ORF_ID e_value Gene_name EC_number CAZy COGs Description
HAEALIFD_00001 8.6e-48 L Transposase
HAEALIFD_00002 5.9e-64 D MobA/MobL family
HAEALIFD_00003 1.3e-78
HAEALIFD_00005 4.3e-205 L Transposase and inactivated derivatives IS30 family
HAEALIFD_00006 2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HAEALIFD_00007 2.9e-252 V ABC-2 family transporter protein
HAEALIFD_00008 7.3e-101 V ABC-2 family transporter protein
HAEALIFD_00009 6.9e-181 V ATPases associated with a variety of cellular activities
HAEALIFD_00010 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HAEALIFD_00011 9.2e-234 T Histidine kinase
HAEALIFD_00012 3.1e-119 K helix_turn_helix, Lux Regulon
HAEALIFD_00013 1.1e-115 MA20_27875 P Protein of unknown function DUF47
HAEALIFD_00014 3.4e-189 pit P Phosphate transporter family
HAEALIFD_00015 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HAEALIFD_00016 1.1e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HAEALIFD_00019 4.4e-51
HAEALIFD_00020 1.2e-27
HAEALIFD_00021 9.9e-112 ysdA S Protein of unknown function (DUF1294)
HAEALIFD_00023 1.7e-122
HAEALIFD_00024 1e-281 XK27_07020 S Domain of unknown function (DUF1846)
HAEALIFD_00025 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HAEALIFD_00026 2.8e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAEALIFD_00027 1.2e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HAEALIFD_00028 2.9e-108 3.4.13.21 E Peptidase family S51
HAEALIFD_00029 4.2e-135 L Phage integrase family
HAEALIFD_00031 1.5e-218 ykiI
HAEALIFD_00032 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HAEALIFD_00033 1.5e-119 3.6.1.13 L NUDIX domain
HAEALIFD_00034 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HAEALIFD_00035 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAEALIFD_00036 9.2e-120 pdtaR T Response regulator receiver domain protein
HAEALIFD_00038 1.8e-110 aspA 3.6.1.13 L NUDIX domain
HAEALIFD_00039 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
HAEALIFD_00040 1.7e-179 terC P Integral membrane protein, TerC family
HAEALIFD_00041 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HAEALIFD_00042 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HAEALIFD_00043 3.3e-243 rpsA J Ribosomal protein S1
HAEALIFD_00044 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAEALIFD_00045 2.5e-173 P Zinc-uptake complex component A periplasmic
HAEALIFD_00046 2.8e-165 znuC P ATPases associated with a variety of cellular activities
HAEALIFD_00047 4.3e-139 znuB U ABC 3 transport family
HAEALIFD_00048 2.7e-82 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HAEALIFD_00049 5.1e-102 carD K CarD-like/TRCF domain
HAEALIFD_00050 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAEALIFD_00051 1.9e-127 T Response regulator receiver domain protein
HAEALIFD_00052 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAEALIFD_00053 1.4e-71 rulA 3.4.21.88 KT Peptidase S24-like
HAEALIFD_00054 9e-130 ctsW S Phosphoribosyl transferase domain
HAEALIFD_00055 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
HAEALIFD_00056 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HAEALIFD_00057 3.6e-261
HAEALIFD_00058 0.0 S Glycosyl transferase, family 2
HAEALIFD_00059 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HAEALIFD_00060 2.4e-270 K Cell envelope-related transcriptional attenuator domain
HAEALIFD_00061 0.0 D FtsK/SpoIIIE family
HAEALIFD_00062 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HAEALIFD_00063 7.3e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAEALIFD_00064 2e-142 yplQ S Haemolysin-III related
HAEALIFD_00065 1e-107
HAEALIFD_00067 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAEALIFD_00068 2.2e-72 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HAEALIFD_00069 8.8e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HAEALIFD_00070 6.8e-96
HAEALIFD_00072 8.9e-184 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HAEALIFD_00073 2e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HAEALIFD_00074 1.2e-100 divIC D Septum formation initiator
HAEALIFD_00075 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HAEALIFD_00076 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
HAEALIFD_00077 2.2e-298 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
HAEALIFD_00078 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAEALIFD_00079 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HAEALIFD_00080 1.5e-95 2.3.1.183 M Acetyltransferase (GNAT) domain
HAEALIFD_00081 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
HAEALIFD_00082 3.6e-151 GM ABC-2 type transporter
HAEALIFD_00083 2.1e-196 GM GDP-mannose 4,6 dehydratase
HAEALIFD_00084 1.8e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HAEALIFD_00087 5e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
HAEALIFD_00088 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAEALIFD_00089 2.1e-207 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAEALIFD_00090 0.0 S Uncharacterised protein family (UPF0182)
HAEALIFD_00091 2.6e-228 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
HAEALIFD_00092 7.6e-197
HAEALIFD_00093 1.9e-152 ytrE V ATPases associated with a variety of cellular activities
HAEALIFD_00094 3.4e-192 V N-Acetylmuramoyl-L-alanine amidase
HAEALIFD_00095 1.4e-259 argE E Peptidase dimerisation domain
HAEALIFD_00096 5.5e-104 S Protein of unknown function (DUF3043)
HAEALIFD_00097 5.6e-283 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAEALIFD_00098 1e-142 S Domain of unknown function (DUF4191)
HAEALIFD_00099 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
HAEALIFD_00100 4.7e-10
HAEALIFD_00102 5.5e-33 traSA D DNA segregation ATPase FtsK SpoIIIE
HAEALIFD_00106 5.2e-79 S GIY-YIG catalytic domain
HAEALIFD_00107 7.8e-33 3.1.21.4 L Recognizes the double-stranded sequence CTCGAG and cleaves after C-1
HAEALIFD_00108 6.3e-115 L DNA restriction-modification system
HAEALIFD_00109 2e-86 int L Phage integrase, N-terminal SAM-like domain
HAEALIFD_00110 8.8e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAEALIFD_00111 9.7e-211 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HAEALIFD_00112 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HAEALIFD_00113 0.0 S Tetratricopeptide repeat
HAEALIFD_00114 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAEALIFD_00115 2.6e-76 2.8.2.22 S Arylsulfotransferase Ig-like domain
HAEALIFD_00116 1.7e-137 bioM P ATPases associated with a variety of cellular activities
HAEALIFD_00117 2e-213 E Aminotransferase class I and II
HAEALIFD_00118 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
HAEALIFD_00120 4.3e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HAEALIFD_00121 0.0 ecfA GP ABC transporter, ATP-binding protein
HAEALIFD_00122 4.4e-256 EGP Major facilitator Superfamily
HAEALIFD_00124 8.5e-257 rarA L Recombination factor protein RarA
HAEALIFD_00125 0.0 L DEAD DEAH box helicase
HAEALIFD_00126 2.3e-193 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
HAEALIFD_00127 4.8e-199 gluD E Binding-protein-dependent transport system inner membrane component
HAEALIFD_00128 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
HAEALIFD_00129 4.3e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
HAEALIFD_00130 3.6e-140 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
HAEALIFD_00131 8.2e-93 S Aminoacyl-tRNA editing domain
HAEALIFD_00132 3.6e-64 K helix_turn_helix, Lux Regulon
HAEALIFD_00133 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HAEALIFD_00134 1.6e-252 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HAEALIFD_00135 1.1e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HAEALIFD_00139 0.0 clpC O ATPase family associated with various cellular activities (AAA)
HAEALIFD_00140 5.7e-183 uspA T Belongs to the universal stress protein A family
HAEALIFD_00141 3.3e-192 S Protein of unknown function (DUF3027)
HAEALIFD_00142 1e-66 cspB K 'Cold-shock' DNA-binding domain
HAEALIFD_00143 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAEALIFD_00144 1.6e-134 KT Response regulator receiver domain protein
HAEALIFD_00145 1.2e-173
HAEALIFD_00146 1.7e-10 S Proteins of 100 residues with WXG
HAEALIFD_00147 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HAEALIFD_00148 1.4e-30 cspA K 'Cold-shock' DNA-binding domain
HAEALIFD_00149 4.9e-70 S LytR cell envelope-related transcriptional attenuator
HAEALIFD_00150 4.2e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAEALIFD_00151 1.6e-197 moxR S ATPase family associated with various cellular activities (AAA)
HAEALIFD_00152 5e-179 S Protein of unknown function DUF58
HAEALIFD_00153 6.4e-94
HAEALIFD_00154 5.2e-190 S von Willebrand factor (vWF) type A domain
HAEALIFD_00155 1.6e-148 S von Willebrand factor (vWF) type A domain
HAEALIFD_00156 3.6e-74
HAEALIFD_00158 7.5e-291 S PGAP1-like protein
HAEALIFD_00159 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HAEALIFD_00160 0.0 S Lysylphosphatidylglycerol synthase TM region
HAEALIFD_00161 8.1e-42 hup L Belongs to the bacterial histone-like protein family
HAEALIFD_00162 1e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HAEALIFD_00163 4.7e-07 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HAEALIFD_00164 2.4e-158 hisN 3.1.3.25 G Inositol monophosphatase family
HAEALIFD_00165 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HAEALIFD_00166 0.0 arc O AAA ATPase forming ring-shaped complexes
HAEALIFD_00167 1.8e-136 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HAEALIFD_00168 1.3e-182 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAEALIFD_00169 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HAEALIFD_00170 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAEALIFD_00171 1.1e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAEALIFD_00172 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HAEALIFD_00173 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HAEALIFD_00174 1.1e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAEALIFD_00175 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HAEALIFD_00176 0.0 ctpE P E1-E2 ATPase
HAEALIFD_00177 6.8e-110
HAEALIFD_00178 2.2e-248 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAEALIFD_00179 6.1e-124 S Protein of unknown function (DUF3159)
HAEALIFD_00180 2.1e-138 S Protein of unknown function (DUF3710)
HAEALIFD_00181 3.7e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HAEALIFD_00182 5.2e-262 pepC 3.4.22.40 E Peptidase C1-like family
HAEALIFD_00183 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HAEALIFD_00184 0.0 oppD P Belongs to the ABC transporter superfamily
HAEALIFD_00185 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
HAEALIFD_00186 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
HAEALIFD_00187 4.7e-185 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HAEALIFD_00188 7.3e-42
HAEALIFD_00189 3.2e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HAEALIFD_00190 3.8e-198 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HAEALIFD_00191 6.4e-80
HAEALIFD_00192 0.0 typA T Elongation factor G C-terminus
HAEALIFD_00193 3.4e-236 iscS1 2.8.1.7 E Aminotransferase class-V
HAEALIFD_00194 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
HAEALIFD_00195 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HAEALIFD_00196 2.8e-251 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HAEALIFD_00197 1.1e-149 nrtR 3.6.1.55 F NUDIX hydrolase
HAEALIFD_00198 5.4e-113 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAEALIFD_00199 1.2e-149 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAEALIFD_00200 7e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HAEALIFD_00201 9.2e-178 xerD D recombinase XerD
HAEALIFD_00202 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HAEALIFD_00203 2.1e-25 rpmI J Ribosomal protein L35
HAEALIFD_00204 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAEALIFD_00206 2.3e-08 S Spermine/spermidine synthase domain
HAEALIFD_00207 2.2e-131 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HAEALIFD_00208 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAEALIFD_00209 2.4e-68 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAEALIFD_00210 1.3e-179 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAEALIFD_00211 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
HAEALIFD_00212 2e-64
HAEALIFD_00213 6.2e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HAEALIFD_00214 3.1e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAEALIFD_00215 9.8e-191 V Acetyltransferase (GNAT) domain
HAEALIFD_00216 2.9e-229 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
HAEALIFD_00217 2.8e-243 yxbA 6.3.1.12 S ATP-grasp
HAEALIFD_00218 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HAEALIFD_00219 0.0 smc D Required for chromosome condensation and partitioning
HAEALIFD_00220 8e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
HAEALIFD_00222 4.3e-97 3.6.1.55 F NUDIX domain
HAEALIFD_00223 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HAEALIFD_00224 0.0 P Belongs to the ABC transporter superfamily
HAEALIFD_00225 1.5e-190 dppC EP Binding-protein-dependent transport system inner membrane component
HAEALIFD_00226 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
HAEALIFD_00227 7.4e-305 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
HAEALIFD_00228 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
HAEALIFD_00229 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAEALIFD_00230 3.5e-216 GK ROK family
HAEALIFD_00231 9.9e-132 cutC P Participates in the control of copper homeostasis
HAEALIFD_00232 1.3e-224 GK ROK family
HAEALIFD_00233 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
HAEALIFD_00234 2.9e-235 G Major Facilitator Superfamily
HAEALIFD_00235 1e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HAEALIFD_00237 4.9e-37
