ORF_ID e_value Gene_name EC_number CAZy COGs Description
KHCADADO_00001 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
KHCADADO_00002 3.4e-94 M1-753 M FR47-like protein
KHCADADO_00003 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
KHCADADO_00004 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KHCADADO_00005 3.9e-84 yuaE S DinB superfamily
KHCADADO_00006 7.9e-108 yuaD
KHCADADO_00007 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
KHCADADO_00008 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KHCADADO_00009 1.1e-95 yuaC K Belongs to the GbsR family
KHCADADO_00010 2.2e-91 yuaB
KHCADADO_00011 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
KHCADADO_00012 5.4e-237 ktrB P Potassium
KHCADADO_00013 1e-38 yiaA S yiaA/B two helix domain
KHCADADO_00014 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KHCADADO_00015 6.2e-277 yubD P Major Facilitator Superfamily
KHCADADO_00016 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
KHCADADO_00018 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KHCADADO_00019 6.3e-197 yubA S transporter activity
KHCADADO_00020 3.3e-183 ygjR S Oxidoreductase
KHCADADO_00021 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
KHCADADO_00022 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KHCADADO_00023 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KHCADADO_00024 1.8e-93 fucR K COG1349 Transcriptional regulators of sugar metabolism
KHCADADO_00025 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
KHCADADO_00026 5.1e-239 mcpA NT chemotaxis protein
KHCADADO_00027 2.2e-295 mcpA NT chemotaxis protein
KHCADADO_00028 1.5e-222 mcpA NT chemotaxis protein
KHCADADO_00029 3.2e-225 mcpA NT chemotaxis protein
KHCADADO_00030 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KHCADADO_00031 1e-35
KHCADADO_00032 2.1e-72 yugU S Uncharacterised protein family UPF0047
KHCADADO_00033 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KHCADADO_00034 2.4e-234 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KHCADADO_00035 1.4e-116 yugP S Zn-dependent protease
KHCADADO_00036 4.6e-39
KHCADADO_00037 1.1e-53 mstX S Membrane-integrating protein Mistic
KHCADADO_00038 1.7e-182 yugO P COG1226 Kef-type K transport systems
KHCADADO_00039 1.3e-72 yugN S YugN-like family
KHCADADO_00041 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
KHCADADO_00042 2.8e-229 yugK C Dehydrogenase
KHCADADO_00043 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KHCADADO_00044 1.1e-34 yuzA S Domain of unknown function (DUF378)
KHCADADO_00045 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KHCADADO_00046 4.3e-200 yugH 2.6.1.1 E Aminotransferase
KHCADADO_00047 1.6e-85 alaR K Transcriptional regulator
KHCADADO_00048 1e-156 yugF I Hydrolase
KHCADADO_00049 9.8e-42 yugE S Domain of unknown function (DUF1871)
KHCADADO_00050 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KHCADADO_00051 1.5e-137 T PhoQ Sensor
KHCADADO_00052 2e-70 kapB G Kinase associated protein B
KHCADADO_00053 1.9e-115 kapD L the KinA pathway to sporulation
KHCADADO_00055 3.5e-186 yuxJ EGP Major facilitator Superfamily
KHCADADO_00056 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KHCADADO_00057 6.3e-75 yuxK S protein conserved in bacteria
KHCADADO_00058 6.3e-78 yufK S Family of unknown function (DUF5366)
KHCADADO_00059 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KHCADADO_00060 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
KHCADADO_00061 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KHCADADO_00062 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KHCADADO_00063 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
KHCADADO_00064 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
KHCADADO_00065 1.3e-233 maeN C COG3493 Na citrate symporter
KHCADADO_00066 1.9e-14
KHCADADO_00067 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KHCADADO_00068 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KHCADADO_00069 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KHCADADO_00070 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KHCADADO_00071 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KHCADADO_00072 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KHCADADO_00073 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KHCADADO_00074 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
KHCADADO_00075 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KHCADADO_00076 8.2e-221 comP 2.7.13.3 T Histidine kinase
KHCADADO_00077 4.1e-77 comP 2.7.13.3 T Histidine kinase
KHCADADO_00078 1.1e-57 comP 2.7.13.3 T Histidine kinase
KHCADADO_00080 2.5e-162 comQ H Polyprenyl synthetase
KHCADADO_00082 1.1e-22 yuzC
KHCADADO_00083 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KHCADADO_00084 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHCADADO_00085 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
KHCADADO_00086 1.6e-67 yueI S Protein of unknown function (DUF1694)
KHCADADO_00087 7.4e-39 yueH S YueH-like protein
KHCADADO_00088 2.1e-32 yueG S Spore germination protein gerPA/gerPF
KHCADADO_00089 1.9e-190 yueF S transporter activity
KHCADADO_00090 6.1e-72 S Protein of unknown function (DUF2283)
KHCADADO_00091 2.9e-24 S Protein of unknown function (DUF2642)
KHCADADO_00092 1.6e-85 yueE S phosphohydrolase
KHCADADO_00093 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHCADADO_00094 6.6e-65 yueC S Family of unknown function (DUF5383)
KHCADADO_00095 0.0 esaA S type VII secretion protein EsaA
KHCADADO_00096 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KHCADADO_00097 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KHCADADO_00098 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
KHCADADO_00099 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
KHCADADO_00100 2.8e-45 esxA S Belongs to the WXG100 family
KHCADADO_00101 6.5e-229 yukF QT Transcriptional regulator
KHCADADO_00102 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KHCADADO_00103 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
KHCADADO_00104 3.8e-36 mbtH S MbtH-like protein
KHCADADO_00105 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_00106 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KHCADADO_00107 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KHCADADO_00108 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
KHCADADO_00109 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_00110 1.3e-167 besA S Putative esterase
KHCADADO_00111 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
KHCADADO_00112 1.1e-93 bioY S Biotin biosynthesis protein
KHCADADO_00113 3.9e-211 yuiF S antiporter
KHCADADO_00114 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KHCADADO_00115 1.2e-77 yuiD S protein conserved in bacteria
KHCADADO_00116 5.6e-118 yuiC S protein conserved in bacteria
KHCADADO_00117 8.4e-27 yuiB S Putative membrane protein
KHCADADO_00118 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
KHCADADO_00119 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
KHCADADO_00121 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHCADADO_00122 9e-118 paiB K Putative FMN-binding domain
KHCADADO_00123 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHCADADO_00124 3.7e-63 erpA S Belongs to the HesB IscA family
KHCADADO_00125 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KHCADADO_00126 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHCADADO_00127 3.2e-39 yuzB S Belongs to the UPF0349 family
KHCADADO_00128 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
KHCADADO_00129 3.5e-57 yuzD S protein conserved in bacteria
KHCADADO_00130 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KHCADADO_00131 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KHCADADO_00132 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KHCADADO_00133 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KHCADADO_00134 7.5e-211 hom 1.1.1.3 E homoserine dehydrogenase
KHCADADO_00135 5.9e-15 hom 1.1.1.3 E homoserine dehydrogenase
KHCADADO_00136 2e-199 yutH S Spore coat protein
KHCADADO_00137 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KHCADADO_00138 8.6e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KHCADADO_00139 1e-75 yutE S Protein of unknown function DUF86
KHCADADO_00140 9.7e-48 yutD S protein conserved in bacteria
KHCADADO_00141 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KHCADADO_00142 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KHCADADO_00143 4.5e-196 lytH M Peptidase, M23
KHCADADO_00144 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
KHCADADO_00145 4.8e-48 yunC S Domain of unknown function (DUF1805)
KHCADADO_00146 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KHCADADO_00147 2e-141 yunE S membrane transporter protein
KHCADADO_00148 4.3e-171 yunF S Protein of unknown function DUF72
KHCADADO_00149 3e-62 yunG
KHCADADO_00150 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KHCADADO_00151 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
KHCADADO_00152 2.1e-236 pbuX F Permease family
KHCADADO_00153 1.3e-224 pbuX F xanthine
KHCADADO_00154 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KHCADADO_00155 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KHCADADO_00156 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KHCADADO_00157 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KHCADADO_00158 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KHCADADO_00159 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KHCADADO_00160 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KHCADADO_00162 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KHCADADO_00163 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KHCADADO_00164 2.4e-169 bsn L Ribonuclease
KHCADADO_00165 1.2e-205 msmX P Belongs to the ABC transporter superfamily
KHCADADO_00166 1.1e-135 yurK K UTRA
KHCADADO_00167 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KHCADADO_00168 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
KHCADADO_00169 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
KHCADADO_00170 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KHCADADO_00171 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KHCADADO_00172 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KHCADADO_00173 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KHCADADO_00175 1e-41
KHCADADO_00176 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHCADADO_00177 3.3e-43 K helix_turn_helix, Arsenical Resistance Operon Repressor
KHCADADO_00178 3.5e-271 sufB O FeS cluster assembly
KHCADADO_00179 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KHCADADO_00180 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHCADADO_00181 1.4e-245 sufD O assembly protein SufD
KHCADADO_00182 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KHCADADO_00183 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KHCADADO_00184 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
KHCADADO_00185 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
KHCADADO_00186 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHCADADO_00187 2.4e-56 yusD S SCP-2 sterol transfer family
KHCADADO_00188 5.6e-55 traF CO Thioredoxin
KHCADADO_00189 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KHCADADO_00190 1.1e-39 yusG S Protein of unknown function (DUF2553)
KHCADADO_00191 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KHCADADO_00192 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KHCADADO_00193 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KHCADADO_00194 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
KHCADADO_00195 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KHCADADO_00196 2.2e-165 fadM E Proline dehydrogenase
KHCADADO_00197 5.1e-40
KHCADADO_00198 3.2e-53 yusN M Coat F domain
KHCADADO_00199 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
KHCADADO_00200 3.8e-293 yusP P Major facilitator superfamily
KHCADADO_00201 8.4e-66 yusQ S Tautomerase enzyme
KHCADADO_00202 1e-63 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_00203 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_00204 2.7e-160 yusT K LysR substrate binding domain
KHCADADO_00205 3.8e-47 yusU S Protein of unknown function (DUF2573)
KHCADADO_00206 1e-153 yusV 3.6.3.34 HP ABC transporter
KHCADADO_00207 5.6e-66 S YusW-like protein
KHCADADO_00208 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
KHCADADO_00209 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
KHCADADO_00210 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_00211 1.2e-79 dps P Ferritin-like domain
KHCADADO_00212 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHCADADO_00213 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_00214 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
KHCADADO_00215 3e-59 yuxN K Transcriptional regulator
KHCADADO_00216 3e-63 yuxN K Transcriptional regulator
KHCADADO_00217 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KHCADADO_00218 2.3e-24 S Protein of unknown function (DUF3970)
KHCADADO_00219 3.1e-168 gerAA EG Spore germination protein
KHCADADO_00220 9.1e-198 gerAB E Spore germination protein
KHCADADO_00221 4.6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
KHCADADO_00222 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KHCADADO_00223 5.5e-187 vraS 2.7.13.3 T Histidine kinase
KHCADADO_00224 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KHCADADO_00225 9.3e-129 liaG S Putative adhesin
KHCADADO_00226 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KHCADADO_00227 5.6e-62 liaI S membrane
KHCADADO_00228 4.8e-227 yvqJ EGP Major facilitator Superfamily
KHCADADO_00229 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
KHCADADO_00230 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KHCADADO_00231 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_00232 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KHCADADO_00233 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_00234 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
KHCADADO_00235 0.0 T PhoQ Sensor
KHCADADO_00236 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_00237 3.6e-22
KHCADADO_00238 1.8e-96 yvrI K RNA polymerase
KHCADADO_00239 2.4e-19 S YvrJ protein family
KHCADADO_00240 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
KHCADADO_00241 1.3e-64 yvrL S Regulatory protein YrvL
KHCADADO_00242 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
KHCADADO_00243 7.1e-124 macB V ABC transporter, ATP-binding protein
KHCADADO_00244 4.8e-176 M Efflux transporter rnd family, mfp subunit
KHCADADO_00245 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
KHCADADO_00246 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_00247 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_00248 2.1e-179 fhuD P ABC transporter
KHCADADO_00250 2.6e-237 yvsH E Arginine ornithine antiporter
KHCADADO_00251 5.1e-09 S Small spore protein J (Spore_SspJ)
KHCADADO_00252 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KHCADADO_00253 3.5e-149 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KHCADADO_00254 1e-153 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KHCADADO_00255 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KHCADADO_00256 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KHCADADO_00257 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
KHCADADO_00258 9.1e-158 yvgN S reductase
KHCADADO_00259 5.4e-86 yvgO
KHCADADO_00260 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KHCADADO_00261 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KHCADADO_00262 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHCADADO_00263 0.0 helD 3.6.4.12 L DNA helicase
KHCADADO_00264 4.1e-107 yvgT S membrane
KHCADADO_00265 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
KHCADADO_00266 1.6e-104 bdbD O Thioredoxin
KHCADADO_00267 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KHCADADO_00268 0.0 copA 3.6.3.54 P P-type ATPase
KHCADADO_00269 1.5e-29 copZ P Copper resistance protein CopZ
KHCADADO_00270 2.2e-48 csoR S transcriptional
KHCADADO_00271 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
KHCADADO_00272 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHCADADO_00273 0.0 yvaC S Fusaric acid resistance protein-like
KHCADADO_00274 5.7e-73 yvaD S Family of unknown function (DUF5360)
KHCADADO_00275 2.8e-55 yvaE P Small Multidrug Resistance protein
KHCADADO_00276 4.1e-101 K Bacterial regulatory proteins, tetR family
KHCADADO_00277 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_00279 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KHCADADO_00280 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KHCADADO_00281 5.6e-143 est 3.1.1.1 S Carboxylesterase
KHCADADO_00282 2.4e-23 secG U Preprotein translocase subunit SecG
KHCADADO_00283 3.7e-153 yvaM S Serine aminopeptidase, S33
KHCADADO_00284 7.5e-36 yvzC K Transcriptional
KHCADADO_00285 4e-69 K transcriptional
KHCADADO_00286 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
KHCADADO_00287 2.2e-54 yodB K transcriptional
KHCADADO_00288 4.2e-226 NT chemotaxis protein
KHCADADO_00289 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KHCADADO_00290 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KHCADADO_00291 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KHCADADO_00292 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KHCADADO_00293 8.7e-61 yvbF K Belongs to the GbsR family
KHCADADO_00294 7.6e-172
KHCADADO_00295 4.4e-08
KHCADADO_00296 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
KHCADADO_00297 4.5e-45 sdpR K transcriptional
KHCADADO_00298 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KHCADADO_00299 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KHCADADO_00300 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KHCADADO_00301 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KHCADADO_00302 1.4e-98 yvbF K Belongs to the GbsR family
KHCADADO_00303 6.4e-103 yvbG U UPF0056 membrane protein
KHCADADO_00304 8.6e-113 yvbH S YvbH-like oligomerisation region
KHCADADO_00305 4.2e-124 exoY M Membrane
KHCADADO_00306 0.0 tcaA S response to antibiotic
KHCADADO_00307 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
KHCADADO_00308 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHCADADO_00309 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KHCADADO_00310 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHCADADO_00311 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KHCADADO_00312 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHCADADO_00313 5.7e-172 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KHCADADO_00314 1.6e-252 araE EGP Major facilitator Superfamily
KHCADADO_00315 5.5e-203 araR K transcriptional
KHCADADO_00316 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHCADADO_00317 3.9e-159 yvbU K Transcriptional regulator
KHCADADO_00318 8.5e-157 yvbV EG EamA-like transporter family
KHCADADO_00319 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KHCADADO_00320 4.3e-197 yvbX S Glycosyl hydrolase
KHCADADO_00321 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KHCADADO_00322 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KHCADADO_00323 2.3e-101 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KHCADADO_00324 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KHCADADO_00325 8.9e-201 desK 2.7.13.3 T Histidine kinase
KHCADADO_00326 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
KHCADADO_00327 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
KHCADADO_00328 2.6e-157 rsbQ S Alpha/beta hydrolase family
KHCADADO_00329 1.4e-199 rsbU 3.1.3.3 T response regulator
KHCADADO_00330 2.6e-252 galA 3.2.1.89 G arabinogalactan
KHCADADO_00331 0.0 lacA 3.2.1.23 G beta-galactosidase
KHCADADO_00332 3.2e-150 ganQ P transport
KHCADADO_00333 1.3e-122 malC P COG1175 ABC-type sugar transport systems, permease components
KHCADADO_00334 1e-96 malC P COG1175 ABC-type sugar transport systems, permease components
KHCADADO_00335 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
KHCADADO_00336 1.8e-184 lacR K Transcriptional regulator
KHCADADO_00337 6.6e-111 yvfI K COG2186 Transcriptional regulators
KHCADADO_00338 2.3e-100 yvfH C L-lactate permease
KHCADADO_00339 4.7e-188 yvfH C L-lactate permease
KHCADADO_00340 1e-113 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KHCADADO_00341 1.7e-94 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KHCADADO_00342 1e-31 yvfG S YvfG protein
KHCADADO_00343 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
KHCADADO_00344 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KHCADADO_00345 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KHCADADO_00346 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KHCADADO_00347 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KHCADADO_00348 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KHCADADO_00349 3.6e-207 epsI GM pyruvyl transferase
KHCADADO_00350 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
KHCADADO_00351 4.8e-207 epsG S EpsG family
KHCADADO_00352 4e-220 epsF GT4 M Glycosyl transferases group 1
KHCADADO_00353 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KHCADADO_00354 2e-224 epsD GT4 M Glycosyl transferase 4-like
KHCADADO_00355 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KHCADADO_00356 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KHCADADO_00357 4e-122 ywqC M biosynthesis protein
KHCADADO_00358 5.7e-77 slr K transcriptional
KHCADADO_00359 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KHCADADO_00361 4.6e-93 padC Q Phenolic acid decarboxylase
KHCADADO_00362 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
KHCADADO_00363 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KHCADADO_00364 9.6e-266 pbpE V Beta-lactamase
KHCADADO_00365 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
KHCADADO_00366 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KHCADADO_00367 1.8e-295 yveA E amino acid
KHCADADO_00368 2.6e-106 yvdT K Transcriptional regulator
KHCADADO_00369 6.7e-51 ykkC P Small Multidrug Resistance protein
KHCADADO_00370 4.1e-50 sugE P Small Multidrug Resistance protein
KHCADADO_00371 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
KHCADADO_00372 9.2e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
KHCADADO_00373 1.5e-183 S Patatin-like phospholipase
KHCADADO_00375 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHCADADO_00376 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KHCADADO_00377 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KHCADADO_00378 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KHCADADO_00379 1.2e-158 malA S Protein of unknown function (DUF1189)
KHCADADO_00380 7.8e-149 malD P transport
KHCADADO_00381 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
KHCADADO_00382 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KHCADADO_00383 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KHCADADO_00384 3.6e-174 yvdE K Transcriptional regulator
KHCADADO_00385 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KHCADADO_00386 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
KHCADADO_00387 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KHCADADO_00388 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KHCADADO_00389 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHCADADO_00390 0.0 yxdM V ABC transporter (permease)
KHCADADO_00391 5.6e-141 yvcR V ABC transporter, ATP-binding protein
KHCADADO_00392 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KHCADADO_00393 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_00394 1.8e-33
KHCADADO_00395 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KHCADADO_00396 1.6e-36 crh G Phosphocarrier protein Chr
KHCADADO_00397 1.4e-170 whiA K May be required for sporulation
KHCADADO_00398 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KHCADADO_00399 5.7e-166 rapZ S Displays ATPase and GTPase activities
KHCADADO_00400 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KHCADADO_00401 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHCADADO_00402 1.4e-102 usp CBM50 M protein conserved in bacteria
KHCADADO_00403 2.4e-278 S COG0457 FOG TPR repeat
KHCADADO_00404 0.0 msbA2 3.6.3.44 V ABC transporter
KHCADADO_00406 0.0
KHCADADO_00407 4.6e-121
KHCADADO_00408 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KHCADADO_00409 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KHCADADO_00410 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KHCADADO_00411 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KHCADADO_00412 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KHCADADO_00413 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHCADADO_00414 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KHCADADO_00415 4.8e-196 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KHCADADO_00417 4.5e-140 yvpB NU protein conserved in bacteria
KHCADADO_00418 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
KHCADADO_00419 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KHCADADO_00420 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KHCADADO_00421 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
KHCADADO_00422 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHCADADO_00423 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHCADADO_00424 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHCADADO_00425 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHCADADO_00426 3.6e-134 yvoA K transcriptional
KHCADADO_00427 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KHCADADO_00428 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
KHCADADO_00429 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
KHCADADO_00430 6.7e-99 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
KHCADADO_00431 2.1e-63 yvmB K helix_turn_helix multiple antibiotic resistance protein
KHCADADO_00432 1e-200 yvmA EGP Major facilitator Superfamily
KHCADADO_00433 1.2e-50 yvlD S Membrane
KHCADADO_00434 2.6e-26 pspB KT PspC domain
KHCADADO_00435 3.4e-168 yvlB S Putative adhesin
KHCADADO_00436 8e-49 yvlA
KHCADADO_00437 6.7e-34 yvkN
KHCADADO_00438 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHCADADO_00439 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KHCADADO_00440 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KHCADADO_00441 1.2e-30 csbA S protein conserved in bacteria
KHCADADO_00442 1.3e-140 yvkC 2.7.9.2 GT Phosphotransferase
KHCADADO_00443 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KHCADADO_00444 7e-101 yvkB K Transcriptional regulator
KHCADADO_00445 7.9e-228 yvkA EGP Major facilitator Superfamily
KHCADADO_00446 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHCADADO_00447 5.3e-56 swrA S Swarming motility protein
KHCADADO_00448 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KHCADADO_00449 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KHCADADO_00450 1.6e-123 ftsE D cell division ATP-binding protein FtsE
KHCADADO_00451 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
KHCADADO_00452 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KHCADADO_00453 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHCADADO_00454 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHCADADO_00455 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHCADADO_00456 2.8e-66
KHCADADO_00457 1.9e-08 fliT S bacterial-type flagellum organization
KHCADADO_00458 2.9e-69 fliS N flagellar protein FliS
KHCADADO_00459 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KHCADADO_00460 6.1e-57 flaG N flagellar protein FlaG
KHCADADO_00461 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KHCADADO_00462 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KHCADADO_00463 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KHCADADO_00464 9.3e-39 yviE
KHCADADO_00465 7.8e-132 flgL N Belongs to the bacterial flagellin family
KHCADADO_00466 1.2e-264 flgK N flagellar hook-associated protein
KHCADADO_00467 2.4e-78 flgN NOU FlgN protein
KHCADADO_00468 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
KHCADADO_00469 7e-74 yvyF S flagellar protein
KHCADADO_00470 2.7e-129 comFC S Phosphoribosyl transferase domain
KHCADADO_00471 5.7e-46 comFB S Late competence development protein ComFB
KHCADADO_00472 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KHCADADO_00473 7.3e-155 degV S protein conserved in bacteria
KHCADADO_00474 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KHCADADO_00475 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KHCADADO_00476 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KHCADADO_00477 6e-163 yvhJ K Transcriptional regulator
KHCADADO_00478 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KHCADADO_00479 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KHCADADO_00480 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
KHCADADO_00481 9.6e-104 tuaF M protein involved in exopolysaccharide biosynthesis
KHCADADO_00483 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
KHCADADO_00484 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHCADADO_00485 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KHCADADO_00486 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KHCADADO_00487 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KHCADADO_00488 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KHCADADO_00489 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KHCADADO_00490 6e-38
KHCADADO_00491 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KHCADADO_00492 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KHCADADO_00493 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KHCADADO_00494 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHCADADO_00495 1.2e-109 ggaA M Glycosyltransferase like family 2
KHCADADO_00496 8.8e-75 ggaA M Glycosyltransferase like family 2
KHCADADO_00497 1.3e-54 ggaA M Glycosyltransferase like family 2
KHCADADO_00499 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KHCADADO_00500 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KHCADADO_00501 1.1e-150 tagG GM Transport permease protein
KHCADADO_00502 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHCADADO_00503 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
KHCADADO_00504 1.2e-42 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KHCADADO_00505 1.1e-19 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KHCADADO_00506 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KHCADADO_00507 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KHCADADO_00508 1.2e-260
KHCADADO_00509 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KHCADADO_00510 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KHCADADO_00511 4.8e-38 gerBA EG Spore germination protein
KHCADADO_00512 8.3e-213 gerBA EG Spore germination protein
KHCADADO_00513 7.7e-27 gerBB E Spore germination protein
KHCADADO_00514 1.6e-137 gerBB E Spore germination protein
KHCADADO_00515 7.6e-216 gerAC S Spore germination protein
KHCADADO_00516 1.9e-248 ywtG EGP Major facilitator Superfamily
KHCADADO_00517 8.4e-171 ywtF K Transcriptional regulator
KHCADADO_00518 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KHCADADO_00519 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KHCADADO_00520 3.6e-21 ywtC
KHCADADO_00521 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KHCADADO_00522 8.6e-70 pgsC S biosynthesis protein
