ORF_ID e_value Gene_name EC_number CAZy COGs Description
MEIPOLNH_00001 1.3e-70 3.1.21.3 V Type I restriction modification DNA specificity domain
MEIPOLNH_00002 8e-280 3.6.4.12 K Putative DNA-binding domain
MEIPOLNH_00003 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MEIPOLNH_00004 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
MEIPOLNH_00005 6.1e-108 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MEIPOLNH_00006 2.9e-142 S Putative ABC-transporter type IV
MEIPOLNH_00007 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEIPOLNH_00008 3.6e-159 L Tetratricopeptide repeat
MEIPOLNH_00009 2.3e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MEIPOLNH_00011 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MEIPOLNH_00012 9.8e-102
MEIPOLNH_00013 6.8e-116 trkA P TrkA-N domain
MEIPOLNH_00014 3.3e-235 trkB P Cation transport protein
MEIPOLNH_00015 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEIPOLNH_00016 1.1e-293 recN L May be involved in recombinational repair of damaged DNA
MEIPOLNH_00017 8.9e-124 S Haloacid dehalogenase-like hydrolase
MEIPOLNH_00018 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
MEIPOLNH_00019 4.5e-177 V ATPases associated with a variety of cellular activities
MEIPOLNH_00020 3.7e-126 S ABC-2 family transporter protein
MEIPOLNH_00021 8.1e-123 S ABC-2 family transporter protein
MEIPOLNH_00022 5.1e-284 thrC 4.2.3.1 E Threonine synthase N terminus
MEIPOLNH_00023 5.8e-236 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEIPOLNH_00024 2.6e-92
MEIPOLNH_00025 8.1e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEIPOLNH_00026 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEIPOLNH_00028 7.8e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEIPOLNH_00029 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEIPOLNH_00030 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MEIPOLNH_00031 3.8e-78 S Bacterial PH domain
MEIPOLNH_00032 1.2e-254 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
MEIPOLNH_00034 5.8e-108
MEIPOLNH_00035 1.9e-132 C Putative TM nitroreductase
MEIPOLNH_00036 2.7e-139 yijF S Domain of unknown function (DUF1287)
MEIPOLNH_00037 2.7e-70 pdxH S Pfam:Pyridox_oxidase
MEIPOLNH_00038 1.3e-145 KT RESPONSE REGULATOR receiver
MEIPOLNH_00039 2.8e-193 V VanZ like family
MEIPOLNH_00040 3.7e-108 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
MEIPOLNH_00041 1.1e-60 ypjC S Putative ABC-transporter type IV
MEIPOLNH_00042 4.5e-155
MEIPOLNH_00044 1.3e-117 EGP Major facilitator Superfamily
MEIPOLNH_00045 4.1e-162 rpoC M heme binding
MEIPOLNH_00046 2.4e-78 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEIPOLNH_00047 3.8e-64
MEIPOLNH_00048 6.1e-131 S SOS response associated peptidase (SRAP)
MEIPOLNH_00049 2.2e-76 qseC 2.7.13.3 T Histidine kinase
MEIPOLNH_00050 1.9e-183 S Acetyltransferase (GNAT) domain
MEIPOLNH_00051 2.7e-38 J Aminoacyl-tRNA editing domain
MEIPOLNH_00052 1.3e-100 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
MEIPOLNH_00053 5e-57 K Transcriptional regulator
MEIPOLNH_00054 2.5e-121 ydaF_1 J Acetyltransferase (GNAT) domain
MEIPOLNH_00055 4.4e-64 yeaO K Protein of unknown function, DUF488
MEIPOLNH_00056 3.7e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MEIPOLNH_00057 5.7e-283 S Psort location Cytoplasmic, score 8.87
MEIPOLNH_00058 2.5e-112 S Domain of unknown function (DUF4194)
MEIPOLNH_00059 0.0 S Psort location Cytoplasmic, score 8.87
MEIPOLNH_00060 4.5e-299 E Serine carboxypeptidase
MEIPOLNH_00061 4e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MEIPOLNH_00062 4.8e-171 corA P CorA-like Mg2+ transporter protein
MEIPOLNH_00063 2.9e-168 ET Bacterial periplasmic substrate-binding proteins
MEIPOLNH_00064 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEIPOLNH_00065 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
MEIPOLNH_00066 0.0 comE S Competence protein
MEIPOLNH_00067 8.1e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
MEIPOLNH_00068 1.7e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
MEIPOLNH_00069 2.3e-159 yeaZ 2.3.1.234 O Glycoprotease family
MEIPOLNH_00070 1.2e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
MEIPOLNH_00071 1.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEIPOLNH_00073 9.1e-169 M Peptidase family M23
MEIPOLNH_00074 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
MEIPOLNH_00075 3.3e-273 G ABC transporter substrate-binding protein
MEIPOLNH_00076 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
MEIPOLNH_00077 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
MEIPOLNH_00078 5.7e-91
MEIPOLNH_00079 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
MEIPOLNH_00080 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEIPOLNH_00081 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
MEIPOLNH_00082 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEIPOLNH_00083 1.8e-127 3.2.1.8 S alpha beta
MEIPOLNH_00084 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MEIPOLNH_00085 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEIPOLNH_00086 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
MEIPOLNH_00087 8.3e-229 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MEIPOLNH_00088 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MEIPOLNH_00089 2e-73 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MEIPOLNH_00090 6.2e-304 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MEIPOLNH_00091 6.5e-243 G Bacterial extracellular solute-binding protein
MEIPOLNH_00092 1.4e-173 G Binding-protein-dependent transport system inner membrane component
MEIPOLNH_00093 9.4e-167 G ABC transporter permease
MEIPOLNH_00094 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MEIPOLNH_00095 6.9e-178 2.7.1.2 GK ROK family
MEIPOLNH_00096 6.4e-218 GK ROK family
MEIPOLNH_00097 4e-206 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
MEIPOLNH_00098 2.8e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MEIPOLNH_00099 4.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MEIPOLNH_00100 8.9e-303 ybiT S ABC transporter
MEIPOLNH_00101 3.2e-110 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MEIPOLNH_00102 2.3e-233 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MEIPOLNH_00103 3.3e-118 K Transcriptional regulatory protein, C terminal
MEIPOLNH_00105 1.4e-58 V MacB-like periplasmic core domain
MEIPOLNH_00106 6.1e-77
MEIPOLNH_00107 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEIPOLNH_00108 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEIPOLNH_00109 7.5e-180 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
MEIPOLNH_00110 2.6e-177 rapZ S Displays ATPase and GTPase activities
MEIPOLNH_00111 6.9e-173 whiA K May be required for sporulation
MEIPOLNH_00112 2.6e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
MEIPOLNH_00113 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEIPOLNH_00114 8e-33 secG U Preprotein translocase SecG subunit
MEIPOLNH_00115 2.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MEIPOLNH_00116 8e-162 S Sucrose-6F-phosphate phosphohydrolase
MEIPOLNH_00117 7e-240 mepA_6 V MatE
MEIPOLNH_00118 4.4e-253 brnQ U Component of the transport system for branched-chain amino acids
MEIPOLNH_00119 1.2e-143 yoaK S Protein of unknown function (DUF1275)
MEIPOLNH_00120 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MEIPOLNH_00121 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
MEIPOLNH_00122 4.1e-218 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEIPOLNH_00123 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEIPOLNH_00124 7.1e-160 G Fructosamine kinase
MEIPOLNH_00125 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MEIPOLNH_00126 3.7e-156 S PAC2 family
MEIPOLNH_00130 6.1e-272
MEIPOLNH_00133 1.7e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEIPOLNH_00134 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEIPOLNH_00135 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
MEIPOLNH_00136 1e-131 yebC K transcriptional regulatory protein
MEIPOLNH_00137 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MEIPOLNH_00139 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEIPOLNH_00140 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEIPOLNH_00141 2.6e-44 yajC U Preprotein translocase subunit
MEIPOLNH_00142 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEIPOLNH_00143 1.1e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MEIPOLNH_00144 2.4e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MEIPOLNH_00145 3.2e-245
MEIPOLNH_00146 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MEIPOLNH_00147 5.7e-30
MEIPOLNH_00148 4.1e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MEIPOLNH_00149 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEIPOLNH_00150 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
MEIPOLNH_00151 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MEIPOLNH_00152 3.5e-160 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MEIPOLNH_00153 7.7e-188 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEIPOLNH_00154 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
MEIPOLNH_00155 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
MEIPOLNH_00156 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
MEIPOLNH_00157 1e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEIPOLNH_00158 1.2e-172 S Bacterial protein of unknown function (DUF881)
MEIPOLNH_00159 4.5e-31 sbp S Protein of unknown function (DUF1290)
MEIPOLNH_00160 2.5e-139 S Bacterial protein of unknown function (DUF881)
MEIPOLNH_00161 9.6e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
MEIPOLNH_00162 1.8e-119 K helix_turn_helix, mercury resistance
MEIPOLNH_00163 4.3e-62
MEIPOLNH_00165 3.4e-92 L DNA integration
MEIPOLNH_00166 2.1e-125 S GyrI-like small molecule binding domain
MEIPOLNH_00167 1.2e-88 K Putative zinc ribbon domain
MEIPOLNH_00169 6.2e-142 pgp 3.1.3.18 S HAD-hyrolase-like
MEIPOLNH_00170 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MEIPOLNH_00171 0.0 helY L DEAD DEAH box helicase
MEIPOLNH_00172 1e-51
MEIPOLNH_00173 0.0 pafB K WYL domain
MEIPOLNH_00174 7.4e-288 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
MEIPOLNH_00176 5.1e-90 dkgB S Oxidoreductase, aldo keto reductase family protein
MEIPOLNH_00177 1.4e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
MEIPOLNH_00178 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEIPOLNH_00179 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MEIPOLNH_00180 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
MEIPOLNH_00181 7.3e-86 T Domain of unknown function (DUF4234)
MEIPOLNH_00182 1.2e-100 K Bacterial regulatory proteins, tetR family
MEIPOLNH_00183 1.1e-19
MEIPOLNH_00184 3.5e-45 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
MEIPOLNH_00185 6.4e-41 K Helix-turn-helix
MEIPOLNH_00186 8.5e-223 hipA 2.7.11.1 S HipA N-terminal domain
MEIPOLNH_00187 3.3e-67 4.1.1.44 S Cupin domain
MEIPOLNH_00188 2.2e-174 S Membrane transport protein
MEIPOLNH_00189 1e-93 laaE K Transcriptional regulator PadR-like family
MEIPOLNH_00190 1.1e-132 magIII L endonuclease III
MEIPOLNH_00191 2.1e-131 S Enoyl-(Acyl carrier protein) reductase
MEIPOLNH_00192 4.4e-242 vbsD V MatE
MEIPOLNH_00193 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MEIPOLNH_00194 9.1e-16 KLT Protein tyrosine kinase
MEIPOLNH_00195 1.3e-16 K Psort location Cytoplasmic, score
MEIPOLNH_00196 4.8e-141
MEIPOLNH_00197 1.2e-194 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MEIPOLNH_00198 2.8e-09 K MerR family regulatory protein
MEIPOLNH_00199 6.5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEIPOLNH_00200 1.4e-178 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEIPOLNH_00201 7.7e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MEIPOLNH_00202 6.8e-181 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
MEIPOLNH_00203 3.8e-281 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEIPOLNH_00204 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MEIPOLNH_00205 6.4e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MEIPOLNH_00206 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MEIPOLNH_00208 1.6e-162 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
MEIPOLNH_00209 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MEIPOLNH_00210 2.6e-100 sixA T Phosphoglycerate mutase family
MEIPOLNH_00211 6.3e-207 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MEIPOLNH_00212 2e-177 I alpha/beta hydrolase fold
MEIPOLNH_00213 5.8e-25 rarD S Rard protein
MEIPOLNH_00214 1.1e-89 rarD 3.4.17.13 E Rard protein
MEIPOLNH_00215 5e-30
MEIPOLNH_00216 9.7e-191 mcrB L Restriction endonuclease
MEIPOLNH_00218 7.5e-95
MEIPOLNH_00219 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
MEIPOLNH_00220 0.0 thiN 2.7.6.2 H PglZ domain
MEIPOLNH_00221 2.4e-257 lexA 3.6.4.12 K Putative DNA-binding domain
MEIPOLNH_00222 0.0 K SIR2-like domain
MEIPOLNH_00223 0.0 LV DNA restriction-modification system
MEIPOLNH_00224 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
MEIPOLNH_00225 1.2e-134 S Domain of unknown function (DUF1788)
MEIPOLNH_00226 3.3e-95 S Putative inner membrane protein (DUF1819)
MEIPOLNH_00227 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEIPOLNH_00228 8.5e-113 S Sel1-like repeats.