HAEALIFD_00238 4.7e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
HAEALIFD_00239 2e-294 murC 6.3.2.8 M Belongs to the MurCDEF family
HAEALIFD_00240 2.1e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAEALIFD_00241 4.3e-226 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HAEALIFD_00242 2.5e-264 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HAEALIFD_00243 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAEALIFD_00244 2e-283 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HAEALIFD_00245 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAEALIFD_00246 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HAEALIFD_00247 9.7e-64 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HAEALIFD_00248 9.2e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HAEALIFD_00249 1.3e-90 mraZ K Belongs to the MraZ family
HAEALIFD_00250 0.0 L DNA helicase
HAEALIFD_00251 6.4e-229 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HAEALIFD_00252 8.8e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HAEALIFD_00253 1.1e-49 M Lysin motif
HAEALIFD_00254 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HAEALIFD_00255 2.8e-163 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAEALIFD_00256 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HAEALIFD_00257 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAEALIFD_00258 3.9e-173
HAEALIFD_00259 2.4e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HAEALIFD_00260 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HAEALIFD_00261 3e-174 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HAEALIFD_00262 2.9e-39 EGP Major facilitator Superfamily
HAEALIFD_00263 4e-243 S Domain of unknown function (DUF5067)
HAEALIFD_00264 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
HAEALIFD_00265 4.9e-284 S Uncharacterized protein conserved in bacteria (DUF2252)
HAEALIFD_00266 1.7e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HAEALIFD_00267 4.8e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HAEALIFD_00268 1.3e-112
HAEALIFD_00269 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HAEALIFD_00270 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HAEALIFD_00271 2.5e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HAEALIFD_00272 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAEALIFD_00273 3.9e-07 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HAEALIFD_00275 1.2e-76 yneG S Domain of unknown function (DUF4186)
HAEALIFD_00276 5.1e-170 dkgA 1.1.1.346 C Aldo/keto reductase family
HAEALIFD_00277 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
HAEALIFD_00278 1.3e-201 K WYL domain
HAEALIFD_00280 0.0 4.2.1.53 S MCRA family
HAEALIFD_00281 1.6e-46 yhbY J CRS1_YhbY
HAEALIFD_00282 7.6e-106 S zinc-ribbon domain
HAEALIFD_00283 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HAEALIFD_00284 8.8e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HAEALIFD_00285 1.7e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HAEALIFD_00286 5.1e-192 ywqG S Domain of unknown function (DUF1963)
HAEALIFD_00287 1.5e-154 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAEALIFD_00288 1.3e-142 recO L Involved in DNA repair and RecF pathway recombination
HAEALIFD_00289 1.2e-291 I acetylesterase activity
HAEALIFD_00290 4.7e-236 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HAEALIFD_00291 5.2e-223 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HAEALIFD_00292 9.7e-201 2.7.11.1 NU Tfp pilus assembly protein FimV
HAEALIFD_00294 3.3e-23
HAEALIFD_00295 5.7e-19
HAEALIFD_00296 1.8e-144 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HAEALIFD_00297 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HAEALIFD_00298 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
HAEALIFD_00299 9.2e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HAEALIFD_00300 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
HAEALIFD_00301 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HAEALIFD_00302 1.5e-146 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HAEALIFD_00303 6e-63
HAEALIFD_00305 1.3e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HAEALIFD_00306 1.2e-102 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAEALIFD_00307 9.7e-90 3.1.21.3 V DivIVA protein
HAEALIFD_00308 1.1e-41 yggT S YGGT family
HAEALIFD_00309 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HAEALIFD_00310 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAEALIFD_00311 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAEALIFD_00312 7.9e-301 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HAEALIFD_00313 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
HAEALIFD_00314 4e-159 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HAEALIFD_00315 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAEALIFD_00316 1.3e-84
HAEALIFD_00317 6.9e-231 O AAA domain (Cdc48 subfamily)
HAEALIFD_00318 5.4e-164 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HAEALIFD_00319 1.2e-61 S Thiamine-binding protein
HAEALIFD_00320 2.4e-195 K helix_turn _helix lactose operon repressor
HAEALIFD_00321 5.7e-47 S Protein of unknown function (DUF3052)
HAEALIFD_00322 8.4e-151 lon T Belongs to the peptidase S16 family
HAEALIFD_00323 1.2e-288 S Zincin-like metallopeptidase
HAEALIFD_00324 9.9e-280 uvrD2 3.6.4.12 L DNA helicase
HAEALIFD_00325 2.7e-237 mphA S Aminoglycoside phosphotransferase
HAEALIFD_00326 6.1e-32 S Protein of unknown function (DUF3107)
HAEALIFD_00327 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
HAEALIFD_00328 1.4e-113 S Vitamin K epoxide reductase
HAEALIFD_00329 7.3e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HAEALIFD_00330 9.5e-152 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HAEALIFD_00331 1.5e-167 S Patatin-like phospholipase
HAEALIFD_00332 0.0 V ABC transporter transmembrane region
HAEALIFD_00333 0.0 V ABC transporter, ATP-binding protein
HAEALIFD_00334 6.5e-100 K MarR family
HAEALIFD_00335 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
HAEALIFD_00336 2e-257 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
HAEALIFD_00337 8.4e-165
HAEALIFD_00338 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HAEALIFD_00340 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAEALIFD_00341 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HAEALIFD_00342 5.5e-272 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAEALIFD_00343 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAEALIFD_00344 9.5e-172 S Endonuclease/Exonuclease/phosphatase family
HAEALIFD_00346 4e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HAEALIFD_00347 2.4e-256 cdr OP Sulfurtransferase TusA
HAEALIFD_00348 2.6e-149 moeB 2.7.7.80 H ThiF family
HAEALIFD_00349 5.4e-133 tmp1 S Domain of unknown function (DUF4391)
HAEALIFD_00350 7.6e-49 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HAEALIFD_00351 2.9e-229 aspB E Aminotransferase class-V
HAEALIFD_00352 2.2e-125 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HAEALIFD_00353 3.6e-271 S zinc finger
HAEALIFD_00354 2.6e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAEALIFD_00355 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAEALIFD_00356 1.3e-286 O Subtilase family
HAEALIFD_00357 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
HAEALIFD_00358 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAEALIFD_00359 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAEALIFD_00360 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HAEALIFD_00361 1.6e-34 L Transposase
HAEALIFD_00362 6.4e-24 relB L RelB antitoxin
HAEALIFD_00363 1.9e-28 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HAEALIFD_00364 1.7e-66 gsiA P ATPase activity
HAEALIFD_00365 1.6e-255 G Major Facilitator Superfamily
HAEALIFD_00366 7.4e-134 K -acetyltransferase
HAEALIFD_00367 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HAEALIFD_00368 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HAEALIFD_00369 5.2e-270 KLT Protein tyrosine kinase
HAEALIFD_00370 0.0 S Fibronectin type 3 domain
HAEALIFD_00371 1.4e-229 S ATPase family associated with various cellular activities (AAA)
HAEALIFD_00372 1.9e-226 S Protein of unknown function DUF58
HAEALIFD_00373 0.0 E Transglutaminase-like superfamily
HAEALIFD_00374 3.7e-165 3.1.3.16 T Sigma factor PP2C-like phosphatases
HAEALIFD_00375 1.1e-67 B Belongs to the OprB family
HAEALIFD_00376 1.4e-95 T Forkhead associated domain
HAEALIFD_00377 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAEALIFD_00378 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAEALIFD_00379 2.8e-101
HAEALIFD_00380 3.9e-184 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HAEALIFD_00381 1.2e-60 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
HAEALIFD_00382 1.8e-121 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HAEALIFD_00383 4.2e-44
HAEALIFD_00384 9.4e-253 S UPF0210 protein
HAEALIFD_00385 4.2e-43 gcvR T Belongs to the UPF0237 family
HAEALIFD_00386 8.6e-243 EGP Sugar (and other) transporter
HAEALIFD_00387 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HAEALIFD_00388 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HAEALIFD_00389 8e-144 glpR K DeoR C terminal sensor domain
HAEALIFD_00390 1.3e-226 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HAEALIFD_00391 4.8e-218 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
HAEALIFD_00392 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HAEALIFD_00393 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
HAEALIFD_00394 1.6e-235 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HAEALIFD_00395 2e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HAEALIFD_00396 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HAEALIFD_00397 1.1e-240 S Uncharacterized conserved protein (DUF2183)
HAEALIFD_00398 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HAEALIFD_00399 0.0 enhA_2 S L,D-transpeptidase catalytic domain
HAEALIFD_00400 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HAEALIFD_00401 2.9e-124 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HAEALIFD_00402 3.4e-160 mhpC I Alpha/beta hydrolase family
HAEALIFD_00403 1.5e-117 F Domain of unknown function (DUF4916)
HAEALIFD_00404 1.9e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HAEALIFD_00405 1.3e-179 S G5
HAEALIFD_00406 2e-217
HAEALIFD_00408 5.4e-104 K cell envelope-related transcriptional attenuator
HAEALIFD_00409 1.4e-12 L Transposase
HAEALIFD_00411 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HAEALIFD_00412 1.8e-238 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HAEALIFD_00413 0.0 cadA P E1-E2 ATPase
HAEALIFD_00414 1.2e-271 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HAEALIFD_00415 9.9e-169 htpX O Belongs to the peptidase M48B family
HAEALIFD_00417 6.1e-310 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HAEALIFD_00418 1.5e-39 S Bacterial mobilisation protein (MobC)
HAEALIFD_00419 2.3e-127 S Domain of unknown function (DUF4417)
HAEALIFD_00420 6.3e-66 S Psort location Cytoplasmic, score 8.87
HAEALIFD_00421 4.5e-09
HAEALIFD_00422 1.6e-41 L Integrase core domain protein
HAEALIFD_00423 2.8e-201 1.1.1.22 M UDP binding domain
HAEALIFD_00424 5.4e-192 M Glycosyltransferase like family 2
HAEALIFD_00425 0.0 rgpF M Rhamnan synthesis protein F
HAEALIFD_00426 1.2e-293 S Tetratricopeptide repeat
HAEALIFD_00427 1.3e-208 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
HAEALIFD_00428 8.7e-131 rgpC U Transport permease protein
HAEALIFD_00429 1.2e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HAEALIFD_00430 2.3e-109 EGP Transmembrane secretion effector
HAEALIFD_00431 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
HAEALIFD_00432 5e-11
HAEALIFD_00433 4.4e-17 yccF S Inner membrane component domain
HAEALIFD_00434 1.3e-257 S Domain of unknown function (DUF4143)
HAEALIFD_00435 1.4e-161 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
HAEALIFD_00436 4.4e-111
HAEALIFD_00437 2.8e-164 tnp7109-2 L PFAM Transposase, Mutator family
HAEALIFD_00438 6.9e-155 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
HAEALIFD_00439 4e-251 L PFAM Integrase catalytic
HAEALIFD_00440 3e-228 2.7.7.7 L Transposase and inactivated derivatives
HAEALIFD_00441 1.3e-28 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HAEALIFD_00442 7.8e-29 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HAEALIFD_00443 5.9e-92
HAEALIFD_00444 6.3e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HAEALIFD_00445 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAEALIFD_00447 2.6e-152 cpaE D bacterial-type flagellum organization
HAEALIFD_00448 1.7e-190 cpaF U Type II IV secretion system protein
HAEALIFD_00449 5.7e-121 U Type ii secretion system
HAEALIFD_00450 1.7e-15 gspF NU Type II secretion system (T2SS), protein F
HAEALIFD_00451 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
HAEALIFD_00452 3.2e-41 S Protein of unknown function (DUF4244)
HAEALIFD_00453 4.8e-55 U TadE-like protein
HAEALIFD_00454 2e-56 S TIGRFAM helicase secretion neighborhood TadE-like protein
HAEALIFD_00455 3.7e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
HAEALIFD_00456 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HAEALIFD_00457 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAEALIFD_00458 9e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HAEALIFD_00459 4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
HAEALIFD_00461 1.3e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAEALIFD_00462 1.7e-116
HAEALIFD_00463 5.1e-279 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HAEALIFD_00464 4.8e-25 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HAEALIFD_00465 5.1e-278 S Calcineurin-like phosphoesterase
