ORF_ID e_value Gene_name EC_number CAZy COGs Description
HOFLKGFK_00001 4.8e-82 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HOFLKGFK_00002 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HOFLKGFK_00003 9.3e-57 3.4.23.43 S Type IV leader peptidase family
HOFLKGFK_00004 1.7e-180 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HOFLKGFK_00005 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOFLKGFK_00006 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOFLKGFK_00007 2.5e-36
HOFLKGFK_00008 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HOFLKGFK_00009 5.6e-129 pgm3 G Phosphoglycerate mutase family
HOFLKGFK_00010 4.5e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HOFLKGFK_00011 2.8e-94 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HOFLKGFK_00012 7e-150 lolD V ABC transporter
HOFLKGFK_00013 3.2e-212 V FtsX-like permease family
HOFLKGFK_00014 1.7e-61 S Domain of unknown function (DUF4418)
HOFLKGFK_00015 0.0 pcrA 3.6.4.12 L DNA helicase
HOFLKGFK_00016 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HOFLKGFK_00017 2.8e-244 pbuX F Permease family
HOFLKGFK_00018 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
HOFLKGFK_00019 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOFLKGFK_00020 2.7e-302 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HOFLKGFK_00021 1.2e-182 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HOFLKGFK_00022 1.1e-236 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HOFLKGFK_00023 1.5e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HOFLKGFK_00024 3e-251 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HOFLKGFK_00026 4.1e-212 ykiI
HOFLKGFK_00027 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HOFLKGFK_00028 1.9e-121 3.6.1.13 L NUDIX domain
HOFLKGFK_00029 3.8e-34 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HOFLKGFK_00030 5.5e-118 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HOFLKGFK_00031 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOFLKGFK_00032 9.4e-101 pdtaR T Response regulator receiver domain protein
HOFLKGFK_00033 6.6e-167 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
HOFLKGFK_00034 1.3e-187 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
HOFLKGFK_00036 1.1e-272 pyk 2.7.1.40 G Pyruvate kinase
HOFLKGFK_00037 8.8e-176 terC P Integral membrane protein, TerC family
HOFLKGFK_00038 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HOFLKGFK_00039 2.9e-114 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HOFLKGFK_00040 8.3e-255 rpsA J Ribosomal protein S1
HOFLKGFK_00041 1.9e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HOFLKGFK_00042 5.9e-173 P Zinc-uptake complex component A periplasmic
HOFLKGFK_00043 2e-160 znuC P ATPases associated with a variety of cellular activities
HOFLKGFK_00044 1e-140 znuB U ABC 3 transport family
HOFLKGFK_00045 9.8e-71 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HOFLKGFK_00046 3e-102 carD K CarD-like/TRCF domain
HOFLKGFK_00047 1.6e-146 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HOFLKGFK_00048 5.5e-307 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HOFLKGFK_00049 1.1e-187 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HOFLKGFK_00050 5e-139 ctsW S Phosphoribosyl transferase domain
HOFLKGFK_00051 1.1e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
HOFLKGFK_00052 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HOFLKGFK_00053 6.7e-102
HOFLKGFK_00054 6.4e-102
HOFLKGFK_00055 0.0 S Glycosyl transferase, family 2
HOFLKGFK_00056 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HOFLKGFK_00057 8.6e-217 K Cell envelope-related transcriptional attenuator domain
HOFLKGFK_00059 5.3e-170 K Cell envelope-related transcriptional attenuator domain
HOFLKGFK_00060 0.0 D FtsK/SpoIIIE family
HOFLKGFK_00061 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HOFLKGFK_00062 6e-277 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HOFLKGFK_00063 9.8e-142 yplQ S Haemolysin-III related
HOFLKGFK_00064 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOFLKGFK_00065 2.6e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HOFLKGFK_00066 4.6e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HOFLKGFK_00067 2.5e-90
HOFLKGFK_00068 1.9e-71 P Major Facilitator Superfamily
HOFLKGFK_00070 2.9e-182 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HOFLKGFK_00071 2e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HOFLKGFK_00072 6.5e-59 divIC D Septum formation initiator
HOFLKGFK_00073 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOFLKGFK_00074 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOFLKGFK_00075 1.9e-159 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOFLKGFK_00076 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HOFLKGFK_00077 3.6e-99 2.3.1.183 M Acetyltransferase (GNAT) domain
HOFLKGFK_00078 2.8e-151 S Uncharacterised protein family (UPF0182)
HOFLKGFK_00079 3.4e-261 S Uncharacterised protein family (UPF0182)
HOFLKGFK_00080 2.1e-31 S Uncharacterised protein family (UPF0182)
HOFLKGFK_00081 1.3e-74 S Uncharacterised protein family (UPF0182)
HOFLKGFK_00082 4e-178 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
HOFLKGFK_00083 6.2e-40 ybdD S Selenoprotein, putative
HOFLKGFK_00084 5.8e-62 cstA T 5TM C-terminal transporter carbon starvation CstA
HOFLKGFK_00085 1.9e-77 cstA T 5TM C-terminal transporter carbon starvation CstA
HOFLKGFK_00086 4.2e-270 cstA T 5TM C-terminal transporter carbon starvation CstA
HOFLKGFK_00087 1e-51 azlD E Branched-chain amino acid transport protein (AzlD)
HOFLKGFK_00088 4.7e-88 azlC E AzlC protein
HOFLKGFK_00089 1.7e-13 azlC E AzlC protein
HOFLKGFK_00090 5.4e-16 azlC E AzlC protein
HOFLKGFK_00091 1.3e-87 M Protein of unknown function (DUF3737)
HOFLKGFK_00092 1.8e-81 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HOFLKGFK_00093 7.1e-144 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HOFLKGFK_00094 2.6e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
HOFLKGFK_00095 3.6e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HOFLKGFK_00096 3.1e-236 patB 4.4.1.8 E Aminotransferase, class I II
HOFLKGFK_00097 5.3e-147 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HOFLKGFK_00098 5.8e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOFLKGFK_00099 0.0 lysX S Uncharacterised conserved protein (DUF2156)
HOFLKGFK_00100 1.6e-242 S Putative esterase
HOFLKGFK_00101 3.2e-142 ybbL V ATPases associated with a variety of cellular activities
HOFLKGFK_00102 5.1e-134 ybbM V Uncharacterised protein family (UPF0014)
HOFLKGFK_00103 4.4e-278 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HOFLKGFK_00104 2.1e-126 S Enoyl-(Acyl carrier protein) reductase
HOFLKGFK_00105 1.1e-226 rutG F Permease family
HOFLKGFK_00106 5.8e-157 3.1.3.73 G Phosphoglycerate mutase family
HOFLKGFK_00107 1.1e-138 K helix_turn_helix, arabinose operon control protein
HOFLKGFK_00108 1.9e-43 S Sulfite exporter TauE/SafE
HOFLKGFK_00109 4.3e-62 S Sulfite exporter TauE/SafE
HOFLKGFK_00110 1.9e-93 S ECF transporter, substrate-specific component
HOFLKGFK_00111 7.1e-112 2.7.1.48 F uridine kinase
HOFLKGFK_00112 2.5e-172 korD 1.2.7.3 C Domain of unknown function (DUF362)
HOFLKGFK_00113 2.5e-223 C Na H antiporter family protein
HOFLKGFK_00114 2.2e-180 MA20_14895 S Conserved hypothetical protein 698
HOFLKGFK_00115 7e-118
HOFLKGFK_00116 3.7e-16 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HOFLKGFK_00117 8e-88 cysB 4.2.1.22 EGP Major facilitator Superfamily
HOFLKGFK_00118 6.5e-241 cysB 4.2.1.22 EGP Major facilitator Superfamily
HOFLKGFK_00119 5e-11
HOFLKGFK_00120 8e-58 yccF S Inner membrane component domain
HOFLKGFK_00121 1.2e-118 K Bacterial regulatory proteins, tetR family
HOFLKGFK_00122 3e-213 G Transmembrane secretion effector
HOFLKGFK_00123 1.6e-16 K addiction module antidote protein HigA
HOFLKGFK_00124 5.5e-239 S HipA-like C-terminal domain
HOFLKGFK_00125 3.9e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HOFLKGFK_00126 1.3e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOFLKGFK_00127 2.3e-267 pip 3.4.11.5 S alpha/beta hydrolase fold
HOFLKGFK_00128 0.0 tcsS2 T Histidine kinase
HOFLKGFK_00129 1.7e-126 K helix_turn_helix, Lux Regulon
HOFLKGFK_00130 0.0 MV MacB-like periplasmic core domain
HOFLKGFK_00131 2.8e-140 V ABC transporter, ATP-binding protein
HOFLKGFK_00132 2.4e-192 K helix_turn_helix ASNC type
HOFLKGFK_00133 9.2e-22 P Cobalt transport protein
HOFLKGFK_00134 2.4e-95 P Cobalt transport protein
HOFLKGFK_00135 1.4e-110 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
HOFLKGFK_00136 1.5e-52 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
HOFLKGFK_00137 1.7e-94 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
HOFLKGFK_00138 2.2e-90 XK27_01265 S ECF-type riboflavin transporter, S component
HOFLKGFK_00139 1.8e-27 metY 2.5.1.49 E Aminotransferase class-V
HOFLKGFK_00140 2.2e-186 metY 2.5.1.49 E Aminotransferase class-V
HOFLKGFK_00141 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HOFLKGFK_00142 1.5e-82 yraN L Belongs to the UPF0102 family
HOFLKGFK_00143 1.7e-285 comM O Magnesium chelatase, subunit ChlI C-terminal
HOFLKGFK_00144 5.9e-255 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HOFLKGFK_00145 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HOFLKGFK_00146 5.2e-178 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
HOFLKGFK_00147 4.8e-117 safC S O-methyltransferase
HOFLKGFK_00148 9.5e-245 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HOFLKGFK_00150 6.1e-241 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HOFLKGFK_00151 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOFLKGFK_00152 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOFLKGFK_00153 9.2e-311 E ABC transporter, substrate-binding protein, family 5
HOFLKGFK_00154 2.9e-258 EGP Major facilitator Superfamily
HOFLKGFK_00155 2.4e-251 rarA L Recombination factor protein RarA
HOFLKGFK_00156 0.0 L DEAD DEAH box helicase
HOFLKGFK_00157 4.3e-191 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
HOFLKGFK_00158 1.7e-199 gluD E Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00159 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00160 2e-152 gluB ET Belongs to the bacterial solute-binding protein 3 family
HOFLKGFK_00161 7.5e-144 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
HOFLKGFK_00162 2.8e-137 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
HOFLKGFK_00163 7.1e-281 glnP E Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00164 9.4e-236 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HOFLKGFK_00165 8.2e-80 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HOFLKGFK_00166 1.6e-94 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HOFLKGFK_00167 6.6e-151 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HOFLKGFK_00168 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HOFLKGFK_00169 1.6e-140 3.5.2.10 S Creatinine amidohydrolase
HOFLKGFK_00170 5.5e-245 proP EGP Sugar (and other) transporter
HOFLKGFK_00171 1.4e-284 purR QT Purine catabolism regulatory protein-like family
HOFLKGFK_00172 8.3e-254 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
HOFLKGFK_00173 0.0 clpC O ATPase family associated with various cellular activities (AAA)
HOFLKGFK_00174 4.6e-188 uspA T Belongs to the universal stress protein A family
HOFLKGFK_00176 2.3e-167 S Protein of unknown function (DUF3027)
HOFLKGFK_00177 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
HOFLKGFK_00178 2.2e-54 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HOFLKGFK_00179 3.6e-261 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HOFLKGFK_00180 6.8e-133 KT Response regulator receiver domain protein
HOFLKGFK_00181 1.3e-124
HOFLKGFK_00183 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HOFLKGFK_00184 8.5e-77 S LytR cell envelope-related transcriptional attenuator
HOFLKGFK_00185 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HOFLKGFK_00186 1.8e-67 moxR S ATPase family associated with various cellular activities (AAA)
HOFLKGFK_00187 3.1e-81 moxR S ATPase family associated with various cellular activities (AAA)
HOFLKGFK_00188 5.5e-175 S Protein of unknown function DUF58
HOFLKGFK_00189 3.6e-91
HOFLKGFK_00190 8.3e-177 S von Willebrand factor (vWF) type A domain
HOFLKGFK_00191 4.1e-182 S von Willebrand factor (vWF) type A domain
HOFLKGFK_00192 4.6e-60
HOFLKGFK_00193 2.7e-277 S PGAP1-like protein
HOFLKGFK_00194 1.6e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HOFLKGFK_00195 0.0 S Lysylphosphatidylglycerol synthase TM region
HOFLKGFK_00196 1.4e-41 hup L Belongs to the bacterial histone-like protein family
HOFLKGFK_00197 1.8e-57
HOFLKGFK_00198 2.2e-25 C FMN binding
HOFLKGFK_00199 1.4e-75 C FMN binding
HOFLKGFK_00200 2.6e-280 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HOFLKGFK_00201 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HOFLKGFK_00202 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
HOFLKGFK_00203 1e-301 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HOFLKGFK_00204 5.7e-155 arc O AAA ATPase forming ring-shaped complexes
HOFLKGFK_00205 2.4e-114 arc O AAA ATPase forming ring-shaped complexes
HOFLKGFK_00206 3.5e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HOFLKGFK_00207 1.1e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOFLKGFK_00208 3.5e-79 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HOFLKGFK_00209 5.6e-45 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HOFLKGFK_00210 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOFLKGFK_00211 4.2e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOFLKGFK_00212 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HOFLKGFK_00213 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HOFLKGFK_00215 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HOFLKGFK_00216 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HOFLKGFK_00217 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HOFLKGFK_00218 2.8e-87 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HOFLKGFK_00219 4.8e-156 carA 6.3.5.5 F Belongs to the CarA family
HOFLKGFK_00220 2.2e-56 carA 6.3.5.5 F Belongs to the CarA family
HOFLKGFK_00221 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOFLKGFK_00222 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOFLKGFK_00223 3.8e-50 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOFLKGFK_00224 7e-98 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOFLKGFK_00225 4.3e-52 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOFLKGFK_00226 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOFLKGFK_00227 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HOFLKGFK_00228 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HOFLKGFK_00229 8.1e-188 yocS S SBF-like CPA transporter family (DUF4137)
HOFLKGFK_00231 8.5e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
HOFLKGFK_00232 1.5e-225 M Glycosyl transferase 4-like domain
HOFLKGFK_00233 1.1e-228 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HOFLKGFK_00234 1.5e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HOFLKGFK_00235 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HOFLKGFK_00236 5.8e-30
HOFLKGFK_00237 3.6e-307 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
HOFLKGFK_00238 3.9e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOFLKGFK_00239 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HOFLKGFK_00240 2.8e-235 purD 6.3.4.13 F Belongs to the GARS family
HOFLKGFK_00241 2.1e-247 EGP Major facilitator Superfamily
HOFLKGFK_00242 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HOFLKGFK_00243 1.1e-214 1.1.1.1 C Iron-containing alcohol dehydrogenase
HOFLKGFK_00244 3.3e-129 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HOFLKGFK_00245 2.8e-162 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
HOFLKGFK_00246 3.6e-202 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
HOFLKGFK_00247 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HOFLKGFK_00248 2.3e-89 zur P Belongs to the Fur family
