 yvrC P ABC transporter substrate-binding protein
MLOALDAC_02099 3.3e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLOALDAC_02100 6.3e-224 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MLOALDAC_02101 2.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
MLOALDAC_02102 6.1e-230 yvqJ EGP Major facilitator Superfamily
MLOALDAC_02103 8.1e-45 liaI S membrane
MLOALDAC_02104 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MLOALDAC_02105 1.6e-128 liaG S Putative adhesin
MLOALDAC_02106 2.4e-125 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MLOALDAC_02107 5.1e-193 vraS 2.7.13.3 T Histidine kinase
MLOALDAC_02108 1.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLOALDAC_02109 6.2e-210 gerAC S Spore germination B3/ GerAC like, C-terminal
MLOALDAC_02110 5e-188 gerAB E Spore germination protein
MLOALDAC_02111 3.8e-260 gerAA EG Spore germination protein
MLOALDAC_02112 6.6e-24 S Protein of unknown function (DUF3970)
MLOALDAC_02113 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLOALDAC_02114 5e-157 yuxN K Transcriptional regulator
MLOALDAC_02115 3.4e-24
MLOALDAC_02116 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
MLOALDAC_02117 7.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_02118 5.4e-240 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLOALDAC_02119 3.6e-79 dps P Belongs to the Dps family
MLOALDAC_02120 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLOALDAC_02121 0.0 pepF2 E COG1164 Oligoendopeptidase F
MLOALDAC_02122 7.2e-45 S YusW-like protein
MLOALDAC_02123 1.4e-150 yusV 3.6.3.34 HP ABC transporter
MLOALDAC_02124 3.3e-39 yusU S Protein of unknown function (DUF2573)
MLOALDAC_02125 3.9e-190 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MLOALDAC_02126 4.1e-141 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
MLOALDAC_02127 3.9e-159 ywbI2 K Transcriptional regulator
MLOALDAC_02128 8.1e-288 yusP P Major facilitator superfamily
MLOALDAC_02129 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
MLOALDAC_02130 1.1e-53 yusN M Coat F domain
MLOALDAC_02131 3.9e-43
MLOALDAC_02132 4e-167 fadM E Proline dehydrogenase
MLOALDAC_02133 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MLOALDAC_02134 1.6e-216 fadA 2.3.1.16 I Belongs to the thiolase family
MLOALDAC_02135 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MLOALDAC_02136 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MLOALDAC_02137 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MLOALDAC_02138 3.7e-40 yusG S Protein of unknown function (DUF2553)
MLOALDAC_02139 6.4e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MLOALDAC_02140 1.6e-54 yusE CO Thioredoxin
MLOALDAC_02141 5e-57 yusD S SCP-2 sterol transfer family
MLOALDAC_02142 1.8e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLOALDAC_02143 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MLOALDAC_02144 8.7e-145 metQ P Belongs to the NlpA lipoprotein family
MLOALDAC_02145 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLOALDAC_02146 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MLOALDAC_02147 1.6e-244 sufD O assembly protein SufD
MLOALDAC_02148 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLOALDAC_02149 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MLOALDAC_02150 3e-270 sufB O FeS cluster assembly
MLOALDAC_02151 1.2e-149 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MLOALDAC_02152 1.4e-78 yncE S Protein of unknown function (DUF2691)
MLOALDAC_02153 2.1e-24
MLOALDAC_02154 9.5e-34
MLOALDAC_02155 1.9e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MLOALDAC_02156 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MLOALDAC_02158 2.7e-22 S Sporulation delaying protein SdpA
MLOALDAC_02159 3.4e-76
MLOALDAC_02160 4e-14
MLOALDAC_02161 1.3e-165 K helix_turn_helix, mercury resistance
MLOALDAC_02162 5.1e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MLOALDAC_02163 8.9e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MLOALDAC_02164 2.2e-157 yurN G Binding-protein-dependent transport system inner membrane component
MLOALDAC_02165 6.9e-164 yurM P COG0395 ABC-type sugar transport system, permease component
MLOALDAC_02166 2e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MLOALDAC_02167 1e-133 yurK K UTRA
MLOALDAC_02168 1.4e-206 msmX P Belongs to the ABC transporter superfamily
MLOALDAC_02169 4.1e-169 bsn L Ribonuclease
MLOALDAC_02170 3e-237 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MLOALDAC_02171 7.9e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MLOALDAC_02172 3.8e-213 blt EGP Major facilitator Superfamily
MLOALDAC_02174 4.7e-304 pucR QT COG2508 Regulator of polyketide synthase expression
MLOALDAC_02175 2.6e-263 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MLOALDAC_02176 5.2e-62 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
MLOALDAC_02177 2.6e-168 yunF S Protein of unknown function DUF72
MLOALDAC_02178 1.8e-145 yunE S membrane transporter protein
MLOALDAC_02179 1.8e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MLOALDAC_02180 9.6e-130 yunB S Sporulation protein YunB (Spo_YunB)
MLOALDAC_02181 5.4e-194 lytH M Peptidase, M23
MLOALDAC_02182 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MLOALDAC_02183 1.7e-47 yutD S protein conserved in bacteria
MLOALDAC_02184 1.9e-74 yutE S Protein of unknown function DUF86
MLOALDAC_02185 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MLOALDAC_02186 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MLOALDAC_02187 4.2e-197 yutH S Spore coat protein
MLOALDAC_02188 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
MLOALDAC_02189 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MLOALDAC_02190 8.9e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MLOALDAC_02191 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MLOALDAC_02192 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MLOALDAC_02193 6.7e-56 yuzD S protein conserved in bacteria
MLOALDAC_02194 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
MLOALDAC_02195 2.4e-39 yuzB S Belongs to the UPF0349 family
MLOALDAC_02196 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MLOALDAC_02197 1.6e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLOALDAC_02198 1.1e-62 erpA S Belongs to the HesB IscA family
MLOALDAC_02199 9.6e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MLOALDAC_02200 3.3e-92 rimJ 2.3.1.128 J Alanine acetyltransferase
MLOALDAC_02202 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
MLOALDAC_02204 6.2e-123 V ABC transporter
MLOALDAC_02205 3.1e-71 CP Membrane
MLOALDAC_02206 4.8e-29
MLOALDAC_02207 1.2e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MLOALDAC_02209 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
MLOALDAC_02210 4.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
MLOALDAC_02211 9.9e-28 yuiB S Putative membrane protein
MLOALDAC_02212 1.2e-117 yuiC S protein conserved in bacteria
MLOALDAC_02213 5.9e-77 yuiD S protein conserved in bacteria
MLOALDAC_02214 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MLOALDAC_02215 4e-208 yuiF S antiporter
MLOALDAC_02216 1.5e-101 bioY S Biotin biosynthesis protein
MLOALDAC_02217 4.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
MLOALDAC_02218 1.5e-166 besA S Putative esterase
MLOALDAC_02219 2.1e-135 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MLOALDAC_02220 5.2e-223 entC 5.4.4.2 HQ Isochorismate synthase
MLOALDAC_02221 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MLOALDAC_02222 3.3e-172 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MLOALDAC_02223 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_02224 1.3e-34 mbtH S MbtH-like protein
MLOALDAC_02225 8.3e-133 yukJ S Uncharacterized conserved protein (DUF2278)
MLOALDAC_02226 6.7e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MLOALDAC_02227 1.5e-228 yukF QT Transcriptional regulator
MLOALDAC_02228 3.3e-46 esxA S Belongs to the WXG100 family
MLOALDAC_02229 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
MLOALDAC_02230 3.7e-206 essB S WXG100 protein secretion system (Wss), protein YukC
MLOALDAC_02231 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MLOALDAC_02232 0.0 esaA S type VII secretion protein EsaA
MLOALDAC_02233 6.9e-78 yueC S Family of unknown function (DUF5383)
MLOALDAC_02234 4.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLOALDAC_02235 3.7e-96 yueE S phosphohydrolase
MLOALDAC_02236 1.6e-22 S Protein of unknown function (DUF2642)
MLOALDAC_02237 2.5e-187 yueF S transporter activity
MLOALDAC_02238 6.4e-34 yueG S Spore germination protein gerPA/gerPF
MLOALDAC_02239 8.2e-38 yueH S YueH-like protein
MLOALDAC_02240 2.7e-67 yueI S Protein of unknown function (DUF1694)
MLOALDAC_02241 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
MLOALDAC_02242 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLOALDAC_02243 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MLOALDAC_02244 2.3e-51 yuzC
MLOALDAC_02246 2e-62 comQ H Polyprenyl synthetase
MLOALDAC_02248 8.4e-254 comP 2.7.13.3 T Histidine kinase
MLOALDAC_02249 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLOALDAC_02250 3.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
MLOALDAC_02251 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MLOALDAC_02252 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLOALDAC_02253 9.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLOALDAC_02254 1.9e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLOALDAC_02255 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLOALDAC_02256 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MLOALDAC_02257 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MLOALDAC_02258 3.1e-12
MLOALDAC_02259 3.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
MLOALDAC_02260 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
MLOALDAC_02261 2.9e-287 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MLOALDAC_02262 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MLOALDAC_02263 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
MLOALDAC_02264 1.5e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLOALDAC_02265 9.3e-74 yufK S Family of unknown function (DUF5366)
MLOALDAC_02266 2.2e-72 yuxK S protein conserved in bacteria
MLOALDAC_02267 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MLOALDAC_02268 1.5e-185 yuxJ EGP Major facilitator Superfamily
MLOALDAC_02269 4.5e-118 kapD L the KinA pathway to sporulation
MLOALDAC_02270 6.9e-68 kapB G Kinase associated protein B
MLOALDAC_02271 1.2e-230 T PhoQ Sensor
MLOALDAC_02272 1.6e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MLOALDAC_02273 1.4e-40 yugE S Domain of unknown function (DUF1871)
MLOALDAC_02274 1.1e-155 yugF I Hydrolase
MLOALDAC_02275 9.9e-83 alaR K Transcriptional regulator
MLOALDAC_02276 5e-210 yugH 2.6.1.1 E Aminotransferase
MLOALDAC_02277 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MLOALDAC_02278 1.8e-34 yuzA S Domain of unknown function (DUF378)
MLOALDAC_02279 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MLOALDAC_02280 1.1e-228 yugK C Dehydrogenase
MLOALDAC_02281 2.7e-117 ycaC Q Isochorismatase family
MLOALDAC_02282 6.1e-97 S NADPH-dependent FMN reductase
MLOALDAC_02283 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
MLOALDAC_02285 1.3e-72 yugN S YugN-like family
MLOALDAC_02286 1.1e-181 yugO P COG1226 Kef-type K transport systems
MLOALDAC_02287 6.7e-27 mstX S Membrane-integrating protein Mistic
MLOALDAC_02288 4.5e-18
MLOALDAC_02289 8.3e-117 yugP S Zn-dependent protease
MLOALDAC_02290 3.9e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MLOALDAC_02291 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MLOALDAC_02292 3.1e-77 yugU S Uncharacterised protein family UPF0047
MLOALDAC_02293 3.3e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MLOALDAC_02294 4.8e-41
MLOALDAC_02295 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MLOALDAC_02296 4.5e-219 mcpA NT chemotaxis protein
MLOALDAC_02297 2.3e-239 mcpA NT chemotaxis protein
MLOALDAC_02298 3.5e-224 mcpA NT chemotaxis protein
MLOALDAC_02299 1.6e-237 mcpA NT chemotaxis protein
MLOALDAC_02300 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MLOALDAC_02301 1.4e-184 ygjR S Oxidoreductase
MLOALDAC_02302 9e-196 yubA S transporter activity
MLOALDAC_02303 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MLOALDAC_02305 2.3e-39
MLOALDAC_02306 3.6e-15
MLOALDAC_02307 2.6e-131 S Aspartate phosphatase response regulator
MLOALDAC_02310 3.1e-53 yjcN
MLOALDAC_02311 6.6e-124 G Cupin
MLOALDAC_02312 2.9e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLOALDAC_02313 2.5e-147 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MLOALDAC_02314 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