HAEALIFD_00466 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HAEALIFD_00467 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HAEALIFD_00469 9.3e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
HAEALIFD_00470 2.1e-123 yplQ S Haemolysin-III related
HAEALIFD_00471 0.0 vpr M PA domain
HAEALIFD_00472 2.3e-188 3.6.1.27 I PAP2 superfamily
HAEALIFD_00473 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAEALIFD_00474 1.1e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAEALIFD_00475 7e-212 holB 2.7.7.7 L DNA polymerase III
HAEALIFD_00476 4.4e-200 K helix_turn _helix lactose operon repressor
HAEALIFD_00477 5e-38 ptsH G PTS HPr component phosphorylation site
HAEALIFD_00478 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAEALIFD_00479 8.5e-124 S Fic/DOC family
HAEALIFD_00480 1e-198 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAEALIFD_00481 2.3e-09 G MFS/sugar transport protein
HAEALIFD_00482 1.2e-305 efeU_1 P Iron permease FTR1 family
HAEALIFD_00483 5.4e-108 tpd P Fe2+ transport protein
HAEALIFD_00484 2.1e-233 S Predicted membrane protein (DUF2318)
HAEALIFD_00485 9.7e-223 macB_2 V ABC transporter permease
HAEALIFD_00486 2.9e-200 Z012_06715 V FtsX-like permease family
HAEALIFD_00487 3.7e-148 macB V ABC transporter, ATP-binding protein
HAEALIFD_00488 1.9e-69 S FMN_bind
HAEALIFD_00489 2.9e-128 yydK K UTRA
HAEALIFD_00490 6.9e-09 S haloacid dehalogenase-like hydrolase
HAEALIFD_00491 1.8e-15 S haloacid dehalogenase-like hydrolase
HAEALIFD_00492 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAEALIFD_00493 4.3e-49 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HAEALIFD_00494 6.2e-41 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HAEALIFD_00495 8.3e-292 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
HAEALIFD_00496 7.6e-33 Q phosphatase activity
HAEALIFD_00497 2e-80
HAEALIFD_00498 8.9e-237 S Putative ABC-transporter type IV
HAEALIFD_00499 2.1e-162 S Sucrose-6F-phosphate phosphohydrolase
HAEALIFD_00500 5.1e-09 S Sucrose-6F-phosphate phosphohydrolase
HAEALIFD_00502 7.6e-180 3.4.22.70 M Sortase family
HAEALIFD_00503 2.3e-212 M chlorophyll binding
HAEALIFD_00504 5.1e-196 M chlorophyll binding
HAEALIFD_00505 5e-288 M LPXTG cell wall anchor motif
HAEALIFD_00506 1.7e-14
HAEALIFD_00507 1.7e-81 K Winged helix DNA-binding domain
HAEALIFD_00508 5.9e-300 V ABC transporter, ATP-binding protein
HAEALIFD_00509 0.0 V ABC transporter transmembrane region
HAEALIFD_00510 4e-83
HAEALIFD_00511 3.7e-67 XK26_04485 P Cobalt transport protein
HAEALIFD_00512 2.1e-301 pepD E Peptidase family C69
HAEALIFD_00513 0.0 S Glycosyl hydrolases related to GH101 family, GH129
HAEALIFD_00514 8e-196 XK27_01805 M Glycosyltransferase like family 2
HAEALIFD_00515 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
HAEALIFD_00517 3.4e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HAEALIFD_00518 3.4e-220 amt U Ammonium Transporter Family
HAEALIFD_00519 1e-54 glnB K Nitrogen regulatory protein P-II
HAEALIFD_00520 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HAEALIFD_00521 1e-19 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HAEALIFD_00522 4.7e-247 dinF V MatE
HAEALIFD_00523 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HAEALIFD_00524 2.5e-281 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HAEALIFD_00525 2.2e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HAEALIFD_00526 4.8e-08 S granule-associated protein
HAEALIFD_00527 0.0 ubiB S ABC1 family
HAEALIFD_00528 0.0 pacS 3.6.3.54 P E1-E2 ATPase
HAEALIFD_00529 9.6e-43 csoR S Metal-sensitive transcriptional repressor
HAEALIFD_00530 4.2e-213 rmuC S RmuC family
HAEALIFD_00531 1.1e-127 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAEALIFD_00532 1.7e-157 spoU 2.1.1.185 J RNA methyltransferase TrmH family
HAEALIFD_00533 6.2e-39 V ABC transporter
HAEALIFD_00534 4.2e-60 V ABC transporter
HAEALIFD_00535 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAEALIFD_00536 6.4e-290 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HAEALIFD_00537 1.9e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAEALIFD_00538 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
HAEALIFD_00539 3.3e-52 S Protein of unknown function (DUF2469)
HAEALIFD_00540 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
HAEALIFD_00541 3.5e-310 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAEALIFD_00542 3e-234 E Aminotransferase class I and II
HAEALIFD_00543 1.5e-89 lrp_3 K helix_turn_helix ASNC type
HAEALIFD_00544 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
HAEALIFD_00545 0.0 S domain protein
HAEALIFD_00546 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HAEALIFD_00547 7.4e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
HAEALIFD_00548 1.9e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAEALIFD_00549 2e-135 KT Transcriptional regulatory protein, C terminal
HAEALIFD_00550 1.4e-125
HAEALIFD_00551 4.2e-101 mntP P Probably functions as a manganese efflux pump
HAEALIFD_00553 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HAEALIFD_00554 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HAEALIFD_00555 0.0 K RNA polymerase II activating transcription factor binding
HAEALIFD_00556 3.9e-44
HAEALIFD_00558 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAEALIFD_00559 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
HAEALIFD_00561 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAEALIFD_00562 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAEALIFD_00563 5.3e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAEALIFD_00564 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAEALIFD_00565 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAEALIFD_00566 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAEALIFD_00567 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HAEALIFD_00568 9.5e-132 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HAEALIFD_00569 5.9e-146 QT PucR C-terminal helix-turn-helix domain
HAEALIFD_00570 0.0
HAEALIFD_00571 5.4e-150 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HAEALIFD_00572 4.2e-93 bioY S BioY family
HAEALIFD_00573 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HAEALIFD_00574 3.6e-307 pccB I Carboxyl transferase domain
HAEALIFD_00575 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HAEALIFD_00576 3.8e-99 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HAEALIFD_00577 3.9e-159 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HAEALIFD_00579 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
HAEALIFD_00580 8.9e-119
HAEALIFD_00581 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAEALIFD_00582 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HAEALIFD_00583 1.1e-97 xylR K purine nucleotide biosynthetic process
HAEALIFD_00584 1.5e-87 lemA S LemA family
HAEALIFD_00585 0.0 S Predicted membrane protein (DUF2207)
HAEALIFD_00586 1e-73 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HAEALIFD_00587 1.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAEALIFD_00589 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAEALIFD_00590 2.8e-97 nrdI F Probably involved in ribonucleotide reductase function
HAEALIFD_00591 2.2e-41 nrdH O Glutaredoxin
HAEALIFD_00592 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HAEALIFD_00593 1.2e-91 L Transposase and inactivated derivatives IS30 family
HAEALIFD_00594 0.0 yegQ O Peptidase family U32 C-terminal domain
HAEALIFD_00595 7.1e-189 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HAEALIFD_00596 1.1e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HAEALIFD_00597 3e-127 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HAEALIFD_00598 2.8e-48 D nuclear chromosome segregation
HAEALIFD_00599 2.7e-268 pepC 3.4.22.40 E Peptidase C1-like family
HAEALIFD_00600 1.1e-163 L Excalibur calcium-binding domain
HAEALIFD_00601 4.3e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAEALIFD_00602 9.9e-242 EGP Major facilitator Superfamily
HAEALIFD_00603 3.5e-106 K helix_turn_helix, Arsenical Resistance Operon Repressor
HAEALIFD_00604 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAEALIFD_00605 4.3e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HAEALIFD_00606 3.7e-241 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HAEALIFD_00607 3.7e-128 KT Transcriptional regulatory protein, C terminal
HAEALIFD_00608 1.3e-170 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HAEALIFD_00609 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
HAEALIFD_00610 3.1e-179 pstA P Phosphate transport system permease
HAEALIFD_00611 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAEALIFD_00612 4.8e-147 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAEALIFD_00613 8.8e-222 pbuO S Permease family
HAEALIFD_00616 9.1e-184 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
HAEALIFD_00617 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAEALIFD_00618 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HAEALIFD_00620 5.5e-239 T Forkhead associated domain
HAEALIFD_00621 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HAEALIFD_00622 2.8e-41
HAEALIFD_00623 5.6e-110 flgA NO SAF
HAEALIFD_00624 3.2e-38 fmdB S Putative regulatory protein
HAEALIFD_00625 5.4e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HAEALIFD_00626 2.3e-92 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
HAEALIFD_00627 2.4e-139
HAEALIFD_00628 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAEALIFD_00629 3.1e-128 bla1 3.5.2.6 V Beta-lactamase enzyme family
HAEALIFD_00630 5.4e-54 KLT Associated with various cellular activities
HAEALIFD_00634 1.9e-25 rpmG J Ribosomal protein L33
HAEALIFD_00635 1.5e-214 murB 1.3.1.98 M Cell wall formation
HAEALIFD_00636 9e-61 fdxA C 4Fe-4S binding domain
HAEALIFD_00637 1.4e-225 dapC E Aminotransferase class I and II
HAEALIFD_00638 6e-241 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAEALIFD_00640 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
HAEALIFD_00641 1.1e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HAEALIFD_00642 3.3e-119
HAEALIFD_00643 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HAEALIFD_00644 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAEALIFD_00645 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
HAEALIFD_00646 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HAEALIFD_00647 1.4e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HAEALIFD_00648 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HAEALIFD_00649 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HAEALIFD_00650 1.9e-111 ywiC S YwiC-like protein
HAEALIFD_00651 3e-14 ywiC S YwiC-like protein
HAEALIFD_00652 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
HAEALIFD_00653 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAEALIFD_00654 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
HAEALIFD_00655 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HAEALIFD_00656 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAEALIFD_00657 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAEALIFD_00658 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAEALIFD_00659 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAEALIFD_00660 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAEALIFD_00661 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
HAEALIFD_00662 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAEALIFD_00663 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAEALIFD_00664 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAEALIFD_00665 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAEALIFD_00666 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAEALIFD_00667 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAEALIFD_00668 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAEALIFD_00669 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAEALIFD_00670 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAEALIFD_00671 1e-24 rpmD J Ribosomal protein L30p/L7e
HAEALIFD_00672 2.7e-63 rplO J binds to the 23S rRNA
HAEALIFD_00673 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HAEALIFD_00674 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HAEALIFD_00675 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAEALIFD_00676 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HAEALIFD_00677 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAEALIFD_00678 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAEALIFD_00679 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAEALIFD_00680 2.8e-64 rplQ J Ribosomal protein L17
HAEALIFD_00681 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
HAEALIFD_00682 6.4e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HAEALIFD_00683 0.0 gcs2 S A circularly permuted ATPgrasp
HAEALIFD_00684 2.9e-153 E Transglutaminase/protease-like homologues
HAEALIFD_00686 7.5e-131 L Transposase and inactivated derivatives
HAEALIFD_00687 1.3e-163
HAEALIFD_00688 2.8e-188 nusA K Participates in both transcription termination and antitermination
HAEALIFD_00689 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAEALIFD_00690 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAEALIFD_00691 1.4e-237 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAEALIFD_00692 3.2e-231 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HAEALIFD_00693 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HAEALIFD_00694 1.2e-106
HAEALIFD_00696 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HAEALIFD_00697 3.2e-203 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAEALIFD_00698 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
HAEALIFD_00699 4.1e-259 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAEALIFD_00700 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HAEALIFD_00702 2.7e-43 M Spy0128-like isopeptide containing domain
