ORF_ID e_value Gene_name EC_number CAZy COGs Description
NEGKCHNM_00001 1.8e-13 3.1.3.48 D nuclear chromosome segregation
NEGKCHNM_00005 1.8e-256 U Type IV secretory pathway, VirB4
NEGKCHNM_00006 1.2e-288 U TraM recognition site of TraD and TraG
NEGKCHNM_00012 4.4e-79 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
NEGKCHNM_00013 5.2e-272 V N-6 DNA Methylase
NEGKCHNM_00014 5.2e-83 pin L Resolvase, N terminal domain
NEGKCHNM_00016 9.7e-61 V Psort location Cytoplasmic, score
NEGKCHNM_00017 4.7e-38
NEGKCHNM_00019 3.1e-42
NEGKCHNM_00021 3.3e-78
NEGKCHNM_00024 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NEGKCHNM_00025 5.1e-29 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NEGKCHNM_00026 1.9e-09 L Psort location Cytoplasmic, score 8.96
NEGKCHNM_00030 1.2e-20
NEGKCHNM_00032 8.2e-198 topB 5.99.1.2 L DNA topoisomerase
NEGKCHNM_00034 1.7e-75 XK27_08505 D nucleotidyltransferase activity
NEGKCHNM_00035 9.2e-37 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
NEGKCHNM_00036 2.1e-31 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NEGKCHNM_00037 2.3e-32
NEGKCHNM_00038 0.0 traA 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NEGKCHNM_00040 4e-95
NEGKCHNM_00041 5.1e-24 S Fic/DOC family
NEGKCHNM_00042 1.3e-53 L single-stranded DNA binding
NEGKCHNM_00044 1.2e-98 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
NEGKCHNM_00045 2.8e-94 S Protein of unknown function (DUF2786)
NEGKCHNM_00048 4e-24
NEGKCHNM_00052 1.5e-143 recQ 3.6.4.12, 5.99.1.2 F RecQ zinc-binding
NEGKCHNM_00054 2e-20
NEGKCHNM_00056 1.4e-79 L helicase
NEGKCHNM_00058 1.7e-10
NEGKCHNM_00061 3.5e-11
NEGKCHNM_00069 4.4e-34
NEGKCHNM_00070 7.2e-181 L Phage integrase family
NEGKCHNM_00072 2.2e-57 S Helix-turn-helix domain
NEGKCHNM_00073 3.2e-10 S Helix-turn-helix domain
NEGKCHNM_00077 2.5e-60 ydhQ 2.7.11.1 MU cell adhesion
NEGKCHNM_00081 4.2e-189 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEGKCHNM_00082 1e-139 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEGKCHNM_00083 3.2e-101
NEGKCHNM_00084 1.6e-241 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEGKCHNM_00085 3.6e-168 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEGKCHNM_00086 2.9e-35 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEGKCHNM_00087 2.3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
NEGKCHNM_00088 4.6e-233 EGP Major facilitator Superfamily
NEGKCHNM_00089 8.6e-107 3.1.3.27 E haloacid dehalogenase-like hydrolase
NEGKCHNM_00090 9.8e-12 G Fic/DOC family
NEGKCHNM_00091 1.9e-132 G Fic/DOC family
NEGKCHNM_00092 2e-142
NEGKCHNM_00093 3.6e-158 IQ Enoyl-(Acyl carrier protein) reductase
NEGKCHNM_00094 1.4e-84 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NEGKCHNM_00095 2.4e-75 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NEGKCHNM_00096 1.2e-94 bcp 1.11.1.15 O Redoxin
NEGKCHNM_00097 1.2e-24 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_00098 2.8e-94 S Pyridoxamine 5'-phosphate oxidase
NEGKCHNM_00099 4e-206 S Histidine phosphatase superfamily (branch 2)
NEGKCHNM_00100 9.8e-144 S Histidine phosphatase superfamily (branch 2)
NEGKCHNM_00101 4.6e-44 L transposition
NEGKCHNM_00102 1.1e-23 C Acetamidase/Formamidase family
NEGKCHNM_00103 2.3e-46 K helix_turn_helix gluconate operon transcriptional repressor
NEGKCHNM_00104 2.6e-74 V ATPases associated with a variety of cellular activities
NEGKCHNM_00105 7e-68 V ATPases associated with a variety of cellular activities
NEGKCHNM_00106 1.2e-121 S ABC-2 family transporter protein
NEGKCHNM_00107 4.4e-123 S Haloacid dehalogenase-like hydrolase
NEGKCHNM_00108 6.2e-262 recN L May be involved in recombinational repair of damaged DNA
NEGKCHNM_00109 1.6e-157 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEGKCHNM_00110 5.3e-15 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEGKCHNM_00111 6.7e-63 trkB P Cation transport protein
NEGKCHNM_00112 2.8e-191 trkB P Cation transport protein
NEGKCHNM_00113 3e-116 trkA P TrkA-N domain
NEGKCHNM_00114 1.1e-133 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NEGKCHNM_00115 8.3e-131 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NEGKCHNM_00116 2e-46 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NEGKCHNM_00117 8.8e-30 L Tetratricopeptide repeat
NEGKCHNM_00118 4e-100 L Tetratricopeptide repeat
NEGKCHNM_00119 1.1e-247 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEGKCHNM_00120 0.0 S Protein of unknown function (DUF975)
NEGKCHNM_00121 1e-134 S Putative ABC-transporter type IV
NEGKCHNM_00122 3.7e-93 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NEGKCHNM_00123 2.9e-279 argH 4.3.2.1 E argininosuccinate lyase
NEGKCHNM_00124 2e-140 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEGKCHNM_00125 4e-38 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEGKCHNM_00126 8.9e-16 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEGKCHNM_00127 4.1e-47 argR K Regulates arginine biosynthesis genes
NEGKCHNM_00128 2.5e-115 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEGKCHNM_00129 7.7e-40 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEGKCHNM_00130 1e-240 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
NEGKCHNM_00131 2.8e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NEGKCHNM_00132 8.2e-205 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NEGKCHNM_00133 2e-205 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NEGKCHNM_00134 4.9e-99
NEGKCHNM_00135 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
NEGKCHNM_00136 1.5e-97 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEGKCHNM_00137 1.7e-80 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEGKCHNM_00138 1.9e-153 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEGKCHNM_00139 1.3e-93 yvdD 3.2.2.10 S Possible lysine decarboxylase
NEGKCHNM_00140 8.9e-253 glnA 6.3.1.2 E glutamine synthetase
NEGKCHNM_00141 7.2e-19 glnA 6.3.1.2 E glutamine synthetase
NEGKCHNM_00142 6e-143 S Domain of unknown function (DUF4191)
NEGKCHNM_00143 4.9e-247 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NEGKCHNM_00144 7.2e-94 S Protein of unknown function (DUF3043)
NEGKCHNM_00145 7.9e-170 argE E Peptidase dimerisation domain
NEGKCHNM_00146 2.4e-56 argE E Peptidase dimerisation domain
NEGKCHNM_00147 4.9e-129 cbiQ P Cobalt transport protein
NEGKCHNM_00148 3.1e-265 ykoD P ATPases associated with a variety of cellular activities
NEGKCHNM_00149 9.8e-73 ykoE S ABC-type cobalt transport system, permease component
NEGKCHNM_00150 1.4e-182 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NEGKCHNM_00151 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEGKCHNM_00152 0.0 S Tetratricopeptide repeat
NEGKCHNM_00153 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NEGKCHNM_00154 9.5e-278 2.8.2.22 S Arylsulfotransferase Ig-like domain
NEGKCHNM_00155 7.6e-16 2.8.2.22 S Arylsulfotransferase Ig-like domain
NEGKCHNM_00156 5e-145 bioM P ATPases associated with a variety of cellular activities
NEGKCHNM_00157 2.5e-62 E Aminotransferase class I and II
NEGKCHNM_00158 2.8e-140 E Aminotransferase class I and II
NEGKCHNM_00159 9.3e-141 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
NEGKCHNM_00160 4.9e-198 S Glycosyltransferase, group 2 family protein
NEGKCHNM_00162 6.3e-145 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NEGKCHNM_00163 2.4e-47 yhbY J CRS1_YhbY
NEGKCHNM_00164 0.0 ecfA GP ABC transporter, ATP-binding protein
NEGKCHNM_00165 3.8e-59 ecfA GP ABC transporter, ATP-binding protein
NEGKCHNM_00166 1.4e-108 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEGKCHNM_00167 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
NEGKCHNM_00169 1.7e-102 kcsA U Ion channel
NEGKCHNM_00170 1.3e-182 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NEGKCHNM_00171 5.9e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEGKCHNM_00172 1.2e-123 3.2.1.8 S alpha beta
NEGKCHNM_00174 2.5e-32 S Protein of unknown function DUF262
NEGKCHNM_00175 0.0 S Protein of unknown function DUF262
NEGKCHNM_00176 8.5e-252 S AAA-like domain
NEGKCHNM_00177 4.2e-56 S SIR2-like domain
NEGKCHNM_00178 3.9e-184 3.1.21.4 V Type III restriction enzyme res subunit
NEGKCHNM_00179 6.9e-56 L Eco57I restriction-modification methylase
NEGKCHNM_00180 1.9e-65 L Eco57I restriction-modification methylase
NEGKCHNM_00181 0.0 KL Type III restriction enzyme res subunit
NEGKCHNM_00182 2.6e-131 XK26_04895
NEGKCHNM_00183 1.6e-41 lexA 3.6.4.12 K Putative DNA-binding domain
NEGKCHNM_00184 2.2e-65 S Putative inner membrane protein (DUF1819)
NEGKCHNM_00185 3.2e-22
NEGKCHNM_00186 1.5e-69
NEGKCHNM_00187 4.3e-211
NEGKCHNM_00188 4.6e-148 S phosphoesterase or phosphohydrolase
NEGKCHNM_00189 1.4e-41 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NEGKCHNM_00190 4e-80 4.1.1.44 S Cupin domain
NEGKCHNM_00191 4.9e-141 C Aldo/keto reductase family
NEGKCHNM_00192 2.5e-127 E Psort location Cytoplasmic, score 8.87
NEGKCHNM_00193 6.3e-134 yebE S DUF218 domain
NEGKCHNM_00194 2.7e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEGKCHNM_00195 9e-110 rnd 3.1.13.5, 3.6.4.12 J 3'-5' exonuclease
NEGKCHNM_00196 3.9e-106 rnd 3.1.13.5 J 3'-5' exonuclease
NEGKCHNM_00197 9.9e-80 S Protein of unknown function (DUF3000)
NEGKCHNM_00198 7.4e-166 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEGKCHNM_00199 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
NEGKCHNM_00200 4.5e-31
NEGKCHNM_00201 6.3e-60 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NEGKCHNM_00202 9.6e-253 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NEGKCHNM_00203 3.5e-224 S Peptidase dimerisation domain
NEGKCHNM_00204 4.8e-156 S Sucrose-6F-phosphate phosphohydrolase
NEGKCHNM_00205 1.6e-146 metQ P NLPA lipoprotein
NEGKCHNM_00206 4.2e-147 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEGKCHNM_00207 5.4e-108 metI P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00208 1.1e-74
NEGKCHNM_00210 1.4e-102 V Abi-like protein
NEGKCHNM_00212 0.0 S LPXTG-motif cell wall anchor domain protein
NEGKCHNM_00213 5.1e-246 dinF V MatE
NEGKCHNM_00214 1.2e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEGKCHNM_00215 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEGKCHNM_00216 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NEGKCHNM_00217 1e-47 S Domain of unknown function (DUF4193)
NEGKCHNM_00218 7e-147 S Protein of unknown function (DUF3071)
NEGKCHNM_00219 3e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
NEGKCHNM_00220 1.6e-224 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
NEGKCHNM_00221 1.9e-246 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
NEGKCHNM_00222 2.8e-210 lhr L DEAD DEAH box helicase
NEGKCHNM_00223 1.4e-66 lhr L DEAD DEAH box helicase
NEGKCHNM_00224 0.0 lhr L DEAD DEAH box helicase
NEGKCHNM_00225 2.4e-79 S Protein of unknown function (DUF2975)
NEGKCHNM_00226 2.5e-242 T PhoQ Sensor
NEGKCHNM_00227 1.5e-222 G Major Facilitator Superfamily
NEGKCHNM_00228 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
NEGKCHNM_00229 9.7e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEGKCHNM_00230 1.1e-118
NEGKCHNM_00231 2.2e-196 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
NEGKCHNM_00232 0.0 pknL 2.7.11.1 KLT PASTA
NEGKCHNM_00233 1.5e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
NEGKCHNM_00234 1.3e-97
NEGKCHNM_00235 6.5e-193 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NEGKCHNM_00236 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEGKCHNM_00237 1.3e-154 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEGKCHNM_00238 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEGKCHNM_00239 4.7e-64 recX S Modulates RecA activity
NEGKCHNM_00240 2.3e-207 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEGKCHNM_00241 5.6e-45 S Protein of unknown function (DUF3046)
NEGKCHNM_00242 3.6e-80 K Helix-turn-helix XRE-family like proteins
NEGKCHNM_00243 1e-96 cinA 3.5.1.42 S Belongs to the CinA family
NEGKCHNM_00244 6.7e-122 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEGKCHNM_00245 6.3e-174 ftsK D FtsK SpoIIIE family protein
NEGKCHNM_00246 0.0 ftsK D FtsK SpoIIIE family protein
NEGKCHNM_00247 1.6e-191 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEGKCHNM_00248 3.3e-280 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NEGKCHNM_00249 2.3e-133 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
NEGKCHNM_00250 9.2e-173 ydeD EG EamA-like transporter family
NEGKCHNM_00251 1.7e-127 ybhL S Belongs to the BI1 family
NEGKCHNM_00252 1.4e-57 S Domain of unknown function (DUF5067)
NEGKCHNM_00253 5.7e-242 T Histidine kinase
NEGKCHNM_00254 1.8e-127 K helix_turn_helix, Lux Regulon
NEGKCHNM_00255 0.0 S Protein of unknown function DUF262
NEGKCHNM_00256 9e-116 K helix_turn_helix, Lux Regulon
NEGKCHNM_00257 2.2e-239 T Histidine kinase
NEGKCHNM_00258 1.3e-190 V ATPases associated with a variety of cellular activities
NEGKCHNM_00259 1.7e-224 V ABC-2 family transporter protein
NEGKCHNM_00260 1.1e-229 V ABC-2 family transporter protein
NEGKCHNM_00261 6e-190 rhaR1 K helix_turn_helix, arabinose operon control protein
NEGKCHNM_00262 1.8e-108 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
NEGKCHNM_00263 9.2e-248 VP1224 V Psort location CytoplasmicMembrane, score 9.99
NEGKCHNM_00264 4.4e-216 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NEGKCHNM_00265 1.2e-272 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NEGKCHNM_00266 0.0 ctpE P E1-E2 ATPase
NEGKCHNM_00267 2e-74
NEGKCHNM_00268 1e-240 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEGKCHNM_00269 1.3e-131 S Protein of unknown function (DUF3159)
NEGKCHNM_00270 1.5e-147 S Protein of unknown function (DUF3710)
NEGKCHNM_00271 2.1e-156 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
NEGKCHNM_00272 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
NEGKCHNM_00273 6.4e-163 dppC EP N-terminal TM domain of oligopeptide transport permease C
NEGKCHNM_00274 1.5e-136 dppB EP Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00275 2.3e-311 E ABC transporter, substrate-binding protein, family 5
NEGKCHNM_00276 2.2e-168 xerC D Belongs to the 'phage' integrase family. XerC subfamily
NEGKCHNM_00277 5.2e-08
NEGKCHNM_00278 2.8e-34
NEGKCHNM_00279 7.6e-194 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
NEGKCHNM_00280 8e-148 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
NEGKCHNM_00281 5.8e-28 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
NEGKCHNM_00282 5.7e-103
NEGKCHNM_00283 0.0 typA T Elongation factor G C-terminus
NEGKCHNM_00284 1.5e-149 naiP U Sugar (and other) transporter
NEGKCHNM_00285 6.3e-83 naiP U Sugar (and other) transporter
NEGKCHNM_00286 2.6e-140 nrtR 3.6.1.55 F NUDIX hydrolase
NEGKCHNM_00287 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
NEGKCHNM_00288 5.9e-177 xerD D recombinase XerD
NEGKCHNM_00289 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEGKCHNM_00290 2.1e-25 rpmI J Ribosomal protein L35
NEGKCHNM_00291 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEGKCHNM_00292 3.4e-111 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
NEGKCHNM_00293 4.2e-83 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEGKCHNM_00294 6.7e-21 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEGKCHNM_00295 2e-58 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEGKCHNM_00296 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEGKCHNM_00297 7.9e-172 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NEGKCHNM_00298 1.8e-186 galM 5.1.3.3 G Aldose 1-epimerase
NEGKCHNM_00299 4.1e-37
NEGKCHNM_00300 7.4e-98 sigH K Belongs to the sigma-70 factor family. ECF subfamily
NEGKCHNM_00301 5.3e-276 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEGKCHNM_00302 3.5e-188 V Acetyltransferase (GNAT) domain
NEGKCHNM_00303 3.7e-288 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
NEGKCHNM_00304 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
NEGKCHNM_00305 1.5e-94 3.6.1.55 F NUDIX domain
NEGKCHNM_00306 0.0 P Belongs to the ABC transporter superfamily
NEGKCHNM_00307 1.6e-73 dppC EP Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00308 2.7e-105 dppC EP Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00309 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00310 4.7e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