MEIPOLNH_00229 6.3e-160 ybeM S Carbon-nitrogen hydrolase
MEIPOLNH_00230 3.8e-182 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
MEIPOLNH_00231 3.3e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
MEIPOLNH_00232 3.6e-82
MEIPOLNH_00233 5e-303 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MEIPOLNH_00234 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
MEIPOLNH_00235 0.0 tetP J Elongation factor G, domain IV
MEIPOLNH_00236 1.5e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
MEIPOLNH_00237 1.2e-12 S Membrane
MEIPOLNH_00238 3.3e-245 hemN H Involved in the biosynthesis of porphyrin-containing compound
MEIPOLNH_00239 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEIPOLNH_00240 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
MEIPOLNH_00241 4.4e-135 S UPF0126 domain
MEIPOLNH_00242 1e-148 3.1.4.37 T RNA ligase
MEIPOLNH_00243 4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
MEIPOLNH_00244 3.9e-92 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MEIPOLNH_00245 2.8e-190 S alpha beta
MEIPOLNH_00246 2e-232 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MEIPOLNH_00247 5.7e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
MEIPOLNH_00248 1.8e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
MEIPOLNH_00249 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MEIPOLNH_00250 1.5e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEIPOLNH_00251 1.6e-250 corC S CBS domain
MEIPOLNH_00252 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEIPOLNH_00253 3.4e-197 phoH T PhoH-like protein
MEIPOLNH_00254 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
MEIPOLNH_00255 6.1e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEIPOLNH_00257 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
MEIPOLNH_00258 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MEIPOLNH_00259 1.1e-106 yitW S Iron-sulfur cluster assembly protein
MEIPOLNH_00260 1.2e-100 iscU C SUF system FeS assembly protein, NifU family
MEIPOLNH_00261 1.7e-240 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEIPOLNH_00262 1.4e-144 sufC O FeS assembly ATPase SufC
MEIPOLNH_00263 2.6e-233 sufD O FeS assembly protein SufD
MEIPOLNH_00264 1.4e-289 sufB O FeS assembly protein SufB
MEIPOLNH_00265 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEIPOLNH_00266 1.1e-16 3.4.22.70 M Sortase family
MEIPOLNH_00267 1.7e-120 K helix_turn_helix, Lux Regulon
MEIPOLNH_00268 1.8e-16
MEIPOLNH_00269 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MEIPOLNH_00270 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MEIPOLNH_00271 1.7e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MEIPOLNH_00272 2.2e-47 3.4.23.43 S Type IV leader peptidase family
MEIPOLNH_00273 1.3e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MEIPOLNH_00274 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEIPOLNH_00275 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEIPOLNH_00276 1.1e-36
MEIPOLNH_00277 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
MEIPOLNH_00278 3.6e-134 pgm3 G Phosphoglycerate mutase family
MEIPOLNH_00279 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
MEIPOLNH_00280 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEIPOLNH_00281 1.9e-128 lolD V ABC transporter
MEIPOLNH_00282 5.5e-212 V FtsX-like permease family
MEIPOLNH_00283 8.2e-64 S Domain of unknown function (DUF4418)
MEIPOLNH_00284 0.0 pcrA 3.6.4.12 L DNA helicase
MEIPOLNH_00285 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
MEIPOLNH_00286 1.9e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEIPOLNH_00287 4.1e-240 pbuX F Permease family
MEIPOLNH_00289 8.1e-47 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEIPOLNH_00290 8.3e-108 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEIPOLNH_00292 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
MEIPOLNH_00293 9e-40
MEIPOLNH_00294 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
MEIPOLNH_00295 1.7e-181 tnp7109-21 L Integrase core domain
MEIPOLNH_00296 8.6e-48 L Transposase
MEIPOLNH_00297 1.2e-64 D MobA/MobL family
MEIPOLNH_00298 4.4e-85
MEIPOLNH_00300 4.3e-205 L Transposase and inactivated derivatives IS30 family
MEIPOLNH_00301 1.7e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MEIPOLNH_00302 8.5e-249 V ABC-2 family transporter protein
MEIPOLNH_00303 1.7e-224 V ABC-2 family transporter protein
MEIPOLNH_00304 2.9e-179 V ATPases associated with a variety of cellular activities
MEIPOLNH_00305 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MEIPOLNH_00306 9.2e-234 T Histidine kinase
MEIPOLNH_00307 3.1e-119 K helix_turn_helix, Lux Regulon
MEIPOLNH_00308 1.1e-115 MA20_27875 P Protein of unknown function DUF47
MEIPOLNH_00309 4.8e-188 pit P Phosphate transporter family
MEIPOLNH_00310 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MEIPOLNH_00311 3.3e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MEIPOLNH_00312 4e-181 L HTH-like domain
MEIPOLNH_00313 2.6e-112 bepIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
MEIPOLNH_00314 4.5e-85
MEIPOLNH_00315 1.9e-87 L Transposase
MEIPOLNH_00316 2.1e-25 L Transposase
MEIPOLNH_00317 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MEIPOLNH_00318 1.3e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEIPOLNH_00319 1.7e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEIPOLNH_00320 2.9e-108 3.4.13.21 E Peptidase family S51
MEIPOLNH_00321 4.2e-135 L Phage integrase family
MEIPOLNH_00323 3.6e-219 ykiI
MEIPOLNH_00324 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MEIPOLNH_00325 1.9e-127 3.6.1.13 L NUDIX domain
MEIPOLNH_00326 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
MEIPOLNH_00327 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEIPOLNH_00328 9.2e-120 pdtaR T Response regulator receiver domain protein
MEIPOLNH_00330 1.8e-110 aspA 3.6.1.13 L NUDIX domain
MEIPOLNH_00331 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
MEIPOLNH_00332 1.3e-179 terC P Integral membrane protein, TerC family
MEIPOLNH_00333 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEIPOLNH_00334 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEIPOLNH_00335 3.3e-243 rpsA J Ribosomal protein S1
MEIPOLNH_00336 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEIPOLNH_00337 1.4e-171 P Zinc-uptake complex component A periplasmic
MEIPOLNH_00338 5.3e-164 znuC P ATPases associated with a variety of cellular activities
MEIPOLNH_00339 4.3e-139 znuB U ABC 3 transport family
MEIPOLNH_00340 4.2e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MEIPOLNH_00341 5.1e-102 carD K CarD-like/TRCF domain
MEIPOLNH_00342 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MEIPOLNH_00343 1.9e-127 T Response regulator receiver domain protein
MEIPOLNH_00344 1.1e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEIPOLNH_00345 2.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
MEIPOLNH_00346 1.7e-128 ctsW S Phosphoribosyl transferase domain
MEIPOLNH_00347 1.4e-155 cof 5.2.1.8 T Eukaryotic phosphomannomutase
MEIPOLNH_00348 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
MEIPOLNH_00349 1.2e-264
MEIPOLNH_00350 0.0 S Glycosyl transferase, family 2
MEIPOLNH_00351 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MEIPOLNH_00352 1.5e-267 K Cell envelope-related transcriptional attenuator domain
MEIPOLNH_00353 0.0 D FtsK/SpoIIIE family
MEIPOLNH_00354 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MEIPOLNH_00355 2.1e-285 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEIPOLNH_00356 4.4e-142 yplQ S Haemolysin-III related
MEIPOLNH_00357 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEIPOLNH_00358 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
MEIPOLNH_00359 7.9e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
MEIPOLNH_00360 4.7e-97
MEIPOLNH_00362 1.2e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MEIPOLNH_00363 4.4e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
MEIPOLNH_00364 9.4e-101 divIC D Septum formation initiator
MEIPOLNH_00365 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEIPOLNH_00366 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
MEIPOLNH_00367 2.2e-298 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
MEIPOLNH_00368 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEIPOLNH_00369 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEIPOLNH_00370 2.7e-97 2.3.1.183 M Acetyltransferase (GNAT) domain
MEIPOLNH_00371 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
MEIPOLNH_00372 3.6e-151 GM ABC-2 type transporter
MEIPOLNH_00373 4.3e-197 GM GDP-mannose 4,6 dehydratase
MEIPOLNH_00374 1.8e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MEIPOLNH_00377 3.5e-219 I transferase activity, transferring acyl groups other than amino-acyl groups
MEIPOLNH_00378 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEIPOLNH_00379 8.1e-207 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEIPOLNH_00380 0.0 S Uncharacterised protein family (UPF0182)
MEIPOLNH_00381 2.3e-232 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
MEIPOLNH_00382 3.8e-196
MEIPOLNH_00383 4.8e-143 ytrE V ATPases associated with a variety of cellular activities
MEIPOLNH_00384 8.3e-191 V N-Acetylmuramoyl-L-alanine amidase
MEIPOLNH_00385 1.2e-258 argE E Peptidase dimerisation domain
MEIPOLNH_00386 4.2e-104 S Protein of unknown function (DUF3043)
MEIPOLNH_00387 3.2e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MEIPOLNH_00388 9.4e-144 S Domain of unknown function (DUF4191)
MEIPOLNH_00389 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
MEIPOLNH_00390 1.3e-18
MEIPOLNH_00392 5.1e-19
MEIPOLNH_00395 8.8e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MEIPOLNH_00396 5.7e-211 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MEIPOLNH_00397 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEIPOLNH_00398 0.0 S Tetratricopeptide repeat
MEIPOLNH_00399 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEIPOLNH_00400 4.9e-69 2.8.2.22 S Arylsulfotransferase Ig-like domain
MEIPOLNH_00401 4e-139 bioM P ATPases associated with a variety of cellular activities
MEIPOLNH_00402 3.9e-212 E Aminotransferase class I and II
MEIPOLNH_00403 1.7e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
MEIPOLNH_00404 1.3e-103 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEIPOLNH_00405 0.0 ecfA GP ABC transporter, ATP-binding protein
MEIPOLNH_00406 5.2e-257 EGP Major facilitator Superfamily
MEIPOLNH_00408 8.5e-257 rarA L Recombination factor protein RarA
MEIPOLNH_00409 0.0 L DEAD DEAH box helicase
MEIPOLNH_00410 7.8e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
MEIPOLNH_00411 4.8e-199 gluD E Binding-protein-dependent transport system inner membrane component
MEIPOLNH_00412 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
MEIPOLNH_00413 9.5e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
MEIPOLNH_00414 3.6e-140 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
MEIPOLNH_00415 8.2e-93 S Aminoacyl-tRNA editing domain
MEIPOLNH_00416 3.3e-81 K helix_turn_helix, Lux Regulon
MEIPOLNH_00417 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MEIPOLNH_00418 2.1e-260 hisS 6.1.1.21 J Histidyl-tRNA synthetase
MEIPOLNH_00419 5.1e-217 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
MEIPOLNH_00420 0.0 clpC O ATPase family associated with various cellular activities (AAA)
MEIPOLNH_00421 1.4e-184 uspA T Belongs to the universal stress protein A family
MEIPOLNH_00422 3.6e-191 S Protein of unknown function (DUF3027)
MEIPOLNH_00423 1e-66 cspB K 'Cold-shock' DNA-binding domain
MEIPOLNH_00424 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEIPOLNH_00425 1.4e-133 KT Response regulator receiver domain protein
MEIPOLNH_00426 1.2e-173
MEIPOLNH_00427 1.7e-10 S Proteins of 100 residues with WXG
MEIPOLNH_00428 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEIPOLNH_00429 1.4e-30 cspA K 'Cold-shock' DNA-binding domain
MEIPOLNH_00430 1.4e-69 S LytR cell envelope-related transcriptional attenuator
MEIPOLNH_00431 2e-143 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEIPOLNH_00432 2.3e-196 moxR S ATPase family associated with various cellular activities (AAA)
MEIPOLNH_00433 7.2e-178 S Protein of unknown function DUF58
MEIPOLNH_00434 6.4e-94
MEIPOLNH_00435 4.4e-189 S von Willebrand factor (vWF) type A domain
MEIPOLNH_00436 1.4e-147 S von Willebrand factor (vWF) type A domain
MEIPOLNH_00437 2.7e-74
MEIPOLNH_00439 2.9e-290 S PGAP1-like protein
MEIPOLNH_00440 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
MEIPOLNH_00441 0.0 S Lysylphosphatidylglycerol synthase TM region
MEIPOLNH_00442 8.1e-42 hup L Belongs to the bacterial histone-like protein family
MEIPOLNH_00443 2.2e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MEIPOLNH_00444 9.2e-11 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MEIPOLNH_00445 2.2e-156 hisN 3.1.3.25 G Inositol monophosphatase family
MEIPOLNH_00446 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
MEIPOLNH_00447 0.0 arc O AAA ATPase forming ring-shaped complexes
MEIPOLNH_00449 1.6e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
MEIPOLNH_00450 5.6e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEIPOLNH_00451 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MEIPOLNH_00452 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEIPOLNH_00453 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEIPOLNH_00454 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEIPOLNH_00455 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
