ORF_ID e_value Gene_name EC_number CAZy COGs Description
HKLHJAOF_00001 3.5e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKLHJAOF_00002 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKLHJAOF_00004 2.9e-31 yaaA S S4 domain protein YaaA
HKLHJAOF_00005 7.3e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKLHJAOF_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKLHJAOF_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKLHJAOF_00008 4.7e-08 ssb_2 L Single-strand binding protein family
HKLHJAOF_00010 2.6e-266 L Transposase DDE domain
HKLHJAOF_00012 2.6e-266 L Transposase DDE domain
HKLHJAOF_00013 2.7e-15
HKLHJAOF_00015 4.2e-74 ssb_2 L Single-strand binding protein family
HKLHJAOF_00016 2.7e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HKLHJAOF_00017 7.3e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKLHJAOF_00018 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKLHJAOF_00019 1.5e-91 yhbO 3.5.1.124 S DJ-1/PfpI family
HKLHJAOF_00020 9.8e-280 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
HKLHJAOF_00021 1e-182 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
HKLHJAOF_00022 2.1e-28
HKLHJAOF_00023 9.2e-108 S CAAX protease self-immunity
HKLHJAOF_00024 5.5e-84 V Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
HKLHJAOF_00025 2.6e-266 L Transposase DDE domain
HKLHJAOF_00027 1.1e-161 V ABC transporter
HKLHJAOF_00028 4.5e-189 amtB P Ammonium Transporter Family
HKLHJAOF_00029 8.6e-212 P Pyridine nucleotide-disulphide oxidoreductase
HKLHJAOF_00030 4e-125 usp 3.5.1.28 CBM50 D CHAP domain
HKLHJAOF_00031 0.0 ylbB V ABC transporter permease
HKLHJAOF_00032 6.3e-128 macB V ABC transporter, ATP-binding protein
HKLHJAOF_00033 3e-96 K transcriptional regulator
HKLHJAOF_00034 6.6e-153 supH G Sucrose-6F-phosphate phosphohydrolase
HKLHJAOF_00035 1.4e-45
HKLHJAOF_00036 2e-127 S membrane transporter protein
HKLHJAOF_00037 2.1e-103 S Protein of unknown function (DUF1211)
HKLHJAOF_00038 5e-113 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HKLHJAOF_00039 8.5e-54
HKLHJAOF_00041 1.5e-285 pipD E Dipeptidase
HKLHJAOF_00042 6.1e-106 S Membrane
HKLHJAOF_00043 2.1e-86
HKLHJAOF_00044 5.9e-53
HKLHJAOF_00046 6.1e-244 ybfG M peptidoglycan-binding domain-containing protein
HKLHJAOF_00047 2.4e-122 azlC E branched-chain amino acid
HKLHJAOF_00048 1.5e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HKLHJAOF_00049 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HKLHJAOF_00050 0.0 M Glycosyl hydrolase family 59
HKLHJAOF_00051 1.4e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HKLHJAOF_00052 4.6e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HKLHJAOF_00053 9.5e-280 uxaC 5.3.1.12 G glucuronate isomerase
HKLHJAOF_00054 3.3e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HKLHJAOF_00055 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
HKLHJAOF_00056 7.8e-267 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HKLHJAOF_00057 1.8e-229 G Major Facilitator
HKLHJAOF_00058 1.2e-126 kdgR K FCD domain
HKLHJAOF_00059 4.3e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HKLHJAOF_00060 0.0 M Glycosyl hydrolase family 59
HKLHJAOF_00061 1.6e-57
HKLHJAOF_00062 1e-64 S pyridoxamine 5-phosphate
HKLHJAOF_00063 1.3e-241 EGP Major facilitator Superfamily
HKLHJAOF_00064 2e-219 3.1.1.83 I Alpha beta hydrolase
HKLHJAOF_00065 8.4e-46 K Bacterial regulatory proteins, tetR family
HKLHJAOF_00066 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_00067 1.6e-46 K Bacterial regulatory proteins, tetR family
HKLHJAOF_00069 0.0 ydgH S MMPL family
HKLHJAOF_00070 1e-105 K Tetracycline repressor, C-terminal all-alpha domain
HKLHJAOF_00071 4.3e-122 S Sulfite exporter TauE/SafE
HKLHJAOF_00072 7.6e-244 3.5.4.28, 3.5.4.31 F Amidohydrolase family
HKLHJAOF_00073 1.9e-69 S An automated process has identified a potential problem with this gene model
HKLHJAOF_00074 1e-148 S Protein of unknown function (DUF3100)
HKLHJAOF_00076 1.9e-110 opuCD P Binding-protein-dependent transport system inner membrane component
HKLHJAOF_00077 1.6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKLHJAOF_00078 4.7e-106 opuCB E ABC transporter permease
HKLHJAOF_00079 1.2e-214 opuCA E ABC transporter, ATP-binding protein
HKLHJAOF_00080 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
HKLHJAOF_00081 5.6e-33 copZ P Heavy-metal-associated domain
HKLHJAOF_00082 3.6e-100 dps P Belongs to the Dps family
HKLHJAOF_00083 3.1e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HKLHJAOF_00085 6.3e-157 S CAAX protease self-immunity
HKLHJAOF_00086 2.2e-250 manY 2.7.1.191, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_00087 1.6e-79 frvA 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00088 0.0 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HKLHJAOF_00089 3.1e-139 K SIS domain
HKLHJAOF_00090 2.6e-274 bgl 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLHJAOF_00091 4.8e-157 bglK_1 2.7.1.2 GK ROK family
HKLHJAOF_00093 5.2e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKLHJAOF_00094 5.5e-228 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKLHJAOF_00095 3.2e-104 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HKLHJAOF_00096 3.3e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HKLHJAOF_00097 3.2e-181 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKLHJAOF_00099 2.1e-300 norB EGP Major Facilitator
HKLHJAOF_00100 8.8e-110 K Bacterial regulatory proteins, tetR family
HKLHJAOF_00101 4.3e-116
HKLHJAOF_00102 8e-158 S ABC-type transport system involved in multi-copper enzyme maturation permease component
HKLHJAOF_00103 1.3e-109
HKLHJAOF_00104 2.1e-99 V ATPases associated with a variety of cellular activities
HKLHJAOF_00105 1.7e-53
HKLHJAOF_00106 4.4e-106 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
HKLHJAOF_00107 7.7e-135 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKLHJAOF_00108 2.1e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKLHJAOF_00109 4.9e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKLHJAOF_00110 7.7e-73 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKLHJAOF_00111 5.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKLHJAOF_00112 4.4e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
HKLHJAOF_00113 5.6e-186 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKLHJAOF_00114 9.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKLHJAOF_00115 8e-61
HKLHJAOF_00116 5e-72 3.6.1.55 L NUDIX domain
HKLHJAOF_00117 1.1e-150 EG EamA-like transporter family
HKLHJAOF_00119 2.1e-51 L PFAM transposase, IS4 family protein
HKLHJAOF_00120 1.4e-105 L PFAM transposase, IS4 family protein
HKLHJAOF_00121 2.1e-61 K Tetracyclin repressor, C-terminal all-alpha domain
HKLHJAOF_00122 1.5e-55 V ABC-2 type transporter
HKLHJAOF_00123 6.8e-80 P ABC-2 family transporter protein
HKLHJAOF_00124 7.5e-100 V ABC transporter, ATP-binding protein
HKLHJAOF_00125 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HKLHJAOF_00126 5.1e-70 rplI J Binds to the 23S rRNA
HKLHJAOF_00127 1.7e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HKLHJAOF_00128 2.1e-221
HKLHJAOF_00129 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKLHJAOF_00130 1.5e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKLHJAOF_00131 6.6e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HKLHJAOF_00132 7.5e-155 K Helix-turn-helix domain, rpiR family
HKLHJAOF_00133 4.5e-106 K Transcriptional regulator C-terminal region
HKLHJAOF_00134 5.4e-127 V ABC transporter, ATP-binding protein
HKLHJAOF_00135 0.0 ylbB V ABC transporter permease
HKLHJAOF_00136 6.7e-206 4.1.1.52 S Amidohydrolase
HKLHJAOF_00137 4.9e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKLHJAOF_00138 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HKLHJAOF_00139 1.3e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHJAOF_00140 5.5e-204 yxaM EGP Major facilitator Superfamily
HKLHJAOF_00141 5.3e-153 K Helix-turn-helix XRE-family like proteins
HKLHJAOF_00142 1.6e-26 S Phospholipase_D-nuclease N-terminal
HKLHJAOF_00143 6.5e-120 yxlF V ABC transporter
HKLHJAOF_00144 1.2e-103 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKLHJAOF_00145 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HKLHJAOF_00146 9.7e-30
HKLHJAOF_00147 7.7e-51
HKLHJAOF_00148 3e-111 K Bacteriophage CI repressor helix-turn-helix domain
HKLHJAOF_00149 4.8e-182 yveB 2.7.4.29 I PAP2 superfamily
HKLHJAOF_00150 1.2e-207 mccF V LD-carboxypeptidase
HKLHJAOF_00151 7.3e-42
HKLHJAOF_00152 1.1e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HKLHJAOF_00153 2.1e-39
HKLHJAOF_00154 3.8e-111
HKLHJAOF_00155 7.8e-226 EGP Major facilitator Superfamily
HKLHJAOF_00156 5.7e-86
HKLHJAOF_00157 1.5e-200 T PhoQ Sensor
HKLHJAOF_00158 1.6e-120 K Transcriptional regulatory protein, C terminal
HKLHJAOF_00159 4.3e-91 ogt 2.1.1.63 L Methyltransferase
HKLHJAOF_00160 1.4e-189 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHJAOF_00161 2.9e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_00162 5.8e-52 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HKLHJAOF_00163 8e-85
HKLHJAOF_00164 1.6e-252 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHJAOF_00165 8e-287 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLHJAOF_00166 4.9e-131 K UTRA
HKLHJAOF_00167 5.6e-41
HKLHJAOF_00168 2.4e-57 ypaA S Protein of unknown function (DUF1304)
HKLHJAOF_00169 5.2e-54 S Protein of unknown function (DUF1516)
HKLHJAOF_00170 1.4e-254 pbuO S permease
HKLHJAOF_00171 9e-53 S DsrE/DsrF-like family
HKLHJAOF_00172 5.8e-188 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKLHJAOF_00173 1e-42
HKLHJAOF_00174 5.6e-106 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKLHJAOF_00175 0.0
HKLHJAOF_00177 1.1e-123 yqcC S WxL domain surface cell wall-binding
HKLHJAOF_00178 1.3e-183 ynjC S Cell surface protein
HKLHJAOF_00180 3.8e-271 L Mga helix-turn-helix domain
HKLHJAOF_00181 3.7e-150 yhaI S Protein of unknown function (DUF805)
HKLHJAOF_00182 7.4e-55
HKLHJAOF_00183 2.7e-252 rarA L recombination factor protein RarA
HKLHJAOF_00184 1.2e-216 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKLHJAOF_00185 3.2e-133 K DeoR C terminal sensor domain
HKLHJAOF_00186 2.1e-285 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HKLHJAOF_00187 6.4e-162 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HKLHJAOF_00188 7.3e-242 sgaT 2.7.1.194 S PTS system sugar-specific permease component
HKLHJAOF_00189 1.3e-159 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
HKLHJAOF_00190 1e-136 magIII L Base excision DNA repair protein, HhH-GPD family
HKLHJAOF_00191 5.7e-248 bmr3 EGP Major facilitator Superfamily
HKLHJAOF_00192 2.6e-266 L Transposase DDE domain
HKLHJAOF_00195 3e-89
HKLHJAOF_00197 6.6e-47 V ATPase activity
HKLHJAOF_00198 1.3e-16
HKLHJAOF_00200 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HKLHJAOF_00201 1.8e-303 oppA E ABC transporter, substratebinding protein
HKLHJAOF_00202 6.3e-76
HKLHJAOF_00203 8.6e-117
HKLHJAOF_00204 2e-116
HKLHJAOF_00205 2.5e-118 V ATPases associated with a variety of cellular activities
HKLHJAOF_00206 1.6e-74
HKLHJAOF_00207 2.5e-80 S NUDIX domain
HKLHJAOF_00208 3e-212 S nuclear-transcribed mRNA catabolic process, no-go decay
HKLHJAOF_00209 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
HKLHJAOF_00210 9.4e-261 nox 1.6.3.4 C NADH oxidase
HKLHJAOF_00211 1.7e-116
HKLHJAOF_00212 5.1e-210 S TPM domain
HKLHJAOF_00213 4e-129 yxaA S Sulfite exporter TauE/SafE
HKLHJAOF_00214 1e-55 ywjH S Protein of unknown function (DUF1634)
HKLHJAOF_00216 1.1e-64
HKLHJAOF_00217 2.1e-51
HKLHJAOF_00218 2.7e-82 fld C Flavodoxin
HKLHJAOF_00219 3.4e-36
HKLHJAOF_00220 6.7e-27
HKLHJAOF_00221 1.1e-170 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHJAOF_00222 9.1e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
HKLHJAOF_00223 6.4e-38 S Transglycosylase associated protein
HKLHJAOF_00224 5.8e-89 S Protein conserved in bacteria
HKLHJAOF_00225 2.5e-29
HKLHJAOF_00226 5.1e-61 asp23 S Asp23 family, cell envelope-related function
HKLHJAOF_00227 7.9e-65 asp2 S Asp23 family, cell envelope-related function
HKLHJAOF_00228 2.4e-129 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HKLHJAOF_00229 6e-115 S Protein of unknown function (DUF969)
HKLHJAOF_00230 5.2e-146 S Protein of unknown function (DUF979)
HKLHJAOF_00231 8.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKLHJAOF_00232 5.7e-104 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HKLHJAOF_00234 1e-127 cobQ S glutamine amidotransferase
HKLHJAOF_00235 3.7e-66
HKLHJAOF_00236 2.8e-134 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HKLHJAOF_00237 2.4e-142 noc K Belongs to the ParB family
HKLHJAOF_00238 7.4e-138 soj D Sporulation initiation inhibitor
HKLHJAOF_00239 2e-155 spo0J K Belongs to the ParB family
HKLHJAOF_00240 1.3e-30 yyzM S Bacterial protein of unknown function (DUF951)
HKLHJAOF_00241 2.8e-185 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKLHJAOF_00242 7.3e-141 XK27_01040 S Protein of unknown function (DUF1129)
HKLHJAOF_00243 5.1e-268 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKLHJAOF_00244 1.7e-117
HKLHJAOF_00245 2.5e-121 K response regulator
HKLHJAOF_00246 1.2e-219 hpk31 2.7.13.3 T Histidine kinase
HKLHJAOF_00247 5.3e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKLHJAOF_00248 1.2e-85 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKLHJAOF_00249 1e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKLHJAOF_00250 2.7e-140 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HKLHJAOF_00251 1.1e-163 yvgN C Aldo keto reductase
HKLHJAOF_00252 7.4e-141 iolR K DeoR C terminal sensor domain
HKLHJAOF_00253 1.9e-267 iolT EGP Major facilitator Superfamily
HKLHJAOF_00254 9.5e-275 iolA 1.2.1.18, 1.2.1.27 C Belongs to the aldehyde dehydrogenase family
HKLHJAOF_00255 6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HKLHJAOF_00256 5.4e-178 iolC 2.7.1.92 H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HKLHJAOF_00257 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HKLHJAOF_00258 7.1e-192 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HKLHJAOF_00259 1.8e-195 iolG2 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HKLHJAOF_00260 1.2e-174 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HKLHJAOF_00261 6.2e-157 iolJ 4.1.2.13, 4.1.2.29 G Fructose-bisphosphate aldolase class-II
HKLHJAOF_00262 1.7e-66 iolK S Tautomerase enzyme
HKLHJAOF_00263 1.7e-157 iolI 5.3.99.11 G Xylose isomerase-like TIM barrel
HKLHJAOF_00264 1.9e-169 iolH G Xylose isomerase-like TIM barrel
HKLHJAOF_00265 5.6e-147 gntR K rpiR family
HKLHJAOF_00266 9.6e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HKLHJAOF_00267 7.9e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HKLHJAOF_00268 5e-206 gntP EG Gluconate
HKLHJAOF_00269 4.9e-57
HKLHJAOF_00270 4.1e-130 fhuC 3.6.3.35 P ABC transporter
HKLHJAOF_00271 3e-134 znuB U ABC 3 transport family
HKLHJAOF_00272 6.4e-167 T Calcineurin-like phosphoesterase superfamily domain
HKLHJAOF_00273 1e-159 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HKLHJAOF_00274 0.0 pepF E oligoendopeptidase F
HKLHJAOF_00275 2e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HKLHJAOF_00276 2.3e-246 brnQ U Component of the transport system for branched-chain amino acids
HKLHJAOF_00277 4.5e-70 T Sh3 type 3 domain protein
HKLHJAOF_00278 2.2e-134 glcR K DeoR C terminal sensor domain
HKLHJAOF_00279 7.5e-146 M Glycosyltransferase like family 2
HKLHJAOF_00280 1.8e-133 XK27_06755 S Protein of unknown function (DUF975)
HKLHJAOF_00281 6.4e-52
HKLHJAOF_00282 2e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HKLHJAOF_00283 1.6e-174 draG O ADP-ribosylglycohydrolase
HKLHJAOF_00284 4.7e-293 S ABC transporter
HKLHJAOF_00285 8.5e-139 ksgA 2.1.1.182, 2.1.1.197, 2.5.1.134 J rRNA (adenine-N6,N6-)-dimethyltransferase activity
HKLHJAOF_00286 6.1e-35
HKLHJAOF_00287 1.5e-70 S COG NOG38524 non supervised orthologous group
HKLHJAOF_00288 6.8e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HKLHJAOF_00289 2.9e-43 trxC O Belongs to the thioredoxin family
HKLHJAOF_00290 2.8e-132 thrE S Putative threonine/serine exporter
HKLHJAOF_00291 3.5e-74 S Threonine/Serine exporter, ThrE
HKLHJAOF_00292 1.3e-213 livJ E Receptor family ligand binding region
HKLHJAOF_00293 6.7e-151 livH U Branched-chain amino acid transport system / permease component
HKLHJAOF_00294 1.7e-120 livM E Branched-chain amino acid transport system / permease component
HKLHJAOF_00295 4.7e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
HKLHJAOF_00296 1.8e-122 livF E ABC transporter
HKLHJAOF_00297 1.2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HKLHJAOF_00298 1.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HKLHJAOF_00299 2.3e-232 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHJAOF_00300 3.9e-116 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKLHJAOF_00301 4.4e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKLHJAOF_00302 2.2e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HKLHJAOF_00303 2.1e-144 p75 M NlpC P60 family protein
HKLHJAOF_00304 4.7e-260 nox 1.6.3.4 C NADH oxidase
HKLHJAOF_00305 2e-258 lacE-1 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HKLHJAOF_00306 7.8e-144 K CAT RNA binding domain
HKLHJAOF_00307 5.2e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HKLHJAOF_00308 1.2e-234 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HKLHJAOF_00309 4.8e-154 sepS16B
HKLHJAOF_00310 1.1e-116
HKLHJAOF_00311 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HKLHJAOF_00312 2.1e-238 malE G Bacterial extracellular solute-binding protein
HKLHJAOF_00313 1.7e-82
HKLHJAOF_00314 2.6e-296 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00315 3.1e-67 frvA 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00316 5.7e-240 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HKLHJAOF_00317 3.7e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKLHJAOF_00318 3.8e-129 XK27_08435 K UTRA
HKLHJAOF_00319 5.9e-219 agaS G SIS domain
HKLHJAOF_00320 4.1e-225 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKLHJAOF_00321 0.0 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
HKLHJAOF_00322 8.1e-82 manX_1 2.7.1.191 G PTS system sorbose subfamily IIB component
HKLHJAOF_00323 1.5e-140 XK27_08455 G PTS system sorbose-specific iic component
HKLHJAOF_00324 1e-145 manZ_1 G PTS system mannose/fructose/sorbose family IID component
HKLHJAOF_00325 3.5e-64 XK27_08465 2.7.1.191 G PTS system fructose IIA component
HKLHJAOF_00326 1.5e-294 2.4.1.52 GT4 M Glycosyl transferases group 1
HKLHJAOF_00327 2.2e-311 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HKLHJAOF_00328 4.9e-219 S Uncharacterized protein conserved in bacteria (DUF2325)
HKLHJAOF_00329 6.8e-231 4.4.1.8 E Aminotransferase, class I
HKLHJAOF_00330 5.1e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HKLHJAOF_00331 2.7e-252 2.7.1.207 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHJAOF_00332 1.8e-59 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_00333 1.9e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HKLHJAOF_00334 5.8e-194 ypdE E M42 glutamyl aminopeptidase
HKLHJAOF_00335 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00336 3.6e-235 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HKLHJAOF_00337 3.2e-292 E ABC transporter, substratebinding protein
HKLHJAOF_00338 2.9e-119 S Acetyltransferase (GNAT) family
HKLHJAOF_00340 1.2e-139 nisT V ABC transporter
HKLHJAOF_00341 1.2e-101 nisT V ABC transporter
HKLHJAOF_00342 5.8e-33
HKLHJAOF_00343 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_00344 1.1e-27
HKLHJAOF_00345 5.7e-95 S ABC-type cobalt transport system, permease component
HKLHJAOF_00346 1.3e-243 P ABC transporter
HKLHJAOF_00347 1.9e-110 P cobalt transport
HKLHJAOF_00348 1.7e-125 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKLHJAOF_00349 1.1e-81 thiW S Thiamine-precursor transporter protein (ThiW)