NEGKCHNM_00311 1.9e-217 GK ROK family
NEGKCHNM_00312 2.9e-165 2.7.1.4 G pfkB family carbohydrate kinase
NEGKCHNM_00313 9.6e-199 S Metal-independent alpha-mannosidase (GH125)
NEGKCHNM_00314 1.9e-28
NEGKCHNM_00315 5.4e-247 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
NEGKCHNM_00316 4.6e-141 ftsQ 6.3.2.4 D Cell division protein FtsQ
NEGKCHNM_00317 5.4e-58 murC 6.3.2.8 M Belongs to the MurCDEF family
NEGKCHNM_00318 1.6e-201 murC 6.3.2.8 M Belongs to the MurCDEF family
NEGKCHNM_00319 6.4e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEGKCHNM_00320 8.1e-203 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
NEGKCHNM_00321 7.3e-256 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEGKCHNM_00322 1.5e-192 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEGKCHNM_00323 2e-200 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEGKCHNM_00324 2.3e-46 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEGKCHNM_00325 4.2e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEGKCHNM_00326 3.1e-116 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
NEGKCHNM_00327 1.4e-188 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
NEGKCHNM_00328 1.8e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NEGKCHNM_00329 8.6e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEGKCHNM_00330 7e-92 mraZ K Belongs to the MraZ family
NEGKCHNM_00331 0.0 L DNA helicase
NEGKCHNM_00332 3.3e-217 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NEGKCHNM_00333 2.9e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEGKCHNM_00334 1.3e-51 M Lysin motif
NEGKCHNM_00335 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEGKCHNM_00336 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEGKCHNM_00337 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
NEGKCHNM_00338 2.7e-269 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEGKCHNM_00339 5.9e-114 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
NEGKCHNM_00340 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
NEGKCHNM_00341 2.9e-108 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
NEGKCHNM_00342 3.9e-193
NEGKCHNM_00343 4.2e-156 V N-Acetylmuramoyl-L-alanine amidase
NEGKCHNM_00344 3.4e-83
NEGKCHNM_00345 5.4e-57 T helix_turn_helix, Lux Regulon
NEGKCHNM_00346 1.5e-28 2.7.13.3 T Histidine kinase
NEGKCHNM_00347 6.5e-119 ytrE V ATPases associated with a variety of cellular activities
NEGKCHNM_00348 1.6e-208 EGP Major facilitator Superfamily
NEGKCHNM_00349 6.2e-139 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NEGKCHNM_00350 6.2e-132 S Domain of unknown function (DUF5067)
NEGKCHNM_00351 6.6e-69 S Domain of unknown function (DUF5067)
NEGKCHNM_00352 1.3e-201 glnA2 6.3.1.2 E glutamine synthetase
NEGKCHNM_00353 4.6e-57 glnA2 6.3.1.2 E glutamine synthetase
NEGKCHNM_00354 1.4e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
NEGKCHNM_00355 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NEGKCHNM_00356 6.4e-121
NEGKCHNM_00357 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
NEGKCHNM_00358 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NEGKCHNM_00359 2.4e-259 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEGKCHNM_00360 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
NEGKCHNM_00361 5.4e-239 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
NEGKCHNM_00362 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NEGKCHNM_00363 3.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEGKCHNM_00364 1.2e-30 3.1.21.3 V DivIVA protein
NEGKCHNM_00365 1.2e-40 yggT S YGGT family
NEGKCHNM_00366 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEGKCHNM_00367 1.1e-132 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEGKCHNM_00368 5.8e-36 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEGKCHNM_00369 6.3e-204 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEGKCHNM_00370 7.7e-146 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
NEGKCHNM_00371 7.5e-140 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
NEGKCHNM_00372 3e-105 S Pilus assembly protein, PilO
NEGKCHNM_00373 9e-165 pilN NU PFAM Fimbrial assembly family protein
NEGKCHNM_00374 1.7e-64 pilM NU Type IV pilus assembly protein PilM;
NEGKCHNM_00375 4.6e-277 pulE NU Type II/IV secretion system protein
NEGKCHNM_00376 0.0 pilT NU Type II/IV secretion system protein
NEGKCHNM_00377 8.1e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEGKCHNM_00378 2.4e-133 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NEGKCHNM_00379 2.9e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NEGKCHNM_00380 3e-60 S Thiamine-binding protein
NEGKCHNM_00381 3.7e-193 K helix_turn _helix lactose operon repressor
NEGKCHNM_00382 2.8e-241 lacY P LacY proton/sugar symporter
NEGKCHNM_00383 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
NEGKCHNM_00384 1.4e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00385 9.1e-206 P NMT1/THI5 like
NEGKCHNM_00386 1.9e-215 iunH1 3.2.2.1 F nucleoside hydrolase
NEGKCHNM_00387 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEGKCHNM_00388 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
NEGKCHNM_00389 2e-55 I acetylesterase activity
NEGKCHNM_00390 1.1e-251 I acetylesterase activity
NEGKCHNM_00391 3.3e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NEGKCHNM_00392 1e-202 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NEGKCHNM_00393 1.8e-239 2.7.11.1 NU Tfp pilus assembly protein FimV
NEGKCHNM_00395 6.5e-75 S Protein of unknown function (DUF3052)
NEGKCHNM_00396 1e-154 lon T Belongs to the peptidase S16 family
NEGKCHNM_00397 1.7e-285 S Zincin-like metallopeptidase
NEGKCHNM_00398 4.8e-282 uvrD2 3.6.4.12 L DNA helicase
NEGKCHNM_00399 9.4e-270 mphA S Aminoglycoside phosphotransferase
NEGKCHNM_00400 3.6e-32 S Protein of unknown function (DUF3107)
NEGKCHNM_00401 9.2e-167 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
NEGKCHNM_00402 1.8e-116 S Vitamin K epoxide reductase
NEGKCHNM_00403 6.6e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
NEGKCHNM_00404 1e-142 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NEGKCHNM_00405 2.1e-21 S lipid catabolic process
NEGKCHNM_00406 3e-301 E ABC transporter, substrate-binding protein, family 5
NEGKCHNM_00407 8.6e-140 clcA P Voltage gated chloride channel
NEGKCHNM_00408 3.5e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEGKCHNM_00409 1.2e-205 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
NEGKCHNM_00410 0.0 pip S YhgE Pip domain protein
NEGKCHNM_00411 2.7e-82 pip S YhgE Pip domain protein
NEGKCHNM_00412 1.6e-207 pip S YhgE Pip domain protein
NEGKCHNM_00413 2.4e-170 yddG EG EamA-like transporter family
NEGKCHNM_00414 3.8e-187 K Helix-turn-helix XRE-family like proteins
NEGKCHNM_00416 1e-188 htpX O Belongs to the peptidase M48B family
NEGKCHNM_00417 6.9e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
NEGKCHNM_00418 4.3e-267 E aromatic amino acid transport protein AroP K03293
NEGKCHNM_00419 7.9e-188 ansA 3.5.1.1 EJ Asparaginase
NEGKCHNM_00420 2.4e-275 cadA P E1-E2 ATPase
NEGKCHNM_00421 4.5e-118 cadA P E1-E2 ATPase
NEGKCHNM_00422 8.8e-236 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
NEGKCHNM_00423 3.3e-37 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEGKCHNM_00424 4.5e-196 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEGKCHNM_00428 5.7e-159 yicL EG EamA-like transporter family
NEGKCHNM_00429 1e-193 pldB 3.1.1.5 I Serine aminopeptidase, S33
NEGKCHNM_00430 3.2e-113 K helix_turn_helix, Lux Regulon
NEGKCHNM_00431 5.4e-226 2.7.13.3 T Histidine kinase
NEGKCHNM_00432 4.3e-129 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
NEGKCHNM_00433 1.8e-181 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
NEGKCHNM_00434 3.6e-121 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
NEGKCHNM_00435 1.2e-131 fhaA T Protein of unknown function (DUF2662)
NEGKCHNM_00436 9.6e-73 fhaB T Inner membrane component of T3SS, cytoplasmic domain
NEGKCHNM_00437 1e-95 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
NEGKCHNM_00438 2.1e-69 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
NEGKCHNM_00439 1.7e-266 rodA D Belongs to the SEDS family
NEGKCHNM_00440 3e-265 pbpA M penicillin-binding protein
NEGKCHNM_00441 5.8e-177 T Protein tyrosine kinase
NEGKCHNM_00442 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
NEGKCHNM_00443 3.8e-119 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
NEGKCHNM_00444 1.9e-208 srtA 3.4.22.70 M Sortase family
NEGKCHNM_00445 6.8e-142 S Bacterial protein of unknown function (DUF881)
NEGKCHNM_00446 3.1e-57 crgA D Involved in cell division
NEGKCHNM_00447 4.3e-240 L ribosomal rna small subunit methyltransferase
NEGKCHNM_00448 1.4e-147 gluP 3.4.21.105 S Rhomboid family
NEGKCHNM_00449 1.5e-35
NEGKCHNM_00450 4.7e-279 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NEGKCHNM_00451 7.8e-158 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NEGKCHNM_00452 6.3e-63 I Sterol carrier protein
NEGKCHNM_00453 4.9e-42 S Protein of unknown function (DUF3073)
NEGKCHNM_00454 2.2e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NEGKCHNM_00455 2.1e-299 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEGKCHNM_00456 0.0 yjjP S Threonine/Serine exporter, ThrE
NEGKCHNM_00458 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NEGKCHNM_00459 1.1e-38
NEGKCHNM_00460 2.3e-26
NEGKCHNM_00461 7.7e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NEGKCHNM_00462 3.4e-239 ytfL P Transporter associated domain
NEGKCHNM_00463 3.4e-188 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NEGKCHNM_00464 2.5e-101 S Protein of unknown function DUF45
NEGKCHNM_00468 2.9e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEGKCHNM_00469 1.2e-260 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NEGKCHNM_00470 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
NEGKCHNM_00471 5e-28 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEGKCHNM_00472 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEGKCHNM_00473 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEGKCHNM_00474 6.2e-90 S Protein of unknown function (DUF721)
NEGKCHNM_00475 1.5e-77 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEGKCHNM_00476 3.5e-146 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEGKCHNM_00477 7.1e-13 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEGKCHNM_00478 5.1e-176 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEGKCHNM_00479 8.9e-306 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEGKCHNM_00480 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NEGKCHNM_00481 3e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NEGKCHNM_00482 9.6e-173 yidC U Membrane protein insertase, YidC Oxa1 family
NEGKCHNM_00483 3.6e-91 jag S Putative single-stranded nucleic acids-binding domain
NEGKCHNM_00484 2.3e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NEGKCHNM_00485 4.2e-48 parA D CobQ CobB MinD ParA nucleotide binding domain protein
NEGKCHNM_00486 1.3e-114 parA D CobQ CobB MinD ParA nucleotide binding domain protein
NEGKCHNM_00487 1.5e-202 parB K Belongs to the ParB family
NEGKCHNM_00488 2.7e-180 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEGKCHNM_00489 9.1e-14 S Psort location Extracellular, score 8.82
NEGKCHNM_00491 5.2e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NEGKCHNM_00492 4.4e-12 S Domain of unknown function (DUF4143)
NEGKCHNM_00493 0.0 murJ KLT MviN-like protein
NEGKCHNM_00494 8.6e-304 murJ KLT MviN-like protein
NEGKCHNM_00495 1.2e-283 M Conserved repeat domain
NEGKCHNM_00496 4.4e-69 M Conserved repeat domain
NEGKCHNM_00497 1.8e-121 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
NEGKCHNM_00498 2.6e-183 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
NEGKCHNM_00499 8.4e-84 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
NEGKCHNM_00500 2.6e-109 S LytR cell envelope-related transcriptional attenuator
NEGKCHNM_00501 2.5e-102 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEGKCHNM_00502 3.9e-165 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEGKCHNM_00503 4e-39 S G5
NEGKCHNM_00504 2.1e-137 S G5
NEGKCHNM_00506 1.7e-150 O Thioredoxin
NEGKCHNM_00507 0.0 KLT Protein tyrosine kinase
NEGKCHNM_00508 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
NEGKCHNM_00509 1.9e-247 S zinc finger
NEGKCHNM_00510 9.8e-53 S Bacterial PH domain
NEGKCHNM_00511 1.5e-76
NEGKCHNM_00512 2.2e-295 KL Domain of unknown function (DUF3427)
NEGKCHNM_00513 4.1e-71 L Transposase IS200 like
NEGKCHNM_00514 1.1e-222 L Psort location Cytoplasmic, score 8.87
NEGKCHNM_00515 3.4e-21 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NEGKCHNM_00516 7.6e-213 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
NEGKCHNM_00517 4e-67 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
NEGKCHNM_00518 1.3e-187 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
NEGKCHNM_00519 1.5e-70 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NEGKCHNM_00520 4.8e-221 aspB E Aminotransferase class-V
NEGKCHNM_00521 1.2e-113 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
NEGKCHNM_00522 1.5e-39 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
NEGKCHNM_00523 7.7e-100 tmp1 S Domain of unknown function (DUF4391)
NEGKCHNM_00525 2.9e-36 VY92_01845 L Transposase IS200 like
NEGKCHNM_00526 8.9e-30 L COG0675 Transposase and inactivated derivatives
NEGKCHNM_00527 2.5e-195 S Endonuclease/Exonuclease/phosphatase family
NEGKCHNM_00529 2.8e-22 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEGKCHNM_00530 5.4e-161 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEGKCHNM_00531 2.6e-73 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEGKCHNM_00532 3.8e-58 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
NEGKCHNM_00533 1.7e-249 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
NEGKCHNM_00534 2.8e-23 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
NEGKCHNM_00535 5.3e-25 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
NEGKCHNM_00536 1.6e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEGKCHNM_00537 2e-155 hgdC I BadF/BadG/BcrA/BcrD ATPase family
NEGKCHNM_00538 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
NEGKCHNM_00539 1.5e-158 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
NEGKCHNM_00540 9.2e-242 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
NEGKCHNM_00541 4.2e-115 K Bacterial regulatory proteins, tetR family
NEGKCHNM_00542 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
NEGKCHNM_00543 6.5e-108 K Bacterial regulatory proteins, tetR family
NEGKCHNM_00544 7.5e-239 G Transporter major facilitator family protein
NEGKCHNM_00545 9.5e-274 srfJ1 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
NEGKCHNM_00546 7.3e-135 K transcriptional regulator
NEGKCHNM_00547 1.1e-195 blt G MFS/sugar transport protein
NEGKCHNM_00548 3.2e-16 blt G MFS/sugar transport protein
NEGKCHNM_00549 2.2e-311 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NEGKCHNM_00551 6.8e-247 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
NEGKCHNM_00552 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
NEGKCHNM_00553 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
NEGKCHNM_00554 5.2e-113 K Bacterial regulatory proteins, tetR family
NEGKCHNM_00555 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
NEGKCHNM_00556 8e-221 lmrB U Major Facilitator Superfamily
NEGKCHNM_00557 1.4e-43 K helix_turn_helix, mercury resistance
NEGKCHNM_00558 6.3e-13 K helix_turn_helix, mercury resistance
NEGKCHNM_00559 1.3e-116 K Periplasmic binding protein domain
NEGKCHNM_00560 4.4e-215 EGP Major facilitator Superfamily
NEGKCHNM_00561 1e-239 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
NEGKCHNM_00562 1.8e-157 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
NEGKCHNM_00563 3.8e-182 G Transporter major facilitator family protein
NEGKCHNM_00564 1.5e-193 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NEGKCHNM_00565 9.6e-106 K Bacterial regulatory proteins, tetR family
NEGKCHNM_00566 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
NEGKCHNM_00567 1.3e-96 K MarR family
NEGKCHNM_00568 0.0 V ABC transporter, ATP-binding protein
NEGKCHNM_00569 0.0 V ABC transporter transmembrane region
