ORF_ID e_value Gene_name EC_number CAZy COGs Description
MGEDCBFO_00001 2.2e-195 L Integrase core domain
MGEDCBFO_00002 7.8e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
MGEDCBFO_00003 4.8e-199 gluD E Binding-protein-dependent transport system inner membrane component
MGEDCBFO_00004 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
MGEDCBFO_00005 9.5e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
MGEDCBFO_00006 3.6e-140 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
MGEDCBFO_00007 8.2e-93 S Aminoacyl-tRNA editing domain
MGEDCBFO_00008 3.3e-81 K helix_turn_helix, Lux Regulon
MGEDCBFO_00009 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MGEDCBFO_00010 8.7e-262 hisS 6.1.1.21 J Histidyl-tRNA synthetase
MGEDCBFO_00011 5.1e-217 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
MGEDCBFO_00012 5e-56 2.7.13.3 T Histidine kinase
MGEDCBFO_00015 0.0 clpC O ATPase family associated with various cellular activities (AAA)
MGEDCBFO_00016 4.7e-185 uspA T Belongs to the universal stress protein A family
MGEDCBFO_00017 3.2e-203 S Protein of unknown function (DUF3027)
MGEDCBFO_00018 1e-66 cspB K 'Cold-shock' DNA-binding domain
MGEDCBFO_00019 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MGEDCBFO_00020 1.6e-134 KT Response regulator receiver domain protein
MGEDCBFO_00021 4.9e-162
MGEDCBFO_00022 1.7e-10 S Proteins of 100 residues with WXG
MGEDCBFO_00023 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MGEDCBFO_00024 8.3e-44 cspA K 'Cold-shock' DNA-binding domain
MGEDCBFO_00025 7.6e-71 S LytR cell envelope-related transcriptional attenuator
MGEDCBFO_00026 1.1e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MGEDCBFO_00027 2.3e-196 moxR S ATPase family associated with various cellular activities (AAA)
MGEDCBFO_00028 7.2e-178 S Protein of unknown function DUF58
MGEDCBFO_00029 6.4e-94
MGEDCBFO_00030 4.4e-189 S von Willebrand factor (vWF) type A domain
MGEDCBFO_00031 1.4e-147 S von Willebrand factor (vWF) type A domain
MGEDCBFO_00032 2.7e-74
MGEDCBFO_00034 2.9e-290 S PGAP1-like protein
MGEDCBFO_00035 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
MGEDCBFO_00036 0.0 S Lysylphosphatidylglycerol synthase TM region
MGEDCBFO_00037 8.1e-42 hup L Belongs to the bacterial histone-like protein family
MGEDCBFO_00038 2.2e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MGEDCBFO_00039 9.2e-11 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MGEDCBFO_00040 2.2e-156 hisN 3.1.3.25 G Inositol monophosphatase family
MGEDCBFO_00041 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
MGEDCBFO_00042 0.0 arc O AAA ATPase forming ring-shaped complexes
MGEDCBFO_00043 1.6e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
MGEDCBFO_00044 5.6e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MGEDCBFO_00045 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MGEDCBFO_00046 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MGEDCBFO_00047 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MGEDCBFO_00048 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MGEDCBFO_00049 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
MGEDCBFO_00050 1.1e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MGEDCBFO_00052 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MGEDCBFO_00053 0.0 ctpE P E1-E2 ATPase
MGEDCBFO_00054 2e-109
MGEDCBFO_00055 6.5e-248 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MGEDCBFO_00056 3.7e-129 S Protein of unknown function (DUF3159)
MGEDCBFO_00057 2.1e-138 S Protein of unknown function (DUF3710)
MGEDCBFO_00058 1.8e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
MGEDCBFO_00059 5.2e-262 pepC 3.4.22.40 E Peptidase C1-like family
MGEDCBFO_00060 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
MGEDCBFO_00061 0.0 oppD P Belongs to the ABC transporter superfamily
MGEDCBFO_00062 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
MGEDCBFO_00063 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
MGEDCBFO_00064 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MGEDCBFO_00065 7.3e-42
MGEDCBFO_00066 1.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
MGEDCBFO_00067 5.5e-197 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
MGEDCBFO_00068 5.5e-92
MGEDCBFO_00069 0.0 typA T Elongation factor G C-terminus
MGEDCBFO_00070 1.4e-237 iscS1 2.8.1.7 E Aminotransferase class-V
MGEDCBFO_00071 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
MGEDCBFO_00072 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MGEDCBFO_00073 9.8e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MGEDCBFO_00074 1.1e-149 nrtR 3.6.1.55 F NUDIX hydrolase
MGEDCBFO_00075 2.5e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MGEDCBFO_00076 3.2e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MGEDCBFO_00077 7e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MGEDCBFO_00078 2.9e-179 xerD D recombinase XerD
MGEDCBFO_00079 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MGEDCBFO_00080 2.1e-25 rpmI J Ribosomal protein L35
MGEDCBFO_00081 2.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MGEDCBFO_00082 1.9e-07 S Spermine/spermidine synthase domain
MGEDCBFO_00083 8e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
MGEDCBFO_00084 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MGEDCBFO_00085 2.4e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MGEDCBFO_00087 2e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MGEDCBFO_00088 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
MGEDCBFO_00089 2e-64
MGEDCBFO_00090 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
MGEDCBFO_00091 3e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MGEDCBFO_00092 5.7e-191 V Acetyltransferase (GNAT) domain
MGEDCBFO_00093 6.4e-229 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
MGEDCBFO_00094 2.8e-243 yxbA 6.3.1.12 S ATP-grasp
MGEDCBFO_00095 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
MGEDCBFO_00096 0.0 smc D Required for chromosome condensation and partitioning
MGEDCBFO_00097 8e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
MGEDCBFO_00099 9.6e-97 3.6.1.55 F NUDIX domain
MGEDCBFO_00100 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
MGEDCBFO_00101 0.0 P Belongs to the ABC transporter superfamily
MGEDCBFO_00102 1.9e-190 dppC EP Binding-protein-dependent transport system inner membrane component
MGEDCBFO_00103 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
MGEDCBFO_00104 3.7e-304 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
MGEDCBFO_00105 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
MGEDCBFO_00106 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MGEDCBFO_00107 7e-217 GK ROK family
MGEDCBFO_00108 3.4e-132 cutC P Participates in the control of copper homeostasis
MGEDCBFO_00109 1.3e-224 GK ROK family
MGEDCBFO_00110 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
MGEDCBFO_00111 4.4e-236 G Major Facilitator Superfamily
MGEDCBFO_00112 6.6e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MGEDCBFO_00114 1.3e-37
MGEDCBFO_00115 3.9e-160 ftsQ 6.3.2.4 D Cell division protein FtsQ
MGEDCBFO_00116 6.1e-296 murC 6.3.2.8 M Belongs to the MurCDEF family
MGEDCBFO_00117 6.5e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MGEDCBFO_00118 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
MGEDCBFO_00119 1.2e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MGEDCBFO_00120 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MGEDCBFO_00121 2.3e-284 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MGEDCBFO_00122 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MGEDCBFO_00123 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
MGEDCBFO_00124 2.5e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MGEDCBFO_00125 3.1e-193 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MGEDCBFO_00126 1.3e-90 mraZ K Belongs to the MraZ family
MGEDCBFO_00127 0.0 L DNA helicase
MGEDCBFO_00128 3.2e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MGEDCBFO_00129 1.1e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MGEDCBFO_00130 1.5e-43 M Lysin motif
MGEDCBFO_00131 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MGEDCBFO_00132 1.2e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MGEDCBFO_00133 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
MGEDCBFO_00134 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MGEDCBFO_00135 2.6e-169
MGEDCBFO_00136 4.1e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
MGEDCBFO_00137 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
MGEDCBFO_00138 1.3e-172 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MGEDCBFO_00139 1e-60 EGP Major facilitator Superfamily
MGEDCBFO_00140 3.2e-245 S Domain of unknown function (DUF5067)
MGEDCBFO_00141 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
MGEDCBFO_00142 3.5e-282 S Uncharacterized protein conserved in bacteria (DUF2252)
MGEDCBFO_00143 1.2e-129 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
MGEDCBFO_00144 1.1e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MGEDCBFO_00145 5.9e-113
MGEDCBFO_00146 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
MGEDCBFO_00147 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MGEDCBFO_00148 1.1e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MGEDCBFO_00149 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MGEDCBFO_00150 7.8e-08 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MGEDCBFO_00152 1.2e-76 yneG S Domain of unknown function (DUF4186)
MGEDCBFO_00153 6.4e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
MGEDCBFO_00154 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
MGEDCBFO_00155 3.4e-202 K WYL domain
MGEDCBFO_00157 0.0 4.2.1.53 S MCRA family
MGEDCBFO_00158 1.6e-46 yhbY J CRS1_YhbY
MGEDCBFO_00159 7.6e-106 S zinc-ribbon domain
MGEDCBFO_00160 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
MGEDCBFO_00161 4.5e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MGEDCBFO_00162 6.5e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MGEDCBFO_00163 1.5e-191 ywqG S Domain of unknown function (DUF1963)
MGEDCBFO_00164 5.3e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MGEDCBFO_00165 3.6e-140 recO L Involved in DNA repair and RecF pathway recombination
MGEDCBFO_00166 1.2e-291 I acetylesterase activity
MGEDCBFO_00167 6.1e-236 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MGEDCBFO_00168 1.5e-222 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MGEDCBFO_00169 1.5e-201 2.7.11.1 NU Tfp pilus assembly protein FimV
MGEDCBFO_00171 8.7e-24
MGEDCBFO_00172 5.7e-19
MGEDCBFO_00173 3.9e-144 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
MGEDCBFO_00174 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MGEDCBFO_00175 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
MGEDCBFO_00176 9.2e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
MGEDCBFO_00177 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
MGEDCBFO_00178 1.1e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MGEDCBFO_00179 3.7e-137 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MGEDCBFO_00180 6e-63
MGEDCBFO_00182 2e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MGEDCBFO_00183 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MGEDCBFO_00184 9.7e-90 3.1.21.3 V DivIVA protein
MGEDCBFO_00185 2.1e-42 yggT S YGGT family
MGEDCBFO_00186 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MGEDCBFO_00187 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MGEDCBFO_00188 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MGEDCBFO_00189 7.9e-301 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MGEDCBFO_00190 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
MGEDCBFO_00191 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MGEDCBFO_00192 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MGEDCBFO_00193 1.3e-84
MGEDCBFO_00194 6.9e-231 O AAA domain (Cdc48 subfamily)
MGEDCBFO_00195 5.4e-164 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MGEDCBFO_00196 4e-60 S Thiamine-binding protein
MGEDCBFO_00197 2.6e-194 K helix_turn _helix lactose operon repressor
MGEDCBFO_00198 5.7e-47 S Protein of unknown function (DUF3052)
MGEDCBFO_00199 1.7e-151 lon T Belongs to the peptidase S16 family
MGEDCBFO_00200 6.6e-279 S Zincin-like metallopeptidase
MGEDCBFO_00201 9.6e-283 uvrD2 3.6.4.12 L DNA helicase
MGEDCBFO_00202 2.7e-237 mphA S Aminoglycoside phosphotransferase
MGEDCBFO_00203 6.1e-32 S Protein of unknown function (DUF3107)
MGEDCBFO_00204 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
MGEDCBFO_00205 7.6e-115 S Vitamin K epoxide reductase
MGEDCBFO_00206 1.5e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MGEDCBFO_00207 1.1e-152 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MGEDCBFO_00208 1.8e-168 S Patatin-like phospholipase
MGEDCBFO_00209 0.0 V ABC transporter transmembrane region
MGEDCBFO_00210 0.0 V ABC transporter, ATP-binding protein
MGEDCBFO_00211 2.9e-88 K MarR family
MGEDCBFO_00212 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
MGEDCBFO_00213 2.2e-260 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
MGEDCBFO_00214 1.2e-166
MGEDCBFO_00215 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
MGEDCBFO_00217 4.3e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MGEDCBFO_00218 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
MGEDCBFO_00219 1.6e-271 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MGEDCBFO_00220 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MGEDCBFO_00221 5.6e-203 S Endonuclease/Exonuclease/phosphatase family