KHCADADO_00523 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KHCADADO_00524 1.9e-178 rbsR K transcriptional
KHCADADO_00525 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHCADADO_00526 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KHCADADO_00527 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KHCADADO_00528 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
KHCADADO_00529 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KHCADADO_00530 4.6e-94 batE T Sh3 type 3 domain protein
KHCADADO_00531 3.6e-48 ywsA S Protein of unknown function (DUF3892)
KHCADADO_00532 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
KHCADADO_00533 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KHCADADO_00534 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KHCADADO_00535 1.1e-169 alsR K LysR substrate binding domain
KHCADADO_00536 3.3e-239 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KHCADADO_00537 7.5e-126 ywrJ
KHCADADO_00538 5.8e-92 cotB
KHCADADO_00539 7.5e-24 cotB
KHCADADO_00540 1.2e-210 cotH M Spore Coat
KHCADADO_00541 3.6e-12
KHCADADO_00542 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KHCADADO_00543 2.9e-54 S Domain of unknown function (DUF4181)
KHCADADO_00544 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KHCADADO_00545 2.1e-82 ywrC K Transcriptional regulator
KHCADADO_00546 2.4e-104 ywrB P Chromate transporter
KHCADADO_00547 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
KHCADADO_00549 2.7e-102 ywqN S NAD(P)H-dependent
KHCADADO_00550 2.9e-162 K Transcriptional regulator
KHCADADO_00551 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KHCADADO_00552 1.7e-52 S MORN repeat variant
KHCADADO_00553 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
KHCADADO_00554 1.3e-38 ywqI S Family of unknown function (DUF5344)
KHCADADO_00555 3.3e-15 S Domain of unknown function (DUF5082)
KHCADADO_00556 3.4e-154 ywqG S Domain of unknown function (DUF1963)
KHCADADO_00557 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHCADADO_00558 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KHCADADO_00559 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KHCADADO_00560 2e-116 ywqC M biosynthesis protein
KHCADADO_00561 1.2e-17
KHCADADO_00562 3.8e-309 ywqB S SWIM zinc finger
KHCADADO_00563 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KHCADADO_00564 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KHCADADO_00565 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
KHCADADO_00566 9.8e-58 ssbB L Single-stranded DNA-binding protein
KHCADADO_00567 9.4e-32 ywpG
KHCADADO_00568 1.1e-66 ywpF S YwpF-like protein
KHCADADO_00569 8e-51 srtA 3.4.22.70 M Sortase family
KHCADADO_00570 1.4e-153 ywpD T Histidine kinase
KHCADADO_00571 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHCADADO_00572 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KHCADADO_00573 2.1e-199 S aspartate phosphatase
KHCADADO_00574 1.5e-141 flhP N flagellar basal body
KHCADADO_00575 6.9e-126 flhO N flagellar basal body
KHCADADO_00576 3.5e-180 mbl D Rod shape-determining protein
KHCADADO_00577 3e-44 spoIIID K Stage III sporulation protein D
KHCADADO_00578 2.1e-70 ywoH K COG1846 Transcriptional regulators
KHCADADO_00579 2.7e-211 ywoG EGP Major facilitator Superfamily
KHCADADO_00580 1.2e-231 ywoF P Right handed beta helix region
KHCADADO_00581 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KHCADADO_00582 4.4e-242 ywoD EGP Major facilitator superfamily
KHCADADO_00583 2.5e-58 phzA Q Isochorismatase family
KHCADADO_00584 1.2e-77
KHCADADO_00585 2.5e-225 amt P Ammonium transporter
KHCADADO_00586 1.6e-58 nrgB K Belongs to the P(II) protein family
KHCADADO_00587 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KHCADADO_00588 3.5e-73 ywnJ S VanZ like family
KHCADADO_00589 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KHCADADO_00590 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KHCADADO_00591 2.7e-14 ywnC S Family of unknown function (DUF5362)
KHCADADO_00592 2.2e-70 ywnF S Family of unknown function (DUF5392)
KHCADADO_00593 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHCADADO_00594 4.1e-144 mta K transcriptional
KHCADADO_00595 2.6e-59 ywnC S Family of unknown function (DUF5362)
KHCADADO_00596 1.6e-114 ywnB S NAD(P)H-binding
KHCADADO_00597 1.7e-64 ywnA K Transcriptional regulator
KHCADADO_00598 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KHCADADO_00599 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KHCADADO_00600 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KHCADADO_00602 3.8e-11 csbD K CsbD-like
KHCADADO_00603 3e-84 ywmF S Peptidase M50
KHCADADO_00604 1.3e-103 S response regulator aspartate phosphatase
KHCADADO_00605 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KHCADADO_00606 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KHCADADO_00608 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KHCADADO_00609 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KHCADADO_00610 2e-178 spoIID D Stage II sporulation protein D
KHCADADO_00611 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHCADADO_00612 1.6e-134 ywmB S TATA-box binding
KHCADADO_00613 1.3e-32 ywzB S membrane
KHCADADO_00614 4.3e-88 ywmA
KHCADADO_00615 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KHCADADO_00616 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHCADADO_00617 1.5e-127 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHCADADO_00618 2.8e-171 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHCADADO_00619 6.8e-84 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHCADADO_00620 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHCADADO_00621 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHCADADO_00622 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHCADADO_00623 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
KHCADADO_00624 2.5e-62 atpI S ATP synthase
KHCADADO_00625 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHCADADO_00626 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHCADADO_00627 7.2e-95 ywlG S Belongs to the UPF0340 family
KHCADADO_00628 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KHCADADO_00629 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHCADADO_00630 1.7e-91 mntP P Probably functions as a manganese efflux pump
KHCADADO_00631 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KHCADADO_00632 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KHCADADO_00633 6.1e-112 spoIIR S stage II sporulation protein R
KHCADADO_00634 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
KHCADADO_00636 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KHCADADO_00637 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHCADADO_00638 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHCADADO_00639 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KHCADADO_00640 8.6e-160 ywkB S Membrane transport protein
KHCADADO_00641 1.9e-264 sfcA 1.1.1.38 C malic enzyme
KHCADADO_00642 2.4e-104 tdk 2.7.1.21 F thymidine kinase
KHCADADO_00643 1.1e-32 rpmE J Binds the 23S rRNA
KHCADADO_00644 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KHCADADO_00645 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KHCADADO_00646 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHCADADO_00647 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHCADADO_00648 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KHCADADO_00649 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
KHCADADO_00650 2.4e-92 ywjG S Domain of unknown function (DUF2529)
KHCADADO_00651 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KHCADADO_00652 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KHCADADO_00653 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KHCADADO_00654 0.0 fadF C COG0247 Fe-S oxidoreductase
KHCADADO_00655 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KHCADADO_00656 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KHCADADO_00657 2.7e-42 ywjC
KHCADADO_00658 4.8e-96 ywjB H RibD C-terminal domain
KHCADADO_00659 0.0 ywjA V ABC transporter
KHCADADO_00660 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHCADADO_00661 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
KHCADADO_00662 2.4e-98 narJ 1.7.5.1 C nitrate reductase
KHCADADO_00663 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
KHCADADO_00664 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KHCADADO_00665 7e-86 arfM T cyclic nucleotide binding
KHCADADO_00666 4.3e-140 ywiC S YwiC-like protein
KHCADADO_00667 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
KHCADADO_00668 9.8e-214 narK P COG2223 Nitrate nitrite transporter
KHCADADO_00669 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KHCADADO_00670 4.7e-73 ywiB S protein conserved in bacteria
KHCADADO_00671 1e-07 S Bacteriocin subtilosin A
KHCADADO_00672 2.6e-271 C Fe-S oxidoreductases
KHCADADO_00674 3.3e-132 cbiO V ABC transporter
KHCADADO_00675 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KHCADADO_00676 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
KHCADADO_00677 1.2e-249 L Peptidase, M16
KHCADADO_00679 2.9e-249 ywhL CO amine dehydrogenase activity
KHCADADO_00680 2.5e-205 ywhK CO amine dehydrogenase activity
KHCADADO_00681 2.3e-79 S aspartate phosphatase
KHCADADO_00683 1e-84 ywhH S Aminoacyl-tRNA editing domain
KHCADADO_00684 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
KHCADADO_00685 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KHCADADO_00686 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KHCADADO_00687 5.2e-95 ywhD S YwhD family
KHCADADO_00688 5.1e-119 ywhC S Peptidase family M50
KHCADADO_00689 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KHCADADO_00690 3.3e-71 ywhA K Transcriptional regulator
KHCADADO_00691 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHCADADO_00693 2.6e-242 mmr U Major Facilitator Superfamily
KHCADADO_00694 2.8e-79 yffB K Transcriptional regulator
KHCADADO_00695 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
KHCADADO_00696 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
KHCADADO_00697 3.1e-36 ywzC S Belongs to the UPF0741 family
KHCADADO_00698 1.6e-111 rsfA_1
KHCADADO_00699 5.2e-159 ywfM EG EamA-like transporter family
KHCADADO_00700 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KHCADADO_00701 9.2e-164 cysL K Transcriptional regulator
KHCADADO_00702 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KHCADADO_00703 1.1e-146 ywfI C May function as heme-dependent peroxidase
KHCADADO_00704 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
KHCADADO_00705 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
KHCADADO_00706 2.9e-210 bacE EGP Major facilitator Superfamily
KHCADADO_00707 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KHCADADO_00708 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHCADADO_00709 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KHCADADO_00710 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KHCADADO_00711 4.6e-206 ywfA EGP Major facilitator Superfamily
KHCADADO_00712 4e-262 lysP E amino acid
KHCADADO_00713 2e-249 rocB E arginine degradation protein
KHCADADO_00714 2.6e-33 rocB E arginine degradation protein
KHCADADO_00715 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KHCADADO_00716 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KHCADADO_00717 1.8e-78
KHCADADO_00718 3.5e-87 spsL 5.1.3.13 M Spore Coat
KHCADADO_00719 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KHCADADO_00720 1.3e-19 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHCADADO_00721 2e-152 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHCADADO_00722 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHCADADO_00723 1.7e-190 spsG M Spore Coat
KHCADADO_00724 9.7e-132 spsF M Spore Coat
KHCADADO_00725 3.2e-214 spsE 2.5.1.56 M acid synthase
KHCADADO_00726 4e-164 spsD 2.3.1.210 K Spore Coat
KHCADADO_00727 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
KHCADADO_00728 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
KHCADADO_00729 2.8e-145 spsA M Spore Coat
KHCADADO_00730 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KHCADADO_00731 4.3e-59 ywdK S small membrane protein
KHCADADO_00732 1.3e-238 ywdJ F Xanthine uracil
KHCADADO_00733 7.7e-49 ywdI S Family of unknown function (DUF5327)
KHCADADO_00734 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KHCADADO_00735 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHCADADO_00736 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
KHCADADO_00738 1.4e-113 ywdD
KHCADADO_00739 1.3e-57 pex K Transcriptional regulator PadR-like family
KHCADADO_00740 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KHCADADO_00741 2e-28 ywdA
KHCADADO_00742 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
KHCADADO_00743 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHCADADO_00744 1e-139 focA P Formate/nitrite transporter
KHCADADO_00745 2.4e-150 sacT K transcriptional antiterminator
KHCADADO_00747 0.0 vpr O Belongs to the peptidase S8 family
KHCADADO_00748 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHCADADO_00749 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KHCADADO_00750 2.9e-202 rodA D Belongs to the SEDS family
KHCADADO_00751 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
KHCADADO_00752 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KHCADADO_00753 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KHCADADO_00754 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHCADADO_00755 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KHCADADO_00756 1e-35 ywzA S membrane
KHCADADO_00757 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KHCADADO_00758 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KHCADADO_00759 9.5e-60 gtcA S GtrA-like protein
KHCADADO_00760 2e-73 ywcC K transcriptional regulator
KHCADADO_00761 1.7e-32 ywcC K transcriptional regulator
KHCADADO_00763 9.8e-49 ywcB S Protein of unknown function, DUF485
KHCADADO_00764 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHCADADO_00765 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KHCADADO_00766 2.6e-225 ywbN P Dyp-type peroxidase family protein
KHCADADO_00767 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
KHCADADO_00768 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
KHCADADO_00769 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KHCADADO_00770 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KHCADADO_00771 4.3e-153 ywbI K Transcriptional regulator
KHCADADO_00772 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KHCADADO_00773 2.3e-111 ywbG M effector of murein hydrolase
KHCADADO_00774 1.9e-209 ywbF EGP Major facilitator Superfamily
KHCADADO_00775 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
KHCADADO_00776 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
KHCADADO_00777 4.4e-67 ywbC 4.4.1.5 E glyoxalase
KHCADADO_00778 1.8e-127 ywbB S Protein of unknown function (DUF2711)
KHCADADO_00779 4.3e-109 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHCADADO_00780 2.6e-121 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHCADADO_00781 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
KHCADADO_00782 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHCADADO_00783 4e-153 sacY K transcriptional antiterminator
KHCADADO_00784 7e-169 gspA M General stress
KHCADADO_00785 3.2e-112 ywaF S Integral membrane protein
KHCADADO_00786 8.1e-88 ywaE K Transcriptional regulator
KHCADADO_00787 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHCADADO_00788 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
KHCADADO_00789 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
KHCADADO_00790 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KHCADADO_00791 5e-14 S D-Ala-teichoic acid biosynthesis protein
KHCADADO_00792 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_00793 1.2e-232 dltB M membrane protein involved in D-alanine export
KHCADADO_00794 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_00795 5e-182 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHCADADO_00796 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_00797 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KHCADADO_00798 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KHCADADO_00799 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KHCADADO_00800 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHCADADO_00801 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KHCADADO_00802 1.1e-61 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KHCADADO_00803 4.4e-223 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KHCADADO_00804 1.1e-19 yxzF
KHCADADO_00805 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KHCADADO_00806 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KHCADADO_00807 1.4e-201 yxlH EGP Major facilitator Superfamily
KHCADADO_00808 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KHCADADO_00809 5.1e-167 yxlF V ABC transporter, ATP-binding protein
KHCADADO_00810 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
KHCADADO_00811 1.2e-31
KHCADADO_00812 3.9e-48 yxlC S Family of unknown function (DUF5345)
KHCADADO_00813 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
KHCADADO_00814 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KHCADADO_00815 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHCADADO_00816 0.0 cydD V ATP-binding protein
KHCADADO_00817 0.0 cydD V ATP-binding
KHCADADO_00818 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KHCADADO_00819 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
KHCADADO_00820 1.5e-229 cimH C COG3493 Na citrate symporter
KHCADADO_00821 0.0 3.4.24.84 O Peptidase family M48
KHCADADO_00823 3e-156 yxkH G Polysaccharide deacetylase
KHCADADO_00824 5.9e-205 msmK P Belongs to the ABC transporter superfamily
KHCADADO_00825 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
KHCADADO_00826 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KHCADADO_00827 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHCADADO_00828 4.1e-73 yxkC S Domain of unknown function (DUF4352)
KHCADADO_00829 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KHCADADO_00830 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
KHCADADO_00831 1.9e-166 yxjO K LysR substrate binding domain
KHCADADO_00832 2.4e-78 S Protein of unknown function (DUF1453)
KHCADADO_00833 1.5e-193 yxjM T Signal transduction histidine kinase
KHCADADO_00834 8.9e-116 K helix_turn_helix, Lux Regulon
KHCADADO_00835 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KHCADADO_00838 1e-87 yxjI S LURP-one-related
KHCADADO_00839 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
KHCADADO_00840 1e-220 yxjG 2.1.1.14 E Methionine synthase
KHCADADO_00841 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KHCADADO_00842 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KHCADADO_00843 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHCADADO_00844 1.2e-225 yxjC EG COG2610 H gluconate symporter and related permeases
KHCADADO_00845 3.2e-15 yxjC EG COG2610 H gluconate symporter and related permeases
KHCADADO_00846 3.1e-161 rlmA 2.1.1.187 Q Methyltransferase domain
KHCADADO_00847 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHCADADO_00848 1.2e-22 T Domain of unknown function (DUF4163)
KHCADADO_00849 2.7e-48 yxiS
KHCADADO_00850 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KHCADADO_00851 6.6e-224 citH C Citrate transporter
KHCADADO_00852 5e-144 exoK GH16 M licheninase activity
KHCADADO_00853 8.3e-151 licT K transcriptional antiterminator
KHCADADO_00854 6.6e-114
KHCADADO_00855 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
KHCADADO_00856 5.4e-50 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KHCADADO_00857 2.8e-89 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KHCADADO_00858 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
KHCADADO_00861 1.6e-48 yxiJ S YxiJ-like protein
KHCADADO_00862 1.2e-96 yxiI S Protein of unknown function (DUF2716)
KHCADADO_00863 3.8e-81
KHCADADO_00864 4.9e-46
KHCADADO_00865 3.7e-75 yxiG
KHCADADO_00866 6.4e-63
KHCADADO_00867 1.7e-84
KHCADADO_00868 1.5e-71 yxxG
KHCADADO_00869 0.0 wapA M COG3209 Rhs family protein
KHCADADO_00870 0.0 wapA M COG3209 Rhs family protein
KHCADADO_00871 2.9e-168 yxxF EG EamA-like transporter family
KHCADADO_00872 1.1e-72 yxiE T Belongs to the universal stress protein A family
KHCADADO_00873 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHCADADO_00874 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHCADADO_00875 3.6e-51
KHCADADO_00876 0.0 S nuclease activity
KHCADADO_00877 3.6e-39 yxiC S Family of unknown function (DUF5344)
KHCADADO_00878 2.1e-21 S Domain of unknown function (DUF5082)
KHCADADO_00879 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KHCADADO_00880 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KHCADADO_00881 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
KHCADADO_00882 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KHCADADO_00883 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
KHCADADO_00884 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KHCADADO_00885 6.1e-252 lysP E amino acid
KHCADADO_00886 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KHCADADO_00887 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KHCADADO_00888 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHCADADO_00889 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KHCADADO_00890 2e-112 yxxB S Domain of Unknown Function (DUF1206)
KHCADADO_00891 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
KHCADADO_00892 2e-255 yxeQ S MmgE/PrpD family
KHCADADO_00893 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
KHCADADO_00894 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
KHCADADO_00895 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
KHCADADO_00896 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
KHCADADO_00897 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHCADADO_00898 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHCADADO_00900 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KHCADADO_00901 6.2e-151 yidA S hydrolases of the HAD superfamily
KHCADADO_00904 1.3e-20 yxeE
KHCADADO_00905 1.9e-16 yxeD
KHCADADO_00906 8.5e-69
KHCADADO_00907 6e-177 fhuD P ABC transporter
KHCADADO_00908 1.5e-58 yxeA S Protein of unknown function (DUF1093)
KHCADADO_00909 0.0 yxdM V ABC transporter (permease)
KHCADADO_00910 9.4e-141 yxdL V ABC transporter, ATP-binding protein
KHCADADO_00911 1.3e-182 T PhoQ Sensor
KHCADADO_00912 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_00913 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KHCADADO_00914 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KHCADADO_00915 2.3e-167 iolH G Xylose isomerase-like TIM barrel
KHCADADO_00916 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KHCADADO_00917 1.3e-235 iolF EGP Major facilitator Superfamily
KHCADADO_00918 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KHCADADO_00919 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KHCADADO_00920 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KHCADADO_00921 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KHCADADO_00922 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KHCADADO_00923 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
KHCADADO_00924 3.7e-176 iolS C Aldo keto reductase
KHCADADO_00926 8.3e-48 yxcD S Protein of unknown function (DUF2653)
KHCADADO_00927 2.3e-246 csbC EGP Major facilitator Superfamily
KHCADADO_00928 0.0 htpG O Molecular chaperone. Has ATPase activity
KHCADADO_00930 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
KHCADADO_00931 3.4e-13 yxbF K Bacterial regulatory proteins, tetR family
KHCADADO_00932 4.5e-183 yxbF K Bacterial regulatory proteins, tetR family
KHCADADO_00933 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KHCADADO_00934 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
KHCADADO_00935 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
KHCADADO_00936 3.3e-127 yxbB Q Met-10+ like-protein
KHCADADO_00937 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
KHCADADO_00938 1.1e-86 yxnB
KHCADADO_00939 0.0 asnB 6.3.5.4 E Asparagine synthase
KHCADADO_00940 7.6e-214 yxaM U MFS_1 like family
KHCADADO_00941 6.8e-93 S PQQ-like domain
KHCADADO_00942 3.5e-65 S Family of unknown function (DUF5391)
KHCADADO_00943 1.1e-75 yxaI S membrane protein domain
KHCADADO_00944 1.4e-228 P Protein of unknown function (DUF418)
KHCADADO_00945 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
KHCADADO_00946 7.1e-101 yxaF K Transcriptional regulator
KHCADADO_00947 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_00948 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
KHCADADO_00949 5.2e-50 S LrgA family
KHCADADO_00950 2.6e-118 yxaC M effector of murein hydrolase
KHCADADO_00951 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
KHCADADO_00952 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KHCADADO_00953 7.3e-127 gntR K transcriptional
KHCADADO_00954 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KHCADADO_00955 6.5e-121 gntP EG COG2610 H gluconate symporter and related permeases
KHCADADO_00956 1.6e-83 gntP EG COG2610 H gluconate symporter and related permeases
KHCADADO_00957 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHCADADO_00958 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KHCADADO_00959 3.8e-287 ahpF O Alkyl hydroperoxide reductase
KHCADADO_00960 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHCADADO_00961 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
KHCADADO_00962 1.3e-128 yydK K Transcriptional regulator
KHCADADO_00963 7.6e-13
KHCADADO_00964 3.3e-119 S ABC-2 family transporter protein
KHCADADO_00965 1.8e-110 prrC P ABC transporter
KHCADADO_00966 8.4e-134 yydH O Peptidase M50
KHCADADO_00967 7.7e-185 S Radical SAM superfamily
KHCADADO_00968 8e-12
KHCADADO_00969 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KHCADADO_00970 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
KHCADADO_00971 3.5e-65
KHCADADO_00972 7.3e-280 S Calcineurin-like phosphoesterase
KHCADADO_00973 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHCADADO_00974 1.1e-09 S YyzF-like protein
KHCADADO_00975 4.2e-71
KHCADADO_00976 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KHCADADO_00978 2.1e-33 yycQ S Protein of unknown function (DUF2651)
KHCADADO_00979 2.6e-58 yycP
KHCADADO_00980 3e-140 yycP
KHCADADO_00981 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KHCADADO_00982 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
KHCADADO_00983 5e-188 S aspartate phosphatase
KHCADADO_00985 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KHCADADO_00986 9.7e-261 rocE E amino acid
KHCADADO_00987 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KHCADADO_00988 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KHCADADO_00989 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHCADADO_00990 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KHCADADO_00991 7.3e-155 yycI S protein conserved in bacteria
KHCADADO_00992 3.6e-260 yycH S protein conserved in bacteria
KHCADADO_00993 0.0 vicK 2.7.13.3 T Histidine kinase
KHCADADO_00994 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_00999 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHCADADO_01000 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHCADADO_01001 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KHCADADO_01002 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KHCADADO_01004 1.9e-15 yycC K YycC-like protein
KHCADADO_01005 8.4e-221 yeaN P COG2807 Cyanate permease
KHCADADO_01006 1.8e-20 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHCADADO_01007 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHCADADO_01008 2.2e-73 rplI J binds to the 23S rRNA
KHCADADO_01009 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KHCADADO_01010 2.9e-160 yybS S membrane
KHCADADO_01012 3.9e-84 cotF M Spore coat protein
KHCADADO_01013 1.4e-68 ydeP3 K Transcriptional regulator
KHCADADO_01014 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KHCADADO_01015 1.3e-70
KHCADADO_01017 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
KHCADADO_01018 1e-16
KHCADADO_01019 1.3e-78 yybN S Protein of unknown function (DUF2712)
KHCADADO_01020 4.1e-125
KHCADADO_01021 9e-122
KHCADADO_01022 2e-127 S Protein of unknown function (DUF2705)
KHCADADO_01023 9.5e-92 V ATPases associated with a variety of cellular activities
KHCADADO_01024 6.2e-132
KHCADADO_01025 5.9e-67 yybH S SnoaL-like domain
KHCADADO_01026 3e-124 yybG S Pentapeptide repeat-containing protein
KHCADADO_01027 3.2e-220 ynfM EGP Major facilitator Superfamily
KHCADADO_01028 2.1e-165 yybE K Transcriptional regulator
KHCADADO_01029 2e-79 yjcF S Acetyltransferase (GNAT) domain
KHCADADO_01030 2.7e-77 yybC
KHCADADO_01031 3e-127 S Metallo-beta-lactamase superfamily
KHCADADO_01032 5.6e-77 yybA 2.3.1.57 K transcriptional
KHCADADO_01033 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
KHCADADO_01034 1.5e-101 yyaS S Membrane
KHCADADO_01035 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
KHCADADO_01036 5.4e-67 yyaQ S YjbR
KHCADADO_01037 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
KHCADADO_01038 1.7e-249 tetL EGP Major facilitator Superfamily
KHCADADO_01039 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
KHCADADO_01040 5.1e-61 yyaN K MerR HTH family regulatory protein
KHCADADO_01041 3.3e-161 yyaM EG EamA-like transporter family
KHCADADO_01042 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KHCADADO_01043 9.5e-169 yyaK S CAAX protease self-immunity
KHCADADO_01044 3.8e-246 EGP Major facilitator superfamily
KHCADADO_01045 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
KHCADADO_01046 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHCADADO_01047 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KHCADADO_01048 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
KHCADADO_01049 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHCADADO_01050 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KHCADADO_01051 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
KHCADADO_01052 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KHCADADO_01053 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KHCADADO_01054 2.3e-33 yyzM S protein conserved in bacteria
KHCADADO_01055 8.1e-177 yyaD S Membrane
KHCADADO_01056 1.6e-111 yyaC S Sporulation protein YyaC
KHCADADO_01057 2.1e-149 spo0J K Belongs to the ParB family
KHCADADO_01058 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
KHCADADO_01059 1.5e-74 S Bacterial PH domain
KHCADADO_01060 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KHCADADO_01061 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KHCADADO_01062 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KHCADADO_01063 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHCADADO_01064 6.5e-108 jag S single-stranded nucleic acid binding R3H
KHCADADO_01065 2.6e-111 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHCADADO_01066 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KHCADADO_01067 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHCADADO_01068 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KHCADADO_01069 2.4e-33 yaaA S S4 domain
KHCADADO_01070 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHCADADO_01071 1.8e-37 yaaB S Domain of unknown function (DUF370)