HAEALIFD_00703 1.3e-41 M Spy0128-like isopeptide containing domain
HAEALIFD_00704 0.0 crr G pts system, glucose-specific IIABC component
HAEALIFD_00705 3.2e-150 arbG K CAT RNA binding domain
HAEALIFD_00706 2.3e-212 I Diacylglycerol kinase catalytic domain
HAEALIFD_00707 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
HAEALIFD_00708 2.4e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAEALIFD_00710 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
HAEALIFD_00712 5.3e-95
HAEALIFD_00713 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAEALIFD_00714 1.7e-182 opcA G Glucose-6-phosphate dehydrogenase subunit
HAEALIFD_00715 6.6e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HAEALIFD_00716 4.5e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAEALIFD_00717 8.3e-126 degU K helix_turn_helix, Lux Regulon
HAEALIFD_00718 6.4e-271 tcsS3 KT PspC domain
HAEALIFD_00719 1.1e-293 pspC KT PspC domain
HAEALIFD_00720 1.7e-131
HAEALIFD_00721 3.6e-111 S Protein of unknown function (DUF4125)
HAEALIFD_00722 0.0 S Domain of unknown function (DUF4037)
HAEALIFD_00723 1.2e-216 araJ EGP Major facilitator Superfamily
HAEALIFD_00725 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HAEALIFD_00726 6.2e-174 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HAEALIFD_00727 1.4e-147 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAEALIFD_00728 1e-09 EGP Major facilitator Superfamily
HAEALIFD_00729 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
HAEALIFD_00730 1.7e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAEALIFD_00731 2.6e-39
HAEALIFD_00732 8.5e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HAEALIFD_00733 8e-180 usp 3.5.1.28 CBM50 S CHAP domain
HAEALIFD_00734 2.1e-106 M NlpC/P60 family
HAEALIFD_00735 1.6e-191 T Universal stress protein family
HAEALIFD_00736 3.8e-72 attW O OsmC-like protein
HAEALIFD_00737 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAEALIFD_00738 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
HAEALIFD_00739 5.2e-95 ptpA 3.1.3.48 T low molecular weight
HAEALIFD_00740 2.2e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
HAEALIFD_00741 8.2e-38 azlD E Branched-chain amino acid transport protein (AzlD)
HAEALIFD_00742 1.3e-111 vex2 V ABC transporter, ATP-binding protein
HAEALIFD_00743 3.2e-212 vex1 V Efflux ABC transporter, permease protein
HAEALIFD_00744 4.7e-220 vex3 V ABC transporter permease
HAEALIFD_00746 6.6e-172
HAEALIFD_00747 7.4e-109 ytrE V ABC transporter
HAEALIFD_00748 1.5e-178 V N-Acetylmuramoyl-L-alanine amidase
HAEALIFD_00749 4.8e-101
HAEALIFD_00750 3.9e-119 K Transcriptional regulatory protein, C terminal
HAEALIFD_00751 3.8e-227 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HAEALIFD_00752 3.5e-180 lacR K Transcriptional regulator, LacI family
HAEALIFD_00753 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
HAEALIFD_00754 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HAEALIFD_00755 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
HAEALIFD_00757 4.8e-176 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HAEALIFD_00758 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HAEALIFD_00759 2.6e-68 S Domain of unknown function (DUF4190)
HAEALIFD_00762 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
HAEALIFD_00763 4.3e-177 3.4.14.13 M Glycosyltransferase like family 2
HAEALIFD_00764 9.6e-273 S AI-2E family transporter
HAEALIFD_00765 1.3e-232 epsG M Glycosyl transferase family 21
HAEALIFD_00766 1.7e-168 natA V ATPases associated with a variety of cellular activities
HAEALIFD_00767 2.5e-308
HAEALIFD_00768 8.5e-260 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
HAEALIFD_00769 2.3e-212 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HAEALIFD_00770 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HAEALIFD_00771 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAEALIFD_00772 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HAEALIFD_00773 2.3e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HAEALIFD_00774 2.1e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAEALIFD_00775 1.3e-77 S Protein of unknown function (DUF3180)
HAEALIFD_00776 2.1e-171 tesB I Thioesterase-like superfamily
HAEALIFD_00777 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
HAEALIFD_00778 5.3e-306 yjjK S ATP-binding cassette protein, ChvD family
HAEALIFD_00780 9.6e-54 M domain, Protein
HAEALIFD_00781 5.7e-126
HAEALIFD_00783 4.4e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HAEALIFD_00784 9.1e-16 S Protein of unknown function (DUF979)
HAEALIFD_00785 7.5e-49 S DUF218 domain
HAEALIFD_00787 7.9e-114 S Pyridoxamine 5'-phosphate oxidase
HAEALIFD_00788 1.4e-158 I alpha/beta hydrolase fold
HAEALIFD_00789 1.2e-55 EGP Major facilitator Superfamily
HAEALIFD_00790 7.8e-299 S ATPases associated with a variety of cellular activities
HAEALIFD_00791 3.7e-179 glkA 2.7.1.2 G ROK family
HAEALIFD_00792 3.2e-12 EGP Major facilitator superfamily
HAEALIFD_00793 1.3e-49 EGP Major facilitator superfamily
HAEALIFD_00794 2.3e-34 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
HAEALIFD_00795 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
HAEALIFD_00796 3.4e-216 MA20_36090 S Psort location Cytoplasmic, score 8.87
HAEALIFD_00797 2.1e-24 L Transposase
HAEALIFD_00799 3.1e-148 S Sulfite exporter TauE/SafE
HAEALIFD_00800 1.1e-140 V FtsX-like permease family
HAEALIFD_00802 4.2e-164 EG EamA-like transporter family
HAEALIFD_00803 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HAEALIFD_00804 1.4e-140 3.5.2.6 V Beta-lactamase enzyme family
HAEALIFD_00805 2.7e-168 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
HAEALIFD_00806 3.2e-103
HAEALIFD_00807 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
HAEALIFD_00808 1.2e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HAEALIFD_00809 2.6e-163 glcU G Sugar transport protein
HAEALIFD_00810 6.2e-196 K helix_turn_helix, arabinose operon control protein
HAEALIFD_00812 3.9e-36 rpmE J Binds the 23S rRNA
HAEALIFD_00813 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAEALIFD_00814 6.7e-184 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HAEALIFD_00815 1.1e-48 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HAEALIFD_00816 2e-115 ywlC 2.7.7.87 J Belongs to the SUA5 family
HAEALIFD_00817 2.3e-191 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HAEALIFD_00818 1.2e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HAEALIFD_00819 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HAEALIFD_00820 3.1e-127 KT Transcriptional regulatory protein, C terminal
HAEALIFD_00821 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HAEALIFD_00822 6.9e-161 supH S Sucrose-6F-phosphate phosphohydrolase
HAEALIFD_00823 6.5e-273 recD2 3.6.4.12 L PIF1-like helicase
HAEALIFD_00825 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HAEALIFD_00826 2.4e-170
HAEALIFD_00827 1.8e-119 L Single-strand binding protein family
HAEALIFD_00828 0.0 pepO 3.4.24.71 O Peptidase family M13
HAEALIFD_00829 3.1e-127 S Short repeat of unknown function (DUF308)
HAEALIFD_00830 3.2e-149 map 3.4.11.18 E Methionine aminopeptidase
HAEALIFD_00831 3.2e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HAEALIFD_00832 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HAEALIFD_00833 8.4e-198 yghZ C Aldo/keto reductase family
HAEALIFD_00834 1.7e-79 EGP Major Facilitator Superfamily
HAEALIFD_00835 3.6e-93 K acetyltransferase
HAEALIFD_00836 0.0 ctpE P E1-E2 ATPase
HAEALIFD_00837 0.0 macB_2 V ATPases associated with a variety of cellular activities
HAEALIFD_00838 1.8e-226 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HAEALIFD_00839 4.7e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
HAEALIFD_00840 5.7e-233 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HAEALIFD_00841 2.2e-243 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
HAEALIFD_00842 3.5e-126 XK27_08050 O prohibitin homologues
HAEALIFD_00843 2.1e-274 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
HAEALIFD_00844 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HAEALIFD_00845 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAEALIFD_00846 2.5e-309 L DEAD-like helicases superfamily
HAEALIFD_00847 1.9e-102 cas5d S CRISPR-associated protein (Cas_Cas5)
HAEALIFD_00848 2.5e-245 csd1 S CRISPR-associated protein (Cas_Csd1)
HAEALIFD_00849 1.3e-149 cas7c L CRISPR-associated protein Cas7
HAEALIFD_00850 2e-110 cas4 3.1.12.1 L Domain of unknown function DUF83
HAEALIFD_00851 1.3e-177 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAEALIFD_00852 3.2e-41 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HAEALIFD_00854 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
HAEALIFD_00855 8.5e-20 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HAEALIFD_00856 5.5e-189 K Periplasmic binding protein domain
HAEALIFD_00857 2.6e-126 G ABC transporter permease
HAEALIFD_00858 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HAEALIFD_00859 1.1e-62 G carbohydrate transport
HAEALIFD_00860 2e-277 G Bacterial extracellular solute-binding protein
HAEALIFD_00861 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAEALIFD_00862 4.6e-310 E ABC transporter, substrate-binding protein, family 5
HAEALIFD_00863 7.9e-169 P Binding-protein-dependent transport system inner membrane component
HAEALIFD_00864 1.1e-162 EP Binding-protein-dependent transport system inner membrane component
HAEALIFD_00865 5.2e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
HAEALIFD_00866 7.5e-155 sapF E ATPases associated with a variety of cellular activities
HAEALIFD_00867 3.7e-190 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAEALIFD_00868 2.8e-307 3.6.4.12 K Putative DNA-binding domain
HAEALIFD_00869 3e-165 tnp7109-21 L Integrase core domain
HAEALIFD_00870 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
HAEALIFD_00871 9e-40
HAEALIFD_00872 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
HAEALIFD_00874 1.4e-46 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HAEALIFD_00876 2.8e-241 pbuX F Permease family
HAEALIFD_00877 3e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HAEALIFD_00878 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
HAEALIFD_00879 0.0 pcrA 3.6.4.12 L DNA helicase
HAEALIFD_00880 8.2e-64 S Domain of unknown function (DUF4418)
HAEALIFD_00881 1.9e-212 V FtsX-like permease family
HAEALIFD_00882 1.3e-127 lolD V ABC transporter
HAEALIFD_00883 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAEALIFD_00884 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
HAEALIFD_00885 1.9e-135 pgm3 G Phosphoglycerate mutase family
HAEALIFD_00886 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HAEALIFD_00887 1.1e-36
HAEALIFD_00888 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAEALIFD_00889 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAEALIFD_00890 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAEALIFD_00891 1.3e-47 3.4.23.43 S Type IV leader peptidase family
HAEALIFD_00892 6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAEALIFD_00893 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAEALIFD_00894 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HAEALIFD_00895 3.4e-15
HAEALIFD_00896 1.7e-120 K helix_turn_helix, Lux Regulon
HAEALIFD_00897 5.2e-08 3.4.22.70 M Sortase family
HAEALIFD_00898 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HAEALIFD_00899 3.6e-290 sufB O FeS assembly protein SufB
HAEALIFD_00900 2.6e-233 sufD O FeS assembly protein SufD
HAEALIFD_00901 1.4e-144 sufC O FeS assembly ATPase SufC
HAEALIFD_00902 7.7e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAEALIFD_00903 8.8e-101 iscU C SUF system FeS assembly protein, NifU family
HAEALIFD_00904 1.2e-108 yitW S Iron-sulfur cluster assembly protein
HAEALIFD_00905 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HAEALIFD_00906 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
HAEALIFD_00908 1.4e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HAEALIFD_00909 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HAEALIFD_00910 2e-197 phoH T PhoH-like protein
HAEALIFD_00911 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HAEALIFD_00912 2.4e-251 corC S CBS domain
HAEALIFD_00913 5.1e-187 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAEALIFD_00914 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HAEALIFD_00915 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HAEALIFD_00916 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HAEALIFD_00917 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HAEALIFD_00918 4.8e-190 S alpha beta
HAEALIFD_00919 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HAEALIFD_00920 1.8e-225 ilvE 2.6.1.42 E Amino-transferase class IV
HAEALIFD_00921 2.9e-46 S phosphoesterase or phosphohydrolase
HAEALIFD_00922 2.8e-119 3.1.4.37 T RNA ligase
HAEALIFD_00923 1.2e-135 S UPF0126 domain
HAEALIFD_00924 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
HAEALIFD_00925 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HAEALIFD_00926 1.6e-244 hemN H Involved in the biosynthesis of porphyrin-containing compound
HAEALIFD_00927 4e-13 S Membrane
HAEALIFD_00928 5.9e-291 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HAEALIFD_00929 0.0 tetP J Elongation factor G, domain IV
HAEALIFD_00930 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HAEALIFD_00931 5e-303 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HAEALIFD_00932 3.6e-82
HAEALIFD_00933 1.1e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
HAEALIFD_00934 8e-182 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
HAEALIFD_00935 4.5e-158 ybeM S Carbon-nitrogen hydrolase
HAEALIFD_00936 1.9e-49 S Sel1-like repeats.