HKLHJAOF_00350 4.1e-150 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKLHJAOF_00351 1.6e-101 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKLHJAOF_00352 3.2e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKLHJAOF_00353 2.1e-271 E Amino acid permease
HKLHJAOF_00354 9.7e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HKLHJAOF_00355 8.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKLHJAOF_00356 1.3e-269 rbsA 3.6.3.17 G ABC transporter
HKLHJAOF_00357 1e-152 rbsC U Belongs to the binding-protein-dependent transport system permease family
HKLHJAOF_00358 4.3e-159 rbsB G Periplasmic binding protein domain
HKLHJAOF_00359 6.2e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKLHJAOF_00360 1.8e-42 K DNA-binding helix-turn-helix protein
HKLHJAOF_00361 2.5e-36
HKLHJAOF_00366 4.8e-143 S Protein of unknown function (DUF2785)
HKLHJAOF_00367 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
HKLHJAOF_00368 5.5e-52
HKLHJAOF_00369 7.1e-86 V AAA domain, putative AbiEii toxin, Type IV TA system
HKLHJAOF_00370 2.5e-70
HKLHJAOF_00371 4.5e-62
HKLHJAOF_00372 2.3e-94
HKLHJAOF_00373 1.3e-77 ydiC1 EGP Major facilitator Superfamily
HKLHJAOF_00374 1.9e-122 ydiC1 EGP Major facilitator Superfamily
HKLHJAOF_00375 2.3e-67 K helix_turn_helix multiple antibiotic resistance protein
HKLHJAOF_00376 3.9e-104
HKLHJAOF_00377 1e-28
HKLHJAOF_00378 9.6e-164 GKT transcriptional antiterminator
HKLHJAOF_00379 6e-46 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_00380 1.4e-205 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HKLHJAOF_00381 3.9e-48
HKLHJAOF_00382 3.2e-150 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HKLHJAOF_00383 3.8e-87 6.3.4.4 S Zeta toxin
HKLHJAOF_00384 2.1e-155 rihB 3.2.2.1 F Nucleoside
HKLHJAOF_00385 1.3e-212 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
HKLHJAOF_00386 1.4e-44 K Acetyltransferase (GNAT) family
HKLHJAOF_00387 6.3e-118 K helix_turn_helix gluconate operon transcriptional repressor
HKLHJAOF_00388 1.1e-88 4.1.2.13 G DeoC/LacD family aldolase
HKLHJAOF_00389 9.9e-39 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HKLHJAOF_00390 1.1e-180 2.7.1.53 G Belongs to the FGGY kinase family
HKLHJAOF_00391 1.4e-91 IQ KR domain
HKLHJAOF_00392 2.5e-125 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HKLHJAOF_00393 2e-156 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
HKLHJAOF_00394 3e-286 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00395 6.4e-154 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HKLHJAOF_00396 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphotransferase system
HKLHJAOF_00397 5.4e-239 sorE E Alcohol dehydrogenase GroES-like domain
HKLHJAOF_00398 2.2e-163 sorC K sugar-binding domain protein
HKLHJAOF_00399 4.1e-131 IQ NAD dependent epimerase/dehydratase family
HKLHJAOF_00400 3.6e-62 sorF 2.7.1.191, 2.7.1.206 G PTS system fructose IIA component
HKLHJAOF_00401 1.9e-78 sorB 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
HKLHJAOF_00402 3.6e-130 sorA U PTS system sorbose-specific iic component
HKLHJAOF_00403 1.2e-149 sorM G system, mannose fructose sorbose family IID component
HKLHJAOF_00404 4.9e-149 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HKLHJAOF_00405 1.4e-238 P transporter
HKLHJAOF_00406 1.2e-172 C FAD dependent oxidoreductase
HKLHJAOF_00407 4.9e-109 K Transcriptional regulator, LysR family
HKLHJAOF_00408 1.1e-158 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HKLHJAOF_00409 2.7e-97 S UPF0397 protein
HKLHJAOF_00410 0.0 3.6.3.24 P ATP-binding cassette cobalt transporter
HKLHJAOF_00411 1.8e-145 cbiQ P cobalt transport
HKLHJAOF_00412 1e-150 K Transcriptional regulator, LacI family
HKLHJAOF_00413 4.7e-244 G Major Facilitator
HKLHJAOF_00414 2.7e-47 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HKLHJAOF_00415 3e-235 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HKLHJAOF_00416 2.2e-250 frdC 1.3.5.4 C HI0933-like protein
HKLHJAOF_00417 2.9e-97 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
HKLHJAOF_00419 4.8e-188 pts36C G iic component
HKLHJAOF_00420 8.1e-09 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_00421 4.1e-30 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00422 5.9e-63 K DeoR C terminal sensor domain
HKLHJAOF_00423 1.3e-54 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKLHJAOF_00424 1.1e-57 gntR K rpiR family
HKLHJAOF_00425 3.3e-37 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00426 4e-168 S PTS system sugar-specific permease component
HKLHJAOF_00427 1.9e-25 2.7.1.194 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKLHJAOF_00428 2.2e-132 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
HKLHJAOF_00429 9.3e-67 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HKLHJAOF_00430 6.6e-219 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HKLHJAOF_00431 1.6e-210 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HKLHJAOF_00432 6.4e-39 glvR K Helix-turn-helix domain, rpiR family
HKLHJAOF_00434 2.8e-20 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HKLHJAOF_00435 3e-44 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKLHJAOF_00436 9.4e-52 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HKLHJAOF_00437 7.5e-91 K antiterminator
HKLHJAOF_00438 1.2e-234 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HKLHJAOF_00439 2e-232 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLHJAOF_00440 1.1e-230 manR K PRD domain
HKLHJAOF_00441 3.1e-30 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HKLHJAOF_00442 1.9e-167 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HKLHJAOF_00443 8e-66 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00444 5.7e-44 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_00445 1.2e-162 G Phosphotransferase System
HKLHJAOF_00446 6.3e-126 G Domain of unknown function (DUF4432)
HKLHJAOF_00447 2.4e-111 5.3.1.15 S Pfam:DUF1498
HKLHJAOF_00448 6.4e-199 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HKLHJAOF_00449 9.6e-188 2.7.1.199, 2.7.1.208 G pts system
HKLHJAOF_00450 2.5e-85 celG 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
HKLHJAOF_00451 7.8e-175 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HKLHJAOF_00452 1.2e-28 glvR K DNA-binding transcription factor activity
HKLHJAOF_00453 7.2e-61 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00454 9e-268 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_00455 2.2e-189 malY 4.4.1.8 E Aminotransferase class I and II
HKLHJAOF_00456 1.1e-218 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00457 9.6e-64 kdsD 5.3.1.13 M SIS domain
HKLHJAOF_00458 9.9e-45 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00459 3e-31 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_00460 4.3e-183 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HKLHJAOF_00461 7e-87 4.3.3.7 E Dihydrodipicolinate synthetase family
HKLHJAOF_00462 5.8e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HKLHJAOF_00463 9.6e-199 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00464 2.4e-18 hxlR K Transcriptional regulator, HxlR family
HKLHJAOF_00465 6.7e-58 pnb C nitroreductase
HKLHJAOF_00466 3.3e-119
HKLHJAOF_00467 8.7e-08 K DNA-templated transcription, initiation
HKLHJAOF_00468 1.3e-17 S YvrJ protein family
HKLHJAOF_00469 4.8e-145 yqfZ 3.2.1.17 M hydrolase, family 25
HKLHJAOF_00470 9.6e-86 ygfC K Bacterial regulatory proteins, tetR family
HKLHJAOF_00471 1.1e-184 hrtB V ABC transporter permease
HKLHJAOF_00472 3.7e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HKLHJAOF_00473 1.1e-261 npr 1.11.1.1 C NADH oxidase
HKLHJAOF_00474 3.7e-151 S hydrolase
HKLHJAOF_00475 7.6e-45 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HKLHJAOF_00476 4.6e-164 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HKLHJAOF_00477 3.3e-75 2.7.1.191 G PTS system sorbose subfamily IIB component
HKLHJAOF_00478 7.6e-125 G PTS system sorbose-specific iic component
HKLHJAOF_00479 2.3e-145 G PTS system mannose/fructose/sorbose family IID component
HKLHJAOF_00480 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_00481 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HKLHJAOF_00482 4e-61 2.7.1.191 G PTS system fructose IIA component
HKLHJAOF_00483 2.3e-309 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HKLHJAOF_00484 1.9e-136 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HKLHJAOF_00486 3.5e-22
HKLHJAOF_00489 1.9e-150 metQ_4 P Belongs to the nlpA lipoprotein family
HKLHJAOF_00490 3.5e-196 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HKLHJAOF_00491 3.1e-173
HKLHJAOF_00492 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HKLHJAOF_00493 9.4e-17
HKLHJAOF_00494 4e-104 K Bacterial regulatory proteins, tetR family
HKLHJAOF_00495 9.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
HKLHJAOF_00496 1e-102 dhaL 2.7.1.121 S Dak2
HKLHJAOF_00497 6.1e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HKLHJAOF_00498 1.2e-76 ohr O OsmC-like protein
HKLHJAOF_00499 5.6e-20
HKLHJAOF_00500 5.9e-13
HKLHJAOF_00502 1.5e-54
HKLHJAOF_00503 8.3e-252 L Exonuclease
HKLHJAOF_00504 6.5e-28 relB L RelB antitoxin
HKLHJAOF_00505 7e-29
HKLHJAOF_00506 1.2e-48 K Helix-turn-helix domain
HKLHJAOF_00507 4.8e-205 yceJ EGP Major facilitator Superfamily
HKLHJAOF_00508 5.2e-104 tag 3.2.2.20 L glycosylase
HKLHJAOF_00509 2.5e-77 L Resolvase, N-terminal
HKLHJAOF_00510 2.3e-215 tnpB L Putative transposase DNA-binding domain
HKLHJAOF_00512 9.1e-33
HKLHJAOF_00513 2.6e-266 L Transposase DDE domain
HKLHJAOF_00514 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HKLHJAOF_00515 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKLHJAOF_00516 6.1e-45
HKLHJAOF_00517 8.2e-153 V Beta-lactamase
HKLHJAOF_00518 7.3e-192 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HKLHJAOF_00519 6e-137 H Protein of unknown function (DUF1698)
HKLHJAOF_00520 1.7e-140 puuD S peptidase C26
HKLHJAOF_00521 3.5e-107 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HKLHJAOF_00522 1.3e-78 K Psort location Cytoplasmic, score
HKLHJAOF_00523 2.1e-257 6.3.1.2 E Glutamine synthetase N-terminal domain
HKLHJAOF_00524 3.6e-221 S Amidohydrolase
HKLHJAOF_00525 8e-227 E Amino acid permease
HKLHJAOF_00526 2.5e-74 K helix_turn_helix, mercury resistance
HKLHJAOF_00527 6.4e-162 morA2 S reductase
HKLHJAOF_00528 2.8e-193 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKLHJAOF_00529 4e-59 hxlR K Transcriptional regulator, HxlR family
HKLHJAOF_00530 1.5e-127 S membrane transporter protein
HKLHJAOF_00531 3.6e-197
HKLHJAOF_00532 4.6e-129 XK27_12140 V ATPases associated with a variety of cellular activities
HKLHJAOF_00533 5e-293 S Psort location CytoplasmicMembrane, score
HKLHJAOF_00534 2e-126 K Transcriptional regulatory protein, C terminal
HKLHJAOF_00535 5.1e-196 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HKLHJAOF_00536 1.9e-161 V ATPases associated with a variety of cellular activities
HKLHJAOF_00537 9.3e-198
HKLHJAOF_00538 1.4e-105
HKLHJAOF_00539 0.0 pepN 3.4.11.2 E aminopeptidase
HKLHJAOF_00540 2.4e-275 ycaM E amino acid
HKLHJAOF_00541 6.4e-238 G MFS/sugar transport protein
HKLHJAOF_00542 6e-72 S Protein of unknown function (DUF1440)
HKLHJAOF_00543 2.3e-161 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HKLHJAOF_00544 1e-173 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKLHJAOF_00546 7.2e-141
HKLHJAOF_00548 9.7e-211 metC 4.4.1.8 E cystathionine
HKLHJAOF_00549 2.8e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HKLHJAOF_00550 2.2e-120 tcyB E ABC transporter
HKLHJAOF_00551 2.2e-117
HKLHJAOF_00552 1.5e-253 brnQ U Component of the transport system for branched-chain amino acids
HKLHJAOF_00553 4.1e-76 S WxL domain surface cell wall-binding
HKLHJAOF_00554 1e-174 S Cell surface protein
HKLHJAOF_00555 1.2e-42
HKLHJAOF_00556 3.1e-247 XK27_00720 S Leucine-rich repeat (LRR) protein
HKLHJAOF_00558 5e-120 S WxL domain surface cell wall-binding
HKLHJAOF_00559 4.5e-56
HKLHJAOF_00560 3e-114 N WxL domain surface cell wall-binding
HKLHJAOF_00561 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HKLHJAOF_00562 1.6e-166 yicL EG EamA-like transporter family
HKLHJAOF_00563 4.4e-300
HKLHJAOF_00564 8.5e-145 CcmA5 V ABC transporter
HKLHJAOF_00565 6.2e-78 S ECF-type riboflavin transporter, S component
HKLHJAOF_00566 6.7e-145 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HKLHJAOF_00567 5.2e-164 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
HKLHJAOF_00568 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKLHJAOF_00569 0.0 XK27_09600 V ABC transporter, ATP-binding protein
HKLHJAOF_00570 0.0 V ABC transporter
HKLHJAOF_00571 4.7e-219 oxlT P Major Facilitator Superfamily
HKLHJAOF_00572 3.2e-127 treR K UTRA
HKLHJAOF_00573 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HKLHJAOF_00574 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKLHJAOF_00575 6.9e-213 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HKLHJAOF_00576 1.2e-269 yfnA E Amino Acid
HKLHJAOF_00577 4.3e-172 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HKLHJAOF_00578 9.6e-250 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKLHJAOF_00579 4.6e-31 K 'Cold-shock' DNA-binding domain
HKLHJAOF_00580 1.3e-70
HKLHJAOF_00581 3.5e-76 O OsmC-like protein
HKLHJAOF_00582 1.5e-283 lsa S ABC transporter
HKLHJAOF_00583 3.9e-113 ylbE GM NAD(P)H-binding
HKLHJAOF_00584 3.7e-160 yeaE S Aldo/keto reductase family
HKLHJAOF_00585 7.1e-256 yifK E Amino acid permease
HKLHJAOF_00586 2.8e-283 S Protein of unknown function (DUF3800)
HKLHJAOF_00587 0.0 yjcE P Sodium proton antiporter
HKLHJAOF_00588 3.2e-55 S Protein of unknown function (DUF3021)
HKLHJAOF_00589 2.8e-68 K LytTr DNA-binding domain
HKLHJAOF_00590 6.4e-146 cylB V ABC-2 type transporter
HKLHJAOF_00591 1.7e-157 cylA V ABC transporter
HKLHJAOF_00592 2.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
HKLHJAOF_00593 6.9e-113 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HKLHJAOF_00594 1.2e-52 ybjQ S Belongs to the UPF0145 family
HKLHJAOF_00595 1.1e-92 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
HKLHJAOF_00596 2e-158 3.5.1.10 C nadph quinone reductase
HKLHJAOF_00597 2.2e-243 amt P ammonium transporter
HKLHJAOF_00598 4e-178 yfeX P Peroxidase
HKLHJAOF_00599 1.5e-118 yhiD S MgtC family
HKLHJAOF_00600 9.3e-147 F DNA RNA non-specific endonuclease
HKLHJAOF_00602 1.2e-10
HKLHJAOF_00603 2.3e-311 ybiT S ABC transporter, ATP-binding protein
HKLHJAOF_00604 2.7e-273 mutS L ATPase domain of DNA mismatch repair MUTS family
HKLHJAOF_00605 2e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
HKLHJAOF_00606 3.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HKLHJAOF_00607 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HKLHJAOF_00608 1.1e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKLHJAOF_00609 3.3e-135 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
HKLHJAOF_00610 6.5e-138 lacT K PRD domain
HKLHJAOF_00611 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HKLHJAOF_00612 6.2e-247 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HKLHJAOF_00613 1.9e-50 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HKLHJAOF_00615 6.2e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKLHJAOF_00616 2.1e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKLHJAOF_00617 6.5e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HKLHJAOF_00618 1.5e-162 K Transcriptional regulator
HKLHJAOF_00619 1.4e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HKLHJAOF_00621 3.3e-70 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_00622 1.7e-48 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_00623 2.3e-249 gatC G PTS system sugar-specific permease component
HKLHJAOF_00625 1.7e-28
HKLHJAOF_00626 8e-188 V Beta-lactamase
HKLHJAOF_00627 1.3e-125 S Domain of unknown function (DUF4867)
HKLHJAOF_00628 3.2e-175 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HKLHJAOF_00629 5.6e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HKLHJAOF_00630 9.9e-94 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HKLHJAOF_00631 6.1e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HKLHJAOF_00632 1.9e-141 lacR K DeoR C terminal sensor domain
HKLHJAOF_00633 3.6e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HKLHJAOF_00634 4.3e-211 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKLHJAOF_00635 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HKLHJAOF_00636 6e-09
HKLHJAOF_00637 3.1e-86 hsp1 O Belongs to the small heat shock protein (HSP20) family
HKLHJAOF_00638 7.5e-209 mutY L A G-specific adenine glycosylase
HKLHJAOF_00639 7.4e-149 cytC6 I alpha/beta hydrolase fold
HKLHJAOF_00640 5.9e-121 yrkL S Flavodoxin-like fold
HKLHJAOF_00642 1.7e-88 S Short repeat of unknown function (DUF308)
HKLHJAOF_00643 1.9e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKLHJAOF_00644 2.7e-199
HKLHJAOF_00645 1.5e-06
HKLHJAOF_00646 5.2e-116 ywnB S NmrA-like family
HKLHJAOF_00647 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_00648 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
HKLHJAOF_00650 8e-166 XK27_00670 S ABC transporter substrate binding protein
HKLHJAOF_00651 1.2e-164 XK27_00670 S ABC transporter
HKLHJAOF_00652 7.6e-156 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HKLHJAOF_00653 5.2e-142 cmpC S ABC transporter, ATP-binding protein
HKLHJAOF_00654 4.9e-171 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
HKLHJAOF_00655 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HKLHJAOF_00656 9.6e-183 ykcC GT2 M Glycosyl transferase family 2
HKLHJAOF_00657 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HKLHJAOF_00658 6.4e-72 S GtrA-like protein
HKLHJAOF_00659 1.7e-09
HKLHJAOF_00660 2.8e-08
HKLHJAOF_00661 2.2e-128 K cheY-homologous receiver domain
HKLHJAOF_00662 3.9e-240 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HKLHJAOF_00663 1.2e-67 yqkB S Belongs to the HesB IscA family
HKLHJAOF_00664 1.9e-121 drgA C Nitroreductase family
HKLHJAOF_00665 2.9e-204 lctO C IMP dehydrogenase / GMP reductase domain
HKLHJAOF_00668 6.4e-07 Z012_04635 K Helix-turn-helix domain
HKLHJAOF_00670 4.2e-06 mutR K Helix-turn-helix
HKLHJAOF_00672 1.4e-181 K sequence-specific DNA binding
HKLHJAOF_00673 3.1e-56 K Transcriptional regulator PadR-like family
HKLHJAOF_00674 4e-42 ygbF S Sugar efflux transporter for intercellular exchange
HKLHJAOF_00675 2.5e-49
HKLHJAOF_00676 1.1e-184 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKLHJAOF_00677 3.4e-56
HKLHJAOF_00678 3.4e-80
HKLHJAOF_00679 2.3e-207 yubA S AI-2E family transporter
HKLHJAOF_00680 7.4e-26
HKLHJAOF_00681 3e-97 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKLHJAOF_00682 2.1e-74
HKLHJAOF_00683 2.9e-168 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HKLHJAOF_00684 1.5e-104 ywrF S Flavin reductase like domain
HKLHJAOF_00685 6.7e-96
HKLHJAOF_00686 1.4e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKLHJAOF_00687 3.3e-61 yeaO S Protein of unknown function, DUF488
HKLHJAOF_00688 6.6e-173 corA P CorA-like Mg2+ transporter protein
HKLHJAOF_00689 2.1e-160 mleR K LysR family
HKLHJAOF_00690 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HKLHJAOF_00691 1.1e-170 mleP S Sodium Bile acid symporter family
HKLHJAOF_00692 5.9e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKLHJAOF_00693 3.1e-95
HKLHJAOF_00694 6e-169 K sequence-specific DNA binding
HKLHJAOF_00695 1.7e-282 V ABC transporter transmembrane region
HKLHJAOF_00696 0.0 pepF E Oligopeptidase F
HKLHJAOF_00697 5e-78 ndk 2.7.4.6 F Belongs to the NDK family
HKLHJAOF_00698 1.3e-54
HKLHJAOF_00699 0.0 yfgQ P E1-E2 ATPase
HKLHJAOF_00700 8.8e-178 3.4.11.5 I Releases the N-terminal proline from various substrates
HKLHJAOF_00701 1.8e-59
HKLHJAOF_00702 4.6e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKLHJAOF_00703 3.6e-197 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKLHJAOF_00704 1.6e-120 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
HKLHJAOF_00705 1.5e-77 K Transcriptional regulator
HKLHJAOF_00706 3.6e-179 D Alpha beta