KHCADADO_01072 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHCADADO_01073 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHCADADO_01074 1.1e-130 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_01075 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_01076 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KHCADADO_01077 2.8e-64 yngL S Protein of unknown function (DUF1360)
KHCADADO_01078 1.3e-306 yngK T Glycosyl hydrolase-like 10
KHCADADO_01080 1.8e-31 S Family of unknown function (DUF5367)
KHCADADO_01081 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KHCADADO_01082 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KHCADADO_01083 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KHCADADO_01084 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KHCADADO_01085 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KHCADADO_01086 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KHCADADO_01087 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KHCADADO_01088 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
KHCADADO_01089 5.5e-104 yngC S membrane-associated protein
KHCADADO_01090 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KHCADADO_01091 2.4e-80 yngA S membrane
KHCADADO_01092 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KHCADADO_01093 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
KHCADADO_01095 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KHCADADO_01096 8.2e-252 agcS E Sodium alanine symporter
KHCADADO_01097 1.3e-57 ynfC
KHCADADO_01098 2.3e-12
KHCADADO_01099 5.2e-181 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHCADADO_01100 4.3e-225 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHCADADO_01101 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHCADADO_01102 6.6e-69 yccU S CoA-binding protein
KHCADADO_01103 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHCADADO_01104 4.1e-49 yneR S Belongs to the HesB IscA family
KHCADADO_01105 1.3e-53 yneQ
KHCADADO_01106 1.2e-73 yneP S Thioesterase-like superfamily
KHCADADO_01107 3.9e-35 tlp S Belongs to the Tlp family
KHCADADO_01108 3.1e-08 sspN S Small acid-soluble spore protein N family
KHCADADO_01110 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KHCADADO_01111 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KHCADADO_01112 2.2e-14 sspO S Belongs to the SspO family
KHCADADO_01113 3.9e-19 sspP S Belongs to the SspP family
KHCADADO_01114 4.1e-65 hspX O Spore coat protein
KHCADADO_01115 4.2e-74 yneK S Protein of unknown function (DUF2621)
KHCADADO_01116 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KHCADADO_01117 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KHCADADO_01118 7.1e-127 ccdA O cytochrome c biogenesis protein
KHCADADO_01119 1.8e-28 yneF S UPF0154 protein
KHCADADO_01120 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
KHCADADO_01121 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KHCADADO_01122 1.3e-32 ynzC S UPF0291 protein
KHCADADO_01123 9.2e-113 yneB L resolvase
KHCADADO_01124 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KHCADADO_01125 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHCADADO_01127 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KHCADADO_01128 1.5e-92 yndM S Protein of unknown function (DUF2512)
KHCADADO_01129 8.6e-139 yndL S Replication protein
KHCADADO_01131 0.0 yndJ S YndJ-like protein
KHCADADO_01132 2.6e-117 yndH S Domain of unknown function (DUF4166)
KHCADADO_01133 7.7e-154 yndG S DoxX-like family
KHCADADO_01134 1.2e-183 gerLC S Spore germination protein
KHCADADO_01135 4.5e-197 gerAB U Spore germination
KHCADADO_01136 5.7e-286 gerAA EG Spore germination protein
KHCADADO_01139 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
KHCADADO_01140 1.8e-71
KHCADADO_01141 7.9e-25 tatA U protein secretion
KHCADADO_01144 1.3e-134 S Domain of unknown function, YrpD
KHCADADO_01146 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHCADADO_01149 5.2e-15
KHCADADO_01150 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KHCADADO_01151 6.3e-84 yncE S Protein of unknown function (DUF2691)
KHCADADO_01152 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHCADADO_01153 3.5e-247 iolT EGP Major facilitator Superfamily
KHCADADO_01154 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
KHCADADO_01155 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
KHCADADO_01156 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KHCADADO_01157 1e-215 xylR GK ROK family
KHCADADO_01158 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
KHCADADO_01159 2.7e-255 xynT G MFS/sugar transport protein
KHCADADO_01160 9e-43 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
KHCADADO_01161 5.7e-27 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
KHCADADO_01164 6.4e-60 ynaF
KHCADADO_01165 1.9e-123 ynaE S Domain of unknown function (DUF3885)
KHCADADO_01166 2e-99 ynaD J Acetyltransferase (GNAT) domain
KHCADADO_01167 4.9e-145 ynaC
KHCADADO_01168 6.8e-80 G regulation of fungal-type cell wall biogenesis
KHCADADO_01169 5.8e-39
KHCADADO_01170 2.5e-32
KHCADADO_01171 5e-10
KHCADADO_01172 7e-261 glnA 6.3.1.2 E glutamine synthetase
KHCADADO_01173 1.1e-68 glnR K transcriptional
KHCADADO_01174 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KHCADADO_01175 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHCADADO_01176 1.7e-176 spoVK O stage V sporulation protein K
KHCADADO_01177 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KHCADADO_01178 2e-109 ymaB
KHCADADO_01179 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHCADADO_01180 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHCADADO_01181 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KHCADADO_01182 6.5e-22 ymzA
KHCADADO_01183 6.3e-23
KHCADADO_01184 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KHCADADO_01185 1.1e-167 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHCADADO_01186 2.1e-46 ymaF S YmaF family
KHCADADO_01188 4.9e-51 ebrA P Small Multidrug Resistance protein
KHCADADO_01189 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
KHCADADO_01190 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
KHCADADO_01191 2.1e-126 ymaC S Replication protein
KHCADADO_01192 6.4e-24 aprX O Belongs to the peptidase S8 family
KHCADADO_01193 2.2e-218 aprX O Belongs to the peptidase S8 family
KHCADADO_01194 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
KHCADADO_01195 1.2e-61 ymzB
KHCADADO_01196 2.5e-233 cypA C Cytochrome P450
KHCADADO_01197 0.0 pks13 HQ Beta-ketoacyl synthase
KHCADADO_01198 5.8e-149 pks13 HQ Beta-ketoacyl synthase
KHCADADO_01199 0.0 dhbF IQ polyketide synthase
KHCADADO_01200 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
KHCADADO_01201 0.0 pfaA Q Polyketide synthase of type I
KHCADADO_01202 0.0 rhiB IQ polyketide synthase
KHCADADO_01203 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KHCADADO_01204 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
KHCADADO_01205 1.3e-245 pksG 2.3.3.10 I synthase
KHCADADO_01206 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KHCADADO_01207 1.4e-37 acpK IQ Phosphopantetheine attachment site
KHCADADO_01208 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KHCADADO_01209 2.4e-186 pksD Q Acyl transferase domain
KHCADADO_01211 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KHCADADO_01212 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
KHCADADO_01213 4.4e-109 pksA K Transcriptional regulator
KHCADADO_01214 1.2e-97 ymcC S Membrane
KHCADADO_01216 2.3e-70 S Regulatory protein YrvL
KHCADADO_01217 3e-133 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHCADADO_01218 9.6e-198 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHCADADO_01219 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHCADADO_01220 2.2e-88 cotE S Spore coat protein
KHCADADO_01221 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KHCADADO_01222 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHCADADO_01223 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KHCADADO_01224 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KHCADADO_01225 1.2e-36 spoVS S Stage V sporulation protein S
KHCADADO_01226 1.4e-68 ymdB S protein conserved in bacteria
KHCADADO_01227 5.7e-73 ymdB S protein conserved in bacteria
KHCADADO_01228 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
KHCADADO_01229 1e-215 pbpX V Beta-lactamase
KHCADADO_01230 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHCADADO_01231 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
KHCADADO_01232 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHCADADO_01233 3.5e-27 ymfM S protein conserved in bacteria
KHCADADO_01234 1.7e-70 ymfM S protein conserved in bacteria
KHCADADO_01235 1.8e-142 ymfK S Protein of unknown function (DUF3388)
KHCADADO_01236 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
KHCADADO_01237 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KHCADADO_01238 1.4e-242 ymfH S zinc protease
KHCADADO_01239 2.6e-236 ymfF S Peptidase M16
KHCADADO_01240 1.5e-206 ymfD EGP Major facilitator Superfamily
KHCADADO_01241 1.4e-133 ymfC K Transcriptional regulator
KHCADADO_01242 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KHCADADO_01243 4.4e-32 S YlzJ-like protein
KHCADADO_01244 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KHCADADO_01245 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHCADADO_01246 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHCADADO_01247 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KHCADADO_01248 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHCADADO_01249 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KHCADADO_01250 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KHCADADO_01251 2.6e-42 ymxH S YlmC YmxH family
KHCADADO_01252 4.4e-233 pepR S Belongs to the peptidase M16 family
KHCADADO_01253 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KHCADADO_01254 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KHCADADO_01255 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHCADADO_01256 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KHCADADO_01257 6.9e-147 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHCADADO_01258 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHCADADO_01259 3e-44 ylxP S protein conserved in bacteria
KHCADADO_01260 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHCADADO_01261 2.2e-41 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHCADADO_01262 3.1e-47 ylxQ J ribosomal protein
KHCADADO_01263 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
KHCADADO_01264 1.1e-203 nusA K Participates in both transcription termination and antitermination
KHCADADO_01265 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
KHCADADO_01266 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHCADADO_01267 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KHCADADO_01268 7.7e-233 rasP M zinc metalloprotease
KHCADADO_01269 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KHCADADO_01270 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
KHCADADO_01271 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHCADADO_01272 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KHCADADO_01273 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KHCADADO_01274 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHCADADO_01275 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
KHCADADO_01276 4.3e-78 ylxL
KHCADADO_01277 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHCADADO_01278 3.9e-30 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KHCADADO_01279 7.5e-41 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KHCADADO_01280 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KHCADADO_01281 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
KHCADADO_01282 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KHCADADO_01283 2.6e-34 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KHCADADO_01284 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KHCADADO_01285 7.5e-158 flhG D Belongs to the ParA family
KHCADADO_01286 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
KHCADADO_01287 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHCADADO_01288 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHCADADO_01289 3.6e-132 fliR N Flagellar biosynthetic protein FliR
KHCADADO_01290 8.3e-22 fliQ N Role in flagellar biosynthesis
KHCADADO_01291 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
KHCADADO_01292 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
KHCADADO_01293 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KHCADADO_01294 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHCADADO_01295 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KHCADADO_01296 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
KHCADADO_01297 8.2e-140 flgG N Flagellar basal body rod
KHCADADO_01298 1.7e-72 flgD N Flagellar basal body rod modification protein
KHCADADO_01299 1.2e-221 fliK N Flagellar hook-length control protein
KHCADADO_01300 7.7e-37 ylxF S MgtE intracellular N domain
KHCADADO_01301 1.5e-69 fliJ N Flagellar biosynthesis chaperone
KHCADADO_01302 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KHCADADO_01303 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KHCADADO_01304 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KHCADADO_01305 5.9e-218 fliF N The M ring may be actively involved in energy transduction
KHCADADO_01306 7.2e-29 fliF N The M ring may be actively involved in energy transduction
KHCADADO_01307 1.9e-31 fliE N Flagellar hook-basal body
KHCADADO_01308 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
KHCADADO_01309 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KHCADADO_01310 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KHCADADO_01311 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KHCADADO_01312 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KHCADADO_01313 2.5e-169 xerC L tyrosine recombinase XerC
KHCADADO_01314 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KHCADADO_01315 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHCADADO_01316 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KHCADADO_01317 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KHCADADO_01318 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KHCADADO_01319 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KHCADADO_01320 7.3e-221 ylqG
KHCADADO_01321 2.5e-38 ylqG
KHCADADO_01322 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHCADADO_01323 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHCADADO_01324 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KHCADADO_01325 5.3e-74 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KHCADADO_01326 1.2e-49 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KHCADADO_01327 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHCADADO_01328 1.3e-61 ylqD S YlqD protein
KHCADADO_01329 1.2e-36 ylqC S Belongs to the UPF0109 family
KHCADADO_01330 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KHCADADO_01331 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHCADADO_01332 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHCADADO_01333 2.9e-87
KHCADADO_01334 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KHCADADO_01335 0.0 smc D Required for chromosome condensation and partitioning
KHCADADO_01336 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KHCADADO_01337 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHCADADO_01338 6.1e-129 IQ reductase
KHCADADO_01339 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KHCADADO_01340 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KHCADADO_01341 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KHCADADO_01342 8.4e-78 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHCADADO_01343 6.3e-304 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHCADADO_01344 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
KHCADADO_01345 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
KHCADADO_01346 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
KHCADADO_01347 5.5e-59 asp S protein conserved in bacteria
KHCADADO_01348 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KHCADADO_01349 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
KHCADADO_01350 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KHCADADO_01351 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KHCADADO_01352 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KHCADADO_01353 2.4e-141 stp 3.1.3.16 T phosphatase
KHCADADO_01354 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KHCADADO_01355 6.7e-207 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHCADADO_01356 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHCADADO_01357 1.3e-66 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHCADADO_01358 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHCADADO_01359 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHCADADO_01360 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KHCADADO_01361 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KHCADADO_01362 1.5e-40 ylzA S Belongs to the UPF0296 family
KHCADADO_01363 2.4e-156 yloC S stress-induced protein
KHCADADO_01364 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KHCADADO_01365 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KHCADADO_01366 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KHCADADO_01367 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KHCADADO_01368 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KHCADADO_01369 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KHCADADO_01370 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KHCADADO_01371 1.1e-179 cysP P phosphate transporter
KHCADADO_01372 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KHCADADO_01374 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHCADADO_01375 2.1e-52 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KHCADADO_01376 2.3e-55 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KHCADADO_01377 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHCADADO_01378 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KHCADADO_01379 0.0 carB 6.3.5.5 F Belongs to the CarB family
KHCADADO_01380 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KHCADADO_01381 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHCADADO_01382 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KHCADADO_01383 9e-232 pyrP F Xanthine uracil
KHCADADO_01384 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHCADADO_01385 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHCADADO_01386 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHCADADO_01387 1.3e-63 dksA T COG1734 DnaK suppressor protein
KHCADADO_01388 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHCADADO_01389 2.6e-67 divIVA D Cell division initiation protein
KHCADADO_01390 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KHCADADO_01391 1.3e-39 yggT S membrane
KHCADADO_01392 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KHCADADO_01393 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHCADADO_01394 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KHCADADO_01395 2.4e-37 ylmC S sporulation protein
KHCADADO_01396 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
KHCADADO_01397 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KHCADADO_01398 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHCADADO_01399 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHCADADO_01400 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KHCADADO_01401 0.0 bpr O COG1404 Subtilisin-like serine proteases
KHCADADO_01402 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHCADADO_01403 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KHCADADO_01404 1e-54 sbp S small basic protein
KHCADADO_01405 2.8e-117 ylxX S protein conserved in bacteria
KHCADADO_01406 2.4e-103 ylxW S protein conserved in bacteria
KHCADADO_01407 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KHCADADO_01408 5.3e-167 murB 1.3.1.98 M cell wall formation
KHCADADO_01409 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHCADADO_01410 5.7e-186 spoVE D Belongs to the SEDS family
KHCADADO_01411 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHCADADO_01412 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHCADADO_01413 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHCADADO_01414 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KHCADADO_01415 1.3e-262 ftsI 3.4.16.4 M Penicillin-binding Protein
KHCADADO_01416 4.7e-118 ftsI 3.4.16.4 M Penicillin-binding Protein
KHCADADO_01417 3.7e-44 ftsL D Essential cell division protein
KHCADADO_01418 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KHCADADO_01419 2.9e-78 mraZ K Belongs to the MraZ family
KHCADADO_01420 1.2e-191 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KHCADADO_01421 3.3e-81 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KHCADADO_01422 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHCADADO_01423 4e-89 ylbP K n-acetyltransferase
KHCADADO_01424 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KHCADADO_01425 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KHCADADO_01426 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
KHCADADO_01428 2.8e-235 ylbM S Belongs to the UPF0348 family
KHCADADO_01429 6.8e-187 ylbL T Belongs to the peptidase S16 family
KHCADADO_01430 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
KHCADADO_01431 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
KHCADADO_01432 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHCADADO_01433 1.2e-79 rsmD 2.1.1.171 L Methyltransferase
KHCADADO_01434 7.5e-39 ylbG S UPF0298 protein
KHCADADO_01435 1.8e-75 ylbF S Belongs to the UPF0342 family
KHCADADO_01436 6.7e-37 ylbE S YlbE-like protein
KHCADADO_01437 4.1e-63 ylbD S Putative coat protein
KHCADADO_01438 3e-201 ylbC S protein with SCP PR1 domains
KHCADADO_01439 2.6e-74 ylbB T COG0517 FOG CBS domain
KHCADADO_01440 7e-62 ylbA S YugN-like family
KHCADADO_01441 3e-167 ctaG S cytochrome c oxidase
KHCADADO_01442 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KHCADADO_01443 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KHCADADO_01444 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHCADADO_01445 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KHCADADO_01446 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KHCADADO_01447 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KHCADADO_01448 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KHCADADO_01449 5.4e-212 ftsW D Belongs to the SEDS family
KHCADADO_01450 8.7e-44 ylaN S Belongs to the UPF0358 family
KHCADADO_01451 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
KHCADADO_01452 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KHCADADO_01453 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KHCADADO_01454 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KHCADADO_01455 2.5e-32 ylaI S protein conserved in bacteria
KHCADADO_01456 4.2e-47 ylaH S YlaH-like protein
KHCADADO_01457 0.0 typA T GTP-binding protein TypA
KHCADADO_01458 8.2e-22 S Family of unknown function (DUF5325)
KHCADADO_01459 1.8e-38 ylaE
KHCADADO_01460 1.2e-11 sigC S Putative zinc-finger
KHCADADO_01461 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
KHCADADO_01462 2.7e-42 ylaB
KHCADADO_01463 0.0 ylaA
KHCADADO_01464 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KHCADADO_01465 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KHCADADO_01466 6.9e-78 ykzC S Acetyltransferase (GNAT) family
KHCADADO_01467 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
KHCADADO_01468 7.1e-26 ykzI
KHCADADO_01469 7.1e-118 yktB S Belongs to the UPF0637 family
KHCADADO_01470 1.6e-42 yktA S Belongs to the UPF0223 family
KHCADADO_01471 3.5e-277 speA 4.1.1.19 E Arginine
KHCADADO_01472 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KHCADADO_01473 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KHCADADO_01474 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KHCADADO_01475 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KHCADADO_01476 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KHCADADO_01477 2e-115 recN L Putative cell-wall binding lipoprotein
KHCADADO_01479 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHCADADO_01480 1.4e-147 ykrA S hydrolases of the HAD superfamily
KHCADADO_01481 8.2e-31 ykzG S Belongs to the UPF0356 family
KHCADADO_01482 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHCADADO_01483 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KHCADADO_01484 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
KHCADADO_01485 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KHCADADO_01486 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KHCADADO_01487 1.5e-43 abrB K of stationary sporulation gene expression
KHCADADO_01488 7.7e-183 mreB D Rod-share determining protein MreBH
KHCADADO_01489 1.1e-12 S Uncharacterized protein YkpC
KHCADADO_01490 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KHCADADO_01491 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KHCADADO_01492 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KHCADADO_01493 8.1e-39 ykoA
KHCADADO_01494 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KHCADADO_01495 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KHCADADO_01496 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KHCADADO_01497 3.1e-136 fruR K Transcriptional regulator
KHCADADO_01498 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
KHCADADO_01499 7.9e-61 macB V ABC transporter, ATP-binding protein
KHCADADO_01500 5.6e-51 macB V ABC transporter, ATP-binding protein
KHCADADO_01501 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHCADADO_01502 1e-117 yknW S Yip1 domain
KHCADADO_01503 1.1e-195 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
KHCADADO_01504 1.2e-103 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
KHCADADO_01505 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
KHCADADO_01506 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KHCADADO_01507 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KHCADADO_01508 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KHCADADO_01509 8.1e-246 moeA 2.10.1.1 H molybdopterin
KHCADADO_01510 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KHCADADO_01511 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KHCADADO_01512 2.9e-147 yknT
KHCADADO_01513 1.9e-64 rok K Repressor of ComK
KHCADADO_01514 3.5e-22 rok K Repressor of ComK
KHCADADO_01515 4.4e-82 ykuV CO thiol-disulfide
KHCADADO_01516 3.9e-101 ykuU O Alkyl hydroperoxide reductase
KHCADADO_01517 8.8e-142 ykuT M Mechanosensitive ion channel
KHCADADO_01518 9e-37 ykuS S Belongs to the UPF0180 family
KHCADADO_01519 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KHCADADO_01520 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KHCADADO_01521 3.2e-80 fld C Flavodoxin
KHCADADO_01522 3.2e-177 ykuO
KHCADADO_01523 5.7e-88 fld C Flavodoxin domain
KHCADADO_01524 3.5e-168 ccpC K Transcriptional regulator
KHCADADO_01525 1.6e-76 ykuL S CBS domain
KHCADADO_01526 3.9e-27 ykzF S Antirepressor AbbA
KHCADADO_01527 4.4e-94 ykuK S Ribonuclease H-like
KHCADADO_01528 3.9e-37 ykuJ S protein conserved in bacteria
KHCADADO_01529 5.2e-234 ykuI T Diguanylate phosphodiesterase
KHCADADO_01531 1.7e-93 M Peptidoglycan-binding domain 1 protein
KHCADADO_01532 6.4e-273 3.2.1.132 M Putative peptidoglycan binding domain
KHCADADO_01533 3.4e-37 3.2.1.132 M Putative peptidoglycan binding domain
KHCADADO_01534 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHCADADO_01535 9.4e-166 ykuE S Metallophosphoesterase
KHCADADO_01536 4.6e-88 ykuD S protein conserved in bacteria
KHCADADO_01537 3.9e-12 ykuC EGP Major facilitator Superfamily
KHCADADO_01538 2.8e-210 ykuC EGP Major facilitator Superfamily
KHCADADO_01539 1.7e-84 ykyB S YkyB-like protein
KHCADADO_01540 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
KHCADADO_01541 2.2e-15
KHCADADO_01542 8e-224 patA 2.6.1.1 E Aminotransferase
KHCADADO_01543 0.0 pilS 2.7.13.3 T Histidine kinase
KHCADADO_01544 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KHCADADO_01545 8e-124 ykwD J protein with SCP PR1 domains
KHCADADO_01546 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KHCADADO_01547 2e-264 mcpC NT chemotaxis protein
KHCADADO_01548 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHCADADO_01549 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
KHCADADO_01550 7.2e-39 splA S Transcriptional regulator
KHCADADO_01551 4.2e-267 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHCADADO_01552 2.8e-30 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHCADADO_01553 2.1e-39 ptsH G phosphocarrier protein HPr
KHCADADO_01554 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHCADADO_01555 4.5e-128 glcT K antiterminator
KHCADADO_01557 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
KHCADADO_01559 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KHCADADO_01560 3.8e-09
KHCADADO_01561 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KHCADADO_01562 4.9e-90 stoA CO thiol-disulfide
KHCADADO_01563 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KHCADADO_01564 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
KHCADADO_01565 2.8e-28
KHCADADO_01566 6e-25 ykvS S protein conserved in bacteria
KHCADADO_01567 5.6e-46 ykvR S Protein of unknown function (DUF3219)
KHCADADO_01568 8.5e-133 G Glycosyl hydrolases family 18
KHCADADO_01569 1.2e-35 3.5.1.104 M LysM domain
KHCADADO_01570 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
KHCADADO_01571 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
KHCADADO_01572 2e-61 ykvN K Transcriptional regulator
KHCADADO_01573 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KHCADADO_01574 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KHCADADO_01575 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KHCADADO_01576 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KHCADADO_01577 8.7e-182 ykvI S membrane
KHCADADO_01578 1.9e-33 clpE O Belongs to the ClpA ClpB family
KHCADADO_01579 0.0 clpE O Belongs to the ClpA ClpB family
KHCADADO_01580 2.7e-138 motA N flagellar motor
KHCADADO_01581 2.5e-125 motB N Flagellar motor protein
KHCADADO_01582 1.3e-75 ykvE K transcriptional
KHCADADO_01583 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KHCADADO_01584 1.4e-64 eag
KHCADADO_01585 6.4e-09 S Spo0E like sporulation regulatory protein
KHCADADO_01586 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
KHCADADO_01587 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KHCADADO_01588 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KHCADADO_01589 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KHCADADO_01590 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KHCADADO_01591 8e-232 mtnE 2.6.1.83 E Aminotransferase
KHCADADO_01592 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KHCADADO_01593 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KHCADADO_01594 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KHCADADO_01596 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHCADADO_01597 0.0 kinE 2.7.13.3 T Histidine kinase
KHCADADO_01598 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KHCADADO_01599 4.5e-22 ykzE
KHCADADO_01600 1.2e-10 ydfR S Protein of unknown function (DUF421)