HOFLKGFK_00249 2.2e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HOFLKGFK_00250 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HOFLKGFK_00251 2.6e-183 adh3 C Zinc-binding dehydrogenase
HOFLKGFK_00252 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOFLKGFK_00253 2.6e-256 macB_8 V MacB-like periplasmic core domain
HOFLKGFK_00255 1.6e-42 M Conserved repeat domain
HOFLKGFK_00256 9.3e-104 M Conserved repeat domain
HOFLKGFK_00257 2e-58 V ATPases associated with a variety of cellular activities
HOFLKGFK_00258 2.5e-66 V ATPases associated with a variety of cellular activities
HOFLKGFK_00259 4.3e-75
HOFLKGFK_00260 1.5e-14 S Domain of unknown function (DUF4143)
HOFLKGFK_00261 3.1e-127 XK27_08050 O prohibitin homologues
HOFLKGFK_00262 1.4e-43 XAC3035 O Glutaredoxin
HOFLKGFK_00263 3.2e-75 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HOFLKGFK_00264 3.1e-220 mtnE 2.6.1.83 E Aminotransferase class I and II
HOFLKGFK_00265 4.9e-98 metI P Psort location CytoplasmicMembrane, score 9.99
HOFLKGFK_00266 6.5e-165 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOFLKGFK_00267 1.5e-18 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOFLKGFK_00268 9.9e-155 metQ M NLPA lipoprotein
HOFLKGFK_00269 1.4e-200 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HOFLKGFK_00270 9e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
HOFLKGFK_00271 1.5e-152 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
HOFLKGFK_00272 3.6e-120 E Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00273 1.1e-108 papP E Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00274 1e-113 K acetyltransferase
HOFLKGFK_00278 0.0 tetP J Elongation factor G, domain IV
HOFLKGFK_00280 9.9e-130 ydcZ S Putative inner membrane exporter, YdcZ
HOFLKGFK_00282 2e-214 ybiR P Citrate transporter
HOFLKGFK_00283 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HOFLKGFK_00284 1.3e-306 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOFLKGFK_00285 7.9e-143 yhdG E aromatic amino acid transport protein AroP K03293
HOFLKGFK_00286 1.6e-114 yhdG E aromatic amino acid transport protein AroP K03293
HOFLKGFK_00287 2.7e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOFLKGFK_00288 1.9e-91 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HOFLKGFK_00289 1.5e-304 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HOFLKGFK_00290 0.0 macB_2 V ATPases associated with a variety of cellular activities
HOFLKGFK_00291 1e-218 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HOFLKGFK_00292 1.5e-191 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HOFLKGFK_00293 2.3e-139 sapF E ATPases associated with a variety of cellular activities
HOFLKGFK_00294 1.4e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
HOFLKGFK_00295 2.8e-139 EP Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00296 1.3e-28 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00297 6.3e-46 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00298 1.1e-59 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00299 1.8e-24 E ABC transporter, substrate-binding protein, family 5
HOFLKGFK_00300 1.4e-196 E ABC transporter, substrate-binding protein, family 5
HOFLKGFK_00301 7e-242 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HOFLKGFK_00302 2.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HOFLKGFK_00303 3.4e-166 G Bacterial extracellular solute-binding protein
HOFLKGFK_00304 7.2e-81 G Bacterial extracellular solute-binding protein
HOFLKGFK_00305 2.2e-246 G Bacterial extracellular solute-binding protein
HOFLKGFK_00306 0.0 abfA1 3.2.1.55 GH51 G arabinose metabolic process
HOFLKGFK_00307 2.4e-175 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HOFLKGFK_00308 8.8e-231 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HOFLKGFK_00309 3.4e-115 S CRISPR-associated protein (Cas_Csn2)
HOFLKGFK_00310 6e-18 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOFLKGFK_00311 9.7e-166 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOFLKGFK_00312 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HOFLKGFK_00313 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HOFLKGFK_00314 1e-257 lacS G Psort location CytoplasmicMembrane, score 10.00
HOFLKGFK_00315 3.4e-183 lacR K Transcriptional regulator, LacI family
HOFLKGFK_00316 0.0 V ABC transporter transmembrane region
HOFLKGFK_00317 0.0 V ABC transporter, ATP-binding protein
HOFLKGFK_00318 4.6e-97 K MarR family
HOFLKGFK_00319 9.1e-147 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HOFLKGFK_00320 5.8e-240 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HOFLKGFK_00321 9.6e-106 K Bacterial regulatory proteins, tetR family
HOFLKGFK_00322 2.2e-197 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HOFLKGFK_00323 7.9e-180 G Transporter major facilitator family protein
HOFLKGFK_00324 0.0 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
HOFLKGFK_00325 1.3e-214 EGP Major facilitator Superfamily
HOFLKGFK_00326 8.9e-118 K Periplasmic binding protein domain
HOFLKGFK_00327 3.4e-15 K helix_turn_helix, mercury resistance
HOFLKGFK_00328 8e-221 lmrB U Major Facilitator Superfamily
HOFLKGFK_00329 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
HOFLKGFK_00330 2.3e-108 K Bacterial regulatory proteins, tetR family
HOFLKGFK_00331 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HOFLKGFK_00332 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
HOFLKGFK_00333 8.9e-247 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HOFLKGFK_00334 1.5e-151 P Major Facilitator Superfamily
HOFLKGFK_00335 7e-75 mcyA Q Nodulation protein S (NodS)
HOFLKGFK_00336 1.9e-209 hsvB 6.3.2.4 M Belongs to the D-alanine--D-alanine ligase family
HOFLKGFK_00337 2e-130 ydjE EGP Major facilitator Superfamily
HOFLKGFK_00338 2.6e-20 Q Belongs to the P-Pant transferase superfamily
HOFLKGFK_00340 1.2e-271 srfJ1 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HOFLKGFK_00342 8.5e-106 G Transporter major facilitator family protein
HOFLKGFK_00343 1.1e-105 yjjL G MFS/sugar transport protein
HOFLKGFK_00344 1.7e-111 K Bacterial regulatory proteins, tetR family
HOFLKGFK_00345 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
HOFLKGFK_00346 3.7e-12 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
HOFLKGFK_00347 5.7e-120 K Bacterial regulatory proteins, tetR family
HOFLKGFK_00348 5.5e-255 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
HOFLKGFK_00349 5.5e-161 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HOFLKGFK_00350 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HOFLKGFK_00351 3.9e-156 hgdC I BadF/BadG/BcrA/BcrD ATPase family
HOFLKGFK_00352 1.6e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOFLKGFK_00353 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HOFLKGFK_00354 3.8e-58 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HOFLKGFK_00355 2.6e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOFLKGFK_00356 1.4e-21 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOFLKGFK_00358 6.2e-199 S Endonuclease/Exonuclease/phosphatase family
HOFLKGFK_00359 3.4e-22 M cell wall anchor domain protein
HOFLKGFK_00360 1.3e-99 tmp1 S Domain of unknown function (DUF4391)
HOFLKGFK_00361 1.5e-39 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HOFLKGFK_00362 1.2e-113 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HOFLKGFK_00363 1.1e-233 aspB E Aminotransferase class-V
HOFLKGFK_00364 1.9e-70 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HOFLKGFK_00365 7.2e-189 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
HOFLKGFK_00366 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
HOFLKGFK_00367 5.4e-141 V Domain of unknown function (DUF3427)
HOFLKGFK_00368 4e-53 K TfoX N-terminal domain
HOFLKGFK_00369 9.2e-25 S Polyketide cyclase / dehydrase and lipid transport
HOFLKGFK_00370 1.2e-88 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HOFLKGFK_00371 1.7e-87 3.1.21.7 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HOFLKGFK_00373 1.8e-49 V Domain of unknown function (DUF3427)
HOFLKGFK_00374 1.5e-76
HOFLKGFK_00375 9.8e-53 S Bacterial PH domain
HOFLKGFK_00376 6.7e-248 S zinc finger
HOFLKGFK_00377 5.4e-57 T helix_turn_helix, Lux Regulon
HOFLKGFK_00378 8.7e-29 2.7.13.3 T Histidine kinase
HOFLKGFK_00379 3.2e-118 ytrE V ATPases associated with a variety of cellular activities
HOFLKGFK_00380 4.7e-219 EGP Major facilitator Superfamily
HOFLKGFK_00381 1.2e-137 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HOFLKGFK_00382 1.8e-217 S Domain of unknown function (DUF5067)
HOFLKGFK_00383 1.2e-263 glnA2 6.3.1.2 E glutamine synthetase
HOFLKGFK_00384 4.1e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HOFLKGFK_00385 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOFLKGFK_00386 1.5e-122
HOFLKGFK_00387 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HOFLKGFK_00388 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOFLKGFK_00389 2.4e-259 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HOFLKGFK_00390 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HOFLKGFK_00391 5.4e-239 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HOFLKGFK_00392 1.2e-96 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HOFLKGFK_00393 1.3e-48 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HOFLKGFK_00394 4.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HOFLKGFK_00395 1.2e-30 3.1.21.3 V DivIVA protein
HOFLKGFK_00396 6.9e-41 yggT S YGGT family
HOFLKGFK_00397 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HOFLKGFK_00398 4.4e-135 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOFLKGFK_00399 1.9e-36 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOFLKGFK_00400 2.2e-245 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOFLKGFK_00401 1.3e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HOFLKGFK_00402 1e-105 S Pilus assembly protein, PilO
HOFLKGFK_00403 8.1e-166 pilN NU PFAM Fimbrial assembly family protein
HOFLKGFK_00404 2.5e-189 pilM NU Type IV pilus assembly protein PilM;
HOFLKGFK_00405 2.4e-150 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HOFLKGFK_00406 1.3e-20
HOFLKGFK_00407 0.0
HOFLKGFK_00408 4.7e-230 pilC U Type II secretion system (T2SS), protein F
HOFLKGFK_00409 2.4e-46 pilA NU Prokaryotic N-terminal methylation motif
HOFLKGFK_00410 2.1e-104 S Prokaryotic N-terminal methylation motif
HOFLKGFK_00411 2.4e-136 ppdC NU Prokaryotic N-terminal methylation motif
HOFLKGFK_00412 4.4e-34 pulE NU Type II/IV secretion system protein
HOFLKGFK_00413 4.5e-280 pulE NU Type II/IV secretion system protein
HOFLKGFK_00414 8e-161 pilT NU Type II/IV secretion system protein
HOFLKGFK_00415 4.3e-172 pilT NU Type II/IV secretion system protein
HOFLKGFK_00416 0.0
HOFLKGFK_00417 8.1e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HOFLKGFK_00418 5.4e-133 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HOFLKGFK_00419 1.2e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HOFLKGFK_00420 3e-60 S Thiamine-binding protein
HOFLKGFK_00421 3.7e-193 K helix_turn _helix lactose operon repressor
HOFLKGFK_00422 2.8e-241 lacY P LacY proton/sugar symporter
HOFLKGFK_00423 1e-92 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HOFLKGFK_00424 5.3e-189 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HOFLKGFK_00425 5.5e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00426 7e-206 P NMT1/THI5 like
HOFLKGFK_00427 3.2e-218 iunH1 3.2.2.1 F nucleoside hydrolase
HOFLKGFK_00428 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOFLKGFK_00429 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
HOFLKGFK_00430 0.0 I acetylesterase activity
HOFLKGFK_00431 5.6e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HOFLKGFK_00432 8.5e-218 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HOFLKGFK_00433 5.5e-108 2.7.11.1 NU Tfp pilus assembly protein FimV
HOFLKGFK_00434 5.1e-119 2.7.11.1 NU Tfp pilus assembly protein FimV
HOFLKGFK_00436 2.7e-73 S Protein of unknown function (DUF3052)
HOFLKGFK_00437 1e-154 lon T Belongs to the peptidase S16 family
HOFLKGFK_00438 2.3e-136 S Zincin-like metallopeptidase
HOFLKGFK_00439 1.5e-136 S Zincin-like metallopeptidase
HOFLKGFK_00440 1.6e-282 uvrD2 3.6.4.12 L DNA helicase
HOFLKGFK_00441 4.7e-269 mphA S Aminoglycoside phosphotransferase
HOFLKGFK_00442 3.6e-32 S Protein of unknown function (DUF3107)
HOFLKGFK_00443 1.1e-172 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
HOFLKGFK_00444 2.1e-117 S Vitamin K epoxide reductase
HOFLKGFK_00445 7.8e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HOFLKGFK_00446 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HOFLKGFK_00447 1.2e-21 S Patatin-like phospholipase
HOFLKGFK_00448 5.1e-187 K LysR substrate binding domain protein
HOFLKGFK_00449 7.4e-241 patB 4.4.1.8 E Aminotransferase, class I II
HOFLKGFK_00450 1e-119 S Phospholipase/Carboxylesterase
HOFLKGFK_00451 5e-27
HOFLKGFK_00454 7.3e-33
HOFLKGFK_00455 2.1e-126 L HTH-like domain
HOFLKGFK_00456 2e-42 L transposase activity
HOFLKGFK_00457 5.9e-17 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HOFLKGFK_00458 4e-226 xylR GK ROK family
HOFLKGFK_00459 3.5e-87 ykoE S ABC-type cobalt transport system, permease component
HOFLKGFK_00460 1.3e-16 ydcZ S Putative inner membrane exporter, YdcZ
HOFLKGFK_00461 3.4e-107 S Membrane
HOFLKGFK_00462 2.7e-277 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HOFLKGFK_00463 1.7e-248 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
HOFLKGFK_00464 3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HOFLKGFK_00465 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
HOFLKGFK_00466 2.2e-48 K Bacterial regulatory proteins, lacI family
HOFLKGFK_00467 5.3e-122 K Bacterial regulatory proteins, lacI family
HOFLKGFK_00468 1.4e-114 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
HOFLKGFK_00469 1.2e-97 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
HOFLKGFK_00470 1.7e-185 MA20_14025 U Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00471 1.4e-33 MA20_14020 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00472 1.5e-89 MA20_14020 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00473 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HOFLKGFK_00474 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
HOFLKGFK_00475 1e-105 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HOFLKGFK_00476 8.5e-287 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HOFLKGFK_00477 5.9e-222 xylR GK ROK family
HOFLKGFK_00479 1.5e-35 rpmE J Binds the 23S rRNA
HOFLKGFK_00480 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HOFLKGFK_00481 3.2e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HOFLKGFK_00482 1.1e-24 livK E Receptor family ligand binding region
HOFLKGFK_00483 1.8e-184 livK E Receptor family ligand binding region
HOFLKGFK_00484 6.1e-130 U Belongs to the binding-protein-dependent transport system permease family
HOFLKGFK_00485 3.3e-195 livM U Belongs to the binding-protein-dependent transport system permease family
HOFLKGFK_00486 1.5e-24 E Branched-chain amino acid ATP-binding cassette transporter
HOFLKGFK_00487 6.9e-110 E Branched-chain amino acid ATP-binding cassette transporter
HOFLKGFK_00488 4.5e-37 livF E ATPases associated with a variety of cellular activities
HOFLKGFK_00489 1.9e-26 livF E ATPases associated with a variety of cellular activities
HOFLKGFK_00490 2.6e-39 livF E ATPases associated with a variety of cellular activities
HOFLKGFK_00491 6.4e-114 ywlC 2.7.7.87 J Belongs to the SUA5 family
HOFLKGFK_00492 3.8e-194 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HOFLKGFK_00493 2.2e-287 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HOFLKGFK_00494 3.7e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HOFLKGFK_00495 7.2e-161 supH S Sucrose-6F-phosphate phosphohydrolase
HOFLKGFK_00496 7.9e-271 recD2 3.6.4.12 L PIF1-like helicase
HOFLKGFK_00497 2.8e-165 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HOFLKGFK_00498 1.7e-182 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HOFLKGFK_00499 1.4e-98 L Single-strand binding protein family
HOFLKGFK_00500 0.0 pepO 3.4.24.71 O Peptidase family M13
HOFLKGFK_00501 5.8e-48 map 3.4.11.18 E Methionine aminopeptidase