HAEALIFD_00937 2.9e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HAEALIFD_00938 2.4e-35 L Helix-turn-helix domain
HAEALIFD_00939 1.2e-140 L Transposase
HAEALIFD_00940 1.6e-28
HAEALIFD_00941 2.3e-31 XK26_04895
HAEALIFD_00942 5.1e-22 XK26_04895
HAEALIFD_00943 0.0 KL Type III restriction enzyme res subunit
HAEALIFD_00944 9.5e-38 L Eco57I restriction-modification methylase
HAEALIFD_00945 1.8e-55 L Eco57I restriction-modification methylase
HAEALIFD_00946 2.8e-182 3.1.21.4 V Type III restriction enzyme res subunit
HAEALIFD_00947 2.5e-56 S SIR2-like domain
HAEALIFD_00948 2.3e-227 S AAA-like domain
HAEALIFD_00949 0.0 S Protein of unknown function DUF262
HAEALIFD_00950 2.8e-28
HAEALIFD_00951 6.1e-25 rarD 3.4.17.13 E Rard protein
HAEALIFD_00952 4.7e-137 L IstB-like ATP binding protein
HAEALIFD_00953 1.3e-245 L Transposase
HAEALIFD_00954 1.4e-64 rarD 3.4.17.13 E Rard protein
HAEALIFD_00955 3e-178 I alpha/beta hydrolase fold
HAEALIFD_00956 2.2e-207 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HAEALIFD_00957 3.4e-100 sixA T Phosphoglycerate mutase family
HAEALIFD_00958 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HAEALIFD_00959 9.6e-163 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
HAEALIFD_00961 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HAEALIFD_00962 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HAEALIFD_00963 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HAEALIFD_00964 6.1e-279 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HAEALIFD_00965 3.4e-180 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
HAEALIFD_00966 1.9e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HAEALIFD_00967 8.2e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HAEALIFD_00968 3.2e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAEALIFD_00969 1e-16 K MerR family regulatory protein
HAEALIFD_00970 4.7e-196 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HAEALIFD_00971 7.4e-142
HAEALIFD_00972 1.3e-16 K Psort location Cytoplasmic, score
HAEALIFD_00973 9.1e-16 KLT Protein tyrosine kinase
HAEALIFD_00974 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HAEALIFD_00975 4.4e-242 vbsD V MatE
HAEALIFD_00976 7.3e-132 S Enoyl-(Acyl carrier protein) reductase
HAEALIFD_00977 2.3e-133 magIII L endonuclease III
HAEALIFD_00978 1.7e-93 laaE K Transcriptional regulator PadR-like family
HAEALIFD_00979 1.8e-176 S Membrane transport protein
HAEALIFD_00980 1.1e-67 4.1.1.44 S Cupin domain
HAEALIFD_00981 7e-225 hipA 2.7.11.1 S HipA N-terminal domain
HAEALIFD_00982 1.4e-40 K Helix-turn-helix
HAEALIFD_00983 3.1e-49 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
HAEALIFD_00984 1.6e-18
HAEALIFD_00985 9.3e-101 K Bacterial regulatory proteins, tetR family
HAEALIFD_00986 2e-91 T Domain of unknown function (DUF4234)
HAEALIFD_00987 2.1e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
HAEALIFD_00988 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HAEALIFD_00989 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAEALIFD_00990 4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
HAEALIFD_00991 1.3e-90 dkgB S Oxidoreductase, aldo keto reductase family protein
HAEALIFD_00993 5.1e-289 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HAEALIFD_00994 0.0 pafB K WYL domain
HAEALIFD_00995 1e-51
HAEALIFD_00996 0.0 helY L DEAD DEAH box helicase
HAEALIFD_00997 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HAEALIFD_00998 3.6e-142 pgp 3.1.3.18 S HAD-hyrolase-like
HAEALIFD_01000 3.6e-90 K Putative zinc ribbon domain
HAEALIFD_01001 7.2e-126 S GyrI-like small molecule binding domain
HAEALIFD_01002 3.3e-24 L DNA integration
HAEALIFD_01003 5.5e-15
HAEALIFD_01004 7.3e-62
HAEALIFD_01005 8e-120 K helix_turn_helix, mercury resistance
HAEALIFD_01006 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
HAEALIFD_01007 1.2e-141 S Bacterial protein of unknown function (DUF881)
HAEALIFD_01008 2.6e-31 sbp S Protein of unknown function (DUF1290)
HAEALIFD_01009 1.8e-173 S Bacterial protein of unknown function (DUF881)
HAEALIFD_01010 1.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAEALIFD_01011 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
HAEALIFD_01012 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HAEALIFD_01013 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
HAEALIFD_01014 2.3e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAEALIFD_01015 5.4e-161 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HAEALIFD_01016 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HAEALIFD_01017 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
HAEALIFD_01018 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HAEALIFD_01019 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HAEALIFD_01020 5.7e-30
HAEALIFD_01021 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HAEALIFD_01022 5e-246
HAEALIFD_01023 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HAEALIFD_01024 1.9e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HAEALIFD_01025 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HAEALIFD_01026 2.6e-44 yajC U Preprotein translocase subunit
HAEALIFD_01027 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HAEALIFD_01028 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HAEALIFD_01029 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HAEALIFD_01030 1e-131 yebC K transcriptional regulatory protein
HAEALIFD_01031 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
HAEALIFD_01032 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAEALIFD_01033 2.2e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAEALIFD_01036 2.6e-262
HAEALIFD_01040 2.8e-156 S PAC2 family
HAEALIFD_01041 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HAEALIFD_01042 7.1e-160 G Fructosamine kinase
HAEALIFD_01043 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HAEALIFD_01044 2.3e-221 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HAEALIFD_01045 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
HAEALIFD_01046 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HAEALIFD_01047 1.1e-142 yoaK S Protein of unknown function (DUF1275)
HAEALIFD_01048 7.5e-253 brnQ U Component of the transport system for branched-chain amino acids
HAEALIFD_01051 1.2e-242 mepA_6 V MatE
HAEALIFD_01052 8e-162 S Sucrose-6F-phosphate phosphohydrolase
HAEALIFD_01053 1.3e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HAEALIFD_01054 8e-33 secG U Preprotein translocase SecG subunit
HAEALIFD_01055 6.9e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HAEALIFD_01056 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
HAEALIFD_01057 9e-173 whiA K May be required for sporulation
HAEALIFD_01058 1.5e-177 rapZ S Displays ATPase and GTPase activities
HAEALIFD_01059 7.5e-180 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
HAEALIFD_01060 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HAEALIFD_01061 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAEALIFD_01062 2.1e-77
HAEALIFD_01063 3.1e-58 V MacB-like periplasmic core domain
HAEALIFD_01064 3.2e-50 K Transcriptional regulatory protein, C terminal
HAEALIFD_01065 3.9e-37 K Transcriptional regulatory protein, C terminal
HAEALIFD_01066 4.3e-232 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HAEALIFD_01067 4.5e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HAEALIFD_01068 2.6e-302 ybiT S ABC transporter
HAEALIFD_01069 1.4e-197 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HAEALIFD_01070 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HAEALIFD_01071 4.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
HAEALIFD_01072 6.4e-218 GK ROK family
HAEALIFD_01073 1.5e-177 2.7.1.2 GK ROK family
HAEALIFD_01074 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
HAEALIFD_01075 1e-168 G ABC transporter permease
HAEALIFD_01076 1.4e-173 G Binding-protein-dependent transport system inner membrane component
HAEALIFD_01077 5e-243 G Bacterial extracellular solute-binding protein
HAEALIFD_01078 7.1e-308 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HAEALIFD_01079 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HAEALIFD_01080 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HAEALIFD_01081 3.5e-227 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HAEALIFD_01082 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
HAEALIFD_01083 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HAEALIFD_01084 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HAEALIFD_01085 4e-127 3.2.1.8 S alpha beta
HAEALIFD_01086 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAEALIFD_01087 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HAEALIFD_01088 5.8e-88 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAEALIFD_01089 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
HAEALIFD_01090 5.7e-91
HAEALIFD_01091 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
HAEALIFD_01092 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HAEALIFD_01093 1.9e-273 G ABC transporter substrate-binding protein
HAEALIFD_01094 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
HAEALIFD_01095 5.5e-131 M Peptidase family M23
HAEALIFD_01097 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAEALIFD_01098 3.2e-101 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
HAEALIFD_01099 3e-159 yeaZ 2.3.1.234 O Glycoprotease family
HAEALIFD_01100 1.7e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
HAEALIFD_01101 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
HAEALIFD_01102 0.0 comE S Competence protein
HAEALIFD_01103 3.1e-84 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
HAEALIFD_01104 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAEALIFD_01105 4.9e-168 ET Bacterial periplasmic substrate-binding proteins
HAEALIFD_01106 3.7e-171 corA P CorA-like Mg2+ transporter protein
HAEALIFD_01107 4e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HAEALIFD_01108 6.5e-298 E Serine carboxypeptidase
HAEALIFD_01109 0.0 S Psort location Cytoplasmic, score 8.87
HAEALIFD_01110 2.1e-111 S Domain of unknown function (DUF4194)
HAEALIFD_01111 5.7e-283 S Psort location Cytoplasmic, score 8.87
HAEALIFD_01112 1.8e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HAEALIFD_01113 7.6e-64 yeaO K Protein of unknown function, DUF488
HAEALIFD_01114 1.2e-120 ydaF_1 J Acetyltransferase (GNAT) domain
HAEALIFD_01115 1.2e-97 MA20_25245 K FR47-like protein
HAEALIFD_01116 6.2e-55 K Transcriptional regulator
HAEALIFD_01117 6.9e-37 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
HAEALIFD_01119 1.4e-33 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HAEALIFD_01121 1.2e-185 S Acetyltransferase (GNAT) domain
HAEALIFD_01122 1.6e-76 qseC 2.7.13.3 T Histidine kinase
HAEALIFD_01123 2.9e-133 S SOS response associated peptidase (SRAP)
HAEALIFD_01124 1.3e-125
HAEALIFD_01125 2.5e-80 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAEALIFD_01126 9.2e-162 rpoC M heme binding
HAEALIFD_01127 3e-28 EGP Major facilitator Superfamily
HAEALIFD_01128 9.8e-100 EGP Major facilitator Superfamily
HAEALIFD_01130 5.4e-156
HAEALIFD_01131 3.1e-11 CE Amino acid permease
HAEALIFD_01132 3.9e-106 ypjC S Putative ABC-transporter type IV
HAEALIFD_01133 7.4e-109 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
HAEALIFD_01134 2.4e-192 V VanZ like family
HAEALIFD_01135 3.5e-146 KT RESPONSE REGULATOR receiver
HAEALIFD_01136 2.7e-70 pdxH S Pfam:Pyridox_oxidase
HAEALIFD_01137 3.8e-141 yijF S Domain of unknown function (DUF1287)
HAEALIFD_01138 5e-133 C Putative TM nitroreductase
HAEALIFD_01139 1.2e-108
HAEALIFD_01141 3.2e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
HAEALIFD_01142 1.3e-78 S Bacterial PH domain
HAEALIFD_01143 5.4e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HAEALIFD_01144 2.4e-69 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HAEALIFD_01145 4.6e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAEALIFD_01147 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAEALIFD_01148 8.1e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAEALIFD_01149 2.6e-92
HAEALIFD_01150 4.5e-236 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAEALIFD_01151 5.1e-284 thrC 4.2.3.1 E Threonine synthase N terminus
HAEALIFD_01152 8.1e-123 S ABC-2 family transporter protein
HAEALIFD_01153 5.1e-120 S ABC-2 family transporter protein
HAEALIFD_01154 4.2e-175 V ATPases associated with a variety of cellular activities
HAEALIFD_01155 2.7e-56 K helix_turn_helix gluconate operon transcriptional repressor