NEGKCHNM_00570 3.4e-29
NEGKCHNM_00571 2.8e-185 lacR K Transcriptional regulator, LacI family
NEGKCHNM_00572 1e-257 lacS G Psort location CytoplasmicMembrane, score 10.00
NEGKCHNM_00573 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEGKCHNM_00574 7.8e-23 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEGKCHNM_00575 5.4e-11
NEGKCHNM_00576 1.6e-81
NEGKCHNM_00577 9.2e-159 cas3 L CRISPR-associated helicase Cas3
NEGKCHNM_00578 1.2e-52 cas3 L CRISPR-associated helicase Cas3
NEGKCHNM_00579 1.4e-94
NEGKCHNM_00580 3.1e-255 cas4 3.1.12.1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NEGKCHNM_00581 1.2e-24 cas2 L CRISPR associated protein Cas2
NEGKCHNM_00582 2.3e-85
NEGKCHNM_00583 6.6e-122 S Phospholipase/Carboxylesterase
NEGKCHNM_00584 1.5e-241 patB 4.4.1.8 E Aminotransferase, class I II
NEGKCHNM_00585 4.3e-186 K LysR substrate binding domain protein
NEGKCHNM_00586 2.2e-159 S Patatin-like phospholipase
NEGKCHNM_00587 4.9e-176 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
NEGKCHNM_00588 3.5e-44
NEGKCHNM_00589 9.4e-80 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
NEGKCHNM_00590 5.7e-39 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
NEGKCHNM_00591 1.9e-62 S Protein of unknown function (DUF4235)
NEGKCHNM_00592 5.4e-135 G Phosphoglycerate mutase family
NEGKCHNM_00593 3.8e-254 amyE G Bacterial extracellular solute-binding protein
NEGKCHNM_00594 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
NEGKCHNM_00595 2.9e-61 K Periplasmic binding protein-like domain
NEGKCHNM_00596 1.6e-97 K Periplasmic binding protein-like domain
NEGKCHNM_00597 1.7e-174 K Psort location Cytoplasmic, score
NEGKCHNM_00598 4.1e-153 msmF G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00599 7.6e-152 rafG G ABC transporter permease
NEGKCHNM_00600 3.4e-106 S Protein of unknown function, DUF624
NEGKCHNM_00601 9.7e-109 pepE 3.4.13.21 E Peptidase family S51
NEGKCHNM_00602 2.9e-13 S Transposon-encoded protein TnpV
NEGKCHNM_00603 8.1e-215 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
NEGKCHNM_00604 1e-190 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
NEGKCHNM_00605 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NEGKCHNM_00606 7e-144 S HAD-hyrolase-like
NEGKCHNM_00607 6.2e-138 traX S TraX protein
NEGKCHNM_00608 4.5e-191 K Psort location Cytoplasmic, score
NEGKCHNM_00609 3.5e-157 srtC 3.4.22.70 M Sortase family
NEGKCHNM_00610 1.7e-125 S membrane transporter protein
NEGKCHNM_00611 8.9e-111 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
NEGKCHNM_00612 1.3e-145 S Mitochondrial biogenesis AIM24
NEGKCHNM_00613 2.8e-52 dnaK O Heat shock 70 kDa protein
NEGKCHNM_00614 1.8e-268 dnaK O Heat shock 70 kDa protein
NEGKCHNM_00615 6e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEGKCHNM_00616 3.9e-158 dnaJ1 O DnaJ molecular chaperone homology domain
NEGKCHNM_00617 3.2e-113 hspR K transcriptional regulator, MerR family
NEGKCHNM_00618 8.6e-47
NEGKCHNM_00619 3.3e-129 S HAD hydrolase, family IA, variant 3
NEGKCHNM_00621 7.5e-52 dedA S SNARE associated Golgi protein
NEGKCHNM_00622 1.8e-60 dedA S SNARE associated Golgi protein
NEGKCHNM_00623 1.6e-17 3.2.1.78 GH26 G Glycosyl hydrolase family 26
NEGKCHNM_00624 5.8e-167 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEGKCHNM_00625 2.5e-106
NEGKCHNM_00626 3.5e-62 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEGKCHNM_00627 2e-213 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEGKCHNM_00628 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NEGKCHNM_00629 6.6e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
NEGKCHNM_00630 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NEGKCHNM_00631 4e-134 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NEGKCHNM_00632 9.7e-262 lacS G Psort location CytoplasmicMembrane, score 10.00
NEGKCHNM_00633 1.4e-209 GK ROK family
NEGKCHNM_00634 2e-239 G Bacterial extracellular solute-binding protein
NEGKCHNM_00635 4.4e-44 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00636 5.7e-86 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00637 4.4e-164 G ABC transporter permease
NEGKCHNM_00638 8.6e-173 2.7.1.2 GK ROK family
NEGKCHNM_00639 1e-110 G Glycosyl hydrolase family 20, domain 2
NEGKCHNM_00640 1.3e-224 G Glycosyl hydrolase family 20, domain 2
NEGKCHNM_00641 1.3e-39 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEGKCHNM_00642 4e-53 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEGKCHNM_00643 4.9e-230 nagA 3.5.1.25 G Amidohydrolase family
NEGKCHNM_00644 1.5e-50 lacR K Transcriptional regulator, LacI family
NEGKCHNM_00645 5.3e-125 lacR K Transcriptional regulator, LacI family
NEGKCHNM_00646 0.0 T Diguanylate cyclase, GGDEF domain
NEGKCHNM_00647 4.5e-252 3.2.1.14 GH18 S Carbohydrate binding domain
NEGKCHNM_00648 4.4e-228 M probably involved in cell wall
NEGKCHNM_00649 1.9e-169 M probably involved in cell wall
NEGKCHNM_00650 7.1e-216 M Protein of unknown function (DUF2961)
NEGKCHNM_00651 1.1e-155 I alpha/beta hydrolase fold
NEGKCHNM_00652 5e-27 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_00653 6.9e-201 lipA I Hydrolase, alpha beta domain protein
NEGKCHNM_00654 2.1e-224 mdlA2 V ABC transporter
NEGKCHNM_00655 0.0 yknV V ABC transporter
NEGKCHNM_00656 8e-126
NEGKCHNM_00657 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
NEGKCHNM_00658 5e-221 K helix_turn _helix lactose operon repressor
NEGKCHNM_00659 2.3e-233 G Alpha galactosidase A
NEGKCHNM_00660 0.0 G Alpha-L-arabinofuranosidase C-terminus
NEGKCHNM_00661 2.2e-184 tatD L TatD related DNase
NEGKCHNM_00662 0.0 kup P Transport of potassium into the cell
NEGKCHNM_00663 1.8e-160 S Glutamine amidotransferase domain
NEGKCHNM_00664 5.1e-150 T HD domain
NEGKCHNM_00665 1.1e-156 V ABC transporter
NEGKCHNM_00666 6.4e-182 V ABC transporter permease
NEGKCHNM_00667 0.0 S Psort location CytoplasmicMembrane, score 9.99
NEGKCHNM_00668 1e-81 U Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00669 4.3e-150 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00670 0.0 G Psort location Cytoplasmic, score 8.87
NEGKCHNM_00671 0.0 O Highly conserved protein containing a thioredoxin domain
NEGKCHNM_00672 1e-228 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
NEGKCHNM_00673 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
NEGKCHNM_00674 8.6e-09 bdhA C Iron-containing alcohol dehydrogenase
NEGKCHNM_00675 3.1e-214 bdhA C Iron-containing alcohol dehydrogenase
NEGKCHNM_00676 2.1e-168 F Inosine-uridine preferring nucleoside hydrolase
NEGKCHNM_00677 2.4e-119 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
NEGKCHNM_00678 3.4e-158 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
NEGKCHNM_00679 1.4e-226 xylR GK ROK family
NEGKCHNM_00680 9.3e-88 ykoE S ABC-type cobalt transport system, permease component
NEGKCHNM_00681 2.2e-12 ydcZ S Putative inner membrane exporter, YdcZ
NEGKCHNM_00682 1.1e-133 ydcZ S Putative inner membrane exporter, YdcZ
NEGKCHNM_00683 1.5e-107 S Membrane
NEGKCHNM_00684 2.9e-148 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NEGKCHNM_00685 1.3e-119 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NEGKCHNM_00686 1.4e-250 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
NEGKCHNM_00687 3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NEGKCHNM_00688 8.3e-226 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
NEGKCHNM_00689 1.2e-94 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
NEGKCHNM_00690 2e-183 K Bacterial regulatory proteins, lacI family
NEGKCHNM_00691 3.9e-93 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
NEGKCHNM_00692 2.5e-98 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
NEGKCHNM_00693 3.4e-186 MA20_14025 U Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00694 4.4e-152 MA20_14020 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00695 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NEGKCHNM_00696 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
NEGKCHNM_00698 2.8e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
NEGKCHNM_00699 1.3e-287 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
NEGKCHNM_00700 5.7e-225 xylR GK ROK family
NEGKCHNM_00702 1.5e-35 rpmE J Binds the 23S rRNA
NEGKCHNM_00703 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEGKCHNM_00704 3.2e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEGKCHNM_00705 1.1e-24 livK E Receptor family ligand binding region
NEGKCHNM_00706 6.2e-185 livK E Receptor family ligand binding region
NEGKCHNM_00707 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
NEGKCHNM_00708 6.7e-196 livM U Belongs to the binding-protein-dependent transport system permease family
NEGKCHNM_00709 1.5e-24 E Branched-chain amino acid ATP-binding cassette transporter
NEGKCHNM_00710 6.9e-110 E Branched-chain amino acid ATP-binding cassette transporter
NEGKCHNM_00711 4e-75 livF E ATPases associated with a variety of cellular activities
NEGKCHNM_00712 2.6e-39 livF E ATPases associated with a variety of cellular activities
NEGKCHNM_00713 3.8e-114 ywlC 2.7.7.87 J Belongs to the SUA5 family
NEGKCHNM_00714 1.7e-194 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
NEGKCHNM_00715 2.5e-161 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NEGKCHNM_00716 1.2e-114 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NEGKCHNM_00717 8.2e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
NEGKCHNM_00718 4.5e-163 supH S Sucrose-6F-phosphate phosphohydrolase
NEGKCHNM_00719 3e-270 recD2 3.6.4.12 L PIF1-like helicase
NEGKCHNM_00720 1.2e-165 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEGKCHNM_00721 1.3e-136 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEGKCHNM_00722 1.2e-29 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEGKCHNM_00723 1.4e-98 L Single-strand binding protein family
NEGKCHNM_00724 0.0 pepO 3.4.24.71 O Peptidase family M13
NEGKCHNM_00725 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
NEGKCHNM_00726 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
NEGKCHNM_00727 5.8e-143 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
NEGKCHNM_00728 4e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEGKCHNM_00729 1.1e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEGKCHNM_00730 2.6e-167 ftsE D Cell division ATP-binding protein FtsE
NEGKCHNM_00731 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
NEGKCHNM_00732 3.8e-148 usp 3.5.1.28 CBM50 D CHAP domain protein
NEGKCHNM_00733 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NEGKCHNM_00734 2.6e-156 pknD ET ABC transporter, substrate-binding protein, family 3
NEGKCHNM_00735 8.9e-32 pknD ET ABC transporter, substrate-binding protein, family 3
NEGKCHNM_00736 3.2e-151 pknD ET ABC transporter, substrate-binding protein, family 3
NEGKCHNM_00737 4.7e-145 yecS E Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00738 1.4e-144 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
NEGKCHNM_00739 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEGKCHNM_00740 1.4e-144 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
NEGKCHNM_00741 3.4e-228 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NEGKCHNM_00742 5.1e-167 K Periplasmic binding protein domain
NEGKCHNM_00743 1.8e-83 K Cro/C1-type HTH DNA-binding domain
NEGKCHNM_00744 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
NEGKCHNM_00745 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NEGKCHNM_00746 1.2e-115 S Short repeat of unknown function (DUF308)
NEGKCHNM_00747 2.7e-49 S Antitoxin component of a toxin-antitoxin (TA) module
NEGKCHNM_00748 3.4e-55 DJ Addiction module toxin, RelE StbE family
NEGKCHNM_00749 4.5e-13 S Psort location Extracellular, score 8.82
NEGKCHNM_00750 9.5e-231 EGP Major facilitator Superfamily
NEGKCHNM_00751 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEGKCHNM_00752 2e-269 KLT Domain of unknown function (DUF4032)
NEGKCHNM_00753 4.1e-17 ugpC E Belongs to the ABC transporter superfamily
NEGKCHNM_00754 5.5e-148 ugpC E Belongs to the ABC transporter superfamily
NEGKCHNM_00755 2.8e-131 K LytTr DNA-binding domain
NEGKCHNM_00756 3.6e-74 T GHKL domain
NEGKCHNM_00757 4.8e-138 T GHKL domain
NEGKCHNM_00758 6.4e-58
NEGKCHNM_00759 6.2e-212 clcA_2 P Voltage gated chloride channel
NEGKCHNM_00760 8.8e-48 S Psort location Cytoplasmic, score
NEGKCHNM_00761 9.9e-146 3.4.22.70 M Sortase family
NEGKCHNM_00762 4e-173 M LPXTG-motif cell wall anchor domain protein
NEGKCHNM_00763 0.0 S LPXTG-motif cell wall anchor domain protein
NEGKCHNM_00764 7.3e-306 S LPXTG-motif cell wall anchor domain protein
NEGKCHNM_00765 1e-72 S GtrA-like protein
NEGKCHNM_00766 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
NEGKCHNM_00767 4.9e-120 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
NEGKCHNM_00768 6.9e-80 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
NEGKCHNM_00769 3.4e-112 vex2 V ABC transporter, ATP-binding protein
NEGKCHNM_00770 4.5e-214 vex1 V Efflux ABC transporter, permease protein
NEGKCHNM_00771 1.3e-241 vex3 V ABC transporter permease
NEGKCHNM_00772 2.3e-111 lacS G Psort location CytoplasmicMembrane, score 10.00
NEGKCHNM_00773 3.8e-12 S Psort location Extracellular, score 8.82
NEGKCHNM_00774 9.7e-43 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NEGKCHNM_00775 6.8e-200 yhjX EGP Major facilitator Superfamily
NEGKCHNM_00776 0.0 trxB1 1.8.1.9 C Thioredoxin domain
NEGKCHNM_00777 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
NEGKCHNM_00778 2.5e-26 thiS 2.8.1.10 H ThiS family
NEGKCHNM_00779 8.4e-128 thiF 2.7.7.73, 2.7.7.80 H ThiF family
NEGKCHNM_00780 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NEGKCHNM_00781 9.9e-275 cycA E Amino acid permease
NEGKCHNM_00782 1.2e-88 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_00783 1.3e-258 M LPXTG cell wall anchor motif
NEGKCHNM_00784 0.0 inlJ M domain protein
NEGKCHNM_00785 3.4e-173 3.4.22.70 M Sortase family
NEGKCHNM_00786 1.3e-76 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_00787 2.7e-229 P Sodium/hydrogen exchanger family
NEGKCHNM_00788 0.0 V FtsX-like permease family
NEGKCHNM_00789 9.2e-142 aroP E aromatic amino acid transport protein AroP K03293
NEGKCHNM_00790 9.5e-81 aroP E aromatic amino acid transport protein AroP K03293
NEGKCHNM_00791 3.7e-14 aroP E aromatic amino acid transport protein AroP K03293
NEGKCHNM_00793 1.5e-186 K helix_turn _helix lactose operon repressor
NEGKCHNM_00794 4.4e-35 G beta-mannosidase
NEGKCHNM_00795 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
NEGKCHNM_00796 7.6e-170 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NEGKCHNM_00797 2e-76 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NEGKCHNM_00798 3.7e-114 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NEGKCHNM_00799 3.5e-252 yhjE EGP Sugar (and other) transporter
NEGKCHNM_00800 3e-115 scrT G Transporter major facilitator family protein
NEGKCHNM_00801 1.9e-153 scrT G Transporter major facilitator family protein
NEGKCHNM_00802 2.7e-149 amyC5 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00803 2.9e-162 amyD3 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00804 3.8e-219 G Bacterial extracellular solute-binding protein
NEGKCHNM_00805 0.0 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
NEGKCHNM_00806 2.7e-105 I alpha/beta hydrolase fold
NEGKCHNM_00807 3.3e-30 I alpha/beta hydrolase fold
NEGKCHNM_00808 2.6e-143 cobB2 K Sir2 family
NEGKCHNM_00809 4.1e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
NEGKCHNM_00810 4.2e-118 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NEGKCHNM_00811 2.2e-240 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NEGKCHNM_00812 3.4e-155 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00813 6.6e-157 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00814 1.5e-244 msmE7 G Bacterial extracellular solute-binding protein
NEGKCHNM_00815 1.5e-230 nagC GK ROK family
NEGKCHNM_00816 1.7e-125 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
NEGKCHNM_00817 4.2e-272 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
NEGKCHNM_00818 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEGKCHNM_00819 0.0 yjcE P Sodium/hydrogen exchanger family
NEGKCHNM_00820 2.7e-154 ypfH S Phospholipase/Carboxylesterase
