ORF_ID e_value Gene_name EC_number CAZy COGs Description
DFGLJKNN_00001 2.1e-204 L Transposase and inactivated derivatives IS30 family
DFGLJKNN_00002 6.6e-276 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DFGLJKNN_00003 1.6e-247 V ABC-2 family transporter protein
DFGLJKNN_00004 1.7e-224 V ABC-2 family transporter protein
DFGLJKNN_00005 2.9e-179 V ATPases associated with a variety of cellular activities
DFGLJKNN_00006 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
DFGLJKNN_00007 9.2e-234 T Histidine kinase
DFGLJKNN_00008 3.1e-119 K helix_turn_helix, Lux Regulon
DFGLJKNN_00009 1.1e-115 MA20_27875 P Protein of unknown function DUF47
DFGLJKNN_00010 3.4e-189 pit P Phosphate transporter family
DFGLJKNN_00011 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
DFGLJKNN_00012 3.3e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DFGLJKNN_00013 4e-181 L HTH-like domain
DFGLJKNN_00014 2.6e-112 bepIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
DFGLJKNN_00015 4.5e-85
DFGLJKNN_00016 1.9e-87 L Transposase
DFGLJKNN_00017 2.1e-25 L Transposase
DFGLJKNN_00018 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DFGLJKNN_00019 1.3e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DFGLJKNN_00020 1.7e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DFGLJKNN_00021 2.9e-108 3.4.13.21 E Peptidase family S51
DFGLJKNN_00022 4.2e-135 L Phage integrase family
DFGLJKNN_00024 3.6e-219 ykiI
DFGLJKNN_00025 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DFGLJKNN_00026 1.9e-127 3.6.1.13 L NUDIX domain
DFGLJKNN_00027 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
DFGLJKNN_00028 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DFGLJKNN_00029 9.2e-120 pdtaR T Response regulator receiver domain protein
DFGLJKNN_00031 1.8e-110 aspA 3.6.1.13 L NUDIX domain
DFGLJKNN_00032 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
DFGLJKNN_00033 1.3e-179 terC P Integral membrane protein, TerC family
DFGLJKNN_00034 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DFGLJKNN_00035 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DFGLJKNN_00036 3.3e-243 rpsA J Ribosomal protein S1
DFGLJKNN_00037 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DFGLJKNN_00038 7.4e-173 P Zinc-uptake complex component A periplasmic
DFGLJKNN_00039 1.8e-164 znuC P ATPases associated with a variety of cellular activities
DFGLJKNN_00040 4.3e-139 znuB U ABC 3 transport family
DFGLJKNN_00041 1.2e-82 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DFGLJKNN_00042 5.1e-102 carD K CarD-like/TRCF domain
DFGLJKNN_00043 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DFGLJKNN_00044 1.9e-127 T Response regulator receiver domain protein
DFGLJKNN_00045 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DFGLJKNN_00046 3.6e-72 rulA 3.4.21.88 KT Peptidase S24-like
DFGLJKNN_00047 7.7e-129 ctsW S Phosphoribosyl transferase domain
DFGLJKNN_00048 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
DFGLJKNN_00049 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
DFGLJKNN_00050 4.5e-264
DFGLJKNN_00051 0.0 S Glycosyl transferase, family 2
DFGLJKNN_00052 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DFGLJKNN_00053 2.4e-270 K Cell envelope-related transcriptional attenuator domain
DFGLJKNN_00054 0.0 D FtsK/SpoIIIE family
DFGLJKNN_00055 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DFGLJKNN_00056 7.3e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DFGLJKNN_00057 2e-142 yplQ S Haemolysin-III related
DFGLJKNN_00058 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DFGLJKNN_00059 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
DFGLJKNN_00060 7.9e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
DFGLJKNN_00061 4.7e-97
DFGLJKNN_00063 1.2e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DFGLJKNN_00064 4.4e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
DFGLJKNN_00065 9.4e-101 divIC D Septum formation initiator
DFGLJKNN_00066 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DFGLJKNN_00067 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
DFGLJKNN_00068 8.2e-298 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
DFGLJKNN_00069 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DFGLJKNN_00070 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DFGLJKNN_00071 3.9e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
DFGLJKNN_00072 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
DFGLJKNN_00073 3.6e-151 GM ABC-2 type transporter
DFGLJKNN_00074 4.3e-197 GM GDP-mannose 4,6 dehydratase
DFGLJKNN_00075 1.5e-129 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DFGLJKNN_00078 2.9e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
DFGLJKNN_00079 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DFGLJKNN_00080 2.1e-207 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DFGLJKNN_00081 0.0 S Uncharacterised protein family (UPF0182)
DFGLJKNN_00082 6.7e-232 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
DFGLJKNN_00083 7.6e-197
DFGLJKNN_00084 1.9e-152 ytrE V ATPases associated with a variety of cellular activities
DFGLJKNN_00085 3.7e-191 V N-Acetylmuramoyl-L-alanine amidase
DFGLJKNN_00086 1.2e-258 argE E Peptidase dimerisation domain
DFGLJKNN_00087 4.2e-104 S Protein of unknown function (DUF3043)
DFGLJKNN_00088 3.2e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DFGLJKNN_00089 9.4e-144 S Domain of unknown function (DUF4191)
DFGLJKNN_00090 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
DFGLJKNN_00091 1.3e-18
DFGLJKNN_00093 5.1e-19
DFGLJKNN_00096 8.8e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DFGLJKNN_00097 5.7e-211 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DFGLJKNN_00098 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DFGLJKNN_00099 0.0 S Tetratricopeptide repeat
DFGLJKNN_00100 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DFGLJKNN_00101 1.4e-68 2.8.2.22 S Arylsulfotransferase Ig-like domain
DFGLJKNN_00102 2.4e-139 bioM P ATPases associated with a variety of cellular activities
DFGLJKNN_00103 2e-213 E Aminotransferase class I and II
DFGLJKNN_00104 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
DFGLJKNN_00106 1.1e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DFGLJKNN_00107 0.0 ecfA GP ABC transporter, ATP-binding protein
DFGLJKNN_00108 5.7e-256 EGP Major facilitator Superfamily
DFGLJKNN_00110 2.2e-257 rarA L Recombination factor protein RarA
DFGLJKNN_00111 0.0 L DEAD DEAH box helicase
DFGLJKNN_00112 6e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
DFGLJKNN_00113 4.1e-198 gluD E Binding-protein-dependent transport system inner membrane component
DFGLJKNN_00114 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
DFGLJKNN_00115 9.5e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
DFGLJKNN_00116 3.6e-140 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
DFGLJKNN_00117 8.2e-93 S Aminoacyl-tRNA editing domain
DFGLJKNN_00118 3.3e-81 K helix_turn_helix, Lux Regulon
DFGLJKNN_00119 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DFGLJKNN_00120 8.7e-262 hisS 6.1.1.21 J Histidyl-tRNA synthetase
DFGLJKNN_00121 5.1e-217 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
DFGLJKNN_00125 0.0 clpC O ATPase family associated with various cellular activities (AAA)
DFGLJKNN_00126 4.7e-185 uspA T Belongs to the universal stress protein A family
DFGLJKNN_00127 8.3e-204 S Protein of unknown function (DUF3027)
DFGLJKNN_00128 1e-66 cspB K 'Cold-shock' DNA-binding domain
DFGLJKNN_00129 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DFGLJKNN_00130 1.6e-134 KT Response regulator receiver domain protein
DFGLJKNN_00131 4.9e-162
DFGLJKNN_00132 1.7e-10 S Proteins of 100 residues with WXG
DFGLJKNN_00133 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DFGLJKNN_00134 8.3e-44 cspA K 'Cold-shock' DNA-binding domain
DFGLJKNN_00135 7.6e-71 S LytR cell envelope-related transcriptional attenuator
DFGLJKNN_00136 1.1e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DFGLJKNN_00137 2.3e-196 moxR S ATPase family associated with various cellular activities (AAA)
DFGLJKNN_00138 7.2e-178 S Protein of unknown function DUF58
DFGLJKNN_00139 2.4e-93
DFGLJKNN_00140 4.4e-189 S von Willebrand factor (vWF) type A domain
DFGLJKNN_00141 1.4e-147 S von Willebrand factor (vWF) type A domain
DFGLJKNN_00142 2.7e-74
DFGLJKNN_00144 2.9e-290 S PGAP1-like protein
DFGLJKNN_00145 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
DFGLJKNN_00146 0.0 S Lysylphosphatidylglycerol synthase TM region
DFGLJKNN_00147 8.1e-42 hup L Belongs to the bacterial histone-like protein family
DFGLJKNN_00148 2.2e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DFGLJKNN_00149 9.2e-11 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
DFGLJKNN_00150 2.2e-156 hisN 3.1.3.25 G Inositol monophosphatase family
DFGLJKNN_00151 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
DFGLJKNN_00152 0.0 arc O AAA ATPase forming ring-shaped complexes
DFGLJKNN_00153 1.6e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
DFGLJKNN_00154 5.6e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DFGLJKNN_00155 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DFGLJKNN_00156 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DFGLJKNN_00157 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DFGLJKNN_00158 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DFGLJKNN_00159 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
DFGLJKNN_00160 1.8e-175 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DFGLJKNN_00162 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DFGLJKNN_00163 0.0 ctpE P E1-E2 ATPase
DFGLJKNN_00164 2e-109
DFGLJKNN_00165 6.5e-248 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DFGLJKNN_00166 3.7e-129 S Protein of unknown function (DUF3159)
DFGLJKNN_00167 2.1e-138 S Protein of unknown function (DUF3710)
DFGLJKNN_00168 1.8e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
DFGLJKNN_00169 5.2e-262 pepC 3.4.22.40 E Peptidase C1-like family
DFGLJKNN_00170 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
DFGLJKNN_00171 0.0 oppD P Belongs to the ABC transporter superfamily
DFGLJKNN_00172 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
DFGLJKNN_00173 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
DFGLJKNN_00174 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
DFGLJKNN_00175 7.3e-42
DFGLJKNN_00176 1.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
DFGLJKNN_00177 5.5e-197 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
DFGLJKNN_00178 5.5e-92
DFGLJKNN_00179 0.0 typA T Elongation factor G C-terminus
DFGLJKNN_00180 1.4e-237 iscS1 2.8.1.7 E Aminotransferase class-V
DFGLJKNN_00181 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
DFGLJKNN_00182 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
DFGLJKNN_00183 9.8e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DFGLJKNN_00184 1.1e-149 nrtR 3.6.1.55 F NUDIX hydrolase
DFGLJKNN_00185 5.4e-113 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DFGLJKNN_00186 3.2e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DFGLJKNN_00187 7e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
DFGLJKNN_00188 2.9e-179 xerD D recombinase XerD
DFGLJKNN_00189 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DFGLJKNN_00190 2.1e-25 rpmI J Ribosomal protein L35
DFGLJKNN_00191 2.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DFGLJKNN_00192 1.9e-07 S Spermine/spermidine synthase domain
DFGLJKNN_00193 8e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
DFGLJKNN_00194 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DFGLJKNN_00195 2.4e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DFGLJKNN_00197 2e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DFGLJKNN_00198 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
DFGLJKNN_00199 2e-64
DFGLJKNN_00200 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
DFGLJKNN_00201 1.4e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DFGLJKNN_00202 5.7e-191 V Acetyltransferase (GNAT) domain
DFGLJKNN_00203 5.4e-228 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
DFGLJKNN_00204 2.8e-243 yxbA 6.3.1.12 S ATP-grasp
DFGLJKNN_00205 1.6e-128 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
DFGLJKNN_00206 0.0 smc D Required for chromosome condensation and partitioning
DFGLJKNN_00207 8e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
DFGLJKNN_00209 9.6e-97 3.6.1.55 F NUDIX domain
DFGLJKNN_00210 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
DFGLJKNN_00211 0.0 P Belongs to the ABC transporter superfamily
DFGLJKNN_00212 1.9e-190 dppC EP Binding-protein-dependent transport system inner membrane component
DFGLJKNN_00213 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
DFGLJKNN_00214 3.7e-304 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
DFGLJKNN_00215 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
DFGLJKNN_00216 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DFGLJKNN_00217 7e-217 GK ROK family
DFGLJKNN_00218 3.4e-132 cutC P Participates in the control of copper homeostasis
DFGLJKNN_00219 1.3e-224 GK ROK family
DFGLJKNN_00220 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
DFGLJKNN_00221 4.4e-236 G Major Facilitator Superfamily
DFGLJKNN_00222 6.6e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DFGLJKNN_00224 1.3e-37
DFGLJKNN_00225 3.9e-160 ftsQ 6.3.2.4 D Cell division protein FtsQ
DFGLJKNN_00226 6.1e-296 murC 6.3.2.8 M Belongs to the MurCDEF family
DFGLJKNN_00227 6.5e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DFGLJKNN_00228 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
DFGLJKNN_00229 1.2e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DFGLJKNN_00230 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DFGLJKNN_00231 3.1e-284 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DFGLJKNN_00232 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DFGLJKNN_00233 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