MEIPOLNH_00456 1.1e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MEIPOLNH_00458 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MEIPOLNH_00459 0.0 ctpE P E1-E2 ATPase
MEIPOLNH_00460 2e-109
MEIPOLNH_00461 3.2e-247 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEIPOLNH_00462 3.7e-129 S Protein of unknown function (DUF3159)
MEIPOLNH_00463 2.1e-138 S Protein of unknown function (DUF3710)
MEIPOLNH_00464 1.8e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
MEIPOLNH_00465 5.2e-262 pepC 3.4.22.40 E Peptidase C1-like family
MEIPOLNH_00466 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
MEIPOLNH_00467 0.0 oppD P Belongs to the ABC transporter superfamily
MEIPOLNH_00468 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
MEIPOLNH_00469 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
MEIPOLNH_00470 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MEIPOLNH_00471 7.3e-42
MEIPOLNH_00472 1.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
MEIPOLNH_00473 5.5e-197 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
MEIPOLNH_00474 5.5e-92
MEIPOLNH_00475 0.0 typA T Elongation factor G C-terminus
MEIPOLNH_00476 1.4e-237 iscS1 2.8.1.7 E Aminotransferase class-V
MEIPOLNH_00477 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
MEIPOLNH_00478 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MEIPOLNH_00479 9.8e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MEIPOLNH_00480 1.1e-149 nrtR 3.6.1.55 F NUDIX hydrolase
MEIPOLNH_00481 5.4e-113 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEIPOLNH_00482 3.2e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEIPOLNH_00483 7e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MEIPOLNH_00484 2.9e-179 xerD D recombinase XerD
MEIPOLNH_00485 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEIPOLNH_00486 2.1e-25 rpmI J Ribosomal protein L35
MEIPOLNH_00487 2.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEIPOLNH_00488 1.9e-07 S Spermine/spermidine synthase domain
MEIPOLNH_00489 8e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
MEIPOLNH_00490 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEIPOLNH_00491 2.4e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEIPOLNH_00493 2e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MEIPOLNH_00494 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
MEIPOLNH_00495 2e-64
MEIPOLNH_00496 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
MEIPOLNH_00497 1.4e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEIPOLNH_00498 5.7e-191 V Acetyltransferase (GNAT) domain
MEIPOLNH_00499 6.4e-229 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
MEIPOLNH_00500 2.8e-243 yxbA 6.3.1.12 S ATP-grasp
MEIPOLNH_00501 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
MEIPOLNH_00502 0.0 smc D Required for chromosome condensation and partitioning
MEIPOLNH_00503 8e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
MEIPOLNH_00505 9.6e-97 3.6.1.55 F NUDIX domain
MEIPOLNH_00506 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
MEIPOLNH_00507 0.0 P Belongs to the ABC transporter superfamily
MEIPOLNH_00508 1.9e-190 dppC EP Binding-protein-dependent transport system inner membrane component
MEIPOLNH_00509 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
MEIPOLNH_00510 3.7e-304 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
MEIPOLNH_00511 6.2e-243 nagA 3.5.1.25 G Amidohydrolase family
MEIPOLNH_00512 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEIPOLNH_00513 7e-217 GK ROK family
MEIPOLNH_00514 2.9e-131 cutC P Participates in the control of copper homeostasis
MEIPOLNH_00515 2e-222 GK ROK family
MEIPOLNH_00516 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
MEIPOLNH_00517 1.3e-235 G Major Facilitator Superfamily
MEIPOLNH_00518 6.6e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEIPOLNH_00520 1.3e-37
MEIPOLNH_00521 3.9e-160 ftsQ 6.3.2.4 D Cell division protein FtsQ
MEIPOLNH_00522 6.1e-296 murC 6.3.2.8 M Belongs to the MurCDEF family
MEIPOLNH_00523 6.5e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEIPOLNH_00524 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
MEIPOLNH_00525 7.8e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEIPOLNH_00526 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEIPOLNH_00527 3.1e-284 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEIPOLNH_00528 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEIPOLNH_00529 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
MEIPOLNH_00530 2.5e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MEIPOLNH_00531 1.1e-193 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEIPOLNH_00532 1.3e-90 mraZ K Belongs to the MraZ family
MEIPOLNH_00533 0.0 L DNA helicase
MEIPOLNH_00534 3.2e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MEIPOLNH_00535 1.1e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEIPOLNH_00536 1.5e-43 M Lysin motif
MEIPOLNH_00537 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEIPOLNH_00538 1.2e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEIPOLNH_00539 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
MEIPOLNH_00540 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEIPOLNH_00541 2.6e-169
MEIPOLNH_00542 4.1e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
MEIPOLNH_00543 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
MEIPOLNH_00544 1.3e-172 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MEIPOLNH_00545 1e-60 EGP Major facilitator Superfamily
MEIPOLNH_00546 3.2e-245 S Domain of unknown function (DUF5067)
MEIPOLNH_00547 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
MEIPOLNH_00548 4.9e-284 S Uncharacterized protein conserved in bacteria (DUF2252)
MEIPOLNH_00549 1.2e-129 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
MEIPOLNH_00550 1.1e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MEIPOLNH_00551 5.9e-113
MEIPOLNH_00552 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
MEIPOLNH_00553 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MEIPOLNH_00554 1.1e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MEIPOLNH_00555 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MEIPOLNH_00556 7.8e-08 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MEIPOLNH_00558 1.2e-76 yneG S Domain of unknown function (DUF4186)
MEIPOLNH_00559 6.4e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
MEIPOLNH_00560 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
MEIPOLNH_00561 3.4e-202 K WYL domain
MEIPOLNH_00563 0.0 4.2.1.53 S MCRA family
MEIPOLNH_00564 1.6e-46 yhbY J CRS1_YhbY
MEIPOLNH_00565 7.6e-106 S zinc-ribbon domain
MEIPOLNH_00566 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
MEIPOLNH_00567 4.5e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MEIPOLNH_00568 6.5e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MEIPOLNH_00569 1.5e-191 ywqG S Domain of unknown function (DUF1963)
MEIPOLNH_00570 5.3e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEIPOLNH_00571 3.6e-140 recO L Involved in DNA repair and RecF pathway recombination
MEIPOLNH_00572 1.2e-291 I acetylesterase activity
MEIPOLNH_00573 6.1e-236 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MEIPOLNH_00574 1.7e-221 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MEIPOLNH_00575 1.5e-201 2.7.11.1 NU Tfp pilus assembly protein FimV
MEIPOLNH_00577 8.7e-24
MEIPOLNH_00578 5.7e-19
MEIPOLNH_00579 1.4e-149 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
MEIPOLNH_00580 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEIPOLNH_00581 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
MEIPOLNH_00582 9.2e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
MEIPOLNH_00583 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
MEIPOLNH_00584 1.1e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEIPOLNH_00585 3.7e-137 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MEIPOLNH_00586 6e-63
MEIPOLNH_00588 2e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MEIPOLNH_00589 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEIPOLNH_00590 9.7e-90 3.1.21.3 V DivIVA protein
MEIPOLNH_00591 2.1e-42 yggT S YGGT family
MEIPOLNH_00592 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEIPOLNH_00593 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEIPOLNH_00594 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEIPOLNH_00595 7.9e-301 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MEIPOLNH_00596 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
MEIPOLNH_00597 8.9e-159 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MEIPOLNH_00598 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MEIPOLNH_00599 1.3e-84
MEIPOLNH_00600 6.9e-231 O AAA domain (Cdc48 subfamily)
MEIPOLNH_00601 5.4e-164 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MEIPOLNH_00602 4e-60 S Thiamine-binding protein
MEIPOLNH_00603 2.6e-194 K helix_turn _helix lactose operon repressor
MEIPOLNH_00604 5.7e-47 S Protein of unknown function (DUF3052)
MEIPOLNH_00605 1.7e-151 lon T Belongs to the peptidase S16 family
MEIPOLNH_00606 1.1e-284 S Zincin-like metallopeptidase
MEIPOLNH_00607 1.1e-278 uvrD2 3.6.4.12 L DNA helicase
MEIPOLNH_00608 7.2e-238 mphA S Aminoglycoside phosphotransferase
MEIPOLNH_00609 6.1e-32 S Protein of unknown function (DUF3107)
MEIPOLNH_00610 8.7e-167 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
MEIPOLNH_00611 4.4e-115 S Vitamin K epoxide reductase
MEIPOLNH_00612 8.6e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MEIPOLNH_00613 3.9e-153 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MEIPOLNH_00614 3.6e-169 S Patatin-like phospholipase
MEIPOLNH_00615 0.0 V ABC transporter transmembrane region
MEIPOLNH_00616 0.0 V ABC transporter, ATP-binding protein
MEIPOLNH_00617 5.8e-89 K MarR family
MEIPOLNH_00618 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
MEIPOLNH_00619 1e-256 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
MEIPOLNH_00620 3.3e-161
MEIPOLNH_00621 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
MEIPOLNH_00623 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEIPOLNH_00624 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
MEIPOLNH_00625 8.5e-273 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEIPOLNH_00626 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEIPOLNH_00627 1.5e-172 S Endonuclease/Exonuclease/phosphatase family
MEIPOLNH_00630 3.4e-180 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MEIPOLNH_00631 6.5e-254 cdr OP Sulfurtransferase TusA
MEIPOLNH_00632 2.6e-149 moeB 2.7.7.80 H ThiF family
MEIPOLNH_00633 7.7e-132 tmp1 S Domain of unknown function (DUF4391)
MEIPOLNH_00634 2.3e-37 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MEIPOLNH_00635 1.9e-228 aspB E Aminotransferase class-V
MEIPOLNH_00636 6.5e-111 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MEIPOLNH_00637 2.3e-270 S zinc finger
MEIPOLNH_00638 2.6e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEIPOLNH_00639 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEIPOLNH_00640 2.1e-284 O Subtilase family
MEIPOLNH_00641 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
MEIPOLNH_00642 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEIPOLNH_00643 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEIPOLNH_00644 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEIPOLNH_00645 5.5e-35 L Transposase
MEIPOLNH_00646 3.2e-23 relB L RelB antitoxin
MEIPOLNH_00647 4.7e-27 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MEIPOLNH_00648 1.4e-65 gsiA P ATPase activity
MEIPOLNH_00649 1.7e-257 G Major Facilitator Superfamily
MEIPOLNH_00650 9.7e-142 K -acetyltransferase
MEIPOLNH_00651 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
MEIPOLNH_00652 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
MEIPOLNH_00653 4.5e-266 KLT Protein tyrosine kinase
MEIPOLNH_00654 0.0 S Fibronectin type 3 domain
MEIPOLNH_00655 2.6e-231 S ATPase family associated with various cellular activities (AAA)
MEIPOLNH_00656 7.3e-226 S Protein of unknown function DUF58
MEIPOLNH_00657 0.0 E Transglutaminase-like superfamily
MEIPOLNH_00658 3.4e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
MEIPOLNH_00659 1.1e-67 B Belongs to the OprB family
MEIPOLNH_00660 6.5e-96 T Forkhead associated domain
MEIPOLNH_00661 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEIPOLNH_00662 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEIPOLNH_00663 9.6e-102
MEIPOLNH_00664 4.2e-185 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
MEIPOLNH_00665 6.7e-68 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
MEIPOLNH_00666 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEIPOLNH_00668 1.1e-06 S Membrane
MEIPOLNH_00669 9.9e-109
MEIPOLNH_00670 1.2e-252 S UPF0210 protein
MEIPOLNH_00671 4.2e-43 gcvR T Belongs to the UPF0237 family
MEIPOLNH_00672 1.1e-242 EGP Sugar (and other) transporter
MEIPOLNH_00673 2.2e-195 L Integrase core domain
MEIPOLNH_00674 7e-43 Q Psort location Cytoplasmic, score
MEIPOLNH_00675 7.2e-135 tetP J elongation factor G
MEIPOLNH_00676 2.2e-224 tetP J elongation factor G
MEIPOLNH_00677 1.6e-17 S Maff2 family
MEIPOLNH_00678 0.0 U Type IV secretory system Conjugative DNA transfer