MGEDCBFO_00223 3.1e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MGEDCBFO_00224 1.2e-255 cdr OP Sulfurtransferase TusA
MGEDCBFO_00225 2.6e-149 moeB 2.7.7.80 H ThiF family
MGEDCBFO_00226 3.5e-132 tmp1 S Domain of unknown function (DUF4391)
MGEDCBFO_00227 2.3e-37 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MGEDCBFO_00228 2.9e-229 aspB E Aminotransferase class-V
MGEDCBFO_00229 2.4e-105 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MGEDCBFO_00230 1.4e-270 S zinc finger
MGEDCBFO_00231 1.2e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MGEDCBFO_00232 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MGEDCBFO_00233 2.1e-291 O Subtilase family
MGEDCBFO_00234 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
MGEDCBFO_00235 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MGEDCBFO_00236 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MGEDCBFO_00237 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MGEDCBFO_00238 1.4e-59 L Transposase
MGEDCBFO_00239 6.4e-24 relB L RelB antitoxin
MGEDCBFO_00240 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MGEDCBFO_00241 2.9e-66 gsiA P ATPase activity
MGEDCBFO_00242 1.3e-257 G Major Facilitator Superfamily
MGEDCBFO_00243 7.3e-158 K -acetyltransferase
MGEDCBFO_00244 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
MGEDCBFO_00245 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
MGEDCBFO_00246 1.8e-267 KLT Protein tyrosine kinase
MGEDCBFO_00247 0.0 S Fibronectin type 3 domain
MGEDCBFO_00248 1.8e-232 S ATPase family associated with various cellular activities (AAA)
MGEDCBFO_00249 1.7e-230 S Protein of unknown function DUF58
MGEDCBFO_00250 0.0 E Transglutaminase-like superfamily
MGEDCBFO_00251 2e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
MGEDCBFO_00252 2e-66 B Belongs to the OprB family
MGEDCBFO_00253 1.3e-96 T Forkhead associated domain
MGEDCBFO_00254 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MGEDCBFO_00255 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MGEDCBFO_00256 2.8e-101
MGEDCBFO_00257 3.9e-184 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
MGEDCBFO_00258 1.1e-35 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
MGEDCBFO_00259 5.9e-52 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
MGEDCBFO_00260 1.5e-07 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
MGEDCBFO_00261 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MGEDCBFO_00263 9.4e-124
MGEDCBFO_00265 1.2e-252 S UPF0210 protein
MGEDCBFO_00266 4.2e-43 gcvR T Belongs to the UPF0237 family
MGEDCBFO_00267 1.1e-242 EGP Sugar (and other) transporter
MGEDCBFO_00268 0.0 tetP J Elongation factor G, domain IV
MGEDCBFO_00269 7.4e-27
MGEDCBFO_00270 3.8e-114 parA D AAA domain
MGEDCBFO_00271 7.5e-91 S Transcription factor WhiB
MGEDCBFO_00272 1.6e-41
MGEDCBFO_00273 2.7e-173 S Helix-turn-helix domain
MGEDCBFO_00274 9.2e-18
MGEDCBFO_00275 8.6e-118
MGEDCBFO_00276 1.3e-119
MGEDCBFO_00277 6.2e-58
MGEDCBFO_00278 3.1e-174 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MGEDCBFO_00279 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
MGEDCBFO_00280 1.6e-41 P ABC-type metal ion transport system permease component
MGEDCBFO_00281 6.3e-10 P ABC-type metal ion transport system permease component
MGEDCBFO_00282 5e-223 S Peptidase dimerisation domain
MGEDCBFO_00283 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MGEDCBFO_00284 6.4e-40
MGEDCBFO_00285 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MGEDCBFO_00286 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MGEDCBFO_00287 4.4e-114 S Protein of unknown function (DUF3000)
MGEDCBFO_00288 2.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
MGEDCBFO_00289 8.1e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MGEDCBFO_00290 6.1e-255 clcA_2 P Voltage gated chloride channel
MGEDCBFO_00291 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MGEDCBFO_00292 9.4e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MGEDCBFO_00293 9.1e-245 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MGEDCBFO_00296 1.7e-234 patB 4.4.1.8 E Aminotransferase, class I II
MGEDCBFO_00297 1.2e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MGEDCBFO_00298 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
MGEDCBFO_00299 4.4e-118 safC S O-methyltransferase
MGEDCBFO_00300 4.3e-183 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
MGEDCBFO_00301 2.8e-69 yraN L Belongs to the UPF0102 family
MGEDCBFO_00302 1.2e-293 comM O Magnesium chelatase, subunit ChlI C-terminal
MGEDCBFO_00303 5.7e-283 dprA 5.99.1.2 LU DNA recombination-mediator protein A
MGEDCBFO_00304 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
MGEDCBFO_00305 7.3e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MGEDCBFO_00306 1.6e-157 S Putative ABC-transporter type IV
MGEDCBFO_00307 1e-251 metY 2.5.1.49 E Aminotransferase class-V
MGEDCBFO_00308 3.5e-161 V ABC transporter, ATP-binding protein
MGEDCBFO_00309 0.0 MV MacB-like periplasmic core domain
MGEDCBFO_00310 0.0 phoN I PAP2 superfamily
MGEDCBFO_00311 6.1e-132 K helix_turn_helix, Lux Regulon
MGEDCBFO_00312 0.0 tcsS2 T Histidine kinase
MGEDCBFO_00313 5.5e-264 pip 3.4.11.5 S alpha/beta hydrolase fold
MGEDCBFO_00314 5.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MGEDCBFO_00315 3.5e-166 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
MGEDCBFO_00316 1.6e-146 P NLPA lipoprotein
MGEDCBFO_00317 7.7e-188 acoA 1.2.4.1 C Dehydrogenase E1 component
MGEDCBFO_00318 3.2e-184 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
MGEDCBFO_00319 1.6e-205 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MGEDCBFO_00320 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
MGEDCBFO_00321 1.1e-228 mtnE 2.6.1.83 E Aminotransferase class I and II
MGEDCBFO_00322 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MGEDCBFO_00323 3.1e-245 XK27_00240 K Fic/DOC family
MGEDCBFO_00324 1.4e-117 E Psort location Cytoplasmic, score 8.87
MGEDCBFO_00325 5.6e-59 yccF S Inner membrane component domain
MGEDCBFO_00326 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
MGEDCBFO_00327 9.7e-63 S Cupin 2, conserved barrel domain protein
MGEDCBFO_00328 1.3e-256 KLT Protein tyrosine kinase
MGEDCBFO_00329 4.5e-79 K Psort location Cytoplasmic, score
MGEDCBFO_00331 2.9e-12
MGEDCBFO_00332 2.7e-22
MGEDCBFO_00333 2.5e-199 S Short C-terminal domain
MGEDCBFO_00334 8.2e-91 S Helix-turn-helix
MGEDCBFO_00335 2.8e-66 S Zincin-like metallopeptidase
MGEDCBFO_00336 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MGEDCBFO_00337 2.5e-24
MGEDCBFO_00338 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MGEDCBFO_00339 3e-124 ypfH S Phospholipase/Carboxylesterase
MGEDCBFO_00340 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MGEDCBFO_00341 4.8e-129 S Metallo-beta-lactamase domain protein
MGEDCBFO_00342 5.6e-108
MGEDCBFO_00343 3.5e-257 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
MGEDCBFO_00344 1.2e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MGEDCBFO_00345 2.6e-163 glcU G Sugar transport protein
MGEDCBFO_00346 1.3e-122 K helix_turn_helix, arabinose operon control protein
MGEDCBFO_00348 3.9e-36 rpmE J Binds the 23S rRNA
MGEDCBFO_00349 4.5e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MGEDCBFO_00350 1.5e-186 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MGEDCBFO_00351 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
MGEDCBFO_00352 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
MGEDCBFO_00353 8e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
MGEDCBFO_00354 3.5e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MGEDCBFO_00355 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MGEDCBFO_00356 3.1e-39 KT Transcriptional regulatory protein, C terminal
MGEDCBFO_00357 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MGEDCBFO_00358 1.1e-161 supH S Sucrose-6F-phosphate phosphohydrolase
MGEDCBFO_00359 2.5e-269 recD2 3.6.4.12 L PIF1-like helicase
MGEDCBFO_00361 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MGEDCBFO_00362 3.2e-170
MGEDCBFO_00363 2.2e-104 L Single-strand binding protein family
MGEDCBFO_00364 0.0 pepO 3.4.24.71 O Peptidase family M13
MGEDCBFO_00365 3.1e-127 S Short repeat of unknown function (DUF308)
MGEDCBFO_00366 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
MGEDCBFO_00367 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
MGEDCBFO_00368 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
MGEDCBFO_00369 1.9e-197 yghZ C Aldo/keto reductase family
MGEDCBFO_00370 0.0 ctpE P E1-E2 ATPase
MGEDCBFO_00371 0.0 macB_2 V ATPases associated with a variety of cellular activities
MGEDCBFO_00372 3.4e-217 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MGEDCBFO_00373 2.8e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
MGEDCBFO_00374 2.2e-232 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MGEDCBFO_00375 1.8e-240 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
MGEDCBFO_00376 7e-127 XK27_08050 O prohibitin homologues
MGEDCBFO_00377 2.7e-274 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
MGEDCBFO_00378 5e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MGEDCBFO_00379 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MGEDCBFO_00380 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MGEDCBFO_00381 1.7e-239 hsdM 2.1.1.72 V HsdM N-terminal domain
MGEDCBFO_00382 1e-56 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
MGEDCBFO_00383 2.6e-16 K Helix-turn-helix domain
MGEDCBFO_00384 2.3e-19 S Protein of unknown function (DUF2442)
MGEDCBFO_00385 8.3e-29 L Helix-turn-helix domain
MGEDCBFO_00386 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
MGEDCBFO_00387 8.5e-20 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MGEDCBFO_00388 6.5e-190 K Periplasmic binding protein domain
MGEDCBFO_00389 2e-126 G ABC transporter permease
MGEDCBFO_00390 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MGEDCBFO_00391 3.8e-66 G carbohydrate transport
MGEDCBFO_00392 1.1e-275 G Bacterial extracellular solute-binding protein
MGEDCBFO_00393 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MGEDCBFO_00394 1.8e-309 E ABC transporter, substrate-binding protein, family 5
MGEDCBFO_00395 1.4e-170 P Binding-protein-dependent transport system inner membrane component
MGEDCBFO_00396 4.9e-163 EP Binding-protein-dependent transport system inner membrane component
MGEDCBFO_00397 4e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
MGEDCBFO_00398 9.8e-155 sapF E ATPases associated with a variety of cellular activities
MGEDCBFO_00399 7e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MGEDCBFO_00400 1.8e-240 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
MGEDCBFO_00401 2.5e-139 rgpC U Transport permease protein
MGEDCBFO_00402 0.0 wbbM M Glycosyl transferase family 8
MGEDCBFO_00403 8.4e-216 1.1.1.22 M UDP binding domain
MGEDCBFO_00404 4.4e-15 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MGEDCBFO_00405 7.9e-153 K Transposase IS116 IS110 IS902
MGEDCBFO_00406 7.3e-119 tnp7109-21 L Integrase core domain
MGEDCBFO_00407 2.6e-43 L Transposase
MGEDCBFO_00408 3.3e-09
MGEDCBFO_00410 9.5e-45 L Transposase DDE domain
MGEDCBFO_00411 3e-155 bglA 3.2.1.21 G Glycosyl hydrolase family 1
MGEDCBFO_00412 2e-203 L Transposase, Mutator family
MGEDCBFO_00413 6.9e-228 glf 5.4.99.9 M UDP-galactopyranose mutase
MGEDCBFO_00414 6.1e-45 3.6.1.13 L NUDIX domain
MGEDCBFO_00415 1.4e-102
MGEDCBFO_00416 5.6e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MGEDCBFO_00417 1e-216 G Transmembrane secretion effector
MGEDCBFO_00418 2.7e-118 K Bacterial regulatory proteins, tetR family
MGEDCBFO_00419 4.5e-12
MGEDCBFO_00420 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
MGEDCBFO_00421 1.1e-42 tnp7109-21 L Integrase core domain
MGEDCBFO_00422 2.1e-32 L IstB-like ATP binding protein
MGEDCBFO_00423 3.6e-84 V ATPases associated with a variety of cellular activities
MGEDCBFO_00424 2e-73 I Sterol carrier protein
MGEDCBFO_00425 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MGEDCBFO_00426 3.4e-35
MGEDCBFO_00427 1.4e-144 gluP 3.4.21.105 S Rhomboid family
MGEDCBFO_00428 3.9e-124 L HTH-like domain
MGEDCBFO_00429 1.6e-257 L ribosomal rna small subunit methyltransferase
MGEDCBFO_00430 2.6e-71 crgA D Involved in cell division
MGEDCBFO_00431 3.5e-143 S Bacterial protein of unknown function (DUF881)
MGEDCBFO_00432 5.4e-231 srtA 3.4.22.70 M Sortase family
MGEDCBFO_00433 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
MGEDCBFO_00434 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
MGEDCBFO_00435 2e-183 T Protein tyrosine kinase
MGEDCBFO_00436 9.8e-264 pbpA M penicillin-binding protein
MGEDCBFO_00437 1.1e-265 rodA D Belongs to the SEDS family
MGEDCBFO_00438 6.9e-258 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
MGEDCBFO_00439 5.2e-93 fhaB T Inner membrane component of T3SS, cytoplasmic domain
MGEDCBFO_00440 1e-130 fhaA T Protein of unknown function (DUF2662)
MGEDCBFO_00441 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
MGEDCBFO_00442 0.0 pip S YhgE Pip domain protein
MGEDCBFO_00443 0.0 pip S YhgE Pip domain protein
MGEDCBFO_00444 4.6e-207 pldB 3.1.1.5 I Serine aminopeptidase, S33
MGEDCBFO_00445 4.4e-159 yicL EG EamA-like transporter family
MGEDCBFO_00446 2e-103
MGEDCBFO_00448 5.4e-197 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MGEDCBFO_00450 0.0 KL Domain of unknown function (DUF3427)