NEGKCHNM_00821 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
NEGKCHNM_00822 4.3e-75 XK27_00515 D Cell surface antigen C-terminus
NEGKCHNM_00823 0.0 sprF 4.6.1.1 M Cell surface antigen C-terminus
NEGKCHNM_00824 1.1e-98 M domain protein
NEGKCHNM_00825 1.7e-103 S Listeria-Bacteroides repeat domain (List_Bact_rpt)
NEGKCHNM_00826 1.7e-71 M Sortase family
NEGKCHNM_00829 5.4e-206
NEGKCHNM_00830 2.4e-45
NEGKCHNM_00834 7.5e-25
NEGKCHNM_00835 2.1e-104
NEGKCHNM_00837 4.6e-74 S Pfam:CtkA_N
NEGKCHNM_00840 1.4e-51
NEGKCHNM_00841 1.9e-113 S Protein of unknown function, DUF624
NEGKCHNM_00842 1.7e-295 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
NEGKCHNM_00843 3.3e-172 K helix_turn _helix lactose operon repressor
NEGKCHNM_00844 4.1e-29 E Receptor family ligand binding region
NEGKCHNM_00845 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEGKCHNM_00846 9.6e-84 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEGKCHNM_00847 6.1e-132 clcA P Voltage gated chloride channel
NEGKCHNM_00848 3.5e-92 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEGKCHNM_00849 5e-128 V ATPases associated with a variety of cellular activities
NEGKCHNM_00850 3.6e-152 V Efflux ABC transporter, permease protein
NEGKCHNM_00851 1.7e-108 V Efflux ABC transporter, permease protein
NEGKCHNM_00852 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
NEGKCHNM_00853 1.2e-230 dapE 3.5.1.18 E Peptidase dimerisation domain
NEGKCHNM_00854 1.5e-308 rne 3.1.26.12 J Ribonuclease E/G family
NEGKCHNM_00855 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
NEGKCHNM_00856 2.6e-39 rpmA J Ribosomal L27 protein
NEGKCHNM_00857 5.6e-13 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEGKCHNM_00858 9.7e-50 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEGKCHNM_00859 6.5e-218 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEGKCHNM_00860 1.7e-153 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEGKCHNM_00861 5.4e-25 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEGKCHNM_00862 2.2e-232 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
NEGKCHNM_00864 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEGKCHNM_00865 1.2e-127 nusG K Participates in transcription elongation, termination and antitermination
NEGKCHNM_00866 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEGKCHNM_00867 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEGKCHNM_00868 5.9e-143 QT PucR C-terminal helix-turn-helix domain
NEGKCHNM_00869 0.0
NEGKCHNM_00870 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
NEGKCHNM_00871 2.1e-43 bioY S BioY family
NEGKCHNM_00872 7.5e-28 bioY S BioY family
NEGKCHNM_00873 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
NEGKCHNM_00874 0.0 pccB I Carboxyl transferase domain
NEGKCHNM_00875 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
NEGKCHNM_00877 2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEGKCHNM_00878 4.1e-237 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
NEGKCHNM_00879 3.1e-92 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
NEGKCHNM_00880 1.1e-116
NEGKCHNM_00881 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEGKCHNM_00882 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NEGKCHNM_00883 1.7e-91 lemA S LemA family
NEGKCHNM_00884 0.0 S Predicted membrane protein (DUF2207)
NEGKCHNM_00885 9.7e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
NEGKCHNM_00886 7e-297 yegQ O Peptidase family U32 C-terminal domain
NEGKCHNM_00887 3.1e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
NEGKCHNM_00888 2.5e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NEGKCHNM_00889 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NEGKCHNM_00890 2e-59 D nuclear chromosome segregation
NEGKCHNM_00891 3.9e-267 pepC 3.4.22.40 E Peptidase C1-like family
NEGKCHNM_00892 3.3e-211 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NEGKCHNM_00893 6.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NEGKCHNM_00894 3.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEGKCHNM_00895 1.4e-219 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NEGKCHNM_00896 3.4e-129 KT Transcriptional regulatory protein, C terminal
NEGKCHNM_00897 5.9e-24 P Part of the ABC transporter complex PstSACB involved in phosphate import
NEGKCHNM_00898 4.8e-100 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
NEGKCHNM_00899 3.7e-163 pstC P probably responsible for the translocation of the substrate across the membrane
NEGKCHNM_00900 4e-168 pstA P Phosphate transport system permease
NEGKCHNM_00901 2e-120 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEGKCHNM_00902 2.1e-144 P Zinc-uptake complex component A periplasmic
NEGKCHNM_00903 1.3e-246 pbuO S Permease family
NEGKCHNM_00904 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEGKCHNM_00905 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEGKCHNM_00906 5.6e-176 T Forkhead associated domain
NEGKCHNM_00907 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
NEGKCHNM_00908 1.4e-35
NEGKCHNM_00909 1.9e-92 flgA NO SAF
NEGKCHNM_00910 6.1e-30 fmdB S Putative regulatory protein
NEGKCHNM_00911 1.4e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
NEGKCHNM_00912 2.5e-121 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
NEGKCHNM_00913 7.2e-148
NEGKCHNM_00914 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEGKCHNM_00918 5.5e-25 rpmG J Ribosomal protein L33
NEGKCHNM_00919 3.2e-204 murB 1.3.1.98 M Cell wall formation
NEGKCHNM_00920 1.3e-266 E aromatic amino acid transport protein AroP K03293
NEGKCHNM_00921 8.3e-59 fdxA C 4Fe-4S binding domain
NEGKCHNM_00922 2.1e-205 dapC E Aminotransferase class I and II
NEGKCHNM_00924 9.7e-37 E Bacterial extracellular solute-binding proteins, family 5 Middle
NEGKCHNM_00925 8.3e-276 E Bacterial extracellular solute-binding proteins, family 5 Middle
NEGKCHNM_00926 7.7e-180 EP Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00927 3.9e-141 EP Binding-protein-dependent transport system inner membrane component
NEGKCHNM_00928 1.8e-156 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
NEGKCHNM_00929 7.4e-152 dppF E ABC transporter
NEGKCHNM_00930 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NEGKCHNM_00931 1.3e-115 G Psort location Cytoplasmic, score 8.87
NEGKCHNM_00932 4.4e-260 G Psort location Cytoplasmic, score 8.87
NEGKCHNM_00933 4.1e-233 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
NEGKCHNM_00934 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
NEGKCHNM_00935 8.3e-31 CE10 I Belongs to the type-B carboxylesterase lipase family
NEGKCHNM_00936 3.6e-198 CE10 I Belongs to the type-B carboxylesterase lipase family
NEGKCHNM_00938 9.4e-198 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEGKCHNM_00939 2.6e-14 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NEGKCHNM_00940 2.4e-145 M Bacterial capsule synthesis protein PGA_cap
NEGKCHNM_00941 6.3e-93 M Bacterial capsule synthesis protein PGA_cap
NEGKCHNM_00942 3.6e-185 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEGKCHNM_00943 1.2e-91 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
NEGKCHNM_00944 3.1e-122
NEGKCHNM_00945 1.6e-187 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
NEGKCHNM_00946 1.8e-189 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
NEGKCHNM_00947 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEGKCHNM_00948 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
NEGKCHNM_00949 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NEGKCHNM_00950 1.4e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEGKCHNM_00951 1.3e-215 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
NEGKCHNM_00952 3.9e-251 EGP Major facilitator Superfamily
NEGKCHNM_00953 9.5e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
NEGKCHNM_00954 1.6e-182 rhaR_1 K helix_turn_helix, arabinose operon control protein
NEGKCHNM_00955 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NEGKCHNM_00956 5.6e-55 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NEGKCHNM_00957 6.4e-42 rpsJ J Involved in the binding of tRNA to the ribosomes
NEGKCHNM_00958 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEGKCHNM_00959 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
NEGKCHNM_00960 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEGKCHNM_00961 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEGKCHNM_00962 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEGKCHNM_00963 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEGKCHNM_00964 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEGKCHNM_00965 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEGKCHNM_00966 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
NEGKCHNM_00967 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEGKCHNM_00968 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEGKCHNM_00969 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEGKCHNM_00970 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEGKCHNM_00971 1.6e-17 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEGKCHNM_00972 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEGKCHNM_00973 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEGKCHNM_00974 1.3e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEGKCHNM_00975 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEGKCHNM_00976 3.4e-25 rpmD J Ribosomal protein L30p/L7e
NEGKCHNM_00977 9.8e-74 rplO J binds to the 23S rRNA
NEGKCHNM_00978 3.8e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEGKCHNM_00979 5.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEGKCHNM_00980 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEGKCHNM_00981 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NEGKCHNM_00982 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEGKCHNM_00983 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEGKCHNM_00984 2.5e-178 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEGKCHNM_00985 1.3e-66 rplQ J Ribosomal protein L17
NEGKCHNM_00986 4.4e-183 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEGKCHNM_00987 1.3e-63 gcs2 S A circularly permuted ATPgrasp
NEGKCHNM_00988 7.4e-70 gcs2 S A circularly permuted ATPgrasp
NEGKCHNM_00990 1.1e-116
NEGKCHNM_00991 1.3e-190 nusA K Participates in both transcription termination and antitermination
NEGKCHNM_00992 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEGKCHNM_00993 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEGKCHNM_00994 5.1e-188 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEGKCHNM_00995 7.5e-217 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
NEGKCHNM_00996 7.4e-56 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEGKCHNM_00997 2.2e-98 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEGKCHNM_00998 6.6e-70 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEGKCHNM_00999 5.5e-107
NEGKCHNM_01001 2.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NEGKCHNM_01002 3.9e-213 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEGKCHNM_01003 3e-251 T GHKL domain
NEGKCHNM_01004 2.3e-150 T LytTr DNA-binding domain
NEGKCHNM_01005 3.6e-07 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
NEGKCHNM_01006 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
NEGKCHNM_01007 0.0 crr G pts system, glucose-specific IIABC component
NEGKCHNM_01008 6.4e-154 arbG K CAT RNA binding domain
NEGKCHNM_01009 2.5e-185 tetP J elongation factor Tu domain 2 protein
NEGKCHNM_01010 4e-95 tetP J elongation factor G
NEGKCHNM_01011 2e-113 S Psort location Cytoplasmic, score
NEGKCHNM_01012 4.6e-36 L Domain of unknown function (DUF4368)
NEGKCHNM_01013 1e-220 L Domain of unknown function (DUF4368)
NEGKCHNM_01014 3.7e-99 U Psort location Cytoplasmic, score
NEGKCHNM_01015 4.5e-77 S Protein of unknown function (DUF3801)
NEGKCHNM_01016 3e-36 S Domain of unknown function (DUF5348)
NEGKCHNM_01017 3.4e-187 L Psort location Cytoplasmic, score 8.87
NEGKCHNM_01018 4.6e-197 I Diacylglycerol kinase catalytic domain
NEGKCHNM_01019 1.2e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEGKCHNM_01021 1.9e-121 degU K helix_turn_helix, Lux Regulon
NEGKCHNM_01022 3.3e-281 tcsS3 KT PspC domain
NEGKCHNM_01023 8.3e-146 pspC KT PspC domain
NEGKCHNM_01024 6e-92
NEGKCHNM_01025 7.9e-88 S Protein of unknown function (DUF4125)
NEGKCHNM_01026 7.3e-74 S Domain of unknown function (DUF4037)
NEGKCHNM_01027 5.7e-287 S Domain of unknown function (DUF4037)
NEGKCHNM_01028 7.5e-214 araJ EGP Major facilitator Superfamily
NEGKCHNM_01030 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NEGKCHNM_01031 4.5e-194 K helix_turn _helix lactose operon repressor
NEGKCHNM_01032 3.3e-250 G Psort location CytoplasmicMembrane, score 10.00
NEGKCHNM_01033 4.1e-99 S Serine aminopeptidase, S33
NEGKCHNM_01034 2e-205 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NEGKCHNM_01035 3e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEGKCHNM_01036 0.0 4.2.1.53 S MCRA family
NEGKCHNM_01037 1.7e-34 4.2.1.53 S MCRA family
NEGKCHNM_01038 9e-87 phoU P Plays a role in the regulation of phosphate uptake
NEGKCHNM_01039 4.7e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEGKCHNM_01040 6.2e-41
NEGKCHNM_01041 8.1e-28 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NEGKCHNM_01042 2.5e-156 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NEGKCHNM_01043 5.1e-165 usp 3.5.1.28 CBM50 S CHAP domain
NEGKCHNM_01044 1.3e-79 M NlpC/P60 family
NEGKCHNM_01045 6.6e-190 T Universal stress protein family
NEGKCHNM_01046 1e-72 attW O OsmC-like protein
NEGKCHNM_01047 8.4e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEGKCHNM_01048 1.1e-129 folA 1.5.1.3 H dihydrofolate reductase
NEGKCHNM_01049 3.6e-85 ptpA 3.1.3.48 T low molecular weight
NEGKCHNM_01051 7.6e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NEGKCHNM_01052 2.7e-163 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEGKCHNM_01056 6.2e-32 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
NEGKCHNM_01057 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
NEGKCHNM_01058 1.1e-98
NEGKCHNM_01059 2.8e-82 S Uncharacterised protein conserved in bacteria (DUF2194)
NEGKCHNM_01060 7.8e-271 S Uncharacterised protein conserved in bacteria (DUF2194)
NEGKCHNM_01061 4.9e-284 pelF GT4 M Domain of unknown function (DUF3492)
NEGKCHNM_01062 4e-145 pelG S Putative exopolysaccharide Exporter (EPS-E)
NEGKCHNM_01063 7.4e-124 pelG S Putative exopolysaccharide Exporter (EPS-E)
NEGKCHNM_01064 5.5e-309 cotH M CotH kinase protein
NEGKCHNM_01065 2.4e-158 P VTC domain
NEGKCHNM_01066 2.2e-111 S Domain of unknown function (DUF4956)
NEGKCHNM_01067 0.0 yliE T Putative diguanylate phosphodiesterase
NEGKCHNM_01068 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
NEGKCHNM_01069 9.5e-180 3.4.14.13 M Glycosyltransferase like family 2
NEGKCHNM_01070 1.8e-236 S AI-2E family transporter
NEGKCHNM_01071 5.3e-231 epsG M Glycosyl transferase family 21
NEGKCHNM_01073 3.8e-252 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
NEGKCHNM_01074 3.7e-174 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEGKCHNM_01075 6.1e-68 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NEGKCHNM_01076 1.1e-17 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NEGKCHNM_01077 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEGKCHNM_01078 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
NEGKCHNM_01079 1.1e-153 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NEGKCHNM_01080 8.9e-252 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NEGKCHNM_01081 1.1e-93 S Protein of unknown function (DUF3180)
NEGKCHNM_01082 5e-165 tesB I Thioesterase-like superfamily
NEGKCHNM_01083 3e-226 yjjK S ATP-binding cassette protein, ChvD family
NEGKCHNM_01084 3.2e-180 V Beta-lactamase
NEGKCHNM_01085 5.5e-74 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NEGKCHNM_01086 4.2e-106 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
NEGKCHNM_01087 1.4e-175 G ABC transporter periplasmic binding protein YcjN precursor K02027
NEGKCHNM_01088 2e-70 G ABC transporter periplasmic binding protein YcjN precursor K02027
NEGKCHNM_01089 1.4e-33 DJ Addiction module toxin, RelE StbE family
NEGKCHNM_01090 2.4e-26 S Antitoxin component of a toxin-antitoxin (TA) module