KHCADADO_01601 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
KHCADADO_01602 7e-156 htpX O Belongs to the peptidase M48B family
KHCADADO_01603 1.5e-124 ykrK S Domain of unknown function (DUF1836)
KHCADADO_01604 1.9e-26 sspD S small acid-soluble spore protein
KHCADADO_01605 8.2e-117 rsgI S Anti-sigma factor N-terminus
KHCADADO_01606 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHCADADO_01607 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KHCADADO_01608 1.4e-116 ykoX S membrane-associated protein
KHCADADO_01609 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
KHCADADO_01610 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KHCADADO_01611 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KHCADADO_01612 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KHCADADO_01613 0.0 ykoS
KHCADADO_01614 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
KHCADADO_01615 3.7e-99 ykoP G polysaccharide deacetylase
KHCADADO_01616 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KHCADADO_01617 1.3e-81 mhqR K transcriptional
KHCADADO_01618 6.9e-26 ykoL
KHCADADO_01619 5.9e-18
KHCADADO_01620 1.4e-53 tnrA K transcriptional
KHCADADO_01621 2.2e-222 mgtE P Acts as a magnesium transporter
KHCADADO_01624 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
KHCADADO_01625 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
KHCADADO_01626 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
KHCADADO_01627 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_01628 7.9e-111 ykoF S YKOF-related Family
KHCADADO_01629 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
KHCADADO_01630 4.6e-311 P ABC transporter, ATP-binding protein
KHCADADO_01631 1.8e-136 ykoC P Cobalt transport protein
KHCADADO_01632 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KHCADADO_01633 1.7e-176 isp O Belongs to the peptidase S8 family
KHCADADO_01634 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHCADADO_01635 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
KHCADADO_01637 8.4e-72 ohrB O Organic hydroperoxide resistance protein
KHCADADO_01638 3.9e-75 ohrR K COG1846 Transcriptional regulators
KHCADADO_01639 1.3e-70 ohrA O Organic hydroperoxide resistance protein
KHCADADO_01640 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KHCADADO_01641 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHCADADO_01642 1.4e-110 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KHCADADO_01643 1.8e-38 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KHCADADO_01644 1.1e-50 ykkD P Multidrug resistance protein
KHCADADO_01645 3.5e-55 ykkC P Multidrug resistance protein
KHCADADO_01646 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KHCADADO_01647 1e-98 ykkA S Protein of unknown function (DUF664)
KHCADADO_01648 5.4e-130 ykjA S Protein of unknown function (DUF421)
KHCADADO_01649 1e-07
KHCADADO_01650 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KHCADADO_01651 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KHCADADO_01652 5.3e-161 ykgA E Amidinotransferase
KHCADADO_01653 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
KHCADADO_01654 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
KHCADADO_01655 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KHCADADO_01656 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KHCADADO_01657 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KHCADADO_01659 0.0 dppE E ABC transporter substrate-binding protein
KHCADADO_01660 3.4e-191 dppD P Belongs to the ABC transporter superfamily
KHCADADO_01661 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHCADADO_01662 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHCADADO_01663 7.9e-154 dppA E D-aminopeptidase
KHCADADO_01664 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
KHCADADO_01665 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHCADADO_01667 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KHCADADO_01668 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHCADADO_01670 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KHCADADO_01671 9.4e-242 steT E amino acid
KHCADADO_01672 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KHCADADO_01673 5.8e-175 pit P phosphate transporter
KHCADADO_01674 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KHCADADO_01675 6.7e-23 spoIISB S Stage II sporulation protein SB
KHCADADO_01676 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KHCADADO_01677 9.3e-40 xhlB S SPP1 phage holin
KHCADADO_01678 2.8e-39 xhlA S Haemolysin XhlA
KHCADADO_01679 1.2e-154 xepA
KHCADADO_01680 1.7e-23 xkdX
KHCADADO_01681 2.6e-55 xkdW S XkdW protein
KHCADADO_01682 0.0
KHCADADO_01683 6.7e-41
KHCADADO_01684 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KHCADADO_01685 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KHCADADO_01686 9.6e-71 xkdS S Protein of unknown function (DUF2634)
KHCADADO_01687 2.1e-39 xkdR S Protein of unknown function (DUF2577)
KHCADADO_01688 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
KHCADADO_01689 3.7e-122 xkdP S Lysin motif
KHCADADO_01690 0.0 xkdO L Transglycosylase SLT domain
KHCADADO_01691 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
KHCADADO_01692 1.1e-46 xkdM S Phage tail tube protein
KHCADADO_01693 2.5e-256 xkdK S Phage tail sheath C-terminal domain
KHCADADO_01694 1.9e-77 xkdJ
KHCADADO_01695 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
KHCADADO_01696 8.7e-65 yqbH S Domain of unknown function (DUF3599)
KHCADADO_01697 5.5e-65 yqbG S Protein of unknown function (DUF3199)
KHCADADO_01698 5.8e-169 xkdG S Phage capsid family
KHCADADO_01699 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KHCADADO_01700 5.4e-286 yqbA S portal protein
KHCADADO_01701 9.6e-255 xtmB S phage terminase, large subunit
KHCADADO_01702 4.8e-140 xtmA L phage terminase small subunit
KHCADADO_01703 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KHCADADO_01704 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
KHCADADO_01707 6.4e-119 xkdC L Bacterial dnaA protein
KHCADADO_01708 5.9e-157 xkdB K sequence-specific DNA binding
KHCADADO_01710 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
KHCADADO_01711 1.6e-111 xkdA E IrrE N-terminal-like domain
KHCADADO_01712 4.4e-160 ydbD P Catalase
KHCADADO_01713 4.2e-112 yjqB S Pfam:DUF867
KHCADADO_01714 2.1e-61 yjqA S Bacterial PH domain
KHCADADO_01715 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
KHCADADO_01716 6.3e-41 S YCII-related domain
KHCADADO_01718 2.1e-213 S response regulator aspartate phosphatase
KHCADADO_01719 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
KHCADADO_01720 3.3e-80 yjoA S DinB family
KHCADADO_01721 4.3e-130 MA20_18170 S membrane transporter protein
KHCADADO_01722 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KHCADADO_01723 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KHCADADO_01724 2.3e-184 exuR K transcriptional
KHCADADO_01725 3.7e-227 exuT G Sugar (and other) transporter
KHCADADO_01726 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_01727 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KHCADADO_01728 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KHCADADO_01729 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KHCADADO_01730 5.8e-250 yjmB G symporter YjmB
KHCADADO_01731 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
KHCADADO_01732 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
KHCADADO_01733 7.1e-66 yjlC S Protein of unknown function (DUF1641)
KHCADADO_01734 2.8e-93 yjlB S Cupin domain
KHCADADO_01735 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
KHCADADO_01736 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
KHCADADO_01737 1.9e-122 ybbM S transport system, permease component
KHCADADO_01738 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KHCADADO_01739 8.2e-30
KHCADADO_01740 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KHCADADO_01741 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KHCADADO_01743 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KHCADADO_01744 8.7e-07 S Domain of unknown function (DUF4352)
KHCADADO_01745 4.3e-95 yjgD S Protein of unknown function (DUF1641)
KHCADADO_01746 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KHCADADO_01747 8.9e-104 yjgB S Domain of unknown function (DUF4309)
KHCADADO_01748 1.2e-45 T PhoQ Sensor
KHCADADO_01749 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
KHCADADO_01750 3.6e-21 yjfB S Putative motility protein
KHCADADO_01751 5.5e-83 S Protein of unknown function (DUF2690)
KHCADADO_01752 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
KHCADADO_01754 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KHCADADO_01755 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
KHCADADO_01756 4.2e-29 S Domain of unknown function (DUF4177)
KHCADADO_01757 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHCADADO_01759 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
KHCADADO_01760 4.8e-51 yjdF S Protein of unknown function (DUF2992)
KHCADADO_01761 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KHCADADO_01762 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KHCADADO_01763 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KHCADADO_01765 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
KHCADADO_01766 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
KHCADADO_01767 1.1e-92 yqaS L DNA packaging
KHCADADO_01768 4.1e-49 S YjcQ protein
KHCADADO_01769 1.6e-72 yjcP
KHCADADO_01770 8.5e-81 L Transposase
KHCADADO_01773 2.6e-44 yjcN
KHCADADO_01774 2.1e-190 S Putative amidase domain
KHCADADO_01777 1.1e-212 yjcL S Protein of unknown function (DUF819)
KHCADADO_01778 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
KHCADADO_01779 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KHCADADO_01780 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KHCADADO_01781 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
KHCADADO_01782 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KHCADADO_01783 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHCADADO_01784 1.7e-38
KHCADADO_01785 0.0 yjcD 3.6.4.12 L DNA helicase
KHCADADO_01786 2.9e-38 spoVIF S Stage VI sporulation protein F
KHCADADO_01789 8.7e-57 yjcA S Protein of unknown function (DUF1360)
KHCADADO_01790 2.3e-55 cotV S Spore Coat Protein X and V domain
KHCADADO_01791 3e-32 cotW
KHCADADO_01792 6.4e-77 cotX S Spore Coat Protein X and V domain
KHCADADO_01793 3.4e-96 cotY S Spore coat protein Z
KHCADADO_01794 5.2e-83 cotZ S Spore coat protein
KHCADADO_01795 5.9e-54 yjbX S Spore coat protein
KHCADADO_01796 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KHCADADO_01797 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KHCADADO_01798 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KHCADADO_01799 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KHCADADO_01800 3e-30 thiS H thiamine diphosphate biosynthetic process
KHCADADO_01801 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
KHCADADO_01802 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KHCADADO_01803 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KHCADADO_01804 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KHCADADO_01805 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KHCADADO_01806 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHCADADO_01807 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHCADADO_01808 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
KHCADADO_01809 7.1e-62 yjbL S Belongs to the UPF0738 family
KHCADADO_01810 2.4e-101 yjbK S protein conserved in bacteria
KHCADADO_01811 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KHCADADO_01812 3.7e-72 yjbI S Bacterial-like globin
KHCADADO_01813 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KHCADADO_01815 1.8e-20
KHCADADO_01816 0.0 pepF E oligoendopeptidase F
KHCADADO_01817 2.3e-223 yjbF S Competence protein
KHCADADO_01818 2.8e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KHCADADO_01819 2e-40 yjbE P Integral membrane protein TerC family
KHCADADO_01820 3.1e-63 yjbE P Integral membrane protein TerC family
KHCADADO_01821 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KHCADADO_01822 4.5e-32 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHCADADO_01823 8.1e-61 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHCADADO_01824 8.6e-196 yjbB EGP Major Facilitator Superfamily
KHCADADO_01825 5.5e-172 oppF E Belongs to the ABC transporter superfamily
KHCADADO_01826 3e-198 oppD P Belongs to the ABC transporter superfamily
KHCADADO_01827 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHCADADO_01828 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHCADADO_01829 0.0 oppA E ABC transporter substrate-binding protein
KHCADADO_01830 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KHCADADO_01831 5e-147 yjbA S Belongs to the UPF0736 family
KHCADADO_01832 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHCADADO_01833 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHCADADO_01834 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KHCADADO_01835 6.5e-187 appF E Belongs to the ABC transporter superfamily
KHCADADO_01836 1.8e-184 appD P Belongs to the ABC transporter superfamily
KHCADADO_01837 7.8e-151 yjaZ O Zn-dependent protease
KHCADADO_01838 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KHCADADO_01839 8.3e-134 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHCADADO_01840 2.7e-22 yjzB
KHCADADO_01841 7.3e-26 comZ S ComZ
KHCADADO_01842 1.1e-183 med S Transcriptional activator protein med
KHCADADO_01843 7.3e-103 yjaV
KHCADADO_01844 6.2e-142 yjaU I carboxylic ester hydrolase activity
KHCADADO_01845 2.3e-16 yjzD S Protein of unknown function (DUF2929)
KHCADADO_01846 9.5e-28 yjzC S YjzC-like protein
KHCADADO_01847 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHCADADO_01848 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KHCADADO_01849 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KHCADADO_01850 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KHCADADO_01851 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KHCADADO_01852 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KHCADADO_01853 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KHCADADO_01854 1.7e-88 norB G Major Facilitator Superfamily
KHCADADO_01855 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
KHCADADO_01856 1.5e-22 pilT S Proteolipid membrane potential modulator
KHCADADO_01857 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
KHCADADO_01858 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KHCADADO_01859 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KHCADADO_01860 1.2e-17 S Protein of unknown function (DUF3813)
KHCADADO_01861 1.9e-72 ipi S Intracellular proteinase inhibitor
KHCADADO_01862 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KHCADADO_01863 8.4e-159 yitS S protein conserved in bacteria
KHCADADO_01864 2.2e-311 nprB 3.4.24.28 E Peptidase M4
KHCADADO_01865 1.4e-44 yitR S Domain of unknown function (DUF3784)
KHCADADO_01866 2e-95
KHCADADO_01867 1.5e-58 K Transcriptional regulator PadR-like family
KHCADADO_01868 1.5e-97 S Sporulation delaying protein SdpA
KHCADADO_01869 2.8e-171
KHCADADO_01870 8.5e-94
KHCADADO_01871 4e-161 cvfB S protein conserved in bacteria
KHCADADO_01872 8.6e-55 yajQ S Belongs to the UPF0234 family
KHCADADO_01873 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KHCADADO_01874 2e-82 yjcF S Acetyltransferase (GNAT) domain
KHCADADO_01875 1.8e-161 yitH K Acetyltransferase (GNAT) domain
KHCADADO_01876 4e-229 yitG EGP Major facilitator Superfamily
KHCADADO_01877 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KHCADADO_01878 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHCADADO_01879 1.9e-141 yitD 4.4.1.19 S synthase
KHCADADO_01880 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
KHCADADO_01881 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KHCADADO_01882 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KHCADADO_01883 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
KHCADADO_01884 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KHCADADO_01885 4e-36 mcbG S Pentapeptide repeats (9 copies)
KHCADADO_01886 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KHCADADO_01887 6.4e-108 argO S Lysine exporter protein LysE YggA
KHCADADO_01888 1.3e-93 yisT S DinB family
KHCADADO_01889 1.1e-189 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
KHCADADO_01890 2.4e-184 purR K helix_turn _helix lactose operon repressor
KHCADADO_01891 1.2e-160 yisR K Transcriptional regulator
KHCADADO_01892 4e-243 yisQ V Mate efflux family protein
KHCADADO_01893 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KHCADADO_01894 2.1e-88 yizA S Damage-inducible protein DinB
KHCADADO_01895 0.0 asnO 6.3.5.4 E Asparagine synthase
KHCADADO_01896 7.2e-106 yisN S Protein of unknown function (DUF2777)
KHCADADO_01897 0.0 wprA O Belongs to the peptidase S8 family
KHCADADO_01898 3e-57 yisL S UPF0344 protein
KHCADADO_01899 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KHCADADO_01900 2.3e-92 cotH M Spore Coat
KHCADADO_01901 1.5e-22 yisI S Spo0E like sporulation regulatory protein
KHCADADO_01902 1.9e-33 gerPA S Spore germination protein
KHCADADO_01903 4e-34 gerPB S cell differentiation
KHCADADO_01904 1.8e-54 gerPC S Spore germination protein
KHCADADO_01905 6.3e-24 gerPD S Spore germination protein
KHCADADO_01906 3e-66 gerPE S Spore germination protein GerPE
KHCADADO_01907 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
KHCADADO_01908 6e-51 yisB V COG1403 Restriction endonuclease
KHCADADO_01909 0.0 sbcC L COG0419 ATPase involved in DNA repair
KHCADADO_01910 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KHCADADO_01911 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KHCADADO_01912 3.6e-174 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KHCADADO_01913 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KHCADADO_01914 2.2e-78 yhjR S Rubrerythrin
KHCADADO_01915 2e-36 yhjQ C COG1145 Ferredoxin
KHCADADO_01916 0.0 S Sugar transport-related sRNA regulator N-term
KHCADADO_01917 3.1e-215 EGP Transmembrane secretion effector
KHCADADO_01918 3.8e-202 abrB S membrane
KHCADADO_01919 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
KHCADADO_01920 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
KHCADADO_01921 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
KHCADADO_01922 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
KHCADADO_01923 6.9e-215 glcP G Major Facilitator Superfamily
KHCADADO_01924 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
KHCADADO_01925 1.1e-286 yhjG CH FAD binding domain
KHCADADO_01926 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KHCADADO_01927 9.1e-110 yhjE S SNARE associated Golgi protein
KHCADADO_01928 5e-60 yhjD
KHCADADO_01929 6.9e-27 yhjC S Protein of unknown function (DUF3311)
KHCADADO_01930 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHCADADO_01931 7.8e-42 yhjA S Excalibur calcium-binding domain
KHCADADO_01932 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
KHCADADO_01933 4.2e-109 comK K Competence transcription factor
KHCADADO_01934 1.3e-32 yhzC S IDEAL
KHCADADO_01935 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHCADADO_01936 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KHCADADO_01937 1.7e-182 hemAT NT chemotaxis protein
KHCADADO_01938 5e-91 bioY S BioY family
KHCADADO_01939 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KHCADADO_01940 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
KHCADADO_01941 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KHCADADO_01942 4.3e-159 yfmC M Periplasmic binding protein
KHCADADO_01943 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
KHCADADO_01944 9.2e-80 VY92_01935 K acetyltransferase
KHCADADO_01945 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KHCADADO_01946 7.6e-132 yhfN 3.4.24.84 O Peptidase M48
KHCADADO_01947 1.5e-93 yhfN 3.4.24.84 O Peptidase M48
KHCADADO_01948 1.9e-65 yhfM
KHCADADO_01949 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KHCADADO_01950 2.6e-112 yhfK GM NmrA-like family
KHCADADO_01951 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
KHCADADO_01952 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KHCADADO_01953 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHCADADO_01954 1.7e-72 3.4.13.21 S ASCH
KHCADADO_01955 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KHCADADO_01956 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
KHCADADO_01957 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHCADADO_01958 1e-238 yhgE S YhgE Pip N-terminal domain protein
KHCADADO_01959 1.4e-101 yhgD K Transcriptional regulator
KHCADADO_01960 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KHCADADO_01961 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KHCADADO_01962 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KHCADADO_01963 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KHCADADO_01964 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KHCADADO_01965 7.5e-17 1.15.1.2 C Rubrerythrin
KHCADADO_01966 4.2e-248 yhfA C membrane
KHCADADO_01967 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KHCADADO_01968 4.8e-115 ecsC S EcsC protein family
KHCADADO_01969 1.8e-215 ecsB U ABC transporter
KHCADADO_01970 4.6e-137 ecsA V transporter (ATP-binding protein)
KHCADADO_01971 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KHCADADO_01972 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHCADADO_01973 3.6e-80 trpP S Tryptophan transporter TrpP
KHCADADO_01974 7e-39 yhaH S YtxH-like protein
KHCADADO_01975 1e-113 hpr K Negative regulator of protease production and sporulation
KHCADADO_01976 1.3e-54 yhaI S Protein of unknown function (DUF1878)
KHCADADO_01977 3.2e-37 yhaK S Putative zincin peptidase
KHCADADO_01978 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KHCADADO_01979 1.6e-21 yhaL S Sporulation protein YhaL
KHCADADO_01980 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KHCADADO_01981 0.0 yhaN L AAA domain
KHCADADO_01982 3.6e-227 yhaO L DNA repair exonuclease
KHCADADO_01983 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KHCADADO_01984 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
KHCADADO_01985 1.1e-26 S YhzD-like protein
KHCADADO_01986 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
KHCADADO_01988 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KHCADADO_01989 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
KHCADADO_01990 7.1e-294 hemZ H coproporphyrinogen III oxidase
KHCADADO_01991 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
KHCADADO_01992 3.1e-206 yhaZ L DNA alkylation repair enzyme
KHCADADO_01993 9.5e-48 yheA S Belongs to the UPF0342 family
KHCADADO_01994 6.7e-204 yheB S Belongs to the UPF0754 family
KHCADADO_01995 4.3e-216 yheC HJ YheC/D like ATP-grasp
KHCADADO_01996 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KHCADADO_01997 1.3e-36 yheE S Family of unknown function (DUF5342)
KHCADADO_01998 6.3e-28 sspB S spore protein
KHCADADO_01999 3.7e-111 yheG GM NAD(P)H-binding
KHCADADO_02000 6.7e-240 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KHCADADO_02001 5.9e-110 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KHCADADO_02002 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KHCADADO_02003 3.4e-84 nhaX T Belongs to the universal stress protein A family
KHCADADO_02004 2.2e-233 nhaC C Na H antiporter
KHCADADO_02005 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KHCADADO_02006 1.7e-151 yheN G deacetylase
KHCADADO_02007 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KHCADADO_02008 6.6e-204 yhdY M Mechanosensitive ion channel
KHCADADO_02010 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KHCADADO_02011 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHCADADO_02012 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHCADADO_02013 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KHCADADO_02014 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
KHCADADO_02015 4.1e-74 cueR K transcriptional
KHCADADO_02016 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KHCADADO_02017 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KHCADADO_02018 1.5e-191 yhdN C Aldo keto reductase
KHCADADO_02019 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KHCADADO_02020 6.6e-201 yhdL S Sigma factor regulator N-terminal
KHCADADO_02021 8.1e-45 yhdK S Sigma-M inhibitor protein
KHCADADO_02022 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHCADADO_02023 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KHCADADO_02024 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KHCADADO_02025 3.4e-250 yhdG E amino acid
KHCADADO_02026 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHCADADO_02027 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
KHCADADO_02028 3.8e-162 citR K Transcriptional regulator
KHCADADO_02029 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KHCADADO_02030 1.4e-66 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KHCADADO_02031 6.3e-182 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KHCADADO_02032 2.1e-276 ycgB S Stage V sporulation protein R
KHCADADO_02033 8.7e-239 ygxB M Conserved TM helix
KHCADADO_02034 3.5e-76 nsrR K Transcriptional regulator
KHCADADO_02035 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KHCADADO_02036 4.8e-54 yhdC S Protein of unknown function (DUF3889)
KHCADADO_02037 1.2e-38 yhdB S YhdB-like protein
KHCADADO_02038 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
KHCADADO_02039 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KHCADADO_02040 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
KHCADADO_02041 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KHCADADO_02042 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KHCADADO_02043 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHCADADO_02044 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KHCADADO_02045 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KHCADADO_02046 2.6e-194 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHCADADO_02047 2.5e-59 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHCADADO_02048 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KHCADADO_02049 4.6e-120 yhcW 5.4.2.6 S hydrolase
KHCADADO_02050 9.9e-68 yhcV S COG0517 FOG CBS domain
KHCADADO_02051 9.3e-68 yhcU S Family of unknown function (DUF5365)
KHCADADO_02052 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHCADADO_02053 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KHCADADO_02054 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
KHCADADO_02055 5.2e-100 yhcQ M Spore coat protein
KHCADADO_02056 2.5e-167 yhcP
KHCADADO_02057 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KHCADADO_02058 3.7e-44 yhcM
KHCADADO_02059 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHCADADO_02060 3.5e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KHCADADO_02061 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
KHCADADO_02062 1e-30 cspB K Cold-shock protein
KHCADADO_02063 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KHCADADO_02064 2.6e-166 yhcH V ABC transporter, ATP-binding protein
KHCADADO_02065 1.6e-123 yhcG V ABC transporter, ATP-binding protein
KHCADADO_02066 6.6e-60 yhcF K Transcriptional regulator
KHCADADO_02067 7.8e-55
KHCADADO_02068 2.8e-37 yhcC
KHCADADO_02069 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
KHCADADO_02070 3.1e-271 yhcA EGP Major facilitator Superfamily
KHCADADO_02071 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
KHCADADO_02072 2.2e-76 yhbI K DNA-binding transcription factor activity
KHCADADO_02073 2.5e-225 yhbH S Belongs to the UPF0229 family
KHCADADO_02074 0.0 prkA T Ser protein kinase
KHCADADO_02075 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KHCADADO_02076 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KHCADADO_02077 1.2e-109 yhbD K Protein of unknown function (DUF4004)
KHCADADO_02078 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KHCADADO_02079 4.4e-177 yhbB S Putative amidase domain
KHCADADO_02080 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHCADADO_02081 7.9e-114 yhzB S B3/4 domain
KHCADADO_02083 4.4e-29 K Transcriptional regulator
KHCADADO_02084 4.1e-78 ygaO
KHCADADO_02085 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHCADADO_02087 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KHCADADO_02088 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KHCADADO_02089 1.7e-171 ssuA M Sulfonate ABC transporter
KHCADADO_02090 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KHCADADO_02091 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KHCADADO_02093 1.9e-266 ygaK C Berberine and berberine like
KHCADADO_02094 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KHCADADO_02096 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KHCADADO_02097 3e-27
KHCADADO_02098 2.7e-143 spo0M S COG4326 Sporulation control protein
KHCADADO_02102 2e-08
KHCADADO_02110 7.8e-08
KHCADADO_02119 2e-08
KHCADADO_02126 1.3e-09
KHCADADO_02127 7.8e-08
KHCADADO_02136 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KHCADADO_02137 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHCADADO_02138 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KHCADADO_02139 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KHCADADO_02140 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KHCADADO_02141 9.9e-77 tspO T membrane
KHCADADO_02142 1.8e-206 cotI S Spore coat protein
KHCADADO_02143 1.8e-217 cotSA M Glycosyl transferases group 1
KHCADADO_02144 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
KHCADADO_02146 3.6e-235 ytcC M Glycosyltransferase Family 4
KHCADADO_02147 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
KHCADADO_02148 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHCADADO_02149 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
KHCADADO_02150 2.6e-132 dksA T COG1734 DnaK suppressor protein
KHCADADO_02151 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
KHCADADO_02152 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KHCADADO_02153 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KHCADADO_02154 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KHCADADO_02155 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KHCADADO_02156 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KHCADADO_02157 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
KHCADADO_02158 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KHCADADO_02159 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KHCADADO_02160 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KHCADADO_02161 1.1e-24 S Domain of Unknown Function (DUF1540)
KHCADADO_02162 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KHCADADO_02163 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
KHCADADO_02164 3.6e-41 rpmE2 J Ribosomal protein L31
KHCADADO_02165 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KHCADADO_02166 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHCADADO_02167 3.6e-73 ytkA S YtkA-like
KHCADADO_02169 2.1e-76 dps P Belongs to the Dps family
KHCADADO_02170 5.4e-63 ytkC S Bacteriophage holin family
KHCADADO_02171 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KHCADADO_02172 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KHCADADO_02173 1.4e-144 ytlC P ABC transporter