MGEDCBFO_00451 2.5e-89 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MGEDCBFO_00452 3.7e-40 D DivIVA domain protein
MGEDCBFO_00453 6.5e-17 ybjQ S Putative heavy-metal-binding
MGEDCBFO_00454 0.0 S AIPR protein
MGEDCBFO_00455 1.7e-150 S Putative PD-(D/E)XK family member, (DUF4420)
MGEDCBFO_00456 0.0 L Z1 domain
MGEDCBFO_00457 2.3e-252 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MGEDCBFO_00458 6.2e-245 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
MGEDCBFO_00459 2.4e-23 ykoE S ABC-type cobalt transport system, permease component
MGEDCBFO_00460 4.3e-149 S Virulence factor BrkB
MGEDCBFO_00461 7.6e-100 bcp 1.11.1.15 O Redoxin
MGEDCBFO_00462 1.2e-39 E ABC transporter
MGEDCBFO_00463 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MGEDCBFO_00464 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MGEDCBFO_00465 0.0 V FtsX-like permease family
MGEDCBFO_00466 2.6e-129 V ABC transporter
MGEDCBFO_00467 2.4e-101 K Transcriptional regulator C-terminal region
MGEDCBFO_00468 1.5e-275 aroP E aromatic amino acid transport protein AroP K03293
MGEDCBFO_00469 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MGEDCBFO_00470 9.7e-183 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
MGEDCBFO_00471 4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MGEDCBFO_00472 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MGEDCBFO_00473 2.9e-254 yhjE EGP Sugar (and other) transporter
MGEDCBFO_00474 1.6e-294 scrT G Transporter major facilitator family protein
MGEDCBFO_00475 4.8e-78 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
MGEDCBFO_00476 8.4e-193 K helix_turn _helix lactose operon repressor
MGEDCBFO_00477 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MGEDCBFO_00478 3.7e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MGEDCBFO_00479 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MGEDCBFO_00480 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MGEDCBFO_00481 1.6e-246 3.5.1.104 G Polysaccharide deacetylase
MGEDCBFO_00482 4.9e-57 K Cro/C1-type HTH DNA-binding domain
MGEDCBFO_00483 2e-12 E IrrE N-terminal-like domain
MGEDCBFO_00484 3.9e-50 E IrrE N-terminal-like domain
MGEDCBFO_00485 9.9e-64
MGEDCBFO_00486 1.9e-61
MGEDCBFO_00488 2.3e-127 S Domain of unknown function (DUF4417)
MGEDCBFO_00489 1.9e-42 S Bacterial mobilisation protein (MobC)
MGEDCBFO_00490 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MGEDCBFO_00492 9.9e-169 htpX O Belongs to the peptidase M48B family
MGEDCBFO_00493 1.1e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
MGEDCBFO_00494 0.0 cadA P E1-E2 ATPase
MGEDCBFO_00495 1.4e-241 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
MGEDCBFO_00496 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MGEDCBFO_00498 4.1e-86 yjcF Q Acetyltransferase (GNAT) domain
MGEDCBFO_00499 4.5e-157 I Serine aminopeptidase, S33
MGEDCBFO_00500 1.8e-28 ybjQ S Putative heavy-metal-binding
MGEDCBFO_00501 0.0 XK27_00515 D Cell surface antigen C-terminus
MGEDCBFO_00502 5.2e-26
MGEDCBFO_00503 5.3e-145
MGEDCBFO_00504 1.4e-62 S PrgI family protein
MGEDCBFO_00505 0.0 trsE U type IV secretory pathway VirB4
MGEDCBFO_00506 5.4e-205 isp2 3.2.1.96 M CHAP domain
MGEDCBFO_00507 3.6e-14 U Type IV secretory system Conjugative DNA transfer
MGEDCBFO_00508 2.9e-130
MGEDCBFO_00509 5.9e-101 K DNA binding
MGEDCBFO_00510 2.4e-101 dam2 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
MGEDCBFO_00511 3e-09
MGEDCBFO_00513 0.0 U Type IV secretory system Conjugative DNA transfer
MGEDCBFO_00514 9.3e-31
MGEDCBFO_00515 3.2e-39
MGEDCBFO_00516 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MGEDCBFO_00518 1.7e-284
MGEDCBFO_00519 1.1e-163 S Protein of unknown function (DUF3801)
MGEDCBFO_00520 5.4e-279 ltrBE1 U Relaxase/Mobilisation nuclease domain
MGEDCBFO_00521 6.9e-52 S Bacterial mobilisation protein (MobC)
MGEDCBFO_00522 3.6e-41 S Protein of unknown function (DUF2442)
MGEDCBFO_00523 3e-55
MGEDCBFO_00524 1.5e-86
MGEDCBFO_00525 0.0 topB 5.99.1.2 L DNA topoisomerase
MGEDCBFO_00526 2.9e-82
MGEDCBFO_00527 9.4e-60
MGEDCBFO_00528 5.8e-48
MGEDCBFO_00529 5.9e-228 S HipA-like C-terminal domain
MGEDCBFO_00531 1.6e-17 S Maff2 family
MGEDCBFO_00532 0.0 U Type IV secretory system Conjugative DNA transfer
MGEDCBFO_00533 1.4e-57 S Protein of unknown function (DUF3801)
MGEDCBFO_00534 9.5e-35 S Psort location Cytoplasmic, score
MGEDCBFO_00535 1.8e-164 L Psort location Cytoplasmic, score
MGEDCBFO_00536 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
MGEDCBFO_00537 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
MGEDCBFO_00538 3.1e-139 glpR K DeoR C terminal sensor domain
MGEDCBFO_00539 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MGEDCBFO_00540 3.1e-217 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
MGEDCBFO_00541 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MGEDCBFO_00542 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
MGEDCBFO_00543 4.3e-214 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
MGEDCBFO_00544 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MGEDCBFO_00545 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
MGEDCBFO_00546 1.1e-240 S Uncharacterized conserved protein (DUF2183)
MGEDCBFO_00547 4.9e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MGEDCBFO_00548 0.0 enhA_2 S L,D-transpeptidase catalytic domain
MGEDCBFO_00549 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MGEDCBFO_00550 3.4e-160 mhpC I Alpha/beta hydrolase family
MGEDCBFO_00551 4.8e-119 F Domain of unknown function (DUF4916)
MGEDCBFO_00552 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
MGEDCBFO_00553 1.3e-179 S G5
MGEDCBFO_00554 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
MGEDCBFO_00555 0.0 lmrA2 V ABC transporter transmembrane region
MGEDCBFO_00556 0.0 lmrA1 V ABC transporter, ATP-binding protein
MGEDCBFO_00557 6.5e-93 ydgJ K helix_turn_helix multiple antibiotic resistance protein
MGEDCBFO_00558 3.3e-191 1.1.1.65 C Aldo/keto reductase family
MGEDCBFO_00560 4e-100 M Belongs to the glycosyl hydrolase 30 family
MGEDCBFO_00561 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
MGEDCBFO_00563 1.4e-90 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
MGEDCBFO_00564 5e-116 K WHG domain
MGEDCBFO_00565 6.8e-36 L Psort location Cytoplasmic, score 8.87
MGEDCBFO_00566 1e-133 L Integrase core domain
MGEDCBFO_00567 3.5e-41 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
MGEDCBFO_00568 1.7e-266 EGP Major Facilitator Superfamily
MGEDCBFO_00569 4.9e-117
MGEDCBFO_00570 2.9e-243 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MGEDCBFO_00571 5.5e-55 L HNH endonuclease
MGEDCBFO_00572 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MGEDCBFO_00573 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MGEDCBFO_00574 1e-178 L Phage integrase family
MGEDCBFO_00575 4.9e-82 3.1.21.3 V type I restriction modification DNA specificity domain
MGEDCBFO_00576 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MGEDCBFO_00577 7.1e-84 argR K Regulates arginine biosynthesis genes
MGEDCBFO_00578 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MGEDCBFO_00579 2.8e-246 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
MGEDCBFO_00580 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MGEDCBFO_00581 1.8e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MGEDCBFO_00582 7.7e-205 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MGEDCBFO_00583 1.4e-89
MGEDCBFO_00584 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
MGEDCBFO_00585 7e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MGEDCBFO_00586 7.8e-160 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MGEDCBFO_00587 1.2e-135 ybbL V ATPases associated with a variety of cellular activities
MGEDCBFO_00588 4.2e-136 ybbM V Uncharacterised protein family (UPF0014)
MGEDCBFO_00589 6e-42 IQ oxidoreductase activity
MGEDCBFO_00591 8e-94 K AraC-like ligand binding domain
MGEDCBFO_00592 2.4e-237 rutG F Permease family
MGEDCBFO_00593 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
MGEDCBFO_00594 4.2e-63 S Phospholipase/Carboxylesterase
MGEDCBFO_00595 3.2e-187 MA20_14895 S Conserved hypothetical protein 698
MGEDCBFO_00596 7.8e-146 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
MGEDCBFO_00597 2.1e-117 3.1.3.27 E haloacid dehalogenase-like hydrolase
MGEDCBFO_00598 2.2e-290 2.4.1.166 GT2 M Glycosyltransferase like family 2
MGEDCBFO_00600 4.4e-111
MGEDCBFO_00601 2e-155 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
MGEDCBFO_00602 3.1e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
MGEDCBFO_00603 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
MGEDCBFO_00604 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
MGEDCBFO_00605 1.6e-163 EG EamA-like transporter family
MGEDCBFO_00607 4.5e-125 V FtsX-like permease family
MGEDCBFO_00608 9.1e-148 S Sulfite exporter TauE/SafE
MGEDCBFO_00610 1.9e-26 L Transposase
MGEDCBFO_00611 3.4e-216 MA20_36090 S Psort location Cytoplasmic, score 8.87
MGEDCBFO_00612 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
MGEDCBFO_00613 3.3e-50 EGP Major facilitator superfamily
MGEDCBFO_00614 1.2e-11 EGP Major facilitator superfamily
MGEDCBFO_00615 5.2e-10 K Winged helix DNA-binding domain
MGEDCBFO_00616 3.7e-179 glkA 2.7.1.2 G ROK family
MGEDCBFO_00617 1.1e-300 S ATPases associated with a variety of cellular activities
MGEDCBFO_00618 1.2e-55 EGP Major facilitator Superfamily
MGEDCBFO_00619 1.7e-159 I alpha/beta hydrolase fold
MGEDCBFO_00620 1.9e-115 S Pyridoxamine 5'-phosphate oxidase
MGEDCBFO_00622 1.3e-76 S DUF218 domain
MGEDCBFO_00624 8.4e-52 S Protein of unknown function (DUF979)
MGEDCBFO_00625 4.4e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MGEDCBFO_00627 2e-126
MGEDCBFO_00628 4.7e-48 M domain, Protein
MGEDCBFO_00629 4e-19 M domain, Protein
MGEDCBFO_00630 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
MGEDCBFO_00631 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
MGEDCBFO_00632 2.1e-171 tesB I Thioesterase-like superfamily
MGEDCBFO_00633 2.2e-75 S Protein of unknown function (DUF3180)
MGEDCBFO_00634 2.1e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MGEDCBFO_00635 1.9e-161 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MGEDCBFO_00636 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
MGEDCBFO_00637 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MGEDCBFO_00638 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MGEDCBFO_00639 3.5e-213 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MGEDCBFO_00640 1e-260 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
MGEDCBFO_00641 3.1e-136
MGEDCBFO_00642 6.5e-152
MGEDCBFO_00643 4.9e-168 natA V ATPases associated with a variety of cellular activities
MGEDCBFO_00644 1.3e-232 epsG M Glycosyl transferase family 21
MGEDCBFO_00645 4.3e-273 S AI-2E family transporter
MGEDCBFO_00646 1.9e-177 3.4.14.13 M Glycosyltransferase like family 2
MGEDCBFO_00647 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
MGEDCBFO_00650 2.6e-68 S Domain of unknown function (DUF4190)
MGEDCBFO_00651 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MGEDCBFO_00652 7e-155 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MGEDCBFO_00654 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
MGEDCBFO_00655 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MGEDCBFO_00656 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
MGEDCBFO_00657 1e-183 lacR K Transcriptional regulator, LacI family
MGEDCBFO_00658 5.2e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MGEDCBFO_00659 3.9e-119 K Transcriptional regulatory protein, C terminal
MGEDCBFO_00660 1.4e-100
MGEDCBFO_00661 1.5e-178 V N-Acetylmuramoyl-L-alanine amidase
MGEDCBFO_00662 7.4e-109 ytrE V ABC transporter
MGEDCBFO_00663 6.6e-172
MGEDCBFO_00664 1.5e-12 S Psort location CytoplasmicMembrane, score 9.99
MGEDCBFO_00665 2.3e-219 vex3 V ABC transporter permease
MGEDCBFO_00666 1.5e-209 vex1 V Efflux ABC transporter, permease protein
MGEDCBFO_00667 9.9e-112 vex2 V ABC transporter, ATP-binding protein
MGEDCBFO_00668 2.2e-38 azlD E Branched-chain amino acid transport protein (AzlD)
MGEDCBFO_00669 2.2e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
MGEDCBFO_00670 2.1e-96 ptpA 3.1.3.48 T low molecular weight
MGEDCBFO_00671 5.1e-127 folA 1.5.1.3 H dihydrofolate reductase
MGEDCBFO_00672 1.6e-173 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MGEDCBFO_00673 1e-72 attW O OsmC-like protein
MGEDCBFO_00674 1.6e-191 T Universal stress protein family
MGEDCBFO_00675 2.4e-107 M NlpC/P60 family
MGEDCBFO_00676 1.4e-179 usp 3.5.1.28 CBM50 S CHAP domain
MGEDCBFO_00677 4.2e-214 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MGEDCBFO_00678 2.6e-39
MGEDCBFO_00679 1.6e-217 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MGEDCBFO_00680 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
MGEDCBFO_00681 2.3e-09 EGP Major facilitator Superfamily
MGEDCBFO_00682 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MGEDCBFO_00683 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MGEDCBFO_00684 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MGEDCBFO_00686 4.3e-217 araJ EGP Major facilitator Superfamily
MGEDCBFO_00687 0.0 S Domain of unknown function (DUF4037)
MGEDCBFO_00688 1.5e-112 S Protein of unknown function (DUF4125)
MGEDCBFO_00689 7.3e-135
MGEDCBFO_00690 1.4e-288 pspC KT PspC domain
MGEDCBFO_00691 2.7e-266 tcsS3 KT PspC domain
MGEDCBFO_00692 9.2e-126 degU K helix_turn_helix, Lux Regulon