NEGKCHNM_01092 1.3e-06 ssb1 L Single-stranded DNA-binding protein
NEGKCHNM_01093 1.2e-25 S Domain of unknown function (DUF3846)
NEGKCHNM_01095 4.3e-55 KLT Protein tyrosine kinase
NEGKCHNM_01096 7.4e-259 EGP Transmembrane secretion effector
NEGKCHNM_01097 3.3e-155 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
NEGKCHNM_01098 2.8e-22 V Type II restriction enzyme, methylase subunits
NEGKCHNM_01099 1.4e-165 G ABC transporter permease
NEGKCHNM_01100 2.8e-146 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01101 8.4e-107 L Belongs to the 'phage' integrase family
NEGKCHNM_01102 8.2e-39 3.1.21.3 L Type I restriction modification DNA specificity domain
NEGKCHNM_01103 3.8e-29 L transposase activity
NEGKCHNM_01104 9.3e-108 L Transposase and inactivated derivatives
NEGKCHNM_01105 2e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NEGKCHNM_01106 1.5e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEGKCHNM_01107 0.0 pgi 5.3.1.9 G Belongs to the GPI family
NEGKCHNM_01108 1.3e-179 S Auxin Efflux Carrier
NEGKCHNM_01111 1.4e-83 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
NEGKCHNM_01112 4.9e-15 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
NEGKCHNM_01113 4.1e-89 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
NEGKCHNM_01114 2.1e-238 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
NEGKCHNM_01115 1.1e-250 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEGKCHNM_01116 1.9e-138 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NEGKCHNM_01117 5.2e-119 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEGKCHNM_01118 9.2e-77 soxR K MerR, DNA binding
NEGKCHNM_01119 1.7e-195 yghZ C Aldo/keto reductase family
NEGKCHNM_01120 3.2e-58 S Protein of unknown function (DUF3039)
NEGKCHNM_01121 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEGKCHNM_01122 5.2e-131
NEGKCHNM_01123 1.8e-113 yceD S Uncharacterized ACR, COG1399
NEGKCHNM_01124 1.7e-22 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NEGKCHNM_01125 4.6e-14 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEGKCHNM_01126 3.9e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEGKCHNM_01127 2e-17 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
NEGKCHNM_01128 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
NEGKCHNM_01129 5.7e-92 ilvN 2.2.1.6 E ACT domain
NEGKCHNM_01130 2.4e-110 S Domain of unknown function (DUF4143)
NEGKCHNM_01131 4.2e-121 S Domain of unknown function (DUF4143)
NEGKCHNM_01133 3.9e-93
NEGKCHNM_01134 2.1e-13 yjjK S ABC transporter
NEGKCHNM_01135 0.0 yjjK S ABC transporter
NEGKCHNM_01136 1.1e-148 guaA1 6.3.5.2 F Peptidase C26
NEGKCHNM_01137 2.5e-295 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
NEGKCHNM_01138 2.7e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEGKCHNM_01139 3.7e-177 S Endonuclease/Exonuclease/phosphatase family
NEGKCHNM_01140 1.4e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NEGKCHNM_01141 6.4e-11 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NEGKCHNM_01142 1.8e-34 CP_0960 S Belongs to the UPF0109 family
NEGKCHNM_01143 3.7e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEGKCHNM_01144 3.1e-152 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NEGKCHNM_01145 6.5e-105 rsmD 2.1.1.171 L Conserved hypothetical protein 95
NEGKCHNM_01146 3.8e-38 recG 3.6.4.12 L helicase superfamily c-terminal domain
NEGKCHNM_01147 4.2e-265 recG 3.6.4.12 L helicase superfamily c-terminal domain
NEGKCHNM_01148 4.7e-155 recG 3.6.4.12 L helicase superfamily c-terminal domain
NEGKCHNM_01149 8.4e-30 rpmB J Ribosomal L28 family
NEGKCHNM_01150 0.0 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_01151 5.4e-229 yxiO S Vacuole effluxer Atg22 like
NEGKCHNM_01152 1.9e-127 gntR K FCD
NEGKCHNM_01153 1.6e-77 gntK 2.7.1.12 F Shikimate kinase
NEGKCHNM_01155 6e-228 gnuT EG GntP family permease
NEGKCHNM_01157 5.2e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
NEGKCHNM_01158 1.6e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
NEGKCHNM_01159 4.5e-123 K Bacterial regulatory proteins, tetR family
NEGKCHNM_01160 7.1e-228 MA20_36090 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_01161 5.2e-116 MA20_36090 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_01162 3.8e-56 MA20_36090 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_01163 1.7e-137 M Mechanosensitive ion channel
NEGKCHNM_01164 8.7e-172 S CAAX protease self-immunity
NEGKCHNM_01165 7.3e-138 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NEGKCHNM_01166 7.1e-68 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NEGKCHNM_01167 1.7e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NEGKCHNM_01168 2.3e-175 plsC2 2.3.1.51 I Phosphate acyltransferases
NEGKCHNM_01169 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEGKCHNM_01170 2.3e-181 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
NEGKCHNM_01171 1.3e-10 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
NEGKCHNM_01172 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEGKCHNM_01173 5.9e-42 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEGKCHNM_01174 6.6e-170 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEGKCHNM_01175 8.2e-140 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
NEGKCHNM_01176 3e-268 S Calcineurin-like phosphoesterase
NEGKCHNM_01179 2.8e-38 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEGKCHNM_01180 2.1e-132 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEGKCHNM_01181 2.5e-93 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEGKCHNM_01183 1.7e-108 S Protein of unknown function (DUF805)
NEGKCHNM_01184 7e-184
NEGKCHNM_01185 9.9e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
NEGKCHNM_01186 8e-263 EGP Major facilitator Superfamily
NEGKCHNM_01187 6.4e-96 S GtrA-like protein
NEGKCHNM_01188 2.3e-62 S Macrophage migration inhibitory factor (MIF)
NEGKCHNM_01189 2e-288 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
NEGKCHNM_01190 0.0 pepD E Peptidase family C69
NEGKCHNM_01191 1.1e-106 S Phosphatidylethanolamine-binding protein
NEGKCHNM_01192 1e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEGKCHNM_01193 6e-39 ptsH G PTS HPr component phosphorylation site
NEGKCHNM_01194 5.4e-184 K helix_turn _helix lactose operon repressor
NEGKCHNM_01195 1.1e-154 holB 2.7.7.7 L DNA polymerase III
NEGKCHNM_01196 1e-21 holB 2.7.7.7 L DNA polymerase III
NEGKCHNM_01197 3.4e-60 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEGKCHNM_01198 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEGKCHNM_01199 9.7e-186 3.6.1.27 I PAP2 superfamily
NEGKCHNM_01200 1.1e-110 glf 5.4.99.9 M UDP-galactopyranose mutase
NEGKCHNM_01201 1.5e-109 glf 5.4.99.9 M UDP-galactopyranose mutase
NEGKCHNM_01202 8.5e-215 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
NEGKCHNM_01203 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
NEGKCHNM_01204 0.0 S Beta-L-arabinofuranosidase, GH127
NEGKCHNM_01205 7.3e-36 U Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01206 9.2e-90 U Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01207 1.2e-115 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01208 1.3e-10 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01209 2e-244 G Bacterial extracellular solute-binding protein
NEGKCHNM_01210 1.3e-203 abf G Glycosyl hydrolases family 43
NEGKCHNM_01211 1.1e-195 K helix_turn _helix lactose operon repressor
NEGKCHNM_01212 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
NEGKCHNM_01213 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
NEGKCHNM_01214 1.9e-36 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
NEGKCHNM_01215 8.4e-267 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
NEGKCHNM_01216 2.6e-146 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NEGKCHNM_01217 6e-202 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NEGKCHNM_01218 2.3e-303 S Calcineurin-like phosphoesterase
NEGKCHNM_01219 2.4e-115
NEGKCHNM_01220 2.7e-48 yitI S Acetyltransferase (GNAT) domain
NEGKCHNM_01221 6.1e-210 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEGKCHNM_01222 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
NEGKCHNM_01223 9.4e-124 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
NEGKCHNM_01224 4.5e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEGKCHNM_01225 7.2e-68 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
NEGKCHNM_01226 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
NEGKCHNM_01227 1.9e-96 K Bacterial regulatory proteins, tetR family
NEGKCHNM_01228 3e-192 S Psort location CytoplasmicMembrane, score
NEGKCHNM_01229 2.3e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
NEGKCHNM_01230 1.9e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
NEGKCHNM_01231 4.3e-59 U TadE-like protein
NEGKCHNM_01232 1.3e-42 S Protein of unknown function (DUF4244)
NEGKCHNM_01233 1.7e-88 gspF NU Type II secretion system (T2SS), protein F
NEGKCHNM_01234 6.9e-125 U Type ii secretion system
NEGKCHNM_01235 1.3e-182 cpaF U Type II IV secretion system protein
NEGKCHNM_01236 5.5e-141 cpaE D bacterial-type flagellum organization
NEGKCHNM_01237 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NEGKCHNM_01238 3.8e-85 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
NEGKCHNM_01239 6.2e-44 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
NEGKCHNM_01240 4.4e-58 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
NEGKCHNM_01241 3.9e-91
NEGKCHNM_01242 4.6e-88 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEGKCHNM_01243 6.8e-20 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEGKCHNM_01244 1.6e-207 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NEGKCHNM_01245 0.0 G Bacterial Ig-like domain (group 4)
NEGKCHNM_01246 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
NEGKCHNM_01247 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
NEGKCHNM_01248 6.4e-156 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
NEGKCHNM_01249 3.5e-224 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
NEGKCHNM_01250 2.7e-49 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01251 2.4e-76 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01252 3.1e-167 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01253 2.8e-08 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01254 1.1e-242 G Bacterial extracellular solute-binding protein
NEGKCHNM_01255 2.4e-192 K Periplasmic binding protein domain
NEGKCHNM_01256 0.0 ubiB S ABC1 family
NEGKCHNM_01257 1e-27 S granule-associated protein
NEGKCHNM_01258 3.6e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NEGKCHNM_01259 2.7e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
NEGKCHNM_01260 7.1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NEGKCHNM_01261 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
NEGKCHNM_01262 7.7e-55 glnB K Nitrogen regulatory protein P-II
NEGKCHNM_01263 1.5e-236 amt U Ammonium Transporter Family
NEGKCHNM_01264 6.7e-80 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEGKCHNM_01266 4.9e-108 icaR K Bacterial regulatory proteins, tetR family
NEGKCHNM_01267 4.4e-194 XK27_01805 M Glycosyltransferase like family 2
NEGKCHNM_01268 4.3e-308 pepD E Peptidase family C69
NEGKCHNM_01270 8.5e-18 M cell wall organization
NEGKCHNM_01272 1.7e-37 nrdH O Glutaredoxin
NEGKCHNM_01273 1.6e-225 S Putative ABC-transporter type IV
NEGKCHNM_01274 0.0 pip S YhgE Pip domain protein
NEGKCHNM_01275 5.7e-276 pip S YhgE Pip domain protein
NEGKCHNM_01276 7.8e-88 K Psort location Cytoplasmic, score 8.87
NEGKCHNM_01277 1.1e-61 S FMN_bind
NEGKCHNM_01278 1e-148 macB V ABC transporter, ATP-binding protein
NEGKCHNM_01279 5.4e-202 Z012_06715 V FtsX-like permease family
NEGKCHNM_01280 3e-131 macB_2 V ABC transporter permease
NEGKCHNM_01281 2.9e-63 macB_2 V ABC transporter permease
NEGKCHNM_01282 2.2e-227 S Predicted membrane protein (DUF2318)
NEGKCHNM_01283 2.4e-92 tpd P Fe2+ transport protein
NEGKCHNM_01284 4.3e-298 efeU_1 P Iron permease FTR1 family
NEGKCHNM_01285 4.4e-237 G MFS/sugar transport protein
NEGKCHNM_01286 1.3e-115 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEGKCHNM_01287 0.0 lmrA2 V ABC transporter transmembrane region
NEGKCHNM_01288 2.1e-285 lmrA1 V ABC transporter, ATP-binding protein
NEGKCHNM_01289 1.9e-57 ydgJ K helix_turn_helix multiple antibiotic resistance protein
NEGKCHNM_01290 1.7e-155 1.1.1.65 C Aldo/keto reductase family
NEGKCHNM_01291 2.6e-250 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NEGKCHNM_01292 2.8e-145 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NEGKCHNM_01293 0.0 abfA1 3.2.1.55 GH51 G arabinose metabolic process
NEGKCHNM_01294 2.2e-246 G Bacterial extracellular solute-binding protein
NEGKCHNM_01295 1.5e-79 G Bacterial extracellular solute-binding protein
NEGKCHNM_01296 8e-168 G Bacterial extracellular solute-binding protein
NEGKCHNM_01297 2.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NEGKCHNM_01298 2.3e-240 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NEGKCHNM_01299 3.2e-196 E ABC transporter, substrate-binding protein, family 5
NEGKCHNM_01300 1.8e-24 E ABC transporter, substrate-binding protein, family 5
NEGKCHNM_01301 4.7e-60 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01302 2.2e-39 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01303 1.3e-28 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01304 8.3e-27 EP Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01305 2.6e-103 EP Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01306 7.1e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
NEGKCHNM_01307 4e-139 sapF E ATPases associated with a variety of cellular activities
NEGKCHNM_01308 2.8e-36 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
NEGKCHNM_01309 2.1e-131 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
NEGKCHNM_01310 1e-218 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NEGKCHNM_01311 0.0 macB_2 V ATPases associated with a variety of cellular activities
NEGKCHNM_01312 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NEGKCHNM_01313 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEGKCHNM_01314 2.7e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NEGKCHNM_01315 4.4e-269 yhdG E aromatic amino acid transport protein AroP K03293
NEGKCHNM_01316 5.9e-307 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEGKCHNM_01317 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEGKCHNM_01318 2e-214 ybiR P Citrate transporter
NEGKCHNM_01319 9.9e-130 ydcZ S Putative inner membrane exporter, YdcZ
NEGKCHNM_01321 0.0 tetP J Elongation factor G, domain IV
NEGKCHNM_01325 2.7e-114 K acetyltransferase
NEGKCHNM_01326 1.1e-108 papP E Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01327 3.6e-120 E Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01328 6.5e-151 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
NEGKCHNM_01329 6.9e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
NEGKCHNM_01330 9.1e-200 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEGKCHNM_01331 2.3e-151 metQ M NLPA lipoprotein
NEGKCHNM_01332 6.3e-180 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEGKCHNM_01333 2.4e-97 metI P Psort location CytoplasmicMembrane, score 9.99
NEGKCHNM_01334 7e-220 mtnE 2.6.1.83 E Aminotransferase class I and II
NEGKCHNM_01335 4.3e-13 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NEGKCHNM_01336 4.3e-75 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NEGKCHNM_01337 2.8e-15 P Belongs to the ABC transporter superfamily
NEGKCHNM_01338 1.4e-43 XAC3035 O Glutaredoxin
NEGKCHNM_01339 3.1e-127 XK27_08050 O prohibitin homologues
NEGKCHNM_01340 2.4e-15 S Domain of unknown function (DUF4143)
NEGKCHNM_01341 4.3e-75
NEGKCHNM_01342 4.2e-66 V ATPases associated with a variety of cellular activities
NEGKCHNM_01343 2e-58 V ATPases associated with a variety of cellular activities
NEGKCHNM_01344 6e-103 M Conserved repeat domain
NEGKCHNM_01345 2.2e-32 M Conserved repeat domain
NEGKCHNM_01346 3.4e-256 macB_8 V MacB-like periplasmic core domain
NEGKCHNM_01347 1.6e-38 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEGKCHNM_01348 2.5e-287 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEGKCHNM_01349 1.2e-183 adh3 C Zinc-binding dehydrogenase