KHCADADO_02174 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KHCADADO_02175 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KHCADADO_02176 1.2e-38 ytmB S Protein of unknown function (DUF2584)
KHCADADO_02177 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KHCADADO_02178 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHCADADO_02179 0.0 asnB 6.3.5.4 E Asparagine synthase
KHCADADO_02180 1.3e-250 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KHCADADO_02181 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KHCADADO_02182 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
KHCADADO_02183 5.7e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KHCADADO_02184 3.3e-106 ytqB J Putative rRNA methylase
KHCADADO_02185 2.1e-190 yhcC S Fe-S oxidoreductase
KHCADADO_02186 6.7e-41 ytzC S Protein of unknown function (DUF2524)
KHCADADO_02188 5.1e-66 ytrA K GntR family transcriptional regulator
KHCADADO_02189 1.1e-161 ytrB P abc transporter atp-binding protein
KHCADADO_02190 6.1e-169 P ABC-2 family transporter protein
KHCADADO_02191 5.9e-148
KHCADADO_02192 3.1e-127 ytrE V ABC transporter, ATP-binding protein
KHCADADO_02193 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KHCADADO_02194 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_02195 5.6e-186 T PhoQ Sensor
KHCADADO_02196 1.1e-138 bceA V ABC transporter, ATP-binding protein
KHCADADO_02197 0.0 bceB V ABC transporter (permease)
KHCADADO_02198 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
KHCADADO_02199 2.1e-211 yttB EGP Major facilitator Superfamily
KHCADADO_02200 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KHCADADO_02201 7.7e-55 ytvB S Protein of unknown function (DUF4257)
KHCADADO_02202 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHCADADO_02203 2.1e-51 ytwF P Sulfurtransferase
KHCADADO_02204 1.1e-206 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KHCADADO_02205 1.5e-144 amyC P ABC transporter (permease)
KHCADADO_02206 3.7e-168 amyD P ABC transporter
KHCADADO_02207 5.5e-118 msmE G Bacterial extracellular solute-binding protein
KHCADADO_02208 1.9e-121 msmE G Bacterial extracellular solute-binding protein
KHCADADO_02209 2.3e-190 msmR K Transcriptional regulator
KHCADADO_02210 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
KHCADADO_02211 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KHCADADO_02212 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KHCADADO_02213 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KHCADADO_02214 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KHCADADO_02215 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KHCADADO_02216 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
KHCADADO_02217 5.8e-132 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
KHCADADO_02218 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
KHCADADO_02219 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
KHCADADO_02220 0.0 ytdP K Transcriptional regulator
KHCADADO_02221 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KHCADADO_02222 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KHCADADO_02223 4.6e-73 yteS G transport
KHCADADO_02224 2.6e-249 yteT S Oxidoreductase family, C-terminal alpha/beta domain
KHCADADO_02225 4.8e-117 yteU S Integral membrane protein
KHCADADO_02226 3.1e-26 yteV S Sporulation protein Cse60
KHCADADO_02227 9.8e-09 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KHCADADO_02228 9.9e-261 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KHCADADO_02229 8.2e-232 ytfP S HI0933-like protein
KHCADADO_02230 1.3e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KHCADADO_02231 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KHCADADO_02232 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KHCADADO_02233 4.3e-132 ythP V ABC transporter
KHCADADO_02234 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
KHCADADO_02235 7.2e-226 pbuO S permease
KHCADADO_02236 7.1e-272 pepV 3.5.1.18 E Dipeptidase
KHCADADO_02237 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KHCADADO_02238 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KHCADADO_02239 1.3e-165 ytlQ
KHCADADO_02240 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KHCADADO_02241 3e-221 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KHCADADO_02242 4.4e-174 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KHCADADO_02243 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
KHCADADO_02244 2e-45 ytzH S YtzH-like protein
KHCADADO_02245 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KHCADADO_02246 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KHCADADO_02247 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KHCADADO_02248 9.8e-52 ytzB S small secreted protein
KHCADADO_02249 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KHCADADO_02250 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KHCADADO_02251 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KHCADADO_02252 9.8e-149 ytpQ S Belongs to the UPF0354 family
KHCADADO_02253 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHCADADO_02254 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KHCADADO_02255 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KHCADADO_02256 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHCADADO_02257 6.6e-17 ytxH S COG4980 Gas vesicle protein
KHCADADO_02258 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
KHCADADO_02259 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KHCADADO_02260 1.7e-182 ccpA K catabolite control protein A
KHCADADO_02261 7.1e-147 motA N flagellar motor
KHCADADO_02262 6.6e-111 motS N Flagellar motor protein
KHCADADO_02263 1.9e-225 acuC BQ histone deacetylase
KHCADADO_02264 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
KHCADADO_02265 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KHCADADO_02266 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KHCADADO_02267 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHCADADO_02269 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHCADADO_02270 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KHCADADO_02271 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KHCADADO_02272 3.4e-109 yttP K Transcriptional regulator
KHCADADO_02273 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KHCADADO_02274 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KHCADADO_02275 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
KHCADADO_02276 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
KHCADADO_02277 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHCADADO_02278 2e-29 sspB S spore protein
KHCADADO_02279 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KHCADADO_02280 0.0 ytcJ S amidohydrolase
KHCADADO_02281 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHCADADO_02282 2.4e-181 sppA OU signal peptide peptidase SppA
KHCADADO_02283 1.3e-87 yteJ S RDD family
KHCADADO_02284 5.6e-116 ytfI S Protein of unknown function (DUF2953)
KHCADADO_02285 8.7e-70 ytfJ S Sporulation protein YtfJ
KHCADADO_02286 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KHCADADO_02287 7e-165 ytxK 2.1.1.72 L DNA methylase
KHCADADO_02288 4.1e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHCADADO_02289 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KHCADADO_02290 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KHCADADO_02291 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
KHCADADO_02293 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHCADADO_02294 1.7e-130 ytkL S Belongs to the UPF0173 family
KHCADADO_02295 2.9e-173 ytlI K LysR substrate binding domain
KHCADADO_02296 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
KHCADADO_02297 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
KHCADADO_02298 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
KHCADADO_02299 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
KHCADADO_02300 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
KHCADADO_02301 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KHCADADO_02302 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHCADADO_02303 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
KHCADADO_02304 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHCADADO_02305 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
KHCADADO_02306 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
KHCADADO_02307 1.2e-158 ytnM S membrane transporter protein
KHCADADO_02308 8e-241 ytoI K transcriptional regulator containing CBS domains
KHCADADO_02309 2.4e-47 ytpI S YtpI-like protein
KHCADADO_02310 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KHCADADO_02311 9.2e-29
KHCADADO_02312 8.2e-69 ytrI
KHCADADO_02313 3.2e-56 ytrH S Sporulation protein YtrH
KHCADADO_02314 0.0 dnaE 2.7.7.7 L DNA polymerase
KHCADADO_02315 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
KHCADADO_02316 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHCADADO_02317 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KHCADADO_02318 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KHCADADO_02319 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KHCADADO_02320 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KHCADADO_02321 2.6e-192 ytvI S sporulation integral membrane protein YtvI
KHCADADO_02322 4.7e-71 yeaL S membrane
KHCADADO_02323 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KHCADADO_02324 1.8e-242 icd 1.1.1.42 C isocitrate
KHCADADO_02325 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KHCADADO_02326 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_02327 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KHCADADO_02328 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHCADADO_02329 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KHCADADO_02330 1.1e-107 ytaF P Probably functions as a manganese efflux pump
KHCADADO_02331 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHCADADO_02332 8.9e-161 ytbE S reductase
KHCADADO_02333 4.9e-205 ytbD EGP Major facilitator Superfamily
KHCADADO_02334 9.9e-67 ytcD K Transcriptional regulator
KHCADADO_02335 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHCADADO_02336 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KHCADADO_02337 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHCADADO_02338 3.5e-266 dnaB L Membrane attachment protein
KHCADADO_02339 3e-173 dnaI L Primosomal protein DnaI
KHCADADO_02340 4.9e-111 ytxB S SNARE associated Golgi protein
KHCADADO_02341 3.8e-26 ytxC S YtxC-like family
KHCADADO_02342 2.4e-118 ytxC S YtxC-like family
KHCADADO_02343 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHCADADO_02344 1.5e-149 ysaA S HAD-hyrolase-like
KHCADADO_02345 0.0 lytS 2.7.13.3 T Histidine kinase
KHCADADO_02346 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
KHCADADO_02347 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KHCADADO_02348 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KHCADADO_02350 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHCADADO_02351 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KHCADADO_02352 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHCADADO_02353 7.5e-45 ysdA S Membrane
KHCADADO_02354 9.2e-68 ysdB S Sigma-w pathway protein YsdB
KHCADADO_02355 2.4e-22 ysdC G COG1363 Cellulase M and related proteins
KHCADADO_02356 2.4e-175 ysdC G COG1363 Cellulase M and related proteins
KHCADADO_02357 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KHCADADO_02358 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KHCADADO_02359 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KHCADADO_02360 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KHCADADO_02361 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KHCADADO_02362 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KHCADADO_02363 2.8e-254 araN G carbohydrate transport
KHCADADO_02364 1.4e-167 araP G carbohydrate transport
KHCADADO_02365 3.4e-144 araQ G transport system permease
KHCADADO_02366 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KHCADADO_02367 0.0 cstA T Carbon starvation protein
KHCADADO_02369 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
KHCADADO_02370 5.6e-258 glcF C Glycolate oxidase
KHCADADO_02371 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
KHCADADO_02372 4.4e-208 ysfB KT regulator
KHCADADO_02373 2.6e-32 sspI S Belongs to the SspI family
KHCADADO_02374 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHCADADO_02375 2.5e-46 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHCADADO_02376 4.6e-102 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHCADADO_02377 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHCADADO_02378 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHCADADO_02379 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KHCADADO_02380 1.3e-85 cvpA S membrane protein, required for colicin V production
KHCADADO_02381 0.0 polX L COG1796 DNA polymerase IV (family X)
KHCADADO_02382 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KHCADADO_02383 7.3e-68 yshE S membrane
KHCADADO_02384 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KHCADADO_02385 2.7e-100 fadR K Transcriptional regulator
KHCADADO_02386 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KHCADADO_02387 1.2e-135 etfB C Electron transfer flavoprotein
KHCADADO_02388 4.2e-178 etfA C Electron transfer flavoprotein
KHCADADO_02390 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KHCADADO_02391 2e-52 trxA O Belongs to the thioredoxin family
KHCADADO_02392 1.2e-73 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHCADADO_02393 4.1e-217 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHCADADO_02394 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KHCADADO_02395 1.2e-79 yslB S Protein of unknown function (DUF2507)
KHCADADO_02396 2.4e-107 sdhC C succinate dehydrogenase
KHCADADO_02397 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KHCADADO_02398 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KHCADADO_02399 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KHCADADO_02400 3.3e-30 gerE K Transcriptional regulator
KHCADADO_02401 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KHCADADO_02402 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KHCADADO_02403 2.9e-196 gerM S COG5401 Spore germination protein
KHCADADO_02404 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KHCADADO_02405 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHCADADO_02406 1.4e-92 ysnB S Phosphoesterase
KHCADADO_02408 9.1e-134 ysnF S protein conserved in bacteria
KHCADADO_02409 7.6e-82 ysnE K acetyltransferase
KHCADADO_02411 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KHCADADO_02412 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
KHCADADO_02413 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KHCADADO_02414 7.4e-19 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHCADADO_02415 7.2e-264 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHCADADO_02416 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KHCADADO_02417 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KHCADADO_02418 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KHCADADO_02419 2.3e-187 ysoA H Tetratricopeptide repeat
KHCADADO_02420 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KHCADADO_02421 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHCADADO_02422 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KHCADADO_02423 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KHCADADO_02424 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KHCADADO_02425 1.4e-89 ysxD
KHCADADO_02426 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KHCADADO_02427 3.6e-146 hemX O cytochrome C
KHCADADO_02428 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KHCADADO_02429 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KHCADADO_02430 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
KHCADADO_02431 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KHCADADO_02432 1.9e-226 spoVID M stage VI sporulation protein D
KHCADADO_02433 7.3e-74 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHCADADO_02434 2.5e-118 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHCADADO_02435 1.6e-25
KHCADADO_02436 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KHCADADO_02437 4.7e-210 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KHCADADO_02438 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KHCADADO_02439 7.7e-161 spoIIB S Sporulation related domain
KHCADADO_02440 2.8e-102 maf D septum formation protein Maf
KHCADADO_02441 5.9e-126 radC E Belongs to the UPF0758 family
KHCADADO_02442 1.8e-184 mreB D Rod shape-determining protein MreB
KHCADADO_02443 2.8e-157 mreC M Involved in formation and maintenance of cell shape
KHCADADO_02444 1.6e-21 mreD M shape-determining protein
KHCADADO_02445 5.2e-54 mreD M shape-determining protein
KHCADADO_02446 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KHCADADO_02447 2.5e-144 minD D Belongs to the ParA family
KHCADADO_02448 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KHCADADO_02449 9.2e-161 spoIVFB S Stage IV sporulation protein
KHCADADO_02450 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KHCADADO_02451 4.1e-56 ysxB J ribosomal protein
KHCADADO_02452 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KHCADADO_02453 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KHCADADO_02454 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHCADADO_02455 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KHCADADO_02456 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
KHCADADO_02457 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
KHCADADO_02458 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
KHCADADO_02459 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KHCADADO_02460 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KHCADADO_02461 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KHCADADO_02462 9.8e-158 safA M spore coat assembly protein SafA
KHCADADO_02463 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KHCADADO_02464 1.9e-127 yebC K transcriptional regulatory protein
KHCADADO_02465 1.8e-262 alsT E Sodium alanine symporter
KHCADADO_02466 2.6e-35 S Family of unknown function (DUF5412)
KHCADADO_02468 6.5e-119 yrzF T serine threonine protein kinase
KHCADADO_02469 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
KHCADADO_02470 5.3e-253 csbX EGP Major facilitator Superfamily
KHCADADO_02471 1.8e-40 bofC S BofC C-terminal domain
KHCADADO_02472 9.4e-39 bofC S BofC C-terminal domain
KHCADADO_02473 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KHCADADO_02474 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KHCADADO_02475 2.6e-18 yrzS S Protein of unknown function (DUF2905)
KHCADADO_02476 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KHCADADO_02477 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KHCADADO_02478 1.1e-38 yajC U Preprotein translocase subunit YajC
KHCADADO_02479 1.2e-74 yrzE S Protein of unknown function (DUF3792)
KHCADADO_02480 2.2e-114 yrbG S membrane
KHCADADO_02481 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KHCADADO_02482 9.4e-49 yrzD S Post-transcriptional regulator
KHCADADO_02483 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KHCADADO_02484 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KHCADADO_02485 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
KHCADADO_02486 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KHCADADO_02487 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHCADADO_02488 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHCADADO_02489 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHCADADO_02490 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
KHCADADO_02492 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
KHCADADO_02493 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KHCADADO_02494 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KHCADADO_02495 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KHCADADO_02496 1.2e-70 cymR K Transcriptional regulator
KHCADADO_02497 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
KHCADADO_02498 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KHCADADO_02499 1.4e-15 S COG0457 FOG TPR repeat
KHCADADO_02500 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KHCADADO_02501 1.8e-83 yrrD S protein conserved in bacteria
KHCADADO_02502 9.8e-31 yrzR
KHCADADO_02503 8e-08 S Protein of unknown function (DUF3918)
KHCADADO_02504 7.6e-107 glnP P ABC transporter
KHCADADO_02505 3.6e-109 gluC P ABC transporter
KHCADADO_02506 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
KHCADADO_02507 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KHCADADO_02508 1.6e-34 yrrI S AI-2E family transporter
KHCADADO_02509 5.8e-128 yrrI S AI-2E family transporter
KHCADADO_02510 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHCADADO_02511 1.7e-41 yrzL S Belongs to the UPF0297 family
KHCADADO_02512 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHCADADO_02513 1.2e-45 yrzB S Belongs to the UPF0473 family
KHCADADO_02514 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHCADADO_02515 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
KHCADADO_02516 7.8e-174 yegQ O Peptidase U32
KHCADADO_02517 2.7e-246 yegQ O COG0826 Collagenase and related proteases
KHCADADO_02518 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KHCADADO_02519 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHCADADO_02520 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KHCADADO_02521 4.2e-63 yrrS S Protein of unknown function (DUF1510)
KHCADADO_02522 7e-27 yrzA S Protein of unknown function (DUF2536)
KHCADADO_02523 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KHCADADO_02524 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHCADADO_02525 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KHCADADO_02526 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KHCADADO_02527 4.6e-35 yrhC S YrhC-like protein
KHCADADO_02528 1.4e-78 yrhD S Protein of unknown function (DUF1641)
KHCADADO_02529 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KHCADADO_02530 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
KHCADADO_02531 1.8e-142 focA P Formate nitrite
KHCADADO_02534 4.5e-97 yrhH Q methyltransferase
KHCADADO_02535 4.8e-51 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KHCADADO_02536 5.6e-46 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KHCADADO_02537 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KHCADADO_02538 1.5e-46 yrhK S YrhK-like protein
KHCADADO_02539 0.0 yrhL I Acyltransferase family
KHCADADO_02540 1.7e-151 rsiV S Protein of unknown function (DUF3298)
KHCADADO_02541 1.6e-42 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KHCADADO_02542 1.7e-17 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KHCADADO_02543 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
KHCADADO_02544 3.6e-106 yrhP E LysE type translocator
KHCADADO_02545 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KHCADADO_02546 0.0 levR K PTS system fructose IIA component
KHCADADO_02547 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
KHCADADO_02548 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
KHCADADO_02549 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KHCADADO_02550 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KHCADADO_02551 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KHCADADO_02552 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
KHCADADO_02553 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
KHCADADO_02554 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
KHCADADO_02555 4.3e-47 yraB K helix_turn_helix, mercury resistance
KHCADADO_02556 1.1e-49 yraD M Spore coat protein
KHCADADO_02557 2.6e-26 yraE
KHCADADO_02558 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KHCADADO_02559 6.4e-63 yraF M Spore coat protein
KHCADADO_02560 5.3e-37 yraG
KHCADADO_02561 1.3e-66 E Glyoxalase-like domain
KHCADADO_02562 2.4e-61 T sh3 domain protein
KHCADADO_02563 1.7e-60 T sh3 domain protein
KHCADADO_02564 3.2e-155 S Alpha beta hydrolase
KHCADADO_02565 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KHCADADO_02566 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KHCADADO_02568 2.4e-206 yraM S PrpF protein
KHCADADO_02569 1.2e-163 yraN K Transcriptional regulator
KHCADADO_02570 9.5e-226 yraO C Citrate transporter
KHCADADO_02571 4.5e-188 yrpG C Aldo/keto reductase family
KHCADADO_02572 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
KHCADADO_02573 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KHCADADO_02575 3e-125 yrpD S Domain of unknown function, YrpD
KHCADADO_02576 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KHCADADO_02577 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KHCADADO_02578 7.6e-168 aadK G Streptomycin adenylyltransferase
KHCADADO_02579 1.2e-91 yrdA S DinB family
KHCADADO_02580 1.9e-57 S Protein of unknown function (DUF2568)
KHCADADO_02581 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
KHCADADO_02583 4.1e-231 cypA C Cytochrome P450
KHCADADO_02584 4.1e-46 yrdF K ribonuclease inhibitor
KHCADADO_02585 2.2e-79 bkdR K helix_turn_helix ASNC type
KHCADADO_02586 3.3e-138 azlC E AzlC protein
KHCADADO_02587 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
KHCADADO_02588 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
KHCADADO_02590 7.7e-163 gltR K LysR substrate binding domain
KHCADADO_02591 1.3e-66 yodA S tautomerase
KHCADADO_02592 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
KHCADADO_02593 2e-199 trkA P Oxidoreductase
KHCADADO_02594 5.9e-160 yrdQ K Transcriptional regulator
KHCADADO_02595 1.7e-171 yrdR EG EamA-like transporter family
KHCADADO_02596 2.1e-17 S YrzO-like protein
KHCADADO_02597 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KHCADADO_02598 1.4e-83 bltD 2.3.1.57 K FR47-like protein
KHCADADO_02599 3.5e-211 blt EGP Major facilitator Superfamily
KHCADADO_02600 4.8e-151 bltR K helix_turn_helix, mercury resistance
KHCADADO_02601 2.6e-108 yrkC G Cupin domain
KHCADADO_02602 2e-28
KHCADADO_02603 7.8e-39 yrkD S protein conserved in bacteria
KHCADADO_02604 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
KHCADADO_02605 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
KHCADADO_02606 1.8e-203 yrkH P Rhodanese Homology Domain
KHCADADO_02607 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
KHCADADO_02608 2.7e-24 yrkJ S membrane transporter protein
KHCADADO_02609 1.2e-70 yrkJ S membrane transporter protein
KHCADADO_02610 2.8e-79 S Protein of unknown function with HXXEE motif
KHCADADO_02611 1.5e-97 ywrO S Flavodoxin-like fold
KHCADADO_02612 2.3e-104 yrkN K Acetyltransferase (GNAT) family
KHCADADO_02613 8.2e-224 yrkO P Protein of unknown function (DUF418)
KHCADADO_02614 1.1e-127 T Transcriptional regulator
KHCADADO_02615 9e-237 yrkQ T Histidine kinase
KHCADADO_02616 2e-68 psiE S Protein PsiE homolog
KHCADADO_02617 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHCADADO_02618 1.4e-100 yqaB E IrrE N-terminal-like domain
KHCADADO_02619 1e-101 adk 2.7.4.3 F adenylate kinase activity
KHCADADO_02621 1.1e-56 K sequence-specific DNA binding
KHCADADO_02622 6.5e-37 K Helix-turn-helix XRE-family like proteins
KHCADADO_02624 1.2e-103
KHCADADO_02628 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
KHCADADO_02629 2.5e-155 recT L RecT family
KHCADADO_02630 4.7e-123 3.1.3.16 L DnaD domain protein
KHCADADO_02631 5.9e-168 xkdC L IstB-like ATP binding protein
KHCADADO_02633 7.2e-74 rusA L Endodeoxyribonuclease RusA
KHCADADO_02634 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
KHCADADO_02635 1.6e-166
KHCADADO_02636 6.5e-81 L Transposase
KHCADADO_02637 1.1e-15 yqaS L DNA packaging
KHCADADO_02638 2.4e-83 yqaS L DNA packaging
KHCADADO_02639 2.4e-253 S phage terminase, large subunit
KHCADADO_02640 5.9e-296 yqbA S portal protein
KHCADADO_02641 5.7e-169 S Phage Mu protein F like protein
KHCADADO_02642 2e-115
KHCADADO_02643 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KHCADADO_02644 1.9e-167 xkdG S Phage capsid family
KHCADADO_02645 3.6e-51 S YqbF, hypothetical protein domain
KHCADADO_02646 2.1e-67 S Protein of unknown function (DUF3199)
KHCADADO_02647 6.7e-65 yqbH S Domain of unknown function (DUF3599)
KHCADADO_02648 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
KHCADADO_02649 1.4e-77
KHCADADO_02650 3.2e-26
KHCADADO_02651 5.5e-256 xkdK S Phage tail sheath C-terminal domain
KHCADADO_02652 3.6e-76 xkdM S Phage tail tube protein
KHCADADO_02654 1.2e-24 S Phage XkdN-like tail assembly chaperone protein, TAC
KHCADADO_02655 1.8e-31 S Phage XkdN-like tail assembly chaperone protein, TAC
KHCADADO_02656 0.0 xkdO L Transglycosylase SLT domain
KHCADADO_02657 9e-114 xkdP S Lysin motif
KHCADADO_02658 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
KHCADADO_02659 1.8e-38 xkdR S Protein of unknown function (DUF2577)
KHCADADO_02660 9.6e-71 xkdS S Protein of unknown function (DUF2634)
KHCADADO_02661 4.3e-155 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KHCADADO_02662 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KHCADADO_02663 9.6e-40
KHCADADO_02664 2e-221
KHCADADO_02665 4.1e-56 xkdW S XkdW protein
KHCADADO_02666 1.3e-23
KHCADADO_02667 4.8e-165 xepA
KHCADADO_02668 2.6e-68 S Bacteriophage holin family
KHCADADO_02669 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KHCADADO_02672 1.1e-104 S Suppressor of fused protein (SUFU)
KHCADADO_02673 3.8e-277 A Pre-toxin TG
KHCADADO_02676 1.6e-96 S Tetratricopeptide repeat
KHCADADO_02677 1.1e-152 yqcI S YqcI/YcgG family
KHCADADO_02678 1.6e-54 arsR K ArsR family transcriptional regulator
KHCADADO_02679 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHCADADO_02680 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
KHCADADO_02681 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KHCADADO_02682 1.4e-281 cisA2 L Recombinase
KHCADADO_02683 3.2e-36 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHCADADO_02684 1.9e-12 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHCADADO_02685 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
KHCADADO_02686 2.3e-133 yqeB
KHCADADO_02687 1.7e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KHCADADO_02688 3e-45 yqeD S SNARE associated Golgi protein
KHCADADO_02689 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KHCADADO_02690 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
KHCADADO_02692 8.2e-60 yqeG S hydrolase of the HAD superfamily
KHCADADO_02693 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KHCADADO_02694 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHCADADO_02695 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KHCADADO_02696 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHCADADO_02697 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KHCADADO_02698 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KHCADADO_02699 2.9e-139 yqeM Q Methyltransferase
KHCADADO_02700 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHCADADO_02701 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
KHCADADO_02702 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
KHCADADO_02703 0.0 comEC S Competence protein ComEC
KHCADADO_02704 4.1e-15 S YqzM-like protein
KHCADADO_02705 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
KHCADADO_02706 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