HOFLKGFK_00502 2e-79 map 3.4.11.18 E Methionine aminopeptidase
HOFLKGFK_00503 2.3e-248 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HOFLKGFK_00504 1.7e-142 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HOFLKGFK_00505 4e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOFLKGFK_00506 1.1e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HOFLKGFK_00507 3.1e-168 ftsE D Cell division ATP-binding protein FtsE
HOFLKGFK_00508 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HOFLKGFK_00509 2.9e-148 usp 3.5.1.28 CBM50 D CHAP domain protein
HOFLKGFK_00510 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HOFLKGFK_00511 4.3e-116 pknD ET ABC transporter, substrate-binding protein, family 3
HOFLKGFK_00512 1e-35 pknD ET ABC transporter, substrate-binding protein, family 3
HOFLKGFK_00513 1.2e-150 pknD ET ABC transporter, substrate-binding protein, family 3
HOFLKGFK_00514 2.2e-142 yecS E Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00515 8.5e-145 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
HOFLKGFK_00516 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HOFLKGFK_00517 2.1e-131 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HOFLKGFK_00518 5.3e-229 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HOFLKGFK_00519 1.4e-189 K Periplasmic binding protein domain
HOFLKGFK_00520 0.0 XK27_00515 D Cell surface antigen C-terminus
HOFLKGFK_00521 1.2e-86 M domain protein
HOFLKGFK_00522 4.8e-12 O Pkd domain containing protein
HOFLKGFK_00523 1.4e-62 S Listeria-Bacteroides repeat domain (List_Bact_rpt)
HOFLKGFK_00524 1.3e-71 M Sortase family
HOFLKGFK_00525 4e-38 D nuclear chromosome segregation
HOFLKGFK_00528 4.7e-257 U Type IV secretory pathway, VirB4
HOFLKGFK_00529 2.9e-287 U TraM recognition site of TraD and TraG
HOFLKGFK_00534 1e-47
HOFLKGFK_00536 2.6e-23 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HOFLKGFK_00537 2.9e-52 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HOFLKGFK_00538 4.6e-271 V N-6 DNA Methylase
HOFLKGFK_00539 4.4e-82 pin L Resolvase, N terminal domain
HOFLKGFK_00540 8.9e-76
HOFLKGFK_00542 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HOFLKGFK_00543 1.9e-09 L Psort location Cytoplasmic, score 8.96
HOFLKGFK_00547 9.4e-21
HOFLKGFK_00549 4e-93 topB 5.99.1.2 L DNA topoisomerase
HOFLKGFK_00550 1.7e-83 topB 5.99.1.2 L DNA topoisomerase
HOFLKGFK_00552 8.5e-77 XK27_08505 D nucleotidyltransferase activity
HOFLKGFK_00553 9.2e-37 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
HOFLKGFK_00554 1e-30 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HOFLKGFK_00555 2.3e-32
HOFLKGFK_00556 0.0 traA 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HOFLKGFK_00558 5.3e-95
HOFLKGFK_00559 5.9e-22 S Fic/DOC family
HOFLKGFK_00560 1.3e-53 L single-stranded DNA binding
HOFLKGFK_00562 1.9e-99 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HOFLKGFK_00563 3.7e-94 S Protein of unknown function (DUF2786)
HOFLKGFK_00566 3.3e-09
HOFLKGFK_00567 5.7e-85 K Cro/C1-type HTH DNA-binding domain
HOFLKGFK_00568 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HOFLKGFK_00569 2.1e-296 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HOFLKGFK_00570 2.4e-308 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HOFLKGFK_00571 1.1e-121 S Short repeat of unknown function (DUF308)
HOFLKGFK_00572 2.7e-49 S Antitoxin component of a toxin-antitoxin (TA) module
HOFLKGFK_00573 3.4e-55 DJ Addiction module toxin, RelE StbE family
HOFLKGFK_00575 4.8e-188 EGP Major facilitator Superfamily
HOFLKGFK_00576 1.6e-40 EGP Major facilitator Superfamily
HOFLKGFK_00577 1.9e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOFLKGFK_00578 1.6e-22 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOFLKGFK_00579 2e-269 KLT Domain of unknown function (DUF4032)
HOFLKGFK_00580 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
HOFLKGFK_00581 2.8e-131 K LytTr DNA-binding domain
HOFLKGFK_00582 3.6e-74 T GHKL domain
HOFLKGFK_00583 4.8e-138 T GHKL domain
HOFLKGFK_00584 6.4e-58
HOFLKGFK_00585 1.8e-216 clcA_2 P Voltage gated chloride channel
HOFLKGFK_00586 2.6e-47 S Psort location Cytoplasmic, score
HOFLKGFK_00587 1e-78
HOFLKGFK_00588 2.6e-138
HOFLKGFK_00589 4e-99 3.4.22.70 M Sortase family
HOFLKGFK_00590 4.8e-115 M LPXTG-motif cell wall anchor domain protein
HOFLKGFK_00591 0.0 S LPXTG-motif cell wall anchor domain protein
HOFLKGFK_00592 1.3e-224 S LPXTG-motif cell wall anchor domain protein
HOFLKGFK_00593 3.7e-10 S LPXTG-motif cell wall anchor domain protein
HOFLKGFK_00594 1.3e-72 S GtrA-like protein
HOFLKGFK_00595 2.2e-90 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HOFLKGFK_00596 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HOFLKGFK_00597 9.8e-121 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
HOFLKGFK_00598 9.9e-79 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
HOFLKGFK_00599 1.7e-38 vex2 V ABC transporter, ATP-binding protein
HOFLKGFK_00600 1.6e-58 vex2 V ABC transporter, ATP-binding protein
HOFLKGFK_00601 6.1e-211 vex1 V Efflux ABC transporter, permease protein
HOFLKGFK_00602 1.3e-238 vex3 V ABC transporter permease
HOFLKGFK_00603 1.4e-17 lacS G Psort location CytoplasmicMembrane, score 10.00
HOFLKGFK_00604 1.7e-42 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HOFLKGFK_00605 4.4e-229 yhjX EGP Major facilitator Superfamily
HOFLKGFK_00606 1.4e-257 trxB1 1.8.1.9 C Thioredoxin domain
HOFLKGFK_00607 2.4e-34 trxB1 1.8.1.9 C Thioredoxin domain
HOFLKGFK_00608 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HOFLKGFK_00609 2e-10 K sequence-specific DNA binding
HOFLKGFK_00614 4.4e-14
HOFLKGFK_00617 6.8e-26 S Domain of unknown function (DUF3846)
HOFLKGFK_00620 2.1e-25
HOFLKGFK_00626 6.1e-12 L Psort location Cytoplasmic, score
HOFLKGFK_00628 2.1e-13 recQ 3.6.4.12, 5.99.1.2 F RecQ zinc-binding
HOFLKGFK_00629 4.6e-120 recQ 3.6.4.12, 5.99.1.2 F RecQ zinc-binding
HOFLKGFK_00630 1.7e-55 3.1.21.3 V Type I restriction modification DNA specificity domain
HOFLKGFK_00633 1.2e-63 V Restriction endonuclease
HOFLKGFK_00634 3.6e-24
HOFLKGFK_00635 5.4e-93 pin L Resolvase, N terminal domain
HOFLKGFK_00637 2e-78 L helicase
HOFLKGFK_00639 1.7e-10
HOFLKGFK_00642 7.9e-11
HOFLKGFK_00650 6.3e-38
HOFLKGFK_00651 5.2e-122 L Phage integrase family
HOFLKGFK_00652 2.2e-88 I alpha/beta hydrolase fold
HOFLKGFK_00654 2.8e-145 cobB2 K Sir2 family
HOFLKGFK_00655 4.1e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HOFLKGFK_00656 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HOFLKGFK_00657 2.6e-158 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00658 1.2e-158 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00659 4.4e-244 msmE7 G Bacterial extracellular solute-binding protein
HOFLKGFK_00660 2.2e-229 nagC GK ROK family
HOFLKGFK_00661 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HOFLKGFK_00662 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HOFLKGFK_00663 0.0 yjcE P Sodium/hydrogen exchanger family
HOFLKGFK_00664 1.2e-154 ypfH S Phospholipase/Carboxylesterase
HOFLKGFK_00665 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HOFLKGFK_00666 2.1e-62
HOFLKGFK_00668 4.2e-75 S Pfam:CtkA_N
HOFLKGFK_00670 3.6e-104
HOFLKGFK_00671 1.3e-24
HOFLKGFK_00675 3.1e-44
HOFLKGFK_00676 1.2e-205
HOFLKGFK_00678 3.1e-15 S COG NOG14600 non supervised orthologous group
HOFLKGFK_00680 1.3e-72
HOFLKGFK_00683 1.3e-159 mltE2 M Bacteriophage peptidoglycan hydrolase
HOFLKGFK_00684 3.8e-08 L Phage integrase family
HOFLKGFK_00685 4.4e-121 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HOFLKGFK_00686 2.3e-167 F Inosine-uridine preferring nucleoside hydrolase
HOFLKGFK_00687 3.6e-200 bdhA C Iron-containing alcohol dehydrogenase
HOFLKGFK_00688 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
HOFLKGFK_00690 1.9e-117 L Integrase core domain
HOFLKGFK_00691 0.0 3.2.1.8 G Glycosyl hydrolase family 10
HOFLKGFK_00692 4.6e-229 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HOFLKGFK_00693 0.0 O Highly conserved protein containing a thioredoxin domain
HOFLKGFK_00694 2e-186 L PFAM Integrase catalytic
HOFLKGFK_00695 1.5e-81 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
HOFLKGFK_00696 2.5e-74 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HOFLKGFK_00697 1.5e-180 V Beta-lactamase
HOFLKGFK_00698 0.0 yjjK S ATP-binding cassette protein, ChvD family
HOFLKGFK_00699 8.5e-165 tesB I Thioesterase-like superfamily
HOFLKGFK_00700 3.1e-93 S Protein of unknown function (DUF3180)
HOFLKGFK_00701 8.3e-274 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HOFLKGFK_00702 1.5e-155 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HOFLKGFK_00703 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HOFLKGFK_00704 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOFLKGFK_00705 1.1e-17 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HOFLKGFK_00706 6.1e-68 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HOFLKGFK_00707 1.5e-200 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HOFLKGFK_00708 1.1e-232 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
HOFLKGFK_00709 6.3e-232 epsG M Glycosyl transferase family 21
HOFLKGFK_00710 1.3e-237 S AI-2E family transporter
HOFLKGFK_00711 5.5e-180 3.4.14.13 M Glycosyltransferase like family 2
HOFLKGFK_00712 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
HOFLKGFK_00713 0.0 yliE T Putative diguanylate phosphodiesterase
HOFLKGFK_00714 2.2e-111 S Domain of unknown function (DUF4956)
HOFLKGFK_00715 1.4e-158 P VTC domain
HOFLKGFK_00716 0.0 cotH M CotH kinase protein
HOFLKGFK_00717 4.3e-278 pelG S Putative exopolysaccharide Exporter (EPS-E)
HOFLKGFK_00718 1.1e-129 pelF GT4 M Domain of unknown function (DUF3492)
HOFLKGFK_00719 1.9e-104 pelF GT4 M Domain of unknown function (DUF3492)
HOFLKGFK_00720 7.4e-17 S Uncharacterised protein conserved in bacteria (DUF2194)
HOFLKGFK_00721 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
HOFLKGFK_00722 4.5e-100
HOFLKGFK_00723 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
HOFLKGFK_00727 2.7e-163 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HOFLKGFK_00728 7.6e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HOFLKGFK_00730 3.6e-85 ptpA 3.1.3.48 T low molecular weight
HOFLKGFK_00731 2.1e-128 folA 1.5.1.3 H dihydrofolate reductase
HOFLKGFK_00732 3.8e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOFLKGFK_00733 7.7e-73 attW O OsmC-like protein
HOFLKGFK_00734 1.3e-190 T Universal stress protein family
HOFLKGFK_00735 1.3e-79 M NlpC/P60 family
HOFLKGFK_00736 1.6e-166 usp 3.5.1.28 CBM50 S CHAP domain
HOFLKGFK_00737 1.1e-180 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HOFLKGFK_00738 6.2e-41
HOFLKGFK_00739 2.3e-215 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HOFLKGFK_00740 2.5e-105 phoU P Plays a role in the regulation of phosphate uptake
HOFLKGFK_00741 0.0 4.2.1.53 S MCRA family
HOFLKGFK_00742 2.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOFLKGFK_00743 4e-204 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HOFLKGFK_00744 3.2e-99 S Serine aminopeptidase, S33
HOFLKGFK_00745 7.4e-250 G Psort location CytoplasmicMembrane, score 10.00
HOFLKGFK_00746 2.5e-192 K helix_turn _helix lactose operon repressor
HOFLKGFK_00747 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HOFLKGFK_00749 1.8e-212 araJ EGP Major facilitator Superfamily
HOFLKGFK_00750 7.2e-290 S Domain of unknown function (DUF4037)
HOFLKGFK_00751 9.6e-74 S Domain of unknown function (DUF4037)
HOFLKGFK_00752 4.6e-88 S Protein of unknown function (DUF4125)
HOFLKGFK_00753 7.1e-93
HOFLKGFK_00754 2.4e-145 pspC KT PspC domain
HOFLKGFK_00755 8.1e-264 tcsS3 KT PspC domain
HOFLKGFK_00756 1.9e-121 degU K helix_turn_helix, Lux Regulon
HOFLKGFK_00757 2.4e-101 Q Isochorismatase family
HOFLKGFK_00758 1.1e-270 U Permease for cytosine/purines, uracil, thiamine, allantoin
HOFLKGFK_00759 8.3e-190 yegV G pfkB family carbohydrate kinase
HOFLKGFK_00760 6.7e-187 yegU O ADP-ribosylglycohydrolase
HOFLKGFK_00762 1.3e-262 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOFLKGFK_00763 2.2e-128 I Diacylglycerol kinase catalytic domain
HOFLKGFK_00764 2.8e-157 arbG K CAT RNA binding domain
HOFLKGFK_00765 0.0 crr G pts system, glucose-specific IIABC component
HOFLKGFK_00766 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HOFLKGFK_00767 3.6e-07 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HOFLKGFK_00768 1e-150 T LytTr DNA-binding domain
HOFLKGFK_00769 5.7e-250 T GHKL domain
HOFLKGFK_00770 7.5e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOFLKGFK_00771 1.7e-71 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOFLKGFK_00772 2.2e-88 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HOFLKGFK_00774 5.5e-107
HOFLKGFK_00775 4.1e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOFLKGFK_00776 1.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HOFLKGFK_00777 2.5e-187 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HOFLKGFK_00778 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HOFLKGFK_00779 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HOFLKGFK_00780 4.8e-28
HOFLKGFK_00781 1.3e-190 nusA K Participates in both transcription termination and antitermination
HOFLKGFK_00782 2e-102
HOFLKGFK_00784 4.4e-183 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HOFLKGFK_00785 1e-65 rplQ J Ribosomal protein L17
HOFLKGFK_00786 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFLKGFK_00787 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOFLKGFK_00788 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOFLKGFK_00789 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HOFLKGFK_00790 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOFLKGFK_00791 5.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HOFLKGFK_00792 3.8e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HOFLKGFK_00793 9.8e-74 rplO J binds to the 23S rRNA
HOFLKGFK_00794 3.4e-25 rpmD J Ribosomal protein L30p/L7e
HOFLKGFK_00795 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HOFLKGFK_00796 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HOFLKGFK_00797 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOFLKGFK_00798 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HOFLKGFK_00799 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOFLKGFK_00800 1.4e-43 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOFLKGFK_00801 5.1e-25 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOFLKGFK_00802 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HOFLKGFK_00803 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HOFLKGFK_00804 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOFLKGFK_00805 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
HOFLKGFK_00806 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HOFLKGFK_00807 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOFLKGFK_00808 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOFLKGFK_00809 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOFLKGFK_00810 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOFLKGFK_00811 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HOFLKGFK_00812 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
HOFLKGFK_00813 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOFLKGFK_00814 6.4e-42 rpsJ J Involved in the binding of tRNA to the ribosomes
HOFLKGFK_00815 5.6e-55 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HOFLKGFK_00816 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HOFLKGFK_00817 8.6e-102 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HOFLKGFK_00818 5.2e-181 rhaR_1 K helix_turn_helix, arabinose operon control protein
HOFLKGFK_00819 9.5e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
HOFLKGFK_00820 1.4e-237 EGP Major facilitator Superfamily
HOFLKGFK_00821 2e-216 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HOFLKGFK_00822 3.2e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOFLKGFK_00823 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HOFLKGFK_00824 1.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HOFLKGFK_00825 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HOFLKGFK_00826 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HOFLKGFK_00827 6.9e-122