NEGKCHNM_01350 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEGKCHNM_01351 1.9e-225 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEGKCHNM_01352 8.8e-71 zur P Belongs to the Fur family
NEGKCHNM_01353 4.9e-203 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
NEGKCHNM_01354 4.4e-160 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
NEGKCHNM_01355 2.7e-202 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
NEGKCHNM_01356 2.7e-188 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
NEGKCHNM_01357 1.9e-112 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
NEGKCHNM_01358 2.1e-213 1.1.1.1 C Iron-containing alcohol dehydrogenase
NEGKCHNM_01359 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NEGKCHNM_01360 2.1e-247 EGP Major facilitator Superfamily
NEGKCHNM_01361 2.8e-235 purD 6.3.4.13 F Belongs to the GARS family
NEGKCHNM_01362 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NEGKCHNM_01363 1e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEGKCHNM_01364 3.6e-307 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
NEGKCHNM_01365 5.8e-30
NEGKCHNM_01366 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
NEGKCHNM_01367 1.3e-51 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
NEGKCHNM_01368 1.5e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NEGKCHNM_01369 1.6e-175 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NEGKCHNM_01370 6.5e-226 M Glycosyl transferase 4-like domain
NEGKCHNM_01371 1.5e-197 ltaE 4.1.2.48 E Beta-eliminating lyase
NEGKCHNM_01373 1.8e-187 yocS S SBF-like CPA transporter family (DUF4137)
NEGKCHNM_01374 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEGKCHNM_01375 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEGKCHNM_01376 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEGKCHNM_01377 9.5e-233 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEGKCHNM_01378 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEGKCHNM_01379 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEGKCHNM_01380 2.4e-239 carA 6.3.5.5 F Belongs to the CarA family
NEGKCHNM_01381 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NEGKCHNM_01382 5.4e-104 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NEGKCHNM_01383 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NEGKCHNM_01385 7.7e-285 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
NEGKCHNM_01386 6e-59 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
NEGKCHNM_01387 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEGKCHNM_01388 1e-61 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEGKCHNM_01389 1.5e-147 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEGKCHNM_01390 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEGKCHNM_01391 5.6e-45 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NEGKCHNM_01392 1.2e-79 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NEGKCHNM_01393 1.1e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEGKCHNM_01394 3.5e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
NEGKCHNM_01395 4.4e-283 arc O AAA ATPase forming ring-shaped complexes
NEGKCHNM_01396 6.7e-301 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
NEGKCHNM_01397 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
NEGKCHNM_01398 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
NEGKCHNM_01399 5.3e-278 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NEGKCHNM_01400 9.7e-141 C FMN binding
NEGKCHNM_01401 1.8e-57
NEGKCHNM_01402 1.4e-41 hup L Belongs to the bacterial histone-like protein family
NEGKCHNM_01403 0.0 S Lysylphosphatidylglycerol synthase TM region
NEGKCHNM_01404 8.6e-136 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
NEGKCHNM_01405 1.5e-133 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
NEGKCHNM_01406 2.2e-260 S PGAP1-like protein
NEGKCHNM_01407 7.1e-61
NEGKCHNM_01408 4.1e-182 S von Willebrand factor (vWF) type A domain
NEGKCHNM_01409 5.7e-178 S von Willebrand factor (vWF) type A domain
NEGKCHNM_01410 6.7e-90
NEGKCHNM_01411 1.6e-174 S Protein of unknown function DUF58
NEGKCHNM_01412 3.1e-81 moxR S ATPase family associated with various cellular activities (AAA)
NEGKCHNM_01413 1.8e-67 moxR S ATPase family associated with various cellular activities (AAA)
NEGKCHNM_01414 1e-68 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEGKCHNM_01415 1.7e-47 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEGKCHNM_01416 8.5e-77 S LytR cell envelope-related transcriptional attenuator
NEGKCHNM_01417 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEGKCHNM_01419 7.3e-123
NEGKCHNM_01420 6.8e-133 KT Response regulator receiver domain protein
NEGKCHNM_01421 8e-261 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEGKCHNM_01422 2.2e-54 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEGKCHNM_01423 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
NEGKCHNM_01424 2.3e-167 S Protein of unknown function (DUF3027)
NEGKCHNM_01426 9.9e-132 uspA T Belongs to the universal stress protein A family
NEGKCHNM_01427 1.9e-43 uspA T Belongs to the universal stress protein A family
NEGKCHNM_01428 0.0 clpC O ATPase family associated with various cellular activities (AAA)
NEGKCHNM_01429 2.9e-93 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
NEGKCHNM_01430 6.3e-122 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
NEGKCHNM_01431 6.2e-285 purR QT Purine catabolism regulatory protein-like family
NEGKCHNM_01432 4.7e-244 proP EGP Sugar (and other) transporter
NEGKCHNM_01433 7e-60 3.5.2.10 S Creatinine amidohydrolase
NEGKCHNM_01434 2.5e-61 3.5.2.10 S Creatinine amidohydrolase
NEGKCHNM_01435 6.9e-222 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
NEGKCHNM_01436 2.4e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
NEGKCHNM_01437 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NEGKCHNM_01438 2.6e-275 glnP E Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01439 3.1e-119 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
NEGKCHNM_01440 2.7e-135 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
NEGKCHNM_01441 6.7e-78 gluB ET Belongs to the bacterial solute-binding protein 3 family
NEGKCHNM_01442 1.4e-65 gluB ET Belongs to the bacterial solute-binding protein 3 family
NEGKCHNM_01443 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01444 1e-199 gluD E Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01445 4.3e-191 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
NEGKCHNM_01446 0.0 L DEAD DEAH box helicase
NEGKCHNM_01447 1.8e-188 rarA L Recombination factor protein RarA
NEGKCHNM_01448 1.7e-46 rarA L Recombination factor protein RarA
NEGKCHNM_01449 1.3e-61 KT Transcriptional regulatory protein, C terminal
NEGKCHNM_01450 8.1e-38 KT Transcriptional regulatory protein, C terminal
NEGKCHNM_01451 4.4e-286 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NEGKCHNM_01452 0.0 lpqB S Lipoprotein LpqB beta-propeller domain
NEGKCHNM_01453 2.4e-165 G Periplasmic binding protein domain
NEGKCHNM_01454 6e-288 ytfR 3.6.3.17 G ATPases associated with a variety of cellular activities
NEGKCHNM_01455 1.5e-181 ytfT U Branched-chain amino acid transport system / permease component
NEGKCHNM_01456 6.1e-172 yjfF U Branched-chain amino acid transport system / permease component
NEGKCHNM_01457 2.4e-244 EGP Major facilitator Superfamily
NEGKCHNM_01458 2.3e-309 E ABC transporter, substrate-binding protein, family 5
NEGKCHNM_01459 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEGKCHNM_01460 1.6e-85 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEGKCHNM_01461 1.7e-180 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEGKCHNM_01462 4.3e-14 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEGKCHNM_01464 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
NEGKCHNM_01465 1.1e-195 K helix_turn _helix lactose operon repressor
NEGKCHNM_01466 2.1e-241 mntH P H( )-stimulated, divalent metal cation uptake system
NEGKCHNM_01467 9.3e-166 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
NEGKCHNM_01468 2.3e-126 L Protein of unknown function (DUF1524)
NEGKCHNM_01469 3.7e-243 T Diguanylate cyclase (GGDEF) domain protein
NEGKCHNM_01470 5.8e-283 EGP Major facilitator Superfamily
NEGKCHNM_01471 2.5e-47
NEGKCHNM_01472 2.9e-30 S Endonuclease/Exonuclease/phosphatase family
NEGKCHNM_01473 1.1e-33 S Endonuclease/Exonuclease/phosphatase family
NEGKCHNM_01474 7.5e-12 S Endonuclease/Exonuclease/phosphatase family
NEGKCHNM_01475 4.1e-86 3.1.3.48 T Low molecular weight phosphatase family
NEGKCHNM_01476 7.9e-223 pflA S Protein of unknown function (DUF4012)
NEGKCHNM_01477 1.9e-190 wcoI DM Psort location CytoplasmicMembrane, score
NEGKCHNM_01478 1.2e-20
NEGKCHNM_01479 5e-110
NEGKCHNM_01480 5.5e-43 V Abi-like protein
NEGKCHNM_01481 3e-164 O Subtilase family
NEGKCHNM_01482 1.5e-93 O Subtilase family
NEGKCHNM_01483 2.3e-145 O ATPase family associated with various cellular activities (AAA)
NEGKCHNM_01484 6.2e-13 S YjzC-like protein
NEGKCHNM_01485 1.9e-93 L PFAM Integrase catalytic
NEGKCHNM_01486 1e-141 G Acyltransferase family
NEGKCHNM_01487 7.5e-220 rfbX S polysaccharide biosynthetic process
NEGKCHNM_01488 1e-187 1.13.11.79 C Psort location Cytoplasmic, score 8.87
NEGKCHNM_01489 2.7e-210 S Polysaccharide pyruvyl transferase
NEGKCHNM_01490 4.5e-194 S Glycosyltransferase like family 2
NEGKCHNM_01491 2.3e-59
NEGKCHNM_01492 3.1e-131 cps1D M Domain of unknown function (DUF4422)
NEGKCHNM_01493 5.4e-147 M Psort location Cytoplasmic, score 8.87
NEGKCHNM_01494 1.7e-95 M Glycosyltransferase, group 1 family protein
NEGKCHNM_01495 2.7e-16 S Psort location CytoplasmicMembrane, score
NEGKCHNM_01496 2.4e-104 M Glycosyltransferase like family 2
NEGKCHNM_01497 1.9e-59 2.3.1.30 E serine acetyltransferase
NEGKCHNM_01498 5.5e-78 S Polysaccharide pyruvyl transferase
NEGKCHNM_01499 6.8e-220 S Polysaccharide biosynthesis protein
NEGKCHNM_01500 5.7e-225 1.12.98.1 C Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term
NEGKCHNM_01501 1e-78 1.13.11.79 C Psort location Cytoplasmic, score 8.87
NEGKCHNM_01502 2.2e-22 I Acyltransferase family
NEGKCHNM_01504 4.8e-47
NEGKCHNM_01505 2.6e-47
NEGKCHNM_01507 4.6e-24 L transposition
NEGKCHNM_01508 4.8e-18 L PFAM Integrase catalytic
NEGKCHNM_01509 7.1e-34 L Transposase
NEGKCHNM_01510 1.6e-31 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
NEGKCHNM_01511 8.8e-67
NEGKCHNM_01512 1.5e-48
NEGKCHNM_01513 2.5e-24
NEGKCHNM_01514 1.4e-251 S Psort location CytoplasmicMembrane, score 9.99
NEGKCHNM_01515 6e-16 yccF S Inner membrane component domain
NEGKCHNM_01516 4.5e-151 V Abi-like protein
NEGKCHNM_01517 6.3e-55 yccF S Inner membrane component domain
NEGKCHNM_01518 0.0 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
NEGKCHNM_01519 6.6e-145 G Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01520 1.4e-162 G PFAM binding-protein-dependent transport systems inner membrane component
NEGKCHNM_01521 3.1e-98 G Bacterial extracellular solute-binding protein
NEGKCHNM_01522 3.3e-84 G Bacterial extracellular solute-binding protein
NEGKCHNM_01523 2.9e-182 K helix_turn _helix lactose operon repressor
NEGKCHNM_01524 5.9e-183 K Psort location Cytoplasmic, score
NEGKCHNM_01525 3e-270 G Bacterial extracellular solute-binding protein
NEGKCHNM_01526 7.2e-161 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01527 6.2e-121 P Binding-protein-dependent transport system inner membrane component
NEGKCHNM_01528 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NEGKCHNM_01529 4.8e-267 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NEGKCHNM_01531 4.9e-08 wcoI DM Psort location CytoplasmicMembrane, score
NEGKCHNM_01532 7.8e-88
NEGKCHNM_01533 7.3e-170 S G5
NEGKCHNM_01534 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
NEGKCHNM_01535 1.7e-113 F Domain of unknown function (DUF4916)
NEGKCHNM_01536 5.8e-160 mhpC I Alpha/beta hydrolase family
NEGKCHNM_01537 1.9e-208 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
NEGKCHNM_01538 1e-69 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NEGKCHNM_01539 2.1e-235 S Uncharacterized conserved protein (DUF2183)
NEGKCHNM_01540 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
NEGKCHNM_01541 8.4e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NEGKCHNM_01542 4.2e-44 J TM2 domain
NEGKCHNM_01543 3e-212 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
NEGKCHNM_01544 8e-134 glxR K helix_turn_helix, cAMP Regulatory protein
NEGKCHNM_01545 6.7e-70 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
NEGKCHNM_01546 2.8e-24 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
NEGKCHNM_01547 2.7e-294 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
NEGKCHNM_01548 3.9e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
NEGKCHNM_01549 4.4e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
NEGKCHNM_01550 3.4e-141 glpR K DeoR C terminal sensor domain
NEGKCHNM_01551 4e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
NEGKCHNM_01552 9e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
NEGKCHNM_01553 1.1e-23 lmrB EGP Major facilitator Superfamily
NEGKCHNM_01554 7.1e-43 gcvR T Belongs to the UPF0237 family
NEGKCHNM_01555 5.5e-253 S UPF0210 protein
NEGKCHNM_01556 2.5e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEGKCHNM_01557 1.6e-179 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
NEGKCHNM_01558 6.8e-100
NEGKCHNM_01559 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEGKCHNM_01560 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEGKCHNM_01561 3.8e-274 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEGKCHNM_01562 5.4e-101 T Forkhead associated domain
NEGKCHNM_01563 4.8e-104 B Belongs to the OprB family
NEGKCHNM_01564 3.8e-162 3.1.3.16 T Sigma factor PP2C-like phosphatases
NEGKCHNM_01565 7.3e-59 E Transglutaminase-like superfamily
NEGKCHNM_01566 1.9e-33 E Transglutaminase-like superfamily
NEGKCHNM_01567 1.1e-221 E Transglutaminase-like superfamily
NEGKCHNM_01568 4.1e-220 S Protein of unknown function DUF58
NEGKCHNM_01569 2.3e-190 S ATPase family associated with various cellular activities (AAA)
NEGKCHNM_01570 6.1e-26 S ATPase family associated with various cellular activities (AAA)
NEGKCHNM_01571 0.0 S Fibronectin type 3 domain
NEGKCHNM_01572 9.5e-264 KLT Protein tyrosine kinase
NEGKCHNM_01573 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
NEGKCHNM_01574 6.3e-254 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
NEGKCHNM_01575 6.5e-106 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
NEGKCHNM_01576 3.9e-151 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
NEGKCHNM_01577 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
NEGKCHNM_01578 2.5e-245 G Major Facilitator Superfamily
NEGKCHNM_01579 1.4e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEGKCHNM_01580 5.7e-38 csoR S Metal-sensitive transcriptional repressor
NEGKCHNM_01581 0.0 pacS 3.6.3.54 P E1-E2 ATPase
NEGKCHNM_01582 9e-153 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEGKCHNM_01583 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEGKCHNM_01585 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
NEGKCHNM_01586 1e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEGKCHNM_01587 1.2e-107 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEGKCHNM_01588 3.3e-272 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
NEGKCHNM_01589 5e-125 XK27_06785 V ABC transporter
NEGKCHNM_01590 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEGKCHNM_01591 2.1e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NEGKCHNM_01592 1.4e-139 S SdpI/YhfL protein family
NEGKCHNM_01593 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
NEGKCHNM_01594 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NEGKCHNM_01595 8.1e-218 yxjG_1 E Psort location Cytoplasmic, score 8.87
NEGKCHNM_01596 5.6e-91 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEGKCHNM_01597 8.8e-109 J Acetyltransferase (GNAT) domain
NEGKCHNM_01598 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NEGKCHNM_01600 2.1e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
NEGKCHNM_01601 5.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEGKCHNM_01602 6.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEGKCHNM_01603 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