DFGLJKNN_00234 2.5e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DFGLJKNN_00235 1.1e-193 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DFGLJKNN_00236 1.3e-90 mraZ K Belongs to the MraZ family
DFGLJKNN_00237 0.0 L DNA helicase
DFGLJKNN_00238 3.2e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DFGLJKNN_00239 1.1e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DFGLJKNN_00240 1.5e-43 M Lysin motif
DFGLJKNN_00241 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DFGLJKNN_00242 1.2e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DFGLJKNN_00243 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
DFGLJKNN_00244 3.2e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DFGLJKNN_00245 2.6e-169
DFGLJKNN_00246 4.1e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
DFGLJKNN_00247 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
DFGLJKNN_00248 1.3e-172 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DFGLJKNN_00249 1e-60 EGP Major facilitator Superfamily
DFGLJKNN_00250 3.2e-245 S Domain of unknown function (DUF5067)
DFGLJKNN_00251 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
DFGLJKNN_00252 4.9e-284 S Uncharacterized protein conserved in bacteria (DUF2252)
DFGLJKNN_00253 1.2e-129 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
DFGLJKNN_00254 1.1e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DFGLJKNN_00255 5.9e-113
DFGLJKNN_00256 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
DFGLJKNN_00257 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DFGLJKNN_00258 1.1e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DFGLJKNN_00259 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DFGLJKNN_00260 7.8e-08 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
DFGLJKNN_00262 1.2e-76 yneG S Domain of unknown function (DUF4186)
DFGLJKNN_00263 6.4e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
DFGLJKNN_00264 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
DFGLJKNN_00265 3.4e-202 K WYL domain
DFGLJKNN_00267 0.0 4.2.1.53 S MCRA family
DFGLJKNN_00268 1.6e-46 yhbY J CRS1_YhbY
DFGLJKNN_00269 7.6e-106 S zinc-ribbon domain
DFGLJKNN_00270 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
DFGLJKNN_00271 4.5e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
DFGLJKNN_00272 6.5e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
DFGLJKNN_00273 1.5e-191 ywqG S Domain of unknown function (DUF1963)
DFGLJKNN_00274 5.3e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DFGLJKNN_00275 3.6e-140 recO L Involved in DNA repair and RecF pathway recombination
DFGLJKNN_00276 1.2e-291 I acetylesterase activity
DFGLJKNN_00277 6.1e-236 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DFGLJKNN_00278 1.5e-222 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DFGLJKNN_00279 1.5e-201 2.7.11.1 NU Tfp pilus assembly protein FimV
DFGLJKNN_00281 8.7e-24
DFGLJKNN_00282 5.7e-19
DFGLJKNN_00283 1.4e-149 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
DFGLJKNN_00284 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DFGLJKNN_00285 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
DFGLJKNN_00286 9.2e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
DFGLJKNN_00287 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
DFGLJKNN_00288 1.1e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DFGLJKNN_00289 3.7e-137 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
DFGLJKNN_00290 6e-63
DFGLJKNN_00292 2e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DFGLJKNN_00293 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DFGLJKNN_00294 9.7e-90 3.1.21.3 V DivIVA protein
DFGLJKNN_00295 2.1e-42 yggT S YGGT family
DFGLJKNN_00296 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DFGLJKNN_00297 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DFGLJKNN_00298 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DFGLJKNN_00299 7.9e-301 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
DFGLJKNN_00300 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
DFGLJKNN_00301 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DFGLJKNN_00302 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DFGLJKNN_00303 1.3e-84
DFGLJKNN_00304 6.9e-231 O AAA domain (Cdc48 subfamily)
DFGLJKNN_00305 5.4e-164 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DFGLJKNN_00306 4e-60 S Thiamine-binding protein
DFGLJKNN_00307 2.6e-194 K helix_turn _helix lactose operon repressor
DFGLJKNN_00308 5.7e-47 S Protein of unknown function (DUF3052)
DFGLJKNN_00309 1.7e-151 lon T Belongs to the peptidase S16 family
DFGLJKNN_00310 6.6e-279 S Zincin-like metallopeptidase
DFGLJKNN_00311 9.6e-283 uvrD2 3.6.4.12 L DNA helicase
DFGLJKNN_00312 2.7e-237 mphA S Aminoglycoside phosphotransferase
DFGLJKNN_00313 6.1e-32 S Protein of unknown function (DUF3107)
DFGLJKNN_00314 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
DFGLJKNN_00315 7.6e-115 S Vitamin K epoxide reductase
DFGLJKNN_00316 1.5e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
DFGLJKNN_00317 1.1e-152 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DFGLJKNN_00318 1.8e-168 S Patatin-like phospholipase
DFGLJKNN_00319 0.0 V ABC transporter transmembrane region
DFGLJKNN_00320 0.0 V ABC transporter, ATP-binding protein
DFGLJKNN_00321 2.9e-88 K MarR family
DFGLJKNN_00322 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
DFGLJKNN_00323 3.4e-261 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
DFGLJKNN_00324 1.2e-166
DFGLJKNN_00325 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
DFGLJKNN_00327 4.3e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DFGLJKNN_00328 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
DFGLJKNN_00329 2.1e-271 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DFGLJKNN_00330 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DFGLJKNN_00331 5.6e-203 S Endonuclease/Exonuclease/phosphatase family
DFGLJKNN_00333 3.1e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DFGLJKNN_00334 1.2e-255 cdr OP Sulfurtransferase TusA
DFGLJKNN_00335 2.6e-149 moeB 2.7.7.80 H ThiF family
DFGLJKNN_00336 5e-131 tmp1 S Domain of unknown function (DUF4391)
DFGLJKNN_00337 2.3e-37 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DFGLJKNN_00338 4.5e-29 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DFGLJKNN_00339 8.3e-229 aspB E Aminotransferase class-V
DFGLJKNN_00340 2e-112 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
DFGLJKNN_00341 2e-269 S zinc finger
DFGLJKNN_00342 2.6e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DFGLJKNN_00343 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DFGLJKNN_00344 2.1e-291 O Subtilase family
DFGLJKNN_00345 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
DFGLJKNN_00346 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DFGLJKNN_00347 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DFGLJKNN_00348 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DFGLJKNN_00349 1.4e-59 L Transposase
DFGLJKNN_00350 6.4e-24 relB L RelB antitoxin
DFGLJKNN_00351 2.7e-10 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
DFGLJKNN_00352 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
DFGLJKNN_00353 2.9e-66 gsiA P ATPase activity
DFGLJKNN_00354 1.3e-257 G Major Facilitator Superfamily
DFGLJKNN_00355 8.6e-159 K -acetyltransferase
DFGLJKNN_00356 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
DFGLJKNN_00357 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
DFGLJKNN_00358 1.8e-267 KLT Protein tyrosine kinase
DFGLJKNN_00359 0.0 S Fibronectin type 3 domain
DFGLJKNN_00360 1.8e-232 S ATPase family associated with various cellular activities (AAA)
DFGLJKNN_00361 1.7e-230 S Protein of unknown function DUF58
DFGLJKNN_00362 0.0 E Transglutaminase-like superfamily
DFGLJKNN_00363 2e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
DFGLJKNN_00364 1.1e-67 B Belongs to the OprB family
DFGLJKNN_00365 1.3e-96 T Forkhead associated domain
DFGLJKNN_00366 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DFGLJKNN_00367 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DFGLJKNN_00368 9.6e-102
DFGLJKNN_00369 4.2e-185 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
DFGLJKNN_00370 6.7e-68 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
DFGLJKNN_00371 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DFGLJKNN_00373 1.1e-06 S Membrane
DFGLJKNN_00374 9.9e-109
DFGLJKNN_00375 1.2e-252 S UPF0210 protein
DFGLJKNN_00376 4.2e-43 gcvR T Belongs to the UPF0237 family
DFGLJKNN_00377 1.1e-242 EGP Sugar (and other) transporter
DFGLJKNN_00378 4.8e-165 tetP J elongation factor G
DFGLJKNN_00379 1.4e-131 tetP J elongation factor G
DFGLJKNN_00380 5.9e-228 S HipA-like C-terminal domain
DFGLJKNN_00381 1.1e-46
DFGLJKNN_00382 2e-60
DFGLJKNN_00383 1.5e-81
DFGLJKNN_00384 0.0 topB 5.99.1.2 L DNA topoisomerase
DFGLJKNN_00385 2.7e-85
DFGLJKNN_00386 3e-55
DFGLJKNN_00387 1.8e-40 K Protein of unknown function (DUF2442)
DFGLJKNN_00388 6.9e-52 S Bacterial mobilisation protein (MobC)
DFGLJKNN_00389 5.4e-279 ltrBE1 U Relaxase/Mobilisation nuclease domain
DFGLJKNN_00390 1.8e-163 S Protein of unknown function (DUF3801)
DFGLJKNN_00391 1.7e-284
DFGLJKNN_00393 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DFGLJKNN_00394 3.2e-39
DFGLJKNN_00395 9.3e-31
DFGLJKNN_00396 0.0 U Type IV secretory system Conjugative DNA transfer
DFGLJKNN_00398 3e-09
DFGLJKNN_00399 2.4e-101 dam2 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
DFGLJKNN_00400 5.9e-101 K DNA binding
DFGLJKNN_00401 3.2e-129
DFGLJKNN_00402 3.6e-14 U Type IV secretory system Conjugative DNA transfer
DFGLJKNN_00403 5.4e-205 isp2 3.2.1.96 M CHAP domain
DFGLJKNN_00404 0.0 trsE U type IV secretory pathway VirB4
DFGLJKNN_00405 1e-62 S PrgI family protein
DFGLJKNN_00406 3.3e-139
DFGLJKNN_00407 8.9e-26
DFGLJKNN_00408 0.0 XK27_00515 D Cell surface antigen C-terminus
DFGLJKNN_00409 2.5e-87
DFGLJKNN_00410 6.9e-19
DFGLJKNN_00411 1.6e-17 S Maff2 family
DFGLJKNN_00412 0.0 U Type IV secretory system Conjugative DNA transfer
DFGLJKNN_00413 1.4e-57 S Protein of unknown function (DUF3801)
DFGLJKNN_00414 9.5e-35 S Psort location Cytoplasmic, score
DFGLJKNN_00415 3.6e-165 L Psort location Cytoplasmic, score
DFGLJKNN_00416 6.7e-229 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
DFGLJKNN_00417 4e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
DFGLJKNN_00418 3.1e-139 glpR K DeoR C terminal sensor domain
DFGLJKNN_00419 3.3e-226 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
DFGLJKNN_00420 2.5e-219 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
DFGLJKNN_00421 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DFGLJKNN_00422 3.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
DFGLJKNN_00423 2.2e-119 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
DFGLJKNN_00424 2e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DFGLJKNN_00425 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
DFGLJKNN_00426 1.1e-240 S Uncharacterized conserved protein (DUF2183)
DFGLJKNN_00427 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
DFGLJKNN_00428 0.0 enhA_2 S L,D-transpeptidase catalytic domain
DFGLJKNN_00429 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
DFGLJKNN_00430 4.9e-159 mhpC I Alpha/beta hydrolase family
DFGLJKNN_00431 1.4e-118 F Domain of unknown function (DUF4916)
DFGLJKNN_00432 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
DFGLJKNN_00433 5e-179 S G5
DFGLJKNN_00434 8.2e-25
DFGLJKNN_00435 1.7e-213 T regulation of circadian rhythm
DFGLJKNN_00436 4.1e-115 V Abi-like protein
DFGLJKNN_00437 0.0 L DEAD-like helicases superfamily
DFGLJKNN_00438 1.2e-61
DFGLJKNN_00439 2.6e-63
DFGLJKNN_00440 1.4e-42
DFGLJKNN_00441 2.8e-23 L Transposase, Mutator family
DFGLJKNN_00442 2.7e-159 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
DFGLJKNN_00443 2.2e-195 L Integrase core domain
DFGLJKNN_00444 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
DFGLJKNN_00445 3.1e-65 rplQ J Ribosomal protein L17
DFGLJKNN_00446 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DFGLJKNN_00447 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DFGLJKNN_00448 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DFGLJKNN_00449 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DFGLJKNN_00450 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DFGLJKNN_00451 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DFGLJKNN_00452 8.9e-248 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DFGLJKNN_00453 2.7e-63 rplO J binds to the 23S rRNA
DFGLJKNN_00454 1e-24 rpmD J Ribosomal protein L30p/L7e
DFGLJKNN_00455 1.9e-98 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DFGLJKNN_00456 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DFGLJKNN_00457 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DFGLJKNN_00458 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DFGLJKNN_00459 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DFGLJKNN_00460 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DFGLJKNN_00461 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DFGLJKNN_00462 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DFGLJKNN_00463 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DFGLJKNN_00464 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
DFGLJKNN_00465 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DFGLJKNN_00466 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DFGLJKNN_00467 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DFGLJKNN_00468 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DFGLJKNN_00469 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DFGLJKNN_00470 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DFGLJKNN_00471 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