MGEDCBFO_00693 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MGEDCBFO_00695 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MGEDCBFO_00696 4.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
MGEDCBFO_00697 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MGEDCBFO_00698 1.7e-93
MGEDCBFO_00700 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
MGEDCBFO_00702 3e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MGEDCBFO_00703 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
MGEDCBFO_00704 6.7e-212 I Diacylglycerol kinase catalytic domain
MGEDCBFO_00705 1.3e-151 arbG K CAT RNA binding domain
MGEDCBFO_00706 0.0 crr G pts system, glucose-specific IIABC component
MGEDCBFO_00707 6.8e-43 M Spy0128-like isopeptide containing domain
MGEDCBFO_00708 1.6e-43 M Spy0128-like isopeptide containing domain
MGEDCBFO_00709 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MGEDCBFO_00710 7.5e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MGEDCBFO_00711 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
MGEDCBFO_00712 1.2e-202 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MGEDCBFO_00713 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MGEDCBFO_00715 8e-106
MGEDCBFO_00716 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MGEDCBFO_00717 8.5e-232 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
MGEDCBFO_00718 2.1e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MGEDCBFO_00719 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MGEDCBFO_00720 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MGEDCBFO_00721 2.8e-188 nusA K Participates in both transcription termination and antitermination
MGEDCBFO_00722 8.7e-160
MGEDCBFO_00723 6e-72 L Transposase and inactivated derivatives
MGEDCBFO_00724 1.7e-33
MGEDCBFO_00726 1.3e-153 E Transglutaminase/protease-like homologues
MGEDCBFO_00727 0.0 gcs2 S A circularly permuted ATPgrasp
MGEDCBFO_00728 8.3e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MGEDCBFO_00729 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
MGEDCBFO_00730 2.8e-64 rplQ J Ribosomal protein L17
MGEDCBFO_00731 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MGEDCBFO_00732 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MGEDCBFO_00733 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MGEDCBFO_00734 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MGEDCBFO_00735 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MGEDCBFO_00736 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MGEDCBFO_00737 8.9e-248 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MGEDCBFO_00738 2.7e-63 rplO J binds to the 23S rRNA
MGEDCBFO_00739 1e-24 rpmD J Ribosomal protein L30p/L7e
MGEDCBFO_00740 1.9e-98 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MGEDCBFO_00741 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MGEDCBFO_00742 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MGEDCBFO_00743 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MGEDCBFO_00744 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MGEDCBFO_00745 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MGEDCBFO_00746 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MGEDCBFO_00747 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MGEDCBFO_00748 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MGEDCBFO_00749 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
MGEDCBFO_00750 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MGEDCBFO_00751 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MGEDCBFO_00752 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MGEDCBFO_00753 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MGEDCBFO_00754 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MGEDCBFO_00755 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MGEDCBFO_00756 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
MGEDCBFO_00757 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MGEDCBFO_00758 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
MGEDCBFO_00759 3e-14 ywiC S YwiC-like protein
MGEDCBFO_00760 1.9e-111 ywiC S YwiC-like protein
MGEDCBFO_00761 9.7e-166 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MGEDCBFO_00762 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MGEDCBFO_00763 3.1e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MGEDCBFO_00764 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MGEDCBFO_00765 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
MGEDCBFO_00766 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MGEDCBFO_00767 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MGEDCBFO_00768 1.8e-120
MGEDCBFO_00769 1.1e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
MGEDCBFO_00770 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
MGEDCBFO_00772 1.6e-238 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MGEDCBFO_00773 7.9e-224 dapC E Aminotransferase class I and II
MGEDCBFO_00774 9e-61 fdxA C 4Fe-4S binding domain
MGEDCBFO_00775 6.9e-215 murB 1.3.1.98 M Cell wall formation
MGEDCBFO_00776 1.9e-25 rpmG J Ribosomal protein L33
MGEDCBFO_00780 2e-50 moxR S ATPase family associated with various cellular activities (AAA)
MGEDCBFO_00781 2.1e-132 bla1 3.5.2.6 V Beta-lactamase enzyme family
MGEDCBFO_00782 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MGEDCBFO_00783 2.4e-147
MGEDCBFO_00784 2.3e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
MGEDCBFO_00785 2e-120 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
MGEDCBFO_00786 3.2e-38 fmdB S Putative regulatory protein
MGEDCBFO_00787 8.5e-91 flgA NO SAF
MGEDCBFO_00788 9.6e-42
MGEDCBFO_00789 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
MGEDCBFO_00790 3.6e-238 T Forkhead associated domain
MGEDCBFO_00792 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MGEDCBFO_00793 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MGEDCBFO_00794 1.8e-184 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
MGEDCBFO_00795 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
MGEDCBFO_00796 8.8e-222 pbuO S Permease family
MGEDCBFO_00797 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MGEDCBFO_00798 9.2e-170 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MGEDCBFO_00799 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MGEDCBFO_00800 6.2e-180 pstA P Phosphate transport system permease
MGEDCBFO_00801 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
MGEDCBFO_00802 3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
MGEDCBFO_00803 1.3e-128 KT Transcriptional regulatory protein, C terminal
MGEDCBFO_00804 7.2e-245 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MGEDCBFO_00805 4.3e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MGEDCBFO_00806 1.1e-239 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MGEDCBFO_00807 9.7e-109 K helix_turn_helix, Arsenical Resistance Operon Repressor
MGEDCBFO_00808 3e-246 EGP Major facilitator Superfamily
MGEDCBFO_00809 1.5e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MGEDCBFO_00810 1.7e-169 L Excalibur calcium-binding domain
MGEDCBFO_00811 1.2e-268 pepC 3.4.22.40 E Peptidase C1-like family
MGEDCBFO_00812 3.1e-52 D nuclear chromosome segregation
MGEDCBFO_00813 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MGEDCBFO_00814 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MGEDCBFO_00815 1.3e-187 yfiH Q Multi-copper polyphenol oxidoreductase laccase
MGEDCBFO_00816 0.0 yegQ O Peptidase family U32 C-terminal domain
MGEDCBFO_00817 3.6e-94 L Transposase and inactivated derivatives IS30 family
MGEDCBFO_00818 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
MGEDCBFO_00819 2.2e-41 nrdH O Glutaredoxin
MGEDCBFO_00820 1.4e-96 nrdI F Probably involved in ribonucleotide reductase function
MGEDCBFO_00821 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MGEDCBFO_00822 1.8e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MGEDCBFO_00823 1.2e-74 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MGEDCBFO_00824 0.0 S Predicted membrane protein (DUF2207)
MGEDCBFO_00825 8.6e-91 lemA S LemA family
MGEDCBFO_00826 1e-158 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
MGEDCBFO_00827 3e-228 2.7.7.7 L Transposase and inactivated derivatives
MGEDCBFO_00828 8.7e-28 L DNA integration
MGEDCBFO_00829 2e-24
MGEDCBFO_00830 1.2e-87 L Transposase
MGEDCBFO_00831 4.5e-85
MGEDCBFO_00832 2.6e-112 bepIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
MGEDCBFO_00833 4e-181 L HTH-like domain
MGEDCBFO_00834 3.3e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MGEDCBFO_00835 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MGEDCBFO_00836 3.4e-189 pit P Phosphate transporter family
MGEDCBFO_00837 1.1e-115 MA20_27875 P Protein of unknown function DUF47
MGEDCBFO_00838 3.1e-119 K helix_turn_helix, Lux Regulon
MGEDCBFO_00839 9.2e-234 T Histidine kinase
MGEDCBFO_00840 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MGEDCBFO_00841 2.9e-179 V ATPases associated with a variety of cellular activities
MGEDCBFO_00842 1.7e-224 V ABC-2 family transporter protein
MGEDCBFO_00843 8.5e-249 V ABC-2 family transporter protein
MGEDCBFO_00844 1.7e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MGEDCBFO_00845 4.3e-205 L Transposase and inactivated derivatives IS30 family
MGEDCBFO_00847 3e-91
MGEDCBFO_00848 1.2e-64 D MobA/MobL family
MGEDCBFO_00849 8.6e-48 L Transposase
MGEDCBFO_00850 1.7e-181 tnp7109-21 L Integrase core domain
MGEDCBFO_00851 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
MGEDCBFO_00852 9e-40
MGEDCBFO_00853 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
MGEDCBFO_00855 8.3e-108 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MGEDCBFO_00856 8.1e-47 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MGEDCBFO_00858 4.1e-240 pbuX F Permease family
MGEDCBFO_00859 1.9e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MGEDCBFO_00860 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
MGEDCBFO_00861 0.0 pcrA 3.6.4.12 L DNA helicase
MGEDCBFO_00862 8.2e-64 S Domain of unknown function (DUF4418)
MGEDCBFO_00863 7.2e-212 V FtsX-like permease family
MGEDCBFO_00864 1.9e-128 lolD V ABC transporter
MGEDCBFO_00865 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MGEDCBFO_00866 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
MGEDCBFO_00867 6.5e-136 pgm3 G Phosphoglycerate mutase family
MGEDCBFO_00868 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
MGEDCBFO_00869 1.1e-36
MGEDCBFO_00870 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MGEDCBFO_00871 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MGEDCBFO_00872 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MGEDCBFO_00873 1.3e-47 3.4.23.43 S Type IV leader peptidase family
MGEDCBFO_00874 1.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MGEDCBFO_00875 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MGEDCBFO_00876 5.9e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MGEDCBFO_00877 1.9e-75
MGEDCBFO_00878 1.7e-120 K helix_turn_helix, Lux Regulon
MGEDCBFO_00879 2.6e-07 3.4.22.70 M Sortase family
MGEDCBFO_00880 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MGEDCBFO_00881 4.8e-290 sufB O FeS assembly protein SufB
MGEDCBFO_00882 5.7e-233 sufD O FeS assembly protein SufD
MGEDCBFO_00883 1.4e-144 sufC O FeS assembly ATPase SufC
MGEDCBFO_00884 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MGEDCBFO_00885 1.5e-100 iscU C SUF system FeS assembly protein, NifU family
MGEDCBFO_00886 4.7e-108 yitW S Iron-sulfur cluster assembly protein
MGEDCBFO_00887 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MGEDCBFO_00888 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
MGEDCBFO_00890 2.1e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MGEDCBFO_00891 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
MGEDCBFO_00892 2e-197 phoH T PhoH-like protein
MGEDCBFO_00893 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MGEDCBFO_00894 2.4e-251 corC S CBS domain
MGEDCBFO_00895 5.1e-187 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MGEDCBFO_00896 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MGEDCBFO_00897 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
MGEDCBFO_00898 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
MGEDCBFO_00899 6.7e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MGEDCBFO_00900 3.1e-189 S alpha beta
MGEDCBFO_00901 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MGEDCBFO_00902 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
MGEDCBFO_00903 4e-46 S phosphoesterase or phosphohydrolase
MGEDCBFO_00904 2.7e-99 3.1.4.37 T RNA ligase
MGEDCBFO_00905 1.2e-135 S UPF0126 domain
MGEDCBFO_00906 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
MGEDCBFO_00907 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MGEDCBFO_00908 3e-246 hemN H Involved in the biosynthesis of porphyrin-containing compound
MGEDCBFO_00909 4e-13 S Membrane
MGEDCBFO_00910 4.5e-291 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
MGEDCBFO_00911 0.0 tetP J Elongation factor G, domain IV
MGEDCBFO_00912 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
MGEDCBFO_00913 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MGEDCBFO_00914 3.6e-82
MGEDCBFO_00915 4.3e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
MGEDCBFO_00916 8.9e-164 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
MGEDCBFO_00917 6.5e-157 ybeM S Carbon-nitrogen hydrolase
MGEDCBFO_00918 1e-110 S Sel1-like repeats.