MLOALDAC_02315 2.1e-94 yuaB
MLOALDAC_02316 1e-96 yuaC K Belongs to the GbsR family
MLOALDAC_02317 1.2e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MLOALDAC_02318 1.6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
MLOALDAC_02319 2.5e-109 yuaD S MOSC domain
MLOALDAC_02320 1.9e-83 yuaE S DinB superfamily
MLOALDAC_02321 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MLOALDAC_02322 2.5e-177 yuaG 3.4.21.72 S protein conserved in bacteria
MLOALDAC_02323 1.1e-96 thiT S Thiamine transporter protein (Thia_YuaJ)
MLOALDAC_02324 1.4e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MLOALDAC_02325 2.6e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
MLOALDAC_02326 1.8e-246 yoeA V MATE efflux family protein
MLOALDAC_02327 2e-97 yoeB S IseA DL-endopeptidase inhibitor
MLOALDAC_02329 3.5e-97 L Integrase
MLOALDAC_02330 1.8e-34 yoeD G Helix-turn-helix domain
MLOALDAC_02331 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MLOALDAC_02332 3.6e-200 ybcL EGP Major facilitator Superfamily
MLOALDAC_02333 1.8e-50 ybzH K Helix-turn-helix domain
MLOALDAC_02334 2.8e-271 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLOALDAC_02335 5.2e-156 gltR1 K Transcriptional regulator
MLOALDAC_02336 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MLOALDAC_02337 2.9e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MLOALDAC_02338 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MLOALDAC_02339 3.9e-146 gltC K Transcriptional regulator
MLOALDAC_02340 1.1e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLOALDAC_02341 8.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLOALDAC_02342 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MLOALDAC_02343 8.9e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MLOALDAC_02344 2e-41 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MLOALDAC_02345 1.1e-138 yoxB
MLOALDAC_02346 3.2e-183 yoaB EGP Major facilitator Superfamily
MLOALDAC_02347 6.5e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
MLOALDAC_02348 1.9e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLOALDAC_02349 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLOALDAC_02350 1.1e-25 yoaF
MLOALDAC_02352 6.7e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
MLOALDAC_02353 2.4e-14
MLOALDAC_02354 9.7e-77 S SMI1-KNR4 cell-wall
MLOALDAC_02355 6.6e-106 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MLOALDAC_02356 4.2e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MLOALDAC_02357 6e-134 yobQ K helix_turn_helix, arabinose operon control protein
MLOALDAC_02358 7.5e-95 yobS K Transcriptional regulator
MLOALDAC_02359 5.5e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MLOALDAC_02360 4.2e-92 yobW
MLOALDAC_02361 3.4e-55 czrA K transcriptional
MLOALDAC_02362 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MLOALDAC_02363 8.1e-91 yozB S membrane
MLOALDAC_02364 4.7e-140 yocB J Protein required for attachment to host cells
MLOALDAC_02365 1.9e-94 yocC
MLOALDAC_02366 9.9e-188 yocD 3.4.17.13 V peptidase S66
MLOALDAC_02368 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
MLOALDAC_02369 0.0 recQ 3.6.4.12 L DNA helicase
MLOALDAC_02370 2.8e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLOALDAC_02372 2.5e-54 dksA T general stress protein
MLOALDAC_02373 7.8e-10 yocL
MLOALDAC_02374 1.7e-08
MLOALDAC_02375 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
MLOALDAC_02376 3.8e-44 yozN
MLOALDAC_02377 8.5e-37 yocN
MLOALDAC_02378 2.4e-56 yozO S Bacterial PH domain
MLOALDAC_02380 1.6e-31 yozC
MLOALDAC_02381 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MLOALDAC_02382 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MLOALDAC_02383 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
MLOALDAC_02384 1.9e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLOALDAC_02385 2.7e-161 yocS S -transporter
MLOALDAC_02386 2.8e-142 S Metallo-beta-lactamase superfamily
MLOALDAC_02387 2.7e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MLOALDAC_02388 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MLOALDAC_02389 0.0 yojO P Von Willebrand factor
MLOALDAC_02390 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
MLOALDAC_02391 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLOALDAC_02392 1.6e-227 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLOALDAC_02393 6.7e-226 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MLOALDAC_02394 2.2e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLOALDAC_02396 4.4e-242 norM V Multidrug efflux pump
MLOALDAC_02397 9.3e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLOALDAC_02398 2.5e-126 yojG S deacetylase
MLOALDAC_02399 9.7e-61 yojF S Protein of unknown function (DUF1806)
MLOALDAC_02400 6.4e-23
MLOALDAC_02401 7.8e-163 rarD S -transporter
MLOALDAC_02402 1.1e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
MLOALDAC_02404 1.6e-67 yodA S tautomerase
MLOALDAC_02405 5.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
MLOALDAC_02406 1.4e-56 yodB K transcriptional
MLOALDAC_02407 4.5e-106 yodC C nitroreductase
MLOALDAC_02408 7.9e-111 mhqD S Carboxylesterase
MLOALDAC_02409 3.8e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
MLOALDAC_02410 1.4e-19 S Protein of unknown function (DUF3311)
MLOALDAC_02411 3.5e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLOALDAC_02412 9.4e-283 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
MLOALDAC_02413 7.8e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLOALDAC_02414 4.4e-132 yydK K Transcriptional regulator
MLOALDAC_02415 1.2e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MLOALDAC_02416 2.8e-128 yodH Q Methyltransferase
MLOALDAC_02417 1.2e-33 yodI
MLOALDAC_02418 5.1e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MLOALDAC_02419 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MLOALDAC_02421 8.6e-56 yodL S YodL-like
MLOALDAC_02422 8e-103 yodM 3.6.1.27 I Acid phosphatase homologues
MLOALDAC_02423 6.2e-24 yozD S YozD-like protein
MLOALDAC_02425 1.7e-125 yodN
MLOALDAC_02426 4.1e-36 yozE S Belongs to the UPF0346 family
MLOALDAC_02427 1.4e-46 yokU S YokU-like protein, putative antitoxin
MLOALDAC_02428 3.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
MLOALDAC_02429 2.8e-157 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MLOALDAC_02430 1.5e-255 yodQ 3.5.1.16 E Acetylornithine deacetylase
MLOALDAC_02431 6.1e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MLOALDAC_02432 1.1e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MLOALDAC_02433 1.4e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLOALDAC_02434 5.4e-64 yosT L Bacterial transcription activator, effector binding domain
MLOALDAC_02436 8.3e-145 yiiD K acetyltransferase
MLOALDAC_02437 1.6e-246 cgeD M maturation of the outermost layer of the spore
MLOALDAC_02438 2.5e-41 cgeC
MLOALDAC_02439 1.2e-52 cgeA
MLOALDAC_02440 2.3e-165 cgeB S Spore maturation protein
MLOALDAC_02441 1.5e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MLOALDAC_02442 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
MLOALDAC_02447 5.6e-77 yoqH M LysM domain
MLOALDAC_02448 5.3e-193 S aspartate phosphatase
MLOALDAC_02450 1.2e-26 S Acetyltransferase (GNAT) domain
MLOALDAC_02451 1.3e-84 yokK S SMI1 / KNR4 family
MLOALDAC_02452 1.4e-89 yokJ S SMI1 / KNR4 family (SUKH-1)
MLOALDAC_02453 2.9e-251 UW nuclease activity
MLOALDAC_02454 1.5e-84 G SMI1-KNR4 cell-wall
MLOALDAC_02455 1.4e-26 yokF 3.1.31.1 L RNA catabolic process
MLOALDAC_02458 9.3e-303 yokA L Recombinase
MLOALDAC_02459 2.3e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
MLOALDAC_02460 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MLOALDAC_02461 9.2e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLOALDAC_02462 1.4e-66 ypoP K transcriptional
MLOALDAC_02463 5.5e-98 ypmS S protein conserved in bacteria
MLOALDAC_02464 2e-135 ypmR E GDSL-like Lipase/Acylhydrolase
MLOALDAC_02465 2.3e-113 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MLOALDAC_02466 2.6e-39 ypmP S Protein of unknown function (DUF2535)
MLOALDAC_02467 1.4e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLOALDAC_02468 2.9e-179 pspF K Transcriptional regulator
MLOALDAC_02469 9.3e-110 hlyIII S protein, Hemolysin III
MLOALDAC_02470 1.4e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLOALDAC_02471 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MLOALDAC_02472 2.5e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLOALDAC_02473 2.7e-114 ypjP S YpjP-like protein
MLOALDAC_02474 8.2e-129 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MLOALDAC_02475 1e-75 yphP S Belongs to the UPF0403 family
MLOALDAC_02476 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MLOALDAC_02477 1.2e-157 ypgR C COG0694 Thioredoxin-like proteins and domains
MLOALDAC_02478 2.7e-98 ypgQ S phosphohydrolase
MLOALDAC_02479 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MLOALDAC_02480 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MLOALDAC_02481 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MLOALDAC_02482 1e-30 cspD K Cold-shock protein
MLOALDAC_02483 3.3e-12 degR
MLOALDAC_02484 1.2e-36 S Protein of unknown function (DUF2564)
MLOALDAC_02485 7.4e-28 ypeQ S Zinc-finger
MLOALDAC_02486 4.5e-123 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MLOALDAC_02487 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MLOALDAC_02488 3e-66 rnhA 3.1.26.4 L Ribonuclease
MLOALDAC_02490 4.1e-164 polA 2.7.7.7 L 5'3' exonuclease
MLOALDAC_02492 3.5e-39 ypbS S Protein of unknown function (DUF2533)
MLOALDAC_02493 0.0 ypbR S Dynamin family
MLOALDAC_02494 7.2e-89 ypbQ S protein conserved in bacteria
MLOALDAC_02495 6.3e-207 bcsA Q Naringenin-chalcone synthase
MLOALDAC_02496 2.4e-107 J Acetyltransferase (GNAT) domain
MLOALDAC_02497 2.6e-49 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
MLOALDAC_02499 7.7e-100 yrdC 3.5.1.19 Q Isochorismatase family
MLOALDAC_02501 1.7e-235 pbuX F xanthine
MLOALDAC_02502 2e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MLOALDAC_02503 1e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MLOALDAC_02504 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MLOALDAC_02506 6.6e-22 S YpzG-like protein
MLOALDAC_02507 3.8e-78 yqgA
MLOALDAC_02508 7.2e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MLOALDAC_02509 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MLOALDAC_02510 4.8e-99 ypsA S Belongs to the UPF0398 family
MLOALDAC_02511 2.9e-32 cotD S Inner spore coat protein D
MLOALDAC_02513 3e-237 yprB L RNase_H superfamily
MLOALDAC_02514 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MLOALDAC_02515 7.9e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MLOALDAC_02516 3.8e-72 hspX O Belongs to the small heat shock protein (HSP20) family
MLOALDAC_02517 7.4e-50 yppG S YppG-like protein
MLOALDAC_02519 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
MLOALDAC_02522 7.5e-188 yppC S Protein of unknown function (DUF2515)
MLOALDAC_02523 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MLOALDAC_02524 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MLOALDAC_02525 8.2e-90 ypoC
MLOALDAC_02526 1.1e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MLOALDAC_02527 8.8e-130 dnaD L DNA replication protein DnaD
MLOALDAC_02528 2e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MLOALDAC_02529 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MLOALDAC_02530 4e-81 ypmB S protein conserved in bacteria
MLOALDAC_02531 6.7e-23 ypmA S Protein of unknown function (DUF4264)
MLOALDAC_02532 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MLOALDAC_02533 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MLOALDAC_02534 3.2e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MLOALDAC_02535 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MLOALDAC_02536 5.3e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MLOALDAC_02537 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MLOALDAC_02538 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MLOALDAC_02539 5.6e-132 bshB1 S proteins, LmbE homologs
MLOALDAC_02540 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MLOALDAC_02541 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MLOALDAC_02542 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MLOALDAC_02543 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MLOALDAC_02544 1.5e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
MLOALDAC_02545 5.1e-142 ypjB S sporulation protein
MLOALDAC_02546 9.2e-104 ypjA S membrane
MLOALDAC_02547 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MLOALDAC_02548 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MLOALDAC_02549 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MLOALDAC_02550 1.5e-77 ypiF S Protein of unknown function (DUF2487)