DFGLJKNN_00472 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DFGLJKNN_00473 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
DFGLJKNN_00474 3e-14 ywiC S YwiC-like protein
DFGLJKNN_00475 1.9e-111 ywiC S YwiC-like protein
DFGLJKNN_00476 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
DFGLJKNN_00477 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DFGLJKNN_00478 3.1e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
DFGLJKNN_00479 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DFGLJKNN_00480 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
DFGLJKNN_00481 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DFGLJKNN_00482 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
DFGLJKNN_00483 1.8e-120
DFGLJKNN_00484 1.1e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
DFGLJKNN_00485 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
DFGLJKNN_00487 6e-241 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DFGLJKNN_00488 1.4e-225 dapC E Aminotransferase class I and II
DFGLJKNN_00489 9e-61 fdxA C 4Fe-4S binding domain
DFGLJKNN_00490 7.4e-217 murB 1.3.1.98 M Cell wall formation
DFGLJKNN_00491 1.9e-25 rpmG J Ribosomal protein L33
DFGLJKNN_00495 1.2e-51 moxR S ATPase family associated with various cellular activities (AAA)
DFGLJKNN_00496 2.1e-132 bla1 3.5.2.6 V Beta-lactamase enzyme family
DFGLJKNN_00497 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DFGLJKNN_00498 6.3e-148
DFGLJKNN_00499 2.3e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
DFGLJKNN_00500 1.8e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
DFGLJKNN_00501 3.2e-38 fmdB S Putative regulatory protein
DFGLJKNN_00502 5.6e-110 flgA NO SAF
DFGLJKNN_00503 9.6e-42
DFGLJKNN_00504 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
DFGLJKNN_00505 6.1e-238 T Forkhead associated domain
DFGLJKNN_00507 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DFGLJKNN_00508 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DFGLJKNN_00509 1.8e-184 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
DFGLJKNN_00510 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
DFGLJKNN_00511 8.8e-222 pbuO S Permease family
DFGLJKNN_00512 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DFGLJKNN_00513 9.2e-170 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DFGLJKNN_00514 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DFGLJKNN_00515 6.2e-180 pstA P Phosphate transport system permease
DFGLJKNN_00516 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
DFGLJKNN_00517 3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
DFGLJKNN_00518 3.7e-128 KT Transcriptional regulatory protein, C terminal
DFGLJKNN_00519 8.5e-246 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
DFGLJKNN_00520 8.7e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DFGLJKNN_00521 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DFGLJKNN_00522 1e-105 K helix_turn_helix, Arsenical Resistance Operon Repressor
DFGLJKNN_00523 1.1e-243 EGP Major facilitator Superfamily
DFGLJKNN_00524 1.5e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DFGLJKNN_00525 1.4e-168 L Excalibur calcium-binding domain
DFGLJKNN_00526 1.2e-268 pepC 3.4.22.40 E Peptidase C1-like family
DFGLJKNN_00527 3.1e-52 D nuclear chromosome segregation
DFGLJKNN_00528 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DFGLJKNN_00529 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DFGLJKNN_00530 1.8e-187 yfiH Q Multi-copper polyphenol oxidoreductase laccase
DFGLJKNN_00531 0.0 yegQ O Peptidase family U32 C-terminal domain
DFGLJKNN_00532 3.2e-95 L Transposase and inactivated derivatives IS30 family
DFGLJKNN_00533 3.9e-167 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
DFGLJKNN_00534 2.2e-41 nrdH O Glutaredoxin
DFGLJKNN_00535 9.5e-98 nrdI F Probably involved in ribonucleotide reductase function
DFGLJKNN_00536 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DFGLJKNN_00537 1.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DFGLJKNN_00538 1.3e-73 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DFGLJKNN_00539 0.0 S Predicted membrane protein (DUF2207)
DFGLJKNN_00540 1e-91 lemA S LemA family
DFGLJKNN_00541 4.2e-55 xylR K purine nucleotide biosynthetic process
DFGLJKNN_00542 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DFGLJKNN_00543 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DFGLJKNN_00544 8.9e-119
DFGLJKNN_00545 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
DFGLJKNN_00547 9.3e-161 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
DFGLJKNN_00548 2.5e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DFGLJKNN_00549 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
DFGLJKNN_00550 7.2e-308 pccB I Carboxyl transferase domain
DFGLJKNN_00551 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
DFGLJKNN_00552 4.2e-93 bioY S BioY family
DFGLJKNN_00553 4.4e-152 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
DFGLJKNN_00554 0.0
DFGLJKNN_00555 5.9e-146 QT PucR C-terminal helix-turn-helix domain
DFGLJKNN_00556 9.5e-132 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DFGLJKNN_00557 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DFGLJKNN_00558 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DFGLJKNN_00559 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DFGLJKNN_00560 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DFGLJKNN_00561 1.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DFGLJKNN_00562 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DFGLJKNN_00563 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DFGLJKNN_00565 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
DFGLJKNN_00566 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DFGLJKNN_00568 5.7e-09 K BetR domain
DFGLJKNN_00573 4.9e-26
DFGLJKNN_00574 4.6e-15
DFGLJKNN_00576 3.7e-17 S Helix-turn-helix domain
DFGLJKNN_00577 1.4e-98 L HNH endonuclease
DFGLJKNN_00578 2.3e-40
DFGLJKNN_00579 1.4e-235 S Terminase
DFGLJKNN_00580 6.7e-161 S Phage portal protein
DFGLJKNN_00581 7.5e-214 S Caudovirus prohead serine protease
DFGLJKNN_00582 3.3e-42
DFGLJKNN_00583 6.7e-36
DFGLJKNN_00584 2.6e-60
DFGLJKNN_00585 8.3e-55
DFGLJKNN_00586 4.5e-37
DFGLJKNN_00587 5.4e-150 NT phage tail tape measure protein
DFGLJKNN_00588 1.4e-108
DFGLJKNN_00590 2.3e-10
DFGLJKNN_00591 7.1e-75 3.2.1.20, 3.5.1.28 GH31 V N-acetylmuramoyl-L-alanine amidase
DFGLJKNN_00592 3.2e-11 xhlB S SPP1 phage holin
DFGLJKNN_00593 3.6e-90 L Phage integrase family
DFGLJKNN_00596 4.6e-35
DFGLJKNN_00597 0.0 K RNA polymerase II activating transcription factor binding
DFGLJKNN_00598 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
DFGLJKNN_00599 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DFGLJKNN_00601 1.3e-102 mntP P Probably functions as a manganese efflux pump
DFGLJKNN_00602 1.4e-125
DFGLJKNN_00603 2e-135 KT Transcriptional regulatory protein, C terminal
DFGLJKNN_00604 1.9e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DFGLJKNN_00605 4.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
DFGLJKNN_00606 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DFGLJKNN_00607 0.0 S domain protein
DFGLJKNN_00608 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
DFGLJKNN_00609 2.4e-90 lrp_3 K helix_turn_helix ASNC type
DFGLJKNN_00610 3e-234 E Aminotransferase class I and II
DFGLJKNN_00611 1.7e-309 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DFGLJKNN_00612 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
DFGLJKNN_00613 3.3e-52 S Protein of unknown function (DUF2469)
DFGLJKNN_00614 5.1e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
DFGLJKNN_00615 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DFGLJKNN_00616 1.1e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DFGLJKNN_00617 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DFGLJKNN_00618 6.2e-61 V ABC transporter
DFGLJKNN_00619 3.3e-59 V ABC transporter
DFGLJKNN_00620 6.9e-156 spoU 2.1.1.185 J RNA methyltransferase TrmH family
DFGLJKNN_00621 5.9e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DFGLJKNN_00622 1.3e-214 rmuC S RmuC family
DFGLJKNN_00623 9.6e-43 csoR S Metal-sensitive transcriptional repressor
DFGLJKNN_00624 0.0 pacS 3.6.3.54 P E1-E2 ATPase
DFGLJKNN_00625 0.0 ubiB S ABC1 family
DFGLJKNN_00626 3.5e-19 S granule-associated protein
DFGLJKNN_00627 2.2e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
DFGLJKNN_00628 1.7e-282 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
DFGLJKNN_00629 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DFGLJKNN_00630 8.2e-252 dinF V MatE
DFGLJKNN_00631 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
DFGLJKNN_00632 1e-54 glnB K Nitrogen regulatory protein P-II
DFGLJKNN_00633 1.3e-219 amt U Ammonium Transporter Family
DFGLJKNN_00634 5.6e-204 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DFGLJKNN_00636 2.7e-116 icaR K Bacterial regulatory proteins, tetR family
DFGLJKNN_00637 1e-195 XK27_01805 M Glycosyltransferase like family 2
DFGLJKNN_00638 0.0 S Glycosyl hydrolases related to GH101 family, GH129
DFGLJKNN_00639 3.2e-305 pepD E Peptidase family C69
DFGLJKNN_00641 3.7e-19 XK26_04485 P Cobalt transport protein
DFGLJKNN_00642 1.2e-70 XK26_04485 P Cobalt transport protein
DFGLJKNN_00643 1.6e-84
DFGLJKNN_00644 0.0 V ABC transporter transmembrane region
DFGLJKNN_00645 1.8e-301 V ABC transporter, ATP-binding protein
DFGLJKNN_00646 1.7e-81 K Winged helix DNA-binding domain
DFGLJKNN_00647 3.9e-73 E IrrE N-terminal-like domain
DFGLJKNN_00649 2.6e-160 S Sucrose-6F-phosphate phosphohydrolase
DFGLJKNN_00650 4e-237 S Putative ABC-transporter type IV
DFGLJKNN_00651 5.9e-80
DFGLJKNN_00652 1.5e-33 Q phosphatase activity
DFGLJKNN_00653 3e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
DFGLJKNN_00654 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
DFGLJKNN_00655 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
DFGLJKNN_00656 2.1e-249 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DFGLJKNN_00657 4.6e-67 S haloacid dehalogenase-like hydrolase
DFGLJKNN_00658 9.6e-11 S haloacid dehalogenase-like hydrolase
DFGLJKNN_00659 3.6e-131 yydK K UTRA
DFGLJKNN_00660 1.3e-70 S FMN_bind
DFGLJKNN_00661 5.7e-149 macB V ABC transporter, ATP-binding protein
DFGLJKNN_00662 4.1e-202 Z012_06715 V FtsX-like permease family
DFGLJKNN_00663 9.7e-223 macB_2 V ABC transporter permease
DFGLJKNN_00664 6e-233 S Predicted membrane protein (DUF2318)
DFGLJKNN_00665 5.4e-108 tpd P Fe2+ transport protein
DFGLJKNN_00666 1.1e-306 efeU_1 P Iron permease FTR1 family
DFGLJKNN_00667 5.9e-22 G MFS/sugar transport protein
DFGLJKNN_00668 1.7e-198 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DFGLJKNN_00669 1.8e-115 S Fic/DOC family
DFGLJKNN_00670 1.1e-290 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DFGLJKNN_00671 5e-38 ptsH G PTS HPr component phosphorylation site
DFGLJKNN_00672 4.6e-197 K helix_turn _helix lactose operon repressor
DFGLJKNN_00673 1.7e-210 holB 2.7.7.7 L DNA polymerase III
DFGLJKNN_00674 2.1e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DFGLJKNN_00675 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DFGLJKNN_00676 1.5e-187 3.6.1.27 I PAP2 superfamily
DFGLJKNN_00677 0.0 vpr M PA domain
DFGLJKNN_00678 3e-121 yplQ S Haemolysin-III related
DFGLJKNN_00679 9.3e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
DFGLJKNN_00680 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DFGLJKNN_00681 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DFGLJKNN_00682 1e-278 S Calcineurin-like phosphoesterase
DFGLJKNN_00683 1.9e-14 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
DFGLJKNN_00684 1.5e-280 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
DFGLJKNN_00685 1.7e-116
DFGLJKNN_00686 1.7e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DFGLJKNN_00688 1.8e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
DFGLJKNN_00689 5.3e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
DFGLJKNN_00690 1.9e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DFGLJKNN_00691 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
DFGLJKNN_00692 2.4e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
DFGLJKNN_00693 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
DFGLJKNN_00694 3.2e-41 S Protein of unknown function (DUF4244)
DFGLJKNN_00695 9.5e-79 gspF NU Type II secretion system (T2SS), protein F
DFGLJKNN_00696 2.8e-120 U Type ii secretion system
DFGLJKNN_00697 3.4e-191 cpaF U Type II IV secretion system protein
DFGLJKNN_00698 1.3e-151 cpaE D bacterial-type flagellum organization
DFGLJKNN_00700 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DFGLJKNN_00701 6.3e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
DFGLJKNN_00702 5e-91
DFGLJKNN_00703 2.1e-42 cbiM P PDGLE domain
DFGLJKNN_00704 2.2e-57 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DFGLJKNN_00705 2e-208 S Glycosyltransferase, group 2 family protein
DFGLJKNN_00706 7.2e-275
DFGLJKNN_00707 8.7e-27 thiS 2.8.1.10 H ThiS family
DFGLJKNN_00708 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DFGLJKNN_00709 0.0 S Psort location Cytoplasmic, score 8.87
DFGLJKNN_00710 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
DFGLJKNN_00711 2.6e-245 V ABC transporter permease
DFGLJKNN_00712 4.9e-182 V ABC transporter
DFGLJKNN_00713 4.6e-137 T HD domain
DFGLJKNN_00714 8e-165 S Glutamine amidotransferase domain
DFGLJKNN_00715 0.0 kup P Transport of potassium into the cell
DFGLJKNN_00716 5.9e-185 tatD L TatD related DNase
DFGLJKNN_00717 8.3e-256 xylR 5.3.1.12 G MFS/sugar transport protein
DFGLJKNN_00719 3.4e-86 K Transcriptional regulator
DFGLJKNN_00720 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DFGLJKNN_00721 1.6e-130
DFGLJKNN_00722 8.6e-59
DFGLJKNN_00723 4.6e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DFGLJKNN_00724 2.7e-126 dedA S SNARE associated Golgi protein