HOFLKGFK_00828 2.1e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HOFLKGFK_00829 9.4e-186 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOFLKGFK_00830 1.4e-92 M Bacterial capsule synthesis protein PGA_cap
HOFLKGFK_00831 2.4e-145 M Bacterial capsule synthesis protein PGA_cap
HOFLKGFK_00832 2.6e-14 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOFLKGFK_00833 9.4e-198 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOFLKGFK_00835 4e-197 CE10 I Belongs to the type-B carboxylesterase lipase family
HOFLKGFK_00836 2.8e-56 CE10 I Belongs to the type-B carboxylesterase lipase family
HOFLKGFK_00837 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
HOFLKGFK_00838 1.7e-231 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HOFLKGFK_00839 0.0 G Psort location Cytoplasmic, score 8.87
HOFLKGFK_00840 2.3e-121 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HOFLKGFK_00841 2.1e-172 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HOFLKGFK_00842 2.8e-151 dppF E ABC transporter
HOFLKGFK_00843 1.8e-156 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
HOFLKGFK_00844 3e-141 EP Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00845 1.3e-179 EP Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00846 1.7e-276 E Bacterial extracellular solute-binding proteins, family 5 Middle
HOFLKGFK_00847 9.7e-37 E Bacterial extracellular solute-binding proteins, family 5 Middle
HOFLKGFK_00849 9.5e-206 dapC E Aminotransferase class I and II
HOFLKGFK_00850 8.3e-59 fdxA C 4Fe-4S binding domain
HOFLKGFK_00851 4.8e-266 E aromatic amino acid transport protein AroP K03293
HOFLKGFK_00852 5.4e-204 murB 1.3.1.98 M Cell wall formation
HOFLKGFK_00853 5.5e-25 rpmG J Ribosomal protein L33
HOFLKGFK_00857 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HOFLKGFK_00858 4.7e-147
HOFLKGFK_00859 2.9e-122 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
HOFLKGFK_00860 1.4e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HOFLKGFK_00861 6.1e-30 fmdB S Putative regulatory protein
HOFLKGFK_00862 9.4e-92 flgA NO SAF
HOFLKGFK_00863 4.8e-36
HOFLKGFK_00864 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HOFLKGFK_00865 1.1e-176 T Forkhead associated domain
HOFLKGFK_00866 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HOFLKGFK_00867 6.8e-44 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOFLKGFK_00868 5.6e-28 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOFLKGFK_00869 4.2e-240 pbuO S Permease family
HOFLKGFK_00870 5.2e-143 P Zinc-uptake complex component A periplasmic
HOFLKGFK_00871 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOFLKGFK_00872 4e-168 pstA P Phosphate transport system permease
HOFLKGFK_00873 1.3e-163 pstC P probably responsible for the translocation of the substrate across the membrane
HOFLKGFK_00874 4.7e-140 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HOFLKGFK_00875 2e-24 P Part of the ABC transporter complex PstSACB involved in phosphate import
HOFLKGFK_00876 3.4e-129 KT Transcriptional regulatory protein, C terminal
HOFLKGFK_00877 2.4e-219 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HOFLKGFK_00878 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOFLKGFK_00879 1.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HOFLKGFK_00880 5.7e-211 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HOFLKGFK_00881 2.7e-139 pepC 3.4.22.40 E Peptidase C1-like family
HOFLKGFK_00882 2.2e-108 pepC 3.4.22.40 E Peptidase C1-like family
HOFLKGFK_00883 1.3e-58 D nuclear chromosome segregation
HOFLKGFK_00884 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HOFLKGFK_00885 2.5e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HOFLKGFK_00886 9e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HOFLKGFK_00887 6.3e-142 yegQ O Peptidase family U32 C-terminal domain
HOFLKGFK_00888 9.7e-141 yegQ O Peptidase family U32 C-terminal domain
HOFLKGFK_00889 9.7e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HOFLKGFK_00890 0.0 S Predicted membrane protein (DUF2207)
HOFLKGFK_00891 1.7e-91 lemA S LemA family
HOFLKGFK_00892 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HOFLKGFK_00893 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HOFLKGFK_00894 1.6e-115
HOFLKGFK_00896 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
HOFLKGFK_00897 1.2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HOFLKGFK_00898 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HOFLKGFK_00899 4.7e-302 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HOFLKGFK_00900 0.0 pccB I Carboxyl transferase domain
HOFLKGFK_00901 9.6e-289 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HOFLKGFK_00902 5.8e-40 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HOFLKGFK_00903 2.1e-79 bioY S BioY family
HOFLKGFK_00904 1e-157 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HOFLKGFK_00905 0.0
HOFLKGFK_00906 5.9e-143 QT PucR C-terminal helix-turn-helix domain
HOFLKGFK_00907 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HOFLKGFK_00908 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HOFLKGFK_00909 2.9e-129 nusG K Participates in transcription elongation, termination and antitermination
HOFLKGFK_00910 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HOFLKGFK_00912 7.4e-233 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HOFLKGFK_00913 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOFLKGFK_00914 6.5e-218 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOFLKGFK_00915 1.3e-83 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOFLKGFK_00916 2.6e-39 rpmA J Ribosomal L27 protein
HOFLKGFK_00917 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HOFLKGFK_00918 2.5e-308 rne 3.1.26.12 J Ribonuclease E/G family
HOFLKGFK_00919 1.2e-230 dapE 3.5.1.18 E Peptidase dimerisation domain
HOFLKGFK_00920 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
HOFLKGFK_00921 1.7e-108 V Efflux ABC transporter, permease protein
HOFLKGFK_00922 3.6e-152 V Efflux ABC transporter, permease protein
HOFLKGFK_00923 5e-128 V ATPases associated with a variety of cellular activities
HOFLKGFK_00924 1.5e-115 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOFLKGFK_00925 2.6e-123 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HOFLKGFK_00926 3e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HOFLKGFK_00927 0.0 pgi 5.3.1.9 G Belongs to the GPI family
HOFLKGFK_00928 5.4e-181 S Auxin Efflux Carrier
HOFLKGFK_00931 1.7e-211 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HOFLKGFK_00932 1.7e-243 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HOFLKGFK_00933 6.5e-251 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOFLKGFK_00934 2e-118 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HOFLKGFK_00935 1.2e-120 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOFLKGFK_00936 3.2e-77 soxR K MerR, DNA binding
HOFLKGFK_00937 1.7e-195 yghZ C Aldo/keto reductase family
HOFLKGFK_00938 3.2e-58 S Protein of unknown function (DUF3039)
HOFLKGFK_00939 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOFLKGFK_00940 1.4e-131
HOFLKGFK_00941 3.9e-113 yceD S Uncharacterized ACR, COG1399
HOFLKGFK_00942 1.7e-22 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HOFLKGFK_00943 4.6e-14 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HOFLKGFK_00944 1.9e-99 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HOFLKGFK_00945 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HOFLKGFK_00946 2.2e-91 ilvN 2.2.1.6 E ACT domain
HOFLKGFK_00947 6.4e-96
HOFLKGFK_00948 2.1e-13 yjjK S ABC transporter
HOFLKGFK_00949 0.0 yjjK S ABC transporter
HOFLKGFK_00950 2.2e-149 guaA1 6.3.5.2 F Peptidase C26
HOFLKGFK_00951 2.1e-302 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOFLKGFK_00952 1.6e-94
HOFLKGFK_00954 2.7e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOFLKGFK_00955 4e-179 S Endonuclease/Exonuclease/phosphatase family
HOFLKGFK_00956 1.4e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HOFLKGFK_00957 5.2e-13 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HOFLKGFK_00958 1.8e-34 CP_0960 S Belongs to the UPF0109 family
HOFLKGFK_00959 8.1e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOFLKGFK_00960 2e-149 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HOFLKGFK_00961 2.6e-101 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HOFLKGFK_00962 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
HOFLKGFK_00963 8.4e-30 rpmB J Ribosomal L28 family
HOFLKGFK_00964 0.0 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_00965 4.9e-230 yxiO S Vacuole effluxer Atg22 like
HOFLKGFK_00966 2.9e-124 gntR K FCD
HOFLKGFK_00967 3.6e-78 gntK 2.7.1.12 F Shikimate kinase
HOFLKGFK_00968 1.3e-227 gnuT EG GntP family permease
HOFLKGFK_00970 5.2e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
HOFLKGFK_00971 6.6e-22 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HOFLKGFK_00972 4.3e-194 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HOFLKGFK_00973 6.3e-125 K Bacterial regulatory proteins, tetR family
HOFLKGFK_00974 2.4e-228 MA20_36090 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_00975 1.2e-115 MA20_36090 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_00976 1e-56 MA20_36090 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_00977 1.7e-137 M Mechanosensitive ion channel
HOFLKGFK_00978 1.9e-179 S CAAX protease self-immunity
HOFLKGFK_00979 9.8e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HOFLKGFK_00980 1.7e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HOFLKGFK_00981 6.7e-175 plsC2 2.3.1.51 I Phosphate acyltransferases
HOFLKGFK_00982 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOFLKGFK_00983 5.9e-91 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
HOFLKGFK_00984 2.8e-80 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
HOFLKGFK_00985 3.5e-51 S Patatin-like phospholipase
HOFLKGFK_00986 1.4e-175 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
HOFLKGFK_00987 7.8e-302 E ABC transporter, substrate-binding protein, family 5
HOFLKGFK_00988 4.3e-55 KLT Protein tyrosine kinase
HOFLKGFK_00989 6.2e-258 EGP Transmembrane secretion effector
HOFLKGFK_00990 1.2e-167 G ABC transporter permease
HOFLKGFK_00991 1.7e-134 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_00993 6.1e-10 L Single-strand binding protein family
HOFLKGFK_00994 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOFLKGFK_00995 3e-69 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOFLKGFK_00996 1.1e-189 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOFLKGFK_00997 8.2e-140 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HOFLKGFK_00998 3.6e-269 S Calcineurin-like phosphoesterase
HOFLKGFK_01001 2.8e-38 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOFLKGFK_01002 1.4e-181 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOFLKGFK_01003 2.1e-39 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOFLKGFK_01004 1.2e-111 S Protein of unknown function (DUF805)
HOFLKGFK_01005 7e-184
HOFLKGFK_01006 1.5e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HOFLKGFK_01007 1.1e-134 EGP Major facilitator Superfamily
HOFLKGFK_01008 3.3e-115 EGP Major facilitator Superfamily
HOFLKGFK_01009 3.8e-81 S GtrA-like protein
HOFLKGFK_01010 6.7e-62 S Macrophage migration inhibitory factor (MIF)
HOFLKGFK_01011 2e-288 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HOFLKGFK_01012 0.0 pepD E Peptidase family C69
HOFLKGFK_01013 1.1e-106 S Phosphatidylethanolamine-binding protein
HOFLKGFK_01014 1.8e-207 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOFLKGFK_01015 1.7e-48 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOFLKGFK_01016 6e-39 ptsH G PTS HPr component phosphorylation site
HOFLKGFK_01017 1.3e-182 K helix_turn _helix lactose operon repressor
HOFLKGFK_01018 3e-191 holB 2.7.7.7 L DNA polymerase III
HOFLKGFK_01019 2.7e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HOFLKGFK_01020 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOFLKGFK_01021 1.4e-190 3.6.1.27 I PAP2 superfamily
HOFLKGFK_01022 5.9e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
HOFLKGFK_01023 2.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
HOFLKGFK_01024 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HOFLKGFK_01025 0.0 S Beta-L-arabinofuranosidase, GH127
HOFLKGFK_01026 7.3e-36 U Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01027 9.2e-90 U Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01028 1.2e-115 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01029 1.3e-10 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01030 1e-243 G Bacterial extracellular solute-binding protein
HOFLKGFK_01031 2.3e-203 abf G Glycosyl hydrolases family 43
HOFLKGFK_01032 1.9e-195 K helix_turn _helix lactose operon repressor
HOFLKGFK_01033 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
HOFLKGFK_01034 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
HOFLKGFK_01035 1.9e-36 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
HOFLKGFK_01036 7.6e-268 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
HOFLKGFK_01037 2.6e-146 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOFLKGFK_01038 6e-202 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOFLKGFK_01039 1.5e-302 S Calcineurin-like phosphoesterase
HOFLKGFK_01040 2.4e-115
HOFLKGFK_01041 3.8e-40
HOFLKGFK_01042 1.5e-44 K helix_turn_helix, Lux Regulon
HOFLKGFK_01043 5.1e-07 2.7.13.3 T Histidine kinase
HOFLKGFK_01044 1.3e-23 S Protein of unknown function (DUF1778)
HOFLKGFK_01045 5.9e-46 K Acetyltransferase (GNAT) family
HOFLKGFK_01047 4.2e-160 K Periplasmic binding protein domain
HOFLKGFK_01048 7.4e-142 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01049 5.7e-156 malC G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01050 4.1e-232 G Bacterial extracellular solute-binding protein
HOFLKGFK_01051 6.4e-244 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
HOFLKGFK_01052 2.7e-16 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
HOFLKGFK_01053 7.2e-69 3.2.1.22 G lipolytic protein G-D-S-L family
HOFLKGFK_01054 1.1e-274 3.2.1.22 G lipolytic protein G-D-S-L family
HOFLKGFK_01055 4.5e-80 S Domain of unknown function (DUF4143)
HOFLKGFK_01056 1.8e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOFLKGFK_01057 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
HOFLKGFK_01058 9.4e-124 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HOFLKGFK_01059 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOFLKGFK_01060 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HOFLKGFK_01061 1.1e-96 K Bacterial regulatory proteins, tetR family
HOFLKGFK_01062 1.6e-193 S Psort location CytoplasmicMembrane, score
HOFLKGFK_01063 7.8e-216 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
HOFLKGFK_01064 7.3e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
HOFLKGFK_01065 1.1e-59 U TadE-like protein
HOFLKGFK_01066 1.3e-42 S Protein of unknown function (DUF4244)
HOFLKGFK_01067 1.7e-88 gspF NU Type II secretion system (T2SS), protein F
HOFLKGFK_01068 3.4e-124 U Type ii secretion system
HOFLKGFK_01069 6.1e-185 cpaF U Type II IV secretion system protein
HOFLKGFK_01070 1.6e-140 cpaE D bacterial-type flagellum organization
HOFLKGFK_01071 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HOFLKGFK_01072 4.5e-224 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HOFLKGFK_01073 3.9e-91
HOFLKGFK_01074 2.7e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HOFLKGFK_01075 3.2e-208 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HOFLKGFK_01076 4e-11 G Bacterial Ig-like domain (group 4)
HOFLKGFK_01077 0.0 G Bacterial Ig-like domain (group 4)
HOFLKGFK_01078 2.6e-19 G Bacterial Ig-like domain (group 4)
HOFLKGFK_01079 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
HOFLKGFK_01080 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