MEIPOLNH_00679 1.4e-57 S Protein of unknown function (DUF3801)
MEIPOLNH_00680 9.5e-35 S Psort location Cytoplasmic, score
MEIPOLNH_00681 3.6e-165 L Psort location Cytoplasmic, score
MEIPOLNH_00682 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
MEIPOLNH_00683 4.7e-251 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
MEIPOLNH_00684 8e-144 glpR K DeoR C terminal sensor domain
MEIPOLNH_00685 2.8e-226 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MEIPOLNH_00686 2.5e-219 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
MEIPOLNH_00687 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MEIPOLNH_00688 3.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
MEIPOLNH_00689 2.2e-119 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
MEIPOLNH_00690 2e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MEIPOLNH_00691 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
MEIPOLNH_00692 1.1e-240 S Uncharacterized conserved protein (DUF2183)
MEIPOLNH_00693 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MEIPOLNH_00694 0.0 enhA_2 S L,D-transpeptidase catalytic domain
MEIPOLNH_00695 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MEIPOLNH_00696 4.9e-159 mhpC I Alpha/beta hydrolase family
MEIPOLNH_00697 1.4e-118 F Domain of unknown function (DUF4916)
MEIPOLNH_00698 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
MEIPOLNH_00699 5e-179 S G5
MEIPOLNH_00700 1.4e-161 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
MEIPOLNH_00701 4.4e-111
MEIPOLNH_00702 1e-158 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
MEIPOLNH_00703 3e-228 2.7.7.7 L Transposase and inactivated derivatives
MEIPOLNH_00704 7e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEIPOLNH_00705 9.8e-155 sapF E ATPases associated with a variety of cellular activities
MEIPOLNH_00706 4e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
MEIPOLNH_00707 4.9e-163 EP Binding-protein-dependent transport system inner membrane component
MEIPOLNH_00708 1.4e-170 P Binding-protein-dependent transport system inner membrane component
MEIPOLNH_00709 1.8e-309 E ABC transporter, substrate-binding protein, family 5
MEIPOLNH_00710 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MEIPOLNH_00711 4.8e-276 G Bacterial extracellular solute-binding protein
MEIPOLNH_00712 3.8e-66 G carbohydrate transport
MEIPOLNH_00713 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MEIPOLNH_00714 1.3e-122 G ABC transporter permease
MEIPOLNH_00715 2.9e-190 K Periplasmic binding protein domain
MEIPOLNH_00716 7.7e-21 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MEIPOLNH_00717 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
MEIPOLNH_00719 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEIPOLNH_00720 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MEIPOLNH_00721 2.3e-273 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
MEIPOLNH_00722 1.4e-127 XK27_08050 O prohibitin homologues
MEIPOLNH_00723 1.9e-242 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
MEIPOLNH_00724 2.6e-233 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MEIPOLNH_00725 2.1e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
MEIPOLNH_00726 2.9e-224 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MEIPOLNH_00727 0.0 macB_2 V ATPases associated with a variety of cellular activities
MEIPOLNH_00728 0.0 ctpE P E1-E2 ATPase
MEIPOLNH_00729 3.4e-91 K acetyltransferase
MEIPOLNH_00730 7e-53 racA K MerR, DNA binding
MEIPOLNH_00731 1.1e-197 yghZ C Aldo/keto reductase family
MEIPOLNH_00732 1.9e-100 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
MEIPOLNH_00733 2.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
MEIPOLNH_00734 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
MEIPOLNH_00735 2.7e-123 S Short repeat of unknown function (DUF308)
MEIPOLNH_00736 0.0 pepO 3.4.24.71 O Peptidase family M13
MEIPOLNH_00737 2.2e-104 L Single-strand binding protein family
MEIPOLNH_00738 3.2e-170
MEIPOLNH_00739 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEIPOLNH_00741 1.4e-270 recD2 3.6.4.12 L PIF1-like helicase
MEIPOLNH_00742 8.4e-159 supH S Sucrose-6F-phosphate phosphohydrolase
MEIPOLNH_00743 1.1e-121 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MEIPOLNH_00744 9.5e-81 KT Transcriptional regulatory protein, C terminal
MEIPOLNH_00745 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MEIPOLNH_00746 3.5e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MEIPOLNH_00747 1e-191 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
MEIPOLNH_00748 6.8e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
MEIPOLNH_00749 3e-86 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
MEIPOLNH_00750 1.4e-184 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEIPOLNH_00751 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEIPOLNH_00752 3.9e-36 rpmE J Binds the 23S rRNA
MEIPOLNH_00754 8.4e-193 K helix_turn_helix, arabinose operon control protein
MEIPOLNH_00755 2.6e-163 glcU G Sugar transport protein
MEIPOLNH_00756 4.9e-177 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MEIPOLNH_00757 3.9e-256 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
MEIPOLNH_00758 5.7e-53
MEIPOLNH_00759 3.4e-33
MEIPOLNH_00760 4.8e-129 S Metallo-beta-lactamase domain protein
MEIPOLNH_00761 3.1e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
MEIPOLNH_00762 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
MEIPOLNH_00763 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
MEIPOLNH_00764 5.5e-164 EG EamA-like transporter family
MEIPOLNH_00766 4.5e-125 V FtsX-like permease family
MEIPOLNH_00767 9.1e-148 S Sulfite exporter TauE/SafE
MEIPOLNH_00769 1.9e-26 L Transposase
MEIPOLNH_00770 3.4e-216 MA20_36090 S Psort location Cytoplasmic, score 8.87
MEIPOLNH_00771 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
MEIPOLNH_00772 3.3e-50 EGP Major facilitator superfamily
MEIPOLNH_00773 1.2e-11 EGP Major facilitator superfamily
MEIPOLNH_00774 5.2e-10 K Winged helix DNA-binding domain
MEIPOLNH_00775 3.7e-179 glkA 2.7.1.2 G ROK family
MEIPOLNH_00776 4.1e-300 S ATPases associated with a variety of cellular activities
MEIPOLNH_00777 1.8e-54 EGP Major facilitator Superfamily
MEIPOLNH_00778 2.1e-157 I alpha/beta hydrolase fold
MEIPOLNH_00779 1.4e-110 S Pyridoxamine 5'-phosphate oxidase
MEIPOLNH_00781 8.2e-63 S DUF218 domain
MEIPOLNH_00783 8.4e-52 S Protein of unknown function (DUF979)
MEIPOLNH_00784 4.4e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MEIPOLNH_00786 2e-126
MEIPOLNH_00787 4.7e-48 M domain, Protein
MEIPOLNH_00788 4e-19 M domain, Protein
MEIPOLNH_00789 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
MEIPOLNH_00790 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
MEIPOLNH_00791 3.9e-170 tesB I Thioesterase-like superfamily
MEIPOLNH_00792 2.2e-75 S Protein of unknown function (DUF3180)
MEIPOLNH_00793 3.3e-291 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MEIPOLNH_00794 2.4e-161 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MEIPOLNH_00795 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
MEIPOLNH_00796 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEIPOLNH_00797 2.1e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MEIPOLNH_00798 1.3e-212 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEIPOLNH_00799 8.5e-260 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
MEIPOLNH_00800 1.2e-307
MEIPOLNH_00801 1.4e-167 natA V ATPases associated with a variety of cellular activities
MEIPOLNH_00802 1.3e-232 epsG M Glycosyl transferase family 21
MEIPOLNH_00803 5.7e-273 S AI-2E family transporter
MEIPOLNH_00804 4.7e-176 3.4.14.13 M Glycosyltransferase like family 2
MEIPOLNH_00805 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
MEIPOLNH_00808 2.6e-68 S Domain of unknown function (DUF4190)
MEIPOLNH_00809 6.9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MEIPOLNH_00810 4.8e-176 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEIPOLNH_00812 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
MEIPOLNH_00813 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MEIPOLNH_00814 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
MEIPOLNH_00815 8.9e-184 lacR K Transcriptional regulator, LacI family
MEIPOLNH_00816 5.2e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MEIPOLNH_00817 3.9e-119 K Transcriptional regulatory protein, C terminal
MEIPOLNH_00818 1.4e-100
MEIPOLNH_00819 1.5e-178 V N-Acetylmuramoyl-L-alanine amidase
MEIPOLNH_00820 7.4e-109 ytrE V ABC transporter
MEIPOLNH_00821 6.6e-172
MEIPOLNH_00823 4.7e-220 vex3 V ABC transporter permease
MEIPOLNH_00824 1.2e-211 vex1 V Efflux ABC transporter, permease protein
MEIPOLNH_00825 8.3e-111 vex2 V ABC transporter, ATP-binding protein
MEIPOLNH_00826 2.4e-37 azlD E Branched-chain amino acid transport protein (AzlD)
MEIPOLNH_00827 1.1e-195 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
MEIPOLNH_00828 5.2e-95 ptpA 3.1.3.48 T low molecular weight
MEIPOLNH_00829 1.7e-127 folA 1.5.1.3 H dihydrofolate reductase
MEIPOLNH_00830 2.1e-173 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEIPOLNH_00831 1e-72 attW O OsmC-like protein
MEIPOLNH_00832 4.6e-191 T Universal stress protein family
MEIPOLNH_00833 2.4e-107 M NlpC/P60 family
MEIPOLNH_00834 8.2e-177 usp 3.5.1.28 CBM50 S CHAP domain
MEIPOLNH_00835 4.2e-214 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEIPOLNH_00836 2.6e-39
MEIPOLNH_00837 1.6e-217 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEIPOLNH_00838 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
MEIPOLNH_00839 2.3e-09 EGP Major facilitator Superfamily
MEIPOLNH_00840 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEIPOLNH_00841 9.5e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MEIPOLNH_00842 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MEIPOLNH_00844 4.3e-217 araJ EGP Major facilitator Superfamily
MEIPOLNH_00845 0.0 S Domain of unknown function (DUF4037)
MEIPOLNH_00846 2.8e-111 S Protein of unknown function (DUF4125)
MEIPOLNH_00847 5.3e-120
MEIPOLNH_00848 8.9e-288 pspC KT PspC domain
MEIPOLNH_00849 1.1e-264 tcsS3 KT PspC domain
MEIPOLNH_00850 4.6e-125 degU K helix_turn_helix, Lux Regulon
MEIPOLNH_00851 4.5e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEIPOLNH_00853 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MEIPOLNH_00854 1.2e-185 opcA G Glucose-6-phosphate dehydrogenase subunit
MEIPOLNH_00855 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEIPOLNH_00856 1.7e-93
MEIPOLNH_00858 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
MEIPOLNH_00860 2.3e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEIPOLNH_00861 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
MEIPOLNH_00862 3.2e-214 I Diacylglycerol kinase catalytic domain
MEIPOLNH_00863 1.3e-151 arbG K CAT RNA binding domain
MEIPOLNH_00864 0.0 crr G pts system, glucose-specific IIABC component
MEIPOLNH_00865 6.8e-43 M Spy0128-like isopeptide containing domain
MEIPOLNH_00866 3.2e-44 M Spy0128-like isopeptide containing domain
MEIPOLNH_00868 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MEIPOLNH_00869 7.5e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MEIPOLNH_00870 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
MEIPOLNH_00871 1.2e-202 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEIPOLNH_00872 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEIPOLNH_00874 8e-106
MEIPOLNH_00875 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEIPOLNH_00876 8.5e-232 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
MEIPOLNH_00877 2.1e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEIPOLNH_00878 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEIPOLNH_00879 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEIPOLNH_00880 2.8e-188 nusA K Participates in both transcription termination and antitermination
MEIPOLNH_00881 8.7e-160
MEIPOLNH_00882 6e-72 L Transposase and inactivated derivatives
MEIPOLNH_00883 1.7e-33
MEIPOLNH_00885 1.3e-153 E Transglutaminase/protease-like homologues
MEIPOLNH_00886 0.0 gcs2 S A circularly permuted ATPgrasp
MEIPOLNH_00887 8.3e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEIPOLNH_00888 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
MEIPOLNH_00889 2.8e-64 rplQ J Ribosomal protein L17
MEIPOLNH_00890 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEIPOLNH_00891 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEIPOLNH_00892 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEIPOLNH_00893 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MEIPOLNH_00894 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEIPOLNH_00895 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEIPOLNH_00896 8.9e-248 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEIPOLNH_00897 2.7e-63 rplO J binds to the 23S rRNA
MEIPOLNH_00898 1e-24 rpmD J Ribosomal protein L30p/L7e
MEIPOLNH_00899 1.9e-98 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEIPOLNH_00900 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEIPOLNH_00901 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEIPOLNH_00902 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEIPOLNH_00903 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEIPOLNH_00904 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEIPOLNH_00905 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEIPOLNH_00906 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEIPOLNH_00907 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEIPOLNH_00908 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