HAEALIFD_01156 7.5e-123 S Haloacid dehalogenase-like hydrolase
HAEALIFD_01157 6e-292 recN L May be involved in recombinational repair of damaged DNA
HAEALIFD_01158 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAEALIFD_01159 1.9e-227 trkB P Cation transport protein
HAEALIFD_01160 6.8e-116 trkA P TrkA-N domain
HAEALIFD_01161 3.6e-104
HAEALIFD_01162 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HAEALIFD_01164 2.3e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HAEALIFD_01165 3.6e-159 L Tetratricopeptide repeat
HAEALIFD_01166 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAEALIFD_01167 3.5e-143 S Putative ABC-transporter type IV
HAEALIFD_01168 6.1e-108 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HAEALIFD_01169 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
HAEALIFD_01170 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HAEALIFD_01171 5.3e-284 3.6.4.12 K Putative DNA-binding domain
HAEALIFD_01172 4.6e-105 3.1.21.3 V type I restriction modification DNA specificity domain
HAEALIFD_01173 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
HAEALIFD_01174 5e-156 S Domain of unknown function (DUF4357)
HAEALIFD_01175 2.4e-30
HAEALIFD_01176 1e-178 L Phage integrase family
HAEALIFD_01177 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HAEALIFD_01178 1.4e-84 argR K Regulates arginine biosynthesis genes
HAEALIFD_01179 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAEALIFD_01180 1.6e-246 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HAEALIFD_01181 3.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HAEALIFD_01182 4.3e-214 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HAEALIFD_01183 3.2e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HAEALIFD_01184 2.5e-86
HAEALIFD_01185 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HAEALIFD_01186 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HAEALIFD_01187 2.4e-161 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAEALIFD_01188 1.2e-135 ybbL V ATPases associated with a variety of cellular activities
HAEALIFD_01189 2.5e-136 ybbM V Uncharacterised protein family (UPF0014)
HAEALIFD_01190 3e-53 IQ oxidoreductase activity
HAEALIFD_01192 2.2e-76 K AraC-like ligand binding domain
HAEALIFD_01193 3.1e-237 rutG F Permease family
HAEALIFD_01194 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
HAEALIFD_01195 6.3e-188 MA20_14895 S Conserved hypothetical protein 698
HAEALIFD_01196 3.5e-146 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
HAEALIFD_01197 1.2e-117 3.1.3.27 E haloacid dehalogenase-like hydrolase
HAEALIFD_01198 5.2e-292 2.4.1.166 GT2 M Glycosyltransferase like family 2
HAEALIFD_01200 2.1e-221 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HAEALIFD_01201 5e-129 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HAEALIFD_01202 7.2e-126 ypfH S Phospholipase/Carboxylesterase
HAEALIFD_01203 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HAEALIFD_01204 2.5e-24
HAEALIFD_01205 2.1e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HAEALIFD_01206 2.8e-66 S Zincin-like metallopeptidase
HAEALIFD_01207 6.6e-86 S Helix-turn-helix
HAEALIFD_01208 6.7e-197 S Short C-terminal domain
HAEALIFD_01209 2.7e-22
HAEALIFD_01210 5.3e-149
HAEALIFD_01211 4.5e-79 K Psort location Cytoplasmic, score
HAEALIFD_01212 1.7e-256 KLT Protein tyrosine kinase
HAEALIFD_01213 7.9e-66 S Cupin 2, conserved barrel domain protein
HAEALIFD_01214 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
HAEALIFD_01215 5.6e-59 yccF S Inner membrane component domain
HAEALIFD_01216 8.6e-120 E Psort location Cytoplasmic, score 8.87
HAEALIFD_01217 4.9e-34 L Psort location Cytoplasmic, score 8.87
HAEALIFD_01218 6e-58 S pathogenesis
HAEALIFD_01219 3.6e-69
HAEALIFD_01222 5.7e-88 topB 5.99.1.2 L DNA topoisomerase
HAEALIFD_01223 2.9e-87 topB 5.99.1.2 L DNA topoisomerase
HAEALIFD_01226 1.1e-84 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HAEALIFD_01227 1.3e-57 2.7.1.2 GK ROK family
HAEALIFD_01228 4.7e-109 M1-530 S Protein of unknown function (DUF4127)
HAEALIFD_01229 7.1e-94 lacG G Binding-protein-dependent transport system inner membrane component
HAEALIFD_01230 7.7e-144 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HAEALIFD_01231 1.5e-305 EGP Major facilitator Superfamily
HAEALIFD_01232 2.5e-226 mntH P H( )-stimulated, divalent metal cation uptake system
HAEALIFD_01233 1.7e-122 L Protein of unknown function (DUF1524)
HAEALIFD_01234 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
HAEALIFD_01235 9.3e-11 3.2.1.14 GH18 EM Domain of unknown function (DUF5011)
HAEALIFD_01236 3.2e-201 K helix_turn _helix lactose operon repressor
HAEALIFD_01237 3.1e-242 G Glycosyl hydrolases family 43
HAEALIFD_01240 8.1e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HAEALIFD_01241 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HAEALIFD_01242 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HAEALIFD_01243 5.8e-208 K helix_turn _helix lactose operon repressor
HAEALIFD_01244 8.9e-130 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAEALIFD_01245 3.2e-155 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HAEALIFD_01246 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HAEALIFD_01247 4.3e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HAEALIFD_01248 3.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HAEALIFD_01249 2.7e-293 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
HAEALIFD_01250 8.8e-213 gatC G PTS system sugar-specific permease component
HAEALIFD_01251 1.2e-172 K Putative sugar-binding domain
HAEALIFD_01253 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
HAEALIFD_01254 3.5e-277 abcT3 P ATPases associated with a variety of cellular activities
HAEALIFD_01255 6.9e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
HAEALIFD_01256 2.6e-34 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
HAEALIFD_01257 1.8e-31 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
HAEALIFD_01258 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
HAEALIFD_01259 3e-120 mgtC S MgtC family
HAEALIFD_01261 6.9e-201
HAEALIFD_01263 1.2e-189
HAEALIFD_01264 0.0 pgi 5.3.1.9 G Belongs to the GPI family
HAEALIFD_01267 1.3e-174 S Auxin Efflux Carrier
HAEALIFD_01268 1.1e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HAEALIFD_01269 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HAEALIFD_01270 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAEALIFD_01272 7.6e-92 ilvN 2.2.1.6 E ACT domain
HAEALIFD_01273 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HAEALIFD_01274 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HAEALIFD_01275 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HAEALIFD_01276 1e-113 yceD S Uncharacterized ACR, COG1399
HAEALIFD_01277 4.7e-107
HAEALIFD_01278 2.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAEALIFD_01279 2e-58 S Protein of unknown function (DUF3039)
HAEALIFD_01280 0.0 yjjK S ABC transporter
HAEALIFD_01281 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
HAEALIFD_01282 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAEALIFD_01283 1.4e-164 P Cation efflux family
HAEALIFD_01284 8.4e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAEALIFD_01285 9.4e-217 S Endonuclease/Exonuclease/phosphatase family
HAEALIFD_01286 1.3e-93 argO S LysE type translocator
HAEALIFD_01287 8.5e-295 ydfD EK Alanine-glyoxylate amino-transferase
HAEALIFD_01288 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HAEALIFD_01289 1.8e-34 CP_0960 S Belongs to the UPF0109 family
HAEALIFD_01290 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAEALIFD_01291 7.1e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HAEALIFD_01292 3.4e-82 hsp20 O Hsp20/alpha crystallin family
HAEALIFD_01293 1.7e-105 XK27_02070 S Nitroreductase family
HAEALIFD_01294 4.7e-123 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HAEALIFD_01295 8.4e-248 U Sodium:dicarboxylate symporter family
HAEALIFD_01296 1.4e-302
HAEALIFD_01299 7.5e-215 steT E amino acid
HAEALIFD_01300 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
HAEALIFD_01301 1.4e-29 rpmB J Ribosomal L28 family
HAEALIFD_01302 4.2e-200 yegV G pfkB family carbohydrate kinase
HAEALIFD_01304 2.3e-243 yxiO S Vacuole effluxer Atg22 like
HAEALIFD_01305 5.5e-130 K helix_turn_helix, mercury resistance
HAEALIFD_01306 2.2e-60 T Toxic component of a toxin-antitoxin (TA) module
HAEALIFD_01307 8.1e-54 relB L RelB antitoxin
HAEALIFD_01308 3.4e-35 3.4.11.5 I carboxylic ester hydrolase activity
HAEALIFD_01309 1.1e-236 K Helix-turn-helix XRE-family like proteins
HAEALIFD_01310 1e-144 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
HAEALIFD_01315 3.5e-07 S Scramblase
HAEALIFD_01316 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HAEALIFD_01317 2.8e-24 K Transcriptional regulator
HAEALIFD_01319 3.1e-34 M Belongs to the glycosyl hydrolase 28 family
HAEALIFD_01320 1.1e-57
HAEALIFD_01321 1.6e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HAEALIFD_01322 1.7e-240 MA20_36090 S Psort location Cytoplasmic, score 8.87
HAEALIFD_01323 1.7e-119 K Bacterial regulatory proteins, tetR family
HAEALIFD_01324 2.7e-132 M Mechanosensitive ion channel
HAEALIFD_01325 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HAEALIFD_01326 1.1e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HAEALIFD_01327 1.8e-62 S Domain of unknown function (DUF4854)
HAEALIFD_01328 5.2e-215 3.4.22.70 M Sortase family
HAEALIFD_01329 9.9e-286 M LPXTG cell wall anchor motif
HAEALIFD_01330 0.0 inlJ M domain protein
HAEALIFD_01331 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
HAEALIFD_01332 2.2e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAEALIFD_01333 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAEALIFD_01334 3.9e-129 M Protein of unknown function (DUF3152)
HAEALIFD_01335 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HAEALIFD_01338 3.8e-62 E Domain of unknown function (DUF5011)
HAEALIFD_01339 6.6e-70 rplI J Binds to the 23S rRNA
HAEALIFD_01340 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAEALIFD_01341 1.1e-79 ssb1 L Single-stranded DNA-binding protein
HAEALIFD_01342 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HAEALIFD_01343 1e-168 T Pfam Adenylate and Guanylate cyclase catalytic domain
HAEALIFD_01344 3.1e-58
HAEALIFD_01345 1.3e-37
HAEALIFD_01346 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAEALIFD_01347 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAEALIFD_01348 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
HAEALIFD_01349 7.5e-202 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HAEALIFD_01350 3.4e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HAEALIFD_01351 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HAEALIFD_01352 1.4e-172 plsC2 2.3.1.51 I Phosphate acyltransferases
HAEALIFD_01353 2.1e-117 nusG K Participates in transcription elongation, termination and antitermination
HAEALIFD_01354 1.2e-30 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HAEALIFD_01356 1.4e-228 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HAEALIFD_01357 1.5e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAEALIFD_01358 1.1e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAEALIFD_01359 1.8e-214 K Psort location Cytoplasmic, score
HAEALIFD_01360 3.1e-40 rpmA J Ribosomal L27 protein
HAEALIFD_01361 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HAEALIFD_01362 0.0 rne 3.1.26.12 J Ribonuclease E/G family
HAEALIFD_01363 6.5e-11 S Domain of unknown function (DUF4190)
HAEALIFD_01364 1.7e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
HAEALIFD_01365 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
HAEALIFD_01366 1.4e-254 V Efflux ABC transporter, permease protein
HAEALIFD_01367 4.9e-165 V ATPases associated with a variety of cellular activities
HAEALIFD_01368 1.4e-57
HAEALIFD_01369 5.8e-67
HAEALIFD_01370 9.5e-280 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HAEALIFD_01371 3.5e-188 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HAEALIFD_01372 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
HAEALIFD_01373 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
HAEALIFD_01374 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HAEALIFD_01375 1.8e-303 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HAEALIFD_01376 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HAEALIFD_01377 1.3e-196 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HAEALIFD_01378 2e-18 psp1 3.5.99.10 J Endoribonuclease L-PSP