MLOALDAC_02551 2.1e-99 ypiB S Belongs to the UPF0302 family
MLOALDAC_02552 2.7e-233 S COG0457 FOG TPR repeat
MLOALDAC_02553 3.1e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MLOALDAC_02554 2.7e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MLOALDAC_02555 9.3e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLOALDAC_02556 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MLOALDAC_02557 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MLOALDAC_02558 3.3e-118 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MLOALDAC_02559 2e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MLOALDAC_02560 1.2e-159 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLOALDAC_02561 3.6e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLOALDAC_02562 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MLOALDAC_02563 8.4e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MLOALDAC_02564 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MLOALDAC_02565 8.5e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MLOALDAC_02566 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MLOALDAC_02567 3.1e-195 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MLOALDAC_02568 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MLOALDAC_02569 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MLOALDAC_02570 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MLOALDAC_02571 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
MLOALDAC_02572 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MLOALDAC_02573 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MLOALDAC_02574 4.8e-134 yphF
MLOALDAC_02575 3.3e-16 yphE S Protein of unknown function (DUF2768)
MLOALDAC_02576 1.5e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MLOALDAC_02577 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MLOALDAC_02578 1.1e-104 yphA
MLOALDAC_02579 4.7e-08 S YpzI-like protein
MLOALDAC_02580 6.5e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MLOALDAC_02581 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
MLOALDAC_02582 2.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MLOALDAC_02583 1.4e-12 S Family of unknown function (DUF5359)
MLOALDAC_02584 1.6e-61 ypfA M Flagellar protein YcgR
MLOALDAC_02585 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MLOALDAC_02586 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MLOALDAC_02587 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
MLOALDAC_02588 3.4e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MLOALDAC_02589 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MLOALDAC_02590 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MLOALDAC_02591 4.8e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
MLOALDAC_02592 5.7e-85 ypbF S Protein of unknown function (DUF2663)
MLOALDAC_02593 4e-75 ypbE M Lysin motif
MLOALDAC_02594 1.3e-99 ypbD S metal-dependent membrane protease
MLOALDAC_02595 1.1e-272 recQ 3.6.4.12 L DNA helicase
MLOALDAC_02596 3.9e-198 ypbB 5.1.3.1 S protein conserved in bacteria
MLOALDAC_02597 3.6e-41 fer C Ferredoxin
MLOALDAC_02598 4.1e-270 dtpT E amino acid peptide transporter
MLOALDAC_02599 3.7e-281 yclG M Pectate lyase superfamily protein
MLOALDAC_02601 3.1e-295 gerKA EG Spore germination protein
MLOALDAC_02602 2.9e-237 gerKC S spore germination
MLOALDAC_02603 1.9e-195 gerKB F Spore germination protein
MLOALDAC_02604 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLOALDAC_02605 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLOALDAC_02606 2.7e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
MLOALDAC_02607 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
MLOALDAC_02608 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MLOALDAC_02609 9.8e-219 yxeP 3.5.1.47 E hydrolase activity
MLOALDAC_02610 2.9e-254 yxeQ S MmgE/PrpD family
MLOALDAC_02611 3.9e-122 yclH P ABC transporter
MLOALDAC_02612 4e-222 yclI V ABC transporter (permease) YclI
MLOALDAC_02613 5.2e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_02614 3.4e-261 T PhoQ Sensor
MLOALDAC_02615 4e-79 S aspartate phosphatase
MLOALDAC_02617 3.2e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
MLOALDAC_02618 3e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLOALDAC_02619 1e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLOALDAC_02620 6.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MLOALDAC_02621 3.2e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MLOALDAC_02622 1.7e-249 ycnB EGP Major facilitator Superfamily
MLOALDAC_02623 1.2e-152 ycnC K Transcriptional regulator
MLOALDAC_02624 4e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
MLOALDAC_02625 1e-44 ycnE S Monooxygenase
MLOALDAC_02626 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MLOALDAC_02627 8.5e-265 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLOALDAC_02628 1.6e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLOALDAC_02629 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLOALDAC_02630 3.6e-149 glcU U Glucose uptake
MLOALDAC_02631 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLOALDAC_02632 1.3e-97 ycnI S protein conserved in bacteria
MLOALDAC_02633 9.4e-300 ycnJ P protein, homolog of Cu resistance protein CopC
MLOALDAC_02634 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MLOALDAC_02635 1.6e-55
MLOALDAC_02636 7.9e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MLOALDAC_02637 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MLOALDAC_02638 1.4e-206 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MLOALDAC_02639 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MLOALDAC_02641 6.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MLOALDAC_02642 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
MLOALDAC_02643 7.9e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MLOALDAC_02644 4.2e-40 ycsI S Belongs to the D-glutamate cyclase family
MLOALDAC_02645 1.3e-81 ycsI S Belongs to the D-glutamate cyclase family
MLOALDAC_02646 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MLOALDAC_02647 9.3e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MLOALDAC_02648 1.2e-130 kipR K Transcriptional regulator
MLOALDAC_02649 2.7e-117 ycsK E anatomical structure formation involved in morphogenesis
MLOALDAC_02651 5.1e-56 yczJ S biosynthesis
MLOALDAC_02652 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MLOALDAC_02653 9.8e-174 ydhF S Oxidoreductase
MLOALDAC_02654 0.0 mtlR K transcriptional regulator, MtlR
MLOALDAC_02655 5.9e-288 ydaB IQ acyl-CoA ligase
MLOALDAC_02656 3.7e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLOALDAC_02657 2.3e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MLOALDAC_02658 6.7e-113 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MLOALDAC_02659 1.4e-77 ydaG 1.4.3.5 S general stress protein
MLOALDAC_02660 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MLOALDAC_02661 1.3e-47 ydzA EGP Major facilitator Superfamily
MLOALDAC_02662 1.5e-74 lrpC K Transcriptional regulator
MLOALDAC_02663 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLOALDAC_02664 4.6e-202 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MLOALDAC_02665 7.9e-149 ydaK T Diguanylate cyclase, GGDEF domain
MLOALDAC_02666 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MLOALDAC_02667 2.5e-231 ydaM M Glycosyl transferase family group 2
MLOALDAC_02668 0.0 ydaN S Bacterial cellulose synthase subunit
MLOALDAC_02669 0.0 ydaO E amino acid
MLOALDAC_02670 3.3e-65 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MLOALDAC_02671 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MLOALDAC_02672 6.4e-39 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MLOALDAC_02673 2.4e-86 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MLOALDAC_02674 1.3e-69
MLOALDAC_02675 6.5e-43 S Histidine kinase
MLOALDAC_02676 2.3e-142 S Histidine kinase
MLOALDAC_02678 4.7e-11
MLOALDAC_02680 8.2e-70
MLOALDAC_02681 3.5e-100
MLOALDAC_02682 2.1e-39
MLOALDAC_02683 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
MLOALDAC_02685 6.5e-34 ydaT
MLOALDAC_02686 3.2e-71 yvaD S Family of unknown function (DUF5360)
MLOALDAC_02687 2.1e-53 yvaE P Small Multidrug Resistance protein
MLOALDAC_02688 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MLOALDAC_02690 9.6e-64 ydbB G Cupin domain
MLOALDAC_02691 4.5e-61 ydbC S Domain of unknown function (DUF4937
MLOALDAC_02692 2.1e-154 ydbD P Catalase
MLOALDAC_02693 6.5e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MLOALDAC_02694 3.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLOALDAC_02695 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
MLOALDAC_02696 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLOALDAC_02697 3.2e-160 ydbI S AI-2E family transporter
MLOALDAC_02698 5e-173 ydbJ V ABC transporter, ATP-binding protein
MLOALDAC_02699 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLOALDAC_02700 6.1e-52 ydbL
MLOALDAC_02701 2.4e-206 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MLOALDAC_02702 1.5e-10 S Fur-regulated basic protein B
MLOALDAC_02703 5.8e-09 S Fur-regulated basic protein A
MLOALDAC_02704 2.4e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLOALDAC_02705 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MLOALDAC_02706 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MLOALDAC_02707 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MLOALDAC_02708 1.3e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MLOALDAC_02709 2.1e-82 ydbS S Bacterial PH domain
MLOALDAC_02710 8.2e-263 ydbT S Membrane
MLOALDAC_02711 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MLOALDAC_02712 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MLOALDAC_02713 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MLOALDAC_02714 1e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLOALDAC_02715 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MLOALDAC_02716 3.2e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MLOALDAC_02717 6.1e-146 rsbR T Positive regulator of sigma-B
MLOALDAC_02718 1.8e-57 rsbS T antagonist
MLOALDAC_02719 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MLOALDAC_02720 4.6e-188 rsbU 3.1.3.3 KT phosphatase
MLOALDAC_02721 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
MLOALDAC_02722 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MLOALDAC_02723 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLOALDAC_02724 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MLOALDAC_02725 0.0 yhgF K COG2183 Transcriptional accessory protein
MLOALDAC_02726 1.7e-14
MLOALDAC_02727 1.9e-58 ydcK S Belongs to the SprT family
MLOALDAC_02736 2.1e-43
MLOALDAC_02737 3.7e-19 S LXG domain of WXG superfamily
MLOALDAC_02738 2.1e-44 yobL L nucleic acid phosphodiester bond hydrolysis
MLOALDAC_02739 6.1e-31 M nucleic acid phosphodiester bond hydrolysis
MLOALDAC_02740 1.9e-113 M1-798 KP helix_turn_helix, Arsenical Resistance Operon Repressor
MLOALDAC_02741 1.3e-43 P Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MLOALDAC_02742 2.6e-204 ydeG EGP Major facilitator superfamily
MLOALDAC_02743 3.4e-24 yyaL O Highly conserved protein containing a thioredoxin domain
MLOALDAC_02744 4.8e-71 K Transcriptional regulator
MLOALDAC_02745 1.2e-64 E LysE type translocator
MLOALDAC_02746 1.6e-57 alaS2 6.1.1.7 S Threonyl and Alanyl tRNA synthetase second additional domain
MLOALDAC_02747 3.1e-95 ywrO S Flavodoxin-like fold
MLOALDAC_02748 5.5e-232 proP EGP Transporter
MLOALDAC_02749 2.9e-48 ohrR K Transcriptional regulator
MLOALDAC_02750 1.4e-47 S Domain of unknown function with cystatin-like fold (DUF4467)
MLOALDAC_02751 3e-72 maoC I N-terminal half of MaoC dehydratase
MLOALDAC_02752 3.2e-64 yyaQ S YjbR
MLOALDAC_02753 1.7e-70 ywnA K Transcriptional regulator
MLOALDAC_02754 8.4e-111 ywnB S NAD(P)H-binding
MLOALDAC_02756 5.5e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MLOALDAC_02757 1.4e-30 cspL K Cold shock
MLOALDAC_02758 1e-78 carD K Transcription factor
MLOALDAC_02759 3.9e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MLOALDAC_02760 8e-89 S Protein of unknown function (DUF2812)
MLOALDAC_02761 2.2e-51 K Transcriptional regulator PadR-like family
MLOALDAC_02762 2.7e-152 K Transcriptional regulator
MLOALDAC_02763 6e-255 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MLOALDAC_02764 1.1e-181 S Patatin-like phospholipase
MLOALDAC_02765 3.8e-84 S DinB superfamily
MLOALDAC_02766 2.2e-63 G Cupin domain
MLOALDAC_02768 6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
MLOALDAC_02769 3.4e-79 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLOALDAC_02770 1.7e-168 czcD P COG1230 Co Zn Cd efflux system component
MLOALDAC_02771 7e-200 trkA P Oxidoreductase