HOFLKGFK_01081 1.4e-155 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HOFLKGFK_01082 1e-223 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HOFLKGFK_01083 1.6e-138 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01084 1.6e-166 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01085 1.4e-07 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01086 1.1e-242 G Bacterial extracellular solute-binding protein
HOFLKGFK_01087 1e-134 K Periplasmic binding protein domain
HOFLKGFK_01088 5.9e-31 K Periplasmic binding protein domain
HOFLKGFK_01089 0.0 ubiB S ABC1 family
HOFLKGFK_01090 1e-27 S granule-associated protein
HOFLKGFK_01091 1.8e-136 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HOFLKGFK_01092 2.3e-252 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HOFLKGFK_01093 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HOFLKGFK_01094 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HOFLKGFK_01095 1e-54 glnB K Nitrogen regulatory protein P-II
HOFLKGFK_01096 1.2e-236 amt U Ammonium Transporter Family
HOFLKGFK_01097 2.2e-85 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HOFLKGFK_01098 2.3e-109 icaR K Bacterial regulatory proteins, tetR family
HOFLKGFK_01100 4e-195 XK27_01805 M Glycosyltransferase like family 2
HOFLKGFK_01101 7.5e-297 pepD E Peptidase family C69
HOFLKGFK_01104 6e-38 nrdH O Glutaredoxin
HOFLKGFK_01105 1.6e-225 S Putative ABC-transporter type IV
HOFLKGFK_01106 0.0 pip S YhgE Pip domain protein
HOFLKGFK_01107 2.4e-274 pip S YhgE Pip domain protein
HOFLKGFK_01108 8.6e-87 K Psort location Cytoplasmic, score 8.87
HOFLKGFK_01109 1.1e-61 S FMN_bind
HOFLKGFK_01110 5e-148 macB V ABC transporter, ATP-binding protein
HOFLKGFK_01111 1.6e-201 Z012_06715 V FtsX-like permease family
HOFLKGFK_01113 3e-138 macB_2 V ABC transporter permease
HOFLKGFK_01114 1.9e-62 macB_2 V ABC transporter permease
HOFLKGFK_01115 2.1e-230 S Predicted membrane protein (DUF2318)
HOFLKGFK_01116 1.4e-92 tpd P Fe2+ transport protein
HOFLKGFK_01117 5.6e-298 efeU_1 P Iron permease FTR1 family
HOFLKGFK_01118 2e-237 G MFS/sugar transport protein
HOFLKGFK_01119 1.1e-117 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HOFLKGFK_01120 0.0 lmrA2 V ABC transporter transmembrane region
HOFLKGFK_01121 2.1e-285 lmrA1 V ABC transporter, ATP-binding protein
HOFLKGFK_01122 1.9e-57 ydgJ K helix_turn_helix multiple antibiotic resistance protein
HOFLKGFK_01123 1.1e-181 1.1.1.65 C Aldo/keto reductase family
HOFLKGFK_01124 2.5e-26 thiS 2.8.1.10 H ThiS family
HOFLKGFK_01125 3.8e-128 thiF 2.7.7.73, 2.7.7.80 H ThiF family
HOFLKGFK_01126 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HOFLKGFK_01127 9.9e-275 cycA E Amino acid permease
HOFLKGFK_01128 3.2e-89 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_01129 1.8e-180 M LPXTG cell wall anchor motif
HOFLKGFK_01130 6.1e-121 Q von Willebrand factor (vWF) type A domain
HOFLKGFK_01131 2.1e-175 3.4.22.70 M Sortase family
HOFLKGFK_01132 1.3e-76 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_01133 3.3e-227 P Sodium/hydrogen exchanger family
HOFLKGFK_01134 0.0 V FtsX-like permease family
HOFLKGFK_01135 5.7e-115 aroP E aromatic amino acid transport protein AroP K03293
HOFLKGFK_01136 1.1e-144 aroP E aromatic amino acid transport protein AroP K03293
HOFLKGFK_01137 7.3e-189 K helix_turn _helix lactose operon repressor
HOFLKGFK_01138 4.3e-33 G beta-mannosidase
HOFLKGFK_01139 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
HOFLKGFK_01140 6.3e-119 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOFLKGFK_01141 2.2e-55 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOFLKGFK_01142 1.8e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOFLKGFK_01143 3.5e-252 yhjE EGP Sugar (and other) transporter
HOFLKGFK_01144 2.6e-114 scrT G Transporter major facilitator family protein
HOFLKGFK_01145 5e-154 scrT G Transporter major facilitator family protein
HOFLKGFK_01146 1.6e-149 amyC5 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01147 6.4e-162 amyD3 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01148 3.8e-219 G Bacterial extracellular solute-binding protein
HOFLKGFK_01149 0.0 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
HOFLKGFK_01150 1.5e-115 S Protein of unknown function, DUF624
HOFLKGFK_01151 1.2e-296 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HOFLKGFK_01152 1.4e-195 K helix_turn _helix lactose operon repressor
HOFLKGFK_01153 5.4e-29 E Receptor family ligand binding region
HOFLKGFK_01154 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOFLKGFK_01155 7.3e-151 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOFLKGFK_01156 3.9e-131 clcA P Voltage gated chloride channel
HOFLKGFK_01157 9.3e-108 L Transposase and inactivated derivatives
HOFLKGFK_01158 3.8e-29 L transposase activity
HOFLKGFK_01159 1e-140 clcA P Voltage gated chloride channel
HOFLKGFK_01160 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOFLKGFK_01161 2.7e-137 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HOFLKGFK_01162 5.9e-47 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HOFLKGFK_01163 0.0 pip S YhgE Pip domain protein
HOFLKGFK_01164 0.0 pip S YhgE Pip domain protein
HOFLKGFK_01165 1.8e-170 yddG EG EamA-like transporter family
HOFLKGFK_01166 4.9e-56 K Helix-turn-helix XRE-family like proteins
HOFLKGFK_01168 3.6e-165 htpX O Belongs to the peptidase M48B family
HOFLKGFK_01169 4e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HOFLKGFK_01170 2.3e-187 ansA 3.5.1.1 EJ Asparaginase
HOFLKGFK_01171 0.0 cadA P E1-E2 ATPase
HOFLKGFK_01172 3.6e-285 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HOFLKGFK_01173 9.4e-269 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HOFLKGFK_01174 6.9e-09 K helix_turn_helix, Lux Regulon
HOFLKGFK_01175 2.4e-22 2.7.13.3 T Histidine kinase
HOFLKGFK_01180 2.6e-159 yicL EG EamA-like transporter family
HOFLKGFK_01181 1.2e-77 pldB 3.1.1.5 I Serine aminopeptidase, S33
HOFLKGFK_01182 5.3e-102 pldB 3.1.1.5 I Serine aminopeptidase, S33
HOFLKGFK_01183 3.2e-113 K helix_turn_helix, Lux Regulon
HOFLKGFK_01184 1.8e-120 2.7.13.3 T Histidine kinase
HOFLKGFK_01185 1e-93 2.7.13.3 T Histidine kinase
HOFLKGFK_01186 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HOFLKGFK_01187 3.6e-121 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HOFLKGFK_01188 1.2e-131 fhaA T Protein of unknown function (DUF2662)
HOFLKGFK_01189 2.8e-72 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HOFLKGFK_01190 8.2e-15 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HOFLKGFK_01191 1.6e-199 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HOFLKGFK_01192 3.8e-271 rodA D Belongs to the SEDS family
HOFLKGFK_01193 8e-266 pbpA M penicillin-binding protein
HOFLKGFK_01194 5.8e-177 T Protein tyrosine kinase
HOFLKGFK_01195 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
HOFLKGFK_01196 1.7e-119 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HOFLKGFK_01197 6.7e-209 srtA 3.4.22.70 M Sortase family
HOFLKGFK_01198 2.6e-141 S Bacterial protein of unknown function (DUF881)
HOFLKGFK_01199 3.1e-57 crgA D Involved in cell division
HOFLKGFK_01200 3.3e-237 L ribosomal rna small subunit methyltransferase
HOFLKGFK_01201 2.8e-148 gluP 3.4.21.105 S Rhomboid family
HOFLKGFK_01202 1.5e-35
HOFLKGFK_01203 1.4e-308 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HOFLKGFK_01204 7.1e-76 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HOFLKGFK_01205 4.8e-63 I Sterol carrier protein
HOFLKGFK_01206 1.4e-41 S Protein of unknown function (DUF3073)
HOFLKGFK_01207 2.4e-181 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOFLKGFK_01208 9.4e-300 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOFLKGFK_01209 0.0 yjjP S Threonine/Serine exporter, ThrE
HOFLKGFK_01210 2.3e-311 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HOFLKGFK_01211 2.1e-210 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HOFLKGFK_01212 7e-181
HOFLKGFK_01213 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HOFLKGFK_01214 1e-240 ytfL P Transporter associated domain
HOFLKGFK_01215 2.9e-187 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HOFLKGFK_01216 3.1e-101 S Protein of unknown function DUF45
HOFLKGFK_01220 2.9e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HOFLKGFK_01221 2.9e-194 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HOFLKGFK_01222 6.1e-28 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HOFLKGFK_01223 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
HOFLKGFK_01224 1.2e-24 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOFLKGFK_01225 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOFLKGFK_01226 5.6e-206 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOFLKGFK_01227 4.4e-153 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOFLKGFK_01228 6.2e-90 S Protein of unknown function (DUF721)
HOFLKGFK_01229 8.2e-79 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOFLKGFK_01230 3.5e-146 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOFLKGFK_01231 7.1e-13 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HOFLKGFK_01232 1.8e-176 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HOFLKGFK_01233 6.6e-306 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HOFLKGFK_01234 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HOFLKGFK_01235 3e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HOFLKGFK_01236 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
HOFLKGFK_01237 8e-91 jag S Putative single-stranded nucleic acids-binding domain
HOFLKGFK_01238 1.7e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HOFLKGFK_01239 4.5e-172 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HOFLKGFK_01240 4.4e-202 parB K Belongs to the ParB family
HOFLKGFK_01241 6.9e-181 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HOFLKGFK_01242 1.4e-42 S Psort location Extracellular, score 8.82
HOFLKGFK_01244 1.4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HOFLKGFK_01245 4e-13 S Domain of unknown function (DUF4143)
HOFLKGFK_01246 9.8e-80 murJ KLT MviN-like protein
HOFLKGFK_01247 1.4e-240 murJ KLT MviN-like protein
HOFLKGFK_01248 6.2e-177 murJ KLT MviN-like protein
HOFLKGFK_01249 5e-115 murJ KLT MviN-like protein
HOFLKGFK_01250 0.0 M Conserved repeat domain
HOFLKGFK_01251 1.8e-121 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HOFLKGFK_01252 5e-284 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HOFLKGFK_01253 2.6e-109 S LytR cell envelope-related transcriptional attenuator
HOFLKGFK_01254 1.1e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HOFLKGFK_01255 7.8e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HOFLKGFK_01256 4.1e-195 S G5
HOFLKGFK_01258 5.2e-151 O Thioredoxin
HOFLKGFK_01259 0.0 KLT Protein tyrosine kinase
HOFLKGFK_01260 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
HOFLKGFK_01262 7.5e-58 S Helix-turn-helix domain
HOFLKGFK_01263 4.2e-10 S Helix-turn-helix domain
HOFLKGFK_01267 4.1e-63 ydhQ 2.7.11.1 MU cell adhesion
HOFLKGFK_01271 5e-190 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOFLKGFK_01272 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOFLKGFK_01273 3.2e-101
HOFLKGFK_01274 1.9e-242 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HOFLKGFK_01275 8.3e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOFLKGFK_01276 2.3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
HOFLKGFK_01277 7.3e-215 EGP Major facilitator Superfamily
HOFLKGFK_01278 7.3e-106 3.1.3.27 E haloacid dehalogenase-like hydrolase
HOFLKGFK_01279 1.6e-131 G Fic/DOC family
HOFLKGFK_01280 5.5e-140
HOFLKGFK_01281 5.6e-159 IQ Enoyl-(Acyl carrier protein) reductase
HOFLKGFK_01282 1.4e-84 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HOFLKGFK_01283 1.4e-75 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HOFLKGFK_01284 1.4e-95 bcp 1.11.1.15 O Redoxin
HOFLKGFK_01285 8.1e-28 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_01286 5.6e-95 S Pyridoxamine 5'-phosphate oxidase
HOFLKGFK_01287 0.0 S Histidine phosphatase superfamily (branch 2)
HOFLKGFK_01288 7.9e-44 L transposition
HOFLKGFK_01289 4.3e-23 C Acetamidase/Formamidase family
HOFLKGFK_01290 6.1e-15
HOFLKGFK_01291 2.3e-46 K helix_turn_helix gluconate operon transcriptional repressor
HOFLKGFK_01292 1.2e-74 V ATPases associated with a variety of cellular activities
HOFLKGFK_01293 1.7e-69 V ATPases associated with a variety of cellular activities
HOFLKGFK_01294 3.3e-116 S ABC-2 family transporter protein
HOFLKGFK_01295 4.4e-123 S Haloacid dehalogenase-like hydrolase
HOFLKGFK_01296 1.4e-261 recN L May be involved in recombinational repair of damaged DNA
HOFLKGFK_01297 1.1e-117 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOFLKGFK_01298 1.5e-259 trkB P Cation transport protein
HOFLKGFK_01299 6.3e-97 trkA P TrkA-N domain
HOFLKGFK_01300 1.2e-130 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HOFLKGFK_01301 2e-191 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HOFLKGFK_01302 1.5e-149 L Tetratricopeptide repeat
HOFLKGFK_01303 1.5e-36 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOFLKGFK_01304 1.1e-187 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOFLKGFK_01305 6e-121 S Protein of unknown function (DUF975)
HOFLKGFK_01306 7.5e-216 S Protein of unknown function (DUF975)
HOFLKGFK_01307 8.6e-137 S Putative ABC-transporter type IV
HOFLKGFK_01308 9.7e-94 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HOFLKGFK_01309 1.3e-279 argH 4.3.2.1 E argininosuccinate lyase
HOFLKGFK_01310 2e-140 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HOFLKGFK_01311 5e-73 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HOFLKGFK_01312 4.1e-47 argR K Regulates arginine biosynthesis genes
HOFLKGFK_01313 9.4e-185 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HOFLKGFK_01314 2.7e-241 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HOFLKGFK_01315 2.8e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HOFLKGFK_01316 6.7e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HOFLKGFK_01317 4.5e-205 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HOFLKGFK_01318 4.9e-99
HOFLKGFK_01319 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HOFLKGFK_01320 2.4e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HOFLKGFK_01322 1.5e-11 V FtsX-like permease family
HOFLKGFK_01323 1.3e-96 yvdD 3.2.2.10 S Possible lysine decarboxylase
HOFLKGFK_01325 4.5e-18
HOFLKGFK_01327 1.5e-17 L HNH endonuclease
HOFLKGFK_01328 8.3e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
HOFLKGFK_01329 4e-42 V DNA modification
HOFLKGFK_01330 8.9e-253 glnA 6.3.1.2 E glutamine synthetase
HOFLKGFK_01331 7.2e-19 glnA 6.3.1.2 E glutamine synthetase
HOFLKGFK_01332 6e-143 S Domain of unknown function (DUF4191)
HOFLKGFK_01333 8.4e-247 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HOFLKGFK_01334 3.6e-93 S Protein of unknown function (DUF3043)
HOFLKGFK_01335 2.3e-251 argE E Peptidase dimerisation domain
HOFLKGFK_01336 2.1e-113 cbiQ P Cobalt transport protein
HOFLKGFK_01337 2.3e-268 ykoD P ATPases associated with a variety of cellular activities
HOFLKGFK_01338 9.9e-85 ykoE S ABC-type cobalt transport system, permease component
HOFLKGFK_01339 1.4e-182 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HOFLKGFK_01340 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOFLKGFK_01341 0.0 S Tetratricopeptide repeat
HOFLKGFK_01342 3e-238 S Tetratricopeptide repeat
HOFLKGFK_01343 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOFLKGFK_01344 3e-42 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOFLKGFK_01345 7.3e-308 2.8.2.22 S Arylsulfotransferase Ig-like domain
HOFLKGFK_01346 5e-145 bioM P ATPases associated with a variety of cellular activities
HOFLKGFK_01347 2.4e-220 E Aminotransferase class I and II
HOFLKGFK_01348 1.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
HOFLKGFK_01349 6.3e-201 S Glycosyltransferase, group 2 family protein
HOFLKGFK_01350 1.4e-144 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HOFLKGFK_01351 2.4e-47 yhbY J CRS1_YhbY
HOFLKGFK_01352 0.0 ecfA GP ABC transporter, ATP-binding protein
HOFLKGFK_01353 6.5e-59 ecfA GP ABC transporter, ATP-binding protein
HOFLKGFK_01354 1e-108 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HOFLKGFK_01355 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