KHCADADO_02707 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KHCADADO_02708 6.9e-223 spoIIP M stage II sporulation protein P
KHCADADO_02709 1e-54 yqxA S Protein of unknown function (DUF3679)
KHCADADO_02710 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHCADADO_02711 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
KHCADADO_02712 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KHCADADO_02713 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHCADADO_02714 0.0 dnaK O Heat shock 70 kDa protein
KHCADADO_02715 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KHCADADO_02716 5.4e-175 prmA J Methylates ribosomal protein L11
KHCADADO_02717 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KHCADADO_02718 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KHCADADO_02719 1.6e-158 yqeW P COG1283 Na phosphate symporter
KHCADADO_02720 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KHCADADO_02721 2.5e-61 yqeY S Yqey-like protein
KHCADADO_02722 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KHCADADO_02723 4.3e-122 yqfA S UPF0365 protein
KHCADADO_02724 6e-25 yqfB
KHCADADO_02725 2.7e-45 yqfC S sporulation protein YqfC
KHCADADO_02726 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KHCADADO_02727 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
KHCADADO_02729 0.0 yqfF S membrane-associated HD superfamily hydrolase
KHCADADO_02730 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHCADADO_02731 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KHCADADO_02732 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KHCADADO_02733 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHCADADO_02734 8.4e-19 S YqzL-like protein
KHCADADO_02735 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
KHCADADO_02736 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KHCADADO_02737 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KHCADADO_02738 4.5e-112 ccpN K CBS domain
KHCADADO_02739 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KHCADADO_02740 4.5e-88 yaiI S Belongs to the UPF0178 family
KHCADADO_02741 2.9e-190 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHCADADO_02742 4.1e-139 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHCADADO_02743 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHCADADO_02744 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
KHCADADO_02745 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
KHCADADO_02746 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHCADADO_02747 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KHCADADO_02748 2.9e-14 yqfQ S YqfQ-like protein
KHCADADO_02749 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KHCADADO_02750 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KHCADADO_02751 2.1e-36 yqfT S Protein of unknown function (DUF2624)
KHCADADO_02752 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KHCADADO_02753 1.9e-77 zur P Belongs to the Fur family
KHCADADO_02754 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KHCADADO_02755 4.3e-62 yqfX S membrane
KHCADADO_02756 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KHCADADO_02757 5.2e-47 yqfZ M LysM domain
KHCADADO_02758 2.2e-75 yqgA
KHCADADO_02759 8.5e-134 yqgB S Protein of unknown function (DUF1189)
KHCADADO_02760 4e-73 yqgC S protein conserved in bacteria
KHCADADO_02761 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KHCADADO_02762 2.5e-231 yqgE EGP Major facilitator superfamily
KHCADADO_02763 4.5e-56 pbpA 3.4.16.4 M penicillin-binding protein
KHCADADO_02764 9.8e-311 pbpA 3.4.16.4 M penicillin-binding protein
KHCADADO_02765 5.3e-151 pstS P Phosphate
KHCADADO_02766 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
KHCADADO_02767 4.4e-158 pstA P Phosphate transport system permease
KHCADADO_02768 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHCADADO_02769 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHCADADO_02770 1.9e-75 yqzC S YceG-like family
KHCADADO_02771 9.2e-51 yqzD
KHCADADO_02773 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
KHCADADO_02774 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KHCADADO_02775 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHCADADO_02776 2.5e-09 yqgO
KHCADADO_02777 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KHCADADO_02778 4.3e-33 yqgQ S Protein conserved in bacteria
KHCADADO_02779 5.2e-181 glcK 2.7.1.2 G Glucokinase
KHCADADO_02780 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KHCADADO_02781 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KHCADADO_02782 2.7e-199 yqgU
KHCADADO_02783 6.9e-50 yqgV S Thiamine-binding protein
KHCADADO_02784 8.9e-23 yqgW S Protein of unknown function (DUF2759)
KHCADADO_02785 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KHCADADO_02786 1.8e-37 yqgY S Protein of unknown function (DUF2626)
KHCADADO_02787 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
KHCADADO_02789 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KHCADADO_02790 1.3e-51 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KHCADADO_02791 8.4e-177 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KHCADADO_02792 7.2e-175 corA P Mg2 transporter protein
KHCADADO_02794 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KHCADADO_02795 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
KHCADADO_02796 1.4e-47 comGC U Required for transformation and DNA binding
KHCADADO_02797 4.4e-71 gspH NU protein transport across the cell outer membrane
KHCADADO_02798 1.1e-59 comGE
KHCADADO_02799 5.5e-49 comGF U Putative Competence protein ComGF
KHCADADO_02800 3.7e-42 S ComG operon protein 7
KHCADADO_02801 1.4e-26 yqzE S YqzE-like protein
KHCADADO_02802 7.3e-54 yqzG S Protein of unknown function (DUF3889)
KHCADADO_02803 2.1e-116 yqxM
KHCADADO_02804 6.7e-59 sipW 3.4.21.89 U Signal peptidase
KHCADADO_02805 2.3e-142 tasA S Cell division protein FtsN
KHCADADO_02806 1e-54 sinR K transcriptional
KHCADADO_02807 1.2e-24 sinI S Anti-repressor SinI
KHCADADO_02808 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
KHCADADO_02809 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KHCADADO_02810 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KHCADADO_02811 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHCADADO_02812 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHCADADO_02813 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
KHCADADO_02814 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KHCADADO_02815 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KHCADADO_02816 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
KHCADADO_02817 2.2e-61 yqhP
KHCADADO_02818 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
KHCADADO_02819 2.3e-93 yqhR S Conserved membrane protein YqhR
KHCADADO_02820 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KHCADADO_02821 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KHCADADO_02822 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHCADADO_02823 7.9e-37 yqhV S Protein of unknown function (DUF2619)
KHCADADO_02824 1.2e-171 spoIIIAA S stage III sporulation protein AA
KHCADADO_02825 2.9e-85 spoIIIAB S Stage III sporulation protein
KHCADADO_02826 7.6e-29 spoIIIAC S stage III sporulation protein AC
KHCADADO_02827 2.3e-58 spoIIIAD S Stage III sporulation protein AD
KHCADADO_02828 1.3e-197 spoIIIAE S stage III sporulation protein AE
KHCADADO_02829 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KHCADADO_02830 6.9e-103 spoIIIAG S stage III sporulation protein AG
KHCADADO_02831 9.9e-91 spoIIIAH S SpoIIIAH-like protein
KHCADADO_02832 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KHCADADO_02833 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KHCADADO_02834 2.1e-67 yqhY S protein conserved in bacteria
KHCADADO_02835 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHCADADO_02836 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHCADADO_02837 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHCADADO_02838 6.6e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHCADADO_02839 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KHCADADO_02840 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHCADADO_02841 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KHCADADO_02842 1.7e-78 argR K Regulates arginine biosynthesis genes
KHCADADO_02843 0.0 recN L May be involved in recombinational repair of damaged DNA
KHCADADO_02844 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
KHCADADO_02845 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KHCADADO_02847 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KHCADADO_02848 5.9e-27
KHCADADO_02849 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KHCADADO_02850 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KHCADADO_02851 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
KHCADADO_02852 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
KHCADADO_02853 1.8e-212 mmgC I acyl-CoA dehydrogenase
KHCADADO_02854 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KHCADADO_02855 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KHCADADO_02856 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KHCADADO_02857 4e-34 yqzF S Protein of unknown function (DUF2627)
KHCADADO_02858 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KHCADADO_02859 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KHCADADO_02860 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KHCADADO_02861 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
KHCADADO_02862 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KHCADADO_02863 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KHCADADO_02864 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KHCADADO_02865 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KHCADADO_02866 2.6e-152 bmrR K helix_turn_helix, mercury resistance
KHCADADO_02867 7.9e-208 norA EGP Major facilitator Superfamily
KHCADADO_02868 1.1e-89 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KHCADADO_02869 8.8e-63 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KHCADADO_02870 9.3e-77 yqiW S Belongs to the UPF0403 family
KHCADADO_02871 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
KHCADADO_02872 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
KHCADADO_02873 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KHCADADO_02874 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
KHCADADO_02875 1.4e-98 yqjB S protein conserved in bacteria
KHCADADO_02877 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KHCADADO_02878 1.4e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KHCADADO_02879 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KHCADADO_02880 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
KHCADADO_02881 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHCADADO_02882 4.5e-24 yqzJ
KHCADADO_02883 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHCADADO_02884 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHCADADO_02885 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHCADADO_02886 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KHCADADO_02887 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KHCADADO_02888 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KHCADADO_02889 0.0 rocB E arginine degradation protein
KHCADADO_02890 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHCADADO_02891 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KHCADADO_02892 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_02893 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KHCADADO_02894 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
KHCADADO_02895 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHCADADO_02897 5.2e-226 yqjV G Major Facilitator Superfamily
KHCADADO_02899 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHCADADO_02900 2.2e-49 S YolD-like protein
KHCADADO_02901 3.6e-87 yqjY K acetyltransferase
KHCADADO_02902 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KHCADADO_02903 4.7e-196 yqkA K GrpB protein
KHCADADO_02904 2.8e-54 yqkB S Belongs to the HesB IscA family
KHCADADO_02905 9.4e-39 yqkC S Protein of unknown function (DUF2552)
KHCADADO_02906 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KHCADADO_02907 4e-14 yqkE S Protein of unknown function (DUF3886)
KHCADADO_02908 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KHCADADO_02910 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KHCADADO_02911 4.6e-77 yqxK 3.6.4.12 L DNA helicase
KHCADADO_02912 1.6e-134 yqxK 3.6.4.12 L DNA helicase
KHCADADO_02913 4.5e-58 ansR K Transcriptional regulator
KHCADADO_02914 5.4e-63 ansA 3.5.1.1 EJ L-asparaginase
KHCADADO_02915 4.7e-114 ansA 3.5.1.1 EJ L-asparaginase
KHCADADO_02916 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KHCADADO_02917 3.1e-235 mleN C Na H antiporter
KHCADADO_02918 5.5e-242 mleA 1.1.1.38 C malic enzyme
KHCADADO_02919 2e-32 yqkK
KHCADADO_02920 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KHCADADO_02921 2.4e-80 fur P Belongs to the Fur family
KHCADADO_02922 3.7e-37 S Protein of unknown function (DUF4227)
KHCADADO_02923 2.6e-166 xerD L recombinase XerD
KHCADADO_02924 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KHCADADO_02925 9e-44 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KHCADADO_02926 2.7e-91 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KHCADADO_02927 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KHCADADO_02928 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KHCADADO_02929 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KHCADADO_02930 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHCADADO_02931 7.4e-112 spoVAA S Stage V sporulation protein AA
KHCADADO_02932 1e-67 spoVAB S Stage V sporulation protein AB
KHCADADO_02933 2.3e-78 spoVAC S stage V sporulation protein AC
KHCADADO_02934 9e-192 spoVAD I Stage V sporulation protein AD
KHCADADO_02935 2.2e-57 spoVAEB S stage V sporulation protein
KHCADADO_02936 1.4e-110 spoVAEA S stage V sporulation protein
KHCADADO_02937 1.4e-273 spoVAF EG Stage V sporulation protein AF
KHCADADO_02938 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KHCADADO_02939 1.3e-149 ypuA S Secreted protein
KHCADADO_02940 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHCADADO_02943 1.5e-17 S SNARE associated Golgi protein
KHCADADO_02944 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
KHCADADO_02945 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KHCADADO_02946 6e-55 ypuD
KHCADADO_02947 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHCADADO_02948 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
KHCADADO_02949 9.4e-211 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KHCADADO_02950 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KHCADADO_02951 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHCADADO_02952 4.1e-70 ypuF S Domain of unknown function (DUF309)
KHCADADO_02953 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHCADADO_02954 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHCADADO_02955 4e-98 ypuI S Protein of unknown function (DUF3907)
KHCADADO_02956 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KHCADADO_02957 3.5e-103 spmA S Spore maturation protein
KHCADADO_02958 1.9e-87 spmB S Spore maturation protein
KHCADADO_02959 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KHCADADO_02960 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KHCADADO_02961 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KHCADADO_02962 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KHCADADO_02963 9.9e-35 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_02964 5.4e-86 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_02965 0.0 resE 2.7.13.3 T Histidine kinase
KHCADADO_02966 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KHCADADO_02967 6.8e-201 rsiX
KHCADADO_02968 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KHCADADO_02969 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHCADADO_02970 2.8e-83 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHCADADO_02971 4.7e-41 fer C Ferredoxin
KHCADADO_02972 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
KHCADADO_02973 7e-267 recQ 3.6.4.12 L DNA helicase
KHCADADO_02974 2.2e-100 ypbD S metal-dependent membrane protease
KHCADADO_02975 7.4e-18 ypbE M Lysin motif
KHCADADO_02976 1.3e-48 ypbE M Lysin motif
KHCADADO_02977 2.8e-81 ypbF S Protein of unknown function (DUF2663)
KHCADADO_02978 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
KHCADADO_02979 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KHCADADO_02980 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KHCADADO_02981 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KHCADADO_02982 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
KHCADADO_02983 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KHCADADO_02984 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KHCADADO_02985 9.2e-113 ypfA M Flagellar protein YcgR
KHCADADO_02986 1.8e-23 S Family of unknown function (DUF5359)
KHCADADO_02987 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KHCADADO_02988 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
KHCADADO_02989 3.5e-152 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KHCADADO_02990 1e-07 S YpzI-like protein
KHCADADO_02991 1.3e-102 yphA
KHCADADO_02992 9.3e-27 seaA S YIEGIA protein
KHCADADO_02993 4.4e-112 seaA S YIEGIA protein
KHCADADO_02994 1.6e-28 ypzH
KHCADADO_02995 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KHCADADO_02996 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KHCADADO_02997 1.6e-18 yphE S Protein of unknown function (DUF2768)
KHCADADO_02998 5.4e-138 yphF
KHCADADO_02999 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KHCADADO_03000 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KHCADADO_03001 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
KHCADADO_03002 5.2e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KHCADADO_03003 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KHCADADO_03004 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KHCADADO_03005 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KHCADADO_03006 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KHCADADO_03007 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KHCADADO_03008 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHCADADO_03009 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KHCADADO_03010 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KHCADADO_03011 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHCADADO_03012 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KHCADADO_03013 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KHCADADO_03014 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KHCADADO_03015 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KHCADADO_03016 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KHCADADO_03017 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHCADADO_03018 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KHCADADO_03019 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KHCADADO_03020 4.1e-234 S COG0457 FOG TPR repeat
KHCADADO_03021 2.8e-99 ypiB S Belongs to the UPF0302 family
KHCADADO_03022 8.5e-78 ypiF S Protein of unknown function (DUF2487)
KHCADADO_03023 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KHCADADO_03024 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KHCADADO_03025 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KHCADADO_03026 4.4e-98 ypjA S membrane
KHCADADO_03027 6.1e-143 ypjB S sporulation protein
KHCADADO_03028 1.1e-113 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KHCADADO_03029 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KHCADADO_03030 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KHCADADO_03031 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KHCADADO_03032 2.4e-10 bshB1 S proteins, LmbE homologs
KHCADADO_03033 1.5e-109 bshB1 S proteins, LmbE homologs
KHCADADO_03034 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KHCADADO_03035 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KHCADADO_03036 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KHCADADO_03037 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KHCADADO_03038 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KHCADADO_03039 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KHCADADO_03040 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KHCADADO_03041 6.7e-23 ypmA S Protein of unknown function (DUF4264)
KHCADADO_03042 3.4e-80 ypmB S protein conserved in bacteria
KHCADADO_03043 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KHCADADO_03044 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KHCADADO_03045 5.7e-129 dnaD L DNA replication protein DnaD
KHCADADO_03046 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHCADADO_03047 4.7e-93 ypoC
KHCADADO_03048 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
KHCADADO_03049 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KHCADADO_03050 2.6e-188 yppC S Protein of unknown function (DUF2515)
KHCADADO_03053 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
KHCADADO_03055 1.2e-48 yppG S YppG-like protein
KHCADADO_03056 5.6e-69 hspX O Belongs to the small heat shock protein (HSP20) family
KHCADADO_03057 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KHCADADO_03058 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KHCADADO_03059 1.3e-237 yprB L RNase_H superfamily
KHCADADO_03060 2.3e-97 ypsA S Belongs to the UPF0398 family
KHCADADO_03061 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KHCADADO_03062 3.6e-65 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KHCADADO_03063 1.1e-141 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KHCADADO_03065 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KHCADADO_03066 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHCADADO_03067 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KHCADADO_03068 7.2e-134 ptxS K transcriptional
KHCADADO_03069 3.4e-35 ptxS K transcriptional
KHCADADO_03070 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KHCADADO_03071 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KHCADADO_03072 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KHCADADO_03073 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KHCADADO_03074 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KHCADADO_03075 1.6e-228 pbuX F xanthine
KHCADADO_03076 4.4e-208 bcsA Q Naringenin-chalcone synthase
KHCADADO_03077 5.1e-87 ypbQ S protein conserved in bacteria
KHCADADO_03078 0.0 ypbR S Dynamin family
KHCADADO_03079 1e-38 ypbS S Protein of unknown function (DUF2533)
KHCADADO_03080 2e-07
KHCADADO_03081 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
KHCADADO_03083 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
KHCADADO_03084 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KHCADADO_03085 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KHCADADO_03086 2.6e-27 ypeQ S Zinc-finger
KHCADADO_03087 8.1e-31 S Protein of unknown function (DUF2564)
KHCADADO_03088 3.8e-16 degR
KHCADADO_03089 7.9e-31 cspD K Cold-shock protein
KHCADADO_03090 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KHCADADO_03091 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHCADADO_03092 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KHCADADO_03093 3.1e-110 ypgQ S phosphohydrolase
KHCADADO_03094 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
KHCADADO_03095 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KHCADADO_03096 1.7e-75 yphP S Belongs to the UPF0403 family
KHCADADO_03097 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KHCADADO_03098 7.8e-114 ypjP S YpjP-like protein
KHCADADO_03099 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KHCADADO_03100 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHCADADO_03101 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHCADADO_03102 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KHCADADO_03103 4.2e-110 hlyIII S protein, Hemolysin III
KHCADADO_03104 1.6e-185 pspF K Transcriptional regulator
KHCADADO_03105 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KHCADADO_03106 3.1e-40 ypmP S Protein of unknown function (DUF2535)
KHCADADO_03107 6.3e-42 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KHCADADO_03108 2.1e-16 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KHCADADO_03109 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
KHCADADO_03110 2.1e-49 ypmS S protein conserved in bacteria
KHCADADO_03111 1.4e-26 ypmT S Uncharacterized ympT
KHCADADO_03112 2.6e-223 mepA V MATE efflux family protein
KHCADADO_03113 1.6e-70 ypoP K transcriptional
KHCADADO_03114 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHCADADO_03115 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KHCADADO_03116 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
KHCADADO_03117 2.7e-307 yokA L Recombinase
KHCADADO_03118 1.6e-107
KHCADADO_03119 8.9e-95
KHCADADO_03122 8.4e-156 aacC 2.3.1.81 V aminoglycoside
KHCADADO_03123 1.1e-83 S Bacterial PH domain
KHCADADO_03124 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
KHCADADO_03125 4.1e-203
KHCADADO_03126 6.7e-92 yokH G SMI1 / KNR4 family
KHCADADO_03127 1.2e-302 UW nuclease activity
KHCADADO_03128 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
KHCADADO_03129 3.2e-109 yokK S SMI1 / KNR4 family
KHCADADO_03130 2.8e-99 J Acetyltransferase (GNAT) domain
KHCADADO_03132 6.8e-09 S Domain of unknown function (DUF4879)
KHCADADO_03134 1.3e-37
KHCADADO_03135 5.8e-55 S YolD-like protein
KHCADADO_03136 1.9e-239 S impB/mucB/samB family C-terminal domain
KHCADADO_03139 3e-196 V Peptidase C39 family
KHCADADO_03140 4.2e-158 V Peptidase C39 family
KHCADADO_03141 1.2e-70 CO cell redox homeostasis
KHCADADO_03142 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KHCADADO_03143 5.5e-40 S SPP1 phage holin
KHCADADO_03144 4.4e-32 bhlA S BhlA holin family
KHCADADO_03145 1.6e-186 3.5.1.28 M Ami_2
KHCADADO_03147 6.5e-164
KHCADADO_03148 0.0 G Exopolysaccharide biosynthesis protein
KHCADADO_03149 6.4e-115
KHCADADO_03150 0.0 S Pfam Transposase IS66
KHCADADO_03151 6.2e-145 S Phage tail protein
KHCADADO_03152 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KHCADADO_03153 9.3e-116
KHCADADO_03156 7.8e-08
KHCADADO_03158 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KHCADADO_03159 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KHCADADO_03160 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KHCADADO_03161 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KHCADADO_03162 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHCADADO_03163 0.0 ydiF S ABC transporter
KHCADADO_03164 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KHCADADO_03165 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KHCADADO_03166 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KHCADADO_03167 2.8e-09 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHCADADO_03168 1.6e-109 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHCADADO_03169 2.9e-27 ydiK S Domain of unknown function (DUF4305)
KHCADADO_03170 7.9e-129 ydiL S CAAX protease self-immunity
KHCADADO_03171 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHCADADO_03172 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHCADADO_03174 6.4e-66 KL Phage plasmid primase P4 family
KHCADADO_03175 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
KHCADADO_03176 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KHCADADO_03178 1.2e-199 V AAA domain (dynein-related subfamily)
KHCADADO_03179 4.9e-257 J LlaJI restriction endonuclease
KHCADADO_03180 1.1e-08 ydjC S Abhydrolase domain containing 18
KHCADADO_03181 0.0 K NB-ARC domain
KHCADADO_03182 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
KHCADADO_03183 7.1e-256 gutA G MFS/sugar transport protein
KHCADADO_03184 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KHCADADO_03185 5.1e-114 pspA KT Phage shock protein A
KHCADADO_03186 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHCADADO_03187 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KHCADADO_03188 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
KHCADADO_03189 4.7e-196 S Ion transport 2 domain protein
KHCADADO_03190 2.7e-258 iolT EGP Major facilitator Superfamily
KHCADADO_03191 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KHCADADO_03192 4.5e-64 ydjM M Lytic transglycolase
KHCADADO_03193 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
KHCADADO_03194 1.4e-34 ydjO S Cold-inducible protein YdjO
KHCADADO_03195 9.5e-160 ydjP I Alpha/beta hydrolase family
KHCADADO_03196 2.4e-181 yeaA S Protein of unknown function (DUF4003)
KHCADADO_03197 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KHCADADO_03198 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KHCADADO_03199 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHCADADO_03200 1.6e-177 yeaC S COG0714 MoxR-like ATPases
KHCADADO_03201 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KHCADADO_03202 0.0 yebA E COG1305 Transglutaminase-like enzymes
KHCADADO_03203 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KHCADADO_03204 6e-212 pbuG S permease
KHCADADO_03205 1.1e-118 yebC M Membrane
KHCADADO_03207 4e-93 yebE S UPF0316 protein
KHCADADO_03208 8e-28 yebG S NETI protein
KHCADADO_03209 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHCADADO_03210 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHCADADO_03211 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHCADADO_03212 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KHCADADO_03213 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHCADADO_03214 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHCADADO_03215 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHCADADO_03216 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHCADADO_03217 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KHCADADO_03218 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHCADADO_03219 4.6e-272 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KHCADADO_03220 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
KHCADADO_03221 3.5e-73 K helix_turn_helix ASNC type
KHCADADO_03222 2.3e-232 yjeH E Amino acid permease
KHCADADO_03223 2.7e-27 S Protein of unknown function (DUF2892)
KHCADADO_03224 4.1e-18 yerA 3.5.4.2 F adenine deaminase
KHCADADO_03225 0.0 yerA 3.5.4.2 F adenine deaminase
KHCADADO_03226 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
KHCADADO_03227 4.8e-51 yerC S protein conserved in bacteria
KHCADADO_03228 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KHCADADO_03230 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KHCADADO_03231 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KHCADADO_03232 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHCADADO_03233 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
KHCADADO_03234 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
KHCADADO_03235 1.6e-123 sapB S MgtC SapB transporter
KHCADADO_03236 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHCADADO_03237 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHCADADO_03238 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KHCADADO_03239 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHCADADO_03240 4e-156 yerO K Transcriptional regulator