MLOALDAC_02773 1e-98 yrkC G Cupin domain
MLOALDAC_02774 3.5e-86 ykkA S Protein of unknown function (DUF664)
MLOALDAC_02775 3.6e-150 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
MLOALDAC_02777 2.1e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MLOALDAC_02778 7.8e-56 ydeH
MLOALDAC_02779 3.7e-84 F nucleoside 2-deoxyribosyltransferase
MLOALDAC_02780 4.8e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLOALDAC_02781 1.2e-148 Q ubiE/COQ5 methyltransferase family
MLOALDAC_02782 5.8e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MLOALDAC_02783 1.4e-234 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MLOALDAC_02784 1.1e-165 S Sodium Bile acid symporter family
MLOALDAC_02785 1.2e-202 adhA 1.1.1.1 C alcohol dehydrogenase
MLOALDAC_02786 8e-67 yraB K helix_turn_helix, mercury resistance
MLOALDAC_02787 2.1e-222 mleN_2 C antiporter
MLOALDAC_02788 9.2e-264 K helix_turn_helix gluconate operon transcriptional repressor
MLOALDAC_02789 1.9e-112 paiB K Transcriptional regulator
MLOALDAC_02791 3.7e-108 ksgA1 I Ribosomal RNA adenine dimethylase
MLOALDAC_02792 5.4e-124 T Transcriptional regulator
MLOALDAC_02793 9.9e-189 T PhoQ Sensor
MLOALDAC_02794 2e-104 S SNARE associated Golgi protein
MLOALDAC_02795 4.2e-180 ydeR EGP Major facilitator Superfamily
MLOALDAC_02796 1.3e-102 ydeS K Transcriptional regulator
MLOALDAC_02797 7.4e-158 ydeK EG -transporter
MLOALDAC_02798 3.2e-264 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLOALDAC_02799 6.2e-48 yraD M Spore coat protein
MLOALDAC_02800 4.9e-25 yraE
MLOALDAC_02801 4.2e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLOALDAC_02802 8.4e-63 yraF M Spore coat protein
MLOALDAC_02803 2.6e-36 yraG
MLOALDAC_02804 2.3e-109 ybjJ G Major Facilitator Superfamily
MLOALDAC_02805 2.9e-76 2.7.1.2 GK Transcriptional regulator
MLOALDAC_02806 2.4e-71 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MLOALDAC_02807 2.9e-219 ydfH 2.7.13.3 T Histidine kinase
MLOALDAC_02808 1.1e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLOALDAC_02809 0.0 ydfJ S drug exporters of the RND superfamily
MLOALDAC_02810 3e-133 puuD S Peptidase C26
MLOALDAC_02811 1.9e-219 mmr U Major Facilitator Superfamily
MLOALDAC_02812 1.8e-73 yffB K Transcriptional regulator
MLOALDAC_02813 1e-298 expZ S ABC transporter
MLOALDAC_02814 7.9e-99 ynaD J Acetyltransferase (GNAT) domain
MLOALDAC_02815 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
MLOALDAC_02816 3.9e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
MLOALDAC_02817 5.1e-210 tcaB EGP Major facilitator Superfamily
MLOALDAC_02818 6.8e-226 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLOALDAC_02819 1.5e-155 K Helix-turn-helix XRE-family like proteins
MLOALDAC_02820 1.3e-123 ydhB S membrane transporter protein
MLOALDAC_02821 6.5e-81 bltD 2.3.1.57 K FR47-like protein
MLOALDAC_02822 4.1e-150 bltR K helix_turn_helix, mercury resistance
MLOALDAC_02823 3.6e-149 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MLOALDAC_02824 5.1e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MLOALDAC_02825 2.2e-145 ycgJ_1 Q ubiE/COQ5 methyltransferase family
MLOALDAC_02826 2.3e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MLOALDAC_02827 6.9e-119 ydhC K FCD
MLOALDAC_02828 4.9e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MLOALDAC_02831 2e-263 pbpE V Beta-lactamase
MLOALDAC_02833 7.2e-98 ydhK M Protein of unknown function (DUF1541)
MLOALDAC_02834 1.2e-195 pbuE EGP Major facilitator Superfamily
MLOALDAC_02835 1.3e-133 ydhQ K UTRA
MLOALDAC_02836 5.3e-119 K FCD
MLOALDAC_02837 7.4e-217 yeaN P COG2807 Cyanate permease
MLOALDAC_02838 2.6e-49 sugE P Small Multidrug Resistance protein
MLOALDAC_02839 2.3e-51 ykkC P Small Multidrug Resistance protein
MLOALDAC_02840 5.3e-104 yvdT K Transcriptional regulator
MLOALDAC_02841 1.2e-296 yveA E amino acid
MLOALDAC_02842 3.2e-166 ydhU P Catalase
MLOALDAC_02843 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MLOALDAC_02844 1.4e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
MLOALDAC_02845 7e-251 iolT EGP Major facilitator Superfamily
MLOALDAC_02848 1.6e-219 glcP G Major Facilitator Superfamily
MLOALDAC_02849 1.6e-246 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLOALDAC_02850 6.7e-181 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
MLOALDAC_02851 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
MLOALDAC_02852 2.7e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MLOALDAC_02853 8.2e-174 ybaS 1.1.1.58 S Na -dependent transporter
MLOALDAC_02854 4.3e-114 ybbA S Putative esterase
MLOALDAC_02855 1e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLOALDAC_02856 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLOALDAC_02857 2e-172 feuA P Iron-uptake system-binding protein
MLOALDAC_02858 0.0 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MLOALDAC_02859 7.8e-238 ybbC 3.2.1.52 S protein conserved in bacteria
MLOALDAC_02860 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MLOALDAC_02861 3.1e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MLOALDAC_02862 1.3e-238 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLOALDAC_02863 2e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MLOALDAC_02864 1.1e-86 ybbJ J acetyltransferase
MLOALDAC_02865 3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MLOALDAC_02871 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MLOALDAC_02872 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MLOALDAC_02873 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MLOALDAC_02874 1.6e-226 ybbR S protein conserved in bacteria
MLOALDAC_02875 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLOALDAC_02876 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MLOALDAC_02877 2.6e-155 V ATPases associated with a variety of cellular activities
MLOALDAC_02878 5.4e-105 S ABC-2 family transporter protein
MLOALDAC_02880 1.5e-18 6.3.2.14 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_02881 9.9e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_02882 8e-188 T PhoQ Sensor
MLOALDAC_02883 7.4e-138 V ABC transporter, ATP-binding protein
MLOALDAC_02884 0.0 V ABC transporter (permease)
MLOALDAC_02885 8.9e-12 cusA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLOALDAC_02886 1.2e-162 dkgB S Aldo/keto reductase family
MLOALDAC_02887 1e-93 yxaC M effector of murein hydrolase
MLOALDAC_02888 6.9e-52 S LrgA family
MLOALDAC_02889 8e-73 yxaD K helix_turn_helix multiple antibiotic resistance protein
MLOALDAC_02890 8.9e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MLOALDAC_02891 2.1e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MLOALDAC_02892 1.4e-201 T COG4585 Signal transduction histidine kinase
MLOALDAC_02893 2.5e-110 KT LuxR family transcriptional regulator
MLOALDAC_02894 1.1e-167 V COG1131 ABC-type multidrug transport system, ATPase component
MLOALDAC_02895 1e-207 V COG0842 ABC-type multidrug transport system, permease component
MLOALDAC_02896 1.9e-198 V ABC-2 family transporter protein
MLOALDAC_02897 2.2e-24
MLOALDAC_02898 4.5e-77 S Domain of unknown function (DUF4879)
MLOALDAC_02899 4.9e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
MLOALDAC_02900 1e-109 yqeB
MLOALDAC_02901 4.6e-39 ybyB
MLOALDAC_02902 2.5e-292 ybeC E amino acid
MLOALDAC_02903 9e-30
MLOALDAC_02905 3.4e-15 S Protein of unknown function (DUF2651)
MLOALDAC_02906 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLOALDAC_02907 1.7e-259 glpT G -transporter
MLOALDAC_02908 1.3e-16 S Protein of unknown function (DUF2651)
MLOALDAC_02909 1.9e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MLOALDAC_02911 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
MLOALDAC_02912 3.5e-31
MLOALDAC_02913 1.2e-82 K Helix-turn-helix XRE-family like proteins
MLOALDAC_02914 4.3e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
MLOALDAC_02915 1.1e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MLOALDAC_02916 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLOALDAC_02917 1.9e-86 ybfM S SNARE associated Golgi protein
MLOALDAC_02918 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MLOALDAC_02919 1.2e-42 ybfN
MLOALDAC_02920 9.5e-191 yceA S Belongs to the UPF0176 family
MLOALDAC_02921 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLOALDAC_02922 2.1e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MLOALDAC_02923 6.1e-258 mmuP E amino acid
MLOALDAC_02924 7.1e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MLOALDAC_02925 5.4e-259 agcS E Sodium alanine symporter
MLOALDAC_02926 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
MLOALDAC_02927 1.5e-212 phoQ 2.7.13.3 T Histidine kinase
MLOALDAC_02928 5.7e-172 glnL T Regulator
MLOALDAC_02929 1.2e-29 ycbJ S Macrolide 2'-phosphotransferase
MLOALDAC_02930 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MLOALDAC_02931 3.1e-156 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLOALDAC_02932 1.5e-112 ydfN C nitroreductase
MLOALDAC_02933 7.6e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MLOALDAC_02934 1.5e-62 mhqP S DoxX
MLOALDAC_02935 2e-55 traF CO Thioredoxin
MLOALDAC_02936 5.6e-62 ycbP S Protein of unknown function (DUF2512)
MLOALDAC_02937 5.3e-77 sleB 3.5.1.28 M Cell wall
MLOALDAC_02938 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MLOALDAC_02939 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLOALDAC_02940 5.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLOALDAC_02941 2.2e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MLOALDAC_02942 6.2e-210 ycbU E Selenocysteine lyase
MLOALDAC_02943 6.9e-238 lmrB EGP the major facilitator superfamily
MLOALDAC_02944 2.7e-100 yxaF K Transcriptional regulator
MLOALDAC_02945 1.7e-199 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MLOALDAC_02946 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MLOALDAC_02947 1.4e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
MLOALDAC_02948 4.3e-172 yccK C Aldo keto reductase
MLOALDAC_02949 6.2e-177 ycdA S Domain of unknown function (DUF5105)
MLOALDAC_02950 1e-262 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MLOALDAC_02951 3.9e-267 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MLOALDAC_02952 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
MLOALDAC_02953 9.3e-190 S response regulator aspartate phosphatase
MLOALDAC_02954 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
MLOALDAC_02955 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MLOALDAC_02956 2.3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
MLOALDAC_02957 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MLOALDAC_02958 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MLOALDAC_02959 1.2e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLOALDAC_02960 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MLOALDAC_02961 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
MLOALDAC_02962 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
MLOALDAC_02963 9.7e-138 terC P Protein of unknown function (DUF475)
MLOALDAC_02964 0.0 yceG S Putative component of 'biosynthetic module'
MLOALDAC_02965 5.1e-193 yceH P Belongs to the TelA family
MLOALDAC_02966 2.1e-216 naiP P Uncharacterised MFS-type transporter YbfB
MLOALDAC_02967 3.9e-229 proV 3.6.3.32 E glycine betaine
MLOALDAC_02968 1.6e-138 opuAB P glycine betaine
MLOALDAC_02969 3.1e-164 opuAC E glycine betaine
MLOALDAC_02970 1.7e-212 amhX S amidohydrolase
MLOALDAC_02971 1.1e-230 ycgA S Membrane
MLOALDAC_02972 6.3e-82 ycgB
MLOALDAC_02973 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MLOALDAC_02974 4.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MLOALDAC_02976 2.3e-42
MLOALDAC_02979 6.5e-62 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
MLOALDAC_02981 5.3e-28 cobT 1.13.11.79, 2.4.2.21 C coenzyme F420-1:gamma-L-glutamate ligase activity
MLOALDAC_02982 1.9e-16 C Nitroreductase
MLOALDAC_02984 5.2e-48 V COG1131 ABC-type multidrug transport system, ATPase component
MLOALDAC_02985 1.8e-19 V ABC-2 type transporter
MLOALDAC_02986 6.2e-261 mdr EGP Major facilitator Superfamily
MLOALDAC_02987 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
MLOALDAC_02988 4.7e-114 ycgF E Lysine exporter protein LysE YggA
MLOALDAC_02989 1.7e-150 yqcI S YqcI/YcgG family
MLOALDAC_02990 2.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MLOALDAC_02991 7.6e-114 ycgI S Domain of unknown function (DUF1989)
MLOALDAC_02992 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MLOALDAC_02994 1.5e-138 4.2.1.118 G Xylose isomerase-like TIM barrel
MLOALDAC_02995 1.8e-232 G COG0477 Permeases of the major facilitator superfamily
MLOALDAC_02996 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MLOALDAC_02997 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MLOALDAC_02998 1.5e-146 ycgL S Predicted nucleotidyltransferase