NEGKCHNM_01604 7e-178 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
NEGKCHNM_01605 5.2e-278 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEGKCHNM_01606 6.4e-66 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
NEGKCHNM_01607 5.1e-148 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NEGKCHNM_01608 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
NEGKCHNM_01609 1.6e-157 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
NEGKCHNM_01610 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NEGKCHNM_01611 4.3e-17 sixA 3.6.1.55 T Phosphoglycerate mutase family
NEGKCHNM_01612 4.1e-64 sixA 3.6.1.55 T Phosphoglycerate mutase family
NEGKCHNM_01613 4.9e-128 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NEGKCHNM_01614 1.9e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
NEGKCHNM_01615 2.2e-248 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
NEGKCHNM_01616 2e-74
NEGKCHNM_01617 2.6e-307 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NEGKCHNM_01618 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
NEGKCHNM_01619 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
NEGKCHNM_01620 7.4e-234 F Psort location CytoplasmicMembrane, score 10.00
NEGKCHNM_01621 6.2e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
NEGKCHNM_01622 7.6e-288 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
NEGKCHNM_01623 5e-145 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
NEGKCHNM_01624 7.3e-233 hemN H Involved in the biosynthesis of porphyrin-containing compound
NEGKCHNM_01625 8.9e-209 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEGKCHNM_01626 9.2e-40 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEGKCHNM_01627 2.7e-73 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEGKCHNM_01628 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
NEGKCHNM_01629 3.1e-133 S UPF0126 domain
NEGKCHNM_01630 2.5e-227 ilvE 2.6.1.42 E Amino-transferase class IV
NEGKCHNM_01632 9.7e-58 K Acetyltransferase (GNAT) domain
NEGKCHNM_01633 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEGKCHNM_01634 7.2e-89 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEGKCHNM_01635 6.5e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NEGKCHNM_01636 3.8e-195 S alpha beta
NEGKCHNM_01637 1.3e-25 yhjX EGP Major facilitator Superfamily
NEGKCHNM_01638 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NEGKCHNM_01639 8.7e-153 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEGKCHNM_01640 1.3e-24 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEGKCHNM_01642 5.4e-225 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEGKCHNM_01643 1.1e-179 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEGKCHNM_01644 2.1e-73 nrdI F Probably involved in ribonucleotide reductase function
NEGKCHNM_01645 1.4e-39 nrdH O Glutaredoxin
NEGKCHNM_01646 7e-121 K Bacterial regulatory proteins, tetR family
NEGKCHNM_01647 7.6e-220 G Transmembrane secretion effector
NEGKCHNM_01648 1.2e-14 G Transmembrane secretion effector
NEGKCHNM_01650 2.7e-268 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_01651 3.5e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NEGKCHNM_01652 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
NEGKCHNM_01653 1.7e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
NEGKCHNM_01654 5.3e-240 fadD 6.2.1.3 I AMP-binding enzyme
NEGKCHNM_01655 1e-136 fadD 6.2.1.3 I AMP-binding enzyme
NEGKCHNM_01656 4.7e-97 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEGKCHNM_01657 1.1e-75 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEGKCHNM_01658 4.1e-251 corC S CBS domain
NEGKCHNM_01659 2.6e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEGKCHNM_01660 1.7e-207 phoH T PhoH-like protein
NEGKCHNM_01661 1.8e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
NEGKCHNM_01662 1e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEGKCHNM_01664 2.6e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
NEGKCHNM_01665 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NEGKCHNM_01666 1e-107 yitW S Iron-sulfur cluster assembly protein
NEGKCHNM_01667 3.4e-100 iscU C SUF system FeS assembly protein, NifU family
NEGKCHNM_01668 5.5e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEGKCHNM_01669 1e-142 sufC O FeS assembly ATPase SufC
NEGKCHNM_01670 1e-234 sufD O FeS assembly protein SufD
NEGKCHNM_01671 8.8e-78 sufB O FeS assembly protein SufB
NEGKCHNM_01672 4.6e-202 sufB O FeS assembly protein SufB
NEGKCHNM_01673 0.0 S L,D-transpeptidase catalytic domain
NEGKCHNM_01674 2.3e-147 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEGKCHNM_01675 1.4e-135 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEGKCHNM_01676 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
NEGKCHNM_01677 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NEGKCHNM_01678 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NEGKCHNM_01679 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEGKCHNM_01680 4.9e-50 3.4.23.43 S Type IV leader peptidase family
NEGKCHNM_01681 8.9e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NEGKCHNM_01682 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEGKCHNM_01683 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEGKCHNM_01684 2.5e-36
NEGKCHNM_01685 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
NEGKCHNM_01686 9.2e-59 pgm3 G Phosphoglycerate mutase family
NEGKCHNM_01687 8.5e-50 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NEGKCHNM_01688 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEGKCHNM_01689 4.9e-137 lolD V ABC transporter
NEGKCHNM_01690 4.8e-216 V FtsX-like permease family
NEGKCHNM_01691 1.7e-61 S Domain of unknown function (DUF4418)
NEGKCHNM_01692 0.0 pcrA 3.6.4.12 L DNA helicase
NEGKCHNM_01693 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEGKCHNM_01694 2.8e-244 pbuX F Permease family
NEGKCHNM_01695 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
NEGKCHNM_01696 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEGKCHNM_01697 2.7e-302 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NEGKCHNM_01698 4.3e-183 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NEGKCHNM_01699 9.8e-130 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NEGKCHNM_01700 2.7e-88 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
NEGKCHNM_01701 3.5e-78 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NEGKCHNM_01702 5.5e-211 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NEGKCHNM_01703 5.8e-76 yiaC K Acetyltransferase (GNAT) domain
NEGKCHNM_01704 2.2e-70 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
NEGKCHNM_01705 4.4e-255 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEGKCHNM_01707 2.3e-69 S MvaI/BcnI restriction endonuclease family
NEGKCHNM_01708 5.5e-124 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
NEGKCHNM_01710 9.3e-55
NEGKCHNM_01711 1.8e-33
NEGKCHNM_01713 2.7e-09 S Phage portal protein, SPP1 Gp6-like
NEGKCHNM_01714 1.2e-17 S Terminase
NEGKCHNM_01715 1.1e-71 XK26_04895
NEGKCHNM_01716 2.3e-19 V HNH nucleases
NEGKCHNM_01718 2.2e-210 ykiI
NEGKCHNM_01719 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NEGKCHNM_01720 2.1e-120 3.6.1.13 L NUDIX domain
NEGKCHNM_01721 5.9e-35 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
NEGKCHNM_01722 5.5e-118 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
NEGKCHNM_01723 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEGKCHNM_01724 4.7e-143 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEGKCHNM_01725 9.4e-101 pdtaR T Response regulator receiver domain protein
NEGKCHNM_01726 6.8e-164 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
NEGKCHNM_01728 4.3e-63
NEGKCHNM_01729 1.6e-95 M Peptidase family M23
NEGKCHNM_01730 2.7e-28 fadD1 6.2.1.3 I AMP-binding enzyme
NEGKCHNM_01731 2.4e-308 fadD1 6.2.1.3 I AMP-binding enzyme
NEGKCHNM_01732 3.1e-268 G ABC transporter substrate-binding protein
NEGKCHNM_01733 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
NEGKCHNM_01734 1.1e-209 guaB 1.1.1.205 F IMP dehydrogenase family protein
NEGKCHNM_01735 6.1e-108 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
NEGKCHNM_01736 1.3e-70 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEGKCHNM_01737 1.5e-189 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEGKCHNM_01738 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEGKCHNM_01739 2.5e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NEGKCHNM_01740 5.4e-116
NEGKCHNM_01742 1.8e-226 XK27_00240 K Fic/DOC family
NEGKCHNM_01743 7.9e-10
NEGKCHNM_01744 2.7e-70 pdxH S Pfam:Pyridox_oxidase
NEGKCHNM_01745 1.9e-300 M domain protein
NEGKCHNM_01746 1.1e-62 3.4.22.70 M Sortase family
NEGKCHNM_01747 1.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NEGKCHNM_01748 1.2e-147 corA P CorA-like Mg2+ transporter protein
NEGKCHNM_01749 1.1e-104 ET Bacterial periplasmic substrate-binding proteins
NEGKCHNM_01750 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NEGKCHNM_01751 7.1e-28 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
NEGKCHNM_01752 0.0 comE S Competence protein
NEGKCHNM_01753 6.5e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
NEGKCHNM_01754 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
NEGKCHNM_01755 1.3e-148 yeaZ 2.3.1.234 O Glycoprotease family
NEGKCHNM_01756 8.6e-85 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
NEGKCHNM_01757 9.9e-194 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEGKCHNM_01759 2.6e-119 yoaP E YoaP-like
NEGKCHNM_01760 7.8e-100 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEGKCHNM_01761 2.2e-72 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEGKCHNM_01762 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
NEGKCHNM_01763 6.7e-72 K MerR family regulatory protein
NEGKCHNM_01764 1.1e-197 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
NEGKCHNM_01765 2.4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
NEGKCHNM_01766 7.3e-194 yxjG_1 E Psort location Cytoplasmic, score 8.87
NEGKCHNM_01767 3.6e-76 S Psort location CytoplasmicMembrane, score
NEGKCHNM_01768 1e-182 cat P Cation efflux family
NEGKCHNM_01771 1.9e-108
NEGKCHNM_01772 1.1e-140
NEGKCHNM_01773 9.1e-144 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_01774 1.9e-272 pepC 3.4.22.40 E Peptidase C1-like family
NEGKCHNM_01775 3.3e-172 S IMP dehydrogenase activity
NEGKCHNM_01777 1.3e-298 ybiT S ABC transporter
NEGKCHNM_01778 3.3e-109 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
NEGKCHNM_01779 6.3e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NEGKCHNM_01781 9.8e-13
NEGKCHNM_01782 3.5e-272 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_01783 3.1e-139 S Domain of unknown function (DUF4194)
NEGKCHNM_01784 2.8e-111 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_01785 0.0 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_01786 6e-219 S Psort location Cytoplasmic, score 8.87
NEGKCHNM_01787 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEGKCHNM_01788 2.8e-51 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEGKCHNM_01789 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEGKCHNM_01790 2.1e-182 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
NEGKCHNM_01791 4e-170 rapZ S Displays ATPase and GTPase activities
NEGKCHNM_01792 1.3e-171 whiA K May be required for sporulation
NEGKCHNM_01793 1.9e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
NEGKCHNM_01794 1.6e-148 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEGKCHNM_01795 5.3e-32 secG U Preprotein translocase SecG subunit
NEGKCHNM_01796 3.3e-163 S Sucrose-6F-phosphate phosphohydrolase
NEGKCHNM_01797 1.5e-299 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
NEGKCHNM_01798 1.2e-08 pnuC H Nicotinamide mononucleotide transporter
NEGKCHNM_01799 7.8e-107 pnuC H Nicotinamide mononucleotide transporter
NEGKCHNM_01800 8.3e-41 nadR H ATPase kinase involved in NAD metabolism
NEGKCHNM_01801 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NEGKCHNM_01802 1.3e-102 tkt 2.2.1.1 H Belongs to the transketolase family
NEGKCHNM_01803 1.6e-232 tkt 2.2.1.1 H Belongs to the transketolase family
NEGKCHNM_01804 3e-196 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEGKCHNM_01805 2.4e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEGKCHNM_01806 5.1e-158 G Fructosamine kinase
NEGKCHNM_01807 6.9e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NEGKCHNM_01808 6.2e-156 S PAC2 family
NEGKCHNM_01815 1.4e-08
NEGKCHNM_01816 5.4e-36
NEGKCHNM_01817 1.1e-75 garA T Inner membrane component of T3SS, cytoplasmic domain
NEGKCHNM_01818 1.2e-52 K helix_turn_helix, mercury resistance
NEGKCHNM_01819 1.6e-32 K helix_turn_helix, mercury resistance
NEGKCHNM_01820 4.6e-61
NEGKCHNM_01821 3e-141 pgp 3.1.3.18 S HAD-hyrolase-like
NEGKCHNM_01822 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
NEGKCHNM_01823 2.9e-136 helY L DEAD DEAH box helicase
NEGKCHNM_01824 0.0 helY L DEAD DEAH box helicase
NEGKCHNM_01825 2.1e-54
NEGKCHNM_01826 0.0 pafB K WYL domain
NEGKCHNM_01827 1.4e-264 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
NEGKCHNM_01829 5.5e-48
NEGKCHNM_01830 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
NEGKCHNM_01831 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NEGKCHNM_01832 4.9e-160 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NEGKCHNM_01833 8.2e-34
NEGKCHNM_01834 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NEGKCHNM_01835 1.7e-88
NEGKCHNM_01836 1.6e-133
NEGKCHNM_01837 2.6e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NEGKCHNM_01838 2.2e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NEGKCHNM_01839 3e-27 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEGKCHNM_01840 4.6e-49 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEGKCHNM_01841 1.2e-49 yajC U Preprotein translocase subunit
NEGKCHNM_01842 2.8e-199 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEGKCHNM_01843 1e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEGKCHNM_01844 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NEGKCHNM_01845 5.2e-128 yebC K transcriptional regulatory protein
NEGKCHNM_01846 1.8e-100 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
NEGKCHNM_01847 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEGKCHNM_01848 6.5e-140 S Bacterial protein of unknown function (DUF881)
NEGKCHNM_01849 4.2e-45 sbp S Protein of unknown function (DUF1290)
NEGKCHNM_01850 1.4e-170 S Bacterial protein of unknown function (DUF881)
NEGKCHNM_01851 1.4e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEGKCHNM_01852 3.3e-155 hisG 2.4.2.17 F ATP phosphoribosyltransferase
NEGKCHNM_01853 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
NEGKCHNM_01854 3.8e-32 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
NEGKCHNM_01855 4.6e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEGKCHNM_01856 1.1e-161 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEGKCHNM_01857 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEGKCHNM_01858 7.8e-23 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEGKCHNM_01859 4.6e-296 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NEGKCHNM_01860 1.9e-71 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NEGKCHNM_01861 8.8e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEGKCHNM_01862 1.2e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NEGKCHNM_01863 6.1e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
NEGKCHNM_01864 7.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEGKCHNM_01865 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NEGKCHNM_01867 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEGKCHNM_01868 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
NEGKCHNM_01869 1.1e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEGKCHNM_01870 5.1e-177 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
NEGKCHNM_01871 6.1e-148 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
NEGKCHNM_01872 1e-119
NEGKCHNM_01873 6.2e-157 mltE2 M Bacteriophage peptidoglycan hydrolase
NEGKCHNM_01876 3.7e-72
NEGKCHNM_01877 1.6e-18
NEGKCHNM_01879 7e-30 yuxJ EGP Major facilitator Superfamily
NEGKCHNM_01880 1.5e-137 EGP Major facilitator Superfamily
NEGKCHNM_01882 5.6e-59