HOFLKGFK_01356 1.3e-113 kcsA U Ion channel
HOFLKGFK_01357 1.4e-184 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HOFLKGFK_01358 1.3e-84 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HOFLKGFK_01359 1.3e-122 3.2.1.8 S alpha beta
HOFLKGFK_01361 4.9e-33 S Protein of unknown function DUF262
HOFLKGFK_01362 0.0 S Protein of unknown function DUF262
HOFLKGFK_01363 8.5e-252 S AAA-like domain
HOFLKGFK_01364 4.2e-56 S SIR2-like domain
HOFLKGFK_01365 1.9e-33 3.1.21.4 V Type III restriction enzyme res subunit
HOFLKGFK_01366 4.8e-133 3.1.21.4 V Type III restriction enzyme res subunit
HOFLKGFK_01367 2.9e-187 L Eco57I restriction-modification methylase
HOFLKGFK_01368 0.0 KL Type III restriction enzyme res subunit
HOFLKGFK_01369 2.3e-130 KL Type III restriction enzyme res subunit
HOFLKGFK_01370 2.6e-131 XK26_04895
HOFLKGFK_01371 1.6e-41 lexA 3.6.4.12 K Putative DNA-binding domain
HOFLKGFK_01372 2.2e-65 S Putative inner membrane protein (DUF1819)
HOFLKGFK_01373 3.2e-22
HOFLKGFK_01374 1.5e-69
HOFLKGFK_01375 4.3e-211
HOFLKGFK_01376 1.9e-146 S phosphoesterase or phosphohydrolase
HOFLKGFK_01377 9.7e-31
HOFLKGFK_01378 1e-11 C Aldo/keto reductase family
HOFLKGFK_01380 4.8e-136 2.7.13.3 T Histidine kinase
HOFLKGFK_01381 4.2e-113 K helix_turn_helix, Lux Regulon
HOFLKGFK_01382 3.3e-310 KLT Lanthionine synthetase C-like protein
HOFLKGFK_01383 4.2e-138 3.6.3.44 V ABC transporter
HOFLKGFK_01384 1.4e-93 msbA2 3.6.3.44 V ABC transporter transmembrane region
HOFLKGFK_01385 1.5e-158 O Thioredoxin
HOFLKGFK_01386 6e-126 E Psort location Cytoplasmic, score 8.87
HOFLKGFK_01387 5e-131 yebE S DUF218 domain
HOFLKGFK_01388 1.2e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HOFLKGFK_01389 9e-237 rnd 3.1.13.5 J 3'-5' exonuclease
HOFLKGFK_01390 9.9e-80 S Protein of unknown function (DUF3000)
HOFLKGFK_01391 2.8e-165 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOFLKGFK_01392 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HOFLKGFK_01393 9.4e-22 pflB 2.3.1.54 C Pyruvate formate lyase-like
HOFLKGFK_01394 4.5e-31
HOFLKGFK_01395 7.1e-161 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HOFLKGFK_01396 2.1e-154 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HOFLKGFK_01397 1.2e-211 S Peptidase dimerisation domain
HOFLKGFK_01398 1.3e-93 metI P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01399 4.1e-147 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOFLKGFK_01400 1.9e-149 metQ P NLPA lipoprotein
HOFLKGFK_01402 1.4e-110 S Sucrose-6F-phosphate phosphohydrolase
HOFLKGFK_01403 0.0 S LPXTG-motif cell wall anchor domain protein
HOFLKGFK_01404 2.5e-245 dinF V MatE
HOFLKGFK_01405 3.5e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOFLKGFK_01406 1.2e-169 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOFLKGFK_01407 1.2e-266 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOFLKGFK_01408 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HOFLKGFK_01409 1e-47 S Domain of unknown function (DUF4193)
HOFLKGFK_01410 7e-147 S Protein of unknown function (DUF3071)
HOFLKGFK_01411 4e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
HOFLKGFK_01412 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HOFLKGFK_01413 9.5e-211 lhr L DEAD DEAH box helicase
HOFLKGFK_01414 0.0 lhr L DEAD DEAH box helicase
HOFLKGFK_01415 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
HOFLKGFK_01416 5.4e-79 S Protein of unknown function (DUF2975)
HOFLKGFK_01417 2.5e-242 T PhoQ Sensor
HOFLKGFK_01418 1.5e-222 G Major Facilitator Superfamily
HOFLKGFK_01419 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HOFLKGFK_01420 1e-172 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HOFLKGFK_01421 1.1e-118
HOFLKGFK_01422 5.9e-197 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
HOFLKGFK_01423 0.0 pknL 2.7.11.1 KLT PASTA
HOFLKGFK_01424 4.3e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
HOFLKGFK_01425 1.3e-97
HOFLKGFK_01426 3.4e-194 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOFLKGFK_01427 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HOFLKGFK_01428 1.3e-154 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HOFLKGFK_01429 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOFLKGFK_01430 3.5e-123 recX S Modulates RecA activity
HOFLKGFK_01431 5.4e-212 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOFLKGFK_01432 4.3e-46 S Protein of unknown function (DUF3046)
HOFLKGFK_01433 6.1e-80 K Helix-turn-helix XRE-family like proteins
HOFLKGFK_01434 5.5e-98 cinA 3.5.1.42 S Belongs to the CinA family
HOFLKGFK_01435 1.9e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOFLKGFK_01436 0.0 ftsK D FtsK SpoIIIE family protein
HOFLKGFK_01437 1.9e-192 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HOFLKGFK_01438 1.6e-202 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HOFLKGFK_01439 9.5e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HOFLKGFK_01440 1.6e-25 ydeD EG EamA-like transporter family
HOFLKGFK_01441 4.8e-58 ydeD EG EamA-like transporter family
HOFLKGFK_01442 1.7e-127 ybhL S Belongs to the BI1 family
HOFLKGFK_01443 1.4e-57 S Domain of unknown function (DUF5067)
HOFLKGFK_01444 1.7e-68 T Histidine kinase
HOFLKGFK_01445 1.3e-140 T Histidine kinase
HOFLKGFK_01446 1.8e-127 K helix_turn_helix, Lux Regulon
HOFLKGFK_01447 0.0 S Protein of unknown function DUF262
HOFLKGFK_01448 9e-116 K helix_turn_helix, Lux Regulon
HOFLKGFK_01449 6.9e-241 T Histidine kinase
HOFLKGFK_01450 4.4e-191 V ATPases associated with a variety of cellular activities
HOFLKGFK_01451 3.8e-224 V ABC-2 family transporter protein
HOFLKGFK_01452 9.9e-228 V ABC-2 family transporter protein
HOFLKGFK_01453 3.2e-191 rhaR1 K helix_turn_helix, arabinose operon control protein
HOFLKGFK_01454 4.7e-109 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HOFLKGFK_01455 4.9e-249 VP1224 V Psort location CytoplasmicMembrane, score 9.99
HOFLKGFK_01456 7.5e-205 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HOFLKGFK_01457 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HOFLKGFK_01458 0.0 ctpE P E1-E2 ATPase
HOFLKGFK_01459 2e-74
HOFLKGFK_01460 2.8e-243 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOFLKGFK_01461 2.4e-133 S Protein of unknown function (DUF3159)
HOFLKGFK_01462 1.7e-151 S Protein of unknown function (DUF3710)
HOFLKGFK_01463 1.4e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HOFLKGFK_01464 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
HOFLKGFK_01465 4.1e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
HOFLKGFK_01466 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01467 0.0 E ABC transporter, substrate-binding protein, family 5
HOFLKGFK_01468 4.6e-174 E ABC transporter, substrate-binding protein, family 5
HOFLKGFK_01469 1.8e-106 E ABC transporter, substrate-binding protein, family 5
HOFLKGFK_01470 6.3e-138 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HOFLKGFK_01471 4.4e-42
HOFLKGFK_01472 8.9e-195 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HOFLKGFK_01473 2.1e-148 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HOFLKGFK_01474 5.8e-28 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HOFLKGFK_01475 4e-104
HOFLKGFK_01476 0.0 typA T Elongation factor G C-terminus
HOFLKGFK_01477 1.7e-249 naiP U Sugar (and other) transporter
HOFLKGFK_01478 2.1e-151 nrtR 3.6.1.55 F NUDIX hydrolase
HOFLKGFK_01479 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HOFLKGFK_01480 2e-177 xerD D recombinase XerD
HOFLKGFK_01481 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HOFLKGFK_01482 2.1e-25 rpmI J Ribosomal protein L35
HOFLKGFK_01483 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HOFLKGFK_01484 3.7e-110 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HOFLKGFK_01485 7.7e-100 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOFLKGFK_01486 9.1e-08 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOFLKGFK_01487 2e-58 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOFLKGFK_01488 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOFLKGFK_01489 7.9e-172 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HOFLKGFK_01490 4.1e-169 galM 5.1.3.3 G Aldose 1-epimerase
HOFLKGFK_01491 4.1e-37
HOFLKGFK_01492 6.3e-97 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HOFLKGFK_01493 1e-274 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOFLKGFK_01494 3.3e-186 V Acetyltransferase (GNAT) domain
HOFLKGFK_01495 9.6e-289 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
HOFLKGFK_01496 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HOFLKGFK_01497 5.8e-94 3.6.1.55 F NUDIX domain
HOFLKGFK_01498 0.0 P Belongs to the ABC transporter superfamily
HOFLKGFK_01499 4.7e-192 dppC EP Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01500 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01501 4.7e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
HOFLKGFK_01502 1.7e-218 GK ROK family
HOFLKGFK_01503 2.9e-165 2.7.1.4 G pfkB family carbohydrate kinase
HOFLKGFK_01504 3.5e-220 S Metal-independent alpha-mannosidase (GH125)
HOFLKGFK_01505 1.6e-27
HOFLKGFK_01506 2.4e-247 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HOFLKGFK_01507 5.4e-47 ftsQ 6.3.2.4 D Cell division protein FtsQ
HOFLKGFK_01508 2.9e-84 ftsQ 6.3.2.4 D Cell division protein FtsQ
HOFLKGFK_01509 2.3e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
HOFLKGFK_01510 6.4e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HOFLKGFK_01511 8.1e-203 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HOFLKGFK_01512 3.3e-256 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HOFLKGFK_01513 8.8e-193 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOFLKGFK_01514 1.6e-200 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HOFLKGFK_01515 2.3e-46 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HOFLKGFK_01516 7.1e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOFLKGFK_01517 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HOFLKGFK_01518 4.6e-63 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HOFLKGFK_01519 1.3e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HOFLKGFK_01520 7e-92 mraZ K Belongs to the MraZ family
HOFLKGFK_01521 0.0 L DNA helicase
HOFLKGFK_01522 1.1e-217 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HOFLKGFK_01523 2.9e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOFLKGFK_01524 1e-53 M Lysin motif
HOFLKGFK_01525 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HOFLKGFK_01526 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOFLKGFK_01527 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HOFLKGFK_01528 4.9e-271 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HOFLKGFK_01529 5.9e-114 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HOFLKGFK_01530 8.8e-298 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HOFLKGFK_01531 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HOFLKGFK_01532 7.1e-171
HOFLKGFK_01533 6.1e-155 V N-Acetylmuramoyl-L-alanine amidase
HOFLKGFK_01534 9.2e-82
HOFLKGFK_01535 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HOFLKGFK_01536 8.9e-198 K helix_turn _helix lactose operon repressor
HOFLKGFK_01537 3.1e-240 mntH P H( )-stimulated, divalent metal cation uptake system
HOFLKGFK_01538 1.3e-167 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
HOFLKGFK_01539 2.6e-125 L Protein of unknown function (DUF1524)
HOFLKGFK_01540 1.9e-242 T Diguanylate cyclase (GGDEF) domain protein
HOFLKGFK_01541 6.8e-284 EGP Major facilitator Superfamily
HOFLKGFK_01542 1.3e-46
HOFLKGFK_01543 1.6e-140 S Endonuclease/Exonuclease/phosphatase family
HOFLKGFK_01544 1.7e-84 3.1.3.48 T Low molecular weight phosphatase family
HOFLKGFK_01545 9.3e-224 pflA S Protein of unknown function (DUF4012)
HOFLKGFK_01546 3.8e-191 wcoI DM Psort location CytoplasmicMembrane, score
HOFLKGFK_01548 3.4e-12
HOFLKGFK_01549 1.1e-106
HOFLKGFK_01551 4.3e-42 L PFAM Integrase catalytic
HOFLKGFK_01552 8.8e-94 L PFAM Integrase catalytic
HOFLKGFK_01553 2.9e-72 L PFAM Integrase catalytic
HOFLKGFK_01554 1.4e-38 L Transposase, Mutator family
HOFLKGFK_01555 3.6e-22 L Transposase, Mutator family
HOFLKGFK_01556 0.0 3.6.4.12 L AAA domain
HOFLKGFK_01557 0.0 L ATP-dependent endonuclease of the OLD
HOFLKGFK_01558 3.6e-10 tnp7109-21 L Integrase core domain
HOFLKGFK_01559 2.5e-15 L PFAM Integrase catalytic
HOFLKGFK_01560 3.6e-10
HOFLKGFK_01561 2.2e-48 L Integrase core domain
HOFLKGFK_01562 6.7e-273 L PFAM Integrase catalytic
HOFLKGFK_01563 7.2e-133 L IstB-like ATP binding protein
HOFLKGFK_01564 1.4e-107 3.1.3.48 T Low molecular weight phosphatase family
HOFLKGFK_01565 4.6e-114 S Psort location CytoplasmicMembrane, score 9.99
HOFLKGFK_01567 6.9e-167 rgpAc GT4 M Domain of unknown function (DUF1972)
HOFLKGFK_01568 9.3e-172 rfaG3 M Glycosyltransferase, group 1 family protein
HOFLKGFK_01569 5.3e-34 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
HOFLKGFK_01570 4.9e-33 M Glycosyltransferase like family 2
HOFLKGFK_01571 2e-17 M O-Antigen ligase
HOFLKGFK_01572 1.7e-138 S Psort location CytoplasmicMembrane, score 9.99
HOFLKGFK_01573 5.2e-119 C Polysaccharide pyruvyl transferase
HOFLKGFK_01574 3.3e-21 S Glycosyltransferase like family 2
HOFLKGFK_01575 6.2e-25 S Core-2/I-Branching enzyme
HOFLKGFK_01576 2.7e-07 L Phage integrase family
HOFLKGFK_01577 1.8e-195 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOFLKGFK_01578 2.5e-264 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HOFLKGFK_01579 5.6e-169 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HOFLKGFK_01580 2e-08
HOFLKGFK_01581 3.5e-14 O Subtilase family
HOFLKGFK_01582 1.8e-51 O Subtilase family
HOFLKGFK_01583 2.4e-10
HOFLKGFK_01584 1.7e-220 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
HOFLKGFK_01585 4.5e-151 V Abi-like protein
HOFLKGFK_01587 1.8e-53 L Helix-turn-helix domain
HOFLKGFK_01588 1.2e-67 K Helix-turn-helix domain protein
HOFLKGFK_01589 4.1e-115 V Abi-like protein
HOFLKGFK_01590 2.5e-128 K Psort location Cytoplasmic, score
HOFLKGFK_01591 7.6e-258 G Bacterial extracellular solute-binding protein
HOFLKGFK_01592 6.5e-162 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01593 6.9e-120 P Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01594 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HOFLKGFK_01595 1.7e-256 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HOFLKGFK_01597 9.2e-89
HOFLKGFK_01598 1.6e-169 S G5
HOFLKGFK_01599 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HOFLKGFK_01600 2.8e-36 F Domain of unknown function (DUF4916)
HOFLKGFK_01601 9.1e-68 F Domain of unknown function (DUF4916)
HOFLKGFK_01602 3.4e-160 mhpC I Alpha/beta hydrolase family
HOFLKGFK_01603 2.1e-207 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HOFLKGFK_01604 5.9e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HOFLKGFK_01605 3.3e-236 S Uncharacterized conserved protein (DUF2183)
HOFLKGFK_01606 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HOFLKGFK_01607 0.0 M Cna protein B-type domain
HOFLKGFK_01608 2.7e-92 amy 3.1.1.53, 3.2.1.1, 3.2.1.41 CBM48,GH13 G Alpha amylase, catalytic domain
HOFLKGFK_01609 1e-141 amy 3.1.1.53, 3.2.1.1, 3.2.1.41 CBM48,GH13 G Alpha amylase, catalytic domain
HOFLKGFK_01610 7.6e-49 DMZ Cadherin-like beta sandwich domain
HOFLKGFK_01611 6.2e-10 amy 3.1.1.53, 3.2.1.1, 3.2.1.41 CBM48,GH13 G Alpha amylase, catalytic domain
HOFLKGFK_01612 2.2e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HOFLKGFK_01613 5.8e-29 J TM2 domain
HOFLKGFK_01614 2e-216 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HOFLKGFK_01615 2.3e-133 glxR K helix_turn_helix, cAMP Regulatory protein
HOFLKGFK_01616 2e-69 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HOFLKGFK_01617 2.8e-24 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HOFLKGFK_01618 1.1e-295 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HOFLKGFK_01619 3e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
HOFLKGFK_01620 1.5e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HOFLKGFK_01621 3.4e-141 glpR K DeoR C terminal sensor domain