HKLHJAOF_00707 1.3e-84 nrdI F Belongs to the NrdI family
HKLHJAOF_00708 1.5e-157 dkgB S reductase
HKLHJAOF_00709 1.1e-120
HKLHJAOF_00710 3.4e-160 S Alpha beta hydrolase
HKLHJAOF_00711 2.3e-116 yviA S Protein of unknown function (DUF421)
HKLHJAOF_00712 3.5e-74 S Protein of unknown function (DUF3290)
HKLHJAOF_00713 6.7e-220 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HKLHJAOF_00714 1.6e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKLHJAOF_00715 4.6e-103 yjbF S SNARE associated Golgi protein
HKLHJAOF_00716 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKLHJAOF_00717 6.2e-196 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKLHJAOF_00718 9.5e-208 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKLHJAOF_00719 3.9e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKLHJAOF_00720 3.9e-48 yajC U Preprotein translocase
HKLHJAOF_00721 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HKLHJAOF_00722 3.9e-116 sirR K Helix-turn-helix diphteria tox regulatory element
HKLHJAOF_00723 1.1e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKLHJAOF_00724 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLHJAOF_00725 5.2e-240 ytoI K DRTGG domain
HKLHJAOF_00726 4.8e-179 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HKLHJAOF_00727 5.6e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKLHJAOF_00728 1.4e-170
HKLHJAOF_00730 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKLHJAOF_00731 2.3e-201
HKLHJAOF_00732 1.2e-42 yrzL S Belongs to the UPF0297 family
HKLHJAOF_00733 2.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKLHJAOF_00734 2.3e-53 yrzB S Belongs to the UPF0473 family
HKLHJAOF_00735 2e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKLHJAOF_00736 8.6e-93 cvpA S Colicin V production protein
HKLHJAOF_00737 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKLHJAOF_00738 6.6e-53 trxA O Belongs to the thioredoxin family
HKLHJAOF_00739 9.4e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHJAOF_00740 1.8e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
HKLHJAOF_00741 4e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHJAOF_00742 1.2e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKLHJAOF_00743 1.1e-83 yslB S Protein of unknown function (DUF2507)
HKLHJAOF_00744 2.6e-277 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKLHJAOF_00745 2.4e-95 S Phosphoesterase
HKLHJAOF_00746 8.9e-133 gla U Major intrinsic protein
HKLHJAOF_00747 8.7e-84 ykuL S CBS domain
HKLHJAOF_00748 4.2e-156 XK27_00890 S Domain of unknown function (DUF368)
HKLHJAOF_00749 1.2e-155 ykuT M mechanosensitive ion channel
HKLHJAOF_00752 4.9e-74 ytxH S YtxH-like protein
HKLHJAOF_00753 1.9e-92 niaR S 3H domain
HKLHJAOF_00754 7.5e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HKLHJAOF_00755 2.3e-179 ccpA K catabolite control protein A
HKLHJAOF_00756 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HKLHJAOF_00757 1.9e-07
HKLHJAOF_00758 5.2e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HKLHJAOF_00759 2.6e-135 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKLHJAOF_00760 4.2e-272 pepV 3.5.1.18 E dipeptidase PepV
HKLHJAOF_00761 6.8e-256 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HKLHJAOF_00762 2.1e-54
HKLHJAOF_00763 6.4e-188 yibE S overlaps another CDS with the same product name
HKLHJAOF_00764 5.9e-116 yibF S overlaps another CDS with the same product name
HKLHJAOF_00765 1.8e-115 S Calcineurin-like phosphoesterase
HKLHJAOF_00766 2.2e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKLHJAOF_00767 8.8e-110 yutD S Protein of unknown function (DUF1027)
HKLHJAOF_00768 1.7e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKLHJAOF_00769 5.6e-115 S Protein of unknown function (DUF1461)
HKLHJAOF_00770 2.3e-116 dedA S SNARE-like domain protein
HKLHJAOF_00771 1.5e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HKLHJAOF_00772 7.9e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HKLHJAOF_00773 3.8e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKLHJAOF_00774 1.3e-63 yugI 5.3.1.9 J general stress protein
HKLHJAOF_00775 6.1e-35
HKLHJAOF_00776 2.4e-71 S COG NOG38524 non supervised orthologous group
HKLHJAOF_00777 6.8e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HKLHJAOF_00803 5.1e-72 sigH K Sigma-70 region 2
HKLHJAOF_00804 1.1e-297 ybeC E amino acid
HKLHJAOF_00805 4.5e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HKLHJAOF_00806 2.6e-194 cpoA GT4 M Glycosyltransferase, group 1 family protein
HKLHJAOF_00807 2.9e-166 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKLHJAOF_00808 1.2e-219 patA 2.6.1.1 E Aminotransferase
HKLHJAOF_00809 5.1e-44 ykuJ S Protein of unknown function (DUF1797)
HKLHJAOF_00810 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKLHJAOF_00811 5.3e-80 perR P Belongs to the Fur family
HKLHJAOF_00812 6.1e-35
HKLHJAOF_00813 2.4e-71 S COG NOG38524 non supervised orthologous group
HKLHJAOF_00814 6.8e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HKLHJAOF_00815 9.3e-13
HKLHJAOF_00818 2.7e-213 L Belongs to the 'phage' integrase family
HKLHJAOF_00819 1e-09
HKLHJAOF_00820 4.8e-21
HKLHJAOF_00821 1.1e-97 3.1.21.3 V Type I restriction modification DNA specificity domain
HKLHJAOF_00822 5.8e-19 3.4.21.88 K Peptidase S24-like
HKLHJAOF_00823 5.1e-39 3.4.21.88 K Helix-turn-helix
HKLHJAOF_00824 3.9e-09 K Helix-turn-helix XRE-family like proteins
HKLHJAOF_00825 1.1e-29 kilA K BRO family, N-terminal domain
HKLHJAOF_00826 1.1e-82 S Phage regulatory protein Rha (Phage_pRha)
HKLHJAOF_00833 3.3e-107 S calcium ion binding
HKLHJAOF_00834 3.8e-232 S DNA helicase activity
HKLHJAOF_00837 5.8e-39
HKLHJAOF_00838 3e-65 S magnesium ion binding
HKLHJAOF_00839 7.2e-19
HKLHJAOF_00840 5.4e-26
HKLHJAOF_00841 6.3e-93 S Protein of unknown function (DUF1642)
HKLHJAOF_00843 1.2e-33
HKLHJAOF_00845 9.1e-77
HKLHJAOF_00846 1.4e-12
HKLHJAOF_00847 3.2e-236
HKLHJAOF_00848 8.8e-98 S HNH endonuclease
HKLHJAOF_00849 4.9e-51
HKLHJAOF_00850 2.5e-72 S HNH endonuclease
HKLHJAOF_00851 8.7e-78 S Phage terminase, small subunit
HKLHJAOF_00852 8.7e-165 S Phage Terminase
HKLHJAOF_00853 1.4e-150 S Phage Terminase
HKLHJAOF_00855 1.3e-199 S Phage portal protein
HKLHJAOF_00856 1.7e-26 S peptidase activity
HKLHJAOF_00857 4.4e-28 S peptidase activity
HKLHJAOF_00858 2.3e-76 S peptidase activity
HKLHJAOF_00859 4.2e-15 S peptidase activity
HKLHJAOF_00860 1.2e-35 S exonuclease activity
HKLHJAOF_00862 3.9e-60
HKLHJAOF_00864 1.8e-178 S peptidoglycan catabolic process
HKLHJAOF_00865 3e-43 S peptidoglycan catabolic process
HKLHJAOF_00866 7.9e-78 S peptidoglycan catabolic process
HKLHJAOF_00867 7.2e-20 S peptidoglycan catabolic process
HKLHJAOF_00868 7.8e-41 S phage tail
HKLHJAOF_00869 2.7e-51 S Prophage endopeptidase tail
HKLHJAOF_00870 1.2e-56 cotH M CotH kinase protein
HKLHJAOF_00871 6.1e-48
HKLHJAOF_00872 9.8e-44 hol S Bacteriophage holin
HKLHJAOF_00873 2.1e-31
HKLHJAOF_00874 3.5e-203 M Glycosyl hydrolases family 25
HKLHJAOF_00875 6.7e-09 icaC G Acyltransferase family
HKLHJAOF_00876 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_00877 2.3e-12 icaC G Acyltransferase family
HKLHJAOF_00879 2.6e-99
HKLHJAOF_00880 1.7e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKLHJAOF_00881 2.1e-274 emrY EGP Major facilitator Superfamily
HKLHJAOF_00882 1.3e-81 merR K MerR HTH family regulatory protein
HKLHJAOF_00883 3.3e-217 lmrB EGP Major facilitator Superfamily
HKLHJAOF_00884 4.1e-37 lmrB EGP Major facilitator Superfamily
HKLHJAOF_00885 2.1e-113 S Domain of unknown function (DUF4811)
HKLHJAOF_00886 6.7e-119 3.6.1.27 I Acid phosphatase homologues
HKLHJAOF_00887 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKLHJAOF_00888 5.4e-279 ytgP S Polysaccharide biosynthesis protein
HKLHJAOF_00889 3.4e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKLHJAOF_00890 3.3e-35 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HKLHJAOF_00891 8.9e-137 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKLHJAOF_00892 2.6e-95 FNV0100 F NUDIX domain
HKLHJAOF_00894 4.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HKLHJAOF_00895 6.7e-226 malY 4.4.1.8 E Aminotransferase, class I
HKLHJAOF_00896 2.9e-222 cpdA S Calcineurin-like phosphoesterase
HKLHJAOF_00897 1.5e-37 gcvR T Belongs to the UPF0237 family
HKLHJAOF_00898 1.3e-243 XK27_08635 S UPF0210 protein
HKLHJAOF_00899 1.1e-211 coiA 3.6.4.12 S Competence protein
HKLHJAOF_00900 1.5e-115 yjbH Q Thioredoxin
HKLHJAOF_00901 1.2e-103 yjbK S CYTH
HKLHJAOF_00902 2.7e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
HKLHJAOF_00903 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKLHJAOF_00904 7.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HKLHJAOF_00905 1.2e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKLHJAOF_00906 1.3e-111 cutC P Participates in the control of copper homeostasis
HKLHJAOF_00907 3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKLHJAOF_00908 2.3e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HKLHJAOF_00909 1.2e-61 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HKLHJAOF_00910 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKLHJAOF_00911 7.4e-191 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKLHJAOF_00912 5.7e-172 corA P CorA-like Mg2+ transporter protein
HKLHJAOF_00913 2.4e-153 rrmA 2.1.1.187 H Methyltransferase
HKLHJAOF_00914 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKLHJAOF_00915 5.4e-71 WQ51_03320 S Protein of unknown function (DUF1149)
HKLHJAOF_00916 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HKLHJAOF_00917 6.1e-230 ymfF S Peptidase M16 inactive domain protein
HKLHJAOF_00918 2.2e-243 ymfH S Peptidase M16
HKLHJAOF_00919 1.1e-127 IQ Enoyl-(Acyl carrier protein) reductase
HKLHJAOF_00920 2e-116 ymfM S Helix-turn-helix domain
HKLHJAOF_00921 1.6e-103 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKLHJAOF_00922 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
HKLHJAOF_00923 1.3e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKLHJAOF_00924 1.2e-09
HKLHJAOF_00925 3.6e-21
HKLHJAOF_00926 1.7e-242 rny S Endoribonuclease that initiates mRNA decay
HKLHJAOF_00927 9.5e-118 yvyE 3.4.13.9 S YigZ family
HKLHJAOF_00928 8.2e-235 comFA L Helicase C-terminal domain protein
HKLHJAOF_00929 1.3e-90 comFC S Competence protein
HKLHJAOF_00930 5.4e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKLHJAOF_00931 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKLHJAOF_00932 8.9e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKLHJAOF_00933 1.9e-124 ftsE D ABC transporter
HKLHJAOF_00934 1.8e-159 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HKLHJAOF_00935 3.2e-195 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HKLHJAOF_00936 5.2e-130 K response regulator
HKLHJAOF_00937 1.1e-306 phoR 2.7.13.3 T Histidine kinase
HKLHJAOF_00938 4.4e-155 pstS P Phosphate
HKLHJAOF_00939 3.4e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HKLHJAOF_00940 1.1e-156 pstA P Phosphate transport system permease protein PstA
HKLHJAOF_00941 1.2e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKLHJAOF_00942 7.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKLHJAOF_00943 1e-119 phoU P Plays a role in the regulation of phosphate uptake
HKLHJAOF_00944 4.8e-210 yvlB S Putative adhesin
HKLHJAOF_00945 7.1e-32
HKLHJAOF_00946 1.3e-46 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HKLHJAOF_00947 2.8e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKLHJAOF_00948 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKLHJAOF_00949 3.4e-194 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HKLHJAOF_00950 1.5e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKLHJAOF_00951 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKLHJAOF_00952 6.8e-84 T Transcriptional regulatory protein, C terminal
HKLHJAOF_00953 8.9e-115 T His Kinase A (phosphoacceptor) domain
HKLHJAOF_00954 1.2e-91 V ABC transporter
HKLHJAOF_00955 1.1e-87 V FtsX-like permease family
HKLHJAOF_00956 6.1e-149 V FtsX-like permease family
HKLHJAOF_00957 5.5e-118 yfbR S HD containing hydrolase-like enzyme
HKLHJAOF_00958 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKLHJAOF_00959 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKLHJAOF_00960 6.7e-85 S Short repeat of unknown function (DUF308)
HKLHJAOF_00961 1.3e-165 rapZ S Displays ATPase and GTPase activities
HKLHJAOF_00962 1.7e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HKLHJAOF_00963 1.6e-171 whiA K May be required for sporulation
HKLHJAOF_00964 1.7e-35 ohrR K helix_turn_helix multiple antibiotic resistance protein
HKLHJAOF_00965 1.6e-24 ohrR K helix_turn_helix multiple antibiotic resistance protein
HKLHJAOF_00966 2.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKLHJAOF_00968 3.6e-188 cggR K Putative sugar-binding domain
HKLHJAOF_00969 2.2e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKLHJAOF_00970 1.5e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HKLHJAOF_00971 1.7e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKLHJAOF_00972 3.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKLHJAOF_00973 1.2e-64
HKLHJAOF_00974 3.7e-293 clcA P chloride
HKLHJAOF_00975 1.7e-60
HKLHJAOF_00976 9.3e-31 secG U Preprotein translocase
HKLHJAOF_00977 5.4e-138 est 3.1.1.1 S Serine aminopeptidase, S33
HKLHJAOF_00978 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKLHJAOF_00979 3.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKLHJAOF_00980 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HKLHJAOF_00981 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HKLHJAOF_00982 7.7e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HKLHJAOF_00983 8.7e-50
HKLHJAOF_00984 9.7e-17
HKLHJAOF_00985 6.6e-237 YSH1 S Metallo-beta-lactamase superfamily
HKLHJAOF_00986 4.4e-239 malE G Bacterial extracellular solute-binding protein
HKLHJAOF_00987 1.9e-147 malF G Binding-protein-dependent transport system inner membrane component
HKLHJAOF_00988 2.6e-166 malG P ABC-type sugar transport systems, permease components
HKLHJAOF_00989 1.7e-193 malK P ATPases associated with a variety of cellular activities
HKLHJAOF_00990 4.4e-103 3.2.2.20 K Acetyltransferase (GNAT) domain
HKLHJAOF_00991 9e-92 yxjI
HKLHJAOF_00992 2e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
HKLHJAOF_00993 4.6e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKLHJAOF_00994 8.4e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HKLHJAOF_00995 4.6e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HKLHJAOF_00996 5.4e-164 natA S ABC transporter, ATP-binding protein
HKLHJAOF_00997 4.8e-219 ysdA CP ABC-2 family transporter protein
HKLHJAOF_00998 3.1e-98 dnaQ 2.7.7.7 L DNA polymerase III
HKLHJAOF_00999 1.9e-149 xth 3.1.11.2 L exodeoxyribonuclease III
HKLHJAOF_01000 2.6e-166 murB 1.3.1.98 M Cell wall formation
HKLHJAOF_01001 0.0 yjcE P Sodium proton antiporter
HKLHJAOF_01002 2.9e-96 puuR K Cupin domain
HKLHJAOF_01003 4.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKLHJAOF_01004 1.7e-148 potB P ABC transporter permease
HKLHJAOF_01005 8.9e-145 potC P ABC transporter permease
HKLHJAOF_01006 1.6e-207 potD P ABC transporter
HKLHJAOF_01007 1.1e-80 S Domain of unknown function (DUF5067)
HKLHJAOF_01008 1.1e-59
HKLHJAOF_01010 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HKLHJAOF_01011 2.2e-117 K Transcriptional regulator
HKLHJAOF_01012 5.4e-177 V ABC transporter
HKLHJAOF_01013 8.1e-126 V AAA domain, putative AbiEii toxin, Type IV TA system
HKLHJAOF_01014 1e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKLHJAOF_01015 1.5e-168 ybbR S YbbR-like protein
HKLHJAOF_01016 9.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKLHJAOF_01017 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKLHJAOF_01018 0.0 pepF2 E Oligopeptidase F
HKLHJAOF_01019 3.3e-91 S VanZ like family
HKLHJAOF_01020 3.4e-132 yebC K Transcriptional regulatory protein
HKLHJAOF_01021 1.3e-133 comGA NU Type II IV secretion system protein
HKLHJAOF_01022 7.5e-164 comGB NU type II secretion system
HKLHJAOF_01023 5.1e-48
HKLHJAOF_01025 1.1e-47
HKLHJAOF_01026 1.1e-80
HKLHJAOF_01027 4.6e-49
HKLHJAOF_01028 7.6e-183 ytxK 2.1.1.72 L N-6 DNA Methylase
HKLHJAOF_01029 1.3e-73
HKLHJAOF_01030 1.2e-247 cycA E Amino acid permease
HKLHJAOF_01031 5.8e-143 arbV 2.3.1.51 I Phosphate acyltransferases
HKLHJAOF_01032 2.1e-162 arbx M Glycosyl transferase family 8
HKLHJAOF_01033 2.2e-179 arbY M family 8
HKLHJAOF_01034 2.9e-162 arbZ I Phosphate acyltransferases
HKLHJAOF_01035 0.0 rafA 3.2.1.22 G alpha-galactosidase
HKLHJAOF_01036 1.4e-212 sip L Belongs to the 'phage' integrase family
HKLHJAOF_01037 3.5e-11 K Cro/C1-type HTH DNA-binding domain
HKLHJAOF_01038 7e-43
HKLHJAOF_01039 1.1e-30
HKLHJAOF_01040 7.9e-11
HKLHJAOF_01041 2.4e-21
HKLHJAOF_01042 1.9e-35
HKLHJAOF_01043 1.3e-24
HKLHJAOF_01044 9.4e-155 L Bifunctional DNA primase/polymerase, N-terminal
HKLHJAOF_01045 6.1e-271 S Virulence-associated protein E
HKLHJAOF_01047 2.8e-79 terS L Phage terminase, small subunit
HKLHJAOF_01048 0.0 terL S overlaps another CDS with the same product name
HKLHJAOF_01049 1.1e-20
HKLHJAOF_01050 5.9e-219 S Phage portal protein
HKLHJAOF_01051 1.4e-268 S Phage capsid family
HKLHJAOF_01052 5.1e-47 S Phage gp6-like head-tail connector protein
HKLHJAOF_01053 1.4e-12 S Phage head-tail joining protein
HKLHJAOF_01054 2.9e-16
HKLHJAOF_01055 2.2e-14 ytgB S Transglycosylase associated protein
HKLHJAOF_01056 5.8e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKLHJAOF_01058 1.7e-69 S SdpI/YhfL protein family
HKLHJAOF_01059 3.1e-133 K response regulator
HKLHJAOF_01060 2.4e-273 yclK 2.7.13.3 T Histidine kinase
HKLHJAOF_01061 1.3e-93 yhbS S acetyltransferase
HKLHJAOF_01062 7.6e-31
HKLHJAOF_01063 5.2e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
HKLHJAOF_01064 3.8e-82
HKLHJAOF_01065 5.3e-59
HKLHJAOF_01066 3.8e-251 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HKLHJAOF_01068 1.5e-185 S response to antibiotic
HKLHJAOF_01069 6.2e-108 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HKLHJAOF_01070 3.6e-46 yjgN S Bacterial protein of unknown function (DUF898)
HKLHJAOF_01071 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HKLHJAOF_01072 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKLHJAOF_01073 6.8e-204 camS S sex pheromone
HKLHJAOF_01074 4.9e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKLHJAOF_01075 8.8e-265 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKLHJAOF_01076 6.1e-279 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKLHJAOF_01077 2.9e-193 yegS 2.7.1.107 G Lipid kinase
HKLHJAOF_01078 5.7e-250 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKLHJAOF_01079 4.7e-216 yttB EGP Major facilitator Superfamily
HKLHJAOF_01080 3.5e-146 cof S Sucrose-6F-phosphate phosphohydrolase
HKLHJAOF_01081 1.2e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HKLHJAOF_01082 0.0 pepO 3.4.24.71 O Peptidase family M13
HKLHJAOF_01083 6e-79 K Acetyltransferase (GNAT) domain
HKLHJAOF_01084 4e-164 degV S Uncharacterised protein, DegV family COG1307
HKLHJAOF_01085 5e-120 qmcA O prohibitin homologues
HKLHJAOF_01086 3.2e-29
HKLHJAOF_01087 4.3e-09 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKLHJAOF_01088 4e-133 lys M Glycosyl hydrolases family 25
HKLHJAOF_01089 1.1e-59 S Protein of unknown function (DUF1093)
HKLHJAOF_01090 2e-61 S Domain of unknown function (DUF4828)
HKLHJAOF_01091 2.6e-177 mocA S Oxidoreductase
HKLHJAOF_01092 1.7e-235 yfmL 3.6.4.13 L DEAD DEAH box helicase
HKLHJAOF_01093 6.8e-48 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HKLHJAOF_01094 3.3e-71 S Domain of unknown function (DUF3284)
HKLHJAOF_01096 2.6e-07
HKLHJAOF_01097 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HKLHJAOF_01098 1.6e-238 pepS E Thermophilic metalloprotease (M29)
HKLHJAOF_01099 2.7e-111 K Bacterial regulatory proteins, tetR family
HKLHJAOF_01102 1.2e-260 S Uncharacterized protein conserved in bacteria (DUF2252)
HKLHJAOF_01103 5.1e-179 yihY S Belongs to the UPF0761 family