MLOALDAC_02999 2.3e-170 ycgM E Proline dehydrogenase
MLOALDAC_03000 5.2e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MLOALDAC_03001 1.7e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLOALDAC_03002 2.8e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MLOALDAC_03003 6.4e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MLOALDAC_03004 6e-282 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MLOALDAC_03005 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
MLOALDAC_03006 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MLOALDAC_03007 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MLOALDAC_03008 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MLOALDAC_03009 2e-222 nasA P COG2223 Nitrate nitrite transporter
MLOALDAC_03010 1.9e-228 yciC S GTPases (G3E family)
MLOALDAC_03011 4.6e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MLOALDAC_03012 2.8e-73 yckC S membrane
MLOALDAC_03013 8.4e-51 S Protein of unknown function (DUF2680)
MLOALDAC_03014 1.6e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MLOALDAC_03015 1e-66 nin S Competence protein J (ComJ)
MLOALDAC_03016 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
MLOALDAC_03017 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MLOALDAC_03018 1.1e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MLOALDAC_03019 6.3e-63 hxlR K transcriptional
MLOALDAC_03020 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_03021 1.2e-70 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_03022 1.8e-253 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_03023 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MLOALDAC_03024 1.5e-140 srfAD Q thioesterase
MLOALDAC_03025 1.6e-249 bamJ E Aminotransferase class I and II
MLOALDAC_03026 1e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MLOALDAC_03027 1.3e-111 yczE S membrane
MLOALDAC_03028 1.4e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MLOALDAC_03029 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
MLOALDAC_03030 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MLOALDAC_03031 1.1e-158 bsdA K LysR substrate binding domain
MLOALDAC_03032 2.1e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MLOALDAC_03033 2.4e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MLOALDAC_03034 2e-38 bsdD 4.1.1.61 S response to toxic substance
MLOALDAC_03035 1.2e-77 yclD
MLOALDAC_03036 8.5e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MLOALDAC_03037 5.9e-49
MLOALDAC_03038 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MLOALDAC_03039 5.4e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLOALDAC_03040 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLOALDAC_03041 1.3e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLOALDAC_03042 2.9e-221 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MLOALDAC_03043 3e-251 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLOALDAC_03044 1.3e-257 tuaE M Teichuronic acid biosynthesis protein
MLOALDAC_03045 3.5e-115 tuaF M protein involved in exopolysaccharide biosynthesis
MLOALDAC_03046 6.8e-144 tuaG GT2 M Glycosyltransferase like family 2
MLOALDAC_03047 8e-240 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MLOALDAC_03048 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MLOALDAC_03049 3e-173 yvhJ K Transcriptional regulator
MLOALDAC_03050 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MLOALDAC_03051 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MLOALDAC_03052 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLOALDAC_03053 5.5e-158 degV S protein conserved in bacteria
MLOALDAC_03054 3.3e-261 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MLOALDAC_03055 1.5e-43 comFB S Late competence development protein ComFB
MLOALDAC_03056 1.6e-77 comFC S Phosphoribosyl transferase domain
MLOALDAC_03057 1.4e-74 yvyF S flagellar protein
MLOALDAC_03058 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
MLOALDAC_03059 8.9e-81 flgN NOU FlgN protein
MLOALDAC_03060 2.8e-274 flgK N flagellar hook-associated protein
MLOALDAC_03061 2.3e-162 flgL N Belongs to the bacterial flagellin family
MLOALDAC_03062 1.2e-79 yviE
MLOALDAC_03063 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MLOALDAC_03064 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MLOALDAC_03065 4.2e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLOALDAC_03066 5.2e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MLOALDAC_03067 3e-66 fliS N flagellar protein FliS
MLOALDAC_03068 2.6e-10 fliT S bacterial-type flagellum organization
MLOALDAC_03069 6.8e-68
MLOALDAC_03070 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLOALDAC_03071 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MLOALDAC_03072 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MLOALDAC_03073 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MLOALDAC_03074 6.2e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
MLOALDAC_03075 1e-122 ftsE D cell division ATP-binding protein FtsE
MLOALDAC_03076 2.7e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MLOALDAC_03077 4.1e-227 ywoF P Right handed beta helix region
MLOALDAC_03078 4.6e-255 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MLOALDAC_03079 3.4e-55 swrA S Swarming motility protein
MLOALDAC_03080 2.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLOALDAC_03081 5.1e-177 S Psort location CytoplasmicMembrane, score
MLOALDAC_03083 1e-26 bacT Q Thioesterase domain
MLOALDAC_03084 3e-227 yvkA EGP Major facilitator Superfamily
MLOALDAC_03085 2.4e-110 yvkB K Transcriptional regulator
MLOALDAC_03086 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MLOALDAC_03087 7.6e-33 csbA S protein conserved in bacteria
MLOALDAC_03088 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MLOALDAC_03089 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MLOALDAC_03090 3e-38 yvkN
MLOALDAC_03091 6.1e-49 yvlA
MLOALDAC_03092 3.2e-166 yvlB S Putative adhesin
MLOALDAC_03093 1.3e-25 pspB KT PspC domain
MLOALDAC_03094 3.9e-41 yvlD S Membrane
MLOALDAC_03095 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MLOALDAC_03096 6.2e-105 yxaF K Transcriptional regulator
MLOALDAC_03097 1.2e-132 yvoA K transcriptional
MLOALDAC_03098 1.2e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MLOALDAC_03099 1.5e-225 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLOALDAC_03100 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLOALDAC_03101 2.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLOALDAC_03102 4.8e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MLOALDAC_03103 5.4e-84 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MLOALDAC_03104 1.8e-138 yvpB NU protein conserved in bacteria
MLOALDAC_03105 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MLOALDAC_03106 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MLOALDAC_03107 1.2e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MLOALDAC_03108 2e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MLOALDAC_03109 9.6e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MLOALDAC_03110 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MLOALDAC_03111 3.1e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MLOALDAC_03112 3.7e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MLOALDAC_03113 0.0 msbA2 3.6.3.44 V ABC transporter
MLOALDAC_03114 1e-57
MLOALDAC_03115 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_03116 7.2e-192 sasA T Histidine kinase
MLOALDAC_03117 2.9e-276 S COG0457 FOG TPR repeat
MLOALDAC_03118 2.1e-122 usp CBM50 M protein conserved in bacteria
MLOALDAC_03119 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MLOALDAC_03120 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MLOALDAC_03121 1.1e-166 rapZ S Displays ATPase and GTPase activities
MLOALDAC_03122 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MLOALDAC_03123 3.1e-170 whiA K May be required for sporulation
MLOALDAC_03124 4.7e-36 crh G Phosphocarrier protein Chr
MLOALDAC_03125 1.3e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MLOALDAC_03126 1.6e-79 M Ribonuclease
MLOALDAC_03127 7.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLOALDAC_03128 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MLOALDAC_03129 5.6e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MLOALDAC_03130 4.4e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
MLOALDAC_03131 2.1e-105 yvdD 3.2.2.10 S Belongs to the LOG family
MLOALDAC_03132 4e-251 EGP Sugar (and other) transporter
MLOALDAC_03133 2.1e-213 yraM S PrpF protein
MLOALDAC_03134 1.3e-162 yraN K Transcriptional regulator
MLOALDAC_03135 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MLOALDAC_03136 1.6e-182 scrR K transcriptional
MLOALDAC_03137 1.2e-219 rafB P LacY proton/sugar symporter
MLOALDAC_03138 1.5e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
MLOALDAC_03140 3.1e-34
MLOALDAC_03141 6.6e-241 I Pfam Lipase (class 3)
MLOALDAC_03142 7.1e-25 S Protein of unknown function (DUF1433)
MLOALDAC_03143 5.7e-20 S Protein of unknown function (DUF1433)
MLOALDAC_03144 6.3e-13 S Protein of unknown function (DUF1433)
MLOALDAC_03145 1.2e-12 MA20_18690 S Protein of unknown function (DUF3237)
MLOALDAC_03146 1.6e-93 padC Q Phenolic acid decarboxylase
MLOALDAC_03147 8.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLOALDAC_03148 2.8e-111 yyaS S Membrane
MLOALDAC_03149 8.3e-96 ywjB H RibD C-terminal domain
MLOALDAC_03151 1.1e-275 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MLOALDAC_03152 1.9e-77 slr K transcriptional
MLOALDAC_03153 8.4e-120 ywqC M biosynthesis protein
MLOALDAC_03154 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MLOALDAC_03155 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MLOALDAC_03156 1.1e-217 epsD GT4 M Glycosyl transferase 4-like
MLOALDAC_03157 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLOALDAC_03158 2.1e-213 epsF GT4 M Glycosyl transferases group 1
MLOALDAC_03159 3.5e-205 epsG S EpsG family
MLOALDAC_03160 6.8e-195 epsH GT2 S Glycosyltransferase like family 2
MLOALDAC_03161 1.7e-204 epsI GM pyruvyl transferase
MLOALDAC_03162 4.4e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MLOALDAC_03163 1.4e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLOALDAC_03164 9.8e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MLOALDAC_03165 2.7e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MLOALDAC_03166 5.3e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MLOALDAC_03167 1.4e-189 yvfF GM Exopolysaccharide biosynthesis protein
MLOALDAC_03168 2.7e-32 yvfG S YvfG protein
MLOALDAC_03169 2.6e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MLOALDAC_03170 8.4e-304 yvfH C L-lactate permease
MLOALDAC_03171 1.3e-120 yvfI K COG2186 Transcriptional regulators
MLOALDAC_03172 9.2e-220 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MLOALDAC_03173 3.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLOALDAC_03174 2.1e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MLOALDAC_03175 1.8e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MLOALDAC_03176 3.9e-25 M nucleic acid phosphodiester bond hydrolysis
MLOALDAC_03179 8.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
MLOALDAC_03180 1.2e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
MLOALDAC_03181 3.5e-152 ybbH_1 K RpiR family transcriptional regulator
MLOALDAC_03182 6.7e-167 3.1.3.104 S hydrolases of the HAD superfamily
MLOALDAC_03183 7.7e-115 yyaS S Membrane
MLOALDAC_03184 1.1e-183 purR7 5.1.1.1 K Transcriptional regulator
MLOALDAC_03185 5.3e-261
MLOALDAC_03186 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MLOALDAC_03187 1.5e-156 yvbV EG EamA-like transporter family
MLOALDAC_03188 1.1e-124 yvbU K Transcriptional regulator
MLOALDAC_03189 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLOALDAC_03190 2.9e-204 araR K transcriptional
MLOALDAC_03191 9.6e-253 araE EGP Major facilitator Superfamily
MLOALDAC_03193 6.8e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MLOALDAC_03194 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MLOALDAC_03195 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MLOALDAC_03196 1.5e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MLOALDAC_03197 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MLOALDAC_03198 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MLOALDAC_03199 8e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MLOALDAC_03200 6.2e-257 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLOALDAC_03201 1.1e-217 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MLOALDAC_03202 1.2e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
MLOALDAC_03203 5.5e-239 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MLOALDAC_03204 3.4e-150 M Protein involved in cellulose biosynthesis