NEGKCHNM_01883 2.6e-300 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
NEGKCHNM_01884 1e-10
NEGKCHNM_01885 2e-67
NEGKCHNM_01886 2.6e-258 S AAA domain
NEGKCHNM_01887 1.5e-261 lytC 3.2.1.17, 3.2.1.96, 3.2.1.97 GH101 M Glycosyl hydrolases family 25
NEGKCHNM_01888 5e-16 3.2.1.97 GH101 S CHAP domain
NEGKCHNM_01889 7.2e-175 ykoT 2.4.1.83 GT2 M Glycosyl transferase family 2
NEGKCHNM_01890 1.1e-300
NEGKCHNM_01891 3.5e-18 3.1.1.5, 3.2.1.97 GH101 E GDSL-like Lipase/Acylhydrolase family
NEGKCHNM_01892 1.5e-09 lytC 3.2.1.17, 3.2.1.96, 3.2.1.97 GH101 M Glycosyl hydrolases family 25
NEGKCHNM_01893 2.3e-126 3.1.1.5, 3.2.1.97 GH101 E GDSL-like Lipase/Acylhydrolase family
NEGKCHNM_01894 2.5e-200 cps3I G Psort location CytoplasmicMembrane, score 9.99
NEGKCHNM_01895 0.0 2.4.1.288 GT2 S Glycosyltransferase like family 2
NEGKCHNM_01896 3.7e-210 M LicD family
NEGKCHNM_01897 7.9e-137 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NEGKCHNM_01898 3.7e-180 GM GDP-mannose 4,6 dehydratase
NEGKCHNM_01899 4.2e-147 rgpC U Transport permease protein
NEGKCHNM_01900 1.1e-239 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
NEGKCHNM_01901 1.6e-221 3.2.1.97 GH101 S Psort location Extracellular, score
NEGKCHNM_01902 7.6e-15 3.2.1.97 GH101 S Psort location Extracellular, score
NEGKCHNM_01903 7.4e-207 S Predicted membrane protein (DUF2142)
NEGKCHNM_01904 3.8e-101 3.2.1.97 GH101 M Cell wall-binding repeat protein
NEGKCHNM_01905 0.0 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
NEGKCHNM_01906 5e-234 glf 5.4.99.9 M UDP-galactopyranose mutase
NEGKCHNM_01907 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
NEGKCHNM_01908 2.5e-33 S Domain of unknown function (DUF4143)
NEGKCHNM_01909 2.7e-95 L Resolvase, N terminal domain
NEGKCHNM_01910 8.2e-157 L Helix-turn-helix domain
NEGKCHNM_01911 1.2e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEGKCHNM_01912 6.4e-24 S Addiction module toxin, RelE StbE family
NEGKCHNM_01913 1.1e-17 relB L RelB antitoxin
NEGKCHNM_01914 1.2e-61
NEGKCHNM_01915 2.8e-196 K helix_turn _helix lactose operon repressor
NEGKCHNM_01916 5.5e-167 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NEGKCHNM_01917 1.3e-22 EGP Major Facilitator Superfamily
NEGKCHNM_01918 9.1e-35 EGP Major Facilitator Superfamily
NEGKCHNM_01919 7.4e-161 EGP Major Facilitator Superfamily
NEGKCHNM_01920 5.7e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEGKCHNM_01921 5.4e-107 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEGKCHNM_01922 3e-57 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEGKCHNM_01923 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NEGKCHNM_01924 9.7e-70 ssb1 L Single-stranded DNA-binding protein
NEGKCHNM_01925 1.8e-27 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEGKCHNM_01926 1.7e-70 rplI J Binds to the 23S rRNA
NEGKCHNM_01928 1.4e-125 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NEGKCHNM_01929 3.7e-09 M Protein of unknown function (DUF3152)
NEGKCHNM_01930 3.3e-54 M Protein of unknown function (DUF3152)
NEGKCHNM_01931 9.1e-203 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
NEGKCHNM_01932 2.1e-67
NEGKCHNM_01933 1.4e-147 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NEGKCHNM_01934 1.4e-164 fahA Q Fumarylacetoacetate (FAA) hydrolase family
NEGKCHNM_01935 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEGKCHNM_01936 8e-136 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
NEGKCHNM_01937 5.7e-170 rmuC S RmuC family
NEGKCHNM_01938 9.1e-105 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEGKCHNM_01939 6.9e-133 spoU 2.1.1.185 J RNA methyltransferase TrmH family
NEGKCHNM_01940 8.9e-133 K Psort location Cytoplasmic, score
NEGKCHNM_01941 1.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEGKCHNM_01942 1.1e-201 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEGKCHNM_01943 1.4e-62 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEGKCHNM_01944 2.2e-106 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEGKCHNM_01945 2.8e-154 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEGKCHNM_01946 2e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
NEGKCHNM_01947 2.1e-51 S Protein of unknown function (DUF2469)
NEGKCHNM_01948 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
NEGKCHNM_01949 5.1e-245 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEGKCHNM_01950 1.3e-79 K helix_turn_helix ASNC type
NEGKCHNM_01951 1.8e-69 tyrA 5.4.99.5 E Chorismate mutase type II
NEGKCHNM_01952 0.0 S domain protein
NEGKCHNM_01953 1.8e-22 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEGKCHNM_01954 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEGKCHNM_01955 5.3e-113 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEGKCHNM_01956 1e-287 E Bacterial extracellular solute-binding proteins, family 5 Middle
NEGKCHNM_01957 9.4e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEGKCHNM_01958 8.4e-134 KT Transcriptional regulatory protein, C terminal
NEGKCHNM_01959 6.4e-134
NEGKCHNM_01960 9.4e-98 mntP P Probably functions as a manganese efflux pump
NEGKCHNM_01961 3.4e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NEGKCHNM_01962 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
NEGKCHNM_01964 2.1e-174 M LPXTG-motif cell wall anchor domain protein
NEGKCHNM_01965 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
NEGKCHNM_01966 2.9e-191 yfdV S Membrane transport protein
NEGKCHNM_01967 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NEGKCHNM_01969 5.4e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NEGKCHNM_01970 8.2e-16 atpB C it plays a direct role in the translocation of protons across the membrane
NEGKCHNM_01971 1.3e-102 atpB C it plays a direct role in the translocation of protons across the membrane
NEGKCHNM_01972 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEGKCHNM_01973 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEGKCHNM_01974 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEGKCHNM_01975 4.2e-308 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEGKCHNM_01976 3.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEGKCHNM_01977 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEGKCHNM_01978 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NEGKCHNM_01979 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NEGKCHNM_01980 1.1e-149 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
NEGKCHNM_01981 3.3e-109
NEGKCHNM_01982 3.3e-178
NEGKCHNM_01983 9.3e-170 trxA2 O Tetratricopeptide repeat
NEGKCHNM_01984 1.8e-121 cyaA 4.6.1.1 S CYTH
NEGKCHNM_01986 2.8e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
NEGKCHNM_01987 4.8e-271 mmuP E amino acid
NEGKCHNM_01988 1.5e-208 argS 6.1.1.19 J Arginyl-tRNA synthetase
NEGKCHNM_01989 6.6e-122 argS 6.1.1.19 J Arginyl-tRNA synthetase
NEGKCHNM_01990 2.5e-58 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEGKCHNM_01991 1.7e-207 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEGKCHNM_01992 9e-212 hom 1.1.1.3 E Homoserine dehydrogenase
NEGKCHNM_01994 8.5e-69 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEGKCHNM_01995 5.3e-92 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NEGKCHNM_01996 2e-285 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
NEGKCHNM_01997 3.1e-209 K helix_turn _helix lactose operon repressor
NEGKCHNM_01998 2.3e-117 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
NEGKCHNM_01999 1.1e-152 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
NEGKCHNM_02000 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
NEGKCHNM_02001 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NEGKCHNM_02002 0.0 fadD 6.2.1.3 I AMP-binding enzyme
NEGKCHNM_02003 0.0 cydD V ABC transporter transmembrane region
NEGKCHNM_02004 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NEGKCHNM_02005 3.3e-127 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NEGKCHNM_02006 9.1e-240 G Bacterial extracellular solute-binding protein
NEGKCHNM_02007 1.4e-244 hsdM 2.1.1.72 V HsdM N-terminal domain
NEGKCHNM_02008 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NEGKCHNM_02009 5.1e-37 pcrA1 3.6.4.12 F DNA helicase
NEGKCHNM_02010 3.1e-100 E Binding-protein-dependent transport system inner membrane component
NEGKCHNM_02011 1.4e-121 tcyA ET Bacterial periplasmic substrate-binding proteins
NEGKCHNM_02012 3.2e-115 3.6.3.21 E ATPases associated with a variety of cellular activities
NEGKCHNM_02013 7.2e-196 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NEGKCHNM_02015 2.9e-18 relB L RelB antitoxin
NEGKCHNM_02017 5.6e-305 pyk 2.7.1.40 G Pyruvate kinase
NEGKCHNM_02018 8.8e-176 terC P Integral membrane protein, TerC family
NEGKCHNM_02019 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEGKCHNM_02020 9.1e-116 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEGKCHNM_02021 5.3e-168 rpsA J Ribosomal protein S1
NEGKCHNM_02022 1.9e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEGKCHNM_02023 3.3e-176 P Zinc-uptake complex component A periplasmic
NEGKCHNM_02024 2e-160 znuC P ATPases associated with a variety of cellular activities
NEGKCHNM_02025 3.9e-140 znuB U ABC 3 transport family
NEGKCHNM_02026 7.8e-88 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NEGKCHNM_02027 3e-102 carD K CarD-like/TRCF domain
NEGKCHNM_02028 1.6e-146 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEGKCHNM_02029 5.5e-307 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NEGKCHNM_02030 1.1e-187 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEGKCHNM_02031 2.3e-57 ctsW S Phosphoribosyl transferase domain
NEGKCHNM_02032 5.7e-62 ctsW S Phosphoribosyl transferase domain
NEGKCHNM_02033 1.1e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
NEGKCHNM_02034 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
NEGKCHNM_02035 3.3e-222
NEGKCHNM_02036 0.0 S Glycosyl transferase, family 2
NEGKCHNM_02037 1e-145 S Glycosyl transferase, family 2
NEGKCHNM_02038 4.1e-31 S Glycosyl transferase, family 2
NEGKCHNM_02039 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NEGKCHNM_02040 4.8e-199 K Cell envelope-related transcriptional attenuator domain
NEGKCHNM_02042 1.1e-168 K Cell envelope-related transcriptional attenuator domain
NEGKCHNM_02043 0.0 D FtsK/SpoIIIE family
NEGKCHNM_02044 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
NEGKCHNM_02045 3.4e-280 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEGKCHNM_02046 2.7e-144 yplQ S Haemolysin-III related
NEGKCHNM_02047 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEGKCHNM_02048 3.6e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
NEGKCHNM_02049 4.6e-120 sdaA 4.3.1.17 E Serine dehydratase alpha chain
NEGKCHNM_02050 4.4e-73 sdaA 4.3.1.17 E Serine dehydratase alpha chain
NEGKCHNM_02051 1.3e-91
NEGKCHNM_02053 5e-72 P Major Facilitator Superfamily
NEGKCHNM_02055 2.2e-182 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
NEGKCHNM_02056 2e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
NEGKCHNM_02057 6.5e-59 divIC D Septum formation initiator
NEGKCHNM_02058 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEGKCHNM_02059 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEGKCHNM_02060 4.2e-159 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEGKCHNM_02061 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEGKCHNM_02062 1.1e-92 2.3.1.183 M Acetyltransferase (GNAT) domain
NEGKCHNM_02063 5.2e-136 S Uncharacterised protein family (UPF0182)
NEGKCHNM_02064 2.7e-14 S Uncharacterised protein family (UPF0182)
NEGKCHNM_02065 3.2e-292 S Uncharacterised protein family (UPF0182)
NEGKCHNM_02066 1.1e-73 S Uncharacterised protein family (UPF0182)
NEGKCHNM_02067 9e-178 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
NEGKCHNM_02068 6.2e-40 ybdD S Selenoprotein, putative
NEGKCHNM_02069 4.9e-61 cstA T 5TM C-terminal transporter carbon starvation CstA
NEGKCHNM_02070 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
NEGKCHNM_02071 3.2e-53 azlD E Branched-chain amino acid transport protein (AzlD)
NEGKCHNM_02072 5.6e-89 azlC E AzlC protein
NEGKCHNM_02073 1.7e-13 azlC E AzlC protein
NEGKCHNM_02074 7.1e-16 azlC E AzlC protein
NEGKCHNM_02075 1.1e-86 M Protein of unknown function (DUF3737)
NEGKCHNM_02076 1.8e-81 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEGKCHNM_02077 9.9e-146 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
NEGKCHNM_02078 5e-176 opcA G Glucose-6-phosphate dehydrogenase subunit
NEGKCHNM_02079 1.8e-303 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEGKCHNM_02080 1.6e-235 patB 4.4.1.8 E Aminotransferase, class I II
NEGKCHNM_02081 2.6e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEGKCHNM_02082 0.0 lysX S Uncharacterised conserved protein (DUF2156)
NEGKCHNM_02083 2.3e-246 S Putative esterase
NEGKCHNM_02084 2.7e-135 ybbL V ATPases associated with a variety of cellular activities
NEGKCHNM_02085 9.4e-14 ybbM V Uncharacterised protein family (UPF0014)
NEGKCHNM_02086 3.7e-103 ybbM V Uncharacterised protein family (UPF0014)
NEGKCHNM_02087 4.4e-278 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
NEGKCHNM_02088 6e-126 S Enoyl-(Acyl carrier protein) reductase
NEGKCHNM_02089 2.9e-227 rutG F Permease family
NEGKCHNM_02090 2e-157 3.1.3.73 G Phosphoglycerate mutase family
NEGKCHNM_02091 7e-141 K helix_turn_helix, arabinose operon control protein
NEGKCHNM_02092 1.4e-137 S Sulfite exporter TauE/SafE
NEGKCHNM_02093 7.3e-93 S ECF transporter, substrate-specific component
NEGKCHNM_02094 1.4e-112 2.7.1.48 F uridine kinase
NEGKCHNM_02095 2.5e-172 korD 1.2.7.3 C Domain of unknown function (DUF362)
NEGKCHNM_02096 8.7e-224 C Na H antiporter family protein
NEGKCHNM_02097 3.4e-181 MA20_14895 S Conserved hypothetical protein 698
NEGKCHNM_02098 7e-118
NEGKCHNM_02099 4.9e-16 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NEGKCHNM_02100 3.6e-88 cysB 4.2.1.22 EGP Major facilitator Superfamily
NEGKCHNM_02101 8.2e-250 cysB 4.2.1.22 EGP Major facilitator Superfamily
NEGKCHNM_02102 5e-11
NEGKCHNM_02103 3.6e-58 yccF S Inner membrane component domain
NEGKCHNM_02104 1.2e-118 K Bacterial regulatory proteins, tetR family
NEGKCHNM_02105 3e-213 G Transmembrane secretion effector
NEGKCHNM_02106 1.6e-16 K addiction module antidote protein HigA
NEGKCHNM_02107 4e-192 S HipA-like C-terminal domain
NEGKCHNM_02108 4.5e-19 S HipA-like C-terminal domain
NEGKCHNM_02109 6.7e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEGKCHNM_02110 7.7e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEGKCHNM_02111 3.3e-266 pip 3.4.11.5 S alpha/beta hydrolase fold
NEGKCHNM_02112 0.0 tcsS2 T Histidine kinase
NEGKCHNM_02113 1.4e-128 K helix_turn_helix, Lux Regulon
NEGKCHNM_02114 0.0 MV MacB-like periplasmic core domain
NEGKCHNM_02115 8.8e-41 V ABC transporter, ATP-binding protein
NEGKCHNM_02116 4.7e-89 V ABC transporter, ATP-binding protein
NEGKCHNM_02117 8.2e-193 K helix_turn_helix ASNC type
NEGKCHNM_02118 9.2e-22 P Cobalt transport protein
NEGKCHNM_02119 2.4e-95 P Cobalt transport protein
NEGKCHNM_02120 1.4e-110 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
NEGKCHNM_02121 3.1e-50 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
NEGKCHNM_02122 3e-94 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
NEGKCHNM_02123 4.3e-95 XK27_01265 S ECF-type riboflavin transporter, S component
NEGKCHNM_02124 1.8e-27 metY 2.5.1.49 E Aminotransferase class-V
NEGKCHNM_02125 3.7e-186 metY 2.5.1.49 E Aminotransferase class-V
NEGKCHNM_02126 5.4e-92 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NEGKCHNM_02127 1.9e-59 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NEGKCHNM_02128 3.1e-83 yraN L Belongs to the UPF0102 family
NEGKCHNM_02129 6.3e-285 comM O Magnesium chelatase, subunit ChlI C-terminal
NEGKCHNM_02130 2.7e-255 dprA 5.99.1.2 LU DNA recombination-mediator protein A
NEGKCHNM_02131 5.1e-105 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
NEGKCHNM_02132 7.8e-41 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
NEGKCHNM_02133 6e-180 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
NEGKCHNM_02134 2e-177 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
NEGKCHNM_02135 2.4e-116 safC S O-methyltransferase
NEGKCHNM_02136 3.9e-246 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)