HOFLKGFK_01622 8.9e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HOFLKGFK_01623 4.9e-232 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HOFLKGFK_01624 1.7e-309 G Bacterial extracellular solute-binding protein
HOFLKGFK_01625 1.6e-177 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01626 1.5e-25 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01627 3.2e-130 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_01628 3.5e-115 S Protein of unknown function, DUF624
HOFLKGFK_01629 4.4e-151 K helix_turn _helix lactose operon repressor
HOFLKGFK_01630 1.6e-17 K helix_turn _helix lactose operon repressor
HOFLKGFK_01631 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HOFLKGFK_01632 5.5e-43 gcvR T Belongs to the UPF0237 family
HOFLKGFK_01633 3.6e-252 S UPF0210 protein
HOFLKGFK_01634 6.6e-110 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HOFLKGFK_01635 4.6e-174 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HOFLKGFK_01636 3.2e-92
HOFLKGFK_01637 1.1e-281 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFLKGFK_01638 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFLKGFK_01639 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFLKGFK_01640 1.6e-210 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFLKGFK_01641 1.5e-53 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFLKGFK_01642 2.8e-97 T Forkhead associated domain
HOFLKGFK_01643 4.8e-104 B Belongs to the OprB family
HOFLKGFK_01644 5.8e-163 3.1.3.16 T Sigma factor PP2C-like phosphatases
HOFLKGFK_01645 1.3e-204 E Transglutaminase-like superfamily
HOFLKGFK_01646 3e-222 E Transglutaminase-like superfamily
HOFLKGFK_01647 8.3e-221 S Protein of unknown function DUF58
HOFLKGFK_01648 1.9e-208 S ATPase family associated with various cellular activities (AAA)
HOFLKGFK_01649 0.0 S Fibronectin type 3 domain
HOFLKGFK_01650 1.8e-168 S Fibronectin type 3 domain
HOFLKGFK_01651 6.9e-52 S Fibronectin type 3 domain
HOFLKGFK_01652 9.1e-142 KLT Protein tyrosine kinase
HOFLKGFK_01653 3.4e-93 KLT Protein tyrosine kinase
HOFLKGFK_01654 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HOFLKGFK_01655 6.5e-106 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HOFLKGFK_01656 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HOFLKGFK_01657 6.6e-246 G Major Facilitator Superfamily
HOFLKGFK_01658 1.4e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HOFLKGFK_01659 1.1e-38 csoR S Metal-sensitive transcriptional repressor
HOFLKGFK_01660 0.0 pacS 3.6.3.54 P E1-E2 ATPase
HOFLKGFK_01661 3.4e-152 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOFLKGFK_01662 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOFLKGFK_01663 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
HOFLKGFK_01664 2.9e-169
HOFLKGFK_01665 0.0 O Type VII secretion system ESX-1, transport TM domain B
HOFLKGFK_01666 1e-225 snm S WXG100 protein secretion system (Wss), protein YukD
HOFLKGFK_01667 1.1e-47 esxU S Proteins of 100 residues with WXG
HOFLKGFK_01668 1.5e-43 S Proteins of 100 residues with WXG
HOFLKGFK_01671 1.1e-264 O Subtilase family
HOFLKGFK_01672 1.3e-175
HOFLKGFK_01673 9.8e-142
HOFLKGFK_01674 3.7e-188
HOFLKGFK_01675 4.4e-55
HOFLKGFK_01676 1.2e-189
HOFLKGFK_01677 1.3e-156 T Forkhead associated domain
HOFLKGFK_01678 7.7e-191 eccCa D FtsK/SpoIIIE family
HOFLKGFK_01679 0.0 eccCa D FtsK/SpoIIIE family
HOFLKGFK_01680 4.4e-112 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOFLKGFK_01681 2.9e-131 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOFLKGFK_01682 5.2e-116 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOFLKGFK_01683 5e-290 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
HOFLKGFK_01684 2.6e-27 EGP Major facilitator Superfamily
HOFLKGFK_01685 1.9e-99 EGP Major facilitator Superfamily
HOFLKGFK_01687 8.9e-71 L Phage integrase, N-terminal SAM-like domain
HOFLKGFK_01688 1.1e-26
HOFLKGFK_01689 8.1e-136 T regulation of circadian rhythm
HOFLKGFK_01690 2.4e-36 T regulation of circadian rhythm
HOFLKGFK_01691 3.8e-57 T regulation of circadian rhythm
HOFLKGFK_01692 1.1e-97 T AAA domain
HOFLKGFK_01694 3.3e-230 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HOFLKGFK_01695 5.5e-172 S Domain of unknown function (DUF4928)
HOFLKGFK_01697 6.5e-137 L HNH endonuclease
HOFLKGFK_01698 5e-173
HOFLKGFK_01699 1.8e-79
HOFLKGFK_01700 6.2e-58
HOFLKGFK_01701 2e-300 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
HOFLKGFK_01702 1e-08
HOFLKGFK_01703 1.4e-75
HOFLKGFK_01704 1.8e-204 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HOFLKGFK_01705 7.7e-77 5.4.99.9 H Flavin containing amine oxidoreductase
HOFLKGFK_01706 3.3e-130 5.4.99.9 H Flavin containing amine oxidoreductase
HOFLKGFK_01707 4.6e-36
HOFLKGFK_01708 1.6e-80 S enterobacterial common antigen metabolic process
HOFLKGFK_01709 7.7e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOFLKGFK_01710 8.2e-263 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HOFLKGFK_01711 3.6e-155 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HOFLKGFK_01712 5.5e-31 licD2 M LicD family
HOFLKGFK_01713 7e-170 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
HOFLKGFK_01714 1.4e-110 rgpC U Transport permease protein
HOFLKGFK_01715 2.4e-24 rgpF GT2,GT4 M Rhamnan synthesis protein F
HOFLKGFK_01716 1.2e-108 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
HOFLKGFK_01717 1.2e-76 rfbN GT2 M Glycosyl transferase family 2
HOFLKGFK_01718 9.9e-114 M Glycosyltransferase like family 2
HOFLKGFK_01719 1.3e-303 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HOFLKGFK_01720 4.5e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOFLKGFK_01721 2.4e-231 S AAA domain
HOFLKGFK_01722 1.8e-62
HOFLKGFK_01723 1.1e-197 K helix_turn _helix lactose operon repressor
HOFLKGFK_01724 2.8e-166 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HOFLKGFK_01725 1.6e-76 EGP Major Facilitator Superfamily
HOFLKGFK_01726 8.7e-120 EGP Major Facilitator Superfamily
HOFLKGFK_01727 5.7e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOFLKGFK_01728 1.6e-185 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOFLKGFK_01729 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HOFLKGFK_01730 1.3e-69 ssb1 L Single-stranded DNA-binding protein
HOFLKGFK_01731 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HOFLKGFK_01732 1.7e-70 rplI J Binds to the 23S rRNA
HOFLKGFK_01734 9.2e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HOFLKGFK_01735 4.2e-09 M Protein of unknown function (DUF3152)
HOFLKGFK_01736 7.5e-79 M Protein of unknown function (DUF3152)
HOFLKGFK_01737 6.3e-210 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOFLKGFK_01738 2.5e-80
HOFLKGFK_01739 7.2e-147 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HOFLKGFK_01740 1.4e-164 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HOFLKGFK_01741 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HOFLKGFK_01742 1e-132 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
HOFLKGFK_01743 7e-168 rmuC S RmuC family
HOFLKGFK_01744 2.7e-104 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOFLKGFK_01745 3.1e-133 spoU 2.1.1.185 J RNA methyltransferase TrmH family
HOFLKGFK_01746 6.2e-134 K Psort location Cytoplasmic, score
HOFLKGFK_01747 1.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOFLKGFK_01748 1.1e-286 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HOFLKGFK_01749 8.7e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOFLKGFK_01750 1e-204 2.3.1.57 J Acetyltransferase (GNAT) domain
HOFLKGFK_01751 2.1e-51 S Protein of unknown function (DUF2469)
HOFLKGFK_01752 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
HOFLKGFK_01753 1.9e-247 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HOFLKGFK_01754 1.3e-79 K helix_turn_helix ASNC type
HOFLKGFK_01755 3e-69 tyrA 5.4.99.5 E Chorismate mutase type II
HOFLKGFK_01756 0.0 S domain protein
HOFLKGFK_01757 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HOFLKGFK_01758 7.8e-288 E Bacterial extracellular solute-binding proteins, family 5 Middle
HOFLKGFK_01759 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HOFLKGFK_01760 4.9e-134 KT Transcriptional regulatory protein, C terminal
HOFLKGFK_01761 4.9e-134
HOFLKGFK_01762 6.4e-51 mntP P Probably functions as a manganese efflux pump
HOFLKGFK_01763 8e-15 mntP P Probably functions as a manganese efflux pump
HOFLKGFK_01764 3.4e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HOFLKGFK_01765 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HOFLKGFK_01766 3.5e-174 M LPXTG-motif cell wall anchor domain protein
HOFLKGFK_01767 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
HOFLKGFK_01768 3.4e-192 yfdV S Membrane transport protein
HOFLKGFK_01769 1.4e-272 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HOFLKGFK_01771 1.3e-206 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HOFLKGFK_01772 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
HOFLKGFK_01773 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOFLKGFK_01774 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HOFLKGFK_01775 1.3e-148 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOFLKGFK_01776 3.8e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HOFLKGFK_01777 3.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HOFLKGFK_01778 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HOFLKGFK_01779 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HOFLKGFK_01780 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HOFLKGFK_01781 6.8e-149 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HOFLKGFK_01782 6.2e-195
HOFLKGFK_01783 2.7e-180
HOFLKGFK_01784 7.1e-170 trxA2 O Tetratricopeptide repeat
HOFLKGFK_01785 4.7e-122 cyaA 4.6.1.1 S CYTH
HOFLKGFK_01787 2.7e-59 psp1 3.5.99.10 J Endoribonuclease L-PSP
HOFLKGFK_01788 5.7e-272 mmuP E amino acid
HOFLKGFK_01789 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HOFLKGFK_01790 2.5e-58 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HOFLKGFK_01791 1.7e-207 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HOFLKGFK_01792 1e-236 hom 1.1.1.3 E Homoserine dehydrogenase
HOFLKGFK_01793 8.5e-69 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HOFLKGFK_01794 6.3e-93 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HOFLKGFK_01795 2.4e-286 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HOFLKGFK_01796 2.1e-210 K helix_turn _helix lactose operon repressor
HOFLKGFK_01797 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HOFLKGFK_01798 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HOFLKGFK_01799 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HOFLKGFK_01800 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HOFLKGFK_01801 0.0 cydD V ABC transporter transmembrane region
HOFLKGFK_01802 0.0 cydD V ABC transporter transmembrane region
HOFLKGFK_01803 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HOFLKGFK_01804 3e-128 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HOFLKGFK_01805 9.1e-240 G Bacterial extracellular solute-binding protein
HOFLKGFK_01806 6.3e-104
HOFLKGFK_01809 2.5e-181 cat P Cation efflux family
HOFLKGFK_01810 5.3e-75 S Psort location CytoplasmicMembrane, score
HOFLKGFK_01811 2.2e-198 yxjG_1 E Psort location Cytoplasmic, score 8.87
HOFLKGFK_01812 1.9e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
HOFLKGFK_01813 4.6e-199 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HOFLKGFK_01814 6.7e-72 K MerR family regulatory protein
HOFLKGFK_01815 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
HOFLKGFK_01816 4.3e-52 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HOFLKGFK_01817 1.2e-99 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HOFLKGFK_01818 4.9e-83 yoaP E YoaP-like
HOFLKGFK_01819 7.2e-22 yoaP E YoaP-like
HOFLKGFK_01821 3.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOFLKGFK_01822 7.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
HOFLKGFK_01823 6.4e-148 yeaZ 2.3.1.234 O Glycoprotease family
HOFLKGFK_01824 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
HOFLKGFK_01825 6.5e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
HOFLKGFK_01826 0.0 comE S Competence protein
HOFLKGFK_01827 7.6e-28 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
HOFLKGFK_01828 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOFLKGFK_01829 1.3e-194 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOFLKGFK_01830 1.3e-105 ET Bacterial periplasmic substrate-binding proteins
HOFLKGFK_01831 5.7e-172 corA P CorA-like Mg2+ transporter protein
HOFLKGFK_01832 1.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HOFLKGFK_01833 1.1e-62 3.4.22.70 M Sortase family
HOFLKGFK_01834 4.6e-302 M domain protein
HOFLKGFK_01835 2.7e-70 pdxH S Pfam:Pyridox_oxidase
HOFLKGFK_01836 1.3e-232 XK27_00240 K Fic/DOC family
HOFLKGFK_01838 6.2e-117
HOFLKGFK_01839 2.5e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HOFLKGFK_01840 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HOFLKGFK_01841 2.6e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOFLKGFK_01842 3.4e-71 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOFLKGFK_01843 6.1e-108 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HOFLKGFK_01844 1.5e-45 guaB 1.1.1.205 F IMP dehydrogenase family protein
HOFLKGFK_01845 3e-154 guaB 1.1.1.205 F IMP dehydrogenase family protein
HOFLKGFK_01846 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HOFLKGFK_01847 1.1e-268 G ABC transporter substrate-binding protein
HOFLKGFK_01848 3.9e-306 fadD1 6.2.1.3 I AMP-binding enzyme
HOFLKGFK_01849 2.7e-28 fadD1 6.2.1.3 I AMP-binding enzyme
HOFLKGFK_01850 3.3e-96 M Peptidase family M23
HOFLKGFK_01851 4.3e-63
HOFLKGFK_01854 5e-125 XK27_06785 V ABC transporter
HOFLKGFK_01855 5e-254 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOFLKGFK_01856 2.9e-60 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOFLKGFK_01857 7.8e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HOFLKGFK_01858 1.4e-139 S SdpI/YhfL protein family
HOFLKGFK_01859 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
HOFLKGFK_01860 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HOFLKGFK_01861 2.6e-216 yxjG_1 E Psort location Cytoplasmic, score 8.87
HOFLKGFK_01862 5.6e-91 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOFLKGFK_01863 8.8e-109 J Acetyltransferase (GNAT) domain
HOFLKGFK_01864 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HOFLKGFK_01865 2.9e-162 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
HOFLKGFK_01866 1.2e-123 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOFLKGFK_01867 6.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HOFLKGFK_01868 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HOFLKGFK_01869 7e-178 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
HOFLKGFK_01870 1.1e-277 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HOFLKGFK_01871 6.4e-66 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HOFLKGFK_01872 1.5e-147 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HOFLKGFK_01873 1.1e-184 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HOFLKGFK_01874 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HOFLKGFK_01875 1.6e-157 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
HOFLKGFK_01876 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HOFLKGFK_01877 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
HOFLKGFK_01878 1.8e-198 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HOFLKGFK_01879 4.2e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
HOFLKGFK_01880 7.6e-249 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
HOFLKGFK_01881 2e-74
HOFLKGFK_01882 2.6e-307 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HOFLKGFK_01883 2.2e-69 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HOFLKGFK_01884 3e-201 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HOFLKGFK_01885 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HOFLKGFK_01886 3.3e-234 F Psort location CytoplasmicMembrane, score 10.00
HOFLKGFK_01887 2.1e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
HOFLKGFK_01888 1.2e-288 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