HAEALIFD_01379 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
HAEALIFD_01380 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
HAEALIFD_01382 1e-153 IQ KR domain
HAEALIFD_01383 6.8e-29 4.2.1.68 M Enolase C-terminal domain-like
HAEALIFD_01384 3.6e-19 4.2.1.68 M Enolase C-terminal domain-like
HAEALIFD_01385 2.9e-16 4.2.1.68 M carboxylic acid catabolic process
HAEALIFD_01386 1.4e-184 K Bacterial regulatory proteins, lacI family
HAEALIFD_01388 2.8e-119 cyaA 4.6.1.1 S CYTH
HAEALIFD_01389 3.8e-163 trxA2 O Tetratricopeptide repeat
HAEALIFD_01390 7.9e-180
HAEALIFD_01391 2.5e-184
HAEALIFD_01392 2e-167 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HAEALIFD_01393 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HAEALIFD_01394 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAEALIFD_01395 4.7e-126
HAEALIFD_01396 7.3e-132 K Bacterial regulatory proteins, tetR family
HAEALIFD_01397 2.4e-224 G Transmembrane secretion effector
HAEALIFD_01398 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAEALIFD_01399 2.3e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
HAEALIFD_01400 7e-190 S CAAX protease self-immunity
HAEALIFD_01402 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
HAEALIFD_01403 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAEALIFD_01404 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAEALIFD_01405 8.2e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HAEALIFD_01406 2.9e-251 S Calcineurin-like phosphoesterase
HAEALIFD_01409 2.5e-99 S Domain of unknown function (DUF4143)
HAEALIFD_01410 2.4e-297 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAEALIFD_01412 3.1e-124 S HAD hydrolase, family IA, variant 3
HAEALIFD_01413 3.3e-200 P NMT1/THI5 like
HAEALIFD_01414 5.8e-138 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HAEALIFD_01415 1.1e-140
HAEALIFD_01416 1.1e-126 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HAEALIFD_01417 5.6e-256 EGP Major facilitator Superfamily
HAEALIFD_01418 6.8e-98 S GtrA-like protein
HAEALIFD_01419 1.3e-62 S Macrophage migration inhibitory factor (MIF)
HAEALIFD_01420 1.3e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HAEALIFD_01421 0.0 pepD E Peptidase family C69
HAEALIFD_01422 1.3e-107 S Phosphatidylethanolamine-binding protein
HAEALIFD_01423 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
HAEALIFD_01424 0.0 lmrA2 V ABC transporter transmembrane region
HAEALIFD_01425 0.0 lmrA1 V ABC transporter, ATP-binding protein
HAEALIFD_01426 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
HAEALIFD_01427 2.2e-190 1.1.1.65 C Aldo/keto reductase family
HAEALIFD_01428 1.5e-36 M F5/8 type C domain
HAEALIFD_01429 4.3e-55
HAEALIFD_01431 4.4e-259 L Phage integrase, N-terminal SAM-like domain
HAEALIFD_01434 1.4e-104
HAEALIFD_01435 0.0 ltrBE1 U Relaxase/Mobilisation nuclease domain
HAEALIFD_01436 1.4e-59 S Bacterial mobilisation protein (MobC)
HAEALIFD_01437 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HAEALIFD_01438 2e-180 V Abi-like protein
HAEALIFD_01439 6.5e-229 3.1.21.3 V Type I restriction modification DNA specificity domain
HAEALIFD_01441 1.8e-295 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
HAEALIFD_01442 5.6e-272
HAEALIFD_01443 1.4e-13
HAEALIFD_01444 9.4e-110 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
HAEALIFD_01445 5e-116 K WHG domain
HAEALIFD_01446 5.8e-35 L Psort location Cytoplasmic, score 8.87
HAEALIFD_01447 1.9e-121 L Integrase core domain
HAEALIFD_01448 3.5e-41 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
HAEALIFD_01449 5e-266 EGP Major Facilitator Superfamily
HAEALIFD_01450 1.2e-132
HAEALIFD_01451 2.9e-243 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HAEALIFD_01452 5.5e-55 L HNH endonuclease
HAEALIFD_01453 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HAEALIFD_01454 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HAEALIFD_01455 6.2e-105 L Transposase
HAEALIFD_01456 4.2e-42 XAC3035 O Glutaredoxin
HAEALIFD_01457 5.7e-159 S Virulence factor BrkB
HAEALIFD_01458 7.6e-100 bcp 1.11.1.15 O Redoxin
HAEALIFD_01459 1.2e-39 E ABC transporter
HAEALIFD_01460 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HAEALIFD_01461 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAEALIFD_01462 0.0 V FtsX-like permease family
HAEALIFD_01463 2.6e-129 V ABC transporter
HAEALIFD_01464 2.4e-101 K Transcriptional regulator C-terminal region
HAEALIFD_01465 1.5e-275 aroP E aromatic amino acid transport protein AroP K03293
HAEALIFD_01466 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HAEALIFD_01467 4.8e-182 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
HAEALIFD_01468 5.3e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAEALIFD_01469 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAEALIFD_01470 6.1e-252 yhjE EGP Sugar (and other) transporter
HAEALIFD_01471 3.6e-294 scrT G Transporter major facilitator family protein
HAEALIFD_01472 5.5e-74 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HAEALIFD_01473 2.1e-188 K helix_turn _helix lactose operon repressor
HAEALIFD_01474 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAEALIFD_01475 6.3e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAEALIFD_01476 2.2e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAEALIFD_01477 1e-198 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HAEALIFD_01478 1.5e-247 3.5.1.104 G Polysaccharide deacetylase
HAEALIFD_01479 4.9e-57 K Cro/C1-type HTH DNA-binding domain
HAEALIFD_01480 2e-12 E IrrE N-terminal-like domain
HAEALIFD_01481 3.9e-50 E IrrE N-terminal-like domain
HAEALIFD_01482 4.4e-64
HAEALIFD_01483 1.3e-60
HAEALIFD_01484 6.7e-27 K Psort location Cytoplasmic, score 8.87
HAEALIFD_01485 1.9e-89 XK26_06155 K Psort location Cytoplasmic, score
HAEALIFD_01486 0.0 tetP J elongation factor G
HAEALIFD_01487 4.4e-109
HAEALIFD_01488 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HAEALIFD_01489 5.4e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HAEALIFD_01490 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HAEALIFD_01491 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HAEALIFD_01492 1.4e-10 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HAEALIFD_01493 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAEALIFD_01494 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
HAEALIFD_01495 2.6e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAEALIFD_01496 1.5e-247 dgt 3.1.5.1 F Phosphohydrolase-associated domain
HAEALIFD_01497 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HAEALIFD_01498 3.9e-159 K Helix-turn-helix domain, rpiR family
HAEALIFD_01499 7.9e-227 K Putative ATP-dependent DNA helicase recG C-terminal
HAEALIFD_01500 1.4e-44 S Memo-like protein
HAEALIFD_01502 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAEALIFD_01503 4.5e-180 adh3 C Zinc-binding dehydrogenase
HAEALIFD_01504 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HAEALIFD_01505 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HAEALIFD_01506 4.3e-73 zur P Belongs to the Fur family
HAEALIFD_01507 9.8e-45
HAEALIFD_01508 2.2e-153 S TIGRFAM TIGR03943 family protein
HAEALIFD_01509 1.1e-201 ycgR S Predicted permease
HAEALIFD_01510 2.3e-23 J Ribosomal L32p protein family
HAEALIFD_01511 8.2e-15 rpmJ J Ribosomal protein L36
HAEALIFD_01512 2e-42 rpmE2 J Ribosomal protein L31
HAEALIFD_01513 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAEALIFD_01514 6.1e-48 rpmB J Ribosomal L28 family
HAEALIFD_01515 1.8e-139 S cobalamin synthesis protein
HAEALIFD_01516 2.7e-163 P Zinc-uptake complex component A periplasmic
HAEALIFD_01518 0.0 lysX S Uncharacterised conserved protein (DUF2156)
HAEALIFD_01519 4.6e-247 S Putative esterase
HAEALIFD_01520 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HAEALIFD_01521 1.9e-239 purD 6.3.4.13 F Belongs to the GARS family
HAEALIFD_01522 2e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HAEALIFD_01523 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HAEALIFD_01524 3e-303 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
HAEALIFD_01525 2e-32
HAEALIFD_01526 4.7e-69 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAEALIFD_01527 8.9e-33 K DNA-binding transcription factor activity
HAEALIFD_01528 4.3e-152 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
HAEALIFD_01529 2.1e-93 S Protein of unknown function (DUF4230)
HAEALIFD_01530 3.3e-110
HAEALIFD_01531 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HAEALIFD_01532 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HAEALIFD_01533 3.7e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HAEALIFD_01534 0.0 M Parallel beta-helix repeats
HAEALIFD_01535 1.2e-227 M Glycosyl transferase 4-like domain
HAEALIFD_01536 5.9e-199 ltaE 4.1.2.48 E Beta-eliminating lyase
HAEALIFD_01538 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAEALIFD_01539 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HAEALIFD_01540 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAEALIFD_01541 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAEALIFD_01542 0.0 S Esterase-like activity of phytase
HAEALIFD_01543 2.7e-192 EGP Transmembrane secretion effector
HAEALIFD_01545 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAEALIFD_01546 6.6e-82 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAEALIFD_01547 1e-237 carA 6.3.5.5 F Belongs to the CarA family
HAEALIFD_01548 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HAEALIFD_01549 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HAEALIFD_01550 0.0 S Protein of unknown function DUF262
HAEALIFD_01551 1.1e-116 K helix_turn_helix, Lux Regulon
HAEALIFD_01552 3.2e-267 T Histidine kinase
HAEALIFD_01553 1e-97 S Domain of unknown function (DUF5067)
HAEALIFD_01554 6.6e-132 ybhL S Belongs to the BI1 family
HAEALIFD_01555 7.8e-169 ydeD EG EamA-like transporter family
HAEALIFD_01556 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HAEALIFD_01557 1.6e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HAEALIFD_01558 4.5e-184 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAEALIFD_01559 7.7e-137 fic D Fic/DOC family
HAEALIFD_01560 0.0 ftsK D FtsK SpoIIIE family protein
HAEALIFD_01561 3.2e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAEALIFD_01562 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
HAEALIFD_01563 1.6e-80 K Helix-turn-helix XRE-family like proteins
HAEALIFD_01564 3.7e-40 S Protein of unknown function (DUF3046)
HAEALIFD_01565 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAEALIFD_01566 2.9e-87 recX S Modulates RecA activity
HAEALIFD_01567 1e-07
HAEALIFD_01569 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HAEALIFD_01570 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HAEALIFD_01571 1.1e-192 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAEALIFD_01572 4.3e-109
HAEALIFD_01573 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
HAEALIFD_01574 0.0 pknL 2.7.11.1 KLT PASTA
HAEALIFD_01575 5.2e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
HAEALIFD_01576 1.7e-122
HAEALIFD_01577 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HAEALIFD_01578 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HAEALIFD_01579 7.6e-277 aspA 4.3.1.1 E Fumarase C C-terminus
HAEALIFD_01580 1.2e-36 K Transcriptional regulator
HAEALIFD_01581 0.0 lhr L DEAD DEAH box helicase
HAEALIFD_01582 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HAEALIFD_01583 1.3e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
HAEALIFD_01584 1.4e-187 S Protein of unknown function (DUF3071)
HAEALIFD_01585 1.4e-47 S Domain of unknown function (DUF4193)
HAEALIFD_01586 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HAEALIFD_01587 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAEALIFD_01588 9e-28
HAEALIFD_01589 3.6e-233 L Phage integrase family
HAEALIFD_01590 2.1e-140 fic D Fic/DOC family
HAEALIFD_01591 1.1e-26
HAEALIFD_01592 1.6e-26 L DNA integration
HAEALIFD_01594 4.6e-73 S EcsC protein family
HAEALIFD_01595 2e-232 hsdM 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
HAEALIFD_01596 1.1e-205 S HipA-like C-terminal domain
HAEALIFD_01597 7e-34
HAEALIFD_01598 1.3e-207 E Belongs to the peptidase S1B family
HAEALIFD_01599 1.1e-39 T Toxic component of a toxin-antitoxin (TA) module
HAEALIFD_01600 1.1e-49 relB L RelB antitoxin
HAEALIFD_01601 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAEALIFD_01602 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
HAEALIFD_01603 2.1e-94 P ABC-type metal ion transport system permease component
HAEALIFD_01604 2.7e-224 S Peptidase dimerisation domain