MEIPOLNH_00909 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEIPOLNH_00910 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEIPOLNH_00911 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEIPOLNH_00912 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEIPOLNH_00913 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEIPOLNH_00914 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEIPOLNH_00915 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
MEIPOLNH_00916 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEIPOLNH_00917 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
MEIPOLNH_00918 3e-14 ywiC S YwiC-like protein
MEIPOLNH_00919 1.9e-111 ywiC S YwiC-like protein
MEIPOLNH_00920 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MEIPOLNH_00921 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MEIPOLNH_00922 3.1e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MEIPOLNH_00923 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MEIPOLNH_00924 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
MEIPOLNH_00925 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEIPOLNH_00926 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MEIPOLNH_00927 1.8e-120
MEIPOLNH_00928 1.1e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
MEIPOLNH_00929 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
MEIPOLNH_00931 6e-241 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEIPOLNH_00932 1.4e-225 dapC E Aminotransferase class I and II
MEIPOLNH_00933 9e-61 fdxA C 4Fe-4S binding domain
MEIPOLNH_00934 3.3e-217 murB 1.3.1.98 M Cell wall formation
MEIPOLNH_00935 1.9e-25 rpmG J Ribosomal protein L33
MEIPOLNH_00939 1.2e-51 moxR S ATPase family associated with various cellular activities (AAA)
MEIPOLNH_00940 2.1e-132 bla1 3.5.2.6 V Beta-lactamase enzyme family
MEIPOLNH_00941 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEIPOLNH_00942 7.1e-123
MEIPOLNH_00943 2e-93 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
MEIPOLNH_00944 1.8e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
MEIPOLNH_00945 3.2e-38 fmdB S Putative regulatory protein
MEIPOLNH_00946 5.6e-110 flgA NO SAF
MEIPOLNH_00947 9.6e-42
MEIPOLNH_00948 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
MEIPOLNH_00949 1.8e-239 T Forkhead associated domain
MEIPOLNH_00951 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEIPOLNH_00952 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEIPOLNH_00953 2.3e-179 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
MEIPOLNH_00954 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
MEIPOLNH_00956 8.8e-222 pbuO S Permease family
MEIPOLNH_00957 5.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MEIPOLNH_00958 6.5e-148 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MEIPOLNH_00959 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEIPOLNH_00960 1.1e-179 pstA P Phosphate transport system permease
MEIPOLNH_00961 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
MEIPOLNH_00962 1.3e-170 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
MEIPOLNH_00963 3.7e-128 KT Transcriptional regulatory protein, C terminal
MEIPOLNH_00964 6.7e-243 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MEIPOLNH_00965 1.9e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEIPOLNH_00966 4.6e-238 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MEIPOLNH_00967 7.7e-106 K helix_turn_helix, Arsenical Resistance Operon Repressor
MEIPOLNH_00968 1.4e-240 EGP Major facilitator Superfamily
MEIPOLNH_00969 3.7e-218 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MEIPOLNH_00970 3.5e-167 L Excalibur calcium-binding domain
MEIPOLNH_00971 3.2e-269 pepC 3.4.22.40 E Peptidase C1-like family
MEIPOLNH_00972 3.3e-46 D nuclear chromosome segregation
MEIPOLNH_00973 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MEIPOLNH_00974 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MEIPOLNH_00975 1.8e-187 yfiH Q Multi-copper polyphenol oxidoreductase laccase
MEIPOLNH_00976 0.0 yegQ O Peptidase family U32 C-terminal domain
MEIPOLNH_00977 4e-93 L Transposase and inactivated derivatives IS30 family
MEIPOLNH_00978 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
MEIPOLNH_00979 2.2e-41 nrdH O Glutaredoxin
MEIPOLNH_00980 1.2e-97 nrdI F Probably involved in ribonucleotide reductase function
MEIPOLNH_00981 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEIPOLNH_00982 1.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEIPOLNH_00983 1.6e-74 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MEIPOLNH_00984 0.0 S Predicted membrane protein (DUF2207)
MEIPOLNH_00985 1e-91 lemA S LemA family
MEIPOLNH_00986 3.6e-115 xylR K purine nucleotide biosynthetic process
MEIPOLNH_00987 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MEIPOLNH_00988 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEIPOLNH_00989 8.9e-119
MEIPOLNH_00990 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
MEIPOLNH_00992 3.9e-159 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MEIPOLNH_00993 1.7e-99 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEIPOLNH_00994 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
MEIPOLNH_00995 7.2e-308 pccB I Carboxyl transferase domain
MEIPOLNH_00996 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MEIPOLNH_00997 4.2e-93 bioY S BioY family
MEIPOLNH_00998 4.4e-152 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MEIPOLNH_00999 0.0
MEIPOLNH_01000 5.9e-146 QT PucR C-terminal helix-turn-helix domain
MEIPOLNH_01001 1.2e-129 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MEIPOLNH_01002 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MEIPOLNH_01003 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEIPOLNH_01004 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEIPOLNH_01005 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEIPOLNH_01006 1.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEIPOLNH_01007 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEIPOLNH_01008 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEIPOLNH_01010 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
MEIPOLNH_01011 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MEIPOLNH_01013 4.6e-35
MEIPOLNH_01014 0.0 K RNA polymerase II activating transcription factor binding
MEIPOLNH_01015 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MEIPOLNH_01016 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MEIPOLNH_01018 1.3e-102 mntP P Probably functions as a manganese efflux pump
MEIPOLNH_01019 1.4e-125
MEIPOLNH_01020 2e-135 KT Transcriptional regulatory protein, C terminal
MEIPOLNH_01021 5.6e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEIPOLNH_01022 4.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
MEIPOLNH_01023 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEIPOLNH_01024 0.0 S domain protein
MEIPOLNH_01025 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
MEIPOLNH_01026 3.1e-90 lrp_3 K helix_turn_helix ASNC type
MEIPOLNH_01027 8.8e-234 E Aminotransferase class I and II
MEIPOLNH_01028 1.7e-309 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MEIPOLNH_01029 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
MEIPOLNH_01031 2.5e-52 S Protein of unknown function (DUF2469)
MEIPOLNH_01032 1.1e-197 2.3.1.57 J Acetyltransferase (GNAT) domain
MEIPOLNH_01033 1.9e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEIPOLNH_01034 6.4e-290 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEIPOLNH_01035 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEIPOLNH_01036 1.9e-11 V ABC transporter
MEIPOLNH_01037 4.4e-59 V ABC transporter
MEIPOLNH_01038 1.5e-56 V ABC transporter
MEIPOLNH_01039 1.7e-157 spoU 2.1.1.185 J RNA methyltransferase TrmH family
MEIPOLNH_01040 5e-128 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEIPOLNH_01041 4.9e-214 rmuC S RmuC family
MEIPOLNH_01042 9.6e-43 csoR S Metal-sensitive transcriptional repressor
MEIPOLNH_01043 0.0 pacS 3.6.3.54 P E1-E2 ATPase
MEIPOLNH_01044 0.0 ubiB S ABC1 family
MEIPOLNH_01045 2.8e-16 S granule-associated protein
MEIPOLNH_01046 2.2e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MEIPOLNH_01047 1.7e-282 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
MEIPOLNH_01048 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MEIPOLNH_01049 5.9e-250 dinF V MatE
MEIPOLNH_01050 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
MEIPOLNH_01051 1e-54 glnB K Nitrogen regulatory protein P-II
MEIPOLNH_01052 3.4e-220 amt U Ammonium Transporter Family
MEIPOLNH_01053 2.6e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEIPOLNH_01055 2.7e-116 icaR K Bacterial regulatory proteins, tetR family
MEIPOLNH_01056 4.7e-196 XK27_01805 M Glycosyltransferase like family 2
MEIPOLNH_01057 0.0 S Glycosyl hydrolases related to GH101 family, GH129
MEIPOLNH_01058 3.2e-305 pepD E Peptidase family C69
MEIPOLNH_01060 5e-92 XK26_04485 P Cobalt transport protein
MEIPOLNH_01061 1.6e-84
MEIPOLNH_01062 0.0 V ABC transporter transmembrane region
MEIPOLNH_01063 1.8e-301 V ABC transporter, ATP-binding protein
MEIPOLNH_01064 1.3e-81 K Winged helix DNA-binding domain
MEIPOLNH_01065 3e-73 E IrrE N-terminal-like domain
MEIPOLNH_01067 5.2e-09 S Sucrose-6F-phosphate phosphohydrolase
MEIPOLNH_01068 1.1e-158 S Sucrose-6F-phosphate phosphohydrolase
MEIPOLNH_01069 6.6e-240 S Putative ABC-transporter type IV
MEIPOLNH_01070 2e-80
MEIPOLNH_01071 1.5e-33 Q phosphatase activity
MEIPOLNH_01072 3e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
MEIPOLNH_01073 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MEIPOLNH_01074 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MEIPOLNH_01075 2.1e-249 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEIPOLNH_01076 4.6e-67 S haloacid dehalogenase-like hydrolase
MEIPOLNH_01077 9.6e-11 S haloacid dehalogenase-like hydrolase
MEIPOLNH_01078 3.6e-131 yydK K UTRA
MEIPOLNH_01079 1.3e-70 S FMN_bind
MEIPOLNH_01080 5.7e-149 macB V ABC transporter, ATP-binding protein
MEIPOLNH_01081 8.3e-203 Z012_06715 V FtsX-like permease family
MEIPOLNH_01082 3.7e-222 macB_2 V ABC transporter permease
MEIPOLNH_01083 3.5e-233 S Predicted membrane protein (DUF2318)
MEIPOLNH_01084 6.4e-109 tpd P Fe2+ transport protein
MEIPOLNH_01085 1.9e-306 efeU_1 P Iron permease FTR1 family
MEIPOLNH_01086 2e-18 G MFS/sugar transport protein
MEIPOLNH_01087 3.8e-201 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEIPOLNH_01088 8.3e-126 S Fic/DOC family
MEIPOLNH_01089 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEIPOLNH_01090 5e-38 ptsH G PTS HPr component phosphorylation site
MEIPOLNH_01091 4.6e-197 K helix_turn _helix lactose operon repressor
MEIPOLNH_01092 8.6e-210 holB 2.7.7.7 L DNA polymerase III
MEIPOLNH_01093 2.3e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEIPOLNH_01094 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEIPOLNH_01095 8.8e-188 3.6.1.27 I PAP2 superfamily
MEIPOLNH_01096 0.0 vpr M PA domain
MEIPOLNH_01097 4.7e-123 yplQ S Haemolysin-III related
MEIPOLNH_01098 9.3e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
MEIPOLNH_01099 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MEIPOLNH_01100 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MEIPOLNH_01101 1e-278 S Calcineurin-like phosphoesterase
MEIPOLNH_01102 6.7e-15 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MEIPOLNH_01103 1.5e-280 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MEIPOLNH_01104 1.7e-116
MEIPOLNH_01105 1.7e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEIPOLNH_01107 1.8e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
MEIPOLNH_01108 5.3e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MEIPOLNH_01109 1.9e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEIPOLNH_01110 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
MEIPOLNH_01111 2.4e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
MEIPOLNH_01112 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
MEIPOLNH_01113 4.8e-55 U TadE-like protein
MEIPOLNH_01114 3.2e-41 S Protein of unknown function (DUF4244)
MEIPOLNH_01115 9.5e-79 gspF NU Type II secretion system (T2SS), protein F
MEIPOLNH_01116 2.8e-120 U Type ii secretion system
MEIPOLNH_01117 3.4e-191 cpaF U Type II IV secretion system protein
MEIPOLNH_01118 1.3e-151 cpaE D bacterial-type flagellum organization
MEIPOLNH_01120 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MEIPOLNH_01121 6.3e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
MEIPOLNH_01122 5e-91
MEIPOLNH_01123 2.1e-42 cbiM P PDGLE domain
MEIPOLNH_01124 2.2e-57 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MEIPOLNH_01125 9.4e-208 S Glycosyltransferase, group 2 family protein
MEIPOLNH_01126 7.2e-275
MEIPOLNH_01127 8.7e-27 thiS 2.8.1.10 H ThiS family
MEIPOLNH_01128 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MEIPOLNH_01129 0.0 S Psort location Cytoplasmic, score 8.87
MEIPOLNH_01130 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
MEIPOLNH_01131 2.6e-245 V ABC transporter permease
MEIPOLNH_01132 4.9e-182 V ABC transporter
MEIPOLNH_01133 4.6e-137 T HD domain