MGEDCBFO_00919 7.7e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MGEDCBFO_00920 2.9e-107 S Putative inner membrane protein (DUF1819)
MGEDCBFO_00921 1.3e-125 S Domain of unknown function (DUF1788)
MGEDCBFO_00922 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
MGEDCBFO_00923 0.0 LV DNA restriction-modification system
MGEDCBFO_00924 8.4e-75 S Domain of unknown function (DUF4263)
MGEDCBFO_00925 9.9e-259 lexA 3.6.4.12 K Putative DNA-binding domain
MGEDCBFO_00926 0.0 thiN 2.7.6.2 H PglZ domain
MGEDCBFO_00927 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
MGEDCBFO_00928 2.1e-144
MGEDCBFO_00930 9.7e-191 mcrB L Restriction endonuclease
MGEDCBFO_00931 2.5e-29
MGEDCBFO_00932 3.2e-92 rarD 3.4.17.13 E Rard protein
MGEDCBFO_00933 1.4e-23 rarD S EamA-like transporter family
MGEDCBFO_00934 8.8e-178 I alpha/beta hydrolase fold
MGEDCBFO_00935 2.2e-207 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MGEDCBFO_00936 1.2e-100 sixA T Phosphoglycerate mutase family
MGEDCBFO_00937 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MGEDCBFO_00938 2.8e-162 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
MGEDCBFO_00940 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MGEDCBFO_00941 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MGEDCBFO_00942 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MGEDCBFO_00943 9.4e-280 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MGEDCBFO_00944 3.4e-180 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
MGEDCBFO_00945 1.9e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MGEDCBFO_00946 5.2e-181 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MGEDCBFO_00947 6.5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MGEDCBFO_00948 1e-16 K MerR family regulatory protein
MGEDCBFO_00949 4.7e-196 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MGEDCBFO_00950 2.2e-138
MGEDCBFO_00952 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MGEDCBFO_00953 4.8e-241 vbsD V MatE
MGEDCBFO_00954 3.6e-131 S Enoyl-(Acyl carrier protein) reductase
MGEDCBFO_00955 3.9e-133 magIII L endonuclease III
MGEDCBFO_00956 1.4e-92 laaE K Transcriptional regulator PadR-like family
MGEDCBFO_00957 1.8e-176 S Membrane transport protein
MGEDCBFO_00958 1.1e-67 4.1.1.44 S Cupin domain
MGEDCBFO_00959 7e-225 hipA 2.7.11.1 S HipA N-terminal domain
MGEDCBFO_00960 3.7e-41 K Helix-turn-helix
MGEDCBFO_00961 2.6e-48 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
MGEDCBFO_00962 1.2e-18
MGEDCBFO_00963 4.2e-101 K Bacterial regulatory proteins, tetR family
MGEDCBFO_00964 9.2e-89 T Domain of unknown function (DUF4234)
MGEDCBFO_00965 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
MGEDCBFO_00966 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MGEDCBFO_00967 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MGEDCBFO_00968 1.4e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
MGEDCBFO_00969 7.3e-89 dkgB S Oxidoreductase, aldo keto reductase family protein
MGEDCBFO_00971 7.4e-288 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
MGEDCBFO_00972 0.0 pafB K WYL domain
MGEDCBFO_00973 1e-51
MGEDCBFO_00974 0.0 helY L DEAD DEAH box helicase
MGEDCBFO_00975 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MGEDCBFO_00976 6.2e-142 pgp 3.1.3.18 S HAD-hyrolase-like
MGEDCBFO_00978 3.6e-90 K Putative zinc ribbon domain
MGEDCBFO_00979 7.2e-126 S GyrI-like small molecule binding domain
MGEDCBFO_00980 1.3e-96 L DNA integration
MGEDCBFO_00982 7.3e-62
MGEDCBFO_00983 2.7e-120 K helix_turn_helix, mercury resistance
MGEDCBFO_00984 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
MGEDCBFO_00985 1.2e-141 S Bacterial protein of unknown function (DUF881)
MGEDCBFO_00986 2.6e-31 sbp S Protein of unknown function (DUF1290)
MGEDCBFO_00987 4e-173 S Bacterial protein of unknown function (DUF881)
MGEDCBFO_00988 1.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MGEDCBFO_00989 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
MGEDCBFO_00990 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
MGEDCBFO_00991 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
MGEDCBFO_00992 6.7e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MGEDCBFO_00993 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MGEDCBFO_00994 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MGEDCBFO_00995 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
MGEDCBFO_00996 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MGEDCBFO_00997 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MGEDCBFO_00998 5.7e-30
MGEDCBFO_00999 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MGEDCBFO_01000 1.1e-245
MGEDCBFO_01001 2.4e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MGEDCBFO_01002 1.9e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MGEDCBFO_01003 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MGEDCBFO_01004 2.6e-44 yajC U Preprotein translocase subunit
MGEDCBFO_01005 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MGEDCBFO_01006 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MGEDCBFO_01007 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MGEDCBFO_01008 1e-131 yebC K transcriptional regulatory protein
MGEDCBFO_01009 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
MGEDCBFO_01010 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MGEDCBFO_01011 1.7e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MGEDCBFO_01014 6.1e-272
MGEDCBFO_01018 3.7e-156 S PAC2 family
MGEDCBFO_01019 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MGEDCBFO_01020 7.1e-160 G Fructosamine kinase
MGEDCBFO_01021 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MGEDCBFO_01022 4.1e-218 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MGEDCBFO_01023 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
MGEDCBFO_01024 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MGEDCBFO_01025 1.2e-143 yoaK S Protein of unknown function (DUF1275)
MGEDCBFO_01026 4.4e-253 brnQ U Component of the transport system for branched-chain amino acids
MGEDCBFO_01027 7e-240 mepA_6 V MatE
MGEDCBFO_01028 8e-162 S Sucrose-6F-phosphate phosphohydrolase
MGEDCBFO_01029 2.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MGEDCBFO_01030 8e-33 secG U Preprotein translocase SecG subunit
MGEDCBFO_01031 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MGEDCBFO_01032 2.6e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
MGEDCBFO_01033 6.9e-173 whiA K May be required for sporulation
MGEDCBFO_01034 2.6e-177 rapZ S Displays ATPase and GTPase activities
MGEDCBFO_01035 7.5e-180 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
MGEDCBFO_01036 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MGEDCBFO_01037 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MGEDCBFO_01038 6.1e-77
MGEDCBFO_01039 1.4e-58 V MacB-like periplasmic core domain
MGEDCBFO_01041 3.6e-115 xylR K purine nucleotide biosynthetic process
MGEDCBFO_01042 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MGEDCBFO_01043 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MGEDCBFO_01044 8.9e-119
MGEDCBFO_01045 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
MGEDCBFO_01047 9.3e-161 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MGEDCBFO_01048 2.5e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MGEDCBFO_01049 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
MGEDCBFO_01050 7.2e-308 pccB I Carboxyl transferase domain
MGEDCBFO_01051 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MGEDCBFO_01052 4.2e-93 bioY S BioY family
MGEDCBFO_01053 4.4e-152 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MGEDCBFO_01054 0.0
MGEDCBFO_01055 5.9e-146 QT PucR C-terminal helix-turn-helix domain
MGEDCBFO_01056 9.5e-132 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MGEDCBFO_01057 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MGEDCBFO_01058 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MGEDCBFO_01059 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MGEDCBFO_01060 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MGEDCBFO_01061 1.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MGEDCBFO_01062 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MGEDCBFO_01063 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MGEDCBFO_01065 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
MGEDCBFO_01066 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MGEDCBFO_01068 4.6e-35
MGEDCBFO_01069 0.0 K RNA polymerase II activating transcription factor binding
MGEDCBFO_01070 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MGEDCBFO_01071 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MGEDCBFO_01072 1.3e-102 mntP P Probably functions as a manganese efflux pump
MGEDCBFO_01073 1.4e-125
MGEDCBFO_01074 2e-135 KT Transcriptional regulatory protein, C terminal
MGEDCBFO_01075 1.9e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MGEDCBFO_01076 4.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
MGEDCBFO_01077 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MGEDCBFO_01078 0.0 S domain protein
MGEDCBFO_01079 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
MGEDCBFO_01080 2.4e-90 lrp_3 K helix_turn_helix ASNC type
MGEDCBFO_01081 3e-234 E Aminotransferase class I and II
MGEDCBFO_01082 1.7e-309 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MGEDCBFO_01083 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
MGEDCBFO_01084 3.3e-52 S Protein of unknown function (DUF2469)
MGEDCBFO_01085 5.1e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
MGEDCBFO_01086 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MGEDCBFO_01087 1.1e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MGEDCBFO_01088 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MGEDCBFO_01089 6.2e-61 V ABC transporter
MGEDCBFO_01090 3.3e-59 V ABC transporter
MGEDCBFO_01091 6.9e-156 spoU 2.1.1.185 J RNA methyltransferase TrmH family
MGEDCBFO_01092 5.9e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MGEDCBFO_01093 1.3e-214 rmuC S RmuC family
MGEDCBFO_01094 9.6e-43 csoR S Metal-sensitive transcriptional repressor
MGEDCBFO_01095 0.0 pacS 3.6.3.54 P E1-E2 ATPase
MGEDCBFO_01096 0.0 ubiB S ABC1 family
MGEDCBFO_01097 3.5e-19 S granule-associated protein
MGEDCBFO_01098 2.2e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MGEDCBFO_01099 1.7e-282 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
MGEDCBFO_01100 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MGEDCBFO_01101 8.2e-252 dinF V MatE
MGEDCBFO_01102 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
MGEDCBFO_01103 1e-54 glnB K Nitrogen regulatory protein P-II
MGEDCBFO_01104 1.3e-219 amt U Ammonium Transporter Family
MGEDCBFO_01105 5.6e-204 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MGEDCBFO_01107 2.7e-116 icaR K Bacterial regulatory proteins, tetR family
MGEDCBFO_01108 1e-195 XK27_01805 M Glycosyltransferase like family 2
MGEDCBFO_01109 0.0 S Glycosyl hydrolases related to GH101 family, GH129
MGEDCBFO_01110 3.2e-305 pepD E Peptidase family C69
MGEDCBFO_01112 3.7e-19 XK26_04485 P Cobalt transport protein
MGEDCBFO_01113 1.2e-70 XK26_04485 P Cobalt transport protein
MGEDCBFO_01114 1.6e-84
MGEDCBFO_01115 0.0 V ABC transporter transmembrane region
MGEDCBFO_01116 1.8e-301 V ABC transporter, ATP-binding protein
MGEDCBFO_01117 1.3e-81 K Winged helix DNA-binding domain
MGEDCBFO_01118 3e-73 E IrrE N-terminal-like domain
MGEDCBFO_01120 1.1e-158 S Sucrose-6F-phosphate phosphohydrolase
MGEDCBFO_01121 6.6e-240 S Putative ABC-transporter type IV
MGEDCBFO_01122 2e-80
MGEDCBFO_01123 1.5e-33 Q phosphatase activity
MGEDCBFO_01124 3e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
MGEDCBFO_01125 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MGEDCBFO_01126 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MGEDCBFO_01127 2.1e-249 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MGEDCBFO_01128 4.6e-67 S haloacid dehalogenase-like hydrolase
MGEDCBFO_01129 3.6e-131 yydK K UTRA
MGEDCBFO_01130 1.3e-70 S FMN_bind
MGEDCBFO_01131 5.7e-149 macB V ABC transporter, ATP-binding protein
MGEDCBFO_01132 4.1e-202 Z012_06715 V FtsX-like permease family
MGEDCBFO_01133 9.7e-223 macB_2 V ABC transporter permease
MGEDCBFO_01134 6e-233 S Predicted membrane protein (DUF2318)
MGEDCBFO_01135 1.8e-106 tpd P Fe2+ transport protein
MGEDCBFO_01136 4.6e-308 efeU_1 P Iron permease FTR1 family
MGEDCBFO_01137 5.9e-22 G MFS/sugar transport protein
MGEDCBFO_01138 1.7e-198 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MGEDCBFO_01139 1.8e-115 S Fic/DOC family
MGEDCBFO_01140 1.1e-290 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MGEDCBFO_01141 5e-38 ptsH G PTS HPr component phosphorylation site