HKLHJAOF_01104 1.9e-80 fld C Flavodoxin
HKLHJAOF_01105 2.2e-159 map 3.4.11.18 E Methionine Aminopeptidase
HKLHJAOF_01106 3.4e-194 M Glycosyltransferase like family 2
HKLHJAOF_01108 4.5e-29
HKLHJAOF_01109 2.6e-197 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HKLHJAOF_01110 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKLHJAOF_01111 2.6e-266 L Transposase DDE domain
HKLHJAOF_01112 9.1e-119 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HKLHJAOF_01113 4.7e-56 M Glycosyl transferase family 8
HKLHJAOF_01114 2.1e-39 M transferase activity, transferring glycosyl groups
HKLHJAOF_01115 6.2e-220 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKLHJAOF_01116 2.2e-287 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLHJAOF_01117 1.8e-307 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKLHJAOF_01118 0.0 S Bacterial membrane protein YfhO
HKLHJAOF_01119 3e-304 S Psort location CytoplasmicMembrane, score
HKLHJAOF_01120 1.6e-83 S Fic/DOC family
HKLHJAOF_01121 2.1e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HKLHJAOF_01122 2.1e-109
HKLHJAOF_01123 3.3e-167 yqjA S Putative aromatic acid exporter C-terminal domain
HKLHJAOF_01124 2.1e-31 cspC K Cold shock protein
HKLHJAOF_01125 2.4e-26 chpR T PFAM SpoVT AbrB
HKLHJAOF_01126 1.4e-81 yvbK 3.1.3.25 K GNAT family
HKLHJAOF_01127 1.3e-108 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HKLHJAOF_01128 7.9e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKLHJAOF_01129 7.3e-242 pbuX F xanthine permease
HKLHJAOF_01130 3e-204 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKLHJAOF_01131 1.4e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKLHJAOF_01133 1.2e-103
HKLHJAOF_01134 3.4e-32
HKLHJAOF_01135 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_01136 6.2e-65
HKLHJAOF_01137 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKLHJAOF_01138 1.5e-109 vanZ V VanZ like family
HKLHJAOF_01139 2.9e-151 glcU U sugar transport
HKLHJAOF_01140 7.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
HKLHJAOF_01142 5.6e-46 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HKLHJAOF_01143 2e-115 F DNA/RNA non-specific endonuclease
HKLHJAOF_01144 5.6e-74 yttA 2.7.13.3 S Pfam Transposase IS66
HKLHJAOF_01145 3.3e-230 wbbX GT2,GT4 M Glycosyl transferases group 1
HKLHJAOF_01146 1.4e-172 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HKLHJAOF_01147 5.8e-85 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
HKLHJAOF_01155 1.2e-17
HKLHJAOF_01156 2.5e-193 yttB EGP Major facilitator Superfamily
HKLHJAOF_01157 2.2e-284 pipD E Dipeptidase
HKLHJAOF_01161 8.7e-09
HKLHJAOF_01162 1e-131 G Phosphoglycerate mutase family
HKLHJAOF_01163 5.4e-121 K Bacterial regulatory proteins, tetR family
HKLHJAOF_01164 0.0 ycfI V ABC transporter, ATP-binding protein
HKLHJAOF_01165 0.0 yfiC V ABC transporter
HKLHJAOF_01166 7.8e-140 S NADPH-dependent FMN reductase
HKLHJAOF_01167 2.3e-164 1.13.11.2 S glyoxalase
HKLHJAOF_01168 2.2e-190 ampC V Beta-lactamase
HKLHJAOF_01169 1.9e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HKLHJAOF_01170 6e-111 tdk 2.7.1.21 F thymidine kinase
HKLHJAOF_01171 4.8e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKLHJAOF_01172 2.6e-152 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKLHJAOF_01173 1.3e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKLHJAOF_01174 2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKLHJAOF_01175 1.3e-111 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKLHJAOF_01176 3.9e-125 atpB C it plays a direct role in the translocation of protons across the membrane
HKLHJAOF_01177 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKLHJAOF_01178 4.7e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKLHJAOF_01179 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKLHJAOF_01180 2.1e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKLHJAOF_01181 1.2e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKLHJAOF_01182 4.1e-07 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKLHJAOF_01183 1.2e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKLHJAOF_01184 1.6e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HKLHJAOF_01185 1.7e-12
HKLHJAOF_01186 6.4e-32 ywzB S Protein of unknown function (DUF1146)
HKLHJAOF_01187 4.5e-180 mbl D Cell shape determining protein MreB Mrl
HKLHJAOF_01188 1.9e-25 epuA S DNA-directed RNA polymerase subunit beta
HKLHJAOF_01189 1.6e-54 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HKLHJAOF_01190 1.3e-31 S Protein of unknown function (DUF2969)
HKLHJAOF_01191 7.6e-222 rodA D Belongs to the SEDS family
HKLHJAOF_01192 1.1e-47 gcvH E glycine cleavage
HKLHJAOF_01193 3.2e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HKLHJAOF_01194 1.9e-147 P Belongs to the nlpA lipoprotein family
HKLHJAOF_01195 3.8e-148 P Belongs to the nlpA lipoprotein family
HKLHJAOF_01196 2.9e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKLHJAOF_01197 8.8e-106 metI P ABC transporter permease
HKLHJAOF_01198 1.9e-141 sufC O FeS assembly ATPase SufC
HKLHJAOF_01199 5.9e-191 sufD O FeS assembly protein SufD
HKLHJAOF_01200 5.8e-222 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKLHJAOF_01201 2.9e-78 nifU C SUF system FeS assembly protein, NifU family
HKLHJAOF_01202 1.2e-279 sufB O assembly protein SufB
HKLHJAOF_01204 1.8e-26
HKLHJAOF_01205 1.1e-65 yueI S Protein of unknown function (DUF1694)
HKLHJAOF_01206 2e-180 S Protein of unknown function (DUF2785)
HKLHJAOF_01207 4.4e-158 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HKLHJAOF_01208 1.5e-83 usp6 T universal stress protein
HKLHJAOF_01209 1.7e-39
HKLHJAOF_01210 3.3e-237 rarA L recombination factor protein RarA
HKLHJAOF_01211 0.0 6.3.2.2, 6.3.2.4 M Mur ligase middle domain protein
HKLHJAOF_01212 1e-72 yueI S Protein of unknown function (DUF1694)
HKLHJAOF_01213 4.1e-107 yktB S Belongs to the UPF0637 family
HKLHJAOF_01214 2.2e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HKLHJAOF_01215 7.3e-150 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKLHJAOF_01216 3e-122 G Phosphoglycerate mutase family
HKLHJAOF_01217 7.3e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKLHJAOF_01218 1.7e-165 IQ NAD dependent epimerase/dehydratase family
HKLHJAOF_01219 2.7e-137 pnuC H nicotinamide mononucleotide transporter
HKLHJAOF_01220 2.6e-132 dck 2.7.1.74 F deoxynucleoside kinase
HKLHJAOF_01221 1.7e-156 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HKLHJAOF_01222 0.0 oppA E ABC transporter, substratebinding protein
HKLHJAOF_01223 1.8e-151 T GHKL domain
HKLHJAOF_01224 4e-119 T Transcriptional regulatory protein, C terminal
HKLHJAOF_01225 1.9e-167 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
HKLHJAOF_01226 8.2e-129 S ABC-2 family transporter protein
HKLHJAOF_01227 9.4e-161 K Transcriptional regulator
HKLHJAOF_01228 7.2e-79 yphH S Cupin domain
HKLHJAOF_01229 4.2e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HKLHJAOF_01231 2.2e-11 K Psort location Cytoplasmic, score
HKLHJAOF_01232 2e-83 K Psort location Cytoplasmic, score
HKLHJAOF_01233 1.5e-163 2.3.1.128 K Acetyltransferase (GNAT) domain
HKLHJAOF_01234 1.7e-84 K Acetyltransferase (GNAT) domain
HKLHJAOF_01235 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_01236 1.4e-153 S Uncharacterised protein, DegV family COG1307
HKLHJAOF_01237 3.7e-106
HKLHJAOF_01238 4e-102 desR K helix_turn_helix, Lux Regulon
HKLHJAOF_01239 1.8e-198 desK 2.7.13.3 T Histidine kinase
HKLHJAOF_01240 1.6e-129 yvfS V ABC-2 type transporter
HKLHJAOF_01241 4.4e-158 yvfR V ABC transporter
HKLHJAOF_01242 2.5e-275
HKLHJAOF_01243 9.9e-150
HKLHJAOF_01244 2.2e-82 K Acetyltransferase (GNAT) domain
HKLHJAOF_01245 0.0 yhgF K Tex-like protein N-terminal domain protein
HKLHJAOF_01246 3.8e-139 puuD S peptidase C26
HKLHJAOF_01247 5e-227 steT E Amino acid permease
HKLHJAOF_01248 1.1e-133 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HKLHJAOF_01249 1.9e-145 S Domain of unknown function (DUF1998)
HKLHJAOF_01250 2e-275 KL Helicase conserved C-terminal domain
HKLHJAOF_01252 2.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKLHJAOF_01253 1.5e-83 ytsP 1.8.4.14 T GAF domain-containing protein
HKLHJAOF_01254 1.2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKLHJAOF_01255 2.1e-216 iscS2 2.8.1.7 E Aminotransferase class V
HKLHJAOF_01256 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKLHJAOF_01257 1.5e-115 rex K CoA binding domain
HKLHJAOF_01258 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKLHJAOF_01259 9.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKLHJAOF_01260 1.3e-114 S Haloacid dehalogenase-like hydrolase
HKLHJAOF_01261 2.7e-118 radC L DNA repair protein
HKLHJAOF_01262 7.8e-180 mreB D cell shape determining protein MreB
HKLHJAOF_01263 8.5e-151 mreC M Involved in formation and maintenance of cell shape
HKLHJAOF_01264 4.7e-83 mreD M rod shape-determining protein MreD
HKLHJAOF_01265 1.4e-113 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKLHJAOF_01266 1.1e-141 minD D Belongs to the ParA family
HKLHJAOF_01267 4.7e-109 artQ P ABC transporter permease
HKLHJAOF_01268 1.7e-111 glnQ 3.6.3.21 E ABC transporter
HKLHJAOF_01269 4.3e-152 aatB ET ABC transporter substrate-binding protein
HKLHJAOF_01271 3.1e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKLHJAOF_01272 8.6e-09 S Protein of unknown function (DUF4044)
HKLHJAOF_01273 4.2e-53
HKLHJAOF_01274 4.8e-78 mraZ K Belongs to the MraZ family
HKLHJAOF_01275 5.3e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKLHJAOF_01276 6.2e-58 ftsL D cell division protein FtsL
HKLHJAOF_01277 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HKLHJAOF_01278 9.2e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKLHJAOF_01279 1.3e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKLHJAOF_01280 9.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKLHJAOF_01281 1.3e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKLHJAOF_01282 6.9e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKLHJAOF_01283 5.4e-218 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKLHJAOF_01284 6.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKLHJAOF_01285 5.2e-44 yggT D integral membrane protein
HKLHJAOF_01286 6.4e-145 ylmH S S4 domain protein
HKLHJAOF_01287 1.1e-80 divIVA D DivIVA protein
HKLHJAOF_01288 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKLHJAOF_01289 8.2e-37 cspA K Cold shock protein
HKLHJAOF_01290 1.5e-145 pstS P Phosphate
HKLHJAOF_01291 5.2e-262 ydiC1 EGP Major facilitator Superfamily
HKLHJAOF_01292 1.8e-207 yaaN P Toxic anion resistance protein (TelA)
HKLHJAOF_01293 7.6e-115 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HKLHJAOF_01294 7e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HKLHJAOF_01295 5.8e-34
HKLHJAOF_01296 2.4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKLHJAOF_01297 3.4e-219 iscS 2.8.1.7 E Aminotransferase class V
HKLHJAOF_01298 2.6e-58 XK27_04120 S Putative amino acid metabolism
HKLHJAOF_01299 0.0 uvrA2 L ABC transporter
HKLHJAOF_01300 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKLHJAOF_01301 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HKLHJAOF_01302 2e-115 S Repeat protein
HKLHJAOF_01303 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKLHJAOF_01304 2.1e-243 els S Sterol carrier protein domain
HKLHJAOF_01305 6.5e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HKLHJAOF_01306 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKLHJAOF_01307 4.9e-31 ykzG S Belongs to the UPF0356 family
HKLHJAOF_01309 1.7e-73
HKLHJAOF_01310 1.9e-25
HKLHJAOF_01311 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKLHJAOF_01312 4.3e-136 S E1-E2 ATPase
HKLHJAOF_01313 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HKLHJAOF_01314 3.1e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HKLHJAOF_01315 3.7e-243 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKLHJAOF_01316 2.4e-259 lpdA 1.8.1.4 C Dehydrogenase
HKLHJAOF_01317 8.3e-157 1.1.1.27 C L-malate dehydrogenase activity
HKLHJAOF_01318 1.4e-46 yktA S Belongs to the UPF0223 family
HKLHJAOF_01319 5e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HKLHJAOF_01320 0.0 typA T GTP-binding protein TypA
HKLHJAOF_01321 8.5e-210 ftsW D Belongs to the SEDS family
HKLHJAOF_01322 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKLHJAOF_01323 3.8e-57 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HKLHJAOF_01324 1.7e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HKLHJAOF_01325 2.8e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKLHJAOF_01326 3e-193 ylbL T Belongs to the peptidase S16 family
HKLHJAOF_01327 2.6e-107 comEA L Competence protein ComEA
HKLHJAOF_01328 0.0 comEC S Competence protein ComEC
HKLHJAOF_01329 2e-194 holA 2.7.7.7 L DNA polymerase III delta subunit
HKLHJAOF_01330 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
HKLHJAOF_01331 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKLHJAOF_01332 2.2e-117
HKLHJAOF_01333 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKLHJAOF_01334 1.6e-160 S Tetratricopeptide repeat
HKLHJAOF_01335 1.2e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKLHJAOF_01336 2.2e-82 M Protein of unknown function (DUF3737)
HKLHJAOF_01337 1.4e-133 cobB K Sir2 family
HKLHJAOF_01338 1.7e-63 pcaC 4.1.1.44 S Carboxymuconolactone decarboxylase family
HKLHJAOF_01339 9.3e-65 rmeD K helix_turn_helix, mercury resistance
HKLHJAOF_01340 0.0 yknV V ABC transporter
HKLHJAOF_01341 3.2e-197 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKLHJAOF_01342 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKLHJAOF_01343 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HKLHJAOF_01344 1e-47 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HKLHJAOF_01345 2.3e-20
HKLHJAOF_01346 1.5e-259 glnPH2 P ABC transporter permease
HKLHJAOF_01347 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKLHJAOF_01348 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKLHJAOF_01349 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HKLHJAOF_01350 2.7e-155 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKLHJAOF_01351 7.7e-132 fruR K DeoR C terminal sensor domain
HKLHJAOF_01352 1.9e-234 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKLHJAOF_01353 0.0 oatA I Acyltransferase
HKLHJAOF_01354 9.4e-183 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKLHJAOF_01355 4.3e-141 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HKLHJAOF_01356 1.3e-46 yrvD S Lipopolysaccharide assembly protein A domain
HKLHJAOF_01357 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKLHJAOF_01358 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HKLHJAOF_01359 2.2e-54 M1-874 K Domain of unknown function (DUF1836)
HKLHJAOF_01360 1.7e-298 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
HKLHJAOF_01361 1.2e-144
HKLHJAOF_01362 6e-20 S Protein of unknown function (DUF2929)
HKLHJAOF_01363 0.0 dnaE 2.7.7.7 L DNA polymerase
HKLHJAOF_01364 3.5e-177 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKLHJAOF_01365 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HKLHJAOF_01366 7.2e-72 yeaL S Protein of unknown function (DUF441)
HKLHJAOF_01367 3.4e-163 cvfB S S1 domain
HKLHJAOF_01368 3.3e-166 xerD D recombinase XerD
HKLHJAOF_01369 3.4e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKLHJAOF_01370 7.3e-127 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKLHJAOF_01371 3.3e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKLHJAOF_01372 9.4e-138 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKLHJAOF_01373 4.5e-95 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKLHJAOF_01374 1.4e-45 fer C 4Fe-4S single cluster domain of Ferredoxin I
HKLHJAOF_01375 1e-179 ypbB 5.1.3.1 S Helix-turn-helix domain
HKLHJAOF_01376 1.3e-265 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HKLHJAOF_01377 3.8e-55 M Lysin motif
HKLHJAOF_01378 2.6e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HKLHJAOF_01379 1.1e-218 rpsA 1.17.7.4 J Ribosomal protein S1
HKLHJAOF_01380 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HKLHJAOF_01381 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKLHJAOF_01382 3.5e-233 S Tetratricopeptide repeat protein
HKLHJAOF_01383 4.8e-149 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKLHJAOF_01384 2.8e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKLHJAOF_01385 9.6e-85
HKLHJAOF_01386 0.0 yfmR S ABC transporter, ATP-binding protein
HKLHJAOF_01387 4.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKLHJAOF_01388 7.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKLHJAOF_01389 2.1e-114 hly S protein, hemolysin III
HKLHJAOF_01390 1.5e-147 DegV S EDD domain protein, DegV family
HKLHJAOF_01391 7.8e-157 ypmR E GDSL-like Lipase/Acylhydrolase
HKLHJAOF_01392 5.8e-112 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HKLHJAOF_01393 2.1e-96 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKLHJAOF_01394 2.3e-40 yozE S Belongs to the UPF0346 family
HKLHJAOF_01395 3e-257 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HKLHJAOF_01396 3.4e-15
HKLHJAOF_01397 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_01398 3.1e-66 S Psort location Cytoplasmic, score
HKLHJAOF_01399 6e-12
HKLHJAOF_01400 4.8e-131 S Domain of unknown function (DUF4918)
HKLHJAOF_01401 1.8e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKLHJAOF_01402 3.6e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKLHJAOF_01403 1.4e-147 dprA LU DNA protecting protein DprA
HKLHJAOF_01404 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKLHJAOF_01405 3e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKLHJAOF_01406 1.5e-166 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HKLHJAOF_01407 5.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKLHJAOF_01408 5e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKLHJAOF_01409 6.2e-173 lacX 5.1.3.3 G Aldose 1-epimerase
HKLHJAOF_01410 4.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKLHJAOF_01411 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKLHJAOF_01412 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKLHJAOF_01413 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HKLHJAOF_01414 4.3e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKLHJAOF_01415 1.8e-181 K LysR substrate binding domain
HKLHJAOF_01416 9.5e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
HKLHJAOF_01417 2.9e-207 xerS L Belongs to the 'phage' integrase family
HKLHJAOF_01418 0.0 ysaB V FtsX-like permease family
HKLHJAOF_01419 3.8e-134 XK27_05695 V ABC transporter, ATP-binding protein
HKLHJAOF_01420 5.2e-173 T Histidine kinase-like ATPases
HKLHJAOF_01421 4.8e-128 T Transcriptional regulatory protein, C terminal
HKLHJAOF_01422 1.1e-217 EGP Transmembrane secretion effector
HKLHJAOF_01423 7.1e-68 msi198 K Acetyltransferase (GNAT) domain
HKLHJAOF_01424 5.9e-70 K Acetyltransferase (GNAT) domain
HKLHJAOF_01425 2.6e-112 nfnB 1.5.1.34 C Nitroreductase family
HKLHJAOF_01426 1.3e-145 Q Fumarylacetoacetate (FAA) hydrolase family
HKLHJAOF_01427 3.1e-206 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKLHJAOF_01428 6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HKLHJAOF_01429 2.1e-57 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKLHJAOF_01430 3.2e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKLHJAOF_01431 4.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKLHJAOF_01432 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKLHJAOF_01433 2.4e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HKLHJAOF_01434 3.5e-225 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKLHJAOF_01435 2.7e-109 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKLHJAOF_01436 9.2e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKLHJAOF_01437 2.2e-204 hisC 2.6.1.9 E Cys/Met metabolism PLP-dependent enzyme
HKLHJAOF_01438 1.5e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
HKLHJAOF_01439 3.2e-161 degV S EDD domain protein, DegV family
HKLHJAOF_01440 8.1e-09