DFGLJKNN_00726 1.8e-133 S HAD hydrolase, family IA, variant 3
DFGLJKNN_00727 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
DFGLJKNN_00728 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
DFGLJKNN_00729 5.2e-87 hspR K transcriptional regulator, MerR family
DFGLJKNN_00730 7.1e-173 dnaJ1 O DnaJ molecular chaperone homology domain
DFGLJKNN_00731 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DFGLJKNN_00732 0.0 dnaK O Heat shock 70 kDa protein
DFGLJKNN_00733 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
DFGLJKNN_00734 2.9e-190 K Psort location Cytoplasmic, score
DFGLJKNN_00737 1.2e-131 G Phosphoglycerate mutase family
DFGLJKNN_00738 6.2e-69 S Protein of unknown function (DUF4235)
DFGLJKNN_00739 1.2e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
DFGLJKNN_00740 1.1e-45
DFGLJKNN_00741 2.8e-277 3.6.4.12 K Putative DNA-binding domain
DFGLJKNN_00742 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
DFGLJKNN_00743 4e-281 argH 4.3.2.1 E argininosuccinate lyase
DFGLJKNN_00744 6.1e-108 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
DFGLJKNN_00745 1.6e-143 S Putative ABC-transporter type IV
DFGLJKNN_00746 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DFGLJKNN_00747 3.6e-159 L Tetratricopeptide repeat
DFGLJKNN_00748 8.6e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
DFGLJKNN_00750 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DFGLJKNN_00751 3.6e-104
DFGLJKNN_00752 6.8e-116 trkA P TrkA-N domain
DFGLJKNN_00753 8.6e-236 trkB P Cation transport protein
DFGLJKNN_00754 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DFGLJKNN_00755 7.8e-292 recN L May be involved in recombinational repair of damaged DNA
DFGLJKNN_00756 8.9e-124 S Haloacid dehalogenase-like hydrolase
DFGLJKNN_00757 1.1e-57 K helix_turn_helix gluconate operon transcriptional repressor
DFGLJKNN_00758 5e-176 V ATPases associated with a variety of cellular activities
DFGLJKNN_00759 3.1e-125 S ABC-2 family transporter protein
DFGLJKNN_00760 1.2e-121 S ABC-2 family transporter protein
DFGLJKNN_00761 7.8e-285 thrC 4.2.3.1 E Threonine synthase N terminus
DFGLJKNN_00762 5.3e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DFGLJKNN_00763 1.3e-91
DFGLJKNN_00764 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DFGLJKNN_00765 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DFGLJKNN_00767 2.1e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DFGLJKNN_00768 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DFGLJKNN_00769 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DFGLJKNN_00770 3.8e-78 S Bacterial PH domain
DFGLJKNN_00771 1.2e-254 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
DFGLJKNN_00773 5.8e-108
DFGLJKNN_00774 1.9e-132 C Putative TM nitroreductase
DFGLJKNN_00775 5.7e-142 yijF S Domain of unknown function (DUF1287)
DFGLJKNN_00776 2.7e-70 pdxH S Pfam:Pyridox_oxidase
DFGLJKNN_00777 3.5e-146 KT RESPONSE REGULATOR receiver
DFGLJKNN_00778 3.7e-193 V VanZ like family
DFGLJKNN_00779 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
DFGLJKNN_00780 1.6e-97 ypjC S Putative ABC-transporter type IV
DFGLJKNN_00781 8.9e-159
DFGLJKNN_00783 1.2e-97 EGP Major facilitator Superfamily
DFGLJKNN_00784 3e-28 EGP Major facilitator Superfamily
DFGLJKNN_00785 9.8e-164 rpoC M heme binding
DFGLJKNN_00786 7.3e-80 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DFGLJKNN_00787 6.5e-125
DFGLJKNN_00788 2.1e-131 S SOS response associated peptidase (SRAP)
DFGLJKNN_00789 1.2e-182 S Acetyltransferase (GNAT) domain
DFGLJKNN_00790 2.7e-38 J Aminoacyl-tRNA editing domain
DFGLJKNN_00791 1.3e-100 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
DFGLJKNN_00792 1.1e-56 K Transcriptional regulator
DFGLJKNN_00793 2.6e-97 MA20_25245 K FR47-like protein
DFGLJKNN_00794 1.5e-120 ydaF_1 J Acetyltransferase (GNAT) domain
DFGLJKNN_00795 2.4e-62 yeaO K Protein of unknown function, DUF488
DFGLJKNN_00796 2.1e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DFGLJKNN_00797 8.8e-284 S Psort location Cytoplasmic, score 8.87
DFGLJKNN_00798 1.5e-109 S Domain of unknown function (DUF4194)
DFGLJKNN_00799 0.0 S Psort location Cytoplasmic, score 8.87
DFGLJKNN_00800 2e-299 E Serine carboxypeptidase
DFGLJKNN_00801 1e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DFGLJKNN_00802 3.7e-171 corA P CorA-like Mg2+ transporter protein
DFGLJKNN_00803 5.8e-169 ET Bacterial periplasmic substrate-binding proteins
DFGLJKNN_00804 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DFGLJKNN_00805 3.1e-84 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
DFGLJKNN_00806 0.0 comE S Competence protein
DFGLJKNN_00807 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
DFGLJKNN_00808 3.8e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
DFGLJKNN_00809 1.5e-158 yeaZ 2.3.1.234 O Glycoprotease family
DFGLJKNN_00810 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
DFGLJKNN_00811 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DFGLJKNN_00813 2.6e-169 M Peptidase family M23
DFGLJKNN_00814 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
DFGLJKNN_00815 3.2e-276 G ABC transporter substrate-binding protein
DFGLJKNN_00816 2.2e-240 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
DFGLJKNN_00817 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
DFGLJKNN_00818 5.7e-91
DFGLJKNN_00819 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
DFGLJKNN_00820 5.8e-88 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DFGLJKNN_00821 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
DFGLJKNN_00822 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DFGLJKNN_00823 1e-127 3.2.1.8 S alpha beta
DFGLJKNN_00824 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DFGLJKNN_00825 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DFGLJKNN_00826 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
DFGLJKNN_00827 2.3e-226 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DFGLJKNN_00828 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DFGLJKNN_00829 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DFGLJKNN_00830 7.1e-308 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DFGLJKNN_00831 1.7e-243 G Bacterial extracellular solute-binding protein
DFGLJKNN_00832 1.4e-173 G Binding-protein-dependent transport system inner membrane component
DFGLJKNN_00833 1e-168 G ABC transporter permease
DFGLJKNN_00834 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
DFGLJKNN_00835 6.9e-178 2.7.1.2 GK ROK family
DFGLJKNN_00836 3.2e-217 GK ROK family
DFGLJKNN_00837 3.1e-206 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
DFGLJKNN_00838 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DFGLJKNN_00839 1.4e-197 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DFGLJKNN_00840 8.9e-303 ybiT S ABC transporter
DFGLJKNN_00841 1.5e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
DFGLJKNN_00842 3.2e-235 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DFGLJKNN_00843 9.6e-118 K Transcriptional regulatory protein, C terminal
DFGLJKNN_00845 1.4e-58 V MacB-like periplasmic core domain
DFGLJKNN_00846 6.1e-77
DFGLJKNN_00847 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DFGLJKNN_00848 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DFGLJKNN_00849 7.5e-180 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
DFGLJKNN_00850 2.6e-177 rapZ S Displays ATPase and GTPase activities
DFGLJKNN_00851 6.9e-173 whiA K May be required for sporulation
DFGLJKNN_00852 2.6e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
DFGLJKNN_00853 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DFGLJKNN_00854 8e-33 secG U Preprotein translocase SecG subunit
DFGLJKNN_00855 2.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DFGLJKNN_00856 8e-162 S Sucrose-6F-phosphate phosphohydrolase
DFGLJKNN_00857 7e-240 mepA_6 V MatE
DFGLJKNN_00858 2.2e-252 brnQ U Component of the transport system for branched-chain amino acids
DFGLJKNN_00859 1.2e-143 yoaK S Protein of unknown function (DUF1275)
DFGLJKNN_00860 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DFGLJKNN_00861 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
DFGLJKNN_00862 4.1e-218 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DFGLJKNN_00863 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DFGLJKNN_00864 7.1e-160 G Fructosamine kinase
DFGLJKNN_00865 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DFGLJKNN_00866 3.7e-156 S PAC2 family
DFGLJKNN_00870 6.1e-272
DFGLJKNN_00873 1.7e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DFGLJKNN_00874 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DFGLJKNN_00875 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
DFGLJKNN_00876 1e-131 yebC K transcriptional regulatory protein
DFGLJKNN_00877 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DFGLJKNN_00879 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DFGLJKNN_00880 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DFGLJKNN_00881 2.6e-44 yajC U Preprotein translocase subunit
DFGLJKNN_00882 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DFGLJKNN_00883 1.1e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DFGLJKNN_00884 2.4e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DFGLJKNN_00885 1.1e-245
DFGLJKNN_00886 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DFGLJKNN_00887 5.7e-30
DFGLJKNN_00888 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DFGLJKNN_00889 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DFGLJKNN_00890 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
DFGLJKNN_00891 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DFGLJKNN_00892 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DFGLJKNN_00893 6.7e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DFGLJKNN_00894 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
DFGLJKNN_00895 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
DFGLJKNN_00896 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
DFGLJKNN_00897 1.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DFGLJKNN_00898 4e-173 S Bacterial protein of unknown function (DUF881)
DFGLJKNN_00899 2.6e-31 sbp S Protein of unknown function (DUF1290)
DFGLJKNN_00900 1.2e-141 S Bacterial protein of unknown function (DUF881)
DFGLJKNN_00901 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
DFGLJKNN_00902 2.7e-120 K helix_turn_helix, mercury resistance
DFGLJKNN_00903 7.3e-62
DFGLJKNN_00905 3.3e-24 L DNA integration
DFGLJKNN_00906 2.7e-125 S GyrI-like small molecule binding domain
DFGLJKNN_00907 3.6e-90 K Putative zinc ribbon domain
DFGLJKNN_00909 6.2e-142 pgp 3.1.3.18 S HAD-hyrolase-like
DFGLJKNN_00910 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
DFGLJKNN_00911 0.0 helY L DEAD DEAH box helicase
DFGLJKNN_00912 1e-51
DFGLJKNN_00913 0.0 pafB K WYL domain
DFGLJKNN_00914 7.4e-288 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
DFGLJKNN_00916 1.3e-90 dkgB S Oxidoreductase, aldo keto reductase family protein
DFGLJKNN_00917 4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
DFGLJKNN_00918 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DFGLJKNN_00919 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DFGLJKNN_00920 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
DFGLJKNN_00921 9.6e-86 T Domain of unknown function (DUF4234)
DFGLJKNN_00922 1.9e-101 K Bacterial regulatory proteins, tetR family
DFGLJKNN_00923 4.2e-19
DFGLJKNN_00924 3.1e-49 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
DFGLJKNN_00925 3.7e-41 K Helix-turn-helix
DFGLJKNN_00926 2.2e-223 hipA 2.7.11.1 S HipA N-terminal domain
DFGLJKNN_00927 2.7e-69 4.1.1.44 S Cupin domain
DFGLJKNN_00928 2.3e-176 S Membrane transport protein
DFGLJKNN_00929 1e-93 laaE K Transcriptional regulator PadR-like family
DFGLJKNN_00930 2.3e-133 magIII L endonuclease III
DFGLJKNN_00931 3.3e-132 S Enoyl-(Acyl carrier protein) reductase
DFGLJKNN_00932 4.4e-242 vbsD V MatE
DFGLJKNN_00933 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DFGLJKNN_00935 4.8e-133
DFGLJKNN_00936 4.7e-196 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
DFGLJKNN_00937 1e-16 K MerR family regulatory protein
DFGLJKNN_00938 1.1e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DFGLJKNN_00939 7.4e-180 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DFGLJKNN_00940 7.7e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
DFGLJKNN_00941 6.8e-181 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
DFGLJKNN_00942 1.2e-279 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DFGLJKNN_00943 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
DFGLJKNN_00944 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DFGLJKNN_00945 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
DFGLJKNN_00947 3.1e-161 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
DFGLJKNN_00948 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DFGLJKNN_00949 1.2e-100 sixA T Phosphoglycerate mutase family
DFGLJKNN_00950 2.2e-207 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DFGLJKNN_00951 8.8e-178 I alpha/beta hydrolase fold
DFGLJKNN_00952 1.4e-23 rarD S EamA-like transporter family
DFGLJKNN_00953 3.2e-92 rarD 3.4.17.13 E Rard protein
DFGLJKNN_00954 2.5e-29
DFGLJKNN_00955 9.7e-191 mcrB L Restriction endonuclease
DFGLJKNN_00957 2.1e-144
DFGLJKNN_00958 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
DFGLJKNN_00959 0.0 thiN 2.7.6.2 H PglZ domain
DFGLJKNN_00960 2.2e-253 lexA 3.6.4.12 K Putative DNA-binding domain
DFGLJKNN_00961 1.5e-271
DFGLJKNN_00962 0.0 LV DNA restriction-modification system
DFGLJKNN_00963 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
DFGLJKNN_00964 4.6e-126 S Domain of unknown function (DUF1788)
DFGLJKNN_00965 7.4e-111 S Putative inner membrane protein (DUF1819)
DFGLJKNN_00966 2.6e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DFGLJKNN_00967 1e-110 S Sel1-like repeats.