MEIPOLNH_01134 8e-165 S Glutamine amidotransferase domain
MEIPOLNH_01136 0.0 kup P Transport of potassium into the cell
MEIPOLNH_01137 5.9e-185 tatD L TatD related DNase
MEIPOLNH_01138 2.1e-250 xylR 5.3.1.12 G MFS/sugar transport protein
MEIPOLNH_01140 3.4e-86 K Transcriptional regulator
MEIPOLNH_01141 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEIPOLNH_01142 1.6e-130
MEIPOLNH_01143 8.6e-59
MEIPOLNH_01144 4.6e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEIPOLNH_01145 2.7e-126 dedA S SNARE associated Golgi protein
MEIPOLNH_01147 1.8e-133 S HAD hydrolase, family IA, variant 3
MEIPOLNH_01148 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
MEIPOLNH_01149 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
MEIPOLNH_01150 5.2e-87 hspR K transcriptional regulator, MerR family
MEIPOLNH_01151 7.1e-173 dnaJ1 O DnaJ molecular chaperone homology domain
MEIPOLNH_01152 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEIPOLNH_01153 0.0 dnaK O Heat shock 70 kDa protein
MEIPOLNH_01154 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
MEIPOLNH_01155 2.9e-190 K Psort location Cytoplasmic, score
MEIPOLNH_01158 1.8e-138 G Phosphoglycerate mutase family
MEIPOLNH_01159 3e-69 S Protein of unknown function (DUF4235)
MEIPOLNH_01160 2.8e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
MEIPOLNH_01161 1.1e-45
MEIPOLNH_01162 4e-144 cobB2 K Sir2 family
MEIPOLNH_01163 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MEIPOLNH_01164 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEIPOLNH_01165 1.2e-145 ypfH S Phospholipase/Carboxylesterase
MEIPOLNH_01166 0.0 yjcE P Sodium/hydrogen exchanger family
MEIPOLNH_01167 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
MEIPOLNH_01168 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
MEIPOLNH_01169 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
MEIPOLNH_01171 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEIPOLNH_01172 2e-269 KLT Domain of unknown function (DUF4032)
MEIPOLNH_01173 1.2e-144
MEIPOLNH_01174 1.3e-179 3.4.22.70 M Sortase family
MEIPOLNH_01175 1.9e-244 M LPXTG-motif cell wall anchor domain protein
MEIPOLNH_01176 0.0 S LPXTG-motif cell wall anchor domain protein
MEIPOLNH_01177 9.5e-103 L Helix-turn-helix domain
MEIPOLNH_01178 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
MEIPOLNH_01179 3.4e-174 K Psort location Cytoplasmic, score
MEIPOLNH_01180 0.0 KLT Protein tyrosine kinase
MEIPOLNH_01181 3.3e-151 O Thioredoxin
MEIPOLNH_01183 1.2e-211 S G5
MEIPOLNH_01184 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEIPOLNH_01185 6e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEIPOLNH_01186 6.7e-113 S LytR cell envelope-related transcriptional attenuator
MEIPOLNH_01187 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
MEIPOLNH_01188 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
MEIPOLNH_01189 0.0 M Conserved repeat domain
MEIPOLNH_01190 0.0 murJ KLT MviN-like protein
MEIPOLNH_01191 2.9e-202 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEIPOLNH_01192 2.3e-243 parB K Belongs to the ParB family
MEIPOLNH_01193 1.2e-177 parA D CobQ CobB MinD ParA nucleotide binding domain protein
MEIPOLNH_01194 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MEIPOLNH_01195 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
MEIPOLNH_01196 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
MEIPOLNH_01197 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MEIPOLNH_01198 1.7e-298 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEIPOLNH_01199 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEIPOLNH_01200 5.2e-240 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEIPOLNH_01201 9e-85 S Protein of unknown function (DUF721)
MEIPOLNH_01202 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEIPOLNH_01203 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEIPOLNH_01204 6.7e-72 S Transmembrane domain of unknown function (DUF3566)
MEIPOLNH_01205 6.5e-14 abfA1 3.2.1.55 GH51 G arabinose metabolic process
MEIPOLNH_01206 1.2e-06 S Parallel beta-helix repeats
MEIPOLNH_01207 4.6e-187 G Glycosyl hydrolases family 43
MEIPOLNH_01208 5.5e-188 K Periplasmic binding protein domain
MEIPOLNH_01209 1.2e-227 I Serine aminopeptidase, S33
MEIPOLNH_01210 8.3e-09 K helix_turn _helix lactose operon repressor
MEIPOLNH_01212 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MEIPOLNH_01213 2.5e-124 gntR K FCD
MEIPOLNH_01214 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEIPOLNH_01215 0.0 3.2.1.55 GH51 G arabinose metabolic process
MEIPOLNH_01218 0.0 G Glycosyl hydrolase family 20, domain 2
MEIPOLNH_01219 6.3e-188 K helix_turn _helix lactose operon repressor
MEIPOLNH_01220 8.6e-78 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEIPOLNH_01221 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
MEIPOLNH_01222 3.6e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MEIPOLNH_01223 3.3e-135 S Protein of unknown function DUF45
MEIPOLNH_01224 3.3e-83 dps P Belongs to the Dps family
MEIPOLNH_01225 4.1e-187 yddG EG EamA-like transporter family
MEIPOLNH_01226 1.2e-241 ytfL P Transporter associated domain
MEIPOLNH_01227 2e-92 K helix_turn _helix lactose operon repressor
MEIPOLNH_01228 6.4e-117 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MEIPOLNH_01229 1.4e-106 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
MEIPOLNH_01230 0.0 trxB1 1.8.1.9 C Thioredoxin domain
MEIPOLNH_01231 6.1e-307 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MEIPOLNH_01232 7.3e-239 yhjX EGP Major facilitator Superfamily
MEIPOLNH_01233 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MEIPOLNH_01234 0.0 yjjP S Threonine/Serine exporter, ThrE
MEIPOLNH_01235 7e-155 S Amidohydrolase family
MEIPOLNH_01236 5.2e-17 S Amidohydrolase family
MEIPOLNH_01237 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MEIPOLNH_01238 1.9e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEIPOLNH_01239 1e-47 S Protein of unknown function (DUF3073)
MEIPOLNH_01240 1.6e-88 K LytTr DNA-binding domain
MEIPOLNH_01241 2.7e-111 T protein histidine kinase activity
MEIPOLNH_01242 2.3e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEIPOLNH_01243 3.3e-23 I transferase activity, transferring acyl groups other than amino-acyl groups
MEIPOLNH_01244 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
MEIPOLNH_01245 6.2e-167 rfbJ M Glycosyl transferase family 2
MEIPOLNH_01246 2.7e-138 tnp7109-2 L Transposase, Mutator family
MEIPOLNH_01247 2.8e-72 L Transposase
MEIPOLNH_01248 1.3e-207 S Acyltransferase family
MEIPOLNH_01249 6.5e-298
MEIPOLNH_01250 0.0 wbbM M Glycosyl transferase family 8
MEIPOLNH_01251 2.6e-174 ppm1 GT2 M Glycosyl transferase, family 2
MEIPOLNH_01252 0.0 M Belongs to the glycosyl hydrolase 43 family
MEIPOLNH_01253 9.8e-127 L IstB-like ATP binding protein
MEIPOLNH_01254 1.7e-253 L Transposase
MEIPOLNH_01255 1.6e-142 M Putative cell wall binding repeat 2
MEIPOLNH_01256 2.1e-120 L Protein of unknown function (DUF1524)
MEIPOLNH_01257 0.0 2.1.1.72, 3.1.4.46, 3.2.1.1 GH13 M hydrolase, family 25
MEIPOLNH_01258 1.8e-240 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
MEIPOLNH_01259 2.5e-139 rgpC U Transport permease protein
MEIPOLNH_01260 0.0 wbbM M Glycosyl transferase family 8
MEIPOLNH_01261 8.4e-216 1.1.1.22 M UDP binding domain
MEIPOLNH_01262 4.4e-15 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MEIPOLNH_01263 7.9e-153 K Transposase IS116 IS110 IS902
MEIPOLNH_01264 7.3e-119 tnp7109-21 L Integrase core domain
MEIPOLNH_01265 2.6e-43 L Transposase
MEIPOLNH_01266 3.3e-09
MEIPOLNH_01268 9.5e-45 L Transposase DDE domain
MEIPOLNH_01269 5.2e-155 bglA 3.2.1.21 G Glycosyl hydrolase family 1
MEIPOLNH_01270 2e-203 L Transposase, Mutator family
MEIPOLNH_01271 1.8e-228 glf 5.4.99.9 M UDP-galactopyranose mutase
MEIPOLNH_01272 6.1e-45 3.6.1.13 L NUDIX domain
MEIPOLNH_01273 1.4e-102
MEIPOLNH_01274 5.6e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEIPOLNH_01275 1e-216 G Transmembrane secretion effector
MEIPOLNH_01276 2.7e-118 K Bacterial regulatory proteins, tetR family
MEIPOLNH_01277 4.5e-12
MEIPOLNH_01278 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
MEIPOLNH_01279 4.3e-42 tnp7109-21 L Integrase core domain
MEIPOLNH_01280 3.8e-09 L IstB-like ATP binding protein
MEIPOLNH_01281 7.4e-45 L Transposase
MEIPOLNH_01282 1.1e-17 V ATPases associated with a variety of cellular activities
MEIPOLNH_01283 2e-73 I Sterol carrier protein
MEIPOLNH_01284 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MEIPOLNH_01286 3.4e-35
MEIPOLNH_01287 6.4e-145 gluP 3.4.21.105 S Rhomboid family
MEIPOLNH_01288 3.8e-123 L HTH-like domain
MEIPOLNH_01289 1.6e-257 L ribosomal rna small subunit methyltransferase
MEIPOLNH_01290 6.9e-67 crgA D Involved in cell division
MEIPOLNH_01291 7.9e-143 S Bacterial protein of unknown function (DUF881)
MEIPOLNH_01292 4.4e-233 srtA 3.4.22.70 M Sortase family
MEIPOLNH_01293 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
MEIPOLNH_01294 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
MEIPOLNH_01295 2e-183 T Protein tyrosine kinase
MEIPOLNH_01296 2.4e-262 pbpA M penicillin-binding protein
MEIPOLNH_01297 2.3e-265 rodA D Belongs to the SEDS family
MEIPOLNH_01298 5.3e-258 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
MEIPOLNH_01299 3.9e-93 fhaB T Inner membrane component of T3SS, cytoplasmic domain
MEIPOLNH_01300 1e-130 fhaA T Protein of unknown function (DUF2662)
MEIPOLNH_01301 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
MEIPOLNH_01302 0.0 pip S YhgE Pip domain protein
MEIPOLNH_01303 1.9e-269 pip S YhgE Pip domain protein
MEIPOLNH_01304 6.7e-206 pldB 3.1.1.5 I Serine aminopeptidase, S33
MEIPOLNH_01305 3.9e-168 yicL EG EamA-like transporter family
MEIPOLNH_01306 2e-103
MEIPOLNH_01308 1.7e-195 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEIPOLNH_01309 0.0 KL Domain of unknown function (DUF3427)
MEIPOLNH_01310 1.7e-90 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MEIPOLNH_01311 8.8e-39 D DivIVA domain protein
MEIPOLNH_01312 9.3e-53 ybjQ S Putative heavy-metal-binding
MEIPOLNH_01313 4.5e-157 I Serine aminopeptidase, S33
MEIPOLNH_01314 4.1e-86 yjcF Q Acetyltransferase (GNAT) domain
MEIPOLNH_01316 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEIPOLNH_01317 1.4e-241 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
MEIPOLNH_01318 0.0 cadA P E1-E2 ATPase
MEIPOLNH_01319 5e-273 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
MEIPOLNH_01320 1.6e-171 htpX O Belongs to the peptidase M48B family
MEIPOLNH_01322 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MEIPOLNH_01323 1.9e-42 S Bacterial mobilisation protein (MobC)
MEIPOLNH_01324 2.3e-127 S Domain of unknown function (DUF4417)
MEIPOLNH_01326 1.9e-61
MEIPOLNH_01327 6.8e-65
MEIPOLNH_01328 3.9e-50 E IrrE N-terminal-like domain
MEIPOLNH_01329 2e-12 E IrrE N-terminal-like domain
MEIPOLNH_01330 4.9e-57 K Cro/C1-type HTH DNA-binding domain
MEIPOLNH_01331 3.1e-245 3.5.1.104 G Polysaccharide deacetylase
MEIPOLNH_01332 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MEIPOLNH_01333 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEIPOLNH_01334 3.7e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEIPOLNH_01335 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEIPOLNH_01336 8.4e-193 K helix_turn _helix lactose operon repressor
MEIPOLNH_01337 4.8e-78 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
MEIPOLNH_01338 7.2e-295 scrT G Transporter major facilitator family protein
MEIPOLNH_01339 3.6e-252 yhjE EGP Sugar (and other) transporter
MEIPOLNH_01340 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MEIPOLNH_01341 1.2e-202 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MEIPOLNH_01342 1.2e-180 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
MEIPOLNH_01343 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MEIPOLNH_01344 9.6e-275 aroP E aromatic amino acid transport protein AroP K03293
MEIPOLNH_01345 2.4e-101 K Transcriptional regulator C-terminal region
MEIPOLNH_01346 2.6e-129 V ABC transporter
MEIPOLNH_01347 0.0 V FtsX-like permease family
MEIPOLNH_01348 1.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEIPOLNH_01349 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEIPOLNH_01350 1.3e-35 E ABC transporter
MEIPOLNH_01351 3.2e-95 bcp 1.11.1.15 O Redoxin
MEIPOLNH_01352 3.7e-158 S Virulence factor BrkB
MEIPOLNH_01353 2.1e-41 XAC3035 O Glutaredoxin
MEIPOLNH_01354 2.7e-13
MEIPOLNH_01355 2.2e-127 O Subtilase family
MEIPOLNH_01356 5.1e-68
MEIPOLNH_01357 8.3e-56
MEIPOLNH_01359 1.3e-16 M Belongs to the glycosyl hydrolase 30 family
MEIPOLNH_01360 6.5e-96 M Belongs to the glycosyl hydrolase 30 family
MEIPOLNH_01361 9.7e-191 1.1.1.65 C Aldo/keto reductase family
MEIPOLNH_01362 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
MEIPOLNH_01363 0.0 lmrA1 V ABC transporter, ATP-binding protein
MEIPOLNH_01364 0.0 lmrA2 V ABC transporter transmembrane region
MEIPOLNH_01365 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
MEIPOLNH_01366 1.3e-107 S Phosphatidylethanolamine-binding protein
MEIPOLNH_01367 0.0 pepD E Peptidase family C69
MEIPOLNH_01368 1.4e-286 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
MEIPOLNH_01369 1.3e-62 S Macrophage migration inhibitory factor (MIF)
MEIPOLNH_01370 4.4e-97 S GtrA-like protein
MEIPOLNH_01371 5.2e-262 EGP Major facilitator Superfamily