HKLHJAOF_01441 0.0 FbpA K Fibronectin-binding protein
HKLHJAOF_01442 6.2e-51 S MazG-like family
HKLHJAOF_01443 3.2e-193 pfoS S Phosphotransferase system, EIIC
HKLHJAOF_01444 2.9e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKLHJAOF_01445 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKLHJAOF_01446 2.1e-152 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKLHJAOF_01447 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HKLHJAOF_01448 1e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKLHJAOF_01449 2.5e-239 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKLHJAOF_01450 2.8e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HKLHJAOF_01451 2.6e-236 pyrP F Permease
HKLHJAOF_01452 1.7e-96 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKLHJAOF_01453 5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKLHJAOF_01454 9.2e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKLHJAOF_01455 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HKLHJAOF_01456 2.4e-63 S Family of unknown function (DUF5322)
HKLHJAOF_01457 1.1e-68 rnhA 3.1.26.4 L Ribonuclease HI
HKLHJAOF_01458 1.1e-63 XK27_02070 S Nitroreductase family
HKLHJAOF_01459 1.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKLHJAOF_01460 9.7e-55
HKLHJAOF_01462 1.6e-271 K Mga helix-turn-helix domain
HKLHJAOF_01463 4.5e-38 nrdH O Glutaredoxin
HKLHJAOF_01464 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLHJAOF_01465 1.2e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLHJAOF_01467 4.1e-164 K Transcriptional regulator
HKLHJAOF_01468 0.0 pepO 3.4.24.71 O Peptidase family M13
HKLHJAOF_01469 1.6e-193 lplA 6.3.1.20 H Lipoate-protein ligase
HKLHJAOF_01470 1.9e-33
HKLHJAOF_01471 7.8e-174 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKLHJAOF_01472 3.7e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HKLHJAOF_01474 1.8e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKLHJAOF_01475 1.9e-106 ypsA S Belongs to the UPF0398 family
HKLHJAOF_01476 1.5e-120 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKLHJAOF_01477 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HKLHJAOF_01478 1.2e-85 comEB 3.5.4.12 F ComE operon protein 2
HKLHJAOF_01479 2.4e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKLHJAOF_01480 2.4e-110 dnaD L DnaD domain protein
HKLHJAOF_01481 1.2e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HKLHJAOF_01482 2.4e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HKLHJAOF_01483 2.1e-85 ypmB S Protein conserved in bacteria
HKLHJAOF_01484 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HKLHJAOF_01485 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HKLHJAOF_01486 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKLHJAOF_01487 4.6e-166 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HKLHJAOF_01488 2.1e-177 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HKLHJAOF_01489 3.6e-196 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKLHJAOF_01490 1.3e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HKLHJAOF_01491 4.7e-174
HKLHJAOF_01492 2e-140
HKLHJAOF_01493 2.8e-60 yitW S Iron-sulfur cluster assembly protein
HKLHJAOF_01494 7.3e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HKLHJAOF_01495 1e-271 V (ABC) transporter
HKLHJAOF_01496 2.8e-310 V ABC transporter transmembrane region
HKLHJAOF_01497 1.8e-147 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKLHJAOF_01498 1.7e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
HKLHJAOF_01499 4.4e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKLHJAOF_01500 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKLHJAOF_01501 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HKLHJAOF_01502 1.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HKLHJAOF_01503 2e-94 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
HKLHJAOF_01505 9.6e-38 V ATPases associated with a variety of cellular activities
HKLHJAOF_01506 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_01507 8.2e-65 V ATPases associated with a variety of cellular activities
HKLHJAOF_01508 3.9e-53
HKLHJAOF_01509 4.9e-148 recO L Involved in DNA repair and RecF pathway recombination
HKLHJAOF_01510 1.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKLHJAOF_01511 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKLHJAOF_01512 1.5e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HKLHJAOF_01513 6.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKLHJAOF_01514 2.9e-179 phoH T phosphate starvation-inducible protein PhoH
HKLHJAOF_01515 1.6e-68 yqeY S YqeY-like protein
HKLHJAOF_01516 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HKLHJAOF_01517 7.2e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKLHJAOF_01518 4.7e-168 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKLHJAOF_01519 4.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKLHJAOF_01520 1.1e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HKLHJAOF_01521 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKLHJAOF_01522 1.4e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
HKLHJAOF_01523 1.3e-266
HKLHJAOF_01524 5.6e-158 V ABC transporter
HKLHJAOF_01525 1e-78 FG adenosine 5'-monophosphoramidase activity
HKLHJAOF_01526 5.2e-248 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
HKLHJAOF_01527 7.2e-115 3.1.3.18 J HAD-hyrolase-like
HKLHJAOF_01528 5.2e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKLHJAOF_01529 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKLHJAOF_01530 4e-53
HKLHJAOF_01531 3.9e-128 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKLHJAOF_01532 3e-173 prmA J Ribosomal protein L11 methyltransferase
HKLHJAOF_01533 2e-83 XK27_03960 S Protein of unknown function (DUF3013)
HKLHJAOF_01534 3.2e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HKLHJAOF_01535 3.1e-37
HKLHJAOF_01536 3.1e-60 S Protein of unknown function (DUF1093)
HKLHJAOF_01537 2.3e-26
HKLHJAOF_01538 6.3e-61
HKLHJAOF_01540 9.2e-112 1.6.5.2 S Flavodoxin-like fold
HKLHJAOF_01541 3.8e-91 K Bacterial regulatory proteins, tetR family
HKLHJAOF_01542 1.9e-186 mocA S Oxidoreductase
HKLHJAOF_01543 7.7e-278 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HKLHJAOF_01544 9.9e-299 2.4.1.52 GT4 M Glycosyl transferases group 1
HKLHJAOF_01546 1.3e-302 2.4.1.9, 3.4.24.40 GH68 S peptidase inhibitor activity
HKLHJAOF_01548 6.7e-287
HKLHJAOF_01549 1.9e-124
HKLHJAOF_01550 3.3e-186
HKLHJAOF_01551 5.3e-147 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
HKLHJAOF_01552 1.2e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HKLHJAOF_01553 3.7e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKLHJAOF_01554 2e-94 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKLHJAOF_01555 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HKLHJAOF_01556 7.1e-62
HKLHJAOF_01557 9.4e-83 6.3.3.2 S ASCH
HKLHJAOF_01558 5.9e-32
HKLHJAOF_01559 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKLHJAOF_01560 4.1e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKLHJAOF_01561 1e-286 dnaK O Heat shock 70 kDa protein
HKLHJAOF_01562 5.2e-99 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKLHJAOF_01563 8.4e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKLHJAOF_01564 1.6e-224 hemN H Involved in the biosynthesis of porphyrin-containing compound
HKLHJAOF_01565 7.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HKLHJAOF_01566 1.3e-160 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKLHJAOF_01567 6.7e-119 terC P membrane
HKLHJAOF_01568 4.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKLHJAOF_01569 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKLHJAOF_01570 5.4e-44 ylxQ J ribosomal protein
HKLHJAOF_01571 1.5e-46 ylxR K Protein of unknown function (DUF448)
HKLHJAOF_01572 1e-202 nusA K Participates in both transcription termination and antitermination
HKLHJAOF_01573 1e-84 rimP J Required for maturation of 30S ribosomal subunits
HKLHJAOF_01574 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKLHJAOF_01575 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKLHJAOF_01576 4.1e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HKLHJAOF_01577 7.3e-141 cdsA 2.7.7.41 S Belongs to the CDS family
HKLHJAOF_01578 9.5e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKLHJAOF_01579 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKLHJAOF_01580 8.5e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HKLHJAOF_01581 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKLHJAOF_01582 1.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HKLHJAOF_01583 1.3e-47 yazA L GIY-YIG catalytic domain protein
HKLHJAOF_01584 4.8e-134 yabB 2.1.1.223 L Methyltransferase small domain
HKLHJAOF_01585 2.2e-122 plsC 2.3.1.51 I Acyltransferase
HKLHJAOF_01586 5e-201 bcaP E Amino Acid
HKLHJAOF_01587 2.6e-138 yejC S Protein of unknown function (DUF1003)
HKLHJAOF_01588 0.0 mdlB V ABC transporter
HKLHJAOF_01589 0.0 mdlA V ABC transporter
HKLHJAOF_01590 4.8e-29 yneF S UPF0154 protein
HKLHJAOF_01591 1.1e-37 ynzC S UPF0291 protein
HKLHJAOF_01592 1.1e-25
HKLHJAOF_01593 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKLHJAOF_01594 3.1e-147 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HKLHJAOF_01595 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKLHJAOF_01596 8.4e-38 ylqC S Belongs to the UPF0109 family
HKLHJAOF_01597 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HKLHJAOF_01598 1.2e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKLHJAOF_01599 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKLHJAOF_01600 6.8e-24
HKLHJAOF_01601 8.8e-53
HKLHJAOF_01602 1.3e-182 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKLHJAOF_01603 0.0 smc D Required for chromosome condensation and partitioning
HKLHJAOF_01604 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKLHJAOF_01605 0.0 oppA1 E ABC transporter substrate-binding protein
HKLHJAOF_01606 8.2e-136 oppC EP Binding-protein-dependent transport system inner membrane component
HKLHJAOF_01607 2.8e-174 oppB P ABC transporter permease
HKLHJAOF_01608 5.3e-178 oppF P Belongs to the ABC transporter superfamily
HKLHJAOF_01609 4.4e-194 oppD P Belongs to the ABC transporter superfamily
HKLHJAOF_01610 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKLHJAOF_01611 1.5e-186 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKLHJAOF_01612 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKLHJAOF_01613 4.7e-286 yloV S DAK2 domain fusion protein YloV
HKLHJAOF_01614 2.3e-57 asp S Asp23 family, cell envelope-related function
HKLHJAOF_01615 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HKLHJAOF_01616 1.3e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
HKLHJAOF_01617 9.7e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HKLHJAOF_01618 1.9e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKLHJAOF_01619 0.0 KLT serine threonine protein kinase
HKLHJAOF_01620 2e-135 stp 3.1.3.16 T phosphatase
HKLHJAOF_01621 1e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKLHJAOF_01622 1.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKLHJAOF_01623 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKLHJAOF_01624 5.2e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKLHJAOF_01625 2.9e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKLHJAOF_01626 3.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HKLHJAOF_01627 4.7e-120 rssA S Patatin-like phospholipase
HKLHJAOF_01628 6e-51
HKLHJAOF_01629 5.7e-308 recN L May be involved in recombinational repair of damaged DNA
HKLHJAOF_01630 2e-74 argR K Regulates arginine biosynthesis genes
HKLHJAOF_01631 5.2e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HKLHJAOF_01632 1.8e-145 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKLHJAOF_01633 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKLHJAOF_01634 2.1e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKLHJAOF_01635 5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKLHJAOF_01636 2e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKLHJAOF_01637 1.5e-72 yqhY S Asp23 family, cell envelope-related function
HKLHJAOF_01638 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKLHJAOF_01639 7e-203 ypdF 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HKLHJAOF_01640 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HKLHJAOF_01641 1.2e-55 ysxB J Cysteine protease Prp
HKLHJAOF_01642 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HKLHJAOF_01643 3.8e-32
HKLHJAOF_01644 4.1e-14
HKLHJAOF_01645 2.5e-233 ywhK S Membrane
HKLHJAOF_01647 1.1e-263 V ABC transporter transmembrane region
HKLHJAOF_01648 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKLHJAOF_01649 5.8e-263 glnA 6.3.1.2 E glutamine synthetase
HKLHJAOF_01650 1e-60 glnR K Transcriptional regulator
HKLHJAOF_01651 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HKLHJAOF_01652 6.5e-240 ynbB 4.4.1.1 P aluminum resistance
HKLHJAOF_01653 5.7e-180 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKLHJAOF_01654 9.8e-25 WQ51_02665 S Protein of unknown function (DUF3042)
HKLHJAOF_01655 3.7e-72 yqhL P Rhodanese-like protein
HKLHJAOF_01656 2e-177 glk 2.7.1.2 G Glucokinase
HKLHJAOF_01657 1.1e-40 yqgQ S Bacterial protein of unknown function (DUF910)
HKLHJAOF_01658 9.6e-121 gluP 3.4.21.105 S Peptidase, S54 family
HKLHJAOF_01659 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HKLHJAOF_01660 0.0 S Bacterial membrane protein YfhO
HKLHJAOF_01661 2.9e-53 yneR S Belongs to the HesB IscA family
HKLHJAOF_01662 5.8e-115 vraR K helix_turn_helix, Lux Regulon
HKLHJAOF_01663 2.3e-182 vraS 2.7.13.3 T Histidine kinase
HKLHJAOF_01664 8.9e-122 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HKLHJAOF_01665 9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKLHJAOF_01666 6.9e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HKLHJAOF_01667 1.5e-206 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKLHJAOF_01668 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKLHJAOF_01669 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKLHJAOF_01670 2.6e-67 yodB K Transcriptional regulator, HxlR family
HKLHJAOF_01671 5.6e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKLHJAOF_01672 1.1e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKLHJAOF_01673 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HKLHJAOF_01674 4.5e-180 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKLHJAOF_01675 5.2e-287 arlS 2.7.13.3 T Histidine kinase
HKLHJAOF_01676 7.9e-123 K response regulator
HKLHJAOF_01677 7.2e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKLHJAOF_01678 1.6e-94 yceD S Uncharacterized ACR, COG1399
HKLHJAOF_01679 5.5e-206 ylbM S Belongs to the UPF0348 family
HKLHJAOF_01680 1.7e-139 yqeM Q Methyltransferase
HKLHJAOF_01681 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKLHJAOF_01682 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HKLHJAOF_01683 9.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKLHJAOF_01684 1.2e-46 yhbY J RNA-binding protein
HKLHJAOF_01685 3.4e-216 yqeH S Ribosome biogenesis GTPase YqeH
HKLHJAOF_01686 2.4e-95 yqeG S HAD phosphatase, family IIIA
HKLHJAOF_01687 2e-166 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKLHJAOF_01688 1.2e-190 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKLHJAOF_01689 1.8e-121 mhqD S Dienelactone hydrolase family
HKLHJAOF_01690 3.7e-179 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
HKLHJAOF_01691 1e-99 yvdD 3.2.2.10 S Belongs to the LOG family
HKLHJAOF_01692 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKLHJAOF_01693 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HKLHJAOF_01694 8.9e-78 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKLHJAOF_01695 8.8e-236 spoVK O ATPase family associated with various cellular activities (AAA)
HKLHJAOF_01696 3.5e-12
HKLHJAOF_01697 4.2e-37 yfjR K WYL domain
HKLHJAOF_01698 6.5e-125 S SseB protein N-terminal domain
HKLHJAOF_01699 5.5e-65
HKLHJAOF_01700 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKLHJAOF_01701 1.2e-169 dnaI L Primosomal protein DnaI
HKLHJAOF_01702 2.1e-249 dnaB L replication initiation and membrane attachment
HKLHJAOF_01703 3.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKLHJAOF_01704 2.3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKLHJAOF_01705 1.5e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKLHJAOF_01706 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKLHJAOF_01707 1.3e-117 ybhL S Inhibitor of apoptosis-promoting Bax1
HKLHJAOF_01708 1.1e-187 S Cell surface protein
HKLHJAOF_01710 2.1e-135 S WxL domain surface cell wall-binding
HKLHJAOF_01711 0.0 N domain, Protein
HKLHJAOF_01712 5.3e-265 K Mga helix-turn-helix domain
HKLHJAOF_01713 4.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HKLHJAOF_01714 2.8e-28 sftA D Belongs to the FtsK SpoIIIE SftA family
HKLHJAOF_01715 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HKLHJAOF_01717 1.2e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKLHJAOF_01718 7.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKLHJAOF_01720 4.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKLHJAOF_01721 1.2e-148 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HKLHJAOF_01723 9e-223 ecsB U ABC transporter
HKLHJAOF_01724 4.9e-131 ecsA V ABC transporter, ATP-binding protein
HKLHJAOF_01725 5.5e-74 hit FG histidine triad
HKLHJAOF_01726 7.4e-48 yhaH S YtxH-like protein
HKLHJAOF_01727 2.6e-158 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKLHJAOF_01728 2.1e-182 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKLHJAOF_01729 4.6e-55 yheA S Control of competence regulator ComK, YlbF/YmcA
HKLHJAOF_01730 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKLHJAOF_01731 3.6e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKLHJAOF_01732 2e-74 argR K Regulates arginine biosynthesis genes
HKLHJAOF_01733 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HKLHJAOF_01735 5.9e-67
HKLHJAOF_01736 6.1e-22
HKLHJAOF_01737 1.2e-177 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HKLHJAOF_01738 4.5e-303 glpQ 3.1.4.46 C phosphodiesterase
HKLHJAOF_01739 5.1e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKLHJAOF_01740 1.5e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKLHJAOF_01741 4.6e-137 yhfI S Metallo-beta-lactamase superfamily
HKLHJAOF_01742 7.6e-91 traP 1.14.99.57, 6.2.1.3 S Antibiotic biosynthesis monooxygenase
HKLHJAOF_01743 0.0 V ABC transporter (permease)
HKLHJAOF_01744 2.6e-138 bceA V ABC transporter
HKLHJAOF_01745 1e-122 K response regulator
HKLHJAOF_01746 1.3e-207 T PhoQ Sensor
HKLHJAOF_01747 3.2e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKLHJAOF_01748 0.0 copB 3.6.3.4 P P-type ATPase
HKLHJAOF_01749 1.6e-76 copR K Copper transport repressor CopY TcrY
HKLHJAOF_01750 3.6e-219 purD 6.3.4.13 F Belongs to the GARS family
HKLHJAOF_01751 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HKLHJAOF_01752 7.8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKLHJAOF_01753 2.1e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HKLHJAOF_01754 4e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKLHJAOF_01755 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKLHJAOF_01756 3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKLHJAOF_01757 6.4e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKLHJAOF_01758 2.3e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HKLHJAOF_01759 5.1e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKLHJAOF_01760 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKLHJAOF_01761 1.6e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
HKLHJAOF_01763 1.2e-253 iolT EGP Major facilitator Superfamily
HKLHJAOF_01764 7.4e-12
HKLHJAOF_01765 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKLHJAOF_01766 2.7e-39 ptsH G phosphocarrier protein HPR
HKLHJAOF_01767 2e-28
HKLHJAOF_01768 0.0 clpE O Belongs to the ClpA ClpB family
HKLHJAOF_01769 4.3e-46 XK27_09445 S Domain of unknown function (DUF1827)