DFGLJKNN_00968 1.4e-156 ybeM S Carbon-nitrogen hydrolase
DFGLJKNN_00969 8.9e-164 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
DFGLJKNN_00970 1.1e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
DFGLJKNN_00971 3.6e-82
DFGLJKNN_00972 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DFGLJKNN_00973 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
DFGLJKNN_00974 0.0 tetP J Elongation factor G, domain IV
DFGLJKNN_00975 4.5e-291 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
DFGLJKNN_00976 4e-13 S Membrane
DFGLJKNN_00977 3e-246 hemN H Involved in the biosynthesis of porphyrin-containing compound
DFGLJKNN_00978 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DFGLJKNN_00979 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
DFGLJKNN_00980 1.2e-135 S UPF0126 domain
DFGLJKNN_00981 2.7e-99 3.1.4.37 T RNA ligase
DFGLJKNN_00982 4e-46 S phosphoesterase or phosphohydrolase
DFGLJKNN_00983 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
DFGLJKNN_00984 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DFGLJKNN_00985 3.1e-189 S alpha beta
DFGLJKNN_00986 6.7e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DFGLJKNN_00987 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
DFGLJKNN_00988 1.6e-200 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
DFGLJKNN_00989 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DFGLJKNN_00990 9.6e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DFGLJKNN_00991 1.6e-250 corC S CBS domain
DFGLJKNN_00992 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DFGLJKNN_00993 2.2e-196 phoH T PhoH-like protein
DFGLJKNN_00994 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
DFGLJKNN_00995 6.1e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DFGLJKNN_00997 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
DFGLJKNN_00998 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DFGLJKNN_00999 1e-107 yitW S Iron-sulfur cluster assembly protein
DFGLJKNN_01000 1.5e-100 iscU C SUF system FeS assembly protein, NifU family
DFGLJKNN_01001 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DFGLJKNN_01002 1.4e-144 sufC O FeS assembly ATPase SufC
DFGLJKNN_01003 5.7e-233 sufD O FeS assembly protein SufD
DFGLJKNN_01004 4.8e-290 sufB O FeS assembly protein SufB
DFGLJKNN_01005 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DFGLJKNN_01006 2.6e-07 3.4.22.70 M Sortase family
DFGLJKNN_01007 1.7e-120 K helix_turn_helix, Lux Regulon
DFGLJKNN_01008 1.9e-75
DFGLJKNN_01009 5.9e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
DFGLJKNN_01010 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DFGLJKNN_01011 1.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DFGLJKNN_01012 1.3e-47 3.4.23.43 S Type IV leader peptidase family
DFGLJKNN_01013 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DFGLJKNN_01014 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DFGLJKNN_01015 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DFGLJKNN_01016 1.1e-36
DFGLJKNN_01017 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
DFGLJKNN_01018 9.8e-136 pgm3 G Phosphoglycerate mutase family
DFGLJKNN_01019 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
DFGLJKNN_01020 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DFGLJKNN_01021 1.9e-128 lolD V ABC transporter
DFGLJKNN_01022 5.5e-212 V FtsX-like permease family
DFGLJKNN_01023 8.2e-64 S Domain of unknown function (DUF4418)
DFGLJKNN_01024 0.0 pcrA 3.6.4.12 L DNA helicase
DFGLJKNN_01025 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
DFGLJKNN_01026 8.7e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DFGLJKNN_01027 1.8e-240 pbuX F Permease family
DFGLJKNN_01029 8.1e-47 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DFGLJKNN_01030 8.3e-108 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DFGLJKNN_01032 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
DFGLJKNN_01033 9e-40
DFGLJKNN_01034 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
DFGLJKNN_01035 1.7e-181 tnp7109-21 L Integrase core domain
DFGLJKNN_01036 8.6e-48 L Transposase
DFGLJKNN_01037 1.2e-64 D MobA/MobL family
DFGLJKNN_01038 4.8e-97
DFGLJKNN_01040 3.4e-26
DFGLJKNN_01041 1.7e-83
DFGLJKNN_01042 1.5e-149 S Virulence factor BrkB
DFGLJKNN_01043 7.6e-100 bcp 1.11.1.15 O Redoxin
DFGLJKNN_01044 1.7e-38 E ABC transporter
DFGLJKNN_01045 1.1e-115 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DFGLJKNN_01046 4.3e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DFGLJKNN_01047 0.0 V FtsX-like permease family
DFGLJKNN_01048 2.6e-129 V ABC transporter
DFGLJKNN_01049 2.4e-101 K Transcriptional regulator C-terminal region
DFGLJKNN_01050 1.5e-275 aroP E aromatic amino acid transport protein AroP K03293
DFGLJKNN_01051 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DFGLJKNN_01053 8.8e-184 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
DFGLJKNN_01054 2.4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DFGLJKNN_01055 3.1e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DFGLJKNN_01056 6.1e-252 yhjE EGP Sugar (and other) transporter
DFGLJKNN_01057 1.6e-297 scrT G Transporter major facilitator family protein
DFGLJKNN_01058 4.8e-78 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
DFGLJKNN_01059 5.4e-192 K helix_turn _helix lactose operon repressor
DFGLJKNN_01060 1.1e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DFGLJKNN_01061 1.5e-164 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DFGLJKNN_01062 3.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DFGLJKNN_01063 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
DFGLJKNN_01064 3.1e-245 3.5.1.104 G Polysaccharide deacetylase
DFGLJKNN_01065 4.9e-57 K Cro/C1-type HTH DNA-binding domain
DFGLJKNN_01066 2e-12 E IrrE N-terminal-like domain
DFGLJKNN_01067 3.9e-50 E IrrE N-terminal-like domain
DFGLJKNN_01068 6.8e-65
DFGLJKNN_01069 1.9e-61
DFGLJKNN_01071 2.3e-127 S Domain of unknown function (DUF4417)
DFGLJKNN_01072 1.9e-42 S Bacterial mobilisation protein (MobC)
DFGLJKNN_01073 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DFGLJKNN_01075 1.6e-171 htpX O Belongs to the peptidase M48B family
DFGLJKNN_01076 5e-273 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
DFGLJKNN_01077 0.0 cadA P E1-E2 ATPase
DFGLJKNN_01078 4.7e-242 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
DFGLJKNN_01079 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DFGLJKNN_01081 4.1e-86 yjcF Q Acetyltransferase (GNAT) domain
DFGLJKNN_01082 4.5e-157 I Serine aminopeptidase, S33
DFGLJKNN_01083 9.3e-53 ybjQ S Putative heavy-metal-binding
DFGLJKNN_01084 8.8e-39 D DivIVA domain protein
DFGLJKNN_01085 1.7e-90 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
DFGLJKNN_01086 9.6e-172 KL Domain of unknown function (DUF3427)
DFGLJKNN_01087 0.0 KL Domain of unknown function (DUF3427)
DFGLJKNN_01088 1.4e-184 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DFGLJKNN_01090 3.2e-101
DFGLJKNN_01091 8.2e-158 yicL EG EamA-like transporter family
DFGLJKNN_01092 6e-207 pldB 3.1.1.5 I Serine aminopeptidase, S33
DFGLJKNN_01093 0.0 pip S YhgE Pip domain protein
DFGLJKNN_01094 0.0 pip S YhgE Pip domain protein
DFGLJKNN_01095 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
DFGLJKNN_01096 1e-130 fhaA T Protein of unknown function (DUF2662)
DFGLJKNN_01097 3.8e-86 fhaB T Inner membrane component of T3SS, cytoplasmic domain
DFGLJKNN_01098 8.1e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
DFGLJKNN_01099 3.1e-265 rodA D Belongs to the SEDS family
DFGLJKNN_01100 3.4e-264 pbpA M penicillin-binding protein
DFGLJKNN_01101 2e-183 T Protein tyrosine kinase
DFGLJKNN_01102 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
DFGLJKNN_01103 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
DFGLJKNN_01104 3.4e-233 srtA 3.4.22.70 M Sortase family
DFGLJKNN_01105 7.9e-143 S Bacterial protein of unknown function (DUF881)
DFGLJKNN_01106 2.6e-71 crgA D Involved in cell division
DFGLJKNN_01107 1.6e-257 L ribosomal rna small subunit methyltransferase
DFGLJKNN_01108 6.4e-145 gluP 3.4.21.105 S Rhomboid family
DFGLJKNN_01109 3.4e-35
DFGLJKNN_01110 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DFGLJKNN_01111 2e-73 I Sterol carrier protein
DFGLJKNN_01112 1.1e-17 V ATPases associated with a variety of cellular activities
DFGLJKNN_01113 7.4e-45 L Transposase
DFGLJKNN_01114 3.8e-09 L IstB-like ATP binding protein
DFGLJKNN_01115 4.3e-42 tnp7109-21 L Integrase core domain
DFGLJKNN_01116 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
DFGLJKNN_01117 4.5e-12
DFGLJKNN_01118 2.7e-118 K Bacterial regulatory proteins, tetR family
DFGLJKNN_01119 1e-216 G Transmembrane secretion effector
DFGLJKNN_01120 5.6e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DFGLJKNN_01121 1.4e-102
DFGLJKNN_01122 6.1e-45 3.6.1.13 L NUDIX domain
DFGLJKNN_01123 1.8e-228 glf 5.4.99.9 M UDP-galactopyranose mutase
DFGLJKNN_01124 2e-203 L Transposase, Mutator family
DFGLJKNN_01125 3e-155 bglA 3.2.1.21 G Glycosyl hydrolase family 1
DFGLJKNN_01126 9.5e-45 L Transposase DDE domain
DFGLJKNN_01128 3.3e-09
DFGLJKNN_01129 2.6e-43 L Transposase
DFGLJKNN_01130 7.3e-119 tnp7109-21 L Integrase core domain
DFGLJKNN_01131 7.9e-153 K Transposase IS116 IS110 IS902
DFGLJKNN_01132 4.4e-15 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DFGLJKNN_01133 8.4e-216 1.1.1.22 M UDP binding domain
DFGLJKNN_01134 0.0 wbbM M Glycosyl transferase family 8
DFGLJKNN_01135 2.5e-139 rgpC U Transport permease protein
DFGLJKNN_01136 1.8e-240 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
DFGLJKNN_01137 0.0 2.1.1.72, 3.1.4.46, 3.2.1.1 GH13 M hydrolase, family 25
DFGLJKNN_01138 2.1e-120 L Protein of unknown function (DUF1524)
DFGLJKNN_01139 1.6e-142 M Putative cell wall binding repeat 2
DFGLJKNN_01140 1.7e-253 L Transposase
DFGLJKNN_01141 9.8e-127 L IstB-like ATP binding protein
DFGLJKNN_01142 0.0 M Belongs to the glycosyl hydrolase 43 family
DFGLJKNN_01143 2.6e-174 ppm1 GT2 M Glycosyl transferase, family 2
DFGLJKNN_01144 0.0 wbbM M Glycosyl transferase family 8
DFGLJKNN_01145 4.3e-298
DFGLJKNN_01146 1.3e-207 S Acyltransferase family
DFGLJKNN_01147 2.8e-72 L Transposase
DFGLJKNN_01148 2.7e-138 tnp7109-2 L Transposase, Mutator family
DFGLJKNN_01149 1.8e-116 L Transposase
DFGLJKNN_01150 2.5e-167 rfbJ M Glycosyl transferase family 2
DFGLJKNN_01151 3.2e-310 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
DFGLJKNN_01152 9.3e-30 I transferase activity, transferring acyl groups other than amino-acyl groups
DFGLJKNN_01153 5.1e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DFGLJKNN_01154 2.7e-111 T protein histidine kinase activity
DFGLJKNN_01155 1.9e-89 K LytTr DNA-binding domain
DFGLJKNN_01156 1e-47 S Protein of unknown function (DUF3073)
DFGLJKNN_01157 1.9e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DFGLJKNN_01158 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DFGLJKNN_01159 5.2e-17 S Amidohydrolase family
DFGLJKNN_01160 7e-155 S Amidohydrolase family
DFGLJKNN_01161 0.0 yjjP S Threonine/Serine exporter, ThrE
DFGLJKNN_01162 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DFGLJKNN_01163 7.3e-239 yhjX EGP Major facilitator Superfamily
DFGLJKNN_01164 6.1e-307 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DFGLJKNN_01165 0.0 trxB1 1.8.1.9 C Thioredoxin domain
DFGLJKNN_01166 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
DFGLJKNN_01167 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
DFGLJKNN_01168 1.9e-95 K helix_turn _helix lactose operon repressor
DFGLJKNN_01169 1.2e-241 ytfL P Transporter associated domain
DFGLJKNN_01170 4.1e-187 yddG EG EamA-like transporter family
DFGLJKNN_01171 3.3e-83 dps P Belongs to the Dps family
DFGLJKNN_01172 3.3e-135 S Protein of unknown function DUF45
DFGLJKNN_01173 3.6e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
DFGLJKNN_01174 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
DFGLJKNN_01175 8.6e-78 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DFGLJKNN_01176 2.2e-188 K helix_turn _helix lactose operon repressor
DFGLJKNN_01177 0.0 G Glycosyl hydrolase family 20, domain 2
DFGLJKNN_01180 0.0 3.2.1.55 GH51 G arabinose metabolic process
DFGLJKNN_01181 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DFGLJKNN_01182 2.5e-124 gntR K FCD
DFGLJKNN_01183 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DFGLJKNN_01185 8.3e-09 K helix_turn _helix lactose operon repressor
DFGLJKNN_01186 1.2e-227 I Serine aminopeptidase, S33
DFGLJKNN_01187 5.5e-188 K Periplasmic binding protein domain
DFGLJKNN_01188 4.6e-187 G Glycosyl hydrolases family 43
DFGLJKNN_01189 1.2e-06 S Parallel beta-helix repeats
DFGLJKNN_01190 6.5e-14 abfA1 3.2.1.55 GH51 G arabinose metabolic process
DFGLJKNN_01191 6.7e-72 S Transmembrane domain of unknown function (DUF3566)
DFGLJKNN_01192 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DFGLJKNN_01193 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DFGLJKNN_01194 2e-87 S Protein of unknown function (DUF721)