KHCADADO_03241 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHCADADO_03242 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KHCADADO_03243 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHCADADO_03244 3.2e-98 L Recombinase
KHCADADO_03245 3.2e-53 L Resolvase, N terminal domain
KHCADADO_03246 0.0 yeeA V Type II restriction enzyme, methylase subunits
KHCADADO_03247 0.0 yeeB L DEAD-like helicases superfamily
KHCADADO_03248 1.8e-212 pstS P T5orf172
KHCADADO_03250 6.2e-31 S Colicin immunity protein / pyocin immunity protein
KHCADADO_03251 5.5e-83 S Protein of unknown function, DUF600
KHCADADO_03252 0.0 L nucleic acid phosphodiester bond hydrolysis
KHCADADO_03253 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
KHCADADO_03254 5.5e-214 S Tetratricopeptide repeat
KHCADADO_03256 9.4e-127 yeeN K transcriptional regulatory protein
KHCADADO_03258 1.2e-103 dhaR3 K Transcriptional regulator
KHCADADO_03259 9.7e-82 yesE S SnoaL-like domain
KHCADADO_03260 2.2e-159 yesF GM NAD(P)H-binding
KHCADADO_03261 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
KHCADADO_03262 1.5e-45 cotJB S CotJB protein
KHCADADO_03263 5.2e-104 cotJC P Spore Coat
KHCADADO_03264 4.2e-103 yesJ K Acetyltransferase (GNAT) family
KHCADADO_03266 4.4e-104 yesL S Protein of unknown function, DUF624
KHCADADO_03267 0.0 yesM 2.7.13.3 T Histidine kinase
KHCADADO_03268 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
KHCADADO_03269 5e-248 yesO G Bacterial extracellular solute-binding protein
KHCADADO_03270 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
KHCADADO_03271 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
KHCADADO_03272 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
KHCADADO_03273 0.0 yesS K Transcriptional regulator
KHCADADO_03274 3.8e-133 E GDSL-like Lipase/Acylhydrolase
KHCADADO_03275 8.9e-132 yesU S Domain of unknown function (DUF1961)
KHCADADO_03276 1e-113 yesV S Protein of unknown function, DUF624
KHCADADO_03277 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KHCADADO_03278 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KHCADADO_03279 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
KHCADADO_03280 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
KHCADADO_03281 0.0 yetA
KHCADADO_03282 3.1e-56 yetA
KHCADADO_03283 1.5e-280 lplA G Bacterial extracellular solute-binding protein
KHCADADO_03284 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KHCADADO_03285 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
KHCADADO_03286 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KHCADADO_03287 6.1e-123 yetF S membrane
KHCADADO_03288 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KHCADADO_03289 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHCADADO_03290 2.2e-34
KHCADADO_03291 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KHCADADO_03292 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KHCADADO_03293 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
KHCADADO_03294 5.3e-105 yetJ S Belongs to the BI1 family
KHCADADO_03295 5.4e-159 yetK EG EamA-like transporter family
KHCADADO_03296 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
KHCADADO_03297 7.8e-213 yetM CH FAD binding domain
KHCADADO_03298 3.6e-199 yetN S Protein of unknown function (DUF3900)
KHCADADO_03299 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KHCADADO_03300 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KHCADADO_03301 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
KHCADADO_03302 1.9e-172 yfnG 4.2.1.45 M dehydratase
KHCADADO_03303 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
KHCADADO_03304 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KHCADADO_03305 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
KHCADADO_03306 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
KHCADADO_03307 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KHCADADO_03308 1.3e-241 yfnA E amino acid
KHCADADO_03309 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KHCADADO_03310 1.1e-113 yfmS NT chemotaxis protein
KHCADADO_03311 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KHCADADO_03312 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
KHCADADO_03313 2.8e-70 yfmP K transcriptional
KHCADADO_03314 1.5e-209 yfmO EGP Major facilitator Superfamily
KHCADADO_03315 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KHCADADO_03316 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KHCADADO_03317 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
KHCADADO_03318 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
KHCADADO_03319 1.5e-209 G Major Facilitator Superfamily
KHCADADO_03320 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
KHCADADO_03321 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
KHCADADO_03322 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_03323 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_03324 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KHCADADO_03325 2.9e-24 S Protein of unknown function (DUF3212)
KHCADADO_03326 7.6e-58 yflT S Heat induced stress protein YflT
KHCADADO_03327 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KHCADADO_03328 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
KHCADADO_03329 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KHCADADO_03330 8.9e-119 citT T response regulator
KHCADADO_03331 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
KHCADADO_03333 8.5e-227 citM C Citrate transporter
KHCADADO_03334 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KHCADADO_03335 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KHCADADO_03336 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KHCADADO_03337 9e-124 yflK S protein conserved in bacteria
KHCADADO_03338 4e-18 yflJ S Protein of unknown function (DUF2639)
KHCADADO_03340 2.4e-50 yflH S Protein of unknown function (DUF3243)
KHCADADO_03341 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
KHCADADO_03342 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KHCADADO_03343 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KHCADADO_03344 6e-67 yhdN S Domain of unknown function (DUF1992)
KHCADADO_03345 3.2e-256 agcS_1 E Sodium alanine symporter
KHCADADO_03346 1.6e-194 E Spore germination protein
KHCADADO_03348 5.1e-207 yfkR S spore germination
KHCADADO_03349 1.5e-283 yfkQ EG Spore germination protein
KHCADADO_03350 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHCADADO_03351 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KHCADADO_03352 1.8e-133 treR K transcriptional
KHCADADO_03353 1.6e-125 yfkO C nitroreductase
KHCADADO_03354 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KHCADADO_03355 8.7e-295 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KHCADADO_03356 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
KHCADADO_03357 6.8e-207 ydiM EGP Major facilitator Superfamily
KHCADADO_03358 2.1e-29 yfkK S Belongs to the UPF0435 family
KHCADADO_03359 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHCADADO_03360 8.4e-51 yfkI S gas vesicle protein
KHCADADO_03361 9.7e-144 yihY S Belongs to the UPF0761 family
KHCADADO_03362 5e-08
KHCADADO_03363 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KHCADADO_03364 6.1e-183 cax P COG0387 Ca2 H antiporter
KHCADADO_03365 1.2e-146 yfkD S YfkD-like protein
KHCADADO_03366 6e-149 yfkC M Mechanosensitive ion channel
KHCADADO_03367 5.4e-222 yfkA S YfkB-like domain
KHCADADO_03368 1.1e-26 yfjT
KHCADADO_03369 2.6e-154 pdaA G deacetylase
KHCADADO_03370 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KHCADADO_03371 1.7e-184 corA P Mediates influx of magnesium ions
KHCADADO_03372 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KHCADADO_03373 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHCADADO_03374 1.6e-39 S YfzA-like protein
KHCADADO_03375 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHCADADO_03376 3.9e-86 yfjM S Psort location Cytoplasmic, score
KHCADADO_03377 3e-29 yfjL
KHCADADO_03378 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KHCADADO_03379 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KHCADADO_03380 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KHCADADO_03381 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KHCADADO_03382 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KHCADADO_03383 1.2e-25 sspH S Belongs to the SspH family
KHCADADO_03384 4e-56 yfjF S UPF0060 membrane protein
KHCADADO_03385 1.3e-80 S Family of unknown function (DUF5381)
KHCADADO_03386 1.8e-101 yfjD S Family of unknown function (DUF5381)
KHCADADO_03387 4.1e-144 yfjC
KHCADADO_03388 9.2e-191 yfjB
KHCADADO_03389 1.1e-44 yfjA S Belongs to the WXG100 family
KHCADADO_03390 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KHCADADO_03391 2.1e-140 glvR K Helix-turn-helix domain, rpiR family
KHCADADO_03392 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHCADADO_03393 2.1e-310 yfiB3 V ABC transporter
KHCADADO_03394 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KHCADADO_03395 9.8e-65 mhqP S DoxX
KHCADADO_03396 5.7e-163 yfiE 1.13.11.2 S glyoxalase
KHCADADO_03397 1.5e-177 K AraC-like ligand binding domain
KHCADADO_03398 1.8e-262 iolT EGP Major facilitator Superfamily
KHCADADO_03399 8.4e-184 G Xylose isomerase
KHCADADO_03400 1.1e-233 S Oxidoreductase
KHCADADO_03401 1.1e-214 yxjM T Histidine kinase
KHCADADO_03402 3.2e-113 KT LuxR family transcriptional regulator
KHCADADO_03403 2.8e-164 V ABC transporter, ATP-binding protein
KHCADADO_03404 9.8e-214 V ABC-2 family transporter protein
KHCADADO_03405 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
KHCADADO_03406 8.3e-99 padR K transcriptional
KHCADADO_03407 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KHCADADO_03408 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KHCADADO_03409 2e-109 yfiR K Transcriptional regulator
KHCADADO_03410 5.1e-221 yfiS EGP Major facilitator Superfamily
KHCADADO_03411 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
KHCADADO_03412 8.7e-287 yfiU EGP Major facilitator Superfamily
KHCADADO_03413 3.1e-81 yfiV K transcriptional
KHCADADO_03414 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHCADADO_03415 6.2e-182 yfiY P ABC transporter substrate-binding protein
KHCADADO_03416 3.5e-169 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_03417 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_03418 1.8e-167 yfhB 5.3.3.17 S PhzF family
KHCADADO_03419 3.9e-107 yfhC C nitroreductase
KHCADADO_03420 2.1e-25 yfhD S YfhD-like protein
KHCADADO_03422 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
KHCADADO_03423 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
KHCADADO_03424 9.7e-52 yfhH S Protein of unknown function (DUF1811)
KHCADADO_03426 1.1e-209 yfhI EGP Major facilitator Superfamily
KHCADADO_03427 6.2e-20 sspK S reproduction
KHCADADO_03428 1.3e-44 yfhJ S WVELL protein
KHCADADO_03429 9.2e-92 batE T Bacterial SH3 domain homologues
KHCADADO_03430 3.5e-51 yfhL S SdpI/YhfL protein family
KHCADADO_03431 6.7e-172 yfhM S Alpha beta hydrolase
KHCADADO_03432 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KHCADADO_03433 0.0 yfhO S Bacterial membrane protein YfhO
KHCADADO_03434 5.5e-186 yfhP S membrane-bound metal-dependent
KHCADADO_03435 7.8e-212 mutY L A G-specific
KHCADADO_03436 6.9e-36 yfhS
KHCADADO_03437 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHCADADO_03438 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
KHCADADO_03439 4.9e-48 ygaB S YgaB-like protein
KHCADADO_03440 1.3e-104 ygaC J Belongs to the UPF0374 family
KHCADADO_03441 1.8e-301 ygaD V ABC transporter
KHCADADO_03442 8.7e-180 ygaE S Membrane
KHCADADO_03443 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KHCADADO_03444 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
KHCADADO_03445 4e-80 perR P Belongs to the Fur family
KHCADADO_03446 1.5e-56 ygzB S UPF0295 protein
KHCADADO_03447 6.7e-167 ygxA S Nucleotidyltransferase-like
KHCADADO_03449 2.1e-193 xerH A Belongs to the 'phage' integrase family
KHCADADO_03450 6.3e-70
KHCADADO_03451 2.5e-86
KHCADADO_03452 2.5e-10 xkdX
KHCADADO_03453 8.1e-07
KHCADADO_03454 3.7e-151
KHCADADO_03455 1.4e-13
KHCADADO_03456 1e-57
KHCADADO_03459 1.6e-90
KHCADADO_03460 8.1e-131
KHCADADO_03461 2.6e-91
KHCADADO_03462 1.4e-121
KHCADADO_03464 1.1e-68
KHCADADO_03465 5.1e-81
KHCADADO_03466 5.7e-186
KHCADADO_03467 1.6e-94
KHCADADO_03468 2.1e-266
KHCADADO_03469 6.3e-282
KHCADADO_03470 0.0 gp17a S Terminase-like family
KHCADADO_03471 1.8e-175
KHCADADO_03474 2.6e-230
KHCADADO_03476 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KHCADADO_03477 0.0
KHCADADO_03480 5.7e-55 bldD K domain, Protein
KHCADADO_03481 4e-17
KHCADADO_03483 5.9e-238
KHCADADO_03485 1.4e-256
KHCADADO_03486 4.6e-35 K Cro/C1-type HTH DNA-binding domain
KHCADADO_03487 3.8e-259
KHCADADO_03488 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
KHCADADO_03493 1.1e-96 S Super-infection exclusion protein B
KHCADADO_03494 1.2e-86
KHCADADO_03496 6.6e-106
KHCADADO_03501 2.4e-136 L Belongs to the 'phage' integrase family
KHCADADO_03502 4.2e-22 L Belongs to the 'phage' integrase family
KHCADADO_03503 6e-263 S DNA-sulfur modification-associated
KHCADADO_03504 2.1e-177
KHCADADO_03505 1.1e-33 K Transcriptional regulator
KHCADADO_03516 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
KHCADADO_03517 8.8e-12 S Protein of unknown function (DUF2815)
KHCADADO_03519 3e-78 yoqH M LysM domain
KHCADADO_03521 1.5e-97 S Protein of unknown function (DUF1273)
KHCADADO_03523 1e-44
KHCADADO_03530 2.3e-77
KHCADADO_03531 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
KHCADADO_03532 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
KHCADADO_03535 7.7e-149 S Pfam:DUF867
KHCADADO_03536 0.0 M Parallel beta-helix repeats
KHCADADO_03541 1.3e-170
KHCADADO_03542 7.6e-180 L AAA domain
KHCADADO_03543 1.4e-86
KHCADADO_03544 2.5e-217 3.6.4.12 J DnaB-like helicase C terminal domain
KHCADADO_03545 4.2e-46 3.6.4.12 J DnaB-like helicase C terminal domain
KHCADADO_03546 1.2e-224 L DNA primase activity
KHCADADO_03547 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KHCADADO_03548 0.0 2.7.7.7 L DNA polymerase
KHCADADO_03549 9.9e-115 DR0488 S protein conserved in bacteria
KHCADADO_03554 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
KHCADADO_03555 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KHCADADO_03557 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
KHCADADO_03574 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KHCADADO_03575 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHCADADO_03576 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHCADADO_03577 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHCADADO_03578 3.3e-97 L HNH endonuclease
KHCADADO_03579 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHCADADO_03580 6.1e-38 O Glutaredoxin
KHCADADO_03581 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KHCADADO_03582 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
KHCADADO_03587 2.5e-30 sspB S spore protein
KHCADADO_03588 1.9e-168 S Calcineurin-like phosphoesterase
KHCADADO_03596 1.4e-10 K Cro/C1-type HTH DNA-binding domain
KHCADADO_03597 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KHCADADO_03599 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
KHCADADO_03600 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KHCADADO_03601 3.3e-188 cgeB S Spore maturation protein
KHCADADO_03602 1.2e-65 cgeA
KHCADADO_03603 3.5e-38 cgeC
KHCADADO_03604 3.4e-233 cgeD M maturation of the outermost layer of the spore
KHCADADO_03605 2.9e-145 yiiD K acetyltransferase
KHCADADO_03608 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHCADADO_03609 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KHCADADO_03610 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KHCADADO_03611 8.2e-154 yodQ 3.5.1.16 E Acetylornithine deacetylase
KHCADADO_03612 7.1e-76 yodQ 3.5.1.16 E Acetylornithine deacetylase
KHCADADO_03613 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KHCADADO_03614 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
KHCADADO_03615 2.9e-47 yokU S YokU-like protein, putative antitoxin
KHCADADO_03616 1.4e-36 yozE S Belongs to the UPF0346 family
KHCADADO_03617 1.4e-124 yodN
KHCADADO_03619 2.8e-24 yozD S YozD-like protein
KHCADADO_03620 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
KHCADADO_03621 3.6e-54 yodL S YodL-like
KHCADADO_03622 5.3e-09
KHCADADO_03623 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KHCADADO_03624 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KHCADADO_03625 5.2e-24 yodI
KHCADADO_03626 1.7e-128 yodH Q Methyltransferase
KHCADADO_03627 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KHCADADO_03628 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHCADADO_03629 6.2e-28 S Protein of unknown function (DUF3311)
KHCADADO_03630 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
KHCADADO_03631 3.8e-113 mhqD S Carboxylesterase
KHCADADO_03632 4.8e-108 yodC C nitroreductase
KHCADADO_03633 1.7e-57 yodB K transcriptional
KHCADADO_03634 6.5e-45 yodA S tautomerase
KHCADADO_03635 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
KHCADADO_03636 3.4e-09
KHCADADO_03637 2.8e-42 yozR S COG0071 Molecular chaperone (small heat shock protein)
KHCADADO_03638 3.5e-163 rarD S -transporter
KHCADADO_03639 1.5e-43
KHCADADO_03640 2.2e-60 yojF S Protein of unknown function (DUF1806)
KHCADADO_03641 2.1e-125 yojG S deacetylase
KHCADADO_03642 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KHCADADO_03643 4.2e-245 norM V Multidrug efflux pump
KHCADADO_03645 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHCADADO_03646 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KHCADADO_03647 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KHCADADO_03648 1.4e-98 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHCADADO_03649 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
KHCADADO_03650 0.0 yojO P Von Willebrand factor
KHCADADO_03651 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KHCADADO_03652 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KHCADADO_03653 5.1e-168 yocS S -transporter
KHCADADO_03654 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KHCADADO_03655 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
KHCADADO_03656 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KHCADADO_03657 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KHCADADO_03658 2.7e-31 yozC
KHCADADO_03659 4.2e-56 yozO S Bacterial PH domain
KHCADADO_03660 1.9e-36 yocN
KHCADADO_03661 1.1e-40 yozN
KHCADADO_03662 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
KHCADADO_03663 6.1e-26
KHCADADO_03664 6.4e-54 yocL
KHCADADO_03665 3.3e-83 dksA T general stress protein
KHCADADO_03666 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHCADADO_03667 0.0 recQ 3.6.4.12 L DNA helicase
KHCADADO_03668 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
KHCADADO_03669 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KHCADADO_03670 3.2e-198 desK 2.7.13.3 T Histidine kinase
KHCADADO_03671 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KHCADADO_03672 6.9e-189 yocD 3.4.17.13 V peptidase S66
KHCADADO_03673 1.9e-94 yocC
KHCADADO_03674 2.2e-145
KHCADADO_03675 6.5e-76 yozB S membrane
KHCADADO_03676 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KHCADADO_03677 1e-51 czrA K transcriptional
KHCADADO_03678 2.5e-95 yobW
KHCADADO_03679 9e-178 yobV K WYL domain
KHCADADO_03680 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
KHCADADO_03681 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KHCADADO_03682 3e-99 yobS K Transcriptional regulator
KHCADADO_03683 2.5e-143 yobR 2.3.1.1 J FR47-like protein
KHCADADO_03684 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
KHCADADO_03685 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KHCADADO_03686 0.0 yobO M Pectate lyase superfamily protein
KHCADADO_03687 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
KHCADADO_03688 7.9e-105 yokH G SMI1 / KNR4 family
KHCADADO_03689 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KHCADADO_03690 3e-86 S SMI1-KNR4 cell-wall
KHCADADO_03691 2.7e-157 yobJ
KHCADADO_03692 0.0 K Psort location Cytoplasmic, score
KHCADADO_03693 1.2e-49
KHCADADO_03694 2.6e-38 S YolD-like protein
KHCADADO_03695 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHCADADO_03696 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHCADADO_03698 1.7e-207 S aspartate phosphatase
KHCADADO_03703 1.8e-178 yobF
KHCADADO_03704 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
KHCADADO_03705 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
KHCADADO_03707 5.7e-58 K Helix-turn-helix
KHCADADO_03708 1.4e-37 S TM2 domain
KHCADADO_03709 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
KHCADADO_03710 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
KHCADADO_03714 2.3e-170 bla 3.5.2.6 V beta-lactamase
KHCADADO_03715 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KHCADADO_03716 3.7e-78 yoaW
KHCADADO_03717 6e-160 yijE EG EamA-like transporter family
KHCADADO_03718 8.6e-159 yoaU K LysR substrate binding domain
KHCADADO_03719 1.1e-149 yoaT S Protein of unknown function (DUF817)
KHCADADO_03720 4.2e-37 yozG K Transcriptional regulator
KHCADADO_03721 4.3e-75 yoaS S Protein of unknown function (DUF2975)
KHCADADO_03722 2.4e-172 yoaR V vancomycin resistance protein
KHCADADO_03723 4.1e-89
KHCADADO_03725 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
KHCADADO_03726 1.5e-146 yoaP 3.1.3.18 K YoaP-like
KHCADADO_03728 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
KHCADADO_03730 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
KHCADADO_03731 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
KHCADADO_03732 2.3e-111 yoaK S Membrane
KHCADADO_03733 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
KHCADADO_03734 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KHCADADO_03735 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
KHCADADO_03736 1.5e-38 S Protein of unknown function (DUF4025)
KHCADADO_03737 7e-14
KHCADADO_03738 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
KHCADADO_03739 1.9e-33 yoaF
KHCADADO_03740 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KHCADADO_03741 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHCADADO_03742 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KHCADADO_03743 6.2e-235 yoaB EGP Major facilitator Superfamily
KHCADADO_03744 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KHCADADO_03745 3.1e-144 yoxB
KHCADADO_03746 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
KHCADADO_03747 1.7e-61 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_03748 7.1e-53 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KHCADADO_03749 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KHCADADO_03750 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHCADADO_03751 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHCADADO_03752 7.8e-155 gltC K Transcriptional regulator
KHCADADO_03753 3.8e-59 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KHCADADO_03754 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KHCADADO_03755 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KHCADADO_03756 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KHCADADO_03757 2.5e-158 gltR1 K Transcriptional regulator
KHCADADO_03758 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KHCADADO_03759 3e-34 yoeD G Helix-turn-helix domain
KHCADADO_03760 2.2e-96 L Integrase
KHCADADO_03762 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
KHCADADO_03763 2.3e-246 yoeA V MATE efflux family protein
KHCADADO_03764 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
KHCADADO_03765 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KHCADADO_03766 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KHCADADO_03768 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
KHCADADO_03769 2.2e-142 ybbA S Putative esterase
KHCADADO_03770 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_03771 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_03772 7.2e-167 feuA P Iron-uptake system-binding protein
KHCADADO_03773 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KHCADADO_03774 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
KHCADADO_03775 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KHCADADO_03776 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KHCADADO_03777 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHCADADO_03778 1.1e-150 ybbH K transcriptional
KHCADADO_03779 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KHCADADO_03780 6.4e-87 ybbJ J acetyltransferase
KHCADADO_03781 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KHCADADO_03787 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KHCADADO_03788 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KHCADADO_03789 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHCADADO_03790 3e-225 ybbR S protein conserved in bacteria
KHCADADO_03791 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHCADADO_03792 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHCADADO_03793 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KHCADADO_03794 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
KHCADADO_03795 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHCADADO_03796 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KHCADADO_03797 0.0 ybcC S Belongs to the UPF0753 family
KHCADADO_03798 3.7e-96 can 4.2.1.1 P carbonic anhydrase
KHCADADO_03799 3.9e-47
KHCADADO_03800 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
KHCADADO_03801 5.1e-50 ybzH K Helix-turn-helix domain
KHCADADO_03802 2e-203 ybcL EGP Major facilitator Superfamily
KHCADADO_03804 9.1e-239 J 4Fe-4S single cluster domain
KHCADADO_03805 4.5e-62 V CAAX protease self-immunity
KHCADADO_03806 1.8e-184 V CAAX protease self-immunity
KHCADADO_03807 1.9e-135 skfE V ABC transporter
KHCADADO_03808 4e-248 skfF S ABC transporter
KHCADADO_03809 7.8e-91 C HEAT repeats
KHCADADO_03810 9.6e-79 txn CO Thioredoxin-like
KHCADADO_03811 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KHCADADO_03812 1.5e-123 T Transcriptional regulatory protein, C terminal
KHCADADO_03813 1.8e-173 T His Kinase A (phospho-acceptor) domain
KHCADADO_03815 1.6e-140 KLT Protein tyrosine kinase
KHCADADO_03816 4.8e-154 ybdN
KHCADADO_03817 1.5e-217 ybdO S Domain of unknown function (DUF4885)
KHCADADO_03818 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KHCADADO_03819 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
KHCADADO_03820 4.9e-30 ybxH S Family of unknown function (DUF5370)
KHCADADO_03821 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
KHCADADO_03822 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KHCADADO_03823 4.9e-41 ybyB
KHCADADO_03824 1.8e-290 ybeC E amino acid
KHCADADO_03825 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KHCADADO_03826 7.3e-258 glpT G -transporter
KHCADADO_03827 2.9e-35 S Protein of unknown function (DUF2651)
KHCADADO_03828 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
KHCADADO_03829 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
KHCADADO_03832 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
KHCADADO_03833 8.8e-162 ybfH EG EamA-like transporter family
KHCADADO_03834 2.3e-145 msmR K AraC-like ligand binding domain
KHCADADO_03835 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KHCADADO_03836 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KHCADADO_03838 2.5e-169 S Alpha/beta hydrolase family
KHCADADO_03839 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHCADADO_03840 2.7e-85 ybfM S SNARE associated Golgi protein
KHCADADO_03841 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KHCADADO_03842 3.2e-46 ybfN
KHCADADO_03843 4.3e-258 S Erythromycin esterase
KHCADADO_03844 6.7e-167 ybfP K Transcriptional regulator
KHCADADO_03845 3.9e-192 yceA S Belongs to the UPF0176 family
KHCADADO_03846 1.6e-180 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHCADADO_03847 1.2e-25 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHCADADO_03848 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHCADADO_03849 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHCADADO_03850 4.9e-128 K UTRA
KHCADADO_03852 5.5e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KHCADADO_03853 6.7e-262 mmuP E amino acid
KHCADADO_03854 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KHCADADO_03855 2.3e-257 agcS E Sodium alanine symporter
KHCADADO_03856 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
KHCADADO_03857 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
KHCADADO_03858 9e-170 glnL T Regulator
KHCADADO_03859 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
KHCADADO_03860 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KHCADADO_03861 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
KHCADADO_03862 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KHCADADO_03863 1.5e-124 ycbG K FCD
KHCADADO_03864 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
KHCADADO_03865 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
KHCADADO_03866 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KHCADADO_03867 7.3e-172 eamA1 EG spore germination
KHCADADO_03868 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_03869 2.4e-170 T PhoQ Sensor
KHCADADO_03870 4.8e-168 ycbN V ABC transporter, ATP-binding protein
KHCADADO_03871 2.1e-115 S ABC-2 family transporter protein
KHCADADO_03872 8.2e-53 ycbP S Protein of unknown function (DUF2512)
KHCADADO_03873 1.3e-78 sleB 3.5.1.28 M Cell wall
KHCADADO_03874 6.6e-136 ycbR T vWA found in TerF C terminus
KHCADADO_03875 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KHCADADO_03876 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KHCADADO_03877 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHCADADO_03878 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHCADADO_03879 6.2e-210 ycbU E Selenocysteine lyase
KHCADADO_03880 5.8e-229 lmrB EGP the major facilitator superfamily
KHCADADO_03881 4.8e-102 yxaF K Transcriptional regulator
KHCADADO_03882 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KHCADADO_03883 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KHCADADO_03884 2e-59 S RDD family
KHCADADO_03885 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
KHCADADO_03886 2e-161 2.7.13.3 T GHKL domain
KHCADADO_03887 1.2e-126 lytR_2 T LytTr DNA-binding domain
KHCADADO_03888 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
KHCADADO_03889 4.5e-203 natB CP ABC-2 family transporter protein
KHCADADO_03890 1.6e-174 yccK C Aldo keto reductase
KHCADADO_03891 6.6e-177 ycdA S Domain of unknown function (DUF5105)
KHCADADO_03892 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KHCADADO_03893 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KHCADADO_03894 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
KHCADADO_03895 5.5e-174 S response regulator aspartate phosphatase
KHCADADO_03896 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
KHCADADO_03897 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KHCADADO_03898 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
KHCADADO_03899 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KHCADADO_03900 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KHCADADO_03901 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHCADADO_03902 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KHCADADO_03903 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