MLOALDAC_03205 2.1e-142 C WbqC-like protein family
MLOALDAC_03206 9.8e-126 S GlcNAc-PI de-N-acetylase
MLOALDAC_03207 1e-178
MLOALDAC_03208 2.5e-212 EGP Major facilitator Superfamily
MLOALDAC_03209 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
MLOALDAC_03210 0.0 tcaA S response to antibiotic
MLOALDAC_03211 1.4e-114 exoY M Membrane
MLOALDAC_03212 5.2e-105 yvbG U UPF0056 membrane protein
MLOALDAC_03213 1.9e-98 yvbF K Belongs to the GbsR family
MLOALDAC_03214 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MLOALDAC_03215 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLOALDAC_03216 7.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MLOALDAC_03217 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MLOALDAC_03218 7.8e-08
MLOALDAC_03220 8.7e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MLOALDAC_03221 7e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MLOALDAC_03222 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MLOALDAC_03223 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MLOALDAC_03224 2.3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLOALDAC_03225 0.0 ydiF S ABC transporter
MLOALDAC_03226 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MLOALDAC_03227 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MLOALDAC_03228 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MLOALDAC_03229 2.7e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLOALDAC_03230 1.7e-27 ydiK S Domain of unknown function (DUF4305)
MLOALDAC_03231 2.5e-127 ydiL S CAAX protease self-immunity
MLOALDAC_03232 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLOALDAC_03233 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MLOALDAC_03234 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
MLOALDAC_03237 9.5e-65
MLOALDAC_03238 0.0 K NB-ARC domain
MLOALDAC_03239 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
MLOALDAC_03240 1.1e-248 gutA G MFS/sugar transport protein
MLOALDAC_03241 1.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MLOALDAC_03242 2.3e-29 yjdJ S Domain of unknown function (DUF4306)
MLOALDAC_03243 4.3e-113 pspA KT Phage shock protein A
MLOALDAC_03244 1.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MLOALDAC_03245 3.7e-121 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MLOALDAC_03246 1.1e-154 ydjI S virion core protein (lumpy skin disease virus)
MLOALDAC_03247 0.0 yrhL I Acyltransferase family
MLOALDAC_03248 1.2e-147 rsiV S Protein of unknown function (DUF3298)
MLOALDAC_03249 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MLOALDAC_03250 1.8e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MLOALDAC_03251 4.2e-62 ydjM M Lytic transglycolase
MLOALDAC_03252 9.7e-133 ydjN U Involved in the tonB-independent uptake of proteins
MLOALDAC_03254 7.2e-35 ydjO S Cold-inducible protein YdjO
MLOALDAC_03255 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MLOALDAC_03256 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MLOALDAC_03257 8.4e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLOALDAC_03258 4.6e-177 yeaC S COG0714 MoxR-like ATPases
MLOALDAC_03259 1.4e-215 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MLOALDAC_03260 0.0 yebA E COG1305 Transglutaminase-like enzymes
MLOALDAC_03261 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MLOALDAC_03262 3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MLOALDAC_03263 9.3e-259 S Domain of unknown function (DUF4179)
MLOALDAC_03264 6.2e-209 pbuG S permease
MLOALDAC_03265 1.9e-125 yebC M Membrane
MLOALDAC_03267 2e-92 yebE S UPF0316 protein
MLOALDAC_03268 5.5e-29 yebG S NETI protein
MLOALDAC_03269 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLOALDAC_03270 1.4e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLOALDAC_03271 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLOALDAC_03272 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MLOALDAC_03273 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLOALDAC_03274 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLOALDAC_03275 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLOALDAC_03276 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLOALDAC_03277 4.6e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MLOALDAC_03278 7e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLOALDAC_03279 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MLOALDAC_03280 1.8e-234 purD 6.3.4.13 F Belongs to the GARS family
MLOALDAC_03281 2e-25 S Protein of unknown function (DUF2892)
MLOALDAC_03282 0.0 yerA 3.5.4.2 F adenine deaminase
MLOALDAC_03283 1.4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
MLOALDAC_03284 2.4e-50 yerC S protein conserved in bacteria
MLOALDAC_03285 2.3e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MLOALDAC_03286 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MLOALDAC_03287 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MLOALDAC_03288 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLOALDAC_03289 2.3e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
MLOALDAC_03290 1.9e-194 yerI S homoserine kinase type II (protein kinase fold)
MLOALDAC_03291 4.3e-121 sapB S MgtC SapB transporter
MLOALDAC_03292 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MLOALDAC_03293 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLOALDAC_03294 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MLOALDAC_03295 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLOALDAC_03296 9.6e-155 yerO K Transcriptional regulator
MLOALDAC_03297 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLOALDAC_03298 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MLOALDAC_03299 7.6e-250 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLOALDAC_03300 7.5e-85
MLOALDAC_03301 6.3e-103 H Prokaryotic E2 family B
MLOALDAC_03302 2.7e-27 S Prokaryotic homologs of the JAB domain
MLOALDAC_03303 4.4e-78 V HNH nucleases
MLOALDAC_03304 1.9e-159 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
MLOALDAC_03305 9.3e-137 cylB V ABC-2 type transporter
MLOALDAC_03306 1.1e-62 S Protein of unknown function, DUF600
MLOALDAC_03307 1.2e-50 S Protein of unknown function, DUF600
MLOALDAC_03308 4.5e-53 S Protein of unknown function, DUF600
MLOALDAC_03309 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
MLOALDAC_03310 1.6e-16
MLOALDAC_03311 9.4e-127 yeeN K transcriptional regulatory protein
MLOALDAC_03313 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
MLOALDAC_03314 3.3e-45 cotJB S CotJB protein
MLOALDAC_03315 8.9e-104 cotJC P Spore Coat
MLOALDAC_03316 7e-95 yesJ K Acetyltransferase (GNAT) family
MLOALDAC_03318 4.3e-121 yetF S membrane
MLOALDAC_03319 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MLOALDAC_03320 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLOALDAC_03321 2.6e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MLOALDAC_03322 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
MLOALDAC_03323 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
MLOALDAC_03324 1.1e-105 yetJ S Belongs to the BI1 family
MLOALDAC_03325 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
MLOALDAC_03326 4.9e-207 yetM CH FAD binding domain
MLOALDAC_03327 7.5e-197 yetN S Protein of unknown function (DUF3900)
MLOALDAC_03328 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MLOALDAC_03330 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLOALDAC_03331 7.9e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
MLOALDAC_03332 2.4e-172 yfnG 4.2.1.45 M dehydratase
MLOALDAC_03333 2.3e-178 yfnF M Nucleotide-diphospho-sugar transferase
MLOALDAC_03334 3.3e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MLOALDAC_03335 4e-186 yfnD M Nucleotide-diphospho-sugar transferase
MLOALDAC_03336 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
MLOALDAC_03337 6.6e-246 yfnA E amino acid
MLOALDAC_03338 7.7e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MLOALDAC_03339 9.8e-115 yfmS NT chemotaxis protein
MLOALDAC_03340 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
MLOALDAC_03341 1.6e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLOALDAC_03342 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLOALDAC_03343 3.1e-69 yfmP K transcriptional
MLOALDAC_03344 2.1e-208 yfmO EGP Major facilitator Superfamily
MLOALDAC_03345 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MLOALDAC_03346 1.8e-204 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MLOALDAC_03347 9.8e-66 yfmK 2.3.1.128 K acetyltransferase
MLOALDAC_03348 2.2e-190 yfmJ S N-terminal domain of oxidoreductase
MLOALDAC_03349 1.7e-24 S Protein of unknown function (DUF3212)
MLOALDAC_03350 1.3e-57 yflT S Heat induced stress protein YflT
MLOALDAC_03351 2.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MLOALDAC_03352 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
MLOALDAC_03353 5.5e-29 Q PFAM Collagen triple helix
MLOALDAC_03359 7.8e-08
MLOALDAC_03367 1.6e-08
MLOALDAC_03371 6.1e-288 C Na+/H+ antiporter family
MLOALDAC_03372 2.8e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MLOALDAC_03373 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MLOALDAC_03374 2.6e-266 ygaK C Berberine and berberine like
MLOALDAC_03376 9.8e-231 oppA5 E PFAM extracellular solute-binding protein family 5
MLOALDAC_03377 6e-137 appB P Binding-protein-dependent transport system inner membrane component
MLOALDAC_03378 9.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLOALDAC_03379 1.3e-134 oppD3 P Belongs to the ABC transporter superfamily
MLOALDAC_03380 6.2e-134 oppF3 E Belongs to the ABC transporter superfamily
MLOALDAC_03381 1e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MLOALDAC_03382 1.7e-184 S Amidohydrolase
MLOALDAC_03383 4.2e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MLOALDAC_03384 1.1e-181 ssuA M Sulfonate ABC transporter
MLOALDAC_03385 4e-145 ssuC P ABC transporter (permease)
MLOALDAC_03386 8.5e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MLOALDAC_03387 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLOALDAC_03388 6.6e-81 ygaO
MLOALDAC_03389 1.4e-22 K Transcriptional regulator
MLOALDAC_03391 7.9e-114 yhzB S B3/4 domain
MLOALDAC_03392 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MLOALDAC_03393 1.1e-175 yhbB S Putative amidase domain
MLOALDAC_03394 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MLOALDAC_03395 1e-108 yhbD K Protein of unknown function (DUF4004)
MLOALDAC_03396 8.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MLOALDAC_03397 1.3e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MLOALDAC_03399 0.0 prkA T Ser protein kinase
MLOALDAC_03400 2.7e-216 yhbH S Belongs to the UPF0229 family
MLOALDAC_03401 4.6e-74 yhbI K DNA-binding transcription factor activity
MLOALDAC_03402 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
MLOALDAC_03403 8.4e-285 yhcA EGP Major facilitator Superfamily
MLOALDAC_03404 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
MLOALDAC_03405 3.8e-55 yhcC
MLOALDAC_03406 3.3e-53
MLOALDAC_03407 2.5e-62 yhcF K Transcriptional regulator
MLOALDAC_03408 3e-125 yhcG V ABC transporter, ATP-binding protein
MLOALDAC_03409 4.1e-167 yhcH V ABC transporter, ATP-binding protein
MLOALDAC_03410 1.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MLOALDAC_03411 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
MLOALDAC_03412 3.7e-117 metQ M Belongs to the nlpA lipoprotein family
MLOALDAC_03413 1e-193 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MLOALDAC_03414 1.1e-221 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MLOALDAC_03415 4.2e-54 yhcM
MLOALDAC_03416 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MLOALDAC_03417 1.2e-160 yhcP
MLOALDAC_03418 5.8e-115 yhcQ M Spore coat protein
MLOALDAC_03419 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
MLOALDAC_03420 1.8e-107 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MLOALDAC_03421 3.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MLOALDAC_03422 8.4e-69 yhcU S Family of unknown function (DUF5365)
MLOALDAC_03423 2.6e-68 yhcV S COG0517 FOG CBS domain
MLOALDAC_03424 4.9e-125 yhcW 5.4.2.6 S hydrolase
MLOALDAC_03425 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MLOALDAC_03426 4.2e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLOALDAC_03427 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MLOALDAC_03428 3.5e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MLOALDAC_03429 7e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLOALDAC_03430 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MLOALDAC_03431 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MLOALDAC_03432 9.4e-206 yhcY 2.7.13.3 T Histidine kinase