MEIPOLNH_01372 8.1e-125 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
MEIPOLNH_01373 7.1e-143
MEIPOLNH_01374 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
MEIPOLNH_01375 1.7e-201 P NMT1/THI5 like
MEIPOLNH_01376 3.1e-124 S HAD hydrolase, family IA, variant 3
MEIPOLNH_01378 6.3e-298 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEIPOLNH_01379 3.1e-95 S Domain of unknown function (DUF4143)
MEIPOLNH_01380 1.4e-63 S Domain of unknown function (DUF4143)
MEIPOLNH_01383 1.3e-251 S Calcineurin-like phosphoesterase
MEIPOLNH_01384 2.8e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
MEIPOLNH_01385 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEIPOLNH_01386 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEIPOLNH_01387 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
MEIPOLNH_01389 5.1e-180 S CAAX protease self-immunity
MEIPOLNH_01390 4e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
MEIPOLNH_01391 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEIPOLNH_01392 4.8e-225 G Transmembrane secretion effector
MEIPOLNH_01393 7.3e-132 K Bacterial regulatory proteins, tetR family
MEIPOLNH_01394 1.5e-124
MEIPOLNH_01395 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEIPOLNH_01396 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEIPOLNH_01397 9.8e-167 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
MEIPOLNH_01398 5.4e-187
MEIPOLNH_01399 7.9e-180
MEIPOLNH_01400 1.3e-163 trxA2 O Tetratricopeptide repeat
MEIPOLNH_01401 2.8e-119 cyaA 4.6.1.1 S CYTH
MEIPOLNH_01403 4.1e-184 K Bacterial regulatory proteins, lacI family
MEIPOLNH_01404 3.9e-16 4.2.1.68 M carboxylic acid catabolic process
MEIPOLNH_01405 9.5e-41 4.2.1.68 M Enolase C-terminal domain-like
MEIPOLNH_01406 3.4e-163 IQ KR domain
MEIPOLNH_01408 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MEIPOLNH_01409 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
MEIPOLNH_01410 2e-18 psp1 3.5.99.10 J Endoribonuclease L-PSP
MEIPOLNH_01411 2.2e-179 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MEIPOLNH_01412 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MEIPOLNH_01413 2.8e-304 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEIPOLNH_01414 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MEIPOLNH_01415 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
MEIPOLNH_01416 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
MEIPOLNH_01417 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEIPOLNH_01418 2e-277 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
MEIPOLNH_01419 2.1e-64
MEIPOLNH_01420 8e-58
MEIPOLNH_01421 4.9e-165 V ATPases associated with a variety of cellular activities
MEIPOLNH_01422 3.3e-256 V Efflux ABC transporter, permease protein
MEIPOLNH_01423 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
MEIPOLNH_01424 3.2e-239 dapE 3.5.1.18 E Peptidase dimerisation domain
MEIPOLNH_01426 0.0 rne 3.1.26.12 J Ribonuclease E/G family
MEIPOLNH_01427 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
MEIPOLNH_01428 3.1e-40 rpmA J Ribosomal L27 protein
MEIPOLNH_01429 3.7e-215 K Psort location Cytoplasmic, score
MEIPOLNH_01430 3.7e-299 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEIPOLNH_01431 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEIPOLNH_01432 7.6e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
MEIPOLNH_01434 1.2e-30 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEIPOLNH_01435 3.5e-117 nusG K Participates in transcription elongation, termination and antitermination
MEIPOLNH_01436 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
MEIPOLNH_01437 2.8e-177 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MEIPOLNH_01438 1.4e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MEIPOLNH_01439 3.1e-200 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MEIPOLNH_01440 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
MEIPOLNH_01441 7.6e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEIPOLNH_01442 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MEIPOLNH_01443 1.4e-114
MEIPOLNH_01444 6.7e-168 T Pfam Adenylate and Guanylate cyclase catalytic domain
MEIPOLNH_01445 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MEIPOLNH_01446 1.1e-79 ssb1 L Single-stranded DNA-binding protein
MEIPOLNH_01447 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEIPOLNH_01448 1.9e-69 rplI J Binds to the 23S rRNA
MEIPOLNH_01449 3.5e-15 S Parallel beta-helix repeats
MEIPOLNH_01450 2.5e-45 S Parallel beta-helix repeats
MEIPOLNH_01451 6.5e-64 E Domain of unknown function (DUF5011)
MEIPOLNH_01453 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MEIPOLNH_01454 5.1e-129 M Protein of unknown function (DUF3152)
MEIPOLNH_01455 2.3e-184 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEIPOLNH_01456 6.1e-146 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MEIPOLNH_01457 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
MEIPOLNH_01458 0.0 inlJ M domain protein
MEIPOLNH_01459 1.2e-267 M LPXTG cell wall anchor motif
MEIPOLNH_01460 5.9e-211 3.4.22.70 M Sortase family
MEIPOLNH_01461 2e-56 S Domain of unknown function (DUF4854)
MEIPOLNH_01462 2.7e-154 fahA Q Fumarylacetoacetate (FAA) hydrolase family
MEIPOLNH_01463 2.5e-30 2.1.1.72 S Protein conserved in bacteria
MEIPOLNH_01464 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEIPOLNH_01465 1.6e-132 M Mechanosensitive ion channel
MEIPOLNH_01466 3.8e-119 K Bacterial regulatory proteins, tetR family
MEIPOLNH_01467 2e-241 MA20_36090 S Psort location Cytoplasmic, score 8.87
MEIPOLNH_01468 1.2e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
MEIPOLNH_01469 2.3e-64
MEIPOLNH_01471 4.4e-40 K Transcriptional regulator
MEIPOLNH_01472 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MEIPOLNH_01473 3.5e-07 S Scramblase
MEIPOLNH_01478 4e-22 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
MEIPOLNH_01479 1.3e-12 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
MEIPOLNH_01480 3e-237 K Helix-turn-helix XRE-family like proteins
MEIPOLNH_01481 3.7e-54 relB L RelB antitoxin
MEIPOLNH_01482 1.3e-08 T Toxic component of a toxin-antitoxin (TA) module
MEIPOLNH_01483 1.6e-129 K helix_turn_helix, mercury resistance
MEIPOLNH_01484 5e-243 yxiO S Vacuole effluxer Atg22 like
MEIPOLNH_01486 1.1e-200 yegV G pfkB family carbohydrate kinase
MEIPOLNH_01487 1.4e-29 rpmB J Ribosomal L28 family
MEIPOLNH_01488 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
MEIPOLNH_01489 7.2e-218 steT E amino acid
MEIPOLNH_01492 0.0
MEIPOLNH_01493 4.4e-249 U Sodium:dicarboxylate symporter family
MEIPOLNH_01494 6.4e-120 rsmD 2.1.1.171 L Conserved hypothetical protein 95
MEIPOLNH_01495 6.3e-108 XK27_02070 S Nitroreductase family
MEIPOLNH_01496 3.8e-81 hsp20 O Hsp20/alpha crystallin family
MEIPOLNH_01497 4.3e-162 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MEIPOLNH_01498 6.4e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEIPOLNH_01499 1.8e-34 CP_0960 S Belongs to the UPF0109 family
MEIPOLNH_01500 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MEIPOLNH_01501 1.5e-294 ydfD EK Alanine-glyoxylate amino-transferase
MEIPOLNH_01502 3.2e-92 argO S LysE type translocator
MEIPOLNH_01503 2.6e-219 S Endonuclease/Exonuclease/phosphatase family
MEIPOLNH_01504 3.5e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEIPOLNH_01505 9.3e-164 P Cation efflux family
MEIPOLNH_01506 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEIPOLNH_01507 1.5e-135 guaA1 6.3.5.2 F Peptidase C26
MEIPOLNH_01508 0.0 yjjK S ABC transporter
MEIPOLNH_01509 2e-58 S Protein of unknown function (DUF3039)
MEIPOLNH_01510 2.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEIPOLNH_01511 2.4e-103
MEIPOLNH_01512 1e-113 yceD S Uncharacterized ACR, COG1399
MEIPOLNH_01513 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MEIPOLNH_01514 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEIPOLNH_01515 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
MEIPOLNH_01516 7.6e-92 ilvN 2.2.1.6 E ACT domain
MEIPOLNH_01518 9.8e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEIPOLNH_01519 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MEIPOLNH_01520 4.8e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEIPOLNH_01521 3.8e-174 S Auxin Efflux Carrier
MEIPOLNH_01524 0.0 pgi 5.3.1.9 G Belongs to the GPI family
MEIPOLNH_01525 3.6e-189
MEIPOLNH_01527 6.9e-201
MEIPOLNH_01529 3e-120 mgtC S MgtC family
MEIPOLNH_01530 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
MEIPOLNH_01531 6.9e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
MEIPOLNH_01532 3.5e-277 abcT3 P ATPases associated with a variety of cellular activities
MEIPOLNH_01533 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
MEIPOLNH_01534 1.4e-30 K Putative sugar-binding domain
MEIPOLNH_01535 1.5e-96 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
MEIPOLNH_01536 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEIPOLNH_01537 4.4e-157 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MEIPOLNH_01538 7.2e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEIPOLNH_01539 3.9e-201 K helix_turn _helix lactose operon repressor
MEIPOLNH_01540 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MEIPOLNH_01541 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MEIPOLNH_01542 9e-110 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MEIPOLNH_01545 2.2e-174 G Glycosyl hydrolases family 43
MEIPOLNH_01546 2.5e-103 G Glycosyl hydrolases family 43
MEIPOLNH_01547 7.2e-201 K helix_turn _helix lactose operon repressor
MEIPOLNH_01548 9.3e-11 3.2.1.14 GH18 EM Domain of unknown function (DUF5011)
MEIPOLNH_01549 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
MEIPOLNH_01550 6.6e-122 L Protein of unknown function (DUF1524)
MEIPOLNH_01551 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MEIPOLNH_01552 1.5e-305 EGP Major facilitator Superfamily
MEIPOLNH_01553 1.9e-233
MEIPOLNH_01555 4.9e-08 MU Listeria-Bacteroides repeat domain (List_Bact_rpt)
MEIPOLNH_01556 2.5e-34 M S-layer homology domain
MEIPOLNH_01557 0.0 K RNA polymerase II activating transcription factor binding
MEIPOLNH_01558 1e-15
MEIPOLNH_01559 1.4e-18
MEIPOLNH_01560 4.7e-12
MEIPOLNH_01562 7.3e-52
MEIPOLNH_01564 4e-125 3.6.4.12 K Putative DNA-binding domain
MEIPOLNH_01565 2.2e-134 int L Phage integrase, N-terminal SAM-like domain
MEIPOLNH_01567 8.8e-82 sppA OU Serine dehydrogenase proteinase
MEIPOLNH_01568 9.9e-86 K Helix-turn-helix domain protein
MEIPOLNH_01570 3.9e-27
MEIPOLNH_01571 1.6e-53
MEIPOLNH_01573 1.2e-90 3.1.4.37 T RNA ligase
MEIPOLNH_01574 1.2e-25 S phosphoesterase or phosphohydrolase
MEIPOLNH_01576 5.7e-108 S Plasmid encoded RepA protein
MEIPOLNH_01578 2e-48 3.4.22.70 M Sortase family
MEIPOLNH_01579 3.2e-44 S Listeria-Bacteroides repeat domain (List_Bact_rpt)
MEIPOLNH_01581 9.6e-82 M domain protein
MEIPOLNH_01582 8.8e-101
MEIPOLNH_01586 3.3e-41
MEIPOLNH_01587 7.8e-36 L PDDEXK-like domain of unknown function (DUF3799)
MEIPOLNH_01588 1.9e-25
MEIPOLNH_01591 1.8e-89 D ftsk spoiiie
MEIPOLNH_01593 4.5e-160 D ftsk spoiiie
MEIPOLNH_01598 6.6e-17
MEIPOLNH_01600 3.7e-21 flgJ S pathogenesis
MEIPOLNH_01602 2.1e-195 S AAA-like domain
MEIPOLNH_01607 2.3e-07
MEIPOLNH_01609 3.1e-35 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
MEIPOLNH_01612 1.1e-22 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
MEIPOLNH_01614 5.5e-21 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
MEIPOLNH_01616 1.6e-08
MEIPOLNH_01620 1.5e-51 Q methyltransferase
MEIPOLNH_01621 1.7e-19
MEIPOLNH_01628 6.9e-36 S P22_AR N-terminal domain
MEIPOLNH_01629 8.9e-36
MEIPOLNH_01630 7.1e-21 T Pentapeptide repeats (8 copies)
MEIPOLNH_01631 1.3e-07
MEIPOLNH_01633 4.2e-152 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MEIPOLNH_01634 1.3e-61 L TIGRFAM transposase, IS605 OrfB family
MEIPOLNH_01635 2.4e-11 L HTH transcriptional regulator, MerR
MEIPOLNH_01636 1e-08
MEIPOLNH_01644 4.1e-07 D protein tyrosine kinase activity
MEIPOLNH_01647 1.5e-150 S COG0433 Predicted ATPase
MEIPOLNH_01650 9.7e-89 3.2.2.27 NU Tfp pilus assembly protein FimV
MEIPOLNH_01652 4e-25 parA D COG1192 ATPases involved in chromosome partitioning
MEIPOLNH_01654 1.7e-46
MEIPOLNH_01656 4.1e-53 L endonuclease I
MEIPOLNH_01662 4.2e-227 S ATPase domain predominantly from Archaea
MEIPOLNH_01663 2.3e-39
MEIPOLNH_01664 1.3e-25
MEIPOLNH_01665 4.2e-14
MEIPOLNH_01668 1.3e-58 K BRO family, N-terminal domain
MEIPOLNH_01670 1.6e-08
MEIPOLNH_01671 2.2e-09
MEIPOLNH_01672 5.1e-27
MEIPOLNH_01673 5.6e-19
MEIPOLNH_01677 3.4e-40
MEIPOLNH_01678 5.3e-39 L Belongs to the 'phage' integrase family
MEIPOLNH_01679 3.3e-16
MEIPOLNH_01680 3.1e-24 S Putative phage holin Dp-1
MEIPOLNH_01682 1.1e-182 L Psort location Cytoplasmic, score 8.87
MEIPOLNH_01684 2.3e-28 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MEIPOLNH_01685 6.8e-36 3.1.1.53 L Calcineurin-like phosphoesterase
MEIPOLNH_01686 6.1e-18 D nuclear chromosome segregation
MEIPOLNH_01690 2.1e-56 M Sortase family
MEIPOLNH_01692 5.1e-24 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MEIPOLNH_01706 2.4e-53 usp 3.5.1.28 CBM50 S CHAP domain
MEIPOLNH_01708 1.4e-18 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MEIPOLNH_01709 1.8e-28 ssb1 L Single-strand binding protein family
MEIPOLNH_01710 4.4e-109
MEIPOLNH_01711 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