HKLHJAOF_01770 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKLHJAOF_01771 5.1e-243 hlyX S Transporter associated domain
HKLHJAOF_01772 6.8e-207 yueF S AI-2E family transporter
HKLHJAOF_01773 8.6e-75 S Acetyltransferase (GNAT) domain
HKLHJAOF_01774 2.8e-96
HKLHJAOF_01775 4e-104 ygaC J Belongs to the UPF0374 family
HKLHJAOF_01776 6.5e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
HKLHJAOF_01777 2.6e-291 frvR K Mga helix-turn-helix domain
HKLHJAOF_01778 6e-64
HKLHJAOF_01779 4e-251 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKLHJAOF_01780 3.7e-79 F Nucleoside 2-deoxyribosyltransferase
HKLHJAOF_01781 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKLHJAOF_01783 1.5e-219 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HKLHJAOF_01784 6.9e-210 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
HKLHJAOF_01785 2.2e-210 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HKLHJAOF_01786 2e-46
HKLHJAOF_01787 6.3e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HKLHJAOF_01788 1.8e-101 V Restriction endonuclease
HKLHJAOF_01789 1.8e-158 5.1.3.3 G Aldose 1-epimerase
HKLHJAOF_01790 4.4e-211 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HKLHJAOF_01791 4.4e-101 S ECF transporter, substrate-specific component
HKLHJAOF_01793 6.6e-81 yodP 2.3.1.264 K FR47-like protein
HKLHJAOF_01794 1.3e-81 ydcK S Belongs to the SprT family
HKLHJAOF_01795 2.8e-129 XK27_08845 S ABC transporter, ATP-binding protein
HKLHJAOF_01796 5.6e-129 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HKLHJAOF_01797 4e-176 XK27_08835 S ABC transporter
HKLHJAOF_01798 6.2e-73
HKLHJAOF_01799 0.0 pacL 3.6.3.8 P P-type ATPase
HKLHJAOF_01800 2.1e-216 V Beta-lactamase
HKLHJAOF_01801 3.7e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKLHJAOF_01802 1.3e-221 V Beta-lactamase
HKLHJAOF_01803 6.1e-274 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKLHJAOF_01804 6.6e-125 gntR1 K UbiC transcription regulator-associated domain protein
HKLHJAOF_01805 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKLHJAOF_01806 1.3e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKLHJAOF_01807 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
HKLHJAOF_01808 1e-262 sprD D Domain of Unknown Function (DUF1542)
HKLHJAOF_01809 1.9e-275 mga K Mga helix-turn-helix domain
HKLHJAOF_01811 1.6e-157 yjjH S Calcineurin-like phosphoesterase
HKLHJAOF_01812 1.2e-256 dtpT U amino acid peptide transporter
HKLHJAOF_01813 0.0 macB_3 V ABC transporter, ATP-binding protein
HKLHJAOF_01814 1.4e-65
HKLHJAOF_01815 2.1e-73 S function, without similarity to other proteins
HKLHJAOF_01816 9.9e-261 G MFS/sugar transport protein
HKLHJAOF_01817 1e-231 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
HKLHJAOF_01818 1e-56
HKLHJAOF_01819 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
HKLHJAOF_01820 2.7e-24 S Virus attachment protein p12 family
HKLHJAOF_01821 1.2e-247 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HKLHJAOF_01822 4.3e-141 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HKLHJAOF_01823 5.2e-99 feoA P FeoA
HKLHJAOF_01824 5.2e-106 E lipolytic protein G-D-S-L family
HKLHJAOF_01825 3.5e-88 E AAA domain
HKLHJAOF_01828 2.9e-119 ywnB S NAD(P)H-binding
HKLHJAOF_01829 1.1e-91 S MucBP domain
HKLHJAOF_01830 1.3e-85
HKLHJAOF_01832 9.3e-13
HKLHJAOF_01833 6.8e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HKLHJAOF_01834 2.4e-71 S COG NOG38524 non supervised orthologous group
HKLHJAOF_01837 6.1e-35
HKLHJAOF_01838 7.6e-212 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKLHJAOF_01839 2.4e-300 frvR K Mga helix-turn-helix domain
HKLHJAOF_01840 2.4e-297 frvR K Mga helix-turn-helix domain
HKLHJAOF_01841 1.6e-266 lysP E amino acid
HKLHJAOF_01843 5.3e-130 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HKLHJAOF_01844 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HKLHJAOF_01845 1.6e-97
HKLHJAOF_01846 1.6e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
HKLHJAOF_01847 1.2e-07
HKLHJAOF_01848 9.5e-189 S Bacterial protein of unknown function (DUF916)
HKLHJAOF_01849 8.4e-102
HKLHJAOF_01850 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKLHJAOF_01851 2.3e-159 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HKLHJAOF_01852 1.7e-156 I alpha/beta hydrolase fold
HKLHJAOF_01853 1.3e-47
HKLHJAOF_01854 6.5e-69
HKLHJAOF_01855 7.9e-46
HKLHJAOF_01856 1e-156 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKLHJAOF_01857 7.2e-124 citR K FCD
HKLHJAOF_01858 3.8e-265 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
HKLHJAOF_01859 5.2e-101 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HKLHJAOF_01860 9.8e-283 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HKLHJAOF_01861 2.6e-155 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HKLHJAOF_01862 2.2e-48 citD C Covalent carrier of the coenzyme of citrate lyase
HKLHJAOF_01863 4.2e-181 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKLHJAOF_01865 1e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
HKLHJAOF_01866 8.7e-37 gcdC 2.3.1.12 I Biotin-requiring enzyme
HKLHJAOF_01867 3.8e-51
HKLHJAOF_01868 2.2e-241 citM C Citrate transporter
HKLHJAOF_01869 1.3e-41
HKLHJAOF_01870 2.4e-95 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HKLHJAOF_01871 2.5e-86 K Acetyltransferase (GNAT) domain
HKLHJAOF_01872 3.9e-105 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HKLHJAOF_01873 1.8e-56 K Transcriptional regulator PadR-like family
HKLHJAOF_01874 4.6e-64 ORF00048
HKLHJAOF_01875 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HKLHJAOF_01876 6.3e-168 yjjC V ABC transporter
HKLHJAOF_01877 6.1e-283 M Exporter of polyketide antibiotics
HKLHJAOF_01878 8.9e-113 K Transcriptional regulator
HKLHJAOF_01879 6.5e-257 ypiB EGP Major facilitator Superfamily
HKLHJAOF_01880 1.1e-127 S membrane transporter protein
HKLHJAOF_01881 8.3e-185 K Helix-turn-helix domain
HKLHJAOF_01882 1.7e-159 S Alpha beta hydrolase
HKLHJAOF_01883 3.6e-61 yvoA_1 K Transcriptional regulator, GntR family
HKLHJAOF_01884 9.4e-127 skfE V ATPases associated with a variety of cellular activities
HKLHJAOF_01885 6.2e-14
HKLHJAOF_01886 2.6e-266 L Transposase DDE domain
HKLHJAOF_01887 2.4e-155
HKLHJAOF_01888 4.9e-88 V ATPases associated with a variety of cellular activities
HKLHJAOF_01889 1.3e-162 oppF P Oligopeptide/dipeptide transporter, C-terminal region
HKLHJAOF_01890 2.2e-196 oppD P Oligopeptide/dipeptide transporter, C-terminal region
HKLHJAOF_01891 1.7e-48
HKLHJAOF_01892 3e-173 amiD P N-terminal TM domain of oligopeptide transport permease C
HKLHJAOF_01893 1e-168 oppB P Binding-protein-dependent transport system inner membrane component
HKLHJAOF_01894 2.1e-299 E Bacterial extracellular solute-binding proteins, family 5 Middle
HKLHJAOF_01895 2.4e-35
HKLHJAOF_01896 6.4e-288 V ABC transporter transmembrane region
HKLHJAOF_01897 5.6e-281 V ABC transporter transmembrane region
HKLHJAOF_01898 9.3e-68 S Iron-sulphur cluster biosynthesis
HKLHJAOF_01899 9e-137 2.7.1.39 S Phosphotransferase enzyme family
HKLHJAOF_01900 1.5e-114 zmp3 O Zinc-dependent metalloprotease
HKLHJAOF_01901 2.7e-23 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HKLHJAOF_01903 1e-66 lytN 3.5.1.104 M LysM domain
HKLHJAOF_01904 0.0 lytN 3.5.1.104 M LysM domain
HKLHJAOF_01906 8e-49 lciIC K Helix-turn-helix XRE-family like proteins
HKLHJAOF_01907 5.9e-94 L restriction endonuclease
HKLHJAOF_01908 5.8e-37 L Plasmid pRiA4b ORF-3-like protein
HKLHJAOF_01910 1.3e-24 K Cro/C1-type HTH DNA-binding domain
HKLHJAOF_01915 1.6e-13 M LysM domain
HKLHJAOF_01916 4.6e-56
HKLHJAOF_01917 5.6e-79 K Putative DNA-binding domain
HKLHJAOF_01919 1.5e-44 S Abortive infection C-terminus
HKLHJAOF_01920 3.9e-160 L Belongs to the 'phage' integrase family
HKLHJAOF_01921 9.3e-11 S Domain of unknown function (DUF3173)
HKLHJAOF_01922 4.8e-81 K Replication initiation factor
HKLHJAOF_01923 6.5e-58 3.6.4.12 L Viral (Superfamily 1) RNA helicase
HKLHJAOF_01924 6.7e-112 L AAA domain
HKLHJAOF_01925 1.2e-145 pstS P T5orf172
HKLHJAOF_01926 3.3e-291 yeeB L DEAD-like helicases superfamily
HKLHJAOF_01927 0.0 yeeA V Type II restriction enzyme, methylase subunits
HKLHJAOF_01928 2.1e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HKLHJAOF_01929 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HKLHJAOF_01930 4.4e-53
HKLHJAOF_01931 2.4e-41
HKLHJAOF_01932 1.2e-274 pipD E Dipeptidase
HKLHJAOF_01933 1.2e-82 ykhA 3.1.2.20 I Thioesterase superfamily
HKLHJAOF_01934 0.0 helD 3.6.4.12 L DNA helicase
HKLHJAOF_01935 2.3e-27
HKLHJAOF_01936 0.0 yjbQ P TrkA C-terminal domain protein
HKLHJAOF_01937 3.2e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HKLHJAOF_01938 2.9e-81 yjhE S Phage tail protein
HKLHJAOF_01939 4.1e-216 mntH P H( )-stimulated, divalent metal cation uptake system
HKLHJAOF_01940 5.6e-183 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HKLHJAOF_01941 1.2e-128 pgm3 G Phosphoglycerate mutase family
HKLHJAOF_01942 3.8e-170 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HKLHJAOF_01943 0.0 V FtsX-like permease family
HKLHJAOF_01944 1.2e-135 cysA V ABC transporter, ATP-binding protein
HKLHJAOF_01945 0.0 E amino acid
HKLHJAOF_01946 1.4e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HKLHJAOF_01947 6.9e-237 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKLHJAOF_01948 5.7e-111 nodB3 G Polysaccharide deacetylase
HKLHJAOF_01949 0.0 M Sulfatase
HKLHJAOF_01950 3e-174 S EpsG family
HKLHJAOF_01951 7.4e-83 epsG 2.7.10.1 D Capsular exopolysaccharide family
HKLHJAOF_01952 1.6e-99 ywqC M capsule polysaccharide biosynthetic process
HKLHJAOF_01953 1.6e-247 S polysaccharide biosynthetic process
HKLHJAOF_01954 3.8e-199 M Glycosyl transferases group 1
HKLHJAOF_01955 1.8e-120 tagF 2.7.8.12 M Glycosyltransferase like family 2
HKLHJAOF_01956 1.3e-222 S Bacterial membrane protein, YfhO
HKLHJAOF_01957 2.4e-300 M Glycosyl hydrolases family 25
HKLHJAOF_01958 5.8e-179 M Dolichyl-phosphate-mannose-protein mannosyltransferase
HKLHJAOF_01959 1.9e-112 icaC M Acyltransferase family
HKLHJAOF_01960 5.8e-159 ykoT GT2 M Glycosyl transferase family 2
HKLHJAOF_01961 1.9e-198 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKLHJAOF_01962 1.6e-85
HKLHJAOF_01963 1.5e-253 wcaJ M Bacterial sugar transferase
HKLHJAOF_01964 1.4e-133 M Glycosyltransferase sugar-binding region containing DXD motif
HKLHJAOF_01965 2.1e-113 tuaG GT2 M Glycosyltransferase like family 2
HKLHJAOF_01966 9.2e-175 cps2D 5.1.3.2 M RmlD substrate binding domain
HKLHJAOF_01967 1.1e-110 glnP P ABC transporter permease
HKLHJAOF_01968 7.9e-109 gluC P ABC transporter permease
HKLHJAOF_01969 6.5e-148 glnH ET ABC transporter substrate-binding protein
HKLHJAOF_01970 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKLHJAOF_01971 1.3e-171
HKLHJAOF_01973 5.6e-85 zur P Belongs to the Fur family
HKLHJAOF_01974 1.8e-08
HKLHJAOF_01975 9.3e-112 gmk2 2.7.4.8 F Guanylate kinase
HKLHJAOF_01976 2.8e-67 K Acetyltransferase (GNAT) domain
HKLHJAOF_01977 5.6e-124 spl M NlpC/P60 family
HKLHJAOF_01978 2e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKLHJAOF_01979 2.6e-161 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKLHJAOF_01980 1.4e-53 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHJAOF_01981 3.9e-173 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKLHJAOF_01982 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HKLHJAOF_01983 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKLHJAOF_01984 3.1e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKLHJAOF_01985 1.7e-23 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HKLHJAOF_01986 9.5e-155 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HKLHJAOF_01987 1.7e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKLHJAOF_01988 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKLHJAOF_01989 2.6e-266 L Transposase DDE domain
HKLHJAOF_01990 4.7e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HKLHJAOF_01991 1.3e-112 ylcC 3.4.22.70 M Sortase family
HKLHJAOF_01992 3.4e-144 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKLHJAOF_01993 0.0 fbp 3.1.3.11 G phosphatase activity
HKLHJAOF_01994 5.7e-65 nrp 1.20.4.1 P ArsC family
HKLHJAOF_01995 0.0 clpL O associated with various cellular activities
HKLHJAOF_01996 7.6e-143 ywqE 3.1.3.48 GM PHP domain protein
HKLHJAOF_01997 2.4e-156 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HKLHJAOF_01998 9.2e-76 cpsE M Bacterial sugar transferase
HKLHJAOF_01999 1.5e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKLHJAOF_02000 1.3e-201 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKLHJAOF_02001 8.6e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKLHJAOF_02002 2.2e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKLHJAOF_02003 7.7e-63 wcmJ S SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
HKLHJAOF_02004 1.8e-57 cps1B GT2,GT4 M Glycosyl transferases group 1
HKLHJAOF_02005 6.6e-07 S EpsG family
HKLHJAOF_02006 2.5e-72 rgpB GT2 M Glycosyl transferase family 2
HKLHJAOF_02007 1.1e-25 rfbF GT2 V Glycosyl transferase, family 2
HKLHJAOF_02008 3.3e-43 wbbK M Glycosyl transferases group 1
HKLHJAOF_02009 8.9e-38 wbbL S Glycosyl transferase family 2
HKLHJAOF_02010 3e-89 cps2J S Polysaccharide biosynthesis protein
HKLHJAOF_02011 2.6e-111 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HKLHJAOF_02012 1e-109 epsB M biosynthesis protein
HKLHJAOF_02013 2.8e-131 E lipolytic protein G-D-S-L family
HKLHJAOF_02014 1.1e-81 ccl S QueT transporter
HKLHJAOF_02015 1.5e-124 IQ Enoyl-(Acyl carrier protein) reductase
HKLHJAOF_02016 1.4e-36 XK27_01315 S Protein of unknown function (DUF2829)
HKLHJAOF_02017 5e-48 K Cro/C1-type HTH DNA-binding domain
HKLHJAOF_02018 3.3e-115 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
HKLHJAOF_02019 1.5e-180 oppF P Belongs to the ABC transporter superfamily
HKLHJAOF_02020 1.3e-196 oppD P Belongs to the ABC transporter superfamily
HKLHJAOF_02021 1.4e-176 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHJAOF_02022 3e-162 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHJAOF_02023 7.4e-305 oppA E ABC transporter, substratebinding protein
HKLHJAOF_02024 1.8e-254 EGP Major facilitator Superfamily
HKLHJAOF_02025 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKLHJAOF_02026 6.4e-128 yrjD S LUD domain
HKLHJAOF_02027 1e-289 lutB C 4Fe-4S dicluster domain
HKLHJAOF_02028 4.7e-148 lutA C Cysteine-rich domain
HKLHJAOF_02029 9.1e-101
HKLHJAOF_02030 2.8e-52 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HKLHJAOF_02031 1.5e-211 S Bacterial protein of unknown function (DUF871)
HKLHJAOF_02032 1.8e-69 S Domain of unknown function (DUF3284)
HKLHJAOF_02033 4e-270 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHJAOF_02034 0.0 rafA 3.2.1.22 G alpha-galactosidase
HKLHJAOF_02035 1.4e-133 S Belongs to the UPF0246 family
HKLHJAOF_02036 9.1e-133 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
HKLHJAOF_02037 1.4e-84 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
HKLHJAOF_02038 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
HKLHJAOF_02039 1.3e-108
HKLHJAOF_02040 2e-101 S WxL domain surface cell wall-binding
HKLHJAOF_02041 1e-145 frlD 2.7.1.218 G pfkB family carbohydrate kinase
HKLHJAOF_02042 5.7e-286 G Phosphodiester glycosidase
HKLHJAOF_02044 1.2e-288 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
HKLHJAOF_02045 6.9e-206 S Protein of unknown function (DUF917)
HKLHJAOF_02046 3.5e-222 F Permease for cytosine/purines, uracil, thiamine, allantoin
HKLHJAOF_02047 1.3e-116
HKLHJAOF_02048 6.1e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HKLHJAOF_02049 2e-166 L Belongs to the 'phage' integrase family
HKLHJAOF_02050 8.2e-67 3.1.21.3 V Type I restriction modification DNA specificity domain protein
HKLHJAOF_02051 1.9e-215 hsdM 2.1.1.72 V type I restriction-modification system
HKLHJAOF_02052 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HKLHJAOF_02053 7e-212 ykiI
HKLHJAOF_02054 0.0 pip V domain protein
HKLHJAOF_02055 0.0 scrA 2.7.1.211 G phosphotransferase system
HKLHJAOF_02056 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HKLHJAOF_02057 4.4e-175 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HKLHJAOF_02058 9.4e-299 scrB 3.2.1.26 GH32 G invertase
HKLHJAOF_02060 7.8e-160 azoB GM NmrA-like family
HKLHJAOF_02061 1.9e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HKLHJAOF_02062 2e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HKLHJAOF_02063 5.3e-150 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKLHJAOF_02064 3.6e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HKLHJAOF_02065 1.2e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKLHJAOF_02066 1.1e-43 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKLHJAOF_02067 2e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKLHJAOF_02068 2.8e-126 IQ reductase
HKLHJAOF_02069 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HKLHJAOF_02070 2.4e-173 fabK 1.3.1.9 S Nitronate monooxygenase
HKLHJAOF_02071 4.5e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKLHJAOF_02072 1.8e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKLHJAOF_02073 4.7e-76 marR K Winged helix DNA-binding domain
HKLHJAOF_02074 9e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HKLHJAOF_02075 2.2e-190 I carboxylic ester hydrolase activity
HKLHJAOF_02076 2e-227 bdhA C Iron-containing alcohol dehydrogenase
HKLHJAOF_02077 7.1e-62 P Rhodanese-like domain
HKLHJAOF_02078 5.7e-84 yetL K helix_turn_helix multiple antibiotic resistance protein
HKLHJAOF_02079 3.5e-80 2.7.7.65 T diguanylate cyclase activity
HKLHJAOF_02080 5.3e-202 ydaN S Bacterial cellulose synthase subunit
HKLHJAOF_02081 2.1e-182 ydaM M Glycosyl transferase family group 2
HKLHJAOF_02082 5.8e-81 S Protein conserved in bacteria
HKLHJAOF_02083 8.6e-74
HKLHJAOF_02084 2.1e-80 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HKLHJAOF_02085 5.3e-58 2.7.7.65 T diguanylate cyclase
HKLHJAOF_02086 5.7e-162 nox C NADH oxidase
HKLHJAOF_02087 3.7e-72 yliE T Putative diguanylate phosphodiesterase
HKLHJAOF_02088 4.3e-26
HKLHJAOF_02089 3.7e-67 K MarR family
HKLHJAOF_02090 4e-11 S response to antibiotic
HKLHJAOF_02091 1.2e-159 S Putative esterase
HKLHJAOF_02092 6.4e-183
HKLHJAOF_02093 3.5e-103 rmaB K Transcriptional regulator, MarR family
HKLHJAOF_02094 1.3e-84 F NUDIX domain
HKLHJAOF_02095 3.5e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKLHJAOF_02096 3.4e-29
HKLHJAOF_02097 4.4e-125 S zinc-ribbon domain
HKLHJAOF_02098 2e-197 pbpX1 V Beta-lactamase
HKLHJAOF_02099 1.5e-181 K AI-2E family transporter
HKLHJAOF_02100 1.1e-127 srtA 3.4.22.70 M Sortase family
HKLHJAOF_02101 1.5e-65 gtcA S Teichoic acid glycosylation protein
HKLHJAOF_02102 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKLHJAOF_02103 1.6e-168 gbuC E glycine betaine
HKLHJAOF_02104 1.8e-124 proW E glycine betaine
HKLHJAOF_02105 6.5e-221 gbuA 3.6.3.32 E glycine betaine
HKLHJAOF_02106 4.4e-132 sfsA S Belongs to the SfsA family
HKLHJAOF_02107 1.6e-66 usp1 T Universal stress protein family
HKLHJAOF_02108 1.8e-250 yxbA 6.3.1.12 S ATP-grasp enzyme
HKLHJAOF_02109 3.4e-155 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKLHJAOF_02110 1.4e-281 thrC 4.2.3.1 E Threonine synthase
HKLHJAOF_02111 1.3e-229 hom 1.1.1.3 E homoserine dehydrogenase
HKLHJAOF_02112 6.7e-251 yclM 2.7.2.4 E Belongs to the aspartokinase family
HKLHJAOF_02113 5.8e-166 yqiK S SPFH domain / Band 7 family
HKLHJAOF_02114 5.7e-68
HKLHJAOF_02115 1.5e-154 pfoS S Phosphotransferase system, EIIC
HKLHJAOF_02116 5.9e-180 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHJAOF_02117 4.2e-217 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HKLHJAOF_02118 6.2e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
HKLHJAOF_02119 6e-143 S Alpha/beta hydrolase family
HKLHJAOF_02120 2.3e-102 K Bacterial regulatory proteins, tetR family
HKLHJAOF_02121 1.2e-171 XK27_06930 V domain protein
HKLHJAOF_02122 2.1e-171 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKLHJAOF_02123 0.0 asnB 6.3.5.4 E Asparagine synthase