DFGLJKNN_01195 1.3e-238 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DFGLJKNN_01196 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DFGLJKNN_01197 1.3e-277 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DFGLJKNN_01198 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DFGLJKNN_01199 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
DFGLJKNN_01200 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
DFGLJKNN_01201 1.3e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DFGLJKNN_01202 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
DFGLJKNN_01203 2.6e-242 parB K Belongs to the ParB family
DFGLJKNN_01204 2.6e-203 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DFGLJKNN_01205 0.0 murJ KLT MviN-like protein
DFGLJKNN_01206 0.0 M Conserved repeat domain
DFGLJKNN_01207 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
DFGLJKNN_01208 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
DFGLJKNN_01209 6.7e-113 S LytR cell envelope-related transcriptional attenuator
DFGLJKNN_01210 6e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DFGLJKNN_01211 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DFGLJKNN_01212 1.2e-211 S G5
DFGLJKNN_01214 3.3e-151 O Thioredoxin
DFGLJKNN_01215 0.0 KLT Protein tyrosine kinase
DFGLJKNN_01216 3.4e-174 K Psort location Cytoplasmic, score
DFGLJKNN_01217 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
DFGLJKNN_01218 9.5e-103 L Helix-turn-helix domain
DFGLJKNN_01219 0.0 S LPXTG-motif cell wall anchor domain protein
DFGLJKNN_01220 1.9e-244 M LPXTG-motif cell wall anchor domain protein
DFGLJKNN_01221 1.3e-179 3.4.22.70 M Sortase family
DFGLJKNN_01222 1.2e-144
DFGLJKNN_01223 2e-269 KLT Domain of unknown function (DUF4032)
DFGLJKNN_01224 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DFGLJKNN_01226 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
DFGLJKNN_01227 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
DFGLJKNN_01228 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
DFGLJKNN_01229 0.0 yjcE P Sodium/hydrogen exchanger family
DFGLJKNN_01230 1.2e-145 ypfH S Phospholipase/Carboxylesterase
DFGLJKNN_01231 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DFGLJKNN_01232 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
DFGLJKNN_01233 4e-144 cobB2 K Sir2 family
DFGLJKNN_01234 1.9e-233
DFGLJKNN_01235 5.3e-306 EGP Major facilitator Superfamily
DFGLJKNN_01236 2.5e-226 mntH P H( )-stimulated, divalent metal cation uptake system
DFGLJKNN_01237 2.1e-134 L Protein of unknown function (DUF1524)
DFGLJKNN_01238 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
DFGLJKNN_01239 9.3e-11 3.2.1.14 GH18 EM Domain of unknown function (DUF5011)
DFGLJKNN_01240 7.2e-201 K helix_turn _helix lactose operon repressor
DFGLJKNN_01241 2.5e-103 G Glycosyl hydrolases family 43
DFGLJKNN_01242 2.2e-174 G Glycosyl hydrolases family 43
DFGLJKNN_01245 1.1e-110 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DFGLJKNN_01246 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DFGLJKNN_01247 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DFGLJKNN_01248 3.9e-201 K helix_turn _helix lactose operon repressor
DFGLJKNN_01249 7.2e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DFGLJKNN_01250 4.4e-157 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DFGLJKNN_01251 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DFGLJKNN_01252 1.5e-96 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
DFGLJKNN_01253 1.4e-30 K Putative sugar-binding domain
DFGLJKNN_01254 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
DFGLJKNN_01255 5.5e-270 abcT3 P ATPases associated with a variety of cellular activities
DFGLJKNN_01256 2.4e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
DFGLJKNN_01257 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
DFGLJKNN_01258 3e-120 mgtC S MgtC family
DFGLJKNN_01260 6.9e-201
DFGLJKNN_01262 1.5e-190
DFGLJKNN_01263 0.0 pgi 5.3.1.9 G Belongs to the GPI family
DFGLJKNN_01266 2.4e-176 S Auxin Efflux Carrier
DFGLJKNN_01267 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DFGLJKNN_01268 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DFGLJKNN_01269 4.4e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DFGLJKNN_01271 7.6e-92 ilvN 2.2.1.6 E ACT domain
DFGLJKNN_01272 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
DFGLJKNN_01273 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DFGLJKNN_01274 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DFGLJKNN_01275 1e-113 yceD S Uncharacterized ACR, COG1399
DFGLJKNN_01276 9.1e-103
DFGLJKNN_01277 2.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DFGLJKNN_01278 2e-58 S Protein of unknown function (DUF3039)
DFGLJKNN_01279 0.0 yjjK S ABC transporter
DFGLJKNN_01280 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
DFGLJKNN_01281 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
DFGLJKNN_01282 3.5e-163 P Cation efflux family
DFGLJKNN_01283 3.5e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DFGLJKNN_01284 6.3e-221 S Endonuclease/Exonuclease/phosphatase family
DFGLJKNN_01285 1.3e-93 argO S LysE type translocator
DFGLJKNN_01286 1.9e-294 ydfD EK Alanine-glyoxylate amino-transferase
DFGLJKNN_01287 6.5e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DFGLJKNN_01288 1.8e-34 CP_0960 S Belongs to the UPF0109 family
DFGLJKNN_01289 6.4e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DFGLJKNN_01290 1.9e-162 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DFGLJKNN_01291 8.9e-83 hsp20 O Hsp20/alpha crystallin family
DFGLJKNN_01292 2.9e-105 XK27_02070 S Nitroreductase family
DFGLJKNN_01293 5.8e-121 rsmD 2.1.1.171 L Conserved hypothetical protein 95
DFGLJKNN_01294 1.3e-248 U Sodium:dicarboxylate symporter family
DFGLJKNN_01295 1.1e-307
DFGLJKNN_01298 1.8e-216 steT E amino acid
DFGLJKNN_01299 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
DFGLJKNN_01300 1.4e-29 rpmB J Ribosomal L28 family
DFGLJKNN_01301 8.5e-201 yegV G pfkB family carbohydrate kinase
DFGLJKNN_01303 9.5e-242 yxiO S Vacuole effluxer Atg22 like
DFGLJKNN_01304 1.7e-131 K helix_turn_helix, mercury resistance
DFGLJKNN_01305 2.6e-17 T Toxic component of a toxin-antitoxin (TA) module
DFGLJKNN_01306 3.7e-54 relB L RelB antitoxin
DFGLJKNN_01307 4.5e-225 K Helix-turn-helix XRE-family like proteins
DFGLJKNN_01308 1.3e-12 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
DFGLJKNN_01313 2.5e-33
DFGLJKNN_01314 3.5e-07 S Scramblase
DFGLJKNN_01315 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DFGLJKNN_01316 6.7e-41 K Transcriptional regulator
DFGLJKNN_01318 7.7e-42
DFGLJKNN_01319 5.2e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
DFGLJKNN_01320 5.5e-239 MA20_36090 S Psort location Cytoplasmic, score 8.87
DFGLJKNN_01321 3.8e-119 K Bacterial regulatory proteins, tetR family
DFGLJKNN_01322 1.6e-132 M Mechanosensitive ion channel
DFGLJKNN_01323 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DFGLJKNN_01324 1.9e-30 2.1.1.72 S Protein conserved in bacteria
DFGLJKNN_01325 1.2e-154 fahA Q Fumarylacetoacetate (FAA) hydrolase family
DFGLJKNN_01326 2.5e-80 S Domain of unknown function (DUF4854)
DFGLJKNN_01327 1.1e-212 3.4.22.70 M Sortase family
DFGLJKNN_01328 4.9e-277 M LPXTG cell wall anchor motif
DFGLJKNN_01329 0.0 inlJ M domain protein
DFGLJKNN_01330 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
DFGLJKNN_01331 5.1e-145 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DFGLJKNN_01332 2.3e-184 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
DFGLJKNN_01333 1e-129 M Protein of unknown function (DUF3152)
DFGLJKNN_01334 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
DFGLJKNN_01336 8.1e-59 E Domain of unknown function (DUF5011)
DFGLJKNN_01337 5.4e-36 S Parallel beta-helix repeats
DFGLJKNN_01338 1.9e-69 rplI J Binds to the 23S rRNA
DFGLJKNN_01339 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DFGLJKNN_01340 1.1e-79 ssb1 L Single-stranded DNA-binding protein
DFGLJKNN_01341 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
DFGLJKNN_01342 1.8e-168 T Pfam Adenylate and Guanylate cyclase catalytic domain
DFGLJKNN_01343 2.4e-114
DFGLJKNN_01344 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DFGLJKNN_01345 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DFGLJKNN_01346 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
DFGLJKNN_01347 3.1e-200 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DFGLJKNN_01348 1.4e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DFGLJKNN_01349 2.8e-177 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
DFGLJKNN_01350 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
DFGLJKNN_01351 3.5e-117 nusG K Participates in transcription elongation, termination and antitermination
DFGLJKNN_01352 7.5e-30 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DFGLJKNN_01354 1.3e-229 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
DFGLJKNN_01355 1.5e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DFGLJKNN_01356 9.1e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DFGLJKNN_01357 2.4e-214 K Psort location Cytoplasmic, score
DFGLJKNN_01358 3.1e-40 rpmA J Ribosomal L27 protein
DFGLJKNN_01359 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
DFGLJKNN_01360 0.0 rne 3.1.26.12 J Ribonuclease E/G family
DFGLJKNN_01361 1.7e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
DFGLJKNN_01362 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
DFGLJKNN_01363 3.3e-256 V Efflux ABC transporter, permease protein
DFGLJKNN_01364 4.9e-165 V ATPases associated with a variety of cellular activities
DFGLJKNN_01365 8e-58
DFGLJKNN_01366 2.1e-64
DFGLJKNN_01367 4.4e-277 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
DFGLJKNN_01368 3.5e-188 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DFGLJKNN_01369 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
DFGLJKNN_01370 1.1e-289 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
DFGLJKNN_01371 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DFGLJKNN_01372 8.2e-304 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DFGLJKNN_01373 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DFGLJKNN_01374 3.4e-180 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DFGLJKNN_01375 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
DFGLJKNN_01376 8e-265 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
DFGLJKNN_01377 7.8e-238 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
DFGLJKNN_01379 2.1e-134 IQ KR domain
DFGLJKNN_01380 1.2e-15 IQ KR domain
DFGLJKNN_01381 3.2e-64 4.2.1.68 M Enolase C-terminal domain-like
DFGLJKNN_01382 1e-16 4.2.1.68 M carboxylic acid catabolic process
DFGLJKNN_01383 1.4e-184 K Bacterial regulatory proteins, lacI family
DFGLJKNN_01385 2.8e-119 cyaA 4.6.1.1 S CYTH
DFGLJKNN_01386 1.3e-163 trxA2 O Tetratricopeptide repeat
DFGLJKNN_01387 7.9e-180
DFGLJKNN_01388 6.4e-188
DFGLJKNN_01389 1.3e-166 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
DFGLJKNN_01390 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DFGLJKNN_01391 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DFGLJKNN_01392 2.2e-128
DFGLJKNN_01393 7.3e-132 K Bacterial regulatory proteins, tetR family
DFGLJKNN_01394 3.3e-226 G Transmembrane secretion effector
DFGLJKNN_01395 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DFGLJKNN_01396 2.1e-221 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
DFGLJKNN_01397 1.5e-179 S CAAX protease self-immunity
DFGLJKNN_01399 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
DFGLJKNN_01400 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DFGLJKNN_01401 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DFGLJKNN_01402 2.8e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
DFGLJKNN_01403 3.7e-251 S Calcineurin-like phosphoesterase
DFGLJKNN_01406 1.4e-63 S Domain of unknown function (DUF4143)
DFGLJKNN_01407 3.1e-95 S Domain of unknown function (DUF4143)
DFGLJKNN_01408 6.3e-298 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DFGLJKNN_01410 3.1e-124 S HAD hydrolase, family IA, variant 3
DFGLJKNN_01411 1.7e-201 P NMT1/THI5 like
DFGLJKNN_01412 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
DFGLJKNN_01413 7.1e-143
DFGLJKNN_01414 8.1e-125 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
DFGLJKNN_01415 6.2e-263 EGP Major facilitator Superfamily
DFGLJKNN_01416 4.4e-97 S GtrA-like protein
DFGLJKNN_01417 1.3e-62 S Macrophage migration inhibitory factor (MIF)
DFGLJKNN_01418 1.4e-286 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
DFGLJKNN_01419 0.0 pepD E Peptidase family C69
DFGLJKNN_01420 1.3e-107 S Phosphatidylethanolamine-binding protein
DFGLJKNN_01421 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
DFGLJKNN_01422 0.0 lmrA2 V ABC transporter transmembrane region
DFGLJKNN_01423 0.0 lmrA1 V ABC transporter, ATP-binding protein
DFGLJKNN_01424 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
DFGLJKNN_01425 9.2e-43 S Protein of unknown function (DUF1778)
DFGLJKNN_01426 6.3e-190 1.1.1.65 C Aldo/keto reductase family