KHCADADO_03904 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
KHCADADO_03905 6.3e-137 terC P Protein of unknown function (DUF475)
KHCADADO_03906 0.0 yceG S Putative component of 'biosynthetic module'
KHCADADO_03907 2e-192 yceH P Belongs to the TelA family
KHCADADO_03908 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
KHCADADO_03909 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
KHCADADO_03910 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
KHCADADO_03911 5.1e-229 proV 3.6.3.32 E glycine betaine
KHCADADO_03912 1.7e-99 opuAB P glycine betaine
KHCADADO_03913 5.3e-164 opuAC E glycine betaine
KHCADADO_03914 1.2e-219 amhX S amidohydrolase
KHCADADO_03915 1e-257 ycgA S Membrane
KHCADADO_03916 1.1e-98 ycgB
KHCADADO_03917 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
KHCADADO_03918 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KHCADADO_03919 6.5e-293 lctP C L-lactate permease
KHCADADO_03920 6.2e-269 mdr EGP Major facilitator Superfamily
KHCADADO_03921 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
KHCADADO_03922 6.8e-113 ycgF E Lysine exporter protein LysE YggA
KHCADADO_03923 1.2e-151 yqcI S YqcI/YcgG family
KHCADADO_03924 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KHCADADO_03925 2.4e-112 ycgI S Domain of unknown function (DUF1989)
KHCADADO_03926 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KHCADADO_03927 2.5e-109 tmrB S AAA domain
KHCADADO_03928 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KHCADADO_03929 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
KHCADADO_03930 2.2e-179 oxyR3 K LysR substrate binding domain
KHCADADO_03931 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KHCADADO_03932 2.9e-145 ycgL S Predicted nucleotidyltransferase
KHCADADO_03933 5.1e-170 ycgM E Proline dehydrogenase
KHCADADO_03934 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KHCADADO_03935 1.4e-163 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHCADADO_03936 1.3e-76 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHCADADO_03937 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
KHCADADO_03938 2.6e-147 ycgQ S membrane
KHCADADO_03939 1.2e-139 ycgR S permeases
KHCADADO_03940 5.7e-163 I alpha/beta hydrolase fold
KHCADADO_03941 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KHCADADO_03942 5.2e-93 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KHCADADO_03943 2.3e-181 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KHCADADO_03944 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
KHCADADO_03945 2.7e-249 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHCADADO_03946 7.4e-198 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHCADADO_03947 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KHCADADO_03948 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KHCADADO_03949 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
KHCADADO_03950 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
KHCADADO_03951 5.5e-109 yciB M ErfK YbiS YcfS YnhG
KHCADADO_03952 1.4e-228 yciC S GTPases (G3E family)
KHCADADO_03953 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
KHCADADO_03954 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KHCADADO_03957 3.3e-77 yckC S membrane
KHCADADO_03958 3.5e-52 yckD S Protein of unknown function (DUF2680)
KHCADADO_03959 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHCADADO_03960 5.4e-35 nin S Competence protein J (ComJ)
KHCADADO_03961 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
KHCADADO_03962 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
KHCADADO_03963 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KHCADADO_03964 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KHCADADO_03965 1.3e-63 hxlR K transcriptional
KHCADADO_03966 7.2e-250 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_03967 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KHCADADO_03968 5.7e-140 srfAD Q thioesterase
KHCADADO_03969 4.2e-228 EGP Major Facilitator Superfamily
KHCADADO_03970 4.9e-91 S YcxB-like protein
KHCADADO_03971 7.4e-164 ycxC EG EamA-like transporter family
KHCADADO_03972 4.4e-255 ycxD K GntR family transcriptional regulator
KHCADADO_03973 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KHCADADO_03974 4.4e-115 yczE S membrane
KHCADADO_03975 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KHCADADO_03976 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
KHCADADO_03977 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KHCADADO_03978 4.9e-162 bsdA K LysR substrate binding domain
KHCADADO_03979 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KHCADADO_03980 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KHCADADO_03981 4e-39 bsdD 4.1.1.61 S response to toxic substance
KHCADADO_03982 1.1e-83 yclD
KHCADADO_03983 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
KHCADADO_03984 1.5e-267 dtpT E amino acid peptide transporter
KHCADADO_03985 2.9e-310 yclG M Pectate lyase superfamily protein
KHCADADO_03987 6.8e-282 gerKA EG Spore germination protein
KHCADADO_03988 1.3e-232 gerKC S spore germination
KHCADADO_03989 9.9e-200 gerKB F Spore germination protein
KHCADADO_03990 3.9e-122 yclH P ABC transporter
KHCADADO_03991 1.7e-204 yclI V ABC transporter (permease) YclI
KHCADADO_03992 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KHCADADO_03993 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KHCADADO_03994 5.2e-71 S aspartate phosphatase
KHCADADO_03998 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
KHCADADO_03999 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_04000 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHCADADO_04001 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KHCADADO_04002 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KHCADADO_04003 1.4e-251 ycnB EGP Major facilitator Superfamily
KHCADADO_04004 6.5e-154 ycnC K Transcriptional regulator
KHCADADO_04005 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
KHCADADO_04006 1.6e-45 ycnE S Monooxygenase
KHCADADO_04007 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KHCADADO_04008 1.7e-57 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KHCADADO_04009 8.3e-207 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KHCADADO_04010 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHCADADO_04011 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KHCADADO_04012 6.1e-149 glcU U Glucose uptake
KHCADADO_04013 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHCADADO_04014 1.3e-100 ycnI S protein conserved in bacteria
KHCADADO_04015 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
KHCADADO_04016 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KHCADADO_04017 7.3e-56
KHCADADO_04018 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KHCADADO_04019 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KHCADADO_04020 1e-17 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KHCADADO_04021 4.4e-166 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KHCADADO_04022 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KHCADADO_04023 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KHCADADO_04024 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KHCADADO_04025 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
KHCADADO_04026 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KHCADADO_04028 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KHCADADO_04029 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
KHCADADO_04030 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KHCADADO_04031 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
KHCADADO_04032 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KHCADADO_04033 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KHCADADO_04034 1.2e-132 kipR K Transcriptional regulator
KHCADADO_04035 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
KHCADADO_04037 1.4e-49 yczJ S biosynthesis
KHCADADO_04038 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KHCADADO_04039 2.8e-176 ydhF S Oxidoreductase
KHCADADO_04040 0.0 mtlR K transcriptional regulator, MtlR
KHCADADO_04041 1.4e-294 ydaB IQ acyl-CoA ligase
KHCADADO_04042 1.1e-99 ydaC Q Methyltransferase domain
KHCADADO_04043 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KHCADADO_04044 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KHCADADO_04045 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KHCADADO_04046 6.8e-77 ydaG 1.4.3.5 S general stress protein
KHCADADO_04047 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KHCADADO_04048 5.1e-47 ydzA EGP Major facilitator Superfamily
KHCADADO_04049 2.5e-74 lrpC K Transcriptional regulator
KHCADADO_04050 1.5e-40 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHCADADO_04051 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHCADADO_04052 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
KHCADADO_04053 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
KHCADADO_04054 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
KHCADADO_04055 4.5e-233 ydaM M Glycosyl transferase family group 2
KHCADADO_04056 9.2e-157 ydaN S Bacterial cellulose synthase subunit
KHCADADO_04057 1.3e-168 ydaN S Bacterial cellulose synthase subunit
KHCADADO_04058 0.0 ydaO E amino acid
KHCADADO_04059 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KHCADADO_04060 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHCADADO_04061 9.4e-40
KHCADADO_04062 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
KHCADADO_04064 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
KHCADADO_04065 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KHCADADO_04067 8.9e-59 ydbB G Cupin domain
KHCADADO_04068 2.8e-63 ydbC S Domain of unknown function (DUF4937
KHCADADO_04069 3.2e-155 ydbD P Catalase
KHCADADO_04070 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KHCADADO_04071 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KHCADADO_04072 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
KHCADADO_04073 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHCADADO_04074 4.4e-181 ydbI S AI-2E family transporter
KHCADADO_04075 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
KHCADADO_04076 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KHCADADO_04077 2.7e-52 ydbL
KHCADADO_04078 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KHCADADO_04079 1.1e-18 S Fur-regulated basic protein B
KHCADADO_04080 2.2e-07 S Fur-regulated basic protein A
KHCADADO_04081 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHCADADO_04082 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KHCADADO_04083 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KHCADADO_04084 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KHCADADO_04085 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KHCADADO_04086 2.1e-82 ydbS S Bacterial PH domain
KHCADADO_04087 2.2e-263 ydbT S Membrane
KHCADADO_04088 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KHCADADO_04089 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KHCADADO_04090 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KHCADADO_04091 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHCADADO_04092 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KHCADADO_04093 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KHCADADO_04094 1.3e-143 rsbR T Positive regulator of sigma-B
KHCADADO_04095 5.2e-57 rsbS T antagonist
KHCADADO_04096 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KHCADADO_04097 7.1e-189 rsbU 3.1.3.3 KT phosphatase
KHCADADO_04098 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
KHCADADO_04099 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KHCADADO_04100 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHCADADO_04101 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KHCADADO_04105 1.5e-82 ydcG S EVE domain
KHCADADO_04106 4.8e-30 ydcH K helix_turn_helix multiple antibiotic resistance protein
KHCADADO_04107 1.2e-32 ydcH K helix_turn_helix multiple antibiotic resistance protein
KHCADADO_04108 0.0 yhgF K COG2183 Transcriptional accessory protein
KHCADADO_04109 1.6e-84 ydcK S Belongs to the SprT family
KHCADADO_04117 1.9e-211 L Belongs to the 'phage' integrase family
KHCADADO_04118 1.3e-90 immA E IrrE N-terminal-like domain
KHCADADO_04119 4.3e-62 yvaO K Transcriptional
KHCADADO_04120 1.1e-16
KHCADADO_04121 8.3e-41
KHCADADO_04123 5.1e-63 S Bacterial protein of unknown function (DUF961)
KHCADADO_04124 1e-273 ydcQ D Ftsk spoiiie family protein
KHCADADO_04125 1.5e-205 nicK L Replication initiation factor
KHCADADO_04128 1.2e-32 yddA
KHCADADO_04129 1.5e-173 yddB S Conjugative transposon protein TcpC
KHCADADO_04130 3e-40 yddC
KHCADADO_04131 5.6e-38 yddD S TcpE family
KHCADADO_04132 0.0 yddE S AAA-like domain
KHCADADO_04133 2e-55 S Domain of unknown function (DUF1874)
KHCADADO_04134 0.0 yddG S maturation of SSU-rRNA
KHCADADO_04135 2.4e-189 yddH CBM50 M Lysozyme-like
KHCADADO_04136 8.7e-87 yddI
KHCADADO_04137 4.1e-65 S Domain of unknown function with cystatin-like fold (DUF4467)
KHCADADO_04138 9.5e-128 S TIR domain
KHCADADO_04139 3.1e-31 S response regulator aspartate phosphatase
KHCADADO_04140 8.1e-43 S response regulator aspartate phosphatase
KHCADADO_04142 3.4e-161
KHCADADO_04143 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHCADADO_04144 1.2e-41 lrpA K transcriptional
KHCADADO_04145 3.9e-78 lrpB K transcriptional
KHCADADO_04146 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
KHCADADO_04147 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
KHCADADO_04148 5e-227 ydeG EGP Major facilitator Superfamily
KHCADADO_04153 1.1e-16 ydhU P Manganese containing catalase
KHCADADO_04154 8.7e-78 ydhU P Catalase
KHCADADO_04155 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KHCADADO_04156 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
KHCADADO_04157 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KHCADADO_04158 3.9e-133 ydhQ K UTRA
KHCADADO_04159 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHCADADO_04160 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHCADADO_04161 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KHCADADO_04162 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KHCADADO_04163 4.6e-200 pbuE EGP Major facilitator Superfamily
KHCADADO_04164 1.7e-99 ydhK M Protein of unknown function (DUF1541)
KHCADADO_04165 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KHCADADO_04166 4.1e-86 K Acetyltransferase (GNAT) domain
KHCADADO_04168 4.6e-69 frataxin S Domain of unknown function (DU1801)
KHCADADO_04169 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KHCADADO_04170 6.5e-100
KHCADADO_04171 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KHCADADO_04172 3.3e-244 ydhD M Glycosyl hydrolase
KHCADADO_04173 6.5e-122 ydhC K FCD
KHCADADO_04174 1.2e-121 ydhB S membrane transporter protein
KHCADADO_04175 2.5e-209 tcaB EGP Major facilitator Superfamily
KHCADADO_04176 1.1e-69 ydgJ K Winged helix DNA-binding domain
KHCADADO_04177 6e-83 drgA C nitroreductase
KHCADADO_04178 0.0 ydgH S drug exporters of the RND superfamily
KHCADADO_04179 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
KHCADADO_04180 4.6e-91 dinB S DinB family
KHCADADO_04181 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KHCADADO_04182 4.2e-308 expZ S ABC transporter
KHCADADO_04183 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
KHCADADO_04184 1.9e-53 S DoxX-like family
KHCADADO_04185 1.5e-101 K Bacterial regulatory proteins, tetR family
KHCADADO_04186 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
KHCADADO_04187 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
KHCADADO_04188 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
KHCADADO_04189 5.2e-122 ydfS S Protein of unknown function (DUF421)
KHCADADO_04190 2.7e-112 ydfR S Protein of unknown function (DUF421)
KHCADADO_04192 6.3e-29
KHCADADO_04193 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
KHCADADO_04194 1.3e-57 traF CO Thioredoxin
KHCADADO_04195 8.8e-63 mhqP S DoxX
KHCADADO_04196 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
KHCADADO_04197 9.6e-112 ydfN C nitroreductase
KHCADADO_04198 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHCADADO_04199 3.6e-107 K Bacterial transcription activator, effector binding domain
KHCADADO_04200 1.1e-13 K Bacterial transcription activator, effector binding domain
KHCADADO_04201 5.9e-118 S Protein of unknown function (DUF554)
KHCADADO_04202 1.9e-177 S Alpha/beta hydrolase family
KHCADADO_04203 0.0 ydfJ S drug exporters of the RND superfamily
KHCADADO_04204 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KHCADADO_04205 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
KHCADADO_04207 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KHCADADO_04208 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
KHCADADO_04209 5.9e-117 ydfE S Flavin reductase like domain
KHCADADO_04210 3.6e-271 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KHCADADO_04211 1e-162 ydfC EG EamA-like transporter family
KHCADADO_04212 1.8e-141 ydfB J GNAT acetyltransferase
KHCADADO_04213 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KHCADADO_04214 1.3e-57 arsR K transcriptional
KHCADADO_04215 8.4e-105 ydeS K Transcriptional regulator
KHCADADO_04216 1.2e-195 ydeR EGP Major facilitator Superfamily
KHCADADO_04217 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
KHCADADO_04218 4.8e-69 ydeP K Transcriptional regulator
KHCADADO_04219 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KHCADADO_04220 1.1e-58 K HxlR-like helix-turn-helix
KHCADADO_04221 8.6e-107 ydeN S Serine hydrolase
KHCADADO_04222 4.2e-74 maoC I N-terminal half of MaoC dehydratase
KHCADADO_04223 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KHCADADO_04224 1.8e-153 ydeK EG -transporter
KHCADADO_04225 4e-116
KHCADADO_04226 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
KHCADADO_04227 2.9e-47 ydeH
KHCADADO_04228 3.4e-220 ydeG EGP Major facilitator superfamily
KHCADADO_04229 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KHCADADO_04230 2.5e-166 ydeE K AraC family transcriptional regulator
KHCADADO_04231 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KHCADADO_04232 1.1e-166 rhaS5 K AraC-like ligand binding domain
KHCADADO_04233 4.6e-35 ydzE EG spore germination
KHCADADO_04234 8.8e-63 carD K Transcription factor
KHCADADO_04235 8.7e-30 cspL K Cold shock
KHCADADO_04236 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KHCADADO_04238 2.9e-76 ctsR K Belongs to the CtsR family
KHCADADO_04239 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KHCADADO_04240 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KHCADADO_04241 0.0 clpC O Belongs to the ClpA ClpB family
KHCADADO_04242 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHCADADO_04243 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KHCADADO_04244 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KHCADADO_04245 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KHCADADO_04246 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KHCADADO_04247 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHCADADO_04248 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
KHCADADO_04249 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHCADADO_04250 6.2e-28 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHCADADO_04251 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHCADADO_04252 1.2e-88 yacP S RNA-binding protein containing a PIN domain
KHCADADO_04253 4.4e-115 sigH K Belongs to the sigma-70 factor family
KHCADADO_04254 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KHCADADO_04255 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
KHCADADO_04256 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHCADADO_04257 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KHCADADO_04258 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHCADADO_04259 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KHCADADO_04260 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
KHCADADO_04261 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHCADADO_04262 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHCADADO_04263 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KHCADADO_04264 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHCADADO_04265 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KHCADADO_04266 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHCADADO_04267 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHCADADO_04268 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KHCADADO_04269 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KHCADADO_04270 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHCADADO_04271 3e-105 rplD J Forms part of the polypeptide exit tunnel
KHCADADO_04272 2.6e-22 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KHCADADO_04273 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHCADADO_04274 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHCADADO_04275 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHCADADO_04276 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHCADADO_04277 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHCADADO_04278 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KHCADADO_04279 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHCADADO_04280 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHCADADO_04281 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHCADADO_04282 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHCADADO_04283 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHCADADO_04284 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHCADADO_04285 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHCADADO_04286 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHCADADO_04287 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHCADADO_04288 1.9e-23 rpmD J Ribosomal protein L30
KHCADADO_04289 1.8e-72 rplO J binds to the 23S rRNA
KHCADADO_04290 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KHCADADO_04291 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KHCADADO_04292 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
KHCADADO_04293 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHCADADO_04294 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KHCADADO_04295 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHCADADO_04296 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHCADADO_04297 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHCADADO_04298 3.6e-58 rplQ J Ribosomal protein L17
KHCADADO_04299 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHCADADO_04300 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHCADADO_04301 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHCADADO_04302 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KHCADADO_04303 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHCADADO_04304 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KHCADADO_04305 8.2e-145 ybaJ Q Methyltransferase domain
KHCADADO_04306 9.7e-66 ybaK S Protein of unknown function (DUF2521)
KHCADADO_04307 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KHCADADO_04308 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KHCADADO_04309 1.2e-84 gerD
KHCADADO_04310 1.5e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KHCADADO_04311 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
KHCADADO_04312 3.4e-31 csfB S Inhibitor of sigma-G Gin
KHCADADO_04313 1.4e-76 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KHCADADO_04314 4.5e-203 yaaN P Belongs to the TelA family
KHCADADO_04315 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KHCADADO_04316 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHCADADO_04317 2.2e-54 yaaQ S protein conserved in bacteria
KHCADADO_04318 1.5e-71 yaaR S protein conserved in bacteria
KHCADADO_04319 2.2e-182 holB 2.7.7.7 L DNA polymerase III
KHCADADO_04320 2.1e-146 yaaT S stage 0 sporulation protein
KHCADADO_04321 4.8e-31 yabA L Involved in initiation control of chromosome replication
KHCADADO_04322 7.6e-118 yabB 2.1.1.223 S Conserved hypothetical protein 95
KHCADADO_04323 1.5e-49 yazA L endonuclease containing a URI domain
KHCADADO_04324 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHCADADO_04325 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KHCADADO_04326 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHCADADO_04327 1.8e-144 tatD L hydrolase, TatD
KHCADADO_04328 4.3e-194 rpfB GH23 T protein conserved in bacteria
KHCADADO_04329 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHCADADO_04330 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KHCADADO_04331 3.3e-137 yabG S peptidase
KHCADADO_04332 7.8e-39 veg S protein conserved in bacteria
KHCADADO_04333 8.3e-27 sspF S DNA topological change
KHCADADO_04334 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHCADADO_04335 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KHCADADO_04336 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KHCADADO_04337 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KHCADADO_04338 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHCADADO_04339 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHCADADO_04340 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KHCADADO_04341 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KHCADADO_04342 2.4e-39 yabK S Peptide ABC transporter permease
KHCADADO_04343 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHCADADO_04344 1.5e-92 spoVT K stage V sporulation protein
KHCADADO_04345 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KHCADADO_04346 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KHCADADO_04347 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KHCADADO_04348 1.5e-49 yabP S Sporulation protein YabP
KHCADADO_04349 3.9e-108 yabQ S spore cortex biosynthesis protein
KHCADADO_04350 1.1e-44 divIC D Septum formation initiator
KHCADADO_04351 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KHCADADO_04354 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KHCADADO_04355 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
KHCADADO_04356 6.7e-187 KLT serine threonine protein kinase
KHCADADO_04357 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KHCADADO_04358 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KHCADADO_04359 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHCADADO_04360 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KHCADADO_04361 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHCADADO_04362 1.6e-160 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KHCADADO_04363 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KHCADADO_04364 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHCADADO_04365 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KHCADADO_04366 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KHCADADO_04367 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KHCADADO_04368 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHCADADO_04369 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KHCADADO_04370 4.1e-30 yazB K transcriptional
KHCADADO_04371 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHCADADO_04372 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KHCADADO_04373 2.7e-182 yaaC S YaaC-like Protein
KHCADADO_04374 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KHCADADO_04375 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KHCADADO_04376 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KHCADADO_04377 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KHCADADO_04378 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHCADADO_04379 1.3e-09
KHCADADO_04380 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KHCADADO_04381 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KHCADADO_04382 5.6e-215 yaaH M Glycoside Hydrolase Family
KHCADADO_04383 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
KHCADADO_04384 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KHCADADO_04385 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHCADADO_04386 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHCADADO_04387 2.7e-96 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHCADADO_04388 7.9e-32 yaaL S Protein of unknown function (DUF2508)
KHCADADO_04389 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
KHCADADO_04390 1.1e-130 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_04391 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_04392 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_04393 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_04394 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_04395 6.7e-270 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHCADADO_04396 1.2e-37 S Phage-related minor tail protein
KHCADADO_04397 4e-20 L Transglycosylase SLT domain
KHCADADO_04398 3.5e-24 L Transglycosylase SLT domain
KHCADADO_04399 3.2e-113 S Phage tail protein
KHCADADO_04400 4.9e-131 S peptidoglycan catabolic process
KHCADADO_04401 1.1e-23
KHCADADO_04402 5e-12 virB5 U conjugation
KHCADADO_04403 1.9e-18 L Phage integrase family
KHCADADO_04406 1.4e-31
KHCADADO_04409 2e-41 XK27_03185 S Phosphoribosyl-ATP pyrophosphohydrolase
KHCADADO_04410 1.4e-19
KHCADADO_04412 9.6e-20 S 3D domain
KHCADADO_04413 4.6e-09 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP dependent DNA ligase domain
KHCADADO_04414 2.3e-44 S DNA ligase (ATP) activity
KHCADADO_04416 1.8e-54 parC 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHCADADO_04417 4.9e-52 traC L Domain of unknown function (DUF1738)
KHCADADO_04421 6.5e-57 D Phage tail tape measure protein
KHCADADO_04424 9.2e-10 S Phage terminase, small subunit
KHCADADO_04429 2e-07
KHCADADO_04433 2.3e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
KHCADADO_04434 6.1e-21 xkdO M Phage tail tape measure protein, TP901 family
KHCADADO_04436 3.3e-28 S Phage tail tube protein
KHCADADO_04437 2.4e-49 S Immunity protein 70
KHCADADO_04438 1.8e-93 A Pre-toxin TG
KHCADADO_04439 7.8e-36 S AAA domain
KHCADADO_04440 6e-128
KHCADADO_04443 3.1e-21 2.7.4.8 F Guanylate kinase homologues.
KHCADADO_04445 3.1e-108 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
KHCADADO_04446 3.4e-39 S COG NOG14552 non supervised orthologous group
KHCADADO_04447 1.6e-12
KHCADADO_04448 9e-33 S DNA gyrase B subunit, carboxyl terminus
KHCADADO_04449 1e-55 S Phage portal protein
KHCADADO_04450 6.6e-60 S Ribonucleotide reductase, small chain
KHCADADO_04451 1.9e-08 fld C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
KHCADADO_04459 2e-08
KHCADADO_04465 5e-19 S Bacterial DNA polymerase III alpha subunit
KHCADADO_04467 1.8e-46 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHCADADO_04468 2.7e-43 S Bacterial DNA polymerase III alpha subunit
KHCADADO_04469 4.3e-24
KHCADADO_04470 1.3e-11 S response regulator aspartate phosphatase
KHCADADO_04472 1.3e-42 S Phage capsid family
KHCADADO_04476 6.4e-15 S DNA gyrase B subunit, carboxyl terminus
KHCADADO_04478 1.6e-11 2.7.7.7 L DNA polymerase
KHCADADO_04479 3.1e-49
KHCADADO_04480 3.3e-28 S DNA helicase activity
KHCADADO_04481 1.3e-18 sidC L Phage minor structural protein
KHCADADO_04482 4.4e-68 S Phage integrase family
KHCADADO_04483 1.9e-17 S DNA primase activity
KHCADADO_04484 3.9e-14 S DNA primase activity
KHCADADO_04487 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)