HKLHJAOF_02124 2.2e-08
HKLHJAOF_02125 5.2e-206 S Calcineurin-like phosphoesterase
HKLHJAOF_02126 1.5e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HKLHJAOF_02127 7.3e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKLHJAOF_02128 1.2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKLHJAOF_02129 8.8e-167 natA S ABC transporter
HKLHJAOF_02130 1.6e-209 ysdA CP ABC-2 family transporter protein
HKLHJAOF_02131 8.1e-64 K helix_turn_helix gluconate operon transcriptional repressor
HKLHJAOF_02132 4.9e-162 CcmA V ABC transporter
HKLHJAOF_02133 5.7e-115 VPA0052 I ABC-2 family transporter protein
HKLHJAOF_02134 5.8e-146 IQ reductase
HKLHJAOF_02135 9.3e-259 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLHJAOF_02136 0.0 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKLHJAOF_02137 1.7e-159 licT K CAT RNA binding domain
HKLHJAOF_02138 3.2e-284 cydC V ABC transporter transmembrane region
HKLHJAOF_02139 6.1e-310 cydD CO ABC transporter transmembrane region
HKLHJAOF_02140 1.7e-75 ynhH S NusG domain II
HKLHJAOF_02141 2.8e-170 M Peptidoglycan-binding domain 1 protein
HKLHJAOF_02143 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKLHJAOF_02144 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKLHJAOF_02145 6.5e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HKLHJAOF_02146 1.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
HKLHJAOF_02147 4.1e-237 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HKLHJAOF_02148 6.5e-174 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HKLHJAOF_02149 1.7e-37
HKLHJAOF_02150 4.9e-87
HKLHJAOF_02151 2.7e-24
HKLHJAOF_02152 5.2e-162 yicL EG EamA-like transporter family
HKLHJAOF_02153 1.9e-112 tag 3.2.2.20 L glycosylase
HKLHJAOF_02154 4.2e-77 usp5 T universal stress protein
HKLHJAOF_02155 4.7e-64 K Helix-turn-helix XRE-family like proteins
HKLHJAOF_02156 4.9e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
HKLHJAOF_02157 1.3e-223 queG 1.17.99.6 C Domain of unknown function (DUF1730)
HKLHJAOF_02158 4.1e-62
HKLHJAOF_02159 1.4e-87 bioY S BioY family
HKLHJAOF_02161 5.4e-102 Q methyltransferase
HKLHJAOF_02162 2.6e-98 T Sh3 type 3 domain protein
HKLHJAOF_02163 3.9e-113 yfeJ 6.3.5.2 F glutamine amidotransferase
HKLHJAOF_02164 8e-137 S Uncharacterized protein conserved in bacteria (DUF2263)
HKLHJAOF_02165 4.9e-257 yhdP S Transporter associated domain
HKLHJAOF_02166 7.2e-144 S Alpha beta hydrolase
HKLHJAOF_02167 3e-195 I Acyltransferase
HKLHJAOF_02168 3.1e-262 lmrB EGP Major facilitator Superfamily
HKLHJAOF_02169 8.8e-84 S Domain of unknown function (DUF4811)
HKLHJAOF_02170 4.2e-95 maf D nucleoside-triphosphate diphosphatase activity
HKLHJAOF_02171 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKLHJAOF_02172 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKLHJAOF_02173 0.0 ydaO E amino acid
HKLHJAOF_02174 1.1e-56 S Domain of unknown function (DUF1827)
HKLHJAOF_02175 4.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKLHJAOF_02176 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKLHJAOF_02177 7.2e-110 ydiL S CAAX protease self-immunity
HKLHJAOF_02178 3.7e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HKLHJAOF_02179 1.2e-183
HKLHJAOF_02180 9.7e-158 ytrB V ABC transporter
HKLHJAOF_02181 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HKLHJAOF_02182 4.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKLHJAOF_02183 0.0 uup S ABC transporter, ATP-binding protein
HKLHJAOF_02184 1.6e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_02185 1.8e-187 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKLHJAOF_02186 2.3e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HKLHJAOF_02187 5.3e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HKLHJAOF_02188 7e-119
HKLHJAOF_02189 7.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HKLHJAOF_02190 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
HKLHJAOF_02191 1.3e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
HKLHJAOF_02192 1.7e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKLHJAOF_02193 1.7e-57 yabA L Involved in initiation control of chromosome replication
HKLHJAOF_02194 1.3e-174 holB 2.7.7.7 L DNA polymerase III
HKLHJAOF_02195 7.8e-52 yaaQ S Cyclic-di-AMP receptor
HKLHJAOF_02196 2.2e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKLHJAOF_02197 8.7e-38 S Protein of unknown function (DUF2508)
HKLHJAOF_02198 5.6e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKLHJAOF_02199 1.5e-33 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKLHJAOF_02200 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKLHJAOF_02201 8.9e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKLHJAOF_02202 4.7e-49
HKLHJAOF_02203 3.4e-106 rsmC 2.1.1.172 J Methyltransferase
HKLHJAOF_02204 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKLHJAOF_02205 4.7e-70 tnpB L Putative transposase DNA-binding domain
HKLHJAOF_02206 1.4e-133 tnpB L Putative transposase DNA-binding domain
HKLHJAOF_02208 8.2e-67
HKLHJAOF_02209 3.3e-172 ccpB 5.1.1.1 K lacI family
HKLHJAOF_02210 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
HKLHJAOF_02211 1.7e-154 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKLHJAOF_02212 3.8e-55 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKLHJAOF_02213 7.7e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKLHJAOF_02214 3.2e-171 mdtG EGP Major facilitator Superfamily
HKLHJAOF_02215 5e-221 yceI G Sugar (and other) transporter
HKLHJAOF_02216 9.5e-23
HKLHJAOF_02217 1.2e-226
HKLHJAOF_02218 8.9e-289 2.4.1.52 GT4 M Glycosyl transferases group 1
HKLHJAOF_02219 3.3e-302 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HKLHJAOF_02220 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HKLHJAOF_02221 2.7e-94 yqaB S Acetyltransferase (GNAT) domain
HKLHJAOF_02222 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKLHJAOF_02223 4.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKLHJAOF_02224 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HKLHJAOF_02225 2.1e-266 nylA 3.5.1.4 J Belongs to the amidase family
HKLHJAOF_02226 2.4e-90 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
HKLHJAOF_02227 6.1e-86 S ECF transporter, substrate-specific component
HKLHJAOF_02228 3.1e-63 S Domain of unknown function (DUF4430)
HKLHJAOF_02229 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HKLHJAOF_02230 5.9e-79 F nucleoside 2-deoxyribosyltransferase
HKLHJAOF_02231 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
HKLHJAOF_02232 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
HKLHJAOF_02233 1.5e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKLHJAOF_02234 8.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKLHJAOF_02235 3.2e-170 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HKLHJAOF_02236 1.1e-164 menA 2.5.1.74 M UbiA prenyltransferase family
HKLHJAOF_02238 2e-194 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKLHJAOF_02239 2.6e-219 tnpB L Putative transposase DNA-binding domain
HKLHJAOF_02240 4.6e-139 cad S FMN_bind
HKLHJAOF_02241 8.2e-221 ndh 1.6.99.3 C NADH dehydrogenase
HKLHJAOF_02242 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_02243 2.6e-127 ndh 1.6.99.3 C NADH dehydrogenase
HKLHJAOF_02244 1.7e-81 ynhH S NusG domain II
HKLHJAOF_02245 5.2e-99 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HKLHJAOF_02246 4.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKLHJAOF_02247 2.7e-80
HKLHJAOF_02248 6.9e-147 T Calcineurin-like phosphoesterase superfamily domain
HKLHJAOF_02249 4.6e-97
HKLHJAOF_02250 2.6e-158
HKLHJAOF_02251 2.7e-152 V ATPases associated with a variety of cellular activities
HKLHJAOF_02252 7.1e-215
HKLHJAOF_02253 2.4e-193
HKLHJAOF_02254 2.5e-121 1.5.1.40 S Rossmann-like domain
HKLHJAOF_02255 6.1e-191 XK27_00915 C Luciferase-like monooxygenase
HKLHJAOF_02256 1.2e-97 yacP S YacP-like NYN domain
HKLHJAOF_02257 7e-144 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKLHJAOF_02258 2.1e-73 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKLHJAOF_02259 2.5e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKLHJAOF_02260 3.3e-245 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HKLHJAOF_02261 8.6e-99
HKLHJAOF_02263 3.3e-259 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKLHJAOF_02264 1e-140 yhfC S Putative membrane peptidase family (DUF2324)
HKLHJAOF_02265 1.8e-155 S Membrane
HKLHJAOF_02266 2.8e-61 K helix_turn_helix gluconate operon transcriptional repressor
HKLHJAOF_02267 2.9e-293 V ABC transporter transmembrane region
HKLHJAOF_02268 8.7e-106 inlJ M MucBP domain
HKLHJAOF_02269 9.6e-99 inlJ M MucBP domain
HKLHJAOF_02270 1.9e-69 S ABC-2 family transporter protein
HKLHJAOF_02271 3.1e-95 V ABC transporter, ATP-binding protein
HKLHJAOF_02272 1.4e-108 K sequence-specific DNA binding
HKLHJAOF_02273 1.8e-201 yacL S domain protein
HKLHJAOF_02274 8.5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKLHJAOF_02275 1.9e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
HKLHJAOF_02276 4.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HKLHJAOF_02277 2.7e-257 pepC 3.4.22.40 E aminopeptidase
HKLHJAOF_02278 3.8e-262 pepC 3.4.22.40 E Peptidase C1-like family
HKLHJAOF_02279 3.6e-194
HKLHJAOF_02280 1.9e-209 S ABC-2 family transporter protein
HKLHJAOF_02281 4.3e-166 V ATPases associated with a variety of cellular activities
HKLHJAOF_02282 0.0 kup P Transport of potassium into the cell
HKLHJAOF_02283 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
HKLHJAOF_02284 1.5e-92 ccpN K Domain in cystathionine beta-synthase and other proteins.
HKLHJAOF_02285 2.9e-122 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKLHJAOF_02286 4e-201 ltrA S Bacterial low temperature requirement A protein (LtrA)
HKLHJAOF_02287 7.2e-46
HKLHJAOF_02288 2.8e-194 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKLHJAOF_02289 8.8e-09 yhjA S CsbD-like
HKLHJAOF_02290 3.1e-151 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKLHJAOF_02291 9.2e-191 EGP Major facilitator Superfamily
HKLHJAOF_02292 8.5e-115 udp 2.4.2.3, 3.2.2.4 F Phosphorylase superfamily
HKLHJAOF_02293 7.3e-172 EGP Major facilitator Superfamily
HKLHJAOF_02294 5.3e-95 KT Purine catabolism regulatory protein-like family
HKLHJAOF_02295 5.4e-08
HKLHJAOF_02296 2.5e-32
HKLHJAOF_02297 1.1e-32
HKLHJAOF_02298 4.9e-224 pimH EGP Major facilitator Superfamily
HKLHJAOF_02299 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKLHJAOF_02300 3e-148 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKLHJAOF_02302 8.7e-93
HKLHJAOF_02303 9.8e-33 bacI V MacB-like periplasmic core domain
HKLHJAOF_02304 2.3e-55 macB V ABC transporter, ATP-binding protein
HKLHJAOF_02306 3.2e-128 3.4.22.70 M Sortase family
HKLHJAOF_02307 8.4e-290 M Cna protein B-type domain
HKLHJAOF_02308 5.1e-259 M domain protein
HKLHJAOF_02309 0.0 M domain protein
HKLHJAOF_02310 3.3e-103
HKLHJAOF_02311 4.3e-225 N Uncharacterized conserved protein (DUF2075)
HKLHJAOF_02312 1.8e-206 MA20_36090 S Protein of unknown function (DUF2974)
HKLHJAOF_02313 4.1e-97 K Helix-turn-helix XRE-family like proteins
HKLHJAOF_02314 1.4e-56 K Transcriptional regulator PadR-like family
HKLHJAOF_02315 7.1e-136
HKLHJAOF_02316 6.6e-134
HKLHJAOF_02317 9e-44 S Enterocin A Immunity
HKLHJAOF_02318 2.7e-186 tas C Aldo/keto reductase family
HKLHJAOF_02319 2.5e-253 yjjP S Putative threonine/serine exporter
HKLHJAOF_02320 7e-59
HKLHJAOF_02321 2.9e-225 mesE M Transport protein ComB
HKLHJAOF_02322 1e-279 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKLHJAOF_02323 2.6e-266 L Transposase DDE domain
HKLHJAOF_02324 3.3e-112 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKLHJAOF_02326 3.3e-218 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKLHJAOF_02327 7.3e-133 plnD K LytTr DNA-binding domain
HKLHJAOF_02328 1.9e-44 spiA S Enterocin A Immunity
HKLHJAOF_02329 5.8e-21
HKLHJAOF_02333 4.4e-133 S CAAX protease self-immunity
HKLHJAOF_02334 9.3e-69 K Transcriptional regulator
HKLHJAOF_02335 6.4e-252 EGP Major Facilitator Superfamily
HKLHJAOF_02336 2.4e-53
HKLHJAOF_02337 1.9e-53 S Enterocin A Immunity
HKLHJAOF_02338 1.7e-179 S Aldo keto reductase
HKLHJAOF_02339 7.1e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHJAOF_02340 4.5e-216 yqiG C Oxidoreductase
HKLHJAOF_02341 1.3e-16 S Short C-terminal domain
HKLHJAOF_02342 9.5e-253 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKLHJAOF_02343 2.1e-133
HKLHJAOF_02344 2e-17
HKLHJAOF_02345 5.3e-279 mntH P H( )-stimulated, divalent metal cation uptake system
HKLHJAOF_02346 0.0 pacL P P-type ATPase
HKLHJAOF_02347 9.8e-64
HKLHJAOF_02348 6.5e-227 EGP Major Facilitator Superfamily
HKLHJAOF_02349 2.1e-311 mco Q Multicopper oxidase
HKLHJAOF_02350 1e-24
HKLHJAOF_02351 1.7e-111 2.5.1.105 P Cation efflux family
HKLHJAOF_02352 8.7e-51 czrA K Transcriptional regulator, ArsR family
HKLHJAOF_02353 5.4e-175 sitA P Belongs to the bacterial solute-binding protein 9 family
HKLHJAOF_02354 9.5e-145 mtsB U ABC 3 transport family
HKLHJAOF_02355 1.9e-130 mntB 3.6.3.35 P ABC transporter
HKLHJAOF_02356 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKLHJAOF_02357 7.7e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
HKLHJAOF_02358 1.4e-118 GM NmrA-like family
HKLHJAOF_02359 4.9e-85
HKLHJAOF_02360 1.3e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
HKLHJAOF_02361 1.8e-19
HKLHJAOF_02363 3.4e-53 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKLHJAOF_02364 1.2e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKLHJAOF_02365 1.4e-286 G MFS/sugar transport protein
HKLHJAOF_02366 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase concanavalin-like domain
HKLHJAOF_02367 1.6e-169 ssuA P NMT1-like family
HKLHJAOF_02368 1.4e-292 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
HKLHJAOF_02369 3.4e-233 yfiQ I Acyltransferase family
HKLHJAOF_02370 1.3e-120 ssuB P ATPases associated with a variety of cellular activities
HKLHJAOF_02371 6e-146 ssuC U Binding-protein-dependent transport system inner membrane component
HKLHJAOF_02372 3.8e-122 S B3/4 domain
HKLHJAOF_02374 3.3e-29 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKLHJAOF_02375 8.6e-15
HKLHJAOF_02376 0.0 V ABC transporter
HKLHJAOF_02377 0.0 V ATPases associated with a variety of cellular activities
HKLHJAOF_02378 1.4e-207 EGP Transmembrane secretion effector
HKLHJAOF_02379 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HKLHJAOF_02380 7e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKLHJAOF_02381 4.8e-103 K Bacterial regulatory proteins, tetR family
HKLHJAOF_02382 9.4e-184 yxeA V FtsX-like permease family
HKLHJAOF_02383 1.3e-125 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
HKLHJAOF_02384 6.4e-34
HKLHJAOF_02385 2e-135 tipA K TipAS antibiotic-recognition domain
HKLHJAOF_02386 4.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKLHJAOF_02387 1.6e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLHJAOF_02388 3.2e-158 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLHJAOF_02389 1.8e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLHJAOF_02390 7.6e-115
HKLHJAOF_02391 3.1e-60 rplQ J Ribosomal protein L17
HKLHJAOF_02392 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLHJAOF_02393 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKLHJAOF_02394 2.1e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKLHJAOF_02395 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HKLHJAOF_02396 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKLHJAOF_02397 1.4e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKLHJAOF_02398 9.8e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKLHJAOF_02399 2.2e-62 rplO J Binds to the 23S rRNA
HKLHJAOF_02400 1.7e-24 rpmD J Ribosomal protein L30
HKLHJAOF_02401 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKLHJAOF_02402 4.6e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKLHJAOF_02403 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKLHJAOF_02404 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKLHJAOF_02405 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKLHJAOF_02406 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKLHJAOF_02407 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKLHJAOF_02408 1.4e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKLHJAOF_02409 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HKLHJAOF_02410 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKLHJAOF_02411 3.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKLHJAOF_02412 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKLHJAOF_02413 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKLHJAOF_02414 3.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKLHJAOF_02415 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKLHJAOF_02416 5.9e-109 rplD J Forms part of the polypeptide exit tunnel
HKLHJAOF_02417 3e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKLHJAOF_02418 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HKLHJAOF_02419 1.2e-68 psiE S Phosphate-starvation-inducible E
HKLHJAOF_02420 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HKLHJAOF_02421 5.5e-197 yfjR K WYL domain
HKLHJAOF_02422 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKLHJAOF_02423 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKLHJAOF_02424 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKLHJAOF_02425 0.0 M domain protein
HKLHJAOF_02426 6.1e-38 M domain protein
HKLHJAOF_02427 2.6e-83 3.4.23.43
HKLHJAOF_02428 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLHJAOF_02429 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLHJAOF_02430 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKLHJAOF_02431 3.6e-79 ctsR K Belongs to the CtsR family
HKLHJAOF_02440 6.8e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HKLHJAOF_02441 2.4e-71 S COG NOG38524 non supervised orthologous group
HKLHJAOF_02444 6.1e-35
HKLHJAOF_02445 5.6e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HKLHJAOF_02446 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKLHJAOF_02447 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKLHJAOF_02448 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKLHJAOF_02449 5.9e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKLHJAOF_02450 2.1e-241 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKLHJAOF_02451 5.2e-81 yabR J RNA binding
HKLHJAOF_02452 4.4e-65 divIC D cell cycle
HKLHJAOF_02453 1.8e-38 yabO J S4 domain protein
HKLHJAOF_02454 1.6e-280 yabM S Polysaccharide biosynthesis protein
HKLHJAOF_02455 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKLHJAOF_02456 2.1e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKLHJAOF_02457 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKLHJAOF_02458 5.9e-263 S Putative peptidoglycan binding domain
HKLHJAOF_02459 2.9e-96 padR K Transcriptional regulator PadR-like family
HKLHJAOF_02460 1.1e-238 XK27_06930 S ABC-2 family transporter protein
HKLHJAOF_02461 3.4e-114 1.6.5.2 S Flavodoxin-like fold
HKLHJAOF_02462 5.1e-119 S (CBS) domain
HKLHJAOF_02463 1.8e-130 yciB M ErfK YbiS YcfS YnhG
HKLHJAOF_02464 4e-278 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HKLHJAOF_02465 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
HKLHJAOF_02466 1.2e-86 S QueT transporter
HKLHJAOF_02467 1.4e-12
HKLHJAOF_02468 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
HKLHJAOF_02469 2.4e-37
HKLHJAOF_02470 1.6e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKLHJAOF_02471 1.7e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKLHJAOF_02472 4.5e-264 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKLHJAOF_02473 5.6e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKLHJAOF_02474 3.3e-146
HKLHJAOF_02475 1.9e-123 S Tetratricopeptide repeat
HKLHJAOF_02476 1.7e-122
HKLHJAOF_02477 1.4e-72
HKLHJAOF_02478 3.3e-42 rpmE2 J Ribosomal protein L31
HKLHJAOF_02479 2.8e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKLHJAOF_02481 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKLHJAOF_02482 5.9e-219 ndh 1.6.99.3 C NADH dehydrogenase