DFGLJKNN_01427 6.5e-94 M Belongs to the glycosyl hydrolase 30 family
DFGLJKNN_01428 1.3e-16 M Belongs to the glycosyl hydrolase 30 family
DFGLJKNN_01430 7e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DFGLJKNN_01431 9.8e-155 sapF E ATPases associated with a variety of cellular activities
DFGLJKNN_01432 4e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
DFGLJKNN_01433 4.9e-163 EP Binding-protein-dependent transport system inner membrane component
DFGLJKNN_01434 1.4e-170 P Binding-protein-dependent transport system inner membrane component
DFGLJKNN_01435 1.8e-309 E ABC transporter, substrate-binding protein, family 5
DFGLJKNN_01436 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DFGLJKNN_01437 4.8e-276 G Bacterial extracellular solute-binding protein
DFGLJKNN_01438 3.8e-66 G carbohydrate transport
DFGLJKNN_01439 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DFGLJKNN_01440 2e-126 G ABC transporter permease
DFGLJKNN_01441 2.9e-190 K Periplasmic binding protein domain
DFGLJKNN_01442 8.5e-20 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DFGLJKNN_01443 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
DFGLJKNN_01444 1.1e-17 L Helix-turn-helix domain
DFGLJKNN_01445 2.8e-17 S Protein of unknown function (DUF2442)
DFGLJKNN_01446 2e-16 K Helix-turn-helix domain
DFGLJKNN_01447 1e-52 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
DFGLJKNN_01448 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DFGLJKNN_01449 5e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
DFGLJKNN_01450 2.7e-274 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
DFGLJKNN_01451 1.8e-127 XK27_08050 O prohibitin homologues
DFGLJKNN_01452 1.2e-241 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
DFGLJKNN_01453 2.2e-232 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DFGLJKNN_01454 2.8e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
DFGLJKNN_01455 7.6e-217 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DFGLJKNN_01456 0.0 macB_2 V ATPases associated with a variety of cellular activities
DFGLJKNN_01457 0.0 ctpE P E1-E2 ATPase
DFGLJKNN_01458 1.9e-197 yghZ C Aldo/keto reductase family
DFGLJKNN_01459 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
DFGLJKNN_01460 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
DFGLJKNN_01461 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
DFGLJKNN_01462 3.1e-127 S Short repeat of unknown function (DUF308)
DFGLJKNN_01463 0.0 pepO 3.4.24.71 O Peptidase family M13
DFGLJKNN_01464 2.2e-104 L Single-strand binding protein family
DFGLJKNN_01465 3.2e-170
DFGLJKNN_01466 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DFGLJKNN_01468 2.5e-269 recD2 3.6.4.12 L PIF1-like helicase
DFGLJKNN_01469 1.1e-161 supH S Sucrose-6F-phosphate phosphohydrolase
DFGLJKNN_01470 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
DFGLJKNN_01471 3.1e-39 KT Transcriptional regulatory protein, C terminal
DFGLJKNN_01472 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
DFGLJKNN_01473 7.7e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DFGLJKNN_01474 8e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
DFGLJKNN_01475 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
DFGLJKNN_01476 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
DFGLJKNN_01477 1.5e-186 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DFGLJKNN_01478 4.5e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DFGLJKNN_01479 3.9e-36 rpmE J Binds the 23S rRNA
DFGLJKNN_01481 1.3e-122 K helix_turn_helix, arabinose operon control protein
DFGLJKNN_01482 2.6e-163 glcU G Sugar transport protein
DFGLJKNN_01483 1.2e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
DFGLJKNN_01484 3.5e-257 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
DFGLJKNN_01485 5.6e-108
DFGLJKNN_01486 4.8e-129 S Metallo-beta-lactamase domain protein
DFGLJKNN_01487 3.1e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
DFGLJKNN_01488 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
DFGLJKNN_01489 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
DFGLJKNN_01490 1.6e-163 EG EamA-like transporter family
DFGLJKNN_01492 4.5e-125 V FtsX-like permease family
DFGLJKNN_01493 9.1e-148 S Sulfite exporter TauE/SafE
DFGLJKNN_01495 1.9e-26 L Transposase
DFGLJKNN_01496 3.4e-216 MA20_36090 S Psort location Cytoplasmic, score 8.87
DFGLJKNN_01497 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
DFGLJKNN_01498 3.3e-50 EGP Major facilitator superfamily
DFGLJKNN_01499 1.2e-11 EGP Major facilitator superfamily
DFGLJKNN_01500 5.2e-10 K Winged helix DNA-binding domain
DFGLJKNN_01501 3.7e-179 glkA 2.7.1.2 G ROK family
DFGLJKNN_01502 3.7e-301 S ATPases associated with a variety of cellular activities
DFGLJKNN_01503 9.7e-53 EGP Major facilitator Superfamily
DFGLJKNN_01504 1.7e-159 I alpha/beta hydrolase fold
DFGLJKNN_01505 1.2e-114 S Pyridoxamine 5'-phosphate oxidase
DFGLJKNN_01507 3.9e-87 S DUF218 domain
DFGLJKNN_01509 8.4e-52 S Protein of unknown function (DUF979)
DFGLJKNN_01510 4.4e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DFGLJKNN_01512 2e-126
DFGLJKNN_01513 4.7e-48 M domain, Protein
DFGLJKNN_01514 4e-19 M domain, Protein
DFGLJKNN_01515 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
DFGLJKNN_01516 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
DFGLJKNN_01517 7.1e-172 tesB I Thioesterase-like superfamily
DFGLJKNN_01518 1.1e-76 S Protein of unknown function (DUF3180)
DFGLJKNN_01519 4.3e-291 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DFGLJKNN_01520 8.4e-162 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DFGLJKNN_01521 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
DFGLJKNN_01522 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DFGLJKNN_01523 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DFGLJKNN_01524 3.5e-213 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DFGLJKNN_01525 1e-260 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
DFGLJKNN_01526 3.3e-308
DFGLJKNN_01527 1.7e-168 natA V ATPases associated with a variety of cellular activities
DFGLJKNN_01528 1.3e-232 epsG M Glycosyl transferase family 21
DFGLJKNN_01529 4.3e-273 S AI-2E family transporter
DFGLJKNN_01530 1.9e-177 3.4.14.13 M Glycosyltransferase like family 2
DFGLJKNN_01531 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
DFGLJKNN_01534 2.6e-68 S Domain of unknown function (DUF4190)
DFGLJKNN_01535 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DFGLJKNN_01536 7e-155 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DFGLJKNN_01538 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
DFGLJKNN_01539 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DFGLJKNN_01540 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
DFGLJKNN_01541 8.9e-184 lacR K Transcriptional regulator, LacI family
DFGLJKNN_01542 5.2e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DFGLJKNN_01543 3.9e-119 K Transcriptional regulatory protein, C terminal
DFGLJKNN_01544 1.4e-100
DFGLJKNN_01545 1.5e-178 V N-Acetylmuramoyl-L-alanine amidase
DFGLJKNN_01546 7.4e-109 ytrE V ABC transporter
DFGLJKNN_01547 6.6e-172
DFGLJKNN_01549 4.7e-220 vex3 V ABC transporter permease
DFGLJKNN_01550 7.2e-212 vex1 V Efflux ABC transporter, permease protein
DFGLJKNN_01551 9.9e-112 vex2 V ABC transporter, ATP-binding protein
DFGLJKNN_01552 9.8e-49 azlD E Branched-chain amino acid transport protein (AzlD)
DFGLJKNN_01553 2.2e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
DFGLJKNN_01554 2.1e-96 ptpA 3.1.3.48 T low molecular weight
DFGLJKNN_01555 1.9e-126 folA 1.5.1.3 H dihydrofolate reductase
DFGLJKNN_01556 1.6e-173 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DFGLJKNN_01557 1e-72 attW O OsmC-like protein
DFGLJKNN_01558 1.6e-191 T Universal stress protein family
DFGLJKNN_01559 2.4e-107 M NlpC/P60 family
DFGLJKNN_01560 1.4e-179 usp 3.5.1.28 CBM50 S CHAP domain
DFGLJKNN_01561 4.2e-214 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DFGLJKNN_01562 2.6e-39
DFGLJKNN_01563 1.6e-217 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DFGLJKNN_01564 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
DFGLJKNN_01565 2.3e-09 EGP Major facilitator Superfamily
DFGLJKNN_01566 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DFGLJKNN_01567 9.5e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
DFGLJKNN_01568 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DFGLJKNN_01570 4.3e-217 araJ EGP Major facilitator Superfamily
DFGLJKNN_01571 0.0 S Domain of unknown function (DUF4037)
DFGLJKNN_01572 1.5e-112 S Protein of unknown function (DUF4125)
DFGLJKNN_01573 1.1e-122
DFGLJKNN_01574 1.4e-285 pspC KT PspC domain
DFGLJKNN_01575 3.3e-264 tcsS3 KT PspC domain
DFGLJKNN_01576 3.2e-125 degU K helix_turn_helix, Lux Regulon
DFGLJKNN_01577 4.5e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DFGLJKNN_01578 6.6e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
DFGLJKNN_01579 1.4e-184 opcA G Glucose-6-phosphate dehydrogenase subunit
DFGLJKNN_01580 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DFGLJKNN_01581 1.7e-93
DFGLJKNN_01583 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
DFGLJKNN_01585 3e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DFGLJKNN_01586 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
DFGLJKNN_01587 6.7e-212 I Diacylglycerol kinase catalytic domain
DFGLJKNN_01588 1.3e-151 arbG K CAT RNA binding domain
DFGLJKNN_01589 0.0 crr G pts system, glucose-specific IIABC component
DFGLJKNN_01590 6.8e-43 M Spy0128-like isopeptide containing domain
DFGLJKNN_01591 3.2e-44 M Spy0128-like isopeptide containing domain
DFGLJKNN_01592 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
DFGLJKNN_01593 7.5e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DFGLJKNN_01594 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
DFGLJKNN_01595 1.4e-203 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DFGLJKNN_01596 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DFGLJKNN_01598 2.3e-105
DFGLJKNN_01599 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DFGLJKNN_01600 8.5e-232 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
DFGLJKNN_01601 2.1e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DFGLJKNN_01602 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DFGLJKNN_01603 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DFGLJKNN_01604 2.8e-188 nusA K Participates in both transcription termination and antitermination
DFGLJKNN_01605 8.7e-160
DFGLJKNN_01606 6e-72 L Transposase and inactivated derivatives
DFGLJKNN_01607 1.7e-33
DFGLJKNN_01609 1.3e-153 E Transglutaminase/protease-like homologues
DFGLJKNN_01610 0.0 gcs2 S A circularly permuted ATPgrasp
DFGLJKNN_01611 8.3e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DFGLJKNN_01612 1.2e-73 S EcsC protein family
DFGLJKNN_01614 5.7e-27 L DNA integration
DFGLJKNN_01615 3.3e-26
DFGLJKNN_01616 4.8e-145 fic D Fic/DOC family
DFGLJKNN_01617 3.7e-246 L Phage integrase family
DFGLJKNN_01618 3e-07
DFGLJKNN_01619 1.1e-49 relB L RelB antitoxin
DFGLJKNN_01620 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
DFGLJKNN_01621 1.9e-208 E Belongs to the peptidase S1B family
DFGLJKNN_01622 6.9e-12
DFGLJKNN_01623 3.9e-27
DFGLJKNN_01624 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DFGLJKNN_01625 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DFGLJKNN_01626 1.4e-47 S Domain of unknown function (DUF4193)
DFGLJKNN_01627 1.4e-187 S Protein of unknown function (DUF3071)
DFGLJKNN_01628 1.3e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
DFGLJKNN_01629 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DFGLJKNN_01630 0.0 lhr L DEAD DEAH box helicase
DFGLJKNN_01631 3e-228 2.7.7.7 L Transposase and inactivated derivatives
DFGLJKNN_01632 0.0 lhr L DEAD DEAH box helicase
DFGLJKNN_01633 7.6e-43 S Protein of unknown function (DUF2975)
DFGLJKNN_01634 5.2e-278 aspA 4.3.1.1 E Fumarase C C-terminus
DFGLJKNN_01635 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DFGLJKNN_01636 6.1e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DFGLJKNN_01637 1.3e-122
DFGLJKNN_01638 2.3e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
DFGLJKNN_01639 0.0 pknL 2.7.11.1 KLT PASTA
DFGLJKNN_01640 4.6e-134 plsC2 2.3.1.51 I Phosphate acyltransferases
DFGLJKNN_01641 1.5e-109
DFGLJKNN_01642 6.7e-190 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DFGLJKNN_01643 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DFGLJKNN_01644 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DFGLJKNN_01645 1e-07
DFGLJKNN_01646 7.1e-74 recX S Modulates RecA activity
DFGLJKNN_01647 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DFGLJKNN_01648 3.7e-40 S Protein of unknown function (DUF3046)
DFGLJKNN_01649 1.6e-80 K Helix-turn-helix XRE-family like proteins
DFGLJKNN_01650 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
DFGLJKNN_01651 3.2e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DFGLJKNN_01652 0.0 ftsK D FtsK SpoIIIE family protein
DFGLJKNN_01653 2e-137 fic D Fic/DOC family