HAEALIFD_01605 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAEALIFD_01606 2.3e-22
HAEALIFD_01607 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HAEALIFD_01608 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAEALIFD_01609 1.3e-113 S Protein of unknown function (DUF3000)
HAEALIFD_01610 2.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
HAEALIFD_01611 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HAEALIFD_01612 3.6e-255 clcA_2 P Voltage gated chloride channel
HAEALIFD_01613 1.8e-142 cobB2 K Sir2 family
HAEALIFD_01614 2.2e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HAEALIFD_01615 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HAEALIFD_01616 1.2e-145 ypfH S Phospholipase/Carboxylesterase
HAEALIFD_01617 0.0 yjcE P Sodium/hydrogen exchanger family
HAEALIFD_01618 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HAEALIFD_01619 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HAEALIFD_01620 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HAEALIFD_01622 1.9e-173 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAEALIFD_01623 2.6e-269 KLT Domain of unknown function (DUF4032)
HAEALIFD_01624 7.5e-155
HAEALIFD_01625 1.1e-178 3.4.22.70 M Sortase family
HAEALIFD_01626 3.4e-246 M LPXTG-motif cell wall anchor domain protein
HAEALIFD_01627 0.0 S LPXTG-motif cell wall anchor domain protein
HAEALIFD_01628 3.6e-102 L Helix-turn-helix domain
HAEALIFD_01629 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
HAEALIFD_01630 3.4e-174 K Psort location Cytoplasmic, score
HAEALIFD_01631 0.0 KLT Protein tyrosine kinase
HAEALIFD_01632 7.1e-150 O Thioredoxin
HAEALIFD_01634 1.6e-213 S G5
HAEALIFD_01635 6.3e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HAEALIFD_01636 1.6e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HAEALIFD_01637 4.4e-112 S LytR cell envelope-related transcriptional attenuator
HAEALIFD_01638 1.4e-278 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HAEALIFD_01639 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HAEALIFD_01640 0.0 M Conserved repeat domain
HAEALIFD_01641 0.0 murJ KLT MviN-like protein
HAEALIFD_01642 1.1e-201 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HAEALIFD_01643 8e-244 parB K Belongs to the ParB family
HAEALIFD_01644 1.2e-177 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HAEALIFD_01645 1.3e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HAEALIFD_01646 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
HAEALIFD_01647 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
HAEALIFD_01648 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HAEALIFD_01649 2.9e-298 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAEALIFD_01650 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HAEALIFD_01651 1.8e-237 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAEALIFD_01652 3.8e-86 S Protein of unknown function (DUF721)
HAEALIFD_01653 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAEALIFD_01654 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAEALIFD_01655 4.6e-73 S Transmembrane domain of unknown function (DUF3566)
HAEALIFD_01656 5.8e-07 S Parallel beta-helix repeats
HAEALIFD_01657 1e-186 G Glycosyl hydrolases family 43
HAEALIFD_01658 5.5e-188 K Periplasmic binding protein domain
HAEALIFD_01659 8.9e-228 I Serine aminopeptidase, S33
HAEALIFD_01660 1.4e-08 K helix_turn _helix lactose operon repressor
HAEALIFD_01661 9.6e-42 S Protein of unknown function (DUF2442)
HAEALIFD_01662 8.9e-119 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HAEALIFD_01663 2.5e-264 hsdBM 2.1.1.72 L Eco57I restriction-modification methylase
HAEALIFD_01664 7.9e-182 pstIR 2.1.1.72, 3.1.21.4 L BsuBI/PstI restriction endonuclease C-terminus
HAEALIFD_01665 1.3e-224
HAEALIFD_01667 9.6e-180 L Phage integrase family
HAEALIFD_01669 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HAEALIFD_01670 2e-121 gntR K FCD
HAEALIFD_01671 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HAEALIFD_01672 0.0 3.2.1.55 GH51 G arabinose metabolic process
HAEALIFD_01675 0.0 G Glycosyl hydrolase family 20, domain 2
HAEALIFD_01676 1.4e-187 K helix_turn _helix lactose operon repressor
HAEALIFD_01677 9.5e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HAEALIFD_01678 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HAEALIFD_01679 1.4e-260 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HAEALIFD_01680 5.7e-135 S Protein of unknown function DUF45
HAEALIFD_01681 1.9e-83 dps P Belongs to the Dps family
HAEALIFD_01682 3.4e-189 yddG EG EamA-like transporter family
HAEALIFD_01683 1.2e-241 ytfL P Transporter associated domain
HAEALIFD_01684 1.9e-95 K helix_turn _helix lactose operon repressor
HAEALIFD_01685 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HAEALIFD_01686 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HAEALIFD_01687 0.0 trxB1 1.8.1.9 C Thioredoxin domain
HAEALIFD_01688 6.1e-307 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HAEALIFD_01689 4.3e-239 yhjX EGP Major facilitator Superfamily
HAEALIFD_01690 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HAEALIFD_01691 0.0 yjjP S Threonine/Serine exporter, ThrE
HAEALIFD_01692 1.9e-179 S Amidohydrolase family
HAEALIFD_01693 3.9e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAEALIFD_01694 6.5e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAEALIFD_01695 1e-47 S Protein of unknown function (DUF3073)
HAEALIFD_01696 2.7e-111 T protein histidine kinase activity
HAEALIFD_01697 1e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HAEALIFD_01698 5.1e-28 I transferase activity, transferring acyl groups other than amino-acyl groups
HAEALIFD_01699 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HAEALIFD_01700 1.5e-172 rfbJ M Glycosyl transferase family 2
HAEALIFD_01701 0.0
HAEALIFD_01702 2.5e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HAEALIFD_01703 0.0 3.6.4.12 K Putative DNA-binding domain
HAEALIFD_01704 1.6e-290 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HAEALIFD_01705 4.1e-37 L Transposase DDE domain
HAEALIFD_01706 2.9e-23 L Transposase
HAEALIFD_01707 4.7e-182 L HTH-like domain
HAEALIFD_01708 1e-153 L Transposase, Mutator family
HAEALIFD_01709 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAEALIFD_01710 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAEALIFD_01711 5.9e-244 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAEALIFD_01714 1e-234 patB 4.4.1.8 E Aminotransferase, class I II
HAEALIFD_01715 1.2e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HAEALIFD_01716 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
HAEALIFD_01717 4.4e-118 safC S O-methyltransferase
HAEALIFD_01718 6.6e-184 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
HAEALIFD_01719 3e-71 yraN L Belongs to the UPF0102 family
HAEALIFD_01720 7.2e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
HAEALIFD_01721 5.1e-284 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HAEALIFD_01722 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HAEALIFD_01723 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HAEALIFD_01724 1.6e-157 S Putative ABC-transporter type IV
HAEALIFD_01725 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
HAEALIFD_01726 1.5e-161 V ABC transporter, ATP-binding protein
HAEALIFD_01727 0.0 MV MacB-like periplasmic core domain
HAEALIFD_01728 0.0 phoN I PAP2 superfamily
HAEALIFD_01729 6.1e-132 K helix_turn_helix, Lux Regulon
HAEALIFD_01730 0.0 tcsS2 T Histidine kinase
HAEALIFD_01731 2.2e-265 pip 3.4.11.5 S alpha/beta hydrolase fold
HAEALIFD_01732 1.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAEALIFD_01733 1.9e-167 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
HAEALIFD_01734 3.2e-147 P NLPA lipoprotein
HAEALIFD_01735 5.9e-188 acoA 1.2.4.1 C Dehydrogenase E1 component
HAEALIFD_01736 3.2e-184 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
HAEALIFD_01737 1.6e-205 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAEALIFD_01738 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
HAEALIFD_01739 5.4e-228 mtnE 2.6.1.83 E Aminotransferase class I and II
HAEALIFD_01740 1.2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HAEALIFD_01741 3.1e-194 int L Phage integrase, N-terminal SAM-like domain
HAEALIFD_01742 8.7e-27 S Protein of unknown function (DUF3800)
HAEALIFD_01743 9.7e-30
HAEALIFD_01744 6.8e-08 int L Phage integrase, N-terminal SAM-like domain
HAEALIFD_01745 2.6e-119 dprA LU DNA recombination-mediator protein A
HAEALIFD_01746 8.2e-61 S competence protein
HAEALIFD_01747 3.4e-09
HAEALIFD_01750 4.6e-16
HAEALIFD_01751 1.1e-45
HAEALIFD_01752 1.5e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HAEALIFD_01753 6.6e-64 S Protein of unknown function (DUF4235)
HAEALIFD_01754 1.2e-131 G Phosphoglycerate mutase family
HAEALIFD_01757 1e-190 K Psort location Cytoplasmic, score
HAEALIFD_01758 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
HAEALIFD_01759 0.0 dnaK O Heat shock 70 kDa protein
HAEALIFD_01760 1.4e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAEALIFD_01761 2.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
HAEALIFD_01762 6.8e-87 hspR K transcriptional regulator, MerR family
HAEALIFD_01763 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
HAEALIFD_01764 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
HAEALIFD_01765 3.5e-134 S HAD hydrolase, family IA, variant 3
HAEALIFD_01767 3.5e-126 dedA S SNARE associated Golgi protein
HAEALIFD_01768 2.3e-168 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HAEALIFD_01769 8.6e-59
HAEALIFD_01770 1.6e-130
HAEALIFD_01771 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAEALIFD_01772 8.9e-87 K Transcriptional regulator
HAEALIFD_01774 4.2e-275 xylR 5.3.1.12 G MFS/sugar transport protein
HAEALIFD_01775 5.9e-185 tatD L TatD related DNase
HAEALIFD_01776 0.0 kup P Transport of potassium into the cell
HAEALIFD_01778 1.2e-163 S Glutamine amidotransferase domain
HAEALIFD_01779 2.3e-136 T HD domain
HAEALIFD_01780 2.1e-185 V ABC transporter
HAEALIFD_01781 6.6e-249 V ABC transporter permease
HAEALIFD_01782 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
HAEALIFD_01783 0.0 S Psort location Cytoplasmic, score 8.87
HAEALIFD_01784 7e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HAEALIFD_01785 2e-26 thiS 2.8.1.10 H ThiS family
HAEALIFD_01786 2.5e-79
HAEALIFD_01787 6.9e-187
HAEALIFD_01788 1.7e-207 S Glycosyltransferase, group 2 family protein
HAEALIFD_01789 6.3e-87 yjcF Q Acetyltransferase (GNAT) domain
HAEALIFD_01790 8.4e-156 I Serine aminopeptidase, S33
HAEALIFD_01791 9.3e-53 ybjQ S Putative heavy-metal-binding
HAEALIFD_01792 3e-42
HAEALIFD_01793 2.6e-91 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HAEALIFD_01794 0.0 KL Domain of unknown function (DUF3427)
HAEALIFD_01796 4.6e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAEALIFD_01798 6.9e-104
HAEALIFD_01799 2.5e-162 yicL EG EamA-like transporter family
HAEALIFD_01800 4.6e-207 pldB 3.1.1.5 I Serine aminopeptidase, S33
HAEALIFD_01801 0.0 pip S YhgE Pip domain protein
HAEALIFD_01802 0.0 pip S YhgE Pip domain protein
HAEALIFD_01803 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HAEALIFD_01804 1e-130 fhaA T Protein of unknown function (DUF2662)
HAEALIFD_01805 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HAEALIFD_01806 9.7e-260 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HAEALIFD_01807 2.8e-266 rodA D Belongs to the SEDS family
HAEALIFD_01808 3.7e-263 pbpA M penicillin-binding protein
HAEALIFD_01809 2e-183 T Protein tyrosine kinase
HAEALIFD_01810 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
HAEALIFD_01811 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HAEALIFD_01812 2.6e-233 srtA 3.4.22.70 M Sortase family
HAEALIFD_01813 7.9e-143 S Bacterial protein of unknown function (DUF881)
HAEALIFD_01814 6.9e-67 crgA D Involved in cell division
HAEALIFD_01815 1.6e-257 L ribosomal rna small subunit methyltransferase
HAEALIFD_01816 1.3e-120 L HTH-like domain
HAEALIFD_01817 1.9e-144 gluP 3.4.21.105 S Rhomboid family
HAEALIFD_01818 3.4e-35
HAEALIFD_01819 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HAEALIFD_01820 2e-73 I Sterol carrier protein
HAEALIFD_01821 8.7e-46 L Transposase
HAEALIFD_01822 2.5e-52 L IstB-like ATP binding protein
HAEALIFD_01823 3.9e-43 tnp7109-21 L Integrase core domain
HAEALIFD_01824 4.3e-55 KLT Protein tyrosine kinase
HAEALIFD_01825 7e-125 EGP Transmembrane secretion effector

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)