MEIPOLNH_01712 1.8e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MEIPOLNH_01713 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MEIPOLNH_01714 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEIPOLNH_01715 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MEIPOLNH_01716 7.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
MEIPOLNH_01717 2.6e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEIPOLNH_01718 3.6e-246 dgt 3.1.5.1 F Phosphohydrolase-associated domain
MEIPOLNH_01719 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEIPOLNH_01720 2.3e-159 K Helix-turn-helix domain, rpiR family
MEIPOLNH_01721 3.6e-227 K Putative ATP-dependent DNA helicase recG C-terminal
MEIPOLNH_01722 8.8e-23 S Memo-like protein
MEIPOLNH_01724 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEIPOLNH_01725 1.1e-178 adh3 C Zinc-binding dehydrogenase
MEIPOLNH_01726 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEIPOLNH_01727 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEIPOLNH_01728 8.7e-74 zur P Belongs to the Fur family
MEIPOLNH_01729 4.9e-44
MEIPOLNH_01730 2.6e-154 S TIGRFAM TIGR03943 family protein
MEIPOLNH_01731 1.1e-201 ycgR S Predicted permease
MEIPOLNH_01732 2.3e-23 J Ribosomal L32p protein family
MEIPOLNH_01733 8.2e-15 rpmJ J Ribosomal protein L36
MEIPOLNH_01734 7.4e-42 rpmE2 J Ribosomal protein L31
MEIPOLNH_01735 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEIPOLNH_01736 8.8e-47 rpmB J Ribosomal L28 family
MEIPOLNH_01737 2.4e-136 S cobalamin synthesis protein
MEIPOLNH_01738 5.1e-162 P Zinc-uptake complex component A periplasmic
MEIPOLNH_01740 0.0 lysX S Uncharacterised conserved protein (DUF2156)
MEIPOLNH_01741 1.7e-246 S Putative esterase
MEIPOLNH_01742 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MEIPOLNH_01743 6.5e-240 purD 6.3.4.13 F Belongs to the GARS family
MEIPOLNH_01744 2e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MEIPOLNH_01745 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEIPOLNH_01746 1.3e-301 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
MEIPOLNH_01747 2e-32
MEIPOLNH_01748 8e-69 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEIPOLNH_01749 3.4e-32 K DNA-binding transcription factor activity
MEIPOLNH_01750 9.6e-152 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
MEIPOLNH_01751 8.5e-51 S Protein of unknown function (DUF4230)
MEIPOLNH_01752 1.2e-107
MEIPOLNH_01753 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
MEIPOLNH_01754 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MEIPOLNH_01755 2.9e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEIPOLNH_01756 0.0 M Parallel beta-helix repeats
MEIPOLNH_01757 5.4e-228 M Glycosyl transferase 4-like domain
MEIPOLNH_01758 5.9e-199 ltaE 4.1.2.48 E Beta-eliminating lyase
MEIPOLNH_01760 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEIPOLNH_01761 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEIPOLNH_01762 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEIPOLNH_01763 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEIPOLNH_01764 0.0 S Esterase-like activity of phytase
MEIPOLNH_01765 1e-191 EGP Transmembrane secretion effector
MEIPOLNH_01767 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEIPOLNH_01768 3.2e-84 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEIPOLNH_01769 1e-237 carA 6.3.5.5 F Belongs to the CarA family
MEIPOLNH_01770 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MEIPOLNH_01771 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MEIPOLNH_01772 0.0 S Protein of unknown function DUF262
MEIPOLNH_01773 4.1e-116 K helix_turn_helix, Lux Regulon
MEIPOLNH_01774 2.9e-268 T Histidine kinase
MEIPOLNH_01775 1e-97 S Domain of unknown function (DUF5067)
MEIPOLNH_01776 6.6e-132 ybhL S Belongs to the BI1 family
MEIPOLNH_01777 1.1e-167 ydeD EG EamA-like transporter family
MEIPOLNH_01778 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
MEIPOLNH_01779 1.3e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MEIPOLNH_01780 9e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEIPOLNH_01781 1.3e-136 fic D Fic/DOC family
MEIPOLNH_01782 0.0 ftsK D FtsK SpoIIIE family protein
MEIPOLNH_01783 2e-123 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEIPOLNH_01784 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
MEIPOLNH_01785 1.6e-80 K Helix-turn-helix XRE-family like proteins
MEIPOLNH_01786 3.7e-40 S Protein of unknown function (DUF3046)
MEIPOLNH_01787 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEIPOLNH_01788 7.1e-74 recX S Modulates RecA activity
MEIPOLNH_01789 1e-07
MEIPOLNH_01791 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEIPOLNH_01792 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEIPOLNH_01793 6.7e-190 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MEIPOLNH_01794 1.5e-109
MEIPOLNH_01795 4.6e-134 plsC2 2.3.1.51 I Phosphate acyltransferases
MEIPOLNH_01796 0.0 pknL 2.7.11.1 KLT PASTA
MEIPOLNH_01797 2.3e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
MEIPOLNH_01798 1.3e-122
MEIPOLNH_01799 4.1e-180 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEIPOLNH_01800 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MEIPOLNH_01801 4.9e-276 aspA 4.3.1.1 E Fumarase C C-terminus
MEIPOLNH_01802 1e-17 G Major Facilitator Superfamily
MEIPOLNH_01803 3e-25 yozG K Cro/C1-type HTH DNA-binding domain
MEIPOLNH_01804 0.0 lhr L DEAD DEAH box helicase
MEIPOLNH_01805 3.8e-114 parA D AAA domain
MEIPOLNH_01806 7.5e-91 S Transcription factor WhiB
MEIPOLNH_01807 1.6e-41
MEIPOLNH_01808 2.7e-173 S Helix-turn-helix domain
MEIPOLNH_01809 2.9e-118
MEIPOLNH_01810 1.3e-119
MEIPOLNH_01811 6.2e-58
MEIPOLNH_01812 2e-173 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEIPOLNH_01813 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
MEIPOLNH_01814 1.6e-41 P ABC-type metal ion transport system permease component
MEIPOLNH_01815 6.3e-10 P ABC-type metal ion transport system permease component
MEIPOLNH_01816 5e-223 S Peptidase dimerisation domain
MEIPOLNH_01817 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MEIPOLNH_01818 6.4e-40
MEIPOLNH_01819 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MEIPOLNH_01820 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEIPOLNH_01821 4.4e-114 S Protein of unknown function (DUF3000)
MEIPOLNH_01822 2.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
MEIPOLNH_01823 8.1e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEIPOLNH_01824 3.6e-255 clcA_2 P Voltage gated chloride channel
MEIPOLNH_01825 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEIPOLNH_01826 9.4e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEIPOLNH_01827 3.5e-244 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEIPOLNH_01830 1.7e-234 patB 4.4.1.8 E Aminotransferase, class I II
MEIPOLNH_01831 1.2e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MEIPOLNH_01832 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
MEIPOLNH_01833 4.4e-118 safC S O-methyltransferase
MEIPOLNH_01834 4.3e-183 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
MEIPOLNH_01835 8.2e-69 yraN L Belongs to the UPF0102 family
MEIPOLNH_01836 1.2e-293 comM O Magnesium chelatase, subunit ChlI C-terminal
MEIPOLNH_01837 5.7e-283 dprA 5.99.1.2 LU DNA recombination-mediator protein A
MEIPOLNH_01838 1.3e-57 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
MEIPOLNH_01839 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
MEIPOLNH_01840 7.3e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MEIPOLNH_01841 1.6e-157 S Putative ABC-transporter type IV
MEIPOLNH_01842 1e-251 metY 2.5.1.49 E Aminotransferase class-V
MEIPOLNH_01843 1.5e-131 V ABC transporter, ATP-binding protein
MEIPOLNH_01844 0.0 MV MacB-like periplasmic core domain
MEIPOLNH_01845 0.0 phoN I PAP2 superfamily
MEIPOLNH_01846 6.1e-132 K helix_turn_helix, Lux Regulon
MEIPOLNH_01847 0.0 tcsS2 T Histidine kinase
MEIPOLNH_01848 1.2e-263 pip 3.4.11.5 S alpha/beta hydrolase fold
MEIPOLNH_01849 9.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEIPOLNH_01850 4.9e-168 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
MEIPOLNH_01851 1.4e-147 P NLPA lipoprotein
MEIPOLNH_01852 6.5e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
MEIPOLNH_01853 3.2e-184 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
MEIPOLNH_01854 1.6e-205 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEIPOLNH_01855 6.4e-93 metI P Binding-protein-dependent transport system inner membrane component
MEIPOLNH_01856 8.9e-231 mtnE 2.6.1.83 E Aminotransferase class I and II
MEIPOLNH_01857 2.3e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEIPOLNH_01858 5.2e-248 XK27_00240 K Fic/DOC family
MEIPOLNH_01859 1.9e-119 E Psort location Cytoplasmic, score 8.87
MEIPOLNH_01860 5.6e-59 yccF S Inner membrane component domain
MEIPOLNH_01861 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
MEIPOLNH_01862 4.5e-60 S Cupin 2, conserved barrel domain protein
MEIPOLNH_01863 1.1e-258 KLT Protein tyrosine kinase
MEIPOLNH_01864 4.5e-79 K Psort location Cytoplasmic, score
MEIPOLNH_01865 1.1e-149
MEIPOLNH_01866 2.7e-22
MEIPOLNH_01867 9.3e-199 S Short C-terminal domain
MEIPOLNH_01868 3.9e-86 S Helix-turn-helix
MEIPOLNH_01869 2.4e-65 S Zincin-like metallopeptidase
MEIPOLNH_01870 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MEIPOLNH_01871 3.9e-25
MEIPOLNH_01872 1.3e-72 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MEIPOLNH_01873 4.6e-125 ypfH S Phospholipase/Carboxylesterase
MEIPOLNH_01874 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MEIPOLNH_01877 3.2e-289 2.4.1.166 GT2 M Glycosyltransferase like family 2
MEIPOLNH_01878 7.1e-118 3.1.3.27 E haloacid dehalogenase-like hydrolase
MEIPOLNH_01879 4.3e-144 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
MEIPOLNH_01880 3.1e-187 MA20_14895 S Conserved hypothetical protein 698
MEIPOLNH_01881 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
MEIPOLNH_01882 2.4e-237 rutG F Permease family
MEIPOLNH_01883 1.2e-79 K AraC-like ligand binding domain
MEIPOLNH_01885 2.2e-45 IQ oxidoreductase activity
MEIPOLNH_01886 4.2e-136 ybbM V Uncharacterised protein family (UPF0014)
MEIPOLNH_01887 4.5e-135 ybbL V ATPases associated with a variety of cellular activities
MEIPOLNH_01888 2.4e-161 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEIPOLNH_01889 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEIPOLNH_01890 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
MEIPOLNH_01891 2.3e-87
MEIPOLNH_01892 1.1e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MEIPOLNH_01893 7.9e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MEIPOLNH_01894 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MEIPOLNH_01895 2.5e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
MEIPOLNH_01896 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEIPOLNH_01897 7.1e-84 argR K Regulates arginine biosynthesis genes
MEIPOLNH_01898 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEIPOLNH_01899 5.9e-228 S HipA-like C-terminal domain
MEIPOLNH_01900 1.1e-46
MEIPOLNH_01901 5.7e-57
MEIPOLNH_01902 1.5e-81
MEIPOLNH_01903 0.0 topB 5.99.1.2 L DNA topoisomerase
MEIPOLNH_01904 2.7e-85
MEIPOLNH_01905 3e-55
MEIPOLNH_01906 1.8e-40 K Protein of unknown function (DUF2442)
MEIPOLNH_01907 6.9e-52 S Bacterial mobilisation protein (MobC)
MEIPOLNH_01908 5.4e-279 ltrBE1 U Relaxase/Mobilisation nuclease domain
MEIPOLNH_01909 1.1e-163 S Protein of unknown function (DUF3801)
MEIPOLNH_01910 1.7e-284
MEIPOLNH_01912 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MEIPOLNH_01913 3.2e-39
MEIPOLNH_01914 9.3e-31
MEIPOLNH_01915 0.0 U Type IV secretory system Conjugative DNA transfer
MEIPOLNH_01917 3e-09
MEIPOLNH_01918 2.4e-101 dam2 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
MEIPOLNH_01919 5.9e-101 K DNA binding
MEIPOLNH_01920 3.2e-129
MEIPOLNH_01921 3.6e-14 U Type IV secretory system Conjugative DNA transfer
MEIPOLNH_01922 5.4e-205 isp2 3.2.1.96 M CHAP domain
MEIPOLNH_01923 0.0 trsE U type IV secretory pathway VirB4
MEIPOLNH_01924 1e-62 S PrgI family protein
MEIPOLNH_01925 3.3e-139
MEIPOLNH_01926 8.9e-26
MEIPOLNH_01927 0.0 XK27_00515 D Cell surface antigen C-terminus
MEIPOLNH_01928 1.5e-79
MEIPOLNH_01929 6.9e-19
MEIPOLNH_01930 1.2e-73 S EcsC protein family
MEIPOLNH_01932 3.6e-22 L DNA integration
MEIPOLNH_01933 3.3e-26
MEIPOLNH_01934 4.8e-145 fic D Fic/DOC family
MEIPOLNH_01935 3.7e-246 L Phage integrase family
MEIPOLNH_01936 3e-07
MEIPOLNH_01937 1.1e-49 relB L RelB antitoxin
MEIPOLNH_01938 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
MEIPOLNH_01939 1.9e-208 E Belongs to the peptidase S1B family
MEIPOLNH_01940 6.9e-12
MEIPOLNH_01941 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEIPOLNH_01942 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MEIPOLNH_01943 1.4e-47 S Domain of unknown function (DUF4193)
MEIPOLNH_01944 4.1e-187 S Protein of unknown function (DUF3071)
MEIPOLNH_01945 1.3e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
MEIPOLNH_01946 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MEIPOLNH_01947 0.0 lhr L DEAD DEAH box helicase
MEIPOLNH_01948 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
MEIPOLNH_01949 1.9e-155 S Domain of unknown function (DUF4357)
MEIPOLNH_01950 2.4e-30
MEIPOLNH_01951 1e-178 L Phage integrase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)