MLOALDAC_03433 5.9e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MLOALDAC_03434 8.8e-90 azr 1.7.1.6 S NADPH-dependent FMN reductase
MLOALDAC_03435 2.5e-39 yhdB S YhdB-like protein
MLOALDAC_03436 4e-53 yhdC S Protein of unknown function (DUF3889)
MLOALDAC_03437 1.7e-212 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLOALDAC_03438 5.6e-74 nsrR K Transcriptional regulator
MLOALDAC_03439 1e-255 ygxB M Conserved TM helix
MLOALDAC_03440 1.2e-271 ycgB S Stage V sporulation protein R
MLOALDAC_03441 3.4e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MLOALDAC_03442 4.8e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MLOALDAC_03443 9e-164 citR K Transcriptional regulator
MLOALDAC_03444 8.3e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
MLOALDAC_03445 5.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLOALDAC_03446 6.9e-251 yhdG E amino acid
MLOALDAC_03447 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MLOALDAC_03448 8.1e-45 yhdK S Sigma-M inhibitor protein
MLOALDAC_03449 1.3e-201 yhdL S Sigma factor regulator N-terminal
MLOALDAC_03450 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MLOALDAC_03451 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MLOALDAC_03452 2.8e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MLOALDAC_03453 4.3e-71 cueR K transcriptional
MLOALDAC_03454 2.5e-225 yhdR 2.6.1.1 E Aminotransferase
MLOALDAC_03455 5.6e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MLOALDAC_03456 3.5e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MLOALDAC_03457 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLOALDAC_03458 2.8e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLOALDAC_03459 3.8e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MLOALDAC_03461 1.6e-205 yhdY M Mechanosensitive ion channel
MLOALDAC_03462 4.5e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MLOALDAC_03463 1e-156 yheN G deacetylase
MLOALDAC_03464 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MLOALDAC_03465 4.6e-88 pksA K Transcriptional regulator
MLOALDAC_03466 1.2e-94 ymcC S Membrane
MLOALDAC_03467 2.1e-85 T universal stress protein
MLOALDAC_03469 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLOALDAC_03470 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLOALDAC_03471 2.1e-111 yheG GM NAD(P)H-binding
MLOALDAC_03473 5.8e-29 sspB S spore protein
MLOALDAC_03474 1.7e-36 yheE S Family of unknown function (DUF5342)
MLOALDAC_03475 2.5e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MLOALDAC_03476 4.8e-215 yheC HJ YheC/D like ATP-grasp
MLOALDAC_03477 4.2e-206 yheB S Belongs to the UPF0754 family
MLOALDAC_03478 9.8e-53 yheA S Belongs to the UPF0342 family
MLOALDAC_03479 1.4e-204 yhaZ L DNA alkylation repair enzyme
MLOALDAC_03480 3.3e-158 yhaX S haloacid dehalogenase-like hydrolase
MLOALDAC_03481 3.5e-293 hemZ H coproporphyrinogen III oxidase
MLOALDAC_03482 2.3e-248 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
MLOALDAC_03483 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MLOALDAC_03484 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MLOALDAC_03486 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
MLOALDAC_03487 2.8e-14 S YhzD-like protein
MLOALDAC_03488 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
MLOALDAC_03489 6.1e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MLOALDAC_03490 2.6e-238 yhaO L DNA repair exonuclease
MLOALDAC_03491 0.0 yhaN L AAA domain
MLOALDAC_03492 9e-178 yhaM L Shows a 3'-5' exoribonuclease activity
MLOALDAC_03493 1.6e-32 yhaL S Sporulation protein YhaL
MLOALDAC_03494 8.2e-165 ygxA S Nucleotidyltransferase-like
MLOALDAC_03495 1.5e-56 ygzB S UPF0295 protein
MLOALDAC_03496 1.8e-80 perR P Belongs to the Fur family
MLOALDAC_03497 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
MLOALDAC_03498 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MLOALDAC_03499 3.2e-179 ygaE S Membrane
MLOALDAC_03500 2.5e-306 ygaD V ABC transporter
MLOALDAC_03501 2.2e-104 ygaC J Belongs to the UPF0374 family
MLOALDAC_03502 3.3e-37 ygaB S YgaB-like protein
MLOALDAC_03504 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MLOALDAC_03505 8.2e-37 yfhS
MLOALDAC_03506 2.7e-210 mutY L A G-specific
MLOALDAC_03507 1.4e-184 yfhP S membrane-bound metal-dependent
MLOALDAC_03508 0.0 yfhO S Bacterial membrane protein YfhO
MLOALDAC_03509 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MLOALDAC_03510 1.7e-170 yfhM S Alpha/beta hydrolase family
MLOALDAC_03511 8.8e-35 yfhL S SdpI/YhfL protein family
MLOALDAC_03512 4.5e-94 batE T Bacterial SH3 domain homologues
MLOALDAC_03513 2.2e-44 yfhJ S WVELL protein
MLOALDAC_03514 4.8e-168 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MLOALDAC_03516 2.6e-206 yfhI EGP Major facilitator Superfamily
MLOALDAC_03517 8.8e-53 yfhH S Protein of unknown function (DUF1811)
MLOALDAC_03518 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MLOALDAC_03519 1.8e-167 yfhF S nucleoside-diphosphate sugar epimerase
MLOALDAC_03521 2.1e-25 yfhD S YfhD-like protein
MLOALDAC_03522 3.3e-106 yfhC C nitroreductase
MLOALDAC_03523 6.7e-167 yfhB 5.3.3.17 S PhzF family
MLOALDAC_03524 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MLOALDAC_03525 2.8e-82 yfiV K transcriptional
MLOALDAC_03526 3e-290 yfiU EGP Major facilitator Superfamily
MLOALDAC_03527 1.8e-98 yfiT S Belongs to the metal hydrolase YfiT family
MLOALDAC_03528 1.3e-44 yrdF K ribonuclease inhibitor
MLOALDAC_03529 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
MLOALDAC_03530 5.3e-182 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MLOALDAC_03531 1.9e-112 1.6.5.2 S NADPH-dependent FMN reductase
MLOALDAC_03532 1.7e-96 padR K transcriptional
MLOALDAC_03533 8.5e-168 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MLOALDAC_03534 5.9e-160 yfiE 1.13.11.2 S glyoxalase
MLOALDAC_03535 7e-63 mhqP S DoxX
MLOALDAC_03536 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MLOALDAC_03537 0.0 yfiB3 V ABC transporter
MLOALDAC_03538 8.3e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLOALDAC_03539 1.1e-138 glvR F Helix-turn-helix domain, rpiR family
MLOALDAC_03540 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MLOALDAC_03541 7.2e-15 sspH S Belongs to the SspH family
MLOALDAC_03542 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MLOALDAC_03543 6e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MLOALDAC_03544 1.8e-215 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MLOALDAC_03545 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MLOALDAC_03546 2.2e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MLOALDAC_03547 1.4e-89 yfjM S Psort location Cytoplasmic, score
MLOALDAC_03548 3.7e-190 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLOALDAC_03549 7.8e-51 S YfzA-like protein
MLOALDAC_03550 6.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLOALDAC_03551 2.6e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MLOALDAC_03552 1.7e-184 corA P Mediates influx of magnesium ions
MLOALDAC_03553 1.5e-33
MLOALDAC_03554 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MLOALDAC_03555 9e-155 pdaA G deacetylase
MLOALDAC_03556 4.9e-27 yfjT
MLOALDAC_03557 6e-221 yfkA S YfkB-like domain
MLOALDAC_03558 3.3e-147 yfkC M Mechanosensitive ion channel
MLOALDAC_03559 2.5e-144 yfkD S YfkD-like protein
MLOALDAC_03560 1.3e-185 cax P COG0387 Ca2 H antiporter
MLOALDAC_03561 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MLOALDAC_03562 2.5e-07
MLOALDAC_03563 1.5e-144 yihY S Belongs to the UPF0761 family
MLOALDAC_03564 3.5e-52 yfkI S gas vesicle protein
MLOALDAC_03565 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLOALDAC_03566 2.7e-29 yfkK S Belongs to the UPF0435 family
MLOALDAC_03567 3.6e-192 ydiM EGP Major facilitator Superfamily
MLOALDAC_03568 1.4e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MLOALDAC_03569 2.2e-162 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLOALDAC_03570 5.8e-186 K helix_turn _helix lactose operon repressor
MLOALDAC_03571 1e-90 yfkM 1.11.1.6, 3.5.1.124 S protease
MLOALDAC_03572 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MLOALDAC_03573 4.1e-201 yibE S YibE/F-like protein
MLOALDAC_03574 4.2e-125 yibF S YibE/F-like protein
MLOALDAC_03575 1.2e-123 yfkO C nitroreductase
MLOALDAC_03576 9e-130 treR K transcriptional
MLOALDAC_03577 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MLOALDAC_03578 1.6e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MLOALDAC_03579 1.5e-37 ydgB S Spore germination protein gerPA/gerPF
MLOALDAC_03580 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
MLOALDAC_03581 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
MLOALDAC_03582 6.6e-63 yhdN S Domain of unknown function (DUF1992)
MLOALDAC_03583 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MLOALDAC_03584 6.3e-73 yfmQ S Uncharacterised protein from bacillus cereus group
MLOALDAC_03585 8.7e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MLOALDAC_03586 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
MLOALDAC_03587 2e-49 yflH S Protein of unknown function (DUF3243)
MLOALDAC_03588 7e-19 yflI
MLOALDAC_03589 1.5e-14 yflJ S Protein of unknown function (DUF2639)
MLOALDAC_03590 4.4e-123 yflK S protein conserved in bacteria
MLOALDAC_03591 2.2e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MLOALDAC_03592 1.1e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MLOALDAC_03593 2.5e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MLOALDAC_03594 7.2e-226 citM C Citrate transporter
MLOALDAC_03595 3.5e-177 yflP S Tripartite tricarboxylate transporter family receptor
MLOALDAC_03596 1.2e-118 citT T response regulator
MLOALDAC_03597 2.1e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MLOALDAC_03598 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
MLOALDAC_03599 3.3e-23 M1-820 Q Collagen triple helix repeat (20 copies)
MLOALDAC_03602 1e-49 Q calcium- and calmodulin-responsive adenylate cyclase activity
MLOALDAC_03603 0.0 pksJ Q Polyketide synthase of type I
MLOALDAC_03604 0.0 pfaA Q Polyketide synthase of type I
MLOALDAC_03605 0.0 Q Polyketide synthase of type I
MLOALDAC_03606 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MLOALDAC_03607 5.8e-219 eryK 1.14.13.154 C Cytochrome P450
MLOALDAC_03608 2.9e-240 pksG 2.3.3.10 I synthase
MLOALDAC_03609 4e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
MLOALDAC_03610 2.1e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLOALDAC_03611 2.9e-176 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MLOALDAC_03612 1.5e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MLOALDAC_03613 1e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MLOALDAC_03614 5.9e-177 coaA 2.7.1.33 F Pantothenic acid kinase
MLOALDAC_03615 2.5e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MLOALDAC_03617 2.1e-186 yueF S transporter activity
MLOALDAC_03619 1.2e-58 S YolD-like protein
MLOALDAC_03620 7.2e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLOALDAC_03621 3.9e-89 yqjY K acetyltransferase
MLOALDAC_03622 3.6e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MLOALDAC_03623 4.1e-178 yqkA K GrpB protein
MLOALDAC_03624 1.1e-59 yqkB S Belongs to the HesB IscA family
MLOALDAC_03625 7.2e-39 yqkC S Protein of unknown function (DUF2552)
MLOALDAC_03626 3.3e-177 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MLOALDAC_03628 2.2e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MLOALDAC_03630 3.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MLOALDAC_03631 2.1e-221 yqxK 3.6.4.12 L DNA helicase
MLOALDAC_03632 3e-57 ansR K Transcriptional regulator
MLOALDAC_03633 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
MLOALDAC_03634 1.4e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MLOALDAC_03635 2.7e-239 mleN C Na H antiporter
MLOALDAC_03636 2.2e-243 mleA 1.1.1.38 C malic enzyme
MLOALDAC_03637 5.7e-22
MLOALDAC_03638 3.8e-28 yqkK
MLOALDAC_03639 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MLOALDAC_03640 1.9e-80 fur P Belongs to the Fur family
MLOALDAC_03641 6.4e-37 S Protein of unknown function (DUF4227)
MLOALDAC_03642 1.7e-165 xerD L recombinase XerD
MLOALDAC_03643 1e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MLOALDAC_03644 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MLOALDAC_03645 4.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MLOALDAC_03646 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MLOALDAC_03647 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MLOALDAC_03648 5.9e-135 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLOALDAC_03649 3.7e-111 spoVAA S Stage V sporulation protein AA
MLOALDAC_03650 3.9e-60 spoVAB S Stage V sporulation protein AB
MLOALDAC_03651 1.3e-78 spoVAC S stage V sporulation protein AC