MGEDCBFO_01142 4.6e-197 K helix_turn _helix lactose operon repressor
MGEDCBFO_01143 1.7e-210 holB 2.7.7.7 L DNA polymerase III
MGEDCBFO_01144 2.1e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MGEDCBFO_01145 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MGEDCBFO_01146 8.8e-188 3.6.1.27 I PAP2 superfamily
MGEDCBFO_01147 0.0 vpr M PA domain
MGEDCBFO_01148 4.7e-123 yplQ S Haemolysin-III related
MGEDCBFO_01149 4.6e-232 glf 5.4.99.9 M UDP-galactopyranose mutase
MGEDCBFO_01150 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MGEDCBFO_01151 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MGEDCBFO_01152 1e-278 S Calcineurin-like phosphoesterase
MGEDCBFO_01153 6.7e-15 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MGEDCBFO_01154 1.5e-280 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MGEDCBFO_01155 1.7e-116
MGEDCBFO_01156 1.7e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MGEDCBFO_01158 1.8e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
MGEDCBFO_01159 5.3e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MGEDCBFO_01160 1.9e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MGEDCBFO_01161 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
MGEDCBFO_01162 2.4e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
MGEDCBFO_01163 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
MGEDCBFO_01164 4.8e-55 U TadE-like protein
MGEDCBFO_01165 3.2e-41 S Protein of unknown function (DUF4244)
MGEDCBFO_01166 9.5e-79 gspF NU Type II secretion system (T2SS), protein F
MGEDCBFO_01167 2.8e-120 U Type ii secretion system
MGEDCBFO_01168 3.4e-191 cpaF U Type II IV secretion system protein
MGEDCBFO_01169 1.3e-151 cpaE D bacterial-type flagellum organization
MGEDCBFO_01171 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MGEDCBFO_01172 6.3e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
MGEDCBFO_01173 5e-91
MGEDCBFO_01174 2.1e-42 cbiM P PDGLE domain
MGEDCBFO_01175 2.2e-57 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MGEDCBFO_01176 2.5e-208 S Glycosyltransferase, group 2 family protein
MGEDCBFO_01177 7.2e-275
MGEDCBFO_01178 8.7e-27 thiS 2.8.1.10 H ThiS family
MGEDCBFO_01179 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MGEDCBFO_01180 0.0 S Psort location Cytoplasmic, score 8.87
MGEDCBFO_01181 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
MGEDCBFO_01182 2.6e-245 V ABC transporter permease
MGEDCBFO_01183 4.9e-182 V ABC transporter
MGEDCBFO_01184 4.6e-137 T HD domain
MGEDCBFO_01185 8e-165 S Glutamine amidotransferase domain
MGEDCBFO_01186 0.0 kup P Transport of potassium into the cell
MGEDCBFO_01187 5.9e-185 tatD L TatD related DNase
MGEDCBFO_01188 8.3e-256 xylR 5.3.1.12 G MFS/sugar transport protein
MGEDCBFO_01190 3.4e-86 K Transcriptional regulator
MGEDCBFO_01191 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MGEDCBFO_01192 1.6e-130
MGEDCBFO_01193 8.6e-59
MGEDCBFO_01194 4.6e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MGEDCBFO_01195 2.7e-126 dedA S SNARE associated Golgi protein
MGEDCBFO_01197 1.8e-133 S HAD hydrolase, family IA, variant 3
MGEDCBFO_01198 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
MGEDCBFO_01199 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
MGEDCBFO_01200 5.2e-87 hspR K transcriptional regulator, MerR family
MGEDCBFO_01201 7.1e-173 dnaJ1 O DnaJ molecular chaperone homology domain
MGEDCBFO_01202 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MGEDCBFO_01203 0.0 dnaK O Heat shock 70 kDa protein
MGEDCBFO_01204 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
MGEDCBFO_01205 2.9e-190 K Psort location Cytoplasmic, score
MGEDCBFO_01208 1.2e-131 G Phosphoglycerate mutase family
MGEDCBFO_01209 6.2e-69 S Protein of unknown function (DUF4235)
MGEDCBFO_01210 1.2e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
MGEDCBFO_01211 1.1e-45
MGEDCBFO_01212 3.4e-111 S Phosphatidylethanolamine-binding protein
MGEDCBFO_01213 0.0 pepD E Peptidase family C69
MGEDCBFO_01214 1.4e-286 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
MGEDCBFO_01215 1.3e-62 S Macrophage migration inhibitory factor (MIF)
MGEDCBFO_01216 4.4e-97 S GtrA-like protein
MGEDCBFO_01217 6.2e-263 EGP Major facilitator Superfamily
MGEDCBFO_01218 8.1e-125 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
MGEDCBFO_01219 7.1e-143
MGEDCBFO_01220 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
MGEDCBFO_01221 1.7e-201 P NMT1/THI5 like
MGEDCBFO_01222 3.1e-124 S HAD hydrolase, family IA, variant 3
MGEDCBFO_01224 6.4e-276 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MGEDCBFO_01225 1.7e-81 S Domain of unknown function (DUF4143)
MGEDCBFO_01228 1.3e-251 S Calcineurin-like phosphoesterase
MGEDCBFO_01229 2.8e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
MGEDCBFO_01230 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MGEDCBFO_01231 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MGEDCBFO_01232 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
MGEDCBFO_01234 5.1e-180 S CAAX protease self-immunity
MGEDCBFO_01235 8e-221 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
MGEDCBFO_01236 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MGEDCBFO_01237 4.8e-225 G Transmembrane secretion effector
MGEDCBFO_01238 7.3e-132 K Bacterial regulatory proteins, tetR family
MGEDCBFO_01239 1.5e-124
MGEDCBFO_01240 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MGEDCBFO_01241 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MGEDCBFO_01242 9.8e-167 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
MGEDCBFO_01243 5.4e-187
MGEDCBFO_01244 7.9e-180
MGEDCBFO_01245 1.3e-163 trxA2 O Tetratricopeptide repeat
MGEDCBFO_01246 2.8e-119 cyaA 4.6.1.1 S CYTH
MGEDCBFO_01248 4.1e-184 K Bacterial regulatory proteins, lacI family
MGEDCBFO_01249 3.9e-16 4.2.1.68 M carboxylic acid catabolic process
MGEDCBFO_01250 9.5e-41 4.2.1.68 M Enolase C-terminal domain-like
MGEDCBFO_01251 3.4e-163 IQ KR domain
MGEDCBFO_01253 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MGEDCBFO_01254 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
MGEDCBFO_01255 2e-18 psp1 3.5.99.10 J Endoribonuclease L-PSP
MGEDCBFO_01256 2.2e-179 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MGEDCBFO_01257 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MGEDCBFO_01258 2.8e-304 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MGEDCBFO_01259 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MGEDCBFO_01260 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
MGEDCBFO_01261 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
MGEDCBFO_01262 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MGEDCBFO_01263 2e-277 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
MGEDCBFO_01264 2.1e-64
MGEDCBFO_01265 8e-58
MGEDCBFO_01266 4.9e-165 V ATPases associated with a variety of cellular activities
MGEDCBFO_01267 3.3e-256 V Efflux ABC transporter, permease protein
MGEDCBFO_01268 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
MGEDCBFO_01269 4.9e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
MGEDCBFO_01270 0.0 rne 3.1.26.12 J Ribonuclease E/G family
MGEDCBFO_01271 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
MGEDCBFO_01272 3.1e-40 rpmA J Ribosomal L27 protein
MGEDCBFO_01273 3.7e-215 K Psort location Cytoplasmic, score
MGEDCBFO_01274 3.7e-299 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MGEDCBFO_01275 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MGEDCBFO_01276 1.2e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
MGEDCBFO_01278 2.1e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MGEDCBFO_01279 1.2e-101 nusG K Participates in transcription elongation, termination and antitermination
MGEDCBFO_01280 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
MGEDCBFO_01281 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MGEDCBFO_01282 3.4e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MGEDCBFO_01283 7.5e-202 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MGEDCBFO_01284 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
MGEDCBFO_01285 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MGEDCBFO_01286 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MGEDCBFO_01287 8.8e-43
MGEDCBFO_01288 3.6e-57
MGEDCBFO_01289 5.7e-175 T Pfam Adenylate and Guanylate cyclase catalytic domain
MGEDCBFO_01290 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MGEDCBFO_01291 1.1e-79 ssb1 L Single-stranded DNA-binding protein
MGEDCBFO_01292 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MGEDCBFO_01293 1.3e-70 rplI J Binds to the 23S rRNA
MGEDCBFO_01294 2e-35 S Parallel beta-helix repeats
MGEDCBFO_01295 6.1e-67 E Domain of unknown function (DUF5011)
MGEDCBFO_01297 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MGEDCBFO_01298 3.9e-129 M Protein of unknown function (DUF3152)
MGEDCBFO_01299 9.2e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
MGEDCBFO_01300 2.2e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MGEDCBFO_01301 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
MGEDCBFO_01302 0.0 inlJ M domain protein
MGEDCBFO_01303 1e-269 M LPXTG cell wall anchor motif
MGEDCBFO_01304 1.8e-212 3.4.22.70 M Sortase family
MGEDCBFO_01305 9.8e-103 S Domain of unknown function (DUF4854)
MGEDCBFO_01306 1.3e-156 fahA Q Fumarylacetoacetate (FAA) hydrolase family
MGEDCBFO_01307 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MGEDCBFO_01308 3e-131 M Mechanosensitive ion channel
MGEDCBFO_01309 1.1e-118 K Bacterial regulatory proteins, tetR family
MGEDCBFO_01310 7.7e-241 MA20_36090 S Psort location Cytoplasmic, score 8.87
MGEDCBFO_01311 1.2e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
MGEDCBFO_01312 5.4e-66
MGEDCBFO_01314 6.7e-41 K Transcriptional regulator
MGEDCBFO_01315 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MGEDCBFO_01316 3.5e-07 S Scramblase
MGEDCBFO_01317 2.5e-33
MGEDCBFO_01322 1.3e-12 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
MGEDCBFO_01323 6.2e-235 K Helix-turn-helix XRE-family like proteins
MGEDCBFO_01324 3.8e-34 3.4.11.5 I carboxylic ester hydrolase activity
MGEDCBFO_01325 6.9e-53 relB L RelB antitoxin
MGEDCBFO_01326 3.5e-12 T Toxic component of a toxin-antitoxin (TA) module
MGEDCBFO_01327 2e-35 T Toxic component of a toxin-antitoxin (TA) module
MGEDCBFO_01328 2.5e-130 K helix_turn_helix, mercury resistance
MGEDCBFO_01329 3.3e-242 yxiO S Vacuole effluxer Atg22 like
MGEDCBFO_01331 1.1e-200 yegV G pfkB family carbohydrate kinase
MGEDCBFO_01332 1.4e-29 rpmB J Ribosomal L28 family
MGEDCBFO_01333 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
MGEDCBFO_01334 1.2e-217 steT E amino acid
MGEDCBFO_01337 0.0
MGEDCBFO_01338 4.4e-249 U Sodium:dicarboxylate symporter family
MGEDCBFO_01339 1.3e-120 rsmD 2.1.1.171 L Conserved hypothetical protein 95
MGEDCBFO_01340 6.3e-108 XK27_02070 S Nitroreductase family
MGEDCBFO_01341 2.9e-81 hsp20 O Hsp20/alpha crystallin family
MGEDCBFO_01342 4.3e-162 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MGEDCBFO_01343 6.4e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MGEDCBFO_01344 1.8e-34 CP_0960 S Belongs to the UPF0109 family
MGEDCBFO_01345 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MGEDCBFO_01346 2.9e-295 ydfD EK Alanine-glyoxylate amino-transferase
MGEDCBFO_01347 5.9e-94 argO S LysE type translocator
MGEDCBFO_01348 1.9e-222 S Endonuclease/Exonuclease/phosphatase family
MGEDCBFO_01349 8.4e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MGEDCBFO_01350 4.2e-164 P Cation efflux family
MGEDCBFO_01351 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
MGEDCBFO_01352 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
MGEDCBFO_01353 0.0 yjjK S ABC transporter
MGEDCBFO_01354 2e-58 S Protein of unknown function (DUF3039)
MGEDCBFO_01355 1.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MGEDCBFO_01356 3.6e-107
MGEDCBFO_01357 1e-113 yceD S Uncharacterized ACR, COG1399
MGEDCBFO_01358 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MGEDCBFO_01359 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MGEDCBFO_01360 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
MGEDCBFO_01361 7.6e-92 ilvN 2.2.1.6 E ACT domain
MGEDCBFO_01362 6e-15 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MGEDCBFO_01363 5.7e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MGEDCBFO_01364 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MGEDCBFO_01365 2.8e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MGEDCBFO_01366 1.1e-173 S Auxin Efflux Carrier
MGEDCBFO_01369 0.0 pgi 5.3.1.9 G Belongs to the GPI family
MGEDCBFO_01370 3.6e-189
MGEDCBFO_01372 6.9e-201
MGEDCBFO_01374 3e-120 mgtC S MgtC family