DFGLJKNN_01654 9e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DFGLJKNN_01655 1.3e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DFGLJKNN_01656 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
DFGLJKNN_01657 1.1e-167 ydeD EG EamA-like transporter family
DFGLJKNN_01658 6.6e-132 ybhL S Belongs to the BI1 family
DFGLJKNN_01659 1e-97 S Domain of unknown function (DUF5067)
DFGLJKNN_01660 2.9e-268 T Histidine kinase
DFGLJKNN_01661 4.1e-116 K helix_turn_helix, Lux Regulon
DFGLJKNN_01662 0.0 S Protein of unknown function DUF262
DFGLJKNN_01663 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DFGLJKNN_01664 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
DFGLJKNN_01665 1e-237 carA 6.3.5.5 F Belongs to the CarA family
DFGLJKNN_01666 3.2e-84 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DFGLJKNN_01667 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DFGLJKNN_01669 1e-191 EGP Transmembrane secretion effector
DFGLJKNN_01670 0.0 S Esterase-like activity of phytase
DFGLJKNN_01671 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DFGLJKNN_01672 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DFGLJKNN_01673 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DFGLJKNN_01674 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DFGLJKNN_01676 5.9e-199 ltaE 4.1.2.48 E Beta-eliminating lyase
DFGLJKNN_01677 5.4e-228 M Glycosyl transferase 4-like domain
DFGLJKNN_01678 0.0 M Parallel beta-helix repeats
DFGLJKNN_01679 4.9e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DFGLJKNN_01680 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DFGLJKNN_01681 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
DFGLJKNN_01682 3.3e-110
DFGLJKNN_01683 2.1e-93 S Protein of unknown function (DUF4230)
DFGLJKNN_01684 2.1e-151 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
DFGLJKNN_01685 7.8e-16 K DNA-binding transcription factor activity
DFGLJKNN_01686 4.7e-69 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DFGLJKNN_01687 2e-32
DFGLJKNN_01688 5.7e-302 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
DFGLJKNN_01689 3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DFGLJKNN_01690 4.4e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DFGLJKNN_01691 1.9e-239 purD 6.3.4.13 F Belongs to the GARS family
DFGLJKNN_01692 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DFGLJKNN_01693 2.7e-247 S Putative esterase
DFGLJKNN_01694 0.0 lysX S Uncharacterised conserved protein (DUF2156)
DFGLJKNN_01696 2.1e-160 P Zinc-uptake complex component A periplasmic
DFGLJKNN_01697 1.6e-137 S cobalamin synthesis protein
DFGLJKNN_01698 6.1e-48 rpmB J Ribosomal L28 family
DFGLJKNN_01699 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DFGLJKNN_01700 2e-42 rpmE2 J Ribosomal protein L31
DFGLJKNN_01701 8.2e-15 rpmJ J Ribosomal protein L36
DFGLJKNN_01702 2.3e-23 J Ribosomal L32p protein family
DFGLJKNN_01703 1.6e-202 ycgR S Predicted permease
DFGLJKNN_01704 2.6e-154 S TIGRFAM TIGR03943 family protein
DFGLJKNN_01705 9.8e-45
DFGLJKNN_01706 5.1e-74 zur P Belongs to the Fur family
DFGLJKNN_01707 5.3e-228 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DFGLJKNN_01708 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DFGLJKNN_01709 2.9e-179 adh3 C Zinc-binding dehydrogenase
DFGLJKNN_01710 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DFGLJKNN_01712 5.3e-44 S Memo-like protein
DFGLJKNN_01713 2.9e-229 K Putative ATP-dependent DNA helicase recG C-terminal
DFGLJKNN_01714 3.5e-160 K Helix-turn-helix domain, rpiR family
DFGLJKNN_01715 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DFGLJKNN_01716 2.3e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
DFGLJKNN_01717 2e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DFGLJKNN_01718 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
DFGLJKNN_01719 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DFGLJKNN_01720 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DFGLJKNN_01721 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DFGLJKNN_01722 1.8e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DFGLJKNN_01723 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
DFGLJKNN_01724 4.4e-109
DFGLJKNN_01725 7.5e-27 ssb1 L Single-strand binding protein family
DFGLJKNN_01726 6.4e-19 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DFGLJKNN_01728 1.1e-53 usp 3.5.1.28 CBM50 S CHAP domain
DFGLJKNN_01729 1e-12
DFGLJKNN_01743 4.7e-25 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
DFGLJKNN_01745 2.8e-56 M Sortase family
DFGLJKNN_01749 8e-18 D nuclear chromosome segregation
DFGLJKNN_01754 4.2e-76 mtsE S TROVE domain
DFGLJKNN_01761 5.7e-108 S Plasmid encoded RepA protein
DFGLJKNN_01763 5.7e-51 3.4.22.70 M Sortase family
DFGLJKNN_01764 1e-45 S Listeria-Bacteroides repeat domain (List_Bact_rpt)
DFGLJKNN_01766 9.6e-82 M domain protein
DFGLJKNN_01767 1.8e-101
DFGLJKNN_01771 3.3e-41
DFGLJKNN_01772 7.8e-36 L PDDEXK-like domain of unknown function (DUF3799)
DFGLJKNN_01773 1.9e-25
DFGLJKNN_01776 1.5e-88 D ftsk spoiiie
DFGLJKNN_01778 2.7e-160 D ftsk spoiiie
DFGLJKNN_01782 2.2e-24 L Transposase, IS605 OrfB family
DFGLJKNN_01783 6.6e-17
DFGLJKNN_01785 3.7e-21 flgJ S pathogenesis
DFGLJKNN_01787 2.7e-195 S AAA-like domain
DFGLJKNN_01792 3e-07
DFGLJKNN_01794 2.6e-42 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
DFGLJKNN_01797 4.6e-29 2.1.1.37 H C-5 cytosine-specific DNA methylase
DFGLJKNN_01798 4e-50 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
DFGLJKNN_01799 5.4e-46 Q methyltransferase
DFGLJKNN_01800 9.8e-20
DFGLJKNN_01806 6.9e-36 S P22_AR N-terminal domain
DFGLJKNN_01807 3.1e-36
DFGLJKNN_01808 4.5e-21 T Pentapeptide repeats (8 copies)
DFGLJKNN_01809 1.4e-07
DFGLJKNN_01811 3.2e-152 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DFGLJKNN_01812 3.1e-09
DFGLJKNN_01819 3.2e-07 D protein tyrosine kinase activity
DFGLJKNN_01822 4e-151 S COG0433 Predicted ATPase
DFGLJKNN_01825 4e-82 3.2.2.27 NU Tfp pilus assembly protein FimV
DFGLJKNN_01827 4e-25 parA D COG1192 ATPases involved in chromosome partitioning
DFGLJKNN_01829 1.7e-46
DFGLJKNN_01831 3e-51 L endonuclease I
DFGLJKNN_01835 1.9e-15
DFGLJKNN_01837 8.8e-08 E Transcription factor WhiB
DFGLJKNN_01841 5e-39 S DNA N-6-adenine-methyltransferase (Dam)
DFGLJKNN_01842 2.1e-16 L Transposase
DFGLJKNN_01845 2.5e-09
DFGLJKNN_01846 2.1e-18
DFGLJKNN_01853 3.9e-27 S Bacterial toxin of type II toxin-antitoxin system, YafQ
DFGLJKNN_01854 1.2e-31 3.1.1.53 L Calcineurin-like phosphoesterase
DFGLJKNN_01855 3.8e-08
DFGLJKNN_01857 1.1e-15 L Helix-turn-helix domain
DFGLJKNN_01860 2.8e-225 L PFAM Integrase catalytic
DFGLJKNN_01861 4.5e-35 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
DFGLJKNN_01862 2e-44 2.1.1.72 V Type I restriction modification DNA specificity domain
DFGLJKNN_01863 1.3e-295 bcgIA 2.1.1.72 V N-6 DNA Methylase
DFGLJKNN_01865 5.3e-08
DFGLJKNN_01866 1.4e-18
DFGLJKNN_01867 1e-15
DFGLJKNN_01868 2.1e-303 K RNA polymerase II activating transcription factor binding
DFGLJKNN_01869 5.5e-34 M S-layer homology domain
DFGLJKNN_01870 6.5e-08 MU Listeria-Bacteroides repeat domain (List_Bact_rpt)
DFGLJKNN_01872 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
DFGLJKNN_01873 2.9e-156 S Domain of unknown function (DUF4357)
DFGLJKNN_01874 2.4e-30
DFGLJKNN_01875 1e-178 L Phage integrase family
DFGLJKNN_01876 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DFGLJKNN_01877 1.4e-84 argR K Regulates arginine biosynthesis genes
DFGLJKNN_01878 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DFGLJKNN_01879 2.8e-246 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
DFGLJKNN_01880 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DFGLJKNN_01881 1.8e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DFGLJKNN_01882 3.8e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DFGLJKNN_01883 8.6e-87
DFGLJKNN_01884 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
DFGLJKNN_01885 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DFGLJKNN_01886 5.4e-161 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DFGLJKNN_01887 1.2e-135 ybbL V ATPases associated with a variety of cellular activities
DFGLJKNN_01888 4.2e-136 ybbM V Uncharacterised protein family (UPF0014)
DFGLJKNN_01889 6e-42 IQ oxidoreductase activity
DFGLJKNN_01891 8e-94 K AraC-like ligand binding domain
DFGLJKNN_01892 2.4e-237 rutG F Permease family
DFGLJKNN_01893 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
DFGLJKNN_01894 4.2e-63 S Phospholipase/Carboxylesterase
DFGLJKNN_01895 3.1e-187 MA20_14895 S Conserved hypothetical protein 698
DFGLJKNN_01896 7.8e-146 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
DFGLJKNN_01897 2.1e-117 3.1.3.27 E haloacid dehalogenase-like hydrolase
DFGLJKNN_01898 2.2e-290 2.4.1.166 GT2 M Glycosyltransferase like family 2
DFGLJKNN_01900 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
DFGLJKNN_01901 1.2e-125 ypfH S Phospholipase/Carboxylesterase
DFGLJKNN_01902 3.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DFGLJKNN_01903 2.1e-23
DFGLJKNN_01904 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
DFGLJKNN_01905 2.8e-66 S Zincin-like metallopeptidase
DFGLJKNN_01906 8.2e-91 S Helix-turn-helix
DFGLJKNN_01907 2.5e-199 S Short C-terminal domain
DFGLJKNN_01908 2.7e-22
DFGLJKNN_01909 2.9e-12
DFGLJKNN_01911 4.5e-79 K Psort location Cytoplasmic, score
DFGLJKNN_01912 1.9e-255 KLT Protein tyrosine kinase
DFGLJKNN_01913 3.6e-71 S Cupin 2, conserved barrel domain protein
DFGLJKNN_01914 2.8e-157 ksgA 2.1.1.182 J Methyltransferase domain
DFGLJKNN_01915 5.6e-59 yccF S Inner membrane component domain
DFGLJKNN_01916 1.2e-118 E Psort location Cytoplasmic, score 8.87
DFGLJKNN_01917 3.1e-245 XK27_00240 K Fic/DOC family
DFGLJKNN_01918 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DFGLJKNN_01919 8.9e-231 mtnE 2.6.1.83 E Aminotransferase class I and II
DFGLJKNN_01920 6.4e-93 metI P Binding-protein-dependent transport system inner membrane component
DFGLJKNN_01921 1.6e-205 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DFGLJKNN_01922 3.2e-184 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
DFGLJKNN_01923 6.5e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
DFGLJKNN_01924 1.4e-147 P NLPA lipoprotein
DFGLJKNN_01925 4.9e-168 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
DFGLJKNN_01926 9.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DFGLJKNN_01927 1.2e-263 pip 3.4.11.5 S alpha/beta hydrolase fold
DFGLJKNN_01928 0.0 tcsS2 T Histidine kinase
DFGLJKNN_01929 6.1e-132 K helix_turn_helix, Lux Regulon
DFGLJKNN_01930 0.0 phoN I PAP2 superfamily
DFGLJKNN_01931 0.0 MV MacB-like periplasmic core domain
DFGLJKNN_01932 3.5e-161 V ABC transporter, ATP-binding protein
DFGLJKNN_01933 1e-251 metY 2.5.1.49 E Aminotransferase class-V
DFGLJKNN_01934 1.6e-157 S Putative ABC-transporter type IV
DFGLJKNN_01935 7.3e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DFGLJKNN_01936 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
DFGLJKNN_01937 1.3e-57 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
DFGLJKNN_01938 5.7e-283 dprA 5.99.1.2 LU DNA recombination-mediator protein A
DFGLJKNN_01939 1.2e-293 comM O Magnesium chelatase, subunit ChlI C-terminal
DFGLJKNN_01940 2.8e-69 yraN L Belongs to the UPF0102 family
DFGLJKNN_01941 4.3e-183 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
DFGLJKNN_01942 4.4e-118 safC S O-methyltransferase
DFGLJKNN_01943 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
DFGLJKNN_01944 1.2e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DFGLJKNN_01945 1.7e-234 patB 4.4.1.8 E Aminotransferase, class I II
DFGLJKNN_01948 9.1e-245 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DFGLJKNN_01949 9.4e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DFGLJKNN_01950 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DFGLJKNN_01951 3.6e-255 clcA_2 P Voltage gated chloride channel
DFGLJKNN_01952 8.1e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DFGLJKNN_01953 2.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
DFGLJKNN_01954 4.4e-114 S Protein of unknown function (DUF3000)
DFGLJKNN_01955 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DFGLJKNN_01956 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
DFGLJKNN_01957 6.4e-40
DFGLJKNN_01958 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DFGLJKNN_01959 5e-223 S Peptidase dimerisation domain
DFGLJKNN_01960 6.3e-10 P ABC-type metal ion transport system permease component
DFGLJKNN_01961 1.6e-41 P ABC-type metal ion transport system permease component
DFGLJKNN_01962 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
DFGLJKNN_01963 3.1e-174 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DFGLJKNN_01964 6.2e-58
DFGLJKNN_01965 7.3e-123
DFGLJKNN_01966 2.9e-118
DFGLJKNN_01967 2.7e-173 S Helix-turn-helix domain
DFGLJKNN_01968 1.6e-41
DFGLJKNN_01969 7.5e-91 S Transcription factor WhiB
DFGLJKNN_01970 3.8e-114 parA D AAA domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)