HOFLKGFK_01889 5e-145 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HOFLKGFK_01890 1.5e-233 hemN H Involved in the biosynthesis of porphyrin-containing compound
HOFLKGFK_01891 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HOFLKGFK_01892 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
HOFLKGFK_01893 1.1e-133 S UPF0126 domain
HOFLKGFK_01894 1.9e-227 ilvE 2.6.1.42 E Amino-transferase class IV
HOFLKGFK_01896 2.6e-73 K Acetyltransferase (GNAT) domain
HOFLKGFK_01897 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOFLKGFK_01898 1.4e-92 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOFLKGFK_01899 7.8e-78 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HOFLKGFK_01900 2.5e-194 S alpha beta
HOFLKGFK_01901 1.3e-25 yhjX EGP Major facilitator Superfamily
HOFLKGFK_01902 2.6e-30 EGP Major facilitator Superfamily
HOFLKGFK_01903 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HOFLKGFK_01904 3.1e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOFLKGFK_01906 7.1e-225 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOFLKGFK_01907 1.1e-179 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOFLKGFK_01908 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
HOFLKGFK_01909 1.1e-39 nrdH O Glutaredoxin
HOFLKGFK_01910 2e-120 K Bacterial regulatory proteins, tetR family
HOFLKGFK_01911 8.6e-224 G Transmembrane secretion effector
HOFLKGFK_01913 6.1e-268 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_01914 3.6e-250 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HOFLKGFK_01915 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HOFLKGFK_01916 1.3e-45 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HOFLKGFK_01917 5e-132 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HOFLKGFK_01918 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HOFLKGFK_01919 2e-29 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOFLKGFK_01920 1.7e-140 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOFLKGFK_01921 4.1e-251 corC S CBS domain
HOFLKGFK_01922 9.4e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOFLKGFK_01923 1.3e-207 phoH T PhoH-like protein
HOFLKGFK_01924 4.1e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HOFLKGFK_01925 2e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HOFLKGFK_01927 2.6e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
HOFLKGFK_01928 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HOFLKGFK_01929 2.7e-108 yitW S Iron-sulfur cluster assembly protein
HOFLKGFK_01930 2.6e-97 iscU C SUF system FeS assembly protein, NifU family
HOFLKGFK_01931 1.9e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HOFLKGFK_01932 1e-142 sufC O FeS assembly ATPase SufC
HOFLKGFK_01933 6.1e-235 sufD O FeS assembly protein SufD
HOFLKGFK_01934 1.5e-77 sufB O FeS assembly protein SufB
HOFLKGFK_01935 3.6e-202 sufB O FeS assembly protein SufB
HOFLKGFK_01936 0.0 S L,D-transpeptidase catalytic domain
HOFLKGFK_01937 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HOFLKGFK_01938 5.3e-96 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
HOFLKGFK_01939 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
HOFLKGFK_01940 8.7e-36 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
HOFLKGFK_01941 4e-254 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
HOFLKGFK_01942 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HOFLKGFK_01943 1.3e-215 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HOFLKGFK_01944 6.3e-120
HOFLKGFK_01945 1.5e-146 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_01946 6.7e-278 pepC 3.4.22.40 E Peptidase C1-like family
HOFLKGFK_01947 6.5e-105 S IMP dehydrogenase activity
HOFLKGFK_01948 2.3e-50 S IMP dehydrogenase activity
HOFLKGFK_01949 4.6e-299 ybiT S ABC transporter
HOFLKGFK_01950 4.7e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
HOFLKGFK_01951 2.8e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HOFLKGFK_01953 2e-13
HOFLKGFK_01954 6.9e-274 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_01955 4.7e-140 S Domain of unknown function (DUF4194)
HOFLKGFK_01956 0.0 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_01957 1.5e-22 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_01958 1.9e-132 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_01959 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HOFLKGFK_01960 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HOFLKGFK_01961 7.1e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
HOFLKGFK_01962 1.1e-170 rapZ S Displays ATPase and GTPase activities
HOFLKGFK_01963 1.3e-171 whiA K May be required for sporulation
HOFLKGFK_01964 1.9e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
HOFLKGFK_01965 9.6e-149 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HOFLKGFK_01966 2.4e-32 secG U Preprotein translocase SecG subunit
HOFLKGFK_01967 1.3e-162 S Sucrose-6F-phosphate phosphohydrolase
HOFLKGFK_01968 2.3e-300 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HOFLKGFK_01969 1.2e-08 pnuC H Nicotinamide mononucleotide transporter
HOFLKGFK_01970 3.5e-67 pnuC H Nicotinamide mononucleotide transporter
HOFLKGFK_01971 2.2e-36 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H ATPase kinase involved in NAD metabolism
HOFLKGFK_01972 2.6e-42 nadR H ATPase kinase involved in NAD metabolism
HOFLKGFK_01973 1.6e-88 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HOFLKGFK_01974 2.3e-72 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HOFLKGFK_01975 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
HOFLKGFK_01976 1.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HOFLKGFK_01977 8.6e-166 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HOFLKGFK_01978 4.3e-13 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HOFLKGFK_01979 2.1e-23 S Putative phage holin Dp-1
HOFLKGFK_01980 1.8e-88 M Glycosyl hydrolases family 25
HOFLKGFK_01982 2.1e-11
HOFLKGFK_01985 9.3e-27 MU outer membrane autotransporter barrel domain protein
HOFLKGFK_01986 4.5e-35
HOFLKGFK_01987 4.7e-88 L DNA integration
HOFLKGFK_01989 2.2e-21
HOFLKGFK_01992 1.2e-79 S Psort location Cytoplasmic, score
HOFLKGFK_01993 1.6e-39
HOFLKGFK_01994 9.9e-22 NT phage tail tape measure protein
HOFLKGFK_01995 5.5e-38 NT phage tail tape measure protein
HOFLKGFK_01996 7.9e-08
HOFLKGFK_01998 6.5e-27
HOFLKGFK_01999 2.1e-55
HOFLKGFK_02000 1.7e-27
HOFLKGFK_02001 3.4e-27
HOFLKGFK_02002 1.1e-30
HOFLKGFK_02003 8.7e-21
HOFLKGFK_02005 1.9e-95 xkdG S Phage capsid family
HOFLKGFK_02006 7.1e-32 xkdG S Phage capsid family
HOFLKGFK_02007 2.1e-69 S Phage portal protein
HOFLKGFK_02008 1.5e-92 S Terminase
HOFLKGFK_02009 8.5e-85 S Terminase
HOFLKGFK_02010 4.8e-10
HOFLKGFK_02012 8.6e-40 L HNH nucleases
HOFLKGFK_02016 2.8e-92
HOFLKGFK_02018 6.5e-12
HOFLKGFK_02022 1e-13
HOFLKGFK_02024 2.5e-27
HOFLKGFK_02025 3.8e-20
HOFLKGFK_02026 1e-60 L HNH endonuclease
HOFLKGFK_02028 5.3e-66
HOFLKGFK_02030 8.6e-18 recT L RecT family
HOFLKGFK_02031 3.4e-51 recT L RecT family
HOFLKGFK_02032 1.7e-110 yqaJ L YqaJ-like viral recombinase domain
HOFLKGFK_02037 9.7e-32 O prohibitin homologues
HOFLKGFK_02039 5.7e-82 K BRO family, N-terminal domain
HOFLKGFK_02043 1.5e-24
HOFLKGFK_02044 2e-38
HOFLKGFK_02046 8.9e-32 XK27_00240 K Fic/DOC family
HOFLKGFK_02047 3.6e-110 XK27_00240 K Fic/DOC family
HOFLKGFK_02048 3.2e-117 L Phage integrase family
HOFLKGFK_02049 5.1e-158 G Fructosamine kinase
HOFLKGFK_02050 2e-155 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HOFLKGFK_02051 1.6e-156 S PAC2 family
HOFLKGFK_02056 9.4e-36
HOFLKGFK_02057 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
HOFLKGFK_02058 9.7e-112 K helix_turn_helix, mercury resistance
HOFLKGFK_02059 6e-61
HOFLKGFK_02060 1e-89 pgp 3.1.3.18 S HAD-hyrolase-like
HOFLKGFK_02061 8.8e-34 pgp 3.1.3.18 S HAD-hyrolase-like
HOFLKGFK_02062 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HOFLKGFK_02063 0.0 helY L DEAD DEAH box helicase
HOFLKGFK_02064 2.1e-54
HOFLKGFK_02065 0.0 pafB K WYL domain
HOFLKGFK_02066 1.4e-264 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HOFLKGFK_02068 5.5e-48
HOFLKGFK_02069 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
HOFLKGFK_02070 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HOFLKGFK_02071 1.5e-161 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HOFLKGFK_02072 8.2e-34
HOFLKGFK_02073 2.7e-310 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HOFLKGFK_02074 1.7e-88
HOFLKGFK_02075 3.3e-134
HOFLKGFK_02076 2.6e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HOFLKGFK_02077 2.2e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HOFLKGFK_02078 3e-27 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOFLKGFK_02079 4.6e-49 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOFLKGFK_02080 1.8e-50 yajC U Preprotein translocase subunit
HOFLKGFK_02081 1.6e-199 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HOFLKGFK_02082 1e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HOFLKGFK_02083 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HOFLKGFK_02084 5.2e-128 yebC K transcriptional regulatory protein
HOFLKGFK_02085 1.8e-101 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
HOFLKGFK_02086 9.3e-83 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOFLKGFK_02087 1.5e-286 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOFLKGFK_02088 1.6e-141 S Bacterial protein of unknown function (DUF881)
HOFLKGFK_02089 4.2e-45 sbp S Protein of unknown function (DUF1290)
HOFLKGFK_02090 9.9e-172 S Bacterial protein of unknown function (DUF881)
HOFLKGFK_02091 1e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOFLKGFK_02092 3.9e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
HOFLKGFK_02093 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HOFLKGFK_02094 3.8e-32 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
HOFLKGFK_02095 4.6e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HOFLKGFK_02096 1e-162 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HOFLKGFK_02097 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HOFLKGFK_02098 8.2e-23 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HOFLKGFK_02099 2.7e-296 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOFLKGFK_02100 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HOFLKGFK_02101 3e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HOFLKGFK_02102 1.2e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HOFLKGFK_02103 8e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
HOFLKGFK_02104 5.8e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HOFLKGFK_02105 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HOFLKGFK_02107 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HOFLKGFK_02108 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
HOFLKGFK_02109 1.1e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOFLKGFK_02110 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
HOFLKGFK_02111 5.4e-121
HOFLKGFK_02112 4.6e-44
HOFLKGFK_02113 1.6e-138 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HOFLKGFK_02114 1.9e-62 S Protein of unknown function (DUF4235)
HOFLKGFK_02115 2.9e-136 G Phosphoglycerate mutase family
HOFLKGFK_02116 3.9e-259 amyE G Bacterial extracellular solute-binding protein
HOFLKGFK_02117 1.8e-294 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HOFLKGFK_02118 3.8e-42 K Periplasmic binding protein-like domain
HOFLKGFK_02119 7.5e-105 K Periplasmic binding protein-like domain
HOFLKGFK_02120 1.7e-182 K Psort location Cytoplasmic, score
HOFLKGFK_02121 4.1e-153 msmF G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_02122 1.5e-152 rafG G ABC transporter permease
HOFLKGFK_02123 7.7e-25 S Protein of unknown function, DUF624
HOFLKGFK_02124 4.4e-68 S Protein of unknown function, DUF624
HOFLKGFK_02125 9.7e-109 pepE 3.4.13.21 E Peptidase family S51
HOFLKGFK_02126 8.5e-13 S Transposon-encoded protein TnpV
HOFLKGFK_02127 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HOFLKGFK_02128 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
HOFLKGFK_02129 9.6e-173 malE G Bacterial extracellular solute-binding protein
HOFLKGFK_02130 4.4e-39 malE G Bacterial extracellular solute-binding protein
HOFLKGFK_02131 3.2e-248 malF G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_02132 7.7e-77 malG G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_02133 2.1e-73 malG G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_02134 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HOFLKGFK_02135 5.4e-144 S HAD-hyrolase-like
HOFLKGFK_02136 4e-96 traX S TraX protein
HOFLKGFK_02137 4.5e-35 traX S TraX protein
HOFLKGFK_02138 1.3e-193 K Psort location Cytoplasmic, score
HOFLKGFK_02139 1.3e-156 srtC 3.4.22.70 M Sortase family
HOFLKGFK_02140 1.1e-127 S membrane transporter protein
HOFLKGFK_02141 1.4e-53 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
HOFLKGFK_02142 1.3e-145 S Mitochondrial biogenesis AIM24
HOFLKGFK_02143 8.4e-57 dnaK O Heat shock 70 kDa protein
HOFLKGFK_02144 1.8e-268 dnaK O Heat shock 70 kDa protein
HOFLKGFK_02145 2.8e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOFLKGFK_02146 1.5e-157 dnaJ1 O DnaJ molecular chaperone homology domain
HOFLKGFK_02147 2.9e-114 hspR K transcriptional regulator, MerR family
HOFLKGFK_02148 4.3e-46
HOFLKGFK_02149 3.3e-129 S HAD hydrolase, family IA, variant 3
HOFLKGFK_02151 7.5e-52 dedA S SNARE associated Golgi protein
HOFLKGFK_02152 8.9e-41 dedA S SNARE associated Golgi protein
HOFLKGFK_02153 1.6e-17 3.2.1.78 GH26 G Glycosyl hydrolase family 26
HOFLKGFK_02154 8.8e-176 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOFLKGFK_02155 5.6e-106
HOFLKGFK_02156 4.5e-74 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOFLKGFK_02157 3e-76 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOFLKGFK_02158 1.9e-112 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOFLKGFK_02159 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HOFLKGFK_02161 4.1e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
HOFLKGFK_02162 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HOFLKGFK_02163 1.3e-261 lacS G Psort location CytoplasmicMembrane, score 10.00
HOFLKGFK_02164 1e-123 GK ROK family
HOFLKGFK_02165 4.2e-242 G Bacterial extracellular solute-binding protein
HOFLKGFK_02166 4.4e-44 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_02167 5.7e-86 G Binding-protein-dependent transport system inner membrane component
HOFLKGFK_02168 4.4e-164 G ABC transporter permease
HOFLKGFK_02169 1.9e-172 2.7.1.2 GK ROK family
HOFLKGFK_02170 8.3e-113 G Glycosyl hydrolase family 20, domain 2
HOFLKGFK_02171 1.2e-225 G Glycosyl hydrolase family 20, domain 2
HOFLKGFK_02172 2e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HOFLKGFK_02173 4.6e-215 nagA 3.5.1.25 G Amidohydrolase family
HOFLKGFK_02174 2.3e-187 lacR K Transcriptional regulator, LacI family
HOFLKGFK_02175 0.0 T Diguanylate cyclase, GGDEF domain
HOFLKGFK_02176 1.3e-251 3.2.1.14 GH18 S Carbohydrate binding domain
HOFLKGFK_02177 4.4e-228 M probably involved in cell wall
HOFLKGFK_02178 2.2e-119 M probably involved in cell wall
HOFLKGFK_02179 1.7e-38 M probably involved in cell wall
HOFLKGFK_02180 1.6e-215 M Protein of unknown function (DUF2961)
HOFLKGFK_02181 9.3e-155 I alpha/beta hydrolase fold
HOFLKGFK_02182 5e-27 S Psort location Cytoplasmic, score 8.87
HOFLKGFK_02183 1.1e-214 lipA I Hydrolase, alpha beta domain protein
HOFLKGFK_02184 1.6e-224 mdlA2 V ABC transporter
HOFLKGFK_02185 0.0 yknV V ABC transporter
HOFLKGFK_02186 8e-126
HOFLKGFK_02187 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
HOFLKGFK_02188 1.4e-223 K helix_turn _helix lactose operon repressor
HOFLKGFK_02189 8.6e-233 G Alpha galactosidase A
HOFLKGFK_02190 0.0 G Alpha-L-arabinofuranosidase C-terminus
HOFLKGFK_02191 6.5e-184 tatD L TatD related DNase
HOFLKGFK_02192 0.0 kup P Transport of potassium into the cell
HOFLKGFK_02193 2.3e-167 S Glutamine amidotransferase domain
HOFLKGFK_02194 5.6e-149 T HD domain
HOFLKGFK_02195 1.7e-157 V ABC transporter
HOFLKGFK_02196 1.3e-182 V ABC transporter permease
HOFLKGFK_02197 0.0 S Psort location CytoplasmicMembrane, score 9.99

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)