MGEDCBFO_01375 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
MGEDCBFO_01376 6.9e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
MGEDCBFO_01377 6.2e-274 abcT3 P ATPases associated with a variety of cellular activities
MGEDCBFO_01378 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
MGEDCBFO_01380 1.4e-30 K Putative sugar-binding domain
MGEDCBFO_01381 1.5e-96 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
MGEDCBFO_01382 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MGEDCBFO_01383 3.1e-158 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MGEDCBFO_01384 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MGEDCBFO_01385 6.4e-207 K helix_turn _helix lactose operon repressor
MGEDCBFO_01386 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MGEDCBFO_01387 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MGEDCBFO_01388 6.9e-110 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MGEDCBFO_01391 3.9e-245 G Glycosyl hydrolases family 43
MGEDCBFO_01392 1.3e-202 K helix_turn _helix lactose operon repressor
MGEDCBFO_01393 9.3e-11 3.2.1.14 GH18 EM Domain of unknown function (DUF5011)
MGEDCBFO_01394 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
MGEDCBFO_01395 2.9e-122 L Protein of unknown function (DUF1524)
MGEDCBFO_01396 5.5e-226 mntH P H( )-stimulated, divalent metal cation uptake system
MGEDCBFO_01397 1.5e-305 EGP Major facilitator Superfamily
MGEDCBFO_01398 1.9e-233
MGEDCBFO_01399 4e-144 cobB2 K Sir2 family
MGEDCBFO_01400 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MGEDCBFO_01401 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MGEDCBFO_01402 1.2e-145 ypfH S Phospholipase/Carboxylesterase
MGEDCBFO_01403 0.0 yjcE P Sodium/hydrogen exchanger family
MGEDCBFO_01404 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
MGEDCBFO_01405 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
MGEDCBFO_01406 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
MGEDCBFO_01408 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MGEDCBFO_01409 2e-269 KLT Domain of unknown function (DUF4032)
MGEDCBFO_01410 1.2e-144
MGEDCBFO_01411 1.3e-179 3.4.22.70 M Sortase family
MGEDCBFO_01412 1.9e-244 M LPXTG-motif cell wall anchor domain protein
MGEDCBFO_01413 0.0 S LPXTG-motif cell wall anchor domain protein
MGEDCBFO_01414 2.5e-50 L Helix-turn-helix domain
MGEDCBFO_01415 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
MGEDCBFO_01416 3.4e-174 K Psort location Cytoplasmic, score
MGEDCBFO_01417 0.0 KLT Protein tyrosine kinase
MGEDCBFO_01418 4.2e-150 O Thioredoxin
MGEDCBFO_01420 1.2e-211 S G5
MGEDCBFO_01421 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MGEDCBFO_01422 6e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MGEDCBFO_01423 6.7e-113 S LytR cell envelope-related transcriptional attenuator
MGEDCBFO_01424 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
MGEDCBFO_01425 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
MGEDCBFO_01426 0.0 M Conserved repeat domain
MGEDCBFO_01427 0.0 murJ KLT MviN-like protein
MGEDCBFO_01428 2.6e-203 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MGEDCBFO_01429 2.6e-242 parB K Belongs to the ParB family
MGEDCBFO_01430 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
MGEDCBFO_01431 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MGEDCBFO_01432 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
MGEDCBFO_01433 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
MGEDCBFO_01434 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MGEDCBFO_01435 4.1e-300 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MGEDCBFO_01436 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MGEDCBFO_01437 1.3e-238 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MGEDCBFO_01438 2e-87 S Protein of unknown function (DUF721)
MGEDCBFO_01439 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MGEDCBFO_01440 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MGEDCBFO_01441 6.7e-72 S Transmembrane domain of unknown function (DUF3566)
MGEDCBFO_01442 6.5e-14 abfA1 3.2.1.55 GH51 G arabinose metabolic process
MGEDCBFO_01443 1.2e-06 S Parallel beta-helix repeats
MGEDCBFO_01444 4.6e-187 G Glycosyl hydrolases family 43
MGEDCBFO_01445 5.5e-188 K Periplasmic binding protein domain
MGEDCBFO_01446 1.2e-227 I Serine aminopeptidase, S33
MGEDCBFO_01447 8.3e-09 K helix_turn _helix lactose operon repressor
MGEDCBFO_01449 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MGEDCBFO_01450 2.5e-124 gntR K FCD
MGEDCBFO_01451 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MGEDCBFO_01452 0.0 3.2.1.55 GH51 G arabinose metabolic process
MGEDCBFO_01455 0.0 G Glycosyl hydrolase family 20, domain 2
MGEDCBFO_01456 2.2e-188 K helix_turn _helix lactose operon repressor
MGEDCBFO_01457 8.6e-78 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MGEDCBFO_01458 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
MGEDCBFO_01459 3.6e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MGEDCBFO_01460 3.3e-135 S Protein of unknown function DUF45
MGEDCBFO_01461 3.3e-83 dps P Belongs to the Dps family
MGEDCBFO_01462 4.1e-187 yddG EG EamA-like transporter family
MGEDCBFO_01463 1.2e-241 ytfL P Transporter associated domain
MGEDCBFO_01464 1.9e-95 K helix_turn _helix lactose operon repressor
MGEDCBFO_01465 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MGEDCBFO_01466 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
MGEDCBFO_01467 0.0 trxB1 1.8.1.9 C Thioredoxin domain
MGEDCBFO_01468 1.3e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MGEDCBFO_01469 8.1e-155 yhjX EGP Major facilitator Superfamily
MGEDCBFO_01470 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MGEDCBFO_01471 0.0 yjjP S Threonine/Serine exporter, ThrE
MGEDCBFO_01472 1.4e-177 S Amidohydrolase family
MGEDCBFO_01473 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MGEDCBFO_01474 3.2e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MGEDCBFO_01475 1e-47 S Protein of unknown function (DUF3073)
MGEDCBFO_01476 3.8e-88 K LytTr DNA-binding domain
MGEDCBFO_01477 8.3e-93 T protein histidine kinase activity
MGEDCBFO_01478 2.3e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MGEDCBFO_01479 3.3e-23 I transferase activity, transferring acyl groups other than amino-acyl groups
MGEDCBFO_01480 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
MGEDCBFO_01481 2.5e-167 rfbJ M Glycosyl transferase family 2
MGEDCBFO_01482 1.8e-116 L Transposase
MGEDCBFO_01483 2.7e-138 tnp7109-2 L Transposase, Mutator family
MGEDCBFO_01484 2.8e-72 L Transposase
MGEDCBFO_01485 1.3e-207 S Acyltransferase family
MGEDCBFO_01486 4.3e-298
MGEDCBFO_01487 0.0 wbbM M Glycosyl transferase family 8
MGEDCBFO_01488 2.6e-174 ppm1 GT2 M Glycosyl transferase, family 2
MGEDCBFO_01489 0.0 M Belongs to the glycosyl hydrolase 43 family
MGEDCBFO_01490 9.8e-127 L IstB-like ATP binding protein
MGEDCBFO_01491 1.7e-253 L Transposase
MGEDCBFO_01492 1.6e-142 M Putative cell wall binding repeat 2
MGEDCBFO_01493 2.1e-120 L Protein of unknown function (DUF1524)
MGEDCBFO_01494 0.0 2.1.1.72, 3.1.4.46, 3.2.1.1 GH13 M hydrolase, family 25
MGEDCBFO_01495 1.1e-26
MGEDCBFO_01496 1.3e-142 fic D Fic/DOC family
MGEDCBFO_01497 2.4e-245 L Phage integrase family
MGEDCBFO_01498 3.6e-210 L Transposase and inactivated derivatives IS30 family
MGEDCBFO_01499 2.3e-07
MGEDCBFO_01500 1.1e-49 relB L RelB antitoxin
MGEDCBFO_01501 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
MGEDCBFO_01502 1.9e-208 E Belongs to the peptidase S1B family
MGEDCBFO_01503 6.9e-12
MGEDCBFO_01504 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MGEDCBFO_01505 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MGEDCBFO_01506 1.4e-47 S Domain of unknown function (DUF4193)
MGEDCBFO_01507 3.4e-173 S Protein of unknown function (DUF3071)
MGEDCBFO_01508 8.6e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
MGEDCBFO_01509 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MGEDCBFO_01510 0.0 lhr L DEAD DEAH box helicase
MGEDCBFO_01511 3e-25 yozG K Cro/C1-type HTH DNA-binding domain
MGEDCBFO_01512 8.6e-10 G Major Facilitator Superfamily
MGEDCBFO_01513 9.9e-277 aspA 4.3.1.1 E Fumarase C C-terminus
MGEDCBFO_01514 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MGEDCBFO_01515 5.3e-180 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MGEDCBFO_01516 1e-122
MGEDCBFO_01517 1e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
MGEDCBFO_01518 0.0 pknL 2.7.11.1 KLT PASTA
MGEDCBFO_01519 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
MGEDCBFO_01520 1.5e-109
MGEDCBFO_01521 1.5e-189 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MGEDCBFO_01522 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MGEDCBFO_01523 1.3e-109 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MGEDCBFO_01524 1e-07
MGEDCBFO_01525 7.1e-74 recX S Modulates RecA activity
MGEDCBFO_01526 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MGEDCBFO_01527 1.8e-39 S Protein of unknown function (DUF3046)
MGEDCBFO_01528 1.4e-79 K Helix-turn-helix XRE-family like proteins
MGEDCBFO_01529 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
MGEDCBFO_01530 1.9e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MGEDCBFO_01531 0.0 ftsK D FtsK SpoIIIE family protein
MGEDCBFO_01532 1.2e-137 fic D Fic/DOC family
MGEDCBFO_01533 3.1e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MGEDCBFO_01534 5.7e-280 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MGEDCBFO_01535 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
MGEDCBFO_01536 5.4e-170 ydeD EG EamA-like transporter family
MGEDCBFO_01537 6.6e-132 ybhL S Belongs to the BI1 family
MGEDCBFO_01538 3.4e-96 S Domain of unknown function (DUF5067)
MGEDCBFO_01539 3.6e-263 T Histidine kinase
MGEDCBFO_01540 1.1e-116 K helix_turn_helix, Lux Regulon
MGEDCBFO_01541 0.0 S Protein of unknown function DUF262
MGEDCBFO_01542 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MGEDCBFO_01543 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MGEDCBFO_01544 1e-237 carA 6.3.5.5 F Belongs to the CarA family
MGEDCBFO_01545 1e-87 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MGEDCBFO_01546 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MGEDCBFO_01548 2.7e-192 EGP Transmembrane secretion effector
MGEDCBFO_01549 0.0 S Esterase-like activity of phytase
MGEDCBFO_01550 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MGEDCBFO_01551 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MGEDCBFO_01552 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MGEDCBFO_01553 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MGEDCBFO_01555 5.9e-199 ltaE 4.1.2.48 E Beta-eliminating lyase
MGEDCBFO_01556 2e-227 M Glycosyl transferase 4-like domain
MGEDCBFO_01557 0.0 M Parallel beta-helix repeats
MGEDCBFO_01558 2.9e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MGEDCBFO_01559 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MGEDCBFO_01560 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
MGEDCBFO_01561 3.3e-110
MGEDCBFO_01562 2.1e-93 S Protein of unknown function (DUF4230)
MGEDCBFO_01563 4.8e-151 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
MGEDCBFO_01564 2.1e-16 K DNA-binding transcription factor activity
MGEDCBFO_01565 1.8e-68 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MGEDCBFO_01566 2e-32
MGEDCBFO_01567 8.9e-303 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
MGEDCBFO_01568 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MGEDCBFO_01569 7.6e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MGEDCBFO_01570 5e-240 purD 6.3.4.13 F Belongs to the GARS family
MGEDCBFO_01571 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MGEDCBFO_01572 1e-246 S Putative esterase
MGEDCBFO_01573 0.0 lysX S Uncharacterised conserved protein (DUF2156)
MGEDCBFO_01575 2.7e-163 P Zinc-uptake complex component A periplasmic
MGEDCBFO_01576 1e-128 S cobalamin synthesis protein
MGEDCBFO_01577 5.5e-48 rpmB J Ribosomal L28 family
MGEDCBFO_01578 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MGEDCBFO_01579 2e-42 rpmE2 J Ribosomal protein L31
MGEDCBFO_01580 8.2e-15 rpmJ J Ribosomal protein L36
MGEDCBFO_01581 2.3e-23 J Ribosomal L32p protein family
MGEDCBFO_01582 1.6e-202 ycgR S Predicted permease
MGEDCBFO_01583 2.6e-154 S TIGRFAM TIGR03943 family protein
MGEDCBFO_01584 9.8e-45
MGEDCBFO_01585 5.1e-74 zur P Belongs to the Fur family
MGEDCBFO_01586 5.3e-228 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MGEDCBFO_01587 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MGEDCBFO_01588 2.9e-179 adh3 C Zinc-binding dehydrogenase
MGEDCBFO_01589 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MGEDCBFO_01591 5.3e-44 S Memo-like protein