MLOALDAC_03652 5e-190 spoVAD I Stage V sporulation protein AD
MLOALDAC_03653 3.8e-57 spoVAEB S stage V sporulation protein
MLOALDAC_03654 8.8e-110 spoVAEA S stage V sporulation protein
MLOALDAC_03655 1.4e-270 spoVAF EG Stage V sporulation protein AF
MLOALDAC_03656 4e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MLOALDAC_03657 9.2e-156 ypuA S Secreted protein
MLOALDAC_03658 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MLOALDAC_03659 8.2e-82 ccdC1 O Protein of unknown function (DUF1453)
MLOALDAC_03660 4.5e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MLOALDAC_03661 1.7e-49 ypuD
MLOALDAC_03662 4.7e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLOALDAC_03663 1e-111 ribE 2.5.1.9 H Riboflavin synthase
MLOALDAC_03664 5.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLOALDAC_03665 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MLOALDAC_03666 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MLOALDAC_03667 6.4e-93 ypuF S Domain of unknown function (DUF309)
MLOALDAC_03669 1.1e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLOALDAC_03670 3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLOALDAC_03671 1.3e-93 ypuI S Protein of unknown function (DUF3907)
MLOALDAC_03672 5e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MLOALDAC_03673 2e-103 spmA S Spore maturation protein
MLOALDAC_03674 1.3e-88 spmB S Spore maturation protein
MLOALDAC_03675 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MLOALDAC_03676 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MLOALDAC_03677 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MLOALDAC_03678 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MLOALDAC_03679 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MLOALDAC_03680 0.0 resE 2.7.13.3 T Histidine kinase
MLOALDAC_03681 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MLOALDAC_03682 3.7e-199 rsiX
MLOALDAC_03683 2.8e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLOALDAC_03684 1.4e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MLOALDAC_03685 8.4e-134 pdaB 3.5.1.104 G Polysaccharide deacetylase
MLOALDAC_03686 1.7e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MLOALDAC_03687 7.6e-76 gerD
MLOALDAC_03688 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MLOALDAC_03689 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MLOALDAC_03690 1.7e-78 ybaK S Protein of unknown function (DUF2521)
MLOALDAC_03691 4.2e-83 yizA S Damage-inducible protein DinB
MLOALDAC_03692 2.4e-144 ybaJ Q Methyltransferase domain
MLOALDAC_03693 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MLOALDAC_03694 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLOALDAC_03695 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MLOALDAC_03696 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLOALDAC_03697 3.6e-149 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLOALDAC_03698 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLOALDAC_03699 4.7e-58 rplQ J Ribosomal protein L17
MLOALDAC_03700 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLOALDAC_03701 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLOALDAC_03702 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLOALDAC_03703 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MLOALDAC_03704 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLOALDAC_03705 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
MLOALDAC_03706 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MLOALDAC_03707 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MLOALDAC_03708 1.1e-72 rplO J binds to the 23S rRNA
MLOALDAC_03709 1.9e-23 rpmD J Ribosomal protein L30
MLOALDAC_03710 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLOALDAC_03711 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLOALDAC_03712 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLOALDAC_03713 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLOALDAC_03714 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLOALDAC_03715 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLOALDAC_03716 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLOALDAC_03717 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLOALDAC_03718 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLOALDAC_03719 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MLOALDAC_03720 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLOALDAC_03721 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLOALDAC_03722 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLOALDAC_03723 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLOALDAC_03724 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLOALDAC_03725 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MLOALDAC_03726 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
MLOALDAC_03727 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLOALDAC_03728 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MLOALDAC_03729 3.4e-188 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MLOALDAC_03730 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLOALDAC_03731 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLOALDAC_03732 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MLOALDAC_03733 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLOALDAC_03734 2.1e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MLOALDAC_03735 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLOALDAC_03736 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLOALDAC_03737 6.3e-108 rsmC 2.1.1.172 J Methyltransferase
MLOALDAC_03738 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MLOALDAC_03739 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLOALDAC_03740 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MLOALDAC_03741 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLOALDAC_03742 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
MLOALDAC_03743 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MLOALDAC_03744 8.9e-116 sigH K Belongs to the sigma-70 factor family
MLOALDAC_03745 4.2e-89 yacP S RNA-binding protein containing a PIN domain
MLOALDAC_03746 1.8e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLOALDAC_03747 2.3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MLOALDAC_03748 6.2e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MLOALDAC_03749 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
MLOALDAC_03750 4e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLOALDAC_03751 2.6e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MLOALDAC_03752 1.9e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MLOALDAC_03753 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MLOALDAC_03754 2.9e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MLOALDAC_03755 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MLOALDAC_03756 0.0 clpC O Belongs to the ClpA ClpB family
MLOALDAC_03757 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MLOALDAC_03758 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MLOALDAC_03759 7.5e-77 ctsR K Belongs to the CtsR family
MLOALDAC_03760 2.2e-30 csfB S Inhibitor of sigma-G Gin
MLOALDAC_03761 1e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MLOALDAC_03762 1.3e-188 yaaN P Belongs to the TelA family
MLOALDAC_03763 3.1e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MLOALDAC_03764 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLOALDAC_03765 7.5e-55 yaaQ S protein conserved in bacteria
MLOALDAC_03766 1.2e-71 yaaR S protein conserved in bacteria
MLOALDAC_03767 1.3e-182 holB 2.7.7.7 L DNA polymerase III
MLOALDAC_03768 8.8e-145 yaaT S stage 0 sporulation protein
MLOALDAC_03769 7.7e-37 yabA L Involved in initiation control of chromosome replication
MLOALDAC_03770 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
MLOALDAC_03771 3.1e-47 yazA L endonuclease containing a URI domain
MLOALDAC_03772 5.8e-163 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLOALDAC_03773 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MLOALDAC_03774 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLOALDAC_03775 6.9e-144 tatD L hydrolase, TatD
MLOALDAC_03776 1.8e-232 rpfB GH23 T protein conserved in bacteria
MLOALDAC_03777 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MLOALDAC_03778 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MLOALDAC_03779 8.4e-146 yabG S peptidase
MLOALDAC_03780 7.8e-39 veg S protein conserved in bacteria
MLOALDAC_03781 2.9e-27 sspF S DNA topological change
MLOALDAC_03782 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MLOALDAC_03783 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MLOALDAC_03784 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MLOALDAC_03785 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MLOALDAC_03786 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLOALDAC_03787 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLOALDAC_03788 1e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MLOALDAC_03789 6.1e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MLOALDAC_03790 3.7e-40 yabK S Peptide ABC transporter permease
MLOALDAC_03791 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLOALDAC_03792 6.2e-91 spoVT K stage V sporulation protein
MLOALDAC_03793 2.7e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MLOALDAC_03794 7.7e-277 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MLOALDAC_03795 1.6e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MLOALDAC_03796 1.9e-49 yabP S Sporulation protein YabP
MLOALDAC_03797 1.7e-103 yabQ S spore cortex biosynthesis protein
MLOALDAC_03798 4.1e-57 divIC D Septum formation initiator
MLOALDAC_03799 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MLOALDAC_03802 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MLOALDAC_03803 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
MLOALDAC_03804 2.1e-185 KLT serine threonine protein kinase
MLOALDAC_03805 3.8e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MLOALDAC_03806 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MLOALDAC_03807 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLOALDAC_03808 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MLOALDAC_03809 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MLOALDAC_03810 2.8e-157 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MLOALDAC_03811 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MLOALDAC_03812 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLOALDAC_03813 1.8e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MLOALDAC_03814 8.5e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MLOALDAC_03815 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MLOALDAC_03816 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLOALDAC_03817 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MLOALDAC_03818 3.8e-28 yazB K transcriptional
MLOALDAC_03819 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLOALDAC_03820 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MLOALDAC_03821 0.0 Q Polyketide synthase of type I
MLOALDAC_03822 0.0 1.1.1.320 Q Polyketide synthase of type I
MLOALDAC_03823 0.0 pksJ Q Polyketide synthase of type I
MLOALDAC_03824 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
MLOALDAC_03825 3.6e-32 yaaL S Protein of unknown function (DUF2508)
MLOALDAC_03826 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLOALDAC_03827 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLOALDAC_03828 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLOALDAC_03829 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MLOALDAC_03830 2.6e-100 yaaI Q COG1335 Amidases related to nicotinamidase
MLOALDAC_03831 1.7e-211 yaaH M Glycoside Hydrolase Family
MLOALDAC_03832 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MLOALDAC_03833 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MLOALDAC_03834 1.3e-09
MLOALDAC_03835 4.9e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MLOALDAC_03836 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLOALDAC_03837 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MLOALDAC_03838 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MLOALDAC_03839 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MLOALDAC_03840 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MLOALDAC_03841 8.8e-184 yaaC S YaaC-like Protein
MLOALDAC_03842 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_03843 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_03844 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MLOALDAC_03845 3.4e-39 S COG NOG14552 non supervised orthologous group
MLOALDAC_03848 1.6e-08
MLOALDAC_03852 1.7e-07
MLOALDAC_03855 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)