HKLHJAOF_02485 7.9e-152 S Protein of unknown function (DUF1211)
HKLHJAOF_02486 5.9e-62 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKLHJAOF_02487 3.5e-79 ywiB S Domain of unknown function (DUF1934)
HKLHJAOF_02488 6.7e-156 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HKLHJAOF_02489 7.4e-266 ywfO S HD domain protein
HKLHJAOF_02490 2.4e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
HKLHJAOF_02491 5.9e-178 S DUF218 domain
HKLHJAOF_02492 1.8e-60 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKLHJAOF_02493 1.6e-73
HKLHJAOF_02494 8.6e-51 nudA S ASCH
HKLHJAOF_02495 1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKLHJAOF_02496 2.8e-212 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKLHJAOF_02497 3.5e-219 ysaA V RDD family
HKLHJAOF_02498 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HKLHJAOF_02499 6.5e-119 ybbL S ABC transporter, ATP-binding protein
HKLHJAOF_02500 3.3e-122 ybbM S Uncharacterised protein family (UPF0014)
HKLHJAOF_02501 6.7e-159 czcD P cation diffusion facilitator family transporter
HKLHJAOF_02502 5.8e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKLHJAOF_02503 1.1e-37 veg S Biofilm formation stimulator VEG
HKLHJAOF_02504 1.4e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKLHJAOF_02505 1.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKLHJAOF_02506 1.3e-145 tatD L hydrolase, TatD family
HKLHJAOF_02507 7.7e-80 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HKLHJAOF_02508 9.5e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HKLHJAOF_02509 6.9e-172 yqhA G Aldose 1-epimerase
HKLHJAOF_02510 3e-125 T LytTr DNA-binding domain
HKLHJAOF_02511 4.5e-166 2.7.13.3 T GHKL domain
HKLHJAOF_02512 0.0 V ABC transporter
HKLHJAOF_02513 0.0 V ABC transporter
HKLHJAOF_02514 4.1e-30 K Transcriptional
HKLHJAOF_02515 2.2e-65
HKLHJAOF_02516 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKLHJAOF_02517 1e-171 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HKLHJAOF_02518 1.2e-146 yunF F Protein of unknown function DUF72
HKLHJAOF_02519 1.1e-91 3.6.1.55 F NUDIX domain
HKLHJAOF_02520 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HKLHJAOF_02521 5.3e-107 yiiE S Protein of unknown function (DUF1211)
HKLHJAOF_02522 2.2e-128 cobB K Sir2 family
HKLHJAOF_02523 1.2e-07
HKLHJAOF_02524 5.7e-169
HKLHJAOF_02525 1.9e-97 yxkA S Phosphatidylethanolamine-binding protein
HKLHJAOF_02527 4.2e-162 ypuA S Protein of unknown function (DUF1002)
HKLHJAOF_02528 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKLHJAOF_02529 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKLHJAOF_02530 2.8e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKLHJAOF_02531 3e-173 S Aldo keto reductase
HKLHJAOF_02532 9.3e-155 bioC 2.1.1.187, 2.1.1.197 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HKLHJAOF_02533 1.7e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HKLHJAOF_02534 1e-238 dinF V MatE
HKLHJAOF_02535 1.2e-109 S TPM domain
HKLHJAOF_02536 3.1e-102 lemA S LemA family
HKLHJAOF_02537 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKLHJAOF_02538 1.2e-73 EGP Major Facilitator Superfamily
HKLHJAOF_02539 5e-251 gshR 1.8.1.7 C Glutathione reductase
HKLHJAOF_02540 1.7e-176 proV E ABC transporter, ATP-binding protein
HKLHJAOF_02541 8.9e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKLHJAOF_02542 0.0 helD 3.6.4.12 L DNA helicase
HKLHJAOF_02543 1.5e-147 rlrG K Transcriptional regulator
HKLHJAOF_02544 1.1e-175 shetA P Voltage-dependent anion channel
HKLHJAOF_02545 1.5e-135 nodJ V ABC-2 type transporter
HKLHJAOF_02546 3.2e-133 nodI V ABC transporter
HKLHJAOF_02547 6.8e-130 ydfF K Transcriptional
HKLHJAOF_02548 1.2e-109 S CAAX protease self-immunity
HKLHJAOF_02550 1.7e-277 V ABC transporter transmembrane region
HKLHJAOF_02551 6.7e-108 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKLHJAOF_02552 7.2e-71 K MarR family
HKLHJAOF_02553 0.0 uvrA3 L excinuclease ABC
HKLHJAOF_02554 1.4e-192 yghZ C Aldo keto reductase family protein
HKLHJAOF_02555 2.4e-142 S hydrolase
HKLHJAOF_02556 1.2e-58
HKLHJAOF_02557 4.8e-12
HKLHJAOF_02558 3.6e-115 yoaK S Protein of unknown function (DUF1275)
HKLHJAOF_02559 2.4e-127 yjhF G Phosphoglycerate mutase family
HKLHJAOF_02560 8.1e-151 yitU 3.1.3.104 S hydrolase
HKLHJAOF_02561 3.6e-90 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKLHJAOF_02562 5.8e-166 K LysR substrate binding domain
HKLHJAOF_02563 1.3e-226 EK Aminotransferase, class I
HKLHJAOF_02565 2.9e-45
HKLHJAOF_02566 9.4e-58
HKLHJAOF_02567 5.6e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKLHJAOF_02568 7.3e-116 ydfK S Protein of unknown function (DUF554)
HKLHJAOF_02569 2.2e-87
HKLHJAOF_02571 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_02572 1.3e-168 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HKLHJAOF_02573 1.5e-130 rpl K Helix-turn-helix domain, rpiR family
HKLHJAOF_02574 2.8e-298 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKLHJAOF_02575 5.7e-288 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HKLHJAOF_02576 3.2e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKLHJAOF_02577 5.6e-245 P Sodium:sulfate symporter transmembrane region
HKLHJAOF_02578 5.8e-158 K LysR substrate binding domain
HKLHJAOF_02579 1.3e-75
HKLHJAOF_02580 9e-72 K Transcriptional regulator
HKLHJAOF_02581 1.5e-245 ypiB EGP Major facilitator Superfamily
HKLHJAOF_02582 7.8e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HKLHJAOF_02584 4.3e-241 pts36C G PTS system sugar-specific permease component
HKLHJAOF_02585 1.1e-50 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_02586 3e-68 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_02587 1.2e-119 K DeoR C terminal sensor domain
HKLHJAOF_02589 4.4e-166 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HKLHJAOF_02590 9.1e-258 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HKLHJAOF_02591 3.8e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HKLHJAOF_02592 4.5e-285 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HKLHJAOF_02593 8.8e-227 iolF EGP Major facilitator Superfamily
HKLHJAOF_02594 4.1e-192 rhaR K helix_turn_helix, arabinose operon control protein
HKLHJAOF_02595 6.4e-215 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HKLHJAOF_02596 1.4e-65 S Protein of unknown function (DUF1093)
HKLHJAOF_02597 1.3e-120
HKLHJAOF_02598 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HKLHJAOF_02599 4.6e-305 plyA3 M Right handed beta helix region
HKLHJAOF_02600 2.9e-81
HKLHJAOF_02601 1.2e-269 M Heparinase II/III N-terminus
HKLHJAOF_02603 3.5e-66 G PTS system fructose IIA component
HKLHJAOF_02604 3.6e-143 agaD G PTS system mannose/fructose/sorbose family IID component
HKLHJAOF_02605 6.4e-132 G PTS system sorbose-specific iic component
HKLHJAOF_02606 3.5e-80 agaV 2.7.1.191 G PTS system sorbose subfamily IIB component
HKLHJAOF_02607 8.3e-205 ugl 3.2.1.180 GH88 S Glycosyl Hydrolase Family 88
HKLHJAOF_02608 8.4e-103 Z012_03480 S Psort location Cytoplasmic, score
HKLHJAOF_02609 1.9e-109 K Bacterial transcriptional regulator
HKLHJAOF_02610 1.7e-143 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HKLHJAOF_02611 1e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKLHJAOF_02612 2.3e-87 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HKLHJAOF_02613 1.8e-152 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HKLHJAOF_02614 8.7e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKLHJAOF_02615 0.0 CP_0954 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
HKLHJAOF_02616 5.8e-198 rafA 3.2.1.22 G Melibiase
HKLHJAOF_02617 2.6e-266 L Transposase DDE domain
HKLHJAOF_02618 2.7e-40 2.7.1.191 G PTS system sorbose subfamily IIB component
HKLHJAOF_02619 3.1e-65 G PTS system mannose/fructose/sorbose family IID component
HKLHJAOF_02620 4.4e-64 G PTS system sorbose-specific iic component
HKLHJAOF_02621 2.7e-22 2.7.1.191 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HKLHJAOF_02622 4.6e-53 araR K Transcriptional regulator
HKLHJAOF_02623 7.8e-271 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HKLHJAOF_02624 3.6e-296 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HKLHJAOF_02625 8.3e-208 V ABC-type multidrug transport system, ATPase and permease components
HKLHJAOF_02626 6.9e-108 K Transcriptional activator, Rgg GadR MutR family
HKLHJAOF_02627 7e-125 K Helix-turn-helix domain, rpiR family
HKLHJAOF_02628 5.2e-60 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKLHJAOF_02629 2e-09 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKLHJAOF_02631 3.7e-137 4.1.2.14 S KDGP aldolase
HKLHJAOF_02632 1.2e-202 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
HKLHJAOF_02633 2.2e-215 dho 3.5.2.3 S Amidohydrolase family
HKLHJAOF_02634 1e-106 S Domain of unknown function (DUF4310)
HKLHJAOF_02635 1.7e-137 S Domain of unknown function (DUF4311)
HKLHJAOF_02636 1.7e-52 S Domain of unknown function (DUF4312)
HKLHJAOF_02637 1.2e-61 S Glycine-rich SFCGS
HKLHJAOF_02638 1.5e-53 S PRD domain
HKLHJAOF_02639 0.0 K Mga helix-turn-helix domain
HKLHJAOF_02640 2.9e-122 tal 2.2.1.2 H Pfam:Transaldolase
HKLHJAOF_02641 3.9e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HKLHJAOF_02642 1.6e-194 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HKLHJAOF_02643 2.2e-102 srlA G PTS system enzyme II sorbitol-specific factor
HKLHJAOF_02644 1.4e-87 gutM K Glucitol operon activator protein (GutM)
HKLHJAOF_02645 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HKLHJAOF_02646 2.5e-144 IQ NAD dependent epimerase/dehydratase family
HKLHJAOF_02647 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_02648 2.5e-24 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HKLHJAOF_02649 1.5e-29 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
HKLHJAOF_02650 1.6e-137 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKLHJAOF_02651 5.3e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HKLHJAOF_02652 5.4e-167 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HKLHJAOF_02653 4.9e-137 repA K DeoR C terminal sensor domain
HKLHJAOF_02654 1.6e-114 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HKLHJAOF_02655 1.4e-44 sgaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_02656 4.5e-280 ulaA S PTS system sugar-specific permease component
HKLHJAOF_02657 3.6e-79 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHJAOF_02658 1.2e-213 ulaG S Beta-lactamase superfamily domain
HKLHJAOF_02659 0.0 O Belongs to the peptidase S8 family
HKLHJAOF_02660 2.6e-42
HKLHJAOF_02661 1.6e-155 bglK_1 GK ROK family
HKLHJAOF_02662 9.8e-180 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HKLHJAOF_02663 4.1e-245 3.5.1.18 E Peptidase family M20/M25/M40
HKLHJAOF_02664 1.2e-129 ymfC K UTRA
HKLHJAOF_02665 5.3e-215 uhpT EGP Major facilitator Superfamily
HKLHJAOF_02666 4.7e-204 3.2.1.51 GH29 G Alpha-L-fucosidase
HKLHJAOF_02667 7.6e-91 yjgM K Acetyltransferase (GNAT) domain
HKLHJAOF_02668 3.7e-111 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HKLHJAOF_02670 2.8e-97 K Helix-turn-helix domain
HKLHJAOF_02671 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
HKLHJAOF_02672 9.6e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
HKLHJAOF_02673 9.9e-108 pncA Q Isochorismatase family
HKLHJAOF_02674 1.8e-262 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKLHJAOF_02675 3.6e-131 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKLHJAOF_02676 3.3e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKLHJAOF_02677 6.4e-241 ugpB G Bacterial extracellular solute-binding protein
HKLHJAOF_02678 2.2e-148 ugpE G ABC transporter permease
HKLHJAOF_02679 4.7e-163 ugpA P ABC-type sugar transport systems, permease components
HKLHJAOF_02680 9.5e-211 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HKLHJAOF_02681 5.1e-224 EGP Major facilitator Superfamily
HKLHJAOF_02682 1.5e-146 3.5.2.6 V Beta-lactamase enzyme family
HKLHJAOF_02683 4.5e-191 blaA6 V Beta-lactamase
HKLHJAOF_02684 2.9e-146 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKLHJAOF_02685 6.9e-162 ybbH_2 K Helix-turn-helix domain, rpiR family
HKLHJAOF_02686 7.6e-80 2.7.1.191 G PTS system sorbose subfamily IIB component
HKLHJAOF_02687 2.4e-150 G PTS system mannose/fructose/sorbose family IID component
HKLHJAOF_02688 1.8e-129 G PTS system sorbose-specific iic component
HKLHJAOF_02690 2.7e-202 S endonuclease exonuclease phosphatase family protein
HKLHJAOF_02691 1.5e-172 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HKLHJAOF_02692 8.5e-159 1.1.1.346 S reductase
HKLHJAOF_02693 2.5e-74 adhR K helix_turn_helix, mercury resistance
HKLHJAOF_02694 3.7e-142 Q Methyltransferase
HKLHJAOF_02695 9.1e-50 sugE U Multidrug resistance protein
HKLHJAOF_02697 1.2e-145 V ABC transporter transmembrane region
HKLHJAOF_02698 2.8e-57
HKLHJAOF_02699 5.9e-36
HKLHJAOF_02700 6.5e-108 S alpha beta
HKLHJAOF_02701 6.6e-79 MA20_25245 K FR47-like protein
HKLHJAOF_02702 1.7e-77 hisB 2.7.7.71, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 5.3.1.28, 6.3.2.10 GT9 E HAD-hyrolase-like
HKLHJAOF_02703 2.7e-132 wzb 3.1.3.48 T Tyrosine phosphatase family
HKLHJAOF_02704 3.5e-85 K Acetyltransferase (GNAT) domain
HKLHJAOF_02705 1.3e-122
HKLHJAOF_02706 1.2e-66 6.3.3.2 S ASCH
HKLHJAOF_02707 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKLHJAOF_02708 4.1e-198 ybiR P Citrate transporter
HKLHJAOF_02709 6.8e-100
HKLHJAOF_02710 7.3e-250 E Peptidase dimerisation domain
HKLHJAOF_02711 2.5e-297 E ABC transporter, substratebinding protein
HKLHJAOF_02712 1.3e-133
HKLHJAOF_02713 0.0 K helix_turn_helix, arabinose operon control protein
HKLHJAOF_02714 3.9e-282 G MFS/sugar transport protein
HKLHJAOF_02715 0.0 S Glycosyl hydrolase family 115
HKLHJAOF_02716 0.0 cadA P P-type ATPase
HKLHJAOF_02717 2.7e-76 hsp3 O Hsp20/alpha crystallin family
HKLHJAOF_02718 5.9e-70 S Iron-sulphur cluster biosynthesis
HKLHJAOF_02719 2.9e-206 htrA 3.4.21.107 O serine protease
HKLHJAOF_02720 2.7e-154 vicX 3.1.26.11 S domain protein
HKLHJAOF_02721 4.4e-141 yycI S YycH protein
HKLHJAOF_02722 5.3e-259 yycH S YycH protein
HKLHJAOF_02723 0.0 vicK 2.7.13.3 T Histidine kinase
HKLHJAOF_02724 8.1e-131 K response regulator
HKLHJAOF_02725 2.7e-123 S Alpha/beta hydrolase family
HKLHJAOF_02726 9.3e-259 arpJ P ABC transporter permease
HKLHJAOF_02727 8.8e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKLHJAOF_02728 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
HKLHJAOF_02729 7e-214 S Bacterial protein of unknown function (DUF871)
HKLHJAOF_02730 1.2e-73 S Domain of unknown function (DUF3284)
HKLHJAOF_02731 3.8e-238 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHJAOF_02732 6.9e-130 K UbiC transcription regulator-associated domain protein
HKLHJAOF_02733 3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_02734 4.9e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HKLHJAOF_02735 1.7e-107 speG J Acetyltransferase (GNAT) domain
HKLHJAOF_02736 2.2e-81 F NUDIX domain
HKLHJAOF_02737 2.5e-89 S AAA domain
HKLHJAOF_02738 2.3e-113 ycaC Q Isochorismatase family
HKLHJAOF_02739 6.8e-254 ydiC1 EGP Major Facilitator Superfamily
HKLHJAOF_02740 8.3e-213 yeaN P Transporter, major facilitator family protein
HKLHJAOF_02741 5e-173 iolS C Aldo keto reductase
HKLHJAOF_02742 4.4e-64 manO S Domain of unknown function (DUF956)
HKLHJAOF_02743 8.7e-170 manN G system, mannose fructose sorbose family IID component
HKLHJAOF_02744 1.6e-122 manY G PTS system
HKLHJAOF_02745 1.3e-182 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HKLHJAOF_02746 2.9e-219 EGP Major facilitator Superfamily
HKLHJAOF_02747 1e-187 K Helix-turn-helix XRE-family like proteins
HKLHJAOF_02748 2.3e-148 K Helix-turn-helix XRE-family like proteins
HKLHJAOF_02749 9.6e-158 K sequence-specific DNA binding
HKLHJAOF_02754 0.0 ybfG M peptidoglycan-binding domain-containing protein
HKLHJAOF_02755 4e-287 glnP P ABC transporter permease
HKLHJAOF_02756 2.4e-133 glnQ E ABC transporter, ATP-binding protein
HKLHJAOF_02757 1.7e-39
HKLHJAOF_02758 2e-236 malE G Bacterial extracellular solute-binding protein
HKLHJAOF_02759 9.1e-16
HKLHJAOF_02760 4.8e-131 S Protein of unknown function (DUF975)
HKLHJAOF_02761 1.5e-58 yqkB S Iron-sulphur cluster biosynthesis
HKLHJAOF_02762 1.2e-52
HKLHJAOF_02763 1.9e-80 S Bacterial PH domain
HKLHJAOF_02764 1.4e-284 ydbT S Bacterial PH domain
HKLHJAOF_02765 3.8e-142 S AAA ATPase domain
HKLHJAOF_02766 4.3e-166 yniA G Phosphotransferase enzyme family
HKLHJAOF_02767 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKLHJAOF_02768 2.1e-255 glnP P ABC transporter
HKLHJAOF_02769 3.3e-264 glnP P ABC transporter
HKLHJAOF_02770 8.3e-99 ydaF J Acetyltransferase (GNAT) domain
HKLHJAOF_02771 9.7e-104 S Stage II sporulation protein M
HKLHJAOF_02772 1.9e-167 yeaC S ATPase family associated with various cellular activities (AAA)
HKLHJAOF_02773 7.1e-133 yeaD S Protein of unknown function DUF58
HKLHJAOF_02774 0.0 yebA E Transglutaminase/protease-like homologues
HKLHJAOF_02775 7e-214 lsgC M Glycosyl transferases group 1
HKLHJAOF_02776 4.6e-255 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HKLHJAOF_02777 1.1e-192 L Transposase and inactivated derivatives, IS30 family
HKLHJAOF_02780 6.3e-197 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HKLHJAOF_02781 2.9e-222 maeN C 2-hydroxycarboxylate transporter family
HKLHJAOF_02782 1.8e-268 dcuS 2.7.13.3 T Single cache domain 3
HKLHJAOF_02783 4.1e-119 dpiA KT cheY-homologous receiver domain
HKLHJAOF_02784 5.5e-95
HKLHJAOF_02785 3.7e-118 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHJAOF_02787 1.8e-148 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
HKLHJAOF_02788 1.4e-68
HKLHJAOF_02789 1.6e-131 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
HKLHJAOF_02790 5.8e-169 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKLHJAOF_02792 8.8e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKLHJAOF_02793 1.5e-180 D Alpha beta
HKLHJAOF_02794 2.2e-184 lipA I Carboxylesterase family
HKLHJAOF_02795 3.5e-216 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HKLHJAOF_02796 1e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHJAOF_02797 0.0 mtlR K Mga helix-turn-helix domain
HKLHJAOF_02798 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HKLHJAOF_02799 2.8e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKLHJAOF_02800 3.3e-149 S haloacid dehalogenase-like hydrolase
HKLHJAOF_02801 2.8e-44
HKLHJAOF_02802 2e-14
HKLHJAOF_02803 4.1e-136
HKLHJAOF_02804 4.4e-222 spiA K IrrE N-terminal-like domain
HKLHJAOF_02805 5.6e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKLHJAOF_02806 2e-126 V ABC transporter
HKLHJAOF_02807 8.1e-208 bacI V MacB-like periplasmic core domain
HKLHJAOF_02808 1.1e-90 1.6.5.5 C nadph quinone reductase
HKLHJAOF_02809 3.6e-74 K Helix-turn-helix XRE-family like proteins
HKLHJAOF_02810 6.4e-30
HKLHJAOF_02811 1.1e-180
HKLHJAOF_02812 0.0 M Leucine rich repeats (6 copies)
HKLHJAOF_02813 2.1e-231 M Leucine rich repeats (6 copies)
HKLHJAOF_02814 6.7e-223 mtnE 2.6.1.83 E Aminotransferase
HKLHJAOF_02815 1.4e-139 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HKLHJAOF_02816 2.7e-149 M NLPA lipoprotein
HKLHJAOF_02819 2.8e-60 K Psort location Cytoplasmic, score
HKLHJAOF_02820 3.4e-197 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
HKLHJAOF_02823 2e-222 amd 3.5.1.47 E Peptidase family M20/M25/M40
HKLHJAOF_02824 2.6e-80 S Threonine/Serine exporter, ThrE
HKLHJAOF_02825 3.2e-133 thrE S Putative threonine/serine exporter
HKLHJAOF_02827 7.2e-30
HKLHJAOF_02828 2.3e-274 V ABC transporter transmembrane region
HKLHJAOF_02829 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKLHJAOF_02830 3.6e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKLHJAOF_02831 1.3e-137 jag S R3H domain protein
HKLHJAOF_02832 6.4e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKLHJAOF_02833 1.9e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKLHJAOF_02836 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)