MGEDCBFO_01592 2.9e-229 K Putative ATP-dependent DNA helicase recG C-terminal
MGEDCBFO_01593 3.5e-160 K Helix-turn-helix domain, rpiR family
MGEDCBFO_01594 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MGEDCBFO_01595 2.3e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
MGEDCBFO_01596 2e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MGEDCBFO_01597 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
MGEDCBFO_01598 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MGEDCBFO_01599 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MGEDCBFO_01600 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MGEDCBFO_01601 1.8e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MGEDCBFO_01602 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
MGEDCBFO_01603 4.4e-109
MGEDCBFO_01604 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
MGEDCBFO_01605 1.9e-155 S Domain of unknown function (DUF4357)
MGEDCBFO_01606 5.6e-85 3.1.21.3 V Type I restriction modification DNA specificity domain
MGEDCBFO_01607 2.5e-273 3.6.4.12 K Putative DNA-binding domain
MGEDCBFO_01608 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MGEDCBFO_01609 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
MGEDCBFO_01610 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MGEDCBFO_01611 1.6e-143 S Putative ABC-transporter type IV
MGEDCBFO_01612 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MGEDCBFO_01613 4e-158 L Tetratricopeptide repeat
MGEDCBFO_01614 8.6e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MGEDCBFO_01616 4e-136 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MGEDCBFO_01617 4.4e-102
MGEDCBFO_01618 6.8e-116 trkA P TrkA-N domain
MGEDCBFO_01619 3.3e-235 trkB P Cation transport protein
MGEDCBFO_01620 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MGEDCBFO_01621 2.9e-294 recN L May be involved in recombinational repair of damaged DNA
MGEDCBFO_01622 3.4e-123 S Haloacid dehalogenase-like hydrolase
MGEDCBFO_01623 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
MGEDCBFO_01624 5e-176 V ATPases associated with a variety of cellular activities
MGEDCBFO_01625 1.7e-123 S ABC-2 family transporter protein
MGEDCBFO_01626 1.1e-116 S ABC-2 family transporter protein
MGEDCBFO_01627 1.7e-284 thrC 4.2.3.1 E Threonine synthase N terminus
MGEDCBFO_01628 9e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MGEDCBFO_01629 1.3e-91
MGEDCBFO_01630 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MGEDCBFO_01631 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MGEDCBFO_01633 2.1e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MGEDCBFO_01634 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MGEDCBFO_01635 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MGEDCBFO_01636 3.8e-78 S Bacterial PH domain
MGEDCBFO_01637 1.2e-254 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
MGEDCBFO_01639 5.8e-108
MGEDCBFO_01640 1.9e-132 C Putative TM nitroreductase
MGEDCBFO_01641 5.7e-142 yijF S Domain of unknown function (DUF1287)
MGEDCBFO_01642 2.7e-70 pdxH S Pfam:Pyridox_oxidase
MGEDCBFO_01643 3.5e-146 KT RESPONSE REGULATOR receiver
MGEDCBFO_01644 3.7e-193 V VanZ like family
MGEDCBFO_01645 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
MGEDCBFO_01646 6.4e-90 ypjC S Putative ABC-transporter type IV
MGEDCBFO_01647 8.9e-159
MGEDCBFO_01649 1.2e-97 EGP Major facilitator Superfamily
MGEDCBFO_01650 3e-28 EGP Major facilitator Superfamily
MGEDCBFO_01651 9.8e-164 rpoC M heme binding
MGEDCBFO_01652 7.3e-80 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MGEDCBFO_01653 6.5e-125
MGEDCBFO_01654 2.1e-131 S SOS response associated peptidase (SRAP)
MGEDCBFO_01655 1.2e-182 S Acetyltransferase (GNAT) domain
MGEDCBFO_01656 2.7e-38 J Aminoacyl-tRNA editing domain
MGEDCBFO_01657 1.3e-100 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
MGEDCBFO_01658 1.1e-56 K Transcriptional regulator
MGEDCBFO_01659 1.2e-97 MA20_25245 K FR47-like protein
MGEDCBFO_01660 1.5e-120 ydaF_1 J Acetyltransferase (GNAT) domain
MGEDCBFO_01661 2.4e-62 yeaO K Protein of unknown function, DUF488
MGEDCBFO_01662 2.1e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MGEDCBFO_01663 8.8e-284 S Psort location Cytoplasmic, score 8.87
MGEDCBFO_01664 2.7e-111 S Domain of unknown function (DUF4194)
MGEDCBFO_01665 0.0 S Psort location Cytoplasmic, score 8.87
MGEDCBFO_01666 4.5e-299 E Serine carboxypeptidase
MGEDCBFO_01667 4e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MGEDCBFO_01668 4.8e-171 corA P CorA-like Mg2+ transporter protein
MGEDCBFO_01669 4.1e-167 ET Bacterial periplasmic substrate-binding proteins
MGEDCBFO_01670 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MGEDCBFO_01671 2.7e-90 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
MGEDCBFO_01672 0.0 comE S Competence protein
MGEDCBFO_01673 5.3e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
MGEDCBFO_01674 1.7e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
MGEDCBFO_01675 1.9e-158 yeaZ 2.3.1.234 O Glycoprotease family
MGEDCBFO_01676 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
MGEDCBFO_01677 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MGEDCBFO_01679 2.6e-169 M Peptidase family M23
MGEDCBFO_01680 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
MGEDCBFO_01681 3.2e-276 G ABC transporter substrate-binding protein
MGEDCBFO_01682 2.2e-240 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
MGEDCBFO_01683 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
MGEDCBFO_01684 5.7e-91
MGEDCBFO_01685 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
MGEDCBFO_01686 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MGEDCBFO_01687 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
MGEDCBFO_01688 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MGEDCBFO_01689 1e-127 3.2.1.8 S alpha beta
MGEDCBFO_01690 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MGEDCBFO_01691 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MGEDCBFO_01692 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
MGEDCBFO_01693 2.3e-226 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MGEDCBFO_01694 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MGEDCBFO_01695 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MGEDCBFO_01696 7.1e-308 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MGEDCBFO_01697 1.7e-243 G Bacterial extracellular solute-binding protein
MGEDCBFO_01698 1.4e-173 G Binding-protein-dependent transport system inner membrane component
MGEDCBFO_01699 1e-168 G ABC transporter permease
MGEDCBFO_01700 9.1e-297 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MGEDCBFO_01701 1.6e-182 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MGEDCBFO_01702 6.9e-178 2.7.1.2 GK ROK family
MGEDCBFO_01703 1.9e-217 GK ROK family
MGEDCBFO_01704 2.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
MGEDCBFO_01705 3.3e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MGEDCBFO_01706 8.5e-198 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MGEDCBFO_01707 9.9e-302 ybiT S ABC transporter
MGEDCBFO_01708 2.2e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MGEDCBFO_01709 5.1e-233 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MGEDCBFO_01710 3.3e-118 K Transcriptional regulatory protein, C terminal
MGEDCBFO_01711 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MGEDCBFO_01712 1.3e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MGEDCBFO_01713 1.7e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MGEDCBFO_01714 2.9e-108 3.4.13.21 E Peptidase family S51
MGEDCBFO_01715 4.2e-135 L Phage integrase family
MGEDCBFO_01717 3.6e-219 ykiI
MGEDCBFO_01718 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MGEDCBFO_01719 1.9e-127 3.6.1.13 L NUDIX domain
MGEDCBFO_01720 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
MGEDCBFO_01721 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MGEDCBFO_01722 9.2e-120 pdtaR T Response regulator receiver domain protein
MGEDCBFO_01724 1.8e-110 aspA 3.6.1.13 L NUDIX domain
MGEDCBFO_01725 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
MGEDCBFO_01726 1.3e-179 terC P Integral membrane protein, TerC family
MGEDCBFO_01727 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MGEDCBFO_01728 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MGEDCBFO_01729 3.3e-243 rpsA J Ribosomal protein S1
MGEDCBFO_01730 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MGEDCBFO_01731 7.4e-173 P Zinc-uptake complex component A periplasmic
MGEDCBFO_01732 1.8e-164 znuC P ATPases associated with a variety of cellular activities
MGEDCBFO_01733 4.3e-139 znuB U ABC 3 transport family
MGEDCBFO_01734 1.2e-82 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MGEDCBFO_01735 5.1e-102 carD K CarD-like/TRCF domain
MGEDCBFO_01736 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MGEDCBFO_01737 1.9e-127 T Response regulator receiver domain protein
MGEDCBFO_01738 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MGEDCBFO_01739 3.6e-72 rulA 3.4.21.88 KT Peptidase S24-like
MGEDCBFO_01740 7.7e-129 ctsW S Phosphoribosyl transferase domain
MGEDCBFO_01741 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
MGEDCBFO_01742 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
MGEDCBFO_01743 1.2e-264
MGEDCBFO_01744 0.0 S Glycosyl transferase, family 2
MGEDCBFO_01745 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MGEDCBFO_01746 2.4e-270 K Cell envelope-related transcriptional attenuator domain
MGEDCBFO_01747 0.0 D FtsK/SpoIIIE family
MGEDCBFO_01748 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MGEDCBFO_01749 7.3e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MGEDCBFO_01750 2e-142 yplQ S Haemolysin-III related
MGEDCBFO_01751 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MGEDCBFO_01752 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
MGEDCBFO_01753 7.9e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
MGEDCBFO_01754 4.7e-97
MGEDCBFO_01756 1.2e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MGEDCBFO_01757 4.4e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
MGEDCBFO_01758 9.4e-101 divIC D Septum formation initiator
MGEDCBFO_01759 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MGEDCBFO_01760 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
MGEDCBFO_01761 2.2e-298 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
MGEDCBFO_01762 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MGEDCBFO_01763 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MGEDCBFO_01764 3.9e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
MGEDCBFO_01765 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
MGEDCBFO_01766 3.6e-151 GM ABC-2 type transporter
MGEDCBFO_01767 4.3e-197 GM GDP-mannose 4,6 dehydratase
MGEDCBFO_01768 1.8e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MGEDCBFO_01771 2.9e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
MGEDCBFO_01772 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MGEDCBFO_01773 2.1e-207 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MGEDCBFO_01774 0.0 S Uncharacterised protein family (UPF0182)
MGEDCBFO_01775 6.7e-232 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
MGEDCBFO_01776 7.6e-197
MGEDCBFO_01777 1.9e-152 ytrE V ATPases associated with a variety of cellular activities
MGEDCBFO_01778 3.7e-191 V N-Acetylmuramoyl-L-alanine amidase
MGEDCBFO_01779 1.2e-258 argE E Peptidase dimerisation domain
MGEDCBFO_01780 4.2e-104 S Protein of unknown function (DUF3043)
MGEDCBFO_01781 3.2e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MGEDCBFO_01782 9.4e-144 S Domain of unknown function (DUF4191)
MGEDCBFO_01783 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
MGEDCBFO_01784 1.3e-18
MGEDCBFO_01786 5.1e-19
MGEDCBFO_01789 8.8e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MGEDCBFO_01790 5.7e-211 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MGEDCBFO_01791 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MGEDCBFO_01792 0.0 S Tetratricopeptide repeat
MGEDCBFO_01793 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MGEDCBFO_01794 4.9e-69 2.8.2.22 S Arylsulfotransferase Ig-like domain
MGEDCBFO_01795 2.4e-139 bioM P ATPases associated with a variety of cellular activities
MGEDCBFO_01796 2e-213 E Aminotransferase class I and II
MGEDCBFO_01797 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
MGEDCBFO_01799 1.1e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MGEDCBFO_01800 0.0 ecfA GP ABC transporter, ATP-binding protein
MGEDCBFO_01801 5.7e-256 EGP Major facilitator Superfamily
MGEDCBFO_01803 2.2e-257 rarA L Recombination factor protein RarA
MGEDCBFO_01804 0.0 L DEAD DEAH box helicase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)